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135
427e4fc4-c2f9-48bf-91ed-6a0f4f0b4889
Opioid tolerance develops to all of the following actions, except:
Miosis
Analgesia
Euphoria
Nausea and vomiting
0a
multi
Ans. is 'a' i.e., Wasis Tolerance is exhibited to most actions of morphine except for miosis and constipation.
Pharmacology
null
b97ad132-b856-45b3-91cd-048c753ee6f2
Which among the following help in folding of Proteins
Proteosomes
Chaperones
Glycoproteins
Proteases
1b
single
Chaperones also called as heat shock proteins are auxillary proteins that assist in protein folding.
Biochemistry
null
5fe3f11e-c2ee-4778-8e10-df40bcef5ac7
A 46- Years old female presented at the eye OPD in a hospital. Her vision in the right eye was 6/60 and in left eye 3/60. Under the National Programme for Control of Blindness, she will be classified as
Low vision
Socially blind
Economically blind
Normal vision
0a
multi
Low Vision - Visual Acuity - NPCB, India Category 1 - <6/18 – 6/60 - Low Vision Category 2 - <6/60 – 3/60 - Economic Blindness Blindness Category 3 - <3/60 – 1/60 - Social Blindness Category 4 - <1/60 – PL+ - Manifest Blindness Category 5 - PL– - Absolute Blindness
Social & Preventive Medicine
null
90415f43-6067-4a5a-a95d-1eeb1ff7ed76
Function of superior oblique muscle is:
Intorsion, adduction and depression
Intorsion, abduction and elevation
Intorsion, abduction and depression
Extorsion, abduction and depression
2c
single
The primary action of the superior oblique muscle is intorsion (internal rotation), the secondary action is depression (primarily in the adducted position) and the teiary action is abduction.
Anatomy
null
61471cf6-298e-4dd8-9e8e-80de22307e19
Which of the following inhalational agent can cause coronary steal phenomenon-
Isoflurane
Sevoflurane
Desflurane
Halothane
0a
single
Isoflurane more than other inhalational agents increases coronary blood flow many times beyond that of the myocardial oxygen demand, thereby, creating potential for "Steel", steel is diversion of blood from a myocardial bed with limited or inadequate perfusion to a bed with more adequate perfusion.
Anaesthesia
Inhalational Anesthetic Agents
e33e61bf-5461-44c4-bb94-42a9983afee1
Screening are for trachoma is:
Below 5 years school child only
1-9 years
9-14 years
5-15 years
1b
single
Ans. b. 1-9 years
Social & Preventive Medicine
null
3a60d418-1566-4639-9396-6ed299ce6150
Slowest conduction is seen in the following pa of the cardiac conducting system:
SA node
Purkinje fibres
AV node
Bundle of his
2c
single
Depolarization initiated in the SA node spreads radially through the atria, then converges on the AV node. Atrial depolarization is complete in about 0.1 s. Because conduction in the AV node is slow, a delay of about 0.1 s (AV nodal delay) occurs before excitation spreads to the ventricles. This delay is shoened by sti...
Physiology
null
01328973-22a3-4999-a2db-82cff745108b
What is the best stimulus for release of vasopressin
Hypotonicity of extracellular fluid
Hypeension
Hypotension
Hypo-osmolality of extracellular fluid
2c
single
Best / most impoant stimulus for ADH - Hypeonicity Next - hypotension Water deficit | |extracellular osmolarity |Osmoreceptors | ADH secretion (posterior pituitary) | |Plasma ADH | H2O permeability in |distal tubules. Collecting ducts | |H2O reabsorption | |H2O excreted 1. | Osmolality / tonicity 2. Aerial baroreceptor...
Physiology
FMGE 2018
1b1eac13-64ae-46b3-a2bd-c43e641f8355
Despite its "age," penicillin G remains the drug of choice in the treatment of infections caused by
B. fragilis
T. pallidum
H. influenzae
E. coli
1b
multi
Indications for the use of penicillin G are currently limited for a number of reasons. The drug has a narrow spectrum, is susceptible to beta-lactamases, and may cause hypersensitivity, and alternative antibiotics are available. However, penicillin G remains the drug of choice in syphilis, usually given IM as benzathin...
Pharmacology
Anti Microbial
135abdc5-56ba-4a87-8d7e-7eb11e115fb0
Components separation technique in hernia helps by:
Lesser infection
Decrease suture line tension
Lower recurrence
None of the above
1b
multi
Ramirez first described the components separation technique. Components separation entails the creation of large subcutaneous flaps lateral to the fascial defect followed by incision of the external oblique muscles and, if necessary, incision of the posterior rectus sheath bilaterally. Fascial releases allow for primar...
Surgery
null
6a7041bd-e26b-41f9-a6ee-0b25ce5fb5d9
Volatile agent which causes most renal toxicity is
Ether
Isoflurane
Methoxyflurane
Sevoflurane
2c
single
Methoxyflurane is most metabolized and produces more than 80 micromol/litre of flouride in blood. The amount of fluoride ions produced: Methoxyflurane: 50uM Sevoflurane: 20-30 uM Enflurane: 20uM Isoflurane and desflurane: 5uM
Anaesthesia
Inhalational Anesthetic Agents
c6f70e40-6b28-459b-8b45-24344493fb98
Bacteria with tuft of flagellae at one end are called -
Monotrichate
Peritrichate
Bipolar
Lophotrichate
3d
multi
Ans. is 'd' i.e., Lophotrichate Two projections from the cells are impoant in relation to bacteria? i) Flagella ii) Fimbriae Flagella Flagella are the organs of locomotion. All motile bacteria except for spirochetes possess flagella. Flagella are made up of protein antigen flagellin Though flagella of different genera ...
Microbiology
null
5407a05c-1275-4745-be90-89f96e7e92f9
Positive ECG sign(s) of ischemia in Tread mill test is/ are-
Upsloping depression of the ST segment mV below baseline
Downsloping depression of the ST segment >0.1 mV below baseline
Junctional ST-segment
Tachycardia
1b
single
Answer- B. Downsloping depression of the ST segment >0.1 mV below baselineThc ischemia ST:-segment respone generally is defined as flat or downsloping depression of the ST segmant >O.1 mVbelow baseline (i.e., tha PR segnent) and lasting longer than O.08s.Upsloping or junctional ST-segment changes are not considered cha...
Medicine
null
87ea4c1a-c47d-4b6f-8e0e-41bcb354c9b7
The splenic aery usually follows a touous course along which of the following structure?
Left kidney
Greater curvature of the stomach
Pancreas
Transverse colon
2c
multi
The splenic aery, the largest branch of the celiac trunk, follows a touous course posterior to the omental bursa, anterior to the left kidney, and along the superior border of the pancreas.
Microbiology
All India exam
cc1228bc-3756-4b32-b8ce-2e41466a01d0
Cetuxirnab (an EGFR antagonist) can be used in
Palliation in head and neck cancer
Anal canal ca
Gastric ca
Lung ca
0a
multi
Palliation in head Neck cancer Cetuximab is a monoclonal antibody that acts against EGFR (Epidermal growth factor receptor). EGFR is a signalling protein that normally controls cell division. In some cancers this is altered to cause uncontrolled cell division. Cetuximab attaches itself to EGFR and prevents the receptor...
Pharmacology
null
5aff9ea9-1452-48f7-84af-dd06c3a3379f
Spanish windlass is an example of which of the following methods of crime?
Bansdola
Garrotting
Throttling
Mugging
1b
single
In garrotting, a ligature is thrown over the neck of the victim and is quickly tightened by twisting it with a lever. In Spanish windlass, an iron collar is tightened by a screw. Ref: Essentials of Forensic Medicine and Toxicology by Narayan Reddy, 21st Edition, Page 300.
Forensic Medicine
null
30cbe4e9-187f-4e6f-80b5-f12e5b320b9c
Investigation of choice for cryptococcosis is -
Culture
India ink
PCR
Acid faststain
1b
single
Ans. is 'b' i.e., India ink o C. neoformans is best demonstrated in CSF by direct microscopy. The capsule is seen as a clear halo around the yeast cells in unstained wet preparations of CSF mixed with a drop of India ink or nigrosine. Methenamine silver stain would be the best choice for a tissue sample.CRYPTOCOCCUS NE...
Microbiology
Mycology
7ea04e79-9176-47b2-8a89-bdc039e578a7
Cause of nail bed infarctions a) H.D b) Wegener's granulomatosis c) Infective endocardities d) Surge strauss syndrome e) PAN
abc
bc
bd
cd
1b
single
null
Medicine
null
0aa3ef76-b47b-4753-b159-0c255bdeb774
Demand of fetus for iron is evident after_____ weeks
10
20
25
30
2c
single
Ans. c (25 weeks) (Ref. Nelson Textbook of Pediatrics 17th/pg. 545)IRON REQUIREMENT IN PREGNANCY# Mineral supplementation is not needed in healthy women.- The exception is iron.# The iron requirements of pregnancy are total about 1 gram.# Demand of fetus for iron is evident in last 12 weeks of pregnancy.
Gynaecology & Obstetrics
Miscellaneous (Gynae)
5b4e1d67-7453-4e1e-a99c-c1d36bcae0ad
All are true about the features of erythromelalgia , EXCEPT:
Unknown aetiology
Thrombocytosis is seen
Digital infarction is seen
Treatment is steroids
3d
multi
Erythromelalgia Syndrome of unknown etiology It is associated with thrombocytosis Manifested by erythema, warmth, and pain of the affected appendage and occasionally digital infarction. It usually respond to salicylates. Ref: Harrison, E-18,P-903
Medicine
null
c0924c0d-30c1-4625-a2ce-fe939c358b92
Organism most frequently associated with urinary tract infections is
Neisseria gonorrhea
Escherichia coli
T-strain mycoplasma
Streptococcus fecalis
1b
single
null
Microbiology
null
88e2cf55-87a1-4d8f-ad51-97f3be6759e3
The most impoant constituent in soda lime for reabsorption of CO2 in a closed circuit
Sodium hydroxide
Barium hydroxide
Calcium hydroxide
Potassium hydroxide
2c
single
Sodalime is most common Co2 absorbant . Indicators added to sodalime changes the color of sodalime . It contains 94% Ca(OH)2 , 5%NaOH,1% KOH.
Anaesthesia
Anaesthetic equipments
fea270ba-28a5-44c4-99b3-fa3d7cc4a144
Osteomalacia is adverse effect of :
Primidone
Phenytoin
Carbamazepine
Valproic acid
1b
single
null
Pharmacology
null
c9bb1ece-91ab-4ab8-82f7-a7c2e518001c
Disease transmitted from men to animals:
Antropozoonoses
Zooanthroponoses
Amphixenoses
Aptozoonoses
1b
single
Ans. b. Zooanthroponoses
Microbiology
null
20412a44-ea6d-42a8-820e-5d5c121f40f2
X–ray film should be taken in closed pneumothorax during-
Deep expiration
Deep inspiration
In supine position
In lateral position
0a
single
Usual chest X-ray is PA view in full inspiration. For pneumothorax PA view in full expiration is the most appropriate view.
Radiology
null
89a53b03-bd40-46f7-ba75-2c2296e31401
Lifespan of RBCs in premature neonate
120 days
60 days
90 days
40 days
3d
single
Adults - 120 days. Term infant - 60 - 90 days. Premature neonate - 35 - 50 days.
Medicine
null
a6f8902b-e77f-4277-a26c-acb65c83017f
Which of the following is a Type 2 Hypersensitivity reaction?
Chronic Kidney Rejection episode
Autoimmune Hemolytic anaemia
Arthus reaction
Mitsuda reaction
1b
single
Ref: Robbins E-Book, P 135* Choice A is type of type 4 Hypersensitivity reaction.* Choice C is type of type 3 Hypersensitivity reaction.* Choice D is type of type 4 Hypersensitivity reaction.Examples of type ii hypersensitivityDiseaseTarget antigenMechanism of diseaseClinicopathologic ManifestationsAutoimmune hemolytic...
Pathology
Immunity
a23d7d80-e307-4d8f-9e49-397fae50eea0
Purple toe syndrome is associated with which of the following drugs?
Warfarin
Phenytoin
Theophylline
Thalidomide
0a
single
null
Medicine
null
e182eb98-38b5-431c-8976-4077b3624c4a
The gene that predisposes to retinoblastoma is located at -
Chromosome 13q14
Chromosome 15q11
Chromosome 11p13
Chromosome 22q11
0a
single
Robbins basic pathology 6th edition. Chapter Neoplasia. page no. 287. The mutations required to produce retinoblastoma involve Rb gene located on chromosome 13q14.
Pathology
General pathology
9d3228ec-0f95-43f6-b1f8-c4238379998c
A 23-year-old female presented with jaundice and pallor for 2 months. Her peripheral blood smear shows the presence of spherocytes. The most relevant investigation to arrive at a diagnosis is;
Reticulocyte count
Osmotic fragility test
Coombs test
Tests fro PNH
2c
multi
Ans. c. Coombs test (Ref: Robbins 9/e p643-644; Chandrasoma and Taylor 3/e p401)History of jaundice in a 23-year old female with pallor and spherocytes in peripheral blood points towards the diagnosis of autoimmune hemolytic anemia (AIHA). The diagnostic test for AIHA is the antiglobulin test (Coombs' test).Autoimmune ...
Pathology
Blood
a54478c8-ee11-4f3e-a20a-161888207f43
A 57 year old male suffering from acute pancreatitis develops sudden onset breathlessness with a CVP< 18mmHg. The chest xray shows bilateral infiltrates. The possible diagnosis is
ARDS
Myocardial infarction
Congestive left hea failure
Pulmonary embolism
0a
single
Answer- A. ARDSARDS CriteriaAcute, meaning onset over 1 week or less.Bilateral opacities consistent with pulmonary edema must be present and may be detected on CT or chest radiograph.PF ratio < 300 mmHg with a minimum of 5 cmH20 PEEP (or CPAP).CVP < l8 mmHg.
Surgery
null
ad36da7d-aca8-40eb-a434-8fe472ba2f13
Partner treatment is not required in all of the following except
Bacterial vaginosis
Herpes genitalis
Candidal vaginitis
Trichomoniasis
3d
multi
Trichomoniasis is acquired by sexual route by tranmission of T.vaginalis and hence partner treatment is required.
Dental
null
89a1c078-8c62-4dca-8526-dce1ebed23a3
A 10-degree decrease in temperature causes decreases in cerebral metabolic rate by :
10%
30%
50%
70%
3d
single
D i.e. 70%With each degree fall in temperature, the metabolic rate is reduced by 70%.So by reducing temperature by 10-degree celsius, the metabolic rate is reduced by 70%.Cerebra coex is protected for 10 mins at 30-degree celsius and for 1 hr at 15-degree celsius.
Physiology
null
5590d6d1-767a-4449-bb3e-2fe0bff15fb8
For diagnosis of Acute Rheumatic fever, essential is:
Prior h/o rheumatic fever
Recent sore throat infection
1 major and 2 minor criteria's
Erythema marginatum
2c
single
null
Medicine
null
35fa273b-6dca-4b4a-88af-8a4622ec26a5
The polysaccharide capsule of following bacteria has in role in their infectivity except
Haemophilus influenza
Neisseria meningitides
Streptococcus pneumoniae
Bordetella peussis
3d
multi
The polysaccharide capsule of Bordetella peusis has no significant role in its infectivity. Bordetella fresh cultures demonstrated capsules but its virulence is mainly toxin-mediated.
Microbiology
All India exam
473dafee-ca66-48b1-8a4a-6ea59e08be7c
Therapeutic aboion was accepted by -
Declaration of Geneva (1948
Declaration of Oslo (1970)
Declaration of Helsinki
Declaration of Tokyo
1b
single
Therapeutic aboion In 1970 the World Medical Association drew up a Statement on Therapeutic Aboion. This code, known as the Declaration of Oslo, was amended by the 35th World Medical Assembly, Venice, Italy in October 1983 and states: The first moral principle imposed upon the physician is respect of human life from it...
Social & Preventive Medicine
Non communicable diseases
dfa488d6-0f6f-46dd-ac1e-048a97334493
IPC 94 related to
Consent in emergency situations
Criminal responsibility of an act done by a person < 7 years
Criminal responsibility of an act done by an intoxicated person
Criminal responsibility of an act Compelled by threats
3d
single
Section 94:- Act to which a person is compelled by threats Except murder, and other offences punishable with death, nothing is an offence which is done by a person who is compelled to do it by threats of instant death Explanations A perso seized by a gang of dacoits, and forced, by threat of instant death, to do a thin...
Forensic Medicine
Legal sections
3a26dc74-9921-485d-9e6f-d5ea8f7aa738
Spinal shock is characterized by all of the following, Except :
Spastic paralysis
Flaccid paralysis
Urinary Bladder involvement
Areflexia
0a
multi
Answer is A (Spastic paralysis): Spinal Shock is associated with Flaccid paralysis and not Spastic paralysis Spinal shock Flaccid Paralysis (complete motor paralysis) Areflexia Sensory loss (anesthesia to all modalities) Bladder Involvement (usually areflexic bladder with urinary retention)
Medicine
null
eb230ba8-ba43-4916-b056-d74c1711f7e0
Unequal division of the conus cordis resulting from anterior displacement of the conotruncal septum gives rise to
Persistent truncus aeriosus
Coarctation of aoa
Tetralogy of Fallot
Transposition of great vessels
2c
multi
C. i.e. Tetralogy of Fallot
Anatomy
null
9bc9e2d0-4924-451a-b2fd-faff1ef68f03
Most common postprandial motility is seen in
Ascending colon
Transverse colons
Descending colon
Sigmoid colon
3d
single
It&;s sigmoid colon Tonic and phasic colonic motility and compliance of the transverse and sigmoid colon were therefore assessed using a combined barostat-manometry assembly in 22 healthy subjects. Measured colonic compliance was corrected by subtraction of the compliance of the closed barostat system. The mean (SEM) p...
Physiology
G.I.T
7f8aa840-849e-4bfd-8807-47b6fcf488ad
Which is not a tumor suppressor gene?
WT-1
Rb
p53
RAS
3d
single
D i.e. RASGenes that promote autonomous cell growth in cancer cells are called oncogenes and their normal cellular counterpasQ are called proto-oncogenesQ. RAS is an oncogeneQ.Growth factorGrowth factor receptorsProteins involved in signaltransductionNuclear regulatory proteinsProtooncogeneEncodeProtooncogeneEncodeProt...
Biochemistry
null
f99a5c3e-4767-466f-b8c4-f77020447b3f
Which of the following is not a clinical presentation of Peripheral arterial occlusion
Pain
Pallor
Anesthesia
None of the above
3d
multi
null
Surgery
null
f2d81ade-8b2f-4ff9-af06-46c94641584d
Frequent periodontal abscesses appear to be an important periodontal feature in
Nutrition deficiency
Diabetes Mellitus
Hormonal imbalance
Cardiovascular diseases
1b
single
null
Dental
null
f816ac0b-8370-4b75-8232-904b019fa44c
The following are related to corpous luteum except
Luteinised granulosa cells produce progesterone
Estrogen continues to be produced by the luteinised granulosa cells
Luteolysis is due to estrogen, PGF2a and endothelin
The peak steriod production is between 23 and 25th day
3d
multi
The estrogen attains a lower level and maintains a plateau curve as against a peak rise in follicular phase. Progesterone attains its highest peak about 8 days(22nd day of menstual cycle) after the LH peak Regression of corpus luteum is attrubuted to fall in LH level and rise in the level of estrogen and PGF2alpha. Ref...
Gynaecology & Obstetrics
Reproductive physiology and hormones in females
5533e6fb-1470-41cf-8572-904130275cd7
Best Diagnosis for Ectopic gastric mucosa of meckels diveiculum -
Fluoroscopy
Occult blood test in stool
Ultrasound abdomen
Radionuclide scan
3d
single
Ans is 'd' ie. Radionuclide scan "If a Meckels diveiculum is suspected because of repeated gastrointestinal haemorrhage the abdomen can be scanned after the injection of 99Tc-labelled peechnetate intravenously. This may localise heterotopic gastric mucosa revealing the site of a meckels diveiculum in 90% of cases." - B...
Surgery
null
a377e348-913f-4403-a8ec-9a2c3443e637
Autoimmune hepatitis asso with -a) Anti LKM antibodyb) ANAc) ANCAd) SLA-antibody
acd
abd
abc
ab
1b
single
null
Medicine
null
1067bf18-3c69-4a60-a837-db0fcb5b2071
A 40-yr-old female who is known as the case of ischemic heart disease (IHD) is diagnosed with having hypothyroidism. Which of the following would be the most appropriate line of management for her -
Start levothyroxine at low dose
Do not start levothyroxine
Use levothyroxine
Thyroid extract is a better option
0a
multi
null
Medicine
null
fd576a7d-fdbe-44ca-8779-ee4a9ca2553a
A 2-year-old male is admitted to the hospital with testicular pain. Physical examination reveals an enlarged scrotum. An otoscope is placed beneath the lateral side of the scrotum and the testis is transilluminated through the scrotal sac. Which of the following best describes the signs observed in this patient?
Varicocele
Rectocele
Cystocele
Hydrocele
3d
single
(d) Source: GAS 448-451; GA 224-225 As seen in the photograph, the swollen scrotum contains mostly a clear fluid. Since hydrocele is the accumulation of fluid between the visceral and parietal layers of the tunica vaginalis, this condition best accounts for the findings in this patient.
Anatomy
Abdomen & Pelvis
696561c7-ce6e-4f8c-beb9-760e99c3681a
The most life threatening complications of septic abortion includes:
Peritonitis
Renal failure
Respiratory distress syndrome
Septicemia
2c
single
Ans. is c, i.e. Respiratory distress syndromeRef. Dutta Obs. 7/e, p 164, 165; COGDT 10/e, p 987According to COGDT 10/e, p 987"The most common cause of death in patients with this condition is respiratory insufficiency secondary to ARDS."According to Williams Obs. 23/e, p 222"With severe sepsis syndrome, acute respirato...
Gynaecology & Obstetrics
Abortion
c0398e2b-0e67-4c66-8e03-afb3b334bd42
Plateau phase of cardiac cycle is due to -
Na+
K+
Ca2+
Cl-
2c
single
Ans. is 'c' i.e., Ca2+ o Phase 0 (phase of rapid depolarization)- opening of fast sodium channels with Na4 influxo Phase 1 (initial phase of rapid repolarization)- closure of fast sodium channelso Phase 2 (plateu phase)- opening of voltage gated slow Ca++ channels with calcium influx.o Phase 3 (final repolarization)- o...
Physiology
Heart, Circulation, and Blood
4e9b225e-10b5-4e79-ab02-1a36b34beac8
Stimulant drug is given to child for ?
Conduct disorder
Speech developmental disorder
Pervasive disorder
ADHD
3d
single
Ans.D. ADHDStimulants (like methylphenidate, dextramphetamine) are the drugs of choice for ADHD.
Psychiatry
null
7663252d-ad65-4d44-affd-b9be4d680bf1
CNS tumor seen in Von Hippel Lindau syndrome is-
Meningioma
Cerebellar hemangioblastoma
CNS lymphoma
Glioma
1b
single
null
Medicine
null
48694268-4535-4380-aa45-bd6498912b4f
The food item associated with B.cereus emetic food-type poisoning is:
Meat
Milk products
Canned food
Fried rice
3d
single
Option 1, 4 Food items associated: Diarrheal type - Meat, vegetables, dried beans, cereals. Emetic type - Rice (Chinese fried rice). 1. Bacillus cereus food poisoning is of two types. Emetic type and Diarrheal type abdominal cramps are common features in both. Other features are: a) Emetic Type: History of intake of fr...
Microbiology
Systemic Bacteriology (Gram Positive Bacilli, Gram Negative Bacilli)
9372a25a-2965-4613-986b-a968cace35ac
A child was operated for small intestine mass with intussusception and after the operation the tumor was diagnosed in histological section. Which is the most likely tumor associated?
Carcinoid
Villous adnoma
Lymphoma
Smooth muscle tumor
2c
multi
SMALL-BOWEL NEOPLASM - MC tumor of small bowel: Leiomyoma > Adenoma - MC tumor of small bowel in children : Lymphoma - MC malignant tumor of small bowel : Adenocarcinoma >Carcinoid - MC site of small bowel malignancy, carcinoids, lymphoma: Ileum
Surgery
Intestinal obstruction
3bd79e14-0e15-4667-98b2-478c830f28d9
For elimination of measles, vaccine Coverage should be (in successive brith cohart) -
>70%
> 80%
>90%
> 95%
3d
single
Ans. is 'd' i.e., > 95% o WHO's measles elimination strategy comprises a three part vaccination strategy, i.e.:-i) Catch-up - One-time, nationwide vaccination campaign targeting usually all children aged 9 months to 14 years regardless of history of measles disease or vaccination status.ii) Keep-up - Routine services a...
Social & Preventive Medicine
Measles
dc02803f-537e-49b3-8666-3dd6b043eef5
In LVH, SV1 +RV6 is more than mm
25
30
35
45
2c
single
Ans. is 'c' i.e., 35 Arrhythmias by Kathryn Lewis p. 219] o In LVH, SV-1 plus RV-6 is more than 15 mm. To diagnose the left ventricular hyperophy on ECG one of the following criteria should be met :? The sokolow-lyon criteria is most often used - R in V, or V6 + 5 in V > 35 mm in men The cornell-criteria has different ...
Medicine
null
d900b9c4-f6e0-47e3-96c4-ed4f81f41c73
Serum marker of rickets is -
Acid phosphates
Alkaline phoshpatase
Decreased serum calcium
Urinary posphates
1b
single
Ans. is 'b' i.e., Alkaline phosphataseo Amongst the given options, alkaline phosphatase is best because it is raised in all type of rickets.o The primary (Basic) investigations in a child of rickets are :?Serum calciumSerum phosphorusAlkaline phosphataseo If patient does not respond to calcium and Vit D therapy, second...
Pathology
null
d7e13a00-95ac-4322-b18e-1c3056c7ba24
The adjuvant used in IL PT vaccine is -
Al
Mg
Zn
Formaldehyde
0a
single
null
Social & Preventive Medicine
null
241dafe0-8b30-437b-9869-97f33228ea8e
Which of the following is seen in Schwannoma?
Storiform pattern
Spindle cells
Antoni A and Antoni B pattern
Target cells
2c
single
Ans. c. Antoni A and Antoni B pattern (Ref: Robbins 9/e p257. 854, 8/e p1340)Antoni A and Antoni B pattern is seen in schwannoma.'Schwannoma: In the Antoni AQ pattern of growth, elongated cells with cytoplasmic processes are arranged in fascicles in areas of moderate to high cellularity and scant stromal matrix; the 'n...
Pathology
Tumors
352d05ff-814f-4d68-9b59-9b541cce1b7b
RDA in infant of Vit A is -
350 g
450 g
600 g
1000 g
0a
single
- daily intake of vitamin A recommended by ICMR for infants is 350 mcg retinol. - daily intake of vitamin A recommended by ICMR for infants is 2800 mcg beta carotene. Reference : Park's textbook of preventive and social medicine, 23rd edition, pg no:616 <\p>
Social & Preventive Medicine
Nutrition and health
5506accf-c8a2-4e5a-98cf-e116ebe61dcd
Synthetic Orygen carrier is made up of_
Iron
Bronze
Molybdenum
Flurine
3d
single
Ans. is 'd' i.e., FlurineBlood doping is a form of fraudulent increase in the oxygen carrying capacity of a person, widely used to improve the aerobic capacity of athletes.
Biochemistry
null
9ba25c78-f8ed-4b84-9242-05b898981830
Which of the following is not true for hemophilia A
Hemophilia A is due to deficiency of factor VIII
In hemophilia A females are carriers
Desmopressin is useful in the management of hemophilia A
Levels of factor VIII Less than 50% are associated with spontaneous hemorrhage
3d
multi
null
Pathology
null
62c97ef5-fce0-43eb-9c11-0123afae3256
At usual therapeutic doses (blood levels), expected effects of aspirin include which of the following?
Efficacy greater than acetaminophen as an anti-inflammatory agent
Efficacy less than acetaminophen for relieving simple headache pain
Inhibited growth, or killing, of bacteria that cause fever as a symptom of infection
Inhibition of leukotriene synthesis, protection against bronchopasm in asthmatics
0a
single
Aspirin inhibits synthesis of prostaglandins that are impoant in the pathophysiology, signs, and symptoms of a host of inflammatory or ahritic states. It does so, of course, by inhibiting both COX-I and -2. Acetaminophen lacks this propey, and so acetaminophen is much less efficacious for managing inflammation. Aspirin...
Pharmacology
Autacoids
a842bf1e-946a-43fd-ab71-fdfd1afdb41d
The most impoant stimulus controlling the level of resting ventilation is:
PO2 on peripheral chemoreceptors
PCO2 on peripheral chemoreceptors
pH on peripheral chemoreceptors
pH of CSF on central chemoreceptors
3d
single
The most impoant stimulus comes from the pH of the CSF on the central chemoreceptors. The other choices are incorrect: The effect of PO2 on the peripheral chemoreceptors under normoxic conditions is very small. Changes in PCO2 do affect the peripheral chemoreceptors, but the magnitude is less than that for the central ...
Physiology
Respiratory System Pa 2
f6d46f53-4a75-4a02-9d6c-b48e4e72fb2e
Intraocular calcification in eye in child -
Toxocara
Retinoblastoma
Angiomatosis retinae
Malignant melanoma of choroid
1b
single
Ans. is 'b' i.e., Retinoblastoma o In retinoblastoma, there are areas of necrosis and calcification.o In the presence of calcification, endophytic retinoblastoma gives the typical 'cottage cheese' appearance.
Ophthalmology
Intra Ocular Tumour
c12b88a5-f54a-4383-b9ff-e4a1938b4b7d
Treatment of carcinoma cervix stage MB include
Concurrent chemoradiation
Surgery
Neoadjuvant chemotherapy followed by radiotherapy
Only radiotherapy
0a
single
Ans. a. Concurrent chemoradiation
Gynaecology & Obstetrics
null
073a461d-1098-4622-8e49-c3e9a4b29b51
Predominant class of immunoglobulin during primary immune response is -
IgA
IgE
IgM
IgG
2c
single
IgM antibodies appear early in the course of an infection and usually reappear, to a lesser extent, after fuher exposure. Ref: Ananthanarayan & Parkers textbook of microbiology 9th edition pg:98
Microbiology
Immunology
a74e8e10-d3b0-4404-9fc4-11e1beaec6c6
All are true of actue rheumatic fever except ?
Aschoff nodule in mycoacardium
Focal myocardial fiber necrosis
Microthrombi in aeriole
Lymphocytic myocarditis
2c
multi
Ans. is 'c' i.e., Microthrombi in aeriole
Pathology
null
b22afb18-16bf-4f1b-8dd2-a3d0afe8d4f0
Man with gynaecomatsia and infeility, cause?
Cimetidine
Omeprazole
Erythromycin
Digitalis
0a
single
Cimetidine (but not other H2 blockers) has antiandrogenic action. It displaces dihydrotestosterone from its cytoplasmic receptor. It also increases plasma prolactin and inhibits degradation of estradiol by liver. High doses given for long periods have produced gynaecomastia, loss of libido, impotence and temporary decr...
Medicine
Endocrinology
94027983-e50e-4229-a8f9-76658b3f4def
Wrong about dhatura seeds is ?
Kidney shaped
Odourless
Yellow brown
Convex smooth surface
3d
single
Ans. is 'd' i.e.,Convex smooth surface Features of Dhatura sees are :-Large & thickOdourlersKidney - shapedLaterally compressed and double edged at convex border (not smooth)Yellowisk brown Bitter
Forensic Medicine
null
33ed8a81-8b1b-4ef6-985c-46bc1bebb7a4
Predisposing factor for carcinoma vulva is all Except
Smoking
HPV
Fibroepithelial polyp
Leukoplakia
2c
multi
The etiologic role of ceain viruses in carcinogenesis, paicularly high-risk HPV types 16 and 18, in these sites is well documented. Mention has already been made about the preceding stage of vulval epithelial disorders, paicularly squamous hyperplasia, in the development of these lesions. Ref: HARSH MOHAN TEXTBOOK OF P...
Pathology
miscellaneous
1722860e-b0d8-4f82-920b-507974406e04
Sharp pain is transmitted by which type of fibers
Aa
Ab
Ad
C
2c
single
Sharp pain is transmitted by A delta nerve fibres Ref: guyton and hall textbook of medical physiology 12 edition page number: 698,699,700
Physiology
Nervous system
c07c8c8e-293e-426f-b2c0-b6ef9df7ae33
Virulence factors for meningococci ?
Capsule
Pili
Endotoxin
All
3d
multi
Ans. is 'a' i.e., Capsule; 'b' i.e., Pili & 'c' i.e., Endotoxin The capsular polysaccharide - It is a major virulence factors - It has antiphagocytic and antibactericidal propeies. - Based on capsular polysaccharide, meningococci have been divided into serogroups. Outer membrane proteins - Pili - Facilitate adhesions -...
Microbiology
null
c13ead24-4208-4dec-9ad4-0df292a35b3b
Modes of death are all except -
Syncope
Coma
Asphyxia
Shock/molecular death
3d
multi
Modes of death are coma, syncope and asphyxia whereas molecular death is a type of death. Dr. Narayana Reddys Synopsis of Forensic Medicine & Toxicology 27th edition pg.66,67
Forensic Medicine
Death and postmortem changes
4b9e910e-526c-48b4-8b7f-312451fe55d2
Which is not an assisted reproduction technique:
GIFT
ZIFT
IVF and ET
Artificial insemination
3d
single
Assisted reproductive technology (ART) is the technology used to achieve pregnancy in procedures such as fertility medication, in vitro fertilization and surrogacy. It is reproductive technology used primarily for infertility treatments and is also known as a fertility treatment. It mainly belongs to the field of repro...
Gynaecology & Obstetrics
null
462b7a2d-f433-4ed6-a617-152431eed896
Nausea, Vomiting, Blue line on gums, Wrist/ foot drops, Pallor, Colic are manifestations of poisoning due to
Mercury
Arsenic
Organic lead
Inorganic lead
3d
multi
Ans. (d) Inorganic leadRef: K. Park 23rd ed. / 807-808* Insomnia is caused by organic lead poisoning.* Organic lead poisoning causes CNS side effects while Inorganic lead poisoning causes non-CNS side effects.Due to Organic Lead (CNS effects)Due to Inorganic Lead (Non-CNS effects)* Insomnia* Mental confusion* Headache*...
Social & Preventive Medicine
Occupational Health
b459479a-e311-4b3c-8b05-b528565bd212
Which of the following is MOST commonly affected in U.C
Cecum
Rectum
Sigmoid colon
Terminal leum
1b
single
Ans. is 'b' i.e., Rectum The most common site of involvement in Ulcerative colitis is the rectum. Ulcerative colitis (involvement is limited to the colon) Ulcerative colitis typically stas in the rectum and may progress with continuous lesions (no skip lesions) in a retrograde manner to involve the entire colon (Pancol...
Medicine
null
fddf5da2-d15e-4958-b1ca-64ad77fbcf2d
The differential diagnosis of lesion, histologically resembling giant cell tumour in the small bones of the hands or feet, includes all of the following except:
Aneursymal bone cyst
Fibrosarcoma
Osteosarcoma
Hyperparathyroidism
1b
multi
Ans. is 'b' i.e. Fibrosarcoma Histological differential diagnosis of Giant cell tumorGiant cell reparative granuloma (a benign reactive condition)Brown tumor of hyperparathyroidism Non-ossifying fibroma Benign fibrous histiocytoma Aneurysmal bone cyst Osteosarcoma with prominent giant cells.Metastatic ca with giant cel...
Orthopaedics
Giant Cell Tumor (GCT) or Osteoclastoma
707d2633-0524-40af-8fc7-59e7eed396cc
Antemoem Abrasions can be confused with?
Eczema
Ant bite marks
Chemical burn
Joule burn
1b
single
Postmoem ant bites on dead bodies may produce marks which simulate antemoem abrasions. Ref: Forensic Pathology By J.M. Di Maio, 2nd Edition, Page 196; Modi's Textbook of Medical Jurisprudence and Toxicology; Principles of Forensic Medicine and Toxicology By Rajesh Bardale, Page 174; Forensic Medicine and Toxicology By ...
Forensic Medicine
null
f339161b-3870-4f2b-bdd5-7d069376ca25
Pyomyositis is caused by which of the following?
Streptococcus aureus
Streptococcus pneumonia
Salmonella typhi
E. coli
0a
single
Pyomyositis is an acute bacterial infection of the skeletal muscle caused by Staphylococcus aureus. It may be primary or secondary to a penetrating injury or contiguous anatomic infection. It typically affects the major muscles of the lower extremity and the gluteal muscles. Patients usually presents with pain, tendern...
Microbiology
null
bd1ae929-0fee-40e5-8db6-9977a1fbcbbf
Increased intracranial tension is seen with:
Ketamine
Thiopentone
Halothane
Propofol
0a
single
ANSWER: (A) KetamineREF: Morgans clinical anesthesia 3rd edition page 141"Remember always Ketamine increases not only intracranial pressure but all the pressures of the body, like blood pressure, intraocular pressure, and intragastric pressure"Agents that increase intracranial pressure (ICP) can be remembered as Mnemon...
Anaesthesia
Anesthesia for Neurosurgery
36427da4-12bf-4cda-82db-726992f630d4
Which of the following is the most common functioning pancreatic islet cell tumour ?
Gastrinoma
Glucagonoma
Insulinoma
Vipoma
2c
single
null
Medicine
null
682c0763-848a-460b-a7fe-2119fed6a78d
Prophylaxis with Cotrimoxazole is recommended in the following situation except –
All symptomatic HIV infected children > 5 years of age irrespective of CD4
All HIV exposed infants till HIV infection can be ruled out
All HIV infected infants less than 1 year age irrespective of symptoms or CD4 counts
As secondary prophylaxis after initial treatment for pneumocystis carini pnetunonia
0a
multi
A) Cotrimoxazole prophylaxis in HIV exposed infant is recommended for :- All HIV exposed infants (started at 4-6 weeks of age and continued until HIV infection can be excluded). HIV exposed breast feeding children of any age (Prophylaxis should be continued until HIV infection can be excluded at least six weeks after ...
Pediatrics
null
0b6b272e-46a8-4625-8695-4d42260db2f8
True regarding foetal trunk movements in third trimester NOT RELATED - GYN
Increases towards term
Decreases towards term
Remain unchanged
None of the above
0a
multi
By term, the normal number of generalized movements is reduced as a result of cerebral maturation processes, rather than as a consequence of the decrease in the amniotic fluid volume.
Pharmacology
All India exam
849c3592-fff8-4ea4-b9cf-05560922830c
MELD score includes A/E
Sr. creatinine
Transaminase
Albumin
Alkaline phosphatase
0a
single
Ans. is 'a' i.e., Sr. creatinine The Model for End-stage Liver Disese (MELD) is a prospectively developed and validated chronic liver disease severity scoring system that uses a patient's laboratory values for - Li Serum bilirubin Serum creatinine The international normalized ratio (INR) for prothrombin time to predict...
Medicine
null
befcc088-1a09-4e7f-bab9-fc1856e9c8b7
Visual Hallucinations are commonly seen in :
Alzheimer's disease
Lewy body dementia
Frontotemporal dementia
Vascular dementia
2c
multi
Frontotemporal dementia is Characterized by Visual Hallucinations.
Psychiatry
null
30cff1c1-c249-4790-a5fa-c2e686464a6f
All of the following drugs are useful in detrusor instability except:
Solefenacin
Tolterodine
Flavoxate
Duloxetine
3d
multi
Ans. (D) Duloxetine(Ref: Principles of Pharmacology, 1/e p157, 159; KDT 8th/e p124)Anticholinergic drugs decrease the motility of urinary tract and thus may result in urinary retention (therefore contra-indicated in BHP).Dicyclomine, flavoxate and oxybutynin are useful for the treatment of urinary incontinence due to d...
Pharmacology
A.N.S.
70ca4793-b90a-4ef7-b607-5242d7684e81
Fatal level of ethanol in blood: NIMHAS 13
100-200 mg/dl
200-300 mg/dl
300-400 mg/dl
> 500 mg/dl
2c
single
Ans. 300-400 mg/dl
Medicine
null
86ac9994-66cd-4784-9a63-a0ec5d7eb076
Tylectomy literally means-
Excision of a lump
Excision of LN
Excision of breast
Excision of skin
0a
multi
Lumpectomy (Tylectomy): Surgical procedure designed to remove a discrete lump.
Surgery
null
d14c9af0-9def-4626-9371-3ec446e3371a
A 24-year old man falls on the ground when he is struck in the right temple by a baseball. While being driven to the hospital, he lapses into coma. He is unresponsive with the dilated right pupil when he reaches the emergency department. The most important step in initial management is :
Craniotomy
CT scan of the head
X-ray of the skull and cervical spine
Doppler ultrasound examination of the neck
0a
multi
Coma with a dilated pupil after a lucid interval following a head injury must be assumed to represent an epidural hematoma. Emergency evacuation of the clot without time-consuming studies is vital to restore cerebral function. CT scan is done with a patient in less critical condition.
Surgery
null
e08d6e54-9845-45a8-8b24-0717e6040d8e
Burkitt's Lymphoma is associated with which of the following viruses
EBV
HTLV-1
HHV- 8
Adenovirus
0a
single
Answer is A (t(8:14)) 'Demonstration of very high proliferative fraction and the presence of the t (8; 14) or one of its variants t (2; 8) or t(8:22) can be confirmatory of Burkitt's lymphoma /leukemia'
Medicine
null
89457faa-bd2c-444f-9569-b0f0e695bde9
Small fiber neuropathy is seen in?
HIV
Vitamin B12 deficiency
AIP
Cisplatin toxicity
0a
multi
Small unmyelinated peripheral nerve fibers, Categorized as C fibers, In skin and organs. Innervate the skin (somatic fibers) , Help to control autonomic function. Causes of Small Fiber Neuropathy: 1. Diabetes mellitus 2. Leprosy 3. Amyloidosis 4. Tangier's disease 5. Sjogren syndrome 6. HIV 7. Sarcoidosis
Medicine
Channelopathies and Neuropathies
ae559395-24dd-46ba-94ab-78dea599ab9c
All of the following are contents of Posterior Mediastinum except
Ascending Aoa
Hemiazygous vein
Thoracic duct
Oesophagus
0a
multi
Ascending Aoa is present in middle mediastinum.Contents of posterior mediastinum are1) Oesophagus 2) Aeries: Descending thoracic aoa and its branches.3) Veins: (i) Azygos vein, (ii) Hemiazygos vein, and (iii) Accessory hemiazygos vein.4) Nerves: (i) Vagus, (ii) Splanchnic nerves5) Lymph nodes and lymphatics (i) Posteri...
Anatomy
Thorax
b89cf064-d3fd-4822-9bef-c6ad7a97ef68
Transfer of DNA from one bacterium to other by a bacteriophage is known as
Formation
Conjugation
Transduction
Transcription
2c
single
Ans. c (Transduction). (Ref. Textbook of Microbiology by Anantanarayan, 6th/53)TRANSMISSION OF GENETIC MATERIAL IN BACTERIA IS BY:# Transformation:- Transfer of genetic information through agency of free DNA.# Transduction:- Transfer of a portion of DNA from one bacteria to another by transduction phase.- It is not con...
Microbiology
General
71fba271-3625-49f5-bfe6-f2215b3012eb
Pericardial effusion is best diagnosed by: September 2009
Chest X-ray
Echocardiography
ECG
Angiography
1b
single
Ans. B: Echocardiography Echocardiography is the imaging modality of choice for the diagnosis of pericardial effusion. Most impoantly, the contribution of pericardial effusion to overall cardiac enlargement and the relative roles of tamponade and myocardial dysfunction to altered hemodynamics can be evaluated with echo...
Medicine
null
fdb40ab1-e0c0-405d-a8f3-73f52b787f19
Which of the following opens directly into right atrium?
Anterior cardiac vein
Oblique vein
Middle cardiac vein
Great cardiac vein
0a
single
Following opens into right atrium -        Superior vena cava -        Inferior vena cava -        Coronary sinus -        Venae cordis minimae -        Anterior cardiac vein -        Right marginal vein
Anatomy
null
00c34add-87f1-499b-9d06-67d606f2d8c7
Which of the following is caused by congenital A-17 hydroxylase deficiency:
hypercalemia
Hyperkalemia
Hermaphroditism
Hypeension
3d
single
17 -hydroxylase (17 -OH) deficiency syndrome is a rare genetic disorder of steroid biosynthesis causing decreased production of glucocoicoids and sex steroids and increased synthesis of mineralocoicoid precursors. Reduced or absent levels of both gonadal and adrenal sex hormones result in sexual infantilism in 46, XX f...
Pediatrics
All India exam
4b1bbd47-a504-45a2-ab86-692b2ff9bdaf
Conductive hearing loss is seen in all of the following except:
Otosclerosis
Otitis media with effusion
Endolymphatic hydrops
Suppurative otitis media
2c
multi
Endolymphatic hydrops i.e menieres disease leads to SNHL and not conductive hearing loss.
ENT
null
564c25c2-e153-4b70-98e6-ea848af95093
Main aerial supply of the tonsil is from :
Facial aery
Ascending pharyngeal aery
Palatine aery
Palatine aery
0a
single
A i.e. Facial aery
Anatomy
null
7156da08-6147-44f2-b89a-f44a6fbe9489
Koenen's tumor associated with ?
Tuberous sclerosis
Neurofibromatosis
Psoriasis
Alopecia aerata
0a
single
Ans. is 'a' i.e., Tuberous sclerosis Koenen's periungual fibroma is seen in tuberous sclerosis
Skin
null