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70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, COPD i. Patients with a diagnosis of COPD, emphysema, or chronic bronchitis ii. Age ≥ 40 years-old iii. Smoking history ≥ 10 pack-years iv. Presentation to the emergency room with increased dyspnea, increased sputum, or increased cough v. Admission to the hospital i. Alternative dia... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, ST-elevation Myocardial Infarction (STEMI) ≥ 18 years age Informed (verbal consent) prior to angiography STEMI ≤ 6 hrs of symptom onset, requiring primary reperfusion by PCI Single-vessel coronary artery disease (non culprit disease ≤70% stenosis at angiography) TIMI flow 0/I at angi... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Agitation Excited Delirium Pain Agitation Group Patients with agitation as defined by an Altered Mental Status Score of >1, and who are in restraints or are given sedatives for treatment of agitation. Agitation Group Less than 18 years of age Suspected or confirmed pregnancy Pain Gr... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Obesity Hypoventilation Syndrome Patient with Obesity hypoventilation Syndrome (BMI≥ 30 kg/m2 and diurnal PaCO2 ≥ 45mmHg at diagnosis after of others causes of hypoventilation) to 75 years old In stable state but treated by nocturnal NIPPV for more than 3 months and adherent to NIPPV ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 20.0-85.0, Obesity Hypoventilation Syndrome Man or woman, stable patient with obesity hypoventilation syndrome, naives of non invasive ventilation PaCO2 ≥ 45 mmHg PaO2 < 70 mmHg BMI ≥ 30Kg. m2 Chronic obstructive pulmonary disease Neuromuscular disease Scoliosis Cardiac insufficiency Significan... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Pain Disorder Sensory Deficit Adults ASA physical status I-III BMI<30 No contraindications to study procedures Pediatric patients ASA physical status IV BMI>30 Contraindications to study procedures Hypersensitivity to local anesthetics | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-80.0, Memory Impairment Between the ages of 50 and 80; 2. Having a primary care physician; 3. Ability to speak, read, and write English; 4. Logical Memory subtest (of the Wechsler Memory Scale IV [WMS-IV]) raw score one standard deviation or greater below the mean of a younger population; 5... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Chronic Obstructive Pulmonary Disease (COPD) -Individuals over the age of 18 who have COPD or may be considered to be at increased risk for development of COPD -Individuals under the age of 18 | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Chronic Obstructive Pulmonary Disease patients hospitalized for exacerbation of COPD patients presenting change in mental status (confusion, lethargy or coma) persistence or worsening in hypoxemia (PaO2<40mmHg) and/or respiratory acidosis (pH<7.25) despite oxygen supplementation or u... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-85.0, Ventricular Tachycardia Coronary Artery Disease Sustained monomorphic VT (>30 seconds, or requiring appropriate ICD therapy in patients with ICDs) Documented ischemic heart disease with no further options for revascularization Ability and willingness to give written informed consent t... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-90.0, OSA COPD stable COPD patients cancer exacerbation in recent 2 months pregnancy central type sleep apnea claustrophobia chronic respiratory failure | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Pulmonary Disease, Chronic Obstructive Diagnosis of chronic obstructive pulmonary disease 2. Smoking history of more than 10-pack years History of asthma, allergic rhinitis, myocardial infarction or unstable of life-threatening cardiac arrhythmias 2. Marked baseline prolongation of ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Pulmonary Disease, Chronic Obstructive All patients must sign an informed consent consistent with International Conference on Harmonization Good Clinical Practice (ICH-GCP) guidelines prior to participation in the study and conducting any study procedures. 2. Adult male or female pat... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Hyperglycemia Diabetes Mellitus Admission for Chronic Obstructive Pulmonary Disease (COPD) exacerbation Treatment with pharmacological doses of glucocorticoids (GCs) ≥10 mg of prednisone or its equivalent if they are not on maintenance dose of GCs in the outpatient settings Treatment ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Hypoparathyroidism Primary Hypoparathyroidism low levels of intact PTH during hypocalcemia at diagnosis Subjects receiving calcium and vitamin D supplementation at least 1 year prior to the beginning of the study Subjects able to adhere to the visit schedule and protocol requirements ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-70.0, Sleep Apnea, Obstructive for OSA Patients OSA (elevated AHI) Age range 18-70 years Any known cardiac (apart from treated hypertension), pulmonary (including asthma), renal, neurologic (including epilepsy), neuromuscular, or hepatic disease Susceptible to stomach ulcers Pregnant women... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 13.0-21.0, Obstructive Sleep Apnea Syndrome Polycystic Ovary Syndrome Sleep Apnea Female Ages 13-21 PCOS BMI >95%ile (Obese group) or <85%ile (Lean group) Controls: ages 18-21, regular menses, BMI <85%ile Breastfeeding Pregnant Use of any steroid preparations (including hormonal contraception),... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Fever COPD Obesity Congenital Heart Disease Respiratory Distress Adults with controlled and non-controlled hypertension (hypertension defined as > 130/90 on two separate occasions and history of hypertension) Adults with known chronic obstructive pulmonary disease in respiratory distr... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Snoring every night snoring; 2. no medication known to influence nasal resistance (e.g., antihistamines, vasoconstrictors, topical or systemic steroids); 3. no smoking for the last 6 months; 4. no upper or lower respiratory tract disease (e.g., upper respiratory tract infection, rhini... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Celiac Disease Hypothyroidism Celiac Sprue Malabsorption Patients with the diagnosis of hypothyroidism that require thyroid replacement therapy Surgical resection of thyroid tissue, neck irradiation, radioactive iodine therapy, prior medical treatment with lithium, methimazole, prop... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-50.0, Obesity Morbid Obesity Male and female subjects aged 18 to 50 years at screening who meet the following and will be eligible for enrollment Able to provide written informed consent prior to any study procedures, and be willing and able to comply with study procedures Body mass index ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-90.0, Alzheimer Disease Mild Cognitive Impairment Signed and dated written informed consent obtained from the subject or the subject's legally acceptable representative ( if applicable) in accordance with the local regularities. 2. Both male and female, aged > 50 and <90, if women, must hav... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-999.0, Dementia pertain to both the person with dementia (PwD) and the caregiver (CG) such that if either is eligible but the other is not, the dyad is not enrolled PwD and caregiver are English speaking Diagnosed with probable dementia PwD is able to participate in at least 2 activities of... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 65.0-999.0, COPD Caucasians Age > 65 years Smoking history > 20 pack/years (current or former smokers) Diagnosis of COPD according to GOLD 2010 Stable condition History of bronchial asthma Other chronic diseases such as interstitial lung disease, bronchiectasis, bronchiolitis obliterans organiz... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obesity Hypoventilation Syndrome years old ans more BMI over 30 kg/M2 Stable state (respiratory, metabolic and cardio-vascular) for the last 2 months Addressed to a clinical labs for a blood check-up whatever the prescription No social security Non cooperative patient, as judged by ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Chronic Low Back Pain Patients with disc herniation or radiculitis who are over 18 years of age. 2. Patients with a history of chronic function-limiting low back pain and lower extremity pain for at least one months' duration. 3. Patients who are competent to understand the study and... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea Obesity Obstructive Sleep Apnea Obesity BMI>30 Controlled on Continuous Positive Airway Pressure for three months cardiac co-morbidity e.g ischaemic heart disease, chronic heart failure, valvular heart disease pulmonary co-morbidity neurological condition lim... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-65.0, Sleep Apnea Syndromes clinical diagnosis of obstructive sleep apnea (OSA) and excessive daytime sleepiness (EDS) body mass index of at least 25 kg/m^2 prior treatment with CPAP shift workers type 2 diabetes poorly controlled severe hypertension anemia history of coronary artery disea... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 35.0-80.0, COPD Stable COPD without an exacerbation within 3 months prior to study entry mild, moderate and severe COPD with or without treatments, regardless of COPD medications Concomitant other chronic lung diseases including with TB and malignancy HIV Being on immunosuppressive drugs and sy... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-70.0, Hypoxia Subjects must be healthy, well trained and have basic mountaineering experience Written informed consent Subjects with any type of cardiac and or respiratory disease Subjects with diabetes mellitus type I or II Regular intake of beta-blockers, ACE-inhibitors, nitrates and cal... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, COPD Male or female aged ≥40 years at screening 2. History of COPD for at least 18 months prior to screening, characterised by excessive sputum production 3. Chronic productive cough for at least 3 months in each of the 2 years prior to screening (if other causes of productive cough ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Coronary Artery Disease Endothelial Function Age above 18-80 years old 2. Patients with Coronary Artery Disease receiving ticagrelor maintenance dose (MD) 90mg x 2 and are about to discontinue the treatment due to the completion of 1 year of dual antiplatelet therapy. 3. Patients givi... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-999.0, Obesity Hypoventilation Syndrome Greater than or equal to 21 yrs. of age Referred to sleep lab for diagnostic PSG, initial titration PSG or split night PSG as routine clinical care BMI greater than or equal to 30kg/m2 Acutely ill or medically unstable to participate per PI Current p... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 19.0-999.0, Chronic Pain Pain Widespread Chronic Pain Chronic Pain Syndrome Chronic Pain Due to Injury Must be at least 19 yrs-old in order to consent to treatment. 2. Must have received at least one diagnosis consistent with chronic pain by a physician at one of the participating primary care c... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-80.0, COPD Primary diagnosis of defined as acute increase in dyspnea, sputum volume, and/or sputum purulence without other identified cause; admission to the hospital <12 hours; patient age >40, < 80 years old; cigarette smoking > 10 pack-years; informed written consent Prior diagnosis or ... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Pulmonary Disease, Chronic Obstructive (COPD) COPD patients Exacerbation in the last 4 weeks | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-65.0, Adult Lymphoblastic Lymphoma Disease ALL in complete remission (CR) at the time of transplant. Remission is defined as "less than 5.0% bone marrow lymphoblasts by morphology," as determined by a bone marrow aspirate obtained within 2 weeks of study registration Philadelphia chromosome... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Breast Cancer Nos Metastatic Recurrent Women Aged 18 years and over With an invasive breast cancer diagnosed by cytology or histology Tumors cT0 to cT3, CN0-3 No clinical evidence of metastasis at the time of Untreated including scored for breast cancer surgery in progress Patient re... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Thyroid Cancer Newly diagnosed with a first occurrence of thyroid cancer <2-4 weeks of diagnosis (i.e., histologically confirmed thyroid cancer (papillary, follicular, or medullary type; TNM classification system) Willing to participate in the EG meetings >18 years Alert and capable ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-65.0, Chronic Pain Women Clinical diagnosis of chronic pelvic pain More than eighteen years Non-menstrual or noncyclic pelvic pain Duration of pain of at least 6 months Duration of pain less than 6 months Women who were pregnant in the last 12 months | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Coronary Artery Stenosis Age ≥ 18 years Patient with an indication for PCI including angina (stable or unstable), silent ischemia (in absence of symptoms a visually estimated target lesion diameter stenosis of ≥70%, a positive non-invasive stress test, or FFR ≤0.80 must be present), ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Chronic Obstructive Pulmonary Disease (COPD) COPD defined as FEV1 (Forced expiratory volume in 1 second)/FVC (Forced vital capacity) <0.70 or chest CT evidence of emphysema 2. Age > 40 years 3. Any severity of COPD as defined by GOLD (Global Obstructive Lung Disease) stages 1, 2,3, o... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Blood Pressure Depression Panic Attack Fibromyalgia POTS Inappropriate Sinus Tachycardia Coronary Heart Disease Acute Coronary Syndrome (ACS) Acute Myocardial Infarction (AMI) Cerebrovascular Disease (CVD) Transient Ischemic Attack (TIA) Atrial Fibrillation Diabetes Mellitus Cancer Sy... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 25.0-70.0, Cardiovascular Disease Subclinical Hypothyroid Patients with subclinical hypothyroidism (otherwise healthy volunteers) Adults aged 25 yrs Willing to avoid consumption of soy/other isoflavone containing foods (i.e. some snack bars) during the study Willing to avoid consumption of dieta... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Chronic Obstructive Pulmonary Disease Patients Hospitalized for a COPD Exacerbation Patients hospitalized for a COPD exacerbation COPD previously diagnosed Allergy to iodinated contrast Creatinine clearance < 30 mL / min Patient hospitalized for exacerbation of COPD for more than 48... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 20.0-999.0, Sleep Apnea, Obstructive all participants needing age > 20 y/o Index proband: OSA diagnosed by overnight polysomnography (AHI>30 or AHI>15 needing therapeutic intervention) Index family: first-degree, second-degree relatives, or spouse of index proband Control proband: friends recomm... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 19.0-95.0, Chronic Obstructive Pulmonary Disease years of age or older diagnosis of COPD patients admitted to the hospital for a COPD exacerbation OR attending the COPD clinic and not experiencing a COPD exacerbation under 19 years of age patients seen in the COPD clinic who are experiencing an... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Sleep Apnea, Obstructive Adults patients (> 18 years) None | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Cholecystitis Cholelithiasis Obstructive Sleep Apnea Obesity (BMI greater than or equal to 30) Symptoms of obstructive sleep apnea as determined by an OSA questionnaire patients will complete preoperatively Prior diagnosis of obstructive sleep apnea Undergoing laparoscopic cholecyste... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Hypoxia Sleep Apnea Obstructive Sleep Apnea Healthy subject Subject aged of 18 years-old at least Diagnostic AHI<15/h and <5% of total sleep time spent with a SaO2<90% Free and informed consent signed Subject covered by social security Negative pregnancy test Subject with a medical ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Chronic Obstructive Pulmonary Disease COPD Exacerbation Tiffenau (FEV17FVC) < 70 without reversibility (Increase in FEV1 after inhalation of a bronchodilator <200 ml and <12%) Age: > 40 years Both genders Smokers or ex-smokers of at least 20 pack years Informed consent < 40 Years Ti... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-80.0, Pulmonary Disease, Chronic Obstructive aged 40-80 years had been diagnosed with COPD following the GOLD were receiving oxygen therapy using a fixed oxygenation system and a portable system for ambulation without exacerbation during the previous month agreed to participate terminally ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Granulomatous Disease, Chronic Participant (Part 1 Longitudinal Analysis) CGD Patients Undergoing Transplant 1995 to Present with Birth Year In or After 1988 1. CGD Patients will be Defined by both Defective Neutrophil NADPH Oxidase Function and by Clinical History Consistent with CGD... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Ventricular Tachycardia Patients with indication for ventricular tachycardia substrate ablation Pregnant woman Reduced expectancy of life (less than 12 months) Patient participating in another clinical study that investigates a drug or device Psychologically unstable patient or deni... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Trachebronchomalacia (TBM) Hyper Dynamic Airway Collapse (HDAC) Obstructive Sleep Apnea (OSA) Females and males ages 18-80 years old Able and willing to provide written informed consent Existing diagnosis of TBM or HDAC or both No pre-existing diagnosis of OSA No history of reconstruc... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 6.0-70.0, Neuromuscular Diseases neuromuscular disorder age greater than or equal to 6 Hospitalization in Home Ventilation Unit Written informed consent patient's refusal to participate major swallowing disfunction Acute respiratory failure no affiliation to social security | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Chronic Obstructive Pulmonary Disease (COPD) Age 18 years or older. 2. Physician diagnosis of COPD 3. Physician prescription for home O2 for 24hrs/day, 7 days/week 4. Willing to use home O2. 5. Working telephone number Unable to read and speak English. 2. Discharge to home hospice o... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 20.0-95.0, Chronic Obstructive Pulmonary Disease Hypoxia Chronic obstructive pulmonary disease No exacerbation No active heart disease | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Critically Ill Obstructive Sleep Apnea Patients admitted to the SICU 2. Age over 18 years. 3. Ventilated patients with an endotracheal tube for at least 24 hours Decreased level of consciousness as defined by a Richmond Agitation Sedation Scale (RASS) of 0. 2. Non-cooperative patien... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 60.0-999.0, Mild Cognitive Impairment aged 60 years or older fluent in Portuguese free of any other significant neurologic or psychiatric diseases | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Chronic Obstructive Pulmonary Disease (COPD) clinical diagnosis of COPD according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) ≥ 18 years old clinical stability for 1 month prior to the study (no hospital admissions or exacerbations) able to provide their own ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea Syndrome Adults 18 or older with obstructive sleep apnea syndrome (OSAS) presenting for CPAP titration Professional singers Television or Radio hosts Disk Jockeys Subjects requiring oxygen therapy Subjects younger than 18 year old Pregnant women Patients with... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 55.0-85.0, Alzheimer's Disease NIA-Alzheimer's Association core clinical for probable AD 2. 18F-Florbetapir scan with evidence of elevated Aβ (based on central review) 3. Age between 55-85 (inclusive) 4. MMSE score between 18 and 26 (inclusive) 5. Stability of permitted medications for 4 weeks. ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Pulmonary Disease, Chronic Obstructive All patients were required to have a diagnosis of COPD and to meet the following spirometric Relatively stable, moderate to severe airway obstruction with an FEV1 ≤ 65% of predicted normal and FEV1/FVC ≤ 70% Patients were required to have normal ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Knee Osteoarthritis Early osteoarthritis as per Brandt grades, persistent joint pain warranting a clinic visit, no previous injections given, significant pain in visual analog scale, failure of exercise and oral analgesics advanced knee osteoarthritis, patients with bloody effusions... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Subclinical hypothyroïdism over 18 years chronic kidney disease subclinical hypothyroidism non-inclusion insulin-dependent diabetes dialysis | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Atrial Fibrillation years or older This cardiac operation is the subject's first or primary cardiac operation The subject must be undergoing an isolated CABG procedure using a median sternotomy approach Must have ability to provide written informed consent Must have ability to fulfil... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Agitation older than 18 years admission in ICU >24 hours amputation paraplegia non french speaking consent refusal | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 2.0-16.0, Obstructive Sleep Apnea children 2-16 years of age scheduled for polysomnogram cardiovascular, neuromuscular, immunologic or craniofacial disorders pharmacologic treatment including corticosteroids and leukotriene receptor antagonists in the last month subjects who have already receiv... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-100.0, Obstructive Sleep Apnea (OSA) Aged 18+ Diagnosed with OSA by a practicing sleep physician Patients with a known history of Cerebrospinal fluid leak, abnormalities of the cribriform plate, head trauma and/or pneumocephalus Patients with pathologically low blood pressure, pneumothorax... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 19.0-75.0, Obstructive Sleep Apnea You may be able to participate in this study if You are naïve to treatment (never used CPAP or oral appliance, nor had surgery for sleep apnea) You are between 19-75 years old You have a Body Mass Index (BMI) ≤ 35 You have enough teeth (at least 8 per arch) for... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Obstructive Sleep Apnea Chronic Obstructive Pulmonary Disease Overlap Syndrome Both men and women with age more than 18 years Known diagnosis of stable COPD (GOLD stage 2 or higher) or OSA Already using continuous positive airway pressure (CPAP), BPAP device, or nocturnal oxygen Know... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Cystic Fibrosis Male or female, age ≥ 18 years with confirmed diagnosis of CF, homozygous for the F508del-CFTR mutation based on historical results generated by Ambry Genetics within the past two years or if unavailable, confirmed by testing done within the past 28 days 2. Sweat chlor... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea Clinical suspicion of obstructive sleep apnea (OSA) Appropriate for home sleep testing No prior use of CPAP or other therapies for OSA Commercial drivers Complex sleep disorders (e.g. CSA) No DME (durable medical equipment) insurance coverage Declines CPAP th... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-70.0, Chronic Obstructive Pulmonary Disease (COPD) Patients from Zhu jiang Hospital,Southern Medical University Patients aged 40-70 years old Patients with pulmonary function test of forced expiratory volume at one second (FEV1)/forced vital capacity(FVC) < 70% and 30% ≤ FEV1%pred < 80% Pat... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Female Infertility Due to Diminished Ovarian Reserve Menopausal Syndrome Sexual Function and Fertility Disorders Cardiovascular Diseases Karnofsky Performance Statue ≥ 70 WBC > 3,000/mm³ Hb > 9.0g/dl Platelet > 100,000 /mm³ SGOT/SGPT < 60 IU/L T-Bil < 1.5 mg/dL Cr < 1.2 mg/dL PaO2 > 8... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-85.0, Ventricular Tachycardia ≥ 18 and ≤ 85 years of age History of a remote MI (≥1 month) Survival of a ventricular arrhythmic event (VT/VF) that would mandate placement of an implantable cardioverter-defibrillator (ICD) (Patients who experience a ventricular arrhythmic event (VT/VF) while... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Cardiac Surgery Every patient of more than 18 years, programmed for a cardiac surgery ( valve replacement, coronary bypass, aortic surgery) in the service of "Chirurgie Cardio-Thoracique et Vasculaire" (CCTV) of the CHRU of Brest and obesity (BMI > 30 kg/m2 and/or COPD (stages 1-2 an... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Respiratory Insufficiency Obesity Hypoventilation Syndrome Chronic Obstructive Pulmonary Disease (COPD) Neuromuscular Disease Upper Airway Obstruction Patient has COPD, Obesity Hypoventilation Syndrome or Neuromuscular disease with hypercapnia Clinically established on bilevel therapy... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Colorectal Cancer Patients scheduled for elective colorectal surgery With one of these following conditions: ≥ 70 year old; Respiratory co-morbidity defined as: obstructive pulmonary disease diagnosed by abnormal spirometry test, alveolar-arterial oxygen differences >15 mmHg, Sleep a... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Chronic Obstructive Pulmonary Disease Age >40 years Clinically diagnosed as COPD by physicians Obtain any one of exacerbating symptoms (increased dyspnoea, sputum production, sputum volume, wheeze, cough or exertional dyspnoea) Known or suspected pregnancy, lactating patients, activ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Atrial Fibrillation ≥ 18 years of age Patients of African, European, and Hispanic descent History of typical or early-onset symptomatic (≥2 episodes/month) paroxysmal/persistent AF ECG that was recorded within 1 month of randomization showing AF Eligible for both Flecainide(Class I) ... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 22.0-999.0, Apnea, Sleep Adults (≥ 22 years) Self-report of daytime somnolence Body mass index (BMI) ≤ 32 Mild to moderate obstructive sleep apnea (AHI 10 lowest O2 sat ≥ 80%) Evidence of palate and tongue base collapse on supine fiberoptic examination Non-compliant with or refusal of continuous... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 55.0-999.0, Alzheimer Disease Agitation Weight Loss Pain Oxidative Stress Males or females ≥55 years of age Diagnostic and Statistical Manual (DSM) -V for Major Neurocognitive Disorder due to AD. Patients with both Major Neurocognitive Disorder due to AD and Major Vascular Neurocognitive Disorde... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Neuromuscular Disease Neuromuscular disease Age ≥18 years Non mechanically ventilated Long-term oxygen therapy | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Overlap Syndrome Major patients, of less than 80 years Patients with chronic respiratory failure within a Overlap syndrome ( defined by the coexistence of COPD and OAS ) in stable situation (no exacerbation for at least 4 weeks) , indication for a NIV treatment OAS confirmed by polyso... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 22.0-999.0, Snoring Obstructive Sleep Apnea Age ≥ 22 years (no upper limit) Regular bed-partner Chronic, disruptive snoring according to bed-partner Snoring, upper airway resistance syndrome, or mild obstructive sleep apnea (AHI ≤ 15; lowest O2 saturation ≥ 85%) on home sleep testing with Watch-... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Sleep Apnea, Obstructive Obesity Hypoventilation Syndrome Aged 18+ Patients diagnosed with obesity hypoventilation syndrome (OHS) and/or obstructive sleep apnea (OSA) by a practicing sleep or respiratory physician, requiring positive airway pressure (PAP) therapy Recent cardiac or r... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Central Sleep Apnea, Secondary Opium or opioid use for at least two months in a daily manner Presence of five or more central sleep apnea per hour in a full-night recorded PSG Congestive heart failure living in high altitude Chronic Obstructive Pulmonary Disease (COPD) Carbon dioxid... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, COPD Exacerbation COPD patients suffering from acute hypercapnic respiratory failure (PaCO2 > 50 mmHg) due to COPD exacerbation and requiring intermittent NIV treatment can be included in the study provided they do not require immediate intubation Patients younger than 18 years old ... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Chronic Asthma COPD and outpatients older than 18 years, who have a clinical diagnosis of asthma or COPD At least one exacerbation in the last year Participants need to be able to give informed consent A good knowledge of the German language by themselves Patients with a metered dose... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 10.0-18.0, Obesity Obstructive Sleep Apnea Sleep Disorders Cardiovascular Disease Obesity, BMI > 95th centile for age and gender 18 years of age Informed consent and the ability to perform the tests Moderate to sever OSAS (will be eligible for in the treatment group for this study) Use of anti-... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Ventricular Tachycardia Patients with VT and have an implanted ICD who are scheduled for VT catheter ablation Patients 18 years of age or older Patients with difficult airway management or patients with contra/ relative contra indication for general anesthesia or known allergies to ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-76.0, Sleep Apnea, Obstructive Renal Insufficiency, Chronic CKD stage 3 or 4 OSA (RDI>5) and nocturnal hypoxemia (SaO2 <90% for >12% of night) Failure to meet Current therapy with CPAP or supplemental oxygen Severe daytime sleepiness reflected by an Epworth Sleepiness Score >15 Any driver ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Osteoporosis Diabetes Mellitus Males or females ≥ 40 years of age at Visit 1and females in postmenopause for one year Documentation of type 2 diabetes mellitus as evidenced by one or more of the following 1. With typical symptoms and random blood sugar ≥ 200 mg/dl 2. 8-hour fasting b... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 1.0-22.0, ROHHAD Syndrome Diagnosis of syndrome confirmed by two physicians Any symptomatic improvement in response to a course of rituximab (five weekly doses) as assessed by parents and/or treating physician Normal brain MRI Cared for at home by the family Patients requiring bilevel positive a... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-90.0, Agitation in Patients With Dementia of the Alzheimer's Type Participant has successfully completed Studies 15-AVP-786-301, 15-AVP-786-302, 12-AVR-131, or 17-AVP-786-305 Participants from Study 12-AVR-131 with a diagnosis of probable AD according to the 2011 National Institute on Aging... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Breathing-Related Sleep Disorder Hospitalized patients who are at high risk for readmission who are at least 18 years of age. 2. Specifically patients with (a) admission diagnosis of COPD AND (b) either a prior non-elective hospitalization (One in the past 12 months) OR active smoker... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Arthroplasty, Replacement, Knee Pain, Postoperative The subject is scheduled for elective unilateral TKA 2. The subject is ≥ 18 years and ≤ 80 years; 3. The subject's weight is between 70-120 kg; and 4. The subject's primary anesthesia care team has planned for a neuraxial anesthetic ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-75.0, Sleep Apnea Diabetes Type 2 diabetics Age > 21 and ≤ 75 years Inability to consent or commit to the required visits Use of insulin or other injections for diabetes Weight change of 10% in last six months Use of oral steroids in the last six months Pulmonary disease (i.e., COPD) Renal... | 1 |
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