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135
8e2418de-2bd0-4503-af33-09d70f425dbb
Serum does not contain
Fibrinogen
Cerruloplasmin
Albumin
Globulin
0a
single
Serum has essentially the same composition as plasma, except that its fibrinogen and clotting factors II, V, and VIII (Table 32-5). (Ref: Ganong's review of medical physiology 23rd Edition page no.530)
Physiology
General physiology
98576ce6-8bdf-4cd2-b11a-75cd9e229c95
Renal threshold for glucose is:
80 mg%
100 mg%
180 mg/dl
200 mg%
2c
single
null
Biochemistry
null
62d1f728-d1cd-427c-a26a-294f077a7d7b
Forbe&;s disease is due to deficiency of
Branching enzyme
Debranching enzyme
Myophosphorylase
Hepatic phosphorylase
1b
single
Glycogen storage disease type III is an autosomal recessive metabolic disorder and inborn error of metabolism characterized by a deficiency in glycogen debranching enzymes. It is also known as Cori&;s disease in honor of the 1947 Nobel laureates Carl Cori and Gey Cori. Other names include Forbes disease in honor of cli...
Biochemistry
Metabolism of carbohydrate
46aababe-a4f0-44f6-8414-54f25ecd02bf
Adult worm of Echinococcus is found in:
Dog
Humans
Domestic animals
Felines
0a
single
Ref. Textbook of Microbiology and Immunology BY Parija. – Compiled from Various chapters
Unknown
null
e1a96b9c-2fa4-49c7-8f4f-9e831669aac2
All of the following are except- advantages of LMA
More reliable than face mask
Prevent aspiration
Alternative to Endotracheal intubation
Does not require laryngoscop & Visualization
1b
multi
LMA is also called Brain mask .It is a supraglottic airway device.It is intermediate between face mask and ETT. Used in difficult airway,in minor and day care surgeries,no muscle relaxant is necessary Disadvantage is it doesn&;t prevent aspiration of gastric contents.
Anaesthesia
Anaesthetic equipments
61292294-d7c9-4914-87b7-56b94d7dc3ff
In herpes simplex encephalitis, drugs used are, EXCEPT:
Acyclovir
Vidarabine
Ganciclovir
Amantadine
3d
multi
The most effective drug for herpes simplex encephalitis is acyclovir, given intravenously at a dosage of 10 to 15 mg/kg every 8 hours, with each dose given over 1 hour. Ganciclovir is an analogue of acyclovir which is active against all herpes viruses including Herpes simplex. Vidarabine is a purine nucleoside analogue...
Pharmacology
null
e5e1da36-d58e-452c-b7de-afa63fd3cfe4
NOT a hypolipidemic drug:
Simvastatin
Fenofibrate
Somatostatin
Fluvastatin
2c
single
Ans. (c) SomatostatinRef. KDT 6th ed. / 235SOMATOSTATIN* Somatostatin inhibits the secretion of GH, TSH and prolactin by pituitary, insulin and glucagon by pancreas and most importantly. It inhibits most of G.I secretions gastrin and HC1.* It can be used in controlling esophageal varices and bleeding peptic ulcer.* Dru...
Pharmacology
Hypolipidemic Drugs
7e01f270-13e8-4449-847f-436e6aada581
Factors that produce acute pancreatitis include all of the following except
Alcohol
Hypercalcemia of parathyroid origin
Gall stones
Haemochromatosis
3d
multi
The two leading causes associated with acute pancreatitis are alcoholism and cholelithiasis, both of which are implicated in more than 80% of cases. Less common causes of acute pancreatitis include trauma, ischaemia, shock, extension of inflammation from the adjacent tissues, bloodborne bacterial infection, viral infec...
Pathology
G.I.T
2262a9d2-e7d3-4b36-8c1f-4f88195621da
Carbenicillin:
Is effective in pseudomonas infection
Has no effect in Proteus infection
Is a macrolide antibiotic
Is administered orally
0a
multi
Ans. (A) Is effective in pseudomonas infection(Ref: KDT 8/e p773)Carbenicillin is a penicillin congener effective against pseudomonas and indole positive proteus which are not inhibited by penicillin G or ampicillin/amoxicillin.It is inactive orally and excreted rapidly in urine. It is sensitive to penicillinase and ac...
Pharmacology
Chemotherapy: General Principles
5bd0e750-f5ff-4ecd-af21-2dff2a65f597
Topical immunomodulator used for the treatment of genital was is:
Imiquimod
Podophylline
Interferon
Acyclovir
0a
single
Genital wa treatments that can be applied directly to your skin include: Imiquimod (Aldara, Zyclara). This cream appears to boost the immune system's ability to fight genital was. Avoid sexual contact while the cream is on your skin. It may weaken condoms and diaphragms and may irritate. One possible side effect is red...
Pharmacology
Immunomodulators
09c102f2-0d33-4ee1-9bcf-dfc45d044430
Within an hour after cementation of cast gold onlay patient complains of shooting pain every time the teeth comes together. Most probable explanation is?
Supraocclusion of restoration
Retained cement in gingival sulcus
Excess acid in mix
Galvanic current caused by gold onlay occluding with a large restoration
3d
single
null
Dental
null
2ff1eb62-ce35-411e-9d71-5dc69aad8b21
All are true regarding staphylococcal toxin except ?
Beta haemolysin shows hot cold phenomenon
Mainly endotoxin
Enterotoxin causes food poisoning
Exfoliative toxin causes Reiter's syndrome
1b
multi
Ans. is 'b' i.e., Mainly endotoxin Impoant facts about virulence factors . Clumping factor is bound coagulase which is responsible for the slide coagulase test. . Coagulase (free coagulase) - Acts along with a coagulase reacting factor (CRF) in plasma. - Eight type of coagulase have been identified, most human strains ...
Microbiology
null
2fb42f16-a50e-4397-9ec6-049048876ec1
Staph. aureus causes vomiting in 2 hours after eating contaminated milk product . The mechanism of action is -
Stimulation of C AMP
Vagal stimulation
Stimulation of C GMP
Acts through ganglioside GM receptor
1b
single
Option 1, 3 Increase in cyclic AMP/GMP-accumulation of sodium chloride in the intestinal lumen- Diarrhea. Option 2 Toxin Stimulates the vagus nerve and vomiting center of brain. Acts directly on the autonomic nervous system rather than on gastrointestinal mucosa. Option 4 Cholera toxin: binds to GM1 ganglioside recepto...
Microbiology
Systemic Bacteriology Pa 1 (Gram Positive Cocci, Gram Negative Cocci)
ba98b1a1-3e43-41be-aa72-41120c5be8c4
A patient presents with Hb of 8 gm% , WBC count of 2000/mm3 and platlet count of 60000/mm3. What is your likely diagnosis?
Thalassemia
Sickle cell anemia
Aplastic anemia
Anemia of chronic disease
2c
single
ANSWER: (C) Aplastic anemiaREF: Harrison's 18th ed Ch: 107It's a straight forward diagnosis of Aplastic anemia since all the three cell lines of blood are reduced. The very basic question tests your knowledge of normal blood counts
Medicine
Anemia and RBC Disorders
7a7ef69c-8103-43ae-a688-3c7c1ccdbec7
Holt-Oram syndrome is characterized by?
ASD
VSD
TGA
TAPVC
0a
single
Holt-Oram syndrome: - Autosomal dominant disorder - Characterized by - skeletal abnormalities of hands and arms like: Hypoplastic/ absent thumbs, radii Triphalangism Phocomelia - Cardiac anomalies ASD 1st degree hea block TRIPHALANGISM phacomelia
Pediatrics
Acyanotic congenital hea diseases
896ee284-f6c0-41a6-ade7-05928f20cc8a
Branch of facial nerve in facial canal
Greater petrosal nerve
Nerve to Stapedius
Chordatympani
All
3d
multi
A. i.e. Greater petrosal nerve; C. i.e. Chorda tympani; B . i.e. N. to stapedius
Anatomy
null
91d81f2b-fc53-4505-86ac-71ea64cb45f5
Ca Vulvaof the anterior pa will spread primarily to which of the following lymph nodes?
Para-aoic
Inguinal
Obturator
Femoral
1b
single
Vulval Lymphatics: Superficial component - drains the anterior two-thirdvulva, to the superficial inguinal lymph nodes Deep drainage system - draining the posterior one-third vulva is to deep inguinal nodes, external iliac, and femoral nodes In Ca Vulva the lymphatic spread is usually to the inguinal lymph nodes, which...
Gynaecology & Obstetrics
Vulvar cancer
04794897-0e4a-4a72-948a-7952ff0f530b
Protein di sulphide isomerase is involved in
Protein synthesis
Protein degradation
Protein folding
Protein quaernary structure formation
2c
single
Disulfide bonds between and within polypeptides stabilize teiary and quaternary structures. However, disulfide bond formation is nonspecific. Under oxidizing conditions, a given cysteine can form a disulfide bond with the --SH of any accessible cysteinyl residue. By catalyzing disulfide exchange, the rupture of an S--S...
Biochemistry
All India exam
16ba4f3b-af21-49a9-b30c-b2aacd7908b7
Most common precipitating factor for COPD is
Environment
Smoking
Allergen
All of the above
1b
multi
null
Medicine
null
c4763d38-5b86-4e73-b9e3-5e5f5d6dca15
The differential diagnosis for pancytopenia with cellular bone marrow include the following except -
Megaloblastic anemia
Myelodysplasia
Paroxysmal Nocturnal Hemoglobinuria
Congenital dyserythropoietic anemia
3d
multi
null
Pathology
null
0ac4ba5d-a465-474d-9390-f737a6985e03
Facial nerve palsy can be caused by -
Cholesteatoma
Multiple sclerosis
Mastoidectomy
All of the above
3d
multi
Ans. is 'd' i.e., Ail of the above Causes of facial paralysis1. Central :-Brain abscess, pontine glioma, Polio, multiple sclerosis2. Intracranial part (cerebellopontine angle) :- Acoustic neuroma, meningioma, congenital cholesteatoma, metastatic carcinoma, meningitis3. Intratemporal part:-Idiopathic :- Bell's palsy, Me...
ENT
Facial Nerve And Its Disorders
38331f46-3c4f-4774-babc-326b0f94e5f6
Which is the thinnest pa of the lens of eye?
Anterior pole
Posterior pole
Posterior capsule
Apex
1b
single
The lens is thinnest at the posterior pole. The crystalline lens is surrounded by a lens capsule. Lens capsule is a thin transparent elastic membrane secreted by the lens epithelial cells largely composed of type IV collagen. The capsule is 11- 15microm thick at the anterior pole. The posterior capsule thickness decrea...
Ophthalmology
null
731db598-d6ee-4bbb-96aa-3612303eba60
A 60 year old man presented with watering from his left eye since 1 year. Syringing revealed a patent drainage system. Rest of the ocular examination was normal. A provisional diagnosis of lacrimal pump failure was made. Confirmations of the diagnosis would be by:
Dacryoscintigraphy
Dacryocystography
Pressure syringing
Canaliculus irrigation test
0a
single
Ans. Dacryoscintigraphy
Ophthalmology
null
2536caec-babe-4897-96bf-0053ab46a3dd
The type of mammary ductal carcinoma in situ (DCIS) most likely to result in a palpable abnormality in the breast is -
Apocrine DCIS
Neuroendocrine DCIS
Well differentiated DCIS
Comedo DCIS
3d
single
Carcinoma of the breast is divided into : Carcinoma in situ → neoplastic cells is limited to ducts and lobules by the basement membrane. Invasive carcinoma (infiltrating carcinoma) → cells invade beyond the basement membrane. Caricnoma in situ : It is of two types A. Ductal carcinoma insitu (DCIS, intraductal carin...
Pathology
null
ef0a1fa5-9ee8-4cec-9812-f9418d614c4a
Not a complication of gallstone
Mucocele
Diveiculosis
Acute cholangitis
Empyema of the gallbladder
1b
multi
Effects and complications of Gallstones In gallbladder In Bile duct In Intestine Silent stones Acute cholecystitis Chronic cholecystitis Mucocele Empyema Perforation Gangrene Carcinoma Obstructive jaundice Cholangitis Acute pancreatitis Gallstone ileus Ref: Sabiston 20th edition Pgno : 1492-1493
Surgery
G.I.T
bff7f88b-36a1-456b-ac3b-8ade6ff2ff2b
Ujjwala is for -
Child abuse
Child trafficking
Child labour
None
1b
multi
Ujjawala ,a comprehensive scheme to combact trafficking was launched in infia by the Ministry of Women and Child Development.REF.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE.Editon-21.Page no.-542
Social & Preventive Medicine
obstetrics,pediatrics and geriatrics
ed9bae02-c6f4-4303-8d21-856c8d03ef6d
Which of the following drug is useful in the prophylaxis of meningococcal meningitis?
Minocycline
Doxycycline
Cephalexin
Rifabutin
0a
single
Minocycline is used in acne and for prophylaxis of meningococcal meningitis.Ref: HL Sharma 3rd ed Pg:
Pharmacology
Antibiotics
cb0f755c-b8a8-4d9e-8622-6e902e36580b
A 40 year old female patient presents with excessive bleeding. Patient gives a history of road traffic accident 5 hours ago and had a lacerated wound on lower back region. Blood grouping test reveals presence of Anti A antibody, Anti B antibody, Anti H antibody and Anti Rh D antibody in the serum. The blood group of th...
O positive
O negative
AB positive
Bombay blood group
3d
single
→ Apart from A< B and O RBC of type O contains large amount of another antigen called H substance. → H substance is genetically different from ABO but is a precursor of A and B antigens. → An O group individual who inherits A or B genes but fails to inherit H gene from either parent is called Oh phenotype or Bombay blo...
Pathology
null
32f4e671-7e97-4184-8eb5-e1c3e961e5ab
IOC for Bronchiectasis -
HRCT scan
Spiral CT
Bronchoscopy
Pulmonary angiography
0a
single
The best test to evaluate the destruction and dilatation of large airways which are filled with pus in Bronchiectasis is HRCT. Spiral CT is preferred for pulmonary embolism. Pulmonary angiography is done for lung sequestration and is gold standard for pulmonary embolism.
Medicine
null
08d59913-c169-4e0c-9345-6a29cd31ed5b
All of the following are neurologic channelopathies except -
Hypokalemic periodic paralysis
Episodic ataxias
Familial hemiplegic migraine
Huntington's disease
3d
multi
null
Medicine
null
4c875ee2-97cf-493e-9383-6258d5d1289a
M/C ovarian cancer associated with endometriosis:
Endometroid tumor
Clear cell tumor
Germ cell tumor
Brenner tumor
1b
single
Ans. is b, i.e. Clear cell tumorM/C ovarian cancer associated with endometrial cancer: Endometrioid tumorM/C ovarian cancer associated with endometriosis: Clear cell carcinoma
Gynaecology & Obstetrics
Carcinoma Ovary
9aa4c73a-b90c-417f-a526-2bf5c83eae9a
The only Sugar normaly absorbed in the intestine against a concentration gradient is :
Xylose
Mannose
Glucose
Ribose
2c
single
C i.e. GlucoseFinal products of carbohydrate digestion in intestinal chyme are glucose & fructoseQ.The glucose transpo in intestine is an example of secondary active transpo i.e., the energy of glucose transpo is provided indirectly by active transpo of Na+ out of cell. Because glucose & Na+ share the same cotranspoer ...
Physiology
null
0301e367-c3b0-450c-b514-24f163f4b979
A young patient with a headache, epiphora, bilateral nasal obstruction but no fever. Diagnosis is
Nasal polyp
Juvenile angiofibroma
Nasal carcinoma
Rhinoscleroma
1b
single
CLINICAL FEATURES 1. Age and sex. Tumour is seen almost exclusively in males in the age group of 10-20 years. Rarely, it may be seen in older people and females. 2. Profuse, recurrent and spontaneous epistaxis. This is the most common presentation. The patient may be markedly anaemic due to repeated blood loss. 3. Prog...
ENT
Pharynx
d74815e4-8d9a-49b0-8ac2-28e10234a3fc
What is the recommended illumination for general office work?
100 lux
400 lux
900 lux
1000 lux
1b
single
The recommended illumination for casual reading is 100 lux, 400 lux for office work, 900 lux for fine assembly and for watch making 2000 - 3000 lux is recommended. Ref: Park's Textbook of Preventive Medicine, 17th Edition, Page 519.
Social & Preventive Medicine
null
1c3ab0ae-6ef9-4dad-b40f-25ff49e4e1c3
All reduce lactation except - a) Maternal anxiety b) Retracted nipple c) Dehydration d) Diabetes e) Antibiotics
abc
abd
cde
ace
2c
multi
null
Medicine
null
63bdea0f-f89c-457f-a161-f7b799b7ff27
Lucio phenomenon is treated with:
Steroids
Lenalidomide
Clofazimine
Exchange transfusion
3d
single
Lucio phenomenon seen in leprosy- recurrent crops of large, sharply marginated, ulcerative lesions paicularly on the lower extremities. These are frequently fatal as a result of secondary infection and consequent septic bacteremia. Neither glucocoicoids nor thalidomide is effective against this syndrome. Optimal wound ...
Medicine
Bacterial infection
e565c892-f20a-40bc-b108-6b6036a918bf
Complications of prematurity are all except
Intra - ventricular hemorrhage
Necrotising enterocolitis
Retinitis Pigmentosa
Periventricular leukomalacia
2c
multi
Retinopathy of prematurity is complication of prematurity.
Gynaecology & Obstetrics
null
f3d17073-af2e-4f37-87a4-430946237c93
WHO definition of normal sperm count:
10 million/ml
20 million/ml
40 million/ml
50 million/ml
1b
single
Normal sperm count/ml i.e. sperm concentration is 20 million/ml.
Gynaecology & Obstetrics
null
314d5db0-1f09-4876-961e-e33886281986
Center of rotation for tipping is present at:
Long axis of tooth
Between B-L axis of tooth
Between M-D axis of tooth
Infinity
0a
single
Uncontrolled tipping: A single force is applied at the crown, whereby the tooth rotates around a point just apical to the CRes. The crown moves in the direction of the force and the apex of the root moves in the opposite direction. The CRes of the tooth also moves in the direction of the force. Controlled tipping: Exam...
Dental
null
acd83d6a-dd8a-4b4c-a1bb-61a0b328ce51
Relative polycythemia are caused by all of the following, EXCEPT:
Dehydration
High altitude
Gaisbock syndrome
Dengue haemorrhagic fever
1b
multi
High altitude is associated with physiological increase in erythropoietin levels resulting in secondary polycythemia and not relative polycythemia. Polycythemia refers to increase in RBCs, WBCs, and platelets, but in common practice is used to describe increased red cells or erythrocytosis. It can be primary, secondary...
Medicine
null
d107e6c0-0169-44c8-9ce5-371bfd6eff9e
Body fluids are classified under which catogory of waste
Humanized waste
Infectious waste
Pathological waste
Anatomical waste
2c
single
null
Social & Preventive Medicine
null
fd33410b-c36a-4d9b-93e1-cc03ac0f5e9f
Physical quality of life index is measured by all, Except
Infant moality
Life expectancy at age one
Literacy
Per capita income
3d
multi
(Refer: K. Park's Textbook of Preventive and Social Medicine, 24th edition, pg no: no: 17, 18)Human Development Index (HDI) Vs Physical Quality of Life Index (PQLI)HDIPQLIComponentsLongevity - Life expectancy at bih (LEdeg/LEdeg)Income (Real GDP per capita in PPP US$)Knowledge (Mean years of schooling - Gross enrolment...
Pathology
All India exam
f4bddd19-d69b-4a97-aad6-f3488e8a0863
All are synonymous to radial styloid fracture except
Chauffer's fracture
Hutchinson fracture
Backfire fracture
March fracture
3d
multi
null
Orthopaedics
null
e4f8c2d8-44f1-41c7-8728-e23673e67a80
Which of the following doesn't occur during the processing of RNA?
Terminal addition
Nucleoside modification
Nucleoside cleavage
Chemical hydrolysis
3d
single
Precursor tRNA is processed to form mature tRNA. Alterations during processing are of three types: nucloelytic reactions, nucleoside modifications, terminal additions of nucleotides. Chemical hydrolysis is not a pa of RNA processing. Poly A tailing and 5'capping occurs in the processing of RNA. Methylation and deaminat...
Biochemistry
null
27e1bf61-14b8-427b-be90-14b1c9ff3a0f
Which cranial nerve supplies lateral rectus muscle?
Trochlear
Trigeminal
Abducens
Glossopharyngeal
2c
single
Ans. C Abducens* All the extraocular muscles are supplied by CN III except lateral rectus and superior oblique.* Lateral rectus supplied by--CN VI* Superior oblique supplied by--CN IVRemember- LR6;SO4
Anatomy
Neuroanatomy
aeb834d8-c8b4-47bc-944c-17281e690401
Treatment of recently sputum positive case of pulmonary TB is
RMP + INH + PZM
RMP + INH + PZM + SMC
RMP + INH + PZM + ETM
RMP + INH + ETM
2c
single
Ans. c (RMP + INH + PZM + ETM); (Ref. Park PSM 22nd/pg. 175)Treatment categories and sputum examination schedule in DOTS chemotherapy in IndiaTREATMENT REGIMENSPUTUM EXAMINATIONS FOR PULMONARY TBCategory of treatmentType of patientRegimenPret- reat- ment sputumTest at monthIF: result is-----THEN:New cases Category I Re...
Social & Preventive Medicine
Communicable Diseases
3f1ff750-0365-41e7-98b7-a4c67fecc49e
RBC cast in the microscopic examination of the urine is an indicator of -
Acute glomerulonephritis
Acute Pyelonephritis
Chronic glomerulonephritis
Nephrotic syndrome
0a
single
null
Medicine
null
990457bf-05eb-4c82-ba2e-015421f746a9
In a 27 yr old male most common cause of a colo-vesical fistula would be:
Crohns disease
Ulcerative colitis
TB
Cancer colon
0a
single
Diveicular disease is the most common cause of colovesical fistula, followed by colon cancer and Crohn disease. Diveicular disease and colon cancer are rare in people younger than 40 years. Here this patient is young; hence the most suitable answer is Crohn's disease. Ref: ACP Medicine: Volume 1, 2007, Page 816.
Surgery
null
5676c39c-f60b-4ccd-9509-91428fa7df61
Number of structural gene in Lac operon
3
4
5
6
0a
single
Lactose operone or Lac operon The lac operon is a region of DNA in the genome of E. coli that contains following genetic elements ? i) Three structural genes :- These code for 3 proteins that are involved in catabolism of lactose. These genes are 'Z' gene (codes for P-galactosidase), 'Y' gene (codes for galactoside per...
Biochemistry
null
b9e8bc7b-1521-43d6-9890-de7ac80d81c0
Chondroblastoma most commonly occurs in :
Metaphysis
Diaphysis
Epiphysis
Medullary cavity
2c
single
Ans. is 'c' ie Epiphysis Apley's orthopedics writes - "Chondroblastoma is one of the few lesion to appear primarily in the epiphysis"
Orthopaedics
Bone Tumour
5e40f87b-3d60-45ab-b5dd-63e7df7e6b98
Laudanosine is metabolic end product of
Mivacurium
Doxacurium
Rocuronium
Atracurium
3d
single
Laudanosine is metabolic end product of atracurium.
Anaesthesia
null
63ffc17d-d422-4f81-83b1-45171b0b15d5
Cephalic index 75- 80 is seen in
Indians
Europeans
Chinese
Mongolians
0a
single
Cephalic index 1.Dolicocephalic ( long headed) 70-75 2.Mesaticephalic(medium headed) 75- 80 3. Brachycephalic( sho headed) 80-85 Present study aimed at working outcephalic index in Indian students. 100 students were taken as subjects and head length, head breadth were measured. Indian males had meancephalic index of 77...
Forensic Medicine
Identification
dd0738df-d0e0-4223-ba68-3d8a03ccf6ea
Airway noise originating in the nose, nasopharynx and oropharynx is known as:
Stridor
Steor
Both of the above
None of the above
1b
multi
Stridor is a harsh noise produced by turbulent airflow through a paially obstructed airway. It may be inspiratory, expiratory, or both (biphasic). The term steor is used to describe airway noise originating in the nose, nasopharynx, and oropharynx; therefore, stridor is generally of laryngeal or tracheal origin.
ENT
null
285006de-c1e2-4c96-82a2-4b18a47099ab
Hot flushes are experienced as a result of
Increased noradrenaline
Decreased estrogen
Increased noradrenaline and decreased estrogen
Increased noradrenaline and estrogen
2c
single
Hot flushes are caused by noradrenaline, which disturbs the thermoregulatory system. Oestrogen deficiency reduces hypothalamic endorphins, which release more norepinephrine and serotonin. This leads to inappropriate heat loss mechanism. Other causes that can be associated with the symptom of hot flushes include: thyroi...
Gynaecology & Obstetrics
All India exam
0e6612f9-8a65-457b-ab0e-9ce5f39ad9fd
In Alzheimer's disease (AD) which of the following is not seen:
Aphasia
Acalculia
Agnosia
Apraxia
1b
single
B i.e. Acalculia
Psychiatry
null
42810ff2-829a-48ad-9b3d-934c658b0fbb
Parietal cells in the stomach secrete a protein crucial for the absorp on of vitamin B12 by the ileum. What is this protein?
Intrinsic factor
Gastrin
Somatostatin
Cholecystokinin (CCK)
0a
single
.
Pathology
All India exam
1ece3df0-5b5c-4487-8bb2-a23c02bff7c4
How many parathyroid glands do humans have?
4
3
2
1
0a
single
Parathyroid glands: The parathyroid glands are small, yellowish-brown, ovoid or lentiform structures, usually lies between the posterior lobar borders of the thyroid gland and its capsule. They are commonly 6 mm long, 3-4 mm across, and 1-2 mm from back to front, each weighing about 50 mg. Usually, there are two on eac...
Anatomy
null
9252bbd0-9b65-49d6-958f-9e2f9d50573b
A 45-year-old man is worried about a dark pigmented skin lesion on his arm. The "mole" is 3 mm wide, symmetric with a regular border and even pigmentation. He reports no change in size or other symptoms. Which of the following is the most appropriate next step in management?
observation only
excisional biopsy
punch biopsy
chemotherapy, then surgical excision
0a
multi
(a) Source: (Kasper, pp. 500-502) Observation alone is adequate for this lesion. The "ABCD" rules are helpful in distinguishing benign skin lesions from malignant melanoma. (A) asymmetry, benign lesions are symmetric; (B) border irregular, most nevi have clear-cut borders; (C) color variation, benign lesions have unifo...
Medicine
Oncology
7817419f-7c0e-46a7-8fbe-1e89b3a0715f
Unconjugated hyperbilirubinemia-
85% of the total should be indirect
Hemolytic anemia
Haemoglobin destruction ( bilirubin production)
50% of the total should be indirect
0a
single
Normal adults contain less than 1mg/dL of total bilirubin out of which less than 0.25 mg/dL is conjugated bilirubin. Unconjugated bilirubin is estimated by substracting direct bilirubin value (Harsh mohan page 593)
Medicine
G.I.T
f2700e1f-7df6-4e1d-8686-cb5682f200eb
An epidemiological investigation undertaken to test the hypothesis regarding the causation of a disease is called
Case control study
Cohort study
Prospective study
Descriptive study
0a
multi
null
Dental
null
c3dd9e0b-0333-4c4a-b8af-b9b462ad44ca
Diagnostic procedure for basal cell Ca -
Wedge biopsy
Shave
Incisional biopsy
Punch biopsy
0a
single
null
Surgery
null
86e44022-63ad-4250-9143-0c6e86294712
All are first generation cephalosporins except :
Cefadroxil
Cefazolin
Cephalexin
Cefaclor
3d
multi
null
Pharmacology
null
dd2268c4-5974-4a4c-8b2f-3869edc505e8
Uveoparotitis is seen in -
SLE
Sjogren's syndrome
Rheumatoid arthritis
Sarcoidosis
3d
single
null
Medicine
null
958cd7de-be16-4c0f-ade7-5c86c6ba1dba
25 years old gentleman has repeated thoughts that he has not locked his car door properly and frequently checks it while driving. He also repeatedly checks locks in his house. Diagnosis is
OCD
OPCD
Phobia
Somatoform disorder
0a
single
Obsessive compulsive disorder (OCD) and obsessive compulsive personality disorders a(OCPD)two different types of disorders OCD is classified under anxiety disorders whereas OCPD is classified under personality disorder Patients with OCD have recurrent, irresistible, irrelevant and intrusive thoughts that are EGO DYSTON...
Psychiatry
Personality disorders
724fd086-7e4a-42d6-b1ae-1817185e9183
Most common false neurological sign is:
Wasting of hands
Abnormal unilateral pupil
Diplopia
Unilateral papilledema
2c
multi
Diplopia REF: Journal of Neurology, Neurosurgery Psychiatry 2003; 74:415-418 Doi:10.1136/ jnnp.74.4.415, Neurological signs have been described as "false localizing" if they reflect dysfunction distant or remote from the expected anatomical locus of pathology. False localizing signs occur in two major contexts: as a co...
Surgery
null
c0a70046-2318-497a-911c-c4a76b0ea390
Umami taste is evoked by
Glucose
Glutamic acid
Quinine
Sodium chloride
1b
single
Glutamic acid is responsible for umami taste Ref: guyton and hall textbook of medical physiology 12 edition page number: 713,714,715
Physiology
Nervous system
9fa903e6-ea89-4f2c-8c69-a718eff2ae49
The following anti T.B. drug should not be given to AIDS patient-
The following anti T.B. drug should not be given to AIDS patient-
Ethambutol
Streptomycin
Pyrazinamide
0a
single
Ans. is 'a' i.e., Rifampicin
Pharmacology
null
c86b146c-2c6e-496b-8184-8cf8947cfffa
Banding technique most commonly employed for cytogenetic analysis
G banding
C banding
R banding
Q banding
0a
single
G-banding (most common) R-banding Q-banding C-banding T-banding G stands for Giemsa R stands for "reverse" Q stands for Quinacrine Fluoroescent dye C stands for Constitutive heterochromatin or Centromere T stands for telomeres to produce a visible karyotype Dark regions are heterochromatin (AT) Light regions are Euchro...
Biochemistry
Techniques in molecular biology
d9cb3fd8-834c-43b2-b467-f2408ec00646
In a CA lung patient is suffering from dyspnoea, the palliation of dyspnoea is achieved by
Morphine patch
Diazepam
Clobazam
Haloperidol
0a
multi
Morphine is used for dyspnea in terminally ill cancer patients by : Both endogenous (b-endorphin) and exogenous (morphine) opioids modulate the perception of dyspnea by binding to opioid receptors. Proposed mechanisms whereby opioids relieve refractory dyspnea include decreasing respiratory drive with an associated dec...
Pharmacology
Respiratory system
8b654d0e-f4ff-40af-8e1d-eeea9c891834
True about Moorens ulcer: March 2007, March 2013
Painless condition
Affects cornea
Sudden loss of vision
Bilateral in majority of cases
1b
multi
Ans. B: Affects cornea Mooren's ulcer is a rare, painful, inflammatory condition affecting one or both eyes that results in the destruction of corneal tissue. The cause of Mooren's ulcer is unknown. It is generally agreed that it is an autoimmune condition. Pain is almost always associated with the onset of Mooren's ul...
Ophthalmology
null
c6299767-f0cf-46c7-bec3-30d5958c2067
Thanatology deals with
Death in all aspects
Postmortum findings
Exhumation
Body of offence
0a
multi
Ans) a (Death in all aspects) Ref.KNS Reddy 20th ed p 122Thanatology deals with death in all aspects.There is a progression from clinical death to brain death, biological death, biological death and then cellular death. Brain death follows immediately clinical death due to lack of oxygen. First the cerebral cortex, the...
Forensic Medicine
Death and Medicolegal Aspects
a48a1276-5de9-4402-9927-45621949cdcc
Spontaneous CSF leak associated with all except
Increased intracranial tension
Paial or complete empty sella syndrome
Pseudotumour cerebri
Low risk encephalocoele
0a
multi
spontaneous cerebrospinal fluid leak (SCSFL) is a medical condition in which the cerebrospinal fluid (CSF) surrounding the human brain and spinal cord leaks out of the surrounding protective dural sac for no apparent reason. A spontaneous CSF leak, as opposed to traumatically caused CSF leaks, arises idiopathically Con...
Medicine
C.N.S
f0250749-db8a-408a-bea7-db22d951e0af
Which of the following substances play a major role in regulating cell-cell and cell-matrix interaction in cementum?
Sharpey's fibers
Intrinsic fibers
Proteoglycans
Phosphoproteins
2c
single
null
Dental
null
07ae069c-2a0c-4e59-96f5-3f68b68a9cb4
The enzyme which transcripts a double stranded DNA copy from a single stranded RNA template molecule is:
DNA polymerase
RNA polymerase
Reverse transcriptase
Phosphokinase
2c
single
Reverse transcriptase transcripts a double stranded DNA copy from a single stranded RNA template. This enzyme is programmed to use a single-stranded RNA template, and to synthesize a complementary DNA (cDNA) strand. Ref: Measuring Gene Expression, Matthew B. Avison, 2007, Page 135
Biochemistry
null
cde539f9-8721-4835-8f38-65dbf77d1387
Most important element in treatment of diphtheria -
Antitoxin
Tetracycline
Erythromycin
Penicillin
0a
single
null
Microbiology
null
815bd485-1d12-495d-af56-ea0a26d2ead0
What is the rationale behind xenobiotic metabolism by CYP enzymes?
increases water solubility
increases lipid solubility
conversion to an active metabolite
makes it suitable to evaporate through skin surface
0a
single
the aim of xenobiotics metabolism is to increase water solubility so that these compounds can be exceed through urine. (Ref-Goodman Gillman 12th/e p124/125)
Anatomy
General anatomy
6fa5894d-c18c-44bf-950b-58759c7b2e82
Treatment of C. difficile infection
Metronidazole
Bacitracin
Nitazoxanilide
All of the above
3d
multi
Ans. d (All of the above) (Ref H-17th/820; KDT 6th!731; Table 123-2)Pseudomembranous enetrocolitis is associated with use of:Rx of Pseudomemb colitis:# Clindamycin# Metronidazole and vancomycin-drug of choice.# Aminoglycosides# Oral Rx for Cl. difficile-Asso Disease include:# Tetracyclines- Placebo or discontine offend...
Pharmacology
Anti Microbial
0b712d2d-b074-4292-b2ed-695dab0178b5
All are true about SALK vaccine except -
It prevents paralysis
Oral polio can be given as booster
It is contraindicated in immunocompromised patients
Easily transpoed
2c
multi
Ans. is 'c' i.e., It is contraindicated in immunocompromised patients Advantages of IPV 1) Being an inactivated vaccine, it is safe to administer in - i) Persons with immunodeficiency ii) Persons undergoing coicosteroid or radiotherapy iii) During pregnancy 2) One or two doses of live vaccine (OPV) can be given safely ...
Social & Preventive Medicine
null
fdae3556-d54e-4003-a755-745b409bd608
All are associated with chronic osteomyelitis except-
Amyloidosis
Sequestrum
Metastatic abnormality
Myositis ossificans
3d
multi
Complications of chronic osteomyelitis Following complications can occur : - Acute exacerbation Growth abnormalities due to damage to adjacent growth plate: - Shortening, Deformities. Pathological fracture Joint stiffness Sinus tract malignancy (very rare): - Squamous cell carcinoma Amyloidosis
Orthopaedics
null
b0a2ee6f-a113-4c92-a771-c4b7a347c477
Relationship between the disease and social conditions
Political science
Social Psychalogy
Social Pathology
Social Sciences
2c
single
null
Social & Preventive Medicine
null
f010cfa1-2d79-4d77-829f-1068cba240d4
Barbed broach is used for:
Extirpation of pulp
Enlargement of canal
Obturation of canals
All of the above
0a
multi
null
Dental
null
a9fb3bf9-0e70-4c40-b9a3-5712134443ad
Stapedius nerve is a branch of ?
Trigeminal nerve
Facial nerve
Vagus nerve
None
1b
multi
Ans. is 'b' i.e., Facial nerve Branches of facial nerve In fallopian (facial canal) :- Greater petrosal (greater superficial petrosal) nerve, nerve to stapedius, chorda tympani.At its exit from stylomastoid foramen :- Posterior auricular, digastric nerve, stylohyoid nerve.Terminal branches :- Temporal, zygomatic, bucca...
Anatomy
null
846ab131-5aee-4f5d-8e6c-4aa454f08ed6
'Intermediate form' of Non Hodgkin's lymphoma is -
Small noncleaved cell
Diffuse, small cleaved cell
Lymphoblastic
Large cell immunoblastic
1b
multi
Working formulation of NHL for clinical use is as follows: Low grade :       small lymphocytic Follicular, predominantly small cleaved cell Follicular mixed Intermediate Grade :         1. Follicular predominantly large cell 2. Diffuse small, mixed, as well as large cell. High grade :                        L...
Pathology
null
36eea033-e836-4d5d-8880-f9f6c9a89945
When a person stands suddenly from lying down posture, there is
Increased tone of capacitance vessels.
Increase efferent discharge from IX cranial nerve
Decreased heart rate
All of the above
0a
multi
(A) Increased tone of capacitance vessels. > It occurs due to noradrenergic impulses causing venoconstriction via their action on a1 and a2 - adrenergic receptors on systo veins.
Physiology
Nervous System
5951c8e6-c7e7-4104-b20d-66732a26532a
True about Trendelenburg operation is
Stripping of superficial varicose vein
Ligation of perforators
Flush ligation of superficial varicose veins
Ligation of sho saphenous vein
2c
multi
Tredelenburg Operation Consists of saphenofemoral junction flush ligation & Greater saphenous vein (GSV) stripping All four tributaries (superficial Inferior epigastric, superficial circumflex iliac, deep & superficial external pudendal veins) is divided Ligate the GSV deep to all tributaries flush with the common femo...
Surgery
Vascular surgery
10da9861-e17b-4783-a744-5cef4dcad3aa
Sub-valvular Aoic Stenosis is known to be associated with all of the following, except:
Aoic Regurgitation
Coarctation of Aoa
Tricuspid Valve Atresia
Ventricular Septal Defect
2c
multi
Answer is C (Tricuspid valve atresia) Tricuspid Valve Atresia is not associated with Subvalvular Aoic Stenosis. Subvalvular Aoic Stenosis (Subaoic Stenosis) Subaoic stenosis is defined as obstruction to left ventricular outflow below the aoic valve. It is the second most common form of fixed aoic stenosis. The most com...
Medicine
null
84a464ad-bbed-481f-8357-657edfb655ef
Incubation period of Nipah virus
4 -14 days
2 - 6 days
3 -8 days
5 - 10 days
0a
single
Ref:Park's Textbook of Preventive and Social Medicine 25th Ed Pg.310
Social & Preventive Medicine
Communicable diseases
7eaa9d3d-72e1-4211-b783-64d0d0fd214b
Drug indicated in case of subarachnoid hemorrhage:
Nimodipine
Amlodipine
Diltiazem
Verapamil
0a
single
Ans. A. NimodipineNimodipine is cerebro selective calcium channel blocker. Given in patients with hemorrhagic stroke. Nicardipine also have similar effects. This drugs reverse the cerebral vasospasm.
Pharmacology
C.V.S
ae8e864d-3b33-4585-9b33-c315fc9aa66b
Ayushman Bharat is
Health education program
Health protection scheme
Health personnel training
Health practicing guidelines
1b
single
Ayushman Bharat is National Health Protection Scheme, which will cover over 10 crore poor and vulnerable families (approximately 50 crore beneficiaries) providing coverage up to 5 lakh rupees per family per year for secondary and teiary care hospitalization. Ayushman Bharat - National Health Protection Mission will sub...
Social & Preventive Medicine
Communicable diseases
cdc933fb-e826-4cc0-9c46-019a4ef5deae
Autoimmune hemolytic anaemia is seen in:
All
AML
CML
CLL
3d
multi
About 15% of patients develop autoantibodies ( IgG )against their own red cells or platelets which leads to autoimmune hemolytic anemia.
Pathology
Chronic Lymphocytic Leukemia
14288a14-ade9-478c-bd38-deb7f28ae565
A 56-year old man presented with bony pain. X-ray skull lateral view shows:
Pagets disease
Hyper osteosis frontalis
Fibrous dysplasia
Osteopetrosis
1b
single
Ref. Grainger and Allison's Diagnostic Radiology. Page. 483   Pagets disease of bone affects each person differently . It includes : 1 Bones : Pain in the affected bones is the most common symptom of pagets disease of bone.   Skull in Pagets disease osteoporosis circumscripta: large, well-defined lytic lesion cotton ...
Unknown
null
fd1ce6b8-68c7-4bc7-b837-3acecd8fbfa3
Agoraphobia is -a) Fear of open spacesb) Fear of closed specesc) Fear of heightsd) Fear of crowded places
b
c
ad
ab
2c
single
Formerly the term agoraphobia was used to denote phobias of open spaces alone but it is now used in a wider sence, i.e. irrational fear of places and situations from where escape might be difficult. Such places are public places, stores, crowd, travelling alone in bus, train or plane or in lift.
Psychiatry
null
86cfff54-25f9-4a56-ae49-6eff0164bd54
Trapping parasites using NETs is assisted by
Neutrophils and Eosinophils
Neutrophils and Monocytes
Eosinophils and Monocytes
Nk cells
0a
single
NEUTROPHILS AND EOSINOPHILS EMPLOY NETS TO ENTRAP PARASITESIn addition to ingesting small microorganisms such as bacteria by phagocytosis, neutrophils and eosinophils can assist in the elimination of larger invaders by trapping them within webs called neutrophil extracellular traps or NETsRef: Harper&;s Biochemistry; 3...
Biochemistry
miscellaneous
c29b9c31-c62f-4cde-958c-9c67e1e3ab17
a-helix of protein is
Primary structure
Secondary structure
Teiary structure
Quaery structure
1b
single
a-Helix: A peptide chain forms regular helical coils called a-helix. Type of secondary protein structure. These coils are stabilized by hydrogen bonds between carbonyl O of 1st amino and amide N of 4th amino acid residues. Thus in a aa aa-helix intrachain hydrogen bonding is present. The a aa aa-helices can be either r...
Biochemistry
Structure and function of protein
15fb4cca-db5c-4964-bb11-99dab4915371
Common sites for mongolian spot are -
Face
Neck
Lumbosacral area
All
2c
multi
Ans. is 'c' i.e., Lumbosacral area Mongolian spots are blue or slate - gray macular lesions which occur most commonly in pre-sacral area (mainly in lower back & buttocks) but may be found over the posterior thighs, legs, and shoulders.
Pediatrics
null
37b0c653-34a8-45ff-94db-b306b8deb50d
Threshold level for neuronal action potential-
-70 mv
+70 mv
-55 mv
+55 mv
2c
single
Ans. is 'c' i.e., -55 mv * The action potential, which is recorded using an intracellular electrode, has following phases : -1) Resting stage:# This is the resting membrane potential before the action potential. At rest, membrane is said to be "polarized" because - 70 mV negative membrane potential (RMP) that is presen...
Physiology
General
24f934e7-8666-4ab6-ac41-af5b4c40ff07
Which of the following includes the classical triad of ' enlarged upper part of uterus, soft lower part of body and firm cervix 'during early pregnancy?
Hegar's sign
Jacquemier's sign
Osiander's sign
Goodell's sign
0a
single
Ans. a (Hegar's sign). (Ref Dutta, Obstetrics, 6th ed., p 65)SIGNS OF EARLY PREGNANCY1Jacquemier's or Chadwick's sign (eighth week)Dusky hue of vestibule and anterior vaginal wall.2Osiander's sign (eighth week)Increased pulsations felt through lateral fornices.3Goodell's sign (sixth week)Softening of cervix.4Piskacek's...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
b9a29ef8-a3a6-4b9c-b484-aecc49535526
All are true about Experimental trials except:
Can’t double blind in animal trials
All animal trials are unethical
Can’t do interim analysis
Are always prospective
0a
multi
null
Dental
null
2a640a66-0b7d-4b21-a3c8-a42a480d005f
Acute Hepatitis B can be earliest diagnosed by ?
IgM anti HBc ab
Hbs Ag
IgC anti HBc abs
Anti HBs Ag ab
0a
single
Ans. is 'a' i.e., IgM anti HBc Ab . This is controversial question. . Some people (including me) are in our of IgM anti HBc abs, while other think HBs Ag is the correct answer. . With HBs Ag one can make the diagnosis of HBV infection, but to confirm acute infection, IgM anti HBc is required. See following question of ...
Microbiology
null
814a98db-1062-4cb6-8106-14c1215e6c9a
Recommended reflection factors include each of the following, except –
Ceilings 80%
Roofs 40%
Walls 50 to 60%
Furnitures 30 to 40%
1b
multi
null
Social & Preventive Medicine
null