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135
6553360a-576c-46a0-9ed3-118c9cc0c85e
Which is the most common cause of male infertility
Smoking
Varicocele
Epididymitis
Idiopathic
1b
single
Varicocele is the most common cause of male infertility.
Surgery
null
b2cba28d-1f02-4b5d-86c8-a2016827a54a
Sterile vegetations are seen in all except
SLE
Infective endocarditis
Rheumatic fever
Marantic endocarditis
1b
multi
Infective endocarditis is a serious infection mandating prompt diagnosis and intervention. Microbial invasion of hea valves or mural endocardium--often with destruction of the underlying cardiac tissues--characteristically results in bulky, friable vegetations composed of necrotic debris, thrombus, and organisms.destru...
Pathology
Cardiovascular system
ecdacc04-6369-4fb1-a791-73f9a796fb2a
BASDAI criteria is indicated in
Ankylosing spondylitis
Rheumatic Ahritis
Kawasaki Disease
Any autoimmune disease
0a
single
BASDAI(Bath Ankylosing Spondylitis disease activity index) Used to know effectiveness of drug therapy On a scale of 1-10 it is measured by various factors like discomfo, pain, morning stiffness etc If the value is >4 there is suboptimal control of disease
Surgery
Trauma
27645fbc-0642-4689-8465-62e9f48af013
A patient has Rinne test +ve for left ear and weber test is lateralized to right ear, what type of deafness may be seen in this case?
Left conductive HL
Right conductive HL
Left sensorineural HL
Right sensorineural HL
2c
single
Tuning fork tests and their interpretation Test Normal Conductive deafness SN deafness Rinne AC>BC (Rinne +ve) BC>AC (Rinne -ve) AC>BC Weber Not lateralized Lateralized to poorer ear Lateralized to better ear.
ENT
DNB 2018
03116128-cd45-484a-aafc-b11f4f50b82a
The blood pressure regulatory system that is labeled as a buffer system is
Baroreceptor
Chemoreceptor
Kidney
CNS ischemic response
0a
single
Baroreceptor system opposes either increases or decreases in aerial pressure, it is called a pressure buffer system, and the nerves from the baroreceptors are called buffer nerves.Ref: Guyton and Hall textbook of medical physiology 13th edition. Page: 221
Physiology
Cardiovascular system
375bc644-1968-4f4c-91e5-fee8e160a3b2
A patient requires mild cholinomimetic stimulation following surgery. Physostigmine and bethanechol in small doses have significantly different effects on which of the following ?
Gastric secretion
Neuromuscular junction
Sweat glands
Ureteral tone
1b
multi
null
Pharmacology
null
a6e85470-310a-47ff-ac79-e6a9802d1d7e
Least common valve involved in rheumatic fever?
Aoic valve
Tricuspid valve
Mitral valve
Pulmonary valve
3d
single
Ans. is 'd' i.e., Pulmonary valve Endocarditis in rneumatic fever Mitral valve involved almost all the cases of Acute Rheumatic Fever. Almost 25% of MR is asociated with aoic regargitation. Tricuspid regurgitation is seen in 10-30% cases. Pulmonary valve involvement is never seen.
Pediatrics
null
2574b5c2-7fdc-47a5-9317-de536dd69da6
t(2,8) is associated with:
T cell ALL
B cell ALL
CML
CLL
1b
multi
t(2,8) causing translocation vetween immunoglobulins k chain on chromosome 2 and the myc gene present on chromosome 8 and is seen in Burkitts lymphoma .The translocation results in the increased expression of c-myc resulting in development of neoplasia. (ref Robbins 8th/608)
Anatomy
Haematology
859f17f6-fb76-4ed6-b791-7fa63b1c87d4
Cause of persistance of a sinus or fistulae includes?
Foreign body
Non dependentt drainage
Unrelieved Obstruction
All of the above
3d
multi
Ans. is `d' i.e., All of the above
Surgery
null
0298a527-253e-4da8-b617-00530b799454
Multiple submucosal neuromas is most likely associated with -
Multiple endocrine neoplasia type 2B
Ovarian carcinoma
Testicular teratoma
Pancreatic beta cell carcinoma
0a
single
Mucosal neuromas are made up of nerve cells, often with thickened perineurium, intewined with one another in a plexiform pattern. Multiple endocrine neoplasia type 2B is a genetic disease that causes multiple tumors on the mouth, eyes, and endocrine glands. It is the most severe type of multiple endocrine neoplasia,dif...
Medicine
Oncology
0edf59d8-0f01-48d7-9d9e-b659aa4df6ba
Baby born to DM have following except:
Hypercalcemia
Hypokalemia
Hypoglycemia
Obesity
0a
multi
null
Gynaecology & Obstetrics
null
70a6f70a-d6a6-4579-b2a4-54bce21a29b1
Daily vitamin A intake
1000 I.U
2000 I.U
3000 I.U
4000 I.U
3d
single
null
Biochemistry
null
78cbda4a-43bf-4fac-937f-ffaf87db3770
Not an indication for cholecystectomy for asymptomatic gallstones
Diabetes
Sickle cell anaemia
Procelain GB
In high prevalence areas CA GB
0a
multi
Indications of prophylactic Cholecystectomy Cardiac transplant recepients Lung transplant recipients Chronic TPN requirements Recepients of biliopancreatic diversion (bariatric patient) Children with hemoglobinopathy (sickle cell, thalassemia and spherocytosis) Asymptomatic gallstone >=3cm Stone associated with the pol...
Anatomy
G.I.T
7b6588dd-a205-4193-b1b0-ff4e388e19ea
Trident hand is seen in –
Achondroplasia
Mucopolysaccharidosis
Diphyseal achlasia
Cleidocranial dystosis
0a
single
Trident hand is seen in achondroplasia.
Radiology
null
1f44c028-cadc-44ce-a4d2-a0bbedf914fa
A Hand radiograph of a child given suggests the diagnosis of?
Scurvy
Rickets
Hyperparathyroidism
Osteogenesis imperfecta
1b
single
The Wrist radiograph shows a immature skeleton and the lower ends of radius and ulna showing cupping,splaying and fraying suggestive of Rickets
Radiology
Musculoskeletal Radiology
81823eff-fcee-4c7f-b6ad-e6f4250deeb9
Earliest feature of vitamin deficiency is:
Conjunctival xerosis
Nyctalopia
Retinopa thy
Pain
0a
single
Conjunctival xerosis
Ophthalmology
null
43f49022-83b5-40f5-967e-bd4a4d4a348c
Release of histamine and leukotrienes from mast cells is prevented by:
Zileuton
Nedocromil sodium
Zafirlukast
Fexofenadine
1b
single
nedocromil and sod.cromoglycate- mast cell stabilizers Sodium cromoglycate (Cromolyn sod.) is a synthetic chromone derivative which inhibits degranulation of mast cells (as well as other inflammatory cells) by trigger stimuli. Release of mediators of asthma-like histamine, LTs, PAF, interleukins, etc. are restricted. N...
Pharmacology
Respiratory system
eb09f8db-d795-45c2-a852-875d694abac9
Which layer involved in blister formation in a superficial partial thickness burn:
Epidermis
Dermis
Papillary dermis
Reticular dermis
2c
single
Ans. (c) Papillary dermisRef: Surgery Sixer 2nd edition, Page 892* First degree: Involves only epidermis* Second degree: Involves epidermis and some part of dermis. (Also known as partial thickness burns)Further divided into:* Superficial second degree or superficial partial thickness involves upper part of dermis* Dee...
Surgery
Plastic & Reconstructive Surgery
a2390673-39df-408a-a011-d8264a421a47
A laboratory technician was accidentally exposed to a HIV serum positive sample, which of the following shall be the role of zidovudine in treatment of this patient ?
Protects against acquiring the HIV infection
Makes the patient seronegative
Delays the progression of disease
None
0a
multi
null
Pharmacology
null
6e5be42e-f370-4272-95a6-5680d0ccb542
RBC cast is seen in?
Minimal change disease
Renal vein thrombosis
Bladder schistomiasis
Rapidly progressive Glomerulo-nephritis
3d
single
Ans. (d) Rapidly progressive Glomerulo-nephritisRef: Robbiris pathology 9th ed. /912-915* RBC casts are a feature of glomerular damage. Normally < 3 RBC/HPF are going to leak. But in case of glomerular damage the number of RBC in urine will exceed the limit mentioned above and these RBC get impinged on tamm- horsfall p...
Pathology
Glomerular Diseases
1890b3f1-1b57-437c-9d31-f2daeb309d84
A 15-year-old girl incurs a cut to the sole of her foot after stepping on a piece of broken glass. On examination, a superficial 0.5-cm laceration ceases to bleed within 5 minutes after application of local pressure. Which of the following substances is released by endothelium and is most likely to counteract platelet ...
Glycoprotein IIb/IIIa
Platelet-activating factor
Prostacyclin
Tissue-type plasminogen activator
2c
multi
Endothelial injury releases glycoprotein tissue factor (factor III) that drives the coagulation process and activates platelets. Adjacent intact endothelium generates prostacyclin (PGI2 ) via arachidonic acid metabolism to inhibit clot propagation beyond where it is needed. PGI2 and nitric oxide are powerful vasodilato...
Pathology
Hemodynamics
82163ba0-ca52-4f03-85a0-3cf21d777bbf
Large Intracytoplasmic glycogen storage is seen in which of the following malignancy -
Osteosarcoma
Mesenchymal chondrosarcoma
Ewing's sarcoma
Leiomyosarcoma
2c
single
null
Pathology
null
f89fdba6-62bb-46fd-bda5-af610b529256
3. Drug used in the Pseudomonas treatment
Cefixime
Ceftazidime
Ampicillin
Cotrimoxazole
1b
single
Psedomonas is inherently resistant to most of the antibiotics. Cephalosporins such as ceftazidime ,cefoperazone, ceftolozane and cefepime are used to treat it
Anatomy
Bacteriology
507087b4-4908-4633-a10e-5943cd2eee8a
Host receptor for streptococcus pyogenes is?
CD4
CD21
CD44
CD46
3d
single
Ans. (d) CD46(Ref: Wintrobes I2th/pg 2523)CD46 (Complement Membrane Cofactor Protein): It is a receptor to a number of pathogens, such as herpes virus 6, M protein of group A streptococci, Neisseria gonorrhoeae, and Escherichia coli.
Pathology
Misc. (W.B.C)
abb157dc-18ba-49d5-ba6e-f1abd0610d45
Aniseikonia means -
Difference in the axial length of the eyeballs
Difference in the size of cornea in both eyes
Difference in the size of pupil in both eyes
Difference in the size of image formed by the two eyes
3d
multi
Ans. (d) Difference in the size of image formed by the two eyesRef: Parsons 22/e, p. 283, 613Aniseikonia is defined as a condition where the images projected on the visual cortex from the two retinae are abnormally unequal in size or shape.
Ophthalmology
Elementary Optics
79eb80d0-7a00-4be6-98f6-0d115fa4997d
Which of the following is associated with suicide risk?
Noradrenaline
Serotonin
GABA
Dopamine
1b
single
Ans. B SerotoninLow concentrations of 5-hydroxyindoleacetic acid (5-HIAA- metabolite of serotonin) in CSF associated with higher suicide risk
Psychiatry
Mood Disorders
a5942743-3cc4-4a4b-904f-295334408bc0
Most common coagulopathy noted in surgical patients is -
Thrombocytopenia
Afibrinogenemia
Fibrinolysis
Factor VIII defeciency
0a
single
Ans. is 'a' i.e., Thrombocytopenia
Surgery
null
dd3e0f40-d128-4467-8d95-bf76ee0ed2be
Which of the following drug is a reverse transcriptase inhibitor ?
Indinavir
Ritonavir
Nelfinavir
Abacavir
3d
single
null
Pharmacology
null
048b366b-609e-4fe1-841e-7fbacdaf286a
An anterolaternal corodotomy relieving pain in right leg is effective because it interrupts the
Left dorsal column
Left ventral spinothalmic tract
Left lateral spinothalmic tract
Right lateral spinothalmic tract
2c
single
C i.e. Left lateral spinothalmic tract The anterior/ ventral - spinothalmic tract carries crude touch and pressueQ from opposite half of body; whereas lateralspinothalmic tract carries pain and temperature from the opposite half of body. Therefore any lesion in lateral spinothalmic tract will result in loss of pain and...
Anatomy
null
db65f0d5-ec29-40b0-8622-695c4e98cb1e
Features of Alzheimer include all except
More common in females
Recent memory loss
MMSE useful in diagnosis
Medications offer near 100% cure
3d
multi
Dementia is a chronic organic mental disorder, characterized by the following main clinical features: 1. Impairment of intellectual functions, 2. Impairment of memory (predominantly of recent memory, especially in early stages), 3. Deterioration of personality with lack of personal care. Reference: A sho textbook of Ps...
Psychiatry
Organic mental disorders
491a7cd5-2279-4d87-979d-023a778b78db
A Neonate is brought with history of not having passed meconium on examination there is no anal opening but a dimple. Investigation of choice is -
X-ray erect posture
X-ray supine posture
Gastrograffin study
Invertogram
3d
single
• Anorectal malformations are associated with VACTERL abnormalities.
Surgery
null
02200fb4-27cc-4305-8fb4-7fe4808c06e1
M.C. organism in acute osteomyelitis -
Staphylococcus aureus
Salmonella
Pseudomonas aeruginosa
Streptococcus pneumonia
0a
single
Ans. is 'a' i.e., Staphylococcus aureus o Acute osteomyelitis may be : -Primary (hematogenous) : - Organisms reach the bone through blood stream.Secondary: - Organism gain emery directly through wound such as in compound fractures or surgical operation,o Hematogenous osteomyelitis is the commonest form of osteomyelitis...
Orthopaedics
Infection of Bones & Joints
e2cb5ab2-7ce9-4284-9e03-aa5271277b61
Surgical ciliated cyst is often associated with surgeries of the
Maxillary impaction
Mandibular set back
Caldwell Luc procedure
mucocele
2c
single
null
Surgery
null
c524b80b-8102-4219-b13a-63fd276b9417
Meningococci differs from gonococci in that they
Are intracellular
Possess a capsule
Cause fermentation of glucose
Are oxidase positive
1b
single
Meningococci are capsulated, unlike gonococci. Based on their capsular polysaccharide antigens, they are classified into at least 13 serogroups, of which A, B, C, X, Y and W-135 are most impoant. Reference: Textbook of Microbiology; Anathanarayan and panicker's; 10th edition; Page no: 230
Microbiology
Bacteriology
fbc058c1-41e7-447c-b399-ae85cf9edc26
Which of the following structures passes behind the inguinal ligament? 1. Femoral branch of genitofemoral nerve 2. Superficial epigastric aery 3. Psoas major 4. Femoral vein 5. Saphenous vein
1,2 & 3
3 & 4
1,3,4 & 5
All
1b
multi
Three small cutaneous aeries (superficial external pudendal, superficial epigastric and superficial circumflex iliac aeries) arising from the femoral aery can be seen a little below the inguinal ligaments.Femoral branch of the genitofemoral nerve pierces the femoral sheath and overlying deep fascia 2 cm below the mid i...
Anatomy
null
bd0e5286-b52a-49c6-a014-5b245dcd17f9
Which of the following best responds to sympathectomy?
Buerger's disease
Hyperhydrosis
Raynaud's disease
Acrocyanosis
1b
single
Hyperhydrosis responds best to sympathectomy . Indications of Sympathectomy (BARA CHEF) Buerger's disease Atherosclerosis producing ischemia of limbs Raynaud's disease Acrocyanosis Erythrocyanosis Frost bite Hyperhydrosis Peripheral vascular insufficiency Causalgia
Surgery
Aerial disorders
73beb125-23e1-4ec0-b63a-b191cb6c60cf
Which is the immunoglobulin which activates complement by alternate pathway?
Ig E
Ig A
Ig M
Ig G
1b
single
The central process in the complement is the activation of C3 which is the major component of complement. In classical pathway, activation of C3 is achieved by C42 (C3 convease). The activation of C3 without the prior paicipation of C142 is known as alternate pathway. The first example of alternate pathway was that of ...
Microbiology
null
78c57e83-d210-4ded-96ca-ba1deba007a4
Propaganda is defined as –
Forcing of knowledge into mind
Active aquiring of knowledge
Requiring knowledge after thinking
Training of people to use judgment before acting
0a
single
Health education : Facilitate learning Propaganda or publicity : Knowledge instilled in the mind of people.
Social & Preventive Medicine
null
693cf8db-f1ae-4939-9130-da5a5fb23250
K nail work on the pricliple of -
One point fixation
Two point fixation
Three point fixation
Four point fixation
2c
single
Ans. is 'c' i.e., Three point fixation * K-nail is used for transverse or short oblique fracture of femur, especially in isthemic area.* K-nail (Kuntscher cloverleaf intramedullary nail) provides three points fixation due to elastic deformation.* These three points of fixation are both ends of bone (2 points) and isthm...
Orthopaedics
Management In Orthopedics
326dff05-eb4e-403b-8449-136265f44e71
Anemia in chronic renal failure is due to
Decreased erythropoietin production
Iron deficiency
Hypoplastic bone marrow
Decreased folate levels
0a
single
Ref Harrison 19 th ed pg 630 The anemia is primarily due to a failure of EPO production by the diseased kidney and a reduction in red cell survival. In ceain forms of acute renal failure, the correlation between the anemia and renal function is weaker. Patients with the hemolytic-uremic syndrome increase eryth- ropoies...
Anatomy
Haematology
1a15e330-8e55-4c23-bb37-4568776f5f57
Primordial prevention is done in a population
With risk factors
Without risk factors
With low prevalence of disease
With disease
1b
single
Primordial prevention aims at preventing the emergence of risk factors. This is the primary prevention in its purest sense, that is, prevention of emergence or development of risk factors in countries or population groups in which they have not yet appeared. Ref: Park's Textbook of Preventive and Social Medicine; 24th ...
Social & Preventive Medicine
Concept of health and disease
3297104e-f989-43d3-ba78-3e45f525fe8c
If you are suspecting a child to have Congenital Hypertrophic Pyloric Stenosis clinically. Next, the best investigation is?
Barium meal
USG
CT
MRI
1b
multi
ANSWER: (B) USGREF: Schwartz's 9th ed chapter 39, Sabiston Surgery, 18th edition, Page 2058,2059See details of Congenital hypertrophic pyloric stenosis in Surgery 2007See PLATER-38 KEY PLATER-38 KEYHYPERTROPHIC PYLORIC STENOSISContrast study:Elongation + narrowing of the pyloric canal (2-4 cm in length)Double/triple tr...
Unknown
null
59061af5-4aad-4d6e-93d9-d172c6c66549
Which of the following is not true regarding "thumb sucking"
Feels insecurity
Pleasurable sensation
Leads to dental problems
None
3d
multi
Ans. is None
Pediatrics
null
e4b8bafb-bc5c-4757-83ad-037c00fa11a2
DNA fingerprinting is based on possessing in DNA of -
Constant Tandem Repeat
Variable Number Tandem Repeats (VNTR)
Non-repeatative sequence
Exon
1b
single
Variable number of tandem (one after another) repeats (VNTR), is unique for any individual & therefore serves as molecular DNA fingerprint. VNTR may be short tandem (microsatellite) or large tandem (minisatellite) repeats.
Biochemistry
null
92101996-5056-435e-9091-35abdad25fc9
Olympian f"-ow and I hi:odes
CMV inclusion disease
Ectodermal dysplasia
Congenital syphilis
Hyper IgE syndrome
2c
single
Ans. c. Congenital syphilis Clinical Presentation of Syphilis Early Congenital Syphilis: Snuffles (rhinitis)Q is earliest feature. Lesions are vesicobullousQ, and snail track ulcers on mucosa Clinical Presentation of Syphilis Late Congenital Syphilis: Characterized by Hutchinson's triad (interstitial keratitis + 8th ne...
ENT
null
b79492e4-22b2-4d06-a163-a67f99da0ed5
Which of the following is the LEAST likely physiological change in pregnancy?
Increase in intravascular volume
Increase in cardiac output
Increase in stroke volume
Increase in peripheral vascular resistance
3d
single
Blood volume expansion begins early in the first trimester, increases rapidly in the second trimester, and plateaus at about the 30th week. Cardiac output increases approximately 40% during pregnancy, with maximum values achieved at 20-24 weeks' gestation. Stroke volume increases 25-30% during pregnancy, reaching peak ...
Gynaecology & Obstetrics
null
30d2513b-c3b8-487a-9d58-ff1a57ea039e
A patient is a known case of polyarteritis nodosa. On examination of biopsy, accumulation of amorphous, basic, proteinaceous material in the vessel wall was seen. This finding is suggestive of:
Fibrinoid necrosis
Leucocytoclastic vasculitis
Hyaline arteriosclerosis
Caseous necrosis
0a
multi
Ans. (a) Fibrinoid necrosisFibrinoid necrosis is a form of necrosis, or tissue death, in which there is accumulation of amorphous, basic, proteinaceous material in the tissue matrix with a staining pattern reminiscent of fibrin.How to differentiate from hyaline arteriosclerosis?- please remember in fibrinoid necrosis, ...
Pathology
C.V.S
6e060086-aa82-46a3-9ca8-002ac9a941b8
Post exposure immunization is given in -a) Rabiesb) Pertussisc) Measlesd) Yellow fever
b
ac
ab
bd
1b
single
null
Social & Preventive Medicine
null
73905f18-3a06-4f45-b8d5-5df553438642
Inhibition of glycolysis by increased supply of 02 is called ?
Crabtree effect
Pasteur effect
Lewis effect
None
1b
multi
Ans. is 'b' i.e., Pasteur effect Pasteur effect It has been observed that under anaerobic condition a tissue or microorganism utilizes more glucose than it does under aerobic conditions. It reflects inhibition of glycolysis by oxygen and is called pasteure effect. The Pasteur effect is due to inhibition of the enzyme p...
Biochemistry
null
7ae763ce-fb83-4025-8834-2535363cfbce
The technique of laparoscopic cholecystectomy was first described by
Eric Muhe
Philip Moure
Ku semm
Eddie Reddick
0a
single
History of Laparoscopic Cholecystectomy Dr. Ku Semm, the father of 'Pelviscopy', performed the first laparoscopic appendectomy in 1980 Eric Muhe performed the first laparoscopic cholecystectomy in 1982. He used a modified operating laparoscope placed at the umbilicus after establishing pneumoperitoneun In 1987, Phillip...
Anatomy
G.I.T
7595f69c-d234-485c-a53c-f6f32558e294
Which of the following is the most common form of persistent trophoblastic disease that follows a non molar pregnancy?
Choriocarcinoma
Invasive mole
Placental site trophoblastic tumor
Paial mole
0a
single
Gestational trophoblastic neoplasia (GTN) Invasive mole: Develops after molar pregnancy only. Very rarely follows other gestations PSTT (Placental Site Trophoblastic Tumor): may follow any type of gestation Choriocarcinoma: 2/3rd cases after normal delivery, 1/3rd cases after molar pregnancy Epitheloid Trophoblastic tu...
Gynaecology & Obstetrics
Twin Pregnancy, Molar Pregnancy, Gestational Trophoblastic disease and contraception in special situations (Sour Grapes!)
46f077c2-55be-4506-accd-9d88bbb504d4
All of the following can cause megakaryocytic thrombocytopenia, except:
Idiopathic thrombocytopenia purpura
Systemic lupus erythematosus
Aplastic anemia
Disseminated intravascular coagulation (DIC)
2c
multi
Disseminated Intravascular Coagulation (DIC) DIC is an acute, subacute, or chronic thrombohemorrhagic disorder characterized by the excessive activation of coagulation and the formation of thrombi in themicrovasculature of the body. It occurs as a secondary complication of many different disorders.Patients with DIC can...
Pathology
Bleeding disorder
4eca9834-7ec0-4163-bc74-80a90a842f21
A person had an accident and came to casualty with contusion on left precordium. There was decrease in breath sounds on left side, trachea deviated to right side and normal heart sounds. Which of the following is the first line of management?
Needle thoracocentesis
Chest tube thoracocentesis
Pericardiocentesis
Open surgery
0a
single
Ans. (a) Needle Thoracocentesis* History is clearly indicative of Tension Pneumothorax- hence urgent need is Thoracocentesis at 2nd ICS. MCL.
Surgery
Trauma
e8f64a7d-2bd3-4772-8989-2a4bb0e06096
Spastic paraplegia is caused by all of the following, except:
Lead poisoning
Cervical spondylosis
Vitamin B12 deficiency
Motor neuron disease
0a
multi
Cord compression due to Cervical spondylosis, sub acute combined degeneration of cord due to vitamin B12 deficiency, and motor neuron disease involving the upper motor neuron's are all established cause for spastic paraplegia. Causes of spastic paraplegia includes: Thrombosis of anterior spinal aery Inflammation of cor...
Medicine
null
3064cd1f-d9a3-4830-a969-e6b1324abef7
Arrange the following tooth in the order of age of eruption of temporary teeth Upper lateral incisor Lower lateral incisor Lower medial incisor Upper medial incisor
1-2-4-3
3-2-1-4
3-4-1-2
2-3-4-1
2c
single
Eruption sequence of Temporary Dentition Lower medial incisor 6 to 8 months Upper medial incisor 7 to 9 months Upper lateral incisor 7 to 9 months Lower lateral incisor 10 to 12 months First molar 12 to 14 months Canine 17 to 18 months Second molar 20 to 30 months
Forensic Medicine
Human identification
d322f687-c57a-4362-9756-e2e0db75919c
The earliest manifestations of increased intracranial pressure following head injury is :
Ipsilateral papillary dilatation
Contralateral papillary dilatation
Altered mental status
Hemiparesis
2c
single
Answer is C (Altered mental status) : `Early signs of elevated ICP include drowsiness and a diminished level of consciousness (altered mental status). Coma and unilateral papillary changes are late signs and require immediate intervention.' -Harrisons
Medicine
null
36fca4ec-e72f-4b12-bc05-73fdafdccf71
All are the pharmacologic therapeutic options for achalasia, EXCEPT:
Nitrates
Beta blockers
Botulinum toxin
Sildenafil
1b
multi
Pharmacologicals therapies are usually ineffective. They can be used as a temporary measures. The agents used are: 1. Nitrates 2. Calcium channel blockers 3. Botulinum toxin 4. Sildenafil- phosphodiesterase inhibitors, effectively decrease LES pressure. Botulinum toxin, injected into the LES under endoscopic guidance, ...
Medicine
null
f950fd08-7047-4b36-8ec4-4070291c14ea
A 25-year-old male presented with painless testicular swelling and with history of fever and weight loss. All the following investigations are indicated in this patient, except:
USG scrotum
CT abdomen and pelvis
Chest x-ray
Trans-scrotal biopsy
3d
multi
Ans. (d) Trans-scrotal biopsyRef: Bailey and love, 26th Edition, Pages 1385-1388* Painless testicular swelling in a 25 male with history of fever and weight loss amounts to a diagnosis of malignant testicular swelling, i.e. testicular cancer.* To confirm the histopathological evidence of testicular cancer, orchidectomy...
Surgery
Urethra & Penis
b107dcff-c435-420a-972f-f91628165c77
Fat content is highest in _____-
Beef
Mutton
Chicken
Fish
0a
single
Fat content is highest in beef. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION.PAGE NO - 582
Social & Preventive Medicine
Nutrition and health
c5c69e5a-0a01-4248-99cd-7ce2972baaa6
In Scaphoid fracture, impoant views are all except:
AP
Lateral
Oblique
Cone
3d
multi
D i.e. Cone
Surgery
null
aba545c4-8c29-473c-9686-f547959d5eca
Miyagawa body is characteristically seen in
Kala azar
Syphilis
Granuloma inguinale
LGV
3d
multi
(D) LGV # MIYAGAWA BODIES:> Chlamydia trachomatis (Miyagawa Nella lymphogranulomatosis), the elementary bodies that develop in the intracytoplasmic mi- crocolonies of Lymphogranuloma Venereum.> Lab diagnosis of LGV (Lymphogranuloma Venereum):> The primary lesion usually goes unnoticed and the disease is seen commonly f...
Skin
Miscellaneous
359068eb-8bf2-4571-9092-40b6fdc100ed
Tom smith's arthritis is due to -
Pyogenic infection in infancy
TB
RA
OA
0a
single
Ans. is 'a' i.e., Pyogenic infection in infancy Tom smith arthritis (septic arthritis of infancy)o Tom smith arthritis is the septic arthritis of hip joint, occurs in infancy. At this stage head of the femur is cartilaginous and is rapidly and completely destroyed by the pyogenic process. Onset is acute with abscess fo...
Orthopaedics
Infective Arthritis
3f885a29-7ba3-4a15-ae4f-386df0545d5e
8 days after cesarean section a new mother presented with fever of 101.4degF. On examination her uterus is soft and extremely tender. Puerperal infection is confirmed. She mostly have:
Vaginitis
Endometritis
Parametritis
Salpingitis
1b
single
Most women with fever in the postpaum period have endometritis. Urinary tract infection is the next most common infection. caesarean section is easily the most common identifiable risk factor for development of puerperal infection. Fever and a soft, tender uterus are the most prominent signs of endometritis. Risk facto...
Gynaecology & Obstetrics
null
98a251f1-f206-4b59-aac2-f1669a108ece
Montgomery tube used in ENT procedure is a:
Double barrel tub
Lobster tail tube
Airway tube
Silicone tube
3d
single
Montgomery tracheal tube is designed to give the surgeon a complete program for creating a secondary airway-from initial incision through long-term tracheostomy care. It is a tracheal cannula system used in place of tracheostomy tubes. The system provides long-term access to the tracheal airway in situations that requi...
ENT
null
7010d5ab-cbed-49ae-a461-c31a44f8c5ae
Following are the propeies of Biguanides, EXCEPT:
Decrease hepatic gluconeogenesis
Not contraindicated in renal dysfunction
Can be used along with sulfonylureas
Don't stimulate insulin Release
1b
multi
Biguanides are contraindicated in patients with renal failure, congestive hea failure, alcoholism and hepatic diseases. Ref: Richard Finkel, Michelle Alexia Clark, Pamela C. Champe, Luigi X. Cubeddu (2009), Pharmacology, 4th Edition, Lippincott Williams and Wilkins Publications, United States Page 292
Pharmacology
null
fc7760f3-17a1-4a21-a65f-baa50d529373
Difference between active & resting cell depend on which phase of cell cycle:
G0
G1
G2
M
0a
single
Ans; A (G0) "The cell cycle consists of G, (presynthetic), S (DMA synthesis), G, (premitotic), and SI (mitotic) phases.Quiescent cells are in a physiologic state called Ga. Tissues may be composed primarily of quiescent ceils in Gv but most mature tissues contain some combination of continuously dividing cells, termina...
Pathology
Cellular Pathology
6f2aaa53-af9e-4e71-b91f-22bcce256ffb
Vascular complications of acute pancreatitis include the following except -
Splenic vein thrombosis
Splenic artery aneurysm
Gastroduodenal artery aneurysm
Middle colic artery thrombosis
3d
multi
Acute pancreatitis is rarely associated with arterial vascular complications. MC vessel affected: Splenic artery. Other vessels: Superior mesenteric, cystic, and gastroduodenal arteries. Vascular Thrombosis Pancreatic inflammation can produce vascular thrombosis. MC affected vessel: Splenic vein. In severe cases, it ...
Surgery
null
42ca0f7b-4904-48b9-9d1c-f4f85ef871c0
The drug that is never advised in pregnancy is:
Methotrexate
Cyclosporine
Chloroquine
Pyrazinamid
0a
single
Methotrexate is a analogue of folic acid and it prevents the synthesis of DNA by inhibiting the enzyme dihydrofolate reductase. It has been extensively used in medical termination of pregnancy, ectopic pregnancy, gestational trophoblastic disease and placenta accreta. It has been included in the "Category X" of the FDA...
Gynaecology & Obstetrics
null
57e9823a-e879-4af7-867f-aa027221e26a
Graft versus host disease is due to ?
Immunocompetent T cells in graft tissue
Immunocompetent T cells in host
Immunocompetent B cells in graft tissue
Immunocompetent B cells in host
0a
single
Ans. is 'a' i.e., Immunocompetent T cells in graft tissue Graft versus host disease Graft versus host disease occurs in any situation in which immunologically competent cells or their precursors are transplanted into immunologically crippled patients and the transferred cells recognize alloantigens in the host. Graft v...
Microbiology
null
1a05577c-55fb-4ebd-84f2-aee707b27f16
All the following Vasculitis causes necrotizing inflammation
Polyarteritis nodosa
Wegener's granulomatosis
Kawasaki disease
Microscopic polyangitis
2c
multi
Kawasaki disease - Only one Vasculitis non-necrotising.
Medicine
null
394cabfa-8810-4180-b576-e84554639ad1
The congenital Anomaly of Gallbladder shown here is
Septum
Diverticulum
Normal
Phrygian cap
3d
multi
Ans. (d) Phrygian cap* Phrygian Cap anomaly is the MC congenital anomaly of GB in which the Fundus of Gallbladder folded upon itself.
Surgery
Gall Bladder & Bile Ducts
bd6bccc8-1257-4eae-867f-63195f73879e
Painless burn in hand is seen in:
SLE
Syringomyelia
Mononeuritis multiplex
Diabetes mellitus
1b
multi
Syringomyelia is associated with Arnold Chiari malformation type 1 IOC: - MRI spine
Medicine
FMGE 2017
d9ae47c5-3868-4669-9089-b0bf89e14a54
A sewerage worker presents to OPD with acute febrile illness alongwith jaundice and conjunctivitis. His blood sample was taken and sent to lab . Lab findings are suggestive of kidney failure and elevated hepatic enzymes. Which of following is likely diagnosis ?
Malaria
Leptospirosis
Peussis
Typhoid
1b
single
Given scenario suggests diagnosis of Weil's disease/ Ictero-haemorrhagic disease/ Leptospirosis Leptospirosis - Caused by Leptospira interrogans Leptospira is an actively motile spirochete Mode of transmission: Zoonotic , by contact with water or moist soil contaminated with rat's urine or dead rats. 3 R associated wit...
Microbiology
Systemic Bacteriology (Haemophilus, Yersinia, Spirochaetes, Ricketssia, Chlamydia, Mycoplasma and Miscellaneous Bacteria)
cb229460-76f8-4706-aabd-49bfcf2ac14b
The most common congenital esophageal anomaly is which of the following?
Esophageal atresia
Esophageal psuedodiveiculum
Congenetal web
Schatzki ring
0a
single
The most common congenital esophageal anomaly is esophageal atresia, occurring in about 1 in 5,000 live bihs. Reference: Harrisons Principles of Internal Medicine, 18th Edition
Medicine
null
56b0eab5-b49b-4a2d-86f5-2b272fdbdc11
The best site to obtain a swab in acute symptomatic gonorrhea is:
Endocervix
Exudate after prostatic massage
Lateral vaginal wall
Posterior fornix
0a
multi
The best site to obtain a swab in acute symptomatic gonorrhea is Endocervix Diagnosis of Gonococcal infection: Acute Gonorrhea: Chronic Gonorrhea: a) Endocervical Culture - 80-90% sensitivity b) Urethral Discharge - 50% Sensitivity c) Rectal swab a) Morning drop secretion b) Exudate after prostatic massage c) Centrifug...
Microbiology
Systemic Bacteriology Pa 1 (Gram Positive Cocci, Gram Negative Cocci)
a3030f62-fce5-4ba5-ab7f-beff8dd6b542
All are true about chaperones except
Cause folding of proteins
Are lipid in nature
May have ATPase activity
Include heat shock proteins
1b
multi
chaperones are proteins that assist the covalent folding or unfolding and the assembly or disassembly of other macromolecular structures. Chaperones are present when the macromolecules perform their normal biological functions and have correctly completed the processes of folding and/or assembly. The chaperones are con...
Biochemistry
Metabolism of nucleic acids
5fea06ae-c794-427c-aa17-5fc64d69718e
Millennium Development goals are to be achieved by: March 2012
2005
2010
2015
2020
2c
single
Ans: C i.e. 2015 Governments have set a date of 2015 by which they would meet the Millennium Development Goals/ MDGs, i.e. eradicate extreme povey and hunger; achieve universal primary education; promote gender equality; improve maternal health; combat HIV/ AIDS, malaria and other communicable diseases; ensure environm...
Social & Preventive Medicine
null
9c6d744e-6f6b-4c65-b3ed-d52475d10d4b
Most dicient larval control method ent transmission of urban malaria:
Covering overhead tanks
Cleaning of drains
Filling of ditches and cesspools
Uprooting of plants
1b
single
Ans. b. Cleaning of drains
Social & Preventive Medicine
null
636d6e7c-212d-4411-88e8-453f5685ca9d
Mood congruent delusion seen in Depression
Delusion of grandeur
Delusion of nihilisim
Delusional parasitosis
Delusion of reference
1b
single
Nihilistic delusion is seen severe depression where patient denies the existence of himself & world. Also called as "Cotard syndrome".
Psychiatry
null
95bc9027-5a53-442b-b6d3-c479cc4a59bc
A 46-year-old man sustains a spider bite on his upper eyelid, and an infection develops. The physician is very concerned about spread of the infection to the dural venous sinuses of the brain emissary veins. With which of the following dural venous sinuses does the superior ophthalmic vein directly communicate?
Cavernous sinus
Occipital sinus
Sigmoid sinus
Superior petrosal sinus
0a
single
The anterior continuation of the cavernous sinus, the superior ophthalmic vein, passes through the superior orbital fissure to enter the orbit. Veins of the face communicate with the superior ophthalmic vein. Because of the absence of valves in emissary veins, venous flow may occur in either direction. Cutaneous infect...
Anatomy
null
eb5981c0-5a4c-4a9a-9d70-6a2aed54cda8
Distichiasis is
Increased number of lashes in the lower eyelid
Growth of eyelashes from Meibomian Orifices
Hyperpigmentation of eyelashes
Increased thickness of eyelashes
1b
single
Answer- B. Growth of eyelashes from Meibomian OrificesDistichiasis is a rare disorder defined as the abnormal grorvth of lashes from the orifces of the meibomian glands on the posterior lamella of the tarsal plate.
Ophthalmology
null
76eef1b4-1973-4ce9-ad85-1fe55a55e0f1
Change in length of upper anterior teeth in complete denture teeth setting, which sounds are affected:
f, v
d, t
Dentoalveolar sounds
b, p, m
0a
single
null
Dental
null
99285b60-26e9-4e92-b212-91febc803b29
A very ill 3-year-old child is brought into the emergency room with a fever. On physical examination, the child has large cervical lymph nodes and a desquamating skin rash that involves the palms, soles, and mouth. This child should be monitored for the development of which of the following conditions?
Abdominal aoic aneurysm
Aneurysm of the aoic root
Berry aneurysm
Coronary aery aneurysm
3d
single
The child has Kawasaki's syndrome (mucocutaneous lymph node syndrome). In this disorder, small, medium, and large aeries are affected, with transmural inflammation and variable necrosis. About 20% of affected children have damage to the coronary vessels; some develop coronary aery aneurysms. In 1-2% of cases, sudden de...
Pathology
null
38ab88c6-9a02-48b6-bf3f-22dead1b52c1
All of the follow ing are risk factors for carcinoma gall bladder, except -
Typhoid carriers
Adenomatous gall bladder polyps
Choledochal cysts
Oral contraceptives
3d
multi
Ans. is 'd' i.e., Oral contraceptives No risk of Ca G.B. has been noted with the use of oral contraceptiveso Risk factors for Ca Gall bladder are :i) Gall stonesApproximately 90% of patients with Ca GB have gall stonesSize of the stone has a direct relationship with development of carcinoma, the risk is ten times more ...
Pathology
Disorders of Gallbladder and Extrahepatic Biliary Tract
ec11ccad-6faa-4e2a-82bb-1569a9836dcf
Peripheral pulmonic stenosis is associated with
Subaoic stenosis
Takayasu's aeritis
William syndrome
Coarctation of syndrome
2c
single
Answer is C and E (William syndrome and Rubella) Peripheral pulmonic stenosis is often associated with various congenital and acquired conditions including Rubella and williams syndrome.
Medicine
null
3941f530-4ec6-4be6-af7d-a132197c625e
Helmet Cells are characteristic of
Hemolytic uremic syndrome
Polysplenia
Spherocytosis
Acanthocytosis
0a
single
Schistocytes are typically irregularly shaped, jagged, and have two pointed ends. A true schistocyte does not have central pallor. Helmet cells are also known as schistocytes / triangle cells / burr cells are a Feature of microangiopathic diseases including disseminated intravascular coagulation (DIC), thrombotic micro...
Pathology
null
fdfdc54c-df08-4f84-b066-7a2f244abe8a
Blisters are seen in
1st degree burn
Superficial 2nd degree burn
Deep 2nd degree burn
3rd degree burn
1b
single
Superficial second degree burns Involve upper layer of dermis (papillary dermis) Erythematous Blisters are seen Blanch to touch Painful Heals without scarring in 7-14 days Ref: Sabiston 20th edition Pgno :506-507
Surgery
General surgery
6bd16a82-bf65-4771-867e-24cbafdc6522
Fetal and maternal blood can be differentiated by
Kleihaurbetke test
Apt test
Bubbling test
Osmotic fragility test
1b
single
Apt testKleihauer-Betke testSource of SampleMaternal or NeonatalMaternalPrincipleAdding 1% NaOH destroys adult HbA but not fetal HbFAdding acid destroys adult HbA but not fetalHbFAssessment TypeQualitativeQuantitativeResultPositive means blood is of fetal originRepoed in estimated milliliters of fetal bloodNote:When fe...
Pathology
All India exam
4a5d2acf-e102-4a0c-a422-86c45db0509a
A child with pyoderma becomes toxic and presents with respiratory distress. His chest radiograph shows patchy areas of consolidation and multiple bilateral thin-walled air containing cysts. The most likely etiological agent in this case is –
Mycobacterium tuberculosis
Staphylococcus aureus
Mycobacterium avium intracellulare
Pneumocystis carinii
1b
multi
Pneumonia with pneumatoceles (multiple thin-walled breaths of air containing cysts) is s/o staphylococcal pneumonia. Clinical features of staphylococcal pneumonia The illness usually follows upper respiratory tract infection, pyoderma or another associated purulent disease. Besides the usual features of pneumonia chi...
Pediatrics
null
32bab35a-c62d-4485-88a5-39c98c199412
Counter transference is -
Patient's feelings towards therapist
Doctor's feelings towards the patient
Psycic connection between patient and diseas
Type of Defence mechanism
1b
single
Ans is 'b' i.e. Doctor's feelings towards the patient TransferenceTransference is the phenomenon whereby unconsciously transfer feelings and attitudes from a person or situation in the past on to a person or situation in the present. The process is at least partly inappropriate to the present.Characteristic features of...
Psychiatry
Psychoanalysis and Psychotherapy
c16dcef6-d6c0-4d0a-a28d-0f8b46d3732f
Phase 4 clinical trials is carried out:
Before the marketing approval of a drug
After a drug is marketed
For drugs used in rare disease
For drugs used in pediatric patients
1b
single
A new drug/ vaccine is launched in the market after phase III (RCT). Phase IV is 'Post marketing surveillance phase' Is the longest phase in a clinical trial. Should be carried out life long (minimum 10-25 years). Is done for finding 'long term side effects and rare side effects' of the drug.
Social & Preventive Medicine
RCT, Trials
1468c629-941d-4e6e-babd-0254b0f7a2db
RET proto oncogene is located on which chromosome:
9
10
11
12
1b
single
b. 10(Ref: Nelson's 20/e p 595)Important genes and their chromosomal location:Gene (Associated diseases)Chromosomal locationRb (Retinoblastoma)13q14.3p53 (Li-Fraumeni syndrome, sarcomas)17q13.1APC (Carcinoma Colon)5q21NF1 (Neurofibromatosis 1)17q11NF2 (Neurofibromatosis 2)22p12WT1 (Wilm's tumor)11p13RET (MEN2 syndrome)...
Pediatrics
Genetics And Genetic Disorders
6c6a45c8-5e43-45f5-87bb-f0756a61e4f5
With reference to neoplasia, the term 'tumor progression means
Spread of cancer to distant sites
Rate of growth of tumors
Abi1ity of cancer cells to resemble their normal counterpa
Sequential appearnace of features of increasing malignancy
3d
single
Multi step.theory of carcinogenesis Phy.attributes are .self sufficient in growth signal .local invasion ,metastasis .karyotic pattern .hormonal response .response to Anti malignant drugs Evading apoptosis All these acquired in a step wise fashion This phenomenon is tumour progression
Pathology
Cardiovascular system
0ea6d3bd-97f5-4556-9977-b73ada18c177
Which of the following statements about Xanthogranulomatous is not true -
Foam cells are seen
Associated with tuberculosis
Yellow nodules are seen
Giant cells may be seen
1b
multi
Xanthogranulomatous pyelonephritis is relatively rare form of chronic pyelonephritis charecterized by accumulation of foamy macrophages intermingled with plasma cells ,lymphocytes,polymorphonuclear leukocytes, and occational giant cells.Often associated with Proteus infections and obstruction,the lesions sometimes prod...
Pathology
Urinary tract
f21547d8-ecc7-41ed-b388-25822cd33e33
All of the following are clinical features of myxoma, EXCEPT:
Fever
Clubbing
Hypeension
Embolic phenomenon
2c
multi
Myxomas are benign cardiac tumors. Most commonly it arise from the endocardial surface of the left atrium, and with a stalk it is attached to the interatrial septum close to the fossa ovalis. Myxomas present with obstructive symptoms and signs, and may be sudden in onset or positional in nature, owing to the effects of...
Medicine
null
6ca3ad9e-ae6c-4264-94c6-05134f985c93
Mesentric tumours are
Usually solid
Usually cystic
Highly malignant
Highly vascular
1b
multi
Mesenteric cysts and cystic mesenteric tumors are very rare abdominal growths. They may be localized all over the mesentery, from duodenum to rectum, however, they are mostly found in the ileum and right colon mesentery. There are several classifications of these formations, among which the one based on histopathologic...
Pathology
G.I.T
e0366bbf-9174-467b-9b21-aedd32d8d832
A 60 yr old smoker came with the history of painless gross hematuria for one day. The investigation of choice would be :
Urine routine and microscopy
Plain x-ray KUB
USB KUB
Urine for malignant cytology
3d
single
null
Surgery
null
6e12ed27-2d52-4839-8e73-72334e834d44
A patient with autoimmune thyroditis present with hypothyroidism. Which of the following is true
Thyroid peroxidase antibodies
Painless enlargement of thyroid
Common in men
No malignant risk
0a
multi
The major cause of hypothyroidism in adults is Hashimoto thyroiditis, autoimmune-mediated destruction of thyrocytes. The disorder predominates in women Presence of TSH-blocking antibodies, such as thyroid peroxidase antibodies, can be detected The onset, thyroid status and the type of goitre vary profoundly from case t...
Surgery
Endocrinology and breast
793e77d8-2a03-4f1f-8218-758ae58f9fb2
One of the following disease will show urinary bladder calcification radiologically which resembles fetal head in pelvis:
Tuberculosis
Schistosomiasis
Chronic cystitis
Malignancy
1b
multi
A plain film of the abdomen may show areas of grayness in the flank (enlarged hydronephrotic kidney) or in the bladder area (large tumor). Opacifications (stones) may be noted in the kidney, ureter, or bladder. Linear calcification may be seen in the ureteral and bladder walls. Punctate calcification of the ureter (ure...
Surgery
null
42704339-3d53-479b-be41-bb9bd4425157
A 20-year-old woman complains of weakness that is worse in the afternoon, worse during prolonged activity, and improved by rest. When fatigued, the patient is unable to hold her head up or chew her food. She often notes diplopia when driving home from work. On physical examination, she has no loss of reflexes, sensatio...
Autoantibodies directed against the postsynaptic acetylcholine receptor causing neuromuscular transmission failure
Destruction of anterior horn cells by virus
Progressive muscular atrophy caused by spinal degeneration
Demyelinating disease
0a
single
The disease process described is myasthenia gravis (MG), a neuromuscular disease marked by muscle weakness and fatigability. Myasthenia gravis results from a reduction in the number of junctional acetylcholine receptors as a result of autoantibodies. Antibodies cross-link these receptors, causing increased endocytosis ...
Medicine
C.N.S.