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This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 12.0-999.0, Leishmaniasis, Cutaneous Leishmania Braziliensis Complex Leishmaniasis, American Leishmaniasis; American, Cutaneous Gender: Male or female Age: >12 yrs of age Presentation: 1-to-2 ulcerative lesions, each < 30 mm in largest diameter and with a total lesion area <900 mm2 Parasitology:... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Hepatitis B， Chronic Patients with chronic HBV infection (defined as HBsAg positive for at least 6 months) Co-infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV) and/or hepatitis D virus (HDV) History of liver transplantation History of hepatocellular carcinoma... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-65.0, B-cell Non-Hodgkin's Lymphoma Diagnosed as B-cell Non-Hodgkin's Lymphoma (NHL) according to "2008 WHO classification of tumors of haematopoietic and lymphoid tissues", including Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma, transform... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-76.0, Metastatic Colorectal Cancer Performance status ECOG-WHO 0 or 1 Histologically proved metastatic colorectal adenocarcinoma, with non-resectable metastases Adequate hematological, hepatic, and renal functions Signed written informed consent Previous treatment (chemotherapy, targeted t... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Hematopoietic/Lymphoid Cancer Richter's Transformation Patients with previously treated CLL and biopsy-proven Richter's transformation with DLBCL histology according to IWCLL (Richter Transformation RT) and CD19 positive by flow cytometry OR immunohistochemistry. 2. Eastern Co-operat... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Non Hodgkin Lymphoma Follicular Lymphoma Indolent Lymphoma B-cell Lymphoma Transformed Lymphoma Marginal Zone Lymphoma Waldenstrom Macroglobulinemia Small Lymphocytic Lymphoma Lymphoplasmacytic Lymphoma Histologically documented (by HPI or pathology report) iNHL as defined by follicu... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Diffuse Large B Cell Lymphoma Key 1. Histologically confirmed non-germinal center diffuse large B cell lymphoma (DLBCL), by immunohistochemistry using the Hans algorithm, 1. CD10 and BCL6-, 2. CD10-, BCL6+, but MUM1+ 2. Men and women ≥ 18 years of age. 3. Eastern Cooperative Oncology... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-80.0, Richter Syndrome confirmed Richter's transformation in treatment naïve and previously treated chronic lymphocytic leukemia/small lymphocytic lymphoma patients may have had prior exposure to ibrutinib and other B-cell signaling receptor agents Adequate hematologic function Adequate liv... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 21.0-75.0, Hepatic Encephalopathy Cirrhosis, Liver 75 years of age Cirrhosis diagnosed by either of the following in a patient with chronic liver disease (a) Liver Biopsy (b) Radiologic evidence of varices, cirrhosis or portal hypertension (c) Laboratory evidence of platelet count <100,000 or AS... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Chronic Lymphocytic Leukemia Richter's Transformation Have documented CLL according to iwCLL 2. a) CLL requiring transplant according to the consensus statement 2014 Non-response or early relapse within 24 months after purine analogue combination therapy or treatment of similar effica... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Hepatitis C Age > 18 years, male or female 2. Willing and able to comply with program assessment, including routine tests, attendance for follow up and compliance with medicine taking. 3. Able to provide written agreement (or witnessed in the case of patients who cannot read and writ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lymphoma, B-Cell Small Lymphocytic Lymphoma Chronic Lymphocytic Leukemia Waldenstrom Macroglobulinemia Mantle Cell Lymphoma Diffuse Large B Cell Lymphoma Richter's Transformation Follicular Lymphoma Marginal Zone Lymphoma Each prospective subject must meet ALL of the following in ord... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Arthroplasty Complications Inflammatory Response end stage knee OA necessitating TKR surgeries autoimmune diseases, malignancies, previous knee surgery or post-traumatic arthritis | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Cervical Cancer Age : 18-70 years old; 2. Histology or cytology confirmed cervical squamous cell carcinomas; 3. 2009 FIGO stage includesⅠB2, ⅡA2, ⅡB-ⅣA; 4. Performance status(PS): 0-1; 5. Peripheral blood meet the following conditions: neutrophil count > 2.0 * 109/L, white blood cell ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Del(17P) Patients diagnosed as CLL years or older Able and willing to provide the written informed consent Younger than 18 years | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 20.0-120.0, Part1: Advanced B-cell Malignancies Part2: r/rCLL and r/rMCL Part3: Untreated CLL Key Provision of signed and dated, written informed consent prior to any study specific procedures, sampling and analyses Japanese subjects at least 20 years of age at the time of study entry Presence o... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 13.0-68.0, To Compare the Effects of Mycophenolate Mofetil With Cyclophosphamide in Neplaese Lupus Nephritis Patients Newly diagnosed LN with ISN/RPS histopathology classes III to V Patients with biopsy had proven ISN / RPS classes I, II and VI LN Patients with previous history of treatment and... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Kidney Failure Dialysis Related Complication hemodialytic treatment from at least 6 months (3 times for week), blood flow rate during dialysis session (Qb) ≥250 ml/min using arterovenous fistula (AVF) or permanent central venous catheter (CVC), blood creatinine clearance <5 m... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lymphoma Non-Hodgkin Lymphoma Diffuse Large B-Cell Lymphoma Burkitt Lymphoma Patients must have histologically or cytologically confirmed B-cell lymphoma confirmed by the Laboratory of Pathology, NCI, as follows: Phase1b Aggressive B-cell lymphoma: includes DLBCL and subtypes, transf... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia in Relapse Chronic Lymphocytic Leukemia in Remission Documented CLL or SLL requiring treatment according to IWCLL after either being refractory to first line therapy or relapse after initial therapy Age at least 18 years Adequate bone marrow function defi... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Benign Paroxysmal Positional Vertigo patients who have had symptoms of vertigo for at least 1 week duration patients with a documented positive Dix-Hallpike test on referral patients with intact cognitive function and had the ability to communicate and understand instructions to perf... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Intrathoracic Lymphadenopathy Indication to sampling of intrathoracic lymphadenopathy based on computed tomography (CT) and/or positron emission tomography (PET)/CT findings Signed informed consent High risk conditions for the performance of bronchoscopy and endobronchial ultrasound... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, B Acute Lymphoblastic Leukemia CD19 Positive Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation Diffuse Large B-Cell Lymphoma, Not Otherwise Specified Epstein-Barr Virus Positive Diffuse Large B-Cell Lymphoma of the Elderly Minimal Residual Disease Philadelphia Chromo... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 40.0-999.0, Health Status Unknown Elevated PSA Written informed consent and Health Insurance Portability and Accountability Act (HIPAA) authorization for release of personal health information Note: HIPAA authorization may be included in the informed consent or obtained separately Eastern Cooper... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Schizophrenia Spectrum and Other Psychotic Disorders he/she currently uses CLZ or he/she has used CLZ in the past/will use CLZ he/she has received a diagnosis of schizophrenia, schizophreniform disorder, schizoaffective disorder or psychotic disorder NOS his/her age must be ≥18 years... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 14.0-999.0, Non-Hodgkin Lymphoma Lymphoma Diffuse Large B-Cell Lymphoma Gray Zone Lymphoma Primary Central Nervious System Lymphoma Patients must have a diagnosis of B-cell lymphoma confirmed by Laboratory of Pathology, NCI, that is relapsed from or refractory to prior therapy as follows Cohort ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Velopharyngeal Insufficiency Patients must have border line velopharyngeal abnormality which was diagnosed clinically. Ability to understand and the willingness to sign a written informed consent(if he was a child so his parents or his guardian should has tis ability) Mental Retardat... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lymphoma Adult T-Cell Leukemia/Lymphoma Lymphatic Diseases Subjects must meet all of the following to participate in this study: 1. Informed consent and HIPAA authorization for release of personal health information obtained. 2. Age ≥ 18 years at the time of consent. 3. Eastern Coope... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Melanoma Age > 18 years 2. Primary melanoma > 1 mm in Breslow depth 3. Stage III or IV disease as determined either by sentinel node biopsy, biopsy of clinically enlarged lymph nodes, and/or imaging. If stage IV, must have tissue biopsy confirming presence of stage IV melanoma Pregn... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, CD20 Positive Mantle Cell Lymphoma FOR (STEP 0 Patients must have histologically confirmed mantle cell lymphoma, with documented cluster of differentiation (CD19) or CD20 expression and cyclin D1 (BCL1) by immunohistochemical stains and/or t(11;14) by cytogenetics or fluorescence in s... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Hypersplenism All patients with documented evidence of liver cirrhosis (of any etiology other than alcoholic cirrhosis) and portal hypertension, based on clinical examination, abdominal ultrasound examination, upper gastrointestinal endoscopy Male and female patients aged between 18-6... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 19.0-999.0, Cardiovascular Diseases Neuro-Degenerative Disease Cancer Pregnancy Men and women Older than 18 years Cardiovascular disease neurodegenerative disease Cancer Pregnancy Inability to understand and to want Refusal to sign the informed consent | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-64.0, Lymphoma, Large B-Cell, Diffuse Age 18 years Histologically confirmed CD20+ DLBCL based on revised WHO 2008 Lymphoma Classification. The following subgroups and variants can be included ALK-positive large B-cell lymphoma Intravascular large B-cell lymphoma T-cell rich B-cell lymphoma ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, B Cell Lymphoma B Cell Leukemia Myeloma Hepatocellular Carcinoma Pancreatic Carcinoma Adenocarcinoma of Esophagogastric Junction I. B-Cell Lymphoblastic Leukaemia/Lymphoma 1. Patients aged between 18 ~ 65 with B-cell lymphoblastic leukaemia/lymphoma. 2. CD19-positive B-cell lymphoblas... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Neoplasms, Malignant Breast Neoplasm Carcinoma, Basal Cell Carcinoma, Squamous Cell Melanoma Skin Neoplasm Head and Neck Neoplasms Subject must be capable of giving informed consent or has an acceptable surrogate capable of giving consent on behalf of the subject. 2. Subject has an e... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Renal Cell Carcinoma Histologically confirmed locally advanced or metastatic renal cell carcinoma, clear cell histology that can be considered for partial or complete nephrectomy cT1b-T2a Grade (G) 4, cT2b G3/4, c T3-cT4 any grade and any cT with cN1 or M1 disease Locally advanced di... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Gout CKD Stage 1-4 SUA Level (>8 mg/dL; 480 µmol/L) outpatient adults withgout and hyperurecemia (SUA level above 8 mg/dL (480 µmol/L) outpatient adults with CKD 1-4 stages and hyperurecemia (SUA level above 8 mg/dL (480 µmol/L) CKD 5 stage heart failure III-IV NYHA stroke peripheral... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-50.0, Persistent Post-Concussive Syndrome Man or woman aged 18-50 years. 2. Reports at least one PCS symptom that is mild in severity. 3. It has been two weeks since date of injury Has been previously diagnosed with a psychological/neurological disorder 2. Has been previously diagnosed wit... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma ≥ 18 years of age. 2. Diagnosis of CLL or SLL. 3. Received at least one prior anti-cancer therapy for CLL or SLL. 4. Previous exposure to BTKi and meet at least one of the below: 1. Progressive disease (PD) while receiving or wi... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Parkinson's Disease Diagnostic of Parkinson's disease by a neurologist Native French speaker Affiliated to social security Unmodified PD treatment for at least 2 weeks before the Over 18 years-old Accepting the study after reading the information note and signing the consentment form... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Cellular Diagnosis, Chronic Lymphocytic Leukemia All patients are newly diagnosed as CLL patients with associated malignancies | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Experimental Diagnosed as Diffuse Large B-Cell Lymphoma (DLBCL) and Follicular Lymphoma (FL) according to "2016 WHO classification of tumors of haematopoietic and lymphoid tissues"; 2. Patients must have received systemic treatment (including chemotherapy or Hematopoietic stem cell tr... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Acute Myeloid Leukemia Signed written informed consent according to ICH/EU/GCP and national local laws (if applicable) Patients aged ≥18 years affected by AML according to the FAB previously enrolled in Studies for AML treatment. AML patients with CNS involvement defined by the confi... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, B Cell Lymphocytic Leukemia B Cell Non-Hodgkin's Lymphoma New diagnosis of CD20 expressing B-NHL or CLL o Up to 1/3rd of enrolled patients may have CLL. Enrollment of patients with CLL will be halted if this criterion is reached Will receive an anti-CD20 monoclonal antibody treatment ... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Aortopathies Thoracic Aortic Aneurysm Aortic Valve Disease Thoracic Aortic Disease Thoracic Aortic Dissection Thoracic Aortic Rupture Ascending Aortic Disease Descending Aortic Disease Ascending Aortic Aneurysm Descending Aortic Aneurysm Marfan Syndrome Loeys-Dietz Syndrome Ehlers-Dan... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Autoimmune Cytopenia Associated With Chronic Lymphocytic Leukemia Patient with CLL Active autoimmune cytopenia Initiation of a treatment with ibrutinib or idelalisib for autoimmune cytopenia Other lymphoid hemopathy B Absence of documentation of the autoimmunity of cytopenia | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Clinical diagnosis of Chronic Lymphocytic Leukemia and has a toxic heavy metal load Toxic heavy metal load Pregnant Pacemaker implants Organ transplant recipients Psychotic episodes or epileptic seizures | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Have high risk CLL Have documented previously untreated CLL according to IWCLL Willing and able to provide written informed consent Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 Demonstrate adequate organ function Able to take ora... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 6.0-999.0, Gaucher Disease, Type III Gaucher disease patients diagnosed by low B-glucocerebrosidase deficiency and GBA mutation The participant is at least 6 years old at time of enrollment Under stable Cerezyme dosage for at least for 3 months Presence of lymphadenopathy Patient (and/or their ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Von Willebrand Disease Historically lowest VWF:Ag and/or VWF:RCo and/or VWF:CB ≤ 0.30 IU/mL and/or FVIII:C ≤ 0.40 IU/mL Treatment at a Hemophilia treatment center in the Netherlands All types of VWD All ages Other known bleeding disorders present | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Richter Syndrome Must have a confirmed diagnosis of chronic lymphocytic leukemia or small lymphocytic lymphoma requiring therapy, as per IW-CLL 2008 OR Biopsy proven transformation to diffuse large B cell lymphoma (DLBCL), consistent with Richter's Syndro... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Decompensated Cirrhosis chronic active HCV proved by the positivity of HCV RNA, elevated transaminases CTP score was >9, MELD score was <29 Decompensated cirrhosis with frequent hepatic encephalopathy (HE) or difficult to treat ascites exposure to previous antiviral therapy hepatocel... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-100.0, Diffuse Large B-cell Lymphoma(DLBCL) Mantle Cell Lymphoma (MCL) Follicular Lymphoma (FL) Subject has provided informed consent prior to initiation of any study-specific activities/procedures Age ≥ 18 at the time of informed consent Biopsy proven B-NHL including DLBCL, which also incl... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia CLL SLL Small Lymphocytic Lymphoma Be ≥18 years old 2. Have an established, pathologically confirmed diagnoses of CLL/ Small Lymphocytic Lymphoma (SLL) requiring therapy according to the 2018 IWCLL guidelines 3. Have received at least one prior therapy fo... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia (CLL) Subjects must have CLL or SLL In cohort 2, subjects must have TP53-aberrant disease defined as Del(17p) detected on karyotype and/or FISH; OR TP53 mutation Participants must have measurable disease (lymphocytosis > 5,000 / µl, or palpable or CT meas... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Cirrhosis Hepatic Encephalopathy Minimal Hepatic Encephalopathy Covert Hepatic Encephalopathy Age >18 years 2. Cirrhosis defined by any one of the following 1. Cirrhosis on liver biopsy or transient wave elastography 2. Nodular liver on imaging 3. Endoscopic or radiological evidence ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-99.0, Chronic Lymphocytic Leukemia Age ≥ 18 years of age Diagnosed with CLL To be considered CLL, the subject must have an absolute lymphocytosis in the blood of at least 5,000 lymphocytes per microliter, or bone marrow lymphocytosis greater than or equal to 30% of all nucleated cells Histo... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Richter Syndrome Diagnosis of a Diffuse Large B-Cell Lymphoma arising in the context of a Chronic Lymphocytic Leukemia (group 1) or diagnosis of a primitive Diffuse Large B-Cell Lymphoma (group 2), or diagnosis of a Diffuse Large B-Cell Lymphoma arising in a context of small cells lym... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, FLT3-ITD Mutation AML Patients with AML carrying Flt3 mutation; AND Patients with persistent leukemia despite at least two prior chemotherapy regimens Patients who are considered not fit for any form of leukemia treatment by the attending hematologists | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Comprehensive Education Patients over the age of 18 years undergoing routine gastroscopy 2. Informed consent Serious coronary heart disease and myocardial injury with serious heart failure 2. Stenosis of the esophagus or cardia obstruction 3. Acute pharyngitis and tonsillitis 4. Acut... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Haemophilia B Have a diagnosis of haemophilia B and been treated previously with factor IX Product Have started Alprolix treatment prior to enrolment visit, or at enrolment prescribed treatment with Alprolix, regardless of participation in the study Signed and dated informed consent p... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-65.0, HSV Herpes Labialis Age ≥18 and <65 2. Positive test for IgG against herpes simplex virus type 1 (HSV-1). 3. Groups A and B only: Clinical diagnosis of herpes labialis, which may be made at the screening visit based on the patient's self-reported history of symptoms. An active herpes ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.167-0.5, Severe Acute Malnutrition Group 1 (SAM) Infants between 2 and <6 months old with SAM as defined by weight-for-length < -3 Z and/ or bilateral pedal edema either sex caregiver willing to provide consent for enrolment of the infant caregiver willing to stay in the Nutritional Rehabilita... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Relapsed/Refractory Large B-cell Lymphoma Key Histologically proven large B-cell lymphoma including the following types Diffuse large B cell lymphoma (DLBCL) not otherwise specified (ABC/GCB) High grade B-cell lymphoma (HGBCL) with or without MYC and BCL2 and/or BCL6 rearrangement DL... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Mucopolysaccharidosis II Patients who will have completed clinical trial JR-141-BR21 Capable of providing written consent by himself, unless the patient is under the age of 18 years at the time of informed consent process, or it is not possible to obtain consent from the patient himse... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-70.0, Cirrhosis for EHM+ subjects Age between 18 and 70 (inclusive) Cirrhosis Minimal hepatic encephalopathy Expression of non opposition for EHM subjects Age between 18 and 70 (inclusive) Cirrhosis No hepatic encephalopathy (minimal or clinical) Paired with EHM+ subjects about age, gender,... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 8.0-65.0, CTLA4 Haplonisufficiency Chronic Cytopernia Individuals must meet all of the following to be eligible for study participation: 1. Age 8-65 years. 2. Documented CTLA4 mutation (requires documentation of confirmed mutation via Sanger sequencing at a laboratory approved by the Clinical La... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Relapsed or Refractory Chronic Lymphocytic Leukemia CLL that is relapsed or refractory to BTK inhibitors and is on a stable dose of venetoclax ECOG 0-2 Adequate bone marrow function Adequate renal function Adequate liver function INR <=1.2 in patients not receiving chronic anticoagul... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Lymph Node Disease clinically enlarged lymph nodes previous medical treatment or radiotherapy previous biopsy | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Arthroplasty, Replacement, Knee Preoperative Patient is undergoing a unilateral total knee arthroplasty procedure; and Patient is willing and able to give written informed consent for registry participation. Preoperative Patient has a known sensitivity or allergy to bovine and/or por... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 20.0-999.0, Biliary Tract Cancer Histologically confirmed BTC (cholangiocarcinoma or gall bladder (GB) cancer) , except ampulla of Vater cancer 2. In the event that the progression of the gemcitabine/cisplatin is experienced during or after discontinuation of the first line treatment for metasta... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-78.0, Nursing Care Patient Education Patients hospitalised in preparation to receive LDH surgery and who volunteered to participate Older than 18 years Could read and write in Turkish Scored between 1 and 3 in the classification systems of the American Society of Anesthesiologists were prep... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Chronic Hepatitis B HBsAg positive, HBeAg negative, antibody to HBeAg-positive; 2. Stable administration of anti-HBV neucleos(t)ides analogue mono therapy for at least more than one and a half year; 3. Demonstration of undetectable HBV DNA on three occasions, each at least 6 months ap... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 21.0-75.0, Cirrhosis Hepatic Encephalopathy Cirrhosis diagnosed by either of the following in a patient with chronic liver disease Liver Biopsy Radiologic evidence of varices, cirrhosis or portal hypertension Laboratory evidence of platelet count <100,000 or AST/ALT ratio>1 Endoscopic evidence o... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-13.0, Hemophilia Hemophilia A Hemophilia B Hemophilia A With Inhibitor Hemophilia B With Inhibitor Haemophilia B Without Inhibitor Haemophilia A Without Inhibitor Haemophilia Congenital hemophilia A; FVIII </=5% or congenital hemophilia B; FIX </=5% Birth date on or after January 1, 2010 Car... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-45.0, Hepatitis E Immunisation Subject must provide written informed consent. 2. Subject must be able to comprehend and willing to comply with all study visits and procedures (up to 13 months from enrollment). 3. Subject must be a man or a non-pregnant woman* aged 18-45 years (inclusive). *... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 12.0-999.0, Cutaneous Leishmaniasis, American and exlusion Gender: Male or female Age: >12 yrs of age Presentation: 1-to-2 ulcerative lesions, each < 30 mm in largest diameter and with a total lesion area <900 mm2 Parasitology: Parasitological confirmation of the lesion will be made by visualiza... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 3.0-65.0, Acute Lymphocytic Leukemia Subjects with acute lymphocytic leukemia who voluntarily signed informed consent and met the following 1. Patients with relapsed and refractory acute B lymphocytic leukemia with any of the following: 1. Recurrence after remission by chemotherapy or autologous... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lung Cancer Age > 18 years Indication for endoscopic sampling of suspected malignant lymphadenopathy or pulmonary lesion Written informed consent High risk conditions for the performance of bronchoscopy and/or EBUS-TBNA High risk condition for deep sedation (ASA 4) Pregnancy | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Kawasaki Disease Atypical Kawasaki Disease Affected children will be recruited if the treating clinician has made a diagnosis of possible Kawasaki disease (even if they do not fulfil the below for Kawasaki disease). The current standard diagnostic for KD (Circulation 2001 103 335-336 ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Liver Cirrhoses older than 18 years And signed informed consent And planned either a) liver transplantation as a recipient; or b) liver transplantation as a donor any absolute/relative contraindication of contrast-enhanced MRI | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Syncope Over 18 years Diagnosis of neurally mediated syncope with a tilting table test (Tilt test) that demonstrates a mixed (type 1) or cardioinhibitory response (Type 2A and 2B) Negative impact on work and social life Non-respondent to pharmacological therapy (Fludrocortisone 0.1mg... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Alcohol Use Disorder Alcohol Dependence Be at least 18 years of age. 2. Have a current (past 12 months) DSM-5 diagnosis of AUD (4 or more symptoms) assessed using the MINI neuropsychiatric interview version 7.0.2 (at least moderate severity, ICD-10-CM Code F10.20 alcohol dependence, ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Richter Syndrome Diffuse Large B Cell Lymphoma Follicular Lymphoma Indolent Non-hodgkin Lymphoma Loss of Chromosome 17p Lymphoplasmacytic Lymphoma Marginal Zone Lymphoma TP53 Gene Mutation Diagnosis of Richter syndrome (RS; transformed CLL), or indolent n... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Chronic Lymphocytic Leukemia Recurrent Diffuse Large B-Cell Lymphoma Refractory Diffuse Large B-Cell Lymphoma Richter Syndrome Small Lymphocytic Lymphoma Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma Transformed Follicular Lymphoma to Diffuse Large B-Cell ... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Richter Syndrome Entry for randomised trial component (standard of care and experimental arms): for the randomised trial component Suitable for anthracycline-containing chemo-immunotherapy Patients with CLL and newly diagnosed biopsy proven DLBCL-type RS ECOG performance status of 0,... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Hemophilia B Have a diagnosis of haemophilia B Have started Alprolix treatment prior to enrolment visit, or at enrolment prescribed treatment with Alprolix irrespective of participation in the study Signed and dated informed consent provided by the patient, or the patient's legally ac... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.083-18.0, Kawasaki Disease Appendicitis Patients with Kawasaki disease Acute abdomen requiring surgery Patients with chronic gastrointestinal disease Incomplete data on the charts | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Lymph Node Disease Imaging examination indicates enlarged intrathoracic lymph nodes need pathological diagnosis (any lymph node has a short diameter > 1 cm in CT or PET-CT SUV value > 2.5). 2. Accessible mediastinal and hilar lymphadenopathy to EBUS-TBNA. 3. Inform consent signed Co... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 20.0-80.0, Chronic Phase Chronic Myelogenous Leukemia Newly diagnosed CML patients 2. Receive TKI treatment (imatinib, nilotinib, dasatinib) selected among those admitted to the investigator's hospital. 3. Ageing group 20yr up to 80 yr CML patients who previously treated with TKI. 2. Age below ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 1.0-31.0, B Acute Lymphoblastic Leukemia B Lymphoblastic Lymphoma Down Syndrome All B-ALL patients must be enrolled on APEC14B1 and consented to Screening (Part A) prior to treatment and enrollment on AALL1731. APEC 14B1 is not a requirement for B-LLy patients. B-LLy patients may directly enroll... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Richter Syndrome Confirmed diagnosis of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma according to the revised iwCLL criteria19 with biopsy proven transformation to diffuse large B-cell lymphoma, consistent with RS according to the 2016 WHO classification Both pati... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-130.0, Phase I: Relapsed or Refractory B-cell Malignancies Phase II Cohort A: Relapsed or Refractory Mantle Cell Lymphoma Phase II Cohort B: Relapsed or Refractory Chronic Lymphocytic Leukemia Capable of giving signed informed consent which includes compliance with the requirements and rest... | 2 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-999.0, Melanoma Subjects must have histologically proven, malignant melanoma, that is advanced (stage IV) or is unresectable and therefore considered surgically incurable Subject's disease must be measurable by immune-related using clinical assessments or imaging Subjects must have at least... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 1.0-24.0, B Acute Lymphoblastic Leukemia B Lymphoblastic Lymphoma Central Nervous System Leukemia Mixed Phenotype Acute Leukemia Testicular Leukemia B-ALL and MPAL patients must be enrolled on APEC14B1 and consented to studies (Part A) prior to treatment and enrollment on AALL1732. Note that cen... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 0.0-999.0, Lung Cancer Metastatic Nodes, Lung Suspected and later on confirmed lung cancer Presence of at least one mediastinal lymph node measuring > 10 mm in short diameter on computerised Tomography Age <18 History any malignancy apart from non-melanomatous skin cancer Inability to give info... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Chronic Lymphocytic Leukemia Men or women ≥ 18 years and ≤ 75 of age. 2. Diagnosis of CLL/SLL that meets IWCLL diagnostic criteria. 3. Treatment-naive patients. Those patients received short-term substandard treatment are permitted if meet all the items listed below: 1. Untreated with... | 1 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-75.0, Hepatic Encephalopathy Acute-On-Chronic Liver Failure Age 18-75 years Patients with ACLF with presence of hepatic encephalopathy > grade 2 as per WHC Pregnant women or those who are suspected to be having acute fatty liver of pregnancy Malarial hepatopathy, enteric hepatitis, or isch... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 1.0-18.0, Health Care Associated Infection Hand Hygiene All intraoperative providers at Children's Hospital Colorado will be eligible to participate 2. Pediatric patients age 1-18 years old presenting to the main operating room at Children's Hospital Colorado who will require general anesthesia ... | 0 |
This is a 57-year-old gentleman with CLL and large cell transformation. He presented with his disease back in [**10/2119**] with an elevated white count and LDH. He was without any splenomegaly or any cytopenias at that time. He did have some bulky lymphadenopathy. He then completed four cycles of FCR therapy, which he... | eligible ages (years): 18.0-130.0, Chronic Lymphocytic Leukemia Men and women ≥18 years of age (or the legal age of consent in the jurisdiction in which the study is taking place) 2. Diagnosis of CLL that meets published diagnostic (Hallek et al. 2018): 1. Monoclonal B-cells (either kappa or lambda light chain restric... | 1 |
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