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135
afe585cf-e3f9-48db-b638-2f86fd947200
Which of the following virus is from Herpes virus family?
Rubella
Measles
Rabies
EBV
3d
single
A VIRINAE B VIRINAE VIRINAE Includes HSV 1 HSV 2 HHV 3 Affects Ganglionic cells Includes HHV 5 HHV 6 HHV 7 Affects salivary glands Includes HHV 4 HHV 8 Affects B cells HHV - 3 - varicella zoster HHV - 4 - EBV HHV - 5 - Cytomegalo virus HHV - 8 - Kaposi saroma causing virus HSV - 1 - Herpes simplex virus 1 HSV - 2 - Her...
Microbiology
FMGE 2019
78696fc1-ccdd-4122-a5f3-3054b6c42c48
False about PCOS
High FSH/LH ratio
Bilateral ovarian cyst
Hirsutism
Increased risk of diabetes melitus
0a
multi
In PCOS, LH:FSH ratio is increased Shaw's Textbook of gynaecology,16th edition page no 432
Gynaecology & Obstetrics
PCOD, hirsutism and galactorrhea
542ea728-717b-43ba-bbb4-b5ab85637819
A 30-year-old male on methotrexate 7.5 mg once daily for arthritis attends clinic for starting family. Wife takes no other medication apart from OCP. What should be the advice before conceiving?
Husband should stop methotrexate and wife should continue contraception for 3 months
Husband should stop methotrexate and wife should continue contraception for 1 year
Wife should immediately conceive but husband should stop methotrexate
Adoption
0a
multi
Ans: A (Husband should stop methotrexate and wife should continue contraception for 3 months) Ref: Internet Source (e Therapeutic Guidelines Complete --Use of Anti-Rheumatic Drugs in Pregnancy) and Textbook of Management of Psoriasis by Nikhil YawalkarExplanation:Methotrexate interferes with the biosynthesis of purines...
Gynaecology & Obstetrics
Pathology of Conception
97b478bb-b924-480c-bb58-b6f35700ab42
Which of the following is considered the MOST impoant risk factor for necrotizing enterocolitis?
Perinatal asphyxia
Polycythemia
Prematurity
Respiratory distress syndrome
2c
single
Prematurity is the most impoant risk factor for necrotizing enterocolitis, although term infants also sometimes develop the condition. Clinical series have repoed that between 60 and 95% of affected babies are premature, and the incidence is markedly increased in babies born at lower gestational ages. Many other purpoe...
Pediatrics
null
c00eca28-e929-41f9-97a6-edb08106d48c
After how many days of ovulation embryo implantation occurs ?
3 - 5 days
7 - 9 days
10 - 12 days
13 - 15 days
1b
single
7 - 9 days "From the time a feilized ovum enters the uterine cavity from the fallopian tube (which occurs 3-4 days after ovulation) until the time ovum implants (7-9 days after ovulation) the uterine secretions called uterinemilk provide nutrition for the early dividing ovum" "At the time of implantation, on days 21-22...
Gynaecology & Obstetrics
null
ad292ad8-814e-4dac-8781-e0b0b232bb98
All of the following are clinical features of MEN-II EXCEPT: March 2004
Pituitary tumour
Phaeochromocytoma
Medullary carcinoma of thyroid
Neuroma
0a
multi
Ans. A i.e. Pituitary tumour Pituitary tumours are a pa of MEN-I/ Wermer syndrome
Pathology
null
dc5e91d9-440d-446a-9db9-d0540e0f4fa6
Type of collagen present in cornea ?
Type I
Type II
Type III
Type IV
0a
single
Ans. is 'a' i.e., Type I
Ophthalmology
null
4ae5e8a4-6143-40e7-a113-06ebeea2ec00
Caplan's syndrome is
Splenomegaly + Neutropenia
Rheumatoid Arthritis + Pneumoconiosis
Pneumoconiosis + Splenomegaly
Pneumoconiosis + Neutropenia
1b
single
Rheumatoid Arthritis + Pneumoconiosis nodules = Caplan's syndrome. Neutropenia + Splenomegaly + Nodular RA = Felty's syndrome.
Medicine
null
d7fc2573-7a4a-4902-82c2-bb4970ef708d
Parotid duct opens at
1st PM
1st molar
2nd upper molar
2nd lower molar
2c
single
null
Anatomy
null
6e8de49f-8b2c-4d53-b257-6776f209b9cd
Profunda femoris aery at its origin lies on which side of the femoral aery ?
Medial
Lateral
Posterior
Posteromedial
1b
single
Ans. is 'b' i.e., LateralProfunda femoris aery arises from lateral side of femoral aery about 4 cm below the inguinal ligament.
Anatomy
null
2ccede39-a077-45a2-b0ca-79e637bdaa59
A patient treated for infeility with clomiphene citrate presents with sudden onset of abdominal pain and distension with ascites the probable cause is
Uterine repture
Ectopic pregnancy rupture
Multifetal pregnancy
Hyperstimulation syndrome
3d
single
Ovarian Hyperstimulation syndrome It is an iatrogenic complication of ovulation induction with exogenous gonadotropins and clomiphene-induced cycles Charecteristic feature of OHSS is an increase in capillary permeability resulting in fluid shift from intravascular to extravascular spaces Mechanism of Action Probably me...
Gynaecology & Obstetrics
Reproductive physiology and hormones in females
5a7a4b63-18f2-4dc2-91ac-35c8c4e4fab0
A 42-year-old man presents with long-standing abdominal pain after meals, which is relieved by over-the-counter antacids. The patient has lost 9 kg (20 lb) in the past year. Physical examination reveals peripheral edema and ascites. Laboratory studies show decreased serum albumin but normal serum levels of transaminase...
Atrophic gastritis
Enlarged rugal folds
Intestinal metaplasia
Multiple hemorrhagic ulcers
1b
single
Menetrier disease /Hyperplastic hypersecretory gastropathy Mean age 30-60 years Rare disorder associated with excessive secretion of transforming growth factor (TGF)-a, which is an EGF receptor (EGFR) ligand, and hyperactivation of the epidermal growth factor receptor on gastric epithelial cells. Excessive EGFR activat...
Pathology
Systemic Pathology
f3a3d766-3bf6-4a5b-b273-99bac02ec613
A middle-aged male comes to the outpatient depament (OPD) with the only complaint of hoarseness of voice for the past 2 years. He has been a chronic smoker for 30 years. On examination, a reddish area of mucosal irregularity overlying a poion of both cords was seen. Management would include all except:
Cessation of smoking
Bilateral cordectomy
Microlaryngeal surgery for biopsy
Regular follow-up
1b
multi
The mentioned symptoms indicate that either it is pachydermia laryngitis or it can be early carcinoma: Both the conditions can be distinguished by biopsy only In either conditions: smoking is a causative factor and should be stopped. Regular follow up is a must in either of the conditions. Bilateral cordectomy is not r...
ENT
null
1f4a594c-c7ca-4253-b07c-fd3e5e94c2f6
Antibody found in patients of myaesthenia gravis is directed against
Acetycholine
Acetycholine receptors
Acetycholine vesicles in nerve terminal
Actin-myosin complex of the muscle
1b
single
*myasthenia gravis is an autoimmune disease,most commonly caused by antibodies to acetylcholine receptors in the post junctional membrane of the neuromuscular junction ,which are found in around 80%of affected patients. Ref Harrison20th edition pg 2378
Medicine
C.N.S
68933803-90b4-4008-9097-ed8a15b02fc5
All are true foe annular pancreas except
Upper GI series is IOC
Duodenal obstruction present
ERCP is done
Non - rotation of gut
0a
multi
upper GI series is not the investigation of choice.They are plain X-ray abdomen,ERCP and Radioscopic study , Barium meal. SRB,5th,712
Surgery
G.I.T
c38bf251-62b7-4aaa-a391-c104dcc87a40
Which of the following liver enzymes is predominantly mitochondrial?
SGOT (AST)
SGPT (ALT)
GGT
5' Nucleotidase
0a
single
In old literature, it was called as serum glutamate oxaloacetate transaminase (SGOT). AST needs pyridoxal phosphate (vitamin B6) as co-enzyme. Normal serum level of AST ranges from 8 to 20 U/L. It is a marker of liver injury and shows moderate to the drastic increase in parenchymal liver diseases like hepatitis and mal...
Biochemistry
Enzymes
37d870d9-1b0a-4bad-8baf-9223fce09cbd
The normal P wave is biphasic in lead
V1
LII
aVF
aVR
0a
single
The normal P wave in lead V1 may be biphasic with a positive component reflecting right atrial depolarization, followed by a small (<1 mm2 ) negative component reflecting left atrial depolarization. Ref Harrison 20th edition pg 1455
Medicine
C.V.S
258fb8d5-2be6-4c4f-b023-cf231449cbef
Mycosis cells are altered :
T Lymphocytes
Monocytes
b lymphocytes
Eosinophils
0a
single
A. i.e. T lymphacytis
Skin
null
2fe94907-eb3f-4324-ac4d-27b97ae7ea7b
Following periodontal surgery the epithelial attachment healing is completed in
2 weeks
4 weeks
6 weeks
8 weeks
1b
single
null
Dental
null
4a8ec7c2-185c-4f2f-a233-d4bd3d8513b3
All of the following are indices to define obesity, EXCEPT:
Chandler's index
Corpulence index
Quetlet's index
Body mass index
0a
multi
Various indices used to detect obesity include: Corpulence index Quetlet's index/ Body mass index Ponderal index Broca index Lorentz's formula Ref: Park 21st edition, page 369.
Social & Preventive Medicine
null
8b98449b-b9ee-42db-b2b0-17b6434aad96
Surfactant appears in amniotic fluid at the gesta?tional age of :
20 weeks
32 weeks
36 weeks
26 weeks
1b
single
Ans. is b i.e. 32 weeks Friends, I had to search a lot for this answer but all in vain. Only Nelson Paediatric throws some light on this issue : "Pulmonary surfactant is a heterogenous mixture of phospholipids and proteins secreted into the saccular or alveolar sub-phase by the type ll pneumocytes. Its presence is firs...
Gynaecology & Obstetrics
null
61509fe3-5949-45a7-9627-ca61a26a8214
For termination of pregnancy, consent is needed from
Only woman
Only husband
Both paners
Consent not needed
0a
multi
Pregnancy can only be terminated on the written consent of the woman. Husband's consent is not requiredPregnancy in a minor girl (below the age of 18 years) or lunatic cannot be terminated without written consent of the parents or legal guardianReference: Textbook of Obstetrics; Sheila Balakrishnan
Gynaecology & Obstetrics
General obstetrics
7a075a1c-d492-4f80-8481-ac8a6ca159db
The usefulness of a 'screening test' in a community depends on its -
Sensitivity
Specificity
Reliability
Predictive value
0a
single
Screening refer to 'the search for unrecognized disease or defect by means of rapidly applied tests, examinations or other procedures in apparently healthy individuals' For screening a disease the most important parameter is sensitivity Sensitivity is defined as the ability of a test to identify correctly all those wh...
Social & Preventive Medicine
null
77960df3-f4d1-4fea-91ae-f47f4f8b6ad6
The laryngeal mask airway used for securing the airway of a patient in all of the following conditions except:
In a difficult intubation
In cardiopulmonary resuscitation
In a child undergoing an elective/routine eye surgery
In a patient with a large tumour in the oral cavity
3d
multi
D i.e. In a patient with large tumor of the oral cavity
Anaesthesia
null
886ee69b-3aeb-4bc5-bca5-d95b700f817c
Ratio of lung weight to body weight is calculated in
Fodere's test
Plocquet's test
Breslau's second life test
All of the above
1b
multi
Plocquet's test is one of the tests for live birth. Before respiration: Ratio of lung weight to body weight is I/70. After respiration: Ratio is 1/35.
Forensic Medicine
null
445393f3-46ba-4530-8433-c190a3c8b93c
Which of the following is a false physical parameter during pregnancy?
It's a prothrombotic condition
Blood fibrinogen levels are increased
Clotting and bleeding times are reduced
There is lowering of serum protein levels
2c
multi
On an average the non pregnant levels of blood fibrinogen is 260mg%. But in pregnancy it can reach an average value of 388 mg% (288 - 576 mg%) even then the clotting and bleeding times remains unchanged. Ref: Mudaliar and Menon's Clinical Obstetrics, 9th Edition, Page 41.
Gynaecology & Obstetrics
null
83715a2b-a224-4d3f-8e76-e09833be90d0
Chocolate agar is ?
Basal medium
Enrichment medium
Enriched medium
Simple medium
2c
single
Ans. is 'c' i.e., Enriched medium
Microbiology
null
762d06b7-e6a0-4103-a6b0-b8f0671c36b6
Asprin is not given in a patient who is already on heparin because aspirin causes :
Platelet dysfunction
Aspirin inhibits the action of heparin
Enhanced hypersensitivity of heparin
Therapy of heparin cannot be monitored
0a
single
null
Pharmacology
null
35263021-5b59-43ea-99cc-76cf015b1219
Which of these is the characteristic feature of membranoproliferative glomerulonephritis-
Sub epithelial deposits
Foamy cells
Splitting of glomerular basement membrane
Sub endothelial deposits.
2c
single
Ans. is 'c' > 'd' ie splitting of glomerular basement membrane > sub endothelial deposits Both the features mentioned in the options d & c are present in membranoproliferative glomerulonephritis.Membranoproliferative glomerulonephritis is of 2 typesTYPE I characterized byDeposition of subendothelial* immune on complexe...
Pathology
Glomerular Diseases
50c9ed23-19a7-480d-950a-973876d73c50
Main hormone acting upon uterus to initiate labor-
Oxytocin
Estrogen
Progesterone
Cortisole
0a
single
Ans-A i.e., Oxytocin Oxytocino Oxytocin is a nonapeptide,o It is secreted by the posterior pituitary along with vasopressin (ADH).o Both oxytocin and ADH are synthesized within the nerve cell bodies in the supraoptic and paraventricular nuclei of the hypothalamus; are transported down the axon and stored in the nerve e...
Unknown
null
aa68d709-b4b6-4186-8ad1-42f7f3f437c9
Non -sterile hypopyon is seen in -
Pneumococcus infection
Pseudomonas infection
Fungal infection
Gonococcal infection
2c
single
In fungal ulcer, usually a big hypopyon is present even if the ulcer is small.Unlike the bacterial ulcer,the hypopyon may not be sterile as the fungi can penetrate into the anterior chamber without perforation. Reference:Comprehensive ophthalmology,AK Khurana,6th edition,page no.106
Ophthalmology
Cornea and sclera
9b491862-490f-455a-8ce2-f009684cb999
A highly specific inhibitor that targets the phosphorylation activity of TFIIH is added to an in vitro transcription reaction. Which one of the following steps is most likely to be affected?
Binding of RNA polymerase to promoter sequence
Promoter clearance
Recruitment of TFIID
Open promoter complex formation
1b
multi
Most likely to be affected by inhibitor that targets the phosphorylation activity of TFIIH is promoter clearance Transcription factor II H has two activities : Helicase Kinase -Unwinds the DNA -Phosphorylates the TFIIH- Promoter clearance.
Biochemistry
Transcription
c4326fc2-da43-4eef-86b2-2f6b7945eb13
Occlusal morphology is given by:
Okeson
Bencher
Kennedy
Knol
0a
single
null
Dental
null
12857153-7f3a-4555-903e-b514d8b9f9ba
All of the following histopathological changes are seen in psoriasis except?
Hyperkeratosis
Acanthosis
Dyskeratosis
Parakeratosis
2c
multi
Dyskeratosis is premature &abnormal keratinization below the level of stratum corneum,seen in Bowen's disease,SCC,Dyskeratosis congenita.
Dental
null
c79aae07-b997-4c94-8807-90fb1297819d
X-ray of a patient shows the following changes: Bulbous ends of long bones, normal appositional bone growth and there is failure of physiologic root resorption. Lab finding shows myelophthisic anemia. What can be the probable diagnosis?
Fibrous dysplasia
Osteomyelitis
Osteopetrosis
Paget's disease
2c
single
OSTEOPETROSIS: Roentgenographic features: Medullary cavities are replaced by bone and the cortex is thickened. Density of bone may be such that, the roots of the teeth are nearly invisible on dental roentgenogram. Ends of long bones are bulbous called Erlenmeyer's flask deformity. In osteopetrosis, there is normal app...
Pathology
null
3c21f444-3630-4021-8c51-26ab483d116b
A 70-year-old male has a pathologic fracture of femur. The lesion appears a lytic on X-rays film with a circumscribed punched out appearance. The curetting from fracture site is most likely to show which of the following?
Diminished and thinned trabecular bone
Sheets of atypical plasma cells
Metastatic prostatic adenocarcinoma
Malignant cells forming osteoid bone
1b
single
Old patient along with lytic circumscribed punched out X-ray appearance suggests multiple myeloma Multiple myeloma most often presents as multifocal destructive bone tumors composed of plasma cells throughout the skeletal system. It shows sheets of atypical plasma cells.
Pathology
Plasma Cell Disorders and Multiple myeloma
9d40c400-1f32-4a65-9ea9-e3e4c3c3c84a
Not a common complication of hemithyroidectomy
Hypoparathyroidism
Reactionary hemorrhage
Recurrent laryngeal nerve palsy
External laryngeal nerve palsy
0a
single
As parathyroids on the opposite side are preserved and not dealt with during surgery hypoparathyroidism is not seen after hemithyroidectomy.
Surgery
All India exam
ed366945-d705-4c75-8cea-4bf202fec9a5
Diet given to pregnant lady under ICDS is
3000Kcal with 60grams of protein
800Kcal with 25grams of protein
500Kcal with 12grams of protein
600Kcal with 18grams of protein
3d
single
In ICDS supplementary nutrition is given to children below 6 years, nursing and expectant mothers from low-income group.Each child 6-72 months of age get 500 Cal and 12-15Gm of proteinSeverely malnourished child 6-72 months of age get 800 Cal and 20-25Gm of proteinEach pregnant and nursing women to get 600 Cal and 18-2...
Social & Preventive Medicine
Maternal and child care
4a78e035-14d9-4ca6-9680-9e30bfe5f9a4
Pulpotomy is not indicated in-
Small pulp exposure since 1 hour
Pulp exposure in permanent tooth with open apex
Pulp exposure in permanent tooth with closed apex treated immediately after injury
Insufficient crown structure remaining
0a
multi
If the patient is seen within an hour or two after the injury, if the vital exposure is small, and if  sufficient crown remains to retain a temporary restoration to support the capping material and  prevent the ingress of oral fluids, the treatment of choice is direct pulp capping.  If the pulp exposure in  a traumatized,...
Dental
null
7115dcf8-3997-48ac-9899-c8d052c56126
The site at which 1,25-hydroxylation of Vitamin-D takes place in the kidneys is:
Collecting ducts
Glomerulus
Proximal convoluted tubules
Distal convoluted tubules
2c
single
Proximal convoluted tubules
Physiology
null
f7d17358-64c7-4deb-9cea-16c5d5b38d78
Pharyngoconjunctival fever is caused by -
Adenovirus 3 and 7
Adenovirus 11, 21
Adenovirus 40, 41
Adenovirus 8, 19
0a
single
Pharyngoconjunctival fever is caused most commonly by serotypes 3 and 7, but serotypes 2, 4 and 14 also, have been documented as etiologic agents.  Ocular infections caused by Adenovirus - i. Epidemic keratoconjunctivitis → Serotypes 8, 19, 37 ii. Follicular conjunctivitis → Serotypes 3,7 iii. Pharyngoconjunctival f...
Microbiology
null
e7997f2a-8855-4953-b749-8130dd76c2c5
Emergency contraceptive drugs are:
Levo-norgestrel
Estrogen + progesterone
Mifepristone
All of the above
3d
multi
Postcoital (emergency) contraception : 1. Levonorgestrel 0.5 mg + ethinylestradiol 0.1mg taken as early as possible but within 72 hours of unprotected intercourse and repeated after 1 2 hours. Progesterone and estrogen combination can also be used in emergency contraception. 2. levonorgestrel 3. ulipristal 4. mifeprist...
Pharmacology
Endocrinology
25ece4f5-1cd5-4043-a29d-73b48705c362
The following are features of primary hyperladosteronism EXCEPT: March 2013
Polyuria
Hypeension
Hypokalemia
Hyperkalemia
3d
multi
Ans. D i.e. Hyperkalemia Conn's syndrome 3asic pathology: Hyperaldosteronism Features: - Hypeension, - Decreased K., - I-olyuria, - Poiydypsia and - Proximal myopathy
Medicine
null
04b969f1-dda2-4a4b-8c12-284b3a619f5d
Ring sequestrum causes:
Typhoid osteomyelitis
Chronic osteomyelitis
Amputation stump
Tuberculosis osteomyelitis
2c
single
Sequestrum is the dead bone separated out from the living bone by the granulation tissue. The factors responsible for bone death in chronic osteomyelitis are: raised intravascular pressure Vascular stasis and small vessel thrombosis periosteal stripping bacterial toxins Sequestrum is the hall mark of chronic osteomyeli...
Orthopaedics
Joint and Soft tissue infections
57395979-66b0-4198-bf4c-23043f6924cf
Following represents fetal hypoxia except:
Excessive foetal movements
Meconium in vertex presentation
Fetal scalp blood pH > 7.3
Heart rate < 100
2c
multi
Normal fetal scalp pH ranges from 7.25 to 7.35. Fetal hypoxia is indicated by ‘acidosis’ or fall in fetal scalp pH to values below normal (Not by increase). It is used to corroborate the significance of fetal CTG (Cardiotocography). Interpretation of Fetal Scalp blood sampling
Gynaecology & Obstetrics
null
ad4d2ea2-4139-4e89-8990-e7e4a5eeaf85
Which of the following has the highest cholesterol content
chylomicrons.
intermediate-density lipoproteins (IDLs).
LDL.
HDL.
2c
single
null
Physiology
null
053adcb3-b843-4568-af0e-ad8ff005bc99
Incubation period of herpes zoster is
7-14 days
1 month
1-2 years
3-6 months
0a
single
null
Microbiology
null
6b3a5bd8-29ae-471f-a887-484621447d46
Which of the following is physiological uncoupler-
Thermogonin
2, 4nitrophenol
2, 4Dinitrophenol
Oligomycin
0a
single
Ans. is 'a' i.e.* Thermogenin o Amongst the given options, a, b and c are uncouplers.o However, only thermogenin, among these three is a natural (physiological) uncouplex.Uncoupleso As the name suggests, these componds block the coupeling of oxidation with phosphorylation. These compounds allow the transfer of reducing...
Biochemistry
Respiratory Chain
6bad93ce-f227-415b-b299-fa8c7c82fd80
Most common mode of treatment for laryngomalacia is:
Reassurance
Medical
Surgery
Wait and watch
0a
single
In most patients laryngomalacia is a self-limiting condition. Treatment of laryngomalacia is reassurance to the parents and early antibiotic therapy for upper respiratory tract infections. Tracheostomy is required only in severe respiratory obstruction. Surgical intervention (supraglottoplasty i.e. reduction of redunda...
ENT
null
9aed191e-4ca7-4aa4-bb58-8d444b704552
Sensory fiber with least conduction velocity:September. 2005
C- fiber
Alpha fiber
beta fiber
Gamma fiber
0a
single
Ans. A: C- fiberAlpha fibers are the thickest (fiber diameter of 12-20 micrometer) and fastest conduction velocity (of 70-120 mis) whereas C-fibers are the thinnest (fiber diameter of 0.3-1.2 micrometer) and slowest conduction velocity (of 0.5-2 m/s)
Physiology
null
e74349c7-0d7c-4cab-9472-38dbfd4c16dc
Which of these structures appears radiopaque?
Maxillary sinus
Nasal fossa
Nasal septum
Mental foramen
2c
single
Radiopaque refers to that portion of the radiograph that appears light or white. Radiopaque structures are dense and absorb or resist the passage of the X-ray beam, E.g., Enamel, dentin and bone. Nasal septum On the panoramic radiograph, it appears as a vertical radiopaque partition that divides the nasal cavity. Refer...
Radiology
null
9d2117b0-8fd7-4dd6-8792-fbd5c558b7a8
Coliform test is for -
Air pollution
Water contamination
Sound pollution
None
1b
multi
Ans. is 'b' i.e., Water Contomination Bacteriological indicators of w ater contaminationo Presence of following organism indicate fecal contamination of water.Coliform : by all practical point of view it is assumed that all coliform are fecal in origin unless a non-fecal origin can be proved.Fecal streptococci or enter...
Social & Preventive Medicine
Environment and Health
d4f8ccc1-bb25-4209-a951-725d03dd72ad
Seoli cell secrets
Androgen binding protein
Testosterone
LH
FSH
0a
single
Androgen binding protein is a protein secreted by testicular Seoli cells along with inhibin and mullerian inhibiting substance. Androgen binding protein probably maintains a high concentration of androgen in the seminiferous tubules.Ref: Ganong&;s review of medical physiology; 24th edition; page no: 421
Physiology
Endocrinology
d7b0c506-5aba-47c4-8314-f083e0c93216
High plasma protein binding of a drug results in:-
Decreased glomerular filtration
High volume of distribution
Lowers duration of action
Less drug interaction
0a
single
* High plasma protein binding (PPB) of a drug decreases its distribution into tissue and thus lower the volume of distribution. * As only free drug can be metabolized or excreted, high PPB usually increases the duration of action. * With higher PPB, there is more chance of getting displaced by other drugs leading to mo...
Pharmacology
Pharmacokinetics
c5e38b06-c1a5-4b15-a1f6-15c60046906a
Polypeptide capsule is seen in
Corynebacterium diphtheriae
Clostridium welchii
Staphylococcus aureus
Bacillus anthracis
3d
single
null
Microbiology
null
addb09aa-0799-4052-a66c-908012e726b7
Earliest fetal anomaly to be detected by USG: March 2013
Hydrocephalus
Achndroplasia
Anencephaly
Spina bifida
2c
single
Ans. C i.e. Anencephaly
Gynaecology & Obstetrics
null
a8b70198-2795-4dcd-a6f8-2066403c55f2
Treatment of depression with suicidal tendencies is?
Clozapine
Mitrazapine
ECT
Olenzapine
2c
single
ANSWER: (C) ECTREF: Kaplan synopsis 10th ed p. 557ECT is therapy of choice depression with:Suicidal tendencyPsychomotor retardationPsychotic and delusional features with somatic syndromeIntolerance , contraindication, refractory to drugs
Psychiatry
Pharmacotherapy Management of Children and Adolescents
9828fcb3-3ef9-46e3-89bb-ae0011bfb255
A 32 year old male presents with a laceration he sustained after stepping on broken glass at the beach. The examination reveals an 8cm cut on the medial plantar aspect of the left foot. Which peripheral nerve block is appropriate?
Saphenous nerve
Sural nerve
Posterior tibial nerve
Superficial peroneal nerve
2c
multi
Posterior tibial nerve * The posterior tibial nerve innervates the sole of the foot. To perform a peroneal nerve block, 1 percent lidocaine is injected into the subcutaneous tissue lateral to the posterior tibial aery at the upper border of the medial malleolus. * None of the other nerves listed supply the plantar surf...
Surgery
null
3847c743-34e9-4c9d-a493-21582033a3f4
Complication of positive pressure ventilation –
Pneumothorax
Bradycardia
Decreased ventilation
Arrhythmias
0a
single
PEEP & CPAP can cause barotrauma which may result in pneumothorax, pneumoperitoneum, penumopericardium/ cardiac tamponade.
Anaesthesia
null
f10fe683-0482-41ec-8387-a275cadddc1b
The most common cause of conductive deafness in children is
ASOM
Wax
Serous otitis media
Otosclerosis
2c
single
SEROUS OTITIS MEDIA, SECRETORY OTITIS MEDIA, MUCOID OTITIS MEDIA, "GLUE EAR" This is an insidious condition characterized by accumulation of nonpurulent effusion in the middle ear cleft. The fluid is nearly sterile. The disease affects children of 5-8 years of age. Hearing loss. This is the presenting and sometimes the...
ENT
Ear
8517f45a-abf9-4048-b2a3-072e2d92116b
Drug of choice in absence seizure-
Carbamazepine
Phenytoin
ACTH
Ethosuximide
3d
single
Ans. is 'd' i.e., Ethosuximide
Pediatrics
null
14a9d171-cee5-4ffa-a67c-f2e441af2daa
A young girl has had repeated infections with Candida albicans and respiratory viruses since the time she was 3 months old. As pa of the clinical evaluation of her immune status, her responses to routine immunization procedures should be tested. In this evaluation, the use of which of the following vaccines is contrain...
Diphtheria toxoid
Bordetella peussis vaccine
Tetanus toxoid
BCG
3d
single
Recurrent severe infection is an indication for clinical evaluation of immune status. Live vaccines, including BCG attenuated from Mycobacterium tuberculosis, should not be used in the evaluation of a patient's immune competence because patients with severe immunodeficiencies may develop an overwhelming infection from ...
Microbiology
Immunology
fe2e1548-36ce-49a6-b6b5-19254bbf113e
Choanal atresia is due to the persistence of
Bucconasal membrane
Oropharyngeal membrane
Laryngotracheal fold
Tracheoesophageal fold
0a
single
Choanal atresia Choana, also called posterior nares, is an opening in the posterior part of each nasal cavity, through which the nasal cavity communicates with nasopharynx. Choanal atresia is a congenital anomaly characterized by closure of one or both posterior nasal cavies (i.e., choana). It is due to the persistenc...
ENT
null
aefdead6-93f1-4b03-9a6e-b3f83650e659
Cells seen at the function between two layers ofplacenta are?
Hofbauer cell
Hofmann cells
Amniogenic cells
Uterine natural killer cells (UNK)
0a
single
Ans. is'a'i.e., Hofbauer cellHofbauer cells (HBCs) are placental macrophages that are present in the core of villus.Major cell type in placenta include syncytiotrophoblasts which line intervillous space and are in direct contact of maternal blood.Underlying stromal cells adjacent to fetal capillaries largely consisting...
Gynaecology & Obstetrics
null
bf6b9832-8c15-4a34-a58a-3b00f8e487e5
Mode of excretion of cyclophosphamide is -
Lung
Liver
Kidney
Skin
2c
single
Ans. is 'c' i.e., Kidney [Ref: style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif; margin: 0 0 8pt 8px; text-indent: 0; text-align: left">o Cyclophosphomide is primarily metabolized (80%) and metabolites are excerted in urine.o 10 to 20% is excreted unchanged in urine and 4% is excreted in...
Pharmacology
Anti-Neoplastic Agents
3b66b489-d00c-4d11-b418-bf8c54eb9d8e
HPV with low risk sexually transmitted types include
6 & 11
16 & 18
26 & 53
73 & 82
0a
multi
(A) 6 & 11# GENITAL INFECTIONS: Since cervical and female genital infection by specific HPV types is highly associated with cervical cancer, those types of HPV infection have received most of the attention from scientific studies.> HPV infections in that area are transmitted primarily via sexual activity.> Of the 120 k...
Skin
Miscellaneous
9b1b7698-0bc5-4606-9a1c-2c71aba0fcc8
Infection by which virus gives rise to the following skin lesions?
Herpesvirus
Measles virus
Varicella zoster virus
Parvovirus
2c
single
c Varicella zoster virusSimultaneous presence of various types of skin lesions including macules, papules & vesicles are suggestive of Chicken Pox', caused by Varicella zoster virus
Pediatrics
General Considerations - Infectious Diseases
30f00c67-b7e1-433a-9a03-1636378a12de
Action of Antidote of heparin (Protamine) is based on:
Competitive antagonism
Chemical antagonism
Non competitive antagonism
Toxic reaction
1b
single
Chemical antagonism
Pharmacology
null
9ef8c88a-4de3-4b89-b2a9-28586dd05628
Breast milk storage in a refrigerator is upto ?
4 hrs
8 hrs
12 hours
24 hrs
3d
single
Ans. is 'd' i.e., 24 hrs Breast milk o Can be stored at room temperature --> For 8-10 hours o In a refrigerator --> For 24 hours o In a freezer --> -20degc for 3 months
Pediatrics
null
d6db73bc-a8a2-4442-8aca-d34f2b52d3c1
Currarino triad includes:
Pre-sacral meningocele + Sacral defect + Tethered cord
Ectopia vesicae + Anorectal malformation + Sacrococcygeal osseous defect
Anorectal malformations + Sacrococcygeal osseous defect + Presacral mass
Tethered cord + Anorectal malformations + Ectopia vesicae
2c
single
Currarino triadorASP triad: - Anorectal malformation or congenital anorectal stenosis - Sacrococcygeal osseous defect (always present) - Classically, hemisacrum with intact first sacral veebra ("sickle-shaped sacrum") - Mild (hypoplasia) to severe (agenesis) of sacrum and coccyx - Presacral mass (various types) - Anter...
Surgery
Oncology
42a30553-2592-47b5-bbb4-094d6f343179
The International Neuroblastoma Staging System (INSS) stage 4S includes metastasis to all the following except
Liver
Skin
Bone marrow
Bone
3d
multi
INSS stage 4S refers to neuroblastoma in children younger than 1 yr of age with dissemination to liver, skin, and/or bone marrow without bone involvement and with a primary tumor that would otherwise be staged as INSS stage 1 or 2. Reference: Nelson; Neuroblastoma; Page no: 2463
Pediatrics
Childhood tumors
883904fc-e3c3-47d1-b1c3-26113f0b1ee8
Anuria is defined passing Less than _____ ml urine/day
400ml
3L
100ml
1000ml
2c
single
Anuria  <100ml. Oliguria  < 400ml.
Medicine
null
3e98d532-5ed4-4224-b483-f243beaf16fd
At the superficial inguinal canal increased abdominal pressure leads to closure by approximation of crura in the opening. This defect is seen in an aponeurosis formed by which of the following muscles?
Fascia tranversalis
External oblique
Internal oblique
Erector spinae
1b
single
Ans. is'b'i.e., External oblique(Ref: BDC &/e Vol. II p. 212, 213; Ramesh Babu p. 219)Examinar is asking about superficial inguinal ring which is triangular defect in external oblique aponeurosis.Superficial inguinal ring is an anatomical structure in the anterior abdominal wall. It is a triangular shaped defect in the...
Anatomy
null
8d4bec16-cfa0-4df9-a4ea-c822526ec76b
Heller's myotomy is done for: September 2007, 2009, 2010
Esophageal carcinoma
Pyloric hyperophy
Achalasia cardia
Inguinal hernia
2c
single
Ans. C: Achalasia cardia Achalasia is associated with loss of ganglion cells in the esophageal myenteric plexus. These impoant inhibitory neurons induce LES relaxation and coordinate proximal-to-distal peristaltic contraction of the esophagus Achalasia is an esophageal motor disorder characterized by increased lower es...
Surgery
null
b6b8d13c-ec39-45a4-814a-553b3e56f8c4
Proton pump inhibitors suppress gastric add secretion by inhibition of-
H+/Cl- ATPase pump
H+/ K+ ATPase pump
Na/Cl- ATPase pump
Na+/K+ ATPase pump
1b
single
null
Unknown
null
3ecac067-48bf-44a4-afba-9512751ce904
Which of following anatomical information may assist you during post-partum tubal sterilization.
Fallopian tube lies anterior to round ligament.
Round ligament lies anterior to fallopian tube.
Uteroovarian ligament lies anterior to round ligament.
Fallopian tube lies posterior to uteroovarian ligament.
1b
multi
Round ligament originates below and anterior to origin of fallopian tube.
Gynaecology & Obstetrics
null
8cfc30cb-fa60-4509-83f1-006e62168b3d
Features of alcoholic liver disease -
Fatty changes
Pericellular fibrosis
Mallory bodies seen
All
3d
multi
Ans. is AllPathology of alcoholic liver diseaseSteatosis (fatty liver)o Microvesicular fatty change o Later changes to macrovesicular fatty changeAlcoholic hepatitiso Hepatocellular necrosis o Ballooning degeneration o Mallory bodieso Neutrophilic infiltration Perivenular and perisinusoidol fibrosis --*central hyaline ...
Pathology
null
24926ac8-e575-44a8-b426-b22e99e527a5
Which of the following is the commonest tumour of thyroid -
Anaplastic carcinoma
Follicular carcinoma
Papillary carcinoma
Medullary carcinoma
2c
single
Ans. is 'c' i.e., Papillary 'Papillary carcinoma accounts for 80% of all thyroid malignancies in iodine-sufficient areas and is the predominant thyroid cancer in children and individuals exposed to external radiation." - SchwartzIncidence of primary malignant tumors of thyroid gland (Harrison 17/e)Type of thyroid carci...
Surgery
Thyroid Malignancies
e5b691d7-fd28-489b-9a45-6150ed49612e
SVC syndrome is most commonly associated with:
Mediastinal fibrosis
Lymphoma
Lung cancer
TB mediastinitis
2c
single
If the superior or inferior vena cava is obstructed, the venous blood causes distention of the veins running from the anterior chest wall to the thigh.The lateral thoracic vein anastomoses with the superficial epigastric vein, a tributary of the great saphenous vein of the leg. In these circumstances, a touous varicose...
Anatomy
null
9e038a3c-f6b8-47bb-ac4d-8455955ab6d0
There is a pressure sore extending into the subcutaneous tissue but underlying structures are not involved. Stage of the pressure sore is
Stage 1
Stage 2
Stage 3
Stage 4
2c
single
Stage 1Non-blanchable erythema without a breach in theepidermisStage 2Paial-thickness skin loss involving the epidermis and dermisStage 3Full-thickness skin loss extending into the subcutaneous tissue but not through underlying fasciaStage 4Full-thickness skin loss through fascia with extensive tissue destruction, mayb...
Surgery
General surgery
c5a90bfb-c634-455e-a6d8-c1f330bd857c
The fluidity of the plasma membrane is increased by
Arachidonic acid
Cholesterol
Palmitic acid
Stearic acid
0a
single
Cholesterol maintains the fluidity of the membrane. Cholesterol acts as a buffer to modify the fluidity of membranes. A lipid bilayer made up of only one type of phospholipid changes from a liquid state to a rigid crystalline state (gel state) at a characteristic freezing point. This change in state is known as a phase...
Physiology
General physiology
cfd01954-7882-4226-920e-7ce274942686
The hard carious dentin is removed with
Excavator
Bur at Low speed
Bur at high speed
None of the above
2c
multi
null
Dental
null
a0437225-5c70-4bd7-87b3-050872f3dcc8
In transverse lie, the presentation is:
Veex
Breech
Brow
Shoulder
3d
single
Transverse lie The long axes of the fetal and maternal ovoid are approximately at right angles to each other and the shoulder is presenting at pelvic inlet.The baby may be directly across the mother&;s abdomen,when it is a transverse lie,or obliquely across with the head or breech in one iliac fossa ,when it is an obli...
Gynaecology & Obstetrics
Abnormal labor
0dfddde1-0368-421b-b97e-f42b21013b26
Infection of CNS spreads to inner ear through
Cochlear aqueduct
Endolymphatic sac
Vestibular aqueduct
Hyle fissure
0a
single
The scala tympani is closed by a secondary tympanic membrane. It is also connected with subarachnoid space through aqueduct of cochlea Reference: Dhingra 6th edition.
ENT
Ear
80e6faab-60ec-42f1-9ab2-09a339cad8f5
Resting membrane potential of a neuron is
-9mV
-50mV
-70mV
-100mV
2c
single
In neurons, the resting membrane potential is usually about - 70mV, which is close to the equilibrium potential for K+. Because there are more open K+channels than Na+ channels at rest Ref: Ganong&;s Review of medical physiology;25th edition; pg: 90
Physiology
Nervous system
3bc487df-97f4-4e75-af7e-ce46ab5e1969
All of the following are true about Cholesterol Ester Transfer Protein(CETP) , EXCEPT:
Associated with HDL
Facilitates the transfer of cholesterol ester from HDL to LDL
Facilitates the transfer of triacylglycerol from LDL to HDL
Facilitates the transfer of triacylglycerol from HDL to LDL
3d
multi
Cholesterol ester transfer protein (CETP): Facilitates the transfer of cholesterol ester from HDL to VLDL, IDL and LDL in exchange for triacylglycerol. Relieves the product inhibition of the LCAT enzyme.
Biochemistry
Lipoproteins
0ebde6da-7495-407d-b9df-d640a5960cc9
A 27 year old man develops bilateral parotid gland swelling and orchitis, and is generally ill with fever of 102deg F. Which of the following substances is most likely to be significantly elevated in the patient's serum?
Alanine aminotransferase (ALT)
Amylase
Aspaate aminotransferase (AST)
Ceruloplasmin
1b
multi
The disease is mumps, caused by a paramyxovirus. In children, mumps causes a transient inflammation of the parotid glands, and less commonly, the testes, pancreas, or central nervous system. Mumps tends to be a more severe disease in adults than in children. Mumps in adults involves the testes (causing orchitis) and pa...
Microbiology
null
3577e966-c297-49fb-bec4-0df5b963ba3e
The MR imaging in multiple sclerosis will show lesions in:
White matter
Grey matter
Thalamus
Basal ganglia
0a
single
A i.e. White matter
Radiology
null
4606b481-62b4-4441-bafa-2ba5bac58e5d
Duroziez's sign is seen in
Aoic regurgitation
Tricuspid regurgitation
Mitral stenosis
Carcinoid syndrome
0a
single
Ref Harrison 19 th ed pg 1536 booming "pistol-shot" sound can be heard over the femoral aeries (Traube's sign), and a to-and-fro murmur (Duroziez's sign) is audible if the femoral aery is lightly compressed with a stethoscope.
Medicine
C.V.S
33d60b9b-c221-4993-be25-faaeef829d8a
The yeast which shows thick gelatinous capsule and positive for mucicarmine is
Cryptococcus neoformans
Histoplasmosis
Blastomycosis
Paracoccidiomycosis
0a
single
null
Pathology
null
226bf456-c696-41d0-91ae-076710b27aab
Not a sign of blunt trauma?
Sphincter tear
angle recession
Corneal perforation
Retinal dialysis
2c
single
Rings of Trauma: Hidden signs of Blunt trauma 1.Central Iris: Sphincter Tear 2.Peripheral Iris: Iridodialysis 3.Anterior Ciliary body: Angle recession 4.Separation of ciliary body from scleral spur: Cyclodialysis 5.Trabecular Meshwork: Trabecular Meshwork tear 6.Zonule/ lens: Zonular tear with possible lens subluxation...
Ophthalmology
Trauma
a3b727ae-d59e-4cf6-a8c8-7b883fe2b4dc
Following constitute dietary fibres except :
Pectin
Cellulose
Hemicellulose
Riboflavin
3d
multi
D i.e. Riboflavin
Physiology
null
756e520d-da5c-4681-9b95-808ab10e2585
A patch test is what type of hypersensitivity?
Type 4
Type 1
Type 2
Type 3
0a
single
HYPERSENSITIVITY REACTIONS
Pathology
null
4532efdd-cb38-4516-bbd7-dc6554b07502
Ganglion of tendons is an example of -
Neoplastic process
Malformation
Amyloid deposition
Myxomatous degeneration
3d
single
Ganglion A ganglion is a small cyst located near a joint capsule or tendon sheath. A common location is around the joints of the wrist where it appears as a firm, fluctuant, pea-sized, translucent nodule. It arises as a result of cystic or myxoid degeneration of connective tissue; hence the cyst wall lacks a true cell...
Pathology
null
432064ad-b9e3-4f0e-8dc8-663a6b43f4a4
Epidemiological Web of Causation theory was given by
Louis Pasteur
Robe Koch
McMahon and Pugh
None
2c
multi
The 'web of causation' considers all the predisposing factors of any type and their complex interrelationship with each other. Ref: 25th edition, Park's Textbook of Preventive and Social Medicine, Page no. 41
Social & Preventive Medicine
Concept of health and disease
6c899ce7-3619-4446-abd4-0c6c12be59a0
A 57 year old male suffering from acute pancreatitis develops sudden onset breathlessness with a CVP< 18mmHg. The chest xray shows bilateral infiltrates. The possible diagnosis is -
ARDS
Myocardial infarction
Congestive left heart failure
Pulmonary embolism
0a
single
Ans. is 'a' i.e., ARDS ARDS Criteria 1. Acute, meaning onset over 1 week or less. 2. Bilateral opacities consistent with pulmonary edema must be present and may be detected on CT or chest radiograph. 3. PF ratio < 300 mmHg with a minimum of 5 cmH20 PEEP (or CPAP). 4. C VP < 18 mmHg. X-Ray showing bilateral infiltrates:
Surgery
Pathophysiology - Acute Pancreatitis
e94dab85-5794-49e7-b65f-39ede69cfc00
Intravenous immunoglobulin is given in-a) Kawasaki diseaseb) GB syndromec) Heart blockd) Atrial fibrillatione) Myasthenia gravis
abc
bcd
abe
acd
2c
single
null
Medicine
null
4c6e43c0-1894-4858-b91c-0f78d0c5f813
Action potential is produce by
Sodium Influx
Sodium Efflux
Potassium Influx
Potassium Efflux
0a
single
(A) Sodium Influx # Action potential is due to opening of Na+ channels causing "Na+ influx"> As the membrane potential is increased, sodium ion channels open, allowing the entry of sodium ions into the cell. This is followed by the opening of potassium ion channels that permit the exit of potassium ions from the cell.>...
Physiology
Misc.
8fdeb7e5-7c73-4279-ab22-5602ed57dcf9
Fat provides ____________ of body's calories
40%
30%
50%
75%
1b
single
null
Biochemistry
null
07f46f52-8802-4fc0-a9d5-4ace3646b0fb
Therapeutic drug monitoring is required for: March 2010
Sulfonamides
Metformin
Cycloserine
Gentamycin
3d
single
Ans. D: Gentamycin
Pharmacology
null