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135
80743579-7b0b-4df2-a10a-04e4f2311aa7
A thirty year man presented with nausea, fever and jaundice of 5 days duration. The biochemical tests revealed a bilirubin of 6.7 mg/dl (conjugated 5.0 mg/dl) with SGOT/SGPT (AST/ALT) of 1230/ 900 IU/ml. The serological tests showed presence of HBsAg, IgM anti HBc and HBe Ag. The most likely diagnosis -
Chronic hepatitis B infection with high infectivity
Acute hepatitis B infection with high infectivity
Chronic hepatitis B infection with low infectivity
Acute hepatitis B infection with low infectivity
1b
single
null
Microbiology
null
320ab1f4-4aa3-4da3-b174-c7c89e6d6230
In computed tomography (CT), the attenuation values are measured in Hounsfield units (HU). An attenuation value of '0' (zero) HU corresponds to:
Water
Air
Very dense bone structures
Fat
0a
single
Ans. Water
Radiology
null
1fb4d597-8906-45b2-89e9-f586da6fae63
SSRI is first line treatment for :
OCD
Panic disorder
Social phobia
All
3d
multi
Ans:D.)All Selective serotonin reuptake inhibitors (SSRIs) are US-FDA approved drugs of first choice (line) for major Depression, Obscessive - compulsive disorder (OCD), Premenstrual dysphoric disorder, Post traumatic stress disorder (PTSD), Panic disorder, Eating disorder (bulimia nervosa), and Social phobia (social a...
Psychiatry
null
392f4faa-d522-4586-b288-0a5d691f04b9
Mees lines are characteristic of which poisoning?
Phosphorus
Arsenic
Lead
Thalliam
1b
multi
Mes line(Aldrich mees line) are very charactristic of Arsenic poisoning.They are white bands of opacity in the nails of fingers and toes.
Forensic Medicine
null
a67a0110-ea4a-49a7-b0f2-8deba91f86ab
Glutamic acid is formed from which of the following amino acid?
Threonine
Proline
Alanine
Lysine
2c
single
Glutamic acid is formed by the transamination of alanine and vice versa. Alanine aminotransferase is the enzyme and pyridoxal phosphate is the coenzyme.Ref: DM Vasudevan - Textbook of Biochemistry, 7th edition, page no: 201, fig.15.8.
Biochemistry
Metabolism of protein and amino acid
d182c30f-06a5-4d0a-9f0b-a1b5e0254767
Which disease comes under International Surveillance?
Typhoid fever
Salmonellosis
Chikungunya fever
Hepatitis B
1b
single
Diseases under WHO surveillance Polio Rabies Relapsing fever Influenza Salmonellosis Malaria Louse born typhus Ref : Park's Textbook of Preventive and Social Medicine; 24th edition
Social & Preventive Medicine
Concept of health and disease
a85db1d4-b089-4fc1-af3b-a5c6ab715ebe
Coenzyme used in Kreb's cycle ?
NAD
NADP
NADPH
NADH
0a
single
Niacin is used as coenzyme nicotinamide adenine dinucleotide (NAD') for transfer of hydrogen.
Biochemistry
null
52cd5175-0cc3-4176-8f64-90ef08fefd33
Apolipoprotein activating L-CAT (LQ) is
B - 48
A - I
A - II
B-100
1b
single
A-1 is the integral apoprotein of HDL.LCAT binds to discoidal HDL activated by A1 conves discoidal HDL to HDL 3Harpers Biochemistry; 30th edition
Biochemistry
Metabolism of lipid
ccd9d635-f050-4da3-9fa6-56249b61d43a
B-type tympanogram is seen in -
Serous otitis media
Ossicular discontinuity
Otosclerosis
All of the above
0a
multi
Ans. is 'a' i.e., Serous otitis media Type of curseConditionA curve (Normal peak height and pressure)NormalEustachian tube obstructionAs curve (It is also a variant of normal tympanogram but may be shallow)OtosclerosisTumors of middle earFixed malleus syndromeTy mpanosclerosi sAd curve(Variant of normal with high peak)...
ENT
Ear
42b701a2-2fba-46bf-ba6e-428f68796c70
In adults, circulatory collapse occurs after a minimum of what percentage burns of total body surface area: NIMHANS 08; TN 11
5%
10%
15%
20%
2c
single
Ans. 15%
Forensic Medicine
null
a9ddd372-4af2-4aff-b9c2-50d296a6d368
What passes through diaphragm at T12 level ?
Esophagus
IVC
Thoracic duct
Phrenic nerve
2c
single
Ans. is 'c' i.e., Thoracic duct
Anatomy
null
72f55aa7-5242-4823-80dd-078c86964a1e
Beri-Beri is caused by -
Thiamine
Folic acid
Riboflavin
Niacin
0a
single
- beri beri is due to the deficiency of thiamine. - it has 3 main forms. Dry form characterised by nerve involvement. Wet firm characterised by hea involvement and infantile beri beri. Reference : Park's textbook of preventive and social medicine, 23rd edition, pg no:618 <\p>
Social & Preventive Medicine
Nutrition and health
bdc6cc31-cae1-4f47-9e81-d15797979283
A 58 year old male presents with hematuria. He s diagnosed of having bladder cancer which extends muscle deep. The best treatment is
Intravesical Chemotherapy
Neoadjuvant chemotherapy followed by radical cystectomy
Radiotherapy
Tranurethral resection
1b
single
Answer- B. Neoadjuvant chemotherapy followed by radical cystectomy
Surgery
null
b769362b-ea8c-4d85-87ff-a24724277a31
The condition in which patient present with normal leucocyte count or less than normal and shows WBC in the peripheral blood:
Aleukemic Leukemia
Subleukemic leukemia
Acute leukemia
Chronic leukemia
0a
single
null
Medicine
null
106d53c8-ff8d-4e36-8ddd-b945d34f3de4
The most common cause of a pleural effusion is
Cirrhosis
Left ventricular failure
Pulmonary embolism
Pneumonia
1b
single
The most common cause of pleural effusion is left ventricular failure. Pleural effusions occur in hea failure when there are increased hydrostatic forces increasing the pulmonary interstitial fluid and the lymphatic drainage is inadequate to remove the fluid.Right-sided effusions are more common than left-sided effusio...
Microbiology
All India exam
7b48008c-80f5-4d6b-be71-0abe857dc31c
M/c cause of chronic laryngeal stenosis ?
Trauma
TB
Wegeners
Tumor
0a
single
Ans. is 'a' i.e., Trauma Laryngeal stenosis (LS) is a congenital or acquired narrowing of the larynx causing airway compromise. The acquired causes may be due to endotracheal intubation, trauma, burns, inflammation, neoplasms, autoimmune disorders and collagen vascular disease.
ENT
null
b4814935-96ed-49a2-9b76-0072069b8292
Child knows his/her sex at the age of:
1 year
3 years
5 years
7 years
1b
single
A child knows her full name and gender by the age of 3 years.
Pediatrics
Social and Language Milestones
4ee59051-7c07-46df-ab93-49ca6d608e76
Early stage of trauma is characterized by
Catabolism
Anabolism
Glycogenesis
Lipolysis
0a
single
Injury Phase (Phase of catabolism):-- Begins at the time of injury and lasts for 2-5 days-- Phase of hypermetabolism-- Stress hormones (coisol, catecholamines and glucagon) and volume control hormones (renin-angiotensin, aldosterone and ADH) are increased. This leads to proteolysis, lipolysis, hyperglycemia and wound h...
Surgery
Trauma
4456e5b2-9887-434f-8f27-e0f5e9a330de
Example for Denticulate suture
Internasal suture
Coronal suture
Lambdoid suture
Parietotemporal suture
2c
single
Types of sutures:Plane: Internasal sutureSerrate: Coronal sutureDenticulate: Lambdoid sutureSquamous: Parieto-Temporal sutureReference: Chourasia; 6th Edition; 4th page
Anatomy
General anatomy
432865e6-cbb2-40ed-9a93-84760fe5da35
A 29-year-old female diagnosed with AIDS has been suffering from a progressive blurring of vision in her right eye. On funduscopic examination, a small white opaque lesion is noted on the retina of her right eye. Which of the following is the most appropriate therapy for this patient?
Acyclovir
Amantadine
Flucytosine
Ganciclovir
3d
multi
This patient is most likely suffering from cytomegalovirus (CMV) retinitis. The best drug treatment for this infection is ganciclovir. Acyclovir is not effective in CMV infections. It is used more for HSV type 1 and 2 infections. Amantadine is used either therapeutically or prophylactically for the influenza A virus. F...
Microbiology
null
458239ed-e5e5-4f12-bc31-848ac81d2fd3
Denominator of MMR if MMR is expressed as 167 is:-
Per 100000 live births
Per 1000 total birth
Per 10000 total birth
Total number of women of reproductive age group in the population
0a
single
Ans. is 'a' i.e. 1000 live births It's a ratio: Denominator is Per 100000 live births. It will be rate : if the denominator is reproductive women. But still some books write it as rate. But in Park it's clearly differentiated. The data we express MMR as 167 is a ratio.
Social & Preventive Medicine
Obstetrics
bf199fef-d8ed-48de-b510-837e5dc8cadf
Kamli Rath 75 yrs old woman present with post-myocardial infarction after 6 weeks with mild CHF. There was past H/O neck surgery for parathyroid adenoma 5 years ago, EKG shows slow atrial fibrillation. Serum Ca+2 13.0 mg/L and urinary Ca2+ is 300 mg/ 24 hr. On examination, there is small mass in the Para tracheal posi...
Repeat neck surgery
Treatment with technetium - 99
Observation and repeat serum Ca+2 in two months
Ultrasound-guided alcohol injection of the mass
3d
multi
This patient operated previously for parathyroid adenoma, is having recurrent hyperparathyroidism. In the setting of recent myocardial infarction, CHF and atrial fibrillation, any operation carries a high risk. Furthermore, an operation on a previously operated neck is quite difficult. Alcohol ablation of the mass with...
Surgery
null
3858506b-a4de-4902-8dd4-7dbcb6229dbf
Polyariticular rheumatoid ahritis is diagnosed when more than............. Joints are involved
One
Two
Four
Five
3d
single
The initial pattern of disturbution of joint involvement may be monoaicular,oligoaicular(less than 4 joints),or Polyariticular (,greater than 5 joints ) usually on a symmetric distribution Ref, :Robbins page no 1209 8th edition
Anatomy
Musculoskeletal system
54b334c8-07f4-47ea-a320-12eb9f201180
A 56-year-old woman with a history of breast cancer that was treated 5 years ago with lumpectomy and radiation but with no chemotherapy returns with bone pain, fatigue, and weakness. A complete blood count reveals severe anemia, as well as decreased white blood cells and platelets. Examination of a peripheral blood sme...
chloramphenicol.
Diphyllobothrium latum infestation.
megaloblastic anemia.
myelophthisic anemia.
3d
multi
- Infiltration of tumor cells from cancers, those of breast & prostate - displaces bone marrow elements, thereby causing myelophthisic anemia. OTHER OPTIONS: - Chloramphenicol causes aplastic anemia in some individuals. - Diphyllobothrium latum infestation can result in megaloblastic anemia due to vitamin B12 deficienc...
Pathology
Hematopoeisis: Basic concepts
9dd4a0f1-3e68-48f5-8ea3-9c96505ef8c2
Which is the first permanent tooth to erupt ?
Canine
Molar
Incisors
Premolar
1b
single
First and the last tooth to erupt in permanent dentition is Molars.
Forensic Medicine
null
479cc91e-7fda-48cc-a5f0-8607756a620a
The limit of loudness (expressed as decibels) that workers can tolerate without substantial damage to their hearing, during their work hours, is:
55
65
75
85
3d
single
A noise of 90 dB (A) SPL, 8 hours a day for 5 days per week is the maximum safe limit as recommended by Ministry of Labour, Govt. of India-Model rules under Factories act Noise induced hearing loss Hearing loss can result from damage to structures or nerve fibers in the inner ear that respond to sound. This type of hea...
ENT
null
ea7ba72f-8a5b-4e72-9086-6543d51173f4
Among the following the least common cause of acute upper GI bleeding is?
Mallory Weiss tear
Ulcer
Varices
Vascular ectasia
3d
multi
Source of bleeding Propoion of patients, % Ulcers 31-67 Varices 6-39 Mallory Weiss tears 2-8 Gastroduodenal erosions 2-18 Erosive esophagitis 1-13 Neoplasm 2-8 Vascular ectasia 0-6 No source identified 5-15
Medicine
Bleeding from the GUT and diseases of esophagus
0f277307-23ec-4f1b-aca5-eac0765a3fa5
HHV-6B causes -
Carcinoma cervix
Carcinoma endometrium
Clear cell carcinoma
Focal encephalitis
3d
single
HHV 6B is the cause of mild but common childhood illness exanthem subitum. In older age groups ,it has been associated with infectious mononucleosis syndrome,focal encephalitis and in the immunodeficient,with pneumonia and disseminated disease. REF:ANATHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 8TH EDITION PAGE N...
Microbiology
Virology
79abf7b1-69e7-4fcc-a952-763a6661ba44
Anatomical structure injured in excision of ranula -
Lingual vein
Lingual artery
Submandibular duct
Parotid duct
2c
single
null
Surgery
null
c82ed37e-c89d-416e-8cbc-6c57c8fe1968
Which of the following findings is suggestive that ovulation has taken place?
Pseudostratification in endometrium
Presence of Spinnbarkeit Phenomenon in cervical mucous
Sudden reduction in size of follicle and free fluid in Pouch of Douglas on USG
Trilamilar endometrium on USG
2c
single
Endometrial biopsy Early secretory Subnuclear vacuolation (Ist HPE evidence of progesterone secretion) Seen on D16 of cycle Nuclei of glands gone up Stromal edema Late secretory Toous/ coiled glands All secretions in lumen of gland Cork screw glands( on D20 of cycle) Max stromal edema seen around D22of cycle) HPE of Pr...
Gynaecology & Obstetrics
Tests of Ovulation
b47511f8-1071-4c03-bb03-ad8f1ddbe67a
Sedative with GABA facilitating action but without anticonvulsant and muscle relaxant propeies and no effect on sleep ?
Diazepam
Zolpidem
Phenobarbitone
Buspirone
1b
single
Ans. is 'b' i.e., Zolpidem Among the given options, three are sedative-hypnotic with GABA facilitatory action - Diazepam (a benzodiazepine) - But it also has anticonvulsant and muscle relaxant propey. it) Phenobarbitone - But it has anticonvulsant propey. Zolpidem Has no anticonvulsant and muscle relaxant propey and ha...
Pharmacology
null
ed92f823-56fd-4381-b2a3-a061921084ac
First branch of Facial nerve is:
Nerve to stapedius
Chorda tympani nerve
Greater petrosal nerve
Lesser petrosal nerve
2c
single
Ans. C. Greater petrosal nerveFacial nerve is the 7th cranial nerve. It is a mixed (i.e., motor and sensory) nerve, but predominantly it is motor. It is named facial nerve because it supplies the muscles of facial expression.Branchesa. Greater petrosal nerve--arises from the geniculate ganglion. It is the first branch ...
Anatomy
Head & Neck
3b7b57b8-3c7d-4020-ac31-7020d9bc40e3
The demographic goal of Net Reproduction Rate is equal to one (NPR=1) can be achieved only if the Couple Protection Rate exceeds
40%
50%
60%
70%
2c
single
(C) 60%[?]Couple protection rate (CPR)oCouple protection rate (CPR) is an indicator of the prevalence of contraceptive practice in the community.oIt is defined as the per cent of eligible couples effectively protected against childbirth by one or the other approved methods of family planning, viz. sterilization, IUD, c...
Social & Preventive Medicine
Demography and Family Planning
66953b23-4e19-43a9-9e9f-a04197e66001
Paraneoplastic syndrome associated with RCC are all of the following, except:
Polycythemia
Hypercalcemia
Hypeension
Cushing syndrome
3d
multi
RCC is associated with wide range of paraneoplastic syndromes, ? Erythrocytosis (polycythemia ? Hypercalcemia ? Hypeension ? Non metastatic hepatic dysfunction Cushing syndrome is rarely seen in RCC. Ref: Emil A. Tanagho, Jack W. McAninch, (2004), Chapter 21, "Renal paranchymal neoplasm", In the book, "Smith's General ...
Pathology
null
8288456d-7f27-427a-9284-d9751fa73ca8
Red flag sign in child development if not attained by __________
No single word at 18 month
Not able sit with unsuppoed by 12 months
Not walking alone by 18 month in boys
All of the above
3d
multi
Red Flags in Developmental Screening and SurveillanceThese indicators suggest that development is seriously disordered and that the child should be promptly referred to a developmental or community pediatrician. Note: Most children do not have "red flags" and thus require quality screening to detect any problems. POSIT...
Pediatrics
Growth and development
79a81298-e728-4081-b2b5-be965d210d7d
Michaelis Menten Hypothesis states that
Rate of enzymatic reaction is independent of substrate concentration
Rate of non enzymatic reaction is proportional to substrate concentration
Km is the enzyme substrate complex association constant
Enzyme substrate complex formation is essential in enzymatic reaction.
3d
single
Michaelis-Menten Theory (Enzyme-Substrate Complex Theory) Enzyme combines with a substrate to form a transient Enzyme-Substrate Complex which immediately break into Enzyme and products.
Biochemistry
null
d0c98786-10d6-447a-967d-5c49376dd1d7
Function of Ig A is -
Acts as a mucosal barrier for infection
Circulating antibody
Kills virus infected cells
Activates macrophages
0a
single
Question repeated
Microbiology
Immunology
77db5401-a696-42c9-bbf6-136649ebe489
Glycolytic enzymes(s) inhibited by Fluoride:
Hexokinase
Aldolase
Enolase
Pyruvate kinase
2c
single
Inhibitors of Glycolysis: Inhibitors of Glycolysis Enzyme Inhibited Iodoacetate Glyceraldehyde - 3 - P Dehydrogenase Arsenate Glyceraldehye - 3 - P Dehydrogenase Sodium fluoride Enolase Oxamate Lactate Dehydrogenase
Biochemistry
Glycolysis
a2a4182e-7356-4270-88e8-40626e40a414
A patient is to undergo angiography for unstable angina. His routine evaluation revealed his serum creatinine to be elevated. All of the following can be used to prevent contrast nephropathy, EXCEPT:
Haemofiltration
Fenoldopam
N-acetylcysteine
1/2 N saline
1b
multi
Strategies for the Prevention of Contrast-Induced Nephropathy: Strategies that do not work: Mannitol Furosemide Dopamine Atrial natriuretic factor Fenoldopam Hemodialysis Strategies that may work: Calcium channel blockers Theophylline N-Acetylcysteine Hemofiltration Sodium bicarbonate Ascorbic acid Iso-osmolar contrast...
Radiology
null
43044984-b711-4102-87e9-2a6b578e2699
A lady wants LASIK surgery for her daughter. She asks for your opinion. All the following things are suitable for performing LASIK surgery except –
Myopia of 4 Diopters
Age of 15 years
Stable refraction for 1 year
Corneal thickness of 600 microns
1b
multi
Patient selection criteria for LASIK Patients above 20 years of age Stable refraction for at least 12 months Motivated patients Myopia up to -12D The absence of corneal pathology Corneal thickness > 500 m ​Contraindications of LASIK Monocular patient Infections eg: conjunctivitis Glaucoma Autoimmune disease Thin cor...
Ophthalmology
null
ffc2ba0a-f6c2-43fa-8000-cdc6ba408267
Cardiac index is the ratio of?
Cardiac output and body weight
Cardiac output and surface area
Cardiac output and work of hea
Surface volume and surface area
1b
single
Cardiac index is the cardiac output corrected for the individual's size. For example, the cardiac output of a 50-kg woman will be significantly lower than that of a 90-kg man. It has been found, however, that cardiac output correlates better with body surface area than with body weight. Therefore, it is common to expre...
Physiology
null
c93bf9ab-61b8-41a4-91c8-1b6e6a5303d5
Carcinoma cervix involving upper 2/3rd of vagina. The stage would be: September 2009
Stage II a
Stage II b
Stage III a
Stage III b
0a
single
Ans. A: Stage II a
Gynaecology & Obstetrics
null
a5b933d5-3c15-4e19-8d5f-5c814440c9f0
An 18-year-old pregnant woman receives no prenatal care, eats a diet containing mostly carbohydrates and fats, and does not take prenatal vitamins with iron. She feels increasingly tired and weak during the third trimester. The infant is born at 35 weeks' gestation and is listless during the first week of life. Laborat...
Dermatitis
Diffuse goiter
Microcytic anemia
Peripheral neuropathy
2c
multi
Iron deficiency, which gives rise to microcytic anemia, is common in women of reproductive age because of menstrual blood loss and in children with a poor diet. During pregnancy, women have greatly increased iron needs. Low serum ferritin is indicative of iron deficiency. Dermatitis can be seen in pellagra (niacin defi...
Pathology
Environment & Nutritional Pathology
4f4ac24a-6f3a-4adc-a347-2fde996cae72
Not a cause of Roth spots?
Leukemia
Severe anemia
SLE
Hypersensitivity pneumonitis
3d
single
Roth spots Round retinal hemorrhages with white centers Seen in : Infective endocarditis SLE Serum sickness Polyaeritis nodosa Severe anemia Leukemia Prolonged anesthesia
Medicine
Rheumatic Hea disease & infective endocarditis
dc3d07b8-2ade-4e3a-a868-5367d7bcf067
Which of the following is not true about the mechanism of action of benzodiazepines?
Acts on mid brain, ascending reticular formation and limbic system
It exerts effects through the GABA A receptors
It increases conductance of Cl- channels
It has GABA mimetic action
3d
multi
Ans. is 'd' i.e., It has GABA mimetic action Mechanism of action of benzodiazepines (BZDs)* Muscle relaxation is produced by action on medulla.* Ataxia is due to action on cerebellum.* BZDs acts on GABAA receptors.* GABAa receptor has 5 subunits a / b, b, a / g.* GABA binding site is on b. subunit, while BZDs binding s...
Pharmacology
C.N.S
d28eda9d-c7c7-4a84-80b1-6a57e3d3661b
Following are the findings in sickle cell Anemia, except -
Fish vertebra
Enlarged heart
Splenomegaly usually seen
Leukocytosis
2c
multi
Splenomegaly is found in the early stage of sickle cell anemia. By continued infarction and hypoxia leads to progressive scarring and shrinkage of the spleen, so that by adolescent or the adulthood, only a small nubbin of fibrous tissue may be left; this is called autosplenectomy. Bone changes in sickle cell anemia are...
Pathology
null
fce245e5-d5db-4965-8c3c-cb0f4141ffe3
Which of the following conditions does not have a National Screening/Control Programme?
Diabetes Mellitus
Dental caries
Refractive errors
Carcinoma cervix
1b
single
Ans. is 'b' i.e. Dental caries o No National programme for oral health is under implementation. About other options o There is Pilot Programme for prevention & control of DM. CVD and deafness. o The National Programme for control of blindness includes screening for refractive errors. o Cervical cancer screening program...
Social & Preventive Medicine
null
faf871b0-801d-4561-84c8-0a20b3aeac7e
Which of the following contains sulphur?
Creatine
Insulin
Inulin
Creatinine
1b
single
Ans: b (Insulin) Ref: Harper, 25th ed, p. 347,115Insulin is a polypeptide consisting of two chains linked by two inter chain di sulphide bridges.Amino acids required for special products:> Creatine - glycine + arginine+ methionine> Glutathione - glycine + cysteine + glutamate> Purine - glycine + aspartate + glutamine +...
Biochemistry
Proteins and Amino Acids
44385d4e-be54-4e51-9011-f6fc395c7784
Which one of the following is the management of pancreatic abscess -
Needle aspiration
Gastro-cytostomy
External drainage
Jejuno-cystostomy
2c
single
null
Surgery
null
0c4b30b7-5c22-429c-a5ab-05074aeb5dac
Sentinel lymph node biopsy is done in all except
ca breast
ca penis
malignant melanoma
ca colon
3d
multi
null
Surgery
null
2c8b4eb9-743d-4d34-afa8-bac38347065d
During pregnancy the maternal blood volume increases by nearly :
5 - 10%
15 -- 20%
50%
70%
2c
single
Ans. is c i.e. 50% Friends, we have dealt with hemodynamic changes during pregnancy in detail earlier but here lets quickly revise a few changes asked quite often. Most impoant physiological changes during pregnancy (for 11th hour revision) Net weight gain in pregnancy is 11 kg (24 lb).deg Blood volume T's by 40-50%.de...
Gynaecology & Obstetrics
null
6ea437a5-7dd2-4909-85f8-c94745c3c296
Side effect of MgSo4 used in the treatment of eclampsia is
Hypotension
Polyuria
Coma
Pulmonary edema
3d
single
Complications : Pulmonary edema Anuria Hea failure Hyperpyrexia Psychosis Ref: Dutta Obs 9e pg 222.
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
8cf31e07-9e63-4edd-ac3c-e4179774fea1
True about Ischiorectal fossa Boundaries
Anterior border is formed by inferior fascia of urogenital diaphragm.
Superior border is formed by Gluteus Maximus
Lateral border is formed by Levator Ani
Posterior border is formed by obturator internus muscle.
0a
multi
Ans. (a) Anterior border is formed by inferior fascia of urogenital diaphragm.Ref: IB singh Anatomy 2nd ed. / fig. 25.12ANTERIOR* Fascia of Colles covering the Transversus perinea superficialis* Inferior fascia of the urogenital diaphragmPOSTERIOR* Gluteus maximus* Sacrotuberous ligamentLATERAL MEDIAL* Levator ani* Sph...
Surgery
Rectum
c32d489e-460b-4e30-a793-52cc30363063
Hypehyroidism will present as all, except :
Hypotension
Atrial fibrillation
Tremor
Panic attacks
0a
multi
Hypehyroid symptoms include heat intolerance, increased sweating and thirst, and weight loss despite adequate caloric intake. Symptoms of increased adrenergic stimulation include palpitations, nervousness, fatigue, emotional lability, hyperkinesis, and tremors. The most common GI symptoms include increased frequency of...
Surgery
null
512ce60e-6c09-417d-91b3-e1d2f0d539b6
A patient presents in the causality with history of abdominal pain. On examination the person is in shock, with severe abdominal tenderness and guarding. There was also one episode of bloody diarrhoea. He gives a history of recurrent abdominal pain soon after taking food which persists for about 3 hours after food. He ...
Acute thrombotic mesenteric vascular occlusion
Acute pancreatitis
Acute duodenal ulcer perforation
Acute appendicitis
0a
single
The person has had recurrent episodes of abdominal angina as shown by the pain after food intake. He also has a history of MI which also suggests that he has atherosclerosis. The bloody diarrhoea is again suggestive of mesenteric vascular occlusion in this patient. Ref: Manipal Millennium Edition, Page 429; S.Das, Edit...
Surgery
null
31eb4e7f-b538-4d8d-9bfb-82533c0f311a
Fick principle of calculation of cardiac output doesn't depend on-
Whole body oxygen consumption
Oxygen content of arterial blood
Stroke volume
Oxygen content of venous blood
2c
single
Based on Fick principle
Physiology
null
55848125-05f7-43c4-8dba-74307c7c7964
Example of type 4 hypersensitivity is:
Serum sickness
Granulomatous reaction
Schwazman reaction
Ahus reaction
1b
single
Ans. b. Granulomatous reaction
Microbiology
null
ea048cfb-76c4-4754-a0c7-9aedc52664c2
A boy presented with prolonged jaundice, constipation and umbilical hernia. what is the probable diagnosis?
Growth hormone deficiency
Kernicterus
Congenital hypothyroidism
Congenital adrenal hyperplasia
2c
single
Prolonged jaundice, constipation, Umbilical hernia are all seen in congenital hypothyroidism.
Pediatrics
null
b5aaeee7-5be6-46c8-b25f-62124b9313d9
Osteosarcoma can arise from:
Diaphysis
Epiphysis
Metaphysis
All of the above
2c
multi
Ans. c (Metaphysis). (Ref. to Radiology Review Manual, 5th/138; Essential orthopedics by Maheshwari 2nd/218)OSTEOSARCOMA* It is 2nd most common 1deg malignant tumor of bone (after multiple myeloma). Peak incidence in menl0-20 years of age. * It has bimodal age distribution: 10-25 years and > 60 years with M:F = 3:2 to ...
Orthopaedics
Bone Tumour
5a2a4115-f381-4d10-a3ab-9ca6da93e27f
Episodic hypeension is a feature of
Carcinoid tumor
Insulinoma
Pheochromocytoma
Zollinger-Ellison syndrome
2c
single
Classic triad: Headache + Diaphoresis+ Palpitation
Physiology
All India exam
81fbc82a-d070-4b72-a17a-a87b947c848a
Acantholysis is:
Lysis of basale cell layer
Separation of keratinocytes
Thickening of granular layer
Thickening of corneum layer
1b
single
Ans. (b) Separation of keratinocytesRef: Harrison 19th ed. / 370* Keratinocytes are connected to one another by intracellular desmosomal bridges.* If there is loss of these desmosomal bridges, it will lead to separation of keratinocytes and the condition is known as acantholysis.* If separation continues, there will be...
Skin
General
565bc834-8a9d-497d-b30b-a72798a5265d
High risk of malignancy is seen in?
Simple hyperplasia with atypia
Simple hyperplasia without atypia
Complex hyperplasia with atypia
Complex hyperplasia without atypia
2c
single
Answer is option3, complex hyperplasia with atypia Endometrial hyperplasia with atypia is the least common type of hyperplasia, but is the type most likely to progress to type 1 endometrial carcinoma (1-3) which accounts for 97% of uterine cancers, whereas simple hyperplasia rarely progresses to carcinoma. >
Pathology
General pathology
1ae6bb17-5bc8-4c67-bac0-0a965653968e
The Millennium Development Goals (MUG) is to be achieved by the year -
2010
2015
2020
2030
1b
single
Ans. is 'b' i.e., 2015
Social & Preventive Medicine
null
6fdacf93-d4c2-4666-8e45-a524e8ac38db
Systemic causes of epistaxis are all except:
Hypeension
Anticoagulant treatment
Hereditary telangietasia
Hemophilia
3d
multi
Hemophilia is secondary cause of epistaxis in children. Ref.Scott Brown 7/e,vol 2,p 1605
ENT
Nose and paranasal sinuses
709dc647-846a-453f-9d73-31d9522220d6
Which of the following situations will lead to increased viscosity of blood:
Fasting state
Hypoglycemia
Multiple myeloma
Amyloidogenesis
2c
single
C i.e. Multiple myeloma
Medicine
null
ddf0d9e7-c8d4-4500-89ce-b1ef7e0ff3e7
A person is being treated for Human Immunodeficiency Virus-1. He developed hyperiglyceridemia and hypercholesterolemia. Most likely drug implicated for these adverse effects is
Ritonavir
Raltegravir
Tenofovir
Eirenz
0a
single
Ritonavir is a protease inhibitor and can cause hyperiglyceridemia and hypercholesterolemia. All protease inhibitors are metabolized by liver and all can cause metabolic abnormalities including hypercholesterolemia, diabetes mellitus, hyperlipidemia, insulin resistance and altered fat istribution (lipodystrophy). Ataza...
Pharmacology
Anti-HIV Drugs
c4caf996-8488-4544-8b77-cb583fb76e2e
Ropinirole is most useful for the treatment of:
Parkinson's disease
Wilson's disease
Hoffmann syndrome
Carpal tunnel syndrome
0a
single
Ans. (A) Parkinson's disease(Ref: KDT 8/e p457)Ropinirole is a non-ergot dopamine agonist useful for Parkinsonism. It is also used these days for restless leg syndrome.
Pharmacology
C.N.S
e8ab8c32-a9b6-4c3d-8ef1-012831dea02d
Which of the following helminths primarily produces gastrointestinal symptoms, without lung involvement, during the course of its infection?
Dirofilaria immitis
Strongyloides stercoralis
Trichuris trichiura
Ascaris lumbricoides
2c
single
Trichuris humans acquire the infection by eating foods contaminated with infective eggs. Once eggs are swallowed, the larvae hatch in the small intestine, where they mature and migrate to the colon. Trichuris infections with a low worm burden are usually asymptomatic, but infections of moderate to heavy worm loads pres...
Microbiology
All India exam
5b59a952-dfae-494b-a52a-2a60aa937de3
In solitary thyroid nodule true is/are :
THR-Ab
Lined by columnar epithelium
Diffuse hyperplasia of thyroid
Common in female
3d
multi
Ans. is 'd' i.e. Common in female A solitary thyroid nodule is a palpably discrete swelling within an otherwise apparently normal thyroid gland. Ceain imp. points about solitary thyroid nodules : STN are more common in women than in men The incidence of STN increases with age Solitary nodules, in general, are more like...
Surgery
null
1081fe83-1f89-42f1-879c-592702c57f9c
Indications of celiotomy in blunt trauma:
Grade I spleen damage
Grade II liver damage
Peritoneal air on imaging
All
2c
multi
Ans is C (Peritoneal air on imaging) Most spleen and liver injuries are managed non-operatively, if the patient is hemodynamically stable.
Surgery
null
cb5d35ed-508b-48e1-934d-580e070e7330
Two most impoant tests to be done in a comatose patient with blood glucose of 750 mg/dl will be -
Sr. creatinine
Sr. sodium
CSF examination
Blood pH
0a
single
Comatose patients with blood glucose level of 750 mg/dl suggests the possibility of hyperglycemic hyperosmolar state . Lab abnormality in this is marked hyperglycemia, hyperosmolarity, prerenal azotemia. Comatose patients with hyperglycemia is also seen in diabetic ketoacidosis. Thus blood ph ( to detect acidosis) and ...
Medicine
Endocrinology
79fa4140-1f33-4167-a30b-7d6b1496c217
A different sequence of amino acids having a similar structure of proteins is an example of
Divergence
Convergence
Opportunistic
Incidental
1b
single
Divergence and convergence are two evolutionary processes by which organisms become adapted to their environments. Convergence has been defined as the acquisition of morphologically similar traits between distinctly unrelated organisms. Convergence occurs at every level of biological organization. Functional Convergen...
Biochemistry
null
f36fe1fd-bdae-4329-9ff2-8b96d7c92949
Shelf life of Platelets is
< 5 days
< 3 weeks
< 5 weeks
< 2 years
0a
single
Shelf life of Platelets is < 5 days Cryoprecipitate is 2 years.
Medicine
null
2e67b5ca-2efe-432a-adec-6a21881c3bf3
Phenomenon called anticipation is seen in?
Mitochondrial inheritance
x - linked dominant disorders
Trinucleotide repeat expansion
Genomic imprinting
2c
multi
Instablity of triplet repeats can lead to gradual expansion from generation to generation,a phenomenon called anticipation,Genetic anticipation is characterized  by the reduction in the age of disease onset  by successive genarations.
Pathology
null
41fffdb3-b7e1-4799-8baf-930e25362745
Lung is characteristically involved in -
Churg-Strauss syndrome
HSP
PAN
ITP
0a
multi
Ans. is 'a' i.e., Churg-Strauss syndromeChurg- strauss syndrome o Also known as allergic granulomatosis and angitis.o It is a medium and small size vasculitis, invoves mainly the blood vessels of lungs, GIT, peripheral nerves, hea, skin, kidney.o As it is allergic, vasculitis it is associated with eosinophilia and asth...
Pathology
null
f73c5da1-ab29-4ca8-b670-268e8a9f2645
Which of the following drugs is used for narcoanalysis -
Atropine
Phenobarbitone
Scopolamine
Pethidine
2c
single
Scopolamine is used as truth serum. Drugs commonly used in narcoanalysis are 1. Thiopentone sodium (Sodium pentothal) 2. Scopolamine hydrobromide 3. Sodium secnol 4. Benzodiazepines REF;THE SYNOPSIS OF FORENSIC MEDICINE:KS NARAYANA REDDY;28th EDITION
Forensic Medicine
Poisoning
ebd2773c-d81f-488e-b1d6-b8d4e5ba2ad3
Commonest organism giving rise to urinary tract infection -
E. coli
Proteus
Staphylococcus
Streptococcus
0a
single
• Most UTIs are caused by a single bacterial species. • At least 80% of the uncomplicated cystitis and pyelonephritis are due to E. coli, with most of pathogenic strains belonging to the O serogroups. • Other less common uropathogens include Klebsiella, Proteus, and Enterobacter spp. and enterococci. • In hospital acqu...
Surgery
null
38a3e1b8-705c-47cb-961b-8908e9d88503
Carbamide solution used for bleaching degrades into
0.3% sodium perborate
30% hydrogen peroxide
3% hydrogen peroxide
30% sodium perborate
2c
single
null
Dental
null
13002cb8-942b-42bd-98b0-a85886c94c07
Mechanism of action of sildenafil is
Inhibits PDE 2
Inhibits PDE 4
Inhibits PDE 5
Inhibits PDE 3
2c
single
Ans. is 'c' i.e., Inhibits PDE 5 * Sildenafil (Viagra) acts to increase cGMP by inhibiting its breakdown by phosphodiesterase isoform 5 (PDE-5).
Pharmacology
Miscellaneous (Pharmacology)
f4b84482-f856-4ea3-b60f-8a121ff1a49d
Intercourse can be cumbersome, annoying & also 'Noisy' with the use of which of the following :
Male condom
Female condom
IUCD
Vaginal ring
1b
single
Disadvantages of female condoms: 1. Intercourse is noisy, and slippage occurs in about one in 5-10 uses; however, female condom rarely breaks. 2. Occasionally the penis is introduced, by mistake, outside the female condom, which may lead to pregnancy and STDs including HIV. 3. It is an expensive method.
Gynaecology & Obstetrics
Contraceptives
3ab18fa0-d119-46e1-a38d-7888f854b14c
Which virus given below is not a teratogenic virus ?
Rubella
Cytomegalovirus
Herpes simplex
Measles
3d
single
Ans. is 'd' i.e., Measles Many viruses can be transmitted to the fetus and cause infection and tissure damage. Five viruses are known to be teratogenic in humans: cytomegalovirus, rubella, herpes simplex, Venezuelan equine encephalitis, and varicella viruses.
Microbiology
null
dc0cd454-82f0-4b0d-82a2-70190cc41ea1
Vector for T.cruzi is -
Reduvid bug
Tsetse fly
Sand fly
Hard tick
0a
single
T.cruzi passes its life cycle I two host Definitive host- humans Intermediate host-triatomine bugs Humans become infectious when reduviid bug bites and the infected faecal matter is discharged near bite wound (refer pgno:49 baveja 3 rd edition)
Microbiology
parasitology
d08aa898-c9f8-421e-96cc-cd3272a9b5b9
Which of the following is most commonly involved in Hypersensitivity vasculitis:
Capillaries
Aerioles
Post-capillary venules
Medium sized aeries
2c
single
Answer is C (Post-capillary venules): Post-capillary venules are most commonly involved in Hypersensitivity vasculitis Hypersensitivity vasculitis Hypersensitivity vasculitis refers to small vessel vasculitis that is restricted to the skin and not associated with any other form of primary or secondary vasculitis. Impli...
Medicine
null
8865278a-5360-4e66-b4dc-4d6013826241
Hallmarks of the hemophilia is
Epistaxis
Hemarthrosis
Abdominal pain
Anaemia
1b
multi
(Hemarthroses): Ref: 326-G, 1657-Nelson 17th (321-Ghai 7th)Hemophilia - X-1 inked recessive, The females carries the hemophilia trait but only male offspring suffers from the disease.Clinical features - Bleeding following tooth extraction, severe trauma or following surgery muscle hematoma, and bleeding in joints.* Pro...
Pediatrics
Blood
e0b946d9-d756-4716-8c87-c558792dd281
For central venous pressure monitoring all are true except
Internal jugular vein is preferred site
Indicated to administer hyperosmolar drugs
Pulmonary capillary wedge pressure normally is 10-20 mmHg
Swan- ganz catheter entering pulmonary artery shows as dicrotic notch.
2c
multi
Pulmonary capillary wedge pressure in 4-12 mmHg normally.
Anaesthesia
null
30f2f606-5278-45a2-9cf9-686ce1585e72
Cranial end of Wolffian duct forms:
Epoophoron
Paraepoophoron
Gartner cyst
Bartholin cyst
0a
single
Ans: A (Epoophoron) Ref: Grays Anatomy 40th EdExplanation:Embryology of Reproductive SystemGonadMALES (Testis)FEMALES (Ovary)Gubernacular cord Mesonephros (Wolffian body)Gubernaculum testisOvarian and round ligamentsAppendix of epididymis (?)Appendices vesiculosae (?)Efferent ductulesEooophoronLobules of epididymis Par...
Unknown
null
a41e53bd-4ce6-4877-85ef-5ab8c27af288
A 60-year old male presents with progressive difficulty in swallowing, vomiting and occasional regurgitation for the past 3 months. Barium studied showed marked dilatation of the upper esophagus with narrowing of the lower segment. Manometry showed absent esophageal peristalsis. This patient needs to have -
Ballon dilatation
Endoscopic banding
Sclerotherapy
Proton pump inhibitor
0a
multi
The most common cause of narrowing of the esophagus, or stricture, is scarring of the esophagus from reflux of stomach acid occurring in patients with heaburn. Patients with a narrowed poion of the esophagus often have trouble swallowing; food feels like it is "stuck" in the chest region, causing discomfo or pain. Less...
Medicine
G.I.T
b585feb4-9615-481a-bef2-fce2f9d5ea98
Regarding ranula, all are true except -
Retention cyst
Arises from submandibular gland
Translucent
Plunging may be a feature
1b
multi
A ranula is a mucous retention cyst which arises from sublingual salivary gland and presents as fluctuant swelling with a bluish translucent colour. Types of Ranula Ranula may be of two types : - 1)Simple : - Situated in the floor of mouth without any cervical prolongation. 2)Deep/plunging : - Ranula with a cervical...
ENT
null
46f20a2a-755e-4562-bda4-cd3fd0c6731c
Thinnest labial plate is found in the region of:
Upper central incisors
Lower central incisors
Upper canines
Lower canines
1b
single
null
Dental
null
86799b51-64da-4c55-a02f-ab32d1504ec0
If thiopentone is injected accidently into an aery the first symptom is
Analgesia
Paralysis
Skin ulceration
Pain
3d
single
D i.e. Pain
Anaesthesia
null
68c63050-83c0-4669-8c29-9637d4061726
40 years old male patient came with complaint of dry cough and dyspnoea. On lung function tests, restrictive pattern of decreases lung function is seen. Chest x-ray showed few reticular opacities in bilateral lung. HRCT of lung was performed which shows GGO in bilateral lung fields sparing sub-pleural region. Most prob...
UIP
NSIP
Hypersensitivity pneumonitis
Respiratory bronchiolitis
1b
single
Interstitial Lung Disease UIP (Usual interstitial pneumonia) NSIP (Non - specific interstitial pneumonia) Reticular opacities Traction bronchiectasis Subpleural honeycombing Subpleural sparing
Radiology
Radiology Q Bank
59faef49-7dda-434f-89be-2d9a2e4138cd
Malignant gastric ulcers are characterized by all except
ulcer extends beyond the gastric wall.
Mucosal rugae stop far of ulcers
Eccentric crater
Margins are raised
0a
multi
In malignant ulcers mucosal rugae stop far of the ulcers whereas in benign ulcers mucosal rugae projects outwards front the margins of the ulcer
Pathology
null
6105a32b-f642-4b65-bf6c-4847310d065b
The measure of strength of association between risk factor and outcome is:
Odds ratio
Attributable risk
Relative risk
Poisson's ratio
0a
single
It is a measure of the strength of association between risk factor and outcome. The derivation of the Odds ratio is based on three assumptions:  a) The disease being investigated must be relatively rare. In fact, the majority of chronic diseases have a low incidence in the general population. b) The cases must be rep...
Dental
null
378ae4f9-5261-4def-9ae3-afe4caa39adf
The following affect enzyme activity except
Methylation
Acetylation
Induction
Phosphorylation
2c
multi
Regulation of Enzymes Can be classified as: Regulation of Enzyme Quality (Intrinsic Catalytic Efficiency) • Allosteric Regulation • Covalent modification. Covalent modification • Phosphorylation/dephosphorylation • Methylation • Adenylation • ADP ribosylation • Acetylation. Regulation of enzyme quantity Control of En...
Biochemistry
null
327a02c7-48b3-476d-99a2-628840d5d751
Aggrecan is:
A receptor over platelets
A molecule present in osteoid tissue
Granules in leukocytes
Impoant component of cailage
3d
single
Aggrecan is a proteoglycan, also known as cailage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1. It is encoded by the ACAN gene. Aggrecan is an integral pa of the extracellular matrix (ECM) in cailagenous tissue and it withstands compression in cailage.
Physiology
Concepts in physiology
3a17848e-5035-41d7-b828-bd717f08c03d
Feature of diabetes mellitus in pregnancy:a) Postdatismb) Hydramniosc) Neonatal hyperglycemiad) ↑congenital defecte) PPH
bde
ade
ace
bce
0a
single
As explained in the previous question maternal hyperglycaemia leads to fetal hyperglycaemia, which in turn causes polyuria and thus causes polyhydramnios. Polyhydramnios leads to preterm delivery and not post datism. Excessive uterine enlargement because of polyhydramnios and macrosomia causes increased incidence of ...
Gynaecology & Obstetrics
null
dcc29e89-1737-4b7d-b358-2ebcbec9307f
Treatment of Mycobacteria avium complex include all except :
Ciprofloxacin
Clarithromycin
Rifabutin
Pyrazinamide
3d
multi
null
Pharmacology
null
1ed4e42b-0cd6-4aa0-8429-59a2fe0c5edf
Specific antibody associated with primary biliary cirrhosis is:
Anti-myosin
Anti-nuclear
Anti-mitochondrial
Anti-endomysial
2c
single
Ans. C: Anti-mitochondrial Primary biliary cirrhosis is strongly associated with the presence of anti-mitochondrial antibodies (AMA), which are diagnostic PBC: Associated with CREST syndrome, sicca syndrome, auto-immune thyroiditis, type I DM and IgA deficiency IgG AMA is detected in more than 90% of patients with PBC ...
Medicine
null
69c8235c-e810-46f2-8a9f-23d5430f8940
Long acting insulin is?
Insulin glargine
Insulin Lispro
Insulin aspart
Insulin glulisine
0a
single
ANSWER: (A) Insulin glargineREF: Pharmacology ReCap 2.0 for Bachelor of Dentistry Students by Dr. J. G. Buch page 304, Harrison s 18m ed chapter 344INSULINS:Highly purifiedmono-componentinsulinPorcine Actrapid- RegularShort actingPorcine Monotard- LenteIntermediate actingPorcine Insulatard- NPH Porcine Mixtard30% regul...
Pharmacology
Endocrinology
4f2dd91a-9b19-4160-b450-7079c4f378cd
Which of the following is not an alkylating agent?
Cyclophosphamide
Busulfan
5-Fluorouracil
Melphalan
2c
single
5- Fluorouracil' Repeat from AI1MS 09
Pharmacology
null