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70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 6.0-999.0, Attention-Deficit/Hyperactivity Disorder Patients will be male or female outpatients who are at least 6 years of age (there is no upper age limit) 2. Patients must meet DSM-IV for ADHD 3. Patients and parents/guardians must have a degree of understanding sufficient to be able to commu... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Pulmonary Disease Chronic Obstructive Hypercapnia Hypoxemia Arrhythmias, Cardiac COPD (FEV1 < 80 % of pred. and FEV1/FVC < 0,7) other serious disease (like lung cancer, sarcoidosis, restrictive lung disease) exacerbation of COPD within 3 weeks before coronary heart disease with unsta... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Acute Cardiogenic Pulmonary Edema CPE confirmed radiologically and/or clinically 2. Severe acute respiratory failure (partial arterial oxygen (PaO2)/Fraction of inspired oxygen (FIO2) less than 250) 3. Dyspnea of sudden onset with respiratory 4. Systolic blood pressure < 180 mmHg Im... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Nausea and Vomiting Pain Sleep Disorders Unspecified Adult Solid Tumor, Protocol Specific Patients diagnosed with cancer and experiencing chronic neuropathic pain syndrome Pain syndrome diagnosed by the investigator Pain syndrome related to the effects of cancer or its treatment (i.e... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Advanced Cancer Cachexia Age: Patients must be older than 18 years of age Tumour situation: Patients with any type of advanced (defined as locally recurrent or metastatic), incurable solid tumour Cachexia: defined as involuntary loss of weight of ≥2% in 2 months or ≥5% in 6 months, a... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Sleep Apnea Syndrome Suspected sleep apnea syndrome > 18 yr Outpatient Able and willing to use the necessary equipment for registration of nasal pressure and O2 saturation at home hospitalized patients < 18 yr Not able to use the necessary equipment | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Obesity Hypoventilation Syndrome Obesity degree I-III (Body mass index, BMI >30 Kg/m2) Stable daytime PCO2 >45 mmHg Age < 75 years Absence of other parenchymal, respiratory or neuromuscular diseases, diseases of the chest wall which may occur concomitantly with hypoventilation Absence... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-70.0, Obstructive Sleep Apnea Acute Kidney Failure Chronic Kidney Disease Males with high risk of obstructive sleep apnea syndrome as clinically assessed by coincidence of typical symptoms (e.g. daily somnolence, witnessed apnea, non-refreshing sleep), obesity and high score on Epworth slee... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 60.0-85.0, Alzheimer´s Disease Men and women (non-childbearing potential) with a diagnosis of probable Alzheimer's disease according to the clinical criteria. 2. Age 60 years (patients over 85 years could be included after a previous assessment by the investigator and in agreement with the spons... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-85.0, Subclinical Hypothyroidism Subjects with subclinical hypothyroidism Patients taking L-thyroxin therapy Patients with known cardiovascular, cerebral or peripheral atherosclerotic disease | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-89.0, Obstructive Sleep Apnea OSA, Apnea-hypopnea index > 5/hour Prior CPAP Uncontrolled Depression Moderate to Severe chronic obstructive pulmonary disease (COPD) Hypoventilation Average estimated nightly total sleep time < 4 hours Shift work Unstable depression Upper airway surgery Uncon... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Chronic Obstructive Pulmonary Disease Patients with COPD Acute hypercapnic exacerbation of COPD at least 2 weeks previously Tolerated non-invasive ventilation during acute hypercapnic exacerbation Chronic hypoxia requiring LTOT (PaO2 <7.3kPa or a PaO2 >7.3 and <8.0kPa and one of the ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Cancer Survivor Fatigue Psychosocial Effects of Cancer and Its Treatment Sleep Disorders Prior diagnosis of cancer At least 2 months and ≤ 24 months since completed curative-intent treatment (chemotherapy, surgery, and/or radiotherapy) Ongoing hormonal therapy (i.e., tamoxifen, aroma... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, COPD Chest Wall Disease Neuromuscular Disease Obesity Hypoventilation Patients with chest wall deformity, neuromuscular disease or obesity hypoventilation syndrome with an FEV1/FVC ratio of >70% and VC <50% predicted or patients with COPD with a FEV1/FVC ratio of <70% an FEV1 <50% pr... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-90.0, Stroke Impaired Upper Extremity Function An ischemic or hemorrhagic stroke more than 6 months prior to entry into the study trace ability to move the wrist and fingers in extension voluntary shoulder elevation to approximately 45 deg be between the ages of 21 and 90 Have cognitive de... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Obstructive Sleep Apnea Patients with high probability of OSA, defined by two or more of daytime sleepiness snoring recognized apnoeic episodes associating obesity and / or hypertension Patients with impaired lung function ( overlap syndrome, obesity-hypoventilation syndrome, restri... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-70.0, Blood Pressure Platelet Function Inflammation mild hypertension (systolic blood pressure 130-159 mmHg, diastolic blood pressure 85-99 mmHg) smoking regular use of medications (except hormone replacement therapy) or dietary supplements intestinal disorders obesity (BMI> 35 kg/m2) vege... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-55.0, Musculoskeletal Pain Signed and dated informed consent prior to participation Subjects in good health as determined by the Investigator Age 18-55 Willing to abstain from any physical therapy, hard physical work, exercise or sauna during the study observation period (Screening to Final... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, HIV Infection Liver Failure Evidence of Liver Transplantation Age ≥ 18 Documented HIV-1 infection, hepatitis B or C co-infection is allowed Plasma viral load at screening visit below 50 copies per mL for at least 6 months Patient with severe liver failure (Meld Score ≥ 15 and/or refr... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.5-999.0, HIV Infection Rheumatic Disease Cancer Transplant Pediatrics medically recommended influenza A(H1N1) immunization signed informed consent failure or refusal to provide sufficient blood for antibody determination | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-80.0, Chronic Obstructive Pulmonary Disease Obstructive Sleep Apnea Syndrome Presence of Chronic Obstructive Pulmonary Disease stage II and III of Global Initiative for Chronic Obstructive Lung Disease, stable for three months, and with symptoms suggestive of Obstructive Sleep Apnea Syndrom... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-59.0, First Episode Psychosis Aged 18-59 years and meet DSM-IV diagnostic for first episode of schizophrenia, schizophreniform disorder, schizoaffective disorder or psychotic disorder NOS as assessed by using the Structured Clinical Interview for DSM-IV, research version Meeting DSM-IV for... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-65.0, Metabolic Syndrome Insulin Resistance Adipokines Cytokines for part A: Patients who are included in the obesity surgery program will be recruited if they fulfill the following Age between 18 and 65 years Body mass index (BMI) >40 kg/m2 or BMI > 35 kg/m2 with co-morbidity related to ob... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Metastatic Melanoma ENTRY Locally advanced or metastatic melanoma Measurable Histologically or cytologically confirmed Surgically incurable HLA-A2 positive and tumors that present HLA-A2.1/p53aa264-272 complexes PRIOR/CONCURRENT If prior Proleukin treatment, must have had clinical be... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea Chronic Obstructive Pulmonary Disease Obstructive sleep apnea (OSA) COPD Inability to perform exercise test due to musculoskeletal limitation Cardiac condition preventing patient from mild exercise Continuous oxygen supplement | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Chronic Obstructive Pulmonary Disease Nocturnal Desaturation Patients with a diagnosis of COPD supported by a history of past smoking and obstructive disease: FEV1<70% predicted, FEV1/FVC<70% and a total lung capacity by body plethysmography >80% predicted Stable COPD at study entry,... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 19.0-100.0, Cardiovascular Risk Factors Age ≥ 65 years 2. Hypertension (HTN) 3. Diabetes 4. Obesity (body mass index [BMI] >35) 5. Renal insufficiency 6. Tobacco usage 7. Hypercholesterolemia 8. Sleep apnea/heavy snoring at night 9. Clinical diagnosis of CHF as defined by: 1. Dyspnea on exertion... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-65.0, Obstructive Sleep Apnea Adults, age 18-65 Recently diagnosed with obstructive sleep apnea, confirmed by polysomnography (sleep study) Experiencing daytime sleepiness, based on Epworth Sleepiness Scale Scheduled for a positive airway pressure (PAP) titration study (CPAP or BiPAP) Willi... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Chronic Obstructive Pulmonary Disease A current clinical diagnosis of Chronic Obstructive Pulmonary Disease Documented Chronic Obstructive Pulmonary Disease symptoms for more than 2 years A smoking history of at least 10 pack years History and/or current clinical diagnosis of asthma... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 20.0-75.0, Obesity Hypoventilation Syndrome Patients from 20 to 75 years old Body mass index > 32 kg/m2 Nocturnal oxygen desaturation 5 mn ≤ 88% under CPAP PaCO2 > 5,9 kPa in diurnal, spontaneous ventilation Patients with COPD and VEMS/FVC < 65% Patients with CHF and periodic breathing (Ejectio... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-90.0, Chronic Obstructive Pulmonary Disease Patients who are admitted to the Prince of Wales Hospital with will be screened for this study Patients with age over 40 years Patients with asthma Patients unable to provide informed consent | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-95.0, COPD Heart Failure, Congestive Caucasians Males and females Age > 50 years Smoking history > 10 pack years Diagnosis of COPD according to GOLD 2008 and/or diagnosis of CHF according to ESC 2008 History of bronchial asthma Fixed airflow limitation due to other chronic diseases such as... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Sleep Apnea Adult with healthy mind, who has attained his majority, and affiliated to Social Security Patient suffering from SAS confirmed by polysomnography (PSG) Written informed consent form signed Patients receiving neuroleptics or benzodiazepines and affiliated drugs will not b... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 25.0-90.0, Chronic Obstructive Pulmonary Disease Patient with COPD and increased SPAP >55 on echocardiogram will be screened for the study. 2. Patients with normal wedge pressure ( [PCWP] ≤ 15 mm Hg), mean PAP ≥ 35 mm Hg and a pulmonary vascular resistance (PVR 0 wood unit)on right heart cathete... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-80.0, Chronic Obstructive Pulmonary Disease Elderly patients < 80 years old COPD (ERS/ATS (FEV1 < 80%, FEV1/FVC < 70%, TLC > 80%)) Oxygen therapy indication (PaO2 < 55 mmHg or 55-59 associated to pulmonary arterial hypertension, chronic Cor Pulmonale, Chronic Heart failure, arrhythmias or po... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Neoplasms Any solid tumor malignancies of any stage meeting all of the following Minimum tumor dimension is at least 1 cm (to ensure it is above the detection threshold of PET imaging). Examples but are not limited to: locally advanced squamous cell carcinoma of the head and neck to ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Renal Function HIV Infection > 18 years old. 2. HIV RNA < 50 copies/ml (For ART-experienced group only) a history of Tc-99m DTPA allergy, 2. malnutrition (BMI <18m2), 3. amputation, 4. bed-ridden, 5. currently taking cotrimoxazole or cimetidine, 6. acute deterioration of renal funct... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-85.0, Sleep Apnea Obstructive Sleep Apnea (defined by Apnea-hypopnea index [AHI] > 5 per hour; with hypopneas defined as greater than 30% reduction in airflow with 4 or greater drop in oxygen saturation). AHI will be determined by full night or split-night polysomnography. 2. Age range 21 y... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-65.0, Obstructive Sleep Apnea Insulin Resistance Metabolic Syndrome Inflammation Subjects between 18 years old Able to understand and give informed written consent BMI > 35 kg/m2, and features of obesity hypoventilation syndrome known diabetes mellitus or hyperlipidemia on treatment known ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-80.0, Sleep Apnea Central Cheyne-Stokes Respiration Obstructive Sleep Apnea Males and females, ages 21-80 Able and willing to provide written informed consent Diagnosis of complex sleep apnea (CompSAS) or Obstructive Sleep Apnea (OSA) within one year of study participation For participants ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 1.0-30.0, Acute Lymphoblastic Leukemia Adult B Lymphoblastic Lymphoma Ann Arbor Stage I B Lymphoblastic Lymphoma Ann Arbor Stage II B Lymphoblastic Lymphoma Childhood B Acute Lymphoblastic Leukemia Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 Childhood B Lymphobla... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-69.0, Decrease of Inflammation of Adipose Tissue Sleep Apnea Syndrome Male between 18 and 70 years old Apnea Hypopnea Index > 30/h and > 5% TST with SaO2 < 90% patients obese (BMI > 33kg/m2) or non obese (BMI < 27kg/m2) Female coronary ischemic disease, past history of CVA chronic pulmonar... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-40.0, Pro-inflammatory Activity Immunologic Activity Alteration male and non-pregnant female, non-smoking adults in good general health between the ages of 21-40 years old fluent in English with willingness to participate in the research study Supplementary Prescription Opioid Abusers DSM-I... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-80.0, Chronic Obstructive Pulmonary Disease (COPD) Patient diagnosed with chronic obstructive pulmonary disease (COPD) 2. Age < or = to 80 years 3. Forced expiratory volume in one second (FEV1) < 50% of predicted value 4. FEV1/Forced vital capacity (FVC) < 70% of predicted value 5. Total lun... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Sleep Apnea Syndromes Diagnosed with Moderate to Severe Sleep Apnea Live in San Diego County Veteran Previous use of positive pressure airway therapy Residence outside of San Diego county | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Chronic Obstructive Airway Disease Both men and women with age more than 18 years Known diagnosis of COPD (GOLD stage 2 or higher) Already using CPAP or BPAP device Estimated GFR <30 ml/min/1.73 m2 or on hemodialysis Women known to be pregnant or planning to be pregnant in next 6 mon... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 55.0-999.0, Dementia Alzheimer's Type Patients with diagnosis of Alzheimer's Disease (AD) (Cannot be dementia from strokes or other causes) Patient is on stable and well-tolerated donepezil treatment at a dose of either 5 or 10 mg daily for at least 3 months prior to screening visit Age <55 yea... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-90.0, Central Hypothyroidism Clinical evidence of central hypothyroidism: status post pituitary surgery and/or radiotherapy plus laboratory documentation of central hypothyroidism, with or without concurrent hormonal deficiencies in other axes, such as ACTH, LH, FSH Primary hypothyroidism | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, COPD Adult patients (age > 18 years) admitted to participating ICUs with: 1. Primary diagnosis of COPD exacerbation defined as the presence of two or more of the following clinical features: worsening dyspnea, increase in sputum purulence, increase in sputum volume 2. respiratory fai... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, COPD Dyspnea Hyperinflation Current or former cigarette smokers of at least 10 pack-years Clinically significant dyspnea, as determined by a score of at least 2 on the Medical Research Council Dyspnea Score questionnaire (0-4), or through pulmonary function test results of a residual... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 25.0-89.0, Pneumococcal Infection Able to understand and give informed consent. 2. Immunocompetent community dwelling subjects between the ages of ages of 25-40 and 60-89 years Prior vaccination with pneumococcal vaccine. 2. Receipt of any of the following products: 1. Blood products within 3 m... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-90.0, Acute Lung Injury Acute Respiratory Failure Hypoxemic and no hypercapnic acute respiratory failure severe dyspnea at rest with a respiratory rate >25 breaths/min PaO2/FiO2 <300 PaCO2 <45 mmHg age <18 years NPPV contraindications past history of respiratory chronic disease (COPD, cys... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 2.0-12.0, Obstructive Sleep Apnea Enlargement of Tonsil or Adenoid Children with OSA and/or increased end tidal C02 (sleep related hypoventilation, obstructive hypoventilation or sustained alveolar hypoventilation), 2-12 years of age, and both genders will be eligible to be part of the study. OS... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, COPD Exacerbation All COPD patients (according to the ATS definition) experiencing acute exacerbation originating in acute respiratory failure and requiring ICU admission will be included in the study. COPD exacerbation is defined by the increased frequency of cough, volume and purule... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 30.0-70.0, Sleep Apnea, Obstructive Metabolic Syndrome Moderate to severe Obstructive Sleep Apnea Hypopnea Syndrome (AHI > 15/h) Sedentary patient (Activity Voorrips Questionnary score < 9,4) OSAS already treated by CPAP or other therapy (OAM,...) BMI > 40/m² Hypnotic and sedative medications C... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-70.0, Obesity Hypoventilation Syndrome Age greater than or equal to 18 years of age; less than or equal to 70 years of age Diagnosis of Obesity Hypoventilation Syndrome via a diagnostic sleep study in the past 3 months but have not initiated therapy BMI greater than or equal to 30 kg/m2 Day... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea MD diagnosis of obstructive sleep apnea No previous use of CPAP No concurrent use of hypnotic medication Fatal comorbidities (i.e., life expectancy less than 6 months) Contraindications for CPAP use Pregnancy Liver Failure | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 16.0-999.0, Chronic Hypercapnic Respiratory Failure Obesity Hypoventilation Syndrome Neuromuscular Disease Chronic Obstructive Pulmonary Disease Patients over the age of 16 years. 2. Patients with confirmed diagnosis of Duchenne Muscular dystrophy or Chronic Obstructive Pulmonary Disease or Obes... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-999.0, Periodic Breathing Breathing-Related Sleep Disorder years old Chronic ResMed ASV therapy patient Current ASV therapy for at least 4 weeks Able to understand fully the study information and participation requirements Provide signed informed consent Acute cardiac decompensation Acute ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 16.0-999.0, Pathogenesis Sjogren's Syndrome Salivary Gland Ability to sign informed consent form 2. Fulfilling one the definitions below: 1. Sj(SqrRoot)(Delta)gren s defined by European-American (EA) classification for primary or secondary Sj(SqrRoot)(Delta)gren s syndrome (SS group) 2. Excluded... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 20.0-80.0, Pulmonary Hypertension Breathing-Related Sleep Disorder percapillary pulmonary hypertension diagnosed by right heart catheterisation - stable therapy and clinical condition for at least 4 weeks sleep disordered breathing with apnea/hypopnea index > 10 events/h and/or median nocturnal ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 35.0-80.0, Chronic Obstructive Pulmonary Disease Obstructive Sleep Apnea Overlap Syndrome Patients aged > 35 years, the diagnosis of both OSA and COPD. OSA must have been diagnosed using an American Academy of Sleep Medicine (AASM)-protocol overnight Type I polysomnogram assessment with a result... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 45.0-75.0, Chronic Obstructive Pulmonary Disease Age 45 through 75 years Predicted (Global Initiative for Chronic Obstructive Lung Disease [GOLD] stage II, III, and IV) at Screening History of previous acute exacerbations of chronic obstructive pulmonary disease (AECOPD) 12 months prior to Scree... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Obstructive Sleep Apnea Syndrome Obesity BMI > 35 Complaints of snoring, sleep apnea, daytime sleepiness use of home oxygen other sleep diseases inability to perform PSG | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-999.0, Respiratory Syncytial Virus, Chronic Obstructive Pulmonary Disease, Congestive Heart Failure Key Age 50 years or greater Hospitalization due to worsening COPD and/or CHF Severe COPD subjects (Global Initiative for Obstructive Lung Disease Stage III/IV); FEV1 <50% Chronic CHF subjects... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-70.0, Sleep Apnea Syndromes Males and females, ages 21-70. 2. Able to provide written informed consent. 3. Diagnosis of chronic non-malignant pain (pain present for ≥ 6 months). 4. Stable regimen of opioids (oral, transdermal, and/or intravenous) for chronic pain for at least 4 weeks prior ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Acute Respiratory Distress Syndrome early ARDS (establishment of the diagnosis within the preceding 72 hours) according to the of the American-European Consensus Conference (5), 2. Moderate-to-severe oxygenation disturbance [defined as ratio of partial pressure of arterial oxygen (PaO... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obesity Hypoventilation Syndrome Diagnosis of OHS Age >18 BMI > 30 kg/m2 Chronic hypercapnia , daytime PaCO2 >6kPa FEV1/FVC ≥70% Evidence of sleep disordered breathing on overnight studies Tolerated NIV > 4hrs on 1st night during initiation of NIV Hypercapnic respiratory failure sec... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Dyslipidemia Patients >18 years old With Subclinical hypothyroidism defined as serum TSH concentration above 5.0 IU/mL when serum FT4 level is within the reference range With OSA defined as mild OSA: AHI 5 to 15/h; moderate OSA:AHI 15 to 30/h; and severe OSA: AHI greater than 30/h (30... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Pulmonary Disease, Chronic Obstructive Exacerbation of COPD according to the GOLD guidelines Age > 40 years Capability to use the devices provided Willing to participate included in previous COPD monitoring study | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-65.0, Community-acquired Infection AST, ALT, alkaline phosphatase and bilirubin ≤ 1.5xULN (isolated bilirubin >1.5xULN is acceptable if bilirubin is fractionated and direct bilirubin <35%) Healthy adult male Japanese or healthy adult Caucasian male. In Part B, healthy adult males or females... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-85.0, Nonhemorrhagic Ischemic Stroke Motor Function Male or female participants between 21 and 85 years, inclusive Participants had no prior history of stroke (unless the stroke was silent or not associated with a motor deficit) presented between 24 and 48 hours from onset with an acute str... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Respiratory Insufficiency Adults aged ≥ 18 years 2. Males 3. Females 4. Any patient requiring mechanical ventilation for 5 days or more and/or has a tracheostomy to assist weaning from mechanical ventilation who has one or more of following risk factors suggesting that they are at ri... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Pulmonary Disease, Chronic Obstructive Obesity Hypoventilation Syndrome Metabolic Alkalosis Patients with COPD or obesity hypoventilation syndrome on invasive mechanical ventilation during less than 72 h with metabolic alkalosis, defined as a pH > 7.35 and actual bicarbonate > 28 mmo... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-75.0, Obstructive Sleep Apnea Sleep Apnea Sleep-disordered Breathing Ability to give informed consent Obstructive sleep apnea (untreated) Ability to comply with study-related assessments Inability to consent or commit to the required visits Diabetes mellitus (fasting glucose > 126 mg/dl) U... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Pulmonary Disease, Chronic Obstructive Exacerbation of COPD Age > 40 years Capability to use the devices provided Willing to participate • Participation in a previous COPD home telehealth study | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Chronic Obstructive Pulmonary Disease Acute Exacerbation of Chronic Obstructive Airways Disease Chronic Hypercapnic Respiratory Failure Patient admitted with a NIV-requiring exacerbation of COPD COPD with a FEV1/FVC <0.7 after bronchodilatation ≥ 1 acute hypercapnic respiratory failur... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Chronic Obstructive Pulmonary Disease (COPD) Decompensated COPD With (Acute) Exacerbation Patients with Chronic Obstructive Pulmonary Disease Age > 18 years Hospitalized in Intensive care for an acute exacerbation Requiring Non invasive mechanical ventilation Able to breath spontaneo... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-70.0, Overlap Syndrome Patient or legal representative of the patient is willing and able to sign an approved informed consent and privacy protection authorization in the United States. 2. Subject is >18 years old. 3. Diagnosed overlap syndrome(OSAS and COPD). 4. Expected to tolerate the ve... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Pancreatic Cancer Hypoxia Minimum age of 18 years old Histologic diagnosis of pancreatic adenocarcinoma TNM (7th edition) cT1-4, N0-1, M0-1 No cytotoxic anti-cancer therapy for advanced / metastatic pancreatic cancer prior to study entry Ability to provide written informed consent to... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 60.0-89.0, Osteoarthritis, Knee Adults aged 60 years of age primary unilateral TKA 10-21 days prior to the outpatient PT evaluation received inpatient rehabilitation at Helen Hayes Hospital Any other lower extremity joint or back pain (not inclusive of recent Total knee arthroplasty) rated grea... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-70.0, Sleep Apnea, Obstructive Obesity Hypoventilation Syndrome Patient or legal representative of the patient is willing and able to sign an approved informed consent and privacy protection authorization in the United States. 2. Subject is >18 years old. 3. Diagnosed OHS and OSAHS: 4. Expe... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-90.0, Chronic Obstructive Pulmonary Disease Pulmonary Hypertension Cor Pulmonale diagnosis of COPD stage II, III or IV according to the GOLD guidelines signed the informed consent ischemic cardiopathy severe valvular disease atrial fibrillation left bundle branch block | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 15.0-80.0, Chronic Obstructive Pulmonary Disease Neuromuscular Disease Chest Wall Disorders Obesity Hypoventilation Syndrome OHS PaCO2 > 45 mmHg IMC > 40 Kg/m2 COPD Age < 80 years Receiving appropriate medical therapy according to gold guidelines Long-term oxygen therapy (LTOT) for at least 3 mo... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 55.0-999.0, Alzheimer's Disease Meets for MCI due to AD or Mild AD All participants will be required to undergo assessment via the Mini Mental State Examination (MMSE) scale at screening Participants with MMSE scores of 20 to 26, inclusive, may be enrolled provided they meet the for mild AD, as ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Postoperative Pain All patients over 18 years of age Isolated thoracoscopic procedure for therapeutic or diagnostic purposes Previous ipsilateral thoracic surgery Need for operative pleurectomy or pleurodesis Chronic use of pain medication (narcotics or sedatives or hypnotics Allerg... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Hypopituitarism All patients with pituitary hypopituitarism Unavailability of data | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-90.0, Stroke Motor Function (1) All subjects must be between the ages of 18-90 History of Major depression, as defined by Beck Depression scale 30; 2. Any substantial decrease in alertness, language comprehension, or attention that might interfere with understanding instructions for motor ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Pulmonary Thromboembolism Obstructive Sleep Apnea All consecutive patients diagnosed with pulmonary embolism less than 18 years of age any restrictive or obstructive lung disease | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-90.0, COPD OSA Age ≥ 21 Diagnosis of COPD Currently using Bilevel device for COPD-OSA overlap syndrome Ability to provide consent Documentation of medical stability by PI Subjects, who are acutely ill, medically complicated or who are medically unstable Subjects in whom PAP therapy is othe... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 35.0-999.0, Chronic Obstructive Pulmonary Disease Is over the age of 35 years 2. Has a history of COPD confirmed by physician diagnosis 3. Has been admitted to the hospital with a working diagnosis of acute exacerbation of COPD (AECOPD) defined as at least two of the following progressive sympto... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Sleep Apnea, Obstructive Patients who underwent uvulopalatopharngoplasty (UPPP)for Obstructive sleep apnea syndrome (OSAS) Anormal nasopharyngeal computed tomography, chronic diseases such as diabetes mellitus, hypertension etc | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Functional Dyspepsia Peptic Ulcer patients who presented with upper gastrointestinal symptoms and endoscopically proven H.pylori-positive functional dyspepsia and scarred peptic ulcer patients with peptic ulcer, previous H.pylori eradication therapy, previous gastric surgery, pregnan... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-80.0, Chronic Obstructive Pulmonary Disease (COPD) With Cachexia Written informed consent must be obtained before any assessment is performed Males and females ages 40 to 80 years Smoking history of at least 10 pack-years Diagnosis of COPD according to GOLD guidelines (GOLD, 2010), with a p... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 16.0-999.0, Community-acquired Pneumonia Patients with community-acquired pneumococcal pneumonia, which was confirmed by 1. detection of Streptococcus pneumoniae in blood cultures, tracheal secretion or sputum OR/AND 2. positive urinary pneumococcal antigen AND 3. presence of cough and presence ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Pulmonary Disease, Chronic Obstructive All patients must sign an informed consent consistent with International Conference on Harmonization-Good Clinical Practice (ICH-GCP) guidelines prior to participation in the trial, which includes medication washout and restrictions. 2. All pati... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Pulmonary Disease, Chronic Obstructive Diagnosis of chronic obstructive pulmonary disease 2. Relatively stable airway obstruction with post FEV1=<30% of predicted normal and< 80% predicted normal and post FEV1/FVC <70% 3. Male or female Japanese patients, 40 years of age or older 4. ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Chronic Obstructive Pulmonary Disease Patients with stable, symptomatic Chronic Obstructive Pulmonary Disease (COPD) with airflow obstruction of level 2 and 3 according to the current Global initiative for chronic Obstructive Lung Disease (GOLD) strategy (2011). 2. Patients with Forc... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 45.0-999.0, COPD COPD subjects Ability to walk, sit down and stand up independently Age 45 years or older Ability to lie in supine or elevated position for 5.5 hours Diagnosis of moderate to very severe chronic airflow limitation and compliant to the following Forced Expiratory Volume(FEV1)/Forc... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Chronic Kidney Disease Subject is ≥ 18 and ≤75 years of age. 2. A serum creatinine level of 1.5 to 5.0 mg per deciliter (133 to 442 μmol per liter), a creatinine clearance of 20 to 70 ml per minute per 1.73 m2, with variations of less than 30 percent in the three months before randomi... | 0 |
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