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135
0e7a0c23-2b0e-4137-a985-bcd54b43f464
A patient presents with cervical lymphadenopathy. Biopsy demonstrates a nodular lymphoma with follicle formation. This lesion would most likely be associated with which of the following?
bcr-abl hybrid
bcl-2 activation
c-myc activation
t(8, 14)
1b
single
Nodular lymphomas of all types are derived from the B-cell line. The translocation t(14, 18), with bcl-2 activation, is associated with these lymphomas. Must know: An abl-bcr hybrid and t(9, 22) translocation are associated with chronic myeloid leukemia (CML). c-myc activation and t(8, 14) are associated with Burkitt's...
Pathology
null
2133621d-fc12-4f00-90d4-66c9c6323c8c
Regarding anaplastic carcinoma, which of the following statement is true?
Common in young
Associated with p53 mutation
Surrounding neck tissue is usually free
Radiotherapy cures
1b
multi
ATC is the most aggressive form of thyroid carcinoma with a disease-specific moality approaching 100%. A typical manifestation is an older patient with dysphagia, cervical tenderness, and a painful, rapidly enlarging neck mass. Patients frequently have a history of prior or coexistent DTC, and up to 50% have a history ...
Surgery
Endocrinology and breast
4145bc69-f09b-44b0-a586-939f44d620a3
ESI act was made in -
1946
1948
1952
1954
1b
single
- the ESI act passed in 1948 is an impoant measure of social security and health insurance in the country. - it provides for ceain cash and medical benefits to industrial employees in case of sickness, maternity and employment injury. Reference : Park's textbook of preventive and social medicine, 23rd edition, pg no: 8...
Social & Preventive Medicine
Hospital waste and disaster management, Occupational health
a76e61bf-90b3-4278-a3b4-88ae80648880
Munchausen's syndrome by proxy involves-
Drug abuse
Toxin-mediated neuropsychiatric
Illness caused by care giver
All of the above
2c
multi
Munchausen's syndrome by proxy is a form of child abuse in which a patent, usually the mother, or a caretaker repeatedly fabricates or actually inflicts injury or illness in a child for whom medical intervention is then sought, often in an emergency setting.
Psychiatry
null
b36c4dfb-3fab-40a1-b341-81ff1c1167a3
All of the following are features of phaeochromocytoma except :
Hypeensive paroxysm
Headache
Ohostatic hypotension
Wheezing
3d
multi
Answer is D (Wheezing): Wheezing has not been mentioned as a symptom of Pheochromocytoma. The most common symptoms in order of frequency during paroxysm are: - Headache - Palpitation - Vomiting - Sweating - Dyspnea - Weakness - Pallor The most common manifestation is hypeension. e It most commonly occurs in paroxysms i...
Medicine
null
4f0d57d3-1ead-4648-b574-1a52247a4b25
MC malignancy in children is:
Retinoblastoma
Leukemia
Wilms tumor
Neuroblastoma
1b
single
b. Leukemia(Ref: Nelson 20/e p 2416)Most frequent childhood cancers are: (in order of decreasing frequency)Leukemia (Most common is ALL)Brain TumorsNeuroblastomaWilms tumor
Pediatrics
C.V.S.
49407639-b13e-4b60-b70e-4f26aa3ceeb1
In a 10-year-old child the lower canines are trying to erupt in 2mm insufficient space. The primary molars are large and firmly fixed. The 1st premolars are also erupting. The treatment of choice is:
Remove primary 2nd molars
Place a removable bite-opener
Remove 1st premolars
Mesial stripping of primary 2nd molars
3d
single
null
Dental
null
5cb29ecf-479a-4d05-a96d-7ab9b09e3e44
Isthmus of thyroid gland lies at which level -
C2
C4
C5
C7
3d
single
Ans. is 'd' i.e., C7 Scheme to show the location arsd subdivisions of the thyroid gland including the false capsule
Anatomy
Thyroid Gland
12019185-33e2-4f7d-a34a-840a28c49628
Which of the following side effects are seen with etomidate-
Myoclonus, Adrenal suppression, Haemodynomic imbalance(HI)
Myoclonus, adrenal suppression, pain on IV injection
Pain on IV injection, Adrenal suppression, HI
Pain on IV injection, HI ,Myoclonus.
1b
single
Etomidate a intravenous anaesthetic agent is Milky white in colour , imidazolone derivative, causes pain on iv injection. Major advantages over other intravenous agents is cardiovascular stability thus use cardiac compromised patients Routinely not in clinical use since it is adrenal suppressant. Other side effects myo...
Anaesthesia
Intravenous Anesthetic Agents
3aeea2d0-4027-46a6-8e90-0c3da0d3b67a
Which of the following nerves lies closest to the Wharton' s duct -
Hypoglossal
Lingual
Chorda tympani
Facial
1b
single
null
Surgery
null
46477482-c4d2-4f7f-84a5-951bdb858606
Which carrier pump is transpoing solutes in thick ascending limb of Henle loop?
Carrier pump Na-K-2Cl transpoer.
NaCl- cotranspoer
Na2+-H+ exchanger
Na2+-K+ exchanger
0a
single
Carrier pump Na-K-2Cl transpoer. REABSORPTION IN THICK ASCENDING LIMB: Sodium, Potassium & Chloride reabsorption: By "Secondary active transpo" - Through Na2+-K+-2Cl-- carrier transpoer. Transpos one Na2+, one K+, & two Cl-. Active sodium absorption occurs. 30% filtered Na2+ reabsorbed. Ref: Guyton 12th Ed.
Physiology
All India exam
29d06fef-7501-4acc-97fb-319d93785589
Function of incretin is -
Increased heart rate
Increased insulin secretion
Increased respiratory rate
Stimulate erythropoiesis
1b
single
Ans. is 'b' i.e., Increased insulin secretion o Incretins are GI hormones which are secreted by enteroendocrine cells in response to meals.o The most important action of incretins is to stimulate insulin secretion after a meal.o Two important GI incretins are.i) Glucagon-like peptide 1 (GLP-1).ii) Glucose-dependent ins...
Physiology
Pancreas
c2b16fd2-fc07-4a6f-9efc-07386c851f78
Cribriform, Honey comb (or) swiss cheese histology pattern is seen in
Adenoid cystic carcinoma
Pleomorphic adenoma
Acinic cell carcinoma
Clear cell carcinoma
0a
single
null
Pathology
null
85ade234-0532-415b-8520-0a21a377d771
Which of the following malignancy is associated with underlying progression and spreads characteristically in a stepwise fashion and hence staging the disease is an impoant prognostic factor? -
Hodgkin's lymphoma
Multiple myeloma
Mature T cell NHL
Mature B cell NHL
0a
multi
Hodgkin&;s disease primary arises within the lymph nodes and involves the extranodal sites secondarily Based on the extent of involvement of the disease ,Staging is studied in order to select proper treatment and assess the prognosis. Reference textbook of Pathology 6th edition author: Harsha Mohan page number 369-373
Pathology
Haematology
0744f560-f170-40b8-a9fb-4931ed0f1371
A patient presented with defective adduction of the hip joint with pain in the knee and hip joint, the nerve involved is?
Obturator nerve
Tibial nerve
Femoral nerve
Saphenous nerve
0a
single
Obturator nerve is the largest nerve formed from the anterior divisions of lumbar plexus (L2,L3,L4).The roots unite within the posterior pa of psoas, and then descends through psoas and runs downward over sacral ala into lesser pelvis, lying lateral to ureter and internal iliac vessels. They enter the upper pa of the o...
Anatomy
null
f3284c27-b880-49a7-8e57-b9867e7e64be
In paogram, first time of the initial markings are made in:
Left side of the action line
On the action line
On the ale line
Right side of the ale line
2c
single
Paograph In paogram, first time of the initial markings are marked on the ale line. The subsequent plotting is done from this point. Till the graph stays on the left if the ale line, the progress can be considered satisfactory. If the graph moves towards the right of the ale line, caution is required and when the graph...
Gynaecology & Obstetrics
Obstetrics
63350a10-8aa9-42c8-a742-5366dce5eaa9
Corpulence index is a measure of:
Copper level in the serum
Iron loss in faeces
Obesity
Income inequality
2c
single
Corpulence index= actual weight/ desirable weight A value above 1.2 indicates obesity Ref: Park 21st edition, page 178.
Social & Preventive Medicine
null
d32b71db-d463-4c6c-9bc0-4ed5744ee0a5
The type of enzyme inhibition in which succinate dehydrogenase reaction is inhibited by malonate is an example of:
Noncompetitive
Uncompetitive
Competitive
Allosteric
2c
multi
Inhibition of the enzyme succinate dehydrogenase by malonate illustrates competitive inhibition by a substrate analog. Succinate dehydrogenase catalyzes the removal of one hydrogen atom from each of the two-methylene carbons of succinate. Both succinate and its structural analog malonate can bind to the active site of ...
Biochemistry
null
9c66db2c-dde1-405c-8647-23466a0018a6
Which of the following drugs does not cross placenta ?
Heparin
Warfarin
Dicoumarol
Nicoumalone
0a
single
null
Pharmacology
null
a07e013c-6183-4ba5-ab13-a88afb035e73
Which of the following drug will cause hemolysis in G6PD patients:
Cephalosporins
Ampicillin
Chloroquine
Erythromycin
2c
single
Ref: KDT 6th ed. pg. 64 * G6PD is an enzyme present on RBC membrane provides strength to RBC which can counteract free radicals and oxidizing stress of drugs.* In absence of G6PD enzyme, these cells cant bear the stress and results in Hemolysis.* Drugs causing Hemolysis in G6PD deficiency patients are:# Anti malarials ...
Pharmacology
Hematology
19839ee4-e08d-4af4-a067-7f25e22537f6
Target sign on USG is seen in
Congenital hypertrophic pyloric Stenosis
Gastric ulcers
Achalasia
All the above
0a
multi
Target sign - hypoechoic ring and hypertrophied pyloric muscle around echogenic mucosa Centrally on transverse Scan - Seen in CHPS.
Radiology
null
4db5c0a7-5cdf-429c-9683-1afb70f3e99b
Patient is able to recognize voice but not face
Temporal lobe
Occipital
Frontal lobe
Parietal lobe
0a
single
Memory and language problems after temporal lobectomy. Temporary double vision after temporal lobectomy. Increased number of seizures after corpus callosotomy, but the seizures should be less severe. Reduced visual field after a hemispherectomy. Ref: guyton and hall textbook of medical physiology 12 edition page number...
Physiology
Nervous system
c76915a1-c2d6-4f49-ae5f-515095a35329
Tiger eye sign on MRI is seen in -
Halloverden spatz disease
CHPS
Achalasia Cardia
None
0a
multi
Ans. is 'a' i.e., Halloverden spatz diseaseo Tiger eye is an abnormal T2 signal in the globus pallidus seen in Pantothenate kinase-2 (PANK-2) mutation of Holloverden spat disease.
Radiology
Brain Imaging: Inflammatory, Infectious, and Vascular Diseases
173726a0-3629-40e2-8d51-70abfebd4466
Pyogenic infection and brain infarction associated with -
Coagulative necrosis
Liquefaction necrosis
Caseous necrosis
Fat necrosis
1b
single
Ans. is 'b' i.e., Liquefactive necrosis
Pathology
null
35a640bb-f370-47ab-8d41-be236bb9f5a7
In gingival bleeding index given by Ainamo and Bay, positive score is taken at what time after appearance of bleeding on probing?
10 Sec.
20 Sec.
30 Sec.
40 Sec
0a
single
null
Dental
null
a6c73a3e-97d1-4e2d-a7f0-654966afc99d
20 yr old boy is brough to the emergency following an A with respiratory distress and hypotension He has subcutaneous emphysema and no air entry on the right side What is the next best step in the management
sta IV fluids after inseion of wide bore iv line
Needle decompression in the 5th Ics
Shift to Icu and intubate
Positive pressure ventilation
1b
multi
Hlistory of clinical examination is suggestive of tension pneumothorax according to trauma updates needle decompression in adults should be done in 5th Ics at mid axillary line * in children needle in 2nd ICS at MCL ref : baile and love 27th ed
Surgery
All India exam
69495835-836b-4fd7-ad1b-f7ababe71493
A 25-year-old man presents to the outpatient clinic complaining of feeling sleepy all the time, even during the daytime. The symptoms have persisted for years and are now brought to medical attention after falling asleep at work on multiple occasions. He is concerned that he might lose his job. He has no past medical h...
excessive snoring (wife's report)
automatic behavior (wife's report)
restless sleep (wife's report)
paresthesia
1b
multi
The early age of onset and otherwise good health suggest a diagnosis of narcolepsy, which is usually accompanied by other symptomatology. Hypnagogic hallucinations are almost always visual. They occur most frequently at the onset of sleep, either during the day or at night. They are generally very vivid. Cataplexy is a...
Medicine
C.N.S.
6e9212c5-02be-49bc-8ff7-d231c84403ef
Analgesic used for pain associated with STEMI
Morphine
Diclofenac
Paracetamol
Dicyclomine
0a
single
Morphine is a very effective analgesic for the pain associated with STEMI.However, it may reduce sympathetically mediated aeriolar and venous constriction, and the resulting venous pooling may reduce cardiac output and aerial pressure. These hemodynamic disturbances usually respond promptly to elevation of the legs, bu...
Medicine
C.V.S
1e65e0ae-5e93-49fd-9fec-fa9015ba3c60
Otitis and osteomyelitis is seen in?
Hepatitis B vaccine
BCG
Measles vaccine
IPV
1b
single
Ans. (b) BCGRef : OP Ghai 8th ed./191BCG* Although BCG vaccination often causes local reactions, serious or long-term complications are rare. Reactions that can be expected after vaccination include moderate axillary or cervical lymphadenopathy and induration and subsequent pustule formation at the injection site; thes...
Pediatrics
Immunization
362e31d4-f386-4b53-8193-c70246dddd86
Reversible cause of dementia -a) Hypothyroidismb) Alzheimer's diseasec) Vitamin B12 deficiencyd) Vitamin A deficiency
ac
bc
ad
b
0a
single
null
Psychiatry
null
2c547be7-5c76-4a7a-8772-e73cb206fa8c
In Bater's Syndrome, which of the following is not seen-
Metabolic Alkalosis
Hypokalemia
Hypomagnesemia
Decrease in urinary calcium
3d
single
Bater's syndrome - There is loss of transpo function of Thick ascending loop of henle(TALH) Segment of nephron which results in hypokalemic metabolic alkalosis classic BS- typically suffer from polyuria and polydypsia due to reduction in renal concentrating ability . Increase in urinary calcium excretion 20% are hypoma...
Medicine
Kidney
282ae6e6-3a5d-4742-84e3-10f110f0409c
Which of the following steroids is not used topically:
Hydrocoisone
Fluticasone
Triamcinolone
Prednisonlone
3d
multi
Prednisonlone
Pharmacology
null
fdc80bf1-2905-446b-afc2-af0d0f7aaac2
The procedure shown below is
Radical trachelectomy
Partial hysterectomy
Large loop excision of transformation zone
Dilatation and curettage
2c
single
This is LLETZ: Diathermy wire loop is used to remove a portion of Cervix that includes transformation zone with area of CIN.
Gynaecology & Obstetrics
null
810cd91d-0f7f-4f14-99b4-8dc35d7e5f16
Hemorrhagic conjunctivitis occurs with
Herpes zoster
Herpes simplex
Enterovirus
All
2c
multi
C i.e. Enterovirus Acute Haemorrhagic Conjunctivitis or Apollo Conjunctivitis or Jai Bangla Conjunctivitis or Epidemic haemorrhagic conjunctivitis is caused by picorna virus family (usually enterovirus 70)Q. But occasionally Coxsackie virus A-24 or adenovirus //Q also leads to this.
Ophthalmology
null
0966150b-ab42-4089-8aa5-0d8df00c4b36
MDR tuberculosis is defined when M. tuberculosis shows resistance to -
Isoniazid + Rifampicin
Isoniazid + Pyrazinamide
Rifampicin + Pyrazinamide
Rifampicin + Ethambutol
0a
single
Ans. is 'a' i.e., Isoniazid + Rifampicin * Multidrug-resistant TB (MDR-TB) are by definition infected with strains of Mycobacterium tuberculosis resistant to isoniazid and rifampin.* Extremely drug resistant TB (XDR-TB) due to MDR strains that are resistant to all fluoroquinolones and to at least one of three second-li...
Medicine
Infection
4a01fb41-5522-4fee-95a3-a46c18133625
Frost bite is treated by -
Rapid rewarming
Slow rewarming
IV pentoxyphiline
Amputation
1b
single
Ans. is 'b' i.e., Slow rewarming
Surgery
null
96aecd5f-d167-481f-9b42-b884051f969d
Triad of biotin deficiency is
Dermatitis, glossitis, Steatorrhea
Dermatitis, glossitis, Alopecia (314-Basic 8th)
Mental changes, diarrhoea, Alopecia
Dermatitis, dementia, diarrhoea
1b
single
(Dermatitis, glossitis, Alopecia) (407-H) (314-Basic pathology 8th)(Biotin deficiency) - clinical features -Adult = Mental changes (depression, hallucination), paresthesia, anorexia, nausea, A scaling, seborrheic and erythematous rash may occur around the eye, nose, mouth, as well as extremities (407-H)Infant = hypoton...
Pathology
Environment & Nutritional Pathology
9d91a11e-5a94-4e47-9456-2f420212fcfc
True of the following:
Calcium reabsorbed in DCT
90% calcium excreted by glomerulus
Parathormone (PTH) promotes absorption of Ca++ from intestine
PTH promote action of calcitonin
2c
multi
Ans. (c) Parathormone (PTH) promotes absorption of Ca++ from intestine(Ref: Ganong, 25th ed/p.379)Parathormone (PTH) promotes absorption of Ca++ from intestineThis is an indirect action of PTH by increasing vitamin D levels
Physiology
Endocrinology and Reproduction
540abb01-b894-46b6-be4f-e508ae5da26f
Rabies vaccine schedule is:
0,3,7,14,28
8,0,4,0,1,1
8,0,0,4,1,1
8,0,4,0,0,1
1b
single
8, 0, 4, 0, 1, 1
Social & Preventive Medicine
null
65f0ae92-f497-4d74-aa29-7ebba65bf209
Enzymes not used in glycogen metabolism
Glycogen phosphorylase B
Glycogen synthase I
Glycogen synthase C
Glycogen synthase D
2c
single
The liver phosphorylase-b is the inactive form. It becomes active on phosphorylation. The active form is phosphorylase-a.Glycogen synthase exists in two distinct forms that can be interconveed by the action of specific enzymes; active dephosphorylated glycogen synthase(glucose-6-p-independent) and less active, phosphor...
Biochemistry
Metabolism of carbohydrate
ade865ca-91ac-4738-9529-081697898bb6
A community suffering from dry mouth condition is likely to have
Increased incidence of dental caries
Decreased incidence of dental caries
Increased incidence of crack tooth syndrome
Decreased incidence of crack tooth syndrome
0a
single
null
Dental
null
d89a9cfa-d2c5-457d-ad53-e71230dd19c0
Urinary catheterisation indicated in case of acute retention of urine in following conditions
Stricture
Rupture
Postoperative
Carcinoma prostate
2c
single
The most frequent causes of acute retention Male * Bladder outlet obstruction (the most common cause) * Urethral stricture * Acute urethritis or prostatitis * Phimosis Female * Retroveed gravid uterus * Bladder neck obstruction (rare) Both (Male and female) * Blood clot * Urethral calculus * Rupture of the urethra * Ne...
Surgery
Urology
65fa4e00-4b90-4d7c-83d9-43261e62c761
17 years old girl with ovarian tumor, USG showed predominant solid component, CA-125-ve, AFP- ve, ALP raised -
Dysgerminoma
Endodermal sinus tumor
Malignant teratoma
Mucinous cystadenoma
0a
single
Ans. is 'a' i.e., DysgerminomaOvarian mass in 25 year old female suggests the diagnosis.Although dysgerminomas are relatively uncommon among all ovarian neoplasms (only accounting for only about 2%) they account for about 32.8% of malignant ovarian germ cell neoplasms.Majority of cases arise in adolescent and young adu...
Gynaecology & Obstetrics
Ovary
f7c281c5-13ba-4c7a-a2f6-bd0d959f1637
A 23-year-old woman who receives a deep cut to her ring finger by a kitchen knife is unable to move the metacarpophalangeal joint. Which of the following pairs of nerves was damaged?
Median and ulnar
Radial and median
Musculocutaneous and ulnar
Ulnar and radial
3d
single
Metacarpophalangeal joint of the ring finger is flexed by the lumbrical, palmar, and dorsal interosseous muscles, which are innervated by the ulnar nerve. Extensor digitorum, innervated by the radial nerve, extends this joint. Musculocutaneous and axillary nerves do not supply muscles of the hand. Median nerve supplies...
Anatomy
Nerve supply, Nerve Lesions
45d3545d-603a-4883-827c-cde9b36a4615
A child was given Ringer's lactate due to severe blood loss by a road accident. What is the potassium content of Ringers' lactate in mEq/L?
1
2
4
6
2c
single
Composition in 1 Litre of Ringer's lactate: Sodium 130 mEq/L Potassium 4 mEq/L Calcium 3.5 mEq/L Chloride 110 mEq/L Lactate 27 mEq/L Ref: Oski's Pediatrics: Principles And Practice By Julia A. McMillan, Ralph David Feigin, 4th edition, Page 64.
Pediatrics
null
19c4c3a4-027b-412f-acd7-67d21a702b07
The left suprarenal vein drains into:
Inferior vena cava
Lt. renal vein
Rt. renal vein
Portal vein
1b
single
Ans: b (Lt. renal vein)Venous drainage of the suprarenals:Left suprarenal vein drains into the Lt. renal veinRt. suprarenal vein drains into the inferior vena cavaArterial supply.Each gland is supplied by:1) Superior suprarenal artery- Br. of inferior phrenic artery2) Middle suprarenal artery- Br. of abdominal aorta3) ...
Anatomy
Blood Vessels of Abdomen and Pelvis
f7cb9aa2-9199-4a88-bc15-b15f4ff81783
Organophosphate insecticides are all except – a) Dieldrinb) Fenthion c) Diazinond) Propoxure) Lindane
acd
bde
ade
ad
2c
multi
Organo-phosphorus Insecticides: – Malathion – Parathion – Fenthion – Diazinon – Fenitrothion – Chlorpyrifos – Dioxathion – Chlorthion Organo-chlorine Insecticides: – DDT – BHC (HCH) – Lindane – Dieldrin Carbamate Insecticides: – Carbaryl – Propoxur
Social & Preventive Medicine
null
392b8b4f-22b8-4e6c-8817-f4837d044028
Among the drugs given below, which is LEAST likely to be implicated in drug induced hepatitis?
Isoniazid
Streptomycin
Rifampicin
Pyrazinamide
1b
single
null
Pharmacology
null
0cc12a07-286f-495f-8275-76ea2700d318
Ferning ol cervical mucu3 depends on :
Eslrogen
Progesterone
LH
FSH
0a
single
Eslrogen
Gynaecology & Obstetrics
null
6661727e-96ff-4b42-af9f-239946e02966
Which of the following can be given as a single dose antimalarial for P.vivax malaria
Atovaquone + Proguanil
Artemisinin
Quinine + Tetracycline
Pyrimethamine + Sulfadoxime
3d
single
null
Pharmacology
null
78f4c2f3-24bf-44e5-a2bb-fc48579cd092
Hippocampal formation includes all Except
Dentate gyrus
Sibiculum
Amygdaloid
Entorhinal coex
2c
multi
The hippocampal formation in the medial temporal lobe of the brain includes the dentate gyrus, the hippocampus proper and the subiculum
Medicine
C.N.S
086f3a1d-a3bf-4ba1-a7f6-83f335509950
Reactive arthritis is usually caused by -
Shigella flexneri
Shigella boydii
Shigela shiga
Shigela dysentriae
0a
multi
Ans. is 'a' i.e.. Shigella Flexneri o Organisms that have been associated with Reiter Arthritis include the follow ing:C trachomatis (L2b serotype)Ureaplasma urealyticumNeisseria gonorrhoeaeShigella flexneriSalmonella enterica serovars TyphimuriumMycoplasma pneumoniaeMycobacterium tuberculosisYersinia enterocolitica an...
Medicine
Bacteriology
19ffc703-91e8-4d6e-a401-53dd62c1f112
Most common congenital tumour of conjunctiva is
Papilloma
Squamous cell carcinoma
Epibulbar dermoid
Melanoma
2c
single
Commonest congenital tumour of the conjunctiva - Epibulbar dermoid
Ophthalmology
null
b3b67b3b-c146-4a08-a6e5-4e8db5ae05b4
All are true about spinal tuberculosis except ?
Back pain earliest symptom
Dorsolumbar spine commonest site
Exaggerated lumbar lordosis
Secondary to lung infection
2c
multi
Ans. is 'c' i.e., Exaggerated lumbar lordosis Tuberculosis of spine (Pott's spine) The spine is the commonest site of bone and joint tuberculosis. The most common site is Dorsolumbar region. Lower dorsal (thoracic) region is the most common segment involved followed by lumbar segment. The tuberculosis of spine is also ...
Surgery
null
77dd4439-041f-469b-9561-36b182b31a03
Maximum oral bioavailability among statins is of which drug -
Fluvastatin
Atorvastatin
Pravastatin
Simvastatin
0a
single
Ans. is 'a' i.e., Fluvastatino All statins can be absorbed orally (maximum fluvastatin). Food increases absorption of all drugs except pravastatin. Lovastatin and simvastatin undergo extensive first pass metabolism and are administered as prodrugs.Remembero Statins are the most effective and best tolerated hypolipidemi...
Pharmacology
Hypolipidemic
de6e23eb-8209-474b-8159-a56fe9f24069
A 22 year old boy was all alright 2 days back. But since then he claims that people are abusing him and he c/o hearing of voices when no one is around, aggressive behavior since 2 days. He has fever since only 2 days. No past history. Which is the most likely diagnosis?
Dementia
Acute psychosis
Delirium
Delusion
1b
multi
Ans. B. Acute Psychosis* Hearing of voices, Aggressive Behaviors, muttering to self is a sign of psychosis as it less than 1 month it is Acute Psychosis.* It is not fever induced or Delirium because in these conditions the orientation is usually impaired but is not impaired in this question.* In delusional disorder - t...
Psychiatry
Miscellaneous
e5fb985e-d115-4d06-8936-eb8b61599c7d
Breast fed babies as compared to aificially fed babies have all the follwing benefits except -
Lower incidence of diarrhoea episodes
Lower incidence of respiratory infection
Lower incidence of late onset tetany
None
3d
multi
Ans. is None
Pediatrics
null
c7f07a0d-fb59-4cf3-b859-552f020ce5d4
Withdrawal of which of the following causes piloerecton?
Morphine
Cannabis
Smoking
Alcohol
0a
single
Ans. A. MorphineManifestations of morphine withdrawalLacrimationAnxiety & fearSweatingRestlessness rYawningGooseflash (Piloerection).
Psychiatry
null
bf4baa4b-ba58-444a-ba64-dd342aae17d2
Commonest site for fibroid is :
Submucous
Intramural
Subserous
Cervical
1b
single
Intramural
Gynaecology & Obstetrics
null
a2c1e82b-6615-42b5-8c9a-da5c952a5f3e
Semi-circular canals are associated with
Linear acceleration
Angular acceleration
Static equlibirium
Hearing
1b
single
Each semicircular canals has an enlargement at one of its ends called the ampulla, and the ducts and ampulla are filled with a fluid called endolymph. Flow of the fluid through one of the ducts and through its ampulla excites the sensory organs of the ampulla. In each ampulla a small crest called crista ampullaris is p...
Physiology
Nervous system
195d05d4-c95f-42af-952c-8336ec85fc1f
Abnormalities in synthetic function of liver results in: (PGI Dec 2006)
|PT
Hyperbilirubinemia
|Acute phase reactant
Disturbance in Kupffer cells
0a
single
Ans: A (|PT); B {Hyperbilirubinemia} & C (| Acute phase reactants) 411]Liver Function Test - Harrison 17th/ 1918"The most commonly used liver ''function" testsQ are measurements of serum bilirubin, albumin, and prothrombin timeQ. The serum bilirubin level is a measure of hepatic conjugation and excretion, and the serum...
Physiology
Liver and Gall Bladder
93d4dd2f-3598-4c55-9d21-0cd40429e833
Active method of transport is-
Simple diffusion
Facilitated diffusion
Along concentration gradient
Against concentration gradient
3d
single
Ans. is 'd' i.e., Against concentration gradient* Transport across a cell membrane is divided into passive or active, based on whether it is along the concentration gradient or against the concentration gradient.1) Passive transport# It is in the direction of concentration gradient i.e., "Downhill movement"# Does not r...
Physiology
General
87bebfdc-ecba-45e8-a77e-6251ad4c8970
Chaperones are:
Purine metabolism mediators
Antigen presenting cells
Mediators of post-transitional assembly of protein complexes
None of the above
2c
multi
CHAPERONES-FOLDING /SHAPE /ASSEMBLY OF PROTEIN POST-TRANSITIONAL CHANGE They facilitate and our the interactions on the polypeptide surfaces to finally give the specific conformation of a protein. Type 1. Hsp70 system- This mainly consists of Hsp70 (70-kDa heat shock protein) and Hsp40 (40-kDa Hsp). These proteins can ...
Biochemistry
FMGE 2018
845fd308-5ff8-4d4b-a61e-b6b081a9756d
Structures preserved in functional radical dissection of the neck -a) Int. jugular veinb) Sternomastoidc) Lymph nodesd) Accessory nerve
abc
bcd
abd
acd
2c
single
Functional dissection is modified radical neck dissection (MRND Type III ) Modified radical neck dissection is done only selected cases where tumor is very well differentiated and less aggressive like in papillary carcinoma of thyroid with lymph node secondaries . Structures preserved here are sternomastoid muscle , in...
Anatomy
Head and neck
f6a709b0-617b-43a5-a328-323bcd053e32
Humectant in tooth paste serves to
as an abrasive
retains moisture
flavoring agent
foaming agent
1b
single
null
Dental
null
f333a657-b4c7-4fbe-965e-a5863050326d
Route of administration of nitrous oxide is:
Inhalation.
Oral.
Intramuscular.
Intravenous.
0a
single
null
Dental
null
88322e14-17ce-4c36-b51c-e18c3c8703f3
Which of the following has no Tm value ?
Albumin, arginine
Betahydroxybutyrate, glucose
Glucose haemoglobin, phosphate
Urea
3d
single
D i.e. Urea
Physiology
null
4904b604-4789-4b53-b0a9-9f2de9e7f564
All are seen in primary extraglandular Sjogren syndrome except -
Rheumatoid ahritis
Raynaud's phenomena
Lymphoma
Splenomegaly
0a
multi
Ans. is 'a' i.e., Rheumatoid ahritiso Primary Sjogren syndrome is not associated with other autoimmune disorders, e.g. Rheumatoid ahritis. o Sjogren syndrome occurs in elderly (50-60 yrs)female.
Pathology
null
812eb042-8d22-4d73-90cc-3abb12602b99
Adenovirus causes all except -
Hemorrhagic cystitis
Diarrhea
Respiratory tract infection
IMN
3d
multi
Infectious mononucleosis is caused by EBV
Microbiology
null
94c3e97b-c88c-4c4b-8941-e0cf47d25ea2
Traction epiphysis is are
Head of humerus
Lesser tubercle
Deltoid tuberosity
Ciracoid process
1b
single
Traction epiphysis are usually present at the end if bones and develop due to traction by the attached muscle (and are therefore extracapsular), eg Greater (and lesser) tubercle in humerus and greater ( and lesser) trochanter in femur Ref: Gray's39e/p185-210
Anatomy
General anatomy
aa1e5ee8-1bbd-40ba-8f78-d30088285f20
Total body water is
40% of body weight
20% of body weight
10% of body weight
60% of body weight
3d
single
In the average young adult male, 18% of the body weight is protein and related substances, 7% is mineral, and 15% is fat. The remaining 60% is water.(REF: GANONG'S REVIEW OF MEDICAL PHYSIOLOGY 23rd EDITION page no.2)
Physiology
General physiology
28f48704-8184-4283-bcf2-a0f8bc58f411
Best parameter for monitoring HIV disease progression is -
Peripheral blood CD4 + Tcell counts
Plasma levels of HIV RNA
Peripheral blood CD4 + Tcell counts with Plasma levels of HIV RNA
Peripheral blood CD4 + T cell counts or Plasma levels of HIV RNA
2c
single
Ans. is 'c' i.e., Peripheral blood CD4 + Tcell counts with Plasma levels of HIV RNA Laboratory monitoring in HIV infection* The epidemic of HIV infection and AIDS has provided the clinician with new challenges for integrating clinical and laboratory data to effect optimal patient management.* The close relationship bet...
Medicine
Infection
45d22f08-bc46-4f15-b85a-34147cf674bd
Which of the following drugs has maximum chances of absorption from gastric mucosa ?
Morphine sulfate
Diclofenac sodium
Hyoscine hydrobromide
Quinine dihydrochloride
1b
single
- Among the given options, only diclofenac sodium is acidic and remains unionized in the acidic medium of the stomach. Other drugs are basic in nature. So diclofenac has higher chances of getting absorbed from gastric mucosa.
Pharmacology
null
d9137c27-502e-4c77-bbe7-05b59358d32d
A pregnant mother is treated with oral anticoagulant.The likely congenital malformation that may result in the fetus is:
Long bones limb defect
Cranial malformation
Cardiovascular malformation
Chondrodysplasia Punctata
3d
single
Warfarin is an anticoagulant drug. Action : Interferes with the synthesis of the vitamin K dependent factors like II, VII, IX and X. Side effects: Hemorrhage It leads to: – Contradi’s syndrome : skeletal and facial anomalies in the fetus – Chondrodysplasia punctata in the fetus. Miscarriage, IUGR and stillbirths acc...
Gynaecology & Obstetrics
null
c4281d72-8bbd-485d-af93-08602ecfa4f1
The most common side effect of IUCD which requires its removal
Bleeding
Pain
Pelvic infection
Ectopic pregnancy
1b
single
Pain is the second major side effect leading to IUCD removal WHO estimates that 15-40 percent of the IUCD removal appears to be for pain only Pain may be experienced during the inseion and for a few days thereafter and during menstruation Reference: Park&;s textbook of preventive and social medicine, Page no: 498
Social & Preventive Medicine
Demography and family planning
0c144fbe-d5b5-4b10-81a9-881841e4c414
Trombiculid mite can transmit
Indian tick typhus
Q. fever
Relapsing fever
Scrub typhus
3d
single
null
Social & Preventive Medicine
null
3ab7240a-cab6-4113-882f-2c10e1c4d79c
Which of these organelles functions as the digestive system of the cell?
Mitochondria
Rough endoplasmic reticulum
Golgi apparatus
Lysosomes
3d
single
Lysosomes are spherical vesicles enveloped by a single membrane.  Lysosomes are regarded as the digestive tract of the cell, since they are actively involved in digestion of cellular substances-namely proteins, lipids, carbohydrates and nucleic acids.  Lysosomal enzymes are categorized as hydrolases. The lysosomal enzy...
Biochemistry
null
bf51daea-1ea4-4089-8ff3-249806e9a60b
Adenocarcinoma of ethmoid sinus occurs commonly in?
Fire workers
Chimney workers
Watch markers
Wood workers
3d
single
Workers of the furniture industry( woodworkers) develop a demo carcinoma of the ethmoids and the nasal cavity, while those engaged in nickel refining get squamous cell anaplastic carcinoma. (Ref: Textbook of diseases of ENT, PL Dhingra, 7th edition, pg no. 231)
ENT
Nose and paranasal sinuses
3879567e-a763-4224-b454-d6b78c471efc
In nonexposed persons, the level of coproporphyrin in urine is :
Less than 150 microgram/litre
Less than 1000 microgram/litre
More than 500 microgram/litre
None of the above
0a
multi
A i.e. < 150 mg/litres
Forensic Medicine
null
78948081-c616-40a2-82af-d8926aeabdcb
About RCT all are true except
Baseline characteristics are comparable
Dropouts are excluded from the study
Sample size depends on type of study
Bias eliminated by double blinding
1b
multi
null
Social & Preventive Medicine
null
05d432f6-f3a1-4adb-9f96-906d22796c78
Urinary incontinence results from all except:
Neurogenic bladder
Vesico vaginal fistula
Ectopic ureter
Rectovesical fistula
3d
multi
Rectovesical fistula doesn&;t cause urinary incontinence, as the level of fistula is above the sphincter mechanism. Causes of Incontinence: Problems of social control Uninhibited detrusor hyperreflexia and impaired social perception in dementia Storage problems Small bladder capacity owing to fibrosis (tuberculosis, ra...
Surgery
Urology
16558b78-87a6-471c-986b-25d566e018ba
True about PPV is
Increases with prevalence
Decreases with prevalence
No relation with prevalence
Accuracy
0a
multi
The predictive value of a positive test indicates the probability that a patient with a positive test result does indeed have the disease in question. The more prevalent a disease, the more accurate will be the predictive value of a positive screening test. Ref: 25th edition, Park's Textbook of Preventive and Social Me...
Social & Preventive Medicine
Epidemiology
efe8c262-9474-4fd5-bb39-46798829e4ea
Which of the following antiretroviral drugs is a non-nucleoside reverse transcriptase inhibitor -
Zidovudine
Efavirenz
Saquinavir
Stavudine
1b
single
null
Medicine
null
0fbcc627-0d7e-4768-a266-99e0f337062f
Which of the following is most characteristics of granuloma
Epitheliod cell
Giant cells
Fibroblast
Endothelial cells
0a
single
ref Robbins 9/e p97-78 a granuloma is an organized collection of macrophages. In medical practice, doctors occasionally use the term "granuloma" in its more literal meaning: "a small nodule". Since a small nodule can represent anything from a harmless nevus to a malignant tumor, this usage of the term is not very speci...
Anatomy
General anatomy
c4360457-00d9-49ec-8b76-c2e608bf91d4
Milk teeth - Total no. in human being __________
20
28
32
24
0a
single
Deciduous teeth, commonly known as milk teeth, baby teeth, temporary teeth, and primary teeth, are the first set of teeth in the growth development of humans and other diphyodont mammals. They develop during the embryonic stage of development and erupt--that is, they become visible in the mouth--during infancy. they ar...
Pediatrics
Growth and development
99af197f-deae-4caf-8605-a4a74f7fb6ab
Specific type of cells found in infectious mononucleosis:
Downey cells.
Raquet cells.
Arbiskov cells.
None of the above.
0a
multi
null
Pathology
null
7e89bfa3-d2b3-4df6-84fe-0b4c3000a19b
All of the following cause myocardial depression except:
Halothane
Etomidate
Thiopentone
Ketamine
1b
multi
B i.e. Etomidate - Etomidate causes adreno - coical suppressionQ by inhibiting enzymes 11/3 hydroxylase (mainly) & 17 a hydroxylase involved in coisol and aldosterone (mineralocoicoid) productionQ. Vit C supplimentation restores coisol level. - Etomidate and midazolam provide cardiovascular stabilityQ. But etomidate is...
Anaesthesia
null
68400187-3eda-4f3e-8bf1-0ecebfcf57bb
Organism commonly causing diarrhoea in young children is:
Rotavirus
Calci virus
E. coli
Staphylococcus
0a
single
Ans: a (Rota vims) Ref: Nelson, 18th ed, p. 1399; 17th ed, p. 1081; OP Ghai, 6th ed, p. 270In early childhood, the single most important cause of severe dehydrating diarrhoea is rota virus infection.Important pathogens of human viral gastroenteritis* Rota vims\* Adenovirus* Astro vims* Calci vims such as Norwalk agentS...
Pediatrics
Infection
48af5abf-8d22-4bca-bdf9-097d2083489c
All the following are hormonal agents used against breast cancer EXCEPT :
Letrozole
Exemestane
Taxol
Tamoxifen
2c
multi
null
Pharmacology
null
e03519f1-637e-47c7-98d7-eb1eb85677d1
The North Kerelia project evaluate risk factors of
Diabetes
Cancers
Coronary heart disease
Obesity
2c
single
null
Social & Preventive Medicine
null
719daae5-31ca-4dda-8346-966e8f698650
Lateral border of the cubital fossa is -
Brachiradialis
Pronator teres
Flexor Carpi Radialis
Triceps
0a
single
Ans. is 'a' i.e., Brachiradialis Cubital fossaLateral boundryBrachioradialisMedial boundryPronater teresBaseLine joining the two epicondyles of humerusApexPoint joining lateral and medial boundriesFloorBrachialis, supinatorRoofSkin, superficial fascia (containing medial cubital vein, lateral and medial cutaneous nerve ...
Anatomy
Upper Extremity
8ee4f02b-6692-40dc-8e30-f789d351771c
A 50-year-old man with muscle pain and fever for a month now notes darker colored urine for the past 2 weeks. On physical examination, he has palpable purpuric lesions of his skin. Urinalysis shows hematuria and proteinuria. Serum laboratory findings include mixed cryoglobulinemia with a polyclonal increase in IgG, as ...
Giant cells and macrophages
Medial fibrinoid necrosis
Micro abscesses
Mycotic aneurysms
1b
single
Microscopic polyangiitis involves small vessels, typically capillaries. Kidneys and lungs are commonly involved, but many organs can be affected. There may be an underlying immune disease, chronic infection, or drug reaction. Giant cell arteritis typically involves arterial branches of the external carotid, most often ...
Pathology
Blood Vessels
2723d0b3-4e0f-4c09-88dc-aa21ddbf9d99
MHC class I represented on -
All cells
All nucleated cells
RBCs
None
1b
multi
Ans. is 'b' i.e., All nucleated cells o MHC class I is found on the surface of all nucleated cells and platelets.
Pathology
null
36531a23-c4c7-4451-a594-eb2658196f9d
Iodine uptake is seen in the following organs
Ovary
Thyroid
Parathyroid
Adrenal gland
1b
single
Ans. B Thyroida. Iodine Trapping (Iodine pump)b. Iodide uptake is a critical first step in the thyroid hormone synthesis by the thyroid.c. Iodide uptake from circulation, is mediated by Na+/I- symporter (NIS), which is expressed at the basolateral membrane of the thyroid follicular cells. It is an example of secondary ...
Physiology
Thyroid
a2fffbd4-2551-44de-94e9-018362d1b6bb
An acute apical abscess is usually a result of:
Periodontal pocket
Occlusal interference
Necrotic pulp
Chronic gingivitis
2c
multi
null
Pathology
null
4ceab553-5d8d-4938-9c22-b2cd639b973a
Anti leprosy drug causing ichthyoses is -
Dapsone
Clofazimine
Rifampicin
Clarithromycin
1b
single
Ans. is 'b' i.e., Clofazimine Acquired ichthyosis (Ichthyosis acouista)o Acquired ichthyosis is seen in : -Deficiency:- Protein, Vitamin A, Kwashiorkor, Marasmus.Infection:- Leprosy, AIDSSenile ichthyosis: -ElderlySystemic diseases: -SLE, DM, hypothyroidism, Sarcoidosis, liver & kidney diseases.Malignancy, especially: ...
Unknown
null
2440770d-68ff-4446-97d9-0b19f1beadea
False about Wolman disease is -
It is a lysosomal storage disorder
It is characterized by deficient acid lysosomal lipase
It shows autosomal AR inheritance pattern
It is characterized by adrenal calcification and corneal clouding
3d
multi
Wolmans disease is due to deficiency of the enzyme lysozomal acid lipase . Major accumulating metabolites being cholestrol esters and triglycerides. It is a lysosomal storage disease, also shows autosomal ressesive inheritance. so answer is option 4. Robbins basic pathology. 7th edition . Chapter Genetic disorders. Pge...
Pathology
Endocrinology
e36c2f5c-d8ce-4d31-b396-0e1dc6cceae1
Sign of pubey in boys ?
Enlargement of penis
Enlargement of testes
Appearance of pubic hair
Appearance of axillary hair
1b
single
Ans. is 'b' i.e., Enlargement of testes In girls, the first visible sign of pubey is the appearance of breast buds (Thelarche), between 8-12 years of age. In boys the first visible sign of pubey is testicular enlargement, beginning as early as 91/2 yr.
Pediatrics
null
dc9931bb-f7a2-4bef-b71c-a496f044126a
In rickets all are seen EXCEPT:
Craniotabes
Increased acid phosphatase
Bow legs
Increase alkaline phosphatase
1b
multi
ANSWER: (B) Increased acid phosphataseREF: Nelson Textbook of Paediatrics 17th edition page 186-187"Alkaline phosphatase not acid phosphatase is increased in rickets"RICKETS is a softening of bones in children due to deficiency or impaired metabolism of vitamin D, magnesium, phosphorus or calcium, potentially leading t...
Pediatrics
Vitamin D
5c22140f-96d7-419b-8ed9-e9ded5545dc0
All of the following decrease bone resorption in osteoporosis except:
Alendronate
Etidronate
Strontium
Teriparatide
3d
multi
Ans. (D) Teriparatide(Ref: CMDT 2010/1041; KDT 8/e p365)Teriparatide acts by stimulating the formation of bone whereas bisphosphonates act by inhibiting the resorption of bone. Strontium ranelate has both of these properties.
Pharmacology
Endocrinology