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135
20a6b6da-7205-42db-85c8-f95e09798423
Most frequent cause of neonatal thrombocytopenic purura is -
Infection
Drug idiosyncrasy
Large haemangiomas
Erythroblastosis
0a
single
Ans. is 'a' i.e., Infection o Amongst the given options, only infection causes neonatal thrombocytopenia.
Pediatrics
null
7bb78cdf-b65a-4e4b-b12f-0eb233c29c8b
Which of the following disease is caused by inflammatory reaction involved by neutrophils?
Acute respiratory distress syndrome
Septic shock
Asthma
Ahritis
0a
single
Diseases Caused by Inflammatory ReactionsDisordersCells and Molecules involved in injuryAcute Acute respiratorydistress syndromeNeutrophilsAsthmaEosinophils; IgE antibodiesGlomerulonephritisAntibodies and complement; neutrophils, monocytesSeptic shockCytokinesChronicAhritisLymphocytes, macrophages; antibodies?AsthmaEos...
Pathology
General pathology
89f8a4d6-b6a3-4159-bfb8-4f8e710aa5cb
Best way to dispose e-waste is?
Burning
Incineration
In a landfill
Recycling
3d
single
ANSWER: (D) RecyclingREF: With textElectronic waste, popularly known as 'e-waste* can be defined as electronic equipments/ products connects with power plug, batteries which have become obsolete due to: advancement in technology, changes in fashion, style and status, nearing the end of their useful life. (REF: Indian I...
Social & Preventive Medicine
Hospital Waste
7b274121-4971-47ab-8d24-2bfa58eebd1c
Which of the following structure develop in ventral pa of ventral mesentery of stomach?
Falciform ligament
Hepatogastric ligament
Lesser omentum
Splenogastric ligament
0a
single
- Falciform ligament develops in the ventral pa of the ventral mesentery - Lesser omentum (hepatogastric ligament) in the dorsal pa of ventral mesentery.
Anatomy
Mesentry, neurovascular bundle
8963e63d-f43e-4f28-aa48-1060390490ee
ATP yield in Beta oxidation of palmitic acid ?
106 ATP
102 ATP
120 ATP
110 ATP
0a
single
Energetics of Beta Oxidation (ATP Yield) - Palmitic acid (16 C) needs 7 cycles of beta oxidation. So, it gives rise to 8 molecules of acetyl CoA. Every molecule of acetyl CoA when oxidised in the TCA cycle gives 10 molecules of ATP. Each molecule of FADH2 produces 1.5 molecules of ATP and each NADH generates 2.5 molecu...
Biochemistry
Metabolism of carbohydrate
49453b8e-5511-47da-bab8-98cf7f95f97e
Immunoprophylaxis of leprosy includes -
BCG
MMR
ICRC bacillus
Anthrax vaccine
0a
single
For immunoprophylaxis , trials in different population groups with BCG vaccine either alone or in combination with other vaccine have shown protective efficacy ranging between 28% and 60%. Reference; Park&;s Textbook of preventive and social medicine, 24th edition.Pg no. 344
Social & Preventive Medicine
Communicable diseases
71a63683-ada1-4288-ab94-31bb1a060ecc
A baby can follow an object till 180o, can hold neck, can sit with suppo but cannot sit without suppo. The age of the baby is:
1 month
2 months
4 months
6 months
3d
single
Following an object up to 180deg comes at 2 months, Neck holding comes at 3 months, Sitting with suppo is attained at 6 months; So, the age of this baby is 6 months
Pediatrics
Impoant Motor Milestones
1978f2a8-8baa-425e-96fa-cd8b2f2a5635
Misoprostol has been found to be effective in all of the following except
Missed aboion
Induction of labour
Menorrhagia
Prevention of postpaum hemorrhage (PPH)
2c
multi
Misoprostol is not used. Treatment modalities include eostrogrn therapy ,progesterone initial dose of 10-30 mg a day,should arrest bleeding in 24-48 hrs,after which 5 mg given daily for 20 days,ethamsylate,NSAID,antifibrinolytic agents like tranexamic acid,Gnrh is employed if the above fail,SERM like ormeloxifene etc.....
Gynaecology & Obstetrics
Abnormal labor
7c414ff4-1c98-4468-975d-76a984e8f45b
All of the following are usual features of left atrial Myxoma, except -
Raised ESR
Pyrexia
Markedly enlarged left atrium
Systemic Embolism
2c
multi
null
Medicine
null
f54414ac-ee26-429e-aa67-50d4f3a2112f
True about choledochal cyst is -
Always extrahepatic T/t
T/t is cystojejunostomy
Excision is ideal t/t
Drainage is t/t of choice
2c
multi
null
Surgery
null
7fce1e4c-cf9c-416b-8f8d-366aa549c933
Bland cholestasis is caused by all of the following drugs, except
Androgen
OCP
Cyclosporine
Chlorpromazine
3d
multi
Answer is D (Chlorpromazine) Chlorpromazine is associated with inflammatory cholestasis and not with Bland (non inflammatory) cholestasis.
Pharmacology
null
9f6cb4ba-4eb8-4f19-8aa6-bcf66a710131
Cerebral Cysticercosis
Commonly manifests with localizing signs
May present with dementia
Rarely occurs in children
Usually presents with generalized seizures
0a
multi
(A) Commonly manifests with localizing signs # "These is wide variety of presentation of Neurocysticercosis depending on the intensity of the infestation, the localization of cystecerci and the degree of inflammatory reaction.> Epilepsy (seizure activity) is the most common manifestation occuring in upto 50% cases.> Cy...
Medicine
Miscellaneous
fe43aecd-b8ef-4660-bded-b6d31321c192
In a patient if administration of exogeneus vasopressin does not increase the osmolality of urine the likely cause is
SIADH
Psychogenic polydipsia
Renal Hyposensitivity to ADH
ADH Deficiency
2c
single
Answer is C (Renal Hyposensitivity to ADH): Failure of urine osmolality to rise even after administration of exogenous ADH/vasopressin suggests a diagnosis of Nephrogenic Diabetes Insipidus due resistance to action of vasopressin on the Renal tubule (Renal Hyposensitivity to ADH).
Medicine
null
424aa347-6be2-4ee5-a079-be9ae7c04dae
A child presents with recurrent bouts of severe cough followed by an audible whoop. Which of the following is considered the best type of specimen to isolate the organism and confirm the diagnosis.
Nasopharyngeal swab
Cough plate
Throat Swabs
Anterior Nasal Swab
0a
single
Presence of recurrent bouts of severe cough followed by an audible whoop suggests a diagnosis of pertusis (Whooping cough). Nasopharyngeal Swab is the single best specimen to isolate the organism from the options provided.
Pediatrics
null
6c65711e-aaf6-42b4-a1d8-a95d65d50cf4
The vitamin deficiency implicated in metaplasia of respiratory epithelium is:
Vitamin-A
Vitamin-C
Vitamin-B
Vitamin-E
0a
single
Factors that incriminated in the pathogenesis of lung cancer: Chromosome deletions (paicularly 11p, 13q, 17p, and 3p) Tumor suppressor gene mutations (p53, Hap-1, ErbAb, etc) High-level expression of both growth factor genes (insulinlike and transferrinlike growth factors) Epidermal growth factor receptors (HER2/neu,EG...
Physiology
null
0210e35e-002b-4be0-8dbd-391973903c38
A 40 year old female patient complains of excessive bleeding. Patient gives a history of road traffic accident 5 hours ago and had a lacerated wound on lower back region. Blood grouping test reveals presence of antigen A and antigen H. Anti Rh D antibody and anti B antibody are also present. This patient can receive tr...
A positive
O positive
B negative
Bombay blood group
3d
single
→ Apart from A< B and O, RBC of type O contains large amount of another antigen called H substance. → H substance is genetically different from ABO, but is a precursor of A and B antigens. → An O group individual who inherits A or B genes, but fails to inherit H gene from either parent is called Oh phenotype or Bombay ...
Pathology
null
f64ec9e0-6077-4547-9173-da0b7da7bf8b
HTLV-1 is also known as:
HIV
ATLV
RSV
ALV
1b
single
Ans. b. ATLV
Microbiology
null
c89f1a97-f76f-4320-afa8-09db86a3f26b
Following are gastrointestinal hormones except :
CCK- PZ
GIP
Chymotrypsin
Motilin
2c
multi
C i.e. ChymotrypsinActivatorProenzyme/ EnzymeTrypsin (activates- Cliymotrypsinogens /chyinotrypsinQonly pancreatic- Pro carboxypeptidase A/enzymes)carboxypeptidase A - Procarboxypeptidase B/ carboxypeptidase B - Pro-colipase/colipase - Pro-elastase/elastase - Pro-phospholipase A2/phospholipase A2Enteroeptidase- Trypsin...
Physiology
null
45f7484d-4099-4c2f-ade9-c65c5294415f
\r\nAll of the following are true about Aedes mosquito, except:
It transmits dengue fever
It breed in stagnant water
They are recurrent day time biters
Its eggs cannot survive more than one week without water
3d
multi
Aedes Aegypti are recurrent day time biters and breed in stagnant water. It transmits dengue fever. Aedes Aegypti eggs can remain ble for long periods under without water. Hence it is carried to many pas of the world as dry eggs in suitable containers. Ref: Physician's Guide to Ahropods of Medical Impoance, 4th Edition...
Social & Preventive Medicine
null
dba529ac-bc38-4ae0-b16e-e196ef384813
Percentage of renal stones which are radio opaque ?
10%
25%
37%
90%
3d
single
Ans. is `d' i.e. 90%
Surgery
null
04fe126c-8138-494f-89fa-c09beb8530c2
During pregnancy, fibroid may have all of the following complications except: March 2009
Metastasis
Pain
Post paum hemorrhage
Preterm labour
0a
multi
Ans. A: Metastasis Pregnant women with fibroids are at increased risk for: Pain Breech presentation Malposition Higher incidence of cesarean delivery Preterm bih Premature rupture of the membranes Postpaum hemorrhage Placental abruption Submucosal, fibroids located beneath the placenta, and fibroids 7 to 8 cm in diamet...
Gynaecology & Obstetrics
null
62d0a735-88aa-491d-8388-57e657ccbc2d
Which one of the following muscle protein plays an important role in contraction of both smooth and striated muscle?
Calmodulin
Troponin
Tropomyosin
Actin
3d
multi
Ans. D. Actina. In both smooth and striated muscle, contraction is produced by the cross- bridge cycle in which the cross-bridge on the thick filament binds to the actin molecule on the thin filament.b. In excitation-contraction coupling in striated muscle, calcium initiates contraction by binding to troponin.c. The ca...
Physiology
General
ae835e6f-2272-4558-bc39-ca6b214ae6de
After birth, care of eye of newborn is by
AgNO3 eye drop
Antibiotics
Normal saline
Crede’s method
0a
single
null
Social & Preventive Medicine
null
da1cf954-bff7-4e65-8e6d-68ce70c6988d
Which of the following is not a feature of rheumatoid ahritis?
Heberden nodes
Swan neck deformity
Ulnar detion of fingers at metacarpopalyngeal joint
Symmetric reduction of joint space
0a
single
Heberden does is a feature of osteoahritis and not rheumatoid ahritisImpoant hand deformities of hand in RABoutonniere deformity: flexion contracture of PIP joint and extension DIP jointSwan neck deformity: hyperextension of PIP joint and flexion at DIP joint(Refer: Mohindra's Fundamentals of Ohopedics, 2nd edition, pg...
Orthopaedics
All India exam
692b91a0-e29d-438c-b0a5-408f65adcfd1
True regarding excitation contraction coupling in smooth muscles is :
Presence of troponin is essential
Sustained contraction occurs with high calcium concentration
Phosphorylation of actin is required for contraction
Presence of cellular calcium is essential to cause muscle
3d
multi
D i.e. Presence of cellular calcium essential to cause muscle contraction
Physiology
null
4e4b1088-b359-440b-851c-1bcd4608e45a
Most common symptom of symptom of alcohol withdrawal is
Bodyache
Tremor
Diarrhoea
Rhinorrhea
1b
single
The most common withdrawal syndrome is a hangover on the next morning. Mild tremors, nausea, vomiting, weakness, irritability, insomnia and anxiety are the other common withdrawal symptoms. Sometimes the withdrawal syndrome may be more severe, characterised by one of the following three disturbances: delirium tremens, ...
Psychiatry
Substance abuse
aa9ca47c-703d-470d-b30a-2e04bc4a4365
Study of multiplication of proteins in disease process is called
Proteomics
Genomics
Glycomics
Nucleomics
0a
multi
Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes.Glycomics is the comprehensive study of glycomes (the entire complement of sugars, whether free or present in more complex molecules of an organism), including genetic, physiologic, pathologic, and othe...
Biochemistry
Metabolism of nucleic acids
f54992e3-6b45-4aa3-87b2-40658633ec6c
Skin grafting is absolutely C/I in which skin infection?
Staphylococus
Pseudomonas
Streptococus
Proteus
2c
single
Ans is 'c' i.e. Streptococcus "The skin graft generally survives when placed over the wounds containing less than 105 organisms per gram of tissue unless the organisms are streptococci, which can rapidly dissolve transplanted skin." - S. Das 3/e, p 142
Surgery
null
03009447-dc4f-4ee3-9c35-1c9928a917c8
Most sensitive investigation for cystic fibrosis is?
CT scan
Ultrasound
Sweat electrolytes
Tomogram
2c
single
Ans. (c) Sweat electrolytesRef: Harrison's Medicine 18th ed p 2149-50
Medicine
Genetics
05211e03-6a60-475c-978a-9c721c2c352a
An Infant brought to the clinic with non-biliousf projectile vomiting. The investigation of choice includes\
Barium meal
Abdominal ultrasonograpy
Flexible Endoscopy
Sigmoidoscopy
0a
single
(A) Barium meal # Clinical features of Hypertrophic pyloric stenosis:> Characteristically it is a first-born male child that is most commonly affected. The condition is most commonly seen at 4 weeks after birth ranging from the third week to, on rare occasions, the seventh.> Inexplicably, it is the time following birth...
Psychiatry
Miscellaneous
6e9f9bd2-20a7-4e1e-b573-e0ef3794a864
Extended spectrum beta lactamases (ESBLs) are characterized by activity against all except:
Penicillinases
Cephalosporinases
Oxyimino-cephalosporinases
Carbapenems
3d
multi
CARBAPENEMS: lmipenem :It is an extremely potent and broad-spectrum Beta-lactam antibiotic whose range of activity includes grampositive cocci, Enterobacteriaceae, Ps. aeruginosa, Listeri.
Pharmacology
Chemotherapy
cd04b14f-6f4c-4a3d-9bec-6f6477ddee5e
Increased LH:FSH ratio is found in :
Premature menopause
Sheehan syndrome
Polycystic ovary syndrome
Turner's syndrome
2c
single
Polycystic ovary syndrome
Gynaecology & Obstetrics
null
56d9a1f7-b5c4-4604-a0ac-9dd5cf436cc5
Type of graft, best suited for renal transplantation ?
Allograft
Autograft
Xenograft
Isograft
3d
multi
Ans is 'd' i.e., Isograft Although the best graft is autograft, a renal graft can obviously not be an autograft. So the best renal graft is an isograft.
Microbiology
null
39b81ed9-324d-458d-a067-07e0a8d4a241
The ability of a test to detect true negatives is:
Sensitivity
Specificity
PPV
NPV
1b
multi
Ref: 21st edition Park. Pg 128Explanation:SensitivityAbility of the test to identify true positivesSpecificityAbility of the test to identify true negativesPositive predictive valueProbability that a patient with positive test result truly has the diseaseNegative predictive valueProbability that a patient with negative...
Social & Preventive Medicine
Screening for Disease
43c1e6b0-0735-4c08-8d36-cac4733a2066
Which laser is used in the management of after cataracts -
Argon
Krypton
YAG
Excimer
2c
single
After cataract, if thin, can be cleared centrally by a YAG laser capsulotomy.
Ophthalmology
Lens
7a1a7792-bef9-4f5c-bd39-28846fefe15d
Superficial second degree burns heal by
1 week
2 weeks
3 weeks
4 weeks
1b
single
Superficial second degree burns usually heal with minimum scarring in 10-14 days unless they become infected. Second degree burns are divided into superficial and deep burns. Superficial dermal burns: Erythematous and painful, blanch to touch and often blister. They heal in 10-14 days. Deep dermal burns : Involve the r...
Anatomy
General anatomy
7fbb5f1b-35ce-4cde-aeab-cb5a8d0622e8
Syndrome characterized by an elaborate delusion that the patient is passionately loved by another person is also known as:
Ekbom's syndrome
De Clerambault's syndrome
Querulous paranoia
Othello syndrome
1b
single
Erotomania (de Clerambault's syndrome): Condition in which a person holds a delusional belief that another person, usually of a higher social status, is in love with him/her. Erotomanic tries to get close to the person through telephone calls, e-mails, letters, gifts and visits. MC in women than in men. Ekbom syndrome ...
Forensic Medicine
Forensic Psychiatry
deb31985-fe35-436d-b463-1a9d1ef9b2de
Adrenaline in LA causes:
Increase the dose of LA
Less systemic absorption
More time of action
All of the above
3d
multi
Ans: d (All of the above) Ref: KDT, 6th ed, p. 356; Bailey and Love, 24thed, p. 49* Addition of adrenaline (commonly 1:200000 to 1: 125000 concentration) to the local anaesthetic solution hastens the onset and prolongs the duration of action and permits a higher dose of drug to be used as it is more slowly absorbed int...
Anaesthesia
Local and Regional Anesthesia
f1644897-584b-4782-a359-90d6b28395ce
A drug used for Buerger's disease?
Propranolol
Xanthinol nicotinate
GTN
All the above
1b
multi
A drug used in Buerger's disease is Xanthinol nicotinate. Complamina retard (xanthine nicotinate) tablet was used daily once earlier. Now, graded injection of xanthine nicotinate 3000 mg from day 1 to 9000 mg on day 5 is used to promote ulcer healing. It also helps to increase claudication distance as a temporary basis...
Surgery
null
e0f37d7e-02dc-4cf7-86d3-f5c07899fb61
Methotrexate is an example for which of the following class of drugs?
Antibiotic
Alkylating agent
Biologic response modifier
Folic acid analogue
3d
single
Ans: D (Folic acid analogue) Ref: The Pharmacological basis of therapeutics bv Goodman & Gilman - 12th edition, page no. 1669 -767/Explanation:"Methotrexate is an anti-metabolite which is a folic acid analogue." Ref: G&GClassification of Anti-Cancer DrugsAnti-metabolitesPemetrexed5 FUCapecitabineCytarabineGemcitabine5-...
Pharmacology
Anti-Neoplastic Agents
3103abb3-c4af-44b5-b618-40a0a935fa52
A 45-years-old man who works in textile company visited hospital for routine health check-up. He prepares dyes in company from last 18 years. Which of the following investigation would you recommend for this patient?
Pulmonary function tests
Liver function tests
Urine examination
Complete blood count.
2c
single
Dye stuffs & dyeing industries, rubber, gas & electric cable industries are associated with carcinoma of bladder (transitional cell carcinoma). Bladder cancer is caused by aromatic amines, which are metabolized in the body & excreted in the urine. Possible bladder carcinogens are: Beta-naphthylamines, benzidine, para-a...
Social & Preventive Medicine
Environment
53c4883e-86a2-44de-bb03-38aa0971cc1f
Which of the following joints findings Is most suggestive of an inflammatory, rather than an osteroahritis cause of joints pain?
Painful range of motion
Crepitus
Bony aicular enlargement
Swelling and warmth
3d
single
The five classical signs of inflammation are heat, pain, redness, swelling, and loss of function (Latin calor, dolor, rubor, tumor, and functio laesa). Ref - Internet
Medicine
Immune system
326fefe4-25f7-401c-9112-38c211a822b1
Nerves are not involved in ?
Tuberculoid leprosy
Lepromatous leprosy
Indeterminate leprosy
Borderline tuberculoid leprosy
2c
single
Ans. is 'c' i.e., Indeterminate leprosy
Skin
null
d536075a-2268-4e1a-817e-525f454cf251
Secretin is produced by which of the following duodenal cells?
I cells
T cells
M cells
S cells
3d
single
Ans. D. S cells. (Ref. Guyton's Medical Physiology 11th/pg. 801; Ganong 23rd/ Chapter 36).GI secretory products1. Nitrous oxide: Causes smooth muscle relaxation (e.g., elower oesophageal sphincter (LES) relaxtion).2. Gastrin: Secreted in response to gastric distention, vagal stimulation, and amino acid entering the sto...
Physiology
G.I.T.
1fb43edd-2cb2-44cb-84f3-313ac468e69e
First symptom in vulval cancer is-
Pain
Pruritus
Ulceration
Bloody discharge
1b
single
Ans. is 'b' i.e., Pruritus o Women with VIN and vulvar cancer commonly present with pruritus and a visible lesion.# However, pain, bleeding, and ulceration may also be initial complaints.
Gynaecology & Obstetrics
Valva
0b85c902-0dc8-4c70-8799-e28b6dceb1e6
Incised looking lacerated wound site is?
Forehead
Hand
Thorax
Abdomen
0a
single
Ans. is 'a' i.e., forehead LACERATIONS (Tear or Rupture)o Lacerations are tears or splits of skin, mucous membrane and underlying tissue (e.g., muscle or internal organs). Lacerations are produced by application of blunt force to broad area of the body, which crush or stretch tissues beyond the limits of their elastici...
Forensic Medicine
Injuries by Sharp Force
210e857c-b23b-4f78-96fe-d226f3b11dc8
False about nerve entrapment syndromes
Guyon's canal syndrome - ulnar nerve
Cubital tunnel syndrome - ulnar nerve
Cheiralgia paresthetica - femoral nerve
Tarsal tunnel syndrome - posterior tibial nerve
2c
multi
Nerve entrapment syndromes  Carpal tunnel syndrome - Median nerve  Cubital tunnel syndrome - Ulnar nerve Guyon's canal syndrome - Ulnar nerve  Pyriformis syndrome - Sciatic nerve  Meralgia Paresthetica - Lateral cutaneous nerve of thigh  Cheiralgia Paresthetic - Superficial Radial nerve Tarsal tunnel syndrome - Poster...
Orthopaedics
null
a2f01d80-2049-4155-8ba7-68aa1a47ef94
Keshan's disease is due to deficiency of:
Selenium
Zinc
Copper
Iron
0a
single
Keshan's Disease Deficiency of Selenium (Se) Affects: Children Women of child bearing age CLINICAL FEATURES: Cardiomyopathy Muscle weakness Hypothyroidism Eczema Increased risk of stroke Hypeension Cancer Selenium Sources- seafood and meat, nuts Deficiency - Keshan's disease Toxicity - Selenium toxicity lead to Selenos...
Biochemistry
FMGE 2019
8b4a033b-5e7d-4e2e-86df-8e527eda696b
Bones ossified at bih:
Lower end of femur
Calcaneum
Upper end tibia
All
3d
multi
A i.e., Lower end femur B i.e., Calcaneum C i.e., Upper end tibia
Anatomy
null
837bc195-b0a2-4739-af7a-a58e6b50d665
The largest component of amalgam alloy is:
Silver
Tin
Zinc
Copper
0a
multi
null
Dental
null
f79d62c5-a436-4a26-8643-7ba3d8ae75ee
Localized myogenic infection is caused by which bacteria?
Staphylococcus
Clostridium
Cornybacterium
Streptococcal
0a
single
ANSWER: (A) StaphylococcusREF: Harrisons 18th ed chapter 125Important causes of muscle infections:Most common cause of pyomyositis : staphylococcus aureusGas gangrene : CL PerferingensSevere muscle pain : pleurodynia due to coxsackie B, trichinosisRhabdomyolysis : clostridium , streptococcal
Microbiology
Staphylococci
97bc6a1d-d772-43aa-bdbc-8528bcd42f51
A56 years old patient presents after three days of cataract surgery with a history of increasing pain and decrease of vision after an initial improvement the most likely cause would be
Endophthalmitis
After cataract
Central retinal vein occlusion
Retinal detachment
0a
single
Pain which is increasing along with decrease in vision paicularly after only three days of cataract surgery strongly suggest endophthalmitis
Ophthalmology
Lens
d6bb20bf-62cd-4156-bf97-0377b9a7c824
Oedipus complex has been described by -
Plato
Socartes
Freud
Huxley
2c
single
Oedipus complex is described by Freud in psychosexual stages of development.
Psychiatry
null
07cf326a-bb3e-43b9-9474-6b3f307f2313
On microscopic examination, eggs are seen, but on saturation with a salt solution, no eggs are seen. The eggs are likely to be of -
Trichuris trichiura
Taenia solium
Ascaris lumbricoides
Ancylostoma duodenale
1b
single
null
Microbiology
null
f85038e4-e70b-4a63-b316-5642f0b3f4fc
Most frequent site of tubal ectopic pregnancy is
Interstitial
Isthmic
Ampulla
Infundibulum
2c
single
Nearly 95 percent of ectopic pregnancies are implanted in the various segments of the fallopian tube. The ampulla (70 percent) is the most frequent site, followed by isthmic (12 percent), fimbrial (11 percent), and interstitial tubal pregnancies (2 percent).The remaining 5 percent of non-tubal ectopic pregnancies impla...
Gynaecology & Obstetrics
General obstetrics
11ed1ae2-47ca-42ff-aac5-865f62508c55
A one year old child having leucocoria was detected to be having a unilateral, large retinoblastoma filling half the globe. Current therapy would involve:
Enucleation
Chemotherapy followed by local dyes
Direct Laser ablation using photo dynamic cryotherapy
Scleral radiotherapy followed by chemotherapy
0a
single
A i.e. Enucleation
Ophthalmology
null
51233c9d-5d8b-488d-81b9-c3677501fa3d
After removal of granulation tissue from periodontal pocket the hard structure seen is
Periosteum
Transseptal fibres
Sharpey's fibres
Organized granulation tissue
1b
single
null
Dental
null
c8bc7f56-e74e-4c48-855d-a62d58da30ba
All are true regarding folliculogensis and ovulation except
Follicular development and differentiation takes about 85 days
AMH suppos follicular development and oocyte maturation
First phase of follicular growth is gonadotrophin insensitive
Elevated and static levels of estradiol is essential for ovulation
3d
multi
Peak level of LH is required for ovulation Peak level is 75ng/ml It lasts for 24 hours Ref: Shaw Gynecology 17 e pg 40.
Gynaecology & Obstetrics
Reproductive physiology and hormones in females
06a059e8-ce09-46d0-81ba-2bf989c7f059
A 16-year-old boy arrives to your office soon after beginning basketball season. He states that he has had progressive pain in his knees. A physical examination reveals, in addition to tenderness, a swollen and prominent tibial tubercle. Radiographs of the area are unremarkable. Which of the following is the most likel...
Osgood-Schlatter disease
Popliteal cyst
Slipped capital femoral epiphysis
Legg-Calve-Perthes disease
0a
multi
This history is typical of Osgood-Schlatter disease. Microfractures in the area of the insertion of the patellar tendon into the tibial tubercle are common in athletic adolescents. Swelling, tenderness, and an increase in size of the tibial tuberosity are found. Radiographs can be used to rule out other conditions. Tre...
Pediatrics
Growth, Development, and Behavior
fb00f2c4-c96c-4db3-97f4-01484ecef1b6
All of the following statements about Thrombotic thrombocytopenic purpura (TTP) are true, Except :
Microangiopathic Hemolytic Anemia
Thrombocytopenia
Normal complement levels
Grossly abnormal coagulation tests
3d
multi
Answer is D i.e. (Grossly abnormal coagulation tests) Tests of coagulation are essentially normal in Thrombotic Thrombocytopenic Purpura (TTP). Clinical Pentad + Normal Tests for coagulation : TTP Clinical Pentad of TTP
Medicine
null
3e58499f-3a81-4dcd-bc9f-6ca644779dd4
Simple anchorage refers to
Closure by tipping
Closure by bodily movement
Closure by rotation
Closure by intrusion
0a
single
null
Dental
null
50ae24ac-c799-49e2-a820-8f39f295d517
Prothombin Time (PT) of a patient is 26, Control PT is 13 seconds and Sensitivity index is 1.41. What will be the INR of this patient?
26/13
(26/13) x 1.41
(26/13)+1.41
(26/13)1.41
3d
single
The INR calculation has become a standard method for monitoring the PT values. It is calculated as = (patient prothrombin time/mean prothrombin time)ISI. Patient prothrombin time = 26 Mean prothrombin time = 13 ISI (International Sensitivity Index) = 1.41 INR = (26/13)1.41 Ref: Laboratory Hematology Practice By Kandice...
Pharmacology
null
c19a6f2a-938f-43f1-a6df-b89d72d4f418
Which event will NOT occur during depolarization phase?
Na+ channels open
Ca+ channels open
K+ channels open
None of the above
2c
multi
Na+ channels open, increasing the permeability of the cell membrane to Na+. Sodiumions then diffuse into the cell, causing depolarization. This causes K+ channels to close quickly, decreasing the permeability of the cell membrane to K+. The decreased diffusion of K+out of the cell also causes depolarization. Ca2+ chann...
Medicine
null
bcd6d29e-f27a-4d3d-87c5-9ab466aa3092
All the following are features of Endotoxins Except
Lipopolysaccharides
Proteins
Heat stable
No enzymic action
1b
multi
Distinguishing features of exotoxins and endotoxinsExotoxinsEndotoxinsProteinsLipopolysaccharidesHeat-labileHeat StableActively secreted by cells; diffuse into surrounding mediumForm pa of the cell wall; do not diffuse into surrounding mediumReadily separable from cultures by physical means such as filtrationObtained o...
Microbiology
general microbiology
a4fa4c0e-0bf8-4382-9dc9-81c339068c03
The systolic blood pressure of 10 individuals was measured. The mean and median values were calculated to be 130 mmHg and 140 mmHg respectively. What is the shape of the frequency distribution curve?
Symmetrical distribution
Bimodal distribution
Positively skewed distribution
Negatively skewed distribution
3d
single
A negatively skewed distribution is where most of the values are on the higher side and the tail is pointing left. The mean of a distribution is more affected by extreme values than is the median. Therefore, in a negatively skewed distribution with few values on the lower end of the distribution, the mean is pulled tow...
Social & Preventive Medicine
null
306b45b9-f851-4dde-9e41-cd5e4aa1b201
Insal-Salvati index is used for
Olecranon
Patella
Talus
Scaphoid
1b
single
a-length of patellar ligament b-length of patella INSAL-SALVATI index=a/b Normal range is 0.8 -1.2 If ratio increases it suggests patella is at a higher level-PATELLA ALTA If ratio decreases it suggests patella is at a lower level -PATELLA BAHA ref:apley's 9th edition pg no.565
Orthopaedics
Thigh, Knee,Leg,Foot & Ankle injuries
a94974d4-ffea-4ef2-acbe-35e3464b5c72
Which of the following is true about imatinib
It acts by inhibition of tyrosine kinase
It is used to treat GIST
Side effect of imatinib is pedal edema
All of the above
3d
multi
null
Surgery
null
296ad461-b419-4e1f-9e79-8c2fc9a94657
A head injured patient, who opens eyes to painful stimulus, is confused and localizes to pain. What is the Glassgow coma score :
7
9
11
13
2c
single
Answer is C (11): A head injury patient who opens eyes to painfid stimulus (2), is confused (4) and localizes pain (5) has a GCS `Glasgow coma scale' score of 11.
Medicine
null
8b5c9e93-1d6e-4a74-8d02-377884f51cfe
Vitamin D-resistant rickets is associated with all of the following, except
Hypophosphatemia
Increased calcium absorption
Osteomalacia
Osteoporosis
3d
multi
null
Medicine
null
32ac22d6-81a3-427d-a556-c32af0037239
Which is the middle and large carpal bone -
Scaphoid
Pisiform
Hamate
Capitate
3d
single
Ans. is 'd' i.e., Capitate o Among the given options only capitate lies in middle (not lateral or medial) and it is the largest carpal boneo Scaphoid is lateral most bone in proximal row, pisiform is medial most bone in proximal row and hamate is medial most bone in distal row.Carpal bonesProximal Row (Lateral to media...
Anatomy
Osteology of Upper Extremity
8a14882e-69c2-44e2-99c1-511667e23548
Which one of the following is a subcortical dementia?
Alzheimer's disease
Huntington's chorea
Normal pressure Hydrocephalus
Vit B12 deficiency
1b
single
null
Psychiatry
null
2ceae270-cfa7-495b-a0f8-e1757891266d
Severe malnutrition is defined in adults with BMI less than
18.5
16
13
11
1b
single
Body mass index (BMI) BMI = wt (kg)/ ht (m)2 Example: an adult of 70 kg with a height of 1.75 m has a BMI of 70/1.752= 22.9 kg/m2 * BMI is a useful way of identifying under- or over-nutrition but cannot discriminate between lean body or muscle mass and fat mass <img src=" /> Ref Harrison 20th edition pg 76
Medicine
Nutrition
5b48d5da-2c00-428c-85c8-5a75a15806f6
First cell to migrate into a wound due to chemotaxis to sta the process of wound healing is -
Lymphocyte
Macrophage
Platelet
Neutrophil
3d
single
. In healing 1.intial haemorrhage. 2.acute inflammatory response:this occurs withiwithin 24 hours with appearance of polymorphs from margin of incision by the 3rd day polymorphs are replaced by macrophages. Ref Robbins 9 /e pg62-65
Pathology
General pathology
4fc36e3f-57ff-431b-bd32-640ace3a0c71
Most common ovarian tumour in less than 20 year old is:
Epithelial tumour
Germ cell tumour
Metastatic tumour
Sex cord stromal tumour
1b
single
Below 20 years, 60% ovarian tumours are of germ cell origin and in girls less than 105, 85% tumours are of germ cell origin. Ref: Shaw 15th edition: page; 376.
Gynaecology & Obstetrics
null
f19c0643-df6b-4782-a294-70d7dedde24e
Fohergill's repair is also known as :
Khanna's sling operation
Manchester operation
Le Fo's repair
Shirodkar's abdominal sling operation
1b
single
Manchester operation
Gynaecology & Obstetrics
null
90084924-c94b-4541-8eec-83ca03bef490
All of the following are contraindications for rigid esophagoscopy Except
Trismus
Aoic aneurysm
Stricture
None
2c
multi
Regular oesophageal dilatation is done for stricture. Stricture is dilated endoscopically using guidewires. Dilators are solid type with gradual increase in diameters. Dilatation should be done up to minimum 16mm diameter. Reference: SRB's Manual of Surgery, 6th Edittion, page no= 792
Surgery
G.I.T
37a43194-0b5c-4087-a8e2-466750f4dfee
The Pearl index indicates the number of accidental pregnancies per -
1000 population
100 live births
100 women in the age group of 15 to 44 years
100 women years
3d
single
null
Social & Preventive Medicine
null
aa834504-8390-4132-b8c3-31acb3c9454c
Shoening of lower limb with abduction and internal rotation is observed in which of the following types of hip dislocation?
Anterior dislocation
Posterior dislocation
Central dislocation
Lateral dislocation
2c
single
Ans. c. Central dislocation
Surgery
null
e7f9a02e-ce69-4aef-a4bc-d3f8cc4edb67
Acantholysis is characteristic of:
Pemphigus vulgaris
Pemphigoid
Erythema multoforme
Dermatitis herpetiformis
0a
single
A i.e. Pemphigus Vulgaris
Skin
null
80db24b6-3bc5-4ef6-84aa-b934bc122eb6
In cirrhotic ascites, which diuretic is preferred ?
Furosemide
Acetazolamide
Spironolactone
Any of the above
2c
multi
null
Pharmacology
null
80baee15-1dbd-4143-a692-712feb3c74fc
Which of the following peptides are not produced by the renal system?
Renin
Angiotensin I
Erythropoietin
1,25DHCC
1b
single
The hormones produced in the kidneys are 1,25 Dihyrocholecalciferol, Renin and Erythropoetin. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an impoant role in the renin-angiotensin syst...
Physiology
null
906a2759-988e-4a96-8b5d-6c43df60204d
All of the following drugs act by blocking calcium channels except:
Dantrolene
Nicardipine
Diltiazem
Verapamil
0a
multi
null
Pharmacology
null
a223166e-c26f-480b-9450-980a9395053f
Bone marrow depression is seen with chronic administration of
Isoflurane
N2O
Ether
Halothane
1b
single
(Refer: Morgan and Mikhail's Clinical Anaesthesiology, 5th edition, pg no.163-168)
Anaesthesia
All India exam
9d8662a8-555d-451d-8314-b4058a55534e
Which of the following statements about imipenem is most accurate?
The drug has a narrow spectrum of antibacterial action
It is used in fixed dose combination with sulbactum
In renal dysfunction, dosage reductions are necessary to avoid seizures
Imipenem is active against methicillin-resistant staphylococci
2c
multi
Carbapenems are synthetic b-lactam antibiotics Imipenem, meropenem, doripenem and eapenem are the drugs of this group currently available. Imipenem : Effective against : Gm +ve, Gm -ve including pseudomonas and anaerobic. Dehydropeptidase by kidney metabolises imipenem rapidly. Cilastatin is a dehydropetidase inhibitor...
Pharmacology
Cell Wall Synthesis Inhibitors
08866dee-aa08-4f9d-801c-e5fd8bd83180
The true statement about contrast induced acute kidney injury is:
Rise in the serum creatinine after 12 hours
Peak in serum creatinine in 2 weeks
Dialysis requirement is usually uncommon
High fractional excretion of Na is a common finding
2c
multi
Iodinated contrast agents are a leading cause of AKI. Increased risk is seen in Chronic kidney disease - paicularly diabetic nephropathy The most common clinical course of contrast nephropathy is A rise in SCr beginning 24-48 hours following exposure Peaking within 3-5 days Resolving within 1 week ALSO NOTE: More sever...
Medicine
null
4867e63b-976b-461d-b36e-f4f7a7e03119
A pt. presents with hematuria of several days and dysmorphic RBC casts in urine. The site of origin is -
Kidney
Ureter
Bladder
Urethra
0a
single
null
Surgery
null
c4920168-0531-41d2-85fa-d66ff3019bf1
Which Fully humanized antibody is used in treatment of rheumatoid ahritis?
Anakira
Adalimumab
Infliximab
Leflunomide
1b
single
MUMABs- are fully humanized monoclonal antibodies Omabs- derived from mice Zumabs- 80 % Human Adaliimumab: This recombinant monoclonal anti-TNF Antibody is administered s.c. 40 mg every 2 weeks. Injection site reaction and respiratory infections are common adverse effects. Combination with Mtx is advised to improve the...
Pharmacology
Immunomodulators
6641a440-cdc6-482e-8d60-6c14e3a8abbb
The drug of choice for mushroom poisoning-
Adrenaline
Physostigmine
Atropine
Carbachol
2c
single
Ans. is 'c' i.e., Atropine Mushroom poisoning o Depending on the toxic principal present in the paicular species, at least 3 types of mushroom poisoning is known. 1. Muscarine type (early mushroom poisoning) Due to Inocybe and related species. Symptoms are due to muscarinic action. T/t of choice is atropine. 2. Halluci...
Pharmacology
null
d656a5a0-e620-4b57-826e-6a6b9b616ccb
Prerequisite for applying forceps are all except: September 2007
Aftercoming head of breech
There should be no CPD
Saggital suture should be in line with transverse diameter of pelvis
Foetal head should be engaged
2c
multi
Ans. C: Saggital suture should be in line with transverse diameter of pelvis Conditions to be fulfilled prior to forceps operation: The fetal head must be engaged Cervix must be fully dilated Membranes must be ruptured The position and station of the fetal head must be known No major CPD Adequate analgesia Bladder must...
Gynaecology & Obstetrics
null
10f7126b-41ba-4203-a3b0-9ff62b84165e
Amino acid involved in urea synthesis:
Glutamine
Aspaic acid
Valine
Phenylalanine
1b
single
Ans:B.)Aspaic Acid Urea has 2 amino (-NH2) groups, one derived from NH3 and other from aspaate.UREA CYCLE* Location: Cytosol and mitochondria of hepatocytes.* Substrates: NH 3 (as derived from oxidative deamination of glutamate); CO2 ; aspaate; three ATP.* Products: Urea; fumarate; H2O.* Purpose: The urea cycle allows ...
Biochemistry
null
775d2fd7-ae83-47e5-bfde-0131edf1a2b8
All are causes of pulmonary hypertension except-
Hyperventilation
Morbid obesity
High altitude
Fenfluramine
0a
multi
null
Medicine
null
a36597d8-c8b2-4eec-b36c-8c91c04ab87d
Current mode of analgesia best for intrapartum pain relief:
Epidural analgesia
Spinal anaesthesia
Inhalational
Local analgesia
0a
single
Ans. a (Epidural analgesia)LUMBAR EPIDURAL ANALGESIAIndications for lumbar epidural analgesia :# Pain in labor, management of the patient with preeclampsia who does not have a coagulation abnormality, management of labor in patients with certain cardiac lesions, and management of breech delivery.# Of the various pharma...
Anaesthesia
Local and Regional Anesthesia
84f81388-d7d7-4ab5-a651-d496c4c0e120
28 weeks pregnancy with abdominal pain and fever. Ultrasonographic examination shows presence of fibroid. What is the next line of management-
Hysterectomy
Conservative management
Termination
Myomectomy
1b
single
Ans. is 'b' i.e., Conservative management o The presence ofpain and fever in a female in her mid pregnancy with ultrasound examination showing presence offibroid supports the diagnosis of red degeneration.Red Degeneration (Also known as Carneous Degeneration)o Occurs in pregnant females with presence of fibroid because...
Gynaecology & Obstetrics
Treatment and Recurrence
edd890f2-bd51-40c8-8d94-d2c8b46c5444
Which of the following is seen at high altitude:September 2011
Low PaO2
High PaO2
Normal PaO2
High PaCO2, Low PaO2
0a
single
Ans. A: Low PaO2With increasing altitude, barometric pressure decreases, so the total pressure of the air decreases and pH2O and pCO2 remains constant So p02 and pN2 decreases progressively with heightHigh-altitude illnessUsually occurs at altitudes of over 1,500 m (4,921 ft)Caused primarily by hypoxia but is compounde...
Physiology
null
c5bab489-5b35-4aee-a8c5-ea00f672d3fc
In a child presenting with obstructive jaundice all are seen except
Gamma glutamyl transpeptidase
Alkaline phosphatase
Glutamate dehydrogenase
5' Nucleotidase
2c
multi
.lab investigations in obstructive jaundice gamma glutamyl transpeptidase:>50IU/L Serum bilirubin:>1mg%direct is increased serum albumin globulin ratio prothrombin time serum alkaline phosphatase,SGOT,SGPT,5&;nucleotidase ERCP TLC BAILEY AND LOVE&;S SHO PRACTICE OF SURGERY,24 th edition, PG NO:696
Pediatrics
Gastrointestinal tract
bae9624c-04f3-4ab0-a897-baef27f86a82
Most common renal pathology in shock:
Acute tubular necrosis
Acute cortical necrosis
Renal vein thrombosis
Acute medullar necrosis
0a
single
Ans: a
Medicine
Kidney
c69fad1c-f13a-441f-b7f9-e28054049ac3
Which of these features is a classic radiologic feature of optic nerve glioma:
Tram-track appearance of optic nerve
Kingking of optic nerve
Multiple cystic spaces in optic nerve
Adjacent bony erosion
1b
single
Ans. Kingking of optic nerve
Ophthalmology
null
625642a5-f65d-402f-b067-2abda34f6e6a
Treatment of Advanced Proliferative Diabetic Retinopathy with extensive vitreoretinal fibrosis and tractional retinal detachment involves all of the following except.
Reattachment of detached or torn retina
Removal of epiretinal membrane
Vitrectomy
Exophotocoagulation
3d
multi
D i.e. Exophotocoagulation Treatment of advanced proliferative diabetic retinopathy with vitreoretinal fibrosis and tractional rectinal detachment involves previtrectomy pan retinal endophoto coagulation (not exophotocoagulation)Q, vitrectomy (pars plana or posterior route), reattachment of detached or torn retina and ...
Ophthalmology
null
2deecdc0-4f6b-40c9-b3dd-f3c1bbbc7423
Deficiency in globin synthesis
Thalassemia
Sickle cell disease
Hereditary spherocytosis
None of these
0a
multi
Ans. is 'a' i.e., ThalassemiaThalassemia Syndromes :?The thalassemia syndromes are a heterogeneous group of disorders caused by inherited mutations that decrease the synthesis of either the a-globin or (3-globin chains that compose adult hemoglobin, HbA (a2(32), leading to anemia, tissue hypoxia, and red cell hemolysis...
Pathology
null
ab84cb77-ab48-48dd-b078-2b5d50596fee
A alcoholics addicted presents in emergency with irrelevant talking & disoriented to time, place and person there is H/O not taking alcohol from last 3 days & no head injury. He also have visual hallucination. The diagnosis?
Dementia praecox
Delirium tremens
Schizophrenia
Korsakoff psychosis
1b
multi
B i.e. Delirium tremens
Psychiatry
null