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70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Glioblastoma Hypoxia Adult (>18 year old) patients with newly diagnosed GBM presenting to our centre for surgical management and post-operative chemoradiation 2. Creatinine clearance > 60 ml/minute 3. Able to tolerate an MR scan 4. Capable of providing informed consent Prior brain s... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Congestive Heart Failure ≥ 18 years of age Presenting to clinic with worsening heart failure due congestion (fluid overload) Patient reported worsening fluid overload based on perception of edema and/or weight gain With at least one of the following symptoms Worsening dyspnea on exer... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Obesity Premature Recovery From Anesthesia Patient presented for surgery under general anesthesia Documented OSA Patients with BMI above 35 Coronary Artery Disease or Myocardial infarcts Mitral valve prolapse Cyclosporine, contraceptive drugs Known allergic reaction to Modafinil or a... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obesity Hypoventilation Syndrome Aged 18+ Diagnosed with OHS by a practicing physician Existing full face mask user or a nasal mask user Prescribed PAP therapy (Bi-Level or CPAP) Inability to give informed consent Pregnant or think they may be pregnant Anatomical or physiological co... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 20.0-75.0, Sleep Apnea, Obstructive Objectively confirmed OSA (at the time of original diagnosis) with an oxygen desaturation index (ODI) and apnoea-hypopnoea-index (AHI) of ≥20/h Currently an oxygen desaturation index (≥4% dips) of ≥15/h during an ambulatory nocturnal pulse oximetry performed o... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 55.0-999.0, Atrial Fibrillation Participants: The study population will be derived from the Aetna and Medicare populations Male or females age > 75 or Male age > 55, or females age > 65, and Prior CVA, or Heart failure, or Diagnosis of both diabetes and hypertension, or Mitral valve disease, or ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Colorectal Cancer Patient with metachronous or synchronous metastases of a colorectal cancer progression under standard therapy no proven brain metastases no curative option no standard therapy available Age > 18 years At least one metastases measurable according to Response Evaluati... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea Syndrome Clinical presentation of ischemic stroke confirmed by imaging (CT or MRI brain scan) less than 24 hours from onset of symptoms admitted to the Neurovascular unit of the Emergency Hospitalisation Department of 'Hôpital Nord' of the university hospital ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-70.0, Hypoxemia Trauma Acute Myocardial Infarction to 70 years of age Male and female volunteers ASA physical status I, II and III Capable and willing to provide written informed consent in English Acute cardiopulmonary disease, as defined by blood pressure greater than 150/90, HR greater ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Hypothyroidism Neoplasms Postoperative Complications Biopsy proven head and neck cancer, as defined by AJCC staging system Treated with surgery in Edmonton, Alberta Treated with curative intent Diagnosis of sub-clinical hypothyroidism after head and neck surgery (TSH 4-10mIU/L, and fr... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-70.0, Obstructive Sleep Apnea for COPD Subjects Age range 40-70 years Demonstrated moderate to severe COPD as determined by spirometry (post-bronchodilator spirometry FEV1/FVC < 0.70 for diagnosing CODP and FEV1<80% predicted for staging) Smoking history of ≥ 10 pack-years for Control Subje... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, COPD Home Care Oxygen Therapy informed consent acute on chronic respiratory distress | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 20.0-50.0, Hypoxia Diabetes Mellitus, Type 1 Patients with typ1 diabetes with a duration of the disease between 10-20 years (HbA1c ≥ 65 mmol /l) 2. Healthy controls matched for age, BMI and gender on group bases Smoking 2. Infections during the last month 3. Major cardiovascular complications s... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Obesity, COPD, OHS age ≥ 18 years patients with COPD (GOLD I-IV Group A-D) with obesity (BMI> 30kg/m2), obese healthy adults with BMI> 30kg /m2, patients with Obesity hypoventilation syndrome informed consent provided patients less than BMI <30 kg/m2 with or without COPD, OHS Age < 1... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-80.0, Chronic Obstructive Pulmonary Disease Patients with Chronic Obstructive Pulmonary Disease (COPD) in Global Initiative on Obstructive Lung Disease (GOLD) stages II to IV COPD patients with mild to moderate cognitive impairment (MCI-group: n=100) and without cognitive impairment (Contro... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Ventricular Tachycardia Patients undergoing radiofrequency catheter ablation for scar VT which includes VT secondary to ischemic cardiomyopathy and non-ischemic cardiomyopathy Women of childbearing potential (WOCBP) must have a negative serum or urine pregnancy test within 24 hours pr... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-85.0, Chronic Obstructive Pulmonary Disease Age > 21 years of age; < 85 years of age Participants that have been physician diagnosed (primary diagnosis) with Obstructive Airway Disease (to include:Chronic Obstructive Pulmonary Disease (COPD); Bronchiectasis; Severe Asthma); forced expirator... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Congestive Heart Failure FOCUS 1. Remotely monitored with CRT-CIED focus groups 1 & 2: implant ≤ 12 months focus groups 3 & 4: implant ≥ 12 months 2. Current patient of PPG-Cardiology 3. History of HFrEF (heart failure in the setting of reduced ejection fraction) 4. Access to compute... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Upper Airway Obstruction Respiratory Insufficiency Respiratory Failure for the study are: 1. Participant has ability to provide written informed consent 2. Participants aged ≥18 years old 3. Participant has documented respiratory failure (e.g. sleep hypoventilation with historical Pt... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 4.0-99.0, Methicillin-Resistant Staphylococcus Aureus Cystic Fibrosis Male or female with a confirmed diagnosis of CF (clinical features and positive sweat test and/or identification of 2 CF disease causing mutations). 2. At least 4 years of age or older. 3. Chronic infection with MRSA defined a... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 30.0-64.0, Myalgia Apnea, Obstructive Sleep Any race or ethnicity Meet Research Diagnostic for TMD to confirm Group II: Masticatory Muscle Disorders, 1A: Myalgia Rate their TMD pain severity as ≥4 on a 0-10 numeric rating scale Have no history of treatment for OSA. If taking a prescription medic... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-70.0, Sleep Apnea, Obstructive; Post-Traumatic Stress Disorders Normal sleep study aside from elevated AHI Prior home sleep test (HST) or polysomnogram with results consistent with mild, moderate, or severe sleep apnea. If a sleep study has not been performed in the past, the participant wi... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Obstructive Sleep Apnea Study Aged ≥ 18 and ≤ 80 Ability and willingness to provide written informed consent AHI ≤ 15 as per AASM 2007 scoring Ability to tolerate a CPAP one hour long run in test The presence of unstable cardiac disease Inability to give fully informed consent Supple... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 60.0-89.0, Obstructive Sleep Apnea OSA COPD Overlap Syndrome OSA defined by the International classification of Sleep Disorders-322 diagnostic with moderate-to-severe disease, i.e. apnea hypopnea index (AHI) 15* per hour by polysomnography Moderate-to-severe COPD defined by GOLD 2 and 3 (Global ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Pain Male or female, at least 18 years of age at screening. 2. Scheduled to undergo primary unilateral TKA under general or spinal anesthesia. 3. American Society of Anesthesiologists (ASA) physical status 1, 2, or 3. 4. Female subject must be surgically sterile; or at least 2 years ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea years and older Ability to speak, read, and write Dutch Ability to follow-up Ability to use a computer with internet connection for online questionnaires Diagnosis with symptomatic mild or moderate OSA (5 < AHI < 30) Expected to maintain current lifestyle (spo... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Sleep Apnea Syndromes OSA 1. Age greater than 18 years 2. Able to provide informed consent 3. New diagnosis of OSA by polysomnogram 4. Agree with CPAP treatment Control 1. Age greater than 18 years 2. Without OSA 3. Able to provide informed consent Not able to give informed consent ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obesity Hypoventilation Syndrome Obstructive Sleep Apnea Chronic Obstructive Pulmonary Disease Neuromuscular Disease Aged 18+ Existing full face mask user or a nasal mask user Prescribed NIV therapy for at least 3 months Inability to give informed consent Pregnant or think they may ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-45.0, Invasive Aspergillosis Subjects will be males and females of any ethnic origin aged between 18 and 45 years of age and weighing 50-100 kg inclusive. 2. Subjects must be in good health, as determined by a medical history, physical examination, 12-lead electrocardiogram (ECG) and clinic... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 5.0-12.0, Pediatric Sleep Apnea Obesity Morphine Metabolism Child presenting for surgery that will require opioids Age between 5 -12 years of age OSAS group Pre-operative polysomnography study conducted prior to day of surgery Obese Body weight >95th percentile for age Emergency procedures invo... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-55.0, Dizziness Adult patients who were experiencing sudden onset dizziness of unknown etiology for the first time were included in the study Patients with a history of chronic diseases such as any liver disease,diabetes mellitus, hypertension,congestive heart failure, hepatitis B or C inf... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Asthma for Phase I For the WTC population with Irritant-Induced Asthma (IA) > 18 years of age* Current nonsmoker* < 5 pack year (p-y) history of tobacco use* Spirometry in the past 6 months or on day of evaluation with a bronchodilator* response of ≥ 12% and 200 ml improvement in FEV*... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea Consecutive adult patients with newly diagnosed obstructive sleep apnea (apnea-hypopnea index ≥5 events/h), who were offered PAP treatment Must be able to give informed consent Disabled to come to follow-ups | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.167-4.917, Pneumonia History of cough <14 days or difficult breathing with fast breathing (for children 2 to <12 months of age, >50 breaths/minute and for children >12 months of age, > 40 breaths/minute) Ability and willingness of children's caregiver to provide informed consent and to be avai... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Heart Failure Myocardial Infarction Ventricular Tachycardia Post-MI patients eligible for ICD implantation in the setting of primary prevention NYHA IV or ambulatory NYHA IV 2. Acute coronary syndrome in the last 40 days 3. Stable angina not eligible to revascularization 4. Revascula... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-70.0, Chronic Disease Obstructive Pulmonary individuals who have been diagnosed with COPD , stage II and III disease are undergoing treatment at the hospital João de Barros Barreto in the period January and February 2016 both sexes to 70 years of age hemodynamically stable were not diagnos... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea All adult surgical patients (>18 yr) with a diagnosis of OSA with or without a CPAP prescription. 2. Scheduled for a non-cardiac surgery (general surgery, orthopedics, urology, plastic surgery and spine) that is expected to require a postoperative hospital sta... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 45.0-75.0, Work of Breathing • COPD Diagnosis: mild-to-moderate, with FEV1 30-80% and requiring no long-term oxygenotherapy Refuse to participate in the study for one of the following reasons: i. wearing a oesophageal catheter; ii. wearing the gas mask; iii. giving blood sample; iv. claustropho... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 22.0-999.0, Obstructive Sleep Apnea Aged 22 and over Diagnosed with Obstructive Sleep Apnea (OSA) and prescribed Positive Airway Pressure (either Continuous positive airway pressure (CPAP) or AutoCPAP) For experienced users of PAP (CPAP or AutoCPAP) you must be using PAP of more than 4 hours/nig... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 50.0-90.0, Alzheimer's Disease Obstructive Sleep Apnea Patients diagnosed of mild probable AD according to NIA-AA (MMSE>20). 2. Informed Consent Form signed by the patient (and/or if applicable the legal representative if different from the responsible caregiver) and the responsible caregiver. 3... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 35.0-80.0, Chronic Obstructive Pulmonary Disease One previous chronic obstructive pulmonary disease exacerbation in last year Can not be oxygen dependant PaCO2 < 60 | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Ventricular Tachycardia (VT) Prior Myocardial Infarction and One of the following VT events while not being treated with amiodarone, sotalol, or another class I or class III antiarrhythmic drug) within the last 6 months Sustained monomorphic VT documented on 12-lead ECG or rhythm str... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 25.0-60.0, Sleep Apnea, Obstructive Obesity Patients who have been diagnosed with severe obstructive sleep apnea syndrome (AHI > 30) and are already receiving CPAP treatment (since at least 6 months), who have class I and class II obesity (body mass index (BMI) >= 30 kg /m2 y <= 40 kg/m2) disea... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 65.0-999.0, Thyroid Dysfunction Atherosclerosis Heart Failure Community-dwelling patients aged >= 65 years with subclinical hypothyroidism Written informed consent Subjects currently under levothyroxine or antithyroid drugs (amiodarone, lithium) Recent thyroid surgery or radio-iodine (within 12... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 45.0-99.0, Obstructive Sleep Apnea Arrhythmia orthopaedic, urologic, vascular, digestive surgery under general anaesthesia or sedation age > 45 years old STOP-BANG score>3 Head and neck surgery, planned prolonged mechanical ventilation after surgery (>24h) Severe COPD Post-operative ICU planned... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Postoperative Pain ASA I-III subjects Ages 18-80 years Weight between 60 and 110 Kg At least 60in (152cm) tall Scheduled for elective open colonic surgery at UPMC Presbyterian Shadyside Hospital in Pittsburgh, Pennsylvania Age younger than 18 years or older than 80 years Any contrain... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 15.0-999.0, Pulmonary Disease, Chronic Obstructive Patients who have been diagnosed with chronic obstructive pulmonary disease (chronic bronchitis, emphysema) by physician and need relief of various symptoms associated with Long Acting Beta2 Agonist (LABA) or Long Acting Muscarinic Antagonist (L... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Chronic Obstructive Pulmonary Disease (COPD) Sleep Apnea Obstructive (OSA) Healthy Volunteers COPD patients stages GOLD III IV, FEV1/FVC ratio < 0,7 and maximum voluntary ventilation (MVV) < 50% of predicted values BMI < 30 kg/m² Age between 18 and 80 years Non-smoking or ex-smoker (s... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-65.0, Influenza, Human Subjects with acute uncomplicated influenza with oral temperature ≥ 37.8 ℃ (100.04 °F); plus at least one respiratory symptom (nasal congestion, sore throat, cough); and at least one constitutional symptom (aches or pains, fatigue, headache, chills or sweats). If anti... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 16.0-86.0, Refractory Epilepsy Patients with refractory focal epilepsy Initiation of perampanel between 05/2014 and 04/2015 Exact date of initiation of Perampanel not defined Patients without follow-up data | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Chronic Obstructive Pulmonary Disease Already on primary care COPD register and DOSE score <4 (low risk) No capacity to consent or unable to travel to primary care practice (local GP surgery) | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 1.0-31.0, B Acute Lymphoblastic Leukemia Central Nervous System Leukemia Ph-Like Acute Lymphoblastic Leukemia Testicular Leukemia Patients must be enrolled on APEC14B1 and consented to Screening on the Part A consent form prior to enrollment on AALL1131 White Blood Cell Count (WBC) Age 1-9.99 ye... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 20.0-75.0, Hypothyroidism TSH > 10 mU/liter Serious competing illness Pregnancy or planning to become pregnant Thyroidectomized patients Unable to speak and understand danish | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 19.0-70.0, Lipedema Ambulatory females of any race able to understand the consent process. 2. 19-70 years of age. 3. Diagnosis of lipedema Stage 1 or Stage 2 although early Stage 3 will be considered. 4. Weight stable for past three months per personal report of the subject. 5. Must be able to a... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 65.0-999.0, Frail Elderly Exercise Therapy Physical Therapy Techniques volunteers above the age of 65 who are community residents and classified as frail according to the established by Fried et al. will be selected for in the study previous lower extremities orthopedic surgery, a history of fr... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea Adult patient Obstructive Sleep Apnea Patient previously treated by Continuous positive airway pressure non-compliant to therapy Patient naive of bilevel Positive Airway Pressure therapy Bilevel positive airway pressure Contraindication Severe respiratory dis... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-55.0, Healthy Volunteers Premenopausal women and men <55 years of age Body weight <204 kg (<450 pounds) and >= 36 kg (>= 80 pounds) Stable weight (+/-5% within past 6 months) as determined by volunteer report Healthy, as determined by medical history, physical examination, and laboratory te... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Acute Respiratory Failure Patients over 18 years of age Competent or with legal representative able to sign inform consent Reversible ARF secondary to heart failure, COPD exacerbation, pneumonia, or at risk of pot-extubation failure* who meet the for starting NIV Signs and symptoms o... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 60.0-999.0, Mild Cognitive Impairment Major Depressive Disorder Alzheimer's Dementia Transcranial Direct Current Stimulation tDCS MCI Group 1. Age > 60 (on day of randomization) 2. DSM-IV for Mild Neurocognitive Disorder ("MCI") 3. Willingness to provide informed consent 4. MADRS score of 10 or ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obstructive Sleep Apnea Aged 18 and over Diagnosed with OSA by a practicing physician and prescribed Positive Airway Pressure (PAP) (Continuous Positive Airway Pressure (CPAP) or AutoCPAP). Participants can be naïve to CPAP or experienced users of CPAP For experienced users of PAP (C... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, GERD for Healthy Persons: -Patients 18 years of age or older with no symptoms of GERD for Patients Patients 18 years of age or older with symptoms of GERD Upper gastrointestinal endoscopy within the past 6 months and a prior diagnostic pH impedance study showing predominantly upright... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-999.0, Chronic Disease Arms 1 & 2 Candidates to major elective surgical procedures in the following specialties: abdominal, gynecology, cardiovascular, urology and thoracic Patients presenting high surgical risk because they are they are aged > 70 years and/or show an American Society of Ane... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Obstructive Sleep Apnea Obesity Hypoventilation Syndrome Hypercapnia Post-Op Complication Acid-Base Imbalance Patients undergoing elective abdominal surgery Body-Mass-Index >=30 kg/m2 Ability to read and speak Signed informed consent Use of diuretics Use of theophylline Use of respir... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Chronic Obstructive Pulmonary Disease (COPD) Adult patients with frequent exacerbations of COPD (clinically dominant COPD in the case of multiple co-morbidities eg. bronchiectasis, interstitial lung disease, congestive heart failure) Confirmed diagnosis of COPD (bronchodilator FEV1/F... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Sleep Apnea, Obstructive All patients scheduled to have a PSG in the sleep laboratory center Patients < 18 years | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Observation Subjects are participants in a previously described dietician-based weight loss study in obese Chinese with obstructive sleep apnea (OSA). Specific study entry included an age range between 30 and 80 years, body mass index (BMI) >25 kg/m2, and moderate to severe OSA (apne... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-90.0, Rehabilitation Recovery of Function Stroke experienced unilateral hemispheric ischemic or hemorrhagic stroke at least 3 months but no more than 7 years prior exhibit voluntarily shoulder flexion of the affected arm ≥30° with simultaneous elbow extension ≥20°. The investigators reason ... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 70.0-100.0, Unrecognized Condition Age equal or greater than 70 years of both sexes Patients with sleep study results with AHI ≥ 15 and < 30 Alternative diagnoses of other non-respiratory sleep disorders that are also cause of pathological somnolence (eg, sdr restless legs, narcolepsy, etc.) Do... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-85.0, Neuromuscular Diseases Obesity Hypoventilation Syndrome Lung Disease, Restrictive Home non-invasive mechanical ventilation and clinical stability at least of 6 months ( no acute episode with admission on 2 months before) Mean Ventilator compliance > 4 h/ per night on screening visit S... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Chronic Obstructive Pulmonary Disease Admitted with COPD exacerbation as a primary diagnosis Subjectively produces more than 1 tablespoon (15 ml) / day of sputum Has the subjective feeling that he/she cannot cough up or clear her secretions Physical respiratory system exam by the phy... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Elevated Blood Pressure Hypertension Mental Stress Sleep Disorders User of a (1) Withings blood pressure cuff (2) Withings activity tracker and (3) Withings Body Cardio scale User has measured their blood pressure at least once per week for the majority of weeks over the last three m... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 20.0-40.0, Constipation - Functional Patients whose BMI exceeded 30 kg/m2 were included. In addition, they fulfilled the ROM of constipation, as follows: 1. Suffered from any 2 or more of the following symptoms in the past 12 weeks (not necessarily consecutive), with the onset of symptoms at lea... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-85.0, Traumas, Brain Alzheimer Disease Dementia Head Injury Concussion, Brain TBI individuals aged 18 2. distress associated with being the primary caregiver of a person with TBI or dementia 3. endorsement of at least two of the following items: felt overwhelmed, felt like needed to cry, an... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-70.0, Graves Ophthalmopathy Thyroid Associated Ophthalmopathy Thyroid Associated Orbitopathy Age 18-70 years 2. Active mild to moderate with at least one sign of mild GO (NO SPECS class 2a and b) with reference to Colour Atlas at website (www.eugogo.eu). Exophthalmos up to 24 mm with a dise... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 19.0-999.0, Stroke Rehabilitation Motor Function Acute first-ever stroke Upper limb score of Fugl-Meyer assessment at 7 days after onset : 25~84 Transient ischemic stroke Joint contracture of affected upper extremity | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-75.0, Sleep Apnea, Obstructive Hypertension Age between 18 and 75 years Apnea-Hypopnea Index (AHI) ≥ 15 events/hr on diagnostic polysomnography(PSG) No previous history of surgical treatment of OSA, and no medical treatment of OSA within the past 6 months Adherence to prescribed anti-hypert... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Hypothyroidism examined for thyroid stimulating hormone, free thyroxine, thyroid peroxidase antibody (TPO Ab), and urine iodine concentration (UIC) already have a thyroid disease(benign thyroid diseases or thyroid cancer) | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, COPD Sleep Apnea Syndromes COPD patients with informed consent pregnant patients, patients with serious respiratory diseases other than COPD, patients with limited life expectancy, patients that can't coordinate well | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, Pain The subject is scheduled for elective unilateral TKA; 2. The subject is ≥ 18 years and ≤ 80 years; 3. The subject's weight is between 65-130 kg; 4. The subject's primary anesthesia care team has planned for a neuraxial anesthetic (i.e. spinal, epidural or combined-spinal epidural... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-75.0, COPD Sleep Apnea Syndromes Non-invasive Positive Pressure Ventilation patients with COPD and sleep apnea dyspnea syndrome patients with non-stable hemodynamics patients with limited life expectancy patients with other severe respiratory diseases patients with motor neuron diseases pa... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, COPD Pulmonary Vascular Disorder Right Ventricular Dysfunction stable COPD patients patents with other respiratory diseases and pulmonary hypertension other than group 3 PH psychopath, addict or patients not able to coordinate patients in pregnancy or breastfeeding patients with lim... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.0-80.0, COPD Anxiety Depression Stable chronic obstructive pulmonary disease (COPD) patients Patients with bronchial asthma or other severe pulmonary diseases or having received pulmonary surgery in 6 months Patients with tumor history during past 5 years Patients with COPD exacerbations duri... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Agitation,Psychomotor Emergency Department patients (18+) with acute undifferentiated agitation requiring chemical sedation at the discretion of the attending emergency physician Known pregnancy Allergy to the medication during the block Prisoner/under arrest | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Pulmonary Disease, Chronic Obstructive Hypercapnia Hypoxia admitted to the hospital for an acute exacerbation of COPD within the past 12 weeks have COPD as the primary diagnosis have smoked > 10 pack years receiving supplemental oxygen as part of their usual clinical care willing to ... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 20.0-70.0, Obesity Obstructive Sleep Apnea Bariatric Surgery Candidate BMI above 30 kg/m2 Age between 20 and 70 years Willingness to understand the protocol and willingness to participate in the study is severe co-morbidities that would prevent the patients to undergo bariatric surgery. Such as... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Pulmonary Disease, Chronic Obstructive, Severe Early-Onset Episodes of patients with exacerbation of chronic obstructive pulmonary disease (COPD). Those patients can be admitted with 2 presentations: A) known case of COPD: episodes of patients with a previous diagnosis of COPD (FEV1/... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Acute Respiratory Failure With Hypercapnia Hypoxemic and no hypercapnic acute respiratory failure severe dyspnea at rest with a respiratory rate >25 breaths/min PaO2/FiO2 <300 PaCO2 <45 mmHg age <18 years NPPV contraindications past history of respiratory chronic disease (COPD, cys... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 55.0-90.0, Chronic Obstructive Pulmonary Disease Age > 55 years COPD patients with confirmed pulmonary function test results of FEV1<70% Regular follow-up at the pulmonary medicine clinic Stable condition without acute exacerbation No pulmonary rehabilitation training within a year None oxygen u... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-80.0, COPD Hypercapnic Respiratory Failure Clinically stable with chronic hypercapnic COPD (baseline arterial carbon dioxide pressure (PaCO2) of 50 mmHg or higher, measured resting in a sitting position and breathing room air without having used NPPV for at least 1 hour) other lung/pleural... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Chronic Obstructive Pulmonary Disease Age > 18years Chronic obstructive pulmonary disease stade III to IV Referred for pulmonary rehabilitation. Non Pregnancy or likely to be History of psychiatric, neuro-vascular, cognitive disease or cranial trauma Active alcoholism Guardianship Ho... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 21.0-999.0, Chronic Heart Failure Central Sleep Apnea patients with heart failure and reduced ejection fraction (LVEF < 45%) due to ischemic or hypertensive heart disease moderate to severe central sleep apnea/cheyne stokes respiration treatment should be stable for the last 30 days preceding en... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 40.0-999.0, Acute Exacerbation of COPD Age ≥ 40 years 2. Confirmed diagnosis of underlying COPD or ACOS (Asthma-COPD Overlap Syndrome) 3. Experiencing acute hypercapnic respiratory failure 4. Informed consent from patient or legally authorized representative 5. Meets one of the three following 1... | 2 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-80.0, COPD Asthma Patients with asthma or chronic obstructive pulmonary disease (COPD) Invasive mechanical ventilation Hemodynamically stable Prescribed metered dose inhaler (MDI) or intravenous bronchodilators Undrained pneumothorax Bronchopleural fistula Chest trauma Tracheoesophageal fi... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Obesity Obstructive Sleep Apnea Syndrome Patients over 18 years of age male or female obesity defined by a body mass index (BMI = weight in kg / height in m²) ≥ 30 free from acute or chronic painful pathology free from any chronic analgesic treatment free from any psychotropic treatm... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 30.0-70.0, Safety and Tolerability non-diabetic subjects with asthma, or COPD. Non-smokers or smokers quit at least 6 months prior to enrollment. BMI <= 35 kg/m2. Fasting blood glucose <= 125 mg/dL pulmonary disorder other than asthma or COPD. Upper respiratory within previous 4 weeks. Signific... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Oxygen Inhalation Therapy Regardless of gender, at least 18 years of age and diagnosed with severe Hypoxia (PaO2/FiO2 < 300 mm Hg), dyspnea with severe rest at stake accessory muscles of respiration, respiratory rate (RR) ≥ 25 CPM, PaCO2 ≤ 45 mmHg, patient with an arterial catheter a... | 1 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 0.615-0.692, Intermittent Hypoxia Male and female infants born preterm at ≤30 weeks + 6 days post menstrual age 2. Current treatment with routine caffeine 3. PMA 32 weeks + 0 days weeks + 6 days 4. Anticipated last dose of routine caffeine will be by 36 weeks + 5 days 5. At least 12 hours of bre... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 18.0-999.0, Community-acquired Pneumonia for suspected CAP population Age ≥18 years Presence of at least 2 signs suggestive of CAP on presentation at general practice (one general sign of infection and one sign of pulmonary localization) at least one sign of infection fever > 38.5°C (maximum tem... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 60.0-999.0, Agitation Related to Dementia Male or female subjects > 60 years old Written informed consent from participants legally authorized representative Subjects who are residing either in an institutionalized setting (e.g. dementia unit, nursing home, assisted living facility, or other res... | 0 |
70 y/o with COPD on 2.5-3.5L O2 at baseline, OSA and obesity hypoventilation syndrome, dCHF, discharged [**2132-8-24**] now presents with agitation and altered mental status with hypoxia and O2 sats 70s on BipAp with 5L. Pt agitated then somnolent at initial presentation. Daughter reported increased agitation and alter... | eligible ages (years): 8.0-12.0, Pediatric Obesity Executive Function Have a BMI ≥ 85th percentile 2. Are ≥8 and ≤12 years old at the beginning of treatment 3. Can read, write, and speak English, along with their parent 4. Plan to stay living within the local area during the study period 5. Have a consenting parent wh... | 0 |
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