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135
823d0894-30c4-41d8-b93d-5734139f18d3
A middle aged man came with fever 2 weeks. He also complains of occasional night sweats and has significant weight loss. BAL was done, in which MTB was not detected. Extra pulmonary TB is suspected. Which of the following sites is most likely affected?
Skeletal system
Gastrointestinal tract
Lymph nodes
Genito urinary tract
2c
single
Lumph nodes are the most common site of extrapulmonary TB. Associated pulmonary disease is present in fewer than 50% of cases. The diagnosis is established by fine needle aspiration biopsy. Cultures are positive in 70- 80%. In descending order of frequency, the extrapulmonary sites most commonly involved in TB are the ...
Microbiology
Bacteriology
bf300f7c-0856-430f-b55e-efecb015cb1b
. A neonate is seen crying with eyes closed and moving all his limbs. What is the Neonatal Behavioral response scale -
Scale 1
Scale 3
Scale 5
Scale 6
3d
multi
Scale 6 Neonatal behavior assessment scale It is a scale developed by T. Berry Brazelton for evaluating the neurological conditions and behavior of newborn by assessing his or her aleness, motor maturity, irritability and interaction with people. Scores SLEEP STATE I)Deep sleep: - Sleep with regular breathing, eyes clo...
Pediatrics
null
cb7ae32c-5d79-4d98-932f-885cb393d2a9
Ohobaric oxygen is used in
Carbon monoxide poisoning
Ventilation failure
Anaerobic infection
Gangrene
0a
single
.HYPERBARIC OXYGEN It is administration of oxygen 1 or 2 atmospheres above the atmospheric pressure in a compression chamber. It increases the aerial oxygen saturation so that oxygen perfusion of tissues will be increased.Indications 1. Carbon monoxide poisoning. 2. Tetanus, gas gangrene infections. 3. Bedsores, frostb...
Surgery
Urology
b137d458-4957-4d0b-92ef-d242a3a820da
All are true about Exenatide except -
Decreases glucagon secretion
It is GLP 1 analogue
Used in type 1 DM
Given subcutaneously
2c
multi
Ans. is 'c' i.e., Used in type I diabetes mellitus Exenatide is a synthetic glucagon-like peptide -1 (GLP-l) analogue. o It acts similar to GLP-1 --> Enhancement of postprandial insulin release, suppression of glucagon release and appetite as well as slowing of gastric emptying. o It is given by subcutaneous route & us...
Pharmacology
null
0b457836-0c29-42e5-841c-94bb6e6740b0
Smallest diameter of pelvis is?
Interspinous diameter
True conjugate
Diagonal conjugate
Inteuberous diameter
0a
multi
Interspinous diameter REF: Clinical Obstetrics 10th edition by S. Gopalan, Sarala & Jain, Vanita Page 4, Manual of Obstetrics, 3e by Shirish N Daftary Page 11-12, Manual Of Obstetrics (2Nd Edition) by Daftary Page 16-18 "Interspinous diameter (transverse diameter of midpelvis = 10 cm or somewhat more) is the smallest d...
Gynaecology & Obstetrics
null
432370b8-e674-4ca1-b21f-b8b15f5c1089
NSAIDS with least anti inflammatory' action -
Indomethacin
Paracetamol
Ketorolac
Ibuprofen
1b
single
Ans. is 'b' i.e., ParacetamolParacetamolo It does not possess anti - inflammatory activity because it is ineffective in the presence of peroxides generated at the site of inflammation.o It produces very little GI toxicity and can be administered in patients intolerant to other NSAIDs.
Pharmacology
Prostaglandins
2dba6ccc-eaba-40b5-9345-08c63fec6e6d
H is helpful in all of the following except
Vaginal atrophy
Flushing
Osteoporosis
Coronary hea disease
3d
multi
.
Gynaecology & Obstetrics
All India exam
709e9acd-83c8-4c25-8041-5e7df4f9c83c
Direct fibrinolytics are/is:
R4prourokinase
Alfimiprase
rtpA
All
1b
multi
Ans. b (Alfimeprase). (Ref. Harrison's medicine 16th ed. 690)Alfimeprase is a metalloproteinase that degrades fibrin in a plasmin-independent fashion. It is a novel thrombolytic based on snake venom derived protein. It is a direct fibrinolytic. It is not a plasminogen activator. It is neutralized by alpha-macroglobulin...
Pharmacology
Hematology
9638270b-74f0-400b-b3e8-dcc8612cf736
A 2 day old newborn baby presented with microcephaly, macroglossia, visceromegaly and a blood glucose level of 20 mg/dl. What is the most likely diagnosis
Prader–Willi syndrome
Beck with–Wiedman syndrome
Werner syndrome
Cockayne syndrome
1b
single
null
Pediatrics
null
32790a09-f519-4c46-9354-5bb020b75db3
Drug of choice for sedation of a patient in ICU is: September 2009, March 2013 (a)
Diazepam
Lorazepam
Propofol
Alprazolam
2c
single
Ans. C: Propofol Benzodiazepines, e.g. diazepam, lorazepam and midazolam, are widely used as sedative agents in the ICU. Diazepam use has become less common as newer shoer-acting benzodiazepines have become available. Lorazepam is more potent than midazolam and, because of its low lipid solubility, crosses the blood-br...
Anaesthesia
null
a86efc20-cdc0-4221-bcf4-1dd46d59f22c
Decreased number of melanocytes are seen in: March 2005
Pebaldism
Albinism
Vitiligo
All of the above
3d
multi
Ans. D: All of the above Melanopenic hypopigmentation is due to decrease in number of melanosomes, which could be due to: Genetic diseases-albinism, piebaldism A utoimmune diseases-vitiligo Post-inflammatory-Discoid lupus erythematosus Piebaldism is due to an absence of melanocytes in affected skin and hair follicles. ...
Skin
null
dbe050ce-c822-48de-93be-a70ed0fb50f6
Dentist act was introduced on
27th March 1948
29th March 1948
27th March 1949
29th March 1949
1b
single
null
Dental
null
f2852a59-4dbd-4568-bccb-26706fe4e82c
A 40 year old patient is suffering from carotid body tumor. Which of the following is the best choice of treatment for him?
Excision of tumor
Radiotherapy
Chemotherapy
Carotid aery ligation both proximal and distal to the tumor
0a
multi
Ans. is 'a' i.e., Excision of tumour
Surgery
null
b42e0068-f0a8-4d38-b7f2-a68b8ce48286
Branchial cyst arises due to-
Failure of obliteration of second branchial cleft
Persistance of urachus
Thymus
Thyroglossal tract
0a
single
Ans. is 'a' i.e., Failure of obliteration of second branchial cleft Brachial Cyst* A branchial cleft cyst is a congenital epithelial cyst that arises on the lateral part of the neck usually due to failure of obliteration of the second branchial cleft in embryonic development. Less commonly, the cysts can develop from t...
Anatomy
Embryology
2c3b3748-4455-49f6-bbfd-c93177fde53f
Most common pulmonary manifestation of SLE:
Shrinking Lung
Pleuritis
Intra alveolar hemorrhage.
Interstitial inflammation
1b
single
Ans. (b) PleuritisRef: Harrisons Principle of Internal Medicine 20th Ed; Page No- 2520Most Common Complication in SLE* Cutaneous Manifestations:# The most common acute SLE rash: Butterfly" rash# Most common chronic dermatitis in lupus: Discoid lupus erythematosus (DLE)* Vascular Occlusions: Myocardial infarctions are p...
Medicine
Respiratory
29735677-15e7-4b29-ae79-ab2ddeda079c
Person having heterozygous sickle cell trait is protected from infection of:
P. falciparum
P. vivax
Pneumococcus
Salmonella
0a
single
Ans. a. P. falciparum (Ref: Robbins 9/e p390, 8/e p387)Person having heterozygous sickle cell trait is protected from infection of P. falciparum."People who are heterozygous for the sickle cell trait (HbS) become infected with P. falciparum, but they are less likely to die from infectionQ. The HbS trait causes the para...
Pathology
Hemolytic anemia
15b7d01c-5d0a-4fd2-a732-d83c965db507
Some micro organisms produce a diffuse spreading inflammatory reaction due to the elaboration of
Coagulase
Peroxidase
Bradykinin
Hyaluronidase
3d
single
null
Pathology
null
afb7e1cc-c579-4b43-93c9-d3ff081e08eb
Johne's bacillus is:
Corynebacterium pseudotuberculosis
M. Paratuberculosis
H. Acgipticus
Micrococcus
1b
single
M. Paratuberculosis
Microbiology
null
1bc4f6ce-6b4d-4798-8dfb-c6b95f196b07
A 30 year ols woman presented with secondary amenorrhoea for 3 years along with galactorrhea. The most likely cause of her symptoms would be -
Craniopharyngioma
Prolactinoma
Meningioma
Sub-arachnoid haemorrhage
1b
single
prolactinoma stimulate pituitary causing excessive milk secretion and it also inhibit GnRH causing decreased FSH &LH level causing secondary amenorrhea (Harrison 17 pg 2206)
Medicine
Endocrinology
ec3f622e-eeda-40af-ba52-c613b3699301
Hypercalcemia is caused by all except:
Thyrotoxicosis
Vit. D intoxication
Sarcoidosis
Furosemide
3d
multi
Answer is D (Furosemide): Thiazide diuretics cause hypercalcemia while loop diuretics (furosemide) cause hypocalcemia. Furosemide is a loop diuretic that is characteristically associated with hypocalcemia and not hypercalcemia.
Medicine
null
14fa16a8-1f89-4de9-9e85-f4ab360f5f2a
All of the following are true regarding chronic active hepatitis, except:
Common in females
Progression to cirrhosis is not seen
Remission with steroids
May associate with autoimmune disease
1b
multi
Chronic hepatitis is defined as a chronic inflammatory reaction of the liver of more than 3-6 months duration, demonstrated by persistently abnormal serum aminotransferase levels and characteristic histologic findings. The causes of chronic hepatitis include. HBV, HCV and HDV autoimmune hepatitis, chronic hepatitis ass...
Medicine
Hepatitis
7baca24a-b67a-471a-9f9e-79ada427357f
HLA is present on -
Sho term of chromosomes 3
Sho arm of chromosomes 6
Long arm of chromosomes 3
Long arm of chromosomes 6
1b
single
Ans. is 'b' i.e., Sho arm of chromosomes 6 o HLA complex of genes is located on the sho arm of chromosome 6.
Pathology
null
0f6e2f1d-6a4f-45d2-85a3-5ecb97c5d8fc
Hemochromatosis affect the following organs
Heart
Pancreas
Skin
All of the above
3d
multi
Ans: dRef: Harrison, 16,hed, p. 2301
Medicine
Blood
e72a3615-f212-4a79-a0f4-87aba20c0cc4
SSRI is first-line treatment for
OCD
Panic disorder
Social phobia
Post traumatic stress disorder
2c
single
In social phobia, among the antidepressants, SSRIs are currently drugs of choice, with paroxetine being the most widely used drug. Other SSRIs, such as fluoxetine and seraline are also equally effective. Fluoxetine has the advantage of a longer half-life. Other antidepressants such as imipramine (TCA) and phenelzine (M...
Psychiatry
Pharmacotherapy in psychiatry
d2017687-25a0-4272-907f-a1e0863c11a9
The most common site of primary osteoarthrosis is -
Hip joint
Knee joint
Ankle joint
Shoulder joint
1b
single
In general, weight bearing lower limb joints are affected more commonly than upper limb joints. However, No textbook has mentioned which is the commonest joint : knee or hip. According to me it is knee because of following facts :- I have seen hardly one or two cases of primary OA of hip; while, I have seen hundreds ...
Orthopaedics
null
19402012-e78f-4a51-bfae-2903aa13e50e
Anemia of chronic renal failure -a) Normocytic normochromic anaemiab) Erythropoietin improves the symptomsc) Dialysis causes severe anemiad) Anemia is proportional to the kidney disease
acd
bcd
abd
ab
2c
single
null
Medicine
null
f6b2ad2a-fe3d-4359-adbe-488acfaee6a0
The classical example of muscular violence is
of fibula
of patella
of clavicle
all of the these
1b
multi
B i.e. of patella
Surgery
null
2159a784-ce33-4e06-9ff2-49f75627c2e1
Which of the following sonographic finding suggests development of preeclampsia
Increased volume of chorionic villi.
Extensive remodelling of spiral arterioles.
Increased invasion of extravillous trophoblastic tissue.
None of the above.
0a
multi
Superabundance of chorionicvilli is implicated in etiopathogenesis of preeclampsia.
Gynaecology & Obstetrics
null
be507d85-3a7a-4b77-86e9-ba220bc70f9f
Copper containing enzyme is
Catalase
Cytochrome oxidase
LDH
None
1b
multi
null
Biochemistry
null
9e74ea99-cd9a-47e7-bd03-95c4f99b8d59
Perl's stain or prussion blue test is for:
Bilirubin
Calcium
Hemosiderin
Glycogen
2c
single
Perls' stain (Prussian-Blue Reaction) is to demonstrate Ferric salts in tissues. These are seen as iron  granules in bone marrow macrophages, erythroblasts (Sideroblasts) and erythrocytes (Siderocytes) in  blood films and haemosiderin in spun urine.
Biochemistry
null
96624c60-6cfb-41f7-94ce-d9ce6c565e73
Secondary hemorrhage is after how many days of tonsillectomy
Within 6 hrs of operation
Within 24 hrs of operation
Within 3 weeks of operation
Within 3 months of operation
2c
single
Secondary haemorrhage (occur from 3rd day onwards (5th to 10th day higher chances) due to sloughing of aeries caused by infection). It is the result of sepsis and premature separation of membrane. Ref : ENT textbook by Dhingra 6th edition Pgno : 430
ENT
All India exam
20255e67-c1c7-4d28-9aab-16c70c500d0b
The most common cuase of renal scarring in a 3 year old child is -
Trauma
Tuberculosis
Vesicoureteral reflux induced pyelonephritis
Interstitial nephritis
2c
single
Ans. is 'c' i.e., Vesicouretrial reflux induced pyelonephritis The small scarred kidney in childhood;. Risdon RA] `Reflux nephropathy is now a generally accepted term to describe small scarred kidneys discovered during childhood; it recognises the close association between this renal lesion and vesicoureteric reflux (V...
Pediatrics
null
dab67c26-3707-4de5-8b91-30e60c3eafeb
In chronic inflammation confined to the portal tract with intact limiting membrane and normal lobular parenchyma, the histopathological diagnosis would be -
Active hepatitis
Chronic active hepatitis
Chronic persistent hepatitis
Acoholic heaptitis
2c
single
Intact limiting membrane with inflammation confined to portal area is seen in chronic persistent hepatitis.
Pathology
null
238d76d9-837c-407e-8399-952a3cf3d851
A neonate born to infected hepatitis-B mother, should be treated with:
Isolation
Immunoglobulins
Hepatitis-B-vaccine
Immunoglobulins and hepatitis-B-vaccine
3d
single
D. Immunoglobulins and hepatitis-B-vaccine(Ref: Nelson's 20/e p 1942-1952)"Infants born to HbsAg positive mothers should receive both Hep B Ig and Hep B vaccine at separate sites within 12 hours of birth, followed by 2nd and 3rd dose of vaccine at 1 and 6 months.
Pediatrics
Gastro Intestinal System
f7aab564-8873-4d84-be7b-bc8381a4cc8c
Advantage of coho study ?
Involves fewer number of subjects
Inexpensive
Suitable for rare disease
More than one outcomes can be studied
3d
single
Ans. is 'd' i.e., More than one outcomes can be studied
Social & Preventive Medicine
null
2271f000-f55d-4774-ab06-c11e5e29450a
The most earliest sign of anterior uveitis is:
Aqueous flare
Keratic precipitates
Constriction of pupil
Raised intraocular pressure
0a
single
Ans. Aqueous flare
Ophthalmology
null
6455f1b0-0aee-4ff5-8448-7b4f1ecdb05a
Ligament of Cooper, used in the surgery for femoral hernia repair, is formed by which of the extentions of inguinal ligament?
Lacunar ligament
Pectineal ligament
Ilioinguinal ligament
Reflected pa of inguinal ligament
0a
single
Answer-A. Lacunar ligamentIt is also called Gimbernat's ligament.From the medial end, deep fibres curve horizontally backward to the medial side of pectin pubis forming lacunar ligament.This ligament is trainagular in shape, with the apex attached to the pubic tubercle.Its sharp lateral edge forms the medial boundary o...
Surgery
null
77445f6f-a991-4bea-8128-852ae5b6105e
False statement about impetigo –
Mostly caused by staphylococcus or streptococcus or both
It predisposes to glomerulonephritis
Produces scar on healing
Erythromycin is drug of choice
2c
multi
Impetigo is a highly contagious (infectious) Gram-positive bacterial infection of the superficial layer of the epidermis. It occurs in two forms :- Impetigo contagiosa (Non-bullous) → Caused by both staph aureus & streptococcus (group `A ) Bullous impetigo Caused by Staph.aureus. Lesions of Impetigo contagiosa heal...
Dental
null
2f2b9b1e-61f7-45cb-a653-76e70b1b4583
Mantoux test reading of less than 5mm indicates
Tuberculosis infection
Disseminated TB
Susceptiblity to TB
Immunity to TB
1b
single
Ref Robbins 9/e p371 Mantoux test is simply able to predict the presence or absent of cell mediated immunity against the tubercular antigens .it cannot differentiate between infection and disease Negative mantoux test just indicates that the individual has not been exposed to tuberculin bacilli
Anatomy
General anatomy
701efbf3-bf83-4797-87c8-3200c6632e1c
Which Vitamin is involved in Redox reactions -
Pyridoxin
Biotin
Folic acid
Riboflavin
3d
single
Ans. is 'd' i.e., Riboflavin VitaminCoenzymeFunction as coenzymeEntity transferredThiamine (Vit B1)Thiamine pyrophosphate (TPP)Oxidative decarboxylation and transketolase reactionHydroxy-ethylRiboflavin (Vit B2)Flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN)Oxidation and reduction reactionHydrogen ato...
Biochemistry
Vitamins
d9f99fbc-bebb-4db3-abff-ba9db4b085a6
A Wahin's tumour is
An adenolymphoma of parotid gland
A pleomorphic adenoma of parotid
A carcinoma of the parotid
A carcinoma of submandibular salivary gland
0a
single
Wahin's tumor Is the second most common benign tumor of the parotid gland (1st is pleomorphic adenoma). It consists of both epithelial and lymphoid elements thus known as adenolymphoma (probably arises from remnants of parotid tissue trapped in lymphnodes within the parotid gland). Also known as papillary cystadenoma l...
Surgery
Head and neck
977df036-1eb8-4de2-badd-0a23b59e225b
Natural killer cells
Belongs to B-cell lineage
Belongs to T-cell lineage
Display cytotoxic effect on tumor cell
Requires previous antigen exposure for activation
2c
single
Natural Killer CellsThe function of NK cells is to destroy irreversibly stressed and abnormal cells, such as virus-infected cells and tumor cells. NK cells make up approximately 5% to 10% of peripheral blood lymphocytes. They do not express TCRs or Ig.NK cells are endowed with the ability to kill a variety of virus-inf...
Microbiology
Immunology
eba12407-7ccc-4146-a72a-b37fd80cca3d
Radioisotope used systemically in Polycythemia rubra vera.
32p
131I
Strontium-89
Rhenium-186
0a
multi
32p - Polycythemia rubra vera. Rhenium -186; Painful bone metastasis.
Radiology
null
557d6593-08fc-4abf-aa48-5a4ddbd9e594
Life span of CuT 380 A is -
10 years
8 years
4 years
5 years
0a
single
Ans. is 'a' i.e., 10 years o The longest life span is of CuT380A: 10 years.IUDsLife spanFirst generation:Lippe's loop (obsolete)--Second generationCopper-T--CuT-200-B4 yrCuT-2003yrCuT-220C--Nova-T5 yrMultiload - 2503 yr3755 yrCuT-3 80A10 yrThird generationProgestasert1 yrLNG-20 (Mirena)5 yr (Ref: Novak p263; Note that ...
Gynaecology & Obstetrics
Non-Hormonal - Intrauterine Devices
d5bb73ad-1472-4bc4-9a31-8e0abab3e418
Herpes simplex infection can lead to?
Frontal lobe infarction
Parietal lobe infarction
Temporal lobe involvement
Occipital neuralgia
2c
single
Ans. is 'c' i.e., Temporal lobe involvement Pathology of Herpex simplex encephalitis:o Herpes simplex infection has a prediliction for the involvement of Temporal lobe.o The lesions in HSV encephalitis are intense hemorrhagic necrosis of the inferior and medial temporal lobe and the mediorbital part of frontal lobes.o ...
Medicine
Infection
31608513-c271-49e8-b833-7a55d2d1ab75
Corbohydrate reserve of human body
350 gm
600 gm
950 gm
1500 gm
0a
single
Ans. is 'a' i.e., 350 gmCarbohydrate store of body is approximately 350 grams (70 grams hepatic glycogen and 280 grams muscle glycogen).
Social & Preventive Medicine
null
802b5bec-215a-462d-b053-62c0e5af3894
Which cranial nerve is commonly involved in meningeal tuberculosis infection?
7th nerve
8th nerve
Ocular nerve
Oculomotor nerve
2c
single
Meningeal involvement is pronounced at the base of the brain, paresis of cranial nerves (ocular nerves in paicular) is a frequent finding. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 1348
Medicine
null
16640d79-bcfe-4f1f-be63-419d6a3c6874
A 20 year old man presented with hemorrhagic colitis. The stool sample grew Escherichia coli in pure culture. The following serotype of E. coli is likely to be the causative agent -
0 157 : H7
0 159 : H7
0 107 : H7
0 55
0a
single
Ans. is 'a' i.e., 0157 : 117
Microbiology
null
ce68127c-5b6f-4efb-92d2-55c694331993
17 D vaccine is used for the prevention and control of-
Yellow fever
Japanese encephalitis
Haemorrhagic fever
Dengue
0a
single
null
Social & Preventive Medicine
null
2d58a218-9118-45e1-b2d6-7b01e36dcffc
MRI is unsuitable for:
Cardiac pacemakers
Metallic clips
Woody items
All of the above
3d
multi
(All of the above) (19-Sutton 7th)MAGNETIC RESONANCE IMAGINGADVANTAGESDISADVANTAGES* It is non-invasive technique* It is safe as it does not involve the use of ionising radiation* There is no adverse biological effect.* Images can be readily produced in any plane eg. Axial sagittal or coronal without changing position ...
Medicine
Miscellaneous
3de7ebb7-c191-4ea9-bbac-4a23d3b6025c
Cytochrome P450 is identified to 11-ss hydroxylase is known as
CYMA-IB
CYPA-2B
CYPA-3B
CYPA-4B
1b
single
Cytochromes P450 (CYPs) are a family of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are impoant for the clearance of various compounds, as well as for hormone synthesis and breakdown Ref: guyton and hall textbook o...
Physiology
Endocrinology
d4d3c56d-5b55-49bf-845b-4128ff053407
True regarding level of sugar in hyperosmolar non ketotic hyperglycemia is: September 2005
No change
Mild elevation
Moderate elevation
Severely elevated
3d
multi
Ans. D: Severely elevated Hyperglycemic hyperosmolar nonketotic syndrome (HHNS) is being diagnosed with increasing frequency in obese children with type 2 diabetes mellitus (T2 DM). The syndrome is characterized by severe hyperglycemia, a marked increase in serum osmolality and dehydration without accumulation of beta-...
Medicine
null
7183c715-5517-42cb-84bd-47d08d1d36ab
Premalignant bone lesion among the following is -
Pagets disease
Osteoid osteoma
Osteochondroma
Enchondroma
0a
single
Ans. is 'a' i.e., Pagets disease Paget's disease o Paget s disease is characterized by increased bone turnover and enlargement and thickening of the bone the internal architecture is abnormal and the bone is usually brittle, o Primary defect is in osteolastic. o It is marked by regions of furious osteolastic bone resor...
Unknown
null
afc9a7aa-ea95-4bda-adef-6c0c157909bd
Which among the following is the epithelial lining of vagina?
Stratified squamous non-keratinized
Columnar
Stratified squamous keratinized
Cuboidal
0a
single
There are two types of stratified squamous epithelia: nonkeratinized and keratinized. Nonkeratinized epithelium exhibits live surface cells and covers moist cavities such as the mouth, pharynx, esophagus, vagina, and anal canal. Keratinized epithelium lines the external surfaces of the body.
Anatomy
null
5d79dffd-dde1-4967-bc9d-0910b7926218
Drug of choice for hypeension crises in systemic sclerosis is
Beta blocker
Losaan
ACE inhibitor
Nitrates
2c
single
One of the main causes of death is hypeensive renal crisis, characterised by rapidly developing malignant hypeension and renal failure. Hypeensive renal crisis is much more likely to occur in DCSS than in LCSS, and in patients with topoisomerase 1 antibodies. Hypeension should be treated aggressively with ACE inhibitor...
Medicine
Immune system
124d7216-461a-4c4d-a0cd-1f13b6bce740
The conversion of an optically pure isomer into a mixture of equal amounts of both dextro and levo forms is called as-
a) Polymerization
b) Stereoisomerism
c) Racemization
d) Fractionation
2c
multi
Racemic Mixture - Equimolar mixture of optical isomers which has no net reaction of plane polarized light.
Biochemistry
null
5afecdc0-0cdb-4b86-bba4-c0bb343e6a39
Apoptosis is?
Internally controlled, programmed cell death
Externally controlled, programmed cell death
Internally controlled, programmed enzyme degradation
Externally controlled, programmed karyolysis
0a
multi
Ans. (a) Internally controlled, programmed cell deathRef: Robbin's pathology 9th ed. /52* Apoptosis is internally controlled, programmed cell deathSalient Features of Apoptosis:* No inflammation* Cell shrinkage* Formation of apoptotic bodiesExample* PhysiologicahEmbryogenesis, Organogenesis, Men- struation* Pathologica...
Pathology
Apoptosis
3b909ad5-c40f-4013-85df-1a402a8b9fc4
Posterior ethmoidal sinus drains into (JIPMER May 2019)
Spheno-ethmoidal recess
Superior meatus
Middle meatus
Inferior meatus
1b
single
- There are 3 groups of ethmoidal air sinuses Anterior Middle Posterior - Posterior ethmoidal sinus is opening in lateral wall of the nose. - Lateral wall of the nose has 3 elevations called superior, middle & inferior turbinates / conchae - Under each turbinate, there is space called meatus called superior, middle & i...
Anatomy
JIPMER 2019
7664873d-ed28-4cad-8799-4ac424bc7f63
Following are the clinical features of Leber optic neuropathy except
Seen in the 2nd or 3rd decade of life
It is a example of gradual painless visual loss
Males can transmit the disease
No leak of dye is observed in fluorescein angiography
2c
multi
Ans. is 'c' i.e., Males can transmit the disease Leber's Hereditary optic neuropathv Leber's hereditary optic neuropathy is characterized by sequential subacute optic neuropathy in males aged 11-30 years. The underlying genetic abnormality is a point mutation in mitochondria! DNA. Since mitochondrial DNA is exclusively...
Ophthalmology
null
a83bb49c-f940-4968-910c-33b703faef2f
Radiation of 5 Gy will kill patients in: March 2013 (b, c, d, e, f)
1 day
1 week
2-3 weeks
4-6 weeks
3d
single
Ans. D i.e. 4-6 weeks
Radiology
null
9dc53c99-27ab-4e67-a660-bd33707fbb55
Regarding anaplastic carcinoma which statement is false
Common in elderly
Associated with P53 mutation
Surrounding neck tissue is usually infiltrated
Radiotherapy cures
3d
multi
More commonly seen in elderly women. Local infiltration is an early feature of these tumours with spread by lymphatics and by the bloodstream. They are extremely lethal tumours and survival is calculated in months. p53 mutations are found in 15% of tumors, Source : Sabiston 20th edition Pg: 910
Surgery
Endocrinology and breast
6a2008ad-90b7-46ec-8b01-422d1cd3ad8e
A 56-year-old man is diagnosed with an extradural tumor in the posterior cranial fossa. When the patient protruded his tongue during physical examination, the tongue deviated to the right. Which of the following muscles and nerves are most likely injured?
Right hypoglossal nerve and right genioglossus
Left hypoglossal nerve and left genioglossus
Right hyoglossus and left styloglossus
Right geniohyoid and first cervical nerve
0a
single
The hypoglossal nerve innervates the muscles of the tongue and is therefore directly involved in alteration of shape and movement of the tongue. A lesion in this nerve would cause deviation of the tongue toward the injured side, which could be observed upon protrusion of the tongue. The genioglossus is the major muscle...
Anatomy
Head & Neck
5f9056e8-2364-4f13-926e-7853c4a561f0
Staphylococcus differs from streptococcus by:
Coagulase test
Catalase test
Phosphatase
Gram negative
1b
single
Ans. is 'b' i.e., Catalase test(Ref: Ananthanarayan, 9th/e, p. 200 and 8th/e, p. 196)* Coagulase test is used to differentiate the different species of staphylococci (staph, aureus, staph, epidermidis).* Catalase test is used to differentiate staphylococci from streptococci.* Coagulase test cannot be used to differenti...
Microbiology
Bacteria
df20a02a-2444-4503-9a36-722ccedbe7eb
A 6-month old infant presented with multiple papules and exudative lesions on the face, scalp, trunk and few vesicles on the palms and soles for 2 weeks. His mother had a history of itchy lesions.The most likely diagnosis is :
Scabies
Infantile eczema
Infantile seborrhoeic dermatitis
Impetigo contagiosa
0a
single
Ans. is 'a' i.e., Scabies Vesicobullous lesion in an infant can be seen in Scabies Infantile eczema Seborrheic dermatitis The clincher here is involvement of palms and soles. This is a characteristic feature of scabies in infants * Differential diagnosis Scabies Infantile eczema Characteristic distribution: Lesions pre...
Unknown
null
6cc4ed27-ae50-44fb-8167-387e285534ac
In tandem bullet, number of bullet/ bullets coming out of the gun is/are:
1
2
3
4
1b
single
2
Forensic Medicine
null
316c3d2f-0f5b-4786-9c4e-fff6eef37d71
All of the following conditions may be associated with Pancytopenia and Splenomegaly, Except
Aplastic Anemia
Hairy Cell Leukemia
Myelofibrosis
Hypersplenism
0a
multi
Answer is A (Aplastic Anemia) Splenomegaly is typically absent in patients with aplastic anemia, and if present, the diagnosis of aplastic anemia should be questioned and search for another associated pathology be initiated Splenomegaly, Lymphadenopathy and Hepatomegaly in Aplastic Anemia The finding of splenomegaly or...
Medicine
null
c6f36cb1-2587-4647-863b-98835b737355
If both parents are sickle cell anemia patients then the likelyhood of offsprings having the disease is-
10%
25%
50%
100%
3d
multi
Sickle cell anemia is autosomal recessive.
Pathology
null
8d8e32be-d0b8-4cce-b382-d65d00d3ebad
Scotochromogens are: (PGI Dec 2008)
Mycobacterium Gordonae
Mycobacterium Marinum
Mycobacterium Intracellulare
Mycobacterium avium
0a
single
Ans: A (Mycobacterium Gordonae) M. Marinum & M. Kansasii are photochromogenes while M. intracellulare & M. avium are non-photochromogenes.Scotochromogens# M, Gordonae (formely M.aquae) - Often found in tap water (hence called 'the tap water scotochromogen), is a common contaminant in clinical specimens and a rare cause...
Microbiology
Bacteria
a9455f00-fdac-4ad0-8663-b432c3f84799
The most common site of rupture of Abdominal Aortic-Aneurysm is
Laterally into the Left Retroperitoneum
Laterally into the Right Retroperitoneum
Posteriorly into the Posterior Retroperitoneum
Anteriorly into the Peritoneum (Intraperitonial)
0a
multi
null
Surgery
null
14d9cae9-2b65-4a16-9d24-7e4d66c126f1
A 3 month baby can do:
Social smile
Can sit without suppo
Transfer objects from right to left
Can change position from prone to supine
0a
single
Social smile appears at 3 months
Pediatrics
Social and Language Milestones
eee95682-65f1-4f9b-887b-96bcad4b41ac
Child of 6 weeks with Hemoglobin of 10 gm% pale on examination, diagnosis is -
Physiological anemia
Pathological anemia
Thalassemia
Iron dificiency anemia
0a
single
Ans. is 'a' i.e., Physiological anemia o Physiologic Anemia of InfancyHemoglobin drops to low point at age 6 to 8 weeksErythropoietin nadir drops HemoglobinTerm Infants: Hemoglobin drops to 9-11 g/dlPreterm Infants: Hemoglobin drops to 7-9 g/dlo No work-up or treatment unless Hemoglobin lower than expected Other point ...
Pediatrics
Anemias of Inadequate Production
f61646b1-e81a-4592-990d-968991f1b156
A 15 year old girl was admitted to the infectious disease hospital with a provisional diagnosis of rabies. The most suitable clinical sample that can confirm the antemortem diagnosis is-
Serum for anti-rabies IgG antibody
Corneal impression smear for immunofluorescence stain
CSF sample for viral culture
Giemsa stain on smear prepared from salivary secretions
1b
single
For the antemortem diagnosis of rabies, viral antigens can be demonstrated in the corneal smear, skin biopsy from the face or neck or saliva.
Microbiology
null
481df4bc-6b5f-4728-a35a-f3eb735d762c
All of the following are microsomal enzyme inhibitors except
Glucocoicoids
Cimetidine
Ciprofloxacin
INH
0a
multi
Other inhibitors- Ketoconazole, Metronidazole, Allopurinol, Erythromycin, OCPs, Omeprazole
Physiology
All India exam
a9fe12f7-57f8-4f2d-90d0-55426043e20d
Amount of radiation used in mammography -
0.5 mSv
0.7 mSv
0.9 mSv
1 mSv
1b
single
Ans. is'b'i.e.,0.7 mSvScreening mammography and radiation A screening mammogram is an X-ray of the breast tissue for women without any breast symptoms.It uses low doses of radiation (about 0.7mSv for 4 X-rays).
Radiology
null
c02c97aa-cb2d-403d-909c-efcc2d5851f8
The structure that lies lateral to distal radial tubercle
Extensor pollicis longus
Extensor carpi radialis longus
Brachioradialis
Extensor carpi ulnaris
1b
single
The structure that lies lateral to distal radial tubercle are: Tendons of Extensor carpi radialis brevis and longus. Distal radial tubercle (Lister's tubercle) is located at the distal dorsal aspect of the radius It is a bony prominence that can be easily palpated. Function: It acts as a pulley for the Extensor Pollici...
Anatomy
Muscles of arm and forearm region & Cubital fossa
d2dc91ad-da8a-4713-9f51-8499aef5a8f3
Best imaging study for the earliest diagnosis of cerebral infarct-
FLAIR MRI
Non-contrast CT
CECT
Diffusion-weighted MRI
3d
single
Diffusion-weighted MRIDiffusion-weighted MRI detects cytotoxic edema in just a few hours of infarction.
Radiology
null
8858d292-5cd2-40f5-9d16-317e77a3d011
Effect of infusion of hypotonic saline?
Increased ICF only
Increased ECF only
Increased in both ICF and ECF
Increased ICF and decreased ECF
2c
multi
Ans. is 'c' i.e., Increased in both ICF and ECFAfter infusion of hyptonic saline causes a decline in plasma osmolality and a shift of water into interstial space (as water moves from higher osmolarity to lower osmolarity), causing decrease in ICF osmolality.This results in shift of water from ECF to ICF.Finally, both E...
Physiology
null
ec87dcd0-e222-4d82-a7e1-d1cbcf831710
Which of the following is not true about fibroblasts?
Secrete & Synthesize collagen
Derived from blood precursor cells
Migrate to wound along fibres used as scaffold
Large fibrin clot acts as barrier to fibroblast penetration
1b
multi
null
Pathology
null
40a7ba32-30bd-4e4e-8521-f690bff12ed6
All of the following structures are developed from Septum transversum, EXCEPT:
Coronary ligament
Falciform ligament
Lesser omentum
Ligamentum teres hepatica
3d
multi
Structures developed from septum transversum:1. Diaphragm (central tendon)2. The fibrous pericardium3. The falciform ligament4. The stroma and capsule of the liver5. The triangular and coronary ligaments6. The lesser omentum The round ligament of the liver (ligamentum teres hepatica) is an embryological remnant of the ...
Anatomy
null
6de209bb-4110-403b-9938-375289db82ec
A 40 year old male patient complains of diminished vision during night and dryness of eyes. Patient gives history of recurrent bacterial infections. Ophthalmic examination reveals white triangular plaques on conjunctiva. This patient is suffering from deficiency of:
Vitamin D
Vitamin B
Vitamin A
Vitamin C
2c
single
Night blindness (nyctalopia) is one of the earliest symptoms of vitamin A  deficiency. Severe deficiency of vitamin A leads to xerophthalmia. This is characterized by dryness in conjunctiva and cornea, and keratinization of epithelial cells. In certain areas of conjunctiva, white triangular plaques known as Bitot's spo...
Biochemistry
null
83209a74-c40b-4769-894d-70ab48cd4e00
The usual incubation period of pertusis is -
7-14 days
3-5 days
21-25 days
Less than 3 days
0a
single
null
Social & Preventive Medicine
null
053485fa-4a38-44a1-b70a-687af2906c74
Which helps in the production of more glucose?
Pyruvate kinase
Pyruvate carboxylase
PDH
Pyruvate decarboxylase
1b
single
Reversal of the reaction catalyzed by pyruvate kinase in glycolysis involves two endothermic reactions. Mitochondrial pyruvate carboxylase catalyzes the carboxylation of pyruvate to oxaloacetate, Key Gluconeogenic Enzymes 1. Pyruvate carboxylase.Pyruvate Carboxylase Reaction Pyruvate in the cytoplasm enters the mitocho...
Biochemistry
Metabolism of carbohydrate
ccd55f48-b485-4c42-ac56-1268633b02e1
8000 rads dosage in Cancer cervix is given to -
Point A
Point B
Side walls of pelvis
None of the above
0a
multi
Ans- A a. External beam via cobalt or linear accelerator & brachytherapy (e.g. Radium, cobalt or cesium) are used in the treatment of carcinoma cervix. b. The radium dosage is calculated with respect to the amount of irradiation received at 2 theoretical points a & b. c. Point a lies 2cm above & 2cm lateral to the base...
Unknown
null
57896e7c-3419-4fdf-82a9-7bac2c5fb92a
HPV vaccine is ?
Monovalent
Bivalent
Quadrivalent
Both bivalent and Quadrivalent
3d
multi
Both bivalent and Quadrivalent Currently, there are two types of cervical cancer vaccines available Gardasil vaccine (quadrivalent vaccine) Cervavarix vaccine (Bivalent vaccine) Gardasil vaccine Gardasil is a quadrivalent human papillomavirus vaccine. Gardasil is the only vaccine that helps protect against 4 types - ty...
Pediatrics
null
321bd3cc-44bf-45db-9195-e95fe30a9664
Rhabdomyolysis with myoglobinuria seen in -
Viper bite
Heat stroke
Malignant hyperthermia
Multiple hornet stings
3d
single
null
Medicine
null
cae21cc5-b191-4ee9-8fbe-d3f083837659
The prognosis is best in rapidly progressive (crescentic) glomerulonephritis associated with:
Poststreptococcal glomerulonephritis
Systemic lupus erythematosus (SLE)
Henoch-Schoenlein purpura
Polyaeritis nodosa
0a
single
Rapidly progressive glomerulonephritis may occur in association with the five diseases mentioned and also with periaeritis (polyaeritis) nodosa, Wegener's granulomatosis, and essential cryoglobulinemia. Some cases arise without a known antecedent disease (idiopathic). Although the prognosis is poor in all types of rapi...
Pathology
null
d611f107-561b-46c6-b8a3-ea26dbf94c89
Which of the following causes a dead end infection?
C. tetani
V. cholerae
S. aureus
Hemophilus
0a
single
Ans. A. C. tetani.Since, there is no further human to human transmission, tetanus is a dead end infection.Dead end infections in humans-Tetanus, Legionnaire's disease, Leptospirosis, Lyme's diseaseRabies, JE, West Nile fever, Equine encephalitis, KFDCysticercosis, Hydatid disease, Trichinellosis, Babesiosis
Microbiology
Bacteria
1e279b6c-588d-4bc9-95b6-1f8d309e0389
Phossy jaw is caused by-
White phosphorus
Red Phosphorus
Arsenic
Antimony
0a
single
Ans. is 'a' i.e., White Phosphorus o Phossy jaw is caused by phosphorus poisoning. All phosphorus poisoning are caused by white (yellow) phosphorus (Red phosphorus is nontoxic).Phosphorus poisoningo Phosphorus is a protoplasmic poison affecting cellular oxidation and causing anoxic necorbiosis, classically affecting li...
Forensic Medicine
Forensic Toxicology - Concepts, Statutes, Evidence, and Techniques
1dc227ae-ac70-4359-8d4b-5916ab9b5eb1
The kidney stone whose development is seen most commonly is:-
Calcium oxalate
Triple phosphate
Uric acid
Cysteine
0a
single
Commonest stone seen in in kidney - Calcium oxalate Other types of kidney stones : Triple phosphate - Ca, NH4+ ,MgP04 Uric acid Cysteine stones
Pathology
Kidney disorders
c969a7ef-dec0-4f9a-afd9-77b69cdeeb8c
A 25-year-old man requests cholesterol screening because of a family history of premature coronary artery disease (CAD). His lipid levels reveal an elevated total and LDL cholesterol. The high-density lipoprotein (HDL) and triglyceride values are normal. His physical examination is completely normal. Which of the follo...
familial combined hyperlipidemia
familial hypercholesterolemia
familial defective Apo B
Apo C-II deficiency
0a
single
Familial combined hyperlipidemia has an incidence of 1/100. It is an autosomal dominant disorder and different affected family members may display different dyslipidemic phenotypes. Familial hypercholesterolemia (1/500) and familial defective Apo B (1/1000) are also common. The other two disorders (Apo C-II deficiency ...
Medicine
Endocrinology
c496e51a-8fd4-481b-828c-c725b6f434a6
True about Trotters triad -a) Conductive deafnessb) Involvement of CN VIc) Involvement of CN Xd) Palatal paralysise) Associated with nasopharyngeal angiofibroma
acd
ad
bc
bde
0a
multi
null
ENT
null
4cf1630b-ae87-4dca-9a61-3f6193902aee
List of the charges established or agreed to, by a dentist for specific dental services:
Table of allowances
Fee schedule
Reasonable fee
Capitation
1b
multi
null
Dental
null
7254b3c4-efb8-47d6-b910-f49b241183b1
All of the following can be administered in acute highpeension during labour except
IV labetalol
IV nitroprusside
IV hydralazine
IV esmolol
1b
multi
Ref - KDT7/e p572 Sodium nitroprusside is contra indicated in eslampsia
Pharmacology
Cardiovascular system
a843da51-7ae7-464f-9c2b-3bb7efe762b0
Labetalol is an
Alpha 1 blocker
Alpha 2 blocker
Alpha 1 and selective beta 1 blocker
Alpha 1 and non-selective beta blocker
3d
single
Labetalol is a commonly used a 1 and non-selective b-adrenergic blockerDose: 200-2400mg/day, orally in two to three divided dosesIn an emergency: 20mg IV, followed by 20-80mg every 20min to a maximum of 220mg. Avoid in patients with Asthma, congestive cardiac failure, Liver failure(Ref: William's Obstetrics; 25th editi...
Gynaecology & Obstetrics
All India exam
49764201-1e0b-4c29-9729-d5ef2b1a886f
True about Ringer's Lactate -
Isotonic
Colloidal solution
Potassium level is same as that of serum potassium
Helps in acidosis by acid neutralization
0a
multi
Ringer's lactate solution (RL), also known as sodium lactate solution and Hamann's solution, is a mixture of sodium chloride, sodium lactate, potassium chloride, and calcium chloride in water. It is an isotonic solution .it is used for replacing fluids and electrolytes in those who have low blood volume or low blood pr...
Medicine
Fluid and electrolytes
c866dee1-d931-48a6-8749-d3884e68fb72
Submandibular gland is divided into superficial and deep parts by -
Digastric
Geniohyoid
Mylohyoid
Stylohyoid
2c
single
Ans. is 'c' i.e., Mylohyoid Submandibular glando This walnut sized gland lies belowr the mandible in the anterior part of digastric triangle. It is J-shaped and consists of a large superficial and a small deep parts, separated by mylohyoid muscle and continuous with each other around the posterior border of mylohyoid m...
Anatomy
Salivary Glands
6aa5d556-3305-41bf-b989-db4563d4a91f
Treatment of choice for genital was in pregnancy is:
Salicylic acid with lactic acid solution
Imiquimod
Podophyllotoxin
Cryotherapy
3d
single
During pregnancy, electrocoagulation, cryotherapy, or CO2 laser therapy should be administered at approximately 32 weeks to avoid, on one hand, post-treatment necrosis, which may last as long as 4-6 weeks, and to prevent, on the other hand, recurrence if treated too early. Podophyllin, podofilox, and imiquimod should n...
Gynaecology & Obstetrics
null
40fc36c5-ec55-40db-8042-635a01c0975c
Apgar stands for: (Asked twice in exam)
Attitude pulse grimace activity respiratory effort
Attitude pulse grimace appearance respiratory effort
Appearance pulse grimace activity respiratory effort
Appearance pulse grimace attitude respiratory effort
2c
single
ANS. C
Pediatrics
New Born Infants
5b02dca8-07c2-4806-a2e2-06c3c16f7a3f
The false statement associated with Kaposi's sarcoma is:
Caused by human herpes virus 8
Seen in immune suppressed persons
Proliferative tumor of the blood vessels
Surgery is the treatment of choice
3d
multi
Kaposi sarcoma, a vascular tumor ,induced by HHV 8. The lesions of KS are characterized by the proliferation of spindle-shaped cells that express markers of both endothelial cells and smooth muscle cells. There is also a profusion of slit like vascular spaces, suggesting that the lesions may arise from primitive mesenc...
Pathology
Immunodeficiency Disorders
dcaa2d7b-0c25-4e12-b372-a40f48f351ec
Which of the following is the preferred antiarrhythmic agent in a patient with cardiac arrest:
Amiadorone
Lidocaine
Procainamide
Atropine
0a
single
Answer is A (Amiodarone) Amiodarone is the preferred antiarrhythmic agent jiff resuscitation in a patient with cardiac arrest. Amiodarone is the preferred antiarrhythmic agent for resuscitation, In patients with VF/VT that does not respond to CPR, defibrillation, and vasopressor therapy. Amiodarone is the first-line an...
Medicine
null