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135
0dff9055-671f-458e-8eaa-4d92d0ba6577
True about blood transfusion reaction -a) Complement mediated severe haemolysisb) Renal blood flow is decreasedc) Transfusion should not be stoppedd) Death is not seen
ac
ab
ad
bc
1b
multi
null
Medicine
null
c0a15c33-0d57-467f-9c65-766a5fdc9317
Raygat's test is based on:
Weight of lung
Specific gravity of lung
Consistency of lung
Volume of lungs
1b
single
Hydrostatic test/ Raygat's test: Principle: Specific gravity of lung before respiration is 1.04-1.05 and it becomes 0.94-0.95 after respiration. This makes the respired lung to float. Procedure: Dissect out the fetal lungs & Put into a trough of water and observe. Liver is used as control Inference: If they sink--unres...
Forensic Medicine
Infant deaths & child abuse
2c02e114-541a-4ec5-a4b5-3d14e042736b
What is a percentage of endothelial cell loss during Descemet's stripping automated endothelial keratoplasty –
0 – 5%
10 – 20%
30 – 40%
50 – 60%
2c
single
Endothelial cell loss is a known phenomenon of endothelial keratoplasty (including DSAEK). I am not sure about the answer as various studies have given different values at a different time (post-operatively). First read following statements which are supporting my answer:- "Current modifications of EK such as DSAEK ha...
Ophthalmology
null
35ec19f6-5e5d-4a7e-8c23-545321d97d56
About scurvy, all are true EXCEPT: September 2012
Subperiosteal hematomas with tenderness
Separation of epiphysis
Raised serum alkaline phosphatase
Gingival bleeding
2c
multi
Ans. C i.e. Raised serum alkaline phosphataseScurvyBleeding into skin & joints,Wimberger sign,Pseudoparalysis etc.
Pediatrics
null
062fef8a-aafa-46ed-9dc5-4a4ab8392943
Nitric oxide is synthesized from which amino acid:
Arginine
Serine
Threonine
Lysine
0a
single
NO is also called as Endothelium Derived Relaxing Factor (EDRF). NO (nitric oxide) is synthesized from arginine by enzyme NOS (Nitric oxide synthase) in the endothelial cells. It requires 5 cofactors:- NADPH FAD FMN Heme and Tetrahydrobiopterin (BH4). The vasodilator - nitroglycerin also enters smooth muscle cells, whe...
Biochemistry
Classification and metabolism of amino acids
43af16ba-8587-45f1-a166-bc772e57066d
For spinal anesthesia, lignocaine is used as
0.5 % solution
1 % solution
2 % solution
5% solution
3d
single
Lignocaine is used as 5% (heavy) for spinal anaesthesia.
Microbiology
All India exam
13b2ef45-5d34-434f-b222-e917e1921288
Post dislocation of hip leads to which attitude of the lower leg:
Adduction, external rotation and flexion
Adduction, internal rotation and flexion
Abduction, external rotation and flexion
Abduction, internal rotation and flexion
1b
single
B i.e. Adduction , internal rotation and flexion
Surgery
null
f61ec5c8-8e69-408a-ac50-00d4e5b666a0
Regarding rheumatoid ahritis, all of the following statements are true except-
The cricoarytenoid joint may be involved
HLA-D4 and HLA-DR4 are positive in patients with seropositive rheumatoid ahritis
Subcutaneous nodules are more frequent in seronegative patients
Diffuse intestinal fibrosis and pneumonitis may occur
2c
multi
Rheumatoid nodules occur almost exclusively in RF or ACPA positive patients, usually in extensor tendons . Theyare frequently asymptomatic but some may be complicated by ulceration and secondary infection . Ref Davidsons 23e p1023,1024
Medicine
Immune system
2c41fd2e-8f64-46b3-9bb8-a33ee60b4a85
Difference between rantidine & cimetidine is -
Ranitidine is 5 times more potent than cimetidine
Cimetidine is 5 times more potent than ranitidine.
Ranitidine has androgenic action
Ranitidine more markedly inhibits hepatic metabolism
0a
single
Ans. is 'a' i.e., Ranitidine is 5 times more potent than cimetidine o Ranitidine has several desirable features compared to cimetidine:5 times more potent than cimetidine.No antiandrogenic action, does not increase prolactin secretion or spare estradiol from hepatic metabolism - no effect on male sexual function or gyn...
Pharmacology
G.I.T
e560e0c6-fc39-47d8-b789-c953a61efb3e
In a slow sand filter, the element responsible for yielding bacteria-free water is the -
Valve
Vital layer
Supernatant water
Under-drainage system
1b
single
Ans. is 'b' i.e., Vital layer
Social & Preventive Medicine
null
85331ecd-bbaa-4892-8c55-74cd64e10b90
Name the intrauterine contraceptive device:
CuT 200
Multiload 375
CuT 380A
LNG-IUS
1b
single
Above image is of Multiload-375 -- Device is available in a sterilized sealed packet with an applicator. There is no introducer and no plunger. It has 375 mm2 surface area of copper wire wound around its veical stem. Replacement is every 5 years.
Gynaecology & Obstetrics
Contraceptives
37fe1e93-be97-41aa-837e-392ad0809b2d
A father forced his relictant son to bring a glass of water and the child dropped the glass on the way. This is an example of
Reaction formation
Denial
Passive aggression
Acting out
2c
single
Passive aggression is an immature defense mechanism where a person indirectly expresses anger towards others.
Psychiatry
null
d77edfcc-8984-42cc-97f2-682507eeb943
NOT a feature of Horner's syndrome
Exophthalmos
Ptosis of upper eyelid
Miosis
Anhydrosis
0a
single
(A) Exophthalmos # HORNER'S SYNDROME:> Enophthalmos, Ptosis, Miosis, & Ipsilateral loss of sweating (Anhydrosis)> Malignant pleural effusion often leads to dyspnea.> Pancoast's (or superior sulcus tumor) syndrome results from local extension of a tumor growing in the apex of the lung with involvement of the eighth cerv...
Medicine
Miscellaneous
e9e7b47c-c666-4daa-9f0d-7075b21ed848
The most impoant sign of significance of renal aery stenosis on an angiogram is:
A percentage diameter stenosis >70%
Presence of collaterals
A systolic pressure gradient >20 mmHg across the lesion
Post stenotic dilatation of the renal aery
1b
single
B i.e. Presence of collaterals
Radiology
null
1debc3e3-2d02-4055-b2e1-a49d8ea312b5
Which of the following lies lateral to sheath of femoral hernia?
Femoral aery
lateral cutaneous nerve of thigh
Femoral vein
Femoral nerve
2c
single
Femoral vein lies lateral to sheath of femoral hernia.Femoral sheath - funnel shaped sleeve of fascia enclosing upper 3-4 cm of femoral vessels. The sheath is divided into three compaments by septa- Lateral compament - femoral aery and femoral branch of genitofemoral nerve Intermediate compament- femoral vein Medial co...
Anatomy
Lower limb 1
7132274a-faee-4d43-a48b-9c9e9568cc1e
The 5α reductase inhibitor that has been found to be effective both in benign prostatic hypertrophy and male pattern baldness is:
Flutamide
Finasteride
Prazosin
Minoxidil
1b
multi
null
Pharmacology
null
ab70d7e7-dac3-4527-be68-8eaff74a6fd7
Iron and folic acid supplement during pregnancy:
500 mg iron +100 meg folic acid
100 mg iron + 500 mcg folic acid
100 mg iron +100 meg folic acid
20 mg iron +100 meg folic acid
1b
single
Ans. (b) 100mg iron + 500mcg folic acidRef: D.C. Dutta 8th ed. / 241* Adult iron+folic acid tablet given in pregnancy: 1 tab/ day x 100 days* Kids iron+folic acid tablet given: 1 tab/day x 100 days per year- 0 to 5 years of age.Iron and Folic acid tablet content IronFolic acidAdult tab100mg500mcgKids tab (l/5th)20mg100...
Gynaecology & Obstetrics
Diet in Pregnancy
d0f14d2e-5dc1-4de3-915f-28c6e1e4060d
Carvallo's sign is seen in
Tricuspid stenosis
Mitral stenosis
Aoic stenosis
Aoic regurgitation
0a
multi
Ref Harrison 19 th ed pg 1548 A prominent RV pulsation along the left parasternal region and a blowing holosystolic murmur along the lower left sternal margin, which may be intensified during inspiration (Carvallo's sign) and reduced during expiration or the strain phase of the Valsalva maneuver, are characteristic fin...
Medicine
C.V.S
67bcc5c3-13c7-4c58-8295-96148dbc9fdb
A newborn baby who was apparently healthy at bih develops aspiration pneumonia in the first two days of life. All attempts to feed the infant cause it to cough and choke. Which of the following abnormalities is the most likely cause of the infant's difficulties?
Bronchogenic cysts
Congenital pulmonary cysts
Posterior detion of the tracheoesophageal septum
Pulmonary immaturity
2c
multi
The infant probably has esophageal atresia, which is typically caused by posterior detion of the tracheoesophageal septum. Attempts at feeding cause fluid to spill into the trachea, and secondarily cause aspiration pneumonia. Emergent surgical correction is usually required. Bronchogenic cysts are centrally located cys...
Pediatrics
null
fa625f89-2e09-42f4-80e4-bfbeb951fd70
Under the Indira Gandhi National Disability Pension Scheme, amount of monthly pension is:
Rs. 200
Rs. 450
Rs. 500
Rs. 600
0a
single
Under the Indira Gandhi National Disability Pension Scheme, amount of monthly pension is Rs. 200 for BPL persons aged between 18 to 59 years with multiple disabilities. Ref: Health policies and programmes in India, D.K. Taneja 11th edition page: 393
Social & Preventive Medicine
null
77295292-d28a-43fd-a1f8-79d4ddadb539
Epigenetic deals with genetic modifications that do not alter the sequence of DNA. All of the following can detect epigenetic modification except:
HPLC
Methylation specific PCR
Bisulphite method
ChIP on Chip
0a
multi
Ans. a. HPLC (Ref: Robbins 9/e p180, 319-320 8/e p180-181)Methylation specific PCR, Bisulphite method and ChlP on Chip can detect epigenetic modification but not the HPLC.'Epigenetics is defined as the study of heritable chemical modification of DNA or chromatin that does not alter the DNA sequence itself Examples of s...
Biochemistry
Molecular Biology Techniques
404aed9d-7bb7-4437-aa22-432f9fd368cf
Cutaneous sign of diabetes mellitus are all except
Necrobiosis lipoidica
Carotinosis
Shin spots (granuloma annulare)
Angiokeratomas
3d
multi
Ans: d (Angiokeratomas)Ref: IADVL, 3rd ed. vol. 2 pg. 1369- 1371Angiokeratoma corporis diffusum is a manifestation of Fabry's disease. All others are dermatological manifestations of diabetes mellitus.Skin manifestations of diabetis mellitus: Diabetic dermopathy Pigmented pretibial papules Shin spots Necrobiosis lipoid...
Skin
Miscellaneous
d8c67c14-63a4-4fb2-b360-b301b0e803ab
Recurrent aboion occurs in a woman, USG abdomen shows a non-echoic region in the central pa of the uterus. What is the probable diagnosis
Arcuate uterus
Septate uterus
Bicornuate uterus
Unicornuate uterus
1b
single
Septate uterus is most common It causes about 25% of spontaneous first trimester aboions 6% second trimester aboions Ref: Shaw Gynecology 17 e pg 72.
Gynaecology & Obstetrics
Congenital malformations
056c803e-5f6e-49c9-b17f-392735994496
If somebody develops resistance to INH, patient will develop simultaneously resistance to which drug?
Streptomycin
Rifampicin
Ethambutol
Pyrazinamide
1b
single
Ref: KD Tripathi, 7th ed. pg. 767* Rifampicin is considered as effective as isoniazid. This agent is active against slow and intermittently dividing bacterium (spurters).* If someone develops resistance to INH, they are most likely to develop resistance to rifampicin as well.* In MDR-TB, there is resistance to INH and ...
Pharmacology
Anti Microbial
ac8446c1-742b-4dcd-ac1d-026bb92a2538
Exotropia occurs due to
Third nerve palsy
Optic neuritis
Abducens injury
Papilloedema
0a
single
Answer- A. Third nerve palsyCauses and associations ofexotropia (Divegent squint)Third nerve palsyCongenitalPrevious strabismus surgeryThyroidophthalmopathyIatrogenic trauma following retinal detachment surgery
Ophthalmology
null
96621723-f722-4e8d-93a1-e62e0a39fed4
Urethritis in males is not caused by:
H. ducreyi
Trichomonas
Chlamydia
Gonococcus
0a
single
Hemophilus ducreyi causes soft sore/chancroid. Chocolate agar withIsoVitale Xis used for its culture. Infectious causes of urethritis- Neisseria gonorrhoeae Chlamydia trachomatis Trichomonas vaginalis Mycoplasma genitalium Herpes simplex virus Adenovirus
Microbiology
NEET Jan 2020
94eb2c5c-47e3-498b-b844-6d662014c143
Snowstorm appearance of knee joint with multiple loose bodies is seen in?
chondromalacia patellae
Ewings sarcoma of knee joint
Fracture involving articular surface
Synovial chondromatosis
3d
single
ANSWER: (D) Synovial chondromatosisREF: The Journal of bone and joint surgery: British volume: Volume 71, Pages 549-912, http:// www.springerlink.com/content/17m54n357304205m/Snowstorm knee:Seen in Synovial chondromatosisTraumatic etiologyJoint effusionNumerous brilliant white rice-grain size free bodies in arthroscopy...
Orthopaedics
Synovial Chondromatosis
24c528bb-2715-43d4-aa2c-e723e13eefe1
Treatment of metastatic disease in retinoblastoma is –
Chemotherapy
Enucleation
Radiotherapy
Cryo
0a
single
Treatment of choice for metastasis is chemotherapy.
Ophthalmology
null
52960709-acbb-403b-a468-8c74bfede83b
Absolute contraindication to ECT is:
Glaucoma
Brain tumor
Aoic aneurism
MI
1b
single
There are no absolute contraindications for ECT. Earlier, raised intracranial tension and space occupying lesions were considered as absolute contraindications, hence the best answer here is brain tumor.
Psychiatry
Miscellaneous
ca6ac6e2-e13f-438d-a28f-a89716bff6a0
The various habits of the lips can be divided into following, except:
Lip sucking
Lip thrust
Lip insufficiency
None of the above
3d
multi
The various habits of the lips can be divided into following: Lip sucking  Lip thrust Lip insufficiency
Dental
null
fbb3deb9-d186-4fca-a2f6-c683691a77b6
Xanthoproteic reaction is due to the formation of
Trinitrophenol
Mononitrophenol
Nitric acid
Pyrocathechol
0a
single
Nitric acid is a powerful oxidising agent and reacts with organic matter to produce trinitrophenol, liberating nitrogen monoxide (xanthoproteic reaction).
Forensic Medicine
Toxicology - 1
336d6710-2c3b-464c-b745-316ef660b7d4
What is the paial pressure for carbon-di-oxide in the expired air?
0.3 mm Hg
158 mm Hg
40 mm Hg
32 mm Hg
3d
single
Paial pressure of CO2 in expired air (PE CO2) - 32 mm Hg Carbon-di-oxide: Paial pressure of CO2 in inspired air (Pi CO2) 0.3 mm Hg Paial pressure of CO2 in alveolar blood (PA CO2) 40 mm Hg Paial pressure of CO2 in expired air (PE CO2) 32 mm Hg.
Physiology
null
fd3b4865-96ee-4346-b8f8-46f878075362
Marker for malignant melanoma is-
Cytokeratin
MBN-45
Alpha FP
S 100
3d
single
S 100
Unknown
null
b7a1e9ec-cfa6-451b-bb40-83af2b9e55c9
A 62 year old male patient presented with signs and symptoms of stroke. MR angiography revealed thrombus in the posterior cerebral aery. All of the following structures may be affected by the lesion except
Choroid plexus of III ventricle
Midbrain
Pons
Lentiform nucleus
2c
multi
The poserior cerebral aery (PCA) does not supply the pons The branches of the posterior cerebral aery are : Coical branches Occipital lobe- Visual coex Temporal lobe- medial and inferolateral surfaces Central branches Thalamus Subthalamus Lentiform nucleus Midbrain Pineal gland Superior and inferior colliculi Medial an...
Anatomy
Brain
a111b250-b7aa-4349-b008-b44985b375df
Features of Ankylosing spondylitis (AS) include all of the following EXCEPT:
Fibrous ankylosis is pa of pathogenesis of AS
Bony ankylosis is pa of pathogenesis of AS
Roos test is used to test for Sacroilitis
Marginal syndesmophytes are seen on X-ray
2c
multi
FEATURES of ankylosing spondilitis- enthesitis and this ultimately leads to joint ankylosis Both bony as well as fibrous ankylosis occurs in AS Marginal syndesmophytes are seen on X-ray Roos test is used for thoracic outlet syndrome.
Orthopaedics
Metabolic disorders - 1
b00b9bcf-ea36-4896-b68a-43c968c0a12a
Wood&;s lamp is made up of -
9% nickel oxide with 6% BuSO4
9% nickel oxide with 9% BuSO4
% nickel oxide with 6% BuSO4
9% nickel oxide with barium silicate
3d
single
WOOD'S LAMP Hand held device used to diagnose various dermatological conditions. It is a mercury vapour long wave,ultraviolet lamp with an inbuilt wood's filter made of barium silicate with 9% nickel oxide. Opaque to all wavelengths except those between 320 nm and 400 nm with a peak at 365 nm.Flourescence occurs when w...
Dental
miscellaneous
560baa5c-aee5-47ee-b496-e73dbf07061c
Method used for acid fast staining -
Robertson's method
Ziehl Neelsen
Silver imprignation method
Dark ground illumination
1b
single
Ans. is 'b' i.e., Ziehl Neelsen Acid fast stainingo After staining with aniline dye, acid fast organisms resist decolourisation with acids,o Method most commonly used is modified Ziehl Neelsen.Smear stained by carbolfuschin|Decolourization by 20% sulphuric acid|Counterstaining by methylene blueAcid fast organismsNon ac...
Microbiology
Culture media and method
d9e0f6a9-d329-4d53-a29b-6aaecd7b87b0
Wof are components of Waldeyer&;s ring
Lingual tonsil
Nasopharyngeal tonsil
Tubal tonsil
All of the above
3d
multi
WALDEYER'S RING Scattered throughout the pharynx in its subepithelial layer is the lymphoid tissue which is aggregated at places to form masses, collectively called Waldeyer's ring. The masses are: 1. Nasopharyngeal tonsil or the adenoids 2. Palatine tonsils or simply the tonsils 3. Lingual tonsil 4. Tubal tonsils (in ...
ENT
Pharynx
36808fb1-0369-42af-8c61-c9fdf99315cd
The embrasure areas in the following areas are continuous
Labial and Lingual
Lingual and Occlusal
Incisal and Occlusal
Labial and Occlusal
0a
single
null
Dental
null
5568012e-7fa4-4a54-b893-9539140e661d
Lysine is deficient in:
Maize
Wheat
Fish
Egg
0a
single
Maize
Social & Preventive Medicine
null
bda9fc2c-5048-4457-8da6-25ff247f3785
Treatment of choice in a postmenopausal lady with atypical endometrial hyperplasia is ;
Estrogens
Hysterectomy
Progestogens
Radiotherapy
1b
single
Hysterectomy
Gynaecology & Obstetrics
null
865e224d-6ed4-466d-a3f1-3782175cb1d7
During angiogenesis recruitment of pericytes and peri-endothelial cells is due to -
VEGF&PDGF
TGF, VEFG& PDGF
VEGF, IL-2, IL-6
Angiopoietins, TGF & PDGF
3d
single
Angiogenesis o Blood vessels formation in adults is known as angiogenesis or neovascularization. It can occur by two ways:- 1. Angiogenesis from pre-existing blood vessels The major steps in this process are i. Vasodilatation by NO, and VEGF-induced increased permeability of the pre-existing vessel. ii. Proteolytic deg...
Pathology
null
582e2447-317b-4a3d-b1fb-d78b8996026c
Basal cell carcinoma is seen in most commonly in which pa of the eyelid?
Upper medial
Upper lateral
Lower medial
Lower lateral
2c
single
(Refer: AK Khurana Comprehensive Ophthalmology, 6th edition, pg no. 384)*Basal cell carcinoma is the commonest malignant tumor to the lids (90%) usually seen in elderly people *It is locally malignant and involves most commonly lower lid (50%) followed by medial canthus (25%), upper lid (10-15%) and outer canthus"Basal...
Ophthalmology
Ocular motility and squint
1ea9eb09-a49d-4b71-8574-b62ffc2c7d2e
Field instrument used to measure bih weight:-
Salter's spring balance
Electronic weighing scale
Mass produced balance scale
Roberval balance
0a
single
- Field instrument to measure bih weight is Salter's Spring balance (kind of sling balance on which child is hung) - Average bih weight = 2.8kg - According to WHO, Low bih weight = < 2.5kg Very Low bih weight = < 1.5 Kg Extremely Low bih weight = < 1 Kg - Bih weight Doubles by 5 months Triples by 12 months Quadruples b...
Social & Preventive Medicine
Paediatric Care in RCH: BW, BL, PEM, Breast Feeding
5be2b87e-b926-442e-849c-61f186610c4a
In a drive for swachta abhiyaan, few group of young social activist markers cleaned sewers, after that they complain of fever, headaches. On examination, a non-catalase, non-glucose fermenting organism is isolated. Which of the following is most likely responsible:
Pseudomonas
Leptospira
Chlamydia
Actinomyces
1b
single
Leptospirosis Leptospira organisms are found in damp environments and affect people working there, like Stagnant water (sewer workers) Wet soil (agricultural workers) Mine workers Infected person can develop mild febrile illness, headache to jaundice and renal failure. Human acts as an end host of these organisms.
Microbiology
null
1acbff0e-52ea-4563-976a-f34b6e7bcd7e
In the perspective of the busy life schedule in the modern society, the accepted minimum period of sexual cohabitation resulting in no offspring for a couple to be declared infeile is:
One year
One and a half-year
Two years
Three year
0a
single
90% of couple who are cohabiting for at least one year with out contraception will have a conception. This is on monthly conception rates of 20 - 25 % in normal young couples attempting pregnancy.
Gynaecology & Obstetrics
Infeility (Eggs'plantation!)
c3e6d311-90e8-417d-86c1-34c36879ca92
What is the percentage of immunoglobulins present in proteins?
5%
10%
15%
20%
3d
single
Immunoglobulins constitute 20 to 25% of total serum proteins. Based on physiochemical and antigenic differences, five classes of immunoglobulins have been recognized: IgG, IgA, IgM, IgD, and IgE.(Ref: Ananthanarayan 9th edition, p93)
Anatomy
All India exam
2d4e0e42-cba5-4600-b636-6465edb2f23b
Perinatal mortality is expressed in terms of –
Deaths/1000 total births
Deaths/1000 live births
Deaths/10000 total births
Deaths/10000 live births
1b
single
null
Social & Preventive Medicine
null
563754d0-4aef-4c16-b2ed-ef222d6c6626
A male neonate born with protrusion over anterior abdominal wall .This protrusion was diagnosed to be omphalococle. how do you distinguish this protrusion from gastroschisis and say it as omhalocolle, because in an omphalocorle
Not covered by a sac
Associated with some or complete malrotation of bowel
A detect in abdominal musculature
Associated with an umbilicus attached to the abdominal walk musculature.
1b
multi
null
Surgery
null
d54a7b8c-7eb0-42c7-97a4-4875c99fa08d
Which of the following is not a feature of hallucination: September2010
It can occur in any sensory modality
It is independent of will of observer
It is defined as perception occurring without external stimulation
Always pathological
3d
multi
Ans. D: Always pathologicalA hallucination, in the broadest sense of the word, is a perception in the absence of a stimulus.In a stricter sense, hallucinations are defined as perceptions in a conscious and awake state in the absence of external stimuli which have qualities of real perception, in that they are vivid, su...
Psychiatry
null
08c77273-8068-424b-9cde-efeb2d4436fd
Tapir Nose is Complication of
Atropic Rhinitis
Rhinosporidiosis
Rhinoscleroma
Syphilis
2c
single
null
ENT
null
c9ed49a3-a6a1-4b0a-a9c6-817ec562ac34
A child with 3 years age presents with weakness with Hb level <5 gm/100 ml. History of joint swelling and bleeding spot were present. What would be causative organism?
Hook worm
Round worm
Whip worm
Pin worm
0a
single
Signs and Symptoms Most children with hookworm infections have no signs or symptoms. However, especially when the infection is long term, it can cause iron deficiency and anemia (low red blood cells) because of bleeding from the bowel wall where the worm is attached. Other symptoms include mild diarrhea and stomach cra...
Pediatrics
Genetic and genetic disorders
4130a05e-eb37-434b-bedb-93fdbe6d68d1
For the following side effects, select the most likely medication to cause them.Disinterest in food with protein/calorie malnutrition.
selective serotonin reuptake inhibitors (SSRIs)
mineral oil
diuretics
INH
0a
single
Tricyclic antidepressants and SSRIs are both effective treatments for depression, but their side-effect profiles are different. Tricyclics can promote weight gain while weight loss is more common with SSRIs.
Medicine
Drugs
829b3331-e0cb-4fdd-b2a1-a37c2bcdb44b
Second constriction of oesophagus lies at the level of
Where aortic arch crosses
Bronchi
Pharynx
Where esophagus pierces the diaphragm
0a
single
(A) (Where aortic arch Crosses) (282-BDC-16(tm))CONSTRICTIONSNormally the oesophagus shows 4 constrictions at the following levels1. At its beginning 15 cm/6 inch form the incisor teeth where it is crossed by cricopharyngeus muscles2. Where it is crossed by the aortic arch, 22,5cm /19 inch from the incisor teeth3. Wher...
Anatomy
Thorax
7b2dfe85-f51c-48c2-b03d-da9e2d0402df
Magnitude of action potential is determined by:
Na+
Mg++
K++
Ca++
0a
single
Maximum magnitude is determined by equilibrium potential of Na+ ion.
Physiology
null
dcff52be-fb5b-4119-9e1e-12ed61aa183a
Indications of prophylactic cholecystectomy are all except
Diabetes
Hemoglobinopathy
Gallstone size >3 cm
Porcelain GB
0a
multi
Diabetes Mellitus Patients with diabetes may have a higher incidence of gallstones from the indirect effects of the metabolic syndrome, obesity, and a family history of gallstones No data show worse evolution of asymptomatic cholelithiasis in diabetes, and prophylactic cholecystectomy in asymptomatic gallstones carrier...
Anatomy
G.I.T
8eb47f53-07d8-4291-a3d3-8cda69a612af
The source of apo-E and apo C-II for the chylomicrons is:
VLDL
IDL
LDL
HDL
3d
single
Newly secreted or "nascent" chylomicrons and ApoB-48 apolipoprotein. HDL acts as a reservoir of lipoproteins and provide ApoE and ApoC to nascent chylomicrons to form mature chylomicrons.
Biochemistry
Lipoproteins
3ddc3460-5a43-4ec3-a662-d07e2e54b9bb
All of the following are true about loop diuretics except:
They are called as "high ceiling" diuretics
They act on Na+.K+.2Cl- symporter
They can cause hyperuricemia
Loop diuretics lead to hypercalcemia and hypomagnesimia
3d
multi
Loop diuretics lead to hypocalcemia and hypomagnesimia.
Pharmacology
null
bfab5237-0add-4277-91a5-b99c7f9f2846
Panic attack is associated with a disturbance in all of the following neurotransmitters except -
Serotonine
Glutamate
GABA
Dopamine
1b
multi
The major neurotransmitter systems that have been implicated in panic disorder are those for norepinephrine, serotonin and GABA. "An abnormal dopaminergic function has been hypothesized to be involved as an etiological factor in panic disorder as well as migraine"
Psychiatry
null
50f67ace-0c4b-435b-89bc-e827d452a3d2
A 6 year old boy has been complaining of headache, ignoring to see the objects on the side for 4 months. On Examination, he is not mentally retarded, his grades at school are good & visual acuity is diminished in both the eyes, visual chaing showed significant field defect. CT scan of the head showed suprasellar mass w...
Astrocytoma
Craniopharyngioma
Pituitary adenoma
Meningioma
1b
multi
B i.e. Craniopharyngioma
Radiology
null
69edd63e-db0c-457e-b9d2-fe3487f00ed5
All-trans-retinoic acid is used in treatment of
Acute promyelocytic leukemia
A.L.L
CML
Transient myeloproliferative disorder
0a
multi
Ref: Harrison 17th/389,447 All-trans-retinoic acid is used in the treatment of acute promyelocytic leukemia.
Pharmacology
Chemotherapy
93332766-20ca-4544-86e5-3c56cda3fb0f
All of the following are the risk factors for carcinoma gallbladder except:
Primary sclerosing cholangitis
Porcelain gallbladder
Multiple 2 cm gallstones
Choledochal cyst
2c
multi
Risk Factors of Carcinoma Gallbladder Gallstones >3 cm Porcelain gallbladder Anomalous pancreatobiliary junction Choledochal cysts Adenomatous polyps Primary sclerosing cholangitis Obesity Salmonella typhi infection
Surgery
Gallbladder
e18bd66d-8c4d-4358-89b0-00301f0a700e
Chances of blindness in diabetic patient as compared to non-diabetic patient is ?
5 times
10 times
15 times
25 times
3d
single
Answer- D. 25 timesThe gravity of this problem is highlighted by the finding that individual with DM are 25 times more likely to become legally blind than individuals without DM.
Medicine
null
531c4517-9ab0-4a28-bdcc-3a5912e257a6
Tyrosine is required for the synthesis of all of the following except:
Melatonin
Epinephrine
Norepinephrine
Thyroxine
0a
multi
Ans. A. MelatoninMelatonin is a hormone, synthesized by pineal gland. The amino acid required is tryptophan. It is also called N-acetyl 5- methoxy serotonin. Melatonin is involved in circadian rhythms.Epinephrine, Nor-epinephrine and thyroxine are all synthesized by Tyrosine.
Biochemistry
Proteins and Amino Acids
929b389f-e394-4d2f-9d48-91db03b96b06
Impulses generated in the taste buds of the tongue reach the cerebral cortex via the:
Thalamus
Internal capsule
Cervical spinal nerve
Trigeminal nerve
0a
single
Functions of the Thalamus: The main functions of the thalamus are as follows: It is a sensory integration and relay station of all the sensory pathways except for the olfactory pathway which is projected directly to the cerebral cortex without being relayed in the thalamus. The impulses from taste buds of tongue reach...
Anatomy
null
fc439d5e-6a9b-462d-8527-232aec8fcbc5
Sinusitis in children is commoner in which sinus:
Frontal
Maxillary
Ethmoid
Sphenoid
2c
single
The commonest sinus involved was ethmoidal in children and mixed sinus pathology in adults. The majority of patients responded to medical treatment. CONCLUSION: Orbital complications of sinusitis are commoner in children than adults and have orable prognosis.
ENT
null
5248b4b5-2deb-4adc-ab4d-d41c31102213
Most common of all psychiatric disorders are -
Anxiety disorder
Schizophrenia
Depression
Mania
0a
multi
Ans. is 'a' i.e., Anxiety disorder o Anxiety disorders are the most common of all psychiatric illnesses. According to DSM-IV-TR following are anxiety disorder :-Panic disorder with or without agoraphobia.Agoraphobia with or without panic disorder.Specific phobia.Social phobia.Obsessive - compulsive disorder.Post trauma...
Psychiatry
Generalized Anxiety Disorder
b8a1b4f3-ca06-47fa-b855-c85bae70ea96
What is the sequence which a retrovirus follows on entering a host cell -
RNA-DNA-RNA
RNA-DNA
DNA-RNA
DNA-RNA-DNA
0a
single
when virus infect a cell viral RNA is transcribed by enzyme first into ssDNA then to dsDNA REF:MICROBIOLOGY ANANTHA NARAYANAN NINTH EDITION PAGE.571
Microbiology
Virology
3f55b982-8941-49d5-bd19-ef0fd3cc1f91
The most appropriate drug used for chelation therapy in beta thalassemia major is -
Oral desderrioxamine
Oral deferiprone
Intramuscular EDTA
Oral Succimer
1b
single
Ans. is 'b' i.e., Oral deferiprone Desferrioxamine is poorly absorbed from GIT and hence not recommended for oral administration, although it continues to be the chelating agent of choice for parentral administration. o Deferiprone is a recently introduced orally active iron chelating agent meant to be used as an alter...
Pharmacology
null
6ac82513-491e-4e32-aaed-b2958813a286
Which one of the following is true about follicular carcinoma of thyroid?
Is the most common thyroid cancer
Is readily diagnosed by FNAC
More commonly spreads through hematogenous route
Is commonly seen as multifocal
2c
multi
follicullar carcinoma is not a common thyroid cancer,occurance is 10-15%. it spreads mainly through blood into bones,lungs ,liver FNAC is inconclusive , because capsular and angioinvasion which can&;t be detected by FNAC It is a well localised, nonmobile, soft, fluctuant and pulsatile secondaries in the skull ref ;(pag...
Surgery
Endocrinology and breast
db01c4bb-8f25-44df-ba91-db4327751497
ORS plus Zinc
Reduces infection
Antispasmodic
Reduces duration of diarrhea
Enhance sodium absorption
2c
single
Zinc supplementation with ORS therapy reduce Duration of diarrhea Severity of acute and persistent diarrhea Volume of diarrhea
Social & Preventive Medicine
Miscellaneous
05c54937-6292-4fe2-871c-1fa911582938
Torsade-de-pointes is caused by -
Hypermagnesemia
Metabolic acidosis
Hypomagnesemia
Metabolic alkalosis
2c
single
null
Medicine
null
6a9fb89e-a996-4f79-b0a3-87c0f1ff73d8
Tooth with hyperemia will give response to electric pul tester?
Low reading than control teeth
High reading than control teeth
Electric pulp testing is not very significant in hyperemia.
False negative response.
0a
multi
null
Dental
null
63d27494-2c11-4570-8d16-ec5141691843
Drug of choice for preventing Fetal Toxoplasmosis infection during pregnancy is -
Pyrimethamine
Sulfadiazine
Spiramycin
Pyrimethamine + Sulfadiazine
2c
single
Ans. is 'c' i.e., Spiramycin * Classic congenital toxoplasmosis is characterized by the tetrad described by Sabin in 1942: chorioretinitis, hydrocephalus, intracranial calcification and convulsion.Signs such as intracranial calcification, microcephaly, hydrocephalus, and severe intrauterine growth restriction strongly ...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
8543fcc9-1cc2-4c3e-b243-40831de2cd2e
SIADH true is all except -
Serum Na can be less than 135 meq\/1
Urine sodium is normal or slightly low
Vaptans are new FDA approved drugs for its Rx
Water loading test can be used
2c
multi
Water retention also occurs in the syndrome of inappropriate secretion of ADH (SIADH). In this condition, an endogenous source of ADH (either cerebral or tumour-derived) promotes water retention by the kidney in the absence of an appropriate physiological stimulus (Box 16.13). The clinical diagnosis requires the patien...
Medicine
Endocrinology
decdf4d8-8556-4421-80e0-acd8c8c1baf5
Shoe polish like smell is seen in:
Mercaptans
Lacquer
Paraldehyde
Nitrobenzene
3d
single
Ans. d. Nitrobenzene (Ref: Reddy 33/e p507; Industrial Hygiene and Toxicology. General Principles/p 174)Shoe polish like smell is seen in Nitrobenzene."Nitrobenzene is an oily yellow to yellow-brown liquid that smells like bitter almonds or shoe polish. Nitrobenzene dissolves only slightly in water and easily in other ...
Forensic Medicine
Forensic Toxicology - Concepts, Statutes, Evidence, and Techniques
08f630be-f2c9-469b-8ca5-39232e75f2b7
A woman assaulted by neighbor was brought to you in the emergency depament with fracture of middle tooth. Injury was extended medially to the mouth and there was also contusion to bilateral leg. What is the nature of the injury
Grievous injury
Simple injury
Dangerous injury
Assault
0a
multi
Ans. a. Grievous injury Fracture or dislocation of a bone or a tooth constitute Grevious injury. Grevious Injury (Sec 320 IPC) Emasculation Permanent privation of either eyedeg Permanent privation of either ear Privation of any member (pa, organ or limb) or joint Permanent disfiguration of head or facedeg Fracture or d...
Forensic Medicine
null
426531cb-500e-4dcb-9c39-e17f28ca0e1b
True statement about Rheumatic fever in childrena) Polyarthritisb) Caused by α hemolytic streptococcic) Most common valve involvement is Mitrald) Erythema marginatum is common in face
bc
cd
ac
ab
2c
multi
null
Medicine
null
1f068645-17fb-4fa6-8aa5-95d0b07875f4
Protein requirement for 2 year old child (per day)-
10 gm
15 gm
20 gm
25 gm
2c
single
Ans. is 'c' i.e., 20 gm GroupageProtein/davInfant0-6 month6-12 month2.05/kg1.65,'TegChildren1-3 year4-6 year7-9 year10-12 year13-15 gm22 gm30 gm41 gm54 gm65-70 gm
Pediatrics
Nutritional Requirements
160f1ef7-451b-4362-bd71-97c72fcc8140
The cardiac silhouette can have an "egg on side" appearance in
VSD
PDA
TOF
Transposition of Great Vessels
3d
single
Transposition of great vessels (TGA) is defined as aoa arising from the right ventricle and pulmonary aery from the left ventricle. In patients with TGA, the oxygenated pulmonary venous blood recirculates in the lungs whereas the systemic venous blood recirculates in the systemic circulation. The pulmonary aery saturat...
Pediatrics
C.V.S
48012e3a-8b20-4a99-adb1-44ffecbc5331
Characteristic features of benign prostate hyperophy include all of the following except :
Increased trabeculations in bladder
Enlargement of lateral lobes of prostate
'J' shaped/ 'fish hook' distal ureters
Bilateral hydronephrosis
1b
multi
Radiological features of BPH: 'Slit-like' elongated and compressed urethra Smooth filling defect/ indentation in bladder floor Periurethral and subvesical enlargement is very pronounced may produce rounded defect in floor mimicking Foley's balloon. Floor of bladder elevated and trigone pushed upwards, with distal urete...
Radiology
Genitourinary radiology
dce5e747-b0ce-4ffc-9aee-0594fb49832b
Oakley-Fulthorpe procedure is:
Single diffusion in one dimension
Double diffusion in one dimension
Single diffusion in two dimensions
Double diffusion in two dimensions
1b
single
*Various immunodiffusion test *Single diffusion in one dimension - Oudin procedure *Double diffusion in one dimension - Oakley fulthorpe procedure *Single diffusion in two dimensions - Radial immunodiffusion *Double diffusion in two dimensions - Ouchterlony procedure
Microbiology
Immunology
f90c434f-e5b9-4ea7-9428-545613b30160
Priapism is seen in
Rat poisoning
Arsenic poisoning
Sildenafil poisoning
Cantharide poisoning
3d
single
The Spanish fly (Cantharis vesicatoria, blister beetle) is 2 x 0.6 cm in dimensions. Active principle: Cantharidin.Action: It is locally irritant and nephrotoxic agent Priapism in males and aboion in pregnant females may occur. The patient becomes prostrated with convulsions, and coma preceding death. TreatmentGastric ...
Forensic Medicine
Poisoning
5688761c-3708-47e0-b31f-7dde6725f9cc
Gene duplication plays an impoant role in the evolution of aEUR'
>m Rna
>r Rna
>t Rna
>hn Rna
0a
single
mRNA (most likely) Gene duplications are impoant forces of genome evolution which change genome size and lead to the evolution of new gene functions. Gene duplication (or chromosomal duplication or gene amplification) is any duplication of a region of DNA that contains a gene; it may occur as an error inhomologous reco...
Biochemistry
null
6b95a78c-0e68-406d-b046-a9a2de340f73
Upper motor neuron lesion is characterized by:March 2013
Weakness and Spasticity
Fasciculations
Rigidity
Localized muscle atrophy
0a
single
Ans. A i.e. Weakness and spasticity
Medicine
null
a8e09095-c640-4ad2-95b0-10d8a7addf3c
Surgical staging of ovarian Ca all done except;
Peritoneal washing
Peritoneal biopsy
Omental biopsy
Palpation of organs
2c
multi
<p> Steps of surgical laparotomy in ovarian carcinoma; Ascites and peritoneal washing for cytology Systematic exploration of abdomen and pelvis Biopsy of suspicious areas Sampling of diaphragm Infracolic omentectomy Pelvic and paraoic node evaluation Careful documentation of operative findings Reference : textbook of g...
Gynaecology & Obstetrics
Gynaecological oncology
b7f8aa21-0452-4046-9aa2-564858bcc8ac
Lardaceous spleen is due to deposition of amyloid in:
Sinusoids of red pulp
White pulp
Pencillary aery
Splenic trabeculae
0a
single
Amyloidosis of the spleen may be inapparent grossly or may cause moderate to marked splenomegaly (up to 800 g). Two patterns of deposition is seen:- The deposits limited to the splenic follicles, producing tapioca-like granules on gross inspection, designated sago spleen. The deposits involves the red pulp,Fusion of th...
Pathology
Amyloidosis
fda98ccd-14a1-443b-af07-6b913c213125
Wide pulse pressure is seen in
Beri beri
Cardiac tamponade
Diarrhea
Aortic stenosis
0a
single
Wide pulse pressure is when SBP increases by more than 50%. It is seen in: Aortic regurgitation  PDA Anemia Beri beri Hyperthyroidism  Fever Complete  heart block AV shunts
Medicine
null
609e8a20-afff-498a-ba3c-628539f52f87
The following virus can be grown only in suckling mice-
Coxsackie virus
Rhinovirus
Echovirus
Poliovirus
0a
single
Ans. is 'a' i.e., Coxsackie virus . It is necessary to employ suckling mice for the isolation of coxsackie viruses. . Inoculation is usually made by intracerebral, subcutaneous and intraperitoneal route. . Adult mice are not susceptible.
Microbiology
null
6063d451-2bd5-4845-b7b8-a96af73c5e26
Nephrocalcinosis is seen in all except :
Sarcoidosis
Distal A
Milk alkali syndrome
Medullary cystic kidney
3d
multi
Medullary cystic kidney Nephrocalcinosis Conditions associated with nephrocalcinosis are :- . Hyper ox aluri a . Hyperparathyroidism . Prolonged immobilization . Hypervitaminosis D . Hypophosphatemic rickets excessive bone destruction in metastatic . Coical necrosis malignancies (such as multiple myeloma) . Cushing syn...
Surgery
null
de407aa5-cffe-4942-b3e0-29f4fe42d610
Which of the following relaxes bronchial smooth muscles?
Cold air
Leukotriene
Ach
VIP
3d
single
Introduction. A major symptom of asthma is an excessive contraction of airway smooth muscle cells (SMCs) which results in airway hyper-reactivity. To allete this acute and chronic airway constriction, b-adrenergic agonists, that relax SMCs, are commonly administered Ref: guyton and hall textbook of medical physiology 1...
Physiology
Respiratory system
6f86c247-7bbf-466e-a661-d1cb8166c428
Progestase has to be replaced after :
1 year
5 years
3 years
6 months
0a
single
The US Food and Drug Administration (USFDA)-approved effective life is only 1 year. The contraceptive effectiveness of the progestase is similar to that of Cu IUDs; it reduces menstrual loss but has to be replaced every year.
Gynaecology & Obstetrics
Contraceptives
d774c3c1-1b99-4ab0-a11a-2bd0d7e324dd
Cholesterol is a(an)
Ester
Phospholipid
Sterol
Lipoprotein
2c
single
Ref: DM Vasudevan - Textbook of Biochemistry, 6th edition, page no: 146
Biochemistry
Metabolism of lipid
2c44b9bc-cd20-4d45-8316-ffa96090d427
Most common site of metastasis in skeleton ?
Femur
Tibia
Veebrae
Skull
2c
single
Ans. is 'c' i.e., Veebrae Metastasis Metastatic bone disease is the commonest malignancy of bones and is much more common than primary bone tumors. The commonest sites for bone metastases are veebrae (most common), pelvis, the proximal half of the femur and the humerus. Extremities distal to elbow and knee are least co...
Surgery
null
3bd36de6-f1e1-48e7-9aa7-801ed574996c
All are features of hyperparathyroidism except?
Increase serum calcium
Decreased serum phosphate
Diarrhea
Nephrocalcinosis
2c
multi
Hyperparathyroidism leads to increase PTH. PTH increases serum calcium by increasing dietary absorption of vitamin D3. It also ensures that the proximal convoluted tubule sta losing phosphate in urine leading to decreased serum phosphate. The increase in serum calcium leads to deposition of calcium in kidney parenchyma...
Medicine
Disorders of Parathyroid Gland
838cb05e-381c-4068-ac8d-48562f2537d8
FALSE statement about polyaeritis nodosa (PAN) is:
It is a necrotizing vasculitis of small and medium-sized muscular aeries
Involvement of the renal and visceral aeries is characteristic.
PAN does not involve pulmonary aeries and bronchial vessels
Granulomas, significant eosinophilia, and are not observed.
2c
multi
Polyaeritis nodosa (PAN) It is a multisystem, necrotizing vasculitis of small and medium-sized muscular aeries. Involvement of the renal and visceral aeries is characteristic. PAN does not involve pulmonary aeries, although bronchial vessels may be involved; Granulomas, significant eosinophilia, and an allergic diathes...
Pathology
null
e34e4075-74b5-468b-8bcd-aa72c8f9f08e
The neurotransmitter agent that is normally released in the SA node of the heart in response to increased blood pressure is:
Acetylcholine
Dopamine
Adrenaline
Noradrenaline
0a
multi
null
Pharmacology
null
17708270-9c5f-4627-b93e-4c208cd16d1f
A 60-year-old woman, Sridevi presents with a murmur suggestive of mitral stenosis and an echocardiography confirmed a mass attached to the fossa ovalis of the left atrial septum. What is the most likely diagnosis?
Cardiac myxoma
Endocarditis
Lymphoma
Metastatic cancer to the hea
0a
single
Atrial myxoma is the most common benign cardiac tumor. It usually presents with symptoms of valvular obstruction (mural or tricuspid valve). It is attached by a pedicle to the fossa ovalis of the left atrial septum. It is treated by resection.
Surgery
Thorax And Mediastinum
ebe49d4a-5da2-4e90-bf40-abcdb92486bf
The cardiac output can be determined by all except
Fick's principle
V/Q ratio
Echocardiography
Thermodilution
1b
multi
Methods to determine the Cardiac output Flowmeter Cardiometer -        Indirect method- Used in humans Fick’s principle method Indicator dilution method Thermodilution method Doppler echocardiography Cineradiography
Physiology
null
b61806f0-89b9-401c-ace3-632027592cd8
Headache is commonly seen with which anti-anginal drug?
Beta blockers
Nitrates
Trimetazidine
Potassium channel openers
1b
single
Nitrates produce headache because of vasodilatation of meningeal vessels. Ref katzung 12th ed.
Pharmacology
Cardiovascular system