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Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Chronic Spontaneous Urticaria Patients with active CSU for at least 4 months which was treated with anti-histamines as well as at least one course of steroids (ex. Prednisone) Age ≥18 years Patients will undergo an ECG and QT parameters will be measured for further analysis Female su... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, T-LGL Leukemia Clpd-Nk The gender of the patient is not limited, and the age is ≥18 years old; 2. Must meet diagnostic of T-LGLL or CLPD-NK according to WHO 2016 version; 3. The patient is treatment naive or received single methotrexate less than 4 weeks and without response. If rela... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-65.0, Addiction Opiate Chronic Pain Fractures, Bone Buprenorphine Dependence Orthopaedic trauma patient with history of suboxone use for greater than 30 days. Trauma must involve major long bone fracture(s) (femur, tibia, fibula, humerus, radius, ulna) 2.Must have taken suboxone in the last... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-65.0, Dry Eye Patients with Sjögren's syndrome, both in primary and secondary forms, whose diagnoses were established according to the defined by the American-European Consensus for the diagnosis of Sjögren's syndrome Patients with the secondary form of the syndrome, collagen disease consid... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 21.0-60.0, Thyroid Diseases Patient acceptance. BMI < 35kg/m2. ASA I and ASA II. Scheduled for elective thyroidectomy under general anesthesia Patient refusal. History or anticipated difficult intubation. Chronic respiratory disease such as chronic obstructive pulmonary disease or asthma. Recen... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 20.0-45.0, Thermal Burn Age ranged between 20 and 45 years Deep 2nd degree of thermal burn of lower limb and trunk with (35-40%) surface area of burn as measured by "rule of nine" method, with complete wound healing or after 6 weeks from the injury Body mass index of between 17 and 35, with no h... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-999.0, Patients Undergoing Elective Surgery With Anesthesia ≥18 years estimated ASA I/II classification based on the American Society of Anesthesiologists (ASA) classification elective surgery surgery at least 14 days in the future patient access to a Windows-10-based personal computer with ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Myocarditis Ventricular Arrythmia Inflammatory Cardiomyopathy Genetic Predisposition Autoimmunity Arrhythmia Cardiomyopathies Immunosuppression Catheter Ablation Written informed consent Age ≥ 18 years Clinically suspected myocarditis Enrollment performed by one of the participating ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, COVID-19 Inclusion/ for INDEX CASES: 1. Adults aged 18 years or older who are newly diagnosed with COVID-19 infection within 7 days of testing. 2. Ability and willingness to understand and provide informed consent Known current pregnancy. 2. Current hospitalization. 3. Unable to com... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Clinical Stage III Human Papillomavirus (HPV)-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Locally Advanced Head and Neck Squamous Cell Carcinoma Locally Advanced Hypopharyngeal Squamous Cell Car... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Clinical Trial Proven cases of COVID-19 infection by real-time polymerase chain reaction (PCR) of the nasopharyngeal and oropharyngeal swabs and presented with recent onset of anosmia alone or with ageusia or other symptoms of the disease were enrolled in the current study. - Patien... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Breast Cancer Melanoma Thoracic Cancer Lymphedema of Upper Arm History of bilateral or unilateral axillary SLNP (sentinel biopsy, lymphadenectomy or dissection) and a previous or current failed contralateral IV attempt or at the discretion of the treating radiologist, a participant w... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 3.0-24.0, Nephrotic Syndrome Steroid-Dependent Age between 3 and 24 years Prednison dependent steroid syndrome 0.3-1mg/Kg/day and receive prednisone for at least six months before enrolment. Steroid dependence is defined by two consecutive relapse during corticosteroid therapy or within 14 days ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 16.0-30.0, Orthodontic Appliance Age ≥ 16 years Proclined upper and lower incisors (Ui/max >115 o, Li/mand >99o) Mild upper and lower arch crowding (<4mm) or no crowding Need for upper and lower first premolars extraction Skeletal I malocclusion (1<ANB <5) Average lower facial height and maxillo... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 40.0-70.0, Coronary Artery Disease Asymptomatic subjects age 40-70y 2. Statin naïve 3. TC ≤ 6.5 mmol/L and LDLC <5 mmol/L, and 4. 5 year Australian risk ≥2% Symptomatic coronary, cerebrovascular, or peripheral vascular disease 2. Intolerance of statins or currently on statins for any length of ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Peritonitis Age ≥ 18 years 2. Patients operated for purulent or fecal peritonitis (Hinchey grade III and IV) secondary to perforated diverticulitis of the left colon and treated by resection with primary anastomosis 3. Person informed and having signed his consent. If the patient is ... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Facial Papulopustular Rosacea Moderate-to-severe rosacea (as per the IGA score) on the proposed facial treatment area consisting of: 1. At least 15 and not more than 75 facial papules and pustules, excluding lesions involving the eyes and scalp; 2. No more than 2 nodules on the face.... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Irritable Bowel Syndrome Dermatographism Post-prandial Diarrhea Age 18 years and older Prior to Diagnosis of IBS + diarrhea based on ICD 10 codes with or without constipation unresponsive to prior treatments Moderate to severe symptom severity score (>175 points) based on IBS symptom... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 1.5-5.417, Mastocytosis Cutaneous Adult patient (> 18 years old) with confirmed mast cell disorder according to international Patient affiliated to social security regime Patient under legal protection (guardianship, curators or court order) Patient does not speak French | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 35.0-65.0, Obstructive Sleep Apnea Heart Rhythm Disorder Obesity, Abdominal gender: female or male age 35-65 years old visceral obesity lack of acute or chronic diseases that may have an influence on rhythm or conduction disorders not undergoing Continuous Positive Airway Pressure therapy (CPAP)... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-90.0, Covid19 Coronavirus Infection SARS-CoV Infection Patients with COVID-19 typical symptoms (cough, fever, anosmia) present for not more than 96 hours. 2. 18 years or older. 3. No use of ivermectin prior to the study. 4. No known history of ivermectin allergy. 5. The patient can give his... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 60.0-90.0, Alzheimer Disease Dementia Brain Diseases Central Nervous System Diseases Cognitive Impairment Participated in a double-blind treatment period of a sponsor-approved originating donanemab trial, for example the study Have a study partner Stable symptomatic Alzheimer's Disease (AD) medi... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, High-dose Steroids, Myocardial Function, Longitudinal Strain Age above 18 Patient with rheumatic disease that need high dose steroids due to exacerbation Patient whom echocardiographic study can be performed with a good quality age below 18 | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Primary Sclerosing Cholangitis In order to be eligible to participate in this study, an individual must meet all of the following 1. Stated willingness to comply with all study procedures and availability for the duration of the study 2. Male or nonpregnant female, greater than or eq... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Advanced Systemic Mastocytosis Aggressive Systemic Mastocytosis Systemic Mastocytosis With an Associated Hematological Neoplasm Mast Cell Leukemia for Patients in the External Control Arm: 1. Diagnosed with AdvSM, with known subtype including SM-AHN, ASM, or MCL 2. Received at least ... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 12.0-999.0, Advanced Systemic Mastocytosis Aggressive Systemic Mastocytosis Systemic Mastocytosis With an Associated Hematological Neoplasm Mast Cell Leukemia Patients who are ≥ 15 years of age, or ≥ 12 years of age AND ≥ 35 kg. 2. Patients must have a diagnosis of advanced systemic mastocytosis... | 1 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 0.0-999.0, Anaphylaxis Biphasic Anaphylactic Reaction Rebound Anaphylactic Reaction Patients of all ages with anaphylaxis (meeting the NIAID/FAAN criteria) Patients of all ages considered to be inevitably evolving torwards overt anaphylaxis by the threading physician Adverse reaction to a medic... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Death, Sudden Ventricular Tachycardia Implantable Defibrillator User Myocardial Infarction Myocardial Dysfunction AMI patients over 18 years old LVEF equal or lower than 40% determined by a transthoracic echocardiography 4 days after the onset of the AMI Revascularization during hosp... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Acute Graft Versus Host Disease in Intestine Steroid Refractory GVHD Age ≥ 18 years old Allo-HSCT with any type of donor, stem cell source, GVHD prophylaxis or conditioning regimen Acute GvHD episode with GI involvement per MAGIC guidelines (= grades II to IV), with or without involv... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Infection Heart Failure Chronic Obstructive Pulmonary Disease Asthma Gout Flare Chronic Kidney Diseases Hypertensive Urgency Atrial Fibrillation Rapid Anticoagulants; Increased Was a subject in the Brigham and Women's Home Hospital study and has a completed record in the study's data... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Sjögren Syndrome Sicca Syndrome Agreement to participate in the study according to signed informed consent Filling the pSS classification criteria Absence of other autoimmune associates systemic diseases EULAR Sjögren Syndrome Disease Activity Index (ESSDAI) <= 5 Prednisone dose < 20... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Systemic Mast Cell Activation KIT D816V Mutation Presenting with at least one of the three below as evidence of systemic mast cell activation: 1. Involvement of 2 or more organ systems, characterized by skin (pruritus, urticaria, flushing and angioedema), cardiovascular (tachycardia,... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Liver Cirrhosis Liver Tumor Liver Transplant Failure and Rejection age >18 years deceased-donor liver transplantation provision of informed consent donation after cardiac death either reduced or split graft | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-70.0, Attention Deficit Hyperactivity Disorder The participant has provided signed informed consent. 2. Males and/or females aged 18-70 (extremes included). 3. Participants with a primary diagnosis of ADHD according to DSM-5 (314.01) (diagnosis to be made using the Mini-International Neurop... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 18.0-999.0, Gout Chronic Kidney Disease Renal Transplantation Adults aged over 18 years old Gout confirmed by identification of urate crystals by joint fluid or tophus analysis or by ultrasound of the affected joint or Gout according to Nijmegen (presence of a score ≥ 8/13) depending on the foll... | 0 |
Pt is a 22yo F otherwise healthy with a 5 yr history of the systemic mastocytosis, with flares normally 3/year, presenting with flushing and tachycardia concerning for another flare. This is patient's 3rd flare in 2 months, while still on steroid taper which is new for her. She responded well to 125 mg IV steroids q 8 ... | eligible ages (years): 4.0-55.0, Food Allergy Age 4 to 55 (inclusive) Clinical history of allergy to at least 1 of the foods contained in ADP101 Experience dose-limiting symptoms at or below the 100-mg dose level to 1 or multiple food sources in ADP101 Experience dose limiting symptoms at or below the 100 mg challeng... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 0.5-999.0, Hurthle Cell Thyroid Cancer Tall Cell Variant Thyroid Cancer Follicular Thyroid Cancer Thyroid Cancer Papillary Thyroid Cancer In order to be eligible to participate in this study, an individual must meet all of the following 1. Male or female, adults or children >= 6 months+. 2. Pati... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Islet Cell Adenoma Zollinger Ellison Syndrome Subjects selected for this study will be patients with Zollinger-Ellison syndrome who are being evaluated under the protocol entitled "Diagnostic evaluation of patients with suspected abnormalities of gastric secretion" (80-DK-123). To be... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 0.0-999.0, Head and Neck Neoplasm Squamous Cell Carcinoma Patients must satisfy the following The patient must have a biopsy proven diagnosis of carcinoma of the oral cavity, oropharynx, hypopharynx, nasopharynx, larynx, maxillary sinus. Squamous cell, lymphoepithelioma, transitional cell and un... | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 0.0-999.0, Hypothyroidism Thyroid Neoplasms Patients greater than or equal to 18 years of age, with well-differentiated, non-medullary thyroid cancer, including papillary (including follicular-variant), follicular, and Hurthle cell. Patients who recently have undergone a total or near-total thyr... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Head and Neck Cancer Biopsy-proven squamous cell carcinoma of one of the following sites: Hypopharynx Larynx Oral cavity Oropharynx At least 1 of the following high-risk factors required: Histologic extracapsular nodal extension Histologic involvement of 2 or more regional lymph node... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 16.0-999.0, Breast Cancer Histologically confirmed metastatic breast cancer Bidimensionally measurable disease of any of the following types required: Bidimensionally measurable lung lesions on chest X-ray, CT scan, or MRI Palpable and quantifiable lymph nodes at least 2 x 2 cm Abdominal mass at... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Head and Neck Cancer Histologically confirmed recurrent, refractory, or second primary squamous cell cancer of the head and neck that is incurable with surgery or radiotherapy Any N, Any M, single or multiple tumor(s) Locally accessible, discrete tumor(s) by CT or MRI scan Must be co... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 0.0-999.0, Head and Neck Cancer Radiologically confirmed persistent or metastatic follicular or papillary thyroid cancer following total thyroidectomy and radioiodine ablation therapy Metastatic disease confirmed histologically or cytologically or by elevated thyroglobulin levels No radioiodine ... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-120.0, Head and Neck Cancer Histologically confirmed follicular, papillary, insular, or medullary thyroid carcinoma Must meet for 1 of the following Unresectable, distantly metastatic tumor that does not concentrate radioactive iodine Follicular or papillary thyroid carcinoma with a large d... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 25.0-80.0, Stiff-Person Syndrome All patients who fulfill the recently revised clinical for SPS Lack of anti-GAD antibodies in the serum; Very advanced disease state that precludes traveling; Severe cardiovascular, renal, or other end-organ-disease states | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-120.0, Carcinoma of Unknown Primary Histologically confirmed squamous cell carcinoma in cervical lymph node metastasis from an unknown primary tumor Histopathological grade WHO 1-3 Pathological stage N1, N2a, N2b, or N3 No N2c (i.e., bilateral metastatic nodes) No single node in supraclavic... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Cervical Cancer Fallopian Tube Cancer Ovarian Cancer Primary Peritoneal Cavity Cancer Histologically confirmed ovarian epithelial cancer or cervical cancer (open to accrual for cervical cancer patients only as of 4/5/2005) Relapsed or refractory The following are also eligible: (open... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Head and Neck Cancer Histologically confirmed* anaplastic or poorly differentiated variant thyroid cancer, including 1 of the following Recurrent/regionally advanced disease no longer amenable to definitive curative surgery or radiotherapy Untreated metastatic disease NOTE: *If origi... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Head and Neck Cancer Histologically confirmed thyroid carcinoma, including 1 of the following subtypes Papillary Follicular Hurthle cell Insular Assessable disease, defined by at least 1 of the following Metastatic (including neck lymph nodes) measurable disease At least 20 mm by con... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Colorectal Cancer Head and Neck Cancer Metastatic Cancer Histologically or cytologically confirmed solid tumor of 1 of the following malignant tumor types Squamous cell cancer of the head and neck Thyroid cancer Liver metastases* secondary to colorectal adenocarcinoma NOTE: *Liver me... | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Head and Neck Cancer Histologically confirmed anaplastic or poorly differentiated variant thyroid carcinoma of either of the following Regionally advanced disease Confined to the neck and/or superior mediastinum (i.e., above the level of the carina) Measurable or evaluable* disease C... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Head and Neck Cancer Diagnosis of squamous cell carcinoma of the head and neck Selected stage III or IV (no distant metastasis) disease The following TNM stages are excluded T3, N0, M0 T4a, N0, M0 T4b, N3, M0 Any T, any N, M1 Complete total resection within the past 56 days AND has o... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Recurrent Thyroid Cancer Stage IVA Follicular Thyroid Cancer Stage IVA Papillary Thyroid Cancer Stage IVB Follicular Thyroid Cancer Stage IVB Papillary Thyroid Cancer Stage IVC Follicular Thyroid Cancer Stage IVC Papillary Thyroid Cancer Histologically confirmed papillary thyroid or ... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Recurrent Head and Neck Cancer Metastatic Head and Neck Cancer Histologically or cytologically confirmed squamous cell carcinoma of the head and neck; patient must not have nasopharyngeal carcinoma of histologic types World Health Organization (WHO) 2 and 3 Metastatic or locally recu... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Thyroid Neoplasms Histologically documented thyroid cancer with metastases Failure of radioactive iodine (131I) to control the disease or radioactive iodine (131I) is not an appropriate therapy (e.g. due to lack of iodine uptake by the tumor) Central lung lesions involving major blo... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-120.0, Head and Neck Cancer Histologically confirmed medullary thyroid cancer Metastatic or inoperable locoregional disease Measurable disease by CT scan years and over ECOG PS 0-1 Adequate lab functions including Granulocyte count > 1,000/mm^3 Platelet count > 100,000/mm^3 Bilirubin < 1.5 ... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 21.0-999.0, Head and Neck Cancer Cytologically confirmed papillary thyroid cancer by fine needle aspiration Low-risk disease No poorly differentiated cytology Intrathyroidal tumor Located within the anterior two-thirds of the thyroid lobe Tumor not adjacent to the trachea by neck ultrasound Tumo... | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Thyroid Neoplasms Total or near total thyroidectomy performed for papillary or follicular thyroid cancer R0-1 resection, no macroscopic cancer left behind at surgery Physically and emotionally able to undergo radioiodine treatment A written informed consent Pregnancy Physical or psy... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Stroke Malnutrition Weight Loss Dysphagia Acute stroke based on clinical symptoms years old and above < 7 days since debut of stroke symptoms and either body mass index (BMI) = or < 20 Weight loss > 5% in 3-6 months or there has been little or is likely to be no or very little nutrit... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 0.0-999.0, Head and Neck Neoplasms actual or suspected malignant or non-malignant tumors of the head and neck planned biopsy and/or resection, or availability of paraffin embedded or stored frozen tumor tissue for non-genetic analysis insufficient tissue available for both standard diagnostic e... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 16.0-999.0, Thyroid Cancer Differentiated Thyroid Carcinoma Patients older than 16 years with well-differentiated papillary or follicular thyroid cancer stage I or II, according to the classification at time of surgery 2. Patients younger than 45 years with any size of primary papillary or folli... | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Head and Neck Cancer All subjects must have histologically or cytologically confirmed diagnosis of squamous cell carcinoma of the head and neck region. Primary tumor sites oral cavity, pharynx (oropharynx, hypopharynx), or larynx (supraglottis, glottis subglottis). Nasopharynx primar... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Metastatic Hormone-sensitive Prostate Cancer Histologically or cytologically confirmed prostate cancer Metastatic disease On androgen-deprivation therapy for < 120 days Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0-2 PS 2 eligible only if decline in PS is due to... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Head and Neck Cancer All patients must have histologically or cytologically confirmed carcinoma of the head and neck region. Primary tumor sites lip and oral cavity, major salivary glands, pharynx (oropharynx, nasopharynx, hypopharynx), or larynx (supraglottis, glottis, subglottis), ... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Gastroesophageal Reflux Main Written informed consent Inpatients (hospitalization during the entire study period is mandatory) Symptomatic (heartburn, acid regurgitation or dysphagia for at least 1 day since admission to the hospital) non-erosive reflux disease (NERD) or erosive gast... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Joint Pain Musculoskeletal Pain Stiffness Soft Tissue Inflammation in Designated Target Area(s) at least 18 years or older agree to refrain from chronic usage of NSAIDs or any other analgesics or anti-inflammatory drugs other than those provided during the course of the study or docu... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Head and Neck Cancer years or older Diagnosed with head and neck cancer including the lip, oral cavity, salivary glands, paranasal sinuses, oropharynx, nasopharynx, hypopharynx, larynx, and thyroid All histological types of cancer All tumour stages according to American Joint Committ... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Differentiated Thyroid Gland Carcinoma Recurrent Thyroid Gland Carcinoma Refractory Thyroid Gland Carcinoma Stage III Thyroid Gland Follicular Carcinoma AJCC v7 Stage III Thyroid Gland Medullary Carcinoma AJCC v7 Stage IV Thyroid Gland Follicular Carcinoma AJCC v7 Stage IV Thyroid Gl... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Thyroid Cancer Confirmed diagnosis of unresectable, locally advanced or metastatic hereditary or sporadic Medullary Thyroid Cancer Presence of measurable tumor Able to swallow medication Major surgery within 4 weeks before randomization Last dose of prior chemotherapy received less ... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 16.0-80.0, Head and Neck Cancer Histologically confirmed differentiated thyroid cancer T1-T3, Nx, N0, N1, M0 disease Has undergone one or two-stage total thyroidectomy with or without lymph node dissection All known tumor resected (R0) Requires radioiodine remnant ablation Does not require manda... | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-100.0, Head and Neck Cancer Diagnosis of thyroid cancer Measurable disease by CT scan or nuclear medicine imaging Eligible, by standard of care for iodine I 131 therapy Not pregnant or nursing Negative pregnancy test Fertile patients must use effective non-barrier method contraception (e.g.... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 0.0-999.0, Differentiated Thyroid Carcinoma Hiostologically proved DTC (M0) Preoperative metastasis | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 10.0-90.0, Thyroid Neoplasms Papillary thyroid cancer diagnosed in NTUH from 1977 to 2000 Patient without complete medical record | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-99.0, Tumor Cancer cancer which is refractory to standard therapies WHO performance status 0-2 evidence of post-menopausal status or negative pregnancy test Radiotherapy/chemotherapy within 21 days prior to entry brain metastases/spinal cord compression unless stable off steroids/anticonvu... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 0.0-999.0, Hemorrhage Hypocalcemia Vocal Cord Palsy patients with total thyroidectomy plus central neck dissection if primary tumor size was more than 1 cm in papillary thyroid cancer there was any evidence of lymph node enlargement in paratracheal lymph node group preoperatively or intraoperati... | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 30.0-70.0, Obesity BMI between 30-40 Age between 30-70 At least moderately interested in losing weight (Self-reported 3,4, or 5 on 5 point scale) Unstable medical conditions that would likely prevent the subject from completing the study Myocardial infarction within 6 months Uncontrolled hypert... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 40.0-80.0, Patients Undergoing High Risk PCI. Signed Informed Consent Non emergent PCI of at least one de novo or restenotic lesion in a native coronary vessel or bypass graft EF <35% ST Myocardial Infarction Cardiac Arrest Cardiogenic Shock Thrombus Left Ventricle | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Thyroid Neoplasms Previously confirmed histological diagnosis of locally advanced or metastatic papillary or follicular thyroid carcinoma, without anaplastic component. Tumor sample available for centralized exploratory analysis Presence of one or more measurable lesions at least 1 c... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Recurrent Thyroid Gland Carcinoma Stage I Thyroid Gland Papillary Carcinoma Stage II Thyroid Gland Papillary Carcinoma Stage III Thyroid Gland Papillary Carcinoma Stage IV Thyroid Gland Papillary Carcinoma Histologically or cytologically confirmed papillary thyroid cancer or papillar... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-120.0, Head and Neck Cancer * Histologically or cytologically confirmed diagnosis of recurrent or second primary squamous cell carcinoma (SCC) of the head and neck, including any of the following Oral cavity Oropharynx Hypopharynx Larynx Recurrent neck metastases with unknown primary Except... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Esophagitis Inflammation Gastritis Abdominal Pain Heartburn Patients referred for upper endoscopy for any reason including those with acid reflux, dyspepsia, weight loss, Barrett's esophagus,suspected Helicobacter pylori infection. 2. Patients able to provide written informed consent... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Blood Pressure Cardiac Transplantation s/p cardiac transplantation scheduled for clinical right heart catheterization age > 18 years significant tricuspid regurgitation inability to safely swallow 500 ml of water other major medical comorbidities such as advanced renal disease where... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Dysphagia complaints of dysphagia scheduled to undergo videofluoroscopy able to tolerate both videofluoroscopic evaluation of swallowing and FEES age less than 18 contraindications to videofluoroscopy (reaction to barium, possible pregnancy) contraindications to FEES (bilateral obst... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, CNS Brain Metastasis Head and Neck Cancer Lung Cancer Prostate Cancer Esophageal Cancer Able to tolerate a PET/CT scan Age of 18 or older signed informed consent being considered for radiotherapy for treatment of CNS mets, Head and neck cancer, lung cancer, prostate cancer or esophag... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 1.0-999.0, Thyroid Cancer Age 1 Benign or malignant thyroid lesion, other malignancy or no thyroid abnormality Pathologic specimen available for analysis Ability to provide informed consent (for prospective study, Part Two) Age greater than age 18 (for normal controls) Patients without adequate... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-75.0, Thyroid Cancer Follicular or papillary thyroid cancer < 18 or > 75 years old Pregnant or lactating women | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 0.0-999.0, Thyroid Nodule Thyroid Cancer Thyroid Neoplasms Nodular Goiter Histologically or cytologically documented benign thyroid nodule, or cold thyroid nodule as documented by thyroid scan Patient has been evaluated by endocrinology and endocrine surgery and has been deemed suitable candidat... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 19.0-999.0, Recurrent Thyroid Gland Carcinoma Stage III Differentiated Thyroid Gland Carcinoma AJCC v7 Stage III Thyroid Gland Medullary Carcinoma AJCC v7 Stage IVA Differentiated Thyroid Gland Carcinoma AJCC v7 Stage IVA Thyroid Gland Anaplastic Carcinoma AJCC v7 Stage IVA Thyroid Gland Medulla... | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 21.0-999.0, Dysphagia Male or female ages 21+ At least 3 months post-radiation therapy for head & neck cancer Treatment for their cancer can chemotherapy Surgery for their cancer, if done, must meet these diagnostic biopsy less than ½ of oral tongue resected less than ½ of tongue base resected n... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 15.0-85.0, Hypocalcemia Differentiated papillary thyroid carcinoma Undergoing total thyroidectomy plus central neck dissection Previous thyroid or neck surgery Patients with parathyroid diseases Other thyroid malignancies Early loss of follow-up without proper evaluation of postoperative serum ... | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-80.0, Head and Neck Squamous Cell Carcinoma Biopsy-proven HNSCC Clinical stage: unpreviously treated T1-T4 oral cavity, oropharynx, hypopharynx, larynx Only patients suitable for at least a neck dissection after chemoradiotherapy will be included. Consequently, are thus : T1-T4 , N1 N2a, N2... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 6.0-999.0, Cystic Fibrosis Lung Infection Pseudomonas Aeruginosa Participants ≥ 6 years of age Documentation of CF diagnosis as evidenced by one or more clinical features consistent with the CF phenotype and one or more of the following Sweat chloride ≥ 60 mEq/L by quantitative pilocarpine ionto... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Head and Neck Cancer Histologically confirmed head and neck squamous cell carcinoma (HNSCC), including any of the following subtypes Oropharyngeal Laryngeal Oral Hypopharyngeal No primary nasopharyngeal carcinoma Must have clinical and CT/MRI evidence of nodal metastases staged N2 (a... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 20.0-999.0, Colorectal Cancer Histologically proved adenocarcinoma (colorectal cancer) Age: 20 ≤ at enrollment No prior treatment (ex. radiation therapy, chemotherapy, hormonal therapy) to advanced disease. Patients who received adjuvant chemotherapy more than 180 days before enrollment can be a... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-999.0, Recurrent Thyroid Gland Carcinoma Stage III Thyroid Gland Follicular Carcinoma Stage III Thyroid Gland Papillary Carcinoma Stage IV Thyroid Gland Follicular Carcinoma Stage IV Thyroid Gland Papillary Carcinoma Histopathologically confirmed differentiated thyroid carcinoma of follicul... | 2 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 40.0-999.0, Osteoporosis Men and postmenopausal women who have a previous vertebral osteoporotic fracture that was sustained at least 6 weeks prior to joining the study Patients who are free of severe or chronically disabling conditions other than osteoporosis Patients who are not currently rece... | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-80.0, Diabetes s/p open heart or kidney or liver transplant surgery admission blood glucose less than 120 mg/dl | 0 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 18.0-70.0, Thyroid Cancer Age: 18 to 70 Sonographically node-negative cytology confirmed thyroid papillary carcinoma Tumor size less than 1 cm in sonography Tumor confined to the one lobe of the thyroid gland One who provides the informed consent History of radiation treatment to head and neck ... | 1 |
A 75 yo M w/ metastatic papillary thyroid cancer s/p XRT 19 sessions who presented with 2 days of worsening dysphagia for solids, poor oral intake, weight loss 20 pounds over last several weeks and some lethargy. Papillary thyroid cancer dx w/ right neck mass --s/p neck mass resection; unable to perform thyroidectomy -... | eligible ages (years): 0.0-999.0, Thyroid Neoplasms Carcinoma Thyroid Cancer Metastatic Cancer cytologically or histologically verified anaplastic thyroid cancer completed standard therapy operated with R0 or R1 surgery Performance Status 0-2 (if pulmonary mets PS 0-1) normal wound healing neutrophils > 1,5 million/ml... | 0 |
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