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Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Recurrent Mantle Cell Lymphoma Patients must have histologically or cytologically confirmed mantle cell lymphoma as defined by the World Health Organization; all patients must have either t(11;14) by karyotype or fluorescent in-situ hybridization (FISH) or positive immunohistochemist... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Metastatic Ureter Carcinoma Metastatic Urethral Carcinoma Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 Stage III Ureter Cancer AJCC v7 Stage III Urethral Cancer AJCC v7 Stage IV Bladder Urothelial Carcinoma AJCC v7 Stage IV Ureter Cancer AJCC v7 Stage IV Urethral Cancer AJCC... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Metastatic Pancreatic Adenocarcinoma Stage III Pancreatic Cancer AJCC v6 and v7 Stage IV Pancreatic Cancer AJCC v6 and v7 Unresectable Pancreatic Carcinoma PHASE I STUDY - ARM A (DOSE LEVEL 1) AND ARM B (DOSE LEVEL 2) Patients must have histologically or cytologically confirmed metas... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Advanced Solid Tumors Relapsed/Refractory Lymphoma Male or female participants 18 years of age or older. 2. Histologically or cytologically confirmed metastatic and/or advanced solid tumors or lymphomas for which standard curative or life-prolonging treatment does not exist or is no ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-45.0, Arrhythmias in Pregnancy Pregnant or postpartum women presenting to Groote Schuur Hospital with cardiovascular disease -Individuals with structural heart disease | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-65.0, Asthma Age 18-65 years 2. Diagnosis of severe asthma 3. Confirmed therapy adherence via serum Prednisolone and cortisol levels Mild and moderate asthma 2. Community acquired pneumonia 3. Acute porphyria 4. Pregnant and breast feeding women 5. Patients hypersensitive to ethylenediamin... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-42.0, Infertility Age of women <43 years 2. Normal uterine cavity on saline sonogram 3. Endometrial thickness >=8mm on the day of hCG Planned not to have fresh embryo transfer 2. Cycle cancelled prior to hCG administration 3. Natural cycle IVF 4. Presence of hydrosalpinges on scanning which... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Other Complication of Kidney Transplant Renal Transplant Rejection Male and female patients aged over 18 years with no immunological risk (PRA <25% and no DSA) who are receiving their first cadaveric or living kidney transplant. 2. Patients who, three months after the transplantation... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-60.0, Opioid Dependence Age 18-60. 2. Meets DSM-IV for current opiate dependence disorder of at least six months duration, supported by urine toxicology OR COWS score > or =6 OR Naloxone Challenge. 3. Voluntarily seeking treatment for opioid dependence. 4. In otherwise good health based on ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 5.0-999.0, Food Allergy Signed informed consent For single shot study: history of a hazelnut, walnut, celeriac allergy due to an unequivocal accidental exposure with typical acute allergic reaction within the preceding 2 years and positive allergen-specific skin prick test/specific Immunoglobuli... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Acromegaly Neuroendocrine Tumors Acromegaly Male or female patients ≥18 years of age Acromegaly currently treated with Sandostatin LAR NET Male or female patients ≥18 years of age Functional, well-differentiated (Grade 1 or Grade 2) NET with symptoms of carcinoid syndrome (number of ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Rosacea The subject is a male or female, who is at least 18 years of age or older at Screening visit. 2. The subject has a clinical diagnosis of mild to moderate erythemato-telangiectatic rosacea or mild to moderate papulo-pustular rosacea according to the National Rosacea Society gr... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-999.0, Macular Disease Patients who visit Department of Ophthalmology, Kagawa University Hospital with macular diseases, such as AMD, PCV, RAP, RVO, DME, ERM, MH, VMTS Patients who are agreed with the participation of this study None | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-80.0, Crohn Disease Subject has provided informed consent. 2. Male or female subjects, 18 to 80 years of age, inclusive. 3. Prior diagnosis of CD confirmed by endoscopy or imaging for > 3 months prior to enrollment with active disease, defined as a Crohn's Disease Activity Index (CDAI) scor... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Atrial Fibrillation ≥ 18 years of age Patients of African, European, and Hispanic descent History of typical or early-onset symptomatic (≥2 episodes/month) paroxysmal/persistent AF ECG that was recorded within 1 month of randomization showing AF Eligible for both Flecainide(Class I) ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-35.0, Sleep Pregnancy Stillbirth Infant, Low Birth Weight Infant, Small for Gestational Age Infant, Very Low Birth Weight Fetal Growth Retardation Fetal Hypoxia ≥18 years old low-risk singleton pregnancy entering the last trimester of pregnancy (in range 26-30 weeks of gestation) residing i... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Aggressive Systemic Mastocytosis (ASM) SM w Assoc Clonal Hema Non-mast Cell Lineage Disease (SM-AHNMD) Mast Cell Leukemia (MCL) Smoldering Systemic Mastocytosis (SSM) Indolent Systemic Mastocytosis (ISM) ISM Subgroup Fully Recruited Documented diagnosis of one of the following condit... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Aggressive Systemic Mastocytosis Mast Cell Leukemia Systemic Mastocytosis Diagnosis of systemic mastocytosis per 2008 World Health Organization (WHO) criteria. Those with advanced systemic mastocytosis (ASM); mast cell leukemia (MCL); or systemic mastocytosis-associated hematological... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Recurrent Lung Squamous Cell Carcinoma Stage IV Lung Squamous Cell Carcinoma AJCC v7 Patients must have histologically or cytologically confirmed stage IV or recurrent squamous cell lung cancer or KRAS mutant lung cancer that harbors any of the NFE2L2 mutations or KEAP1 mutations; an... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Systemic Mastocytosis Suspicion of systemic mastocytosis, for whom bone marrow sampling (bone marrow biopsy and/or bone marrow aspiration) is carried out as part of normal workup of the disease in the center of reference and centers of competence in mastocytosis Patient whose written... | 2 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Lymphoma, Mantle-Cell Histologically confirmed MCL Patients who have previously received treatment with ibrutinib (modified by amendment 1), including Completion of at least 1 cycle of treatment with ibrutinib and confirmed evidence of disease progression or refractoriness to treatme... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-65.0, Systemic Lupus Erythematosus Meet the American College of Rheumatology for the diagnosis of SLE，1997 Under standard treatment (≥ 2 months) at the time of Background treatment failed to control flares or to permit prednisone tapering With at least one of the following manifestations: t... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-75.0, Mastocytosis Systemic Mastocytosis Indolent Systemic Mastocytosis Diagnosis of indolent systemic mastocytosis (ISM) according to the WHO and the consensus proposal (2001) Experiencing at least one predefined qualifying symptom in at least two organ systems within 3 months of Screening... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-99.0, Drug-Related Side Effects and Adverse Reactions Adverse Drug Events Veterans age 18 years or older Having a VA primary care provider (PCP) at any VA facility in VISN-1 Planned discharge home (as opposed to another facility) Computer and internet access Anticipated to be discharged wit... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Lung Cancer Lung Metastases Histologically/cytologically proven primary thoracic or breast malignancy, lymphoma or lung metastases (which are not required to be biopsy-proven) treated with definitive intent at MSK Prior treatment with thoracic radiotherapy completed >4 weeks and ≤ 9 ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-75.0, Crohn's Disease A CDAI score greater than 150 at baseline was required for .(1) steroid-dependent: unable to reduce steroids below the equivalent of prednisone 10 mg/day (or budesonide below 3 mg/day) within 3 months of starting steroids, or who have a relapse within 3 months of stopp... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Tobacco Smoking Pregnancy the woman presents for her first prenatal visit before 14-week gestation she is a smoker years or older (legal age for consent and for consuming tobacco in Romania) married or in a stable relationship phone service in the home or mobile phone willing to have... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-65.0, Depression Subjects have signed a current version of the Informed Consent and HIPAA documents prior to initiation of study procedures Able to comprehend English Diagnosis of Diagnostic and Statistical Manual of Mental Disorders (DSM)-V major depression and currently off antidepressant... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 19.0-999.0, Chronic GVHD After HCT for Cancer or Immune Disease (Main) Newly diagnosed chronic GVHD as defined by the National Institutes of Health (NIH) Consensus with no more than 24 weeks of treatment with systemic steroids. AND 2. Chronic GVHD must be refractory or dependent to standard ther... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-37.0, Unexplained Infertility Infertility Primary or secondary infertility ≥12 months Diagnosis of unexplained infertility ≤36 months Anti-Mullerian hormone ≥0.4 ng/mL and/or follicle-stimulating hormone ≤13 IU/L in early follicular phase regular cycle of 25-35 days positive ovulation tests... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-55.0, Multiple Sclerosis, Relapsing-Remitting Diagnosis of RMS in accordance with the revised McDonald Received at least one previous immunization against TT or tetanus and diphtheria (DT/Td) or tetanus, diphtheria, and acellular pertussis (DTaP/Tdap) Expanded Disability Status Scale (EDSS)... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Pregnancy Pregnant women at ≥37 weeks gestation by reliable dating as determined by the American College of Obstetricians and Gynecologists (i.e. gestational age supported by one of the following: ultrasound prior to 20 weeks of gestation, fetal heart tones auscultated by Doppler for... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Malignant Digestive System Neoplasm Nausea and Vomiting Patients who have a diagnosis of GI malignancy and who are scheduled to receive their initial treatment with an oxaliplatin-containing regimen in combination with 5-fluorouracil; these combinations such as fluorouracil, oxalipla... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Aggressive Systemic Mastocytosis Systemic Mastocytosis-associated Hematologic Non-mast Cell Disease Mast Cell Leukemia Relapsed or Refractory Myeloid Malignancies For Part 1:Patients must have one of the following diagnoses based on World Heath Organization (WHO) diagnostic Aggressiv... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-999.0, Mastocytosis Any patient with a diagnosis of mastocytosis, including systemic mastocytosis and cutaneous mastocytosis and any subtypes of these diseases, who is willing and able to provide written online informed consent None | 2 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-65.0, Actinic Keratosis Are free of any systemic or dermatologic disorder, which, in the opinion of the investigator, will interfere with the study results or increase the risk of adverse events; 2. Fitzpatrick skin types I-IV (due to lack of safety data for the investigational product in d... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Myocardial Infarction Patients which, after telemedical triage, are admitted to a cardiac department in suspicions of myocardial infarction A peripheral venous catheter has been inserted prehospitally and blood has drawn from it, before flushing it Age below 18 years Patients in whi... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 3.0-17.0, Dermatitis, Atopic Patients between the ages of 3-17 experiencing a symmetric, bilateral flare of atopic dermatitis 2. The flares must reach a certain threshold for based on the investigator's global assessment scale Systemic infection or bacterial skin infections 2. Eczema herpeticum... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 3.0-999.0, Lymphoma Lymphoma, Non-Hodgkin Immune System Diseases Immunoproliferative Disorders Lymphatic Diseases Lymphoproliferative Disorders Neoplasms Neoplasms by Histologic Type Prior to Cell Procurement Informed consent explained to, understood by and signed by the subject or legal guardia... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-65.0, Acute Non-complicated Postural Neck Pain will ages of 18-64 who present with non-complicated postural neck pain, indications for cervical manipulation, including pain, decreased range of motion, and hypertonicity will discogenic pain or radicular symptoms, pregnancy, contraindication... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Steroid-refractory aGvHD Subsequent to Allogeneic Hematopoietic Cell Transplantation Patient must be ≥18years of age, males or females; 2. Patient must have been recipients of a single allogeneic HCT; bone marrow, peripheral blood and/or umbilical cord blood recipients are allowed 3.... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Type 2 Diabetes Mellitus Hypertension Active patient at McMaster Family Health Team Aged 18+ Diagnosis of Diabetes Diagnosis of Hypertension Regular access to a computer And at least ONE of Uncontrolled HbA1C measures (in the past 6 months, or most recent) Uncontrolled recent blood p... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.25-23.0, Urticaria Pigmentosa Cutaneous Mastocytosis Affected subject: Subjects will be eligible to participate in the study if all of the following conditions exist: 1. Clinical diagnosis of urticaria pigmentosa/cutaneous mastocytosis with representative skin lesions 2. Age <23 years 3. Capab... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Urothelial Carcinoma Urothelial Cancer Lung Neoplasms Small Cell Lung Cancer Prostate Cancer Phase I Patients must have advanced solid tumor that is resistant or refractory to standard therapy A minimum of 2 weeks will be required from any prior therapy, including chemotherapy, immun... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Systemic Lupus Erythematosus (SLE) Repository Corticotropin Injection Able to provide informed consent Diagnosis of SLE according to the American College of Rheumatology revised (fulfilled ≥ 4 criteria) Hematologic BILAG scores due to hemolytic anemia or thrombocytopenia of BILAG A (... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-50.0, Vitiligo To be eligible for participation, subjects must meet all of the following Must have a clinical exam consistent with and diagnosis of non-segmental vitiligo Must be normally pigmented No clinical presentation of vitiligo Outside of the specified age range No clinical diagnosi... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-65.0, Indolent Systemic Mastocytosis Provided written informed consent 2. Male or female aged ≥18 and ≤65 years at the time of signing the informed consent form 3. Confirmed diagnosis of ISM based on World Health Organization (WHO) (Appendix 1) 4. Presence of at least 1 of the following SM ... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 65.0-999.0, Chronic Disease Patient admitted to the Internal Medicine or Geriatrics department Admitted to hospital because of an exacerbation of any previous chronic condition Terminal ill patients at admission Patients with lower forecast life than 1 year Patient admitted to the hospital only... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Functional Pancreatic Neuroendocrine Tumor Malignant Somatostatinoma Merkel Cell Carcinoma Metastatic Adrenal Gland Pheochromocytoma Metastatic Carcinoid Tumor Multiple Endocrine Neoplasia Type 1 Multiple Endocrine Neoplasia Type 2A Multiple Endocrine Neoplasia Type 2B Neuroendocrine... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 12.0-999.0, Hypereosinophilic Syndrome Capable of giving signed informed consent/assent which includes compliance with the requirements and restrictions listed in the consent form and in this protocol Twelve years of age or older, at the time of signing the informed consent/assent Subjects who h... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-99.0, Neoplasm Metastasis Sarcoma Neoplasms, Germ Cell and Embryonal Melanoma Patients with bilateral pulmonary metastases from sarcomas, melanomas, germ cell tumors, or epithelial malignancies metastatic to the lungs, mediastinum, or pleura who can be rendered no clinical evidence of activ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-60.0, Systemic Lupus Erythematosus SLE diagnosis fulfilled the Systemic Lupus International Collaborating Clinic revision of the American College of Rheumatology Classification for SLE Disease stabilized ≥ 1 year ≤ 3 Anti-double strand DNA negative by IF measurement and ≤ 200IU/ml by ELISA ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Gout >/= to 18 yrs of age with Current physician diagnosed gout current hyperuricemia (serum urate level >6.8 mg/dl) self-report of at least two gout flares in the previous 6 months current smartphone user utilizing a FitBit compatible smart Phone (with the ability to download RheumP... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-75.0, Systemic Auto-immune Diseases Quality of Life For all patients Patients aged 18 to 75 years Patients able to understand written and spoken French Patients who have been given oral and written information about the research For patients with SLE SLE defined by American College of Rheum... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-55.0, Hepatitis B, Chronic Hepatitis D, Chronic Signed written informed consent Any patients not enrolled in the REP 301 protocol or not successfully completing all treatment and follow-up visits in the REP 301 protocol 2. A history of alcohol abuse within the last year 3. The use of illic... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 1.0-31.0, B Acute Lymphoblastic Leukemia Central Nervous System Leukemia Ph-Like Acute Lymphoblastic Leukemia Testicular Leukemia Patients must be enrolled on APEC14B1 and consented to Screening on the Part A consent form prior to enrollment on AALL1131 White Blood Cell Count (WBC) Age 1-9.99 ye... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Pancreatic Neuroendocrine Tumor G1 Pancreatic Neuroendocrine Tumor G2 Refractory Pancreatic Neuroendocrine Carcinoma Patients must have unresectable or metastatic, histologically confirmed low or intermediate grade (Klimstra Criteria) pancreatic neuroendocrine tumor (PNET) with radio... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Eating Disorders Primary diagnosis: eating disorder according to DSM IV (Diagnostic and statistical manual of mental disorders fourth edition) based on diagnostic interview Illness duration of ED >10 Participated in at least three failed specialized eating disorder treatments Written... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-65.0, Chronic Graft-versus-host Disease Written informed consent Male not pregnant female patients <65 years old Diagnosis of cGVHD steroid refractory (no response after Prednisone ≥1mg/kg ) or steroid-dependent cGVHD (had an initial response followed by a cGVHD flare upon steroid taper) Pat... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-60.0, Systemic Lupus Erythematosus Meet the American College of Rheumatology for the diagnosis of SLE Under standard treatment (≥ 2 months) at the time of Background treatment failed to control flares or to permit prednisone tapering With at least one of the following manifestations: thromb... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Acute Urticaria Male or female patients with a diagnosis of acute urticaria who need treatment with antihistamine to alleviate their symptoms; 2. 18 years of age or older; 3. Be willing and able to give informed consent; 4. Patients with a Patient rated Pruritus Severity Score ≥ 1 R... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-65.0, Lupus Nephritis Active lupus nephritis Fulfill ACR classification (2009) for SLE Proteinuria ≥1g/24h at screening Nephritis of class III, IV, V, III+IV or IV+V, confirmed by renal pathology within 90 days prior to screening Body weight ≥40kg SLE-2K score ≥8 Agreement of contraception ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Infection Systemic Age ≥ 18 years Signed informed consent Assumed or proven infection Patient admitted to the unit participating in the study Patients with severe immunosuppression, such as severe neutropenia (<500 neut/mm3), transplantation of solid organs or cells hematopoietic, H... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 3.0-15.0, Nephrotic Syndrome Steroid-Dependent Interleukin 2 Children between 3 and 15 years of age (included) with a steroid responsive idiopathic nephrotic syndrome Idiopathic nephrotic syndrome progressing for less than 1 year Steroid dependent idiopathic nephrotic syndrome (at least 1 relaps... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-999.0, Smoking Oxygen Deficiencies Sixty patients undergoing lobectomy using one lung ventilation by double lumen tube, ASA physical status 2 and 3 Recent chest infection, morbid obesity, renal, hepatic and ischemic hearts disease, asthma | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-55.0, Diabetes Mellitus The patient is a pregnant female 18 years of age or older 2. The patient has been diagnosed with gestational diabetes or is a patient with known diabetes and a confirmed viable pregnancy 3. The pregnancy has a singleton pregnancy 4. The patient has access to a cellul... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Leukemia, Myelomonocytic, Chronic ≥18 years of age at the time of signing the informed consent form CMML-1 with indication for treatment according to NMDSG guidelines* Life expectancy of more than three months and ability to undergo routine outpatient evaluations for efficacy, safety... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Pelvic Organ Prolapse Urinary Incontinence,Stress Surgery Female patients Over 18 years old Speak English and are capable of giving informed consent and are able to complete the English patient questionnaire Are willing to return to the office for all necessary visits associated with... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-99.0, Systemic Lupus Erythematosus Arthritis Adults aged at least 18 years old Active musculoskeletal SLE defined by inflammatory musculoskeletal pain with either clinical synovitis, ultrasound tenosynovitis or positive power Doppler in at least 1 joint No contraindication to the use of IV ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-80.0, Colitis, Ulcerative Colitis Ulcerative Exacerbation Willingness to comply with all trial procedures and being available for the duration of the trial Clinically and histologically verified ulcerative colitis eligible for treatment with thiopurines due to steroid dependence (failure to... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Transplant Dysfunction Magnesium Disorder Kidney transplant recipients who used only proton pump inhibitors and did not use histamine H2 receptor antagonists (Only PPI) Kidney transplant recipients who used histamine H2 receptor antagonists and did not use proton pump inhibitors (Onl... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-75.0, Urticaria Aged 18-75 years, inclusive Diagnosis of chronic spontaneous urticaria (CSU) refractory to H1 antihistamines at the time of randomization Willing and able to complete an Urticaria Participant Daily eDiary for the duration of the study No evidence of active or latent or inade... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Urinary Retention Voiding Disorders Females at least 18 years of age Understand and voluntarily sign an informed consent form English-speaking (able to read and understand English) Undergoing total laparoscopic hysterectomy for benign indication Undergoing concomitant procedures in ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Facial Papulopustular Rosacea Moderate-to-severe rosacea (as per the IGA score) on the proposed facial treatment area consisting of: 1. At least 15 and not more than 75 facial papules and pustules, excluding lesions involving the eyes and scalp; 2. No more than 2 nodules on the face.... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 21.0-99.0, Relapse and / or Refractory Myeloma Multiple myeloma, diagnosed according to standard with relapsing and refractory disease at study entry 2. Patients must have evaluable multiple myeloma with at least one of the following (within 21 days of starting treatment) 1. Serum M-protein ≥ 0.... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-45.0, Urinary Tract Infections (UTI's) pre-menopausal women present with an acute, uncomplicated, culture confirmed UTI, defined as dysuria, urgency and/or frequency at least one previous medically diagnosed UTI in past 12 months using a reliable method of birth control ie: history of tubal... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Inflammatory Disorder Autoimmune Informed Consent as documented by signature (Appendix Informed Consent Form) Age ≥ 18 years Daily glucocorticoid dose ≥ 7.5 mg prednisone-equivalent at the time of Therapy over ≥ 28 days, ≥ 7.5 mg average daily dose, with a cumulative glucocorticoid d... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 7.0-999.0, Drug Hypersensitivity Penicillin Allergy Antibiotic Allergy All patients seven years of age or older who have a low-risk, non-life-threatening history of adverse reaction to an antibiotic Patients under the age of seven Pregnant patients Patients with a history of a drug reaction tha... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Colitis, Ulcerative Age>18 years Voluntary to participate to the study Flare-up of ulcerative colitis with Mayo score >6 Ability to receive steroid or anti-TNF therapy Agree the rectosigmoidoscopy and the therapies Age <18 years Pregnancy Disagree the rectosigmoidoscopy or the thera... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 6.0-999.0, Lupus Erythematosus, Systemic Patient aged ≥ 6 years Patient who met the American College of Rheumatology (ACR) or the Systemic Lupus International Collaborating Clinics Classification (SLICC) for systemic lupus erythematosus Patients needs (re)initiation of oral prednisone regimen at... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-75.0, Diffuse Large B Cell Lymphoma Diagnosed as diffuse large B-cell Lymphoma with positive CD20 results; 2. Age between 18 to 75 years old; 3. World health organization-Eastern Cooperative Oncology Group Performance Status (ECOG) 0-2; 4. No history of malignant tumors, having no tumor oth... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Infection Heart Failure COPD Asthma Gout Flare Chronic Kidney Diseases Hypertensive Urgency Atrial Fibrillation Rapid Anticoagulants; Increased Resides within either a 5-mile or 20 minute driving radius of emergency department Has capacity to consent to study OR can assent to study a... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Gastroesophageal Reflux > 18 years old Male or female PPI on home medication reconciliation GERD that is symptom controlled (per questionnaire), OR Gastritis that is symptom controlled (per questionnaire), OR An unclear indication for PPI use but free of GERD/gastritis/ulcer symptoms... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Chemotherapy-induced Nausea and Vomiting No prior chemotherapy Confirmed malignancy, scheduled to receive carboplatin monotherapy, or carboplatin in combination with agents of minimal, low, or moderate emetic potential Laboratory parameters adequate for chemotherapy Patients with Ea... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Osteoarthritis, Knee Patients of co-investigator physicians Age 18+ years Diagnosis of symptomatic knee osteoarthritis Scheduled for a hyaluronic acid injection into the knee Provider is available to administer teaching method Patients who are already enrolled in the study Non-Engli... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Stroke have had a stroke (ischemic or hemorrhagic) resulting in physical impairment; 2. have enough preserved cognitive ability to learn VRT 3. are receiving inpatient or outpatient stroke rehabilitation services; 4. are able to stand independently for at least 2 minutes 5. have a st... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Adult-Onset Still Disease Critically Ill AOSD (history of newly diagnosed) ICU admission between January 2001 and June 2017 adults under protection admission in step-down unit | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Vaginal Laxity Urinary Incontinence Sexual Dysfunction Healthy female adult subjects presenting, clinically, with VL, and has expressed interest in treatment will be considered eligible for the study. Enrollment of subject will depend on meeting the following Voluntarily signed infor... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Osteoarthritis, Knee Osteoarthritis, Hip Key (additional may apply at screening): 1. A clinical diagnosis of osteoarthritis (OA) of the knee or hip based on the American College of Rheumatology with radiologic evidence of OA (K-L score ≥2 for the index joint) at the screening visit. ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-999.0, Dysphasia Patients undergoing a primary 1 to 2-level MIS TLIF Diagnosis: myelopathy, radiculopathy, myeloradiculopathy, stenosis, herniated nucleus pulposus, degenerative disc disease, spondylosis, osteophytic complexes, and foraminal stenosis Patients able to provide informed consent... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.5-16.0, Food Allergy Food Allergy in Infants Food Allergy in Children Food Allergen Sensitisation Milk Allergy Egg Allergy Nut Allergy Children ≥6 months and <16 years old; 2. Suspected IgE-mediated food allergy defined by History of an immediate-type allergic reaction to a specific food or No... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Systemic Lupus Erythematosus Subjects must be >=18 years of age at the time of signing the informed consent Subjects who have clinical diagnosis of SLE based on 4 or more of the 11 American College of Rheumatology (ACR) criteria Subjects who have a screening score >=6 (This refers to... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Pain, Postoperative Patients undergoing hysterectomy Coronary Artery Disease Peptic Ulcer Disease Chronic Renal Disease Liver disease Alcohol Abuse Daily narcotic usage Narcotic use 24 hours prior to surgery Crohn's Disease History of myocardial infarction History of stroke | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-65.0, Analgesia Patients of either sex undergoing elective tota knee replacement surgery Patients are capable to provide an informed consent Age 18-65 years Patients with Asthma, copd or any other respiratory disease Persistent nausea , vomiting at the time of randomization Treated with MA... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Autism Spectrum Disorder People who are awaiting an ASD assessment at the host site People who have never visited the site before People who do not receive a diagnosis of ASD following the study will not be included in the inferential statistical analysis. However, they will still b... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Osteoporosis Systemic Mastocytosis Male or female >/= 18 years of age at time of informed consent Willingness and ability to sign informed consent, comply with scheduled visits, treatment plan, laboratory tests and other study procedures Patient with Indolent systemic or cutaneous ma... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 20.0-80.0, Compare the Response Rate of Atypical GERD After PPI Therapy atypical GERD symptoms (cough, globus, or NCCP) 2. with or without typical GERD symptoms (heartburn or acid regurgitation) 3. A total Reflux Symptom Index (RSI) score ≥13 Patients who currently took pro-kinetic agents, bacl... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Cardiotoxicity HER2/Neu Positive Metastatic Malignant Neoplasm in the Brain Recurrent Breast Carcinoma Stage IV Breast Cancer AJCC v6 and v7 STEP 1 Patients must have metastatic breast cancer and be initiating within 7 days of step 1 registration or continuing trastuzumab?based HER-2... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-44.0, Plasma Volume Micronutrients Menstrual Cycle Female to 44 years of age General good health (does not have a known, ongoing health condition/medical issue that requires regular monitoring by a doctor or regular visits to the hospital) BMI 18.5-24.9 kg/m2 Regular menstrual cycle (26-35 ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, System; Lupus Erythematosus ≥ 18 years of age who can consent for themselves Location U.S Proficient in English (speaking, reading, and writing) Own or have reliable access to a smartphone (iPhone or Android) Provision of medical record Diagnosis of Lupus SLE as indicated in medical ... | 0 |
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