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62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-75.0, Neurosensory Disorder Aged from 18 to 75 years old(including 18 and 75 years old), males or females; 2. First onset, clinical diagnosis of hypertensive intracerebral hemorrhage, and CT confirmed that the amount of hemorrhage is between 15ml-50ml, the bleeding site is the basal ganglia... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Bladder Dysfunction Neurogenic Bladder Dysfunction Urinary Incontinence Urinary Bladder, Overactive Urinary Incontinence, Urge Nocturia Urinary Frequency More Than Once at Night Lower Urinary Tract Symptoms Multiple Sclerosis Urinary Bladder, Neurogenic Self-reported diagnosis of any... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Refractory Non-Hodgkin Lymphoma Burkitt Lymphoma Mantle Cell Lymphoma Follicular Lymphoma Lymphoplasmacytic Lymphoma Primary Mediastinal Large B Cell Lymphoma Diffuse Large B Cell Lymphoma Small Lymphocytic Lymphoma Transformed Lymphoma Patients must have a diagnosis of relapsed or r... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Urethra Stenosis Voluntarily signed written informed consent according to the rules of Good Clinical Practice (Declaration of Helsinki) and national regulations (Appendix B) Age ≥ 18 years Male patient Fit for operation, based on the surgeon's expert opinion Isolated bulbar urethral ... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 15.0-60.0, Urinary Tract Infections Age 15 to 60 years with symptomatic acute urinary tract infection Willing to participate in the study Non-pregnant adult females Clinical signs and symptoms of a UTI (e.g., dysuria, frequency, urgency to urinate, Burning sensations during urination, Hematuria,... | 1 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 0.0-999.0, D007239 Site and Five-hundred patients at each participating site will be enrolled into the trial with a series of and across nine service lines including two surgeons per service line. Site All medical centers with an operating room are eligible. Surgeons performing orthopedic tota... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Diffuse Large B-cell Lymphoma Written informed consent according to ICH GCP E6(R2) regulations before registration and prior to any trial specific procedures Histologically confirmed, treatment-naïve DLBCL, NOS that fulfill all the following Patient eligible for 6 cycles of R-CHOP An... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-75.0, Coronary Artery Disease Intestinal Disease Coronary heart disease verified by coronary angiography Current infection requiring intravenous antibiotics Inflammatory bowel disease Renal failure with creatinine > 200µmol/L Hepatic impairment Pregnancy Previous bariatric surgery Colostom... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 45.0-85.0, Patient Satisfaction Bladder Cancer patients with bladder cancer eligible for surgery Patients who refuse to contribute in this study patients who are unfit for surgery patients refusing cystectomy patients with metastatic or inoperable cancer bladder | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Lymphoma Nonhodgkin Relapsed or Refractory Follicular Lymphoma or Marginal Zone Lymphoma N/A | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-99.0, Urogenital Cancer Cohort-Specific • Bladder cohort: Histopathologically confirmed carcinoma of the urothelium (T1 high grade -T4a) in the bladder with mixed or rare histological subtypes such as squamous cell or adenocarcinoma. Patients with mixed histologies are required to have a do... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Diffuse Large B Cell Lymphoma histologically confirmed diagnosis of CD20+ DLBCL primary central nervous system lymphoma "double-hit" lymphoma | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Non-Invasive Bladder Urothelial Carcinoma Non-Invasive Bladder Papillary Urothelial Carcinoma, Low Grade Non-Invasive Bladder Papillary Urothelial Carcinoma, High Grade Participant has a social security scheme Participant has signed a form of no objection to the use of the data Parti... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Urethral Stricture, Male men with urethral stricture above the age of eighteen were included in our trial. the length of the urethral stricture was less than 1.5 cm patient with complete urethral stricture with a suprapubic catheter in place patients whom internal urethrotomy is not... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Pyelonephritis Acute Suspicion of acute pyelonephritis by ED physician Suspicion of urinary tract infection by ED physician and systemic affection (e.g. fever, sepsis Unable to undergo an MRI Known allergy to US contrast If the attending physician considers that participation will d... | 2 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Acute Pyelonephritis Suspicion of APN assessed by the receiving physician If the attending physician considers that participation will delay a life-saving treatment or patient needs direct transfer to the intensive care unit Admission within the last 14 days Verified COVID-19 diseas... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Urinary Tract Infection Bacterial Adults Diagnosis of UTI defined by at least two of the following symptoms :chills,temperature >38°C (fever), flank or pelvic pain, nausea or vomiting, dysuria, urinary frequency, or urinary urgency, costovertebral angle tenderness on physical examina... | 2 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-80.0, Painful Osteoarthritis of the Knee Participants must understand the nature of the study and must give signed and dated written informed consent prior to the initiation of any study procedures, which includes compliance with the requirements and restrictions listed in the informed cons... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 3.0-14.0, Acute Tonsillitis children from 3 to 14 years old children with sore throat children diagnosed with acute tonsillitis children diagnosed with acute respiratory infection (rhinitis, sinusitis, nasopharyngitis) children with the opportunity to visit the outpatient clinic children with th... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Acute Pyelonephritis Suspicion of APN assessed by the receiving physician at the ED If the attending physician considers that participation will delay a life-saving treatment or patient needs direct transfer to the intensive care unit Admission within the last 14 days Verified COVID... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-80.0, Hemorrhagic Cystitis Males and females, at least 18 years Patients who provided signed written informed consent, which includes compliance with requirements listed in the consent form Patients with diagnosis of Hemorrhagic Cystitis Patients with diagnosis of bladder pain (pressure or ... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Cancer, Lung Perfusion Computed Tomography Target Lesion Cancer Liver Metastatic Lung Cancer Metastatic Liver Cancer Patients suffering from primary malignant thoracic tumoral pathology or second line patients having had a therapy pause of at least 6 weeks; at least one tumoral lesio... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 50.0-85.0, Urinary Tract Infections Female 2. Age 50 3. Have RUTIs (at least 2 UTIs within the past 6 months or 3 within the past year) - Being on antibiotics at baseline (i.e. suppressive therapy or antibiotic therapy for urinary or non-urinary infections) 2. Neurogenic bladder condition 3. Us... | 1 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Kidney Stone Patients with planned PCNL and a preoperative CT scan Urologist obtained access and prone positioning during surgery Tract dilation performed either using balloon dilator or a single step mini-PCNL dilation Age: ≥18 years' old Stone size: 10-25mm Gender: Male and female ... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-100.0, Neurogenic Bladder Post-operative Urinary Tract Infections Participants with neurogenic OAB, defined as OAB associated with a neurologic condition such as multiple sclerosis, Parkinson's disease, spinal cord injury, previous stroke, or any other neurologic condition the participant m... | 2 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 60.0-90.0, Recurrent Urinary Tract Infection Vaginal Atrophy Postmenopausal Disorder 90 yo Female Postmenopausal Recurrent UTIs (three or more culture confirmed symptomatic episodes of UTI or two or more in the past 6 months) English Proficiency Unable or unwilling to use topical estrogen Patien... | 1 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 5.0-18.0, Neurogenic Bladder Neurogenic Bowel Spina Bifida Fecal Incontinence Fecal Impaction Urinary Incontinence Between the ages, 5 to 18, and are diagnosed with neurogenic bladder Use CIC (CIC: Clean Intermittent Catheterization) daily to empty the bladder A recent history of fecal incontine... | 1 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 0.0-999.0, Urinary Tract Infections Nursing Home Inclusion/ Facility is either a SNF, Long term care setting, assisted living Must be certified by Medicare and Medicaid and can either be nonprofit or for-profit freestanding facility Minimum bed size 50 (beds size= staffed beds and not occupied ... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Urinary Tract Infections Inclusion/ Subject is male or female >18 years of age at date of injection Subject receiving BoNT injection for symptoms of OAB (including urgency, urinary incontinence, and detrusor overactivity) refractory to first-line therapies | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Urinary Bladder Neoplasms Patients will be enrolled in this Phase I study only if they meet all of the following Male or non-pregnant, non-breastfeeding female, age 18 years or older at date of consent Any of the following histologically confirmed non-muscle invasive urothelial carci... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-80.0, Intracranial Hemorrhage Patient is between 18 and 80 years of old Patients with ICH rupture into the ventricle in the primary basal ganglia region or non-aneurysmal subarachnoid hemorrhage confirmed by skull imaging examination Patient is admitted to hospital within 72 hours after ons... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 20.0-999.0, Bladder Pain Syndrome Interstitial Cystitis The subject is aged over 20 years old. 2. The subject was diagnosed as bladder pain syndrome/interstitial cystitis subject with lower urinary tract symptoms, such as frequent urination, urgent urination, bladder pain, etc The subject is ag... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-80.0, Urinary Tract Infections Catheter Infection Catheter-Related Infections Infection Patient under age of 80 years old who need prolonged urethral catheterization (more than 2 weeks) as a method of bladder drainage Patients with current or recent symptomatic urinary tract infection Anti... | 1 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-90.0, Recurrent Urinary Tract Infections Diagnosed with recurrent cystitis including 2 times of rUTI within the last 6 months or 3 times in the last 12 months, where at least 2 cultures show the same bacteria Normal investigation for lower urinary tract diseases (LUTD) including voiding dia... | 2 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-999.0, Diffuse Large B-Cell Lymphoma Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma Patients must have histologically confirmed DLBCL, irrespective of cell-of-origin. Patients with previously diagnosed ind... | 0 |
62 yo male with hx of CVA, neurogenic bladder with indwelling suprapubic catheter with multiple prior admissions for UTIs, altered mental status, and urosepsis presents to the hospital in urosepsis now resolved after treatment with vanc/meropenem. Per CT there is a non-obstructing stone in the L ureter, no evidence of ... | eligible ages (years): 18.0-80.0, Bone Metastases From Solid Tumors The subject or his/her guardian and/or impartial witness voluntarily signed the written informed consent form（ICF） Aged 18 to 80 Years old (Female or male subjects to the date of signing the informed consent form) Subjects with solid tumor confirmed b... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Sepsis Respiratory Distress Syndrome Respiratory Distress Syndrome, Adult ENTRY --Disease Characteristics-- Diagnosis of adult respiratory distress syndrome (ARDS) with sepsis ARDS characterized by: hypoxemia refractory to supplemental oxygen therapy, diffuse pulmonary infiltrates, n... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 55.0-999.0, Dementia Alzheimer Disease, Pain Behavior, Agitation Patients must be: 55 years old and older, nursing home residents, a diagnosed painful that would respond to tylenol, documented agitated behavior, a dementia diagnosis or a functional impairment severe enough to rate a 7 on the Glo... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Leukemia B-cell acute lymphoblastic leukemia Disease involving at least 30% of bone marrow or circulating blasts In first relapse with at least 1 of the following high-risk features Age under 1 year at diagnosis Age over 18 years at diagnosis t(9;22) Occurrence of first relapse less t... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Pulmonary Disease, Chronic Obstructive Patients with chronic obstructive pulmonary disease | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Breast Neoplasms Signed consent Diagnosis made by core biopsy or incisional biopsy Histologic confirmation of invasive breast cancer Clinical staging as IIB (cT3N0 only), IIIA (cT3N1 or cT0-3N2), or IIIB (cT4N0-2) ECOG performance 0 or 1 At the time of entry: *Absolute neutrophil cou... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 45.0-999.0, Chronic Obstructive Pulmonary Disease All patients must have a clinical diagnosis of chronic obstructive pulmonary disease according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines Patients must have a cigarette smoking history of more than 10 pack-years P... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Tachycardia, Ventricular Ventricular Fibrillation ICD indications (Class I-II A) according to the guidelines (patient with coronary artery disease [CAD] or non-CAD in primary or secondary ICD prevention) Patients have been implanted with a Medtronic Marquis family ICD capable of ATP ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Tachycardia, Ventricular Ventricular Fibrillation CRT + ICD indications (Class I-IIA) according to the guidelines Patients have been implanted with a Medtronic Marquis Family ICD capable of RV-ATP or BIV-ATP Patients in chronic AF who undergo a complete AV ablation and that the compl... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-60.0, Malaria, Falciparum Ages 18-60 years 2. P. falciparum parasitemia (1,000-100,000 parasites/ul). 3. Clinical syndrome consistent with malaria associated with documented fever (axillary temperature > 38℃) or self-reported history of fever in the last 48 hours with no other cause present... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 14.0-60.0, Schizophrenia Obesity Diagnosis of schizophrenia or schizoaffective disorder Body mass index (BMI) greater than 27 Stable on antipsychotic drug regimen for at least 1 month prior to study entry Parent or guardian willing to provide informed consent, if applicable Positive and negative... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-85.0, Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease Aspirin therapy Cardiac Pacemaker - | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 15.0-999.0, Tuberculosis Adults 18 years of age or older; 2. Have sputum smear positive or sputum smear negative pulmonary or extrapulmonary TB, using the standard NTP definitions for these diagnoses; 3. Have never received more that one month of anti-tuberculosis treatment in the past (that is,... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 55.0-999.0, Heart Failure Chronic Obstructive Lung Disease diagnosis of Chronic Heart Failure diagnosis of Chronic Obstructive Pulmonary Disease living in a nursing home inability to give informed consent involved in other studies of CHF or COPD | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea Gastroesophageal Reflux Adults (> 18 years old) with mild to moderate OSA (as defined by an apnea-hypopnea index between 5 and 30) currently on no therapy. 2. GERD as documented by 24 pH probe (> 6% of the time with pH < 4). 3. Agreeable to participating in th... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-999.0, COPD -History of COPD and cigarette smoking Clinical diagnosis of asthma Chest X-ray that is diagnostic of a significant pulmonary disease other than COPD Disease of other major organ systems | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, COPD Medical diagnosis of COPD Current or prior history of cigarette smoking Medical diagnosis of asthma Chest x-ray (CXR) prior to Day 1 diagnostic of significant disease other than COPD Significant condition or disease other than COPD | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-65.0, Chronic Headache Analgesic Rebound Headache Chronic Daily Headache Headache, Intractable Adult subjects (18-65 years) with CDH by the of Silberstein and Lipton.41 i.e. on the basis of pre-randomization history suffer chronic headaches lasting more than 4 hours a day for more than 15 d... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 65.0-999.0, Respiratory Tract Infection Age 65 years of age and older current season influenza immunization available for follow-up visits willing and able to sign written informed consent HIV infection malignancy (under active observation or treatment) unstable cardiovascular diseases renal ab... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Chronic Obstructive Pulmonary Disease Patients with chronic obstructive pulmonary disease and an acute exacerbation After the acute treatment a simple pulmonary function test shows a value of 30%-60% of the predicted normal value Patients, who, based on the clinical examination after... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-60.0, HIV Associate Weight Loss HIV positive men, 18-60 years of age, with objective evidence of HIV-infection with low to low-normal testosterone levels (<400 ng/dL). In boys before the age of 18, the hormonal and body composition changes of puberty can confound the data. We will men over ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-50.0, Obesity Chronic Sleep Deprivation to 50 year old obese men and premenopausal women BMI between 29-55 Chronically (for more than 6 months) sleep-deprived, defined as sleeping on a regular basis less than or equal to approximately 6-1/2 hours/night by history and objective devices (wris... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea Stroke Ischemic stroke within 7 days of planned polysomnography/sleep screening study Modified Rankin Scale score >1 If of child-bearing potential, has a negative urine or serum pregnancy test Decompensated heart failure Cardiac or respiratory arrest within t... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Chronic Obstructive Pulmonary Disease Patients admitted with will be recruited for the study. will be defined when a patient with background COPD has at least two of the major symptoms (increased dyspnoea, increased sputum purulence, increased sputum amount) or one major and one mino... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-95.0, Obstructive Sleep Apnea Syndrome Glaucoma OSAS planned begin of a nCPAP treatment Current malignancy Oral steroids | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Chronic Obstructive Pulmonary Disease Admission for chronic obstructive pulmonary disease Other severe acute or chronic diseases | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Sleep Apnea Syndrome Obese patient scheduled to undergo bariatric surgery Age less than 18 Active smoking Psychotropic medication Angiotensin-converting enzyme inhibitor or angiotensin II receptor antagonist medication Pregnancy Anesthesia or endotracheal intubation during the previ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Cancer Pregnancy Patients do not need to participate in both; however, preferentially both study parts should be performed. **************Part I: Pregnancy, delivery and maternal health************** Patients must meet the following Histologically proven cancer in association with a ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-80.0, Chronic Obstructive Pulmonary Disease 80 years stable COPD FEV1 < 60 % predicted severe chronic breathlessness (Baseline Dyspnea Index < 6) SpO2 at rest < 90% or a a sustained decrease of > 4% in arterial O2 saturation during the ergometer test, as determined by pulse oximetry a body... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Sleep Apnea Syndromes Inflammation Moderate to severe OSA (as defined by an apnea-hypopnea index [AHI] score greater than 15 events per hour) Body mass index greater than 30 kg/m Baseline CRP greater than 1.0 mg/dL Predominant central sleep apnea Type 1 Diabetes Type 2 Diabetes assoc... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Pulmonary Hypertension Summarized 1. 18 years of age or older 2. Current diagnosis of PH associated with an acceptable etiology as outlined in the protocol, including: PH due to the following etiologies: 1) PAH including idiopathic and familial PAH and PAH associated with collagen va... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Chronic Obstructive Pulmonary Disease Exertional dyspnea Activity limitation COPD Recent exacerbation (< 4 wks) Supplemental O2 Significant cardiovascular/musculoskeletal abnormalities | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-85.0, Sleep Critical Illness Patients requiring mechanical ventilation with a diagnosis of Acute Respiratory Distress Syndrome Cardiogenic Pulmonary Edema Pneumonia Chronic obstructive pulmonary disease Patients who are considered too unstable to undergo this investigation by their primary... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Total Knee Arthroplasty undergoing primary, unilateral knee replacement 2. age 18 years 3. postoperative analgesic plan includes perineural local anesthetic infusion and 4. the availability of a "caretaker" who will remain with the patient from home discharge until catheter removal m... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 2.0-16.0, Obstructive Sleep Apnea Males or females aged 2 to 16 years. 2. OSAS diagnosed on polysomnography. 3. Positive airway pressure therapy indicated by patient's physician because surgery was either contraindicated or ineffective. 4. No plans for upper airway surgery in the next 3 months ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Acromegaly Growth Hormone Deficiency for acromegaly Clinical and biochemical diagnosis of acromegaly. Thyroid and glucocorticoid replacement if necessary stable for at least 4 weeks before the study. Gonadotrophin status will be recorded and whenever possible patients will be studied ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 2.0-10.0, Obstructive Sleep Apnea ages 2-10 ASA rating of I-III undergoing general anesthesia tonsillectomy with and without adenoidectomy diagnosis of anxiety disorder or chronic pain syndrome chronic disabilities or developmental delays are currently on psychotherapeutic or sedating medicatio... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-75.0, Breast Cancer Obesity Weight Changes At increased risk for developing breast cancer due to any of the following lifestyle risk factors Lack of physical activity Excess weight Obesity Weight gain over lifetime Body mass index > 25.0 Physically able to undertake a moderate exercise or c... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-999.0, Osteoporosis Postmenopausal women at or above the age of 50, diagnosed with primary osteoporosis may be enrolled in the trial if the following inclusion/ apply. All must be answered "yes" for a subject to be enrolled in the trial. 1. Has the subject given informed consent according ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Delirium Agitation Ventilator Weaning Respiration, Artificial Intensive Care Patients will be eligible for the study if, in the opinion of the treating clinician, they continue to require mechanical ventilation only because their degree of agitation requires such a high dose of sedat... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Lung Cancer Precancerous Condition Meets 1 of the following Current smoker, defined as ≥ a 20 pack year smoking history and/or 20 year duration of smoking Ex-smoker who has quit smoking within the past 8 years AND has ≥ a 20 pack year smoking history and/or 20 year duration of smoking... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Type 2 Diabetes Mellitus Diagnosed with type 2 diabetes Treated with metformin and/or a thiazolidinedione HbA1c between 6.5% and 9.5%, inclusive Body Mass Index (BMI) > 25 kg/m^2 and < 40 kg/m^2 Have previously received exenatide or glucagon-like peptide-1 analogs Have participated i... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Coronary Artery Disease Obstructive Sleep Apnea Patients with angiographically-verified CAD who have newly undergone PCI or CABG treatment Written, informed study consent OSA (AHI>=15 per hour) or non-OSA (AHI<5 per hour) diagnosis on the unattended sleep recording at home Patients w... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Chronic Obstructive Pulmonary Disease Adult males or females with a diagnosis of COPD screened for nocturnal desaturation as indicated above Clinical stability defined by absence of treatment change or need for acute care within the last two months Weight stable, within 5%, in the pr... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-90.0, COPD All patients admitted to King's College Hospital with a clinical diagnosis of acute exacerbation of COPD. Patients with radiological and microbiological evidence of pneumonia with co-existing COPD will also be included Significant co-morbidity that could limit exercise training ... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 45.0-70.0, COPD Age 45-70 yrs of age, incl, women as described above as far as child-bearing potential and subjects who if they have coexisting disease, the disease is stable and does not place an untoward risk or result in compromise of data Non smokers will be lifelong and have not worked in a... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-90.0, Osteoporosis 18 years old or greater 2. agree to at least one bone biopsy 3. agree to BMD, blood and urine tests 4. receiving at least 10 mg/day of prednisone for at least three months 5. either be a candidate for alendronate or be taking alendronate (70 mg/week for at least three mon... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Restless Legs Syndrome Outpatients with RLS diagnosed by a movement disorder specialist/ Sleep specialist . 2. Patients must report some degree of pain which occurs on a regular basis. 3. Age 18 years to 80 years. 4. Women of child-bearing potential must use a reliable method of contr... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Cardiovascular Diseases Males or females at least 18 years old. 2. Patient has not been previously enrolled in the genebank registry. 3. Patient able to give informed consent. 4. Patient to undergo cardiac catheterization or had a left heart cath at The Cleveland Clinic or at The Uni... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Non-Small Cell Lung Cancer Brain Metastasis Histological or cytological documented stage IV NSCLC. Sputum cytology alone is excluded 2. Extracerebral lesions show stable disease after first line chemotherapy. Patient has recovered from CTCAE grade 3/4 toxicity. Patients who had never... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, COPD Pulmonary Hypertension Diagnosis of COPD Prior admittance to hospital with exacerbation in COPD Informed consent Exacerbation in COPD less than 6 weeks before examination | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 25.0-75.0, Heart Failure previous history of symptomatic heart failure caused by left ventricular systolic dysfunction inspiratory muscle weakness (PImax < 70% of the predicted) clinical stability, including no change in medications for the past three months unstable angina myocardial infarctio... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Central Alveolar Hypoventilation Syndrome Members of familiar congenital central hypoventilation syndrome Refuse to participate study | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-80.0, Lung Diseases, Obstructive Chronic Heart Failure Chronic Hypoxemia Age 40 > 80 years Confirmed COPD (GOLD criteria) Moderate and stable hypoxemia (55< PaO2 <65 mmHg) Clinical signs of CHF (ESC criteria) Ex-smokers (> 20 pack/years) since at least 3 months Clinical instability and/or ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-999.0, Alzheimer's Disease Male or female subjects with a clinical diagnosis of probable Alzheimer's disease The subject has an MMSE score at screening of 12 to 26 for Part A and 16-26 for Part B Age ≥ 50 and above If female, the subject must be post-menopausal (i.e. 12 months without menst... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease Cardiac failure Renal failure Liver failure Diabetes mellitus Systemic inflammatory diseases eg Rheumatoid arthritis, SLE Warfarin, coagulation problems | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 2.0-99.0, WAGR Syndrome Wilm's Tumor Aniridia Urogenital Abnormalities Mental Retardation For WAGR/11p deletion subjects: 1. Diagnosis of WAGR/11p deletion confirmed by prior genetic testing or clinical history consistent with WAGR syndrome (Wilms Tumor and/or genitourinary anomalies plus anirid... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Ventricular Fibrillation Tachycardia, Ventricular Ventricular Flutter ICD Patient Population Indication for 1-/2 chamber ICD implantation, including replacement indication Patient is willing and able to comply with the clinical investigation plan and has provided written informed con... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-90.0, Latent Autoimmune Diabetes in Adults LADA Male, non-fertile female (i.e., post menopausal, post hysterectomy, or sterilized by tubal ligation) or female of childbearing potential using a medically approved birth control method. 2. The patient has a diagnosis of diabetes mellitus accor... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 35.0-999.0, COPD Exacerbation Both inpatients and outpatients with acute COPD exacerbation will be selected for randomization. Patients will be considered to fulfill the diagnosis of if they meet the following 5 1. Patients must have had a previous diagnosis of chronic bronchitis, emphysema or C... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Cramps Amyotrophic Lateral Sclerosis Patients must be at least 18 years of age and have full legal capacity Patients must voluntarily give written informed consent Patients diagnosed with possible, probable laboratory supported, probable or definite ALS according to the revised El Es... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Cachexia Chronic Obstructive Pulmonary Disease Chronic Heart Failure diagnosis of CHF or COPD current body weight less than 6 months ago BMI >=20 and <=30 kg/m2 CHF: LVEF >=45% measured within the past 6 months symptom status equivalent to NYHA class II to IV biochemical abnormalities... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Thyroid Function Obesity Patients who underwent bariatric surgery between 1998 and 2007 age >18 years | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-75.0, Chronic Obstructive Pulmonary Disease COPD patients on necessity of long-term oxygen therapy Patients treated by LTOT, with or without clinically fulfilled for LTOT, with PaO2<55mmHg or less at rest or during sleeping or less during exercise, if supplemental oxygen is demonstrated to ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-999.0, Alzheimer's Disease adult patients, >/=50 years of age probable Alzheimer's disease MMSE score at screening of 13-22 under stable donepezil treatment given at a fixed dose of 5 or 10mg daily for >=4 months prior to baseline not requiring nursing home care, but looked after by a careg... | 0 |
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