id
stringlengths
36
36
question
stringlengths
1
1.57k
opa
stringlengths
1
287
opb
stringlengths
1
287
opc
stringlengths
1
286
opd
stringlengths
1
301
cop
class label
4 classes
choice_type
stringclasses
2 values
exp
stringlengths
1
22.5k
subject_name
stringclasses
21 values
topic_name
stringlengths
3
135
348b7edd-9d1d-441d-ae44-e05bfe9215de
Most common LMN cause of Facial nerve palsy is?
Trauma
Bell's palsy
Infections
Vascular causes
1b
single
*one of the most common cause of facial weakness is bell's palsy ,a lower motor neuron lesion of the 7th (facial)nerve ,effecting all ages and both sexes *here the lesion is within the facial canal . Ref Harrison20th editionpg 1082-1083
Medicine
C.N.S
25c324ae-9b1e-49b0-b849-3283f8b3a840
Malignant pustule occurs in -
Melanoma
Gas gangrene
Ovarian tumour
Anthrax
3d
single
null
Surgery
null
fce45c6e-0c45-47d5-849a-59bfce0a8b29
a child gets good marks in his exam and his father got a bicycle, he staed to read well, what is the line of therapy
positive reinforcement
negative reinforcement
omission
punishment
0a
single
Behavioral therapy is learning given by BF Skinner , according to him all behaviors are learned phenomenon and thus can be unlearned Positive reinforcement a type of reinforcement when a behavior is rewarded there is more chance that the behavior is repeated Negative reinforcement is that when a behavior is done and an...
Anatomy
Treatment in psychiatry
a4d22a83-6cff-4844-9f46-84234b540d58
The most important action of Secretin is to
neutralize the acid from the stomach
increase secretion of bicarbonates by pancreas
decrease gastric secretion
cause contraction of pyloric sphincter
1b
single
Main Action of Secretin: Secretin increases the secretion of bicarbonate by the duct cells of the pancreas and biliary tract. It thus causes the secretion of a watery, alkaline pancreatic juice (with high content of bicarbonate). Its action on pancreatic duct cells is mediated via cAMP. Secretin causes alkaline pancrea...
Physiology
null
c993142b-7bc3-473a-8327-c9eee155c943
Which is NOT used in treatment of heroin dependence?
Disulfiram
Buprenorphine
Clonidine
Lofexidine
0a
single
Ans. is 'a' i.e., Disulfiram o Heroin is diamorphine and is 3 times more potent than morphine.Treatment of morphine or heroin poisoningo Treatment can be divided into:-A. Treatment of toxicity (overdose)# Overdose is a medical emergency, and is treated with opioid antagonist to reverse the complications (respiratory de...
Social & Preventive Medicine
Mental Health
5136c2e6-9b53-420e-be8e-019cf8a2b078
Aldosterone acts at:
Collecting duct
Glomerulus
Proximal convoluted tubule
Loop of Henle
0a
single
Ans. A Collecting ductRef: Ganong, 23rd ed. pg. 648* Aldosterone is secreted from adrenal cortex.* Action of aldosterone is localized to distal tubule are collecting duct.* Mechanism: Stimulates Na+K+ ATPase at basolateral end which generate gradient for movement of sodium ion from apical membrane causing an increase i...
Physiology
Kidneys and Body Fluids
87563acd-e6a4-4f6f-bf54-cca4adc09e96
DNA enzyme for aging:
Telosomerase
Topoisomerase
Telomerase
DNA polymerase
2c
single
Ans. (c) TelomeraseRef: Harper's Biochemistry, 30th ed. pg. 374, 732, 26th ed. Pg- 318* The ends of each chromosome contain structures called telomeres.* Telomeres consist of short, repeat TG-rich sequences. Human telomeres have a variable number of repeats of the sequence 5'-TTAGGG-3', which can extend for several kil...
Biochemistry
Proteins and Amino Acids
b0559f4d-8376-453e-b88a-39899b6d6fb9
Maternal mortality is maximum in which period –
Antepartum
Peripartum
Postpartum
None
1b
multi
Maternal death mostly occur from the third trimester to the first week after birth. Studies show that mortality risks for mothers are particularly elevated in the first two days after birth.
Social & Preventive Medicine
null
45764e2c-f28d-4abf-a0fe-f9ddab17a398
Cataract blindness is:
Preventable
Curable
Avoidable
Curable and avoidable
1b
single
Ans. Curable
Ophthalmology
null
00cb78d2-a58d-4810-af27-7b1c745ab3b5
Investigation of choice for intramedullary SOL is -
MRI
USG
CT
X-ray
0a
single
Ans. is 'a' i.e., MRI o Investigation of choice for intramedullary space occupy lesion is MRI.
Radiology
Imaging of Musculoskeletal Tumors
e21bbea5-ce59-442e-9058-e7f863190b4f
Daclizumab acts through ?
cGMP activation
Adenylcyclase inhibition
IL 2 receptor blocker
IL10 receptor blocker
2c
single
Ans. is 'c' i.e., IL 2 receptor blocker Monoclonal antibodies (daclizumab and basiliximab) that block the interleukin 2 receptor and are used in prevention of graft rejection as immunosuppresant.
Pharmacology
null
6aac13cd-69c5-468b-a025-8578bf8505d5
Actinomycetoma is caused by-
Actinomyces
Nocardias
Streptomyces
All
3d
multi
Ans. is 'a' i.e., Actinomyces; 'b' i.e., Nocardia; 'c' i.e., Streptomyces
Microbiology
null
305b984e-1c04-487f-8a56-a2280886b4d6
Glycosylated hemoglobin in a normal pregnant lady should be less than:
4.50%
5.50%
6.50%
7.50%
2c
single
The cut off for glycosylated hemoglobin in a pregnant lady is less than 6.5 %.
Gynaecology & Obstetrics
Physiological Changes of Pregnancy
e28691e5-89f4-44b1-a2b1-b95191860d75
'Bird beak' appearance on barium swallow is feature of?
Achalasia cardia
Diffuse esophageal spasm
Caustic stricture
Carcinoma of the esophagus
0a
multi
Ans. A. Achalasia cardia. (Harrison's Medicine, 18th ch. 292; /Fig. 292-5).Achalasia cardia- Megaesophagus/sigmoid esophagus- "Bird beak" deformity- Absence of primary peristalsis below level of cricopharyngeus- Hurst phenomenon (temporary transit through cardia when hydrostatic pressure of barium column is above toxic...
Radiology
G.I.T.
0c94e488-3569-4709-acdf-6225fa2e12d3
Which is the first organ to be affected in left ventricular failure?
Lungs
Liver
Kidney
Brain
0a
single
Ans. (a) LungsRef: Robbin's pathology 9th ed. /529-30* In left ventricular failure, the pooling of blood in lungs will result and will lead to development of pulmonary edema which causes hypoxia and findings of dysnea, orthopnea, pink frothy sputum and death. Hence lungs are immediately affected following LVF.* Subsequ...
Pathology
C.V.S
367cad83-4383-4c47-b2dd-d31fa56115ba
Neurofibromatosis 1 criteria include all except:
Brain tumor
Acoustic neuromas
Dysplasia of the sphenoidal and tibial bone
Cafe-au-lait spots
1b
multi
In Neurofibromatosis 1 (NF1), two or more of the following clinical manifestations are present: Six or more Cafe-au-lait macules Axillary and inguinal freckling Two or more iris Lisch nodules Two or more neurofibromas or 1 plexiform neurofibroma A distinctive osseous lesion such as sphenoidal and tibial dysplasia Optic...
Pediatrics
Genetic and genetic disorders
895b0a22-7c6c-4abc-9bc9-29f257185b1f
In rectus sheath which branch of aoa make anastmosis with superior epigastric aery
Subclan aery
External iliac aery
Internal iliac aery
External carotid A
1b
single
The external iliac aeries are two major aeries which bifurcate off the common iliac aeries anterior to the sacroiliac joint of the pelvis. They proceed anterior and inferior along the medial border of the psoas major muscles. They exit the pelvic girdle posterior and inferior to the inguinal ligament about one third la...
Anatomy
Abdomen and pelvis
87bf0fc4-3501-43a4-80e7-d8d04f6fa7f5
Pain sensations from the ethmoidal sinus are carried by-
Frontal Nerve
Lacrimal Nerve
Nasocilliary Nerve
Infra orbital Nerve
2c
single
As discussed in preceeding text, nasociliary nerve–branch of opthalmic division of trigeminal nerve carries pain sensation from ethmoid sinus.
ENT
null
923384bb-5451-487d-b731-623f9361d295
Conjunctiva epithelium is:
Pseudostratified
Stratified columnar
Stratified non keratinized squamous
Transitional
2c
single
C i.e. Stratified non keratinized epithelium Conjunctival epithelium is stratified non keratinized squamous epitheliumQ. Conjunctiva has palpebral (marginal, tarsal, orbital), bulbar & fornix pas. Marginal palpebral conjunctiva has transitional zone (not epithelium) covered with stratified epithelium with characteristi...
Ophthalmology
null
1154e512-eec5-4eae-b944-3de530532c4e
Which of the following is the national level system that provides annual national as well as state level reliable estimates of fertility and mortality?
Sample registration system
Census
Ad-hoc survey
Sample registration system
0a
single
Sample Registration System (SRS) was initiated in 1964–65 (on a pilot basis; full scale from 1969–70) to provide national as well as state level reliable estimates of fertility and mortality • SRS is a dual record system: Field Investigation: continuous enumeration of births and deaths by an enumerator. Independent ret...
Social & Preventive Medicine
null
d7227e8f-47b5-42b3-9a69-25825f80bc88
How much Potassium is present in the Ringer Lactate solution -
1 mEq/L
4 mEq/L
2 mEq/L
6 mEq/L
1b
single
Ans. is 'b' i.e., 4 mEq/L SolutionVolumebNa+K+Ca2+Mg2+Cl-hco3 (as la- ctate)Dext rose(g/L)mOsm/LExtracellular fluid--14245310327 280-310Lactated ringer's--13043--10928--2730.9% NaCl--154------154----3080.45% NaCl--77------77----154D5W--------------50252D5/0.45% NaCl--77------77--50406D5LR--13043--10928505253% NaCl--513...
Medicine
Fluid & Electrolyte
34bc46b6-1fc9-483d-8a6a-63d5ecb7fc01
Puetz-Jegher syndrome is characterised by
Deafness
Multiple supernumerary teeth
Multiple intestinal polyps
Scleroderma
2c
single
null
Pathology
null
d1e57556-a49c-42d1-b73a-9927f5abe03a
Sex worker with discharging ulcer, gram negative diplococci & growth on modified Thayer main media. Diagnosis ?
N. gonococci
Syphilis
LGV
Chaneroid
0a
single
Ans. is 'a' i.e., N. gonococci Information in this question are ? Gram negative diplococci. Growth on modified Thayer-main media. o Neisseria gonorrhoeae is a gram negative diplococci and Thayer-main medium is the selective medium for gonococci. Lab diagnosis of gonorrhea Urethral discharge is the most impoant specimen...
Skin
null
d5ef9df9-d906-4700-b3ff-baf3bd16d22c
All of the following are true regarding diuretics except:-
Spironolactone is a potassium sparing drug
Mannitol is an osmotic diuretic
Thiazides act by inhibiting sodium-potassium chloride co-transpo
Acetazolamide inhibits carbonic anhydrase enzyme
2c
multi
Name Site of action Example Mechanism Loop diuretics Thick ascending limb of Loop of Henle Furosemide Torsemide Na-K-2Cl sympoer inhibition Carbonic anhydrase inhibitors PCT Acetazolamide Dorzolamide Brinzolamide Carbonic anhydrase inhibition Thiazides DCT Hydrochlohiazide Chlohalidone Na-Cl sympoer inhibition Osmotic ...
Pharmacology
Kidney
4de3ae36-e35c-4bec-ac3c-e83ee383df6e
In case of hypothyroidism which investigation is most informative and most commonly used:
Serum TSH level
Serum T3 and T4 level
Serum calcitonin assay
Serum TRH assay
0a
single
TSH* Most informative among thyroid function test parameters because of ultra-sensitivity* Can detect subclinical hypothyroidism & subclinical hypehyroidism* Hypothyroidism - TSH |* Hypehyroidism - TSH |
Surgery
Thyroid
4c045f3a-6601-4413-92a0-0941d9061a92
. When the confidence level of a testis increased which of the following will happen -
No effect on significance
Previously insignificant value becomes significant
Previously significant value becomes insignificant
No change in hypothesis
1b
single
null
Social & Preventive Medicine
null
43ba8407-9d93-473a-b77b-fda6bd6b667e
Mobile medical care constitutes all except
Primary health care
Secondary health care
Teiary health care
Near home based
2c
multi
Ref:Park's Textbook of Preventive and Social Medicine 25th Ed
Social & Preventive Medicine
Health care of community & international health
601a0006-402b-4565-a117-01981f7db6b4
Monozygotic twins do not have same-
Fingerprints
Genetic make up
Facial appearance
Stature
0a
single
Ans. is "a' i.e., Fingerprints o Monozygotic twins are a result of the division of the single fertilized egg into two embryos. Thus, they have exactly identical DNA, except for the generally undetectable micromutations that begin as soon as the cell starts dividing.o Fingerprints of the identical twins start their deve...
Forensic Medicine
Misc.
4bef8d55-728c-458d-b1b1-030022cf8e02
What is approx fetal weight, if height of uterus is above pubic symphysis is 35 cm and station of head -2?
2.5 kg
3 kg
3.5 kg
4 kg
2c
multi
Ans. is c, i.e. 3.5 kgRef. Dutta Obs. 9/e, p 68Estimation of fetal weight can be done using Johnson formula:If station of head below ischial spine x 155If fetal head is at or above ischial spine- x 155 Here fetal head is at - 2, i.e. above ischial spine, so it will be (35 - 12) x 155 = 3.5 kg.Also Know:USG measurement ...
Gynaecology & Obstetrics
Physiological changes during Pregnancy
66cb240a-b8a0-402c-9a9f-1e0a0ffe3551
A 44-year-old businessman presents to a physician because of a markedly inflammed and painful right great toe. He states that he just returned from a convention, and had noticed increasing pain in his right foot during his flight back home. Physical examination is remarkable for swelling and erythema of the right great...
Allopurinol
Aspirin
Colchicine
Probenecid
2c
multi
The patient has gout, which is due to precipitation of monosodium urate crystals in joint spaces (notably the great toe) and soft tissues (causing tophi, which are often found on the external ears). Colchicine reduces the inflammation caused by the urate crystals by inhibiting leukocyte migration and phagocytosis secon...
Pharmacology
null
697637ad-84e7-46f1-a4d9-7aa5694b36b6
Which of the following is not a feature Eustachian tube in children
Wider and shoer shoer
Flaccid due to less elastin content
Ostmann's pad of fat is more in volume
Isthmus is straight in children
2c
single
The Eustachian tube in children is shoer (16-18mm), wider and more horizontal. It is also less taut due to lack of elastin. The above differences make the infant more prone for retrograde reflux of nasopharyngeal secretions and milk while feeding in supine position. Differences between Infant & adult ET INFANT ET ADULT...
ENT
ENT Q Bank
00200901-085f-4abe-a7ed-b424b0650f1b
Platelet aggregation is blocked by aspirin due to its action on:
Prostacyclin
PGF 2 alpha
Thromboxane A2
Phospholipase C
2c
single
Ans. c. Thromboxane A2 (Ref: Goodman Gilman 12/e p868; Katzung 12/e p638; KDT 7/e p195, 6/e p186, 609)Aspirin causes several different effects in the body, mainly the reduction of inflammation, analgesia, the prevention of clotting, and the reduction of fever. Much of this is believed to be due to decreased production ...
Pharmacology
Antiplatelets and Fibrinolytics
38593373-89e8-4ef5-979a-2062fbb57b9d
Medium used for antibiotic sensitivity:
CLED agar
choclolate agar
Mueller-Hinton agar
Salt milk agar
2c
single
Antibiotic sensitivity testing Antibiotic sensitivity testing is carried out to determine appropriate antibiotic to be used for a paicular strain isolated from clinical specimens. Antibiotic testing can be carried out by two broad methods a) Disc diffusion tests b) Dilution tests REF : ananthanarayana 10th ed
Microbiology
All India exam
5b8cab79-7b05-4d7c-ae03-7c359e2561b1
A person working in an abattoir presented with pustule on hand which turned into ulcer. Which of the following will best help in diagnosis?
Polychrome methylene blue
Carbol fuchsin
Acid fast stain
Calcofluor white
0a
single
Cutaneous anthrax generally occurs on exposed surfaces of the arms or hands. A pruritic papule develops 1-7 days after entry of the organisms and rapidly changes into a necrotic ulcer. The lesion is called a malignant pustule. The anthrax bacillus is Gram positive and nonacid fast. The spores do not stain by ordinary m...
Microbiology
null
b5400f30-922d-44a0-a49b-fefe537ef8c0
Which is the cause of hemolysis in G6-PD deficiency?
Hemoglobin defect
Oxidative stress
Membrane defect
Vitamin B12 deficiency
1b
single
Ans. is 'b' i.e., Oxidative stress * Normally RBCs are protected from oxidant injury by reduced glutathione. Reduced glutathione is generated from oxidized glutathione and the reducing equivalent for this reaction is provided by NADPH. This NADPH is generated in HMP shunt by enzyme Glucose-6-phosphate dehydrogenase, wh...
Pathology
Blood
a6382989-2dd5-420f-b084-cb909bdebb50
Bitemporal hemianopic field defect is characteristic of:
Glaucoma
Optic neuritis
Pituitary tumor
Retinal detachment
2c
single
Ans. is 'c' i.e. Pituitary tumour Bitemporal hemianopia results due to central (sagittal) lesion of the optic chiasma, common causes of which are tumors of the pituitary gland, craniopharyngioma, suprasellar meningioma, glioma of third ventricle, chiasmal arachnoiditis, third ventricular dilatation.Sites of lesion of v...
Ophthalmology
Lesions of the Visual Pathway
b5c834fa-fe93-45bb-8be9-c27f5949365e
A 31-year-old woman has new-onset headaches and blood pressure elevation. She also notices that the symptoms come episodically and consist of palpitations, headache, anxiety, and marked blood pressure elevation. She undergoes a workup for secondary causes of hypertension, and is found to have elevated free catecholamin...
focal myocardial necrosis
proximal aortitis
endothelial plaques
systolic scratchy sound
0a
multi
Focal myocardial necrosis and inflammatory cell infiltration caused by high circulating levels of catecholamines are seen in about 50% of patients who die with pheochromocytoma.Hypertension can further impair left ventricular function.
Medicine
C.V.S.
ff47003f-1c38-4b3f-beab-8c40333fe29e
Macewan's sign is seen in:
Cyanide poisoning
Alcoholism
Lead
Arsenic poison
1b
single
Alcoholism
Forensic Medicine
null
9141d364-5e3d-477a-a94c-c32b09021ebd
Phenol red thread test is used for dry eye. This test-
Requires topical anaesthetic agent
Volume of tears isn't measured as it changes color on contact with tears
If the color changes to blue, it depicts surface mucin deficiency
Requiras pH meter for reading result
1b
single
*Phenol red dye test measures the production of tears without topical anesthesia, as the dye changes its color to red on contact with tears. It doesn't require pH meter for reading the result. Ref: Ophthalmology Yanoff and Duker 4th/e p.277
Ophthalmology
Diseases of orbit, Lids and lacrimal apparatus
11963486-0df3-4674-a7bd-6f2eefefb911
Vallecula sign is seen in
TB laryngitis
Vocal nodule
Inveed papilloma
Acute epiglottitis
3d
multi
Depressing the tongue with a tongue depressor may show red and swollen epiglottis. Indirect laryngoscopy may show oedema and congestion of supraglottic structure. This examination is avoided for fear of precipitating complete obstruction. It is better done in the operation theatre where facilities for intubation are av...
ENT
Larynx
5333eaa6-744a-45de-a1ff-a03c87ffd2e0
Devic's disease is associated with
Aquaporin 0
Aquaporin 1
Aquaporin 2
Aquaporin 4
3d
single
(D) Aquaporin 4 # NEUROMYELITIS OPTICA (NMO) or Devic's disease or Devic's syndrome, is a heterogeneous condition consisting of recurrent and simultaneous inflammation and demyelination of the optic nerve (optic neuritis) and the spinal cord (myelitis).> Currently at least two different causes are proposed based on the...
Medicine
Miscellaneous
1cb58d15-0761-494f-82c4-5d3ea5485394
Melanin is formed from which aminoacid?
Phenylalanine
Tyrosine
Tryptophan
Histidine
1b
single
Ans. is 'b' i.e., TyrosineAmino acidsBiological important compoundTyrosineCatecholamines (epinephrine, norepinephrine, dopamine), thyroxine, triiodothryonine, melanin.(Note : - Phenylalanine is the precursor of tyrosine, thus it can also give rise to all these compounds through tyrosine (phenylalanine - Tyrosine - Cate...
Biochemistry
Proteins and Amino Acids
adf4e294-ea7d-4df6-9676-fc73cb6aa80c
An obese 50-year-old woman undergoes a laparoscopic cholecystectomy. In the recovery room she is found to be hypotensive and tachycardic. Her arterial blood gases reveal a pH of 7.29, partial pressure of oxygen of 60 kPa, and partial pressure of CO2 of 54 kPa. The most likely cause of this woman's problem is
Acute pulmonary embolism
CO2 absorption from induced pneumoperitoneum
Alveolar hypoventilation
Pulmonary edema
2c
single
Because of the ease with which carbon dioxide diffuses across the alveolar membranes, the PaCO2 is a highly reliable indicator of alveolar ventilation. In this postoperative patient with respiratory acidosis and hypoxemia, the hypercarbia is diagnostic of alveolar hypoventilation. Acute hypoxemia can occur with pulmona...
Surgery
Miscellaneous
e9c01c78-667b-46a7-be31-449a6024d8e4
During intraoperative period following capnograph waveform is seen. What does it signify.
Return of spontaneous ventilation
Airway obstruction
Hyperventilation
Oesophageal intubation
0a
single
Above ETCO2 curve depictsSpontaneous effos It signifies return of spontaneous ventilation and the patient is coming out of the anaesthesia The cleft is K/ACURARE CLEFT Repeat a dose of neuromuscular blocker if you want to maintain the muscle paralysis ??"Malignant hypehermia:Progressive rise in ETCO2 ??"Bronchospasm:Sh...
Anaesthesia
NEET Jan 2020
a6bcc7af-bcc3-47d6-ab56-14f8d45293e1
A 3 year old child presents with a history of repeated sinopulmonary infections caused by encapsulated organisms. Which of the following is most likely to be deficient in this case?
IgG4
IgG3
IgG2
IgG1
2c
single
Deficiency of IgG2 results in recurrent sinopulmonary infections with encapsulated organisms. Deficiency of IgG1 - Bacterial infections (Diptheria, tetanus) Deficiency of IgG3 - Viral infections Deficiency of IgG4 - Parasitic infections IgG is the only maternal immunoglobulin that is normally transpoed across the place...
Microbiology
Immunology
798fd268-a21d-4847-8b6e-cac0e9626903
Glucose transpo occur with the help of following ion in absorption in gut region
Na+
K+
Ca+
CI-
0a
single
Glucose is absorbed into the epithelial cells lining the mucous membrane of the small intestine from their brush border surface by an active transpo mechanism Sodium co-transpo mechanism. Binding of glucose & Na+ to carrier protein: The carrier protein in cell membrane has 2 binding sites, one for sodium & another for ...
Physiology
G.I.T
5b9ecb2f-6f18-4c46-a892-e5cc729a37ae
Thomas splint most troubling is:
Ring
Side bars
Gauze support
Traction attachment
0a
single
(a) Ringbecause it impinges against proximal thigh.
Orthopaedics
Management In Orthopedics
c38cd2b7-8740-4c4b-87c7-31c3689e8a13
Aziththromyan prophylaxis in trachoma is given when prevalence is above?
8%
6%
4%
10%
3d
multi
<p> Current WHO recommendations for antibiotic treatment of trachoma District level prevalence is >10% in 1-9 years old children: mass treatment with azythromycin Reference:WHO Trachoma control:A guide for programme managers,2006;page no:21-22. <\p>
Social & Preventive Medicine
Communicable diseases
6839663b-84df-4318-aaef-99078a1ee7b7
Does not include in strand field's "seven I" principles of health education
Identification
Involvement
Implementation
Innovation
2c
single
"SEVEN I" principle of strandfield : Identification. Indigenization. Involvement. Indoctrination. Integration. Influencess. Innovation.
Social & Preventive Medicine
null
1800615f-870d-430c-9e8f-330e870e5f9b
Mechanism of action of ciprofloxacin in gram negative bacteria:-
Inhibition of mycolic acid
Inhibition of topoisomerase IV
Inhibition of DNA gyrase
Inhibition of helicase
2c
single
MECHANISM OF FLUOROQUINOLONES (FQ) In gram negative bacteria, FQ inhibit DNA gyrase by binding to its A subunit and interfere with cutting and resealing function. In gram positive bacteria, FQ inhibit similar enzyme DNA topoisomerase IV.
Pharmacology
Antimetabolites and Quinolones
680f2013-cc37-43f2-9d1f-60c946249a06
Most common tumor to extend from intracranial to orbit is –
Astrocytoma
Pituitary adenoma
Craniopharyngioma
Sphenoidal wing meningioma
3d
single
"Meningiomas are the most common intracranial tumor to extend to the orbit".......... Ophthalmic oncology Meningiomas commonly arise from the dura of sphenoid wing, i.e. sphenoid wing meningioma.
Ophthalmology
null
d6579434-b7f0-4e26-b8d1-d3ea5dcc2af4
What is the generation time of Mycobacterium leprae?
2-5 days
7-10 days
12-14 days
20-25 days
2c
single
Generation time of bacteria refers to the doubling time. Mycobacterium leprae is the slowest growing human bacterial pathogen, it has a doubling time of 14 days. It grows best at 30 degree C, at a temperature lower than body temperature, therefore it grows preferentially in the skin and superficial nerves. Mycobacteriu...
Microbiology
null
3b95c99d-e512-42cb-a6ca-6e100513fa60
A 35 year old male presents to the urologist for an infeility evaluation. A biopsy of his testis is performed to check sperm production and maturation. A microscopic section reveals only a few germ cells near the basal lamina in the seminiferous tubule. Which of the following cells is the germ cell closest to the basal...
Primary spermatocyte
Secondary spermatocyte
Spermatid
Spermatogonia
3d
single
Maturation of germ cells (spermatogenesis) within the seminiferous tubules occurs in a concentric pattern with the less mature spermatogonia near the basal lamina and the mature forms near the tubule center. Spermatogonia are 2N cells and mature into larger primary spermatocytes (4N) . These mature into secondary sperm...
Anatomy
null
a227a262-f152-49e8-a5ea-cde7ea09eb7c
A child has mid-crown fracture in a permanent maxillary central incisor several months ago, the pulp is now necrotic, radiographic examination reveals an incompletely formed root with an open apex. The treatment of choice is:
Formocresol pulpotomy
Root canal therapy
Calcium hydroxide pulpotomy
Apexification
3d
single
Apexification is the process of inducing the development of the root and the apical closure in an immature pulpless tooth with an open apex. The main aim of apexification is to preserve the Hertwig’s root sheath and apical pulp tissue. Ref: Textbook of endodontics, Nisha Garg and Amit Garg, 3rd edition, pg no:548
Dental
null
07524d17-bbf3-46d5-a5dc-97443d76615f
In Chronic Viral Hepatitis:
Hepatitis A virus infection is a common cause inchildren
Morphological classification into Chronic ActiveHepatitis and Chronic Persistent Hepatitis areimpoant
Fatty change is pathognomic of Hepatitis C virusinfection
Grading refers to the extent of necrosis andinflammations
3d
single
. Grading refers to the extent of necrosis andinflammations
Pathology
null
fe2903f5-7f35-48e5-8d8a-210380d3a1ac
The double decidual sac sign (DDSS) is the best method for ultrasound diagnosis of
Monoamniotic Dichorionic twins
Diamniotic dichorionic twins
Ectopic pregnancy
Normal pregnancy
3d
single
Double decidual sac sign on USG - Intra-uterine sac (Eccentrically placed) Outer layer - Decidua Parietalis Inner layer - Decidua Capsularis Indicates - Intrauterine pregnancy Intradecidual ring sign is the first sign of pregnancy on USG.
Gynaecology & Obstetrics
Diagnosis of Pregnancy
0ab71438-2c93-4072-be93-71b19735ca5f
Which of the following predisposes to placenta previa?
Primigravida
Singleton pregnancy
Diabetesmellitus
Past cesarean pregnancy
3d
single
Ans: D
Unknown
null
9cdda262-5a54-43a9-8943-ba05d492aeae
All are true regarding Crohn's disease except:
Infertility
Risk of Ca
Medical treatment includes antibiotics, probiotics and TNF alpha blockers
ASCA-negative
3d
multi
Ref: Harrison s Principles of Internal Medicine, 18th edition, pg 2486 Explanation: Crohn's disease- MC site-terminal ileum with rectal sparing, skip areas + It is transmural, hence more of fistula formation More of systemic symptoms, pain, abdominal mass Toxic megacolon - Perforation Intraabdominal abscess, fallopian ...
Unknown
null
ea220936-f61f-4209-88f8-ff6605ae001a
Nucleic acids absorb UV light maximally at the wavelength of
260nm
280 nm
410 nm
320 nm
0a
multi
Nucleic acids absorb UV light maximally at the wavelength of 260 nm 260/280 ratio of pure DNA/RNA is in the range of 1.8 to 2. Amino acids absorb U.V light (not visible light)- colorless. Aromatic amino acids absorb U.V light at 250-290 nm (maximum absorption is at 280nm) because of conjugated double bonds.
Biochemistry
Basics of DNA
97b5d816-45b0-4f12-9d89-53fdd1a428b7
Children born to mothers with systemic lupus erythematosus are likely to have one of the following anomalies:
Atrial septal defect
Tetralogy of Fallot
Transposition of great vessels
Complete heart block
3d
multi
d. Complete heart block(Ref: Nelson's 20/e p 2171-2174, Ghai 8/e p 457-461)Congenital complete AV blockIt is presumed to be caused by autoimmune injury of fetal conduction system by maternally derived anti-SSA/Ro, anti-SSB/ La antibodies in a mother with systemic lupus erythematosus (SLE) or Sjogren syndromeAutoimmune ...
Pediatrics
C.V.S.
eb7d4add-7ed3-407e-88c3-bf2d73e189a0
All of the following cause hyperventilation except
Decreased pH in CSF
Decreased plasma HCO3
CO poisoning
Increased adrenergic levels
2c
multi
Arterial hypoxemia is defined as an arterial P02 (partial pressure of oxygen) less than 80 mmHg, who is breathing room air at sea level. And because the partial pressure of a gas is determined by the soluble fraction of gas and not by the amount carried chemically bound to hemoglobin - the Hb does not determine P02 and...
Physiology
null
1a502be3-9afb-4584-b64b-f3785bda98c2
Stem cells are present where in cornea -
Limbus
Stroma
Epithelium
Descmet's membrane
0a
single
Answer- A. LimbusLimbal stem cells (also called corneal epithelial stem cells) are stem cells located in the basal epithelial layer of the corneal limbus.Proliferation of limbal stem cells maintains the cornea; for example, replacing cells that are lost tears.Limbal stem cells also prevent the conjunctivalepithelial ce...
Ophthalmology
null
621c72a0-b1e7-49ee-bef6-9f7819cbbf81
A child brought to casualty with reports of violent shaking by parents. The most likely injury is?
Long bone fracture
Ruptured spleen
Subdural haematoma
Skull bone fracture
2c
single
Violent shaking (by parent) may cause subdural hematoma; whereas ruptured spleen occurs due to compression of abdomen; long bone fracture due to compression, bending, direct blow, pulling and twisting; and skull fractures due to direct blow. Caffey (1974) described the effects of shaking as a major cause of subdural ha...
Forensic Medicine
null
c88c37ec-d513-4006-8bfc-bc12b0f09a46
Collagen biosynthesis occurs inside the:
Chondroblasts
Odontoblasts
Osteoblasts
Fibroblasts
3d
single
null
Dental
null
cdee62b1-9326-4bfb-80e8-3761ed6ff45d
About chi-square test, true is
Less no. of samples are associated with less error
<0.001 is statistically significant
Categories of data used in test need not be mutually exclusive and discrete
Tests correlation and regression
1b
multi
null
Social & Preventive Medicine
null
c86f8ca5-1e1d-4ed7-9a13-efbaa16c4073
"Inflation of lungs induces fuher inflation" this is explained by
Hering-Breuer inflation reflex
Hering-Breuer deflation reflex
Head's paradoxical reflex
J-reflex
2c
single
Head's paradoxical reflex is paradoxical to Hering- Breuer inflation reflex This reflex might be the cause for inflation of the lungs in the newborn when the newborn takes the first breath
Physiology
Nervous system
0b14eff2-2d49-4880-b141-d6e9e96f27aa
Most common cause of Acute Aseptic Meningitis in children is
Arbovirus
Respiratory syncytial virus
Enterovirus
Herpes family
2c
single
(C) Enterovirus # VIRAL CAUSES INCLUDE THE FOLLOWING: Enteroviruses - coxsackievirus, echovirus, poliovirus. Herpes simplex virus (HSV) types 1 and 2 (HSV-1, HSV-2) Varicella-zoster virus. Arboviruses, Epstein-Barr virus, HIV, Influenza virus types A and B, Mumps virus.> Many different viruses can cause meningitis.> Ab...
Pediatrics
Miscellaneous
e0992ffa-0b1a-497f-9563-cd88bf5c8fd8
Reids index is increased in: March 2007
Bronchial asthma
Bronchiectasis
Chronic bronchitis
Pneumonia
2c
single
Ans. C: Chronic bronchitisThe Reid Index is a mathematical relationship that exists in a human bronchus section observed under the microscope. It is defined as ratio between the thickness of the submucosal mucus secreting glands and the thickness between the epithelium and cailage that covers the bronchi.It isn't of di...
Pathology
null
f5c442b4-0128-4b74-bf36-078a2dc00dd6
In psychoanalytic terms, obsessive-compulsive disorder is fixed at -
Oedipal stage
Genital stage
Oral stage
Anal stage
3d
single
OCD results from a regression from the oedipal phase to anal phase of psychosexual development, i.e. In OCD fixation occurs in anal stage (Note - Regression is reversion from higher level of development to lower level of development).
Psychiatry
null
eeaa0443-e294-4e6c-a749-f4b10c9e097b
Subconjunctival cyst is seen in?
Toxoplasmosis
Cysticercosis
Leishmaniasis
Chaga's disease
1b
single
Ans. is b i.e., Cysticercosis Parasitic cysts occurs in subconjunctival cysticercus, hydatid cyst and filarial cyst.
Ophthalmology
null
724a08bc-cc4d-4ad0-b866-84a8082c4c52
"Antihistone" antibodies are detectable in:
CREST
PAN
Drug induced Lupus
Intestinal lymphoma
2c
single
Drug induced Lupus
Pathology
null
8fe5f498-31ce-49b4-869e-5ccca4178377
The best method of teaching an urban slum about ORS is -
Lecture
Role play
Demonstration
Flash card
2c
single
A demonstration is a carefully prepared presentation to show how to perform a skill or procedure.Here a procedure is carried out step by step before an audience or the target group,the demonstrator asceaining that the audience understands how to perform it (refer pgno:864 park 23 rd edition)
Social & Preventive Medicine
Health education & planning
33955184-e6fd-469e-b3ab-026e1a13689a
Tardy ulnar nerve palsy occur as a delayed sequele of
Supracondylar fracture of humerus
Posterior dislocation of elbow
Fracture of lateral condyle of humerus in children
Fracture of Olecranon
2c
single
C i.e. Fracture lateral condyle humerus
Surgery
null
d72567e2-443d-4a05-83f8-96dee6a80ba3
High anticholinergic propey is present in the following antihistaminic agent
Astemizole
Diphenhydramine
Terfenadine
Fexofenadine
1b
single
null
Pharmacology
Autacoids
c62a6fd2-33de-483f-9bb3-b506460af945
Characterstic X Ray finding in ASD is:
Enlarged left ventricle
Enlarged left atria
Pulmonary pletheora
PAH
2c
single
C i.e. Pulmonary plethora
Radiology
null
34baa828-5634-4733-8f1b-ba26d21af367
Pain relief in chronic pancreatitis can be obtained by destruction of
Celiac ganglia
Vagus nerve
Anterolateral column of spinal cord
None of the above
0a
multi
Chronic pancreatitis Pain from the pancreas is carried in sympathetic fibres that traverse the Celiac ganglion, reach the sympathetic chain through the splanchnic nerves, and then ascend to the coex Celiac plexus nerve blocks performed either percutaneously or endoscopically have been employed to abolish this pain with...
Anatomy
G.I.T
fb22b8a3-0ae1-4256-bb37-2775f69b1b05
All are true about peritoneal folds except
Median umbilical fold is obliterated to become urachus in adults
Medial umbilical fold is peritoneal fold on medial umbilical ligament
Medial umbilical fold covers allantois
Lateral umbilical fold produced by inferior epigastric vessels
2c
multi
Urachus fistula is a remnant of allantoic diveiculum. It is a diveiculum of hind gut and connects umbilicus to urinary bladder. The lumen of allantoic duct-is obliterated at the time of bih. Median Umblical Ligament is the remanant of urachus. It covers allantois. Urine keeps on dribbling in urachal fistula Figure show...
Anatomy
Umblicial cord and diaphragm
d1903ef7-2844-4458-8f31-b76ef4484238
The principal characteristics of attention-deficit/hyperactivity disorder are all of the following except one. Which one is the exception?
Inattention
Mental retardation
Hyperactivity
Impulsivity
1b
multi
Inattention and hyperactivity/impulsivity are the key behaviors of ADHD. Some people with ADHD only have problems with one of the behaviors, while others have both inattention and hyperactivity-impulsivity. Most children have the combined type of ADHD. In preschool, the most common ADHD symptom is hyperactivity. It is ...
Dental
null
8dce65c5-b95d-4d53-a1d5-b74cb48d4464
21st tooth erupts at:-
6 years
8 years
10 years
12 years
0a
single
Eruption is defined as the superior pa of crown of the tooth appearing level with the surface of the alveolar bone.Temporary dentition: total 20 number of teeth, stas at 6 months till 2 years.Permanent dentition: total 32 number of teeth, stas at 6 years completed by 17 - 25 years.1st to erupt is molar 1 (M1) and last ...
Forensic Medicine
FMGE 2017
3e71a440-f571-458d-b879-007d265e51fb
Most common viral cause of Fulminant hepatic failure in pregnancy?
HAV
HBV
HCV
HEV
3d
single
HEV- increases risk of fulminant hepatic failure in pregnancy
Medicine
Hepatitis
cf7902f7-2a01-458c-ae6c-4b7ddf126c00
True about diabetic nephropathy -
Microalbuminiuria is not an indicator of long term cardiovascular morbidity.
Strict glycemic control cannot prevent microalbuminuria
b-islet cell\/pancreatic transplantation can improve the proteinuria in early stage.
Angiotensin receptor blockers have no additive advantage over other drugs except B.P. control.
2c
multi
Beta islet cell/ pancreatic transplantation can improve proteinuria in early stages.. Strict control of blood glucose retards the progression of any diabetes related complication Early pathological change and albumin excretion abnormalities is reversible with normalization of plasma glucose Administration of ACE inhibi...
Medicine
Endocrinology
e0d722cf-e57d-4ad1-b61b-619d77c4cdeb
Which of the following is an adrenergic drug preferred for arresting labour?
Ritodrine
Isoprenaline
Salbutamol
Terbutaline
0a
single
(Ref: KDT 6/e p323) Isoxsuprine and ritodrine are selective b2 agonists useful as tocolytic agents for arresting labour. Pulmonary edema is an impoant adverse effect of these agents.
Anatomy
Other topics and Adverse effects
440222b4-4c23-4ae3-b28d-a513db91dbfc
Sixth cranial nerve palsy causes of left eye causes?
Accomodation paresis in left gaze
Ptosis of left eye
Adduction weakness of left eye
Diplopia in left gaze
3d
single
Ans. is 'd' i.e., Diplopia in left gaze o Sixth nerve supplies lateral rectus, therefore its palsy results in abduction weakness (not adduction weakness)o In left gaze, there is abduction of left eye and adduction of right eye. If there is paralysis of lateral rectus of left eye (6th nerve paralysis), abduction of left...
Ophthalmology
Ocular Motility
ee16afe4-8042-451b-bcc8-b12f0dcf583d
Father of modern toxicology -
Paracelsus
Galton
Orfila
Guftason
2c
single
orfila is known as father of modern toxicology Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr PC IGNATIUS THIRD EDITION PAGE 397
Forensic Medicine
Poisoning
0240af15-bef8-4d4f-9e80-d8acdeb4d049
5-year-old male brought to casualty by his mother because of episode of sudden vomiting. He has been behaving strangely according to mother. Laboratory findings showed microcytic hypochromic anemia with the above finding. The most probable poisoning is:
Chronic arsenic poisoning
Chronic lead poisoning
Chronic mercury poisoning
Chronic copper poisoning
1b
multi
Ans. (B). Chronic lead poisoningThe above blood picture shows basophilic stippling of RBCs.Basophilic stippling (dots in the red blood cells) is due to the inhibition of 5 pyrimidine nucleotidase enzyme resulting in aggregation of ribosomes.Other findings in blood: Microcytic hypochromic anemia, anisocytosis, poikilocy...
Forensic Medicine
Forensic Toxicology - Concepts, Statutes, Evidence, and Techniques
e9e0492a-afd8-4bd8-9d51-1d34aa7f6564
Submandibular gland is crossed by which nerve?
Lingual
Hypoglossal
Glossopharyngeal
Facial nerve
3d
single
Submandibular duct is thin-walled and is about 5 cm long.it emerges at the anterior end of the deep pa of the gland and runs forwards on the hyoglossus between the lingual and hypoglossal nerves.at the anterior border of the hyoglossus, the duct is crossed by lingual nerve.it opens on the floor of the mouth on the summ...
Anatomy
Head and neck
05655bd8-0b6d-4982-b2e1-d0cb1f62c67a
Ramesh 40 yrs male patient presenting with polyuria, pain abdomen, nausea, vomitting, altered sensorium was found to have bronchogenic carcinoma. The electrolyte abnormality seen in him would be -
Hypokalemia
Hyperkalemia
Hypocalcaemia
Hypercalcemia
3d
single
null
Medicine
null
d8dbbc3c-5165-4455-9bc4-9b39c2e0d88c
Folic acid metabolism is inhibited by : a) Sulfonamides b) Methotrexate c) Nitrous oxide d) Trimethoprim e) 5–Flucytosine
acd
abd
bde
ace
1b
single
null
Pharmacology
null
edc8bc6a-0a6a-43e2-8e6c-71b46979e3c9
Patient with fixed dilated pupil, with iris atrophy and secondary glaucoma after penetrating keratoplasty is suggestive of:
Benedict's syndrome
Posner-Shlossman syndrome
Kaufmann's syndrome
Urrets Zavalia syndrome
3d
single
Ans. d. Urrets Zavalia syndrome (Ref: style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif">icles/PMC1770988)A fixed dilated pupil following penetrating keratoplasty is a well recognized if rare postoperative complication.The mydriasis following penetrating keratoplasty was first described b...
Ophthalmology
Secondary Glaucomas
f9654c2f-0bf8-4abf-9ae9-8c8fa439fc64
Treatment of acute asthma include all except-
Prednisolone
Salbutamol
Salmeterol
Ipratropium bromide
2c
multi
Ans. is 'c' i.e., Salmeterol o Long acting Beta - 2 agonists have no role in acute attack of asthma. They are useful in persistent asthma.
Pharmacology
null
bceeefc3-dad5-4457-9a96-1a804093b44c
Characteristic visual field defect in optic chiasma lesion -
Homonymous hemianopia
Bitemporal hemianopia
Upper quadrantanopia
Lower quadrantanopia
1b
single
Ans, is 'b' i.e,. Bitemporal hemianopia Site of lesionVisual field defectOptic nerveBlindnessOptic cbiasmaBitemporal hemianopiaOptic tractIncongruent homonymous hemianopiaLateral geniculate bodyHomonymous hemianopiaOptic radiation (Total)Homonymous hemianopia, sometimes with macular sparingOptic radiation lower fibres ...
Ophthalmology
Lesions of the Visual Pathway
ec109e50-48ad-4255-aa36-5cc9cbbfc1f2
A volunteer Ram will receive a new drug in a phase I clinical trial. The clearance and the volume of distribution of the drug in Ram are 1.386 I/hr and 80 L respectively. The half life of the drug in him would be approximately:
83 hr
77 hr
40 hr
0.02 hr
2c
single
null
Pharmacology
null
7f1d29a1-ae76-4c51-80bf-4c6f462bce5f
Hand over mouth technique was first described by:
Dr. Evangeline Jordan
Addeston and Gold fried
Dr.G.V.Black
Dr. Goldman
0a
single
null
Dental
null
dace2337-3e05-40f4-8e5f-0c957dc6d9de
Most common cause of spontaneous sub-arachnoid haemorrhage is -
Trauma
Hypertension
Berry aneurysm rupture
Raised intracranial tension
2c
single
null
Medicine
null
0deceed6-5c74-4689-b838-55df0b2aebc6
Ehrlich's test is done to detect:
Urinary amylase
Urinary cystine
Abnormal porphyrin
Urobilinogen
3d
single
D Harper, 26th ed, p. 283 & 25th ed, p. 370
Biochemistry
Miscellaneous (Bio-Chemistry)
79cfa9cd-3cb9-4bf5-822a-1b764a773dc2
B cell prolymphocytic leukemia patients differ from those with B cell chronic lymphocytic leukemia in
Presenting at a younger age
Having a lower total leucocyte count
Having prominent lymphadenopathy
Having a shorter survival
3d
single
null
Medicine
null
2c79193f-6b10-43a7-af7c-865cdba91dd6
Millenium development goals formulated in 2000 were to be achieved by -
2005
2015
2010
2020
1b
single
- During September 2000, representatives of 189 countries met at Millennium Summit in New York to adopt United nations Millennium Declaration. - the goals in the area of development and povey eradication are now referred as Millennium Development Goals. - Governments have set date of 2015 by which they would meet the M...
Social & Preventive Medicine
Health education & planning
89857ee9-3093-4da8-b3f9-fa8a8d0eb60a
In the stage of Grey hepatization-
WBC's fill the alveoli
RBC's fill the alveoli
Organisms fill the alveoli
Accumulation of fibrin
3d
single
Ref:Textbook of pathology (Harsh mohan)6th edition,page no. 469 GREY HEPATISATION: LATE CONSOLIDATION This phase lasts for 4 to 8 days Grossly, the affected lobe is firm and heavy. The cut surface is dry, granular and grey in appearance with liverlike consistency .The change in colour from red to grey begins at the hil...
Pathology
Respiratory system
55aa1e36-f63c-47c1-aacf-30683e406d05
Twin pregnancy, but due to two different men is called: NEET 14
Superfetation
Superfecundation
Both of the above
None
1b
multi
Ans. Superfecundation
Forensic Medicine
null
60994797-e56d-4059-9a33-5d982e45d9e2
Low bih weight baby is defined as baby weighing: September 2006
1000 gm
1500 gm
2000 gm
2500 gm
3d
single
Ans. D: 2500 gm Low bih weight (LBW) is defined as a fetus that weighs less than 2500 g (5 lb 8 oz) regardless of gestational age. Other definitions include Very Low Bih Weight (VLBW) which is less than 1500 g, and Extremely Low Bih Weight (ELBW) which is less than 1000 g. Normal Weight at term delivery is 2500 g - 420...
Gynaecology & Obstetrics
null