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135
cab538a9-e414-4761-abf5-4217342c10b5
Hydrogen peroxide is conveed to water and oxygen by enzyme?
Superoxide dismutase
Catalase
Glutathione peroxidase
Myeloperoxidase
1b
single
Catalase, present in peroxisomes, catalyzes the decomposition of hydrogen peroxide (2H2O2 - O2 + 2H2O). Glutathione (GSH) peroxidases are a family of enzymes whose major function is to protect cells from oxidative damage 2 GSH (glutathione) + H2O2 - GS-SG + 2 H2O. myeloperoxidase conves H2O2 to a highly reactive compou...
Pathology
General pathology
9410aae9-11d1-4fe5-83f9-fa8c7c681748
Hypercalciuria is seen in:
Hyperparathyroidism
Vit. D intoxication
Sarcoidosis
All
3d
multi
Answer is D (All of the above): Hypercakiuria may be associated with Vitamin D intoxication (hypervitaminosis D), Sarcoidosis and hyperparathyroidism. Causes of Hypercalciuria-associated Nephrolithiasis in Children and Adults Idiopathic hypercalciuria Increased intestinal calcium absorption - Granulomatous disease e.g....
Medicine
null
ce0b6354-cb8e-49d0-8237-2f4d0a9c6015
Schneider's Ist rank symptoms seen in:
Delusion
Hallusination
Schizoid personality
Schizophrenia
3d
multi
D i.e. Schizophrenia
Psychiatry
null
0be19b6a-f3e5-400c-b5f2-9b0f8d2d3c52
Killian's dehiscence is seen in -
Oropharynx
Nasopharynx
Cricopharynx
Vocal cords
2c
single
Between these two parts of inferior constrictor exists a potential gap called Killian's dehiscence. It is also called the gateway to tear as perforation can occur at this site during esophagoscopy. It is also the site for herniation of pharyngeal mucosa in case of the pharyngeal pouch.
ENT
null
7c88db32-7fdf-45fc-b9c3-f81928343ea1
Hypsarrythmia in a child is due to-
Grandmal epilepsy
Petitmal epilepsy
Myoclonic epilepsy
Reflex epilepsy
2c
single
Ans. is 'c' i.e., Myoclonic epilepsy Myoclonic epilepsy may be ? i) Infantile spasm or Infantile myoclonus or west syndrome ii) Juvenile myoclonic epilepsy Infantile spasm (Infantile myoclonus or west syndrome) o The onset is usually between 3-8 months of life o It is characterized by triad of ? i) Salaam spells (sudde...
Pediatrics
null
7a084eda-8cc4-45c1-817e-acc5617f9d82
All of the following are adverse effects of thalidomide except :
Myocarditis
Constipation
Peripheral neuropathy
Sedation
0a
multi
Thalidomide was banned because of teratogenic effects (phocomelia). Now it has come again in the market for use as an anticancer drug in multiple myeloma and melanoma. Lenalidomide is its more potent and non-teratogenic derivative. Thalidomide most commonly causes sedation and constipation in cancer patients. It can al...
Pharmacology
null
36294498-f87b-4308-b954-4b6a865525c0
Neurotoxin is which snake -
Viper
Krait
Sea snake
None
1b
multi
Ans. is 'b' i.e., Krait Type of poisoningSnakeVasculotoxicVipersMyotoxicSea snakesNeurotoxicElapids- cobra, Krait, coral
Forensic Medicine
Forensic Toxicology - Concepts, Statutes, Evidence, and Techniques
0ec5e0bb-fe80-46fe-9df1-97717d9e15b2
Single gene defect causing multiple unrelated problems is called?
Pleiotropism
Pseudodominance
Penetrance
Anticipation
0a
multi
Pleotropism refers to single gene defect causing multiple traits. Penetrance- extent to which a paicular gene or set of genes is expressed in the phenotypes of individuals carrying it Pseudodominance- sudden appearance of a recessive phenotype in a pedigree, due to deletion of a masking dominant gene Anticipation- dise...
Pediatrics
Types of Genetic Disorders
5589428e-2bcc-4236-98de-17f5aa5834b8
Urinary bacterial count of 105 is insignificant, in the absence of symptoms, in all of the following conditions except -
Pregnancy
Healthy ambulatory male
In a setting of antibiotics treatment
Mid stream clean catch sample.
0a
multi
Significant growth of a Uropathogen in the absence of symptoms is termed Asymptomatic bacteriuria. Urinary bacterial count of 105 is significant in Pregnancy. Pathogens associated with UTI most commonly in pregnancy are most commonly E coli, along with Klebsiella, proteus, enterobacter, staphylococcus saprophyticus. Si...
Gynaecology & Obstetrics
Medical Illness Complicating Pregnancy
a0728f6c-8d2b-4823-9959-788773e6dd66
Elastomers are
Alginate
Agar
Polyethers
Impression compound
2c
single
According to Chemistry Chemically, there are four kinds of elastomers: Polysulfide Condensation polymerizing silicones Addition polymerizing silicones Polyether
Dental
null
202d763e-20b8-40ce-b440-5fbc875c8df6
Cotton fever is due to the abuse of:
Amphetamine
Heroin
Phencylidine
Cocaine
1b
single
COTTON FEVER : Fever developing due to injection of a water extract of the cotton remaining after the heroin supply is used in a "bag"
Forensic Medicine
Drug Abuse
49638ada-64a9-4d6d-b321-37f211f7fdc9
What causes both destruction of bone and reduction of joint space?
Tuberculosis
Metastasis
Multiple myeloma
Lymphoma
0a
multi
(a)TB in spine involves- 2 Vertebra (Bone) + Disk (Cartilage)- Paradiscal- Anterior (to spinal cord)Note: Involvement of posterior elements and single vertebra is relatively rare in TB.
Orthopaedics
TB of the Spine
3291e548-1e25-4fd4-9ae5-4405781ba419
The commonest malignant tumour of the lids is
Basal-cell carcinoma
Squamous cell carcinoma
Adenocarcinoma
Melanocarcinoma
0a
single
MALIGNANT TUMOURS Basal-cell carcinoma It is the commonest malignant tumour of the lids (90%) usually seen in elderly people. It is locally malignant and involves most commonly lower lid (50%) followed by medial canthus (25%), upper lid (10-15%) and outer canthus (5-10%). Clinical features: It may present in four forms...
Ophthalmology
Tumors
91a52612-02f4-416e-af79-76a08ba16695
How much fraction of methyl mercury is absorbed from the Gut:
20%
50%
80%
100%
3d
single
null
Dental
null
09961acd-c3fa-44e2-9e40-fa13b40dae37
Point B in the treatment of carcinoma cervix receives the following dose of:
7000 cGy
6000 cGy
5000 cGy
10,000 cGy
1b
single
Two important points in the radiotherapy of cancer cervix are
Gynaecology & Obstetrics
null
2f7e3f25-db30-4e3a-adf6-526642bfcf93
A 40-year old alcoholic develops cough and fever. Chest X-ray show an air-fluid level in the superior segment of the right lower lobe. The most likely etiologic agent is:
Strept. pneumoniae
H influenzae
Legionella
Anaerobes
3d
single
Ans. D. AnaerobesOf the organisms listed, only anaerobic infection is likely to cause a necrotizing process Type III pneumococci have been reported to cause cavitary disease, but this is unusual. The location of the infiltrate suggests aspiration, also making anaerobic infection most likely. The superior segment of the...
Medicine
Respiratory
9ab58cad-4387-4ce8-bfcd-e19fb7062653
Myoclonus in children is best treated by :
Clonazepam
Sodium Valproate
Phenobarbitone
Ethosuximide
1b
single
null
Pharmacology
null
dd42a7b8-a020-4c0d-bf74-17392546c167
The antidote of poisoning due to Arninanita muscaria is
Physostigmine
Amyl nitrate
Methylene blue
Atropine
3d
single
D i.e. Atropine Amanita muscaria & Amanita phalloides are poisonous mushrooms with parasympathetic (Cholinergic) symptoms. So AtropineQ is used as antidote in severe cases; but avoided in mild case as it excerhates delirium.
Forensic Medicine
null
24e48cdd-1a16-43a2-89d6-66667d91560d
Baonella quintana causes:
Trench fever
Scrub typhus
Endemic typhus
Epidemic typhus
0a
single
Ans. is. 'a' i. e., Trench fever
Microbiology
null
1a05c417-521e-4555-a3b3-d530796ff92f
The main poion of the ovarian aery, vein, and nerves are carried to and from the ovary by way of the:
Suspensory ligament
Ovarian ligament
Broad ligament
Mesovarium
0a
single
The suspensory ligament attaches the ovary to the pelvic wall and carries within its folds the main poion of the ovarian vessels and nerves. The ovarian ligament attaches the inferior pole of the ovary to the uterus. The broad ligament is a double-fold of parietal peritoneum, which hangs over the uterus (mesentery of t...
Gynaecology & Obstetrics
null
5a6b5e0b-abe0-4732-9d20-249597090085
Barr body is absent in -
Kleinfelter
Turner
Super female
None of the above
1b
multi
Ans. is 'b' i. e., Turner Barr body (Sex- chromatin)o It is a densely staining inactivated condensed 'X' chromosome that is present in each somatic cells of female,o It is found in the nucleus.o It is used as a test of genetic femaleness - it is possible to determine the genetic sex of an individual according as to whe...
Pathology
Mendelian Disorders: Single-Gene Defects
bfc972c1-0a3a-49eb-8140-7241c54be57d
Which of the following is most likely to produce a junctional scotoma
Meningioma
Craniopharyngioma
Pituitary gland enlargement
All the above
0a
multi
Junctional scotoma is due to lesion at junction of Optic nerve and chiasma. Which is m/c due to meningioma.
Ophthalmology
null
b0e0db62-2e78-4597-8d7b-66b7fcc63104
Perversion with pain to self: TN 09; Maharashtra 11
Transvestism
Fetishism
Sadism
Masochism
3d
single
Ans. Masochism
Forensic Medicine
null
1ae6c6bd-de83-42d5-8235-025d5fa422b4
Which of the following H1 blocker has high anticholinergic activity :
Cetirizine
Chlorpheniramine
Fexofenadine
Astemizole
1b
single
null
Pharmacology
null
70cd8e61-97f0-490f-989a-2bc4e93fad26
In acute inflammation endothelial retraction leads to
Delayed transient increase in permeability
Immediate transient increase in permeability
Delayed prolonged increase in permeability
Immediate transient decrease in permeability
2c
single
ref Robbins 8/e p45,9/ep74 Several mechanisms may contribute to increased vascu- lar permeability in acute inflammatory reactions: * Endothelial cell contraction leading to intercellular gaps in postcapillary venules is the most common cause of increased vascular permeability. Endothelial cell con- traction occurs rapi...
Anatomy
General anatomy
2c4d5f8b-666c-47a2-a4ab-470b1a5d3abb
Aery of anatomical snuffbox?
Radial
Ulnar
Brachial
None
0a
multi
Ans. is 'a' i.e., RadialAnatomical Snuffbox Triangular depression on the dorsal and radial aspect of the hand become visible when thumb is fully extended. BoundariesMedial/Posterior--Tendon of the extensor pollicis longus.Lateral/Anterior--Tendon of the extensor pollicis brevis and abductor pollicis longus.Roof--Skin a...
Anatomy
null
5b0287fc-7e96-444f-9686-c9ea4407b98a
Cysticercosis cellulosae causes infection with
Taenia saginata
Echinococcus granulosus
Taenia solium
Diphyllobothrium latum
2c
multi
null
Social & Preventive Medicine
null
1134f8c2-ebad-4c42-bb4a-2d198b87a947
Which of the following can be given orally?
Cytosine arabinoside
Cisplatin
Doxorubicin
Mesna
3d
multi
MESNA ,is a drug used to reduce the undesired side effects of ceain chemotherapy drugs. It is referred to as a "chemoprotectant." and prophylactic agent used to reduce the incidence of ifosfamide-induced hemorrhagic cystitis. How this drug is given: As an injection or infusion through the vein (intravenous, IV). This i...
Pharmacology
Chemotherapy
b246096e-4220-4df4-a8e3-2104b1f05017
This cream is appropriate for all of the following procedures Except
Venipuncture
Laceration repair
Lumbar puncture
Myringotomy
1b
multi
EMLA (eutectic mixture of local anesthetics) is a eutectic mixture of 5 percent lidocaine and prilocaine that is used to produce anesthesia over intact skin. Its primary use is to produce anesthesia before venipuncture and lumbar puncture. In other settings, this cream has been used for anesthesia of split-thickness gr...
Anaesthesia
Anaesthesia of special situations
5ee69c94-23d1-4c09-95cb-cd003d6c1915
Not a fungal infection is:
Mycoses fungoides
Tinea nigra Palmaris
White Piedra
Black Piedra
0a
single
Ans: A (Mycoses fungoides) Ref: Rook's Dermatology, 8th ed.Explanation:Mycosis Fungoides/Sezary SyndromeMycosis fungoides and Sezary syndrome are different manifestations of a tumor of CD4+ helper T cellsClinically, the cutaneous lesions of mycosis fungoides typically progress through three somewhat distinct stages, an...
Skin
Cutaneous Manifestations of Microvascular Occlusion Syndromes
1caf84a6-5879-4f54-94a8-beceb5c57192
Antisocial personality is seen with :
Drug abuse
Paranoid schizophrenia
OCN
None
0a
multi
A i.e. Drug abuse
Psychiatry
null
4f47cb53-574e-4ba6-a56f-499dc7f94b7d
All are viral causes of PUO except:
EBV
CMV
HIV
Leptospirosis
3d
multi
Ans: d (Leptospirosis) Ref: Harrison, 16 ed, p. 116, 17th ed, p. 132A quite straight forward question. The answer is leptospirosis because it is not a viral cause of PUOPUO: (Pyrexia of unknown origin)Definition:Temperature >38.3(IC on several occasionsOrA duration of fever of >3 weeksOrFailure to reach a diagnosis des...
Medicine
Infection
0059bce5-2cb2-4b4e-9c08-ab9e4063db97
In disaster management following are practiced except
Triage
Rehabilitation
Mass vaccination
Disaster response
2c
multi
Disaster Management includes three aspects: 1. Disaster impact and response: Search, rescue, and first-aid * Field care * Triage * Tagging * Identification of the dead 2. Rehabilitation or recovery: * Water supply * Basic sanitation and personal hygiene * Food safety * Vector control 3. Mitigation: Measures designed ei...
Social & Preventive Medicine
All India exam
cc7536ef-7adc-4b0f-8e6f-80d224434292
A patient having cystic medial necrosis with necrotising aeritis is suffering from?
Kawasaki disease
Temporal aeritis
Malignant hypeension
Aooaeritis
3d
single
Cystic medial degeneration . Smooth muscle loss . Fibrosis . Inadequate ECM synthesis . Accumulation of increasing amounts of amorphous proteoglycans Robbins 9 th edition page no. 345
Pathology
Cardiovascular system
20a427f7-68e2-40d6-b47c-71638d46f617
A 27 year old female having a family history of autoimmune disease presents with the complaints of a skin rash and recurrent joint pains 3 months after delivering a baby. She is most likely to have which of the following disorders?
Megakaryocytic thrombocytopenia
Amegakaryocytic thrombocytopenia
Functional platelet defect
Acquired Factor VIII inhibitors
3d
single
Acquired factor VIII deficiency Muscle and soft tissue bleeds are common. Bleeding into a joint results in severe pain and swelling, as well as loss of function, but is rarely associated with discoloration from bruising around the joint. Life-threatening sites of bleeding include bleeding into the oropharynx, where ble...
Pathology
Clotting factor
6e0e399d-5e3d-4f98-9740-4bc8c330e280
Commonest cause of cataract
Hereditary
DM
Trauma
Age related
3d
single
D i.e. Age related Radiation cataract is caused by exposure to almost all types of radiation energy such as infrared or heat (in glass-blowers or glass-workers, and iron-workers), irradiation caused by X-rays, gamma-rays or neutrons (in workers in atomic energy plant, survivors of atomic bomb and in patients inadequate...
Ophthalmology
null
61910706-6994-442b-a8ad-5c9af8e48434
All are metabolic causes of liver disease except
Histiocytosis
Hemochromatosis
Gaucher's disease
Wilson disease
0a
multi
Ans. is 'a' i.e., HistiocytosisMetabolic liver diseases can be classified into 3 categories:Manifestations due to hepatocellular necrosis: Galactosemia, hereditary fructose intolerance, tyrosinemia type I, Wilson disease, Hemochromatosis and al -antitrypsin deficiency.Cholestatic jaundice :Al -antitrypsin deficiency, B...
Pediatrics
null
b8534a3d-42b8-410e-be54-d0e66188f199
Not be cultured in Sabouraund's agar -
Blastomyces
Coccidiodes
Sporotrichum
Rhinosporidium seeberi
3d
single
null
Microbiology
null
98a9b606-7f47-470a-a6b1-a59baa8622ac
The most common type of intussusception?
Ileocolic
Colocolic
Ileoileal
Retrograde
0a
single
Ans. a (Ileocolic) (Ref. Bailey and Love 26th/pg. 114).ACUTE INTUSSUSCEPTION# Telescoping/invagination of one portion of the gut within an immediately adjacent segment; invariably it is the proximal into distal bowel. An intussusception is composed of three parts: the entering or inner tube; the returning or middle tub...
Surgery
Small & Large Intestine
995ce7c7-5fa1-4397-af58-d8561d45e7ed
Holdswoh classification of thoracolumbar spine fracture is based on how many columns of spine?
Two
Three
Five
Four
0a
single
Answer- A. TwoHoldswoh,s proposed two column concept of thoracolumbar spine fractureAntetior column : Consists veebral body, annulus fibrous, Anterior and posterior longitudinal ligamentsposterior column: Consists of veebral arch (pedicle, facets, laminae) and posterior ligaments (ligamentum flavum,interspinous and sup...
Surgery
null
32c401bd-69c1-4840-99af-b0f4bef76ee4
Chvostek’s sign is elicited by
BP cuff in arm for 5 minutes
Facial nerve stimulation by tapping over the parotid
Tapping over extensor pollicis brevis
Tapping over flexor retinaculum
1b
single
The Clinical manifestations of hypocalcemia are mostly due to neuromuscular irritability.  The patients complains of paresthesias which are typically perioral or of the hands and feets  Tetany is the classic manifestation of hypocalcemia, the manifestations are :  Corpopedal Spasm o Laryngospasm o Seizures Latent tetan...
Medicine
null
829a468f-da8d-4b0a-aec0-0e9bbd44dde4
All of the following may be used to differentiate Central Retinal Venous Occlusion (CRVO) from ocular Ischemic syndrome due to carotid artery stenosis, Except –
Dilated retinal vein
Tortuous retinal vein
Retinal artery pressure
Opthalmodynamometry
0a
multi
Dilated retinal vein is seen both in CRVO and ocular ischemic syndrome; therefore, this feature cannot differentiate these two. However, in CRVO vein is tortuous while in ocular ischemic syndrome it is non-tortuous. Retinal artery perfusion pressure is decreased in ocular ischemic syndrome and is normal in CRVO. Ophtha...
Ophthalmology
null
da95e43a-b779-4d66-bada-9edf88ad9aa9
The commonest clinical pattern of basal cell carcinoma is -
Nodular
Morpheaform
Superficial
Keratotic
0a
single
• Locally invasive carcinoma, arises from the basal layer of the epidermis • MC type of skin cancer • 90% of BCC are seen in the face, above a line from the corner of mouth to lobule of ear. • MC site: Nose >Inner canthus of the eye, also known as Tear cancer. Types of BCC • Nodular: MC type of BCC, characterized by sm...
Surgery
null
0e8ec33a-593f-40cb-a207-43f4fe18510c
The origin of ovaries from
Genital ridge
Genital tubercle
Wolffian duct
Miillerian duct
0a
single
null
Anatomy
null
a3a998b8-6ea2-4f20-beaa-84d95b3e96ef
Hyperprolactinemia is a side effect of
Bromocriptine
Levodopa
Amantadine
Metoclopramide
3d
single
null
Pharmacology
null
9fa5976f-240c-4a6c-9d73-d14cc43a568a
Rose-waaler test is
Precipitation test
Passive agglutination test
Neutralisation test
Complement fixation test
1b
single
It is rapid slide haemagglutination test for detection of rheumatoid factor.
Microbiology
null
5825017b-3e3b-4e56-977d-47ce1216df9b
Medical treatment of ectopic pregnancy is :
Methotrexate
Progesterone
Oestrogen
Adriamycin
0a
single
Methotrexate
Gynaecology & Obstetrics
null
038ba0fb-a130-4b12-8a5d-ce94b4248b91
A class C diabetic patient delivers at term, it is impoant to check her blood sugar levels immediately postpaum, since there may be a decrease in the insulin requirements of diabetic patients. This can be paly explained by :
Increased food intake
Decreased activity
Decrease in plasma chorionic somatomammotropin
All
2c
multi
Decrease in plasma chorionic somatomammotropin
Gynaecology & Obstetrics
null
b510bf91-1870-4708-99a9-d364f0a6bc62
True about third hea sound is-
Present in constrictive pericariditis
Absent in aoic aneurysm
Absent in MS
Present in cardiac yamponade
2c
multi
The third hea sound (S 3 ) occurs during the rapid filling phaseof ventricular diastole. It can be a normal finding in children,adolescents, and young adults; however, in older patients it signifieshea failure. A left-sided S 3 is a low-pitched sound best heard overthe left ventricular (LV) apex. A right-sided S 3 is u...
Medicine
C.V.S
d97f1637-3e43-4e6a-8033-ce8a68eb825c
Large way vegetation are characteristic of?
SLE
SABE
Both
None
1b
multi
Ans. is 'b' i.e., SABE
Pathology
null
8a0445e3-11dc-4ee7-b806-6d5b35049c2c
Not a content of sphenopalatine fossa
Maxillary Artery
Maxillary nerve
Mandibular nerve
Pterygopalatina ganglion
2c
single
null
ENT
null
618a69ab-d802-45bc-98ea-324ac099d365
Anomalies of oral cavity most commonly found in which stage
Embryonic
Period Of Fertilization
Period Of Fetus
None
0a
multi
null
Anatomy
null
7567d44d-bd7e-41bb-9ca2-2b829a708499
Drug of choice for treatment of intermediate uveitis is
Cycloplegics
Analgesics
Steroids
Antibiotics
2c
single
Treatment for Intermediate uveitis : Intravitreal or Posterior Subtenon's Steroid injections : Triamcinolone acetonide Steroids may also be given by subconjuntival route or by Subtenon's route
Ophthalmology
Uveitis
fb4c385b-0147-48f5-ac78-0f26bd4b61f3
Primary bile acid is?
Deoxycholic acid
Lithocholic acid
Chenodeoxycholic acid
None
2c
multi
Ans. is 'c' i.e., Chenodeoxycholic acid Primary bile acids are cholic acid and chenodeoxycholic acid, which are synthesized from cholesterol in liver. In the intestine some of the primary bile acids are conveed into secondary bile acids, i.e., deoxycholic acid (formed from cholic acid) and lithocholic acid (derived fro...
Biochemistry
null
b07345f2-9d5f-477b-a264-b7d7f7db91eb
Which β1 selective blocker is used in glaucoma:
Levobunolol
Timolol
Betaxolol
Carteolol
2c
single
null
Pharmacology
null
4aa1e149-e761-4715-9c8a-5a35e526dc94
What diagnosis is suggested by these spirography findings?
Intrathoracic localized obstruction
Fixed inspiratory obstruction
Pneumothorax
Restrictive lung disease
0a
single
Answer A. Intrathoracic localized obstructionAn intrathoracic localized obstruction is demonstrated on spirography. The patient underwent flexible fiberoptic bronchoscopy, which revealed nearly complete (greater than 90%) occlusion of the distal trachea by a vascular mass. The patient recovered after endoscopic laser a...
Medicine
Respiratory
b55306cf-4ae2-4f8b-a1ee-b597615514d8
Which is a yeast like fungi: September 2007
Cryptococcus
Candida
Blastomyces
Histoplasma
1b
single
Ans. B: Candida Yeast like fungi grow paly as yeast and paly as elongated cells resembling hyphae.The latter form a pseudomycelium. Candida albicans is a pathogenic yeast-like fungus.
Microbiology
null
562e1720-f55d-403f-a600-255b950bb93a
Which one of the following variants of renal cell carcinoma has the worst prognosis -
Papillary
Tubuloalveolar
Chromophobe
Sarcomatoid
3d
single
null
Pathology
null
811346e2-3002-4b26-ade9-b659f52e623c
Observation of yeast cells with multiple budding in tissue in the form of a “the shape shown in below pictomyograph ” is highly suggestive of
Blastomycosis
Cccidiodomycosis
Paracoccidiodomycosis
Histoplasmosis
2c
single
Paracoccidioides brasiliensis causes paracoccidioido­mycosis. It is a dimorphic fungus that exists as a mold in soil and as a yeast in tissue. The yeast is thick­walled with multiple buds ("ship's wheel" appearance), in contrast to Blastomyces dermatitides, which has a yeast with a single bud that has a broad base. His...
Unknown
null
94b50a87-26ea-4bce-8ec0-088e46c13a4d
Which of the following is the most significant component of a behavioral program developed to help a mother deal with a child having oppositional defiant disorder?
Positive reinforcement
Punishment
School suspension
Strict parenting
0a
single
Positive reinforcement of promoting desirable behaviours through rewards is the most significant component of the program used to deal with ODD.
Psychiatry
Miscellaneous
c3486349-0243-4b8a-9e17-abb9922727a4
Most common cause of leukocoria in newborn is
Congenital cataract
Toxocara infection
Retinoblastoma
CMV infection
0a
single
.
Pathology
All India exam
4a33573c-4661-4d05-a657-45aa6f9e51b5
Which of the following is the site of bladder injury in abdominal hysterectomy is :
Anterior wall
Posterior wall
Medial wall
Lateral wall
1b
multi
Posterior wall
Gynaecology & Obstetrics
null
cdb4b387-9e3b-4390-9a71-9c58907c021c
Paul -Bunnell test is positive in:
Infectious mononucleosis
Multiple myeloma
Malignant nerves
Rubella
0a
single
null
Pathology
null
f20b01a9-bab5-4b41-b7d4-da0af2cac1b2
A 10 year old child with aggressive, self mutilating behavior and poor concentration is brought with presenting complaints of joint pain and reduced urinary output. Child's presentation is most likely due to the deficiency of which enzyme?
HGPase
Adenosine Deaminase
APase
Acid Maltase
0a
single
The child in the question stem is showing features of Lesch nyhan syndrome caused by deficiency of HGPase. Hypoxanthine guanine phosphoribosyl transferase is an enzyme responsible for the formation of hypoxanthine to inosoic acid and guanine to guanylic acid. This enzyme deficiency can present in a complete form only i...
Biochemistry
null
371ac31c-1a40-4504-9606-186ebb9e2820
A 56 year old man has been having bloody bowel movements on and off for the past several weeks. He repos that the blood is bright red, it coats the outside of the stools, and he can see it in the toilet bowl even before he wipes himself. When he does so, there is also blood on the toilet paper. After fuher questioning,...
Anal fissure
Cancer of the cecum
Cancer of the rectum
External hemorrhoids
2c
single
The combination of red blood coating the stools and a change in bowel habit and stool caliber spells out cancer of the rectum in someone in this age group. Anal fissure is typically seen in young women who have very painful bowel movements with streaks of blood. Pain is the dominant symptom in this condition. Cancer of...
Surgery
null
256c20ed-28b5-49fb-bab2-f18541d823b9
What is the best procedure to control external hemorrhage in an event of accidental injury?
Elevation
Direct pressure
Proximal tourniquet
Aery forceps
1b
single
Direct firm pressure applied over the bleeding area or the involved aery at a site that is proximal to the wound is the best way to control external hemorrhage. A firm pressure dressing is applied and the injured pa is elevated to stop venous and capillary bleeding if possible. If the injured area is an extremity it sh...
Surgery
null
6f92701a-991d-4d3e-b0e1-a2a48d58561a
5day baby full term breast fed with bilirubin 14mg Idl weight is 2700g what should be done next ?
Normal newborn care
Phototherapy
Exchange transfusion
stop breastfeeding
0a
single
Age Min TSB to sta phototherapy 24hrs > 10mg 1dL 48hrs >13mg 1dL 72hrs >15mg1dL 96hrs and beyond >18mg1dL Reference: GHAI Essential pediatrics, 8th edition
Pediatrics
All India exam
7f12afe4-5e5b-4860-821c-7bfe352f1b82
The paradoxical response of GH release to TRH is seen in -
Prolactinoma
Acromegaly
Malnutrition
Pitutary adenoma
1b
single
TRH stimulates the secretion of prolactin as well as TSH, Normally it does not affect growth hormone secretion but in acromegaly TRH induced growth hormonal stimulation Occurs. Note: "In prolactinomas paradoxical response of TRH to prolactin occurs". In normal individuals, TRH stimulates prolactin release Where as in...
Medicine
null
402b0151-25ba-4a21-b37d-aa0a617eefc4
How many mm from the limbus is the safest site of intravitreal injection?
1-2 mm
2-3 mm
3-4 mm
4-5 mm
2c
single
(Refer: AK Khurana Comprehensive Ophthalmology, 6th edition, pg no. 171)Intravitreal injection (distance from Limbus)For aphakics-3mmFor pseudophakes-3.5mmFor phakics-4mm
Ophthalmology
Vitreous and retina
c328b3cf-abec-4fca-8b6d-ee1efb422f0f
Which one of the following cofactors must be utilized during the conversion of acetyl-CoA to malonyel-CoA?
Thiamine pyrophosphate
Acyl carrier protein (ACP)
Biotin
FAD
3d
single
FAD The key enzymatic step of fatty acid syn thesis is the carboxylation of acetyl-CoA to form malonyl-CoA. The carboxyl of biotin is covalently attached to an E-amino acid group of a lysine residue of acetyl-CoA carboxylase. The reaction occurs in two stages. In the first step, a carboxybiotin is formed: HCO3- + bioti...
Surgery
null
df7c4ca4-713e-406b-9d1f-d815f807ecb4
Which of the following is not consider to be a slow viruse diseases -
Kuru
Scrapie
Creutzfeldt Jakob disease
Sarcoidosis
3d
single
kuru,scrapie,&CJD Are caused by slow virus REF:ANATHANARAYANAN MICROBIOLOGY NINTH EDITION PAGE.557
Microbiology
Virology
097951d4-f171-453c-9c7e-c054e07ddbc1
Sleepwalking occur in which stage of sleep -
REM
NREM stage
NREM stage 3 or 4
Can occur in any stage of NREM sleep
2c
single
Sleep walking (somnambulism) is seen in stage 3 & 4 of NREM sleep.
Psychiatry
null
49d94986-c502-4c57-aa8e-5602085c54d0
Which one of the following device provides fixed performance oxygen therapy:
Nasal Cannula
Venturi mask
O2 by T-piece
SO2
1b
single
B i.e. Ventimask Ventimask or venturimasks are high flow or fixed performance (performance not affected by changes in patient's tidal volume and respiratory rate) oxygen delivery devicesQ delivering accurate oxygen concentration
Anaesthesia
null
67e09240-1f5c-4cd2-9d28-f441dfd21194
House Brackmann scale is for which nerve?
Facial nerve
Trigeminal
Optic
Hypoglossal
0a
single
null
Anatomy
null
0a977f95-6357-4e8b-9f6f-3001e5b705d7
Nerve supply of tip of nose
Ext nasal branch of ophthalmic division of
Inferior orbital nerve
Buccal br of mandibular nerve
Orbital of maxillary n
0a
single
Nerve supply General sensory nerves derived from the branches of trigeminal nerve are distributed to whole of the lateral wall: Anterosuperior quadrant is supplied by the anterior ethmoidal nerve branch of ophthalmic nerve. Anteroinferior quadrant is suplied by the anterior superior alveolar nerve branch of infraorbita...
Anatomy
Head and neck
3d127567-efb0-4f20-8070-f54310ba8805
The scoring given in periodontal index for gingivitis is
1
2
4
6
1b
single
null
Dental
null
44e3850e-92ca-43cb-b1e1-108c82d8547a
Features of carcinoma penis include all except: March 2007
Metastasize to inguinal lymph nodes
Surgery is the treatment of choice
Hypospadias is a premalignant lesion
Circumcision provides protection
2c
multi
Ans. C: Hypospadias is a premalignant lesion Following as risk factors for penile cancer: Human papillomavirus (HPV) infection, smoking, smegma, phimosis, treatment of psoriasis, age, and AIDS. The other etiologic factor most commonly associated with penile carcinoma is poor hygiene. Lichen sclerosus (also known as bal...
Surgery
null
9b67ab79-55ec-4005-91e0-9874ad934308
A 60-year-old male, chronic smoker, presented with fatigue and chest pain. On examination, there was inset left eyeball with drooping upper left eyelid and reduced left pupil size. Which of the following is the most likely diagnosis in this condition?
Squamous cell carcinoma involving the apex of his left lung
Adenocarcinoma involving left mainstem bronchus
A small-cell carcinoma involving the hilum of his left lung
Bronchioloalveolar carcinoma involving the left lower lobe
0a
multi
Most tumors of the apex of the lung are adenocarcinomas Pancoast tumors - apical lung tumors in the superior pulmonary sulcus tend to invade the neural structures around the trachea, including the cervical sympathetic plexus. Involvement of sympathetic fibers gives rise to severe pain in the distribution of the ulnar n...
Pathology
Lung Tumor
3edf72da-42f9-4a59-a539-5acb552acee6
A patient died during surgery. The relatives allege that death was due to negligence. According to a recent Supreme Cou judgment, doctor can be charged for Medical Negligence under section 304-A, only if:
There is corporate negligence
Negligence is from inadveent error
There is gross negligence
It falls under the doctrine of Res Ipsa Loquitor
2c
multi
Ans. c. There is gross negligence A physician can be charged with criminal negligence in Section 304 A, when a patient dies from the effects of anesthesia during, an operation or other kind of treatment, if it can be proved that the death was the result if malicious intention, or gross negligence. "Section 304-A deals ...
Forensic Medicine
null
6d74cea1-1536-4127-b0a0-89e46e0e9f6e
Localization in insulinoma is best with -
Contrast computerized tomography
Margnetic resonance imaging
Somatostatin receptor scintigraphy
Selective angiography
3d
single
The insulinoma might be localized by noninvasive means, using ultrasound, CT scan, or MRI techniques. An indium-111 pentetreotide scan is more sensitive than ultrasound, CT, or MRI for detection of somatostatin receptor positive tumors, but not a good diagnostic tool for insulinomas. An endoscopic ultrasound has a sens...
Medicine
G.I.T
f6fc2cdc-f9bc-475f-ab6b-06ed3a54f8c1
The nerve mediating pain of External hemorrhoids is:
Hypogastric nerve
Inferior rectal nerve
Pelvic splanchnic nerve
Sympathetic plexus
1b
single
-External hemorrhoids --> present below pectinate line , painful bleeding is present --> pain carried by Inferior Rectal Nerve (branch of pudendal nerve). -Internal haemorrhoids --> present above pectinate line --> painless bleeding is its feature.
Anatomy
Development of GU system and Neuro-vascular supply of pelvis & perineum
f17ffc1c-1ad4-438a-8724-0bb55b7195d7
Myelin sheath in the central nervous system is formed by
Schwann cell
Microglia
Oligodendrocytes
Protoplasmic astrocytes
2c
single
Oligodendrocytes are responsible for myelination in the CNS. In the PNS, Schwann cells form the myelin sheath. The process of myelination begins before bih and is not complete until a year or more after bih. (Ref: Vishram Singh textbook of neuroanatomy, second edition, pg- 19)
Anatomy
Brain
0d832879-8f04-473f-af74-ae46860e8fa6
Female presents with history of color change from pallor to cyanosis on exposure to cold in fingers. This condition is mostly associated with?
Scleroderma
Leukemia
Lung infections
Hepatosplenomegaly
0a
multi
A. i.e. Scleroderma Raynaud's phenomenon (i.e. cold/vibration/emotional stress-exposure Vt pallor --> cynosis & finally erythemaQ of digits, ear & tip of nose) is almost always present (along with skin sclerosis) and is often earliest featureQ of Systemic sclerosis (Scleroderm). It may precede extensive skin & internal...
Skin
null
164419b8-dd0f-4900-9a87-f38317065cfc
ESR is raised in -a) Sickle cell anaemiab) Multiple myelomac) Acute myocardial Infarctiond) Angina pectoris
bc
c
ac
ad
0a
single
null
Pathology
null
33574c5a-e7eb-442c-a8b5-80ea49f72d80
True statements are all except:
Chromosome six has the genes for MHC
Genes encoding complement proteins are located adjacent to class I
Monocytes have MHC II antigens on their surface
Class III does not encode complement
3d
multi
1.) The gene encoding for MHC molecules are clustered on small segment of chromosome 6. 2.) MHC II molecules are present on all the APC's (Antigen Presenting Cells), and Monocyte are type of Antigen Presenting cell. 3.) Class III is present adjacent to Class I and Class II. 4.) Class III encodes for complement protein.
Pathology
Basic Concepts
e88e60fe-09bf-4f33-8b38-3f6c0982ba42
Hypothyroidism is caused by which of the following anti-tubercular drug -
PAS
Ethionamide
Cycloserine
Pyrazinamide
0a
single
Ans. is 'a' i.e., PAS Adverse effects of para-amino salicylic acid (PAS) --> Anorexia, nausea, epigastric pain, rashes, goiter (hypothyroidism), fever, malaise, liver dysfunction, and blood dyscrasias. Adverse effects of ethionamide :Anorexia, nausea, vomiting, abdominal pain, hepatitis, optic or peripheral neuritis, m...
Pharmacology
null
22a75ef6-3a84-496a-8c23-0f623ce5a54b
During growth cycle of a child, usually at what age childhood ends and adolescence stas?
8 years
10 years
12 years
16 years
1b
multi
WHO/UN definitions: Adolescent - 10-19 years Youth - 15-24 years Young people - 10-24 years Ref: Ghai essential pediatrics, 6th edition, Page 66.
Pediatrics
null
3439cfa2-5c40-4469-88ec-273f678a7ad4
Which of the following can lead to infiltration of ear lobules, loss of nails and resorption of distal phalanges?
Tuberculoid leprosy
Lepromatous leprosy
Indeterminate leprosy
Any of the above
1b
multi
Ans. B. Lepromatous leprosy. (Ref. Harrison's 18th/pg. 1362)LEPROSYSpecific symptoms vary depending on the type of leprosy.# Tuberculoid leprosy: A rash appears, consisting of one or a few flat, whitish areas. Areas affected by this rash are numb because the bacteria damage the underlying nerves.# Lepromatous leprosy: ...
Skin
Bacterial Infection of Skin
6c52fdac-3892-4594-a82d-247b9d316d66
One of the following molecules acts as a mobile electron carrier in the respiratory chain
Ubiquinone
FADH2
FeS
Cytochrome b
3d
multi
Ref: Harper&;s Biochemistry; 30th edition; Chapter 13; The Respiratory Chain & Oxidative Phosphorylation
Biochemistry
Metabolism of carbohydrate
e80ec545-20db-4083-ba0b-382109d991fb
Symptom of hypoglyemia is -
Sweating
Bradycardia
Chest pain
Breathlessness
0a
single
Ref - Davidsons 23e p739
Medicine
Miscellaneous
cecfbe5e-53ac-4425-ace0-b9e6888ec441
True about DNA structure
Purines are adenine and guanine & pyrimidines are uracil and cytosine
Waston and Crick discovered structure in 1973
Deoxyribose - phosphate backbone with bases stacked inside
Mainly consists of left handed helix
2c
multi
Deoxyribonucleic acid (DNA) stores information for the synthesis of specific proteins. DNA has deoxyribose as its sugar. DNA consists of a phosphate group, a sugar, and a nitrogenous base. The structure of DNA is a helical, double-stranded macromolecule with bases projecting into the interior of the molecule. These two...
Biochemistry
Metabolism of nucleic acids
458f0a76-b21f-4abc-976a-f387e0e73052
A 36-year-old female presents with heavy menstrual bleeding. She has one child of 7 years. USG shows a single 3x3 cm submucosal fibroid. Hemoglobin is 10.5 gm/dl. What is the best treatment option for her?
GnRH injection
UAE
Hysteroscopic myomectomy
Laparoscopic myomectomy
2c
multi
Ans. is c, i.e. Hysteroscopic myomectomyThis patient is having heavy menstrual bleeding due to fibroid, i.e. she is symptomatic and hence management has to be done. Best management in fibroid is surgery. Since she is only 36 years and has one child We will go for myomectomy.Submucous fibroid <5cm, should be removed hys...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
5b09c31d-4f53-42f8-8815-8e43eb017ea5
All of the following are true about dermatitis herpetiformis except:
Severe itchy skin lesions over extensor surfaces
Most of the patients have underlying coeliac disease
It is characterized by IgE anitbodies against TTG : Tissue transglutaminase
Dapsone is the drug of choice
2c
multi
IgA antibodies are seen against TTG.
Dental
null
8f33fa27-fc5d-40c7-a7cd-5aaeb247ad89
Delta bilirubin is ______ bilirubin _____ bound to albumin.
Conjugated, covalently
Unconjugated, non-covalently
Conjugated, noncovalently
Unconjugated, covalently
0a
single
Delta bilirubin or biliprotein is the fraction of conjugated bilirubin that is covalently bound to albumin. This is responsible for the lab finding of persistent hyperbilirubinemia even after the disappearance of jaundice in cases of obstructive jaundice. -Chromatographic fractionation of serum bilirubin: a bilirubin u...
Biochemistry
HAEM synth and porphyrias
85f404c9-ac8f-432b-89a6-7d9d5cbf54f5
Cushing syndrome as paraneoplastic syndrome is seen with all malignancies, EXCEPT:
Bronchial carcinoid
Thymus
Medullary carcinoma thyroid
Papillary carcinoma thyroid
3d
multi
Paraneoplastic Syndrome Ectopic Hormone Typical Tumor Hypercalcemia of malignancy Parathyroid hormone-related protein Squamous cell (head and neck, lung, skin), breast, genitourinary, gastrointestinal 1,25 dihydroxyvitamin D Lymphomas Parathyroid hormone Lung, ovary Prostaglandin E2 (PGE2) Renal, lung Syndrome of inapp...
Medicine
null
fb8cc7bf-df8e-4d84-8ed6-3b7918c8c751
Prevention of emergence of risk factor is -
Primordial prevention
Primary prevention
Secondary prevention
Tertiary prevention
0a
single
It is the prevention of the emergence or development of risk factors in countries or population groups in which they have not yet appeared.
Social & Preventive Medicine
null
48ee40bb-0929-4af3-aaaa-53b1d688fe7e
Blalock and Taussig shunt is done between -
Aoa to pulmonary aery
Aoa to pulmonary vein
Subclan aery to pulmonary vein
Subclan vein to aery
0a
single
Ans. is 'a' i.e., Aoa to Pulmonary Aery Blalock Taussig shunt consists of subclan aery (br. of aoa) and pulmonary aery anastamosis. This inturn actually establishes a shunt between the aoa (Via the subclan aery) and the pulmonary aery. Management of T.O.F. Medical Management Limited to management of complications and c...
Pediatrics
null
29aaa99a-67f9-4f0b-ba26-e99403633ff9
Accessory meningeal artery enters cranial cavity through:
Foramen lacerum
Foramen rotundum
Foramen spinosum
Foramen ovale
3d
single
Accessory meningeal artery is a branch of 1st part of Maxillary artery.  It enters the cranium by passing through foramen ovale. It supplies meninges and infratemporal fossa.
Anatomy
null
f86fa460-08ce-4eb9-a873-109617f9fcfa
The following statements about thyroglossal cyst are true, except
Frequent cause of anterior midline neck masses in the first decade of life
The cyst is located within 2 cm of the midline
Incision and drainage is the treatment of choice
The swelling moves upwards on protrusion of tongue
2c
multi
Thyroglossal cysts are the most common cause of midline neck masses. Can occur anywhere along the path of the thyroglossal duct, from the base of the tongue to the suprasternal notch (in the midline) Treatment must include excision of the whole thyroglossal tract, which involves removal of the body of the hyoid bone an...
Surgery
Endocrinology and breast
dc139ed4-36b5-49c0-988e-088b2cde7441
A 10 year old child develops hematuria after 2 days of diarhoea. Blood film shows fragmented RBCs. Which of the following is likely diagnosis-
Acute pyelonephritis
Disseminated intravascular coagulopathy
Haemolytic uremic syndrome
Haemolytic crises
2c
single
null
Medicine
null