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135
1efd7aac-0ace-4bc6-9603-825aa2bfea05
Earliest symptom of glomus tumor is:
Pulsatile tinnitus
Deafness
Headache
Veigo
0a
single
Ans. A Pulsatile tinnitus "The two most common presenting symptoms of paraganglioma of temporal bone (Glomus tumor) are conductive hearing losso and pulsatile tinnnus" Hearing loss is conductive and slowly progressive Tinnitus is pulsatile and of swishing character", synchronous with pulse", and can be temporarily stop...
ENT
null
2b1c04e3-182f-46b4-850c-561c101eb895
Most common cause of insertional tendonitis of tendoachilles is -
Overuse
Improper shoe wear
Runners and jumpers
Steroid injections
0a
single
Achilles tendon injury Achilles tendon is the thickest and strongest tendon in the body and is also the one of the most commonly injured tendon in the body. The most common Achilles tendon injuries are :- Achilles tendinosis (formerly called Achilles tendonitis) Achilles tendon rupture Achilles tendinosis (Achilles...
Orthopaedics
null
d4af32dd-386b-4c10-b484-f109b2b4a7ad
Drug of choice of hypeension in pregnancy is ?
Methyldopa
Thiazide
Nifedipine
Labetalol
0a
single
Ans. is 'a' i.e., Methylopa o Methyldopa is DOC for hypeension in pregnancy. o Nifedipine is 2nd choice. o Hydralazine is DOC for hypeensive emergencies in pregnancy.
Pharmacology
null
8d3420cf-9433-4126-906b-f562d77ef7e2
Increased blood levels of cholesterol that are seen in hypothyroidism are most likely due to -
Decreased calorigenesis
Decreased production of LDL receptor in liver and the thus decreased clearance by liver
Decreased production of LDL receptor in the adipose tissue and increased release of cholesterol from adipose tissues
Increased breakdown of lipoproteins releasing cholesterol in circulation
1b
single
Ans- B Thyroid hormone increases the hepatic expression of LDL receptor. Hence in hypothyroidism there is reduction in hepatic LDL receptor So there is reduced clearance of LDL.
Unknown
null
1baea987-9c1c-4106-86f0-1a35cf304294
Sudden death, right sided heart failure (cor pulmonate or cardiovascular collapse occur when
Small pulmonary embolism
Massive pulmonary embolism
60% or more of pulmonary artery is obstructed with emboli
End artery obliteration
2c
multi
CONSEQUENCES OF PULMONARY EMBOLISM i) Sudden death. Massive pulmonary embolism(60% or moreof pulmonary artery) results in instantaneous death, without occurrence of chest pain or dyspnoea. However, if the death is somewhat delayed, the clinical features resemble myocardial infarction i.e. severe chest pain, dyspnoea an...
Pathology
null
9934b988-d862-48e7-a2d7-4253e0567231
Inferior olivary nucleus is present in
Base of pons
Midbrain, at level of superior colliculus
Midbrain, at level of inferior colliculus
Lateral medulla
3d
single
The inferior olivary nucleus, a cerebellar relay nucleus, is the most prominent nucleus in the lateral medulla. Coordinate signals from the spinal cord to the cerebellum to regulate motor coordination and learning. fig:- crossection at the level of medulla(upper pa)
Anatomy
Brainstem, cerebellum and ventricles
e9f2c377-749c-47b4-8baa-fc11457e5d43
Ovulation is seen after how many hours of the 'Peak' of the 'Up stroke' in this diagram here :
0-6 hours
10-12 hours
12-24 hours
24-36 hours
1b
single
From the onset of the LH surge, it takes 34-36 hours and from the peak it takes 10-12 hours to ovulate. The midcycle LH surge is responsible for a dramatic increase in local concentrations of prostaglandins and proteolytic enzymes in the follicle. These substances progressively weaken the follicular wall and ultimately...
Gynaecology & Obstetrics
Normal Menstruation, Abnormal Menstruation, Menopausal Physiology and forsight of conception
223beaa1-7b92-4e05-9835-4fb6974b35cd
The objective of the access cavity preparation is to gain direct access to
Pulp chamber
Canal orifice
Apical foramen
Middle third of the canal
2c
single
null
Dental
null
ecf5cf39-ae00-440d-a7bb-338897216678
Most radio resistant phase in cell cycle:
G1
Early S
Late S
G2
2c
single
Radiation energy is absorbed by tissue causing ionization or excitation, which are responsible for various biological effects. Susceptibility of various phases of cell cycle of radiation: G2M>M>G1> early S> late S phase Phase of cell cycle Comment G2M>G2 * Most sensitive to radiation End of S phase * Most resistant to ...
Surgery
Oncology
840dbf43-e03c-4050-bd33-ec56621f0aef
Boerhaave&;s syndrome is due to
Drug induced esophagus perforation
Corrosive injury
Spontaneous perforation
Gastro-esophageal reflux disease
2c
single
BOERHAAVE&;S syndrome is a tear in the lower third of oesophagus which occurs when a person vomits against a closed glottis, causing leaks into the mediastinum, pleural cavity, and peritoneum.site of perforation is about 2-10 cm of posterolateral pa of the lower oesophagus.investigations include chest Xray, MRI/CT, and...
Surgery
G.I.T
cb35cea0-5945-484b-b6f4-69c5847ca7aa
What is the effective antodote for acetaminophen overdose in a 28 year old suicidal patient?
N-Acetyl cysteine
N-Glycolamine
Penicillamine
Fomipezole
0a
single
N-acetylcysteine is used as an effective antidote for acetaminophen overdose. In acetaminophen overdose, N-acetylcysteine, a sulfhydryl-containing acetaminophen-specific antidote, replenishes hepatic stores of glutathione by acting as a glutathione surrogate, combining directly with reactive acetaminophen metabolites a...
Forensic Medicine
null
f98f13bb-883b-4565-a4b6-5e52a093010a
Green blue postmoem discoloration is seen in which poisoning ?
Cyanide
Carbon monoxide
Hydrogen sulphide
Hydrogen sulphide
2c
single
Ans. is 'd' i.e., Hydrogen sulphide
Forensic Medicine
null
01f4d86f-5e84-4ff0-87f6-98289e0f0f82
A 23-year-old woman with no other medical history was diagnosed with hypertension 6 months ago. She was initially treated with hydrochlorothiazide, followed by the addition of lisinopril, followed by a calcium channel blocker, but her blood pressure has not been well controlled. She assures the provider that she is tak...
Primary hyperaldosteronism (Conn syndrome)
Cushing syndrome
Congenital adrenal hyperplasia
Renal artery fibromuscular dysplasia
3d
multi
This patient is abnormally young to have essential hypertension, and the renal bruit is highly suggestive of a secondary cause of the condition: renal artery stenosis caused by fibromuscular dysplasia (FMD). FMD is more common in young females (85%-90% of patients are women). The exact etiology of the condition is unkn...
Medicine
Kidney
a154076b-f265-4ecd-ae4a-d78999a1862c
In co-arctation of aoa of the post -ductal type, all of the following blood vessels take pa in forming the collaterals execpt:
Axillary aery
Posterior intercostal aery
Suprascapular aery
Veebrall aery
3d
multi
D i.e. Veebral aery
Anatomy
null
570370c2-6601-4148-9210-1831933c8009
Jumping gene is:
Transposon
Cosmid
Episome
Plasmid
0a
single
Ans. is 'a' i.e., Transposon(Ref: Ananthanarayan, 9th/e, p. 63 and 8th/e, p. 64)Transposons are also known as jumping genes.Transposons are also known as jumping genes. They move between chromosomal DNA and extra chromosomal DNA within cell. They take part in drug resistance mechanism.
Microbiology
General
f270a031-2cae-44ca-bbe2-dd0f18893ce3
All are a complication of Typhoid ulcer, EXCEPT -
Perforation
Stricture
Haemorrhage
Sepsis
1b
multi
null
Pathology
null
cb1258c4-8cbd-492b-a84b-0019561acf32
Phenylbutyrate is used in the treatment of urea cycle disorders, because
It activates deficient enzymes
It maintains urine output
It acidifies the urine
It scavenges nitrogen.
3d
single
Phenylbutyrate and sodium benzoate act as ammonia(nitrogen) scavengers.
Biochemistry
null
f824bdbb-b30b-4c7c-97e5-ce1179ab9e46
In breast Ca 6 cm with fixed ipsilateral axillary lymphnode. The TNM staging is :
T3N2
T2N2
T4N2
T1N1
0a
single
null
Surgery
null
60d5558d-3a96-4d11-908c-1bcc942c754a
Removal of senescent RBC from circulation by spleen is called -
Culling
Pitting
Filtering
Phagocytosis
0a
multi
null
Surgery
null
b9a8b397-90bf-450b-ac91-c84ba44e58e7
For reduction of cholesterol, the best management includes:
Cholesterol restricted diet
High fiber diet
Diet with high unsaturated FA and low saturated FA
Cholesterol restricted diet, high fiber and diet with low saturated FA to unsaturated FA ratio
3d
single
D i.e. Cholesterol restricted diet, high fiber diet with low saturated FA to unsaturated FA ratio.
Biochemistry
null
04de54ce-da75-4040-97fb-a43662ee09ff
Increased sweat chloride is seen in all except –
Ectodermal dysplasia
Nephrogenic diabetes insipidus
Glucose 6 phosphatase deficiency
Obesity
3d
multi
Increased sweat chloride is seen in - Cystic fibrosis                                                                                                                       Malnutrition                                                                                                                         Pancreatitis  ...
Pediatrics
null
e810a3a8-c076-4f9c-a955-b9749afcea48
A 17 years old female patient came to emergency one & half hour after severe H2SO4 poisoning with features of hypotension, restlessness, next step is
Ryle's tube intubation
LV fluid sedation, monitoring
Gastric lavage
Antidote should be given
3d
multi
Ans. is 'd' i.e Antidote should be given Treatment plan of Sulphuric acid poisoning include:Avoid gastric lavage or emeticsStomach tubes are contraindicated.Alkaline carbonates & bicarbonates, which liberate C02 should not be used as they may cause gastric distention & rupture.Neutralization of the acid by milk of magn...
Forensic Medicine
Forensic Toxicology - Concepts, Statutes, Evidence, and Techniques
f510edaa-c420-4cfd-8ee8-ccdea6a8684c
Reversible cause of dementia -a) Post encephalitisb) Multi infarctc) Hydrocephalusd) Senile dementia
a
bc
ad
ac
3d
single
Chronic meningoencephalitis and hydrocephalus are reversible causes of dementia.
Psychiatry
null
bfdc9543-8d48-4bc2-ae4c-e60989a12720
Scurvy is due to deficiency of
Vitamin C
Vitamin A
Vitamin K
Vitamin E
0a
single
Deficiency of ascorbic acid results in scurvy, a disease characterized by sore and spongy gums, loose teeth, fragile blood vessels, swollen joints, and anemia. Many of the deficiency symptoms can be explained by a deficiency in the hydroxylation of collagen, resulting in defective connective tissue.Reference: Lippincot...
Biochemistry
vitamins
a01e24f6-5d3b-428f-b1a4-b2d86acf25b1
Congenital rubella syndrome may cause all the following except:
Patent ductus arteriosus
Spontaneous abortion
Sensory nerve deafness
None of the above
3d
multi
null
Medicine
null
4ba94a35-dd4c-4a99-a5b4-187eda13a1dd
True about cystic duct stump stone are A/E
Stone cause of postop pain
Re-cholecystectomy is the definite treatment of choice
ERCP is the investigation of choice to diagnose
Basket extraction is the Mx of choice
1b
multi
.Relative Contraindications of cholecystectomy includes, * End stage cirrhosis, ascites or poal hypeension. * Cholangitis: Cholecystectomy should be done after the control of cholangitis. * CBD stones: Here, initially ERCP and stone extraction is done from CBD, then laparoscopic cholecystectomy is done.Complications ca...
Surgery
G.I.T
554bc91b-8ebf-4ce1-a38c-919288522948
Tone of lower esophageal sphincter is increased by-
NO
VIP
Acetylcholine
Epinephrine
2c
single
Ans. is 'c' i.e., Acetylcholine Lower esophageal sphinctero Unlike the rest of the esophagus, the musculature of the gastroesophageal junction (lower esophageal sphincter: LES) is tonically active but relaxes on swallowing,o The tonic activity of the LES between meals prevents reflux of gastirc contents into the esopha...
Physiology
Physiology of Gastrointestinal Disorders
bc57be83-c378-49da-b75e-172ac4b39fed
LCAT is involved in
Transpo of dictory cholesterol
Transpo of dietory TGs
Reverse cholesterol transpo
None
2c
multi
Cholesterol Pool and Cholesterol MetabolismThe total body cholesterol content varies from 130-150 grams. LDL (low-density lipoprotein) transpos cholesterol from the liver to the peripheral tissues and HDL (high-density lipoprotein) transpos cholesterol from tissues to liver. Cells of extrahepatic tissues take up choles...
Biochemistry
Metabolism of lipid
a50b09f1-ca5d-49df-a9e2-3de768ffc30e
Which of the following is used for treatment of Alzheimer's disease?
Donepezil
Rivastigmine
Galantamine
All of the above
3d
multi
Tacrine (tetrahydroaminoacridine, THA), a long-acting cholinesterase inhibitor and muscarinic modulator, was the first drug shown to have any benefit in Alzheimer's disease. Because of its hepatic toxicity, tacrine has been almost completely replaced in clinical use by newer cholinesterase inhibitors: donepezil, rivast...
Psychiatry
null
2babcd35-7be3-4ff5-b8b9-ae8b41c300da
Exchange of sodium for potassium in the distal convoluted tubule is regulated primarily by:
Angiotensin 1
Aldosterone
Antidiuretic hormone (ADH)
Androstenedione
1b
single
The distal convoluted tubule in the kidney coex functions to reabsorb sodium and secrete potassium. This is regulated by the adrenal hormone aldosterone as stimulated by angiotensin II which will increase reabsorption of sodium and secrete potassium. The distal convoluted tubule also functions in the continuation of bi...
Physiology
null
6dde832a-651e-46d7-9c4b-4ebc4aa38c91
Which of the following is used for antibiotic sensitivity testing
Thayer main medium
Mueller hinton agar
Chocolate agar
None of the above
1b
multi
Muller-Hinton agar is a microbiological growth medium that is commonly used for antibiotic susceptibility testing. It is also used to isolate and maintain Neisseria and Moraxella species Ref ananthnarayana and panikers microbiology textbook 8/e
Microbiology
general microbiology
798c45ab-90f9-415e-ae9f-78b939f731a0
Chymotrypsinogen is a:
Transaminase
Carboxypeptidase
Clot lysing protein
Zymogen
3d
single
Ans. d. Zymogen: (Ref: Lippincott 4/e p64, 443, 248-49; Harper 29/e p89, 519, 651-53)Chymotrypsinogen or prochymotrypsin is a proprotein, proenzyme or zymogen."Chymotrypsinogen or prochymotrypsin is a proprotein, proenzyme or zymogen. Trypsin can then activate chymotrypsinogen to chymotrypsin, proelastase to elastase. ...
Biochemistry
Miscellaneous (Enzymes)
171b2ebf-8c3e-4c5a-b7b9-f9e5ef540e69
Tumorlysis syndrome is associated with all of the following laboratory features except -
Hyperkalemia
Hypercalcemia
Hyperuricemia
Hyperphosphatemia
1b
multi
null
Medicine
null
c334f24c-dcc8-4702-9ee5-e0f68d7efdfb
Which of the following is a stimulus for closure of ductus arteriosus?
Increased O2 tension
Hypoxia
Prematurity
Hypercapnia
0a
single
a. Increased O2 tension(Ref: Nelson's 20/e p 2162)In the course of several days after birth, the high arterial Po2 constricts and eventually closes the ductus arteriosus, which eventually becomes the ligamentum arteriosum
Pediatrics
C.V.S.
80fae05d-a4f1-49cb-8c83-58caa7c5ce12
Laplace's law for cylinder?
P = T/R PT ( 1/rl - l/r2)
P = 2T/R
P = T/R
None of the above
2c
multi
Ans. c (P = T/R) (Ref. Ganong Physiology 22nd/584)LAPLACE'S LAW states that wall tension (T) is proportional to the product of intraventricular pressure (P) and ventricular radius (r).-----------------------------T. p.r# P = 2T/R.... IN A SPHERE (BECAUSE R1=R2).# P = T/r.... In a Cylinder like blood vessel (one radius ...
Physiology
Heart, Circulation, and Blood
22535dc3-c846-42f8-87bf-62fd133a2b06
Myoclonus in children is best treated by:
Clonazepam
Sodium Valproate
Phenobarbitone
Ethosuccimide
1b
single
Myoclonic and atonic seizures-control is often incomplete, but valproate is the drug of choice. Myoclonic Seizures. Myoclonic seizures are characterized by brief, jerking spasms of a muscle or muscle group. They often occur with atonic seizures, which cause sudden muscle limpness. The word "myoclonic" combines the Gree...
Pharmacology
Central Nervous system
f53b3d5e-9d2a-4697-be1e-bfedf89275b3
Transplantation of which one of the following organs is most often associated with hyper acute rejection?
Heart
Kidney
Lungs
Liver
1b
single
Ans. (b) KidneyRef: Bailey 26th edition, Page 1409* Hyperacute rejection is most common in Kidney* Hyperacute rejection is very rare in liver
Surgery
Transplantation
4b104999-eebb-4d32-8cb9-b7a3dccfeac7
Which of the following is not a feature of sickle cell disease?
Autosplenectomy
Heterozygous individuals are at increased risk of Plasmodium falciparum infection
Ischemic tissue damage
Hydroxyurea is used as a therapeutic agent
1b
single
Sickle cell disease Caused by missense mutation in the b-globin gene that leads to the replacement of a charged glutamate residue with a hydrophobic valine residue. Mutation promotes the polymerization of deoxygenated hemoglobin, leading to red cell distoion (sickling), hemolytic anemia, microvascular obstruction, and ...
Pathology
Megaloblastic Anemia
d606a2c8-8704-4b2e-b538-b9072d562a8a
Maximum risk of death is seen in which week of the neonatal period?
First week
Second week
Third week
Fouh week
0a
single
The major causes of neonatal moality are prematurity/low bihweight (LBW) and congenital anomalies.Moality is highest during the 1st 24 hr after bih.Neonatal moality accounts for about two-thirds of all infant deaths (deaths before 1 yr of age).(Refer: Nelson, Chapter 93; pg no. 789)
Pediatrics
All India exam
562f0008-129a-488b-bca2-f81e21354d19
Rose spot is associated with?
Typhoid fever
Malaria
Scarlet fever
Wilson disease
0a
single
Enteric fever: In 25% of cases, a macular or maculopapular rash (rose spots) may be visible around the 7th-10th day of the illness These lesions may be difficult to see in dark-skinned children.
Pediatrics
Impoant Bacterial Diseases in Children
3b795307-511f-4e87-a604-eb8d7f974d77
Koener's tumor are seen in?
Tuberous sclerosis
Neurofibromatosis
VHL
NF
0a
single
Ans. (a) Tuberous sclerosis(Ref: Robbins 9th/pg 516)Ungual fibromas or Koenen's tumors are angiofibromas which occur in the lateral nail groove, along the proximal nail fold or under the nail. They are seen in Tuberous Sclerosis
Pathology
Central Nervous System
fd5a8e0f-909c-41fa-bcdb-4e5b340da0b4
When to do surgery in pancreatic ascites?
Symptomatic
Recurrent ascites following abdominal drainage
Not responding to medical therapy
Leak from the stented duct
1b
single
PANCREATIC ASCITES: MANAGEMENT Pancreatic ascites occurs from a pancreatic duct disruption or from a leaking pseudocyst. High amylase levels are found in the ascitic fluid. Initial treatment: Non operative (elimination of enteral feeding, institution of nasogastric drainage, and administration of somatostatin) Repeat p...
Surgery
Pancreas
4dc22fe6-55b1-4e6d-9609-5a758a150adf
Hypertension with hypokalemia is found in
Bartter syndrome
Gitelman's syndrome
Liddle's syndrome
All the above
2c
multi
Hypertension in Bartter's & Gitelman's.
Medicine
null
c164e337-cf93-42c6-9ed0-dee0dde98067
Spiral field defect is a feature of
Hysterical amblyopia
Amblyopia exanopsia
Toxic amblyopia
Malingering
0a
single
HYSTERICAL BLINDNESS It is a form of psychoneurosis, commonly seen in attention-seeking personalities, especially females. It is characterised by sudden bilateral loss of vision.There may be associated blepharospasm and lacrimation. Visual fields are concentrically contracted. One can commonly find spiral fields as the...
Ophthalmology
Neuro-ophthalmology
11f34dee-77fb-42a0-87f5-88e27f39c1ce
Most common organism causing meningitis in a 1 year old child -
Streptococcus pneumoniae
H. influenza
Listeria
Neisseria meningitidis
0a
single
Ans. is 'a' i.e., Streptococcus pneumoniae
Pediatrics
null
4458e85f-94c5-4130-807e-8c767c2745b7
All of the statements are true about FLUORO QUINOLONES, except -
Suspected of having teratogenic potential
Ahropathy of limb-in children may occur
Increase theophylline toxicity
Increase neuromuscular blocking action
3d
multi
Ans. is 'd' i.e., Increased Neuromuscular blocking action Fluoroquinolones are contraindicated in children < 18 years of age, because of evidence in animals of cailage damage in developing joints. o They are contraindicated in pregnancy because of concerm for the developing fetus (teratogenicity) o Fluoroquinolones are...
Pharmacology
null
b8ac8b18-5a2c-4bc8-a552-f8a054f1a5c1
All are true about pouchitis except:
Probiotics have shown promising response
Cause may be related to mucosal ischemia
Most commonly seen in ulcerative colitis surgeries
Episodes of pouchitis will not respond to antibiotics
3d
multi
Ans. (d) Episodes of pouchitis will not respond to antibioticsTreatment protocol for pouchitis:* 1st line: Ciplox + Metronidazole* 2nd line: Probiotics added* 3rd line: Add ASA compounds* 4th line: Pouchectomy and permanent ileostomy
Surgery
Small & Large Intestine
1abbff0c-6488-4348-b194-a7132833d1e0
Most common anorectal fistula:
Inter sphincteric
Trans sphincteric
Supra sphincteric
Extra sphincteric
0a
single
PARK'S CLASSIFICATION Type 1 Inter- sphincteric (MC) Type 2 Trans- sphincteric Type3 Supra- sphincteric Type4 Extra- sphincteric Investigations - First investigation - Fistulogram - IOC- MRI Treatment High morbidity * Fistulotomy -Incision over fistula tract it * Fistulectomy- Excision of fistula tract. * SETON * VAAFT...
Surgery
Rectum and anal canal
6080775c-039b-4c34-bb52-fac8a9770639
All are Phenolic disinfectant except-
Dettol
Cresol
Lysol
Carbolic acid
0a
multi
Phenol (carbolic acid) is a powerful microbicidal substance. This and other phenolic disinfectant derived from coal tar are widely used as a disinfectant for various purposes in hospitals. Lysol and Cresol are active against a wide range of organisms. They are not readily inactivated by the presence of organic matter a...
Microbiology
general microbiology
780d845b-276c-4af7-b7d9-568b767f93d6
"Indican" is a metabolite of
Histidine
Tryptophan
Tyrosine
Valine
1b
single
Indian is a major excretory product in the metabolism of tryptophanRef: DM Vasudevan - Textbook of Biochemistry, 7th edition, page no: 242, fig 18.11
Biochemistry
Metabolism of protein and amino acid
fc0b4c3e-0b4c-460f-bc31-1eb2420a62b4
Hanging is established by :
Fracture of hyoid cailage
Fracture of thyroid cailage
Staining of saliva
All
2c
multi
C i.e. Staining of saliva
Forensic Medicine
null
7cc235e9-2e4c-48d2-9774-b53d794eb598
Ivermectin is used in all except-
Ascariasis
Malaria
Filariasis
Onchocerciasis
1b
multi
Ivermectin is a recently developed macrocyclic lactone that has widespread antiparasitic activity. A series of clinical trials has shown that ivermectin is safe and effective in the treatment of human infection with Onchocerca volvulus. Its use promises to revolutionise the treatment of onchocerciasis. Ivermectin for t...
Medicine
Infection
bbbd60ab-bfdb-4d46-950c-535352cac34c
For the past week, a 65-year-old woman has been treated for a severe infection with broad-spectrum antibiotics, and she had recovered well. Over the past day, however, she has developed foul-smelling, voluminous, greenish, watery diarrhea, as well as abdominal pain and fever. She is diagnosed with pseudomembranous coli...
Aggregation of bacterial colonies on the lumen, forming pseudomembranes
Bacterial release of exotoxin, inducing necrosis of the mucosa
Physical invasion of bacteria into the superficial mucosa, leading to pseudomembrane formation
Selective killing of C. difficile bacteria by antibiotics
1b
single
- Pseudomembranous colitiis Overgrowth of C. difficile following antibiotic therapy d/t destruction of normal intestinal flora. Aka Antibiotic-associated colitis / Antibiotic-associated diarrhea Produces exotoxin that induces necrosis of superficial mucosa, -Pseudomembrane formation. Bacteria itself does not invade the...
Pathology
Small Intestine Malabsorption disorders
cdc72949-ccff-4be1-80d0-58e0c3cb7740
Pars planitis is also known as
Intermediate uveitis
Anterior uveitis
Posterir uveitis
Pan uveitis
0a
single
Ans. a (Intermediate uveitis) (Ref. Parson's 19th/pg. 360 & Basak's Ophthalmology, 2nd /p. 151; Q. 157 of MH-2007)INTERMEDIATE UVEITIS (PARS PLANITIS)# Thought to be immunological reaction# 2nd to 4th decade# Usually trilateral (80%)# Floaters & blurring of vision# Snow-ball vitreous opacities# Snow-bank exudates over ...
Ophthalmology
Uveal Tract
5d66d353-ced9-45fd-87ac-fd6245cace9c
Decreased glucose concentration in hepatic cells triggers all of the following except –
Increased glucagon levels in blood
Activation of fructose-2,6-biphosphatase
Inhibition of phosphofructokinase-2
Increased fructose-2,6-biphosphate levels
3d
multi
Decreased glucose level leads to increased levels of glucagon . Glucagon inhibits activity of PFK-2, and stimulates the activity of Fructose 2,6 biphosphatase . Activation of fructose-2,6-biphosphatase leads to decreased level of fructose-2,6-biphosphate levels . Ref: Harper’s illustrated Biochemistry 27th ed.
Unknown
null
6c41b9df-d78e-4d22-9f41-944f11f0f5b7
Which of the following is not a prominent risk factor for stroke?
High blood pressure
Elevated cholesterol
Smoking
Alcohol
3d
single
Alcohol is not a prominent risk factor for stroke or hea disease but is for cancer and motor vehicle accidents. Ref: Park's textbook of Preventive and Social Medicine, 21stedition, page-37
Social & Preventive Medicine
null
6678f45f-185c-4fb4-9141-f7bdd149955c
Inflammation in the airways can be reduced by:
Fluticasone
Budesonide
Theophylline
Salbutamol
0a
single
fluticasone an example of inhaled steroid coicosteroids suppress bronchial inflammation by stimulating lipocoin production and inhibiting phospholipase A2 after binding to intracellular receptors ESSENTIALS OF MEDICAL PHARMACOLOGY SEVENTH EDITION KD TRIPATHI PG NO.230
Pharmacology
Respiratory system
ebf01456-efac-4fcc-8f2f-6712b5acaaf1
In Gonorrhoea -- which is not a presenting feature?
Discharge
dysuria
Hematuria
Reddened lips of vulva and vagina
2c
single
Symptoms dysuria vaginal discharge excessive irritant acute unilateral pain and swelling over labia rectal discomfo labia look swollen and inflamed D.C.DUTTA'S TEXTBOOK OF GYNECOLOGY,Pg no:147,6th edition
Gynaecology & Obstetrics
Infections of the genital tract
f0bb2de5-f418-4092-ab01-1279b7ef089d
Enchondral ossification is/are seen in:
Long bones
Flat bones of skull
Clavicle
Mandible
0a
single
A i.e. Long bones Endochondral ossification is seen in long bones, veebrae, pelvis, and bones of base of skullQ; whereas intramembranous ossification occurs in skull vault, flat bones of skull, maxilla, majority of mandible and clavicleQ
Anatomy
null
88af1f5a-6ef6-4e36-ba39-ab931ec66a37
Which of the following is not associated with active chronic hepatitis B?
HBsAg
IgM anti-HBcAg
HBeAg
Anti-HBsAg
1b
single
Diagnostic tests for ch. hepatitis B is FIBsAg, lgG anti-HBc, HBcAg, HBv DNA. IgM anti-HBc is present in acute hepatitis B infections which disappears gradually will the appearance of IgG antiHBc. Ref - Harrison's internal medicine 20e pg 2349 t
Medicine
Infection
ce6c0cd1-7977-4493-bad7-efa6436ba805
The number of bacteria on skin are -
10l- 102
102- 105
105-1010
1010
3d
single
Ans. is 'd' i.e., >1010 It has been calculated that a human adult has about 1012 bacteria on the skin, 1010 in the mouth and 1014 in thegastrointestinal tract. ---------Textbook of bacteriology
Microbiology
Misc.
57dc6d4b-3b1e-48db-98fd-e2707b45b11e
For a dental hand instrument with a formula of 10-8.5-8-14, the number 10 refers to ________.
The width of the blade in tenths of a millimeter
The primary cutting edge angle in centigrades
The blade length in millimeters
The blade angle in centigrades
0a
single
The first number is the width of the blade or primary cutting edge in tenths of a millimeter (0.1  mm).  The second number of a four-number code indicates the primary cutting edge angle, measured  from a line parallel to the long axis of the instrument handle in clockwise centigrades. The angle is  expressed as a percen...
Dental
null
f5460c5c-cc56-4bf0-8b6e-0fdc3792ed03
According to MTP Act, 2 doctor's opinion is required when pregnancy is :
10 weeks
6 weeks
> 12 weeks
> 20 weeks
2c
single
Ans. is c i.e. > 12 weeks Medical termination of Pregnancy act passed in 1971deg is an impoant topic. Many questions are asked on this topic. I am giving MTP Act in detail - Do go through it. THE MEDICAL TERMINATION OF PREGNANCY ACT, 1971 In India. the MTP act was passed in August 1971 and came into effect from April 1...
Gynaecology & Obstetrics
null
f893efb2-7204-472c-9a0a-d63c763fd3ab
According to Body weight method what is the amount of IV fluid required in first 24 hours for a child weighing 14 kg?
1000
1200
1400
Any of the above
1b
multi
Ans. b (1200) (Ref. Nelson Textbook of Pediatrics, 17th ed. Table 46-1)BODY WEIGHT METHOD FOR CALCULATING MAINTENANCE FLUID VOLUMEBody WeightFluid per Day0-10 kg100 mL/kg11-20 kg1,000 mL + 50 mL/kg for each kg > 10 kg> 20 kg1,500 mL + 20 mL/kg for each kg > 10 kg** The maximum total fluid per day is normally 2,400 mL.M...
Pediatrics
Fluid & Electrolyte
ed09eab8-e309-4229-9b9d-ebcb59650b8a
A 55yr old women diagnosed to be Ca cervix stage 2B advised for chemo radiation Which of the following is true statement
small bowel is most radio resistant
small blood vessels are most radio resistant
rapidly proliferating cells are most radio resistant
dose intensity of radiation is inversely propoional to the square of distance of the source
3d
multi
REF : SHAW GYNECOLOGY
Gynaecology & Obstetrics
All India exam
9fbc781a-d19f-46bc-94ac-edc045013047
Fatal dose of methanol is?
15 ml
150 ml
500 ml
650 ml
1b
single
Ans. is 'b' i.e., 150 ml * Methanol is highly toxic alcohol. It is metabolized to formaldehyde (by alcohol dehydrogenase) and formic acid (by acetaldehyde dehydrogenase). It can be present in contaminated country liquor used to denature ethanol.* It is the accumulation of formic acid which causes toxic effects in metha...
Forensic Medicine
Toxicology
25736212-c5b4-4920-8e33-c1b80716a9f9
Non-sterile hypopyon is seen in -
Pneumococcus infection
Pseudomonas infection
Fungal infection
Gonococcal infection
2c
single
Ans. is 'c' i.e., Fungal infection o Hypopyon refers to accumulation ofpolymorphonuclear leucocytes in the lower angle of anterior chamber. Many pyogenic organisms (Staphylococcus, streptococci, gonococci, Moraxella) and fungi may produce hypopyon but by far the most dangerous are pseudomonas pyogenea and pneumococcus....
Ophthalmology
Inflammations of the Cornea
a93cf1bd-dcf3-4782-babf-52b0e4651318
The most likely precursor to bronchiectasis is
Tuberculosis
Carcinoma
Bronchial adenoma
Bronchopneumonia
3d
single
BronchiectasisAbnormal and permanent dilatation of bronchi.The bronchial dilatation of bronchiectasis of is associated with destructive and inflammatory changes in the walls of medium-sized airways, often at the level of segmental or subsegmental bronchi.Types of bronchiectasisCylindrical bronchiectasis Varicose bronch...
Anatomy
All India exam
6933d755-96fb-4771-8be8-ee4d3d9b1b9f
What is the BMI for obese person: March 2010
Less than 18.5
Less than 18.5
25-29.9
More than 30
3d
single
Ans. D: More than 30
Physiology
null
fb0bf5fc-d85f-4cbc-a48e-ac2c728f5866
Classical triad of symptoms of depression includes all except ?
Depressed mood
Slowed thinking
Distractibility
Psychomotor retardation
2c
multi
Ans. is 'c' i.e., Distractibility Clinical features of depression The classical triad of depression is depressed mood, psychomotor retardation, and slowed-down thinking. Mood : Mood is characteriztically low and sad. There is loss of interest and pleasure in almost all activities, which result in social withdrawal, avo...
Psychiatry
null
357fdb27-87e9-4ca8-81ab-fe2355e723d5
Munchausen's syndrome by proxy involves:
Drug abuse
Toxin mediated neuropsychiatric disorder
Illness caused by caregiver
All of the above
2c
multi
Munchausen syndrome by proxy This rare disorder is where a parent or caregiver repeatedly fabricates an illness or disability in a child they are looking after, for the benefit of themselves. The adult involved is most frequently the child's mother, but not always. There are several impoant aspects to this condition Th...
Psychiatry
Schizophrenia Spectrum and Other Psychotic Disorders
2949130e-edee-4fcb-98ef-315340ac86ba
Most common cause of neuropathic joint:
Diabetes
Amyloidosis
Syphilis
Leprosy
0a
single
Ans: a (Diabetes) Ref: Harrison, 16th ed, p. 2060; 17th ed, p. 2180Most common cause of neuropathic joint is diabetesNeuropathic joint (Charcot joint)It is a progressive destructive arthritis associated with loss of pain sensation, proprioception or both.Clinical featuresIt begins as a single joint and then progresses ...
Medicine
Immunology and Rheumatology
5c1b49eb-b61c-4464-b56a-982be32cb87b
A 11 month old child presents with complaints of respiratory distress. On examination there is bilateral crepitation and wheezing. Which of the following is the most likely cause -
Pneumonia
Adenovirus
Respiratory synchytial virus
Rhinovirus
2c
single
Ans. is 'c' i.e., Respiratory synchytial virus o The child presenting with respiratory distress and bilateral crepitations and wheezing, we have to suspect brochiolitis.
Pediatrics
null
60f3b070-f393-4a43-9dbd-d78a4a97839e
After thyroidectomy for medullary carcinoma of thyroid, which is impoant for determining recurrence of a tumour?
Thyroglobulin
TSH
Calcitonin
Thyroxine
2c
single
High levels of serum calcitonin and carcinoembryonic antigen are produced by many medullary tumours, which should be tested for in suspected cases.Calcitonin levels fall after resection and rise again with recurrence, making it a valuable tumour marker in the follow-up of patients with this disease.Ref: Bailey and Love...
Surgery
Endocrinology and breast
7c1173f5-c1a5-4ef3-b468-c92881092253
A 2 years old child is brought to the emergency with history of fever and vomiting. On examination he has neck rigidity. The CSF examination shows polymorphs more that 2000/ml protein 100 mg/dl and glucose 10mg/dl. The Gram stain shows the presence of Gram negative coccobacilli. The culture shows growth of bacteria onl...
Neisseria meningitidis
Haemophilus influenzae
Branhamella catarrhalis
Legionella pneumophila
1b
single
null
Microbiology
null
3e10afe5-f8e9-470e-a549-b93f182624b9
A lady presented to your with a history of recurent early pregnancy loss. What are the investigation to be ordered:
VDRL
Toxoplasma serology
Hemogram/Blood grouping
Rubella screening
2c
single
Ans. is C i.e. Hemogram /blood grouping? As discussed in previous answer? Complete blood counts along with platelet count are done in case of recurrent pregnancy loss. VDRL-To test for syphilis Rubella-virus screening are not done because as discussed earlier, infections rarely lead to recurrent Toxoplasma serology pre...
Gynaecology & Obstetrics
null
61675305-3efd-4d04-8337-9b647574cfa6
"Gate" cells in the hea are:
Cells in SA node
Cells in AV node
Cells in his bundle
Cells in Purkinje fibers
3d
single
Purkinje fibers at the apex, where impulse is passed on from Purkinje fibers to ventricular muscle, are the so-called "gate cells".
Physiology
Conducting System of Hea
77bcc3c0-fb26-434d-ad8b-9819bc518c46
At what age (in years) does-a child attain a height of 100 cms?
2
3
4
5
2c
single
Ans. (c) 4 yearsRef: OP Ghai 8th ed./13* Length of Indian baby at birth=50cm* Length at 1 year=75cm* Length at 4 1/2 years= 100cm* Subsequently 5-6 cm/year* Pubertal growth spurt=6-8cm/year
Pediatrics
Assessment of Growth
e5f25259-40a0-46b3-a25b-c216809a3262
Clinical features of pseudocyesis are all of the following except :
Quickening
Enlargement of uterus
Amenorrhea
False labor
1b
multi
Enlargement of uterus
Gynaecology & Obstetrics
null
85ed2c91-8dbe-4f24-a54c-58760c25f7cf
Stapedius muscle is supplied by.....nerve:
Facial
Vagus
Glossopharyngeal
Trochlear
0a
single
A i.e. Facial nerve
Anatomy
null
7056c115-c69a-4509-9463-cb821c2a47a8
Most common complication of mid shaft humerus fracture is -
Radial nerve palsy
Median nerve palsy
Nonunion
Malunion
0a
single
Ans. is 'a' i.e., Radial nerve palsy Complications of humerus shaft fractureNerve injury : - Radial nerve is the most commonly injured nerve in fracture shaft humerus. It is particularly common in oblique fractures at the junction of middle and distal third of the bone (Holstein- Lews fracture).Vascular injury : - Brac...
Orthopaedics
Humerus Fractures
5b4dc106-e2e8-40b2-aaff-5efe31f4fed3
The tumor suppressor gene P53 induces cell arrest at-
G2 - M phase
S G2 phase
G1 - S phase
Go - phase
2c
single
Harshmohan textbook of pathology 7th edition. In blocking mitotic activity p53 inhibits the cyclins and CDKs and prevent the cell to enter G1 phase transientally. This breaking time in the cell cycle is utilised by the cell to repair the DNA damage..
Pathology
General pathology
0799ebd4-a3f4-49fd-9c2c-93880fffcc2f
Which of the following can delivery 100% oxygen
Venturi mask
Anesthetic face mask
Hudson mask
Non - rebreather face mask
1b
single
Devices used foroxygen therapy Performance of these devices can be described according to 1. Themaximum oxygen concentrationachievable to be delivered to the patient, and the reliability/ variability with which the devices do that. Looking at the reliability and variability of oxygen delivery to the patient we can divi...
Anaesthesia
Airway
af90713f-ef43-4591-ba9c-85b1955087de
The following are characteristic of autism, EXCEPT:
Onset after 6 years of age
Repetitive behavior
Delayed language development
Severe deficit in social interaction
0a
multi
The onset of autistic disorder always occurs before age 3, at two peak periods. Autistic disorders are characterized by the triad of impaired social interaction, communication and imagination. These are associated with rigid repetitive pattern of behaviour. Ref: Essential Pediatrics By O P Ghai, 6th Edition, Page 65; A...
Psychiatry
null
2496161d-375c-4c65-8779-d9a40cb1e0bb
Epley's test is used for which of the following conditions?
Benign paroxysmal positional veigo
Basilar migraine
Ohostatic hypotension
Thoracic outlet syndrome
0a
single
Benign paroxysmal positional veigo (BPPV) is characterised by veigo when the head is placed in a ceain critical position. There is no hearing loss or other neurologic symptoms. Disease is caused by a disorder of posterior semicircular canal. The condition can be treated by performing Epley's manoeuvre. The principle of...
ENT
null
17e2381b-2573-4852-a8b9-b3ed20f349ce
Epidemic relapsing fever is transmitted by?
Louse
Soft tick
Hard tick
Rat flea
0a
single
ANSWER: (A) LouseREF: Park textbook of preventive and social medicine 20th edition page 684 "Epidemic relapsing fever is transmitted by Louse"Always remember:Epidemic typhus Endemic typhus Epidemic relapsing fever Endemic relapsing feverLouse Rat flea Louse Soft tickDiseases transmitted by louse can be remembered as "P...
Social & Preventive Medicine
Environment and Health
e6a81818-8983-44cd-bdcb-0a8c42c67086
Isolation period of Hepatitis A after the onset of jaundice is:
1 week
2 week
3 week
4 week
0a
single
Isolation: The period of isolation is determined by the duration of communicability of the disease and the effect of chemotherapy on infectivity. Period of infectivity: the risk of transmitting Hepatitis A virus is greatest from 2 weeks before to 1 week after the onset of jaundice. Thus isolation of the patient 2 weeks...
Microbiology
null
8bc9723e-6d0e-4db8-88ac-b7a70b89d885
MC presentation of Hodgkin's disease: March 2013
Weight loss
Palpable lymphadenopathy
Fever
Night sweats
1b
single
Ans. B i.e. Palpable lymphadenopathy Hodgkins lymphoma Malignant cells of Hodgkin's disease are: Reed Sternberg cells/ RS RS cells are positive for: -- CD15 and -- CD30 Subtype of Hodgkin's disease, which is NOT positive for CD15 and CD30: Lymphocytic predominant Lacunar cells are seen in: Nodular sclerosis type of lym...
Medicine
null
1ee59766-772f-4e95-8f33-e7209abe451a
A 42-year-old female is admitted to the hospital with dyspnea. Imaging reveals severe mitral valve regurgitation. Which of the following structures prevents regurgitation of the mitral valve cusps into the left atrium during systole?
Crista terminalis
Crista supraventricularis
Pectinate muscles
Chordae tendineae
3d
single
The chordae tendineae are fibrous cords that connect papillary muscles to valve leaflets. The restraint provided by these cords on the valve leaflets prevents the prolapse of the mitral valve cusps into the left atrium. The crista terminalis is a ridge that runs from the opening of the inferior vena cava to the superio...
Anatomy
Thorax
479500f5-f2a3-480d-810c-cde48dce8139
True about Erythema Marginatum in Acute Rheumatic fever is:
Pruiritic
Commonly involves face
Common manifestation of Acute Rheumatic fever
Usually associated with carditis
3d
multi
Answer is D (usually associated with carditis) Erythema marginatum and sub cutaneous nodules are usually associated with carditis manifestation Erythema marginatum is a rare (< 3%) manifestation of Acute Rheumatic fever. Rash is charachteristically non pruiritic and almost never involves the face.
Medicine
null
168c379a-1ae2-4c75-befb-f6f5ba6f2661
Pathognomic finding of rabies is: March 2012
Obliterative endaeritis
Microglial nodules
Neuronophagia
Negri bodies
3d
single
Ans: D i.e. Negri bodiesPathologic changes and associated conditionsIn tuberculosis, aeries running through the subarachnoid space may show obliterative endaeritis with inflammatory infiltrates in their walls and marked intimal thickeningHIV encephalitis is best characterized microscopically as a chronic inflammatory r...
Pathology
null
49c25122-3125-4bd9-b82f-f76f52f788a9
A 64-year-old man presents with symptoms of difficulty swallowing and weight loss of 10 lb. He has no prior history of heartburn, stomach ulcers, or difficulty swallowing. He smokes one pack a day for the past 45 years and drinks approximately 5 oz of alcohol a day. He is thin appearing, there are no oral lesions, and ...
adenocarcinoma of esophagus
esophageal web
achalasia
squamous cell carcinoma of esophagus
3d
multi
The history of weight loss and dysphagia suggests carcinoma of the esophagus, and squamous cell carcinoma is a disease that occurs in older men who drink and smoke heavily. Smoking and or excessive drinking are considered etiologic factors in the development of squamous cell carcinoma. Adenocarcinomas arise within dysp...
Medicine
Oncology
92519ea0-6846-458c-a81e-70d2396646f4
Monoamniotic monochorionic twins develop if division occurs after:
24 hrs
1-3 days
8 days
14 days
2c
single
Ans: c (8 days) Ref: Dutta, 6th ed, p. 203If the division occurs after 8th day of fertilization, when the amniotic cavity has already formed, a monoamniotic--monochorionic twins developsTwins:There are two different types of twins -- dizygotic and monozygotic(i) Biovular - (Dizygotic/ Fraternal twins) - Diamniotic dich...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
df96db51-b0bd-457f-ab91-81b876360bd9
A baby can follows an object with 180°, can hold neck, can sit with support but can not sit without support.The age of the baby is – a) 1 monthb) 3 monthsc) 5 monthsd) 6 monthse) 9 months
cd
bc
bd
ac
0a
single
A child follows object upto 180° by 3 months, ---- Meharban Singh 3'.d/e 67. Neck holding develops by 3 months. A child can sit with support by 5 months and can sit without support by 8 months. So, the age of this child is between 5-8 months, which may be 5 months (option c) or 6 months (option d) or 7 months.
Pediatrics
null
ecbd496a-6f73-48de-9c6e-ebcb72d84118
Tumor marker for papillary carcinoma of thyroid is ?
Calcitonin
Thyroglobulin
Chromogranin A
Tyrosinase
1b
single
Thyroglobulin is a glycoprotein specific to the follicular cell, facilitates the conversion of MIT and DIT into T3 and T4. Measurement of peripheral thyroglobulin has predictive value for the recurrence of DTC (differentiated thyroid cancers) locally or in metastatic deposits after initial total thyroidectomy Source : ...
Surgery
Endocrinology and breast
4ff7047e-d3d4-44a2-8bdc-a2b687e178e4
Auditory pathway passes through:
Medial geniculate body
Lateral geniculate body
Reciculate formation
Cerebellar fornix
0a
single
Ans. A Medial geniculate body I. Auditory pathway: SC-SLIM-41,42 II. S- Spiral ganglia (cochlea) III. C- Cochlear nuclei (ponto-medullary junction) IV. S-Superior olivary nucleus (pons) V. L-Lateral lemniscus (brain stem) VI. I-Inferior colliculus (mid-brain) VII. M-Medial geniculate body (meta-thalamus) VIII. 41,42 - ...
Anatomy
null
079fd196-d2c4-4c93-8e85-dd52826ff05a
Diaphragmatic hernia can occur through all the following, Except :
Esophageal opening
Costoveebral triangle
Costal & sternal attachment of diaphragm
Inferior vena cava opening
3d
multi
D i.e. Inferior Vena Cava Opening Venacaval openings are not the site of diaphragmatic herniationQ
Anatomy
null
6d4472c7-7c86-4f2e-9723-e83bac0aa092
A person is declared dead if not seen by relatives for how many years -
3 years
7 years
10 years
12 years
1b
single
Ans. is 'b' i.e., 7 yearso A person is legally declared dead if not seen for 7 years from the date of declared missing.
Forensic Medicine
Misc.
8c666534-4470-4f09-bc53-de4b9f86a13b
Used urine bags are disposed in which color bag ?
Red
Yellow
White
Black
0a
single
Ans. is 'a' i.e., Red Contaminated recylable wastes are disposed in which red color bag. These are tubing, bottles, IV tubes, IV sets, catheters, urine bags, syringes (without needles) and vaccutainers (with their needles cut) and gloves.
Social & Preventive Medicine
null
8cc61298-67fb-45a7-b6dd-c71b67eb6d92
All are used in bronchial asthma, except:
Salbutamol
Morphine
Aminophylline
Steroid
1b
multi
Morphine is a drug of emergency, but due care has to be taken in its use.  Infants and the elderly are more susceptible to the respiratory depressant action of morphine.  It is dangerous in patients with respiratory insufficiency (emphysema, pulmonary fibrosis, cor pulmonale); sudden deaths have occurred. Morphine acc...
Medicine
null