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135
b0c1e7c9-b9e8-474b-8606-0b4c0f4c7034
Binswanger&;s disease is a form of
Hypeensive retinopathy
Hypeensive nephropathy
Hypeensive encephalopathy
Subcoical leukoencephalopathy
3d
single
Binswanger's disease, also known as subcoical leukoencephalopathy and subcoical aeriosclerotic encephalopathy (SAE), is a form of small vessel vascular dementia caused by damage to the white brain matter. White matter atrophy can be caused by many circumstances including chronic hypeension as well as old age.
Pathology
Nervous system
f4b317cd-a4fe-49d0-acc3-1922fcfd789f
Crippling fluorosis occurs at what level ?
0.5-0.8 mg/litre
1.5 mg/litre
3-6 mg/litre
> 10 mg/litre
3d
single
Ans. is 'd' i.e., 10 mg/liter Crippling fluorosis This occurs at fluoride level > 10 mg/litre (PPM). Patient is crippled and bed ridden.
Social & Preventive Medicine
null
827f4fab-9803-4075-8f03-3784ea8a031b
Lineage specific T Cell marker is
CD 1
CD 19
CD 3
CD 4
2c
single
CD 3 is considered as lineage specific for Tcells.
Pathology
null
c1953066-fd7d-4d3a-98c6-4efc0293e812
Oesophageal manometry is used in:
Cancer esophagus
Barrett esophagus
Schatzki ring
Achalasia cardia
3d
single
Ans. (d) Achalasia CardiaRef Bailey and Love 26th edition Page 1015* Manometry is the investigation to study the physiology of the functions of esophagus.* It is the investigation of choice to detect the motility disorders like achalasia cardia, DES, nut cracker esophagus.* Barrett IOC: Endoscopic biopsy* Cancer Esopha...
Surgery
Oesophagus
f236e8e3-3ca8-491a-82d2-2411cb9d22c9
Syndrome associated with anosmia is:
Goldenhar syndrome
Kallmann syndrome
Prader Willi syndrome
All of the above
1b
multi
The most well-known type of congenital anosmia is Kallmann syndrome, an X-linked disorder. Caused by mutation in the KAL gene, Kallmann syndrome is characterized by hypogonadotropic hypogonadism, which results when olfactory receptor neurons and neurons synthesizing gonadotropin-releasing hormone fail to migrate from t...
ENT
null
6c316e83-e64c-4c9d-bcaf-6b08de309883
Anesthetic agent contraindicated in acute intermittent porphyria is?
Halothane
Isoflurane
Propofol
Thiopentone
3d
single
Ans. is 'd' i.e., Thiopentone Anesthetics in porphyriaSafeUnsafe (should not be used)* Propofol* Benzodiazepines* Opioids (other than pentazocine)- morphine, codeine, pethidine, fentanyl, alfentanyl, naloxone* Lidocaine, Bupivacaine* Muscle relaxants* Neostagmine, atropine, glycopyrrolate* Aspirin, indomethacin, naprox...
Anaesthesia
Complications Of Anaesthesia
78c06cb6-cd01-4d62-bb80-f587835d3298
Anterior scalloping of veabrae seen in -
Obsteogenesis imperfecta
Aoic aneurysm
Metastasis
Renal Cell Ca
1b
multi
Ans is option 2... Aoic aneurysm Anterior scalloping is seen in following conditions Aoic aneurysm, tuberculous spondylosis, lymphadenopathy, delayed motor development (in downs syndrome) Posterior scalloping is seen in Tumors in spinal canal (ependymoma, lipoma,, neurofibroma), neurofibromatosis, acromegally, achondro...
Medicine
Endocrinology
c8aa1b3f-76dd-4c07-99b0-5067677413bd
Reversible dementia is seen in all EXCEPT:
Wernickes encephalopathy
Alzheimer's
Hypothyroidism
Head trauma
1b
multi
Ans. (b) Alzheimer'sRef: Harrison's 18th ed. 3300-07* Alzheimer's disease is most common cause of irreversible dementia.Reversible vs Irreversible dementiaReversibleIrreversibleVitamin deficiency# B1-Wernicke's# B12-SCID# Nicotinic acid- PellagraAlzheimer'sEndocrine (hypothyroidism, adrenal insufficiency, cushing's)Vas...
Psychiatry
Dementia Due to Metabolic Causes
35f0dcd8-6720-4eb5-9f01-a3959028e0a4
Which sign is seen due to thrombosis of mastoid emissary veins?
Battle sign
Gresinger sign
Irwin Moore Sign
Hennebe's sign
1b
single
Ans. is'b'i.e., Gresinger sign (Ref Dhingra 5th/e p. 95) Griesinger's sign: - Edema over the posterior pa of mastoid due to thrombosis of mastoid emissary veins.
ENT
null
52bd2eec-f439-4db3-80d5-de2eaeb844da
What is incidence of emergence delirium after ketamine anaesthesia-
5% to 30 %
30 % to 55 %
55 % to 70 %
100%
0a
single
The observed incidence of emergence delirium after ketamine ranges from 5% to 30 %.
Anaesthesia
Intravenous Anesthetic Agents
01dcc307-a222-4eb0-87b3-34dc9992b44b
This drug has activity against many strains of P. aeruginosa. However, when it is used alone, resistance has emerged during the course of treatment. The drug should not be used in penicillin-allergic patients. Its activity against gram-negative rods is enhanced if it is given in combination with tazobactam. Which of th...
Amoxicillin
Aztreonam
Piperacillin
Vancomycin
2c
multi
Antipseudomonal penicillins: Piperacillin and Ticarcillin are called antipseudomonal penicillins because of their activity against Pseudomonas aeruginosa. Piperacillin and Ticarcillin are effective against many gram-negative bacilli But not against Klebsiella because of its constitutive penicillinase. Formulation of ti...
Pharmacology
Cell Wall Synthesis Inhibitors
1aab304f-c04f-42c9-9db4-66ac2d1f26f4
TESPAL done in -
Severe epistaxis
Rhinophyma
CA Maxillary Sinus
Multiple Antrochoanal polyps
0a
single
Ans. is'a' i.e., Severe epistaxisManagement of intractable spontaneous epistaxis.TESPAL - transnasal endoscopic sphenopalatine aery ligationIndication:Epistaxis not responding to conventional conservative management.Posterior epistaxis
ENT
null
502cc028-3dc8-4aef-8aa0-7b08a05b0cd4
The mean of the 25 patients' plasma volumes is 12.5 litres. Standard detion is 0.25. Calculate standard error
0.05
0.5
0.01
0.1
0a
single
S.E = S/[?]n S = Standard detion = 0.25 n = sample size = 25 S.E. = 0.25/[?] 25 = 0.25/5 = 0.05
Social & Preventive Medicine
Biostats
f94a5d87-676f-4f09-bd41-5113fb2ee0bc
Best gas used for creating pneumoperitonium at laparoscopy is :
N2
2
CO2
N20 Goniometer is used
2c
single
CO2 CO, is the gas used to create pneumoperitoneum during laparoscopy. Other option is - N20 : But it is expensive, less soluble in blood and suppos combustion. Also know : Instrument used for creating pneumoperitoneum is veress needle. Flow Rate of CO, for creating pneumoperitoneum 200 - 2000 ml/min & pressure between...
Gynaecology & Obstetrics
null
9eae3cf5-29f0-4797-8a08-038964dd1081
Which of the following drug is contraindicated in a patient of myasthenia gravis: September 2008
Succinylcholine
Tubocurare
Pyridostigmine
Halothane
1b
single
Ans. B: Tubocurare Drugs contra-indicated in myasthenia gravis Absolute contraindication: - Curare - D-penicillamine Botulinum toxin - Interferon alpha Contraindicated -- Antibiotics -- aminoglycosides (gentamycin, kanamycin, neomycin, streptomycin, tobramycine); macrolides (erythromycin, azithromycin, telithromycin,) ...
Pharmacology
null
37208d8d-02b8-4334-94b2-235d4f88bc5f
Which of the following can be blocked by atropine, a muscarinic receptor blocker?
Increased blood pressure caused by nicotine
Increased skeletal muscle strength caused by neostigmine, an acetycholine esterase inhibitor
Bradycardia caused by infusion of acetylcholine
All of these
2c
multi
Atropine is a muscarinic antagonist. Muscarinic antagonists competitively inhibit the effect of acetylcholine at muscarinic receptors. Bradycardia caused by infusion of acetylcholine- can be blocked by atropine
Pharmacology
Parasympathetic System & Glaucoma
b9d83937-dd54-42e0-a25c-c405163558ba
In an apexification procedure, any excess calcium hydroxide periapically:
Will cause necrosis in the Periapical tissues
Will resorb on its own
Will be removed by multinucleated giant cells
Will have to be removed by apicoectomy
2c
multi
null
Dental
null
380fe628-43c3-42d9-8c15-3f03afd88f11
Specific cell surface proteins, such as alkaline phosphatase, and lipoprotein lipase, are anchored to the cell membrane. This anchoring is accomplished by covalent binding through an oligosaccharide bridge to component of the cell membrane. This component is
Sphingomyelin
Phospphatidic acid
Phosphatidylserine
Phosphatidylinositol
3d
single
Phosphatidylinositol derivatives play several distinct roles in the cell membrane, one of which is that they anchor several cell surface proteins. Cell surface pro­teins bound to phosphatidylinositol are also found in several parasitic protozoa. By altering these proteins, these protozoa can change their antigenic prop...
Unknown
null
9bd2a5ee-4bbe-4368-a0f1-5cc00a7316c0
The most common cause of Left Ventricular Hyperophy is:
Hypeension
Aoic Stenosis
Aoic Regurgitation
HOCM
0a
single
Answer is A (Hypeension) The most common cause of Left Ventricular Hyperophy is Systemic Hypeension Left Ventricular Hyperophy may be produced as a result of all of the above conditions but systemic hypeension remains the single most common cause. Left Ventricular Hyperophy (LVH) Pressure overload states: Hypeension (m...
Medicine
null
fccda7f8-40c0-483d-bc3d-b48dd904da13
Lung to lung metastasis is seen in-
Adenocarcinoma of lung
Squamous cell carcinoma
Small cell carcinoma
Neuroendocrine tumor of lung
0a
multi
Ref:Textbook of pathology (Harsh mohan) 6th edition,page no.500 Adenocarcinoma, also called peripheral carcinoma due to its location and scar carcinoma due to its association with areas of chronic scarring, is the most common bronchogenic carcinoma in women and isslow-growing.Recent estimates on adenocarcinoma place th...
Pathology
Respiratory system
3160fdd5-97a6-46dc-8fe2-9ed718d98779
Regarding the lipid or liposomal formulation of amphotericin B which of the following statements is accurate
They are expensive to use than conventional amphotericin B
There are more effective in fungal infections than conventional preparations because they increase tissue uptake of amphotericin B
They may decrease the niprotoxicity of amphotericin B
They have wider spectrum of antifungal activity than conventional formulation of amphotericin B
2c
multi
Ref-KDT 6/e p758 Newer liposomal preparations of amphotericin B have the following features: Less chances of nephrotoxicity and infusion related reactions Lesser uptake in the tissues like kidney More expensive Similar in efficacy and antifungal spectrum as conventional preparations
Anatomy
Other topics and Adverse effects
b39eba8d-30c0-4f3f-87e7-eaacf146e416
Which of the following is IL-2 receptor inhibitor :
Basiliximab
Daclizumab
Both 1 & 2
None of the above
2c
multi
Both Basiliximab & Daclizumab are monoclonal antibodies against IL-2 receptor.
Pharmacology
null
dfd015cf-b529-4b53-a6c6-ebb0038c8de0
Which vaccine is recommended in disasters -
Typhoid
Cholera
BCG
Diphtheria
3d
single
Ans. is 'd' i.e., DiphtheriaVaccines recommended in disasters -* Following vaccines are recommended1) Children < 10years:- DPT, inactivated polio (IPV), H.influenzae type b (Hib), hepatitis B, pneumococcal conjugate vaccine (PCV), measles-mumps-rubella (MMR), varicella vaccine, influenza, hepatitis A and rotavirus.2) C...
Social & Preventive Medicine
Hospital waste, disaster management and occupational health
dd614810-d6b1-42e1-a3f5-4cff4ddc9a4e
Glomus cells are found in
Bladder
Brain
Chemoreceptors
Kidney
2c
single
The glomus cells (type I) are specialized glandular-like cells, mainly located in the carotid bodies and aoic bodies, that control the respiratory activity.The glomus cells have a high metabolic rate and good blood perfusion and synapses directly or indirectly with nerve endings. Thus are sensitive to changes in aerial...
Anatomy
Brain
cb9bdee7-69d8-4448-84aa-aa9c965029a7
Which of the following is not produced by hepatocytes:September 2006, September 2012
Gamma globulin
Albumin
Fibrinogen
Prothrombin
0a
single
Ans. A: Gamma globulinThe hepatocyte manufactures serum albumin, fibrinogen, and the prothrombin group of clotting factors (except for Factor 3,4)It is the main site for the synthesis of lipoproteins, ceruloplasmin, transferrin, complement, and glycoproteinsThe liver forms fatty acids from carbohydrates and synthesizes...
Physiology
null
24793afc-a307-4364-8a4e-8ef966d72a6b
Potential complications stemming from dentigerous cyst are
Ameloblastoma
Epidermoid carcinoma
Mucoepidermoid carcinoma
All of the above
3d
multi
null
Pathology
null
420a2722-22db-43ed-8bb0-a801ee21815d
The commonest presentation of meckel's diveiculum is -
Bleeding
Obstruction
Diveiculitis
Intussception
0a
single
Ans. is 'a' i.e., Bleeding
Surgery
null
ffa635c4-cfb0-46c8-861c-e87f12e0ab22
Which of the following immunoglobulin is absent in Ataxia telangiectasia:
IgG
IgM
IgA
IgD
2c
single
Ataxia telangiectasia (AT) Present in the first decade of life with progressive telangiectatic lesions associated with deficits in cerebellar function and nystagmus. There is a high incidence of recurrent pulmonary infections (bronchiectasisQ) and neoplasms of the lymphatic and reticuloendothelial system. It is caused ...
Pathology
Immunodeficiency Disorders
79dfabe0-c5e4-4bdd-ab5c-eafc226e059d
A patient complaining of difficulty of swallowing of solid foods is suffering from all of the following except:
diffuse esophagus spasm
Achalasia cardia
esophageal carcinoma
bulbar palsy
3d
multi
null
Medicine
null
c89d9525-543e-4b32-a230-592a6b6a8ccc
An adult with newly diagnosed tuberculosis is most likely to have which of the following types of lesions?
A single lesion in a lung apex
A single lesion in the gastrointestinal tract
A single lesion subjacent to the pleura
Both a lesion subjacent to the pleura in the lower pa of an upper lobe and active disease in the mediastinal lymph nodes
0a
multi
This is something of a trick question, but it stresses an impoant fact many medical students do not realize. Primary tuberculosis infection characteristically involves the lung subjacent to the pleura in either the lower pa of the upper lobe or the upper pa of a lower lobe of one lung. The mediastinal nodes are also us...
Medicine
null
f2d1b59e-78ae-4249-95c5-0ae6d6631fd2
Essential for tumour metastasis is ?
Angiogenesis
Tumorogenesis
Apoptosis
Inhibition of tyrosine kinase activity
0a
single
Angiogenesis Tumour angiogenesis plays a very significant role in the metastasis since the new vessel formed as a pa of growing tumour are more vulnerable to invasion because these evolving cells are in direct contact with cancer cells. According to Harrison "Cancer research studying the conditions necessary for cancer...
Pathology
null
7e17f476-dc9b-4225-8fec-32ea1546f763
Todd's palsy can occur after episode of
Generalised tonic clonic seizures
Paial motor seizures
Atonic seizures
Myoclonic seizures
1b
single
Todd's paralysis, or Todd's palsy. Specialty. Neurology. Todd's paresis (or postictal paresis/paralysis, "after seizure") is focal weakness in a pa or all of the body after a seizure. This weakness typically affects appendages and is localized to either the left or right side of the body. Ref Harrison20th edition pg 24...
Medicine
C.N.S
d26ccee5-d063-4250-a917-6b9613940bdc
Pheochromocytoma may be associated with:
Medullary carcinoma of the thyroid
Papillary carcinoma of the thyroid
Anaplastic carcinoma of the thyroid
Follicular carcinoma of the thyroid
0a
single
Ans. A. Medullary carcinoma of the thyroidMEN 2a: Sipple syndromeMEN 2ba. Thyroid; Medullary thyroid carcinomaa. Thyroid: Medullary thyroid carcinomab. Pheochromocytomab. Pheochromocytomac. Parathyroid hyperplasiac. Mucosal neuromas and Marfanoid appearance
Medicine
Endocrinology
04eaa6a3-57eb-440c-b646-52014381a87b
A patient with alkaline urine which is cloudy with plenty of pus cells is suffering from:
E. coli
Proteus
TB
None
1b
multi
Ans: b (Proteus)Ref: Bailey & Love, 24th ed, p. 1324 & 23rd ed, p. 1191Proteus and Staphylococcus split urea, forming ammonia which makes the urine alkaline and promotes formation of calculi.
Surgery
Urinary Tract
acefb136-1def-48e8-82fb-5995abbf6e0d
In a population of 10,000, literate people are 4000. In same population 2000 are 0-6 years old. What is the literacy rate of that population -
30%
40%
50%
60%
2c
single
Ans. is 'c' i.e., 50% * The term literacy rate is used for the population relating to seven years age & above.* In the given question, population 7 years 8c above is 8000. Out of which 4000 are literate thus literacy rate is 50%.
Social & Preventive Medicine
Demography and Family Planning
5d554deb-c524-44e6-aeb7-aad93d03e5d7
Which of the following is not true about apoptosis?
Presence of inflammation
Bleb formation
Eosinophillia
Cell shrinkage
0a
multi
Ans. is 'a' i.e., Presence of inflammation o The two most striking features of apoptosis are:i) In contrast to necrosis it does not elicit inflammationii) Considerable apoptosis may occur in tissues before it becomes apparent in histological section (because it occurs very rapidly).Morophological changes in apoptosisi)...
Pathology
Apoptosis
61569796-c7f7-4681-a4d7-e8657633db3b
All of the following are causes of acalculous cholecystitis except
Bile duct stricture
Schitosoma
Prolonged TPN
Major operations
1b
multi
Causes of Acalculous cholecystitis Common causes Elderly and critically ill patients after trauma Burns Longterm TPN Major operations(Abdominal aneurysm repair and cardiopulmonary bypass) Diabetes mellitus Uncommon causes Vasculitis Obstructing GB adenocarcinoma GB torsion Parasitic infestation Unusual bacterial infect...
Anatomy
G.I.T
bb53176e-4b9d-48d8-9e06-01b37e7e6a7b
Biotin deficiency is due to
Avidin
Flavoproteins
Metallo flavoproteins
Oxireductase
0a
multi
(Avidine) (146 - U.S 3rd) (178- R.S. 7th)Biotin deficiency (anti egg, white injury factor, vitamin B7 or vitamin - H) is a sulfur containing B complex. It is directly participates as coenzyme in the carboxylation reactions* High consumption of raw egg. The raw egg white contains a glycoprotein - avidin. Which is highly...
Biochemistry
Vitamins and Minerals
58e94502-1590-4e40-a976-f2fa2a28dfe0
Which one of the following virus is double stranded RNA virus?
Hepatitis -A
Hepatitis-E
Reo virus
Corona virus
2c
single
All RNA viruses are single stranded except Reo virus.
Microbiology
null
2de3bca4-56b6-4ff2-ac27-bd830e80d147
Urine sample examinations is a useful investigation in infestation of
S. haematobium
S. japonicum
S. mansoni
E.vermicularis
0a
single
Ans. a (S. hematobium) (Ref. H - 18th/ ch. 219)SCHISTOSOMIASIS (BILHARZIA)Distribution and important species of Schistosoma are:# S. japonica is found in Central and Eastern China, and the Philippines and nearby islands; and primarily affects the liver and intestines.# 5. mansoni is found in Africa, the Eastern Mediter...
Microbiology
Parasitology
ec1f1814-923b-4ba0-933c-7050718eb16d
Genus neisseria is -
Gram positive diplococci
Gram negative diplococci
Gram negative coccobacilli
Gram positive bacilli
1b
single
Ans. is 'b' i.e., Gram negative diplococci o The genus Neisseria consists of Gram negative aerobic nonsporulating, non motile oxidase positive cocci typically arranged in pairs (diplococci).o Two important pathogens are -N. meningitidisN. gonorrhoeae
Microbiology
Bacteria
37d0ba6d-d4c0-47e3-9a6f-5d0596aba822
L-Dopa is combined with carbidopa in the treatment of parkinsonism to -
Decrease the efficacy of levodopa
Decrease the efficacy of levodopa
Increase the dose of levodopa required
Inhibit conversion of levodopa to dopamine in the CNS
1b
single
Ans. is 'b' i.e., Inhibit peripheral decarboxylation of levodopa Carbidopa is combined with levodopa to inhibit peripheral decarboxylation of levodopa and make more levodopa available to cross the blood brain barrier to reach its site of action.
Pharmacology
null
7a37eba3-6c88-44af-b8d2-37f7b9727d5b
Acrodermatitis entropathica is
AD
AR
X-linked recessive
None
1b
multi
Acrodermatitis enteropathica is an autosomal recessive disorder postulated to occur as a result of mutations in the SLC39A4 gene located on band 8q24.3. The SLC39A4 gene encodes a transmembrane protein that is pa of the zinc/iron-regulated transpoer-like protein (ZIP) family required for zinc uptake. This protein is hi...
Pathology
miscellaneous
82f732a0-3cf3-49f6-8e94-ca4ce3a5060d
Which of the following is used in beta–blocker overdose ?
Atropine
Glucagon
Calcium chloride
All of these
3d
multi
null
Pharmacology
null
9b7cceee-02f8-47b4-9a8c-e716704b7e7f
Commonest cause of hea failure in infancy is ________
Myocarditis
Rheumatic fever
Cardiomyopathy
Congenital hea disease
3d
single
Most common cause of congestive cardiac failure in infants is congenital hea disease. Ref : Ghai essential of pediatrics, eighth edition ,p.no:397
Pediatrics
C.V.S
124f34d5-a898-4fc4-9d88-2ca022a6277a
Which of the following tests are used in the evaluation of a suspected CSF leak?
Beta 2 microglobulin
Beta 2 transferrin
Tyroglobulin
Transthyretin
1b
single
Detection of beta-2 transferrin is considered pa of standard evaluation when CSF leak is suspected. Nasal and ear fluids are tested for detection of the beta-2 transferrin band by immunofixation electrophoresis (IFE) or Western blot analysis as a diagnostic tool for the presence of CSF or perilymph. This test is helpfu...
Unknown
null
4b2de5ed-2a66-4c75-81bc-f6dcaec06ff3
Which of the following decreases in length during the contraction of a skeletal muscle fiber?
A band of the sarcomere
I band of the sarcomere
Thick filaments
Thin filaments
1b
single
The physical lengths of the actin and myosin filaments do not change during contraction. Therefore, the A band, which is composed of myosin filaments, does not change either. The distance between Z disks decreases, but the Z disks themselves do not change. Only the I band decreases in length as the muscle contracts.
Physiology
Muscle
ee6b7553-1433-41fb-ac93-9500b356da1b
Criteria for diagnosing SIRS all seen except:
Temp > 38.5 degC or < 36 degC
RR > SD above normal for age
Children <1 year old persistent bradycardia over 0.5 hour
>50% immature neutrophils
3d
multi
D i.e. >50% immature neutrophilsRef: Nelson, Textbook of Pediatrics, 20th edition, page 522Explanation:Systemic Inflammatory Response Syndrome (SIRS)It's an inflammatory cascade that is initiated by the host in response to infection, occurs when the host defense system does not adequately recognize or clear the infecti...
Pediatrics
Infection
b99a2f4c-758b-4a99-addb-0ba246a0ded3
According to myogenic theory of renal autoregulation, the afferent aerioles contract in response to stretch induced by
NO
Noradrenalin
Opening of Ca2+ channels
Adenosine release
2c
single
Myogenic autoregulation - through opening of Calcium channels Tubuloglomerular feedback - through release of adenosine Ref: Ganong 25th ed/page 678
Physiology
Renal physiology
84048e94-d814-442a-808a-879d0445a416
Maxillary aery is
Branch of facial aery
Branch of internal carotid aery
Branch of common carotid
Terminal branch of external carotid
3d
single
Branches of external carotid aery Anterior Superior thyroid Lingual Facial Posterior Occipital Posterior auricular Medial Ascending pharyngeal Terminal Maxillary Superficial temporal Ref BDC volume 3 ;sixth edition pg 101
Anatomy
Head and neck
a4a470f4-92ee-43f9-b957-b278e4819808
Amsler sign?
Fuch heterochromatic iridocyclitis
Posner-schlossman syndrome
Uveal-effusion syndrome
None of the above
0a
multi
Ans. is `a' i.e., Fuch heterochromatic iridocyclitis During paracentesis in Fuch's heterochromic iridocyclitis, there is bleeding from neo-vasculorization.This is known as "Amsler's sign". Fuch's heterochromic iridocyclitis (Fush's uveitis syndrome) It is a form of anterior and intermediate uveitis. The condition is us...
Ophthalmology
null
b8d45715-98f8-4758-985c-22d2cd87b2ff
Cruel behavior towards wife by husband, family members or his relatives comes under which IPC section:
498 A
304
304 A
304 B
0a
single
Ans. (a) 498 ARef.: The Essentials ofFSM by K.S. Narayan Reddy 31st ed. / 272-73* Cruel behavior towards wife by husband or his relatives punished by IPC 498 A.* IPC section 498 A states that whosoever being husband or relative subject women to cruelty shall be punished with imprisonment of upto 3 years with or without...
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
5130b7ab-cc6c-4a5c-b826-7ee0d80744cf
All are true about scrub typhus, except :
Causative organism is O. Tsutsugamoshi
Vector is trombiculide mite
Adult female feeds on vertebrate hosts
Tetracycline is the drug of choice
2c
multi
“Mite feeds on serum of warm blood animals only during there larval stage (chiggers) and adult mites feed only on plants” Scrub typhus : Caused by O. tsutsugamushi Transmitted by trombiculid mite which also shows transovarian spread Clinical features : Fever, headache, myalgia, cough and GI symptoms. Classic case inclu...
Unknown
null
19f834b3-c27f-4da2-8e65-974917b544eb
Which of the following amino acid is active at neutral pH?
Histidine
Glycine
Leucine
Arginine
0a
single
Ans. aRef.: Harper's Illustrated Biochemistry, 30th edn.Option aTrueYes, due to its pyrolidone ring is stable at neutral pH (pH 7)Option bFalseNo, glycine is simplest amino acid and not affected by pHOption cFalseNo, it is steric hinderance is there due to branched chain amino acidOption dFalseNo, false, it is not affe...
Biochemistry
Proteins and Amino Acids
6794d3d4-0930-46be-a02e-ee2019ec02b8
Which of the following is a content of bicipital groove?
Synol membrane of shoulder joint
Ascending branch of anterior circumflex aery
Ascending branch of posterior circumflex aery
Radial aery
1b
single
Bicipital groove of inteubercular sulcus of humerus: The groove lies between greater and lesser tuberosities of humerus. Bilaminar tendon of the pectoralis major is inseed into the lateral lip of the groove. Teres major is inseed into the medial lip of the groove. Tendon of the latissimus dorsi is inseed into the floor...
Anatomy
null
1d1ddb70-4684-43e5-8110-86c17582bd64
Which of the following statements is true regarding the pituitary gland -a) It is separated from the optic chiasma by the sella turcicab) It is situated deep in the sellac) The sphenoidal air cells lie inferior to itd) It develops from the base of the 3rd ventricle form the pars anteriore) It is supplied by a branch of...
ab
bc
bce
ace
2c
multi
Pituitary is situated into sella turcica. Optic chiasma is superior to pituitary. Sphenoidal air sinuses are inferior to pituitary. Pituitary is supplied by a single inferior hypophyseal artery and several superior hypophyseal arteries. These hypophyseal arteries are branches of internal carotid artery. Evagination of ...
Anatomy
null
b290a296-464b-4665-b8e6-2484d5e8f29b
All of the following are Glycoproteinoses, EXCEPT
Fucosidosis
Sanfilippo A syndrome
Sialidosis
a-mannosidosis
1b
multi
Ans: b) Sanfilippo A syndrome Sanfilippo A syndrome is a mucopolysaccharidosis, not Glycoproteinoses. Lysosomal hydrolases like a-neuraminidase, b-galactosidase, b-hexosaminidase are involved in the degradation of oligosaccharide chains during glycoprotein turnover. Enzyme defects lead to abnormal degradation of glycop...
Biochemistry
Classification of carbohydrate
7617db68-4875-4f8f-9198-ab4ae1dfd24e
What is the total osmolarity of low osmolarity ORS?
311 mmol/ litre
300 mmol/ litre
245 mmol/ litre
250 mmol/ litre
2c
single
Composition of reduced osmolarity ORS: Components Amount in mmol/ litre Sodium 75 Chloride 65 Glucose, anhydrous 75 Potassium 20 Citrate 10 Total osmolarity 245 Ref: Park 21st edition, page 202.
Social & Preventive Medicine
null
baacd431-3ccb-4c63-a2a6-c869c5bc24cd
Chronic hemodialysis in ESRD patient is done
Once per week
Twice per week
Thrice per week
Daily
2c
single
Ans. (c) Thrice per weekRef : Harrison 19th ed. /1823For the majority of patients with ESRD, between 9 and 12 h of dialysis are required each week, usually divided into three equal sessions.Current Targets of Hemodialysis* Urea reduction ratio (the fractional reduction in blood urea nitrogen per hemodialysis session) o...
Medicine
Dialysis
c2fbef77-7777-4d5e-9f25-7ad17ba420ad
The action of styloglossus muscle is
Protrusion of tongue
Posteriorly retracts the tongue
Depression of tongue
Elevation of tongue
1b
single
null
Anatomy
null
7c385c10-36aa-4854-bbc2-621b8d6b4fe8
Sideroblastic anemia is caused by all except -
Collegen vascular disease
Iron deficit
Lead poisoning
Cutaneous porphyria
1b
multi
This is a refractory anaemia defined by the presence of many pathological ring sideroblasts in the bone marrow.These are abnormal erythroblasts containing numerous iron granules arranged in a ring or collar around the nucleus.Sideroblastic anaemia is diagnosed when 15% or more of marrow erythroblasts are ring siderobla...
Pathology
Haematology
5647f3de-c7dc-45f7-a700-208933d88e65
Which one of the following form Blood Brain Barrier?
Astrocytes and endothelial cells
Choroidal cells
Oligodendrocytes
Endothelial cells exclusively
0a
single
(A) Astrocytes and endothelial cells # "Blood Brain Barrier" (BBB) results from the selectivity of the tight junctions between endothelial cells in CNS vessels that restricts the passage of solutes.> At the interface between blood and the brain, endothelial cells are stitched together by these tight junctions, which ar...
Anatomy
Misc.
c91d0278-1949-4230-b570-4d265e8ea127
Primary prevention includes all, except:
Marriage counselling
Health education
Self breast examination
Health promotion
2c
multi
Pap smear and self breast examination are screening methods Ref: Park, 20th Edition, Page 39
Social & Preventive Medicine
null
b8db32f6-e533-47c1-b07c-5e57b5fcb3c8
Subdural empyema is a complication of all the following conditions except?
Frontal Sinusitis
Skull vault osteomyelitis
Middle ear disease
Boil over face
3d
multi
d. Boil over face(Ref: Nelson's 20/e p 2936-2948, Ghai 8/e p 563-565)Infections of the sinuses, ear and skull bones can lead to Subdural empyema.
Pediatrics
Central Nervous System
3afea785-3cae-40c0-b566-52f38010c446
The complication of diabetes which cannot be prevented by strict control of blood sugar is -
Amyotrophy
Nerve conductivity
Macular edema
Microalbuminuria
2c
single
Ans. is 'c' i.e., Macular edema o The DCCT demonstrated that improvement of glvcemia controly Reduced nonproliferative and proliferative retinopathy (47% reduction).y Microalbuminuria (39% reduction).y Clinical nephropathy (54% reduction).y Neuropathy (60% reduction).y Improved glycemic control also slowed the progress...
Medicine
Diabites & Inappropriate Antidiuretic Hormone
57b250f6-2c04-4fcb-91aa-240cc61a6c54
In cancer colon investigation of choice is:
CT scan
Barium enema
Colonoscopy
X-ray
2c
single
Ans. (c) ColonoscopyRef: Bailey and Love 27th edition, Page 1262* Investigation of choice for cancer colon is colonoscopy as we can take biopsy and confirm the lesion.* Risk of perforation is 1:1000.* Helps to detect synchronous lesions also.
Surgery
Small & Large Intestine
e6c0b5f8-8aa7-40f4-b936-b9f6317cc568
Which is the only amino acid with good buffering capacity at physiological pH?
Arginine
Glutamic acid
Histidine
Valine
2c
single
Histidine plays a key role in making hemoglobin an excellent buffer in red blood cells.
Biochemistry
null
62eb368d-0730-4a2d-8b5c-09cef7f6f144
Normal expiratory reserve volume of adult?
500 ml
3000 ml
1200 ml
4500 ml
2c
single
Ans. is 'c' i.e., 1200 ml(Ref: Ganong 24n/e p.629)Inspiratory reserve volume - 3000 mlExpiratory reserve voulume -1200 ml
Physiology
null
33af0d9a-8aff-45d9-9ab3-7ebeb9049643
Fixation at which psychosexual stage results in development of OCD-
Oral
Anal
Phallic
Genital
1b
multi
Phase Age Organ of Gratification Psychiatric disorders linked to fixation 1 Oral Phase Bih to 1 1/2 years Oral region 2 Phases: Oral erotic phase (sucking) Oral sadistic phase (biting) Schizophrenia Dependent personality disorder Alcohol dependence syndrome 2 Anal Phase 1 1/2 to 3 years Anal and perianal area 2 Phases:...
Psychiatry
Sexual Disorders
928adc66-24a4-4d07-9887-5c36a9761e2d
Recurrent laryngeal nerve is in close association with:
Superior thyroid artery
Inferior thyroid artery
Middle thyroid vein
Superior thyroid vein
1b
single
Ans. is 'b' i.e. Inferior thyroid arteryRef: B.D. C 2nd/e Vol III page 137 & 138, Repeat Inferior thyroid artery is a branch of the thyrocervical trunk. During its course it passes behind the carotid sheath and the middle cervical sympathetic ganglion and its terminal part is related to the recurrent laryngeal nerve.Mo...
Surgery
Surgical Approaches to the Thyroid
72d8b08e-8aad-4f5f-aad7-4e9479ad3da0
All the following are characteristic feature of Cluster headache except:
Periodic pain
Conjunctival injection
Bilateral photophobia
No response to oral sumatriptan
2c
multi
Ans: C (Bilateral photophobia) Ref: Hcirrisotis principles of Internal Medicine. 18th edition. 2012. Chapter 14. Pg.112Explanation:CLUSTER HEADACHEThe pain is deep, usually retroorbital, excruciating in intensity, nonfluctuating, and explosive in quality.A core feature of cluster headache is Periodicity. At least one o...
Medicine
Headache
f8bf5f96-9ca3-44f0-bdbb-e4bc5a8cc7e1
Drugs which cause hirsutism are all except
Methyldopa
Penicillamine
Phenothiazines
Metoclopramide
1b
multi
Penicillamine causes Hypertrichosis, not Hirsutism.
Gynaecology & Obstetrics
null
4a0449e1-1402-422e-b289-3aa0d50fa9c8
In a child, the anaesthetic of choice is –
Enflurane
Isoflurane
Sevoflurane
Halothane
2c
single
null
Anaesthesia
null
9ee1e565-88d3-402e-a1a0-adc7abbab653
Delayed tuberculin test response is due to: September 2004
B lymphocytes
T lymphocytes
Monocytes
Histiocytes
1b
single
Ans. B i.e. T lymphocytes
Microbiology
null
638da813-7930-423d-8edf-5d99478f4aff
A 70-year-old man with a history of diabetes presents with severe pain in his right ear. The patient was diagnosed with external otitis. Further tests suggested that the patient suffered bone and nerve damage. Clinical laboratory analysis showed that the isolated microorganism produced a distinct blue pigment as well a...
Staphylococcus epidermidis
Staphylococcus aureus
Pseudomonas aeruginosa
Enterococcus faecalis
2c
single
External otitis or swimmer's ear is an inflammation of the outer ear and the ear canal. In the virulent form of the disease-malignant external otitis, which occurs in people with diabetes, damage to the cranial nerves and bone may occur. External otitis is caused by either bacterial or fungal pathogens. Bacterial patho...
Microbiology
Bacteria
56795eac-0c42-446e-b4e8-34972d7bc325
Mallory weiss syndrome common in
Chronic alcoholic patients
Smokers
Occupational benzene therapy
Bladder carcinoma
0a
multi
(Chronic alcoholic patients) (236, 1746-H) (242, 1854-H17th)Mallorv-Weiss Syndrome - classic history is vomiting, retching or coughing preceding hematemesis, especially in an alcoholic patients.* Bleeding usually on the gastric side of the gastroesophageal junction, Stops spontaneously in 80-90% of the patients and rec...
Medicine
G.I.T.
6cec4865-7fe6-4aea-97e5-45be384e41d0
Propaganda is defined as -
Forcing of knowledge into mind
Active aquiring of knowledge
Requiring knowledge after thinking
Training people to use judgement before thinking
0a
single
- propaganda is one in which knowledge is instilled in the minds of people. - prevents or discourage thinking by ready made slogans. - knowledge is spoon fed and passively received. Reference : Park's textbook of preventive and social medicine, 23rd edition, pg no:859 <\p>
Social & Preventive Medicine
Health education & planning
6feeda40-db11-4dbc-8b23-5ee83daf72e0
Which of the following ganglion is associated with lacrimation?
Otic
Ciliary
Sphenopalatine
Gasserian
2c
single
Secretomotor fibres for lacrimal gland arise from the facial nerve at geniculate ganglion, travel in greater petrosal nerve and join the sphenopalatine ganglion as vidian nerve. After relay in the ganglion, they are distributed to lacrimal gland.
ENT
Nose and PNS
34bbd81c-429e-4cef-a144-d98190bc587b
Best way to evaluate discrepancy in articular disc of TMJ is:
Transpharyngeal projection
MRI
Arthrography
Arthroplasty
1b
single
Soft tissues of the joint (articular disk) can be imagined with MRI or Arthrography. MRI produces superb images of the soft tissues in internal derangement of the disk. Arthrography is invasive and has the risk of infection and allergic reaction due to the contrast agent.
Radiology
null
9e93c585-dd94-408c-9d6c-aadca9b3c029
A 40-year-old male comes with complaint of indigestion and decreased appetite. He has a history of being treated for duodenal ulcer 4 years back. Investigation reveals elevation of gastrin levels. Which of the following statement is true regarding gastrin?
Secreted by parietal cells of stomach
Secreted by alpha ceils of pancreas
Decreases bicarbonate content in pancreatic secretion
It gets stimulated by endoluminal peptides in stomach
3d
multi
Ans: D (It gets stimulated by endolumina I peptides in stomach) Ref: Ganong's Review of Medical Physiology. 21st ed and Khurana Textbook of Medical Physiology By Khurana, pg: 605Explanation:GASTRINGastrin is secreted into the blood circulation and NOT into gastric juice.It reaches stomach through the arterial circulati...
Physiology
G.I.T.
529f2819-f6a0-45f7-abf2-309a19a8f9ed
Newer Influenza vaccine-
Split - virus vaccine
Conjugate vaccine
Live attennuated vaccine
Killed vaccine
0a
single
<p> Newer vaccines for influenza are Split virus vaccine Neuraminidase specific vaccine Recombinant vaccine. Park&;s textbook of preventive and social medicine,K.Park,23rd edition,page no:155. <\p>
Social & Preventive Medicine
Communicable diseases
256afddf-a243-4722-8b17-5674a19be31a
Treatment of choice for chloroquine resistant malaria is :
Mefloquine
Sulfadoxine + Pyrimethamine
Primaquine + Chloroquine
Chloroquine + Pyrimethamine
1b
single
Ans. is 'b'. Sulfadoxine + Pyrimethamine * Under the recent 'National anti-Malaria Programme.' the drug policy for malaria treatment is as follows-Any fever in endemic areas during transmission season without any other obvious cause may be considered as malaria and investigated/treated accordingly.Drug resistance foci ...
Social & Preventive Medicine
Communicable Diseases
a77a0f56-af91-43d1-9722-c176738153f9
Which of the following hypnotic drugs facilitates the inhibitory actions of GABA but lacks anticonvulsant or muscle relaxing properties and has minimal effect on sleep architecture
Buspirone
Diazepam
Phenobarbital
Zaleplon
3d
single
Zolpidem, zaleplon and zopiclone are agonists at BZD receptors. These are hypnotic drugs that lack muscle relaxant and anticonvulsant actions. These have negligible effect on REM sleep and do not affect sleep architecture.
Pharmacology
null
d3649dbf-ef2f-411a-9f23-d353faace3c7
All of the following statement regarding ewings sarcoma are true except?
Common location is diaphysis of long bones
Symptoms resemble osteomyelitic
Translocation +(11,22) is classical
Flexner-Wintersteiner rosettes.
3d
multi
In ewings sarcoma, Homer-Wright pseudo rosettes are seen. Flexner-Wintersteiner rosettes are seen in retinoblastoma.
Pathology
null
dcec74e5-ffd7-49e2-b935-45d850b235d6
Which of the following condition is not true about Hemochromatosis?
Hypogonadism
Ahropathy
Diabetes mellitus
Desferrioxamine is treatment of choice
3d
multi
Phlebotomy is the treatment of choice of hemochromatosis. Chelating agent desferrioxamine is indicated when anemia or hypoproteinemia is severe enough to preclude phlebotomy. Hemochromatosis is a common inherited disorder of iron metabolism in which dysregulation of intestinal iron absorption results in deposition of e...
Medicine
null
135981b2-be47-49c2-8698-f1d7395b63b2
Blood component products are all except?
Whole blood
Platelets
Lymphoma
None
3d
multi
Ans. is None
Surgery
null
814f414f-d71b-4616-b1cb-b21720b9d4aa
Which of the following is the best denture patient
skeptical
philosophical
critical
indifferent
1b
single
null
Dental
null
91845030-e2e8-46bb-b3ab-74d0d08b7a20
A patient requires tooth extractions from an area that has been subjected to radiation therapy. Which of the following represents the greatest danger to this patient:
Alveolar osteitis
Osteoradionecrosis
Prolonged healing
Fracture of the mandible
1b
single
null
Radiology
null
9c564b05-c791-4a2a-b607-28d70fa4e146
Which of the following drugs require therapeutic drug monitoring?
Metformin
Propranolol
Warfarin
Phenytoin
3d
single
* Therapeutic drug monitoring is adjustment of dose of the drug according to its plasma concentration. It is required for A Aminoglycosides (e.g. gentamicin) Drug Digitalis Possessing Phenytoin (anti-epileptics) Low Lithium Therapeutic Tricyclic antidepressants Index Immunomodulators (e.g. cyclosporine)
Pharmacology
Pharmacodynamics
8dd635e1-a437-46d5-a873-8fbcbe2477d8
Black line in the gingiva that follows the contour of the margin is due to:
Bismuth
Arsenic
Mercury
All of the above
3d
multi
Black line in the gingiva that follow the contour of the margin is due to Bismuth, Arsenic and Mercury.
Pathology
null
360af71e-fd3a-448e-b730-5de14c2292f9
Which of the following Immunoglobulin acts as a receptor for antigens
IgG
IgM
IgD
IgE
2c
single
Major Functions of ImmunoglobulinsImmunoglobulinMajor FunctionsIgGMain antibody in the secondary response. Opsonizes bacteria, making them easier to phagocytose. Fixes complement, whichenhances bacterial killing. Neutralizes bacterial toxins and viruses. Crosses the placenta.IgASecretory IgA prevents attachment of bact...
Biochemistry
miscellaneous
2daaa20b-6965-4fd2-adb3-121155ad7f76
By which nerve is the hip joint supplied ?
Deep peroneal
Femoral
Sciatic
Posterior cutaneous nerve of thigh
1b
single
Nerve supply of hip joint -        Femoral nerve- by nerve to rectus femoris -        Obturator nerve- by anterior division -        Nerve to quadratus femoris -        Superior gluteal nerve
Anatomy
null
0d05b3bc-2f44-456a-a622-41401c11606f
Which of the following statements is FALSE regarding vincristine?
It is an alkaloid
Its use is associated with neurotoxicity
It does not cause alopecia
It is a useful drug for induction of remission in acute lymphoblastic leukemia
2c
multi
Ans. (C) It does not cause alopecia(Ref: KDT 8th/e p924)Vincristine is a vinca alkaloid.It is used for the induction of remission in ALL.It is a marrow sparing drug but causes peripheral neuropathy, alopecia and SIADH as adverse effects.
Pharmacology
Chemotherapy: General Principles
85f61add-d2c1-4ea1-9787-e880cb058ff3
Maturation failure in poor absorption of the vitamin B12 causes:
Microcytic hypochromic
Sickle cell anemia
Occurs in 3-4 months after the absorption
Causes polycythaemia
2c
single
(Occurs in 3-4 months after absorption): Ref: 682-R (438- Basic pathology 8th)Vitamin B12 deficiency* Macrocytic megalablastic anaemia is the cardinal features* Usually pernicious (Addisonian) anaemiaDiagnostic features include:1. A moderate to severe megaloblastic anaemia2. Leukopenia with hypersegmented granulocytes3...
Pathology
Blood
d2b33719-b16b-4e2b-8311-19e2a680db7a
Rivastigmine is given in:
Depression
Alzheimer's disease
Schizophrenia
OCD
1b
single
(Ref: Katzung, 10th ed. Ch 7)* Rivastigmine is a parasympathomimetic drug used for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease* DOC for Alzheimer's disorder-Donepezil* DOC for OCD: Fluoxetine* DOC for parkinsonism: Levodpa + Carbidopa* DOC for drug induced ...
Pharmacology
C.N.S
2c3174e4-043e-476e-9ca8-17aab104377c
IOC for neonatal hypertrophic pyloric stenosis:
X Ray
CT scan
MRI
Ultrasound
3d
single
Ans. (d) UltrasoundRef: SRB Manual of Surgery 4th ed. 1877* Ultrasound abdomen is the investigation of choice for diagnosing hypertrophic pyloric stenosis.* It is reliable, highly sensitive, highly specific, and easily performed.* The mandatory measurements include pyloric muscle thickness and pyloric channel length.* ...
Radiology
Abdominal Radiography
e01fb990-5bab-41db-a0f3-2059a70a9522
Drugs causing hypokalemia are : a) Amphotericin B b) Insulin c) Cyclosporine d) Carbenoxolone e) NSAIDs
ace
ac
abd
acd
2c
single
null
Pharmacology
null
fb7347a0-1f01-462e-965d-5d8cb34eafed
A 42 yearold female has palpable purpura with rash over buttocks, pain in abdomen, and ahropathy diagnosis is -
Sweet syndrome
HSP
Purpura fulminans
Meningococcernia
1b
single
HSP a small vessel vasculitis is commonly seen in young males characterized by palpable purpura of dependent areas. It is associated with ahritis, gut vasculitis and glomerulonephritis. Page 309. Reference IADVL's concise textbook of dermatology
Dental
Autoimmune skin disorders
a66e138a-e2c5-426b-b0b7-813deee30dd3
All are seen in blunt injury of the eye except:
Hyphema
Iridocyclitis
Double perforation
Retinal detachment
2c
multi
Ans. Double perforation
Ophthalmology
null
5f6d00eb-9dd7-497e-b5f5-5cc596c4ddd2
Features of neurogenic shock are -
| Peripheral resistance | cardiac output
|Venous return | cardiac output
|Peripheral resistence | cardiac output
Venoconstriction | cardiac output
2c
single
NEUROGENIC SHOCK -,* Interruption of sympathetic vasomotor input after a high cervical spinal cord injury, *inadveent cephalad migration of spinal anesthesia, or * devastating head injury may result in neurogenic shock. In addition to aeriolar dilation, venodilation causes pooling in the venous system, which DECREASES ...
Medicine
C.V.S