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135
6316abad-e018-42b4-b9d7-b0b20e751322
Neural tube defect is an adverse effect of :
Valproate
Phenytoin
Diazoxide
None
0a
multi
null
Pharmacology
null
e0f43655-df98-48c9-81fa-9dd54f6190a3
Which of the following is an example of precipitation reaction?
Widal Test
Coomb's Test
Counter Current immunoelectrophoresis
Weil-Felix Test
2c
single
Precipitation is a method for detecting an antigen-antibody reaction. When antigen and antibody combine in the proper propoions, a visible precipitate is formed. Optimum antigen-antibody ratios can be produced by allowing one to diffuse into the other, most commonly through an agar matrix (immunodiffusion). Counterimmu...
Microbiology
null
6977737d-8eee-4d0e-ba77-195875ab70ef
Most common anomaly of upper urogenital tract is -
Uretero pelvic junction stenosis
Ectopic uretheral opening
Ureterocele
Ectopic ureter
0a
single
Ans. is 'a' i.e., Uretero pelvic junction stenosis o UPJ stenosis is most common abnormality in childhood and is more frequent in male children, characterised by narrowing usually on left side.o Overall, position & shape of kidney being most common one.o Horse shoe kidney is the most common and most frequently found re...
Pediatrics
Nephropathy
55a91596-924c-4110-8598-3df55624a477
Which of the following is not seen in papilledema: March 2009
Marked venous engorgement
Elevation of optic disc
Cotton wool spots
Prominent optic disc margins
3d
single
Ans. D: Prominent optic disc margin Signs of papilledema: Early and mild Papilledema - Subtle gray peripapillary halo - Normal radial optic nerve head disrupted and nerve fibers accentuated by grayish opacity - Concentric folds of the retinochoroid Moderate Papilledema - Borders of optic disc become obscure - Disc marg...
Ophthalmology
null
11e83a84-7980-409e-9b8a-fbe807af35c8
Name of mumps vaccine is -
Jeryl Lynn
Edmonshon zagreb
Schw'atz
Moraten
0a
single
Ans. is 'a' i.e., Jeryl lynn VaccineStrainso RubellaRA27/3o MeaslesEdomonston Zagreb strain (most common) Schwarts strain Mortaten straino MumpsJeryll Lynn straino Chicken poxOKA strainoBCGDanish 1331o JENakavam strain (MC), Beizing P3 strain, SA 14-14-2o Yellow fever17 Do MalariaSPf.66,Pf25o HIVmvA (modified vaccinia ...
Social & Preventive Medicine
Principles of Immunization and Vaccination
173e9c95-3647-4436-9f2d-ff7bdbe64bd6
Which of the following biochemical reaction is associated with substrate level phosphorylation?
Fumarate to malate
Succinate to fumarate
Succinyl CoA to Succinate
Acetoacetate to a-ketoglutarate
2c
single
Conversion of succinyl CoA to succinate is an example of substrate level phosphorylation in which a high energy phosphate is generated from the energy trapped in the thioester bond of succinyl CoA. Enzyme succinic thiokinase catalyses this step. In this reaction a molecule of GDP is phosphorylated into GTP and succinat...
Biochemistry
null
e0c41b18-03a7-46fc-903f-fd3996dc247a
The sputum examination under DTP is done when the patient present with -
Cough of 1-2 weeks duration
Persistent cough of 1-2 weeks duration
Hemoptysis
Chest pain
2c
single
<p> Hemoptysis Sputum examination under TB programme is done when patient presents with -cough more than 2 weeks. -fever with an evening rise. -hemoptysis. -unexplained weight loss. -reduced appetite. Park&;s textbook of preventive and social medicine,K.Park,21st edition,page no:392, 22nd edition,page no:396. <\p>
Social & Preventive Medicine
Communicable diseases
02eeaa43-9961-4e34-a188-220d30dd5a49
Which one of the following is not an objective of trituration?
Remove oxides from powder particle surface
Keep the amount of gamma-1 or gamma-2 matrix crystals to maximum
Pulverize pellets into particles to aid in attack by mercury
Achieve a workable mass of amalgam in minimum time
1b
single
null
Dental
null
1fad4ee6-7929-41f5-9b11-c136bcd25a6a
Largest branch of veebral aery is
Anterior spinal
Posterior spinal
Anterior inferior cerebellar
Posterior inferior cerebellar
3d
single
Anterior inferior cerebellar aery is a branch of Basilar aery
Anatomy
All India exam
21900172-c8a3-4d27-a63d-2314f81180ca
An orthopedician adducts the flexed hip and gently pushes the thigh posteriorly in an effort to dislocate the femoral head of a neonate. What is this maneuver called?
Galeazzi sign
Ortoloni test
Telescopic sign
Barlow test
3d
multi
D i.e. Barlow testRef: Nelson, Textbook of Pediatrics, 20th edition, page 3274Developmental Dysplasia of the Hip (DDH)Ranges from simple acetabular dysplasia, acetabular dysplasia plus subluxation to dislocation of the hip joint.Two major groups:Typical (otherwise normal individuals without defined syndromes or genetic...
Pediatrics
Musculo Skeletal Disorders
bc4ce38d-49d6-45c2-bbe6-c2e38cf2cbd1
True statement regarding ectopic pregnancy:
Serum progesterone >25 ng/ml exclude ectopic
p-hCG levels should be >1000 mlU/ml for earliest detection by TVS
p-hCG levels should be <1000 mlU/ml for earliest detection by TVS
Methotrexate is not used for treatment
0a
multi
If the serum beta hcg value is 1500 IU/L and an intrauterine pregnancy is not visualized in a TVS it is likely to be an ectopic .This is the level at which intrauterine gestational sac is seen and is called discriminatory zone (refer pgno:159 sheila 2 nd edition)
Gynaecology & Obstetrics
General obstetrics
a3dae7e5-8e85-4f5d-a4eb-42183b44ef59
The Vitamin A activity of beta-carotene compared to that of retinol is?
2-Jan
4-Jan
6-Jan
8-Jan
2c
single
Beta-Carotene (provitamin A): This is found in plant foods. lt is cleaved in the intestine to produce two moles of  retinal. ln humans, this conversion is inefficient, hence beta-carotene possesses about  one-sixth vitamin A activity compared to that of retinol. Reference: Satyanarayana- Biochemistry, 3rd edition, p...
Biochemistry
null
0043c505-6981-48a9-93d1-981bf8a8b272
Prinzmetal angina is-
Angina after extreme exertion
Caused due to atherosclerotic blockade
Caused due to spasm of artery
Calcium channel blockers not effective
2c
single
null
Medicine
null
19a2cadb-4995-4b8e-8068-0484bd4b09cf
Insulin causes all of the following except
Glycogenesis
Glycolysiis
Lipogenesis
Ketogenesis
3d
multi
Refer Katzung 11/e p 731 Insulin inhibits the formation of ketone bodies, therefore it's deficiency can result in diabetic ketoacidosis
Pharmacology
Endocrinology
c82a5657-0e2f-48c1-b32c-fb52e34d41ca
True statement about fatty acid:
Polyunsaturated FA is essential for membrane structure
Biologically arachidonic acid is essential to life
Hydrogenated vegetable oils contains Trans fatty acid
All
3d
multi
C, B, > A i.e. (Hydrogenated vegetable oils contains Trans fatty acid; Biologically arachidonic acid is essential to life >Polyunsaturated FA is essential for membrane structure)
Biochemistry
null
843ec470-bf55-43cb-a0f3-ffc1cb36a7a4
Which of the following can cause toxic megacolon in 36 year old lady?
Amoebic colitis
IBS
Ulcerative colitis
Viral diarrhea
2c
single
The hallmarks of toxic megacolon (toxic colitis), a potentially lethal condition, are nonobstructive colonic dilatation larger than 6cm and signs of systemic toxicity. The impoant etiologies of toxic megacolon include the following inflammatory causes: Ulcerative colitis Crohn colitis Pseudomembranous colitis The compl...
Surgery
null
4a18c6c4-b130-4c86-a39e-084215939d57
Percentage of cold nodules that becomes malignant are?
5%
15%
20%
40%
2c
single
ANSWER: (C) 20 %REF: Bailey and love 25th ed page 779See details of thyroid nodules in Surgery June 2011About 80% of discrete swellings are cold. The risk of malignancy is higher in "cold" lesions (20%) compared to "hot" or "warm" lesions (<5%).
Surgery
Evaluation of a Thyroid Nodule
e1445a54-b0a4-4afc-82c7-aa6c58974f7d
In a rural clinic, a 3 year old girl child is brought by her mother and is emaciated. Her Hb was 5g/ dl. The girls also had edema over her knees and ankle, with discrete rash on her knees, angles and elbows. The most likely worm infestation causing these manifestations is?
Hook worm
Round worm
Whip worm
Pin worm
0a
single
null
Microbiology
null
dd3fa834-1605-4610-9287-fe4ac868594c
Long acting beta agonist used once a day:
Salmeterol
Formoterol
Indacaterol
Terbutaline
2c
single
Ans. C. IndacaterolRef: Katzung's Basic and Clinical Pharmacology 13th/ed, p340ExplanationAns. c. Indacaterol Ref: Katzung's Basic and Clinical Pharmacology 13th/ed, p340Explanationb agonistFeatures* Albuterol (salbutamol)* Terbutaline* Metaproterenol* Pirbuterol* Metered-dose inhalers* Bronchodilation is maximal withi...
Pharmacology
Asthma
c1649806-fcfe-4eb8-b3f4-55482141fcdf
Essential for tumor metastasis is-
Angiogenesis
Tumorogenesis
Apoptosis
Inhibition of Tyrosine kinase activity
0a
single
Angiogenesis is the mechanism of formation of new blood vessels. It is very critical in establishing the metastasis at the new area. Basic Pathology, Robbins. Page no.: 194
Pathology
General pathology
68ffc131-c9b4-4bf2-93a7-5f3eb14f9ec6
Large dose of EDTA are used in carbonic anhydrase enzyme inactivation. The mechanism by which EDTA act is -
It chelates with the metal ions of the enzyme
It combines with the substrate and reacts with the enzyme
Combines with the substrate and doesn't react with the enzyme
Enzyme-EDTA complex can not be attached to substrate
0a
single
Ans. is 'a' i.e., It chelates with metal ions of the enzyme o EDTA is a chelating agent and it has already been explained that chelating agent has legands (reactive groups) for metal binding. o These ligands of chelating agent bind to metal ions and cause chelation. o EDTA binds to zinc ion of carbonic anhydrase and th...
Pharmacology
null
fe0a81e2-0291-4993-8ee7-1573bb3298cf
Drug contraindicated in hyperiglyceridemia
Fibrates
Simvastatin
Niacin
Cholestyramine
3d
single
Bile acid binding resins like cholestyramine causes increase in triglycerides and are thus contraindicated in patients with hyperiglyceridemia due to risk of development of pancreatitis. Statins - decrease LDL and increase HDL Niacin - decrease LDL and triglyceride, maximum increase in HDL Fibrates - decrease triglycer...
Pharmacology
Hypeension, Arrhythmias, Dyslipidemia
90d63165-ee18-4018-bd10-607595e2ab21
Culture media for transport of stools in suspected case of shigellosis -
Deoxycholate medium
Blood agar
Nutrient broth
Buffered glycerol saline
3d
single
Ans. is 'd' i.e., Buffered glycorol salineOrganismTransport mediaStreptococcus pyogenesPike's mediumNeisseriaStuart's medium, Amies mediumFor stool specimenBuffered glycerol saline, Carly-Blair, Stuart mediumSalmonella, ShigellaSach's buffered glycerol salineV choleraeVR medium, Cary-Blair medium, Autoclaved sea waterB...
Microbiology
Enterobecteriaceae
8ab66c14-d112-42ad-8e9c-9ee1207dba4e
All are true about SLE in pregnancy except?
Increased anti Ro and La implies low risk for congenital hea block
Steroids can be continued in pregnancy
Recurrent aboions
Disease may worsen during pregnancy
0a
multi
Increased anti Ro and La implies high risk of congenital hea block. Anti Ro antibody can be transmitted transplacentally and can lead to complete hea block leading to neonatal lupus. Steroids can be given in pregnancy as they fall in category A with no evidence of teratogenicity. But a placental enzyme 11 dehydrogenase...
Medicine
Systemic Lupus Erythematous
17b2a788-0342-4b41-b506-ae1957474ad2
An orbital tumor has the following characteristics: Retrobulbar location within the muscle cone, well defined capsule, presents with slowly progressive proptosis, easily resectable, occurs most commonly in the 2" to 4th decade. The diagnosis is:
Hemangiopericytoma
Dermoid
Capillary hemangioma
Cavernous hemangioma
3d
single
Cavernous hemangioma Cavernous hemangioma is the most common benign, intraconal tumor in adults. Hemangiopericytoma is also retro bulbar intraconal lesion. found in adults but is a rare tumor. Moreover owing to its tendency to invade the adjacent tissues, its margins are less distinct than cavernous hemangioma. Rest 2 ...
Ophthalmology
null
01b8f62c-b829-4619-8bca-15f8c32936df
Cillia can transport radiolabelled particle in antrum with:
1-20dm/min
20-30mm/sec
1-20mm/ min.
20-30mm/min
2c
single
Cilia can transport radiolabeled particles an average of 6mm/min, with a range of 1-20mm/min. Thus this transport can clear inhaled particles from nasal cavity in 10-20 min.
Surgery
null
47061482-b9e0-4fc4-8e9b-60eee08c7bf0
Following can lead to osteomalacia EXCEPT-
Vit D deficiency
Phosphorus deficiency in diet
Gastrectomy
Lack of exposure to sunlight
1b
multi
Calcium is the most abundant cation in the body and powerful homeostatic mechanisms control circulating ionised calcium levels . The WHO's dietary guidelines for calcium differ between countries, with higher intakes usually recommended in places with higher fracture prevalence. Between 20% and 30% of calcium in the die...
Medicine
Nutrition
f01994ac-f4b0-41f9-8e1d-a6d80ff064f7
All the following inflammatory mediators are derived from the cells except
Kinins
Cytokines
Histamine
Leukotriene
0a
multi
. Kinins
Pathology
null
49bd2bf5-0c06-4867-b960-eac795885840
Investigation of choice for subdural hemorrhage is?
Angiography
NCCT
CECT
MRI
1b
single
Ans. (b) NCCTRef Appendix-81 for "Traumatic intracranial hemotomas
Radiology
Brain Imaging: Anatomy, Trauma, and Tumors
5e859f3d-34ba-4bef-aee9-f1f6e4916c08
Hydatid disease of liver is caused by -
Strongyloides
Echinococcus granulosus
Taenia solium
Trichinella spiralis
1b
single
The larval stage is present in the animals including man,giving rise to hydatid cyst.Sheep ,pigs,cattle ,horse ,goat and man may act as intermediate host. Hydatid cyst involve liver , lung,brain,hea,kidney,spleen,bone,musclesetc. Liver is the commonest site and right lobe is frequently involved.The disease remains symp...
Microbiology
parasitology
44efcde8-dadc-4ad5-9072-142f27d84768
A 30-year-old man has had cramping abdominal pain and bloody diarrhea for the past 4 days. On physical examination, there is diffuse tenderness on palpation of the abdomen. Bowel sounds are present. There are no masses and no organomegaly. A stool culture is positive for Shigella flexneri. The episode resolves spontane...
Borrelia burgdorferi
Chlamydia trachomatis
Epstein-Barr virus
HLA-B27
3d
single
This patient developed enteritis-associated arthritis affecting the lumbar and sacroiliac joints several weeks after Shigella dysentery. He subsequently developed conjunctivitis and, most likely, uveitis. This symptom complex is a classic representation of a cluster of related disorders called seronegative spondyloarth...
Pathology
Osteology
a3f66cbc-7ab6-452f-89c9-6cd2f11a0289
Radiolucent periapical lesions have the following except
Absence of lamina dura
Hanging drop of oil effect
Opaque diffuse appearance
No movement on cone shift
2c
multi
The features of periapical inflammatory lesions vary depending on the time course of the lesion. More chronic lesions may show lytic (radiolucent) or sclerotic (radiopaque) changes, or both. The lamina dura around the apex of the tooth usually is lost.  In most instances, the periphery of periapical inflammatory lesion...
Radiology
null
277e5854-0aaf-4fe7-9c9d-aa5c0be13c48
Biological value of proteins refers to the
Proteins efficiency ratio
Proteins biologic value
Protein energy ratio
Calorific value
0a
single
null
Biochemistry
null
6e03305d-8eb7-4eed-ac9e-1e7185e28458
All are risk factors for preterm delivery except :
Absence of fetal fibronectin at < 37 weeks
Previous history of preterm baby
Asymptomatic cervical dilatation
Chylamydial infection of genital tract
0a
multi
Absence of fetal fibronectin at < 37 weeks
Gynaecology & Obstetrics
null
4494fbef-0f7e-4975-b9dd-2e62e906aed8
Antitumor activity is shown by all except -
Cytotoxic T lymphocytes
Natural killer cells
Basophils
Macrophages
2c
multi
Ananthanarayanan and Paniker's textbook of microbiology 9th edition. cytotoxic T cells can kill and lyse target cells carrying new or foreign antigens including tumor,allograft and virus infected cells. Natural killer cells are natural defence against virus infected and malignant mutant cells. activated macrophages sec...
Pathology
General pathology
5d9c1eff-11e3-4085-a87d-ff4cb6fd3c76
Immunoglobulins are produced by -
Macrophages
B-cells
T-cells
NK-cells
1b
single
Immunoglobulin (Ig),is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune systema Ref: Ananthanarayan & Panikers textbook of microbiology 9th edition pg:94
Microbiology
Immunology
44414268-895e-45c1-8ac2-d042a296ba11
Single most important feature to diagnose fetal aneuploidy:
Increased nuchal translucency
Absent nasal bone
Cystic hygroma
Abnormal ductus venosus flow
0a
single
Ans: (a) Increased nuchal translucencyRef: Current Progress in Obstetrics and Gynecology, John Stud, Volume Page 17Ultrasound markers of fetal aneuploidy:Nuchal translucency is the single most powerful tool. More than 3 mm needs evaluationAbsence of nasal boneAbsence or reversal of flow in the ductus venosus on Doppler...
Gynaecology & Obstetrics
Physiology & Histology
22f594da-aa3b-43ab-85e8-f0393fa9f0ba
Ponderal's index for "small for gestational age" child: March 2013
Less than 1
Less than 2
Less than 3
Less than 4
1b
multi
Ans. B i.e. Less than 2 Ponderal Index (for neonates) Calculated as Weight in gm X 100/ (length in cm)3 A child with ponderal index 3.0 or more can be considered overweight but in some conditions such as in maternal smoking, reduced length may also be implicated. An index between 2.5 and 3.0 is considered normal, Betwe...
Pediatrics
null
c9ed13b1-a79b-492b-8f80-2e4ea584b1f3
Earnest Klein has classified habits into
Compulsive and non-compulsive habits
Intentional and non-intentional habits
Primary and secondary habits
Pressure and non-pressure habits
1b
single
null
Dental
null
64aa1d06-2182-4d7c-95fa-1353145de45f
Suspended animation is seen with -a) Electrocutionb) Strangulation hangingc) Drowningd) Burn
a
bc
ad
ac
3d
single
null
Forensic Medicine
null
911974d3-9ff4-4b66-a4df-39f59bd8c7dc
According to European laryngeal Society, Subligamental cordectomy is classified as
Type I
Type II
Type III
Type IV
1b
single
Subligamental cordectomy is classified as Type II Excision of vocal cord after splitting the larynx (cordectomy laryngofissure) Ref: PL Dhingra; Textbook of EAR, NOSE and THROAT; edition 6; page no 310
ENT
Larynx
0746a56e-758f-4953-9b11-e620a1b44e31
Infeility can be defined as: UP 11; KCET 13
Not conceiving after 3 years of marriage
Not conceiving after 2 years of unprotected intercourse
Not conceiving after 1 year of unprotected intercourse
Not conceiving after 1 year of marriage
2c
single
Ans. Not conceiving after 1 year of unprotected intercourse
Forensic Medicine
null
e928c226-c5f8-4814-9e12-2c967322d0b5
The commonest cause of primary amenorrhea with ambiguous genitalia in a female with 46XX chromosome :
21 hydroxylase def.
17 hydroxylase def.
11 hydroxylase def.
Desmolase hydrolase def
0a
single
A i.e. 21- hydroxylase deficiencyClassic 21 - hydroxylase deficiency is most common cause of ambiguous genitalia in new born (virilization) and primary amenorrheaQ. i.e. Pseudohermaphroditism of female childPrimary amenorrhea with VirilizationQ in females is in:- 21 - hydroxylase deficiency- 11 - Hydroxylase deficiency...
Physiology
null
f8e7cc4c-5a67-4417-b57f-01e9658cde2c
While going for oxidation in the mitochondria, free fatty acid are transpoed by:
None of the above
Albumin
Globulins
Chylomicrons
1b
multi
Free fatty acids (FFA)-also called unesterified (UFA) or nonesterified (NEFA) fatty acids--are fatty acids that are in the unesterified state. In plasma, longer chain FFA are combined with albumin, and in the cell they are attached to a fatty acid binding protein. Shoer chain fatty acids are more water-soluble and exis...
Biochemistry
null
4172a596-6779-4263-94e9-d940ecd9894a
Sepsis of index finger will spread to?
Thenar
Mid-palmar
Hypothenar
All of the above
0a
multi
Ans. a (Thenar).Deep thenar space infection occurs in the potential space between the palmar aponeurosis and the fascia overlying adductor policis, which contains not only the flexor pollicis longus tendon plus the neurovascular (NV) bundles to the thumb, but also the NV bundle on the radial side of the index plus the ...
Anatomy
Upper Extremity
46079119-0e05-478d-98af-aa59a83800d1
Spherocytosis of RBC is a common feature in -
G6PD deficiency
Sickle cell anemia
CML
All
0a
multi
null
Pathology
null
267e7535-dabf-4ff2-9ebf-04da0201aedf
Defective chromosome associated with De-George syndrome is -
7
15
17
22
3d
single
Ans. is 'd' i.e., 22 This syndrome encompasses a spectrum of disorders that result from a small deletion of band q 11.2 on long arm of chromosome 22. Clinical features are considered to represent two different disorders :-1) Di George syndromeThese patients have thymic hypoplasia with resultant T-cell immunodeficiency....
Pathology
null
b875cad7-bec7-49ca-9cc2-76451f3f6717
all are true about s1 except
lower frequency than s2
caused by closure of mitral valve
heard at the end of ventricular systole
better heard with diaphragm of stethescope
2c
multi
CHARACTERISTICS OF S1 Normally heard as fused single hea sound Medium to High Frequency Low Pitched Best heard with diaphragm M1 louder than T1 M1 best heard at apex T1 best heard at Left LSB Splitting can be heard in Expiration and L-LSB ref : harrisons 21st ed
Medicine
All India exam
fcde14ea-557e-4cb0-b76b-612c6bd8a847
Central dot sign is seen in
Primary sclerosing cholangitis
Liver Hamaoma
Caroli's disease
Polycystic liver disease
2c
single
"central dot" sign: enhancing dots within the dilated intrahepatic bile ducts, representing poal radicles (seen in CT).
Surgery
G.I.T
17f6cd36-ed6a-4e7c-9ff7-d895c4d0e074
Which of the following is/are an example(s) of non-Mendelian inheritance?
Genomic imprinting
Uniparental disomy
Mitochondrial inheritance
All of the above
3d
multi
Single-Gene Disorders with Non classic Inheritance. -This group of disorders can be classified into four categories: Diseases caused by trinucleotide-repeat mutations Disorders caused by mutations in mitochondrial genes Disorders associated with genomic imprinting Disorders associated with gonadal mosaicism
Pathology
Introduction
0ed1c33b-10bc-4d5a-860d-b6dfdca6f68f
The period of training for a village health guide is -
1 month
3 months
6 months
12 months
1b
single
After selection village health guide undergoes a sho training in primary health care.The training is arranged in nearby health center,subcenter or any other suitable place for the duration of 200 hours ,spread over a period of 3 months.During training period they receive a stipend of Rs 200 per month (refer pgno:902 pa...
Social & Preventive Medicine
Health care of community & international health
07144811-37a0-4e2f-9ec5-140606e88a64
Which of the following minerals does not act as prosthetic group in enzymes?
Copper
Cobalt
Selenium
Manganese
3d
single
null
Biochemistry
null
bb4074ae-1c8d-4a32-b221-873eaba4900b
A 50 year old man presents with paresthesia. Hb = 6.8 gms/dl. Peripheral smear shows macrocytes and neutrophis with hypersegmented nuclei. Endoscopy reveals atroghic gastritis. Which of the following deficiency is more likely?
Fotate deficiency
Vitamin B12 deficiency
Riboliavan deficiency
Fotate deficiency
1b
single
above clinical features point towards Vit B12 deficiency due to Pernicious anemia. Pernicious anemia -Type II Hypersensitivityin which ABs are formedagainst intrinsic factorthus inhibits the binding of IF+B12. Intrinsic factor deficiency-Malabsorption of vitamin B12 - Megaloblastic anemia /Pernicious anemia
Physiology
NEET Jan 2020
9f1e7890-c902-4f64-8379-bc27b4a6640b
Which of the following is a stage of intuitive thought appearance in jean-Piaget scheme :
Senosorimotor
Concrete
Preoperational stage
Formal operations stage
2c
single
C i.e. Preoperational stage
Psychiatry
null
8ff22222-2a6e-4429-8515-21a8be8b7229
Normal IOP is range is ____________
10 - 15 mmHg
5 - 10 mmHg
11 - 21 mmHg
9 - 25 mmHg
2c
single
null
Ophthalmology
null
dca93437-dd28-4ec2-9299-4b9810a8a3fd
An expectant mother feels quickening at :
12-14 weeks
16-20 weeks
26 weeks
24-28 weeks
1b
single
In second trimester the pregnant women feels much better ,the nausea vomiting and bladder frequency is almost gone She slowly stas feeling growing uterus per abdomen Of interest and excitement to her is the very first perception of foetal movement called quickening felt at around 18 weeks in a primigravida and 16 -18 w...
Gynaecology & Obstetrics
General obstetrics
84b07a64-cca5-4cb2-b879-691b6241f202
Renal transplantation, in which mother acts as a donor of one kidney to her son is an example of
Autograft
Heterograft
Allograft
Xenograft
2c
multi
Ans. is 'c' i.e., Allograft Transplantation terminologyAutograft:Tissue transplanted from one part of the body to another in the same individual.Also called an autotransplant.Isograft:Is a graft of tissue between two individuals who are genetically identical (i.e. monozygotic twins). Transplant rejection between two su...
Surgery
Transplantation
16946f6b-bae0-4dbd-a61d-66b4cfb8def6
Giving commission to other doctor is -
Dichotomy
Covering
Professional secrecy
Professional neglect
0a
single
null
Forensic Medicine
null
d5f32579-6df8-40b2-9104-ff5d902fde58
All of the following statements about Zenker's diveiculum are true Except:
Acquired diveiculum
Lateral X-rays on Barium swallow are often diagnostic
False Diveiculum
Out pouching of the anterior pharyngeal wall, just above the cricopharyngeus muscle
3d
multi
Ans is D i.e. Out pouching of the anterior pharyngeal wall, just above the cricopharyngeus muscle Zenker's diveiculum is out pouching of the posterior pharyngeal wall, where pharyngeal mucosa herniates through the Killian's dehiscence (the weak area between the upper oblique fibres and the lower horizontal fibres of th...
Surgery
null
6628225e-5e29-49af-b179-01b06a3d9fcf
The administration of succinylcholine to a paraplegic patient led to appearance of dysarrythmias, conduction abnormalities and finally cardiac arrest. The most likely cause is :
Hypercalcemia
Hyperkalemia
Anaphylaxis
Hypermagnesemia
1b
multi
null
Pharmacology
null
60a3c729-6898-4d1f-a086-dcf6a998bc38
The blood pressure measured by a sphygmomanometer
Is lower than the intraaerial pressure
Is higher than the intraaerial pressure
Is same as the intraaerial pressure
Is the same with different cuff sizes
1b
single
At the point at which systolic pressure in the aery just exceeds the cuff pressure, a spu of blood passes through with each heabeat and, synchronously with each beat, a tapping sound is heard below the cuff.Ref: Ganong&;s Review of Medical Physiology 25th Edition. Page: 577
Physiology
Cardiovascular system
77ec9a20-6182-4caf-9b12-a79941858aca
A decrease in basal metabolic rate (BMR) is seen in which of the conditions?
Obesity
Hypehyroidism
Feeding
Exercise
0a
single
Obesity by definition is an increase in the amount of adipose tissue mass or fat mass. Adipose tissue is relatively ine from a metabolic rate. Basal metabolic rate depends on the amount of metabolically active tissue or the lean body mass. An obese individual has higher propoion of fat relative to lean body mass than a...
Physiology
null
86371fc4-0956-4adc-a97c-234f1495b167
Patient with fixed dilated pupil, with iris atrophy and secondary glaucoma after penetrating keratoplasty is suggestive of.
Benedict's syndrome
Posner-Shlossman syndrome
Kaufmann's syndrome
Urrets Zavalia syndrome
3d
single
Ans. d. Urrets Zavalia syndrome A fixed dilated pupil following penetrating keratoplasty is a well recognized if rare postoperative complication. The mydriasis following penetrating keratoplasty was first described by Castroviejo but it was Urrets-Zavalia who first published his observations on a series of six cases an...
Ophthalmology
null
2e08902d-7b6f-4bd8-ab0a-179b5e5b18f3
Which of the following is not used for emergency contraception?
Mifepristone
IUCD
Levonorgestrel
Danazol
3d
single
Emergency contraception should be given within 72 hours of unprotected sex. They interfere with postovulatory events which normally results in pregnancy and therefore known as incentives - As the most common method and drug is - levonorgestrel with success rate of 95 %.the tablets can be offered up to 120 hours. howeve...
Gynaecology & Obstetrics
JIPMER 2018
d3e89be7-ac10-4b96-8d9f-0d526c52ccf8
About first order kinetics,true statement is
Clearance remains constant
Fixed amount of drug is eliminated
Half life increases with dose
Decreases clearance with increased dose
0a
multi
Clearance is variable in zero-order kinetics because a constant amount of the drug is eliminated per unit time, but it is constant in first-order kinetics, because the amount of drug eliminated per unit time changes with the concentration of drug in the blood Ref-KDT 6/e p32
Anatomy
General anatomy
19148abf-9095-4144-a1b1-fc185870b621
True statement about streptococcus faecalis ?
Growns in 6.5% Nacl solution
Are lactose fermenter
Easily destroyed at 60 C for 30 minutes
Classified on the basis of teichoic acid of cell wall
0a
multi
Ans. is 'a' i.e., Growns in 6.5% Nacl solution
Microbiology
null
db9f752e-09b8-4311-ba28-987b7206593f
In national vector borne disease control program which disease is not included?
Malaria
Yellow fever
Japanese encephalitis
Kala azar
1b
single
Ans. (b) Yellow feverRef. K. Park 21sted./380* The National Vector Borne Disease Control Programme (NVBDCP) is implemented for the prevention and control of vector borne diseases such as: Malaria, Filariasis, kala-azar, Japanese encephalitis, Dengue and Chikunguniya.* Yellow fever is NOT a part of NVBDCP.
Social & Preventive Medicine
Health Programmes in India
9d5a3303-7e9b-40b1-b60e-c662ab6ea553
Last pa of the hea to be repolarised is:
Apical epicardium
Apical endocardium
Epicardium of the base of LV
Endocardium of the base of LV
1b
single
Depolarization occurs from apex to base & endocardium to epicardium; Repolarization occurs from base to apex & epicardium to endocardium Last to depolarize are: Base of LV (epicardium) Pulmonary conus. Upper most pa of interventricular septum. Last to repolarise: Apex endocardium
Physiology
Conducting System of Hea
68780356-f951-4925-ae8e-68f0315520b7
Hassal's corpuscles are seen in:
Thymus
Spleen
Bone marrow
Lymph node
0a
single
Hasal's corpuscles/thymic corpuscles are structures found in the medulla of the human thymus, formed from type VI epithelial reticular cells.They are named for Ahur Hill Hassall, who discovered them in 1849.
Anatomy
null
e5c89f0e-a5b1-4f61-b46c-f382adfd8be4
At the altitude of 6500 meters, the atmospheric pressure is 347 mmHg. What is the inspired PO2.
73 mm Hg
63 mm Hg
53 mm Hg
83 mm Hg
1b
single
According to law of paial pressures : Pressure exeed by a gas in a mixture is directly propoional to its concentration in the mixture. In inspired gases; 20 % = O2 78% = N2 PH2O = 47 mmHg (air humidified with inspiration) =347 - 47 = 300 mmHg = gaseous component
Physiology
Respiratory System Pa 2
22eedb2a-b0c4-4120-8468-97a33b17d9ba
Management of medulloblastoma in 1.5 year old. What is not done in curative therapy?
Open surgery with leaving the tumour margins
Chemotherapy
Total cranial spinal irradination
VP shunt for the obstructive hydrocephalus
0a
single
. Treatment consist of relief of raised intracranial pressure,establishment of pathological diagnosis,removal of beningn tumors,decompressive surgeries for malignant tumor,shunt surgeries to drain CSF_ventriculo peritonial shunt or ventriculo atrial shunt,radiotherapy ,chemotherapy-temozolamide (Ref;SRB's Manual of Sur...
Surgery
Trauma
b2de0197-0e1b-44dc-9253-e388fb9ca386
Sandfly can fly upto –
50 yards
100 yards
200 yards
300 yard
0a
single
null
Social & Preventive Medicine
null
9e3599f3-7dbf-428f-8992-a948c3afe5f8
A middle aged female repoed with dull diffuse progressive headache of 2 months duration associated with episodes of vomiting and blurred vision at times. Cough increases the headache.Likely patient has
Vascular headache
Intracranial space occupying lesion
Intracerebral hemorrhage
Acute pyogenic meningitis
1b
single
A space-occupying lesion of the brain is usually due to malignancy but it can be caused by other pathology such as an abscess or a haematoma. Almost half of intracerebral tumours are primary but the rest have originated outside the CNS and are metastases Features of a headache indicating a high risk of a space-occupyin...
Medicine
C.N.S
2fca93ab-33f1-4502-9bda-3bd7721040d2
Porcelain jacket crowns are contraindicated in
Hypoplastic teeth
Excessive horizontal overlap
Decay is extensive but pulp is vital
Excessive vertical overlap with little horizontal overlap
3d
single
null
Dental
null
c7ca2e8c-b647-4426-b965-e095dda2593b
Which is not secreted by stomach?
Lipase
Pepsinogens
HCI
None
3d
multi
Gastric lipase is an acidic lipase secreted by the gastric chief cells in the fundic mucosa in the stomach. It is a weak fat-splitting enzyme. Pepsinogen is secreted by the chief cells of main gastric glands which are found in the body & fundus of stomach. It is a proteolytic enzyme. HCl is secreted by the parietal cel...
Physiology
G.I.T
8adad11f-e7f2-409a-a7d3-8bcdd08d3cf8
Which of the following is an alternative to methadone for maintenance treatment of opiate dependence
Diazepam
Chlordiazepoxide
Buprenorphine
Dextropropoxyphene
2c
single
The withdrawal symptoms can be managed by one of the following methods: 1. Use of substitution drugs such as methadone 2. Clonidine is a a2 agonist that acts by inhibiting norepinephrine release at presynaptic a2 receptors. 3. Naltrexone with Clonidine: Naltrexone is an orally available narcotic antagonist which, when ...
Psychiatry
Substance abuse
59d21cbf-5c87-4bf8-aeb7-1c8389af7f22
The MOST likely site of lesion in a patient with Wernicke's hemianopic pupil is:
Optic nerve
Optic tract
Optic chiasma
Optic radiation
1b
single
Wernicke's hemianopic pupil indicates lesion in the optic tract. In this condition light reflex is absent when light is thrown on temporal half of the retina of the affected side and nasal half of retina of the opposite side. In this condition light reflex is present when light is thrown on nasal half of affected side ...
Ophthalmology
null
7d5c1319-4421-4cb6-b1c6-2437bb30cfe4
Use of oral contraceptives increases the risk of which cancer -
Colon
Ovary
Breast
All of the above
2c
multi
Ans. is 'c' i.e., breast * Important adverse effects of OCPs are: (1) Nausea, vomiting, headache (worsening of migraine), (2) breakthrough bleeding, (3) mastalgia, (4) weight gain, (5) acne and hirsutism, (6) cholasma and pruritis, (7) carbohydrate intolerance, (8) leg vein and pulmonary thrombosis, (9) coronary and ce...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
620f465e-eb5b-4bdd-98b2-228c42b36d39
Most common location of accessory spleen
Hilum of spleen
Greater omentum
Lesser omentum
Duodenum
0a
single
Accessory spleen, in other words supernumerary spleens, splenunculi, or splenules, results from the failure of fusion of the primordial splenic buds in the dorsal mesogastrium during the fifth week of fetal life. Incidence of accessory spleen in the population is 10%-30% of patients in autopsy series and 16% of patient...
Anatomy
Abdomen and pelvis
667a3f95-ea64-4d3f-994f-e85af726b178
Leaving (or forgetting) an instrument or sponge in the abdomen of the patient during a surgery and closing operation is:
Contributory negligence
Civil
Corporate negligence
Criminal negligence
3d
single
Ans. d (Criminal negligence). (Ref. Textbook of FMT by Parikh 6th ed. 1.46)Contributory negligencea common law defence to a claim or action. It applies to a situation where a plaintiff claimant has, through their own negligence, caused or contributed to the injury they suffered. For example where a pedestrian crosses a...
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
6d8c69ec-7c80-457e-9722-15cb45322bcd
In a pregnant female, there is decreased requirement of the spinal anaesthetic agent because of all of the following except –
Exaggerated lumbar lordosis
Decreased volume of subarachnoid space
Engorgement of epidural veins
Increased sensitivity of the nerves to anaesthetic agent
0a
multi
A smaller dose of local anaesthetic is nedded to produce the same level of neuraxial block in pregnant women compared with nonpregnant women. The causes may be :- Compression of the inferior vena cava by the pregnant uterus causes "distension or engorgment" of the epidural venous plexus. This decreases the volume of ...
Anaesthesia
null
bebe375a-e3f2-4c9f-b3b3-38e49fd9fe15
True statement regarding upper GI bleeds:
It is bleeding up to ampulla of Vater
Most common cause is variceal bleeding
Rockall-Baylor scoring is used for risk stratification
Most common management is endoscopic banding
2c
multi
UPPER GI BLEED: Bleeding up to Lig. of Treitz M/c cause- Non-variceal peptic ulcer bleeding Causes of upper gastrointestinal bleeding Condition % Ulcers 60 Oesophageal 6 Gastric 21 Duodenal 33 Erosions 26 Oesophageal 13 Gastric 9 Duodenal 4 Mallory-Weiss tear 4 Oesophageal varices 4 Tumour 0.5 Vascular lesions, e.g. Di...
Surgery
NEET 2018
af6ede0f-b05c-4ba0-b6eb-95d65726e98d
All of the following are seen in Lichen planus except?
Max - Joseph spaces
Civatte or colloid bodies
Koebner's phenomenon
Absent granular cell layer
3d
multi
Granular cell layer is absent in psoriasis where as Lichen planus is characterized by Hypergranulosis. Necrotic / apoptotic keratinocytes are called as "colloid / civatte bodies" and spaces left at the dermo - epidermal junction are termed as "Max - joseph spaces".Both are seen due to autoimmune destruction of basal ke...
Dental
null
793e4313-c80d-4104-8536-1934ec41d980
In human body the action of surfactant is done by
Sugar and salt
Soap and water
Lipid and protein
Base and lipid
2c
single
null
Physiology
null
30ba1a9e-a923-48aa-95aa-84b1097e78d0
Noonan syndrome is characterized by all except
Hypertrophic cardiomyopathy
Dysplastic pulmonary stenosis
Pectus excavatum
Coarctation of aorta
3d
multi
Coarctation  of aorta  is not the cardiovascular manifestation  in Noonan syndrome.
Medicine
null
abe79175-df99-4942-98bc-9a5532ee3f70
Pain Assessment Tool is best done by
Ask patient
Tachycardia
Tachypnea
Bradypnea
1b
single
(B) TachycardiaPAT - Pain Assessment ToolParameters012Posture/tone ExtendedDigits widespreadShoulders raised off bedFlexed and/or tenseFists clenchedTrunk guardingLimbs drawn to midlineHead and shoulder resist posturingCryNo YesWhen disturbedDoesn't settle after handlingLoudWhimperingWhiningSleep patternRelaxed Agirate...
Anaesthesia
Miscellaneous
b8b0fbea-955f-4225-805f-107004159f51
Most fatal amoebic encephalitis is caused by ?
E.histolytica
Naeglaria
E. dispar
Acanthamoeba
1b
single
Ans. is 'b' i.e., Naeglaria . Amongst the given options Naeglaria and Acanthamoeba cause amoebic encephalitis. " The prognosis of Naeglaria encephalitis is uniformaly poor, most patients die within a week."---Harrison "Acanthamoeba encephalitis follows a more indolent course."----- Harrison . So, amongst the given opti...
Microbiology
null
40e55353-bcf0-4135-a12b-3957f16ea6a4
In an adult, the hyoid bone is seen at which of the following level of the cervical veebrae?
C2
C3
C4
C5
1b
single
The hyoid bone is found at the level of third cervical veebrae in adults. It is situated above the thyroid cailage in the anterior wall of the hypopharynx in relation to the base of the tongue. It is made up of a body, bilateral greater cornua and bilateral lesser cornua. It is a sesamoid bone and is suspended in betwe...
Unknown
null
142ba68c-1dbf-4702-b166-8d9cf1996f8b
Which of the following statements about Von-Hippel Lindau syndrome is true
Multiple tumors are rarely seen
craniospinal hemangioblastomas are common
Superatentorial lesions are common
Tumors of Schwann cells are common
1b
multi
Harrison's principles of internal medicine 17th edition. *In VHL somatic mutation of normal allele leads to retinal angiomas, CNS hemangioblastoma,pheochromocytomas and multicentric clear cysts,hemangiomas and adenomas of kidney
Medicine
C.N.S
96582c88-5b6f-48ee-80f3-5cde74c3b8c4
Which of the following statement regarding measurement of BP with sphygmomanometer versus intra aerial pressure measurements is true?
It is less than intravascular pressure
It is more than intravascular pressure
It is equal to intravascular pressure
It depends upon blood flow
1b
multi
The measurement of aerial pressure using a sphygmomanometer bag with a standard arm cuff is subject to inaccuracy leading to falsely high aerial pressure readings. Using sphygmomanometer blood flow is detected. The accuracy of blood pressure measurement is affected by the cuff size. Inadequate cuff size result in false...
Physiology
null
4966014a-b26a-4c39-b8b6-9bfdbb638e4c
The earliest sign of iron deficiency anaemia -
Increase in iron binding capacity
Decrease in serum ferritin level
Deorease in serum iron level
All the above
1b
multi
<p>Plasma ferritin is a measure of iron stores in tissues & is the single test to confirm iron deficiency .It is a very specific test. In the course of development of anaemia, firstly storage iron(ferritin) depletion occurs during which iron reserves are lost without compromise of the iron supply for erythropoiesis.</p...
Medicine
Haematology
48c5a2e3-2e0c-4a3f-a28f-b90edd413c82
Most potent bronchodilator among inhalational anesthetic agents is
Isoflurane
Sevoflurane
Halothane
Desflurane
2c
single
Effect of inhalational agents on respiratory systemAll inhalational agents are bronchodilators -Halothane cause maximum bronchodilatation. The inhalational agent of choice in asthmatics (intravenous anaesthtic of choice is ketamine).All inhalational agents cause respiratory depression to some extent - Maximum depressio...
Anaesthesia
All India exam
f14357e0-9c08-4f21-89bb-53ab50f5658b
Compared to the other antidepressant drugs miazapin has the distinct ability to act as an antagonist of:
Beta receptors
D2 receptors
Alpha 2 receptors
5-HT receptors
2c
single
Ref: KDT 8th ed Miazapine blocks presynaptic [?]2 receptors on NA and 5-HT neurons. This increases the release of both NA and 5-HT. It also inhibits 5-HT2 and 5-HT3 receptors.
Pharmacology
Central Nervous system
eb70eca5-1408-4c2c-b14a-3028575e87ca
Primary sites of lymphocyte production are
Bone marrow and Thymus
Spleen and Lymph nodes
Lymph nodes and mucosa associated lymphoid tissue
Spleen and mucosa associated lymphoid tissue
0a
single
null
Physiology
null
820584ed-441b-4e8b-86fe-b0e26f0bad97
All is true about von Hippel Lindau syndrome except:
Hemangioblastomas seen in craniospinal axis
Multiple tumors common
Tumors of Schwann cells are common
Supratentorial lesions are uncommon
2c
multi
C i.e. Tumors of Schwann cells are common Von Hippel-Lindau (VHL) syndrome is associated with multiple hemangioblastomasQ of infratentorial craniospinal axis, retina and pancreas. Supratentorial HB are uncommonQ.
Radiology
null
4ff4e373-1da7-46d1-a04c-afcdd4a781a2
Nucleus ambiguus is composed of:
7,9,10 cranial nerve nucleus
7,9,11 cranial nerve nucleus
9,10,11 cranial nerve nucleus
7,10,11 cranial nerve nucleus
2c
single
Ans. C. 9,10,11 cranial nerve nucleusCells in nucleus ambiguus contain motor neurons associated with three cranial nerves (rostral pole = C.N. IX = glossopharyngeal; middle part = C.N. X = vagus; caudal pole = C.N. XI = spino accessory). Axons arising from nucleus ambiguus pass laterally and slightly ventrally to exit ...
Anatomy
Neuroanatomy
0aa7db35-7ac5-420a-80ed-3917a903e922
At what age a child's height is expected to be 100 cm?
2 years
3 years
4 years
5 years
2c
single
ANSWER: (C) 4 yearsREF: Essence of Paediatrics Prof. MR Khan 4th ed page 59, Clinical Pediatrics by D. N. Chatterjee page 18 A simple rough formula for calculation height from 2-14 years is:Height in inches = (2.5 x age in years) + 30* Thus the expected height at 4 year of age = (2.5 x 4) + 30 = 40 inches* As 1 inch = ...
Pediatrics
Assessment of Growth
7c72df63-be30-451d-ac7c-8c5d8b20f1b6
True about mesenteric vein thrombosis ?
Peritoneal signs are always present
Invariably involves long length of bowel
I.V. Heparin is the treatment of choice
Surgery can lead to sho-bowel syndrome
3d
multi
Answer is 'd' i.e. Surgery can lead to sho-bowel syndrome Peritoneal signs are present in less than half the cases. Any length of bowel may be involved depending on the level and extent of thrombosis. Resection of the nonble bowel along with its mesentry is the treatment of choice. Heparin is given in all cases and alo...
Surgery
null
93bee656-c09b-4907-89d5-b6adc81a2aa0
Dysphagia caused by in Plummer Vinson Syndrome is due to
Stenosis
Web
Stricture
Ulceration
1b
single
(Web) (1024-25-LB) (737, 1043-B &L 25th)Plummer-Vinson Syndrome (Brown-Kelly Paterson syndrome or sideropenic dysphagia)* Young women with iron deficiency anaemia and dysphagia referred high in the neck.* The dysphagia was said to be caused by spasm or a web in the post-cricoid area. The patients were said to have an i...
Surgery
Oesophagus
6eab2227-b112-43d2-9912-853a65e2985b
Most common cause of ectopic ACTH production-
Renal cell carcinoma
Hepatocellular carcinoma
Small cell carcinoma lung
Pheochromacytoma
2c
multi
Ans. is 'c' i.e.. Small cell carcinoma lungo Ectopic ACTHproduction accounts for 10-20% cases of cushings syndromeo Small cell lung carcinoma (SCLC) is by far the most common causes of ectopic ACTH.# If accounts for more than 50%cases of cushings syndrome due to ectopic ACTH production.Other carcinomas associatedThymic...
Medicine
Adrenal