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And, in any case, the state board syllabus is useless and serves only the cause of paper re-cyclers. |
Hence, please watch-out before you falter again as during the current times, the people don’t forgive politicians that are irresponsible. |
A concerned citizen of India. |
One thought on “Jayalalithaa's second fall in 100 days |
1. I am also disappointed that the assembly passed such a resolution. I generally appreciate her administrative capabilities and strong no nonsense views. Why she succumbed to this populist demand, is not clear. However I beg to differ from you on the Uniform System of Education. |
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Genus: Lymphocystivirus |
Genus: Lymphocystivirus |
Distinguishing features |
In contrast to the systemic infections seen with ranaviruses and megalocytiviruses, lymphocystivirus infections result in wart-like growths mainly on the skin of infected fish. These growths are composed of numerous, greatly enlarged, cells. Infected cells are commonly 100 μm in diameter and sometimes reach 1 mm. Lymph... |
Particle size varies from 198 to 227 nm for lymphocystis disease virus 1 (LCDV1) and 200 nm for lymphocystis disease virus 2 (LCDV2). The icosahedral capsid may show a fringe of fibril-like external protrusions about 2.5 nm in length. The presence of capsid fibers distinguishes lymphocystiviruses from members of the ot... |
Physicochemical and physical properties |
Virions are heat labile. Infectivity is sensitive to treatment with ether or glycerol. |
Nucleic acid |
Within the genus, genomes vary from 98 kbp (LCDV2) to 209 kbp (lymphocystis disease virus – Sparus auratus, LCDV-Sa), the last is the largest known genome among vertebrate iridoviruses. A contour length measurement of 146 kbp for LCDV1 suggests a terminal redundancy of approximately 50%. Like other vertebrate iridoviri... |
Little is known about the protein composition of lymphocystiviruses. The reported genomes are sufficient to encode between 108–183 proteins. BLAST analysis of predicted ORFs suggests that many putative gene products may be unique to the genus. |
Genome organization and replication |
The LCDV1 genome (103 kbp) contains 108 largely non-overlapping putative ORFs, 38 of which show significant homology to proteins of known function. These 38 ORFs represent 43% of the coding capacity of the genome. The presence of a DNA methyltransferase and a methyl-sensitive restriction endonuclease with specificity f... |
The LCDV-C genome contains 178 non-overlapping ORFs, 103 of which are homologs to the corresponding ORFs of LCDV1 and 75 potential genes that were not found in LCDV1 or other iridovirids. Among these 75 genes, there are eight genes that contain conserved domains of cellular genes and 67 novel genes that do not show any... |
The genome of LCDV-Sa contains 183 putative ORFs. BLASTp analysis found that 145 ORFs displayed significant similarity to other genes in the database. Of these 145, 129 best match those in LCDV-C, 10 best match LCDV1, two match ORFs within the scale drop disease virus (unclassified isolate, Megalocytivirus) genome and ... |
A lack of cell lines suitable for in vitro replication has hindered analysis of LCDV biogenesis. Because few studies have been conducted, it has been assumed that LCDV replication is generally similar to frog virus 3. Electron microscopy indicates that as with other iridovirids, virus assembly occurs in and around viro... |
The major capsid protein (MCP) is antigenic and protective antibodies are produced following exposure to this protein. There are other immunogenic viral proteins including one of 60 kDa for which a polyclonal antiserum provides a diagnostic reagent (Cano et al., 2006). In addition, monoclonal antibodies have been raise... |
Lymphocystis disease was the first clinical illness linked with an iridovirus. However, although clinical manifestations of infection (i.e., wart-like or tumor-like growths on the skin of infected fish) were first noted near the end of the 19th century, the specific etiological agent was not identified until nearly 100... |
LCDV1 and LCDV-C infect flounder and plaice, LCDV2 infects dab, and LCDV-Sa infects gilthead seabream. Isolates have also been obtained from other infected fish species, but their taxonomic position is unclear . Infection targets fibroblasts and results in wart-like lesions comprising grossly hypertrophied cells occurr... |
Species demarcation criteria |
Definitive criteria have not yet been established to delineate viral species. In the future, species may be distinguished from one another by DNA sequence analysis and PCR. PCR primers targeted to regions within the MCP and ORF167L can be used to identify isolates. |
Phylogenetic analysis based on MCP, DNA polymerase and myristylated membrane protein genes indicates that lymphocystovirus isolates display considerable sequence diversity. Overall the genome of LCDV-Sa shares 55% identity to LCDV-C and 39% with LCDV1; LCDV1 and LCDV-C shared 42% identity to each other. Dot plot analys... |
Member species |
Lymphocystis disease virus 1lymphocystis disease virus 1L63545NC_001824Complete genomeLCDV1 |
Derivation of names |
Isolates are named after the associated disease and the chronological order in which the sample was isolated (e.g., LCDV1), the geographic location of the isolate (e.g., LCDV-C, China), or the host from which it was isolated (e.g., LCDV-Sa, Sparus auratus (gilthead seabream)). |
Related, unclassified viruses |
Virus name |
Accession numbera |
Virus abbreviation |
Genome (bp) |
lymphocystis disease virus – China |
lymphocystis disease virus – Sparus auratus |
lymphocystitis disease virus-paradise fish |
lymphocystis disease virus – painted glassfish |
lymphocystis disease virus – pearl gourami |
lymphocystis disease virus - rockfish |
lymphocystis disease virus 2 |
Virus names and abbreviations are not official ICTV designations. |
ND: not determined. |
a Full genome sequences have been determined for LCDV-C and LCDV-Sa. For the other isolates, the major capsid protein gene sequence (LCDV-PF, -PaGl, -PeGr, and -RF) or a TNFαR-like protein (LCDV2) gene sequence have been determined. |
VR memory concentration game for Google Cardboard |
VR MemoMemo – A virtual reality memory game |
for Google Cardboard, iOS & Android |
What is this project about? |
For this project, I designed a mobile VR game app with a basic multi-player feature. It is a memory game in 3D, also known as concentration game. It can be played with any number of players or as solitaire. Virtual 3D cubes are clickable and reveal a pattern on click. The user has to find a pair of cubes of matching pa... |
As audience the app targets users of all ages who are interested in Virtual Reality and want to train their memory and concentration just for fun. |
I also wanted to show VR basics to new users, to guide them through the very first steps when trying a Google Cardboard app for the first time, and to keep them interested in VR. |
For performance reasons, I wanted to use just low-poly models, but in well designed virtual premises. Credits of the paintings, artwork and cube patterns: Bernd Terwey |
Statement of Purpose |
The famous memory game as VR experience |
„VR MemoMemo“ for Google Cardboard is an experience for new VR users, inspired by the classic Memory boardgame. |
Persona, characteristics of our typical user |
Dominique is aged 10-80, interested in fine arts, and new state-of-the-art technologies, is familiar to mobile devices, but not yet very familiar to VR. Dominique is curious and eager to learn new things. Dominique likes playing the piano as well as games on mobile devices, from time to time. |
Concept in Powerpoint: |
1. Scale |
Correctly use scale to make the user feel about human height DONE |
2. Animation |
animation, either via scripting or a tool like Mecanim, to bring the scene to life. DONE |
3. Lighting |
Using a mix of baked and real-time lighting to add realistic shading to each scene and optimize the performance DONE |
4. Locomotion |
Using waypoints DONE |
6. Video Player |
7. Physics |
Optional, simulate flying particles, if time left. DONE (object pooling) |
1. Gamification |
The app is a memory game in 3D. The user shall find the right pair of matching cube patterns to receive a point. DONE |
2. Diegetic UI |
Instead of adding a lot of text to the scenes, interface elements are naturally represented, so users intuitively find things for themselves. Unclicked Memory Art Cubes initially have a glowing texture. |
EDIT: I tried this, but considering the user test results, 60% of my users did not know VR and how to use the reticle, or how to play the memory game, I decided to include an introductory scene to explain the game rules and the VR reticle. |
3. Alternative Storyline |
Users can choose between a solitaire- and a multi-player version. DONE |
4. Custom 3D modelling or Photogrammetry |
Optional. Creating some sculptures or interior design elements to fill the museum. They help the users to orientate themselves in the 3D rooms. DONE (The photogrammetry model looked ugly.) |
1. User testing |
Complete at least 2 User Tests and show the notes in your video about what you learned from each test. DONE |
2. Multi-player |
I used the network solution by Photon, photonengine.com. DONE |
3. App Downloads |
Get 100 app downloads within 1 week. DONE |
User test no 1 |
of the very first prototype |
At this point, the scene showed a white medium large hall. The rooms were arranged like a maze. |
The user could „walk“ and teleport to the red-white buoys by clicking on them. |
The art cubes were also clickable. The lighting had not been set yet. |
Instructions like a How-To section were missing. |
User 1 & User 2 |
with 2 app testers experienced with Google Cardboard VR. |
Q: Do you feel well represented in this VR space? |
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