E3_UniProtID
string | Sub_UniProtID
string | Reference
string | Source
string | E3_Gene_Name
string | E3_Sequence
string | E3_Species
string | E3_Subcellular_Location
string | E3_HPA_Expression
string | E3_scRNA_Data
string | E3_PDB_IDs
string | E3_GTEx_expression
string | Sub_Gene_Name
string | Sub_Sequence
string | Sub_Species
string | Sub_Subcellular_Location
string | Sub_HPA_Expression
string | Sub_scRNA_Data
string | Sub_PDB_IDs
string | Sub_GTEx_expression
string | E3_Confidence_Scores
string | E3_Relative_SASA
string | Sub_Confidence_Scores
string | Sub_Relative_SASA
string | E3_Type
string | E3_Complex
string | Complex_name
string | Susbtrate_specificity
string | E3_Known_direct_interactions
string | E3_Substrates
string | PolyUb_Lys
string | C/N_end
string | Associated_E2
string | Self_oligomerization
string | Atypical_AA_ubi
string | E3_Confidence_Scores_Avg
float64 | E3_Relative_SASA_Avg
float64 | Sub_Confidence_Scores_Avg
float64 | Sub_Relative_SASA_Avg
float64 | ClusterID
int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
O43255
|
P46527
|
21734459
|
UbiNet, UbiBrowser
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
CDKN1B
|
MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
|
Homo sapiens
|
Nucleus, Cytoplasm, Endosome
|
Low tissue specificity
|
{'Ciliated cells': '25.5', 'Basal respiratory cells': '19.8', 'Club cells': '33.9', 'Ionocytes': '17.3', 'Mucus glandular cells': '26.7', 'Serous glandular cells': '25.5', 'Gastric mucus-secreting cells': '21.2', 'Proximal enterocytes': '32.3', 'Paneth cells': '26.7', 'Distal enterocytes': '26.4', 'Intestinal goblet cells': '43.2', 'Exocrine glandular cells': '-0.402', 'Basal prostatic cells': '53.1', 'Prostatic glandular cells': '52.2', 'Breast glandular cells': '0.569', 'Breast myoepithelial cells': '0.552', 'Glandular and luminal cells': '35.5', 'Secretory cells': '17.9', 'Basal keratinocytes': '48.9', 'Suprabasal keratinocytes': '45.4', 'Basal squamous epithelial cells': '108.4', 'Squamous epithelial cells': '94.2', 'Alveolar cells type 1': '0.268', 'Alveolar cells type 2': '-0.454', 'Salivary duct cells': '18.6', 'Ductal cells': '0.390', 'Hepatocytes': '0.427', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.182', 'Distal tubular cells': '12.3', 'Collecting duct cells': '7.8', 'Mesothelial cells': '0.360', 'Sertoli cells': '0.710', 'Granulosa cells': '34.9', 'Enteroendocrine cells': '46.9', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '0.570', 'Excitatory neurons': '7.8', 'Inhibitory neurons': '12.8', 'Cone photoreceptor cells': '37.4', 'Rod photoreceptor cells': '22.9', 'Bipolar cells': '40.5', 'Horizontal cells': '33.4', 'Astrocytes': '5.9', 'Oligodendrocyte precursor cells': '5.7', 'Oligodendrocytes': '27.4', 'Microglial cells': '22.4', 'Muller glia cells': '161.0', 'Schwann cells': '0.203', 'Spermatogonia': '0.605', 'Spermatocytes': '0.208', 'Early spermatids': '-0.390', 'Late spermatids': '-0.600', 'Oocytes': '34.6', 'Cytotrophoblasts': '42.9', 'Syncytiotrophoblasts': '39.3', 'Extravillous trophoblasts': '47.9', 'Endothelial cells': '48.3', 'Lymphatic endothelial cells': '35.6', 'Cardiomyocytes': '0.591', 'Skeletal myocytes': '0.056', 'Smooth muscle cells': '59.7', 'Adipocytes': '59.8', 'Melanocytes': '0.231', 'Fibroblasts': '42.7', 'Peritubular cells': '0.470', 'Endometrial stromal cells': '35.7', 'Ovarian stromal cells': '41.7', 'Undifferentiated cells': '47.6', 'T-cells': '190.6', 'B-cells': '126.4', 'Plasma cells': '104.9', 'Nk-cells': '112.4', 'Granulocytes': '60.0', 'Monocytes': '214.6', 'Macrophages': '64.1', 'Hofbauer cells': '29.4', 'Kupffer cells': '45.2', 'Dendritic cells': '34.0', 'Langerhans cells': '0.223', 'Erythroid cells': '0.094', 'Adipocytes (Subcutaneous)': '-0.517', 'Adipocytes (Visceral)': '-0.477', 'Breast glandular cells (progenitors)': '0.368', 'Adipocytes (Breast)': '-0.627', 'Colon enterocytes': '-0.181', 'Colon enteroendocrine cells': '0.273', 'Enteric glia cells': '0.274', 'Mitotic cells (Colon)': '-0.154', 'Mitotic cells (Heart)': '0.432', 'Podocytes': '0.231', 'Ascending Loop of Henle cells': '0.387', 'Intercalated cells': '0.157', 'Cholangiocyte': '0.289', 'NK-cells (Liver)': '-0.151', 'Respiratory ciliated cells': '0.124', 'Mitotic cells (Lung)': '-0.198', 'NK-cells (Lung)': '0.460', 'B-cells (Lung)': '0.301', 'Alpha cells': '0.322', 'Beta cells': '0.167', 'Prostate glandular cells': '-0.143', 'Prostate basal glandular cells': '-0.077', 'Urothelial cells': '-0.007', 'Keratinocyte (other)': '0.422', 'Keratinocyte (granular)': '-0.212', 'Hair cortex cells': '-0.070', 'Inner root sheath cells': '0.013', 'Outer root sheath cells': '0.228', 'Sebaceous gland cells': '-0.068', 'Eccrine sweat gland cells': '0.016', 'Adipocytes (Skin)': '-0.310', 'Mitotic cells (Skin)': '0.433', 'Parietal cells': '-0.533', 'Chief cells': '-0.430', 'Gastric mucous cells': '-0.374', 'Gastric enteroendocrine cells': '-0.297', 'Mitotic cells (Stomach)': '-0.041', 'Parafollicular cells': '0.037', 'Thyroid glandular cells': '0.270', 'Mitotic cells (Thyroid)': '0.117', 'Adrenal cortex cells': '0.464', 'Adrenal medulla cells': '0.086', 'Mitotic cells (Adrenal gland)': '0.262', 'Minor salivary glandular cells': '0.329', 'Minor salivary gland ductal cells': '0.195', 'Minor salivary gland basal cells': '0.233', 'Mitotic cells (Minor salivary gland)': '0.325', 'Adipocytes (Minor salivary gland)': '0.264', 'Somatotropes': '-0.125', 'Lactotropes': '-0.147', 'Gonadotropes': '0.003', 'Corticotropes': '-0.198', 'Thyrotropes': '0.077', 'Undifferentiated cells (Pituitary gland)': '0.405', 'Mitotic cells (Spleen)': '-0.100', 'Platelets': '-0.172', 'Erythrocytes': '-0.125', 'Hematopoietic stem cells': '-0.154', 'B-cells (Spleen)': '0.316', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '7.2', 'Cerebellar inhibitory': '17.8', 'Cge interneuron': '24.8', 'Deep-layer corticothalamic and 6b': '7.4', 'Deep-layer intratelencephalic': '8.1', 'Deep-layer near-projecting': '6.0', 'Eccentric medium spiny neuron': '7.2', 'Hippocampal ca1-3': '6.8', 'Hippocampal ca4': '7.4', 'Hippocampal dentate gyrus': '7.4', 'Lamp5-lhx6 and chandelier': '21.3', 'Lower rhombic lip': '16.1', 'Mammillary body': '17.5', 'Medium spiny neuron': '7.2', 'Mge interneuron': '18.5', 'Midbrain-derived inhibitory': '21.4', 'Miscellaneous': '8.8', 'Splatter': '14.0', 'Thalamic excitatory': '13.8', 'Upper rhombic lip': '38.3', 'Upper-layer intratelencephalic': '7.4', 'Astrocyte': '10.5', 'Bergmann glia': '20.7', 'Central nervous system macrophage': '22.7', 'Choroid plexus epithelial cell': '13.8', 'Committed oligodendrocyte precursor': '20.0', 'Ependymal cell': '19.3', 'Oligodendrocyte': '39.1', 'Oligodendrocyte precursor cell': '18.7', 'Endothelial cell': '55.0', 'Pericyte': '61.5', 'Vascular associated smooth muscle cell': '58.1', 'Fibroblast': '28.4', 'Leukocyte': '63.4', 'Basophil': '146.3', 'Eosinophil': '8.2', 'Neutrophil': '108.3', 'Classical monocyte': '115.3', 'Non-classical monocyte': '165.4', 'Intermediate monocyte': '55.0', 'T-reg': '96.6', 'GdT-cell': '5.8', 'MAIT T-cell': '112.3', 'Memory CD4 T-cell': '7.5', 'Naive CD4 T-cell': '437.3', 'Memory CD8 T-cell': '6.9', 'Naive CD8 T-cell': '336.0', 'Memory B-cell': '6.7', 'Naive B-cell': '180.8', 'Plasmacytoid DC': '17.6', 'Myeloid DC': '69.7', 'NK-cell': '141.8', 'Total PBMC': '64.5', 'Vd2 gdTCR': '53.3', 'Memory CD4 T-cell Th1\\/Th17': '454.5', 'Memory CD4 T-cell Th17': '375.9', 'Memory CD4 T-cell Th2': '438.1', 'Non-Vd2 gdTCR': '73.3', 'Memory CD4 T-cell Th1': '377.8', 'Memory CD4 T-cell TFH': '436.6', 'Terminal effector memory CD4 T-cell': '50.5', 'Central memory CD8 T-cell': '100.1', 'Effector memory CD8 T-cell': '58.9', 'Terminal effector memory CD8 T-cell': '54.5', 'Non-switched memory B-cell': '46.9', 'Plasmablast': '53.8', 'Switched memory B-cell': '50.0', 'Exhausted memory B-cell': '46.7', 'Progenitor cell': '20.4', 'Memory T-reg': '447.2', 'Naive CD4 T-cell activated': '97.4', 'Naive CD8 T-cell activated': '93.6', 'Naive T-reg': '713.8'}
|
1H27, 1JSU, 2AST, 5UQ3, 6ATH, 6P8E, 6P8F, 6P8G, 7B5L, 7B5M, 7B5R, 7OR8, 7ORG, 7ORH, 7ORS, 7ORT, 8BYA, 8BYL, 8BZO
|
{'Adipose Tissue': 89.28307308970099, 'Adrenal Gland': 49.201007751937986, 'Bladder': 63.78047619047619, 'Blood': 68.55482454251884, 'Blood Vessel': 122.23632958801498, 'Brain': 69.23933762301286, 'Breast': 97.70257080610024, 'Cervix Uteri': 117.59052631578946, 'Colon': 69.30115532734274, 'Esophagus': 56.005737024221446, 'Fallopian Tube': 110.25333333333332, 'Heart': 23.158851335656216, 'Kidney': 27.414337078651688, 'Liver': 24.55152654867257, 'Lung': 82.52216262975779, 'Muscle': 43.84146575342466, 'Nerve': 139.4383198707593, 'Ovary': 106.24844444444444, 'Pancreas': 16.517003048780488, 'Pituitary': 49.177385159010605, 'Prostate': 57.263387755102045, 'Salivary Gland': 48.443765432098765, 'Skin': 63.90882808181316, 'Small Intestine': 65.75898395721926, 'Spleen': 75.991244813278, 'Stomach': 39.69147632311978, 'Testis': 51.55265927977839, 'Thyroid': 78.49858499234303, 'Uterus': 118.09823943661972, 'Vagina': 94.36891025641025}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[48.29, 68.93, 66.41, 74.75, 70.67, 66.43, 66.18, 56.59, 61.92, 59.55, 63.59, 63.42, 62.99, 64.16, 62.97, 61.12, 58.95, 60.2, 59.66, 56.72, 60.4, 70.98, 74.85, 84.62, 87.89, 91.85, 92.87, 95.19, 92.91, 95.02, 95.09, 96.62, 96.97, 95.71, 96.04, 96.77, 96.75, 97.72, 97.44, 97.03, 97.04, 97.42, 97.94, 97.67, 97.19, 96.96, 96.84, 96.37, 94.07, 95.33, 95.63, 94.55, 93.59, 94.76, 95.43, 94.06, 94.0, 93.64, 95.58, 96.11, 94.69, 94.61, 94.06, 92.1, 90.74, 92.39, 92.44, 92.69, 94.65, 92.86, 91.85, 92.07, 94.25, 94.97, 94.89, 95.57, 93.06, 91.38, 92.13, 90.64, 88.87, 89.31, 90.74, 90.09, 93.42, 92.68, 93.13, 92.62, 91.19, 93.1, 92.21, 91.57, 89.31, 85.55, 83.44, 71.71, 63.51, 56.71, 47.22, 55.45, 55.36, 48.19, 50.67, 49.74, 40.28, 51.95, 55.26, 45.66, 56.04, 44.07, 44.88, 45.7, 54.49, 51.23, 45.36, 46.31, 44.06, 48.67, 46.69, 40.62, 43.42, 39.19, 42.9, 48.83, 57.12, 53.02, 53.13, 53.48, 46.54, 51.4, 52.85, 47.94, 47.75, 43.8, 49.24, 54.66, 50.57, 51.6, 51.03, 52.41, 50.53, 51.33, 37.73, 48.48, 46.83, 52.89, 43.6, 44.83, 41.31, 48.53, 53.99, 50.96, 60.43, 67.65, 59.28, 53.83, 61.34, 47.04, 56.3, 48.25, 53.64, 52.16, 49.62, 48.69, 69.04, 44.6, 56.99, 44.54, 62.24, 45.39, 61.18, 62.23, 44.32, 54.33, 44.6, 56.06, 41.21, 54.73, 50.96, 45.35, 49.77, 40.09, 56.35, 59.39, 64.82, 64.01, 67.82, 69.08, 67.9, 71.82, 69.26, 65.6, 65.19, 66.37, 70.91, 69.71, 71.15, 65.53]
|
[1.0, 0.91, 0.95, 0.86, 0.94, 0.9, 0.94, 0.98, 0.79, 0.92, 0.9, 0.82, 0.81, 0.82, 0.84, 0.86, 0.85, 0.83, 0.87, 0.9, 0.72, 0.83, 0.9, 0.85, 0.81, 0.62, 0.69, 0.78, 0.62, 0.68, 0.69, 0.82, 0.98, 0.41, 0.96, 0.6, 0.52, 0.65, 0.74, 0.51, 0.42, 0.47, 0.62, 0.55, 0.54, 0.52, 0.53, 0.59, 0.48, 0.6, 0.4, 0.57, 0.45, 0.41, 0.54, 0.35, 0.3, 0.68, 0.65, 0.47, 0.07, 0.18, 0.18, 0.44, 0.8, 0.64, 0.71, 0.65, 0.59, 0.43, 0.98, 0.68, 0.71, 0.44, 0.85, 0.45, 0.79, 1.0, 0.59, 0.81, 0.62, 0.8, 0.64, 0.45, 0.59, 0.43, 0.81, 0.76, 0.38, 0.62, 0.83, 0.93, 0.92, 0.88, 0.76, 0.95, 0.8, 0.7, 0.8, 0.91, 0.84, 0.79, 0.88, 0.83, 0.84, 0.84, 0.88, 0.99, 1.0, 1.0, 1.0, 0.99, 0.98, 0.97, 0.85, 0.87, 0.8, 0.92, 0.91, 0.93, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.96, 0.97, 0.95, 1.0, 0.99, 0.99, 0.95, 0.97, 0.91, 0.97, 0.93, 0.96, 0.98, 1.0, 0.91, 0.98, 0.81, 0.92, 0.86, 0.88, 0.91, 0.89, 0.94, 0.87, 0.94, 0.91, 0.9, 0.83, 0.86, 0.81, 0.89, 0.99, 0.93, 1.0, 0.99, 0.99, 0.99, 0.91, 1.0, 0.77, 0.95, 1.0, 0.92, 0.99, 0.98, 1.0, 0.99, 1.0, 0.99, 0.99, 0.98, 0.94, 0.86, 0.89, 0.86, 0.84, 0.91, 0.94, 0.96, 0.91, 0.83, 0.93, 0.93, 0.88, 0.97, 0.87, 0.99]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 69.051313
| 0.809899
| 2,742
|
O43255
|
P55036
|
19240029
|
UbiNet, UbiBrowser, 31181401
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
PSMD4
|
MVLESTMVCVDNSEYMRNGDFLPTRLQAQQDAVNIVCHSKTRSNPENNVGLITLANDCEVLTTLTPDTGRILSKLHTVQPKGKITFCTGIRVAHLALKHRQGKNHKMRIIAFVGSPVEDNEKDLVKLAKRLKKEKVNVDIINFGEEEVNTEKLTAFVNTLNGKDGTGSHLVTVPPGPSLADALISSPILAGEGGAMLGLGASDFEFGVDPSADPELALALRVSMEEQRQRQEEEARRAAAASAAEAGIATTGTEDSDDALLKMTISQQEFGRTGLPDLSSMTEEEQIAYAMQMSLQGAEFGQAESADIDASSAMDTSEPAKEEDDYDVMQDPEFLQSVLENLPGVDPNNEAIRNAMGSLASQATKDGKKDKKEEDKK
|
Homo sapiens
| null |
Low tissue specificity
|
{'Ciliated cells': '123.3', 'Basal respiratory cells': '235.1', 'Club cells': '109.3', 'Ionocytes': '149.8', 'Mucus glandular cells': '65.0', 'Serous glandular cells': '82.4', 'Gastric mucus-secreting cells': '51.3', 'Proximal enterocytes': '165.0', 'Paneth cells': '126.8', 'Distal enterocytes': '108.5', 'Intestinal goblet cells': '82.1', 'Exocrine glandular cells': '-0.745', 'Basal prostatic cells': '80.0', 'Prostatic glandular cells': '56.6', 'Breast glandular cells': '0.026', 'Breast myoepithelial cells': '-0.184', 'Glandular and luminal cells': '63.2', 'Secretory cells': '96.5', 'Basal keratinocytes': '97.8', 'Suprabasal keratinocytes': '117.7', 'Basal squamous epithelial cells': '55.2', 'Squamous epithelial cells': '66.2', 'Alveolar cells type 1': '-0.089', 'Alveolar cells type 2': '0.026', 'Salivary duct cells': '63.1', 'Ductal cells': '0.475', 'Hepatocytes': '0.507', 'Cholangiocytes': '83.9', 'Proximal tubular cells': '0.280', 'Distal tubular cells': '132.2', 'Collecting duct cells': '64.2', 'Mesothelial cells': '0.179', 'Sertoli cells': '-0.413', 'Granulosa cells': '86.3', 'Enteroendocrine cells': '88.9', 'Pancreatic endocrine cells': '169.8', 'Leydig cells': '-0.471', 'Excitatory neurons': '24.4', 'Inhibitory neurons': '23.2', 'Cone photoreceptor cells': '71.4', 'Rod photoreceptor cells': '35.6', 'Bipolar cells': '47.2', 'Horizontal cells': '25.2', 'Astrocytes': '14.9', 'Oligodendrocyte precursor cells': '15.1', 'Oligodendrocytes': '21.6', 'Microglial cells': '10.7', 'Muller glia cells': '94.4', 'Schwann cells': '0.052', 'Spermatogonia': '-0.221', 'Spermatocytes': '0.126', 'Early spermatids': '0.738', 'Late spermatids': '0.599', 'Oocytes': '129.4', 'Cytotrophoblasts': '336.6', 'Syncytiotrophoblasts': '437.7', 'Extravillous trophoblasts': '242.8', 'Endothelial cells': '92.6', 'Lymphatic endothelial cells': '76.0', 'Cardiomyocytes': '0.686', 'Skeletal myocytes': '-0.293', 'Smooth muscle cells': '107.5', 'Adipocytes': '85.6', 'Melanocytes': '0.263', 'Fibroblasts': '92.7', 'Peritubular cells': '-0.380', 'Endometrial stromal cells': '65.0', 'Ovarian stromal cells': '120.9', 'Undifferentiated cells': '116.8', 'T-cells': '72.1', 'B-cells': '70.4', 'Plasma cells': '87.8', 'Nk-cells': '83.6', 'Granulocytes': '99.9', 'Monocytes': '104.7', 'Macrophages': '88.2', 'Hofbauer cells': '179.7', 'Kupffer cells': '89.0', 'Dendritic cells': '57.0', 'Langerhans cells': '0.267', 'Erythroid cells': '-0.094', 'Adipocytes (Subcutaneous)': '0.269', 'Adipocytes (Visceral)': '0.098', 'Breast glandular cells (progenitors)': '-0.019', 'Adipocytes (Breast)': '0.231', 'Colon enterocytes': '-0.278', 'Colon enteroendocrine cells': '0.142', 'Enteric glia cells': '-0.056', 'Mitotic cells (Colon)': '-0.302', 'Mitotic cells (Heart)': '0.461', 'Podocytes': '0.023', 'Ascending Loop of Henle cells': '0.383', 'Intercalated cells': '0.034', 'Cholangiocyte': '0.360', 'NK-cells (Liver)': '-0.351', 'Respiratory ciliated cells': '0.018', 'Mitotic cells (Lung)': '0.141', 'NK-cells (Lung)': '-0.184', 'B-cells (Lung)': '-0.263', 'Alpha cells': '0.319', 'Beta cells': '0.150', 'Prostate glandular cells': '-0.240', 'Prostate basal glandular cells': '0.024', 'Urothelial cells': '-0.065', 'Keratinocyte (other)': '0.258', 'Keratinocyte (granular)': '0.073', 'Hair cortex cells': '0.080', 'Inner root sheath cells': '0.140', 'Outer root sheath cells': '0.044', 'Sebaceous gland cells': '-0.063', 'Eccrine sweat gland cells': '-0.231', 'Adipocytes (Skin)': '-0.106', 'Mitotic cells (Skin)': '0.283', 'Parietal cells': '-0.658', 'Chief cells': '-0.495', 'Gastric mucous cells': '-0.411', 'Gastric enteroendocrine cells': '-0.454', 'Mitotic cells (Stomach)': '0.044', 'Parafollicular cells': '0.065', 'Thyroid glandular cells': '0.311', 'Mitotic cells (Thyroid)': '-0.043', 'Adrenal cortex cells': '0.428', 'Adrenal medulla cells': '0.014', 'Mitotic cells (Adrenal gland)': '0.388', 'Minor salivary glandular cells': '0.386', 'Minor salivary gland ductal cells': '-0.241', 'Minor salivary gland basal cells': '0.444', 'Mitotic cells (Minor salivary gland)': '0.625', 'Adipocytes (Minor salivary gland)': '0.260', 'Somatotropes': '0.022', 'Lactotropes': '-0.048', 'Gonadotropes': '-0.016', 'Corticotropes': '-0.129', 'Thyrotropes': '0.172', 'Undifferentiated cells (Pituitary gland)': '0.212', 'Mitotic cells (Spleen)': '-0.214', 'Platelets': '-0.075', 'Erythrocytes': '-0.097', 'Hematopoietic stem cells': '-0.071', 'B-cells (Spleen)': '0.197', 'NK-cells (Spleen)': '0.054', 'Amygdala excitatory': '37.5', 'Cerebellar inhibitory': '37.3', 'Cge interneuron': '38.4', 'Deep-layer corticothalamic and 6b': '45.3', 'Deep-layer intratelencephalic': '45.8', 'Deep-layer near-projecting': '47.4', 'Eccentric medium spiny neuron': '34.8', 'Hippocampal ca1-3': '43.1', 'Hippocampal ca4': '55.8', 'Hippocampal dentate gyrus': '40.8', 'Lamp5-lhx6 and chandelier': '40.2', 'Lower rhombic lip': '66.2', 'Mammillary body': '38.5', 'Medium spiny neuron': '33.8', 'Mge interneuron': '43.4', 'Midbrain-derived inhibitory': '41.3', 'Miscellaneous': '42.1', 'Splatter': '41.6', 'Thalamic excitatory': '49.2', 'Upper rhombic lip': '36.8', 'Upper-layer intratelencephalic': '41.1', 'Astrocyte': '27.9', 'Bergmann glia': '24.6', 'Central nervous system macrophage': '34.7', 'Choroid plexus epithelial cell': '30.8', 'Committed oligodendrocyte precursor': '32.2', 'Ependymal cell': '33.2', 'Oligodendrocyte': '39.1', 'Oligodendrocyte precursor cell': '28.9', 'Endothelial cell': '33.4', 'Pericyte': '41.8', 'Vascular associated smooth muscle cell': '45.6', 'Fibroblast': '28.7', 'Leukocyte': '34.6', 'Basophil': '221.1', 'Eosinophil': '715.7', 'Neutrophil': '401.8', 'Classical monocyte': '80.2', 'Non-classical monocyte': '103.0', 'Intermediate monocyte': '319.7', 'T-reg': '206.3', 'GdT-cell': '247.9', 'MAIT T-cell': '185.8', 'Memory CD4 T-cell': '288.2', 'Naive CD4 T-cell': '59.7', 'Memory CD8 T-cell': '274.5', 'Naive CD8 T-cell': '58.7', 'Memory B-cell': '400.6', 'Naive B-cell': '44.5', 'Plasmacytoid DC': '238.7', 'Myeloid DC': '268.4', 'NK-cell': '79.3', 'Total PBMC': '288.6', 'Vd2 gdTCR': '203.5', 'Memory CD4 T-cell Th1\\/Th17': '61.3', 'Memory CD4 T-cell Th17': '74.8', 'Memory CD4 T-cell Th2': '70.2', 'Non-Vd2 gdTCR': '202.1', 'Memory CD4 T-cell Th1': '72.3', 'Memory CD4 T-cell TFH': '81.4', 'Terminal effector memory CD4 T-cell': '169.6', 'Central memory CD8 T-cell': '167.0', 'Effector memory CD8 T-cell': '215.4', 'Terminal effector memory CD8 T-cell': '201.9', 'Non-switched memory B-cell': '232.4', 'Plasmablast': '330.3', 'Switched memory B-cell': '242.4', 'Exhausted memory B-cell': '206.9', 'Progenitor cell': '170.6', 'Memory T-reg': '101.8', 'Naive CD4 T-cell activated': '89.2', 'Naive CD8 T-cell activated': '109.6', 'Naive T-reg': '65.3'}
|
1P9C, 1P9D, 1UEL, 1YX4, 1YX5, 1YX6, 2KDE, 2KDF, 5GJQ, 5GJR, 5L4K, 5LN3, 5M32, 5T0C, 5T0G, 5T0H, 5T0I, 5T0J, 5VFP, 5VFQ, 5VFR, 5VFS, 5VFT, 5VFU, 5VGZ, 5VHF, 5VHH, 5VHI, 5VHS, 6MSB, 6MSD, 6MSE, 6MSG, 6MSH, 6MSJ, 6MSK, 6MUN, 6U19, 6WJD, 6WJN, 7QXN, 7QXP, 7QXU, 7QXW, 7QXX, 7QY7, 7QYA, 7QYB, 7W37, 7W38, 7W39, 7W3A, 7W3B, 7W3C, 7W3F, 7W3G, 7W3H, 7W3I, 7W3J, 7W3K, 7W3M, 8CVT
|
{'Adipose Tissue': 130.58397009966777, 'Adrenal Gland': 112.06674418604652, 'Bladder': 161.34428571428572, 'Blood': 126.73810548977394, 'Blood Vessel': 178.44722097378278, 'Brain': 112.51081377744131, 'Breast': 127.58614379084968, 'Cervix Uteri': 142.29999999999998, 'Colon': 142.35978177150193, 'Esophagus': 144.21247750865052, 'Fallopian Tube': 150.96666666666667, 'Heart': 80.91817421602786, 'Kidney': 76.30786516853932, 'Liver': 73.51946902654868, 'Lung': 124.86148788927336, 'Muscle': 230.68657534246577, 'Nerve': 157.01793214862684, 'Ovary': 133.57011111111112, 'Pancreas': 49.08298780487805, 'Pituitary': 104.81685512367493, 'Prostate': 122.1535918367347, 'Salivary Gland': 92.65753086419754, 'Skin': 135.96165284687672, 'Small Intestine': 108.37374331550802, 'Spleen': 133.20697095435685, 'Stomach': 106.43529247910864, 'Testis': 233.95706371191136, 'Thyroid': 121.93591117917305, 'Uterus': 160.2387323943662, 'Vagina': 125.9401282051282}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[60.25, 77.78, 85.32, 87.12, 90.21, 90.45, 92.62, 92.77, 91.66, 90.82, 89.86, 87.52, 87.94, 85.22, 84.18, 84.81, 82.81, 81.81, 76.13, 81.27, 76.92, 75.69, 77.26, 83.78, 86.6, 85.29, 87.2, 86.27, 87.24, 88.95, 88.61, 87.08, 88.95, 88.94, 87.49, 87.13, 85.55, 86.43, 85.35, 85.44, 84.51, 85.65, 85.3, 85.71, 85.75, 86.1, 89.04, 89.52, 90.11, 91.63, 92.11, 92.64, 90.5, 87.98, 81.51, 74.16, 75.68, 77.89, 83.93, 87.45, 87.28, 89.52, 89.06, 88.98, 88.6, 86.54, 88.71, 86.83, 89.43, 89.24, 89.38, 87.9, 90.46, 89.33, 87.39, 87.75, 87.99, 87.06, 84.78, 85.81, 84.15, 83.29, 84.36, 83.65, 85.93, 86.69, 88.09, 88.89, 89.72, 90.91, 90.16, 91.41, 90.95, 88.05, 88.91, 87.53, 85.94, 83.97, 81.25, 77.7, 72.43, 75.72, 79.3, 82.9, 84.12, 86.95, 89.63, 90.42, 92.84, 92.11, 91.49, 90.18, 88.41, 84.99, 84.49, 84.35, 83.09, 80.83, 82.49, 88.22, 85.91, 88.78, 90.35, 88.98, 90.47, 90.98, 89.81, 89.83, 90.42, 89.59, 89.22, 85.77, 87.63, 87.67, 85.45, 88.23, 89.22, 90.63, 90.85, 89.9, 88.27, 86.71, 82.3, 75.36, 72.41, 69.26, 69.62, 75.47, 79.49, 81.25, 85.32, 86.63, 86.6, 86.98, 87.55, 88.04, 87.3, 87.35, 86.05, 85.51, 82.38, 76.15, 62.85, 60.89, 58.4, 64.9, 71.11, 79.94, 85.2, 85.62, 85.41, 83.94, 82.59, 82.19, 77.4, 76.06, 69.21, 68.81, 69.83, 68.52, 71.93, 68.95, 69.88, 70.68, 58.84, 64.86, 57.61, 60.05, 61.08, 54.03, 49.45, 56.24, 36.07, 36.12, 38.31, 36.82, 44.87, 32.68, 41.28, 32.76, 40.61, 47.39, 54.84, 56.05, 63.55, 64.0, 66.98, 70.93, 74.22, 74.92, 78.4, 79.48, 84.75, 85.23, 86.79, 86.38, 85.99, 84.58, 89.62, 87.19, 87.67, 89.12, 89.77, 87.51, 88.24, 91.29, 89.27, 89.65, 90.12, 87.76, 89.68, 90.46, 89.07, 89.73, 88.14, 86.54, 86.7, 85.42, 84.08, 84.87, 82.7, 76.91, 76.24, 72.92, 59.42, 59.32, 46.53, 39.35, 35.04, 31.11, 30.55, 31.11, 32.51, 40.14, 43.6, 46.78, 49.12, 51.82, 52.08, 62.5, 59.31, 55.3, 53.15, 49.65, 51.55, 45.94, 44.1, 39.27, 37.84, 31.62, 30.84, 29.57, 38.08, 46.28, 52.6, 57.82, 58.42, 63.34, 65.8, 60.31, 72.98, 80.23, 75.01, 80.95, 80.82, 82.06, 78.55, 80.9, 81.37, 80.22, 83.53, 81.13, 78.62, 79.04, 79.29, 66.25, 52.39, 50.85, 42.69, 33.92, 31.24, 33.57, 27.74, 27.69, 27.91, 30.05, 27.59, 34.44, 27.6, 29.01, 27.91, 34.8, 30.36, 35.99, 25.09, 38.52, 34.67, 29.18, 32.4, 32.84, 32.56, 34.75, 35.48, 40.95, 42.64, 53.01, 63.73, 61.04, 64.96, 65.98, 76.8, 72.86, 75.56, 79.13, 77.41, 73.81, 80.04, 80.9, 72.18, 80.22, 84.16, 75.09, 73.74, 74.69, 80.64, 76.34, 73.11, 72.7, 83.49, 82.37, 78.24, 77.1, 78.69, 79.59, 76.21, 76.25, 77.71, 76.23, 70.86, 71.08, 66.5, 62.75, 56.81, 53.9, 50.71, 48.46, 42.57, 41.18, 39.2, 40.9, 43.2, 41.37, 43.6, 43.44, 43.84, 42.92, 45.85]
|
[0.88, 0.28, 0.28, 0.02, 0.01, 0.01, 0.0, 0.01, 0.01, 0.01, 0.0, 0.09, 0.01, 0.53, 0.43, 0.01, 0.62, 0.38, 0.67, 0.37, 0.0, 0.66, 0.74, 0.43, 0.05, 0.14, 0.35, 0.07, 0.03, 0.09, 0.43, 0.0, 0.01, 0.29, 0.26, 0.02, 0.02, 0.51, 0.32, 0.03, 0.33, 0.89, 0.42, 0.06, 0.74, 0.63, 0.01, 0.18, 0.04, 0.01, 0.0, 0.0, 0.07, 0.01, 0.11, 0.56, 0.72, 0.16, 0.58, 0.4, 0.34, 0.05, 0.8, 0.23, 0.17, 0.52, 0.46, 0.24, 0.4, 0.6, 0.02, 0.29, 0.57, 0.47, 0.03, 0.64, 0.69, 0.11, 0.63, 0.19, 0.57, 0.24, 0.68, 0.17, 0.31, 0.01, 0.08, 0.33, 0.0, 0.03, 0.51, 0.26, 0.0, 0.14, 0.56, 0.16, 0.0, 0.57, 0.79, 0.26, 0.92, 0.28, 0.87, 0.83, 0.12, 0.56, 0.13, 0.1, 0.0, 0.0, 0.01, 0.02, 0.0, 0.0, 0.01, 0.31, 0.07, 0.79, 0.24, 0.63, 0.61, 0.79, 0.36, 0.04, 0.25, 0.55, 0.08, 0.0, 0.6, 0.61, 0.02, 0.39, 0.85, 0.32, 0.8, 0.02, 0.3, 0.01, 0.0, 0.0, 0.02, 0.01, 0.02, 0.27, 0.4, 0.46, 0.84, 0.58, 0.01, 0.2, 0.77, 0.3, 0.01, 0.39, 0.25, 0.01, 0.08, 0.61, 0.34, 0.11, 0.25, 0.66, 0.92, 0.87, 0.54, 0.72, 0.19, 0.05, 0.23, 0.31, 0.1, 0.33, 0.08, 0.73, 0.69, 0.29, 0.68, 0.48, 0.04, 0.23, 0.57, 0.3, 0.02, 0.37, 0.55, 0.06, 0.42, 0.04, 0.16, 0.23, 0.73, 0.24, 0.47, 0.95, 0.75, 0.63, 0.78, 0.48, 0.94, 0.59, 0.91, 0.94, 0.95, 0.59, 0.87, 0.57, 0.77, 0.23, 0.46, 0.46, 0.8, 0.77, 0.42, 0.54, 0.79, 0.44, 0.13, 0.59, 0.46, 0.2, 0.59, 0.59, 0.45, 0.5, 0.52, 0.64, 0.53, 0.57, 0.5, 0.72, 0.66, 0.54, 0.69, 0.69, 0.51, 0.78, 0.79, 0.47, 0.53, 0.54, 0.48, 0.54, 0.59, 0.46, 0.77, 0.74, 0.7, 0.81, 0.88, 0.94, 0.99, 0.94, 0.79, 1.0, 0.8, 0.55, 0.78, 0.71, 0.45, 0.68, 0.64, 0.69, 0.61, 0.62, 0.67, 0.48, 0.79, 0.51, 0.81, 0.87, 0.82, 0.9, 0.87, 0.92, 0.77, 0.38, 0.43, 0.48, 0.63, 0.78, 0.34, 0.61, 0.74, 0.77, 0.48, 0.39, 0.59, 0.56, 0.2, 0.49, 0.67, 0.61, 0.58, 0.69, 0.7, 0.65, 0.69, 0.7, 0.75, 0.94, 0.78, 0.88, 0.92, 0.99, 1.0, 1.0, 0.98, 0.98, 0.99, 0.97, 0.97, 0.95, 0.99, 0.93, 0.96, 0.97, 0.84, 0.98, 0.94, 0.92, 0.82, 0.92, 0.8, 0.8, 0.85, 0.82, 0.67, 0.46, 0.67, 0.57, 0.55, 0.47, 0.81, 0.45, 0.28, 0.54, 0.4, 0.41, 0.25, 0.77, 0.76, 0.48, 0.89, 0.89, 0.31, 0.66, 0.52, 0.79, 0.48, 0.7, 0.61, 0.21, 0.67, 0.57, 0.5, 0.36, 0.43, 0.49, 0.48, 0.47, 0.45, 0.63, 0.45, 0.63, 0.83, 0.7, 0.54, 0.78, 0.84, 0.82, 0.87, 0.88, 0.92, 0.9, 0.94, 0.96, 0.98]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 72.068806
| 0.487294
| 2,061
|
O43255
|
Q12933
|
12411493
|
UbiBrowser
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
TRAF2
|
MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
|
Homo sapiens
|
Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '6.0', 'Basal respiratory cells': '17.8', 'Club cells': '8.8', 'Ionocytes': '16.9', 'Mucus glandular cells': '6.7', 'Serous glandular cells': '4.6', 'Gastric mucus-secreting cells': '9.4', 'Proximal enterocytes': '13.7', 'Paneth cells': '13.8', 'Distal enterocytes': '17.8', 'Intestinal goblet cells': '17.0', 'Exocrine glandular cells': '-0.654', 'Basal prostatic cells': '4.5', 'Prostatic glandular cells': '7.1', 'Breast glandular cells': '0.549', 'Breast myoepithelial cells': '0.617', 'Glandular and luminal cells': '5.8', 'Secretory cells': '7.7', 'Basal keratinocytes': '10.0', 'Suprabasal keratinocytes': '9.6', 'Basal squamous epithelial cells': '4.2', 'Squamous epithelial cells': '5.1', 'Alveolar cells type 1': '0.040', 'Alveolar cells type 2': '-0.475', 'Salivary duct cells': '4.1', 'Ductal cells': '0.685', 'Hepatocytes': '-0.033', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.158', 'Distal tubular cells': '0.0', 'Collecting duct cells': '7.8', 'Mesothelial cells': '0.335', 'Sertoli cells': '0.189', 'Granulosa cells': '6.2', 'Enteroendocrine cells': '9.2', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.078', 'Excitatory neurons': '5.4', 'Inhibitory neurons': '4.3', 'Cone photoreceptor cells': '3.4', 'Rod photoreceptor cells': '8.4', 'Bipolar cells': '7.8', 'Horizontal cells': '12.6', 'Astrocytes': '7.1', 'Oligodendrocyte precursor cells': '2.4', 'Oligodendrocytes': '5.3', 'Microglial cells': '2.7', 'Muller glia cells': '4.4', 'Schwann cells': '0.071', 'Spermatogonia': '0.229', 'Spermatocytes': '0.222', 'Early spermatids': '-0.226', 'Late spermatids': '-0.165', 'Oocytes': '58.8', 'Cytotrophoblasts': '20.6', 'Syncytiotrophoblasts': '19.2', 'Extravillous trophoblasts': '30.4', 'Endothelial cells': '8.4', 'Lymphatic endothelial cells': '4.5', 'Cardiomyocytes': '0.332', 'Skeletal myocytes': '0.007', 'Smooth muscle cells': '6.0', 'Adipocytes': '8.1', 'Melanocytes': '0.180', 'Fibroblasts': '5.6', 'Peritubular cells': '0.112', 'Endometrial stromal cells': '4.3', 'Ovarian stromal cells': '5.7', 'Undifferentiated cells': '15.8', 'T-cells': '11.3', 'B-cells': '10.7', 'Plasma cells': '12.9', 'Nk-cells': '8.7', 'Granulocytes': '6.5', 'Monocytes': '2.2', 'Macrophages': '5.8', 'Hofbauer cells': '10.9', 'Kupffer cells': '1.7', 'Dendritic cells': '3.8', 'Langerhans cells': '0.380', 'Erythroid cells': '0.103', 'Adipocytes (Subcutaneous)': '-0.538', 'Adipocytes (Visceral)': '-0.446', 'Breast glandular cells (progenitors)': '0.387', 'Adipocytes (Breast)': '-0.718', 'Colon enterocytes': '-0.008', 'Colon enteroendocrine cells': '0.040', 'Enteric glia cells': '0.452', 'Mitotic cells (Colon)': '0.063', 'Mitotic cells (Heart)': '0.448', 'Podocytes': '-0.038', 'Ascending Loop of Henle cells': '0.363', 'Intercalated cells': '-0.017', 'Cholangiocyte': '0.248', 'NK-cells (Liver)': '-0.148', 'Respiratory ciliated cells': '0.077', 'Mitotic cells (Lung)': '0.022', 'NK-cells (Lung)': '0.371', 'B-cells (Lung)': '0.203', 'Alpha cells': '0.441', 'Beta cells': '0.293', 'Prostate glandular cells': '0.066', 'Prostate basal glandular cells': '0.380', 'Urothelial cells': '0.484', 'Keratinocyte (other)': '0.517', 'Keratinocyte (granular)': '-0.248', 'Hair cortex cells': '-0.229', 'Inner root sheath cells': '-0.177', 'Outer root sheath cells': '0.062', 'Sebaceous gland cells': '-0.080', 'Eccrine sweat gland cells': '-0.195', 'Adipocytes (Skin)': '-0.445', 'Mitotic cells (Skin)': '0.330', 'Parietal cells': '-0.238', 'Chief cells': '-0.127', 'Gastric mucous cells': '0.176', 'Gastric enteroendocrine cells': '0.071', 'Mitotic cells (Stomach)': '0.346', 'Parafollicular cells': '0.065', 'Thyroid glandular cells': '0.318', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.330', 'Adrenal medulla cells': '-0.034', 'Mitotic cells (Adrenal gland)': '0.062', 'Minor salivary glandular cells': '0.512', 'Minor salivary gland ductal cells': '-0.006', 'Minor salivary gland basal cells': '0.279', 'Mitotic cells (Minor salivary gland)': '0.393', 'Adipocytes (Minor salivary gland)': '0.086', 'Somatotropes': '0.058', 'Lactotropes': '0.316', 'Gonadotropes': '0.200', 'Corticotropes': '-0.024', 'Thyrotropes': '0.170', 'Undifferentiated cells (Pituitary gland)': '0.049', 'Mitotic cells (Spleen)': '-0.047', 'Platelets': '-0.255', 'Erythrocytes': '0.014', 'Hematopoietic stem cells': '-0.306', 'B-cells (Spleen)': '0.360', 'NK-cells (Spleen)': '0.204', 'Amygdala excitatory': '8.1', 'Cerebellar inhibitory': '8.1', 'Cge interneuron': '4.8', 'Deep-layer corticothalamic and 6b': '10.9', 'Deep-layer intratelencephalic': '8.5', 'Deep-layer near-projecting': '14.9', 'Eccentric medium spiny neuron': '8.2', 'Hippocampal ca1-3': '10.9', 'Hippocampal ca4': '9.0', 'Hippocampal dentate gyrus': '7.9', 'Lamp5-lhx6 and chandelier': '7.0', 'Lower rhombic lip': '10.8', 'Mammillary body': '7.9', 'Medium spiny neuron': '15.3', 'Mge interneuron': '8.7', 'Midbrain-derived inhibitory': '4.4', 'Miscellaneous': '12.2', 'Splatter': '7.8', 'Thalamic excitatory': '9.0', 'Upper rhombic lip': '10.8', 'Upper-layer intratelencephalic': '7.8', 'Astrocyte': '14.2', 'Bergmann glia': '8.7', 'Central nervous system macrophage': '10.5', 'Choroid plexus epithelial cell': '6.4', 'Committed oligodendrocyte precursor': '6.9', 'Ependymal cell': '7.4', 'Oligodendrocyte': '8.9', 'Oligodendrocyte precursor cell': '6.4', 'Endothelial cell': '9.3', 'Pericyte': '8.3', 'Vascular associated smooth muscle cell': '10.3', 'Fibroblast': '6.9', 'Leukocyte': '17.1', 'Basophil': '26.9', 'Eosinophil': '9.1', 'Neutrophil': '23.1', 'Classical monocyte': '3.6', 'Non-classical monocyte': '5.3', 'Intermediate monocyte': '20.3', 'T-reg': '44.1', 'GdT-cell': '12.3', 'MAIT T-cell': '44.9', 'Memory CD4 T-cell': '13.4', 'Naive CD4 T-cell': '9.7', 'Memory CD8 T-cell': '15.6', 'Naive CD8 T-cell': '13.9', 'Memory B-cell': '15.3', 'Naive B-cell': '12.6', 'Plasmacytoid DC': '58.1', 'Myeloid DC': '20.2', 'NK-cell': '15.2', 'Total PBMC': '31.1', 'Vd2 gdTCR': '40.5', 'Memory CD4 T-cell Th1\\/Th17': '13.4', 'Memory CD4 T-cell Th17': '17.5', 'Memory CD4 T-cell Th2': '19.1', 'Non-Vd2 gdTCR': '53.3', 'Memory CD4 T-cell Th1': '22.1', 'Memory CD4 T-cell TFH': '27.7', 'Terminal effector memory CD4 T-cell': '48.9', 'Central memory CD8 T-cell': '44.2', 'Effector memory CD8 T-cell': '58.9', 'Terminal effector memory CD8 T-cell': '41.6', 'Non-switched memory B-cell': '57.4', 'Plasmablast': '64.0', 'Switched memory B-cell': '55.5', 'Exhausted memory B-cell': '48.9', 'Progenitor cell': '37.4', 'Memory T-reg': '26.3', 'Naive CD4 T-cell activated': '44.9', 'Naive CD8 T-cell activated': '44.6', 'Naive T-reg': '17.4'}
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1CA4, 1CA9, 1CZY, 1CZZ, 1D00, 1D01, 1D0A, 1D0J, 1F3V, 1QSC, 3KNV, 3M06, 3M0A, 3M0D, 8T5Q
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{'Adipose Tissue': 9.683515780730897, 'Adrenal Gland': 7.438957364341086, 'Bladder': 12.681428571428572, 'Blood': 10.631841657696448, 'Blood Vessel': 11.77251086142322, 'Brain': 9.261735881907644, 'Breast': 11.760389978213508, 'Cervix Uteri': 15.06, 'Colon': 10.49494351732991, 'Esophagus': 11.246509342560554, 'Fallopian Tube': 12.088111111111113, 'Heart': 4.309772241579559, 'Kidney': 7.742191011235954, 'Liver': 7.33796017699115, 'Lung': 13.690420415224914, 'Muscle': 4.5295828144458286, 'Nerve': 13.11303392568659, 'Ovary': 9.936166666666669, 'Pancreas': 3.826545731707317, 'Pituitary': 13.49859363957597, 'Prostate': 16.426436734693876, 'Salivary Gland': 12.144358024691355, 'Skin': 13.567098949695966, 'Small Intestine': 13.506320855614971, 'Spleen': 19.458547717842325, 'Stomach': 7.588961002785515, 'Testis': 25.925404432132964, 'Thyroid': 21.32201531393568, 'Uterus': 13.27369718309859, 'Vagina': 15.411467948717949}
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[33.66, 35.52, 33.16, 36.45, 34.63, 30.97, 36.6, 29.78, 35.14, 33.08, 40.14, 37.65, 45.79, 53.27, 67.24, 83.79, 90.45, 94.19, 94.73, 93.47, 93.98, 92.28, 93.83, 92.58, 86.56, 88.7, 89.71, 89.5, 93.04, 92.16, 94.04, 95.72, 96.62, 97.54, 96.95, 95.79, 95.89, 95.62, 96.6, 96.72, 96.96, 95.54, 94.18, 96.09, 96.87, 97.32, 96.28, 95.3, 95.94, 95.31, 97.54, 97.5, 97.11, 96.54, 94.9, 94.74, 96.01, 95.26, 93.64, 94.25, 94.79, 94.07, 92.62, 89.91, 91.13, 94.03, 95.56, 95.66, 97.27, 96.09, 96.03, 97.69, 96.36, 95.03, 95.87, 95.35, 96.32, 96.51, 94.77, 92.55, 90.2, 94.01, 96.65, 96.0, 95.58, 92.96, 89.61, 90.35, 92.14, 94.26, 96.02, 96.51, 97.13, 95.07, 95.84, 95.79, 96.53, 96.61, 95.98, 96.25, 96.08, 95.84, 96.64, 97.2, 96.67, 96.33, 95.09, 92.45, 92.68, 91.66, 91.72, 95.01, 95.38, 96.72, 96.2, 96.75, 96.91, 95.86, 95.36, 96.12, 95.26, 92.94, 91.8, 91.92, 93.92, 92.68, 89.72, 92.09, 94.12, 93.41, 95.38, 93.93, 94.2, 93.1, 93.09, 90.68, 87.49, 82.16, 86.87, 90.09, 92.39, 94.42, 94.27, 94.9, 93.72, 91.92, 93.39, 92.75, 90.53, 92.31, 93.13, 87.38, 84.83, 86.24, 85.86, 87.71, 80.33, 78.34, 80.64, 73.11, 72.4, 79.35, 82.76, 84.33, 88.17, 87.45, 84.25, 80.54, 76.76, 72.32, 69.85, 67.64, 67.27, 74.19, 77.44, 82.17, 81.78, 85.34, 89.03, 88.48, 86.86, 88.46, 90.56, 91.79, 92.89, 93.62, 93.26, 92.6, 91.3, 87.21, 82.83, 88.5, 87.34, 88.91, 90.38, 90.71, 91.28, 93.04, 93.61, 92.43, 91.81, 91.07, 87.4, 87.51, 89.69, 85.79, 82.05, 81.28, 85.87, 81.83, 86.52, 85.13, 85.1, 83.77, 88.68, 89.95, 86.78, 90.47, 89.71, 84.12, 84.48, 85.32, 90.62, 88.89, 88.85, 88.29, 87.4, 85.72, 81.75, 85.28, 88.05, 86.93, 88.17, 90.38, 92.35, 89.37, 90.81, 90.97, 90.81, 91.52, 90.85, 90.59, 92.24, 88.61, 87.83, 88.69, 86.08, 83.1, 82.93, 79.66, 75.67, 71.77, 64.12, 61.18, 41.07, 43.71, 38.19, 48.47, 45.23, 43.64, 48.08, 55.0, 55.18, 60.57, 68.52, 77.1, 79.06, 80.58, 83.18, 86.0, 88.65, 88.76, 91.24, 92.74, 92.25, 91.95, 93.86, 94.49, 92.42, 94.21, 95.42, 95.05, 93.4, 94.26, 96.21, 95.91, 95.17, 97.02, 95.81, 94.72, 95.55, 95.95, 96.67, 95.07, 96.15, 95.59, 95.47, 95.68, 96.06, 95.67, 96.16, 96.1, 96.55, 96.1, 96.79, 96.49, 96.84, 96.78, 97.17, 96.65, 96.45, 96.72, 97.4, 97.46, 96.62, 97.25, 98.14, 97.44, 97.01, 97.88, 98.26, 96.93, 97.47, 97.99, 97.06, 96.38, 97.27, 97.95, 95.57, 95.62, 96.99, 95.95, 94.38, 96.57, 96.93, 95.36, 95.66, 96.92, 95.98, 91.83, 92.21, 95.35, 91.04, 89.15, 90.86, 92.33, 92.06, 93.65, 96.92, 96.7, 96.83, 96.91, 98.12, 98.07, 97.79, 97.38, 96.64, 96.73, 96.11, 96.91, 95.72, 94.74, 97.37, 97.81, 95.66, 96.74, 97.82, 97.11, 96.24, 96.73, 94.38, 96.5, 96.42, 95.3, 97.27, 97.31, 97.19, 96.86, 95.75, 96.41, 97.73, 98.01, 97.55, 96.31, 95.11, 96.28, 97.24, 98.07, 97.96, 97.95, 97.85, 98.43, 98.39, 98.44, 98.22, 97.06, 96.79, 96.93, 96.53, 94.92, 96.28, 95.38, 95.97, 95.4, 96.61, 97.75, 97.01, 98.33, 98.3, 98.13, 98.26, 98.48, 98.21, 98.14, 98.1, 96.33, 95.49, 96.3, 97.54, 96.49, 95.86, 96.49, 95.89, 96.73, 96.98, 97.18, 96.08, 96.88, 97.63, 98.18, 98.36, 98.44, 97.91, 97.35, 97.24, 95.33, 94.8, 93.43, 90.85, 91.59, 93.6, 95.93, 96.6, 97.26, 97.21, 97.12, 96.37, 94.99, 95.6, 94.76, 94.45, 96.34, 97.01, 96.7, 97.23, 97.94, 97.97, 97.95, 97.14, 95.77, 95.94, 96.72, 97.32, 97.62, 96.49, 96.89, 96.52, 94.23, 95.49, 96.53, 97.36, 97.62, 96.51, 96.25, 93.31, 92.67, 92.05, 88.51, 82.88, 81.21, 75.72, 79.38, 91.52, 95.13, 93.89, 93.13, 92.93, 94.69, 96.39, 96.78, 97.59, 98.14, 98.24, 98.44, 98.26, 98.17, 97.13, 95.42, 92.29, 85.04, 84.86]
|
[0.93, 0.96, 0.85, 0.82, 0.82, 0.86, 0.76, 0.87, 0.93, 0.89, 0.55, 0.92, 0.97, 0.67, 0.59, 0.36, 0.52, 0.11, 0.05, 0.45, 0.42, 0.59, 0.03, 0.12, 0.54, 0.45, 0.9, 0.41, 0.5, 0.71, 0.54, 0.11, 0.21, 0.01, 0.22, 0.44, 0.33, 0.54, 0.29, 0.0, 0.01, 0.06, 0.43, 0.05, 0.23, 0.24, 0.05, 0.51, 0.2, 0.4, 0.11, 0.26, 0.03, 0.0, 0.24, 0.37, 0.09, 0.05, 0.48, 0.55, 0.31, 0.15, 0.73, 0.85, 0.36, 0.65, 0.43, 0.56, 0.0, 0.46, 0.07, 0.01, 0.58, 0.78, 0.59, 0.74, 0.49, 0.41, 0.58, 0.86, 0.52, 0.4, 0.01, 0.25, 0.02, 0.34, 0.71, 0.8, 0.22, 0.14, 0.53, 0.58, 0.05, 0.44, 0.46, 0.02, 0.36, 0.71, 0.39, 0.03, 0.29, 0.61, 0.11, 0.41, 0.02, 0.32, 0.11, 0.46, 0.16, 0.83, 0.71, 0.23, 0.83, 0.25, 0.8, 0.27, 0.26, 0.02, 0.58, 0.47, 0.06, 0.3, 0.67, 0.72, 0.13, 0.25, 0.51, 0.71, 0.01, 0.53, 0.32, 0.28, 0.61, 0.27, 0.54, 0.01, 0.56, 0.44, 0.33, 0.63, 0.31, 0.71, 0.13, 0.43, 0.27, 0.62, 0.34, 0.27, 0.63, 0.48, 0.11, 0.34, 0.75, 0.76, 0.5, 0.0, 0.5, 0.5, 0.31, 0.83, 0.33, 0.75, 0.03, 0.86, 0.33, 0.27, 0.82, 0.36, 0.81, 0.14, 0.22, 0.3, 0.66, 0.55, 0.24, 0.79, 0.53, 0.21, 0.19, 0.7, 0.72, 0.01, 0.41, 0.52, 0.24, 0.43, 0.23, 0.48, 0.03, 0.91, 0.4, 0.35, 0.47, 0.59, 0.77, 0.82, 0.07, 0.36, 0.31, 0.59, 0.64, 0.24, 0.71, 0.58, 0.15, 0.38, 0.79, 0.77, 0.1, 0.15, 0.51, 0.09, 0.69, 0.38, 0.64, 0.04, 0.69, 0.24, 0.46, 0.93, 0.29, 0.5, 0.05, 0.77, 0.45, 0.37, 0.13, 0.37, 0.34, 0.63, 0.47, 0.13, 0.71, 0.62, 0.08, 0.14, 0.74, 0.83, 0.47, 0.5, 0.86, 0.44, 0.01, 0.54, 0.5, 0.22, 0.35, 0.55, 0.39, 0.37, 0.54, 0.57, 0.63, 0.7, 0.79, 0.86, 0.77, 0.91, 0.86, 0.86, 0.76, 0.64, 0.84, 0.54, 0.29, 0.42, 0.51, 0.58, 0.61, 0.64, 0.61, 0.47, 0.51, 0.41, 0.58, 0.63, 0.65, 0.56, 0.48, 0.41, 0.51, 0.61, 0.66, 0.63, 0.47, 0.6, 0.43, 0.64, 0.58, 0.49, 0.67, 0.48, 0.64, 0.52, 0.53, 0.54, 0.44, 0.63, 0.48, 0.49, 0.69, 0.45, 0.62, 0.48, 0.68, 0.48, 0.55, 0.69, 0.46, 0.36, 0.45, 0.58, 0.58, 0.64, 0.67, 0.56, 0.64, 0.45, 0.52, 0.53, 0.49, 0.54, 0.5, 0.54, 0.59, 0.67, 0.37, 0.57, 0.39, 0.64, 0.59, 0.47, 0.66, 0.44, 0.51, 0.49, 0.5, 0.57, 0.62, 0.51, 0.48, 0.45, 0.58, 0.48, 0.64, 0.72, 0.28, 0.19, 0.26, 0.49, 0.57, 0.0, 0.32, 0.01, 0.6, 0.09, 0.58, 0.01, 0.46, 0.38, 0.08, 0.56, 0.54, 0.25, 0.12, 0.66, 0.16, 0.07, 0.59, 0.52, 0.56, 0.7, 0.48, 0.46, 0.23, 0.22, 0.48, 0.13, 0.34, 0.19, 0.0, 0.16, 0.03, 0.47, 0.83, 0.69, 0.07, 0.03, 0.22, 0.0, 0.01, 0.0, 0.29, 0.01, 0.1, 0.01, 0.18, 0.15, 0.32, 0.73, 0.72, 0.0, 0.75, 0.48, 0.57, 0.23, 0.0, 0.0, 0.0, 0.11, 0.01, 0.02, 0.01, 0.17, 0.48, 0.2, 0.85, 0.22, 0.03, 0.75, 0.84, 0.22, 0.71, 0.29, 0.33, 0.0, 0.63, 0.13, 0.4, 0.0, 0.19, 0.02, 0.11, 0.0, 0.17, 0.07, 0.19, 0.58, 0.73, 0.86, 0.45, 0.31, 0.12, 0.61, 0.36, 0.55, 0.22, 0.84, 0.09, 0.51, 0.42, 0.8, 0.29, 0.55, 0.07, 0.04, 0.41, 0.56, 0.07, 0.77, 0.75, 0.71, 0.49, 0.17, 0.67, 0.27, 0.25, 0.49, 0.22, 0.29, 0.49, 0.06, 0.0, 0.37, 0.08, 0.63, 0.32, 0.02, 0.66, 0.74, 0.41, 0.73, 0.15, 0.0, 0.28, 0.54, 0.97, 0.39, 0.02, 0.0, 0.26, 0.0, 0.28, 0.0, 0.3, 0.04, 0.41, 0.37, 0.7, 0.63, 0.48]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 90.2801
| 0.422735
| 1,582
|
O43255
|
Q13118
| null |
degron_data
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
KLF10
|
MLNFGASLQQTAEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYVENRPVTPVSDLSEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFKSLSDTAKPHIAAPFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ
|
Homo sapiens
|
Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '71.5', 'Basal respiratory cells': '107.9', 'Club cells': '35.8', 'Ionocytes': '45.7', 'Mucus glandular cells': '115.9', 'Serous glandular cells': '145.7', 'Gastric mucus-secreting cells': '48.3', 'Proximal enterocytes': '37.1', 'Paneth cells': '47.7', 'Distal enterocytes': '62.7', 'Intestinal goblet cells': '40.1', 'Exocrine glandular cells': '-0.493', 'Basal prostatic cells': '87.9', 'Prostatic glandular cells': '7.1', 'Breast glandular cells': '0.132', 'Breast myoepithelial cells': '0.357', 'Glandular and luminal cells': '181.7', 'Secretory cells': '153.6', 'Basal keratinocytes': '91.1', 'Suprabasal keratinocytes': '106.1', 'Basal squamous epithelial cells': '269.9', 'Squamous epithelial cells': '210.2', 'Alveolar cells type 1': '0.307', 'Alveolar cells type 2': '0.117', 'Salivary duct cells': '146.6', 'Ductal cells': '0.375', 'Hepatocytes': '0.002', 'Cholangiocytes': '42.0', 'Proximal tubular cells': '0.168', 'Distal tubular cells': '15.4', 'Collecting duct cells': '46.7', 'Mesothelial cells': '-0.112', 'Sertoli cells': '0.336', 'Granulosa cells': '62.0', 'Enteroendocrine cells': '51.1', 'Pancreatic endocrine cells': '23.8', 'Leydig cells': '0.397', 'Excitatory neurons': '6.5', 'Inhibitory neurons': '0.5', 'Cone photoreceptor cells': '3.4', 'Rod photoreceptor cells': '3.1', 'Bipolar cells': '3.7', 'Horizontal cells': '3.8', 'Astrocytes': '0.9', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '0.4', 'Microglial cells': '7.2', 'Muller glia cells': '9.6', 'Schwann cells': '0.096', 'Spermatogonia': '0.581', 'Spermatocytes': '0.483', 'Early spermatids': '-0.024', 'Late spermatids': '-0.363', 'Oocytes': '9.6', 'Cytotrophoblasts': '50.2', 'Syncytiotrophoblasts': '69.7', 'Extravillous trophoblasts': '95.5', 'Endothelial cells': '140.5', 'Lymphatic endothelial cells': '102.9', 'Cardiomyocytes': '0.351', 'Skeletal myocytes': '-0.015', 'Smooth muscle cells': '120.8', 'Adipocytes': '185.9', 'Melanocytes': '0.160', 'Fibroblasts': '114.1', 'Peritubular cells': '0.199', 'Endometrial stromal cells': '114.5', 'Ovarian stromal cells': '47.8', 'Undifferentiated cells': '40.7', 'T-cells': '41.2', 'B-cells': '54.1', 'Plasma cells': '54.1', 'Nk-cells': '20.1', 'Granulocytes': '99.5', 'Monocytes': '91.5', 'Macrophages': '130.2', 'Hofbauer cells': '104.1', 'Kupffer cells': '60.8', 'Dendritic cells': '113.7', 'Langerhans cells': '0.272', 'Erythroid cells': '-0.029', 'Adipocytes (Subcutaneous)': '-0.203', 'Adipocytes (Visceral)': '0.336', 'Breast glandular cells (progenitors)': '0.177', 'Adipocytes (Breast)': '-0.096', 'Colon enterocytes': '0.002', 'Colon enteroendocrine cells': '0.148', 'Enteric glia cells': '-0.410', 'Mitotic cells (Colon)': '0.016', 'Mitotic cells (Heart)': '0.395', 'Podocytes': '-0.004', 'Ascending Loop of Henle cells': '0.212', 'Intercalated cells': '0.101', 'Cholangiocyte': '0.039', 'NK-cells (Liver)': '-0.041', 'Respiratory ciliated cells': '-0.002', 'Mitotic cells (Lung)': '-0.134', 'NK-cells (Lung)': '0.256', 'B-cells (Lung)': '0.033', 'Alpha cells': '0.203', 'Beta cells': '0.121', 'Prostate glandular cells': '-0.270', 'Prostate basal glandular cells': '0.015', 'Urothelial cells': '0.193', 'Keratinocyte (other)': '0.392', 'Keratinocyte (granular)': '0.249', 'Hair cortex cells': '-0.195', 'Inner root sheath cells': '-0.129', 'Outer root sheath cells': '-0.155', 'Sebaceous gland cells': '-0.082', 'Eccrine sweat gland cells': '-0.211', 'Adipocytes (Skin)': '-0.278', 'Mitotic cells (Skin)': '0.051', 'Parietal cells': '-0.485', 'Chief cells': '-0.399', 'Gastric mucous cells': '-0.466', 'Gastric enteroendocrine cells': '-0.386', 'Mitotic cells (Stomach)': '-0.225', 'Parafollicular cells': '0.016', 'Thyroid glandular cells': '0.111', 'Mitotic cells (Thyroid)': '-0.060', 'Adrenal cortex cells': '0.604', 'Adrenal medulla cells': '0.032', 'Mitotic cells (Adrenal gland)': '0.312', 'Minor salivary glandular cells': '0.627', 'Minor salivary gland ductal cells': '-0.007', 'Minor salivary gland basal cells': '0.230', 'Mitotic cells (Minor salivary gland)': '0.351', 'Adipocytes (Minor salivary gland)': '0.218', 'Somatotropes': '-0.228', 'Lactotropes': '-0.175', 'Gonadotropes': '0.076', 'Corticotropes': '0.009', 'Thyrotropes': '0.131', 'Undifferentiated cells (Pituitary gland)': '0.226', 'Mitotic cells (Spleen)': '-0.306', 'Platelets': '-0.032', 'Erythrocytes': '-0.140', 'Hematopoietic stem cells': '-0.098', 'B-cells (Spleen)': '0.014', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '9.3', 'Cerebellar inhibitory': '0.7', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '8.6', 'Deep-layer intratelencephalic': '13.9', 'Deep-layer near-projecting': '1.9', 'Eccentric medium spiny neuron': '10.1', 'Hippocampal ca1-3': '5.6', 'Hippocampal ca4': '4.2', 'Hippocampal dentate gyrus': '3.8', 'Lamp5-lhx6 and chandelier': '0.2', 'Lower rhombic lip': '0.9', 'Mammillary body': '1.2', 'Medium spiny neuron': '4.4', 'Mge interneuron': '0.6', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '7.9', 'Splatter': '2.8', 'Thalamic excitatory': '1.9', 'Upper rhombic lip': '1.9', 'Upper-layer intratelencephalic': '8.6', 'Astrocyte': '4.0', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '5.3', 'Choroid plexus epithelial cell': '3.9', 'Committed oligodendrocyte precursor': '1.2', 'Ependymal cell': '13.4', 'Oligodendrocyte': '0.3', 'Oligodendrocyte precursor cell': '0.6', 'Endothelial cell': '31.9', 'Pericyte': '12.0', 'Vascular associated smooth muscle cell': '22.1', 'Fibroblast': '16.1', 'Leukocyte': '8.5', 'Basophil': '42.1', 'Eosinophil': '14.3', 'Neutrophil': '104.3', 'Classical monocyte': '484.2', 'Non-classical monocyte': '144.4', 'Intermediate monocyte': '419.6', 'T-reg': '15.3', 'GdT-cell': '16.5', 'MAIT T-cell': '19.7', 'Memory CD4 T-cell': '12.5', 'Naive CD4 T-cell': '25.3', 'Memory CD8 T-cell': '17.1', 'Naive CD8 T-cell': '32.5', 'Memory B-cell': '17.2', 'Naive B-cell': '57.9', 'Plasmacytoid DC': '81.0', 'Myeloid DC': '427.8', 'NK-cell': '66.6', 'Total PBMC': '157.2', 'Vd2 gdTCR': '23.3', 'Memory CD4 T-cell Th1\\/Th17': '68.6', 'Memory CD4 T-cell Th17': '45.5', 'Memory CD4 T-cell Th2': '53.8', 'Non-Vd2 gdTCR': '55.4', 'Memory CD4 T-cell Th1': '65.2', 'Memory CD4 T-cell TFH': '20.8', 'Terminal effector memory CD4 T-cell': '50.1', 'Central memory CD8 T-cell': '14.3', 'Effector memory CD8 T-cell': '38.3', 'Terminal effector memory CD8 T-cell': '46.8', 'Non-switched memory B-cell': '69.6', 'Plasmablast': '142.1', 'Switched memory B-cell': '70.3', 'Exhausted memory B-cell': '62.8', 'Progenitor cell': '114.0', 'Memory T-reg': '26.2', 'Naive CD4 T-cell activated': '473.9', 'Naive CD8 T-cell activated': '438.0', 'Naive T-reg': '6.5'}
|
2EPA
|
{'Adipose Tissue': 70.49426411960133, 'Adrenal Gland': 31.772391472868215, 'Bladder': 38.26904761904762, 'Blood': 20.387148869752423, 'Blood Vessel': 50.544841947565544, 'Brain': 4.69623785011355, 'Breast': 63.77302832244008, 'Cervix Uteri': 44.12842105263158, 'Colon': 70.74557766367137, 'Esophagus': 52.99649134948096, 'Fallopian Tube': 80.13777777777779, 'Heart': 20.415876887340303, 'Kidney': 23.367943820224717, 'Liver': 19.808508849557523, 'Lung': 82.575830449827, 'Muscle': 101.40176712328768, 'Nerve': 27.934799676898223, 'Ovary': 42.349866666666664, 'Pancreas': 27.420893292682926, 'Pituitary': 27.620236749116607, 'Prostate': 28.53410612244898, 'Salivary Gland': 37.39051851851852, 'Skin': 75.00376838032062, 'Small Intestine': 37.57407486631016, 'Spleen': 39.15838174273859, 'Stomach': 51.92269359331476, 'Testis': 31.33340720221607, 'Thyroid': 47.36281316998469, 'Uterus': 41.65299295774648, 'Vagina': 45.50525641025641}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[44.63, 44.64, 51.33, 48.31, 45.04, 47.25, 46.31, 44.87, 45.8, 48.72, 46.98, 45.04, 47.31, 47.38, 49.18, 44.67, 48.53, 39.8, 42.25, 41.44, 40.32, 41.59, 37.98, 43.1, 40.94, 36.16, 35.54, 36.93, 35.01, 32.74, 37.2, 43.59, 42.41, 45.22, 42.69, 46.52, 53.48, 54.88, 57.37, 63.6, 67.45, 60.41, 57.01, 64.31, 63.57, 49.87, 64.72, 46.01, 47.74, 46.48, 45.22, 47.71, 45.73, 56.94, 53.78, 56.03, 70.53, 71.32, 64.67, 66.94, 68.38, 64.95, 46.32, 46.49, 45.91, 40.13, 37.84, 33.04, 43.52, 32.49, 41.73, 39.6, 36.33, 43.79, 38.92, 40.07, 39.32, 39.04, 38.71, 33.3, 36.63, 32.21, 34.95, 34.16, 33.15, 36.9, 37.57, 37.68, 36.34, 33.56, 36.59, 33.54, 38.88, 36.37, 42.16, 35.13, 34.82, 35.94, 35.32, 32.14, 35.35, 36.06, 39.55, 35.38, 37.8, 38.68, 38.07, 33.42, 39.0, 42.33, 35.53, 36.83, 36.31, 41.36, 41.21, 36.47, 41.94, 34.84, 35.63, 36.61, 35.47, 35.71, 40.28, 36.84, 35.62, 39.43, 39.82, 46.41, 37.77, 41.54, 34.87, 41.91, 39.82, 35.95, 42.01, 33.08, 38.77, 35.04, 45.83, 35.5, 41.11, 38.56, 38.96, 36.6, 37.12, 38.23, 37.9, 39.31, 37.35, 38.27, 36.81, 36.99, 39.51, 36.14, 37.79, 41.51, 36.23, 36.72, 45.14, 50.14, 44.42, 46.6, 52.35, 51.5, 61.75, 60.35, 70.01, 56.89, 61.92, 45.99, 52.41, 44.67, 39.51, 39.66, 36.56, 37.17, 39.67, 36.93, 36.45, 32.61, 37.49, 31.99, 29.04, 32.66, 35.22, 35.51, 30.92, 34.66, 31.7, 36.19, 33.7, 35.68, 40.59, 37.58, 37.38, 38.14, 38.3, 42.85, 36.07, 35.82, 32.38, 26.77, 34.75, 32.41, 33.02, 27.88, 39.03, 30.94, 31.52, 32.28, 36.84, 28.2, 35.46, 35.69, 37.4, 33.55, 40.22, 38.23, 37.01, 44.55, 40.71, 40.18, 37.66, 32.88, 36.93, 32.51, 38.86, 36.58, 35.64, 30.65, 36.3, 35.48, 28.3, 36.28, 31.27, 32.84, 34.83, 29.72, 33.69, 31.74, 23.54, 29.12, 31.29, 29.99, 31.2, 30.38, 32.51, 32.54, 29.18, 32.8, 29.29, 27.66, 28.21, 24.79, 28.41, 24.51, 29.68, 28.44, 28.61, 32.46, 31.13, 29.98, 35.8, 34.58, 39.25, 30.48, 35.95, 39.32, 43.34, 36.28, 34.32, 35.85, 30.83, 32.04, 30.02, 30.45, 36.41, 34.21, 35.31, 32.85, 41.58, 36.61, 37.78, 37.19, 35.29, 38.38, 35.03, 34.0, 31.99, 35.43, 34.91, 30.11, 42.14, 33.42, 37.2, 38.96, 38.95, 36.59, 39.52, 37.05, 36.7, 36.31, 36.7, 38.79, 39.72, 34.83, 36.33, 33.02, 32.96, 37.95, 42.13, 46.2, 44.2, 35.78, 43.54, 38.46, 44.94, 34.12, 37.38, 38.94, 44.54, 42.07, 35.6, 35.9, 37.24, 42.27, 39.3, 34.02, 36.51, 40.92, 34.63, 34.36, 37.04, 40.92, 39.54, 44.25, 43.76, 41.01, 43.45, 32.81, 39.6, 40.82, 44.21, 45.43, 42.82, 47.49, 46.86, 45.01, 41.55, 41.44, 39.92, 48.08, 40.48, 47.24, 48.93, 49.06, 45.0, 51.8, 46.94, 43.41, 52.18, 46.78, 58.92, 60.06, 59.11, 66.95, 64.72, 82.91, 83.53, 85.61, 89.04, 86.21, 84.06, 84.6, 83.68, 84.66, 83.09, 87.4, 88.43, 87.26, 86.54, 85.24, 86.83, 85.91, 85.92, 88.85, 85.96, 85.02, 86.92, 85.65, 85.18, 83.85, 84.78, 81.81, 80.79, 82.39, 84.81, 84.26, 85.11, 86.72, 89.71, 85.73, 84.04, 81.46, 81.74, 85.3, 84.38, 85.71, 87.43, 85.88, 84.71, 83.75, 87.24, 84.76, 85.44, 89.28, 85.87, 85.17, 88.12, 86.09, 84.28, 84.79, 84.27, 82.2, 79.88, 79.58, 83.39, 83.68, 83.94, 84.98, 86.42, 83.13, 79.74, 86.11, 83.87, 84.37, 87.13, 84.48, 85.51, 84.27, 87.31, 85.25, 87.43, 89.96, 86.29, 86.98, 87.63, 86.17, 85.08, 81.89, 79.47, 68.69, 64.54, 58.35, 53.91, 48.3, 50.34, 47.9, 49.9, 50.95, 51.25, 56.13, 54.2, 56.57, 60.67, 61.9, 56.73, 56.57, 56.49, 56.36, 50.75, 54.07, 48.13, 44.72, 46.37, 40.48, 48.83, 44.23, 37.52, 37.62]
|
[0.99, 0.97, 0.91, 0.86, 0.65, 0.67, 0.61, 0.7, 0.66, 0.69, 0.53, 0.55, 0.67, 0.67, 0.74, 0.79, 0.79, 0.8, 0.77, 0.8, 0.97, 0.92, 0.82, 0.9, 0.87, 0.79, 0.88, 0.93, 0.8, 0.93, 0.61, 0.87, 0.75, 0.5, 0.66, 0.73, 0.57, 0.66, 0.69, 0.65, 0.43, 0.43, 0.57, 0.43, 0.65, 0.62, 0.6, 0.73, 0.45, 0.54, 0.54, 0.59, 0.73, 0.57, 0.56, 0.45, 0.6, 0.5, 0.68, 0.59, 0.66, 0.76, 0.75, 0.85, 0.87, 0.86, 0.86, 0.95, 0.91, 0.97, 0.98, 1.0, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.9, 0.89, 0.81, 0.95, 0.89, 0.86, 0.98, 0.7, 0.9, 0.89, 0.82, 0.81, 0.89, 0.95, 0.92, 0.94, 0.82, 0.92, 0.82, 0.97, 0.83, 0.86, 0.82, 0.76, 0.92, 0.88, 0.9, 0.98, 0.94, 0.99, 0.99, 1.0, 0.98, 0.99, 0.92, 0.91, 0.86, 0.81, 0.94, 0.87, 1.0, 1.0, 1.0, 1.0, 0.94, 0.99, 0.96, 1.0, 0.98, 1.0, 0.93, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 0.99, 1.0, 1.0, 1.0, 0.91, 1.0, 0.96, 0.97, 0.97, 0.91, 0.9, 0.81, 0.86, 0.72, 0.8, 0.73, 0.81, 0.86, 0.87, 0.77, 0.85, 0.92, 0.67, 0.93, 0.81, 0.58, 0.87, 0.67, 0.97, 0.88, 0.44, 0.74, 0.9, 0.83, 0.97, 0.99, 0.99, 1.0, 0.99, 1.0, 0.98, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 0.96, 1.0, 0.97, 1.0, 0.94, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.91, 0.99, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.86, 1.0, 0.87, 1.0, 0.92, 1.0, 1.0, 0.94, 1.0, 0.94, 1.0, 1.0, 0.99, 0.99, 0.99, 0.99, 0.99, 0.89, 0.92, 0.86, 0.85, 0.96, 0.95, 0.93, 0.97, 1.0, 0.98, 0.97, 0.93, 0.99, 0.95, 1.0, 0.95, 0.99, 0.89, 0.99, 0.98, 0.99, 0.97, 0.99, 1.0, 0.96, 0.98, 0.85, 0.96, 0.88, 0.91, 0.99, 0.96, 0.95, 0.96, 0.92, 0.93, 0.93, 1.0, 0.96, 0.93, 0.94, 0.9, 0.88, 0.81, 0.88, 0.82, 0.84, 0.76, 0.78, 0.94, 0.9, 0.89, 0.95, 0.92, 0.82, 0.92, 0.72, 0.83, 0.69, 0.78, 0.78, 0.81, 0.77, 0.89, 0.84, 0.86, 0.98, 0.81, 0.97, 0.98, 0.88, 0.84, 0.93, 0.9, 0.88, 0.89, 0.76, 0.79, 0.74, 0.88, 0.95, 0.88, 0.96, 0.67, 0.77, 0.98, 0.87, 0.51, 0.76, 0.68, 0.8, 0.87, 0.73, 0.84, 0.84, 0.82, 0.85, 0.83, 0.84, 0.85, 0.89, 0.94, 0.89, 0.86, 0.88, 0.86, 0.82, 0.93, 0.9, 1.0, 0.88, 1.0, 0.93, 0.9, 0.98, 0.94, 0.91, 0.94, 0.93, 0.99, 0.94, 0.96, 0.91, 0.88, 0.9, 0.89, 0.76, 0.91, 0.86, 0.83, 0.77, 0.85, 0.67, 0.51, 0.68, 0.77, 0.87, 0.4, 0.83, 0.44, 0.29, 0.58, 0.08, 0.87, 0.48, 0.94, 0.99, 0.19, 0.63, 0.49, 0.62, 0.24, 0.69, 0.6, 0.52, 0.63, 0.54, 0.17, 0.64, 0.18, 0.06, 0.35, 0.27, 0.65, 0.38, 0.63, 0.53, 0.58, 0.52, 0.55, 0.33, 0.52, 0.12, 0.85, 0.56, 0.98, 0.93, 0.11, 0.89, 0.51, 0.56, 0.15, 0.2, 0.42, 0.53, 0.51, 0.25, 0.15, 0.46, 0.35, 0.07, 0.58, 0.3, 0.55, 0.27, 0.53, 0.49, 0.43, 0.49, 0.5, 0.12, 0.45, 0.09, 0.6, 0.38, 0.28, 0.92, 0.55, 0.59, 0.17, 0.2, 0.28, 0.47, 0.38, 0.44, 0.03, 0.41, 0.5, 0.11, 0.03, 0.57, 0.67, 0.21, 0.29, 0.75, 0.79, 0.67, 0.96, 0.54, 0.92, 0.54, 0.58, 0.81, 0.57, 0.41, 0.29, 0.46, 0.63, 0.19, 0.71, 0.7, 0.42, 0.84, 0.69, 0.72, 0.91, 0.92, 0.9, 0.8, 0.88, 0.94, 0.94]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 48.661458
| 0.784542
| 1,654
|
O43255
|
Q13625
|
nan, 23644657
|
degron_data, UbiNet, UbiBrowser, 31181401
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
TP53BP2
|
MMPMFLTVYLSNNEQHFTEVPVTPETICRDVVDLCKEPGESDCHLAEVWCGSERPVADNERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRRKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRPELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENIYSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA
|
Homo sapiens
|
Cytoplasm, perinuclear region, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '24.6', 'Basal respiratory cells': '7.1', 'Club cells': '16.8', 'Ionocytes': '10.3', 'Mucus glandular cells': '41.7', 'Serous glandular cells': '22.8', 'Gastric mucus-secreting cells': '16.5', 'Proximal enterocytes': '5.2', 'Paneth cells': '7.3', 'Distal enterocytes': '14.1', 'Intestinal goblet cells': '10.6', 'Exocrine glandular cells': '-0.669', 'Basal prostatic cells': '18.6', 'Prostatic glandular cells': '14.4', 'Breast glandular cells': '0.508', 'Breast myoepithelial cells': '0.590', 'Glandular and luminal cells': '140.4', 'Secretory cells': '71.8', 'Basal keratinocytes': '17.5', 'Suprabasal keratinocytes': '13.8', 'Basal squamous epithelial cells': '23.9', 'Squamous epithelial cells': '18.4', 'Alveolar cells type 1': '0.436', 'Alveolar cells type 2': '0.121', 'Salivary duct cells': '39.9', 'Ductal cells': '0.751', 'Hepatocytes': '0.239', 'Cholangiocytes': '19.1', 'Proximal tubular cells': '0.143', 'Distal tubular cells': '3.1', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.308', 'Sertoli cells': '0.701', 'Granulosa cells': '10.0', 'Enteroendocrine cells': '7.2', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '0.614', 'Excitatory neurons': '1.6', 'Inhibitory neurons': '5.1', 'Cone photoreceptor cells': '59.5', 'Rod photoreceptor cells': '40.7', 'Bipolar cells': '11.3', 'Horizontal cells': '0.6', 'Astrocytes': '72.5', 'Oligodendrocyte precursor cells': '25.5', 'Oligodendrocytes': '27.0', 'Microglial cells': '22.4', 'Muller glia cells': '9.7', 'Schwann cells': '0.071', 'Spermatogonia': '0.673', 'Spermatocytes': '0.426', 'Early spermatids': '-0.454', 'Late spermatids': '-0.685', 'Oocytes': '4.4', 'Cytotrophoblasts': '10.2', 'Syncytiotrophoblasts': '5.1', 'Extravillous trophoblasts': '5.7', 'Endothelial cells': '21.6', 'Lymphatic endothelial cells': '29.0', 'Cardiomyocytes': '0.584', 'Skeletal myocytes': '-0.163', 'Smooth muscle cells': '24.9', 'Adipocytes': '17.5', 'Melanocytes': '0.185', 'Fibroblasts': '19.7', 'Peritubular cells': '0.429', 'Endometrial stromal cells': '40.9', 'Ovarian stromal cells': '9.4', 'Undifferentiated cells': '9.9', 'T-cells': '43.7', 'B-cells': '24.4', 'Plasma cells': '22.0', 'Nk-cells': '27.7', 'Granulocytes': '109.3', 'Monocytes': '193.4', 'Macrophages': '45.8', 'Hofbauer cells': '10.5', 'Kupffer cells': '15.8', 'Dendritic cells': '25.3', 'Langerhans cells': '0.186', 'Erythroid cells': '0.052', 'Adipocytes (Subcutaneous)': '-0.468', 'Adipocytes (Visceral)': '-0.295', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.558', 'Colon enterocytes': '-0.085', 'Colon enteroendocrine cells': '0.258', 'Enteric glia cells': '-0.019', 'Mitotic cells (Colon)': '-0.015', 'Mitotic cells (Heart)': '0.535', 'Podocytes': '-0.074', 'Ascending Loop of Henle cells': '0.307', 'Intercalated cells': '-0.108', 'Cholangiocyte': '0.386', 'NK-cells (Liver)': '-0.251', 'Respiratory ciliated cells': '-0.045', 'Mitotic cells (Lung)': '-0.233', 'NK-cells (Lung)': '0.199', 'B-cells (Lung)': '0.006', 'Alpha cells': '0.347', 'Beta cells': '0.219', 'Prostate glandular cells': '-0.342', 'Prostate basal glandular cells': '0.028', 'Urothelial cells': '0.151', 'Keratinocyte (other)': '0.271', 'Keratinocyte (granular)': '0.061', 'Hair cortex cells': '-0.072', 'Inner root sheath cells': '0.043', 'Outer root sheath cells': '0.094', 'Sebaceous gland cells': '-0.100', 'Eccrine sweat gland cells': '0.029', 'Adipocytes (Skin)': '-0.131', 'Mitotic cells (Skin)': '0.265', 'Parietal cells': '-0.590', 'Chief cells': '-0.498', 'Gastric mucous cells': '-0.341', 'Gastric enteroendocrine cells': '-0.389', 'Mitotic cells (Stomach)': '0.020', 'Parafollicular cells': '0.123', 'Thyroid glandular cells': '0.329', 'Mitotic cells (Thyroid)': '-0.021', 'Adrenal cortex cells': '0.388', 'Adrenal medulla cells': '0.007', 'Mitotic cells (Adrenal gland)': '0.251', 'Minor salivary glandular cells': '0.644', 'Minor salivary gland ductal cells': '0.100', 'Minor salivary gland basal cells': '0.335', 'Mitotic cells (Minor salivary gland)': '0.325', 'Adipocytes (Minor salivary gland)': '0.157', 'Somatotropes': '-0.096', 'Lactotropes': '-0.372', 'Gonadotropes': '-0.198', 'Corticotropes': '-0.319', 'Thyrotropes': '-0.239', 'Undifferentiated cells (Pituitary gland)': '0.362', 'Mitotic cells (Spleen)': '-0.166', 'Platelets': '-0.058', 'Erythrocytes': '-0.114', 'Hematopoietic stem cells': '-0.165', 'B-cells (Spleen)': '0.384', 'NK-cells (Spleen)': '0.247', 'Amygdala excitatory': '7.5', 'Cerebellar inhibitory': '1.6', 'Cge interneuron': '7.6', 'Deep-layer corticothalamic and 6b': '7.2', 'Deep-layer intratelencephalic': '5.1', 'Deep-layer near-projecting': '3.5', 'Eccentric medium spiny neuron': '10.3', 'Hippocampal ca1-3': '7.6', 'Hippocampal ca4': '5.7', 'Hippocampal dentate gyrus': '2.4', 'Lamp5-lhx6 and chandelier': '7.6', 'Lower rhombic lip': '2.3', 'Mammillary body': '13.0', 'Medium spiny neuron': '6.6', 'Mge interneuron': '8.7', 'Midbrain-derived inhibitory': '33.8', 'Miscellaneous': '5.5', 'Splatter': '7.0', 'Thalamic excitatory': '2.1', 'Upper rhombic lip': '9.9', 'Upper-layer intratelencephalic': '2.7', 'Astrocyte': '121.7', 'Bergmann glia': '85.1', 'Central nervous system macrophage': '46.6', 'Choroid plexus epithelial cell': '81.2', 'Committed oligodendrocyte precursor': '44.3', 'Ependymal cell': '52.5', 'Oligodendrocyte': '51.7', 'Oligodendrocyte precursor cell': '49.4', 'Endothelial cell': '36.9', 'Pericyte': '31.9', 'Vascular associated smooth muscle cell': '58.1', 'Fibroblast': '36.3', 'Leukocyte': '50.6', 'Basophil': '11.5', 'Eosinophil': '0.8', 'Neutrophil': '8.7', 'Classical monocyte': '70.7', 'Non-classical monocyte': '54.8', 'Intermediate monocyte': '10.9', 'T-reg': '10.3', 'GdT-cell': '0.9', 'MAIT T-cell': '10.2', 'Memory CD4 T-cell': '1.1', 'Naive CD4 T-cell': '46.3', 'Memory CD8 T-cell': '1.7', 'Naive CD8 T-cell': '32.4', 'Memory B-cell': '0.9', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '6.4', 'Myeloid DC': '9.6', 'NK-cell': '52.2', 'Total PBMC': '9.1', 'Vd2 gdTCR': '11.8', 'Memory CD4 T-cell TFH': '60.9', 'Memory CD4 T-cell Th2': '70.1', 'Memory CD4 T-cell Th17': '63.0', 'Memory CD4 T-cell Th1\\/Th17': '65.8', 'Non-Vd2 gdTCR': '8.5', 'Memory CD4 T-cell Th1': '66.8', 'Terminal effector memory CD4 T-cell': '9.9', 'Central memory CD8 T-cell': '10.1', 'Effector memory CD8 T-cell': '11.2', 'Terminal effector memory CD8 T-cell': '10.8', 'Switched memory B-cell': '5.6', 'Plasmablast': '4.1', 'Non-switched memory B-cell': '8.7', 'Exhausted memory B-cell': '13.7', 'Progenitor cell': '6.8', 'Memory T-reg': '41.1', 'Naive CD4 T-cell activated': '213.7', 'Naive CD8 T-cell activated': '133.8', 'Naive T-reg': '38.9'}
|
1YCS, 2UWQ, 4A63, 4IRV, 6GHM, 6HKP
|
{'Adipose Tissue': 18.908493355481728, 'Adrenal Gland': 10.809027131782946, 'Bladder': 19.514285714285716, 'Blood': 6.40221162540366, 'Blood Vessel': 38.00467565543071, 'Brain': 26.312317562452687, 'Breast': 17.13165359477124, 'Cervix Uteri': 22.488947368421055, 'Colon': 14.998155327342747, 'Esophagus': 20.183804152249134, 'Fallopian Tube': 21.482222222222223, 'Heart': 7.857776655052264, 'Kidney': 10.188280898876403, 'Liver': 8.745030973451327, 'Lung': 35.42721453287197, 'Muscle': 9.584617683686178, 'Nerve': 25.805218093699516, 'Ovary': 23.762666666666664, 'Pancreas': 6.356792682926828, 'Pituitary': 13.268978798586572, 'Prostate': 15.802502040816323, 'Salivary Gland': 18.44667901234568, 'Skin': 20.2703178551686, 'Small Intestine': 15.897315508021393, 'Spleen': 14.398647302904564, 'Stomach': 15.973295264623957, 'Testis': 20.532462603878116, 'Thyroid': 36.29759571209801, 'Uterus': 25.162887323943664, 'Vagina': 21.837307692307693}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[47.73, 55.99, 64.89, 76.7, 84.28, 87.87, 88.73, 90.5, 89.03, 85.48, 78.49, 79.01, 72.62, 76.47, 75.07, 80.98, 87.71, 87.66, 88.73, 86.37, 86.74, 83.85, 84.02, 83.34, 84.13, 87.37, 90.55, 89.39, 88.39, 89.28, 88.69, 89.37, 86.91, 85.6, 85.62, 84.91, 78.45, 75.76, 71.46, 76.7, 70.64, 81.09, 84.38, 87.91, 89.86, 89.23, 89.37, 87.45, 83.98, 78.17, 75.9, 80.32, 84.26, 86.68, 87.62, 86.42, 87.07, 86.49, 87.13, 86.73, 87.53, 86.26, 84.19, 85.08, 83.83, 82.68, 82.26, 82.56, 80.04, 77.31, 74.7, 73.55, 74.82, 73.95, 81.22, 85.09, 86.46, 90.11, 89.34, 88.46, 86.1, 82.81, 75.35, 70.95, 65.16, 59.9, 57.72, 45.78, 38.04, 40.79, 37.07, 38.33, 32.4, 40.92, 32.65, 39.67, 37.86, 35.12, 35.73, 38.48, 43.51, 39.65, 36.42, 37.36, 38.9, 46.83, 40.78, 41.16, 41.91, 46.66, 36.55, 33.21, 36.13, 41.56, 42.83, 40.38, 37.64, 39.88, 42.42, 38.91, 39.56, 49.33, 40.46, 54.67, 49.17, 63.23, 75.22, 81.16, 86.7, 85.7, 86.53, 88.67, 90.14, 87.8, 90.42, 92.88, 93.8, 94.5, 93.74, 94.98, 94.36, 92.78, 94.73, 94.53, 94.91, 94.66, 95.2, 94.8, 93.23, 94.84, 93.85, 94.88, 94.05, 94.41, 93.29, 92.12, 93.84, 93.66, 90.42, 91.06, 91.24, 89.21, 89.62, 89.98, 88.26, 88.12, 88.1, 89.16, 89.06, 89.92, 90.35, 90.19, 91.38, 91.52, 92.09, 90.6, 92.37, 92.48, 91.77, 93.22, 92.74, 93.45, 92.98, 93.27, 93.02, 92.57, 91.68, 92.71, 92.91, 91.4, 93.21, 91.6, 90.84, 92.1, 91.38, 91.98, 92.08, 90.99, 88.67, 91.74, 90.12, 90.45, 91.64, 92.18, 88.94, 91.05, 91.47, 93.01, 92.23, 91.56, 92.94, 93.11, 92.81, 92.83, 92.2, 93.47, 90.17, 93.14, 93.55, 91.68, 90.62, 91.88, 92.57, 92.0, 91.3, 93.08, 90.8, 93.12, 93.36, 92.76, 91.24, 93.38, 92.98, 92.32, 92.87, 91.8, 91.2, 90.23, 90.8, 88.32, 86.02, 86.37, 85.57, 80.67, 80.58, 79.97, 73.05, 57.35, 55.1, 55.27, 47.1, 44.3, 45.8, 51.01, 53.38, 53.66, 58.84, 65.99, 69.78, 78.87, 79.37, 79.04, 82.88, 83.16, 86.08, 87.72, 88.73, 89.98, 87.27, 89.44, 88.72, 88.06, 86.05, 89.84, 92.27, 89.77, 89.23, 90.08, 90.07, 83.81, 91.1, 93.44, 91.41, 89.47, 91.46, 92.54, 89.01, 92.15, 92.24, 89.94, 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30.35, 29.54, 28.74, 29.81, 31.3, 31.18, 31.51, 32.25, 28.66, 34.14, 39.05, 32.2, 33.56, 34.79, 36.22, 34.25, 38.65, 33.19, 35.67, 33.11, 35.03, 33.65, 36.28, 41.16, 31.46, 34.16, 38.25, 35.78, 37.87, 38.36, 34.83, 34.42, 36.89, 37.59, 37.84, 30.81, 33.45, 33.8, 34.66, 30.81, 35.49, 35.73, 34.44, 37.4, 36.18, 40.84, 36.68, 37.14, 41.38, 40.13, 33.0, 36.42, 38.22, 32.16, 37.67, 36.9, 34.95, 37.34, 33.95, 34.91, 36.44, 33.55, 35.51, 37.22, 40.96, 40.08, 37.36, 48.94, 40.9, 30.96, 38.71, 34.47, 31.15, 35.01, 30.71, 34.59, 38.01, 31.26, 34.31, 33.81, 39.78, 34.78, 33.65, 41.63, 43.17, 43.26, 39.47, 37.92, 38.88, 36.92, 43.16, 32.57, 34.26, 32.16, 36.93, 36.97, 34.72, 32.14, 29.39, 28.87, 32.54, 30.44, 38.91, 34.94, 38.12, 36.24, 35.53, 36.22, 39.14, 32.05, 39.14, 33.98, 37.95, 38.53, 35.26, 38.0, 32.46, 35.16, 34.56, 37.16, 33.39, 38.61, 29.72, 37.82, 36.05, 29.53, 33.54, 34.79, 35.63, 33.89, 35.31, 32.62, 34.72, 29.98, 39.92, 36.9, 31.14, 35.37, 30.87, 32.09, 35.3, 54.22, 45.94, 32.72, 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|
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0.31, 0.47, 0.86, 0.03, 0.24, 0.0, 0.24, 0.01, 0.01, 0.37, 0.52, 0.13, 0.84, 0.42, 0.82, 0.55, 0.97, 0.44, 0.12, 0.02, 0.45, 0.01, 0.49, 0.45, 0.4, 0.28, 0.5, 0.0, 0.35, 0.07, 0.5, 0.39, 0.22, 0.74, 0.31, 0.98, 0.96, 0.42, 0.57, 0.52, 0.28, 0.01, 0.22, 0.0, 0.47, 0.11, 0.83, 0.98, 0.64, 0.41, 0.0, 0.21, 0.0, 0.08, 0.19, 0.46, 0.21, 0.0, 0.0, 0.04, 0.39, 0.39, 0.19, 0.38, 0.77, 0.68, 0.68, 0.87, 0.53, 0.86, 0.93, 0.97]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 60.785975
| 0.7168
| 390
|
O43255
|
Q14807
| null |
degron_data
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
KIF22
|
MAAGGSTQQRRREMAAASAAAISGAGRCRLSKIGATRRPPPARVRVAVRLRPFVDGTAGASDPPCVRGMDSCSLEIANWRNHQETLKYQFDAFYGERSTQQDIYAGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREEGAEGRPWALSVTMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLSQKPISSFADFERHFLPASRNRTVGATRLNQRSSRSHAVLLVKVDQRERLAPFRQREGKLYLIDLAGSEDNRRTGNKGLRLKESGAINTSLFVLGKVVDALNQGLPRVPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYLDTVSALNFAARSKEVINRPFTNESLQPHALGPVKLSQKELLGPPEAKRARGPEEEEIGSPEPMAAPASASQKLSPLQKLSSMDPAMLERLLSLDRLLASQGSQGAPLLSTPKRERMVLMKTVEEKDLEIERLKTKQKELEAKMLAQKAEEKENHCPTMLRPLSHRTVTGAKPLKKAVVMPLQLIQEQAASPNAEIHILKNKGRKRKLESLDALEPEEKAEDCWELQISPELLAHGRQKILDLLNEGSARDLRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGKQMESFLKANILGLAAGQRCGAS
|
Homo sapiens
|
Nucleus, Cytoplasm, cytoskeleton
|
Tissue enhanced (lymphoid)
|
{'Ciliated cells': '24.3', 'Basal respiratory cells': '52.8', 'Club cells': '30.3', 'Ionocytes': '32.0', 'Mucus glandular cells': '11.6', 'Serous glandular cells': '21.2', 'Gastric mucus-secreting cells': '24.8', 'Proximal enterocytes': '12.4', 'Paneth cells': '48.7', 'Distal enterocytes': '56.0', 'Intestinal goblet cells': '39.4', 'Exocrine glandular cells': '-0.590', 'Basal prostatic cells': '77.5', 'Prostatic glandular cells': '57.7', 'Breast glandular cells': '0.713', 'Breast myoepithelial cells': '0.686', 'Glandular and luminal cells': '33.1', 'Secretory cells': '32.7', 'Basal keratinocytes': '29.2', 'Suprabasal keratinocytes': '24.6', 'Basal squamous epithelial cells': '45.7', 'Squamous epithelial cells': '38.1', 'Alveolar cells type 1': '-0.018', 'Alveolar cells type 2': '0.018', 'Salivary duct cells': '13.7', 'Ductal cells': '0.422', 'Hepatocytes': '0.481', 'Cholangiocytes': '49.6', 'Proximal tubular cells': '0.134', 'Distal tubular cells': '64.5', 'Collecting duct cells': '62.2', 'Mesothelial cells': '0.413', 'Sertoli cells': '0.231', 'Granulosa cells': '22.9', 'Enteroendocrine cells': '40.4', 'Pancreatic endocrine cells': '27.2', 'Leydig cells': '0.092', 'Excitatory neurons': '4.6', 'Inhibitory neurons': '5.9', 'Cone photoreceptor cells': '20.4', 'Rod photoreceptor cells': '20.8', 'Bipolar cells': '24.2', 'Horizontal cells': '15.1', 'Astrocytes': '5.3', 'Oligodendrocyte precursor cells': '3.8', 'Oligodendrocytes': '4.9', 'Microglial cells': '4.5', 'Muller glia cells': '72.3', 'Schwann cells': '0.202', 'Spermatogonia': '0.462', 'Spermatocytes': '0.579', 'Early spermatids': '0.117', 'Late spermatids': '-0.158', 'Oocytes': '96.3', 'Cytotrophoblasts': '82.6', 'Syncytiotrophoblasts': '87.8', 'Extravillous trophoblasts': '88.9', 'Endothelial cells': '23.9', 'Lymphatic endothelial cells': '19.8', 'Cardiomyocytes': '0.597', 'Skeletal myocytes': '0.371', 'Smooth muscle cells': '30.7', 'Adipocytes': '16.5', 'Melanocytes': '0.432', 'Fibroblasts': '45.0', 'Peritubular cells': '0.044', 'Endometrial stromal cells': '18.7', 'Ovarian stromal cells': '50.5', 'Undifferentiated cells': '53.5', 'T-cells': '29.5', 'B-cells': '21.3', 'Plasma cells': '52.2', 'Nk-cells': '25.2', 'Granulocytes': '32.1', 'Monocytes': '25.6', 'Macrophages': '30.8', 'Hofbauer cells': '47.9', 'Kupffer cells': '44.6', 'Dendritic cells': '9.3', 'Langerhans cells': '0.373', 'Erythroid cells': '0.072', 'Adipocytes (Subcutaneous)': '-0.232', 'Adipocytes (Visceral)': '-0.219', 'Breast glandular cells (progenitors)': '0.569', 'Adipocytes (Breast)': '-0.652', 'Colon enterocytes': '0.268', 'Colon enteroendocrine cells': '0.049', 'Enteric glia cells': '-0.059', 'Mitotic cells (Colon)': '0.202', 'Mitotic cells (Heart)': '0.303', 'Podocytes': '-0.143', 'Ascending Loop of Henle cells': '0.543', 'Intercalated cells': '0.047', 'Cholangiocyte': '0.072', 'NK-cells (Liver)': '0.127', 'Respiratory ciliated cells': '0.188', 'Mitotic cells (Lung)': '0.450', 'NK-cells (Lung)': '0.101', 'B-cells (Lung)': '0.110', 'Alpha cells': '0.292', 'Beta cells': '0.217', 'Prostate glandular cells': '0.431', 'Prostate basal glandular cells': '0.423', 'Urothelial cells': '0.241', 'Keratinocyte (other)': '0.669', 'Keratinocyte (granular)': '-0.042', 'Hair cortex cells': '-0.171', 'Inner root sheath cells': '-0.065', 'Outer root sheath cells': '0.006', 'Sebaceous gland cells': '-0.091', 'Eccrine sweat gland cells': '-0.339', 'Adipocytes (Skin)': '-0.494', 'Mitotic cells (Skin)': '0.551', 'Parietal cells': '-0.109', 'Chief cells': '-0.055', 'Gastric mucous cells': '0.288', 'Gastric enteroendocrine cells': '0.067', 'Mitotic cells (Stomach)': '0.620', 'Parafollicular cells': '0.137', 'Thyroid glandular cells': '0.409', 'Mitotic cells (Thyroid)': '-0.016', 'Adrenal cortex cells': '0.294', 'Adrenal medulla cells': '0.086', 'Mitotic cells (Adrenal gland)': '0.396', 'Minor salivary glandular cells': '0.203', 'Minor salivary gland ductal cells': '-0.112', 'Minor salivary gland basal cells': '0.705', 'Mitotic cells (Minor salivary gland)': '0.724', 'Adipocytes (Minor salivary gland)': '0.299', 'Somatotropes': '-0.128', 'Lactotropes': '0.014', 'Gonadotropes': '0.140', 'Corticotropes': '0.088', 'Thyrotropes': '0.191', 'Undifferentiated cells (Pituitary gland)': '0.270', 'Mitotic cells (Spleen)': '0.585', 'Platelets': '-0.052', 'Erythrocytes': '0.215', 'Hematopoietic stem cells': '0.066', 'B-cells (Spleen)': '0.238', 'NK-cells (Spleen)': '0.094', 'Amygdala excitatory': '10.1', 'Cerebellar inhibitory': '11.5', 'Cge interneuron': '15.8', 'Deep-layer corticothalamic and 6b': '10.9', 'Deep-layer intratelencephalic': '10.0', 'Deep-layer near-projecting': '12.1', 'Eccentric medium spiny neuron': '13.1', 'Hippocampal ca1-3': '9.3', 'Hippocampal ca4': '12.2', 'Hippocampal dentate gyrus': '11.6', 'Lamp5-lhx6 and chandelier': '14.4', 'Lower rhombic lip': '16.5', 'Mammillary body': '18.6', 'Medium spiny neuron': '12.5', 'Mge interneuron': '13.9', 'Midbrain-derived inhibitory': '30.5', 'Miscellaneous': '9.7', 'Splatter': '15.9', 'Thalamic excitatory': '11.6', 'Upper rhombic lip': '19.6', 'Upper-layer intratelencephalic': '10.3', 'Astrocyte': '21.2', 'Bergmann glia': '18.4', 'Central nervous system macrophage': '11.3', 'Choroid plexus epithelial cell': '11.5', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '17.5', 'Oligodendrocyte': '12.6', 'Oligodendrocyte precursor cell': '12.4', 'Endothelial cell': '9.6', 'Pericyte': '16.0', 'Vascular associated smooth muscle cell': '19.8', 'Fibroblast': '26.4', 'Leukocyte': '22.5', 'Basophil': '24.3', 'Eosinophil': '32.5', 'Neutrophil': '9.5', 'Classical monocyte': '10.1', 'Non-classical monocyte': '17.0', 'Intermediate monocyte': '29.7', 'T-reg': '49.2', 'GdT-cell': '39.9', 'MAIT T-cell': '39.7', 'Memory CD4 T-cell': '43.3', 'Naive CD4 T-cell': '50.4', 'Memory CD8 T-cell': '46.6', 'Naive CD8 T-cell': '51.5', 'Memory B-cell': '24.2', 'Naive B-cell': '21.5', 'Plasmacytoid DC': '16.4', 'Myeloid DC': '15.7', 'NK-cell': '53.8', 'Total PBMC': '27.4', 'Vd2 gdTCR': '36.6', 'Memory CD4 T-cell Th1\\/Th17': '54.3', 'Memory CD4 T-cell Th17': '70.4', 'Memory CD4 T-cell Th2': '73.9', 'Non-Vd2 gdTCR': '49.1', 'Memory CD4 T-cell Th1': '77.3', 'Memory CD4 T-cell TFH': '93.6', 'Terminal effector memory CD4 T-cell': '66.9', 'Central memory CD8 T-cell': '41.0', 'Effector memory CD8 T-cell': '55.9', 'Terminal effector memory CD8 T-cell': '46.1', 'Non-switched memory B-cell': '28.4', 'Plasmablast': '72.0', 'Switched memory B-cell': '35.5', 'Exhausted memory B-cell': '36.5', 'Progenitor cell': '25.7', 'Memory T-reg': '95.0', 'Naive CD4 T-cell activated': '18.2', 'Naive CD8 T-cell activated': '24.2', 'Naive T-reg': '54.0'}
|
2EDU, 6NJE
|
{'Adipose Tissue': 11.376390365448504, 'Adrenal Gland': 8.589713178294573, 'Bladder': 15.476714285714287, 'Blood': 24.7057345532831, 'Blood Vessel': 14.226916104868916, 'Brain': 9.7878315669947, 'Breast': 17.74922440087146, 'Cervix Uteri': 15.907368421052633, 'Colon': 16.801667522464697, 'Esophagus': 15.742590311418686, 'Fallopian Tube': 15.530555555555557, 'Heart': 7.62959430894309, 'Kidney': 10.838808988764043, 'Liver': 6.996243805309735, 'Lung': 14.977318339100345, 'Muscle': 5.569960149439601, 'Nerve': 18.755242326332795, 'Ovary': 14.971027777777778, 'Pancreas': 4.727390243902439, 'Pituitary': 15.806335689045936, 'Prostate': 28.59808163265306, 'Salivary Gland': 13.21441975308642, 'Skin': 35.30904422332781, 'Small Intestine': 22.425716577540108, 'Spleen': 25.16746887966805, 'Stomach': 11.133189415041782, 'Testis': 51.964847645429366, 'Thyroid': 48.54188055130169, 'Uterus': 15.22199295774648, 'Vagina': 20.119153846153846}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[39.33, 40.08, 41.25, 39.59, 39.42, 44.25, 46.26, 46.7, 45.19, 47.52, 49.05, 47.2, 45.82, 43.6, 45.06, 40.82, 40.61, 42.36, 42.11, 38.66, 37.58, 47.31, 43.68, 33.66, 38.28, 31.74, 40.75, 32.69, 39.05, 40.04, 39.27, 35.69, 39.69, 36.26, 35.54, 53.23, 59.82, 69.23, 77.79, 87.09, 90.66, 92.8, 94.84, 96.42, 97.2, 97.86, 98.07, 98.3, 97.83, 97.25, 94.64, 92.71, 89.61, 85.07, 64.34, 58.47, 54.3, 43.46, 46.6, 54.05, 61.57, 70.14, 78.9, 86.98, 88.83, 92.29, 90.03, 91.39, 91.07, 92.25, 93.41, 94.34, 93.28, 94.57, 92.48, 91.8, 85.0, 83.33, 77.06, 77.61, 77.23, 71.11, 70.25, 80.85, 84.87, 89.53, 92.51, 95.4, 95.79, 97.23, 96.97, 97.36, 97.68, 97.29, 94.76, 92.65, 93.33, 94.78, 95.7, 96.34, 96.24, 96.21, 96.74, 97.9, 96.82, 94.84, 96.03, 97.25, 96.45, 94.86, 94.88, 95.44, 92.92, 93.78, 93.93, 91.42, 90.69, 91.81, 93.55, 94.62, 96.22, 96.83, 98.06, 97.68, 97.71, 97.02, 95.26, 92.02, 89.92, 88.44, 92.6, 93.34, 95.31, 92.99, 94.13, 97.05, 96.41, 93.18, 91.28, 88.72, 85.23, 89.45, 90.03, 93.7, 96.22, 97.73, 96.87, 95.43, 96.79, 97.1, 95.88, 94.65, 95.41, 95.47, 94.63, 93.68, 92.38, 91.47, 90.09, 88.58, 85.74, 81.51, 80.09, 65.71, 71.47, 78.85, 83.17, 85.9, 89.71, 92.57, 93.9, 96.81, 97.2, 97.28, 96.74, 96.11, 94.49, 93.13, 92.92, 88.92, 87.3, 90.62, 91.49, 93.55, 92.52, 94.4, 92.76, 93.39, 91.36, 82.95, 83.53, 75.38, 85.52, 92.99, 94.11, 93.63, 93.4, 92.05, 87.97, 84.3, 83.17, 76.82, 77.23, 82.02, 87.38, 89.15, 93.1, 92.05, 92.1, 94.79, 95.73, 95.44, 96.22, 96.32, 96.2, 92.21, 94.08, 93.28, 94.35, 94.73, 94.86, 92.28, 95.06, 94.64, 93.12, 89.71, 90.87, 90.93, 87.03, 82.96, 80.32, 80.58, 61.48, 57.21, 57.66, 56.48, 49.4, 50.98, 49.29, 54.34, 63.0, 69.82, 74.7, 78.53, 82.66, 89.43, 93.17, 94.08, 95.64, 96.76, 96.01, 96.66, 95.32, 95.6, 94.12, 92.75, 92.05, 88.66, 84.26, 82.94, 80.76, 85.34, 86.17, 89.41, 90.68, 91.58, 92.57, 93.48, 94.62, 96.49, 96.45, 97.51, 96.81, 95.66, 95.05, 92.76, 91.21, 91.73, 86.01, 79.28, 73.52, 68.6, 69.97, 69.09, 69.82, 73.59, 78.37, 81.94, 80.19, 79.13, 82.46, 84.47, 82.39, 83.61, 85.96, 88.41, 87.09, 89.01, 91.95, 93.62, 93.37, 94.15, 96.07, 96.34, 96.06, 96.92, 97.29, 96.77, 96.46, 97.09, 96.07, 95.94, 94.89, 92.58, 93.72, 90.3, 93.11, 94.69, 95.58, 94.93, 94.34, 94.57, 94.8, 94.37, 94.25, 95.17, 94.12, 93.08, 92.47, 92.43, 87.53, 91.25, 92.39, 89.25, 89.89, 91.11, 93.28, 95.78, 96.92, 97.7, 98.08, 98.38, 98.14, 97.98, 96.79, 93.77, 92.9, 90.04, 87.73, 86.03, 89.04, 91.03, 90.7, 92.09, 93.65, 93.38, 93.7, 95.59, 96.53, 95.72, 96.42, 97.12, 96.56, 96.41, 96.69, 96.0, 95.35, 95.78, 95.49, 94.34, 92.89, 90.54, 88.02, 88.6, 85.05, 84.97, 85.47, 82.26, 67.85, 58.62, 53.21, 43.08, 39.07, 37.22, 36.67, 38.1, 38.61, 38.56, 35.13, 42.98, 40.05, 36.38, 42.47, 44.74, 36.36, 45.92, 45.13, 41.08, 43.81, 45.51, 41.28, 43.49, 40.19, 41.84, 42.97, 34.62, 41.31, 34.62, 38.16, 37.64, 35.63, 38.96, 39.95, 34.97, 36.17, 39.22, 32.13, 35.9, 37.52, 32.2, 34.14, 31.69, 31.23, 31.61, 35.14, 29.93, 36.49, 37.77, 28.24, 35.58, 35.64, 39.72, 45.84, 52.16, 50.76, 70.47, 67.66, 69.62, 59.6, 66.41, 68.4, 67.48, 62.4, 69.26, 71.09, 64.97, 60.36, 69.02, 63.71, 59.16, 56.29, 59.24, 46.54, 38.91, 42.88, 38.98, 42.29, 49.91, 45.66, 50.25, 53.36, 51.72, 57.55, 67.21, 61.23, 70.59, 63.08, 67.75, 68.75, 76.43, 70.31, 71.54, 80.67, 79.27, 78.08, 80.01, 83.22, 80.46, 84.66, 89.25, 85.81, 84.03, 86.83, 90.02, 85.03, 87.52, 88.33, 88.35, 84.81, 86.66, 86.93, 84.63, 84.14, 84.52, 85.73, 81.94, 80.05, 79.49, 75.72, 72.2, 67.21, 61.39, 57.86, 52.85, 48.88, 43.9, 37.9, 30.77, 34.54, 34.79, 31.59, 36.8, 35.28, 33.75, 35.6, 31.94, 31.88, 31.97, 29.32, 36.25, 36.35, 30.69, 35.77, 38.52, 37.48, 43.07, 41.69, 57.65, 58.87, 69.09, 66.69, 51.8, 47.94, 44.26, 47.12, 34.89, 34.16, 30.77, 30.53, 30.79, 30.58, 28.11, 30.32, 31.11, 29.41, 33.52, 29.0, 30.91, 28.98, 33.62, 30.46, 29.28, 32.32, 30.17, 29.33, 34.2, 37.08, 29.02, 32.92, 31.04, 35.23, 34.5, 33.61, 32.21, 35.47, 33.65, 34.84, 35.73, 33.76, 36.79, 33.12, 33.98, 35.39, 30.68, 27.31, 31.09, 28.33, 34.71, 41.92, 58.27, 68.33, 76.97, 76.78, 73.79, 78.39, 82.22, 83.03, 84.1, 89.91, 89.26, 88.74, 91.42, 92.84, 91.3, 91.58, 92.59, 92.76, 90.29, 88.42, 91.14, 90.17, 89.92, 89.48, 90.94, 89.26, 87.35, 88.24, 86.19, 86.57, 88.03, 87.68, 89.81, 90.31, 91.46, 92.84, 92.24, 92.69, 92.68, 92.58, 92.03, 93.52, 92.42, 90.36, 90.13, 90.87, 90.36, 91.36, 92.62, 90.96, 91.7, 89.96, 90.77, 90.87, 89.82, 90.28, 88.26, 89.57, 84.58, 83.33, 86.19, 86.9, 83.83, 83.83, 86.02, 88.73, 85.4, 84.99, 89.04, 86.64, 83.13, 84.02, 85.97, 81.54, 73.17, 72.41, 69.92, 65.51, 56.97, 53.25, 40.34, 34.5, 30.08, 29.91, 29.11, 30.58]
|
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|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 73.433925
| 0.492977
| 1,093
|
O43255
|
Q16633
|
nan, 11483517, SIAH2_HUMAN, E3Net, nan
|
degron_data, UbiNet, UbiBrowser, 31181401, degron_data
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
POU2AF1
|
MLWQKPTAPEQAPAPARPYQGVRVKEPVKELLRRKRGHASSGAAPAPTAVVLPHQPLATYTTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPATLQPLAPWTPYTEYVPHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTRSSATPAVGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDMEDPRRAASSLTIDKLLLEEEDSDAYALNHTLSVEGF
|
Homo sapiens
|
Nucleus
|
Group enriched (intestine, lymphoid tissue, stomach)
|
{'Ciliated cells': '31.7', 'Basal respiratory cells': '11.8', 'Club cells': '12.6', 'Ionocytes': '15.5', 'Mucus glandular cells': '3.2', 'Serous glandular cells': '5.0', 'Gastric mucus-secreting cells': '5.3', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.1', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.4', 'Exocrine glandular cells': '-0.131', 'Basal prostatic cells': '1.8', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.539', 'Breast myoepithelial cells': '0.455', 'Glandular and luminal cells': '0.4', 'Secretory cells': '0.0', 'Basal keratinocytes': '1.2', 'Suprabasal keratinocytes': '0.4', 'Basal squamous epithelial cells': '0.4', 'Squamous epithelial cells': '0.9', 'Alveolar cells type 1': '-0.107', 'Alveolar cells type 2': '0.050', 'Salivary duct cells': '7.0', 'Ductal cells': '0.470', 'Hepatocytes': '0.355', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '0.179', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.158', 'Sertoli cells': '-0.360', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '0.6', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.362', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.4', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.3', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '4.2', 'Microglial cells': '0.9', 'Muller glia cells': '0.0', 'Schwann cells': '0.106', 'Spermatogonia': '-0.306', 'Spermatocytes': '0.084', 'Early spermatids': '0.534', 'Late spermatids': '0.317', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '0.8', 'Lymphatic endothelial cells': '0.3', 'Cardiomyocytes': '0.202', 'Skeletal myocytes': '0.119', 'Smooth muscle cells': '0.7', 'Adipocytes': '0.1', 'Melanocytes': '0.074', 'Fibroblasts': '0.7', 'Peritubular cells': '-0.189', 'Endometrial stromal cells': '0.6', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '0.1', 'T-cells': '2.9', 'B-cells': '106.4', 'Plasma cells': '488.5', 'Nk-cells': '0.5', 'Granulocytes': '0.3', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '0.0', 'Kupffer cells': '3.5', 'Dendritic cells': '0.0', 'Langerhans cells': '0.136', 'Erythroid cells': '0.053', 'Adipocytes (Subcutaneous)': '-0.125', 'Adipocytes (Visceral)': '-0.215', 'Breast glandular cells (progenitors)': '0.477', 'Adipocytes (Breast)': '-0.438', 'Colon enterocytes': '0.299', 'Colon enteroendocrine cells': '0.035', 'Enteric glia cells': '0.117', 'Mitotic cells (Colon)': '0.261', 'Mitotic cells (Heart)': '0.089', 'Podocytes': '-0.125', 'Ascending Loop of Henle cells': '0.157', 'Intercalated cells': '0.043', 'Cholangiocyte': '0.352', 'NK-cells (Liver)': '-0.093', 'Respiratory ciliated cells': '0.353', 'Mitotic cells (Lung)': '0.085', 'NK-cells (Lung)': '0.046', 'B-cells (Lung)': '0.458', 'Alpha cells': '0.228', 'Beta cells': '0.040', 'Prostate glandular cells': '-0.102', 'Prostate basal glandular cells': '0.338', 'Urothelial cells': '0.579', 'Keratinocyte (other)': '-0.144', 'Keratinocyte (granular)': '-0.243', 'Hair cortex cells': '0.186', 'Inner root sheath cells': '0.126', 'Outer root sheath cells': '0.320', 'Sebaceous gland cells': '0.160', 'Eccrine sweat gland cells': '0.320', 'Adipocytes (Skin)': '0.155', 'Mitotic cells (Skin)': '0.129', 'Parietal cells': '0.513', 'Chief cells': '0.624', 'Gastric mucous cells': '0.609', 'Gastric enteroendocrine cells': '0.592', 'Mitotic cells (Stomach)': '0.295', 'Parafollicular cells': '-0.070', 'Thyroid glandular cells': '-0.095', 'Mitotic cells (Thyroid)': '0.315', 'Adrenal cortex cells': '0.131', 'Adrenal medulla cells': '0.230', 'Mitotic cells (Adrenal gland)': '0.200', 'Minor salivary glandular cells': '0.349', 'Minor salivary gland ductal cells': '0.302', 'Minor salivary gland basal cells': '-0.293', 'Mitotic cells (Minor salivary gland)': '-0.134', 'Adipocytes (Minor salivary gland)': '0.181', 'Somatotropes': '-0.164', 'Lactotropes': '-0.099', 'Gonadotropes': '0.121', 'Corticotropes': '-0.143', 'Thyrotropes': '-0.002', 'Undifferentiated cells (Pituitary gland)': '0.297', 'Mitotic cells (Spleen)': '0.587', 'Platelets': '-0.034', 'Erythrocytes': '-0.015', 'Hematopoietic stem cells': '0.016', 'B-cells (Spleen)': '0.323', 'NK-cells (Spleen)': '-0.189', 'Amygdala excitatory': '0.2', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.1', 'Deep-layer corticothalamic and 6b': '0.8', 'Deep-layer intratelencephalic': '0.2', 'Deep-layer near-projecting': '0.2', 'Eccentric medium spiny neuron': '0.1', 'Hippocampal ca1-3': '0.3', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.1', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '1.8', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.1', 'Mge interneuron': '0.2', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.2', 'Splatter': '0.5', 'Thalamic excitatory': '0.2', 'Upper rhombic lip': '0.4', 'Upper-layer intratelencephalic': '0.2', 'Astrocyte': '0.9', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.4', 'Choroid plexus epithelial cell': '244.6', 'Committed oligodendrocyte precursor': '10.6', 'Ependymal cell': '112.7', 'Oligodendrocyte': '31.7', 'Oligodendrocyte precursor cell': '0.5', 'Endothelial cell': '0.8', 'Pericyte': '0.2', 'Vascular associated smooth muscle cell': '0.4', 'Fibroblast': '13.3', 'Leukocyte': '11.3', 'Basophil': '3.7', 'Eosinophil': '0.6', 'Neutrophil': '4.6', 'Classical monocyte': '0.1', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '1.7', 'T-reg': '3.6', 'GdT-cell': '0.3', 'MAIT T-cell': '1.4', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '1.2', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.7', 'Memory B-cell': '33.6', 'Naive B-cell': '94.1', 'Plasmacytoid DC': '3.1', 'Myeloid DC': '1.8', 'NK-cell': '0.2', 'Total PBMC': '16.1', 'Vd2 gdTCR': '1.8', 'Memory CD4 T-cell Th1\\/Th17': '0.3', 'Memory CD4 T-cell Th17': '1.7', 'Memory CD4 T-cell Th2': '1.7', 'Non-Vd2 gdTCR': '1.6', 'Memory CD4 T-cell Th1': '1.1', 'Memory CD4 T-cell TFH': '3.2', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '2.1', 'Effector memory CD8 T-cell': '1.5', 'Terminal effector memory CD8 T-cell': '1.9', 'Non-switched memory B-cell': '207.1', 'Plasmablast': '385.5', 'Switched memory B-cell': '249.0', 'Exhausted memory B-cell': '193.5', 'Progenitor cell': '4.7', 'Memory T-reg': '5.8', 'Naive CD4 T-cell activated': '24.3', 'Naive CD8 T-cell activated': '12.8', 'Naive T-reg': '1.6'}
|
1CQT
|
{'Adipose Tissue': 0.5132585930232558, 'Adrenal Gland': 0.1761840968992248, 'Bladder': 2.4937019047619047, 'Blood': 54.38898525080731, 'Blood Vessel': 0.4543261235955056, 'Brain': 0.378825933005299, 'Breast': 1.4609436296296296, 'Cervix Uteri': 1.490327894736842, 'Colon': 4.6705067394094995, 'Esophagus': 0.9106861626297578, 'Fallopian Tube': 2.1768888888888887, 'Heart': 0.1084263344947735, 'Kidney': 1.1098060674157304, 'Liver': 0.4564277433628319, 'Lung': 3.802662093425605, 'Muscle': 0.0580601232876712, 'Nerve': 0.2375899095315024, 'Ovary': 0.5914286666666667, 'Pancreas': 0.1221831554878048, 'Pituitary': 0.2365998586572437, 'Prostate': 2.254885224489796, 'Salivary Gland': 10.933435802469136, 'Skin': 0.1359182863460475, 'Small Intestine': 36.4891922459893, 'Spleen': 66.9244398340249, 'Stomach': 8.3548256545961, 'Testis': 1.6578069252077563, 'Thyroid': 3.01497730474732, 'Uterus': 0.6242043661971831, 'Vagina': 2.1067390384615385}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[59.75, 56.58, 62.51, 61.44, 68.38, 63.33, 60.79, 59.0, 59.09, 54.21, 61.3, 59.98, 69.85, 75.46, 79.08, 84.63, 89.24, 91.64, 94.7, 95.76, 95.73, 96.17, 95.86, 97.19, 96.48, 94.35, 96.5, 97.14, 96.41, 95.82, 96.37, 96.1, 95.47, 93.82, 92.97, 93.21, 67.0, 57.94, 50.93, 53.02, 43.09, 39.5, 39.86, 38.51, 43.51, 42.79, 48.68, 45.94, 49.08, 51.27, 57.86, 61.15, 58.59, 53.48, 57.21, 51.29, 53.08, 48.7, 40.81, 47.68, 42.93, 53.86, 48.76, 47.22, 48.69, 50.14, 37.41, 48.75, 44.15, 57.25, 43.72, 38.53, 39.52, 40.14, 38.7, 33.73, 41.76, 36.83, 48.17, 40.89, 35.91, 40.6, 41.5, 33.94, 39.6, 41.1, 40.25, 49.46, 48.8, 47.61, 61.66, 54.94, 53.31, 55.66, 51.14, 53.26, 64.9, 58.1, 52.42, 58.82, 61.77, 52.58, 59.04, 55.16, 41.57, 63.98, 55.51, 53.1, 57.77, 58.56, 53.33, 48.87, 43.88, 45.34, 44.25, 37.66, 54.94, 54.8, 56.63, 61.51, 70.1, 75.07, 75.23, 82.39, 81.1, 81.92, 82.41, 79.04, 84.48, 85.48, 83.2, 85.11, 83.24, 84.82, 80.77, 74.64, 67.16, 67.21, 62.56, 61.39, 59.87, 53.22, 53.94, 46.88, 50.16, 56.87, 52.13, 49.49, 42.86, 40.11, 52.49, 40.37, 38.76, 45.63, 41.22, 40.89, 47.29, 35.52, 39.81, 41.95, 41.78, 42.97, 48.11, 41.22, 52.41, 45.78, 44.5, 44.56, 48.53, 47.89, 44.13, 48.2, 56.34, 55.59, 57.29, 55.12, 59.69, 73.2, 58.23, 64.11, 63.17, 63.37, 56.8, 51.32, 48.04, 52.5, 53.01, 45.28, 44.42, 47.42, 51.08, 44.92, 44.91, 41.83, 51.11, 51.54, 50.96, 49.22, 49.15, 55.73, 54.58, 53.39, 57.63, 60.75, 60.1, 59.6, 57.43, 60.57, 61.79, 58.85, 57.97, 58.41, 64.05, 56.81, 59.99, 54.21, 54.65, 52.22, 52.18, 55.0, 53.84, 47.75, 55.99, 50.51, 53.44, 53.36, 55.38, 56.63, 62.59, 68.19, 76.33, 72.38, 74.8, 73.02, 74.64, 74.38, 70.72, 63.59, 62.28, 61.94, 60.59, 57.89, 53.78, 48.05, 47.81, 51.64, 51.85, 47.2, 48.94, 48.15, 54.02, 48.69, 51.12, 47.74, 58.13, 42.53]
|
[0.89, 0.86, 0.9, 0.82, 0.93, 0.9, 0.91, 0.89, 0.9, 0.93, 0.91, 0.86, 0.91, 0.89, 0.93, 0.9, 0.96, 0.84, 0.59, 0.93, 0.53, 0.91, 0.76, 0.77, 0.97, 0.56, 0.43, 0.64, 0.82, 0.26, 0.47, 0.39, 0.48, 0.53, 0.83, 0.78, 0.63, 0.6, 0.87, 0.68, 0.93, 0.72, 0.91, 0.89, 0.85, 0.78, 0.92, 0.77, 0.79, 0.71, 0.78, 0.72, 0.87, 0.83, 0.82, 0.93, 0.86, 0.95, 0.94, 0.88, 0.87, 0.83, 0.95, 0.99, 1.0, 0.97, 0.94, 0.98, 0.9, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 0.89, 0.87, 0.91, 0.79, 0.94, 1.0, 0.93, 1.0, 0.93, 0.95, 0.94, 0.86, 0.89, 0.91, 0.92, 0.85, 0.77, 0.86, 0.9, 0.9, 0.89, 0.79, 0.81, 0.88, 0.85, 0.84, 0.85, 0.81, 0.92, 0.9, 0.84, 0.84, 0.79, 0.89, 0.86, 0.88, 0.84, 0.81, 0.64, 0.82, 0.74, 0.69, 0.86, 0.69, 0.49, 0.54, 0.65, 0.42, 0.77, 0.61, 0.58, 1.0, 0.91, 0.62, 0.62, 0.28, 0.53, 0.06, 0.4, 0.37, 0.8, 0.58, 0.12, 0.74, 0.82, 0.66, 0.62, 0.82, 0.74, 0.89, 0.83, 0.79, 1.0, 0.82, 0.92, 1.0, 0.93, 0.99, 1.0, 0.96, 0.98, 0.97, 0.97, 0.98, 1.0, 0.97, 0.97, 0.97, 0.97, 0.96, 0.97, 1.0, 0.96, 0.96, 0.86, 0.81, 0.92, 0.76, 0.81, 0.82, 0.8, 0.86, 0.9, 0.87, 0.88, 0.81, 0.84, 0.75, 0.89, 0.83, 0.82, 0.72, 0.82, 0.7, 0.94, 0.84, 0.95, 0.89, 0.94, 0.89, 0.95, 0.93, 0.91, 1.0, 0.84, 0.77, 0.89, 0.88, 0.76, 0.94, 0.82, 0.87, 0.83, 0.86, 0.85, 0.85, 0.94, 0.84, 0.84, 0.92, 0.76, 0.84, 0.79, 0.83, 0.42, 0.71, 0.74, 0.82, 0.65, 0.43, 0.76, 0.9, 0.42, 0.62, 0.68, 0.67, 0.53, 0.46, 0.5, 0.65, 0.52, 0.7, 0.67, 0.84, 0.4, 0.83, 0.81, 0.8, 0.65, 0.84, 0.75, 0.8, 0.78, 0.85, 0.78, 0.9, 0.95, 0.98, 1.0]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 57.866953
| 0.810352
| 2,537
|
O43255
|
Q16656
|
30833558
|
UbiBrowser
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
NRF1
|
MEEHGVTQTEHMATIEAHAVAQQVQQVHVATYTEHSMLSADEDSPSSPEDTSYDDSDILNSTAADEVTAHLAAAGPVGMAAAAAVATGKKRKRPHVFESNPSIRKRQQTRLLRKLRATLDEYTTRVGQQAIVLCISPSKPNPVFKVFGAAPLENVVRKYKSMILEDLESALAEHAPAPQEVNSELPPLTIDGIPVSVDKMTQAQLRAFIPEMLKYSTGRGKPGWGKESCKPIWWPEDIPWANVRSDVRTEEQKQRVSWTQALRTIVKNCYKQHGREDLLYAFEDQQTQTQATATHSIAHLVPSQTVVQTFSNPDGTVSLIQVGTGATVATLADASELPTTVTVAQVNYSAVADGEVEQNWATLQGGEMTIQTTQASEATQAVASLAEAAVAASQEMQQGATVTMALNSEAAAHAVATLAEATLQGGGQIVLSGETAAAVGALTGVQDANGLVQIPVSMYQTVVTSLAQGNGPVQVAMAPVTTRISDSAVTMDGQAVEVVTLEQ
|
Homo sapiens
|
Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '9.8', 'Basal respiratory cells': '3.0', 'Club cells': '4.3', 'Ionocytes': '4.0', 'Mucus glandular cells': '4.7', 'Serous glandular cells': '4.3', 'Gastric mucus-secreting cells': '4.1', 'Proximal enterocytes': '3.4', 'Paneth cells': '7.4', 'Distal enterocytes': '5.0', 'Intestinal goblet cells': '5.9', 'Exocrine glandular cells': '-0.689', 'Basal prostatic cells': '6.0', 'Prostatic glandular cells': '4.5', 'Breast glandular cells': '0.577', 'Breast myoepithelial cells': '0.504', 'Glandular and luminal cells': '4.5', 'Secretory cells': '4.3', 'Basal keratinocytes': '5.3', 'Suprabasal keratinocytes': '6.3', 'Basal squamous epithelial cells': '4.4', 'Squamous epithelial cells': '6.2', 'Alveolar cells type 1': '0.302', 'Alveolar cells type 2': '-0.223', 'Salivary duct cells': '5.8', 'Ductal cells': '0.583', 'Hepatocytes': '-0.076', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.188', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.413', 'Sertoli cells': '0.451', 'Granulosa cells': '6.8', 'Enteroendocrine cells': '8.5', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.484', 'Excitatory neurons': '111.6', 'Inhibitory neurons': '104.9', 'Cone photoreceptor cells': '3.4', 'Rod photoreceptor cells': '8.3', 'Bipolar cells': '9.2', 'Horizontal cells': '10.1', 'Astrocytes': '120.4', 'Oligodendrocyte precursor cells': '134.4', 'Oligodendrocytes': '113.8', 'Microglial cells': '72.5', 'Muller glia cells': '5.0', 'Schwann cells': '0.208', 'Spermatogonia': '0.532', 'Spermatocytes': '0.333', 'Early spermatids': '-0.325', 'Late spermatids': '-0.602', 'Oocytes': '1.5', 'Cytotrophoblasts': '2.6', 'Syncytiotrophoblasts': '3.3', 'Extravillous trophoblasts': '3.8', 'Endothelial cells': '7.3', 'Lymphatic endothelial cells': '6.7', 'Cardiomyocytes': '0.496', 'Skeletal myocytes': '-0.071', 'Smooth muscle cells': '6.3', 'Adipocytes': '6.3', 'Melanocytes': '0.134', 'Fibroblasts': '5.6', 'Peritubular cells': '0.505', 'Endometrial stromal cells': '5.3', 'Ovarian stromal cells': '5.2', 'Undifferentiated cells': '5.2', 'T-cells': '12.6', 'B-cells': '15.5', 'Plasma cells': '9.3', 'Nk-cells': '13.7', 'Granulocytes': '5.2', 'Monocytes': '8.0', 'Macrophages': '6.0', 'Hofbauer cells': '3.5', 'Kupffer cells': '8.3', 'Dendritic cells': '7.9', 'Langerhans cells': '0.264', 'Erythroid cells': '0.164', 'Adipocytes (Subcutaneous)': '-0.328', 'Adipocytes (Visceral)': '-0.268', 'Breast glandular cells (progenitors)': '0.485', 'Adipocytes (Breast)': '-0.466', 'Colon enterocytes': '-0.214', 'Colon enteroendocrine cells': '0.254', 'Enteric glia cells': '0.293', 'Mitotic cells (Colon)': '-0.303', 'Mitotic cells (Heart)': '0.312', 'Podocytes': '-0.152', 'Ascending Loop of Henle cells': '0.499', 'Intercalated cells': '-0.029', 'Cholangiocyte': '0.217', 'NK-cells (Liver)': '0.114', 'Respiratory ciliated cells': '0.251', 'Mitotic cells (Lung)': '-0.246', 'NK-cells (Lung)': '0.317', 'B-cells (Lung)': '0.045', 'Alpha cells': '0.423', 'Beta cells': '0.239', 'Prostate glandular cells': '-0.243', 'Prostate basal glandular cells': '0.199', 'Urothelial cells': '0.251', 'Keratinocyte (other)': '0.340', 'Keratinocyte (granular)': '0.117', 'Hair cortex cells': '-0.144', 'Inner root sheath cells': '-0.133', 'Outer root sheath cells': '-0.042', 'Sebaceous gland cells': '-0.036', 'Eccrine sweat gland cells': '-0.084', 'Adipocytes (Skin)': '-0.154', 'Mitotic cells (Skin)': '0.160', 'Parietal cells': '-0.706', 'Chief cells': '-0.590', 'Gastric mucous cells': '-0.439', 'Gastric enteroendocrine cells': '-0.430', 'Mitotic cells (Stomach)': '-0.002', 'Parafollicular cells': '0.051', 'Thyroid glandular cells': '0.276', 'Mitotic cells (Thyroid)': '-0.091', 'Adrenal cortex cells': '0.231', 'Adrenal medulla cells': '0.023', 'Mitotic cells (Adrenal gland)': '0.007', 'Minor salivary glandular cells': '0.577', 'Minor salivary gland ductal cells': '0.296', 'Minor salivary gland basal cells': '0.192', 'Mitotic cells (Minor salivary gland)': '0.221', 'Adipocytes (Minor salivary gland)': '0.177', 'Somatotropes': '-0.281', 'Lactotropes': '-0.155', 'Gonadotropes': '0.093', 'Corticotropes': '-0.079', 'Thyrotropes': '0.168', 'Undifferentiated cells (Pituitary gland)': '0.479', 'Mitotic cells (Spleen)': '-0.310', 'Platelets': '-0.059', 'Erythrocytes': '-0.030', 'Hematopoietic stem cells': '-0.187', 'B-cells (Spleen)': '0.417', 'NK-cells (Spleen)': '0.317', 'Amygdala excitatory': '171.0', 'Cerebellar inhibitory': '132.0', 'Cge interneuron': '124.3', 'Deep-layer corticothalamic and 6b': '160.5', 'Deep-layer intratelencephalic': '166.0', 'Deep-layer near-projecting': '146.6', 'Eccentric medium spiny neuron': '169.6', 'Hippocampal ca1-3': '150.1', 'Hippocampal ca4': '152.2', 'Hippocampal dentate gyrus': '146.8', 'Lamp5-lhx6 and chandelier': '159.2', 'Lower rhombic lip': '148.2', 'Mammillary body': '182.1', 'Medium spiny neuron': '178.7', 'Mge interneuron': '161.5', 'Midbrain-derived inhibitory': '126.4', 'Miscellaneous': '142.8', 'Splatter': '163.3', 'Thalamic excitatory': '162.4', 'Upper rhombic lip': '158.7', 'Upper-layer intratelencephalic': '163.5', 'Astrocyte': '240.5', 'Bergmann glia': '233.3', 'Central nervous system macrophage': '217.6', 'Choroid plexus epithelial cell': '249.4', 'Committed oligodendrocyte precursor': '162.6', 'Ependymal cell': '258.4', 'Oligodendrocyte': '178.4', 'Oligodendrocyte precursor cell': '220.9', 'Endothelial cell': '132.7', 'Pericyte': '138.0', 'Vascular associated smooth muscle cell': '106.6', 'Fibroblast': '153.2', 'Leukocyte': '181.2', 'Basophil': '57.1', 'Eosinophil': '10.6', 'Neutrophil': '49.0', 'Classical monocyte': '16.0', 'Non-classical monocyte': '21.4', 'Intermediate monocyte': '29.8', 'T-reg': '55.1', 'GdT-cell': '8.2', 'MAIT T-cell': '46.1', 'Memory CD4 T-cell': '6.3', 'Naive CD4 T-cell': '32.8', 'Memory CD8 T-cell': '7.7', 'Naive CD8 T-cell': '30.2', 'Memory B-cell': '5.6', 'Naive B-cell': '26.7', 'Plasmacytoid DC': '30.1', 'Myeloid DC': '26.0', 'NK-cell': '35.9', 'Total PBMC': '37.3', 'Vd2 gdTCR': '46.2', 'Memory CD4 T-cell Th1\\/Th17': '31.2', 'Memory CD4 T-cell Th17': '33.7', 'Memory CD4 T-cell Th2': '35.5', 'Non-Vd2 gdTCR': '53.0', 'Memory CD4 T-cell Th1': '37.4', 'Memory CD4 T-cell TFH': '39.5', 'Terminal effector memory CD4 T-cell': '56.7', 'Central memory CD8 T-cell': '46.5', 'Effector memory CD8 T-cell': '50.7', 'Terminal effector memory CD8 T-cell': '49.6', 'Non-switched memory B-cell': '41.4', 'Plasmablast': '31.6', 'Switched memory B-cell': '45.7', 'Exhausted memory B-cell': '45.4', 'Progenitor cell': '23.9', 'Memory T-reg': '41.6', 'Naive CD4 T-cell activated': '47.7', 'Naive CD8 T-cell activated': '44.7', 'Naive T-reg': '39.6'}
|
8K3D, 8K4L
|
{'Adipose Tissue': 11.569152823920266, 'Adrenal Gland': 6.6473798449612405, 'Bladder': 14.42457142857143, 'Blood': 7.968718191603875, 'Blood Vessel': 14.279647191011238, 'Brain': 9.941648372445115, 'Breast': 12.934908496732024, 'Cervix Uteri': 21.084736842105265, 'Colon': 11.610480102695764, 'Esophagus': 11.158148788927337, 'Fallopian Tube': 20.83111111111111, 'Heart': 5.989803368176538, 'Kidney': 7.4202134831460675, 'Liver': 3.60570796460177, 'Lung': 13.912282006920416, 'Muscle': 8.798434620174346, 'Nerve': 19.240331179321487, 'Ovary': 21.133111111111113, 'Pancreas': 4.182210365853659, 'Pituitary': 14.054480565371025, 'Prostate': 13.926289795918366, 'Salivary Gland': 9.633493827160494, 'Skin': 12.013014372581535, 'Small Intestine': 12.138101604278074, 'Spleen': 15.636464730290456, 'Stomach': 8.009451253481894, 'Testis': 11.436908587257616, 'Thyroid': 17.473558958652376, 'Uterus': 21.46274647887324, 'Vagina': 14.24728205128205}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[47.09, 40.85, 39.56, 43.05, 50.76, 35.34, 43.75, 33.32, 41.12, 35.94, 42.39, 36.99, 39.48, 33.93, 39.83, 37.49, 39.94, 35.65, 36.28, 36.26, 33.7, 34.62, 38.39, 37.18, 35.85, 33.68, 38.12, 36.13, 31.67, 37.94, 32.06, 41.05, 36.72, 37.28, 39.21, 50.97, 43.96, 46.95, 41.18, 45.5, 48.8, 50.92, 44.12, 42.35, 43.48, 36.78, 42.59, 41.43, 34.81, 43.9, 36.48, 38.94, 50.68, 50.46, 56.39, 57.3, 53.01, 53.82, 54.12, 50.61, 48.39, 49.62, 46.67, 52.37, 75.19, 78.24, 80.94, 85.51, 83.97, 82.25, 87.41, 86.2, 83.37, 80.79, 81.5, 85.48, 87.47, 88.28, 89.22, 90.23, 90.98, 90.52, 88.88, 89.35, 87.66, 85.2, 81.7, 76.5, 66.39, 63.78, 61.79, 62.99, 63.4, 77.98, 83.59, 86.55, 88.49, 89.84, 84.82, 85.63, 86.7, 86.76, 89.51, 91.11, 90.43, 92.85, 94.1, 94.07, 95.64, 96.65, 96.13, 96.38, 96.55, 97.43, 97.28, 96.72, 96.97, 97.4, 96.98, 95.88, 96.9, 97.69, 96.64, 94.82, 97.03, 97.11, 95.64, 96.51, 95.99, 96.99, 97.31, 97.47, 96.71, 95.07, 93.53, 89.35, 84.63, 80.43, 73.39, 77.46, 83.94, 89.75, 90.78, 94.85, 95.21, 96.99, 96.8, 96.26, 96.33, 95.39, 95.98, 97.07, 97.37, 97.24, 97.49, 97.45, 96.95, 97.08, 96.96, 95.37, 94.51, 95.93, 95.74, 93.43, 92.15, 93.65, 92.26, 90.1, 90.87, 90.37, 89.18, 86.06, 86.31, 81.45, 78.36, 73.39, 65.87, 59.86, 54.37, 45.06, 46.94, 43.5, 54.33, 69.0, 83.03, 85.1, 82.45, 86.36, 85.57, 83.88, 80.79, 80.33, 84.8, 84.27, 86.2, 87.55, 89.7, 89.03, 87.94, 89.0, 90.83, 93.02, 92.26, 92.25, 94.55, 94.47, 92.44, 93.27, 94.51, 92.05, 90.74, 92.86, 92.98, 90.89, 89.7, 89.45, 88.68, 86.24, 85.04, 81.86, 87.36, 90.38, 91.2, 94.17, 90.64, 92.31, 91.89, 91.31, 92.36, 94.22, 93.0, 93.06, 94.02, 95.56, 94.17, 91.41, 89.32, 93.37, 93.17, 95.15, 94.5, 94.57, 95.15, 92.63, 90.58, 92.95, 93.11, 92.89, 91.63, 90.21, 90.27, 89.83, 92.41, 89.99, 92.1, 91.95, 93.79, 94.94, 94.9, 94.67, 95.72, 96.67, 94.93, 94.97, 95.85, 94.68, 93.98, 94.59, 93.86, 92.11, 91.69, 89.94, 89.07, 85.34, 83.63, 84.34, 79.6, 78.61, 80.51, 65.87, 60.37, 60.35, 55.36, 46.21, 43.93, 44.74, 39.72, 38.09, 39.95, 38.51, 35.58, 34.48, 31.68, 29.15, 28.89, 25.96, 26.02, 24.02, 31.81, 29.18, 29.75, 31.03, 30.51, 35.29, 40.55, 40.52, 38.01, 43.87, 48.84, 51.27, 65.39, 64.61, 53.2, 67.41, 50.1, 55.29, 48.02, 55.3, 48.74, 50.62, 44.7, 39.92, 44.99, 45.36, 40.75, 41.23, 38.57, 46.46, 40.74, 40.62, 37.56, 40.4, 37.79, 37.74, 46.38, 37.11, 34.79, 34.48, 36.84, 33.63, 34.02, 33.0, 32.26, 32.16, 32.42, 33.47, 37.67, 35.35, 32.25, 29.96, 27.53, 30.79, 35.6, 36.3, 28.4, 34.53, 29.46, 35.95, 37.29, 38.92, 33.95, 35.54, 32.92, 32.13, 30.24, 32.88, 27.32, 28.35, 29.02, 29.75, 26.94, 27.61, 26.46, 27.82, 27.16, 30.04, 29.76, 32.01, 31.02, 30.87, 28.3, 29.72, 28.78, 29.39, 30.53, 31.17, 30.08, 29.0, 30.77, 32.76, 30.36, 29.66, 29.47, 27.5, 25.35, 25.4, 26.24, 24.98, 23.07, 23.7, 23.76, 24.05, 23.74, 22.79, 22.4, 25.89, 26.14, 28.32, 29.87, 31.78, 30.15, 30.39, 33.55, 30.98, 31.73, 32.77, 34.25, 32.22, 34.61, 33.29, 28.14, 33.87, 36.04, 36.45, 41.96, 48.06, 54.85, 59.68, 57.81, 66.14, 63.77, 68.74, 71.92, 63.42, 61.91, 66.79, 67.19, 67.33, 64.19, 68.84, 68.99, 62.55, 59.93, 64.54, 61.67, 62.61, 66.24, 69.22, 69.5, 70.6, 64.29, 68.25, 70.4, 59.53, 66.18, 57.56, 61.73, 63.67, 63.49, 66.82, 65.45, 64.11, 65.98, 60.72, 58.11, 63.64, 61.68, 55.84, 43.47, 40.03, 47.16, 36.59, 34.6, 31.47, 29.4, 27.35, 26.43, 25.1, 27.25, 29.94, 25.75, 29.38, 27.21, 28.74, 33.08, 29.55, 34.63, 29.65, 31.78, 33.12, 32.68, 32.63, 33.37, 31.91, 31.29, 31.86, 25.62, 31.92, 31.7, 29.51, 35.88, 29.1, 40.11]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.94, 0.99, 0.99, 1.0, 1.0, 0.96, 0.89, 0.98, 0.86, 0.97, 0.95, 0.98, 1.0, 0.98, 0.98, 1.0, 0.98, 0.93, 0.88, 0.93, 0.85, 0.85, 0.73, 0.89, 0.9, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 0.91, 0.96, 0.82, 0.89, 0.93, 0.92, 0.91, 0.98, 0.89, 0.9, 0.77, 0.55, 0.5, 0.49, 0.54, 0.14, 0.41, 0.68, 0.48, 0.17, 0.83, 0.82, 0.25, 0.56, 0.27, 0.02, 0.4, 0.45, 0.0, 0.1, 0.63, 0.34, 0.19, 0.32, 0.1, 0.0, 0.06, 0.2, 0.14, 0.0, 0.28, 0.57, 0.16, 0.16, 0.44, 0.4, 0.54, 0.6, 0.66, 0.96, 0.65, 0.94, 0.85, 0.91, 0.28, 0.28, 0.21, 0.16, 0.15, 0.45, 0.44, 0.23, 0.58, 0.77, 0.31, 0.34, 0.61, 0.54, 0.54, 0.17, 0.76, 0.62, 0.45, 0.47, 0.54, 0.61, 0.12, 0.43, 0.5, 0.43, 0.23, 0.83, 0.8, 0.51, 0.74, 0.52, 0.55, 0.17, 0.28, 0.18, 0.39, 0.28, 0.31, 0.22, 0.07, 0.04, 0.75, 0.91, 0.78, 0.47, 0.3, 0.15, 0.33, 0.07, 0.06, 0.35, 0.11, 0.54, 0.62, 0.31, 0.19, 0.61, 0.52, 0.15, 0.44, 0.87, 0.48, 0.41, 0.61, 0.56, 0.29, 0.15, 0.64, 0.6, 0.3, 0.26, 0.6, 0.45, 0.11, 0.48, 0.86, 0.54, 0.2, 0.49, 0.82, 0.88, 0.76, 0.9, 0.47, 0.86, 0.41, 0.6, 0.05, 0.03, 0.65, 0.08, 0.39, 0.21, 0.68, 0.21, 0.18, 0.14, 0.03, 0.03, 0.0, 0.29, 0.41, 0.05, 0.37, 0.35, 0.51, 0.23, 0.0, 0.24, 0.63, 0.08, 0.0, 0.36, 0.5, 0.0, 0.01, 0.6, 0.49, 0.27, 0.35, 0.76, 0.39, 0.8, 0.87, 0.16, 0.3, 0.28, 0.73, 0.61, 0.62, 0.83, 0.16, 0.27, 0.14, 0.86, 0.12, 0.04, 0.08, 0.89, 0.61, 0.01, 0.4, 0.07, 0.22, 0.39, 0.01, 0.74, 0.46, 0.25, 0.55, 0.06, 0.59, 0.63, 0.67, 0.37, 0.34, 0.74, 0.81, 0.37, 0.63, 0.12, 0.24, 0.49, 0.02, 0.0, 0.12, 0.32, 0.0, 0.0, 0.28, 0.32, 0.0, 0.0, 0.61, 0.61, 0.22, 0.7, 0.31, 0.43, 0.66, 0.33, 0.03, 0.53, 0.3, 0.23, 0.39, 0.6, 0.55, 0.85, 0.69, 0.61, 0.81, 0.9, 0.75, 0.86, 0.89, 0.82, 1.0, 0.76, 1.0, 0.84, 0.98, 0.95, 0.93, 0.88, 0.9, 0.95, 0.55, 0.61, 0.51, 0.52, 0.68, 0.34, 0.81, 0.31, 0.98, 0.7, 0.48, 0.09, 0.24, 0.1, 0.14, 0.29, 0.32, 0.53, 0.96, 0.62, 0.77, 0.44, 0.57, 0.35, 0.11, 0.49, 0.27, 0.77, 0.64, 0.52, 0.86, 0.92, 0.52, 0.67, 0.65, 0.58, 0.22, 0.62, 0.13, 0.6, 0.57, 0.18, 0.28, 0.52, 0.69, 0.39, 0.77, 0.66, 0.94, 0.8, 0.75, 0.67, 0.62, 0.65, 0.31, 0.62, 0.3, 0.62, 0.38, 0.92, 0.94, 0.53, 0.8, 0.43, 0.64, 0.37, 0.81, 0.62, 0.8, 0.88, 0.89, 0.85, 0.87, 0.68, 0.68, 0.83, 0.78, 0.64, 0.35, 0.76, 0.82, 0.47, 0.71, 0.75, 0.72, 0.67, 0.81, 0.86, 0.76, 0.96, 0.99, 1.0, 1.0, 1.0, 0.99, 0.9, 0.88, 0.8, 0.78, 0.69, 0.88, 0.61, 0.91, 0.9, 0.9, 0.62, 0.36, 0.72, 0.79, 0.54, 0.33, 0.56, 0.68, 0.64, 0.74, 0.8, 0.46, 0.88, 0.68, 0.95, 0.84, 0.79, 0.29, 0.56, 0.24, 0.57, 0.09, 0.51, 0.64, 0.83, 0.45, 0.0, 0.5, 0.33, 0.01, 0.1, 0.67, 0.12, 0.21, 0.77, 0.43, 0.56, 0.47, 0.99, 0.77, 0.3, 0.33, 0.0, 0.51, 0.01, 0.33, 0.42, 0.79, 0.19, 0.27, 0.67, 0.54, 0.1, 0.39, 0.42, 0.13, 0.42, 0.81, 0.65, 0.77, 0.64, 0.72, 0.76, 0.31, 0.94, 0.32, 0.94, 0.61, 0.83, 0.85, 0.81, 0.77, 0.77, 0.86, 0.8, 0.91, 0.9, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.96, 0.88, 0.99, 0.91, 1.0, 1.0]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 61.186342
| 0.565368
| 1,574
|
O43255
|
Q16665
|
22055192
|
UbiNet, UbiBrowser
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
HIF1A
|
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDAGDLDIEDDMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECVLKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYNDVMLPSPNEKLQNINLAMSPLPTAETPKPLRSSADPALNQEVALKLEPNPESLELSFTMPQIQDQTPSPSDGSTRQSSPEPNSPSEYCFYVDSDMVNEFKLELVEKLFAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPESASPQSTVTVFQQTQIQEPTANATTTTATTDELKTVTKDRMEDIKILIASPSPTHIHKETTSATSSPYRDTQSRTASPNRAGKGVIEQTEKSHPRSPNVLSVALSQRTTVPEEELNPKILALQNAQRKRKMEHDGSLFQAVGIGTLLQQPDDHAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
|
Homo sapiens
|
Cytoplasm, Nucleus, Nucleus speckle
|
Tissue enhanced (bone)
|
{'Ciliated cells': '57.6', 'Basal respiratory cells': '96.6', 'Club cells': '49.2', 'Ionocytes': '43.1', 'Mucus glandular cells': '128.0', 'Serous glandular cells': '51.8', 'Gastric mucus-secreting cells': '49.5', 'Proximal enterocytes': '16.3', 'Paneth cells': '16.4', 'Distal enterocytes': '32.5', 'Intestinal goblet cells': '37.0', 'Exocrine glandular cells': '-0.630', 'Basal prostatic cells': '195.3', 'Prostatic glandular cells': '39.0', 'Breast glandular cells': '0.139', 'Breast myoepithelial cells': '0.329', 'Glandular and luminal cells': '275.6', 'Secretory cells': '217.4', 'Basal keratinocytes': '102.6', 'Suprabasal keratinocytes': '103.0', 'Basal squamous epithelial cells': '101.3', 'Squamous epithelial cells': '129.7', 'Alveolar cells type 1': '-0.212', 'Alveolar cells type 2': '-0.123', 'Salivary duct cells': '75.7', 'Ductal cells': '0.717', 'Hepatocytes': '0.345', 'Cholangiocytes': '78.2', 'Proximal tubular cells': '0.153', 'Distal tubular cells': '135.2', 'Collecting duct cells': '260.6', 'Mesothelial cells': '-0.038', 'Sertoli cells': '0.566', 'Granulosa cells': '101.6', 'Enteroendocrine cells': '59.2', 'Pancreatic endocrine cells': '198.7', 'Leydig cells': '0.670', 'Excitatory neurons': '44.0', 'Inhibitory neurons': '37.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '46.7', 'Bipolar cells': '46.3', 'Horizontal cells': '66.1', 'Astrocytes': '65.6', 'Oligodendrocyte precursor cells': '74.1', 'Oligodendrocytes': '33.3', 'Microglial cells': '51.0', 'Muller glia cells': '115.4', 'Schwann cells': '-0.046', 'Spermatogonia': '0.602', 'Spermatocytes': '0.351', 'Early spermatids': '-0.445', 'Late spermatids': '-0.640', 'Oocytes': '61.0', 'Cytotrophoblasts': '24.5', 'Syncytiotrophoblasts': '24.3', 'Extravillous trophoblasts': '68.2', 'Endothelial cells': '122.0', 'Lymphatic endothelial cells': '142.6', 'Cardiomyocytes': '0.506', 'Skeletal myocytes': '-0.124', 'Smooth muscle cells': '94.7', 'Adipocytes': '91.5', 'Melanocytes': '0.114', 'Fibroblasts': '95.9', 'Peritubular cells': '0.375', 'Endometrial stromal cells': '137.5', 'Ovarian stromal cells': '27.4', 'Undifferentiated cells': '36.8', 'T-cells': '84.3', 'B-cells': '146.5', 'Plasma cells': '50.4', 'Nk-cells': '75.4', 'Granulocytes': '222.5', 'Monocytes': '270.8', 'Macrophages': '279.6', 'Hofbauer cells': '187.0', 'Kupffer cells': '145.6', 'Dendritic cells': '33.3', 'Langerhans cells': '-0.076', 'Erythroid cells': '-0.044', 'Adipocytes (Subcutaneous)': '-0.406', 'Adipocytes (Visceral)': '-0.184', 'Breast glandular cells (progenitors)': '-0.008', 'Adipocytes (Breast)': '-0.347', 'Colon enterocytes': '0.040', 'Colon enteroendocrine cells': '0.139', 'Enteric glia cells': '-0.090', 'Mitotic cells (Colon)': '0.326', 'Mitotic cells (Heart)': '0.519', 'Podocytes': '-0.135', 'Ascending Loop of Henle cells': '0.156', 'Intercalated cells': '-0.251', 'Cholangiocyte': '0.380', 'NK-cells (Liver)': '-0.291', 'Respiratory ciliated cells': '-0.089', 'Mitotic cells (Lung)': '0.080', 'NK-cells (Lung)': '0.083', 'B-cells (Lung)': '0.155', 'Alpha cells': '0.333', 'Beta cells': '0.192', 'Prostate glandular cells': '-0.273', 'Prostate basal glandular cells': '0.007', 'Urothelial cells': '0.104', 'Keratinocyte (other)': '-0.100', 'Keratinocyte (granular)': '-0.451', 'Hair cortex cells': '0.273', 'Inner root sheath cells': '0.345', 'Outer root sheath cells': '0.496', 'Sebaceous gland cells': '0.000', 'Eccrine sweat gland cells': '0.450', 'Adipocytes (Skin)': '0.066', 'Mitotic cells (Skin)': '0.371', 'Parietal cells': '-0.466', 'Chief cells': '-0.381', 'Gastric mucous cells': '-0.107', 'Gastric enteroendocrine cells': '-0.196', 'Mitotic cells (Stomach)': '0.229', 'Parafollicular cells': '0.075', 'Thyroid glandular cells': '0.095', 'Mitotic cells (Thyroid)': '0.116', 'Adrenal cortex cells': '0.398', 'Adrenal medulla cells': '-0.014', 'Mitotic cells (Adrenal gland)': '0.239', 'Minor salivary glandular cells': '0.422', 'Minor salivary gland ductal cells': '-0.120', 'Minor salivary gland basal cells': '0.537', 'Mitotic cells (Minor salivary gland)': '0.606', 'Adipocytes (Minor salivary gland)': '0.072', 'Somatotropes': '-0.306', 'Lactotropes': '-0.328', 'Gonadotropes': '-0.118', 'Corticotropes': '-0.019', 'Thyrotropes': '0.098', 'Undifferentiated cells (Pituitary gland)': '0.336', 'Mitotic cells (Spleen)': '-0.198', 'Platelets': '-0.132', 'Erythrocytes': '-0.252', 'Hematopoietic stem cells': '-0.178', 'B-cells (Spleen)': '0.185', 'NK-cells (Spleen)': '0.157', 'Amygdala excitatory': '62.7', 'Cerebellar inhibitory': '67.0', 'Cge interneuron': '67.2', 'Deep-layer corticothalamic and 6b': '64.8', 'Deep-layer intratelencephalic': '66.6', 'Deep-layer near-projecting': '52.7', 'Eccentric medium spiny neuron': '73.0', 'Hippocampal ca1-3': '62.1', 'Hippocampal ca4': '79.3', 'Hippocampal dentate gyrus': '69.4', 'Lamp5-lhx6 and chandelier': '56.5', 'Lower rhombic lip': '75.8', 'Mammillary body': '61.2', 'Medium spiny neuron': '70.5', 'Mge interneuron': '47.2', 'Midbrain-derived inhibitory': '90.2', 'Miscellaneous': '58.0', 'Splatter': '54.5', 'Thalamic excitatory': '77.7', 'Upper rhombic lip': '119.1', 'Upper-layer intratelencephalic': '57.4', 'Astrocyte': '279.9', 'Bergmann glia': '305.3', 'Central nervous system macrophage': '455.1', 'Choroid plexus epithelial cell': '138.0', 'Committed oligodendrocyte precursor': '91.4', 'Ependymal cell': '50.4', 'Oligodendrocyte': '54.4', 'Oligodendrocyte precursor cell': '119.2', 'Endothelial cell': '209.9', 'Pericyte': '224.2', 'Vascular associated smooth muscle cell': '164.2', 'Fibroblast': '77.0', 'Leukocyte': '281.9', 'Basophil': '138.6', 'Eosinophil': '155.1', 'Neutrophil': '789.9', 'Classical monocyte': '1005.8', 'Non-classical monocyte': '263.6', 'Intermediate monocyte': '155.5', 'T-reg': '85.3', 'GdT-cell': '11.5', 'MAIT T-cell': '80.4', 'Memory CD4 T-cell': '15.0', 'Naive CD4 T-cell': '270.4', 'Memory CD8 T-cell': '13.3', 'Naive CD8 T-cell': '192.8', 'Memory B-cell': '19.6', 'Naive B-cell': '669.8', 'Plasmacytoid DC': '100.0', 'Myeloid DC': '181.6', 'NK-cell': '104.4', 'Total PBMC': '142.3', 'Vd2 gdTCR': '96.5', 'Memory CD4 T-cell TFH': '170.1', 'Memory CD4 T-cell Th2': '164.1', 'Memory CD4 T-cell Th17': '168.6', 'Memory CD4 T-cell Th1\\/Th17': '223.4', 'Non-Vd2 gdTCR': '84.5', 'Memory CD4 T-cell Th1': '191.6', 'Terminal effector memory CD4 T-cell': '85.8', 'Central memory CD8 T-cell': '97.2', 'Effector memory CD8 T-cell': '81.6', 'Terminal effector memory CD8 T-cell': '83.7', 'Switched memory B-cell': '110.3', 'Plasmablast': '67.9', 'Non-switched memory B-cell': '113.3', 'Exhausted memory B-cell': '113.1', 'Progenitor cell': '108.6', 'Naive CD4 T-cell activated': '724.5', 'Naive CD8 T-cell activated': '440.0', 'Memory T-reg': '85.6', 'Naive T-reg': '191.7'}
|
1H2K, 1H2L, 1H2M, 1L3E, 1L8C, 1LM8, 1LQB, 2ILM, 3HQR, 3HQU, 4AJY, 4H6J, 5JWP, 5L9B, 5L9V, 5LA9, 5LAS, 6GFX, 6GMR, 6YW3, 7LVS, 7QGS, 8HE0, 8HE3
|
{'Adipose Tissue': 91.02975913621265, 'Adrenal Gland': 160.4879457364341, 'Bladder': 72.26761904761904, 'Blood': 84.43241119483316, 'Blood Vessel': 99.6728988764045, 'Brain': 31.575569265707795, 'Breast': 65.82370370370371, 'Cervix Uteri': 71.56947368421052, 'Colon': 43.61186136071887, 'Esophagus': 70.6802276816609, 'Fallopian Tube': 91.62777777777778, 'Heart': 26.260513588850177, 'Kidney': 76.36101123595506, 'Liver': 21.700778761061947, 'Lung': 155.54134948096885, 'Muscle': 9.722001245330013, 'Nerve': 55.99071082390953, 'Ovary': 74.43405555555555, 'Pancreas': 16.31711280487805, 'Pituitary': 60.628197879858654, 'Prostate': 60.55591836734693, 'Salivary Gland': 71.3070987654321, 'Skin': 181.8585903814262, 'Small Intestine': 57.1179679144385, 'Spleen': 78.34730290456432, 'Stomach': 41.65272980501393, 'Testis': 40.81313019390582, 'Thyroid': 94.75473200612556, 'Uterus': 59.57866197183099, 'Vagina': 83.23775641025641}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
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|
[47.56, 55.35, 57.25, 56.78, 55.33, 58.95, 60.16, 62.74, 66.58, 72.33, 74.15, 75.37, 79.04, 84.44, 86.56, 89.63, 88.75, 90.45, 93.31, 92.56, 95.0, 94.68, 95.63, 96.56, 96.94, 97.14, 97.75, 97.35, 97.9, 96.8, 96.82, 97.43, 96.33, 95.5, 96.01, 96.54, 95.76, 93.13, 94.92, 95.63, 95.15, 93.16, 93.96, 92.73, 90.04, 88.81, 89.47, 88.68, 89.15, 88.8, 89.26, 89.13, 89.55, 92.19, 93.8, 95.21, 95.91, 95.33, 96.14, 96.69, 96.29, 95.93, 96.51, 95.64, 95.07, 93.77, 93.41, 91.45, 90.18, 87.6, 85.67, 82.45, 78.74, 73.03, 63.05, 57.6, 54.23, 58.19, 54.8, 57.3, 60.43, 66.69, 69.6, 68.28, 70.22, 70.6, 71.34, 77.27, 78.83, 78.9, 87.97, 91.2, 90.9, 90.77, 92.99, 93.33, 92.31, 95.33, 97.42, 97.42, 97.76, 97.01, 97.0, 94.05, 92.23, 92.81, 95.08, 96.44, 97.58, 95.82, 96.45, 97.0, 95.6, 92.58, 94.6, 96.0, 93.45, 93.1, 93.69, 95.18, 93.77, 94.08, 93.49, 94.27, 91.24, 92.95, 95.93, 96.85, 95.45, 97.17, 97.41, 97.82, 97.88, 97.13, 97.17, 97.92, 97.63, 97.37, 96.55, 97.07, 97.4, 95.7, 94.77, 95.05, 95.0, 93.41, 92.85, 92.58, 86.48, 77.39, 66.51, 57.47, 45.07, 42.51, 48.78, 47.85, 40.37, 50.98, 48.81, 52.73, 61.77, 74.47, 90.49, 93.2, 93.88, 94.43, 95.57, 97.34, 97.02, 97.74, 97.11, 96.91, 95.88, 95.85, 92.83, 88.07, 80.44, 81.24, 81.35, 88.03, 90.02, 91.17, 91.26, 90.05, 91.73, 93.13, 93.53, 93.59, 94.88, 95.58, 97.17, 97.6, 97.6, 97.67, 97.14, 96.17, 94.37, 92.41, 87.88, 85.9, 77.82, 69.01, 59.22, 53.9, 52.7, 50.54, 47.28, 50.68, 54.12, 54.48, 54.51, 57.26, 59.07, 63.96, 67.72, 75.66, 80.31, 88.8, 92.35, 95.26, 95.8, 97.81, 98.09, 98.2, 96.74, 94.74, 92.96, 87.21, 88.15, 85.28, 82.4, 79.47, 78.12, 68.54, 72.86, 75.98, 81.54, 85.96, 89.18, 92.2, 93.84, 94.22, 94.42, 96.43, 97.18, 97.75, 97.05, 95.67, 95.68, 96.76, 97.81, 97.76, 97.06, 96.79, 95.09, 92.3, 93.6, 92.38, 94.76, 94.88, 93.99, 94.51, 94.01, 93.5, 95.23, 95.47, 95.29, 94.91, 93.85, 95.24, 96.32, 95.54, 95.96, 96.29, 96.21, 95.79, 94.19, 95.34, 96.28, 96.42, 94.04, 95.83, 96.88, 91.54, 92.88, 94.36, 96.69, 95.57, 95.0, 96.39, 96.05, 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|
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|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 60.301138
| 0.640581
| 688
|
O43255
|
Q7Z6J0
| null |
degron_data
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
SH3RF1
|
MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVEELPSNILLVRLLDGIKQRPWKPGPGGGSGTNCTNALRSQSSTVANCSSKDLQSSQGGQQPRVQSWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGIHGFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDKPPVPGVDAGECSSAAAQSSTAPKHSDTKKNTKKRHSFTSLTMANKSSQASQNRHSMEISPPVLISSSNPTAAARISELSGLSCSAPSQVHISTTGLIVTPPPSSPVTTGPSFTFPSDVPYQAALGTLNPPLPPPPLLAATVLASTPPGATAAAAAAGMGPRPMAGSTDQIAHLRPQTRPSVYVAIYPYTPRKEDELELRKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYVAPVTRAVTNASQAKVPMSTAGQTSRGVTMVSPSTAGGPAQKLQGNGVAGSPSVVPAAVVSAAHIQTSPQAKVLLHMTGQMTVNQARNAVRTVAAHNQERPTAAVTPIQVQNAAGLSPASVGLSHHSLASPQPAPLMPGSATHTAAISISRASAPLACAAAAPLTSPSITSASLEAEPSGRIVTVLPGLPTSPDSASSACGNSSATKPDKDSKKEKKGLLKLLSGASTKRKPRVSPPASPTLEVELGSAELPLQGAVGPELPPGGGHGRAGSCPVDGDGPVTTAVAGAALAQDAFHRKASSLDSAVPIAPPPRQACSSLGPVLNESRPVVCERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI
|
Homo sapiens
|
Cytoplasm, perinuclear region, Cell projection, lamellipodium, Golgi apparatus, trans-Golgi network
|
Low tissue specificity
|
{'Ciliated cells': '25.6', 'Basal respiratory cells': '11.1', 'Club cells': '22.2', 'Ionocytes': '16.2', 'Mucus glandular cells': '68.1', 'Serous glandular cells': '33.3', 'Gastric mucus-secreting cells': '73.7', 'Proximal enterocytes': '25.3', 'Paneth cells': '23.0', 'Distal enterocytes': '52.9', 'Intestinal goblet cells': '34.2', 'Exocrine glandular cells': '-0.626', 'Basal prostatic cells': '18.8', 'Prostatic glandular cells': '79.6', 'Breast glandular cells': '0.497', 'Breast myoepithelial cells': '0.541', 'Glandular and luminal cells': '39.4', 'Secretory cells': '17.0', 'Basal keratinocytes': '25.4', 'Suprabasal keratinocytes': '15.4', 'Basal squamous epithelial cells': '11.3', 'Squamous epithelial cells': '8.7', 'Alveolar cells type 1': '0.586', 'Alveolar cells type 2': '0.114', 'Salivary duct cells': '50.9', 'Ductal cells': '0.714', 'Hepatocytes': '0.297', 'Cholangiocytes': '36.2', 'Proximal tubular cells': '0.293', 'Distal tubular cells': '9.2', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.350', 'Sertoli cells': '0.681', 'Granulosa cells': '13.2', 'Enteroendocrine cells': '32.8', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.536', 'Excitatory neurons': '53.0', 'Inhibitory neurons': '52.6', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.6', 'Bipolar cells': '4.5', 'Horizontal cells': '6.9', 'Astrocytes': '138.7', 'Oligodendrocyte precursor cells': '84.0', 'Oligodendrocytes': '198.3', 'Microglial cells': '50.1', 'Muller glia cells': '11.8', 'Schwann cells': '0.196', 'Spermatogonia': '0.505', 'Spermatocytes': '0.278', 'Early spermatids': '-0.328', 'Late spermatids': '-0.605', 'Oocytes': '2.2', 'Cytotrophoblasts': '12.9', 'Syncytiotrophoblasts': '11.6', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '13.1', 'Lymphatic endothelial cells': '4.9', 'Cardiomyocytes': '0.384', 'Skeletal myocytes': '-0.172', 'Smooth muscle cells': '27.9', 'Adipocytes': '24.2', 'Melanocytes': '0.110', 'Fibroblasts': '15.6', 'Peritubular cells': '0.424', 'Endometrial stromal cells': '13.2', 'Ovarian stromal cells': '13.9', 'Undifferentiated cells': '26.8', 'T-cells': '1.0', 'B-cells': '3.0', 'Plasma cells': '4.2', 'Nk-cells': '0.1', 'Granulocytes': '6.6', 'Monocytes': '6.9', 'Macrophages': '10.9', 'Hofbauer cells': '7.4', 'Kupffer cells': '6.3', 'Dendritic cells': '2.0', 'Langerhans cells': '0.014', 'Erythroid cells': '0.108', 'Adipocytes (Subcutaneous)': '-0.170', 'Adipocytes (Visceral)': '-0.332', 'Breast glandular cells (progenitors)': '0.291', 'Adipocytes (Breast)': '-0.583', 'Colon enterocytes': '0.189', 'Colon enteroendocrine cells': '0.120', 'Enteric glia cells': '0.131', 'Mitotic cells (Colon)': '0.244', 'Mitotic cells (Heart)': '0.457', 'Podocytes': '0.233', 'Ascending Loop of Henle cells': '0.241', 'Intercalated cells': '0.259', 'Cholangiocyte': '0.201', 'NK-cells (Liver)': '0.019', 'Respiratory ciliated cells': '0.093', 'Mitotic cells (Lung)': '-0.156', 'NK-cells (Lung)': '0.274', 'B-cells (Lung)': '0.016', 'Alpha cells': '0.383', 'Beta cells': '0.219', 'Prostate glandular cells': '0.622', 'Prostate basal glandular cells': '0.454', 'Urothelial cells': '0.034', 'Keratinocyte (other)': '-0.077', 'Keratinocyte (granular)': '-0.460', 'Hair cortex cells': '0.244', 'Inner root sheath cells': '0.302', 'Outer root sheath cells': '0.527', 'Sebaceous gland cells': '0.014', 'Eccrine sweat gland cells': '0.427', 'Adipocytes (Skin)': '0.022', 'Mitotic cells (Skin)': '0.315', 'Parietal cells': '0.062', 'Chief cells': '0.022', 'Gastric mucous cells': '0.490', 'Gastric enteroendocrine cells': '0.154', 'Mitotic cells (Stomach)': '0.452', 'Parafollicular cells': '0.178', 'Thyroid glandular cells': '0.507', 'Mitotic cells (Thyroid)': '-0.049', 'Adrenal cortex cells': '0.275', 'Adrenal medulla cells': '0.023', 'Mitotic cells (Adrenal gland)': '0.132', 'Minor salivary glandular cells': '0.410', 'Minor salivary gland ductal cells': '0.389', 'Minor salivary gland basal cells': '-0.077', 'Mitotic cells (Minor salivary gland)': '-0.208', 'Adipocytes (Minor salivary gland)': '-0.108', 'Somatotropes': '-0.146', 'Lactotropes': '-0.232', 'Gonadotropes': '0.168', 'Corticotropes': '-0.257', 'Thyrotropes': '0.060', 'Undifferentiated cells (Pituitary gland)': '0.438', 'Mitotic cells (Spleen)': '-0.131', 'Platelets': '-0.048', 'Erythrocytes': '-0.068', 'Hematopoietic stem cells': '-0.231', 'B-cells (Spleen)': '0.180', 'NK-cells (Spleen)': '0.257', 'Amygdala excitatory': '86.8', 'Cerebellar inhibitory': '56.6', 'Cge interneuron': '59.0', 'Deep-layer corticothalamic and 6b': '97.9', 'Deep-layer intratelencephalic': '77.1', 'Deep-layer near-projecting': '176.6', 'Eccentric medium spiny neuron': '43.6', 'Hippocampal ca1-3': '249.8', 'Hippocampal ca4': '191.9', 'Hippocampal dentate gyrus': '39.3', 'Lamp5-lhx6 and chandelier': '65.7', 'Lower rhombic lip': '73.0', 'Mammillary body': '82.2', 'Medium spiny neuron': '72.1', 'Mge interneuron': '74.6', 'Midbrain-derived inhibitory': '42.2', 'Miscellaneous': '104.3', 'Splatter': '63.1', 'Thalamic excitatory': '67.2', 'Upper rhombic lip': '8.2', 'Upper-layer intratelencephalic': '66.2', 'Astrocyte': '165.8', 'Bergmann glia': '263.2', 'Central nervous system macrophage': '69.9', 'Choroid plexus epithelial cell': '79.6', 'Committed oligodendrocyte precursor': '103.9', 'Ependymal cell': '121.7', 'Oligodendrocyte': '261.5', 'Oligodendrocyte precursor cell': '167.5', 'Endothelial cell': '64.0', 'Pericyte': '748.4', 'Vascular associated smooth muscle cell': '279.2', 'Fibroblast': '235.9', 'Leukocyte': '25.0', 'Basophil': '0.2', 'Eosinophil': '0.0', 'Neutrophil': '0.6', 'Classical monocyte': '7.8', 'Non-classical monocyte': '34.9', 'Intermediate monocyte': '30.9', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.3', 'Naive B-cell': '1.3', 'Plasmacytoid DC': '8.5', 'Myeloid DC': '15.6', 'NK-cell': '0.6', 'Total PBMC': '4.4', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '1.7', 'Plasmablast': '17.6', 'Switched memory B-cell': '4.9', 'Exhausted memory B-cell': '10.0', 'Progenitor cell': '10.1', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
|
7NZC, 7NZD
|
{'Adipose Tissue': 16.55268106312292, 'Adrenal Gland': 3.9053914728682178, 'Bladder': 13.04295238095238, 'Blood': 3.0890450893433803, 'Blood Vessel': 17.826579775280898, 'Brain': 8.241760295230886, 'Breast': 15.71548366013072, 'Cervix Uteri': 9.19657894736842, 'Colon': 11.278784338896022, 'Esophagus': 7.288459515570935, 'Fallopian Tube': 9.644555555555556, 'Heart': 4.474848199767712, 'Kidney': 9.531640449438203, 'Liver': 4.087484513274337, 'Lung': 15.784787197231834, 'Muscle': 7.770714819427148, 'Nerve': 14.890922455573506, 'Ovary': 17.466016666666665, 'Pancreas': 5.113128048780488, 'Pituitary': 7.614703180212014, 'Prostate': 18.3228693877551, 'Salivary Gland': 23.1078024691358, 'Skin': 12.126257048092867, 'Small Intestine': 9.717994652406418, 'Spleen': 4.110323651452282, 'Stomach': 12.75916713091922, 'Testis': 10.850764542936288, 'Thyroid': 22.719093415007656, 'Uterus': 9.208640845070422, 'Vagina': 9.737910256410256}
|
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|
[0.77, 0.71, 0.36, 0.55, 0.29, 0.21, 0.26, 0.34, 0.73, 0.1, 0.45, 0.01, 0.48, 0.46, 0.4, 0.66, 0.44, 0.52, 0.08, 0.49, 0.5, 0.31, 0.01, 0.09, 0.16, 0.02, 0.66, 0.23, 0.77, 0.33, 0.19, 0.01, 0.17, 0.25, 0.71, 0.14, 0.0, 0.45, 0.46, 0.17, 0.33, 0.76, 0.74, 0.73, 0.82, 0.31, 0.05, 0.42, 0.03, 0.39, 0.56, 0.44, 0.75, 0.41, 0.59, 0.07, 0.95, 0.38, 0.52, 0.07, 0.61, 0.7, 0.06, 0.63, 0.34, 0.21, 0.24, 0.71, 0.05, 0.35, 0.42, 0.38, 0.14, 0.45, 0.58, 0.14, 0.82, 0.68, 0.69, 0.87, 0.86, 0.94, 0.88, 0.86, 0.97, 0.86, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.9, 0.98, 0.86, 0.98, 0.93, 0.99, 0.76, 0.93, 0.94, 0.97, 0.82, 0.88, 0.39, 0.82, 0.58, 0.15, 0.02, 0.0, 0.45, 0.02, 0.38, 0.64, 0.58, 0.08, 0.77, 0.32, 0.87, 0.78, 0.99, 0.43, 0.12, 0.0, 0.64, 0.06, 0.58, 0.68, 0.44, 0.3, 0.51, 0.0, 0.22, 0.05, 0.56, 0.75, 0.4, 0.58, 0.46, 0.8, 0.73, 0.38, 0.09, 0.24, 0.0, 0.24, 0.09, 0.92, 0.53, 0.64, 0.6, 0.03, 0.42, 0.0, 0.12, 0.21, 0.76, 0.29, 0.1, 0.47, 0.31, 0.54, 0.44, 0.54, 0.22, 0.86, 0.77, 0.66, 0.56, 0.28, 0.3, 0.01, 0.43, 0.01, 0.43, 0.63, 0.57, 0.14, 0.69, 0.25, 0.79, 0.7, 0.79, 0.71, 0.33, 0.47, 0.71, 0.66, 0.18, 0.02, 0.45, 0.08, 0.51, 0.61, 0.55, 0.31, 0.53, 0.0, 0.32, 0.04, 0.42, 0.47, 0.17, 0.43, 0.44, 0.63, 0.7, 0.33, 0.0, 0.19, 0.0, 0.37, 0.25, 0.78, 0.92, 0.67, 0.55, 0.06, 0.25, 0.0, 0.11, 0.18, 0.75, 0.37, 0.06, 0.58, 0.16, 0.3, 0.67, 0.21, 0.0, 0.54, 0.61, 0.37, 0.13, 0.74, 0.72, 0.57, 0.61, 0.82, 0.91, 0.82, 0.93, 0.88, 0.93, 0.96, 0.93, 0.99, 0.99, 0.86, 0.99, 0.82, 1.0, 0.97, 1.0, 0.96, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.83, 0.95, 0.6, 0.95, 0.92, 0.98, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.85, 0.89, 0.86, 0.88, 0.88, 0.86, 0.87, 0.73, 0.92, 0.79, 0.83, 0.89, 0.72, 0.9, 0.9, 0.92, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 1.0, 0.9, 0.99, 0.99, 0.99, 1.0, 0.89, 1.0, 0.84, 1.0, 0.92, 1.0, 1.0, 0.89, 1.0, 0.86, 0.99, 0.85, 0.93, 0.98, 0.92, 1.0, 1.0, 0.98, 0.9, 0.94, 0.9, 0.92, 0.9, 0.94, 0.88, 0.9, 0.93, 0.96, 0.96, 0.93, 0.92, 0.9, 0.95, 0.99, 0.98, 1.0, 1.0, 1.0, 0.99, 0.97, 0.99, 0.92, 0.96, 0.96, 0.94, 0.97, 0.91, 0.88, 0.9, 0.91, 0.79, 0.9, 0.92, 0.92, 0.96, 0.9, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.84, 0.95, 0.78, 0.83, 0.87, 0.95, 0.72, 0.68, 0.64, 0.64, 0.73, 0.44, 0.31, 0.37, 0.06, 0.28, 0.03, 0.14, 0.42, 0.67, 0.11, 0.92, 0.41, 0.86, 0.58, 0.94, 0.52, 0.1, 0.04, 0.45, 0.02, 0.47, 0.69, 0.62, 0.18, 0.45, 0.0, 0.24, 0.04, 0.25, 0.23, 0.6, 0.32, 0.98, 0.72, 0.4, 0.29, 0.13, 0.35, 0.0, 0.24, 0.03, 0.56, 0.67, 0.58, 0.69, 0.64, 0.63, 0.1, 0.19, 0.0, 0.14, 0.11, 0.72, 0.36, 0.07, 0.14, 0.55, 0.36, 0.82, 0.86, 0.79, 0.67, 0.61, 0.76, 0.54, 1.0, 0.97, 0.92, 0.94, 0.89, 0.95, 0.96, 0.98, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.96, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.92, 0.98, 0.93, 0.98, 0.95, 1.0, 0.87, 1.0, 0.91, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.98, 1.0, 0.91, 1.0, 0.8, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.97, 1.0, 0.98, 0.99, 0.99, 1.0, 1.0, 0.99, 1.0, 0.92, 1.0, 0.86, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.91, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.99, 0.99, 1.0, 1.0, 0.98, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.93, 0.99, 0.85, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.97, 1.0, 0.99, 0.94, 0.99, 0.9, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.97, 0.96, 1.0, 0.79, 0.98, 0.75, 0.99, 0.62, 1.0, 0.83, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.95, 0.99, 0.96, 1.0, 0.99, 0.99, 0.94, 0.95, 0.95, 0.93, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.96, 1.0, 0.97, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.96, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.9, 1.0, 0.94, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.9, 0.82, 0.96, 0.83, 0.85, 0.95, 0.88, 0.93, 0.96, 0.96, 0.97, 0.99, 0.67, 0.43, 0.82, 0.83, 0.94, 0.95, 0.94, 0.88, 0.94, 0.79, 0.95, 0.81, 0.75, 0.73, 0.32, 0.3, 0.51, 0.05, 0.44, 0.01, 0.39, 0.5, 0.49, 0.11, 0.86, 0.44, 0.79, 0.46, 0.97, 0.51, 0.19, 0.02, 0.41, 0.02, 0.45, 0.68, 0.49, 0.12, 0.17, 0.0, 0.35, 0.04, 0.38, 0.71, 0.45, 0.61, 0.99, 0.53, 0.4, 0.31, 0.13, 0.48, 0.0, 0.14, 0.01, 0.58, 0.54, 0.51, 0.59, 0.63, 0.32, 0.05, 0.34, 0.0, 0.17, 0.14, 0.82, 0.27, 0.1, 0.62, 0.57, 0.38]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 57.094741
| 0.749189
| 671
|
O43255
|
Q86TG7
| null |
degron_data
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
PEG10
|
MTERRRDELSEEINNLREKVMKQSEENNNLQSQVQKLTEENTTLREQVEPTPEDEDDDIELRGAAAAAAPPPPIEEECPEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIRRLRQGMGSVIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELSHLEVAKSLSALIGQCIHIERRLARAAAARKPRSPPRALVLPHIASHHQVDPTEPVGGARMRLTQEEKERRRKLNLCLYCGTGGHYADNCPAKASKSSPAGKLPGPAVEGPSATGPEIIRSPQDDASSPHLQVMLQIHLPGRHTLFVRAMIDSGASGNFIDHEYVAQNGIPLRIKDWPILVEAIDGRPIASGPVVHETHDLIVDLGDHREVLSFDVTQSPFFPVVLGVRWLSTHDPNITWSTRSIVFDSEYCRYHCRMYSPIPPSLPPPAPQPPLYYPVDGYRVYQPVRYYYVQNVYTPVDEHVYPDHRLVDPHIEMIPGAHSIPSGHVYSLSEPEMAALRDFVARNVKDGLITPTIAPNGAQVLQVKRGWKLQVSYDCRAPNNFTIQNQYPRLSIPNLEDQAHLATYTEFVPQIPGYQTYPTYAAYPTYPVGFAWYPVGRDGQGRSLYVPVMITWNPHWYRQPPVPQYPPPQPPPPPPPPPPPPSYSTL
|
Homo sapiens
|
Extracellular vesicle membrane, Cytoplasm, Nucleus
|
Tissue enhanced (adrenal gland, placenta)
|
{'Ciliated cells': '15.6', 'Basal respiratory cells': '2.2', 'Club cells': '61.3', 'Ionocytes': '0.4', 'Mucus glandular cells': '23.3', 'Serous glandular cells': '15.6', 'Gastric mucus-secreting cells': '0.6', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.3', 'Intestinal goblet cells': '0.6', 'Exocrine glandular cells': '-0.106', 'Basal prostatic cells': '26.1', 'Prostatic glandular cells': '6.1', 'Breast glandular cells': '0.492', 'Breast myoepithelial cells': '0.664', 'Glandular and luminal cells': '15.2', 'Secretory cells': '44.3', 'Basal keratinocytes': '7.2', 'Suprabasal keratinocytes': '2.0', 'Basal squamous epithelial cells': '3.1', 'Squamous epithelial cells': '1.6', 'Alveolar cells type 1': '0.230', 'Alveolar cells type 2': '0.515', 'Salivary duct cells': '36.1', 'Ductal cells': '0.243', 'Hepatocytes': '0.403', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.217', 'Distal tubular cells': '86.1', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.571', 'Sertoli cells': '0.780', 'Granulosa cells': '73.0', 'Enteroendocrine cells': '15.6', 'Pancreatic endocrine cells': '39.1', 'Leydig cells': '0.480', 'Excitatory neurons': '15.3', 'Inhibitory neurons': '20.9', 'Cone photoreceptor cells': '11.9', 'Rod photoreceptor cells': '24.6', 'Bipolar cells': '68.6', 'Horizontal cells': '37.8', 'Astrocytes': '10.8', 'Oligodendrocyte precursor cells': '9.4', 'Oligodendrocytes': '11.9', 'Microglial cells': '4.5', 'Muller glia cells': '84.6', 'Schwann cells': '0.033', 'Spermatogonia': '0.551', 'Spermatocytes': '0.371', 'Early spermatids': '-0.308', 'Late spermatids': '-0.523', 'Oocytes': '12.5', 'Cytotrophoblasts': '1967.3', 'Syncytiotrophoblasts': '2322.6', 'Extravillous trophoblasts': '68.6', 'Endothelial cells': '5.1', 'Lymphatic endothelial cells': '28.5', 'Cardiomyocytes': '0.473', 'Skeletal myocytes': '0.320', 'Smooth muscle cells': '24.7', 'Adipocytes': '4.6', 'Melanocytes': '0.003', 'Fibroblasts': '23.5', 'Peritubular cells': '0.345', 'Endometrial stromal cells': '2.7', 'Ovarian stromal cells': '117.9', 'Undifferentiated cells': '1.2', 'T-cells': '2.7', 'B-cells': '27.6', 'Plasma cells': '3.2', 'Nk-cells': '2.0', 'Granulocytes': '8.7', 'Monocytes': '0.2', 'Macrophages': '1.5', 'Hofbauer cells': '50.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.4', 'Langerhans cells': '-0.051', 'Erythroid cells': '0.012', 'Adipocytes (Subcutaneous)': '-0.292', 'Adipocytes (Visceral)': '-0.329', 'Breast glandular cells (progenitors)': '0.552', 'Adipocytes (Breast)': '-0.452', 'Colon enterocytes': '-0.179', 'Colon enteroendocrine cells': '0.286', 'Enteric glia cells': '0.066', 'Mitotic cells (Colon)': '-0.292', 'Mitotic cells (Heart)': '0.426', 'Podocytes': '-0.037', 'Ascending Loop of Henle cells': '0.600', 'Intercalated cells': '0.139', 'Cholangiocyte': '0.007', 'NK-cells (Liver)': '0.321', 'Respiratory ciliated cells': '-0.086', 'Mitotic cells (Lung)': '0.132', 'NK-cells (Lung)': '-0.244', 'B-cells (Lung)': '-0.265', 'Alpha cells': '0.470', 'Beta cells': '0.405', 'Prostate glandular cells': '0.099', 'Prostate basal glandular cells': '-0.205', 'Urothelial cells': '-0.411', 'Keratinocyte (other)': '-0.296', 'Keratinocyte (granular)': '-0.315', 'Hair cortex cells': '0.276', 'Inner root sheath cells': '0.344', 'Outer root sheath cells': '0.451', 'Sebaceous gland cells': '0.179', 'Eccrine sweat gland cells': '0.684', 'Adipocytes (Skin)': '0.394', 'Mitotic cells (Skin)': '0.268', 'Parietal cells': '-0.658', 'Chief cells': '-0.504', 'Gastric mucous cells': '-0.690', 'Gastric enteroendocrine cells': '-0.411', 'Mitotic cells (Stomach)': '-0.300', 'Parafollicular cells': '0.149', 'Thyroid glandular cells': '0.578', 'Mitotic cells (Thyroid)': '0.110', 'Adrenal cortex cells': '0.465', 'Adrenal medulla cells': '-0.098', 'Mitotic cells (Adrenal gland)': '0.229', 'Minor salivary glandular cells': '0.425', 'Minor salivary gland ductal cells': '0.467', 'Minor salivary gland basal cells': '-0.031', 'Mitotic cells (Minor salivary gland)': '0.085', 'Adipocytes (Minor salivary gland)': '0.041', 'Somatotropes': '0.104', 'Lactotropes': '0.501', 'Gonadotropes': '0.513', 'Corticotropes': '0.191', 'Thyrotropes': '0.499', 'Undifferentiated cells (Pituitary gland)': '0.005', 'Mitotic cells (Spleen)': '0.223', 'Platelets': '-0.104', 'Erythrocytes': '0.010', 'Hematopoietic stem cells': '-0.136', 'B-cells (Spleen)': '0.197', 'NK-cells (Spleen)': '0.128', 'Amygdala excitatory': '89.7', 'Cerebellar inhibitory': '28.6', 'Cge interneuron': '94.2', 'Deep-layer corticothalamic and 6b': '29.4', 'Deep-layer intratelencephalic': '31.1', 'Deep-layer near-projecting': '54.1', 'Eccentric medium spiny neuron': '216.7', 'Hippocampal ca1-3': '45.5', 'Hippocampal ca4': '23.8', 'Hippocampal dentate gyrus': '75.1', 'Lamp5-lhx6 and chandelier': '63.8', 'Lower rhombic lip': '68.6', 'Mammillary body': '24.9', 'Medium spiny neuron': '174.8', 'Mge interneuron': '45.0', 'Midbrain-derived inhibitory': '54.1', 'Miscellaneous': '60.3', 'Splatter': '197.0', 'Thalamic excitatory': '36.4', 'Upper rhombic lip': '102.0', 'Upper-layer intratelencephalic': '33.4', 'Astrocyte': '11.7', 'Bergmann glia': '11.7', 'Central nervous system macrophage': '8.4', 'Choroid plexus epithelial cell': '12.2', 'Committed oligodendrocyte precursor': '20.9', 'Ependymal cell': '23.4', 'Oligodendrocyte': '25.6', 'Oligodendrocyte precursor cell': '25.4', 'Endothelial cell': '7.3', 'Pericyte': '7.5', 'Vascular associated smooth muscle cell': '23.2', 'Fibroblast': '7.5', 'Leukocyte': '8.9', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.3', 'GdT-cell': '0.1', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.5', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '0.5', 'Naive B-cell': '38.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.8', 'Total PBMC': '0.7', 'Vd2 gdTCR': '0.4', 'Memory CD4 T-cell Th1\\/Th17': '0.6', 'Memory CD4 T-cell Th17': '0.7', 'Memory CD4 T-cell Th2': '0.9', 'Non-Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1': '0.9', 'Memory CD4 T-cell TFH': '0.9', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.8', 'Effector memory CD8 T-cell': '1.0', 'Terminal effector memory CD8 T-cell': '1.5', 'Non-switched memory B-cell': '6.9', 'Plasmablast': '0.5', 'Switched memory B-cell': '2.8', 'Exhausted memory B-cell': '8.1', 'Progenitor cell': '0.0', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '1.5', 'Naive CD8 T-cell activated': '1.1', 'Naive T-reg': '0.7'}
|
7LGA
|
{'Adipose Tissue': 3.9126409468438537, 'Adrenal Gland': 289.66015503875974, 'Bladder': 9.312285714285714, 'Blood': 4.086597289558665, 'Blood Vessel': 5.415154307116104, 'Brain': 85.44175548826647, 'Breast': 7.741166448801743, 'Cervix Uteri': 9.842410526315788, 'Colon': 9.779884813863928, 'Esophagus': 2.568608249134948, 'Fallopian Tube': 9.279111111111112, 'Heart': 0.8877085365853659, 'Kidney': 3.5912775280898876, 'Liver': 0.994191592920354, 'Lung': 22.624176297577858, 'Muscle': 1.404791207970112, 'Nerve': 17.44798222940226, 'Ovary': 61.95797222222222, 'Pancreas': 3.167163109756098, 'Pituitary': 253.37642402826856, 'Prostate': 2.464942448979592, 'Salivary Gland': 5.534122222222222, 'Skin': 8.49217841901603, 'Small Intestine': 3.93478128342246, 'Spleen': 1.407013278008299, 'Stomach': 6.164984401114206, 'Testis': 49.6509972299169, 'Thyroid': 4.3972042879019915, 'Uterus': 7.333242253521127, 'Vagina': 4.789858333333333}
|
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|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[55.01, 78.66, 76.45, 78.0, 81.3, 86.6, 85.93, 84.18, 85.97, 88.29, 88.68, 86.86, 92.69, 91.64, 91.65, 91.55, 93.59, 92.39, 93.48, 94.37, 93.29, 92.67, 91.28, 93.25, 92.53, 92.38, 90.75, 92.38, 93.84, 90.87, 93.05, 92.91, 94.13, 92.85, 91.98, 93.24, 89.87, 90.98, 89.33, 89.15, 77.52, 83.09, 83.04, 74.65, 70.8, 73.88, 71.47, 63.29, 47.7, 48.52, 39.28, 40.01, 39.85, 33.78, 34.69, 29.71, 34.53, 28.28, 34.27, 27.37, 26.38, 29.79, 25.82, 25.57, 25.32, 26.89, 26.04, 27.38, 27.43, 30.85, 33.11, 35.11, 33.44, 37.0, 37.78, 39.46, 33.66, 37.78, 48.33, 53.95, 67.37, 78.56, 83.33, 88.64, 91.5, 95.2, 92.32, 89.74, 89.9, 86.3, 85.24, 90.19, 89.57, 87.59, 90.56, 94.36, 92.08, 90.01, 92.06, 90.96, 89.4, 89.73, 87.75, 86.24, 82.18, 79.48, 75.2, 66.33, 59.93, 69.87, 75.98, 75.41, 77.49, 82.91, 82.84, 82.17, 86.66, 87.66, 85.7, 90.66, 92.81, 89.01, 88.37, 92.23, 93.91, 93.26, 92.46, 92.4, 94.48, 93.17, 92.54, 94.95, 92.75, 89.07, 90.6, 90.4, 87.98, 85.18, 83.81, 84.84, 79.58, 85.93, 85.65, 81.66, 82.55, 82.87, 89.24, 91.65, 89.94, 93.08, 93.65, 89.78, 90.07, 91.92, 89.45, 86.57, 88.79, 91.46, 85.26, 80.57, 76.3, 81.74, 82.08, 82.13, 83.88, 87.51, 90.63, 90.96, 91.1, 94.61, 96.47, 93.45, 94.15, 95.83, 94.33, 94.67, 87.43, 81.11, 84.05, 91.2, 93.76, 92.75, 92.3, 96.68, 96.46, 92.98, 93.9, 97.59, 94.99, 91.84, 93.21, 93.64, 88.7, 85.49, 88.53, 83.84, 90.0, 91.43, 90.47, 93.13, 93.84, 95.57, 94.68, 93.63, 96.43, 96.79, 93.83, 93.31, 93.97, 95.57, 92.9, 89.08, 89.02, 91.49, 91.07, 90.27, 88.92, 89.66, 88.0, 87.79, 86.61, 86.06, 85.33, 87.39, 87.7, 92.08, 92.34, 93.14, 93.28, 94.39, 94.96, 93.48, 93.89, 94.71, 94.28, 93.19, 93.37, 93.68, 92.24, 92.41, 88.67, 87.85, 86.62, 85.68, 82.87, 78.32, 76.83, 73.05, 60.97, 58.21, 50.81, 46.32, 51.64, 42.78, 38.65, 42.26, 39.21, 30.15, 33.94, 28.78, 30.98, 30.09, 27.89, 33.18, 27.75, 29.93, 24.44, 29.73, 27.89, 27.87, 30.27, 27.77, 31.71, 31.42, 32.07, 33.67, 36.04, 38.4, 39.54, 55.5, 66.66, 77.69, 74.91, 72.55, 78.44, 77.5, 78.65, 86.5, 83.12, 80.86, 79.45, 81.01, 78.27, 82.24, 81.29, 80.04, 72.25, 78.38, 71.84, 69.86, 70.8, 74.25, 80.59, 74.56, 68.28, 65.47, 64.33, 71.06, 63.34, 60.14, 52.67, 35.04, 30.0, 28.89, 25.78, 23.86, 29.62, 23.77, 22.76, 25.31, 23.19, 27.67, 23.3, 27.88, 22.33, 27.09, 22.67, 26.7, 32.55, 28.16, 33.46, 40.63, 40.96, 50.34, 59.93, 62.34, 65.43, 58.95, 57.47, 57.47, 50.42, 50.32, 50.09, 49.47, 56.19, 66.23, 72.96, 82.21, 86.32, 87.87, 88.37, 88.39, 92.14, 89.26, 91.59, 83.96, 80.89, 66.12, 66.84, 72.07, 76.48, 85.02, 90.83, 88.64, 90.71, 87.88, 92.2, 92.39, 91.6, 89.69, 88.62, 85.23, 86.98, 81.75, 88.09, 93.72, 94.03, 94.03, 93.74, 88.33, 88.9, 90.82, 91.17, 88.76, 88.43, 88.47, 85.61, 88.45, 87.77, 87.03, 80.09, 76.11, 64.99, 63.54, 56.94, 63.39, 68.08, 70.54, 71.93, 73.6, 78.57, 72.29, 74.37, 66.39, 71.81, 66.9, 70.22, 65.8, 68.22, 71.2, 71.75, 75.93, 80.59, 82.49, 87.77, 89.43, 87.41, 86.96, 88.21, 87.61, 90.72, 85.98, 86.12, 78.99, 73.16, 78.92, 84.83, 85.45, 87.65, 90.72, 91.32, 94.12, 92.28, 88.93, 88.0, 83.1, 81.14, 68.43, 78.68, 86.78, 90.68, 95.14, 94.25, 94.32, 92.2, 89.32, 85.07, 90.86, 90.77, 86.22, 86.32, 85.84, 85.84, 87.37, 82.31, 84.9, 80.87, 80.24, 76.25, 77.96, 71.88, 76.16, 82.6, 81.24, 78.09, 73.07, 79.53, 76.21, 79.51, 79.88, 74.63, 73.0, 72.95, 77.01, 66.88, 52.56, 46.22, 38.35, 39.28, 41.83, 39.11, 38.68, 40.61, 40.95, 42.24, 42.85, 38.08, 45.84, 42.58, 43.95, 46.18, 45.58, 47.32, 53.95, 51.48, 49.85, 47.84, 53.01, 43.4, 39.13, 46.93, 45.37, 45.79, 44.77, 39.96, 34.11, 33.35, 31.58, 31.04, 32.04, 32.54, 34.98, 33.64, 38.76, 37.15, 38.97, 39.41, 49.24, 54.64, 58.62, 64.87, 64.54, 66.02, 61.33, 55.77, 57.17, 46.26, 39.71, 44.65, 56.51, 56.55, 64.2, 68.78, 70.75, 73.52, 78.99, 70.8, 68.28, 68.1, 60.5, 62.02, 62.36, 61.58, 62.38, 61.41, 66.6, 66.84, 72.47, 78.03, 83.53, 88.42, 89.65, 88.68, 89.37, 87.53, 89.68, 88.83, 89.57, 89.61, 90.86, 88.58, 88.89, 89.43, 87.38, 86.27, 87.23, 84.58, 81.52, 78.56, 79.41, 83.33, 78.07, 75.72, 69.76, 62.53, 64.35, 62.07, 64.73, 61.43, 64.78, 70.73, 73.03, 82.01, 81.89, 84.75, 83.08, 80.35, 74.51, 75.47, 81.68, 85.48, 84.11, 85.64, 82.19, 80.48, 76.28, 74.31, 75.22, 73.47, 72.31, 75.05, 77.68, 75.12, 74.63, 73.32, 68.0, 63.21, 49.98, 47.32, 39.87, 41.59, 36.57, 37.12, 35.94, 32.09, 34.98, 35.6, 36.1, 33.46, 32.05, 29.03, 30.75, 35.3, 34.01, 32.44, 33.13, 31.91, 33.11, 35.81, 37.89, 40.79, 42.82, 34.7, 37.03, 40.16, 27.14, 33.3, 35.5, 29.65, 33.43, 33.4, 28.95, 29.41, 31.82, 28.16, 30.14, 36.35, 33.71, 33.16, 34.39, 35.7, 37.92, 39.86, 40.7, 38.57, 39.89, 40.33, 37.11, 41.51, 43.42, 35.71, 45.62, 38.59, 43.3, 42.75, 35.76, 41.38, 40.85, 37.19, 38.9, 39.69, 40.21, 38.73, 33.54, 37.13, 37.22, 36.02, 34.68, 31.08, 33.76, 33.7, 34.79, 30.16, 32.23, 31.28, 30.05, 32.2, 38.03, 40.02, 40.47, 43.17, 47.05, 53.54, 57.64, 61.02, 64.65, 66.12, 66.4, 66.02, 65.31, 63.04, 64.43, 59.04, 52.67, 50.03, 47.35, 47.73, 37.64]
|
[0.79, 0.73, 0.78, 0.76, 0.6, 0.7, 0.63, 0.56, 0.4, 0.45, 0.71, 0.6, 0.5, 0.54, 0.51, 0.56, 0.63, 0.62, 0.62, 0.63, 0.59, 0.6, 0.6, 0.45, 0.68, 0.52, 0.51, 0.57, 0.69, 0.56, 0.65, 0.55, 0.6, 0.6, 0.63, 0.6, 0.5, 0.56, 0.58, 0.46, 0.53, 0.51, 0.49, 0.54, 0.76, 0.77, 0.71, 0.77, 0.82, 0.88, 0.9, 0.83, 0.94, 0.9, 0.97, 0.99, 0.85, 0.97, 0.87, 0.93, 0.97, 0.96, 1.0, 0.99, 0.99, 0.88, 0.96, 0.88, 0.87, 0.96, 0.94, 0.89, 0.89, 0.87, 0.91, 0.82, 0.92, 0.77, 0.77, 0.88, 0.57, 0.58, 0.11, 0.62, 0.66, 0.01, 0.51, 0.07, 0.39, 0.36, 0.69, 0.44, 0.06, 0.6, 0.4, 0.04, 0.24, 0.42, 0.33, 0.0, 0.51, 0.54, 0.21, 0.1, 0.59, 0.61, 0.32, 0.58, 0.93, 0.74, 0.09, 0.65, 0.59, 0.22, 0.48, 0.39, 0.27, 0.01, 0.4, 0.13, 0.0, 0.21, 0.6, 0.04, 0.06, 0.33, 0.52, 0.61, 0.0, 0.23, 0.67, 0.18, 0.0, 0.48, 0.37, 0.24, 0.09, 0.68, 0.87, 0.21, 0.62, 0.67, 0.0, 0.3, 0.6, 0.39, 0.18, 0.64, 0.17, 0.0, 0.09, 0.7, 0.26, 0.0, 0.44, 0.79, 0.57, 0.07, 0.5, 0.38, 0.75, 0.68, 0.39, 0.42, 0.48, 0.31, 0.03, 0.3, 0.49, 0.56, 0.01, 0.62, 0.76, 0.2, 0.51, 0.09, 0.65, 1.0, 0.44, 0.31, 0.0, 0.46, 0.58, 0.03, 0.04, 0.48, 0.28, 0.0, 0.45, 0.68, 0.17, 0.16, 0.8, 0.34, 0.14, 0.66, 0.24, 0.66, 0.44, 0.57, 0.3, 0.12, 0.13, 0.67, 0.1, 0.0, 0.38, 0.53, 0.02, 0.05, 0.13, 0.73, 0.56, 0.0, 0.23, 0.64, 0.32, 0.08, 0.73, 0.74, 0.47, 0.89, 0.87, 0.13, 0.87, 0.26, 0.1, 0.66, 0.43, 0.05, 0.1, 0.46, 0.26, 0.0, 0.22, 0.64, 0.02, 0.27, 0.6, 0.47, 0.37, 0.52, 0.73, 0.48, 0.52, 0.55, 0.76, 0.85, 0.77, 0.87, 0.92, 0.89, 0.88, 0.88, 0.94, 0.81, 0.91, 0.9, 0.93, 0.87, 0.98, 0.97, 0.96, 0.88, 0.86, 0.87, 0.87, 0.9, 0.92, 0.97, 0.89, 0.92, 0.92, 0.91, 0.79, 0.97, 0.79, 0.93, 0.82, 0.93, 0.22, 0.61, 0.57, 0.76, 0.25, 0.41, 0.51, 0.52, 0.17, 0.55, 0.86, 0.57, 0.63, 0.27, 0.01, 0.42, 0.57, 0.45, 0.3, 0.5, 0.6, 0.93, 0.23, 0.77, 0.2, 0.86, 0.76, 0.05, 0.7, 0.58, 0.5, 0.86, 0.9, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.97, 0.96, 0.79, 0.36, 0.48, 0.57, 0.11, 0.63, 0.16, 0.33, 0.82, 0.93, 0.41, 0.78, 0.81, 0.2, 0.86, 0.46, 0.09, 0.12, 0.01, 0.42, 0.02, 0.36, 0.0, 0.14, 0.09, 0.81, 0.85, 0.64, 0.74, 0.39, 0.08, 0.59, 0.04, 0.32, 0.0, 0.12, 0.12, 0.34, 0.65, 0.77, 0.13, 0.52, 0.09, 0.14, 0.09, 0.0, 0.11, 0.52, 0.58, 0.17, 0.03, 0.6, 0.71, 0.27, 0.41, 0.06, 0.46, 0.33, 0.47, 0.78, 0.2, 0.94, 0.87, 0.31, 0.35, 0.59, 0.16, 0.62, 0.45, 0.99, 0.64, 0.47, 0.71, 0.68, 0.26, 0.92, 0.34, 0.34, 0.44, 0.0, 0.41, 0.37, 0.11, 0.0, 0.49, 0.68, 0.01, 0.34, 0.03, 0.11, 0.04, 0.59, 0.22, 0.03, 0.28, 0.17, 0.65, 0.12, 0.32, 0.0, 0.14, 0.09, 0.11, 0.66, 0.2, 0.8, 0.96, 0.21, 0.23, 0.0, 0.1, 0.01, 0.0, 0.37, 0.68, 0.04, 0.14, 0.66, 0.47, 0.01, 0.71, 0.17, 0.49, 0.21, 0.46, 0.66, 0.9, 0.48, 0.3, 0.05, 0.02, 0.16, 0.03, 0.54, 0.17, 0.63, 0.44, 0.01, 0.72, 0.78, 0.66, 0.02, 0.33, 0.67, 0.81, 0.6, 0.82, 0.57, 0.79, 0.85, 0.8, 0.87, 0.88, 0.95, 0.76, 0.87, 0.9, 0.82, 0.88, 0.58, 0.65, 0.34, 0.59, 0.57, 0.46, 0.87, 0.25, 0.39, 0.36, 0.05, 0.3, 0.69, 0.8, 0.76, 0.92, 0.66, 0.87, 0.77, 0.66, 0.78, 0.73, 0.75, 0.81, 0.31, 0.85, 0.65, 0.57, 0.83, 0.56, 0.62, 0.65, 0.73, 0.88, 0.84, 0.71, 0.71, 0.86, 0.49, 0.82, 0.73, 0.78, 0.33, 0.51, 0.46, 0.88, 0.61, 0.26, 0.82, 0.61, 0.32, 0.39, 0.75, 0.46, 0.88, 0.87, 0.32, 0.95, 0.23, 0.35, 0.83, 0.54, 0.11, 0.39, 0.37, 0.23, 0.19, 0.61, 0.57, 0.16, 0.34, 0.57, 0.62, 0.12, 0.42, 0.9, 0.42, 0.45, 0.16, 0.25, 0.87, 0.83, 0.78, 0.96, 0.5, 0.91, 0.25, 0.67, 0.29, 0.32, 0.24, 0.2, 0.28, 0.12, 0.57, 0.69, 0.77, 0.96, 0.64, 0.39, 0.48, 0.2, 0.28, 0.56, 0.17, 0.43, 0.69, 0.45, 0.22, 0.39, 0.7, 0.33, 0.14, 0.39, 0.71, 0.29, 0.87, 0.67, 0.55, 0.94, 0.64, 0.8, 0.74, 0.55, 0.61, 0.82, 0.84, 0.59, 0.68, 0.59, 0.44, 0.71, 0.42, 0.1, 0.46, 0.02, 0.39, 0.59, 0.38, 0.66, 0.79, 0.8, 0.93, 0.95, 0.89, 0.87, 0.89, 0.88, 0.89, 0.67, 0.93, 0.83, 0.88, 0.86, 0.97, 0.89, 0.66, 0.93, 0.48, 0.41, 0.62, 0.38, 0.55, 0.54, 0.37, 0.59, 0.45, 0.49, 0.28, 0.99, 0.77, 0.49, 0.61, 0.41, 0.44, 0.43, 0.21, 0.08, 0.17, 0.1, 0.27, 0.49, 0.5, 0.64, 0.39, 0.82, 0.86, 0.82, 0.92, 0.94, 0.76, 0.9, 0.85, 0.64, 0.91, 0.69, 0.93, 0.9, 0.93, 0.94, 0.92, 0.93, 0.95, 0.95, 0.95, 0.93, 0.96, 0.93, 0.93, 0.95, 0.92, 0.84, 0.8, 0.95, 0.81, 1.0, 1.0]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 67.732669
| 0.545268
| 1,010
|
O43255
|
Q86TG7-2
| null |
degron_data
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
PEG10
|
MTERRRDELSEEINNLREKVMKQSEENNNLQSQVQKLTEENTTLREQVEPTPEDEDDDIELRGAAAAAAPPPPIEEECPEDLPEKFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCFVTSMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIRRLRQGMGSVIDYSNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELSHLEVAKSLSALIGQCIHIERRLARAAAARKPRSPPRALVLPHIASHHQVDPTEPVGGARMRLTQEEKERRRKLNLCLYCGTGGHYADNCPAKASKSSPAGNSPAPL
|
Homo sapiens
| null |
Not found
|
{}
| null |
{'Adipose Tissue': 3.9126409468438537, 'Adrenal Gland': 289.66015503875974, 'Bladder': 9.312285714285714, 'Blood': 4.086597289558665, 'Blood Vessel': 5.415154307116104, 'Brain': 85.44175548826647, 'Breast': 7.741166448801743, 'Cervix Uteri': 9.842410526315788, 'Colon': 9.779884813863928, 'Esophagus': 2.568608249134948, 'Fallopian Tube': 9.279111111111112, 'Heart': 0.8877085365853659, 'Kidney': 3.5912775280898876, 'Liver': 0.994191592920354, 'Lung': 22.624176297577858, 'Muscle': 1.404791207970112, 'Nerve': 17.44798222940226, 'Ovary': 61.95797222222222, 'Pancreas': 3.167163109756098, 'Pituitary': 253.37642402826856, 'Prostate': 2.464942448979592, 'Salivary Gland': 5.534122222222222, 'Skin': 8.49217841901603, 'Small Intestine': 3.93478128342246, 'Spleen': 1.407013278008299, 'Stomach': 6.164984401114206, 'Testis': 49.6509972299169, 'Thyroid': 4.3972042879019915, 'Uterus': 7.333242253521127, 'Vagina': 4.789858333333333}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
| null | null |
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| null | null | 1,010
|
O43255
|
Q92630
|
22199232, UNIPROT
|
UbiNet, UbiBrowser, 31181401
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
DYRK2
|
MLTRKPSAAAPAAYPTGRGGDSAVRQLQASPGLGAGATRSGVGTGPPSPIALPPLRASNAAAAAHTIGGSKHTMNDHLHVGSHAHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTGLPVVPERQLDSIHRRQGSSTSLKSMEGMGKVKATPMTPEQAMKQYMQKLTAFEHHEIFSYPEIYFLGLNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTGEKTSVKRITESTGAITSISKLPPPSSSASKLRTNLAQMTDANGNIQQRTVLPKLVS
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '31.3', 'Basal respiratory cells': '6.6', 'Club cells': '15.6', 'Ionocytes': '11.8', 'Mucus glandular cells': '13.0', 'Serous glandular cells': '11.7', 'Gastric mucus-secreting cells': '25.4', 'Proximal enterocytes': '54.3', 'Paneth cells': '31.1', 'Distal enterocytes': '78.4', 'Intestinal goblet cells': '70.5', 'Exocrine glandular cells': '-0.602', 'Basal prostatic cells': '12.3', 'Prostatic glandular cells': '7.1', 'Breast glandular cells': '0.373', 'Breast myoepithelial cells': '0.504', 'Glandular and luminal cells': '13.8', 'Secretory cells': '17.2', 'Basal keratinocytes': '11.7', 'Suprabasal keratinocytes': '13.6', 'Basal squamous epithelial cells': '11.3', 'Squamous epithelial cells': '15.5', 'Alveolar cells type 1': '0.099', 'Alveolar cells type 2': '-0.544', 'Salivary duct cells': '13.9', 'Ductal cells': '0.688', 'Hepatocytes': '0.190', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.291', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.366', 'Sertoli cells': '0.585', 'Granulosa cells': '7.1', 'Enteroendocrine cells': '23.1', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.644', 'Excitatory neurons': '10.6', 'Inhibitory neurons': '10.9', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '25.4', 'Bipolar cells': '18.1', 'Horizontal cells': '30.2', 'Astrocytes': '3.7', 'Oligodendrocyte precursor cells': '5.7', 'Oligodendrocytes': '8.4', 'Microglial cells': '12.5', 'Muller glia cells': '14.7', 'Schwann cells': '0.167', 'Spermatogonia': '0.658', 'Spermatocytes': '0.206', 'Early spermatids': '-0.429', 'Late spermatids': '-0.675', 'Oocytes': '2.2', 'Cytotrophoblasts': '3.4', 'Syncytiotrophoblasts': '4.4', 'Extravillous trophoblasts': '8.6', 'Endothelial cells': '9.6', 'Lymphatic endothelial cells': '8.8', 'Cardiomyocytes': '0.603', 'Skeletal myocytes': '0.615', 'Smooth muscle cells': '19.7', 'Adipocytes': '11.9', 'Melanocytes': '0.284', 'Fibroblasts': '17.9', 'Peritubular cells': '0.575', 'Endometrial stromal cells': '34.0', 'Ovarian stromal cells': '8.1', 'Undifferentiated cells': '23.0', 'T-cells': '35.8', 'B-cells': '18.7', 'Plasma cells': '4.2', 'Nk-cells': '42.8', 'Granulocytes': '14.7', 'Monocytes': '15.8', 'Macrophages': '16.7', 'Hofbauer cells': '15.2', 'Kupffer cells': '11.1', 'Dendritic cells': '4.6', 'Langerhans cells': '0.220', 'Erythroid cells': '0.049', 'Adipocytes (Subcutaneous)': '-0.539', 'Adipocytes (Visceral)': '-0.485', 'Breast glandular cells (progenitors)': '0.190', 'Adipocytes (Breast)': '-0.535', 'Colon enterocytes': '0.052', 'Colon enteroendocrine cells': '0.102', 'Enteric glia cells': '0.274', 'Mitotic cells (Colon)': '0.066', 'Mitotic cells (Heart)': '0.529', 'Podocytes': '-0.130', 'Ascending Loop of Henle cells': '0.315', 'Intercalated cells': '-0.163', 'Cholangiocyte': '0.339', 'NK-cells (Liver)': '-0.113', 'Respiratory ciliated cells': '0.192', 'Mitotic cells (Lung)': '-0.082', 'NK-cells (Lung)': '0.480', 'B-cells (Lung)': '0.372', 'Alpha cells': '0.466', 'Beta cells': '0.270', 'Prostate glandular cells': '-0.526', 'Prostate basal glandular cells': '-0.029', 'Urothelial cells': '0.280', 'Keratinocyte (other)': '0.054', 'Keratinocyte (granular)': '-0.272', 'Hair cortex cells': '0.261', 'Inner root sheath cells': '0.329', 'Outer root sheath cells': '0.493', 'Sebaceous gland cells': '0.127', 'Eccrine sweat gland cells': '0.090', 'Adipocytes (Skin)': '-0.004', 'Mitotic cells (Skin)': '0.492', 'Parietal cells': '-0.314', 'Chief cells': '-0.402', 'Gastric mucous cells': '0.108', 'Gastric enteroendocrine cells': '-0.147', 'Mitotic cells (Stomach)': '0.297', 'Parafollicular cells': '-0.023', 'Thyroid glandular cells': '0.076', 'Mitotic cells (Thyroid)': '0.315', 'Adrenal cortex cells': '0.269', 'Adrenal medulla cells': '0.001', 'Mitotic cells (Adrenal gland)': '0.213', 'Minor salivary glandular cells': '0.274', 'Minor salivary gland ductal cells': '-0.201', 'Minor salivary gland basal cells': '0.528', 'Mitotic cells (Minor salivary gland)': '0.699', 'Adipocytes (Minor salivary gland)': '0.189', 'Somatotropes': '-0.087', 'Lactotropes': '0.151', 'Gonadotropes': '0.083', 'Corticotropes': '-0.002', 'Thyrotropes': '0.334', 'Undifferentiated cells (Pituitary gland)': '0.130', 'Mitotic cells (Spleen)': '-0.159', 'Platelets': '-0.128', 'Erythrocytes': '-0.181', 'Hematopoietic stem cells': '-0.265', 'B-cells (Spleen)': '0.536', 'NK-cells (Spleen)': '0.395', 'Amygdala excitatory': '19.8', 'Cerebellar inhibitory': '20.8', 'Cge interneuron': '19.9', 'Deep-layer corticothalamic and 6b': '25.9', 'Deep-layer intratelencephalic': '22.5', 'Deep-layer near-projecting': '41.6', 'Eccentric medium spiny neuron': '12.6', 'Hippocampal ca1-3': '40.0', 'Hippocampal ca4': '36.7', 'Hippocampal dentate gyrus': '7.8', 'Lamp5-lhx6 and chandelier': '17.7', 'Lower rhombic lip': '19.6', 'Mammillary body': '7.9', 'Medium spiny neuron': '14.1', 'Mge interneuron': '15.9', 'Midbrain-derived inhibitory': '10.9', 'Miscellaneous': '16.8', 'Splatter': '10.8', 'Thalamic excitatory': '10.5', 'Upper rhombic lip': '9.3', 'Upper-layer intratelencephalic': '15.3', 'Astrocyte': '6.8', 'Bergmann glia': '7.4', 'Central nervous system macrophage': '39.0', 'Choroid plexus epithelial cell': '15.0', 'Committed oligodendrocyte precursor': '9.4', 'Ependymal cell': '44.7', 'Oligodendrocyte': '13.6', 'Oligodendrocyte precursor cell': '14.2', 'Endothelial cell': '10.7', 'Pericyte': '72.0', 'Vascular associated smooth muscle cell': '33.7', 'Fibroblast': '14.3', 'Leukocyte': '73.1', 'Basophil': '7.9', 'Eosinophil': '4.0', 'Neutrophil': '1.0', 'Classical monocyte': '10.1', 'Non-classical monocyte': '41.3', 'Intermediate monocyte': '6.1', 'T-reg': '29.6', 'GdT-cell': '3.2', 'MAIT T-cell': '29.5', 'Memory CD4 T-cell': '2.3', 'Naive CD4 T-cell': '154.7', 'Memory CD8 T-cell': '4.2', 'Naive CD8 T-cell': '149.3', 'Memory B-cell': '1.8', 'Naive B-cell': '58.2', 'Plasmacytoid DC': '4.2', 'Myeloid DC': '11.6', 'NK-cell': '93.2', 'Total PBMC': '15.4', 'Vd2 gdTCR': '24.0', 'Memory CD4 T-cell TFH': '105.4', 'Memory CD4 T-cell Th2': '114.6', 'Memory CD4 T-cell Th17': '95.5', 'Memory CD4 T-cell Th1\\/Th17': '108.2', 'Non-Vd2 gdTCR': '27.1', 'Memory CD4 T-cell Th1': '100.1', 'Terminal effector memory CD4 T-cell': '34.6', 'Central memory CD8 T-cell': '30.8', 'Effector memory CD8 T-cell': '25.6', 'Terminal effector memory CD8 T-cell': '25.2', 'Switched memory B-cell': '18.6', 'Plasmablast': '2.0', 'Non-switched memory B-cell': '9.1', 'Exhausted memory B-cell': '17.7', 'Progenitor cell': '9.1', 'Naive CD4 T-cell activated': '39.8', 'Naive CD8 T-cell activated': '38.5', 'Memory T-reg': '88.8', 'Naive T-reg': '184.6'}
|
3K2L, 3KVW, 4AZF, 5LXC, 5LXD, 5ZTN, 6HDP, 6HDR, 6K0J, 7AKF, 7AKH, 7DG4, 7DH3, 7DH9, 7DHC, 7DHH, 7DHK, 7DHN, 7DHO, 7DHV, 7DJO, 7DL6, 8HLT
|
{'Adipose Tissue': 8.982455980066446, 'Adrenal Gland': 3.811801162790698, 'Bladder': 10.147095238095238, 'Blood': 4.456802820236813, 'Blood Vessel': 12.44750786516854, 'Brain': 2.332287395912188, 'Breast': 6.766930283224402, 'Cervix Uteri': 9.990263157894736, 'Colon': 13.603590500641848, 'Esophagus': 8.799671280276817, 'Fallopian Tube': 10.990111111111112, 'Heart': 8.858548199767712, 'Kidney': 3.81938202247191, 'Liver': 1.8486517699115044, 'Lung': 11.966652249134947, 'Muscle': 8.27827397260274, 'Nerve': 8.369966074313409, 'Ovary': 7.8246722222222225, 'Pancreas': 3.302691463414634, 'Pituitary': 4.318572438162544, 'Prostate': 7.536297959183673, 'Salivary Gland': 5.702845679012346, 'Skin': 7.790623548922056, 'Small Intestine': 18.60670588235294, 'Spleen': 10.1797510373444, 'Stomach': 7.380064066852368, 'Testis': 5.030833795013851, 'Thyroid': 8.518555895865237, 'Uterus': 14.327035211267606, 'Vagina': 10.456467948717949}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[41.53, 37.78, 36.55, 43.17, 33.12, 48.41, 39.48, 39.08, 43.15, 34.65, 49.24, 39.56, 42.67, 36.89, 45.31, 40.55, 39.97, 42.13, 40.21, 39.32, 38.7, 39.44, 39.72, 35.14, 36.66, 34.09, 35.99, 36.23, 32.71, 37.73, 46.04, 37.17, 32.99, 36.69, 34.43, 32.98, 36.95, 31.63, 39.47, 33.85, 35.63, 33.99, 36.49, 33.75, 36.02, 40.76, 35.59, 36.08, 37.75, 33.05, 33.12, 38.27, 33.45, 34.87, 36.13, 29.99, 30.55, 30.99, 29.0, 31.46, 30.08, 31.4, 28.45, 34.21, 31.99, 33.93, 33.1, 34.17, 29.76, 36.23, 33.35, 37.95, 33.37, 38.67, 31.44, 36.63, 35.52, 29.77, 32.44, 29.64, 31.64, 27.68, 33.89, 32.01, 28.98, 28.42, 27.43, 27.33, 25.91, 28.96, 28.17, 27.59, 27.37, 27.93, 28.38, 27.01, 31.81, 26.91, 32.21, 28.99, 32.03, 32.39, 24.99, 30.41, 28.51, 34.57, 32.93, 38.9, 35.59, 34.97, 33.27, 34.28, 30.32, 37.69, 35.23, 39.3, 36.37, 32.87, 35.48, 34.63, 33.9, 35.2, 35.18, 33.63, 36.09, 32.71, 37.21, 30.78, 38.26, 41.38, 33.73, 39.09, 36.52, 42.76, 39.64, 39.61, 38.26, 41.01, 38.08, 44.97, 40.21, 41.56, 42.59, 34.21, 36.23, 40.63, 40.35, 44.35, 46.79, 56.02, 70.62, 87.35, 94.75, 96.67, 97.76, 97.96, 97.68, 97.4, 97.85, 98.14, 97.43, 96.81, 97.65, 96.98, 96.53, 97.0, 97.49, 97.62, 96.56, 97.54, 98.24, 97.5, 96.67, 98.08, 98.14, 98.16, 97.68, 98.04, 97.48, 97.86, 98.33, 98.34, 98.36, 98.53, 98.08, 97.57, 95.74, 97.38, 97.5, 97.9, 96.99, 95.75, 93.84, 93.76, 92.95, 92.44, 94.1, 95.98, 96.08, 96.88, 96.68, 97.28, 98.18, 98.02, 95.98, 95.6, 93.66, 95.65, 97.09, 98.06, 97.59, 97.14, 98.16, 97.66, 98.4, 98.55, 98.67, 98.75, 98.58, 98.67, 98.64, 98.84, 98.74, 98.56, 98.18, 96.76, 95.84, 95.0, 91.19, 90.35, 87.39, 87.54, 87.58, 92.91, 94.73, 97.7, 98.07, 98.43, 98.75, 98.72, 98.7, 98.35, 97.77, 97.51, 97.61, 98.07, 98.5, 98.69, 98.67, 98.58, 98.38, 98.3, 97.92, 97.01, 96.87, 95.08, 93.53, 92.53, 94.0, 95.49, 94.51, 94.0, 96.81, 96.67, 95.62, 97.8, 98.36, 98.0, 98.32, 98.47, 98.12, 98.18, 98.27, 97.76, 97.49, 97.42, 97.35, 95.1, 95.47, 96.02, 96.94, 97.69, 98.31, 98.53, 98.35, 98.34, 98.42, 98.04, 97.98, 98.33, 98.43, 98.22, 98.5, 97.98, 97.3, 98.41, 98.33, 98.61, 98.72, 98.68, 98.68, 97.89, 97.86, 97.36, 96.24, 95.63, 97.57, 98.28, 97.95, 97.09, 97.49, 98.18, 97.79, 96.48, 96.5, 98.08, 97.82, 97.68, 97.4, 97.73, 97.16, 96.38, 96.24, 96.68, 98.16, 97.37, 96.84, 98.24, 98.61, 98.14, 97.89, 98.76, 98.72, 98.28, 98.71, 98.81, 98.66, 98.48, 98.68, 98.57, 98.27, 98.42, 98.43, 98.6, 98.62, 98.58, 98.22, 97.93, 98.69, 98.56, 98.54, 97.37, 98.42, 98.67, 98.38, 98.12, 96.81, 94.02, 90.08, 88.82, 93.52, 94.36, 96.94, 98.55, 98.72, 98.71, 98.27, 95.87, 97.24, 94.02, 94.48, 97.09, 97.06, 97.49, 96.3, 94.71, 93.65, 91.24, 87.91, 89.71, 92.49, 94.64, 96.11, 98.11, 97.17, 98.34, 98.68, 98.84, 98.82, 98.84, 98.74, 98.63, 98.56, 98.62, 98.43, 97.8, 97.52, 96.52, 97.83, 98.19, 98.53, 98.78, 98.83, 98.88, 98.9, 98.95, 98.93, 98.93, 98.88, 98.92, 98.91, 98.88, 98.82, 98.79, 98.72, 98.65, 98.42, 98.43, 98.37, 98.62, 98.69, 98.64, 98.34, 98.11, 97.46, 97.81, 97.57, 98.04, 98.56, 98.73, 98.66, 98.71, 98.72, 98.79, 98.74, 98.75, 98.64, 98.6, 98.38, 98.28, 97.99, 97.62, 96.75, 96.92, 97.15, 97.93, 97.21, 97.26, 97.84, 97.67, 97.99, 98.15, 97.62, 98.02, 98.14, 97.93, 96.53, 93.91, 94.32, 95.12, 96.8, 97.9, 98.01, 97.74, 97.75, 96.29, 96.07, 95.67, 94.38, 95.53, 94.82, 95.29, 92.59, 94.55, 94.32, 95.63, 96.85, 96.17, 95.46, 96.19, 96.76, 96.46, 95.77, 95.34, 96.18, 96.04, 97.39, 97.98, 98.02, 98.02, 98.39, 98.23, 98.18, 97.77, 97.3, 97.99, 96.21, 96.64, 97.6, 98.09, 96.56, 94.95, 95.05, 93.66, 97.08, 97.3, 97.78, 98.23, 98.44, 98.5, 98.72, 98.74, 98.65, 98.79, 98.87, 98.85, 98.73, 98.74, 98.4, 98.47, 98.1, 98.45, 98.75, 98.73, 98.83, 98.66, 98.03, 98.45, 98.61, 97.59, 97.28, 98.32, 97.32, 97.67, 95.82, 88.28, 73.97, 61.87, 56.48, 51.01, 43.81, 44.9, 54.81, 52.45, 45.22, 43.56, 46.96, 41.16, 45.55, 41.59, 43.58, 38.27, 46.33, 43.75, 36.32, 41.97, 39.2, 41.44, 39.37, 44.53, 40.24, 43.62, 42.59, 45.73, 40.32, 35.49, 44.75, 43.82, 38.38, 40.52, 34.82, 32.85, 33.68, 33.4, 39.38, 35.44, 40.08, 52.12, 57.86, 65.11, 60.59, 57.04, 56.07, 48.6, 45.54, 41.26, 35.64, 38.07, 32.63, 36.58, 30.07, 32.26, 26.82, 28.25, 25.11, 28.09, 26.65, 25.19, 28.97, 28.89, 30.72]
|
[1.0, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 0.96, 0.96, 0.92, 0.94, 0.93, 0.98, 0.95, 0.98, 0.96, 0.95, 0.96, 0.87, 0.72, 0.88, 0.91, 0.8, 0.94, 0.83, 0.88, 0.86, 0.89, 0.88, 0.95, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 1.0, 0.94, 1.0, 0.88, 1.0, 0.9, 0.96, 0.99, 0.97, 0.89, 0.97, 0.96, 0.88, 0.96, 0.79, 0.9, 0.88, 0.86, 0.79, 0.81, 0.76, 0.87, 0.66, 0.98, 0.97, 0.93, 0.98, 0.93, 0.99, 0.99, 0.94, 0.92, 0.96, 0.9, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.92, 0.96, 0.85, 0.96, 0.96, 0.9, 0.91, 0.9, 0.87, 0.95, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 0.98, 1.0, 0.94, 0.98, 0.84, 0.93, 0.89, 0.91, 0.9, 0.94, 0.34, 0.29, 0.39, 0.07, 0.63, 0.47, 0.0, 0.14, 0.89, 0.76, 0.35, 0.5, 0.98, 0.56, 0.09, 0.1, 0.44, 0.21, 0.01, 0.22, 0.77, 0.11, 0.0, 0.54, 0.57, 0.18, 0.59, 0.4, 0.05, 0.28, 0.19, 0.09, 0.02, 0.32, 0.9, 0.18, 0.86, 0.2, 0.4, 0.7, 0.13, 0.72, 0.82, 0.98, 0.3, 0.88, 0.42, 0.21, 0.1, 0.27, 0.01, 0.08, 0.43, 0.87, 0.57, 0.15, 0.13, 0.07, 0.31, 0.19, 0.16, 0.68, 0.48, 0.04, 0.01, 0.0, 0.15, 0.0, 0.17, 0.02, 0.17, 0.05, 0.29, 0.37, 0.3, 0.43, 0.35, 0.6, 0.49, 0.61, 0.25, 0.05, 0.12, 0.18, 0.01, 0.23, 0.0, 0.27, 0.03, 0.22, 0.39, 0.56, 0.63, 0.48, 0.43, 0.0, 0.1, 0.0, 0.07, 0.03, 0.05, 0.18, 0.31, 0.34, 0.8, 0.57, 0.13, 0.26, 0.68, 0.18, 0.02, 0.47, 0.18, 0.03, 0.13, 0.42, 0.0, 0.05, 0.42, 0.36, 0.01, 0.5, 0.69, 0.46, 0.06, 0.85, 0.7, 0.37, 0.51, 0.08, 0.1, 0.03, 0.11, 0.11, 0.14, 0.43, 0.39, 0.47, 0.17, 0.6, 0.0, 0.08, 0.54, 0.0, 0.17, 0.0, 0.0, 0.01, 0.06, 0.26, 0.38, 0.17, 0.33, 0.3, 0.24, 0.0, 0.29, 0.28, 0.02, 0.02, 0.32, 0.38, 0.14, 0.78, 0.31, 0.77, 0.16, 0.03, 0.37, 0.15, 0.49, 0.12, 0.0, 0.17, 0.51, 0.0, 0.0, 0.46, 0.17, 0.0, 0.0, 0.31, 0.0, 0.04, 0.17, 0.12, 0.01, 0.3, 0.72, 0.17, 0.54, 0.01, 0.0, 0.0, 0.01, 0.11, 0.01, 0.13, 0.0, 0.32, 0.07, 0.0, 0.17, 0.01, 0.32, 0.66, 0.46, 0.24, 0.66, 0.28, 0.35, 0.0, 0.0, 0.0, 0.19, 0.24, 0.0, 0.15, 0.39, 0.05, 0.09, 0.11, 0.2, 0.84, 0.48, 0.32, 0.87, 0.35, 0.74, 0.51, 0.13, 0.09, 0.19, 0.18, 0.38, 0.05, 0.03, 0.0, 0.0, 0.01, 0.06, 0.02, 0.0, 0.23, 0.19, 0.82, 0.11, 0.1, 0.11, 0.26, 0.0, 0.05, 0.01, 0.0, 0.0, 0.0, 0.0, 0.01, 0.0, 0.0, 0.01, 0.02, 0.0, 0.15, 0.06, 0.02, 0.56, 0.28, 0.03, 0.0, 0.37, 0.02, 0.2, 0.49, 0.3, 0.33, 0.09, 0.0, 0.04, 0.03, 0.01, 0.0, 0.03, 0.12, 0.02, 0.22, 0.08, 0.38, 0.12, 0.55, 0.55, 0.76, 0.12, 0.07, 0.68, 0.59, 0.09, 0.86, 0.31, 0.06, 0.8, 0.7, 0.14, 0.09, 0.33, 0.97, 0.77, 0.29, 0.28, 0.03, 0.55, 0.21, 0.13, 0.56, 0.44, 0.38, 0.68, 0.51, 1.0, 0.77, 0.57, 0.37, 0.45, 0.37, 0.23, 0.44, 0.34, 0.14, 0.73, 0.11, 0.83, 0.75, 0.38, 0.62, 0.59, 0.06, 0.23, 0.34, 0.29, 0.68, 0.49, 0.27, 0.67, 0.14, 0.45, 0.67, 0.09, 0.05, 0.57, 0.67, 0.27, 0.87, 0.16, 0.64, 0.31, 0.0, 0.32, 0.4, 0.0, 0.0, 0.44, 0.28, 0.0, 0.03, 0.4, 0.09, 0.35, 0.18, 0.85, 0.67, 0.03, 0.04, 0.38, 0.05, 0.16, 0.46, 0.0, 0.24, 0.65, 0.07, 0.55, 0.0, 0.17, 0.72, 0.56, 0.9, 0.75, 0.92, 0.91, 0.86, 0.93, 0.83, 0.79, 0.89, 0.92, 0.83, 0.87, 0.83, 0.93, 0.96, 0.96, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 0.99, 1.0, 0.97, 1.0, 0.97, 0.96, 0.95, 0.71, 0.82, 0.83, 0.82, 0.84, 0.27, 0.51, 0.12, 0.61, 0.75, 0.15, 0.4, 0.52, 0.96, 0.83, 0.75, 0.74, 0.66, 0.91, 0.6, 0.89, 0.51, 0.86, 0.7, 0.7, 0.9, 0.71, 0.7, 0.68]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 75.737854
| 0.509484
| 1,249
|
O43255
|
Q92667
|
18323779, E3Net
|
UbiNet, UbiBrowser, 31181401
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
AKAP1
|
MAIQFRSLFPLALPGMLALLGWWWFFSRKKGHVSSHDEQQVEAGAVQLRADPAIKEPLPVEDVCPKVVSTPPSVTEPPEKELSTVSKLPAEPPALLQTHPPCRRSESSGILPNTTDMRLRPGTRRDDSTKLELALTGGEAKSIPLECPLSSPKGVLFSSKSAEVCKQDSPFSRVPRKVQPGYPVVPAEKRSSGERARETGGAEGTGDAVLGEKVLEEALLSREHVLELENSKGPSLASLEGEEDKGKSSSSQVVGPVQEEEYVAEKLPSRFIESAHTELAKDDAAPAPPVADAKAQDRGVEGELGNEESLDRNEEGLDRNEEGLDRNEESLDRNEEGLDRNEEIKRAAFQIISQVISEATEQVLATTVGKVAGRVCQASQLQGQKEESCVPVHQKTVLGPDTAEPATAEAAVAPPDAGLPLPGLPAEGSPPPKTYVSCLKSLLSSPTKDSKPNISAHHISLASCLALTTPSEELPDRAGILVEDATCVTCMSDSSQSVPLVASPGHCSDSFSTSGLEDSCTETSSSPRDKAITPPLPESTVPFSNGVLKGELSDLGAEDGWTMDAEADHSGGSDRNSMDSVDSCCSLKKTESFQNAQAGSNPKKVDLIIWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQSVQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVMPLSDDDQFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSYYTSL
|
Homo sapiens
|
Mitochondrion outer membrane, Mitochondrion
|
Tissue enhanced (skeletal)
|
{'Ciliated cells': '12.6', 'Basal respiratory cells': '10.9', 'Club cells': '35.6', 'Ionocytes': '10.7', 'Mucus glandular cells': '20.6', 'Serous glandular cells': '22.5', 'Gastric mucus-secreting cells': '53.6', 'Proximal enterocytes': '53.9', 'Paneth cells': '79.1', 'Distal enterocytes': '94.9', 'Intestinal goblet cells': '80.9', 'Exocrine glandular cells': '-0.507', 'Basal prostatic cells': '21.0', 'Prostatic glandular cells': '79.5', 'Breast glandular cells': '0.558', 'Breast myoepithelial cells': '0.477', 'Glandular and luminal cells': '38.2', 'Secretory cells': '13.8', 'Basal keratinocytes': '30.3', 'Suprabasal keratinocytes': '24.0', 'Basal squamous epithelial cells': '43.9', 'Squamous epithelial cells': '41.5', 'Alveolar cells type 1': '0.103', 'Alveolar cells type 2': '0.605', 'Salivary duct cells': '30.9', 'Ductal cells': '0.438', 'Hepatocytes': '0.520', 'Cholangiocytes': '30.5', 'Proximal tubular cells': '0.146', 'Distal tubular cells': '3.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.238', 'Sertoli cells': '-0.530', 'Granulosa cells': '9.8', 'Enteroendocrine cells': '68.5', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.574', 'Excitatory neurons': '14.4', 'Inhibitory neurons': '25.3', 'Cone photoreceptor cells': '49.3', 'Rod photoreceptor cells': '74.3', 'Bipolar cells': '37.7', 'Horizontal cells': '42.2', 'Astrocytes': '25.1', 'Oligodendrocyte precursor cells': '9.9', 'Oligodendrocytes': '9.0', 'Microglial cells': '4.5', 'Muller glia cells': '9.8', 'Schwann cells': '0.090', 'Spermatogonia': '-0.296', 'Spermatocytes': '0.000', 'Early spermatids': '0.575', 'Late spermatids': '0.837', 'Oocytes': '41.2', 'Cytotrophoblasts': '22.5', 'Syncytiotrophoblasts': '7.2', 'Extravillous trophoblasts': '11.8', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '14.7', 'Cardiomyocytes': '0.792', 'Skeletal myocytes': '0.222', 'Smooth muscle cells': '58.4', 'Adipocytes': '32.9', 'Melanocytes': '-0.086', 'Fibroblasts': '11.2', 'Peritubular cells': '-0.404', 'Endometrial stromal cells': '11.8', 'Ovarian stromal cells': '11.5', 'Undifferentiated cells': '93.2', 'T-cells': '14.0', 'B-cells': '14.1', 'Plasma cells': '11.0', 'Nk-cells': '9.3', 'Granulocytes': '13.9', 'Monocytes': '10.8', 'Macrophages': '12.8', 'Hofbauer cells': '7.3', 'Kupffer cells': '11.4', 'Dendritic cells': '11.3', 'Langerhans cells': '0.034', 'Erythroid cells': '-0.065', 'Adipocytes (Subcutaneous)': '-0.010', 'Adipocytes (Visceral)': '0.205', 'Breast glandular cells (progenitors)': '0.433', 'Adipocytes (Breast)': '-0.395', 'Colon enterocytes': '-0.097', 'Colon enteroendocrine cells': '0.038', 'Enteric glia cells': '-0.392', 'Mitotic cells (Colon)': '-0.007', 'Mitotic cells (Heart)': '0.316', 'Podocytes': '-0.185', 'Ascending Loop of Henle cells': '0.602', 'Intercalated cells': '0.023', 'Cholangiocyte': '0.018', 'NK-cells (Liver)': '-0.031', 'Respiratory ciliated cells': '-0.042', 'Mitotic cells (Lung)': '0.052', 'NK-cells (Lung)': '-0.427', 'B-cells (Lung)': '-0.353', 'Alpha cells': '0.397', 'Beta cells': '0.230', 'Prostate glandular cells': '0.195', 'Prostate basal glandular cells': '0.293', 'Urothelial cells': '-0.037', 'Keratinocyte (other)': '-0.164', 'Keratinocyte (granular)': '-0.195', 'Hair cortex cells': '0.254', 'Inner root sheath cells': '0.250', 'Outer root sheath cells': '0.386', 'Sebaceous gland cells': '0.384', 'Eccrine sweat gland cells': '0.400', 'Adipocytes (Skin)': '0.255', 'Mitotic cells (Skin)': '0.264', 'Parietal cells': '-0.401', 'Chief cells': '-0.572', 'Gastric mucous cells': '-0.276', 'Gastric enteroendocrine cells': '-0.509', 'Mitotic cells (Stomach)': '0.032', 'Parafollicular cells': '0.042', 'Thyroid glandular cells': '0.348', 'Mitotic cells (Thyroid)': '-0.080', 'Adrenal cortex cells': '0.361', 'Adrenal medulla cells': '0.033', 'Mitotic cells (Adrenal gland)': '0.103', 'Minor salivary glandular cells': '0.425', 'Minor salivary gland ductal cells': '0.099', 'Minor salivary gland basal cells': '0.335', 'Mitotic cells (Minor salivary gland)': '0.301', 'Adipocytes (Minor salivary gland)': '0.315', 'Somatotropes': '-0.005', 'Lactotropes': '0.085', 'Gonadotropes': '0.019', 'Corticotropes': '-0.044', 'Thyrotropes': '0.244', 'Undifferentiated cells (Pituitary gland)': '0.143', 'Mitotic cells (Spleen)': '-0.193', 'Platelets': '-0.247', 'Erythrocytes': '-0.258', 'Hematopoietic stem cells': '-0.365', 'B-cells (Spleen)': '0.551', 'NK-cells (Spleen)': '0.177', 'Amygdala excitatory': '29.5', 'Cerebellar inhibitory': '29.5', 'Cge interneuron': '37.3', 'Deep-layer corticothalamic and 6b': '18.6', 'Deep-layer intratelencephalic': '25.6', 'Deep-layer near-projecting': '19.0', 'Eccentric medium spiny neuron': '22.9', 'Hippocampal ca1-3': '27.0', 'Hippocampal ca4': '14.8', 'Hippocampal dentate gyrus': '16.5', 'Lamp5-lhx6 and chandelier': '37.0', 'Lower rhombic lip': '28.9', 'Mammillary body': '57.0', 'Medium spiny neuron': '48.1', 'Mge interneuron': '41.3', 'Midbrain-derived inhibitory': '15.5', 'Miscellaneous': '28.3', 'Splatter': '29.4', 'Thalamic excitatory': '26.1', 'Upper rhombic lip': '34.9', 'Upper-layer intratelencephalic': '26.1', 'Astrocyte': '55.9', 'Bergmann glia': '13.1', 'Central nervous system macrophage': '16.0', 'Choroid plexus epithelial cell': '21.6', 'Committed oligodendrocyte precursor': '18.3', 'Ependymal cell': '19.7', 'Oligodendrocyte': '14.9', 'Oligodendrocyte precursor cell': '19.0', 'Endothelial cell': '16.8', 'Pericyte': '85.3', 'Vascular associated smooth muscle cell': '86.6', 'Fibroblast': '62.6', 'Leukocyte': '13.9', 'Basophil': '1.6', 'Eosinophil': '0.4', 'Neutrophil': '0.5', 'Classical monocyte': '10.4', 'Non-classical monocyte': '9.6', 'Intermediate monocyte': '7.9', 'T-reg': '12.5', 'GdT-cell': '2.6', 'MAIT T-cell': '15.0', 'Memory CD4 T-cell': '2.1', 'Naive CD4 T-cell': '35.5', 'Memory CD8 T-cell': '2.1', 'Naive CD8 T-cell': '36.1', 'Memory B-cell': '1.8', 'Naive B-cell': '20.8', 'Plasmacytoid DC': '16.6', 'Myeloid DC': '18.9', 'NK-cell': '11.0', 'Total PBMC': '9.5', 'Vd2 gdTCR': '12.7', 'Memory CD4 T-cell Th1\\/Th17': '31.4', 'Memory CD4 T-cell Th17': '35.1', 'Memory CD4 T-cell Th2': '35.3', 'Non-Vd2 gdTCR': '6.1', 'Memory CD4 T-cell Th1': '33.4', 'Memory CD4 T-cell TFH': '39.6', 'Terminal effector memory CD4 T-cell': '15.2', 'Central memory CD8 T-cell': '10.8', 'Effector memory CD8 T-cell': '11.5', 'Terminal effector memory CD8 T-cell': '9.5', 'Non-switched memory B-cell': '10.8', 'Plasmablast': '19.9', 'Switched memory B-cell': '18.9', 'Exhausted memory B-cell': '13.4', 'Progenitor cell': '7.7', 'Memory T-reg': '34.2', 'Naive CD4 T-cell activated': '99.5', 'Naive CD8 T-cell activated': '103.1', 'Naive T-reg': '39.5'}
| null |
{'Adipose Tissue': 43.47952657807309, 'Adrenal Gland': 17.584155038759693, 'Bladder': 74.9342857142857, 'Blood': 6.974795156081809, 'Blood Vessel': 115.85351310861424, 'Brain': 24.067735427706285, 'Breast': 54.86581699346405, 'Cervix Uteri': 43.21052631578947, 'Colon': 97.90223491655968, 'Esophagus': 73.5046553633218, 'Fallopian Tube': 59.48222222222223, 'Heart': 44.96908524970964, 'Kidney': 18.247101123595503, 'Liver': 28.3245796460177, 'Lung': 31.94760553633218, 'Muscle': 76.67088418430885, 'Nerve': 34.58053311793215, 'Ovary': 35.24122222222222, 'Pancreas': 12.148932926829268, 'Pituitary': 28.19618374558304, 'Prostate': 58.0134693877551, 'Salivary Gland': 30.08703703703704, 'Skin': 32.58358651188502, 'Small Intestine': 58.31117647058824, 'Spleen': 16.511560165975105, 'Stomach': 64.59735376044569, 'Testis': 188.50742382271463, 'Thyroid': 68.7256967840735, 'Uterus': 48.460985915492955, 'Vagina': 42.56339743589744}
|
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0.52, 0.46, 0.5, 0.5, 0.68, 0.64, 0.6, 0.57, 0.59, 0.6, 0.47, 0.64, 0.54, 0.69, 0.62, 0.48, 0.43, 0.79, 0.62, 0.68, 0.75, 0.68, 0.84, 0.88, 0.9, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 0.99, 0.97, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 0.95, 0.99, 0.9, 0.95, 1.0, 0.93, 1.0, 1.0, 1.0, 0.98, 0.99, 0.99, 0.99, 0.95, 0.83, 0.92, 0.6, 0.96, 1.0, 0.99, 0.87, 1.0, 0.94, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.9, 0.99, 0.95, 0.98, 1.0, 0.97, 1.0, 0.98, 0.99, 1.0, 0.96, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.95, 1.0, 0.97, 1.0, 1.0, 1.0, 0.99, 1.0, 0.93, 0.95, 0.83, 0.89, 0.91, 0.95, 1.0, 1.0, 0.95, 1.0, 0.97, 1.0, 0.91, 1.0, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.99, 0.94, 0.94, 1.0, 0.9, 0.98, 0.81, 0.9, 0.74, 0.8, 0.92, 0.87, 0.94, 0.83, 0.91, 0.95, 0.91, 0.97, 0.96, 0.99, 1.0, 0.98, 1.0, 0.97, 1.0, 1.0, 0.95, 0.99, 0.98, 1.0, 0.93, 1.0, 0.82, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 0.91, 1.0, 0.92, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.98, 0.93, 0.9, 0.9, 0.9, 0.91, 0.7, 0.75, 0.66, 0.33, 0.54, 0.23, 0.12, 0.0, 0.51, 0.0, 0.31, 0.42, 0.74, 0.02, 0.07, 0.61, 0.48, 0.01, 0.37, 0.29, 0.89, 0.91, 0.17, 0.74, 0.14, 0.16, 0.52, 0.45, 0.01, 0.42, 0.87, 0.31, 0.04, 0.54, 0.06, 0.55, 0.01, 0.43, 0.27, 0.3, 0.71, 0.36, 0.94, 0.58, 0.32, 0.65, 0.69, 0.24, 0.18, 0.08, 0.01, 0.11, 0.0, 0.23, 0.08, 0.23, 0.45, 0.72, 0.35, 0.01, 0.35, 0.4, 0.0, 0.1, 0.52, 0.19, 0.0, 0.27, 0.71, 0.65, 0.04, 0.87, 0.6, 0.11, 0.68, 0.24, 0.59, 0.1, 0.37, 0.57, 0.41, 0.89, 0.59, 0.85, 0.95, 0.76, 0.97, 0.64, 0.49, 0.61, 0.81, 0.43, 0.31, 0.76, 0.5, 0.09, 0.22, 0.07, 0.6, 0.1, 0.31, 0.63, 0.5, 0.44, 0.5, 0.18, 0.4, 0.0, 0.23, 0.21, 0.32, 0.34, 0.27, 0.47, 0.31, 0.0, 0.11, 0.18, 0.0, 0.0, 0.01, 0.05, 0.09, 0.21, 0.63, 0.07, 0.69, 0.22, 0.27, 0.75, 0.4, 0.05, 0.74, 0.42, 0.08, 0.21, 0.53, 0.46, 0.01, 0.53, 0.68, 0.25, 0.02, 0.52, 0.63, 0.96, 0.92, 0.26, 0.59, 0.47, 0.07, 0.65, 0.78, 0.83, 0.17, 0.56, 0.4, 0.33, 0.3, 0.12, 0.0, 0.0, 0.0, 0.3, 0.26, 0.52, 0.98, 0.54, 0.26, 0.13, 0.23, 0.02, 0.0, 0.15, 0.01, 0.36, 0.23, 0.45, 0.35, 0.83, 1.0, 0.55, 0.44, 0.3, 0.02, 0.21, 0.0, 0.13, 0.07, 0.02, 0.03, 0.29, 0.09, 0.07, 0.39, 0.38, 0.6, 0.09, 0.54, 0.07, 0.59, 0.39, 0.0, 0.22, 0.46, 0.23, 0.48, 0.72, 0.51, 0.04, 0.25, 0.73, 0.16, 0.21, 0.01, 0.02, 0.06, 0.06, 0.1, 0.01, 0.25, 0.03, 0.06, 0.14, 0.11, 0.53, 0.19, 0.56, 0.37, 0.95, 0.73, 0.76, 0.67, 0.18, 0.4, 0.73, 0.67, 0.0, 0.25, 0.53, 0.05, 0.0, 0.48, 0.66, 0.15, 0.06, 0.51, 0.93, 0.36, 0.41, 0.0, 0.3, 0.03, 0.27, 0.07, 0.42, 0.45, 0.52, 0.17, 0.98, 0.78, 0.56, 0.23, 0.15, 0.19, 0.0, 0.23, 0.0, 0.21, 0.11, 0.44, 0.63, 0.82, 0.95, 0.69, 0.58, 0.39, 0.2, 0.01, 0.0, 0.53, 0.16, 0.0, 0.28, 0.64, 0.42, 0.58, 0.1, 0.04, 0.55, 0.38, 0.33, 0.54, 0.55, 0.85, 0.78, 0.77, 0.83, 0.85]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 55.993876
| 0.730543
| 642
|
O43255
|
Q92844
|
22199232, E3NethUbiquitome
|
UbiNet, UbiBrowser, 31181401
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
TANK
|
MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET
|
Homo sapiens
|
Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '48.0', 'Basal respiratory cells': '79.0', 'Club cells': '54.4', 'Ionocytes': '59.3', 'Mucus glandular cells': '39.1', 'Serous glandular cells': '24.7', 'Gastric mucus-secreting cells': '23.0', 'Proximal enterocytes': '30.9', 'Paneth cells': '43.0', 'Distal enterocytes': '39.0', 'Intestinal goblet cells': '29.4', 'Exocrine glandular cells': '-0.672', 'Basal prostatic cells': '43.3', 'Prostatic glandular cells': '27.8', 'Breast glandular cells': '0.585', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '51.4', 'Secretory cells': '89.1', 'Basal keratinocytes': '45.1', 'Suprabasal keratinocytes': '50.4', 'Basal squamous epithelial cells': '25.7', 'Squamous epithelial cells': '28.2', 'Alveolar cells type 1': '0.173', 'Alveolar cells type 2': '-0.317', 'Salivary duct cells': '44.2', 'Ductal cells': '0.645', 'Hepatocytes': '0.240', 'Cholangiocytes': '42.0', 'Proximal tubular cells': '0.173', 'Distal tubular cells': '46.1', 'Collecting duct cells': '37.0', 'Mesothelial cells': '0.228', 'Sertoli cells': '0.324', 'Granulosa cells': '31.1', 'Enteroendocrine cells': '33.2', 'Pancreatic endocrine cells': '32.3', 'Leydig cells': '0.442', 'Excitatory neurons': '48.2', 'Inhibitory neurons': '58.3', 'Cone photoreceptor cells': '34.0', 'Rod photoreceptor cells': '28.5', 'Bipolar cells': '28.6', 'Horizontal cells': '17.0', 'Astrocytes': '78.0', 'Oligodendrocyte precursor cells': '59.4', 'Oligodendrocytes': '81.3', 'Microglial cells': '115.4', 'Muller glia cells': '34.2', 'Schwann cells': '0.125', 'Spermatogonia': '0.459', 'Spermatocytes': '0.453', 'Early spermatids': '0.024', 'Late spermatids': '-0.500', 'Oocytes': '34.6', 'Cytotrophoblasts': '42.5', 'Syncytiotrophoblasts': '156.2', 'Extravillous trophoblasts': '91.8', 'Endothelial cells': '38.1', 'Lymphatic endothelial cells': '52.3', 'Cardiomyocytes': '0.529', 'Skeletal myocytes': '-0.323', 'Smooth muscle cells': '37.9', 'Adipocytes': '34.2', 'Melanocytes': '-0.045', 'Fibroblasts': '59.1', 'Peritubular cells': '0.405', 'Endometrial stromal cells': '41.7', 'Ovarian stromal cells': '39.3', 'Undifferentiated cells': '30.1', 'T-cells': '91.3', 'B-cells': '105.5', 'Plasma cells': '47.4', 'Nk-cells': '48.0', 'Granulocytes': '97.9', 'Monocytes': '285.3', 'Macrophages': '108.3', 'Hofbauer cells': '53.6', 'Kupffer cells': '65.1', 'Dendritic cells': '39.8', 'Langerhans cells': '0.153', 'Erythroid cells': '0.110', 'Adipocytes (Subcutaneous)': '0.109', 'Adipocytes (Visceral)': '-0.087', 'Breast glandular cells (progenitors)': '0.519', 'Adipocytes (Breast)': '-0.579', 'Colon enterocytes': '-0.122', 'Colon enteroendocrine cells': '0.302', 'Enteric glia cells': '0.043', 'Mitotic cells (Colon)': '0.077', 'Mitotic cells (Heart)': '0.495', 'Podocytes': '-0.034', 'Ascending Loop of Henle cells': '0.352', 'Intercalated cells': '-0.069', 'Cholangiocyte': '0.274', 'NK-cells (Liver)': '-0.144', 'Respiratory ciliated cells': '0.030', 'Mitotic cells (Lung)': '-0.149', 'NK-cells (Lung)': '0.406', 'B-cells (Lung)': '0.201', 'Alpha cells': '0.405', 'Beta cells': '0.217', 'Prostate glandular cells': '-0.509', 'Prostate basal glandular cells': '0.028', 'Urothelial cells': '0.240', 'Keratinocyte (other)': '0.004', 'Keratinocyte (granular)': '-0.246', 'Hair cortex cells': '0.005', 'Inner root sheath cells': '0.090', 'Outer root sheath cells': '0.327', 'Sebaceous gland cells': '0.119', 'Eccrine sweat gland cells': '0.169', 'Adipocytes (Skin)': '-0.015', 'Mitotic cells (Skin)': '0.227', 'Parietal cells': '-0.701', 'Chief cells': '-0.631', 'Gastric mucous cells': '-0.420', 'Gastric enteroendocrine cells': '-0.452', 'Mitotic cells (Stomach)': '-0.008', 'Parafollicular cells': '0.051', 'Thyroid glandular cells': '0.191', 'Mitotic cells (Thyroid)': '0.111', 'Adrenal cortex cells': '0.569', 'Adrenal medulla cells': '0.028', 'Mitotic cells (Adrenal gland)': '0.306', 'Minor salivary glandular cells': '0.705', 'Minor salivary gland ductal cells': '0.222', 'Minor salivary gland basal cells': '0.267', 'Mitotic cells (Minor salivary gland)': '0.342', 'Adipocytes (Minor salivary gland)': '0.236', 'Somatotropes': '-0.171', 'Lactotropes': '-0.365', 'Gonadotropes': '-0.200', 'Corticotropes': '-0.141', 'Thyrotropes': '-0.071', 'Undifferentiated cells (Pituitary gland)': '0.418', 'Mitotic cells (Spleen)': '-0.123', 'Platelets': '-0.004', 'Erythrocytes': '-0.033', 'Hematopoietic stem cells': '-0.075', 'B-cells (Spleen)': '0.329', 'NK-cells (Spleen)': '0.297', 'Amygdala excitatory': '76.4', 'Cerebellar inhibitory': '110.0', 'Cge interneuron': '65.9', 'Deep-layer corticothalamic and 6b': '86.1', 'Deep-layer intratelencephalic': '63.5', 'Deep-layer near-projecting': '93.6', 'Eccentric medium spiny neuron': '153.6', 'Hippocampal ca1-3': '91.5', 'Hippocampal ca4': '35.7', 'Hippocampal dentate gyrus': '46.3', 'Lamp5-lhx6 and chandelier': '75.8', 'Lower rhombic lip': '87.0', 'Mammillary body': '106.9', 'Medium spiny neuron': '130.5', 'Mge interneuron': '97.0', 'Midbrain-derived inhibitory': '83.4', 'Miscellaneous': '91.4', 'Splatter': '110.5', 'Thalamic excitatory': '82.7', 'Upper rhombic lip': '88.8', 'Upper-layer intratelencephalic': '48.4', 'Astrocyte': '169.0', 'Bergmann glia': '103.4', 'Central nervous system macrophage': '258.1', 'Choroid plexus epithelial cell': '127.0', 'Committed oligodendrocyte precursor': '85.7', 'Ependymal cell': '94.6', 'Oligodendrocyte': '133.0', 'Oligodendrocyte precursor cell': '109.2', 'Endothelial cell': '271.4', 'Pericyte': '122.9', 'Vascular associated smooth muscle cell': '101.7', 'Fibroblast': '419.0', 'Leukocyte': '282.0', 'Basophil': '302.9', 'Eosinophil': '97.5', 'Neutrophil': '673.4', 'Classical monocyte': '49.6', 'Non-classical monocyte': '78.6', 'Intermediate monocyte': '293.2', 'T-reg': '166.5', 'GdT-cell': '36.1', 'MAIT T-cell': '172.9', 'Memory CD4 T-cell': '59.0', 'Naive CD4 T-cell': '37.8', 'Memory CD8 T-cell': '53.1', 'Naive CD8 T-cell': '26.7', 'Memory B-cell': '64.0', 'Naive B-cell': '108.2', 'Plasmacytoid DC': '156.8', 'Myeloid DC': '216.8', 'NK-cell': '32.6', 'Total PBMC': '187.0', 'Vd2 gdTCR': '123.3', 'Memory CD4 T-cell Th1\\/Th17': '71.7', 'Memory CD4 T-cell Th17': '58.0', 'Memory CD4 T-cell Th2': '48.3', 'Non-Vd2 gdTCR': '143.5', 'Memory CD4 T-cell Th1': '51.7', 'Memory CD4 T-cell TFH': '46.0', 'Terminal effector memory CD4 T-cell': '138.8', 'Central memory CD8 T-cell': '175.8', 'Effector memory CD8 T-cell': '184.9', 'Terminal effector memory CD8 T-cell': '139.1', 'Non-switched memory B-cell': '224.7', 'Plasmablast': '148.7', 'Switched memory B-cell': '228.2', 'Exhausted memory B-cell': '189.2', 'Progenitor cell': '70.3', 'Memory T-reg': '51.1', 'Naive CD4 T-cell activated': '67.2', 'Naive CD8 T-cell activated': '54.0', 'Naive T-reg': '45.8'}
|
1KZZ, 1L0A, 5H10
|
{'Adipose Tissue': 24.90334219269103, 'Adrenal Gland': 14.950581395348838, 'Bladder': 23.382380952380952, 'Blood': 18.28330979547901, 'Blood Vessel': 23.424843445692886, 'Brain': 8.23006056018168, 'Breast': 28.856479302832245, 'Cervix Uteri': 19.431578947368426, 'Colon': 16.567102695763797, 'Esophagus': 16.077761937716264, 'Fallopian Tube': 23.55777777777778, 'Heart': 6.422700696864112, 'Kidney': 8.38120224719101, 'Liver': 9.671495575221238, 'Lung': 28.75728373702422, 'Muscle': 16.07690784557908, 'Nerve': 23.530613893376415, 'Ovary': 19.421611111111112, 'Pancreas': 5.048673780487805, 'Pituitary': 16.7013074204947, 'Prostate': 15.761828571428572, 'Salivary Gland': 16.279512345679013, 'Skin': 23.837815367606417, 'Small Intestine': 18.270818181818186, 'Spleen': 21.923340248962653, 'Stomach': 12.006437325905292, 'Testis': 11.415581717451522, 'Thyroid': 21.969108728943336, 'Uterus': 20.779366197183094, 'Vagina': 20.83201923076923}
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[53.29, 69.58, 71.3, 82.64, 90.49, 91.24, 93.76, 94.06, 95.25, 94.67, 96.78, 97.43, 97.56, 98.11, 98.36, 98.16, 98.43, 98.39, 98.56, 98.18, 98.48, 98.52, 98.47, 98.39, 98.38, 98.43, 98.43, 98.39, 98.12, 98.5, 98.41, 98.48, 98.28, 98.33, 98.33, 98.5, 98.39, 98.27, 98.51, 98.34, 98.2, 98.4, 98.42, 98.54, 98.11, 98.1, 98.17, 98.08, 97.93, 98.25, 98.45, 97.96, 98.11, 98.1, 97.9, 97.41, 97.82, 97.79, 96.98, 95.16, 96.01, 95.14, 93.24, 91.1, 90.53, 85.72, 77.45, 70.51, 57.9, 54.93, 53.9, 53.68, 51.71, 42.3, 45.14, 49.59, 44.23, 49.81, 44.44, 46.65, 39.14, 45.81, 39.66, 42.35, 42.3, 40.99, 44.1, 37.22, 39.7, 37.22, 37.9, 37.91, 36.34, 40.43, 45.38, 36.7, 43.96, 41.07, 44.79, 41.01, 35.71, 45.74, 42.93, 41.67, 46.04, 47.42, 37.76, 41.54, 38.96, 48.52, 40.78, 41.24, 38.28, 37.26, 38.67, 40.56, 39.55, 38.36, 46.02, 40.13, 44.28, 39.71, 35.96, 41.6, 37.83, 40.64, 48.93, 47.15, 51.42, 57.54, 59.04, 61.31, 75.74, 81.55, 88.35, 90.34, 91.45, 93.65, 94.8, 94.96, 95.87, 97.21, 96.99, 96.74, 97.84, 97.12, 97.14, 97.34, 97.69, 97.53, 97.92, 97.85, 97.18, 97.02, 97.92, 96.89, 96.42, 95.26, 94.9, 94.85, 93.96, 93.08, 91.47, 87.93, 88.68, 84.24, 65.86, 64.94, 63.79, 53.31, 49.44, 46.66, 48.96, 48.4, 54.91, 52.14, 55.86, 70.52, 75.59, 73.05, 67.19, 70.19, 69.17, 69.67, 61.96, 65.58, 57.73, 47.75, 51.85, 45.97, 40.64, 44.42, 38.39, 38.38, 46.13, 37.6, 38.66, 41.1, 43.13, 44.53, 45.83, 49.83, 45.2, 43.48, 38.76, 44.68, 43.06, 43.33, 38.66, 39.72, 37.01, 48.81, 42.51, 41.19, 47.29, 43.34, 42.21, 33.66, 39.69, 39.53, 43.91, 41.91, 44.0, 34.5, 42.28, 45.53, 45.92, 43.27, 53.44, 54.4, 57.64, 51.33, 53.75, 58.06, 70.78, 59.9, 65.33, 63.26, 63.93, 56.45, 59.86, 50.98, 49.17, 57.98, 58.44, 53.26, 43.47, 43.1, 50.39, 51.99, 45.66, 43.77, 47.67, 42.33, 40.67, 40.34, 30.67, 39.89, 36.1, 38.99, 40.46, 40.49, 39.18, 41.68, 38.99, 36.66, 35.14, 37.21, 37.76, 34.3, 45.62, 35.81, 38.4, 43.06, 35.6, 40.45, 37.39, 47.82, 33.94, 39.46, 40.85, 37.74, 43.14, 37.4, 32.68, 38.71, 33.55, 38.21, 34.33, 42.62, 36.83, 32.16, 40.88, 42.72, 42.26, 43.22, 35.91, 38.72, 38.31, 40.38, 44.41, 40.9, 39.94, 41.04, 43.9, 41.43, 41.98, 44.51, 42.85, 38.58, 37.83, 46.03, 35.98, 40.13, 43.06, 34.65, 44.0, 35.5, 45.39, 37.01, 44.48, 38.71, 44.54, 35.5, 40.27, 37.15, 39.52, 35.36, 37.71, 38.34, 41.72, 37.19, 36.18, 37.6, 37.62, 41.59, 38.02, 37.88, 38.61, 30.0, 37.9, 31.26, 46.67, 38.81, 39.78, 35.25, 39.37, 51.04, 42.63, 45.09, 48.72, 34.89, 48.32, 37.33, 42.67, 40.43, 40.05, 43.52, 44.28, 43.14, 49.28, 45.64, 59.65, 67.33, 67.04, 61.96, 60.48, 68.36, 63.76, 53.0, 62.33, 61.8, 43.9, 49.63, 40.94, 45.03, 44.01, 38.26, 37.89, 39.72, 40.9, 38.97, 37.88, 33.48, 36.15, 38.68, 45.56, 50.17, 50.86, 54.09, 53.16, 61.72, 64.22, 74.18, 83.88, 87.84, 85.28, 85.61, 88.21, 87.08, 85.62, 84.66, 84.7, 80.29, 71.93, 66.46, 69.25, 76.71, 82.45, 84.49, 85.39, 85.74, 88.33, 88.73, 88.3, 89.97, 88.91, 86.71, 87.58, 88.91, 83.29, 76.66, 66.94, 58.53, 52.75]
|
[0.95, 0.76, 0.88, 0.47, 0.54, 0.58, 0.67, 0.53, 0.61, 0.54, 0.74, 0.49, 0.56, 0.45, 0.54, 0.64, 0.44, 0.49, 0.5, 0.28, 0.58, 0.5, 0.67, 0.54, 0.44, 0.39, 0.56, 0.7, 0.62, 0.63, 0.54, 0.66, 0.54, 0.45, 0.49, 0.43, 0.49, 0.49, 0.47, 0.55, 0.49, 0.56, 0.51, 0.59, 0.59, 0.7, 0.57, 0.62, 0.49, 0.6, 0.48, 0.5, 0.62, 0.49, 0.45, 0.46, 0.63, 0.57, 0.55, 0.52, 0.5, 0.61, 0.66, 0.67, 0.59, 0.43, 0.57, 0.64, 0.62, 0.79, 0.84, 0.87, 0.81, 1.0, 0.93, 0.94, 0.95, 0.86, 0.9, 0.85, 0.83, 0.86, 0.93, 0.98, 0.98, 1.0, 0.94, 1.0, 1.0, 1.0, 1.0, 0.96, 0.96, 0.92, 0.95, 0.99, 0.99, 0.96, 0.99, 0.96, 1.0, 1.0, 0.99, 0.99, 1.0, 0.97, 0.96, 0.93, 0.92, 0.97, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.99, 0.96, 0.93, 0.95, 0.89, 0.99, 0.91, 0.9, 0.77, 0.86, 0.75, 0.61, 0.77, 0.75, 0.74, 0.64, 0.55, 0.7, 0.45, 0.44, 0.56, 0.51, 0.62, 0.54, 0.66, 0.56, 0.48, 0.58, 0.54, 0.55, 0.51, 0.58, 0.63, 0.41, 0.57, 0.46, 0.53, 0.61, 0.47, 0.6, 0.38, 0.62, 0.71, 0.52, 0.61, 0.65, 0.65, 0.73, 0.62, 0.81, 0.84, 0.69, 0.9, 0.69, 0.86, 0.77, 0.86, 0.79, 0.85, 0.86, 0.76, 0.87, 0.88, 0.78, 0.78, 0.84, 0.58, 0.88, 0.89, 0.86, 0.97, 0.98, 1.0, 1.0, 0.96, 0.95, 0.97, 0.94, 0.97, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.93, 0.94, 0.87, 0.93, 0.89, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.98, 0.89, 0.99, 0.81, 0.96, 0.76, 0.64, 0.84, 0.78, 0.77, 0.79, 0.85, 0.6, 0.9, 0.86, 0.93, 0.67, 0.96, 0.57, 0.95, 0.8, 0.65, 0.74, 0.94, 0.95, 0.77, 0.89, 0.89, 0.9, 0.89, 0.94, 0.92, 0.88, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.95, 0.91, 0.93, 0.87, 0.83, 0.92, 0.86, 0.94, 0.96, 0.98, 0.98, 0.91, 0.9, 0.97, 0.88, 1.0, 1.0, 1.0, 1.0, 0.9, 0.94, 0.87, 0.92, 0.91, 0.97, 0.98, 0.98, 0.94, 0.95, 0.93, 0.91, 0.92, 0.97, 1.0, 0.99, 1.0, 0.93, 1.0, 0.9, 0.93, 0.98, 0.95, 0.98, 0.99, 0.96, 0.95, 0.96, 0.98, 0.99, 0.99, 0.86, 0.89, 0.86, 0.9, 0.95, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.82, 0.93, 0.91, 0.93, 0.81, 0.93, 0.9, 0.81, 0.8, 0.69, 0.9, 0.9, 0.97, 0.96, 0.98, 0.99, 0.99, 1.0, 0.9, 0.98, 0.95, 0.97, 0.83, 1.0, 0.92, 0.97, 0.99, 0.88, 0.98, 0.8, 0.96, 0.85, 0.78, 0.89, 0.79, 0.88, 0.88, 0.77, 0.87, 0.68, 0.68, 0.83, 0.77, 0.61, 0.84, 0.91, 0.36, 0.86, 0.95, 0.83, 0.82, 0.87, 0.82, 0.65, 0.59, 0.64, 0.64, 0.52, 0.5, 0.81, 0.63, 0.56, 0.26, 0.51, 0.01, 0.92, 0.6, 0.52, 0.75, 0.26, 0.6, 0.14, 0.32, 0.43, 0.92, 0.84, 0.28, 0.53, 0.64, 0.48, 0.29, 0.13, 0.49, 0.67, 0.19, 0.23, 0.51, 0.22, 0.26, 0.7, 0.69, 0.7, 0.75, 0.73]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 59.589576
| 0.788071
| 1,867
|
O43255
|
Q96B97
|
22199232, hUbiquitome
|
UbiNet, UbiBrowser, 31181401
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
SH3KBP1
|
MVEAIVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKEMKKDPLTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDELGISQDEQLSKSSLRETTGSESDGGDSSSTKSEGANGTVATAAIQPKKVKGVGFGDIFKDKPIKLRPRSIEVENDFLPVEKTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEKEGNRPKKPPPPSAPVIKQGAGTTERKHEIKKIPPERPEMLPNRTEEKERPEREPKLDLQKPSVPAIPPKKPRPPKTNSLSRPGALPPRRPERPVGPLTHTRGDSPKIDLAGSSLSGILDKDLSDRSNDIDLEGFDSVVSSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPDIFDSPSPEEDKEEHISLAHRGVDASKKTSKTVTISQVSDNKASLPPKPGTMAAGGGGPAPLSSAAPSPLSSSLGTAGHRANSPSLFGTEGKPKMEPAASSQAAVEELRTQVRELRSIIETMKDQQKREIKQLLSELDEEKKIRLRLQMEVNDIKKALQSK
|
Homo sapiens
|
Cytoplasm, Cytoplasm, cytoskeleton, Cytoplasmic vesicle membrane, Synapse, synaptosome, Cell junction, focal adhesion
|
Low tissue specificity
|
{'Ciliated cells': '10.5', 'Basal respiratory cells': '7.8', 'Club cells': '15.9', 'Ionocytes': '14.0', 'Mucus glandular cells': '13.4', 'Serous glandular cells': '29.0', 'Gastric mucus-secreting cells': '19.5', 'Proximal enterocytes': '22.1', 'Paneth cells': '149.1', 'Distal enterocytes': '195.9', 'Intestinal goblet cells': '32.5', 'Exocrine glandular cells': '-0.484', 'Basal prostatic cells': '3.7', 'Prostatic glandular cells': '3.5', 'Breast glandular cells': '-0.430', 'Breast myoepithelial cells': '-0.530', 'Glandular and luminal cells': '8.0', 'Secretory cells': '13.6', 'Basal keratinocytes': '9.2', 'Suprabasal keratinocytes': '4.9', 'Basal squamous epithelial cells': '4.7', 'Squamous epithelial cells': '1.3', 'Alveolar cells type 1': '0.189', 'Alveolar cells type 2': '-0.304', 'Salivary duct cells': '13.6', 'Ductal cells': '0.653', 'Hepatocytes': '0.496', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.272', 'Distal tubular cells': '0.0', 'Collecting duct cells': '7.8', 'Mesothelial cells': '-0.174', 'Sertoli cells': '0.463', 'Granulosa cells': '6.9', 'Enteroendocrine cells': '57.6', 'Pancreatic endocrine cells': '37.4', 'Leydig cells': '0.656', 'Excitatory neurons': '69.8', 'Inhibitory neurons': '121.0', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '1.7', 'Bipolar cells': '4.8', 'Horizontal cells': '12.0', 'Astrocytes': '5.3', 'Oligodendrocyte precursor cells': '81.6', 'Oligodendrocytes': '135.9', 'Microglial cells': '103.8', 'Muller glia cells': '5.9', 'Schwann cells': '0.090', 'Spermatogonia': '0.569', 'Spermatocytes': '0.246', 'Early spermatids': '-0.442', 'Late spermatids': '-0.609', 'Oocytes': '76.5', 'Cytotrophoblasts': '24.8', 'Syncytiotrophoblasts': '23.1', 'Extravillous trophoblasts': '40.8', 'Endothelial cells': '20.0', 'Lymphatic endothelial cells': '21.5', 'Cardiomyocytes': '0.682', 'Skeletal myocytes': '0.436', 'Smooth muscle cells': '48.8', 'Adipocytes': '36.9', 'Melanocytes': '0.071', 'Fibroblasts': '50.7', 'Peritubular cells': '0.655', 'Endometrial stromal cells': '29.2', 'Ovarian stromal cells': '10.5', 'Undifferentiated cells': '32.3', 'T-cells': '130.1', 'B-cells': '84.5', 'Plasma cells': '62.9', 'Nk-cells': '160.6', 'Granulocytes': '135.1', 'Monocytes': '135.9', 'Macrophages': '112.8', 'Hofbauer cells': '71.4', 'Kupffer cells': '73.9', 'Dendritic cells': '203.8', 'Langerhans cells': '0.373', 'Erythroid cells': '-0.055', 'Adipocytes (Subcutaneous)': '0.709', 'Adipocytes (Visceral)': '0.578', 'Breast glandular cells (progenitors)': '-0.361', 'Adipocytes (Breast)': '0.748', 'Colon enterocytes': '0.201', 'Colon enteroendocrine cells': '0.214', 'Enteric glia cells': '0.350', 'Mitotic cells (Colon)': '0.353', 'Mitotic cells (Heart)': '0.337', 'Podocytes': '0.090', 'Ascending Loop of Henle cells': '0.351', 'Intercalated cells': '0.114', 'Cholangiocyte': '0.387', 'NK-cells (Liver)': '-0.107', 'Respiratory ciliated cells': '-0.044', 'Mitotic cells (Lung)': '0.098', 'NK-cells (Lung)': '0.380', 'B-cells (Lung)': '0.149', 'Alpha cells': '0.460', 'Beta cells': '0.259', 'Prostate glandular cells': '-0.487', 'Prostate basal glandular cells': '-0.244', 'Urothelial cells': '0.024', 'Keratinocyte (other)': '0.261', 'Keratinocyte (granular)': '0.464', 'Hair cortex cells': '-0.216', 'Inner root sheath cells': '-0.263', 'Outer root sheath cells': '-0.231', 'Sebaceous gland cells': '-0.016', 'Eccrine sweat gland cells': '-0.130', 'Adipocytes (Skin)': '-0.076', 'Mitotic cells (Skin)': '0.002', 'Parietal cells': '-0.637', 'Chief cells': '-0.463', 'Gastric mucous cells': '-0.299', 'Gastric enteroendocrine cells': '-0.261', 'Mitotic cells (Stomach)': '0.123', 'Parafollicular cells': '0.033', 'Thyroid glandular cells': '0.412', 'Mitotic cells (Thyroid)': '0.268', 'Adrenal cortex cells': '0.559', 'Adrenal medulla cells': '-0.019', 'Mitotic cells (Adrenal gland)': '0.361', 'Minor salivary glandular cells': '0.395', 'Minor salivary gland ductal cells': '0.151', 'Minor salivary gland basal cells': '0.082', 'Mitotic cells (Minor salivary gland)': '0.271', 'Adipocytes (Minor salivary gland)': '0.346', 'Somatotropes': '-0.272', 'Lactotropes': '-0.055', 'Gonadotropes': '-0.101', 'Corticotropes': '0.541', 'Thyrotropes': '0.464', 'Undifferentiated cells (Pituitary gland)': '0.095', 'Mitotic cells (Spleen)': '-0.016', 'Platelets': '-0.073', 'Erythrocytes': '-0.125', 'Hematopoietic stem cells': '-0.104', 'B-cells (Spleen)': '0.512', 'NK-cells (Spleen)': '0.372', 'Amygdala excitatory': '174.2', 'Cerebellar inhibitory': '24.9', 'Cge interneuron': '180.8', 'Deep-layer corticothalamic and 6b': '127.6', 'Deep-layer intratelencephalic': '150.2', 'Deep-layer near-projecting': '115.8', 'Eccentric medium spiny neuron': '209.8', 'Hippocampal ca1-3': '121.6', 'Hippocampal ca4': '164.4', 'Hippocampal dentate gyrus': '117.4', 'Lamp5-lhx6 and chandelier': '262.3', 'Lower rhombic lip': '94.5', 'Mammillary body': '138.3', 'Medium spiny neuron': '215.1', 'Mge interneuron': '194.2', 'Midbrain-derived inhibitory': '126.8', 'Miscellaneous': '145.2', 'Splatter': '150.3', 'Thalamic excitatory': '263.2', 'Upper rhombic lip': '13.5', 'Upper-layer intratelencephalic': '155.3', 'Astrocyte': '8.5', 'Bergmann glia': '26.9', 'Central nervous system macrophage': '832.2', 'Choroid plexus epithelial cell': '479.4', 'Committed oligodendrocyte precursor': '162.8', 'Ependymal cell': '13.7', 'Oligodendrocyte': '266.9', 'Oligodendrocyte precursor cell': '193.3', 'Endothelial cell': '70.9', 'Pericyte': '376.2', 'Vascular associated smooth muscle cell': '245.0', 'Fibroblast': '52.9', 'Leukocyte': '538.6', 'Basophil': '121.0', 'Eosinophil': '109.1', 'Neutrophil': '371.2', 'Classical monocyte': '139.9', 'Non-classical monocyte': '106.8', 'Intermediate monocyte': '153.8', 'T-reg': '176.8', 'GdT-cell': '117.0', 'MAIT T-cell': '146.8', 'Memory CD4 T-cell': '117.8', 'Naive CD4 T-cell': '104.4', 'Memory CD8 T-cell': '131.1', 'Naive CD8 T-cell': '73.0', 'Memory B-cell': '35.7', 'Naive B-cell': '51.3', 'Plasmacytoid DC': '465.5', 'Myeloid DC': '220.0', 'NK-cell': '159.6', 'Total PBMC': '168.8', 'Vd2 gdTCR': '191.6', 'Memory CD4 T-cell Th1\\/Th17': '117.7', 'Memory CD4 T-cell Th17': '133.0', 'Memory CD4 T-cell Th2': '148.6', 'Non-Vd2 gdTCR': '194.0', 'Memory CD4 T-cell Th1': '129.3', 'Memory CD4 T-cell TFH': '160.9', 'Terminal effector memory CD4 T-cell': '181.5', 'Central memory CD8 T-cell': '193.2', 'Effector memory CD8 T-cell': '247.0', 'Terminal effector memory CD8 T-cell': '206.4', 'Non-switched memory B-cell': '130.0', 'Plasmablast': '122.2', 'Switched memory B-cell': '96.0', 'Exhausted memory B-cell': '126.0', 'Progenitor cell': '124.4', 'Memory T-reg': '163.0', 'Naive CD4 T-cell activated': '69.6', 'Naive CD8 T-cell activated': '66.6', 'Naive T-reg': '133.8'}
|
2BZ8, 2K6D, 2K9G, 2N64, 2O2O, 2YDL, 5ABS
|
{'Adipose Tissue': 38.56872093023256, 'Adrenal Gland': 7.526170542635659, 'Bladder': 11.447714285714286, 'Blood': 68.20107750269106, 'Blood Vessel': 13.357195505617977, 'Brain': 13.796981718395154, 'Breast': 31.56347276688453, 'Cervix Uteri': 19.48078947368421, 'Colon': 13.391890885750962, 'Esophagus': 8.17265107266436, 'Fallopian Tube': 12.632555555555555, 'Heart': 10.408828803716608, 'Kidney': 7.832359550561798, 'Liver': 3.8713734513274334, 'Lung': 31.113183391003457, 'Muscle': 3.342516313823163, 'Nerve': 29.96442649434572, 'Ovary': 9.809855555555556, 'Pancreas': 1.7983560975609758, 'Pituitary': 16.59386925795053, 'Prostate': 8.556118367346938, 'Salivary Gland': 8.834820987654322, 'Skin': 31.35004311774461, 'Small Intestine': 19.368122994652406, 'Spleen': 27.856307053941908, 'Stomach': 8.11348746518106, 'Testis': 5.385180055401662, 'Thyroid': 21.857137825421137, 'Uterus': 12.458401408450705, 'Vagina': 16.258070512820513}
|
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|
[67.4, 87.04, 93.08, 93.64, 94.74, 95.8, 94.78, 94.62, 94.94, 95.34, 94.88, 93.19, 91.59, 90.55, 89.52, 92.19, 94.65, 92.51, 94.64, 94.81, 94.92, 95.0, 91.46, 94.63, 94.1, 94.22, 93.75, 91.29, 93.39, 90.8, 90.02, 80.66, 75.09, 83.4, 90.09, 93.35, 94.91, 94.19, 94.57, 94.3, 92.06, 88.01, 88.19, 90.84, 92.9, 94.1, 94.56, 95.08, 94.24, 93.63, 94.77, 94.67, 94.14, 93.72, 92.05, 89.23, 78.4, 62.89, 44.51, 45.93, 43.72, 44.41, 37.83, 42.34, 41.31, 41.4, 41.43, 40.14, 44.71, 42.2, 40.95, 50.14, 40.91, 40.53, 38.48, 32.26, 49.4, 41.93, 33.37, 39.15, 38.0, 39.3, 44.08, 41.13, 38.27, 40.8, 37.88, 36.19, 41.63, 39.24, 36.74, 36.97, 37.69, 40.74, 35.44, 34.47, 43.92, 51.06, 56.45, 68.5, 83.7, 92.03, 92.72, 94.5, 95.41, 93.39, 93.8, 93.43, 93.95, 93.08, 92.45, 90.02, 89.26, 90.7, 91.62, 94.56, 92.62, 94.97, 94.68, 93.04, 94.63, 91.62, 94.98, 94.24, 93.58, 94.14, 92.97, 92.23, 90.15, 90.8, 88.98, 86.73, 88.52, 90.32, 93.9, 94.83, 95.06, 94.32, 94.42, 93.1, 89.18, 88.95, 91.67, 93.05, 94.16, 94.83, 95.12, 93.66, 92.55, 94.71, 93.04, 92.75, 90.57, 86.46, 81.07, 61.82, 53.27, 46.9, 45.13, 42.72, 46.87, 44.26, 37.68, 34.96, 35.5, 39.51, 37.96, 38.6, 41.75, 39.17, 33.57, 39.3, 41.75, 36.43, 47.06, 38.68, 41.32, 48.06, 44.35, 44.21, 57.45, 47.52, 60.86, 53.72, 49.74, 46.48, 41.6, 49.8, 43.59, 48.07, 44.4, 42.35, 50.93, 39.21, 39.47, 41.13, 38.35, 44.19, 41.55, 44.2, 44.14, 45.38, 46.25, 43.57, 53.06, 48.83, 61.01, 57.78, 41.84, 50.29, 49.07, 46.65, 54.11, 47.4, 51.31, 48.46, 53.41, 62.14, 53.46, 62.05, 52.5, 55.14, 56.25, 59.79, 55.59, 49.15, 52.56, 52.67, 45.07, 49.86, 57.35, 44.13, 47.92, 50.16, 41.29, 42.59, 41.44, 44.64, 44.91, 40.42, 45.28, 44.99, 44.11, 46.9, 44.7, 46.32, 42.99, 47.56, 40.35, 38.32, 41.26, 41.25, 41.16, 41.07, 45.18, 36.19, 43.13, 43.05, 40.33, 37.76, 38.28, 35.43, 33.25, 35.71, 37.69, 40.83, 54.37, 67.57, 82.17, 91.91, 94.63, 93.98, 95.76, 96.51, 96.36, 95.33, 96.4, 95.85, 95.86, 94.03, 91.26, 90.86, 91.31, 92.24, 94.76, 93.83, 95.65, 95.65, 95.6, 95.48, 93.53, 95.74, 95.28, 94.89, 95.43, 93.98, 92.48, 91.16, 91.15, 85.83, 83.73, 79.37, 83.53, 87.58, 91.44, 94.17, 95.3, 94.84, 94.79, 95.22, 93.69, 90.13, 90.37, 92.14, 93.97, 94.48, 95.4, 95.7, 94.63, 94.38, 95.83, 95.22, 94.91, 94.59, 93.04, 89.98, 85.01, 74.27, 70.86, 68.85, 62.78, 55.77, 54.93, 55.95, 46.54, 43.44, 42.5, 42.06, 34.43, 40.2, 50.34, 51.99, 53.69, 44.4, 54.82, 41.19, 48.13, 51.15, 49.31, 44.12, 40.48, 44.49, 45.66, 50.33, 51.48, 47.35, 49.29, 46.62, 48.01, 39.48, 51.47, 42.01, 39.0, 45.16, 49.12, 50.72, 44.26, 44.07, 46.24, 45.25, 39.29, 46.68, 42.11, 38.98, 38.78, 44.08, 45.56, 48.28, 43.44, 42.39, 39.34, 43.93, 39.09, 40.79, 38.24, 41.17, 39.21, 43.49, 41.21, 48.69, 44.36, 42.26, 44.94, 43.09, 46.04, 43.55, 44.49, 53.7, 43.63, 46.48, 42.01, 42.36, 54.7, 51.31, 46.8, 55.71, 43.73, 46.0, 38.04, 41.25, 51.88, 44.62, 46.73, 43.63, 39.93, 40.61, 43.82, 53.7, 46.08, 34.74, 44.25, 41.86, 36.71, 43.28, 39.22, 38.0, 44.41, 38.54, 37.05, 41.95, 44.3, 38.36, 39.58, 44.58, 43.77, 40.08, 47.85, 39.31, 45.14, 39.25, 44.23, 41.19, 37.97, 37.63, 37.1, 41.07, 36.18, 40.33, 45.36, 43.81, 41.67, 38.4, 38.14, 44.95, 34.86, 36.59, 36.63, 35.86, 38.39, 35.55, 49.61, 43.0, 46.67, 49.82, 42.52, 44.98, 55.74, 46.13, 48.5, 45.87, 45.6, 46.68, 50.39, 53.95, 55.7, 58.58, 66.11, 69.19, 66.51, 65.14, 63.52, 63.86, 69.37, 65.76, 60.03, 63.65, 51.5, 50.15, 50.66, 52.59, 46.09, 44.21, 45.55, 44.94, 44.23, 42.58, 38.64, 42.76, 45.29, 43.28, 44.05, 38.18, 40.25, 47.1, 38.77, 41.85, 38.63, 39.8, 38.08, 47.39, 36.05, 49.23, 40.39, 40.37, 43.42, 44.81, 46.97, 44.37, 42.3, 38.51, 35.54, 37.31, 36.41, 39.89, 38.06, 38.13, 42.69, 38.33, 40.46, 42.59, 43.07, 42.8, 41.4, 44.17, 43.36, 39.99, 43.55, 40.93, 44.18, 44.73, 44.06, 42.75, 48.66, 39.53, 42.19, 43.45, 38.48, 41.26, 45.5, 53.21, 48.92, 42.06, 46.73, 41.75, 41.44, 43.09, 42.56, 44.22, 41.0, 39.6, 39.5, 41.75, 48.91, 48.06, 49.97, 41.65, 43.86, 39.32, 41.26, 46.04, 48.0, 44.05, 54.0, 41.97, 36.76, 41.35, 40.61, 43.25, 38.5, 45.23, 42.92, 40.31, 45.8, 39.68, 43.49, 41.92, 39.85, 52.77, 38.75, 42.53, 43.74, 38.16, 47.1, 39.85, 40.22, 41.85, 50.01, 43.86, 48.9, 52.59, 53.9, 58.37, 63.45, 67.51, 77.34, 84.65, 89.59, 90.36, 92.32, 93.0, 94.33, 94.87, 94.83, 95.45, 95.81, 97.4, 96.65, 97.24, 97.57, 96.18, 96.81, 97.13, 97.51, 96.61, 96.18, 97.14, 96.63, 97.31, 97.48, 97.51, 97.03, 97.09, 96.83, 97.69, 97.02, 97.45, 97.79, 96.57, 96.61, 97.14, 97.54, 96.99, 97.25, 97.03, 97.75, 97.54, 97.31, 96.66, 97.0, 96.32, 97.38, 95.5, 96.19, 95.56, 96.84, 95.44, 95.94, 95.37, 96.08, 95.6, 94.94, 93.0, 90.79, 88.71, 71.59]
|
[0.75, 0.3, 0.18, 0.0, 0.31, 0.02, 0.33, 0.59, 0.64, 0.11, 0.86, 0.36, 0.81, 0.66, 0.96, 0.56, 0.15, 0.03, 0.52, 0.01, 0.39, 0.55, 0.52, 0.24, 0.55, 0.0, 0.39, 0.38, 0.09, 0.58, 0.5, 0.51, 0.99, 0.7, 0.36, 0.37, 0.12, 0.19, 0.01, 0.26, 0.05, 0.84, 0.65, 0.75, 0.59, 0.08, 0.27, 0.0, 0.13, 0.26, 0.87, 0.29, 0.12, 0.45, 0.41, 0.34, 0.81, 0.57, 0.69, 0.79, 0.77, 0.88, 0.88, 0.91, 0.91, 0.9, 1.0, 0.82, 1.0, 0.99, 1.0, 0.99, 1.0, 0.84, 0.97, 0.88, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.63, 0.72, 0.83, 0.69, 0.63, 0.71, 0.71, 0.91, 0.7, 0.97, 0.93, 0.59, 0.95, 0.87, 0.5, 0.59, 0.62, 0.35, 0.0, 0.39, 0.02, 0.44, 0.62, 0.63, 0.18, 0.89, 0.44, 0.87, 0.56, 0.98, 0.57, 0.13, 0.01, 0.37, 0.01, 0.51, 0.64, 0.44, 0.24, 0.49, 0.0, 0.46, 0.1, 0.45, 0.33, 0.63, 0.64, 0.67, 0.93, 0.28, 0.33, 0.16, 0.27, 0.0, 0.32, 0.07, 0.89, 0.82, 0.58, 0.55, 0.05, 0.24, 0.0, 0.14, 0.16, 0.83, 0.31, 0.15, 0.7, 0.48, 0.4, 0.68, 0.45, 0.87, 0.81, 0.76, 0.98, 1.0, 0.85, 0.92, 0.9, 0.91, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 0.93, 1.0, 0.96, 1.0, 1.0, 1.0, 0.96, 0.98, 0.94, 0.94, 0.96, 0.99, 0.95, 1.0, 1.0, 0.96, 1.0, 0.93, 0.74, 0.69, 0.86, 0.89, 0.81, 0.96, 0.9, 0.9, 0.89, 0.93, 0.94, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.67, 0.92, 0.77, 0.9, 0.91, 0.82, 0.53, 0.42, 0.11, 0.0, 0.43, 0.01, 0.42, 0.66, 0.63, 0.17, 0.77, 0.35, 0.66, 0.49, 0.95, 0.64, 0.15, 0.03, 0.44, 0.01, 0.55, 0.68, 0.46, 0.31, 0.34, 0.0, 0.28, 0.11, 0.41, 0.32, 0.37, 0.63, 0.28, 0.98, 0.63, 0.95, 0.33, 0.29, 0.13, 0.27, 0.0, 0.34, 0.11, 0.95, 0.75, 0.77, 0.62, 0.08, 0.22, 0.0, 0.16, 0.3, 0.79, 0.29, 0.09, 0.69, 0.48, 0.23, 0.71, 0.56, 0.55, 0.45, 0.54, 0.71, 0.61, 0.76, 0.81, 0.71, 0.85, 0.93, 0.92, 0.89, 0.93, 0.87, 0.93, 0.91, 0.87, 0.92, 0.93, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.91, 1.0, 0.93, 1.0, 1.0, 1.0, 1.0, 0.8, 1.0, 1.0, 0.91, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.9, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.81, 0.97, 0.8, 0.98, 1.0, 0.99, 1.0, 0.96, 1.0, 0.93, 0.96, 1.0, 0.89, 1.0, 0.92, 1.0, 0.97, 0.99, 0.96, 0.99, 0.96, 0.99, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.95, 0.98, 0.98, 0.95, 0.95, 0.94, 0.97, 0.91, 1.0, 1.0, 0.94, 1.0, 0.94, 1.0, 0.9, 1.0, 0.74, 1.0, 1.0, 0.84, 1.0, 0.75, 1.0, 1.0, 1.0, 0.93, 1.0, 0.96, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 0.99, 0.99, 0.94, 0.98, 1.0, 0.92, 0.95, 0.86, 0.94, 0.92, 0.97, 0.92, 0.65, 0.97, 0.85, 0.69, 0.79, 0.71, 0.76, 0.67, 0.84, 0.87, 0.9, 0.88, 0.82, 0.71, 0.93, 0.71, 0.69, 0.87, 0.82, 0.9, 0.89, 0.94, 0.94, 0.91, 1.0, 1.0, 1.0, 0.95, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.8, 0.73, 1.0, 0.98, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 1.0, 1.0, 0.96, 1.0, 0.96, 1.0, 0.98, 1.0, 0.93, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.87, 0.79, 0.8, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.98, 1.0, 0.94, 0.97, 0.98, 0.91, 0.99, 0.89, 0.72, 0.74, 0.7, 0.66, 0.6, 0.58, 0.54, 0.42, 0.42, 0.45, 0.57, 0.53, 0.58, 0.45, 0.41, 0.49, 0.63, 0.61, 0.54, 0.69, 0.54, 0.53, 0.56, 0.48, 0.57, 0.56, 0.51, 0.39, 0.48, 0.5, 0.62, 0.63, 0.54, 0.57, 0.75, 0.55, 0.55, 0.54, 0.45, 0.47, 0.5, 0.54, 0.57, 0.43, 0.23, 0.75, 0.51, 0.47, 0.59, 0.73, 0.52, 0.43, 0.6, 0.52, 0.65, 0.45, 0.48, 0.5, 0.55, 0.59, 0.51, 0.67, 0.68, 0.8, 0.84]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 61.798842
| 0.764827
| 1,003
|
O43255
|
Q96KS0
|
15210114
|
UbiNet, UbiBrowser
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
EGLN2
|
MDSPCQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAGSGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRKWAEDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALDYIVPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT
|
Homo sapiens
|
Nucleus
|
Tissue enhanced (testis)
|
{'Ciliated cells': '2.2', 'Basal respiratory cells': '1.7', 'Club cells': '1.9', 'Ionocytes': '1.1', 'Mucus glandular cells': '3.0', 'Serous glandular cells': '0.7', 'Gastric mucus-secreting cells': '10.0', 'Proximal enterocytes': '19.0', 'Paneth cells': '25.3', 'Distal enterocytes': '28.0', 'Intestinal goblet cells': '14.1', 'Exocrine glandular cells': '-0.630', 'Basal prostatic cells': '1.5', 'Prostatic glandular cells': '0.9', 'Breast glandular cells': '0.104', 'Breast myoepithelial cells': '-0.097', 'Glandular and luminal cells': '1.1', 'Secretory cells': '3.0', 'Basal keratinocytes': '3.2', 'Suprabasal keratinocytes': '1.7', 'Basal squamous epithelial cells': '12.6', 'Squamous epithelial cells': '11.4', 'Alveolar cells type 1': '0.364', 'Alveolar cells type 2': '0.036', 'Salivary duct cells': '1.3', 'Ductal cells': '0.622', 'Hepatocytes': '0.382', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.150', 'Distal tubular cells': '6.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.427', 'Sertoli cells': '-0.473', 'Granulosa cells': '2.5', 'Enteroendocrine cells': '26.0', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '-0.539', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.0', 'Bipolar cells': '2.7', 'Horizontal cells': '1.3', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.2', 'Schwann cells': '0.092', 'Spermatogonia': '-0.295', 'Spermatocytes': '0.037', 'Early spermatids': '0.605', 'Late spermatids': '0.638', 'Oocytes': '0.7', 'Cytotrophoblasts': '4.4', 'Syncytiotrophoblasts': '12.9', 'Extravillous trophoblasts': '1.9', 'Endothelial cells': '7.5', 'Lymphatic endothelial cells': '10.3', 'Cardiomyocytes': '0.474', 'Skeletal myocytes': '-0.292', 'Smooth muscle cells': '3.2', 'Adipocytes': '2.9', 'Melanocytes': '-0.133', 'Fibroblasts': '7.0', 'Peritubular cells': '-0.388', 'Endometrial stromal cells': '1.5', 'Ovarian stromal cells': '2.2', 'Undifferentiated cells': '12.4', 'T-cells': '12.1', 'B-cells': '17.0', 'Plasma cells': '5.6', 'Nk-cells': '3.5', 'Granulocytes': '3.2', 'Monocytes': '5.6', 'Macrophages': '7.1', 'Hofbauer cells': '4.8', 'Kupffer cells': '6.6', 'Dendritic cells': '3.4', 'Langerhans cells': '-0.003', 'Erythroid cells': '-0.002', 'Adipocytes (Subcutaneous)': '0.234', 'Adipocytes (Visceral)': '0.039', 'Breast glandular cells (progenitors)': '-0.139', 'Adipocytes (Breast)': '0.288', 'Colon enterocytes': '-0.257', 'Colon enteroendocrine cells': '0.248', 'Enteric glia cells': '0.371', 'Mitotic cells (Colon)': '-0.273', 'Mitotic cells (Heart)': '0.482', 'Podocytes': '-0.071', 'Ascending Loop of Henle cells': '0.399', 'Intercalated cells': '-0.054', 'Cholangiocyte': '0.314', 'NK-cells (Liver)': '-0.279', 'Respiratory ciliated cells': '-0.058', 'Mitotic cells (Lung)': '-0.104', 'NK-cells (Lung)': '0.016', 'B-cells (Lung)': '-0.168', 'Alpha cells': '0.441', 'Beta cells': '0.279', 'Prostate glandular cells': '-0.193', 'Prostate basal glandular cells': '0.037', 'Urothelial cells': '0.082', 'Keratinocyte (other)': '-0.402', 'Keratinocyte (granular)': '-0.384', 'Hair cortex cells': '0.253', 'Inner root sheath cells': '0.227', 'Outer root sheath cells': '0.424', 'Sebaceous gland cells': '0.126', 'Eccrine sweat gland cells': '0.368', 'Adipocytes (Skin)': '0.336', 'Mitotic cells (Skin)': '0.061', 'Parietal cells': '-0.718', 'Chief cells': '-0.599', 'Gastric mucous cells': '-0.392', 'Gastric enteroendocrine cells': '-0.431', 'Mitotic cells (Stomach)': '0.052', 'Parafollicular cells': '0.051', 'Thyroid glandular cells': '0.194', 'Mitotic cells (Thyroid)': '-0.108', 'Adrenal cortex cells': '0.270', 'Adrenal medulla cells': '0.080', 'Mitotic cells (Adrenal gland)': '0.178', 'Minor salivary glandular cells': '0.625', 'Minor salivary gland ductal cells': '0.187', 'Minor salivary gland basal cells': '0.093', 'Mitotic cells (Minor salivary gland)': '0.172', 'Adipocytes (Minor salivary gland)': '0.171', 'Somatotropes': '-0.074', 'Lactotropes': '-0.263', 'Gonadotropes': '-0.060', 'Corticotropes': '-0.263', 'Thyrotropes': '-0.049', 'Undifferentiated cells (Pituitary gland)': '0.481', 'Mitotic cells (Spleen)': '-0.457', 'Platelets': '-0.137', 'Erythrocytes': '-0.079', 'Hematopoietic stem cells': '-0.245', 'B-cells (Spleen)': '0.187', 'NK-cells (Spleen)': '0.291', 'Amygdala excitatory': '0.3', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '0.5', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.5', 'Deep-layer near-projecting': '0.4', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.6', 'Hippocampal ca4': '0.7', 'Hippocampal dentate gyrus': '0.4', 'Lamp5-lhx6 and chandelier': '0.4', 'Lower rhombic lip': '0.7', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.4', 'Mge interneuron': '0.4', 'Midbrain-derived inhibitory': '0.6', 'Miscellaneous': '0.4', 'Splatter': '0.5', 'Thalamic excitatory': '0.3', 'Upper rhombic lip': '1.4', 'Upper-layer intratelencephalic': '0.4', 'Astrocyte': '0.7', 'Bergmann glia': '0.7', 'Central nervous system macrophage': '0.5', 'Choroid plexus epithelial cell': '0.1', 'Committed oligodendrocyte precursor': '0.2', 'Ependymal cell': '0.4', 'Oligodendrocyte': '1.1', 'Oligodendrocyte precursor cell': '0.6', 'Endothelial cell': '1.4', 'Pericyte': '0.8', 'Vascular associated smooth muscle cell': '0.6', 'Fibroblast': '0.5', 'Leukocyte': '1.2', 'Basophil': '153.1', 'Eosinophil': '190.9', 'Neutrophil': '673.6', 'Classical monocyte': '17.5', 'Non-classical monocyte': '20.2', 'Intermediate monocyte': '179.4', 'T-reg': '217.3', 'GdT-cell': '86.0', 'MAIT T-cell': '186.9', 'Memory CD4 T-cell': '102.0', 'Naive CD4 T-cell': '24.9', 'Memory CD8 T-cell': '90.3', 'Naive CD8 T-cell': '30.4', 'Memory B-cell': '85.5', 'Naive B-cell': '27.9', 'Plasmacytoid DC': '126.7', 'Myeloid DC': '159.3', 'NK-cell': '19.7', 'Total PBMC': '195.7', 'Vd2 gdTCR': '166.1', 'Memory CD4 T-cell Th1\\/Th17': '16.8', 'Memory CD4 T-cell Th17': '20.5', 'Memory CD4 T-cell Th2': '21.3', 'Non-Vd2 gdTCR': '141.6', 'Memory CD4 T-cell Th1': '19.9', 'Memory CD4 T-cell TFH': '24.6', 'Terminal effector memory CD4 T-cell': '173.8', 'Central memory CD8 T-cell': '192.0', 'Effector memory CD8 T-cell': '171.5', 'Terminal effector memory CD8 T-cell': '175.6', 'Non-switched memory B-cell': '201.3', 'Plasmablast': '82.1', 'Switched memory B-cell': '241.5', 'Exhausted memory B-cell': '208.6', 'Progenitor cell': '98.7', 'Memory T-reg': '19.9', 'Naive CD4 T-cell activated': '17.3', 'Naive CD8 T-cell activated': '18.8', 'Naive T-reg': '20.8'}
|
5V1B
|
{'Adipose Tissue': 57.519186046511635, 'Adrenal Gland': 47.16658914728682, 'Bladder': 67.36285714285714, 'Blood': 96.49424327233584, 'Blood Vessel': 58.679138576779025, 'Brain': 43.749780847842544, 'Breast': 53.53459694989107, 'Cervix Uteri': 98.20684210526316, 'Colon': 62.12053915275995, 'Esophagus': 50.91386851211072, 'Fallopian Tube': 67.15444444444444, 'Heart': 22.974293844367015, 'Kidney': 32.86797752808989, 'Liver': 22.105924778761064, 'Lung': 96.21524221453286, 'Muscle': 19.13048692403487, 'Nerve': 79.71418416801292, 'Ovary': 79.77216666666666, 'Pancreas': 13.627204268292685, 'Pituitary': 54.61183745583039, 'Prostate': 70.37661224489796, 'Salivary Gland': 38.177839506172845, 'Skin': 37.192979546710895, 'Small Intestine': 49.75497326203209, 'Spleen': 115.64556016597513, 'Stomach': 38.23448467966574, 'Testis': 272.0529916897507, 'Thyroid': 80.0478407350689, 'Uterus': 86.05957746478875, 'Vagina': 73.65961538461538}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[27.45, 30.85, 30.81, 36.25, 43.16, 36.74, 47.93, 47.4, 56.96, 56.14, 44.49, 46.33, 40.93, 37.17, 33.77, 35.71, 31.96, 35.65, 31.52, 30.11, 36.03, 29.82, 38.74, 30.55, 28.52, 32.17, 29.45, 30.64, 28.85, 28.03, 26.36, 27.72, 31.1, 30.15, 35.63, 30.97, 35.43, 34.58, 38.42, 35.06, 33.43, 28.87, 32.21, 28.23, 29.0, 27.18, 25.51, 31.5, 25.98, 32.51, 32.19, 31.47, 37.69, 40.3, 36.19, 36.93, 34.65, 38.57, 35.18, 35.35, 36.2, 36.23, 38.83, 45.84, 35.0, 38.94, 34.23, 39.38, 37.17, 37.05, 38.36, 38.47, 38.01, 33.02, 46.04, 34.41, 35.57, 35.27, 30.69, 36.04, 32.81, 32.39, 35.08, 33.71, 30.11, 30.21, 25.61, 28.58, 27.7, 28.31, 29.08, 28.43, 35.48, 38.94, 39.58, 35.52, 35.88, 38.86, 41.8, 41.37, 35.09, 35.44, 30.86, 35.23, 32.73, 35.49, 38.45, 40.19, 39.09, 35.24, 30.99, 33.42, 31.96, 39.19, 31.69, 31.42, 35.05, 32.42, 34.15, 32.22, 29.14, 33.89, 32.98, 36.35, 31.09, 32.52, 31.32, 32.54, 38.44, 32.29, 39.68, 35.28, 35.19, 36.11, 37.76, 29.26, 36.73, 31.95, 30.92, 33.17, 34.19, 32.58, 33.74, 35.45, 35.72, 34.17, 41.09, 36.75, 33.99, 36.94, 32.46, 36.15, 35.69, 29.44, 43.45, 37.05, 39.36, 44.34, 33.44, 41.5, 41.05, 49.9, 47.29, 42.91, 45.98, 48.87, 51.93, 58.95, 74.61, 82.08, 86.37, 93.42, 93.56, 94.3, 96.03, 95.02, 95.15, 95.25, 94.86, 95.11, 94.97, 94.97, 96.16, 95.12, 94.81, 95.25, 93.04, 90.82, 91.59, 94.85, 96.19, 97.18, 97.99, 97.64, 97.76, 97.31, 98.21, 98.09, 97.62, 97.53, 98.32, 98.34, 98.51, 98.64, 98.65, 98.75, 98.62, 98.52, 98.35, 98.19, 97.71, 97.55, 96.03, 95.06, 95.87, 95.09, 92.89, 92.35, 89.69, 88.51, 83.31, 74.85, 71.66, 65.15, 60.8, 56.59, 50.21, 52.96, 57.85, 59.9, 62.22, 65.97, 67.66, 67.03, 70.35, 80.66, 79.46, 85.94, 91.28, 93.82, 95.27, 95.56, 96.07, 95.22, 93.69, 94.08, 93.79, 94.3, 95.51, 97.14, 97.63, 98.46, 98.38, 98.11, 98.15, 98.45, 98.04, 97.73, 97.89, 97.57, 97.42, 96.49, 95.91, 95.91, 94.69, 95.06, 93.82, 87.88, 89.24, 93.07, 92.51, 88.94, 91.47, 93.31, 94.28, 94.21, 89.11, 92.22, 96.81, 94.8, 96.12, 97.21, 97.47, 97.4, 95.78, 95.42, 93.47, 92.18, 92.07, 91.4, 91.28, 86.8, 85.74, 87.56, 90.67, 93.54, 93.77, 95.46, 95.72, 94.66, 92.28, 91.11, 92.48, 92.38, 95.2, 96.9, 96.8, 97.69, 98.44, 98.51, 98.68, 98.84, 98.78, 98.76, 98.54, 98.07, 97.35, 97.82, 97.1, 96.69, 96.58, 97.39, 97.95, 96.86, 95.81, 96.94, 97.48, 96.85, 97.18, 95.76, 93.78, 90.7, 86.75, 84.04, 86.02, 86.59, 91.87, 93.81, 96.56, 97.11, 98.22, 98.18, 98.56, 98.66, 98.58, 98.7, 98.62, 98.61, 98.28, 98.0, 97.82, 97.55, 96.61, 96.03, 96.24, 96.97, 97.14, 97.17, 95.0, 95.37, 94.63, 93.48, 95.09, 96.47, 96.87, 96.81, 97.89, 98.17, 98.41, 98.53, 98.51, 97.85, 98.22, 97.79, 96.63, 96.25, 94.11, 94.86, 94.94, 92.98, 93.5, 93.52, 90.82, 89.01, 89.23, 86.51, 76.78, 77.58, 72.63, 71.19, 65.52, 53.73, 51.96, 44.77, 41.74, 41.2, 37.71, 41.95, 44.21, 38.85, 47.13, 49.1, 39.45, 53.79, 56.79, 61.52, 62.79]
|
[0.75, 0.68, 0.57, 0.36, 0.42, 0.85, 0.56, 0.2, 0.42, 0.11, 0.74, 0.72, 0.26, 0.8, 0.91, 0.91, 0.94, 0.97, 0.86, 0.98, 0.97, 1.0, 0.99, 0.99, 1.0, 0.97, 0.95, 0.94, 0.95, 0.72, 0.68, 0.54, 0.55, 0.28, 0.14, 0.33, 0.14, 0.28, 0.27, 0.54, 0.85, 0.72, 0.86, 0.94, 0.92, 0.72, 0.91, 0.87, 0.92, 0.95, 0.95, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.97, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.86, 0.76, 0.93, 0.83, 0.87, 0.9, 0.94, 0.85, 0.73, 0.21, 0.43, 0.52, 0.56, 0.25, 0.56, 0.76, 1.0, 0.81, 0.52, 0.95, 0.82, 0.65, 0.89, 0.84, 0.68, 0.84, 0.75, 0.91, 0.89, 0.7, 0.76, 0.84, 0.75, 0.89, 0.92, 0.92, 0.92, 0.95, 0.95, 1.0, 0.97, 0.99, 0.91, 0.94, 0.92, 0.89, 0.91, 0.92, 0.96, 0.83, 0.96, 0.83, 0.98, 1.0, 0.96, 1.0, 0.96, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 0.98, 0.99, 0.93, 1.0, 0.96, 0.94, 0.91, 0.84, 0.76, 0.71, 0.9, 0.89, 0.89, 0.86, 0.81, 0.86, 0.49, 0.42, 0.72, 0.31, 0.3, 0.5, 0.2, 0.0, 0.3, 0.65, 0.24, 0.01, 0.08, 0.46, 0.12, 0.0, 0.65, 0.74, 0.37, 0.06, 0.02, 0.03, 0.19, 0.3, 0.32, 0.63, 0.14, 0.17, 0.42, 0.6, 0.66, 0.15, 0.0, 0.29, 0.51, 0.0, 0.13, 0.43, 0.14, 0.0, 0.31, 0.46, 0.13, 0.29, 0.68, 0.38, 0.69, 0.66, 0.1, 0.66, 0.5, 0.06, 0.5, 0.1, 0.41, 0.32, 0.86, 0.73, 0.93, 0.5, 0.69, 0.37, 0.66, 0.57, 0.06, 0.08, 0.13, 0.03, 0.27, 0.13, 0.14, 0.35, 0.03, 0.24, 0.15, 0.7, 0.34, 0.93, 0.47, 0.02, 0.75, 0.1, 0.0, 0.18, 0.27, 0.03, 0.03, 0.28, 0.43, 0.03, 0.02, 0.18, 0.01, 0.01, 0.47, 0.27, 0.01, 0.57, 0.66, 0.49, 0.02, 0.61, 0.84, 0.24, 0.48, 0.18, 0.5, 0.04, 0.07, 0.08, 0.32, 0.0, 0.09, 0.0, 0.03, 0.0, 0.08, 0.33, 0.21, 0.6, 0.32, 0.33, 0.21, 0.06, 0.49, 0.29, 0.05, 0.05, 0.04, 0.06, 0.12, 0.68, 0.3, 0.06, 0.0, 0.07, 0.02, 0.0, 0.01, 0.02, 0.12, 0.01, 0.01, 0.01, 0.06, 0.57, 0.88, 0.09, 0.35, 0.25, 0.89, 0.73, 0.29, 0.14, 0.0, 0.2, 0.03, 0.16, 0.0, 0.22, 0.08, 0.64, 0.94, 0.41, 0.97, 0.44, 0.41, 0.04, 0.37, 0.05, 0.38, 0.0, 0.29, 0.23, 0.02, 0.13, 0.01, 0.0, 0.03, 0.0, 0.09, 0.01, 0.24, 0.6, 0.31, 0.01, 0.1, 0.06, 0.21, 0.13, 0.4, 0.41, 0.0, 0.59, 0.28, 0.38, 0.03, 0.1, 0.06, 0.04, 0.08, 0.08, 0.07, 0.0, 0.03, 0.06, 0.26, 0.7, 0.3, 0.14, 0.4, 0.39, 0.02, 0.48, 0.48, 0.62, 0.34, 0.66, 0.63, 0.45, 0.6, 0.56, 0.7, 0.86, 0.73, 0.65, 0.91, 0.85, 0.87, 0.86, 0.9, 0.93, 0.93, 0.92, 0.91, 0.95, 0.98]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 67.140811
| 0.535184
| 1,864
|
O43255
|
Q99708
| null |
degron_data
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
RBBP8
|
MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGTSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQNRTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFSMNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASDGNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVLDDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPGADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPYFKGDERETSLQNFPHIEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRFRYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQPYNAIFSPKGKEQKT
|
Homo sapiens
|
Nucleus, Chromosome
|
Low tissue specificity
|
{'Ciliated cells': '31.5', 'Basal respiratory cells': '117.6', 'Club cells': '27.3', 'Ionocytes': '22.5', 'Mucus glandular cells': '29.0', 'Serous glandular cells': '7.6', 'Gastric mucus-secreting cells': '21.8', 'Proximal enterocytes': '17.4', 'Paneth cells': '8.8', 'Distal enterocytes': '10.3', 'Intestinal goblet cells': '10.2', 'Exocrine glandular cells': '-0.705', 'Basal prostatic cells': '44.0', 'Prostatic glandular cells': '6.3', 'Breast glandular cells': '0.541', 'Breast myoepithelial cells': '0.750', 'Glandular and luminal cells': '65.1', 'Secretory cells': '53.2', 'Basal keratinocytes': '31.4', 'Suprabasal keratinocytes': '23.9', 'Basal squamous epithelial cells': '55.6', 'Squamous epithelial cells': '32.2', 'Alveolar cells type 1': '0.242', 'Alveolar cells type 2': '0.228', 'Salivary duct cells': '57.9', 'Ductal cells': '0.674', 'Hepatocytes': '0.293', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.172', 'Distal tubular cells': '30.7', 'Collecting duct cells': '33.1', 'Mesothelial cells': '0.249', 'Sertoli cells': '0.116', 'Granulosa cells': '13.4', 'Enteroendocrine cells': '6.7', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.099', 'Excitatory neurons': '19.7', 'Inhibitory neurons': '14.9', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '5.8', 'Bipolar cells': '5.8', 'Horizontal cells': '1.9', 'Astrocytes': '9.6', 'Oligodendrocyte precursor cells': '9.0', 'Oligodendrocytes': '2.5', 'Microglial cells': '8.1', 'Muller glia cells': '1.7', 'Schwann cells': '0.128', 'Spermatogonia': '0.485', 'Spermatocytes': '0.668', 'Early spermatids': '0.316', 'Late spermatids': '-0.118', 'Oocytes': '44.8', 'Cytotrophoblasts': '13.0', 'Syncytiotrophoblasts': '17.2', 'Extravillous trophoblasts': '9.0', 'Endothelial cells': '15.2', 'Lymphatic endothelial cells': '14.5', 'Cardiomyocytes': '0.355', 'Skeletal myocytes': '-0.203', 'Smooth muscle cells': '15.2', 'Adipocytes': '12.4', 'Melanocytes': '0.285', 'Fibroblasts': '11.9', 'Peritubular cells': '0.114', 'Endometrial stromal cells': '18.4', 'Ovarian stromal cells': '3.2', 'Undifferentiated cells': '22.4', 'T-cells': '12.7', 'B-cells': '17.9', 'Plasma cells': '43.8', 'Nk-cells': '18.1', 'Granulocytes': '73.5', 'Monocytes': '170.0', 'Macrophages': '31.6', 'Hofbauer cells': '12.4', 'Kupffer cells': '9.2', 'Dendritic cells': '50.0', 'Langerhans cells': '0.369', 'Erythroid cells': '-0.015', 'Adipocytes (Subcutaneous)': '-0.140', 'Adipocytes (Visceral)': '-0.234', 'Breast glandular cells (progenitors)': '0.521', 'Adipocytes (Breast)': '-0.587', 'Colon enterocytes': '-0.141', 'Colon enteroendocrine cells': '0.143', 'Enteric glia cells': '0.180', 'Mitotic cells (Colon)': '-0.005', 'Mitotic cells (Heart)': '0.487', 'Podocytes': '0.056', 'Ascending Loop of Henle cells': '0.200', 'Intercalated cells': '-0.049', 'Cholangiocyte': '0.370', 'NK-cells (Liver)': '-0.432', 'Respiratory ciliated cells': '-0.052', 'Mitotic cells (Lung)': '0.092', 'NK-cells (Lung)': '-0.061', 'B-cells (Lung)': '-0.187', 'Alpha cells': '0.388', 'Beta cells': '0.198', 'Prostate glandular cells': '-0.125', 'Prostate basal glandular cells': '0.439', 'Urothelial cells': '0.445', 'Keratinocyte (other)': '0.418', 'Keratinocyte (granular)': '-0.131', 'Hair cortex cells': '-0.122', 'Inner root sheath cells': '-0.040', 'Outer root sheath cells': '0.187', 'Sebaceous gland cells': '0.167', 'Eccrine sweat gland cells': '-0.038', 'Adipocytes (Skin)': '-0.300', 'Mitotic cells (Skin)': '0.493', 'Parietal cells': '-0.301', 'Chief cells': '-0.218', 'Gastric mucous cells': '0.096', 'Gastric enteroendocrine cells': '-0.117', 'Mitotic cells (Stomach)': '0.393', 'Parafollicular cells': '0.125', 'Thyroid glandular cells': '0.414', 'Mitotic cells (Thyroid)': '0.000', 'Adrenal cortex cells': '0.229', 'Adrenal medulla cells': '0.080', 'Mitotic cells (Adrenal gland)': '0.192', 'Minor salivary glandular cells': '0.511', 'Minor salivary gland ductal cells': '0.383', 'Minor salivary gland basal cells': '0.327', 'Mitotic cells (Minor salivary gland)': '0.263', 'Adipocytes (Minor salivary gland)': '0.108', 'Somatotropes': '0.279', 'Lactotropes': '0.066', 'Gonadotropes': '-0.116', 'Corticotropes': '-0.184', 'Thyrotropes': '-0.053', 'Undifferentiated cells (Pituitary gland)': '0.097', 'Mitotic cells (Spleen)': '0.283', 'Platelets': '-0.180', 'Erythrocytes': '0.067', 'Hematopoietic stem cells': '-0.126', 'B-cells (Spleen)': '0.092', 'NK-cells (Spleen)': '0.110', 'Amygdala excitatory': '29.9', 'Cerebellar inhibitory': '22.3', 'Cge interneuron': '13.7', 'Deep-layer corticothalamic and 6b': '32.4', 'Deep-layer intratelencephalic': '30.3', 'Deep-layer near-projecting': '43.2', 'Eccentric medium spiny neuron': '23.0', 'Hippocampal ca1-3': '25.9', 'Hippocampal ca4': '21.8', 'Hippocampal dentate gyrus': '15.6', 'Lamp5-lhx6 and chandelier': '16.6', 'Lower rhombic lip': '28.7', 'Mammillary body': '42.4', 'Medium spiny neuron': '23.6', 'Mge interneuron': '22.2', 'Midbrain-derived inhibitory': '23.8', 'Miscellaneous': '29.7', 'Splatter': '26.6', 'Thalamic excitatory': '22.8', 'Upper rhombic lip': '19.6', 'Upper-layer intratelencephalic': '28.6', 'Astrocyte': '17.7', 'Bergmann glia': '10.1', 'Central nervous system macrophage': '12.7', 'Choroid plexus epithelial cell': '307.9', 'Committed oligodendrocyte precursor': '20.4', 'Ependymal cell': '21.0', 'Oligodendrocyte': '4.9', 'Oligodendrocyte precursor cell': '21.4', 'Endothelial cell': '24.6', 'Pericyte': '13.4', 'Vascular associated smooth muscle cell': '17.3', 'Fibroblast': '20.8', 'Leukocyte': '23.5', 'Basophil': '13.6', 'Eosinophil': '3.9', 'Neutrophil': '4.9', 'Classical monocyte': '16.3', 'Non-classical monocyte': '63.6', 'Intermediate monocyte': '61.6', 'T-reg': '5.6', 'GdT-cell': '1.2', 'MAIT T-cell': '3.7', 'Memory CD4 T-cell': '1.7', 'Naive CD4 T-cell': '1.8', 'Memory CD8 T-cell': '2.1', 'Naive CD8 T-cell': '1.5', 'Memory B-cell': '6.6', 'Naive B-cell': '14.1', 'Plasmacytoid DC': '27.9', 'Myeloid DC': '24.1', 'NK-cell': '3.2', 'Total PBMC': '11.1', 'Vd2 gdTCR': '4.2', 'Memory CD4 T-cell Th1\\/Th17': '2.2', 'Memory CD4 T-cell Th17': '3.3', 'Memory CD4 T-cell Th2': '4.2', 'Non-Vd2 gdTCR': '4.1', 'Memory CD4 T-cell Th1': '2.6', 'Memory CD4 T-cell TFH': '2.1', 'Terminal effector memory CD4 T-cell': '1.1', 'Central memory CD8 T-cell': '5.4', 'Effector memory CD8 T-cell': '9.9', 'Terminal effector memory CD8 T-cell': '4.3', 'Non-switched memory B-cell': '16.2', 'Plasmablast': '43.0', 'Switched memory B-cell': '23.6', 'Exhausted memory B-cell': '17.9', 'Progenitor cell': '27.3', 'Memory T-reg': '6.9', 'Naive CD4 T-cell activated': '70.0', 'Naive CD8 T-cell activated': '47.3', 'Naive T-reg': '1.7'}
|
1Y98, 2L4Z, 4D2H, 7BGF
|
{'Adipose Tissue': 7.913537375415282, 'Adrenal Gland': 5.409236434108528, 'Bladder': 10.710142857142856, 'Blood': 6.7459041334768575, 'Blood Vessel': 7.429841198501872, 'Brain': 3.3327173732021196, 'Breast': 14.623392156862744, 'Cervix Uteri': 14.168368421052632, 'Colon': 7.61190243902439, 'Esophagus': 9.74813564013841, 'Fallopian Tube': 14.684222222222225, 'Heart': 2.2329923344947735, 'Kidney': 20.39412359550562, 'Liver': 3.699601327433629, 'Lung': 12.89461937716263, 'Muscle': 0.9825935242839352, 'Nerve': 7.493332794830371, 'Ovary': 7.319927777777778, 'Pancreas': 4.921371646341464, 'Pituitary': 15.586356890459363, 'Prostate': 9.762032653061224, 'Salivary Gland': 15.190604938271608, 'Skin': 15.168425649530128, 'Small Intestine': 9.209085561497323, 'Spleen': 5.595, 'Stomach': 5.969802228412257, 'Testis': 25.42409972299169, 'Thyroid': 12.633623277182236, 'Uterus': 20.070443661971833, 'Vagina': 16.606698717948717}
|
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0.99, 0.99, 1.0, 0.95, 1.0, 0.98, 1.0, 0.95, 1.0, 0.97, 1.0, 0.9, 1.0, 0.92, 1.0, 0.97, 0.88, 0.96, 0.89, 1.0, 0.98, 1.0, 0.96, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.93, 0.99, 0.95, 1.0, 0.99, 0.99, 0.99, 0.97, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.91, 1.0, 0.87, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.97, 1.0, 0.96, 0.94, 0.87, 0.9, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 0.98, 0.95, 0.99, 0.87, 0.99, 0.8, 1.0, 1.0, 1.0, 1.0, 0.89, 0.99, 0.92, 0.96, 1.0, 0.97, 0.99, 0.98, 1.0, 0.97, 0.99, 0.92, 0.99, 0.9, 0.95, 0.9, 0.94, 0.94, 0.98, 0.94, 0.92, 0.94, 0.83, 0.79, 0.87, 0.75, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.95, 0.98, 0.97, 0.89, 0.94, 0.91, 0.85, 0.94, 0.64, 0.9, 0.82, 0.94, 0.94, 0.92, 0.89, 0.76, 0.91, 0.94, 0.99, 0.99, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.94, 0.99, 0.96, 1.0, 1.0, 0.99, 1.0, 0.98, 0.94, 0.98, 0.8, 0.97, 0.87, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.91, 1.0, 0.97, 1.0, 1.0, 0.97, 1.0, 0.92, 0.99, 0.94, 0.98, 0.95, 0.94, 0.92, 0.95, 0.99, 0.95, 0.88, 0.99, 0.73, 0.94, 1.0, 0.9, 0.76, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.98, 0.89, 0.99, 0.9, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 0.97, 1.0, 0.98, 0.98, 0.98, 0.79, 0.9, 0.84, 0.92, 0.86, 0.94, 0.7, 0.9, 0.75, 0.94, 0.93, 0.77, 0.89, 0.93, 0.92, 0.9, 0.97, 0.94, 0.98, 1.0, 0.96, 1.0, 0.71, 0.96, 0.78, 0.92, 0.84, 0.78, 0.68, 0.89, 0.77, 0.68, 0.74, 0.92, 0.76, 0.43, 0.45, 0.69, 0.75, 0.77, 0.83, 0.8, 0.83, 0.65, 0.72, 0.74, 0.85, 0.89, 0.91, 0.97, 0.97, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.96, 0.99, 0.71, 0.89, 0.67, 0.91, 0.6, 0.87, 0.8, 0.84, 0.55, 0.77, 0.77, 0.83, 0.87, 0.87, 0.93, 0.98, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 0.95, 0.87, 0.78, 0.82, 0.87, 0.44, 0.68, 0.78, 0.51, 0.62, 0.71, 0.8, 0.76, 0.84, 0.79, 0.81, 0.98, 0.79, 0.88, 0.85, 0.81, 0.77, 0.97, 0.9, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.92, 1.0, 0.89, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.99, 0.8, 1.0, 0.63, 0.97, 0.68, 0.97, 0.82, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.81, 0.95, 0.71, 0.93, 0.7, 0.95, 0.77, 0.72, 0.67, 0.62, 0.16, 0.83, 0.63, 0.79, 0.64, 0.35, 0.48, 0.69, 0.78, 0.18, 0.71, 0.25, 0.29, 0.48, 0.25, 0.76, 0.71, 0.17, 0.65, 0.64, 0.84, 0.11, 0.55, 0.91, 0.38, 0.58, 0.58, 0.67, 0.45, 0.3, 0.72, 0.55, 0.44, 0.12, 0.52, 0.66, 0.71, 0.07, 0.91, 0.32, 0.13, 0.45, 0.66, 0.65, 0.65, 0.6, 0.56, 0.93, 0.5, 0.61, 0.93, 0.35, 0.7, 0.79, 0.46, 0.91, 0.58, 0.99, 0.37, 0.4, 0.59, 0.58, 0.24, 0.14, 0.35, 0.65, 0.29, 0.49, 0.61, 0.42, 0.8, 0.66, 0.66, 0.84, 0.81, 0.87, 0.76, 0.85, 0.91, 0.87, 0.92, 0.94, 0.95, 0.93, 0.78, 0.94, 0.78, 0.65, 0.85, 0.85, 0.75, 0.91, 0.9, 0.81, 0.88, 0.91, 0.88, 0.95, 0.97]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 52.780814
| 0.839744
| 652
|
O43255
|
Q99933
|
22199232, UNIPROT
|
UbiNet, UbiBrowser, 31181401
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
BAG1
|
MAQRGGARRPRGDRERLGSRLRALRPGREPRQSEPPAQRGPPPSGRPPARSTASGHDRPTRGAAAGARRPRMKKKTRRRSTRSEELTRSEELTLSEEATWSEEATQSEEATQGEEMNRSQEVTRDEESTRSEEVTREEMAAAGLTVTVTHSNEKHDLHVTSQQGSSEPVVQDLAQVVEEVIGVPQSFQKLIFKGKSLKEMETPLSALGIQDGCRVMLIGKKNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQETERLQSTNFALAE
|
Homo sapiens
|
Nucleus, Cytoplasm, Cytoplasm, Nucleus, Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '107.4', 'Basal respiratory cells': '178.3', 'Club cells': '275.8', 'Ionocytes': '144.7', 'Mucus glandular cells': '167.0', 'Serous glandular cells': '132.7', 'Gastric mucus-secreting cells': '103.2', 'Proximal enterocytes': '239.3', 'Paneth cells': '224.7', 'Distal enterocytes': '193.5', 'Intestinal goblet cells': '239.2', 'Exocrine glandular cells': '-0.703', 'Basal prostatic cells': '111.6', 'Prostatic glandular cells': '103.4', 'Breast glandular cells': '0.300', 'Breast myoepithelial cells': '0.105', 'Glandular and luminal cells': '207.0', 'Secretory cells': '108.7', 'Basal keratinocytes': '306.7', 'Suprabasal keratinocytes': '368.4', 'Basal squamous epithelial cells': '215.6', 'Squamous epithelial cells': '254.5', 'Alveolar cells type 1': '0.359', 'Alveolar cells type 2': '-0.072', 'Salivary duct cells': '207.3', 'Ductal cells': '0.403', 'Hepatocytes': '0.063', 'Cholangiocytes': '145.0', 'Proximal tubular cells': '0.076', 'Distal tubular cells': '310.4', 'Collecting duct cells': '208.1', 'Mesothelial cells': '0.151', 'Sertoli cells': '-0.505', 'Granulosa cells': '66.9', 'Enteroendocrine cells': '209.4', 'Pancreatic endocrine cells': '103.6', 'Leydig cells': '-0.568', 'Excitatory neurons': '5.7', 'Inhibitory neurons': '6.8', 'Cone photoreceptor cells': '266.8', 'Rod photoreceptor cells': '102.5', 'Bipolar cells': '91.5', 'Horizontal cells': '43.4', 'Astrocytes': '5.0', 'Oligodendrocyte precursor cells': '4.2', 'Oligodendrocytes': '9.1', 'Microglial cells': '2.7', 'Muller glia cells': '122.2', 'Schwann cells': '0.100', 'Spermatogonia': '-0.323', 'Spermatocytes': '-0.038', 'Early spermatids': '0.580', 'Late spermatids': '0.807', 'Oocytes': '30.1', 'Cytotrophoblasts': '157.6', 'Syncytiotrophoblasts': '251.7', 'Extravillous trophoblasts': '53.8', 'Endothelial cells': '83.2', 'Lymphatic endothelial cells': '57.9', 'Cardiomyocytes': '0.630', 'Skeletal myocytes': '-0.332', 'Smooth muscle cells': '96.0', 'Adipocytes': '100.0', 'Melanocytes': '0.151', 'Fibroblasts': '70.7', 'Peritubular cells': '-0.421', 'Endometrial stromal cells': '73.6', 'Ovarian stromal cells': '57.7', 'Undifferentiated cells': '163.1', 'T-cells': '69.3', 'B-cells': '62.1', 'Plasma cells': '126.2', 'Nk-cells': '83.8', 'Granulocytes': '93.5', 'Monocytes': '137.9', 'Macrophages': '90.4', 'Hofbauer cells': '100.7', 'Kupffer cells': '76.1', 'Dendritic cells': '168.3', 'Langerhans cells': '0.173', 'Erythroid cells': '-0.039', 'Adipocytes (Subcutaneous)': '0.186', 'Adipocytes (Visceral)': '0.094', 'Breast glandular cells (progenitors)': '0.113', 'Adipocytes (Breast)': '-0.159', 'Colon enterocytes': '-0.191', 'Colon enteroendocrine cells': '0.108', 'Enteric glia cells': '0.033', 'Mitotic cells (Colon)': '-0.238', 'Mitotic cells (Heart)': '0.349', 'Podocytes': '0.010', 'Ascending Loop of Henle cells': '0.465', 'Intercalated cells': '0.085', 'Cholangiocyte': '0.276', 'NK-cells (Liver)': '-0.280', 'Respiratory ciliated cells': '0.016', 'Mitotic cells (Lung)': '-0.187', 'NK-cells (Lung)': '0.086', 'B-cells (Lung)': '-0.170', 'Alpha cells': '0.285', 'Beta cells': '0.082', 'Prostate glandular cells': '0.035', 'Prostate basal glandular cells': '0.527', 'Urothelial cells': '0.555', 'Keratinocyte (other)': '0.533', 'Keratinocyte (granular)': '0.211', 'Hair cortex cells': '-0.228', 'Inner root sheath cells': '-0.216', 'Outer root sheath cells': '-0.174', 'Sebaceous gland cells': '-0.243', 'Eccrine sweat gland cells': '-0.230', 'Adipocytes (Skin)': '-0.447', 'Mitotic cells (Skin)': '0.031', 'Parietal cells': '-0.231', 'Chief cells': '-0.336', 'Gastric mucous cells': '0.024', 'Gastric enteroendocrine cells': '-0.323', 'Mitotic cells (Stomach)': '0.068', 'Parafollicular cells': '0.115', 'Thyroid glandular cells': '0.401', 'Mitotic cells (Thyroid)': '-0.126', 'Adrenal cortex cells': '0.207', 'Adrenal medulla cells': '0.140', 'Mitotic cells (Adrenal gland)': '-0.180', 'Minor salivary glandular cells': '0.482', 'Minor salivary gland ductal cells': '0.050', 'Minor salivary gland basal cells': '0.480', 'Mitotic cells (Minor salivary gland)': '0.369', 'Adipocytes (Minor salivary gland)': '0.163', 'Somatotropes': '0.322', 'Lactotropes': '0.255', 'Gonadotropes': '0.068', 'Corticotropes': '-0.136', 'Thyrotropes': '0.175', 'Undifferentiated cells (Pituitary gland)': '-0.042', 'Mitotic cells (Spleen)': '-0.236', 'Platelets': '-0.043', 'Erythrocytes': '0.098', 'Hematopoietic stem cells': '-0.133', 'B-cells (Spleen)': '0.136', 'NK-cells (Spleen)': '0.141', 'Amygdala excitatory': '7.0', 'Cerebellar inhibitory': '19.7', 'Cge interneuron': '14.0', 'Deep-layer corticothalamic and 6b': '10.4', 'Deep-layer intratelencephalic': '11.7', 'Deep-layer near-projecting': '12.5', 'Eccentric medium spiny neuron': '11.8', 'Hippocampal ca1-3': '7.7', 'Hippocampal ca4': '21.3', 'Hippocampal dentate gyrus': '17.9', 'Lamp5-lhx6 and chandelier': '17.0', 'Lower rhombic lip': '17.0', 'Mammillary body': '15.1', 'Medium spiny neuron': '10.5', 'Mge interneuron': '16.5', 'Midbrain-derived inhibitory': '19.6', 'Miscellaneous': '13.6', 'Splatter': '13.6', 'Thalamic excitatory': '12.5', 'Upper rhombic lip': '19.8', 'Upper-layer intratelencephalic': '10.3', 'Astrocyte': '7.8', 'Bergmann glia': '14.9', 'Central nervous system macrophage': '14.2', 'Choroid plexus epithelial cell': '27.1', 'Committed oligodendrocyte precursor': '15.8', 'Ependymal cell': '9.9', 'Oligodendrocyte': '19.3', 'Oligodendrocyte precursor cell': '9.4', 'Endothelial cell': '19.1', 'Pericyte': '16.1', 'Vascular associated smooth muscle cell': '24.5', 'Fibroblast': '7.4', 'Leukocyte': '19.4', 'Basophil': '47.6', 'Eosinophil': '53.7', 'Neutrophil': '42.7', 'Classical monocyte': '40.9', 'Non-classical monocyte': '42.0', 'Intermediate monocyte': '35.5', 'T-reg': '20.3', 'GdT-cell': '9.6', 'MAIT T-cell': '20.6', 'Memory CD4 T-cell': '10.2', 'Naive CD4 T-cell': '26.2', 'Memory CD8 T-cell': '11.5', 'Naive CD8 T-cell': '24.6', 'Memory B-cell': '11.3', 'Naive B-cell': '31.0', 'Plasmacytoid DC': '46.2', 'Myeloid DC': '46.8', 'NK-cell': '44.5', 'Total PBMC': '30.2', 'Vd2 gdTCR': '16.1', 'Memory CD4 T-cell Th1\\/Th17': '27.7', 'Memory CD4 T-cell Th17': '29.6', 'Memory CD4 T-cell Th2': '30.0', 'Non-Vd2 gdTCR': '20.9', 'Memory CD4 T-cell Th1': '28.3', 'Memory CD4 T-cell TFH': '27.2', 'Terminal effector memory CD4 T-cell': '16.7', 'Central memory CD8 T-cell': '16.8', 'Effector memory CD8 T-cell': '21.4', 'Terminal effector memory CD8 T-cell': '26.1', 'Non-switched memory B-cell': '28.1', 'Plasmablast': '57.2', 'Switched memory B-cell': '30.4', 'Exhausted memory B-cell': '30.6', 'Progenitor cell': '25.3', 'Memory T-reg': '34.0', 'Naive CD4 T-cell activated': '46.9', 'Naive CD8 T-cell activated': '53.5', 'Naive T-reg': '25.7'}
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{'Adipose Tissue': 27.177740863787378, 'Adrenal Gland': 19.84046511627907, 'Bladder': 46.31857142857143, 'Blood': 33.76316469321851, 'Blood Vessel': 31.70116853932584, 'Brain': 21.703347085541257, 'Breast': 28.58235294117647, 'Cervix Uteri': 27.66052631578948, 'Colon': 36.60485237483954, 'Esophagus': 37.55686712802768, 'Fallopian Tube': 24.549999999999997, 'Heart': 25.944216027874567, 'Kidney': 28.701011235955058, 'Liver': 11.777292035398233, 'Lung': 36.88588235294118, 'Muscle': 43.66303860523038, 'Nerve': 34.66219709208401, 'Ovary': 21.58388888888889, 'Pancreas': 13.129420731707317, 'Pituitary': 36.55621908127208, 'Prostate': 38.06126530612245, 'Salivary Gland': 37.03203703703704, 'Skin': 48.48145273631841, 'Small Intestine': 25.28668449197861, 'Spleen': 23.99282157676349, 'Stomach': 29.19818941504178, 'Testis': 70.92149584487535, 'Thyroid': 34.061868300153144, 'Uterus': 23.902535211267605, 'Vagina': 37.44782051282051}
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[45.08, 45.71, 48.5, 48.66, 43.74, 44.6, 48.76, 50.72, 57.13, 57.7, 51.4, 42.38, 40.86, 47.05, 40.53, 47.54, 49.94, 38.72, 42.99, 45.11, 42.07, 45.37, 45.14, 39.36, 52.08, 42.99, 37.25, 45.28, 50.79, 41.82, 44.3, 41.11, 43.78, 49.34, 49.32, 49.4, 50.23, 41.62, 45.06, 58.21, 63.84, 67.83, 49.05, 42.71, 46.11, 44.24, 46.03, 47.56, 44.31, 46.23, 43.31, 49.3, 49.04, 47.78, 47.18, 49.18, 49.76, 52.67, 52.2, 53.49, 47.5, 43.83, 47.44, 48.48, 48.67, 44.28, 52.01, 49.42, 50.29, 52.63, 45.22, 59.01, 48.08, 53.13, 48.53, 46.62, 39.25, 45.04, 39.58, 39.57, 40.0, 37.85, 44.21, 51.28, 38.26, 41.07, 37.97, 33.82, 34.5, 46.05, 33.03, 39.02, 28.03, 35.98, 35.02, 44.1, 33.58, 36.62, 30.14, 35.28, 35.75, 45.4, 36.87, 33.17, 35.67, 36.18, 34.82, 43.69, 36.68, 34.25, 37.2, 32.74, 37.32, 42.5, 34.36, 42.23, 37.94, 34.69, 42.77, 46.52, 36.8, 42.74, 36.93, 35.15, 40.32, 40.38, 35.11, 36.0, 29.83, 29.63, 36.79, 38.43, 29.94, 33.91, 35.1, 39.39, 33.84, 31.92, 37.27, 36.35, 39.28, 53.64, 57.01, 70.15, 74.93, 77.18, 81.39, 79.52, 80.65, 74.36, 67.82, 68.89, 76.06, 79.76, 75.35, 79.28, 76.93, 69.19, 67.46, 58.23, 52.67, 52.25, 44.55, 43.05, 44.61, 53.08, 58.8, 65.01, 74.49, 72.38, 73.76, 76.58, 75.64, 74.41, 77.08, 75.44, 76.17, 74.71, 72.33, 68.19, 69.53, 65.15, 64.42, 66.08, 62.99, 60.32, 62.29, 72.73, 74.52, 76.94, 81.04, 75.36, 73.28, 70.3, 74.6, 71.62, 69.26, 64.64, 58.62, 63.06, 59.61, 68.91, 68.07, 67.67, 65.93, 68.26, 64.58, 69.88, 71.57, 71.3, 73.87, 73.45, 78.06, 78.53, 79.11, 79.12, 74.25, 73.13, 65.17, 61.29, 60.53, 57.52, 58.87, 60.23, 60.23, 64.06, 67.49, 73.8, 73.37, 76.72, 82.38, 83.13, 84.27, 86.22, 89.82, 88.41, 88.71, 92.28, 90.3, 91.79, 92.63, 93.23, 90.94, 90.28, 92.81, 89.64, 88.46, 90.08, 90.27, 87.01, 86.71, 88.53, 85.75, 84.81, 85.64, 86.42, 82.51, 74.9, 79.4, 67.55, 70.99, 73.67, 79.13, 77.73, 76.09, 83.49, 81.84, 81.2, 84.2, 86.58, 84.93, 84.15, 87.55, 89.06, 88.55, 89.91, 90.24, 90.19, 90.54, 92.11, 91.07, 90.78, 92.64, 92.41, 90.6, 91.01, 92.34, 89.49, 89.88, 88.84, 87.77, 85.98, 85.6, 84.81, 75.06, 72.04, 68.79, 67.99, 66.11, 63.52, 68.0, 74.71, 74.78, 75.42, 79.7, 83.4, 83.13, 85.74, 87.7, 89.5, 89.36, 90.69, 92.89, 90.98, 91.73, 92.36, 92.74, 91.2, 91.88, 91.47, 89.23, 89.67, 90.34, 89.18, 85.92, 88.22, 88.37, 85.42, 84.62, 83.3, 83.91, 79.2, 80.66, 81.16, 79.89, 73.55, 71.25, 70.28, 64.82, 60.5, 57.15, 59.01, 58.02, 55.52, 40.8]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.99, 0.98, 0.99, 1.0, 0.98, 0.99, 0.99, 0.99, 1.0, 1.0, 0.85, 0.96, 0.85, 0.85, 0.94, 0.97, 0.92, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.97, 1.0, 1.0, 0.98, 0.95, 0.98, 0.98, 0.89, 0.97, 0.98, 0.95, 0.99, 0.98, 0.99, 1.0, 1.0, 0.97, 1.0, 0.96, 0.99, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.97, 0.99, 0.99, 0.95, 0.99, 0.96, 1.0, 0.94, 0.99, 0.88, 0.98, 0.98, 0.99, 0.99, 1.0, 0.93, 1.0, 0.9, 1.0, 1.0, 1.0, 0.91, 1.0, 0.87, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 0.99, 0.96, 0.91, 1.0, 0.81, 1.0, 1.0, 1.0, 0.95, 0.96, 0.9, 0.99, 1.0, 1.0, 1.0, 0.89, 1.0, 0.91, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 0.97, 0.89, 1.0, 0.92, 0.94, 1.0, 0.98, 0.95, 0.96, 0.98, 0.87, 0.75, 0.63, 0.25, 0.34, 0.01, 0.2, 0.0, 0.16, 0.08, 0.91, 0.97, 0.5, 0.72, 0.24, 0.65, 0.03, 0.64, 0.01, 0.71, 0.34, 0.9, 0.78, 0.98, 0.71, 0.95, 0.51, 0.07, 0.29, 0.05, 0.43, 0.29, 0.0, 0.04, 0.52, 0.22, 0.0, 0.38, 0.74, 0.55, 0.08, 0.44, 0.0, 0.28, 0.33, 0.92, 0.39, 0.1, 0.55, 0.02, 0.24, 0.04, 0.87, 0.81, 0.65, 0.5, 0.07, 0.74, 0.66, 0.41, 0.86, 0.25, 0.23, 0.01, 0.5, 0.71, 0.22, 0.36, 0.07, 0.73, 0.6, 0.61, 0.13, 0.63, 0.0, 0.56, 0.04, 0.5, 0.22, 0.59, 0.41, 0.31, 0.13, 0.45, 0.63, 0.04, 0.31, 0.51, 0.19, 0.13, 0.54, 0.51, 0.02, 0.53, 0.62, 0.05, 0.37, 0.57, 0.38, 0.04, 0.61, 0.65, 0.08, 0.19, 0.5, 0.41, 0.03, 0.49, 0.55, 0.03, 0.31, 0.58, 0.4, 0.08, 0.46, 0.51, 0.11, 0.58, 0.74, 0.55, 0.89, 0.46, 0.59, 0.66, 0.65, 0.5, 0.18, 0.16, 0.51, 0.21, 0.06, 0.37, 0.55, 0.03, 0.14, 0.69, 0.4, 0.01, 0.4, 0.39, 0.03, 0.17, 0.59, 0.37, 0.0, 0.48, 0.59, 0.07, 0.13, 0.6, 0.52, 0.0, 0.71, 0.71, 0.15, 0.82, 0.06, 0.46, 0.77, 0.88, 0.1, 0.75, 0.52, 0.0, 0.39, 0.66, 0.39, 0.26, 0.62, 0.37, 0.04, 0.2, 0.61, 0.6, 0.0, 0.53, 0.44, 0.24, 0.12, 0.48, 0.5, 0.0, 0.41, 0.51, 0.13, 0.2, 0.6, 0.44, 0.01, 0.31, 0.6, 0.35, 0.12, 0.61, 0.61, 0.09, 0.57, 0.6, 0.48, 0.49, 0.7, 0.69, 0.79, 0.8, 0.82]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 63.012087
| 0.635652
| 2,197
|
O43255
|
Q9BQF6
|
31825833
|
UbiBrowser
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
SENP7
|
MDKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLPLQWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRNDANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERIPRVILTNVLGTELGRKYIRTPPVTEGSLSDTDNLQSEQLSSSSDGSLESYQNLNPHKSCYLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESALLELPLITCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASKGCVTITKKYIKIPFQVSLNEISLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQEIQTQLEHSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQAFPLFQNLSSKESSFIHYYCVSTCSFPAGVAVAEEMKLKSVSQPSNTDAAKPTYTFLQKQSSGCYSLSITSNPDEEWREVRHTGLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTIDNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEKWFPRHVIKTKREDIRELILKLHLQQQKGSSS
|
Homo sapiens
|
Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '20.0', 'Basal respiratory cells': '7.0', 'Club cells': '13.2', 'Ionocytes': '9.9', 'Mucus glandular cells': '19.8', 'Serous glandular cells': '13.2', 'Gastric mucus-secreting cells': '17.7', 'Proximal enterocytes': '6.7', 'Paneth cells': '4.1', 'Distal enterocytes': '7.2', 'Intestinal goblet cells': '8.8', 'Exocrine glandular cells': '-0.476', 'Basal prostatic cells': '16.7', 'Prostatic glandular cells': '17.3', 'Breast glandular cells': '0.483', 'Breast myoepithelial cells': '0.508', 'Glandular and luminal cells': '34.8', 'Secretory cells': '18.9', 'Basal keratinocytes': '12.3', 'Suprabasal keratinocytes': '12.7', 'Basal squamous epithelial cells': '16.2', 'Squamous epithelial cells': '12.5', 'Alveolar cells type 1': '0.123', 'Alveolar cells type 2': '-0.189', 'Salivary duct cells': '16.4', 'Ductal cells': '0.461', 'Hepatocytes': '0.198', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.059', 'Distal tubular cells': '12.3', 'Collecting duct cells': '15.6', 'Mesothelial cells': '0.325', 'Sertoli cells': '0.517', 'Granulosa cells': '31.7', 'Enteroendocrine cells': '6.2', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.596', 'Excitatory neurons': '60.3', 'Inhibitory neurons': '104.9', 'Cone photoreceptor cells': '17.0', 'Rod photoreceptor cells': '35.1', 'Bipolar cells': '41.9', 'Horizontal cells': '50.4', 'Astrocytes': '74.3', 'Oligodendrocyte precursor cells': '147.6', 'Oligodendrocytes': '125.0', 'Microglial cells': '76.9', 'Muller glia cells': '16.2', 'Schwann cells': '0.320', 'Spermatogonia': '0.495', 'Spermatocytes': '0.238', 'Early spermatids': '-0.366', 'Late spermatids': '-0.698', 'Oocytes': '8.1', 'Cytotrophoblasts': '5.7', 'Syncytiotrophoblasts': '2.9', 'Extravillous trophoblasts': '3.0', 'Endothelial cells': '28.1', 'Lymphatic endothelial cells': '43.6', 'Cardiomyocytes': '0.517', 'Skeletal myocytes': '0.027', 'Smooth muscle cells': '24.3', 'Adipocytes': '41.6', 'Melanocytes': '0.066', 'Fibroblasts': '22.1', 'Peritubular cells': '0.648', 'Endometrial stromal cells': '45.2', 'Ovarian stromal cells': '36.3', 'Undifferentiated cells': '5.4', 'T-cells': '39.5', 'B-cells': '29.2', 'Plasma cells': '18.5', 'Nk-cells': '37.4', 'Granulocytes': '31.3', 'Monocytes': '26.2', 'Macrophages': '19.4', 'Hofbauer cells': '10.1', 'Kupffer cells': '19.2', 'Dendritic cells': '6.3', 'Langerhans cells': '0.233', 'Erythroid cells': '0.128', 'Adipocytes (Subcutaneous)': '-0.362', 'Adipocytes (Visceral)': '-0.365', 'Breast glandular cells (progenitors)': '0.307', 'Adipocytes (Breast)': '-0.411', 'Colon enterocytes': '-0.138', 'Colon enteroendocrine cells': '0.393', 'Enteric glia cells': '0.423', 'Mitotic cells (Colon)': '-0.097', 'Mitotic cells (Heart)': '0.489', 'Podocytes': '0.011', 'Ascending Loop of Henle cells': '0.507', 'Intercalated cells': '0.080', 'Cholangiocyte': '0.311', 'NK-cells (Liver)': '0.046', 'Respiratory ciliated cells': '0.155', 'Mitotic cells (Lung)': '-0.018', 'NK-cells (Lung)': '0.223', 'B-cells (Lung)': '0.104', 'Alpha cells': '0.380', 'Beta cells': '0.246', 'Prostate glandular cells': '-0.291', 'Prostate basal glandular cells': '-0.019', 'Urothelial cells': '0.016', 'Keratinocyte (other)': '0.040', 'Keratinocyte (granular)': '-0.282', 'Hair cortex cells': '-0.019', 'Inner root sheath cells': '0.003', 'Outer root sheath cells': '0.291', 'Sebaceous gland cells': '0.102', 'Eccrine sweat gland cells': '0.205', 'Adipocytes (Skin)': '0.027', 'Mitotic cells (Skin)': '0.289', 'Parietal cells': '-0.447', 'Chief cells': '-0.509', 'Gastric mucous cells': '-0.381', 'Gastric enteroendocrine cells': '-0.351', 'Mitotic cells (Stomach)': '-0.138', 'Parafollicular cells': '0.105', 'Thyroid glandular cells': '0.354', 'Mitotic cells (Thyroid)': '0.134', 'Adrenal cortex cells': '0.322', 'Adrenal medulla cells': '0.154', 'Mitotic cells (Adrenal gland)': '0.141', 'Minor salivary glandular cells': '0.456', 'Minor salivary gland ductal cells': '0.379', 'Minor salivary gland basal cells': '0.228', 'Mitotic cells (Minor salivary gland)': '0.262', 'Adipocytes (Minor salivary gland)': '0.284', 'Somatotropes': '-0.080', 'Lactotropes': '-0.059', 'Gonadotropes': '0.160', 'Corticotropes': '-0.189', 'Thyrotropes': '0.083', 'Undifferentiated cells (Pituitary gland)': '0.365', 'Mitotic cells (Spleen)': '-0.145', 'Platelets': '-0.016', 'Erythrocytes': '-0.097', 'Hematopoietic stem cells': '-0.229', 'B-cells (Spleen)': '0.323', 'NK-cells (Spleen)': '0.383', 'Amygdala excitatory': '93.7', 'Cerebellar inhibitory': '142.1', 'Cge interneuron': '146.9', 'Deep-layer corticothalamic and 6b': '86.2', 'Deep-layer intratelencephalic': '71.0', 'Deep-layer near-projecting': '116.4', 'Eccentric medium spiny neuron': '147.9', 'Hippocampal ca1-3': '80.2', 'Hippocampal ca4': '69.9', 'Hippocampal dentate gyrus': '103.6', 'Lamp5-lhx6 and chandelier': '145.4', 'Lower rhombic lip': '151.1', 'Mammillary body': '161.0', 'Medium spiny neuron': '98.3', 'Mge interneuron': '148.9', 'Midbrain-derived inhibitory': '148.9', 'Miscellaneous': '110.4', 'Splatter': '145.3', 'Thalamic excitatory': '117.8', 'Upper rhombic lip': '170.7', 'Upper-layer intratelencephalic': '78.2', 'Astrocyte': '145.4', 'Bergmann glia': '197.1', 'Central nervous system macrophage': '208.9', 'Choroid plexus epithelial cell': '125.1', 'Committed oligodendrocyte precursor': '185.2', 'Ependymal cell': '128.7', 'Oligodendrocyte': '215.4', 'Oligodendrocyte precursor cell': '286.7', 'Endothelial cell': '291.2', 'Pericyte': '202.8', 'Vascular associated smooth muscle cell': '145.0', 'Fibroblast': '160.6', 'Leukocyte': '240.6', 'Basophil': '267.7', 'Eosinophil': '5.6', 'Neutrophil': '140.4', 'Classical monocyte': '35.8', 'Non-classical monocyte': '45.9', 'Intermediate monocyte': '54.1', 'T-reg': '82.5', 'GdT-cell': '5.5', 'MAIT T-cell': '66.5', 'Memory CD4 T-cell': '7.5', 'Naive CD4 T-cell': '136.6', 'Memory CD8 T-cell': '5.5', 'Naive CD8 T-cell': '99.6', 'Memory B-cell': '5.9', 'Naive B-cell': '116.6', 'Plasmacytoid DC': '38.3', 'Myeloid DC': '39.3', 'NK-cell': '71.2', 'Total PBMC': '52.6', 'Vd2 gdTCR': '57.9', 'Memory CD4 T-cell Th1\\/Th17': '131.9', 'Memory CD4 T-cell Th17': '89.3', 'Memory CD4 T-cell Th2': '114.2', 'Non-Vd2 gdTCR': '66.3', 'Memory CD4 T-cell Th1': '102.6', 'Memory CD4 T-cell TFH': '81.5', 'Terminal effector memory CD4 T-cell': '73.6', 'Central memory CD8 T-cell': '89.7', 'Effector memory CD8 T-cell': '77.5', 'Terminal effector memory CD8 T-cell': '68.3', 'Non-switched memory B-cell': '81.3', 'Plasmablast': '45.0', 'Switched memory B-cell': '63.5', 'Exhausted memory B-cell': '69.4', 'Progenitor cell': '66.8', 'Memory T-reg': '67.3', 'Naive CD4 T-cell activated': '55.0', 'Naive CD8 T-cell activated': '33.4', 'Naive T-reg': '133.4'}
|
3EAY, 7R2E
|
{'Adipose Tissue': 17.466530813953487, 'Adrenal Gland': 7.34958527131783, 'Bladder': 17.906619047619046, 'Blood': 5.796273832077503, 'Blood Vessel': 20.14882322097378, 'Brain': 8.87379988644966, 'Breast': 19.039333333333335, 'Cervix Uteri': 28.28657894736842, 'Colon': 14.382730423620028, 'Esophagus': 12.493834602076126, 'Fallopian Tube': 27.447777777777777, 'Heart': 5.089873867595819, 'Kidney': 7.539112359550562, 'Liver': 3.338570796460177, 'Lung': 15.22956401384083, 'Muscle': 6.032176836861768, 'Nerve': 32.606504038772215, 'Ovary': 35.30583333333333, 'Pancreas': 6.384661585365853, 'Pituitary': 15.577084805653708, 'Prostate': 13.771555102040816, 'Salivary Gland': 10.099160493827162, 'Skin': 10.814074074074076, 'Small Intestine': 15.66250267379679, 'Spleen': 17.4478755186722, 'Stomach': 12.087387186629527, 'Testis': 11.035227146814403, 'Thyroid': 20.93540275650842, 'Uterus': 33.108943661971836, 'Vagina': 19.200198717948716}
|
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31.3, 28.79, 28.69, 32.15, 33.87, 33.73, 39.73, 43.77, 50.34, 48.48, 45.19, 43.17, 40.19, 38.42, 32.03, 33.79, 32.85, 30.42, 27.44, 31.14, 25.28, 27.63, 29.7, 27.64, 31.94, 28.02, 30.3, 29.62, 30.13, 32.99, 31.31, 31.73, 31.32, 31.46, 25.76, 31.46, 26.54, 33.25, 32.39, 31.46, 26.83, 24.82, 29.12, 27.36, 28.78, 33.35, 27.19, 31.83, 25.55, 28.1, 27.78, 23.81, 28.82, 23.05, 26.83, 26.7, 23.83, 28.04, 23.83, 27.64, 27.44, 25.8, 29.51, 25.85, 26.59, 32.23, 24.46, 30.38, 32.41, 31.01, 29.44, 34.7, 28.33, 35.41, 26.43, 29.73, 32.39, 33.0, 30.68, 27.42, 27.59, 34.61, 44.61, 56.56, 74.5, 85.38, 89.54, 90.51, 89.38, 88.44, 91.44, 89.07, 89.36, 92.11, 90.58, 89.13, 83.45, 82.32, 84.53, 87.62, 88.15, 89.14, 90.3, 87.01, 87.48, 89.11, 91.66, 92.35, 92.59, 90.99, 88.06, 87.63, 91.26, 93.13, 93.26, 93.74, 92.84, 91.81, 88.28, 85.2, 78.92, 77.14, 80.5, 85.81, 86.43, 88.84, 90.75, 91.67, 91.16, 90.11, 89.63, 85.87, 88.2, 89.07, 87.3, 90.12, 91.94, 90.4, 89.36, 87.25, 80.26, 62.77, 56.85, 54.7, 47.92, 43.85, 48.58, 47.59, 51.37, 53.62, 52.28, 68.24, 84.19, 88.74, 91.2, 92.34, 92.53, 91.91, 90.9, 87.84, 83.89, 84.56, 86.05, 82.09, 80.99, 84.74, 84.31, 80.43, 82.86, 82.38, 78.71, 64.77, 57.91, 52.0, 50.65, 52.0, 49.61, 56.4, 57.82, 62.65, 71.08, 71.74, 75.38, 85.24, 90.48, 92.35, 92.45, 92.04, 89.6, 88.67, 81.41, 79.13, 76.54, 80.43, 82.37, 82.03, 83.94, 85.51, 85.22, 85.12, 87.65, 88.61, 87.36, 87.57, 89.33, 89.34, 86.31, 85.79, 87.38, 86.54, 84.46, 82.09, 78.75, 76.13, 72.86, 72.62, 74.56, 80.6, 73.08, 80.37, 85.58, 85.79, 84.2, 80.76, 80.62, 82.54, 82.75, 80.96, 82.69, 81.44, 81.63, 77.15, 74.77, 77.69, 74.71, 73.99, 72.13, 75.08, 81.51, 81.38, 84.42, 81.26, 79.04, 77.61, 71.18, 67.96, 55.63, 46.9, 42.84, 36.0, 29.17, 29.31, 29.59, 31.08, 31.84, 30.23, 28.64, 28.18, 31.87, 33.08, 28.45, 31.38, 33.86, 32.05, 32.49, 27.6, 32.09, 31.01, 35.82, 32.45, 30.17, 30.84, 35.12, 32.99, 37.29, 41.38, 41.47, 40.59, 38.5, 48.28, 45.39, 43.17, 48.01, 55.03, 48.86, 49.63, 44.96, 47.29, 46.18, 35.44, 46.41, 43.14, 45.44, 42.48, 55.45, 50.34, 47.75, 55.84, 54.61, 55.87, 53.21, 49.7, 50.74, 44.86, 41.44, 42.98, 43.99, 50.49, 46.04, 55.57, 73.37, 82.66, 85.38, 89.94, 90.83, 93.51, 93.65, 93.96, 93.09, 90.78, 88.47, 87.21, 85.25, 84.68, 82.75, 87.84, 92.42, 93.29, 94.73, 93.61, 90.91, 90.95, 93.57, 92.74, 90.66, 92.67, 93.59, 90.68, 89.94, 89.67, 92.67, 94.56, 96.19, 94.78, 95.83, 95.87, 97.12, 97.63, 97.0, 96.92, 97.56, 97.22, 95.2, 96.26, 96.28, 93.74, 93.18, 92.93, 91.67, 91.88, 93.13, 92.42, 91.87, 92.16, 93.57, 93.9, 94.85, 95.99, 96.24, 97.11, 97.08, 95.32, 94.61, 94.46, 96.78, 95.62, 93.12, 93.88, 93.04, 91.6, 87.01, 72.3, 64.35, 52.67, 49.57, 48.9, 51.37, 48.0, 55.31, 57.89, 68.38, 78.75, 83.55, 89.74, 89.62, 92.02, 92.54, 91.32, 92.78, 94.74, 92.48, 92.82, 94.29, 92.91, 93.01, 93.02, 93.12, 91.27, 89.44, 92.12, 93.84, 96.0, 96.19, 94.57, 96.09, 95.76, 96.99, 97.78, 98.16, 98.08, 97.9, 96.9, 94.78, 91.02, 87.08, 88.62, 94.77, 96.99, 97.36, 97.92, 97.91, 97.77, 97.74, 96.47, 95.39, 95.33, 93.94, 93.39, 89.43, 89.31, 88.56, 89.69, 85.51, 78.91, 72.36, 58.33, 52.06, 37.09, 31.93, 29.28, 30.92, 35.66, 37.52, 34.04, 37.53, 35.55, 37.57, 37.64, 33.45, 38.02, 31.94, 33.51, 35.7, 37.76, 37.15, 36.37, 42.82, 38.83, 41.93, 39.76, 39.93, 33.77, 37.16, 36.76, 41.77, 39.01, 34.46, 38.67, 39.0, 38.49, 41.63, 39.64, 42.9, 36.32, 38.26, 30.11, 38.5, 33.3, 33.2, 34.55, 37.45, 42.81, 43.72, 58.64, 66.95, 78.98, 85.82, 90.81, 91.97, 95.4, 95.95, 97.53, 96.69, 97.22, 96.52, 96.59, 94.37, 90.47, 86.75, 84.62, 86.29, 89.44, 92.81, 94.35, 94.6, 95.68, 96.84, 96.17, 96.36, 97.28, 97.29, 96.39, 97.0, 97.0, 96.08, 96.08, 96.64, 95.95, 95.29, 94.25, 93.64, 92.76, 91.84, 94.63, 92.03, 93.57, 92.56, 94.79, 93.37, 93.54, 92.22, 90.96, 94.79, 95.41, 95.12, 93.71, 93.79, 93.78, 93.04, 94.14, 95.01, 93.43, 92.1, 87.73, 90.4, 86.85, 91.11, 95.04, 95.79, 96.6, 97.09, 97.71, 97.7, 97.86, 97.63, 97.54, 97.27, 97.0, 96.27, 95.76, 94.25, 92.27, 90.7, 90.63, 88.98, 83.49, 87.19, 89.88, 85.31, 85.46, 85.54, 90.24, 89.14, 91.77, 91.56, 91.76, 93.05, 94.93, 93.15, 89.93, 91.5, 93.99, 94.07, 91.64, 94.55, 96.11, 96.26, 95.21, 96.41, 96.78, 96.08, 95.93, 96.15, 95.59, 93.78, 94.27, 93.78, 93.19, 92.54, 91.37, 89.79, 88.04, 84.38, 74.8, 63.73, 57.82, 40.76]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.95, 1.0, 0.94, 1.0, 0.77, 0.98, 0.76, 1.0, 1.0, 1.0, 0.99, 0.96, 1.0, 0.95, 1.0, 0.94, 0.82, 1.0, 0.99, 0.85, 0.92, 0.99, 0.95, 0.93, 0.97, 1.0, 0.95, 0.97, 0.85, 0.91, 0.86, 0.88, 0.81, 0.94, 0.88, 0.99, 1.0, 0.95, 1.0, 0.9, 1.0, 0.91, 0.99, 0.9, 0.95, 0.93, 0.65, 0.94, 0.66, 0.96, 0.77, 0.9, 0.82, 0.77, 0.88, 0.83, 0.88, 0.82, 0.77, 0.75, 0.76, 0.65, 0.85, 0.79, 0.95, 0.99, 1.0, 1.0, 0.96, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.97, 0.92, 0.82, 0.89, 0.86, 0.84, 0.8, 0.66, 0.79, 0.74, 0.84, 0.57, 0.51, 0.63, 0.51, 0.68, 0.37, 0.65, 0.73, 0.05, 0.55, 0.66, 0.62, 0.63, 0.83, 0.72, 0.67, 0.82, 0.89, 0.89, 0.83, 1.0, 0.87, 1.0, 0.94, 0.94, 0.97, 0.94, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.82, 0.91, 0.99, 0.99, 0.99, 1.0, 0.99, 0.81, 0.96, 0.8, 0.93, 0.76, 0.76, 0.91, 0.83, 0.8, 0.82, 0.75, 0.76, 0.87, 0.72, 0.66, 0.61, 0.58, 0.48, 0.41, 0.78, 0.73, 0.08, 0.55, 0.69, 0.79, 0.62, 0.86, 0.58, 0.79, 0.9, 0.73, 0.88, 0.9, 0.82, 0.99, 0.98, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 1.0, 1.0, 0.98, 0.8, 0.98, 0.8, 1.0, 0.75, 0.97, 0.89, 0.95, 0.98, 0.99, 0.99, 1.0, 1.0, 1.0, 0.93, 0.99, 0.8, 0.9, 0.99, 0.89, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 1.0, 0.97, 1.0, 0.9, 0.99, 0.92, 0.99, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.93, 1.0, 0.92, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 0.97, 0.99, 0.98, 1.0, 0.99, 0.9, 0.89, 0.76, 0.83, 0.84, 0.92, 0.94, 0.96, 0.76, 0.96, 0.89, 0.84, 0.98, 0.93, 0.99, 1.0, 0.93, 1.0, 0.9, 0.99, 1.0, 0.99, 1.0, 0.95, 0.48, 0.63, 0.97, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.76, 0.63, 0.76, 0.52, 0.98, 1.0, 0.99, 1.0, 0.99, 1.0, 0.95, 1.0, 0.79, 1.0, 0.81, 1.0, 0.86, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 0.92, 0.89, 0.88, 0.96, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 0.98, 0.99, 0.98, 1.0, 1.0, 0.96, 1.0, 0.97, 1.0, 1.0, 0.98, 1.0, 0.97, 1.0, 1.0, 1.0, 0.94, 1.0, 0.94, 1.0, 0.98, 0.98, 0.99, 1.0, 1.0, 0.98, 0.98, 0.98, 0.97, 0.89, 0.97, 0.9, 0.83, 0.85, 0.89, 0.82, 0.86, 0.74, 0.53, 0.34, 0.5, 0.07, 0.1, 0.62, 0.54, 0.88, 0.77, 0.84, 0.93, 0.77, 0.73, 0.88, 0.81, 1.0, 1.0, 1.0, 0.97, 1.0, 0.97, 1.0, 0.95, 1.0, 1.0, 1.0, 0.96, 0.97, 1.0, 0.94, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 0.91, 1.0, 0.9, 0.89, 0.88, 0.9, 0.85, 0.92, 0.93, 0.94, 0.96, 0.94, 0.96, 0.98, 0.97, 0.88, 1.0, 0.94, 1.0, 1.0, 0.94, 0.91, 0.88, 0.86, 0.9, 0.97, 0.87, 0.98, 0.99, 0.99, 0.99, 0.95, 1.0, 0.87, 1.0, 0.83, 0.89, 0.53, 0.39, 0.51, 0.05, 0.46, 0.06, 0.6, 0.01, 0.3, 0.12, 0.01, 0.03, 0.04, 0.04, 0.36, 0.12, 0.4, 0.06, 0.51, 0.36, 0.48, 0.45, 0.41, 0.0, 0.14, 0.0, 0.1, 0.22, 0.58, 0.43, 0.02, 0.45, 0.0, 0.15, 0.01, 0.32, 0.21, 0.8, 0.9, 0.44, 0.67, 0.07, 0.58, 0.0, 0.48, 0.04, 0.38, 0.03, 0.58, 0.28, 0.03, 0.26, 0.28, 0.03, 0.0, 0.21, 0.06, 0.25, 0.42, 0.98, 0.8, 0.27, 1.0, 0.68, 0.43, 0.99, 0.48, 0.83, 0.39, 0.03, 0.12, 0.0, 0.0, 0.02, 0.2, 0.01, 0.15, 0.53, 0.67, 0.12, 0.21, 0.48, 0.46, 0.01, 0.19, 0.43, 0.24, 0.1, 0.48, 0.82, 0.08, 0.92, 0.36, 0.99, 0.7, 0.73, 0.2, 0.7, 0.02, 0.22, 0.15, 0.06, 0.01, 0.03, 0.0, 0.11, 0.01, 0.57, 0.66, 0.8, 0.09, 0.43, 0.74, 0.78, 0.33, 0.26, 0.53, 0.42, 0.01, 0.38, 0.47, 0.01, 0.0, 0.38, 0.34, 0.01, 0.08, 0.76, 0.56, 0.33, 0.58, 0.41, 0.72, 0.45, 0.0, 0.39, 0.82, 0.42, 0.06, 0.4, 0.18, 0.72, 0.57, 0.0, 0.27, 0.52, 0.37, 0.0, 0.54, 0.88, 0.19, 0.39, 0.43, 0.69, 0.36, 0.05, 0.07, 0.01, 0.12, 0.56, 0.49, 0.14, 0.07, 0.63, 0.64, 0.64, 0.34, 0.78, 0.68, 0.73, 0.67, 0.83, 0.98, 0.92, 0.99, 0.98, 0.95, 1.0, 0.93, 0.76, 0.92, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.84, 0.94, 0.9, 0.71, 0.75, 0.73, 0.49, 0.59, 0.44, 0.59, 0.52, 0.59, 0.49, 0.9, 0.76, 0.14, 0.25, 0.13, 0.31, 0.19, 0.66, 0.24, 0.81, 0.63, 0.91, 0.95, 0.55, 0.9, 0.57, 0.76, 0.53, 0.37, 0.6, 0.62, 0.81, 0.73, 0.91, 0.48, 0.57, 0.6, 0.14, 0.01, 0.23, 0.04, 0.14, 0.45, 0.8, 0.95, 0.41, 0.7, 0.47, 0.38, 0.24, 0.31, 0.0, 0.22, 0.23, 0.48, 0.1, 0.08, 0.51, 0.1, 0.03, 0.12, 0.84, 0.55, 0.51, 0.49, 0.03, 0.24, 0.21, 0.24, 0.0, 0.0, 0.05, 0.0, 0.07, 0.02, 0.09, 0.12, 0.0, 0.06, 0.48, 0.61, 0.52, 0.21, 0.47, 0.76, 0.66, 0.1, 0.2, 0.75, 0.39, 0.01, 0.02, 0.04, 0.01, 0.09, 0.02, 0.48, 0.0, 0.02, 0.32, 0.31, 0.0, 0.4, 0.69, 0.88, 0.55, 0.88, 0.78, 0.94, 0.76, 0.82, 0.41, 0.61, 0.72, 0.91, 0.32, 0.45, 0.61, 0.14, 0.29, 0.27, 0.24, 0.05, 0.39, 0.26, 0.01, 0.62, 0.54, 0.07, 0.0, 0.67, 1.0, 0.19, 0.31, 0.0, 0.05, 0.71, 0.1, 0.13, 0.04, 0.0, 0.02, 0.01, 0.0, 0.0, 0.29, 0.25, 0.97, 0.48, 0.16, 0.01, 0.0, 0.01, 0.01, 0.0, 0.01, 0.0, 0.03, 0.0, 0.5, 0.14, 0.58, 0.74, 0.45, 0.37, 0.61, 0.36, 0.6, 0.61, 0.68, 0.85, 0.81, 0.67, 0.56, 0.73, 0.8, 0.56, 0.74, 0.69, 0.86, 0.86, 0.83, 0.96, 0.99, 1.0, 1.0, 1.0, 0.98, 0.92, 0.98, 0.88, 1.0, 0.98, 1.0, 1.0, 1.0, 0.88, 0.99, 0.9, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 0.99, 0.9, 0.98, 0.85, 0.81, 0.89, 0.82, 0.88, 0.82, 0.7, 0.77, 0.56, 0.13, 0.01, 0.21, 0.18, 0.01, 0.0, 0.0, 0.0, 0.04, 0.02, 0.05, 0.0, 0.44, 0.93, 0.23, 0.96, 0.24, 0.14, 0.52, 0.46, 0.0, 0.0, 0.45, 0.04, 0.01, 0.04, 0.16, 0.02, 0.0, 0.25, 0.08, 0.01, 0.12, 0.48, 0.6, 0.33, 0.43, 0.83, 0.53, 0.8, 0.1, 0.65, 0.02, 0.25, 0.55, 0.85, 0.3, 0.0, 0.26, 0.23, 0.06, 0.68, 0.07, 0.39, 0.05, 0.13, 0.46, 0.11, 0.76, 0.38, 0.71, 0.06, 0.11, 0.02, 0.0, 0.01, 0.04, 0.01, 0.0, 0.06, 0.01, 0.0, 0.23, 0.09, 0.01, 0.05, 0.87, 0.63, 0.27, 0.07, 0.49, 0.35, 0.0, 0.58, 0.61, 0.59, 0.07, 0.59, 0.13, 0.49, 0.93, 0.17, 0.1, 0.53, 0.74, 0.67, 0.24, 0.06, 0.79, 0.38, 0.03, 0.07, 0.52, 0.35, 0.0, 0.16, 0.43, 0.14, 0.0, 0.37, 0.61, 0.12, 0.16, 0.62, 0.54, 0.22, 0.46, 0.72, 0.6, 0.81, 0.76, 0.81]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 55.984762
| 0.663305
| 460
|
O43255
|
Q9BSI4
|
22064479
|
UbiNet, UbiBrowser, 31181401
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
TINF2
|
MATPLVAGPAALRFAAAASWQVVRGRCVEHFPRVLEFLRSLRAVAPGLVRYRHHERLCMGLKAKVVVELILQGRPWAQVLKALNHHFPESGPIVRDPKATKQDLRKILEAQETFYQQVKQLSEAPVDLASKLQELEQEYGEPFLAAMEKLLFEYLCQLEKALPTPQAQQLQDVLSWMQPGVSITSSLAWRQYGVDMGWLLPECSVTDSVNLAEPMEQNPPQQQRLALHNPLPKAKPGTHLPQGPSSRTHPEPLAGRHFNLAPLGRRRVQSQWASTRGGHKERPTVMLFPFRNLGSPTQVISKPESKEEHAIYTADLAMGTRAASTGKSKSPCQTLGGRALKENPVDLPATEQKENCLDCYMDPLRLSLLPPRARKPVCPPSLCSSVITIGDLVLDSDEEENGQGEGKESLENYQKTKFDTLIPTLCEYLPPSGHGAIPVSSCDCRDSSRPL
|
Homo sapiens
|
Nucleus, Chromosome, telomere, Nucleus matrix
|
Tissue enriched (parathyroid)
|
{'Ciliated cells': '16.2', 'Basal respiratory cells': '32.8', 'Club cells': '25.6', 'Ionocytes': '28.7', 'Mucus glandular cells': '13.2', 'Serous glandular cells': '13.8', 'Gastric mucus-secreting cells': '15.9', 'Proximal enterocytes': '23.5', 'Paneth cells': '23.1', 'Distal enterocytes': '20.2', 'Intestinal goblet cells': '18.5', 'Exocrine glandular cells': '-0.789', 'Basal prostatic cells': '25.3', 'Prostatic glandular cells': '17.3', 'Breast glandular cells': '0.203', 'Breast myoepithelial cells': '0.117', 'Glandular and luminal cells': '18.9', 'Secretory cells': '35.5', 'Basal keratinocytes': '18.8', 'Suprabasal keratinocytes': '29.5', 'Basal squamous epithelial cells': '23.3', 'Squamous epithelial cells': '28.5', 'Alveolar cells type 1': '0.143', 'Alveolar cells type 2': '0.000', 'Salivary duct cells': '13.1', 'Ductal cells': '0.577', 'Hepatocytes': '0.429', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.137', 'Distal tubular cells': '15.4', 'Collecting duct cells': '15.6', 'Mesothelial cells': '0.294', 'Sertoli cells': '0.378', 'Granulosa cells': '19.8', 'Enteroendocrine cells': '17.6', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.553', 'Excitatory neurons': '3.9', 'Inhibitory neurons': '3.9', 'Cone photoreceptor cells': '25.5', 'Rod photoreceptor cells': '16.3', 'Bipolar cells': '26.4', 'Horizontal cells': '11.3', 'Astrocytes': '5.9', 'Oligodendrocyte precursor cells': '3.3', 'Oligodendrocytes': '6.9', 'Microglial cells': '7.2', 'Muller glia cells': '41.0', 'Schwann cells': '-0.075', 'Spermatogonia': '0.446', 'Spermatocytes': '0.344', 'Early spermatids': '-0.287', 'Late spermatids': '-0.545', 'Oocytes': '27.9', 'Cytotrophoblasts': '31.9', 'Syncytiotrophoblasts': '45.0', 'Extravillous trophoblasts': '28.5', 'Endothelial cells': '33.2', 'Lymphatic endothelial cells': '23.4', 'Cardiomyocytes': '0.488', 'Skeletal myocytes': '-0.347', 'Smooth muscle cells': '30.2', 'Adipocytes': '32.0', 'Melanocytes': '0.098', 'Fibroblasts': '24.9', 'Peritubular cells': '0.459', 'Endometrial stromal cells': '15.6', 'Ovarian stromal cells': '28.8', 'Undifferentiated cells': '16.2', 'T-cells': '42.9', 'B-cells': '44.5', 'Plasma cells': '32.1', 'Nk-cells': '57.9', 'Granulocytes': '56.4', 'Monocytes': '35.3', 'Macrophages': '28.7', 'Hofbauer cells': '36.9', 'Kupffer cells': '27.8', 'Dendritic cells': '34.1', 'Langerhans cells': '0.327', 'Erythroid cells': '-0.020', 'Adipocytes (Subcutaneous)': '-0.123', 'Adipocytes (Visceral)': '-0.097', 'Breast glandular cells (progenitors)': '0.095', 'Adipocytes (Breast)': '-0.087', 'Colon enterocytes': '-0.159', 'Colon enteroendocrine cells': '0.247', 'Enteric glia cells': '-0.223', 'Mitotic cells (Colon)': '-0.062', 'Mitotic cells (Heart)': '0.519', 'Podocytes': '-0.077', 'Ascending Loop of Henle cells': '0.336', 'Intercalated cells': '-0.109', 'Cholangiocyte': '0.399', 'NK-cells (Liver)': '-0.315', 'Respiratory ciliated cells': '-0.075', 'Mitotic cells (Lung)': '-0.054', 'NK-cells (Lung)': '0.115', 'B-cells (Lung)': '-0.119', 'Alpha cells': '0.323', 'Beta cells': '0.128', 'Prostate glandular cells': '-0.175', 'Prostate basal glandular cells': '0.145', 'Urothelial cells': '0.121', 'Keratinocyte (other)': '0.334', 'Keratinocyte (granular)': '0.134', 'Hair cortex cells': '-0.152', 'Inner root sheath cells': '-0.105', 'Outer root sheath cells': '-0.053', 'Sebaceous gland cells': '-0.162', 'Eccrine sweat gland cells': '-0.224', 'Adipocytes (Skin)': '-0.194', 'Mitotic cells (Skin)': '0.070', 'Parietal cells': '-0.689', 'Chief cells': '-0.492', 'Gastric mucous cells': '-0.428', 'Gastric enteroendocrine cells': '-0.404', 'Mitotic cells (Stomach)': '0.025', 'Parafollicular cells': '0.101', 'Thyroid glandular cells': '0.291', 'Mitotic cells (Thyroid)': '-0.029', 'Adrenal cortex cells': '0.510', 'Adrenal medulla cells': '-0.039', 'Mitotic cells (Adrenal gland)': '0.143', 'Minor salivary glandular cells': '0.346', 'Minor salivary gland ductal cells': '-0.223', 'Minor salivary gland basal cells': '0.669', 'Mitotic cells (Minor salivary gland)': '0.681', 'Adipocytes (Minor salivary gland)': '0.306', 'Somatotropes': '-0.065', 'Lactotropes': '-0.219', 'Gonadotropes': '-0.169', 'Corticotropes': '-0.122', 'Thyrotropes': '-0.001', 'Undifferentiated cells (Pituitary gland)': '0.254', 'Mitotic cells (Spleen)': '-0.313', 'Platelets': '-0.020', 'Erythrocytes': '-0.218', 'Hematopoietic stem cells': '-0.185', 'B-cells (Spleen)': '0.401', 'NK-cells (Spleen)': '0.312', 'Amygdala excitatory': '4.2', 'Cerebellar inhibitory': '5.8', 'Cge interneuron': '7.1', 'Deep-layer corticothalamic and 6b': '5.6', 'Deep-layer intratelencephalic': '4.6', 'Deep-layer near-projecting': '4.8', 'Eccentric medium spiny neuron': '4.2', 'Hippocampal ca1-3': '3.9', 'Hippocampal ca4': '4.0', 'Hippocampal dentate gyrus': '4.7', 'Lamp5-lhx6 and chandelier': '5.9', 'Lower rhombic lip': '8.1', 'Mammillary body': '4.1', 'Medium spiny neuron': '4.2', 'Mge interneuron': '5.1', 'Midbrain-derived inhibitory': '5.3', 'Miscellaneous': '4.6', 'Splatter': '5.4', 'Thalamic excitatory': '5.4', 'Upper rhombic lip': '7.8', 'Upper-layer intratelencephalic': '4.4', 'Astrocyte': '5.7', 'Bergmann glia': '9.3', 'Central nervous system macrophage': '7.6', 'Choroid plexus epithelial cell': '4.8', 'Committed oligodendrocyte precursor': '6.4', 'Ependymal cell': '4.5', 'Oligodendrocyte': '10.3', 'Oligodendrocyte precursor cell': '7.2', 'Endothelial cell': '12.9', 'Pericyte': '18.1', 'Vascular associated smooth muscle cell': '14.2', 'Fibroblast': '8.8', 'Leukocyte': '15.7', 'Basophil': '155.8', 'Eosinophil': '109.2', 'Neutrophil': '140.0', 'Classical monocyte': '88.0', 'Non-classical monocyte': '89.8', 'Intermediate monocyte': '89.1', 'T-reg': '82.1', 'GdT-cell': '56.5', 'MAIT T-cell': '104.9', 'Memory CD4 T-cell': '44.8', 'Naive CD4 T-cell': '92.0', 'Memory CD8 T-cell': '53.4', 'Naive CD8 T-cell': '87.3', 'Memory B-cell': '57.0', 'Naive B-cell': '163.2', 'Plasmacytoid DC': '106.9', 'Myeloid DC': '87.1', 'NK-cell': '183.2', 'Total PBMC': '88.9', 'Vd2 gdTCR': '106.9', 'Memory CD4 T-cell Th1\\/Th17': '90.8', 'Memory CD4 T-cell Th17': '99.1', 'Memory CD4 T-cell Th2': '108.2', 'Non-Vd2 gdTCR': '115.5', 'Memory CD4 T-cell Th1': '112.4', 'Memory CD4 T-cell TFH': '117.3', 'Terminal effector memory CD4 T-cell': '108.8', 'Central memory CD8 T-cell': '57.4', 'Effector memory CD8 T-cell': '99.0', 'Terminal effector memory CD8 T-cell': '102.2', 'Non-switched memory B-cell': '97.9', 'Plasmablast': '111.3', 'Switched memory B-cell': '96.7', 'Exhausted memory B-cell': '80.1', 'Progenitor cell': '48.8', 'Memory T-reg': '136.4', 'Naive CD4 T-cell activated': '128.0', 'Naive CD8 T-cell activated': '134.7', 'Naive T-reg': '96.7'}
|
3BQO, 3BU8, 5XYF
|
{'Adipose Tissue': 73.01824750830565, 'Adrenal Gland': 87.2463565891473, 'Bladder': 70.88666666666666, 'Blood': 69.28100753498386, 'Blood Vessel': 81.27608988764045, 'Brain': 28.18199659348978, 'Breast': 71.40074074074074, 'Cervix Uteri': 81.41105263157894, 'Colon': 56.63655969191271, 'Esophagus': 70.92424221453287, 'Fallopian Tube': 73.46555555555555, 'Heart': 21.738234610917537, 'Kidney': 38.58719101123596, 'Liver': 18.315862831858407, 'Lung': 81.37190311418685, 'Muscle': 31.59970112079701, 'Nerve': 85.59256865912764, 'Ovary': 60.199, 'Pancreas': 23.984670731707315, 'Pituitary': 52.42816254416961, 'Prostate': 64.5465306122449, 'Salivary Gland': 50.96320987654322, 'Skin': 56.8555002763958, 'Small Intestine': 56.40930481283423, 'Spleen': 81.63141078838173, 'Stomach': 47.07434540389972, 'Testis': 33.209972299168975, 'Thyroid': 78.5669372128637, 'Uterus': 87.34767605633803, 'Vagina': 72.02807692307692}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[40.16, 39.69, 48.86, 51.42, 57.28, 62.93, 70.09, 82.79, 86.62, 87.79, 90.13, 92.49, 93.2, 92.34, 94.51, 95.25, 94.74, 95.52, 97.39, 97.06, 96.4, 97.44, 96.68, 94.7, 95.43, 96.75, 96.49, 96.34, 94.94, 97.15, 97.53, 96.97, 96.94, 97.98, 97.18, 96.65, 96.68, 96.48, 94.32, 93.78, 93.47, 92.24, 90.81, 88.88, 88.53, 89.21, 87.27, 90.52, 91.32, 90.1, 90.08, 88.2, 91.58, 93.07, 91.11, 89.8, 93.9, 94.89, 91.79, 92.98, 96.1, 95.55, 92.96, 95.17, 96.29, 95.15, 94.11, 96.27, 96.35, 95.33, 93.96, 95.25, 93.74, 95.66, 95.19, 95.53, 95.2, 96.15, 95.91, 95.07, 95.47, 94.89, 94.07, 94.08, 93.3, 91.1, 90.0, 86.44, 70.39, 59.85, 58.7, 54.74, 56.18, 60.25, 59.19, 65.7, 67.9, 70.47, 79.02, 84.81, 85.12, 85.02, 84.78, 86.46, 84.95, 84.38, 83.66, 87.02, 87.11, 84.7, 86.46, 87.12, 88.09, 88.8, 90.36, 90.6, 90.26, 90.61, 91.71, 91.48, 92.29, 92.29, 92.58, 80.56, 81.73, 84.37, 89.08, 90.91, 91.02, 91.56, 90.24, 91.97, 91.77, 89.12, 87.23, 89.98, 87.99, 84.81, 89.41, 88.01, 91.29, 88.38, 88.34, 90.9, 90.3, 88.13, 91.94, 93.53, 92.9, 92.73, 96.08, 94.06, 93.23, 95.12, 94.97, 93.02, 93.07, 93.25, 91.83, 90.95, 89.83, 90.17, 90.37, 88.22, 85.6, 82.25, 78.27, 79.41, 81.08, 80.4, 81.13, 83.15, 83.61, 82.32, 83.73, 82.53, 80.71, 81.64, 80.33, 76.26, 80.53, 78.11, 75.58, 79.29, 79.23, 84.79, 87.86, 89.45, 90.03, 89.43, 90.02, 92.81, 91.13, 90.82, 90.8, 90.88, 88.69, 87.76, 78.0, 61.47, 56.73, 44.1, 36.78, 31.4, 35.49, 33.16, 34.93, 35.45, 39.47, 34.47, 39.57, 40.22, 34.74, 41.12, 39.69, 36.97, 37.92, 37.24, 40.48, 39.38, 36.64, 33.13, 36.68, 25.83, 38.25, 30.73, 37.25, 39.11, 38.12, 40.51, 37.95, 43.26, 33.87, 36.34, 39.06, 40.83, 35.4, 32.8, 37.91, 37.47, 37.95, 33.44, 34.01, 32.89, 36.15, 31.77, 34.5, 30.92, 34.89, 44.0, 42.27, 44.18, 47.69, 39.28, 45.62, 41.34, 50.49, 44.32, 43.8, 42.57, 38.23, 35.52, 33.28, 31.71, 31.2, 31.2, 32.36, 30.63, 33.49, 33.95, 36.16, 30.37, 35.71, 31.42, 39.6, 37.9, 35.65, 31.11, 39.04, 32.45, 34.46, 29.71, 38.61, 28.79, 31.85, 27.73, 31.21, 31.55, 31.64, 30.01, 39.26, 29.45, 37.81, 34.34, 37.52, 39.92, 36.32, 40.36, 38.47, 39.58, 41.59, 42.1, 44.69, 39.54, 39.88, 41.73, 37.92, 37.29, 38.09, 37.37, 37.38, 35.07, 36.49, 38.8, 37.7, 40.95, 35.22, 39.72, 42.54, 42.54, 40.47, 39.79, 39.87, 43.85, 40.66, 40.83, 39.33, 40.24, 38.98, 32.89, 40.32, 32.97, 35.87, 31.23, 37.54, 35.65, 34.22, 37.45, 31.63, 42.74, 36.01, 42.66, 31.09, 45.66, 45.33, 35.91, 36.68, 37.51, 28.76, 37.85, 31.27, 31.96, 30.63, 33.94, 34.26, 27.87, 30.78, 31.22, 30.1, 32.32, 34.69, 29.21, 31.83, 33.25, 31.25, 28.08, 30.01, 29.3, 31.14, 35.48, 37.06, 36.54, 31.36, 36.93, 34.53, 31.37, 32.65, 29.27, 36.95, 35.69, 33.17, 32.95, 28.36, 37.21, 45.34, 47.8, 53.05, 42.77, 41.74, 36.79, 48.01, 40.86, 39.74, 45.09, 45.55, 38.52, 44.1, 44.73, 41.09, 35.97, 35.42, 34.61, 35.77, 32.12, 30.67, 38.1, 33.82, 43.47, 43.56, 49.06, 53.71, 53.4, 56.11, 53.86, 63.21, 65.01, 66.15, 58.99, 44.5, 46.5, 43.92, 46.02, 49.05, 53.11, 53.72, 53.73, 49.53, 49.04, 48.63, 44.24, 46.4, 47.43, 34.48, 40.64, 32.28, 36.94, 38.86, 40.55, 35.55, 37.83, 39.73, 34.11, 39.84, 36.04, 41.53, 39.64, 42.09, 49.62, 47.06, 41.67, 44.73]
|
[0.98, 0.96, 0.85, 0.69, 0.91, 0.38, 0.79, 0.28, 0.24, 0.11, 0.26, 0.3, 0.01, 0.19, 0.32, 0.0, 0.05, 0.52, 0.06, 0.03, 0.4, 0.12, 0.01, 0.33, 0.51, 0.28, 0.26, 0.1, 0.8, 0.53, 0.0, 0.39, 0.55, 0.02, 0.08, 0.38, 0.11, 0.0, 0.61, 0.56, 0.06, 0.13, 0.78, 0.5, 0.08, 0.39, 0.54, 0.1, 0.13, 0.55, 0.04, 0.3, 0.15, 0.07, 0.16, 0.16, 0.0, 0.07, 0.04, 0.01, 0.0, 0.21, 0.0, 0.08, 0.13, 0.0, 0.0, 0.28, 0.17, 0.08, 0.38, 0.54, 0.73, 0.43, 0.58, 0.26, 0.73, 0.44, 0.01, 0.33, 0.72, 0.15, 0.0, 0.41, 0.83, 0.16, 0.05, 0.52, 0.72, 0.93, 0.51, 0.82, 0.74, 0.46, 0.87, 0.16, 0.78, 0.52, 0.28, 0.48, 0.63, 0.33, 0.14, 0.28, 0.6, 0.42, 0.06, 0.55, 0.64, 0.07, 0.23, 0.52, 0.37, 0.0, 0.13, 0.37, 0.24, 0.0, 0.42, 0.55, 0.04, 0.21, 0.66, 0.72, 0.27, 0.98, 0.43, 0.22, 0.74, 0.52, 0.35, 0.23, 0.69, 0.61, 0.01, 0.57, 0.67, 0.16, 0.0, 0.18, 0.53, 0.6, 0.07, 0.06, 0.43, 0.13, 0.0, 0.16, 0.15, 0.04, 0.0, 0.0, 0.07, 0.01, 0.0, 0.06, 0.24, 0.0, 0.13, 0.53, 0.24, 0.11, 0.59, 0.79, 0.38, 0.49, 0.36, 0.55, 0.23, 0.15, 0.49, 0.49, 0.21, 0.29, 0.48, 0.66, 0.71, 0.58, 0.74, 0.98, 0.59, 0.93, 0.3, 0.87, 0.46, 0.34, 0.69, 0.22, 0.09, 0.44, 0.34, 0.0, 0.01, 0.61, 0.2, 0.07, 0.65, 0.13, 0.92, 0.39, 0.78, 0.89, 0.83, 0.71, 0.75, 0.7, 0.76, 0.69, 0.87, 0.9, 0.91, 0.89, 0.93, 0.91, 0.96, 0.96, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.75, 1.0, 0.91, 0.99, 0.95, 0.9, 0.96, 0.92, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.89, 1.0, 0.91, 0.95, 0.99, 0.88, 0.99, 0.89, 0.93, 0.93, 0.88, 0.81, 0.83, 0.51, 0.4, 0.29, 0.77, 0.51, 0.06, 0.62, 0.12, 0.68, 0.9, 0.35, 0.66, 0.95, 0.89, 0.89, 0.91, 0.87, 0.93, 0.95, 0.96, 0.87, 0.92, 0.9, 0.99, 0.97, 1.0, 1.0, 1.0, 0.95, 0.93, 0.86, 0.78, 0.88, 0.74, 0.96, 0.85, 0.98, 1.0, 0.97, 0.99, 0.97, 0.95, 0.99, 0.99, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.96, 1.0, 0.94, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.81, 0.92, 0.79, 0.8, 0.73, 0.85, 0.78, 0.69, 0.83, 0.81, 0.9, 0.88, 0.77, 0.85, 0.86, 0.92, 0.94, 0.95, 0.97, 0.96, 0.96, 0.93, 0.91, 0.92, 0.92, 0.95, 0.92, 0.9, 0.82, 0.71, 0.69, 0.69, 0.2, 0.46, 0.45, 0.88, 0.38, 0.23, 0.46, 0.64, 0.32, 0.69, 0.68, 0.87, 0.74, 0.94, 0.93, 0.97, 0.76, 0.99, 0.97, 0.89, 0.99, 0.61, 0.51, 0.6, 0.79, 0.36, 0.37, 0.66, 0.6, 0.33, 0.98, 0.85, 0.62, 0.55, 0.45, 0.4, 0.39, 0.27, 0.14, 0.71, 0.79, 0.48, 0.38, 0.76, 0.91, 0.83, 0.87, 0.9, 0.97, 0.87, 0.86, 0.92, 0.84, 0.99, 0.99, 0.99, 0.98, 0.97, 0.99, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 60.151175
| 0.631463
| 1,764
|
O43255
|
Q9GZT9
|
19546213, E3Net
|
UbiNet, UbiBrowser, 31181401
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
EGLN1
|
MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPPAAVPPPRAGAREPRKAAARRDNASGDAAKGKVKAKPPADPAAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPSDSVGKDVF
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Tissue enhanced (skeletal)
|
{'Ciliated cells': '2.7', 'Basal respiratory cells': '1.0', 'Club cells': '2.2', 'Ionocytes': '1.5', 'Mucus glandular cells': '3.0', 'Serous glandular cells': '4.6', 'Gastric mucus-secreting cells': '11.8', 'Proximal enterocytes': '18.3', 'Paneth cells': '11.0', 'Distal enterocytes': '24.3', 'Intestinal goblet cells': '11.9', 'Exocrine glandular cells': '-0.521', 'Basal prostatic cells': '6.0', 'Prostatic glandular cells': '3.6', 'Breast glandular cells': '0.245', 'Breast myoepithelial cells': '0.293', 'Glandular and luminal cells': '3.1', 'Secretory cells': '5.1', 'Basal keratinocytes': '6.6', 'Suprabasal keratinocytes': '9.0', 'Basal squamous epithelial cells': '17.7', 'Squamous epithelial cells': '14.3', 'Alveolar cells type 1': '0.134', 'Alveolar cells type 2': '-0.262', 'Salivary duct cells': '4.5', 'Ductal cells': '0.478', 'Hepatocytes': '0.319', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.234', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.311', 'Sertoli cells': '0.655', 'Granulosa cells': '8.3', 'Enteroendocrine cells': '13.3', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.682', 'Excitatory neurons': '42.4', 'Inhibitory neurons': '50.4', 'Cone photoreceptor cells': '8.5', 'Rod photoreceptor cells': '22.6', 'Bipolar cells': '7.8', 'Horizontal cells': '8.8', 'Astrocytes': '34.7', 'Oligodendrocyte precursor cells': '43.4', 'Oligodendrocytes': '44.9', 'Microglial cells': '42.0', 'Muller glia cells': '5.9', 'Schwann cells': '0.056', 'Spermatogonia': '0.556', 'Spermatocytes': '0.158', 'Early spermatids': '-0.485', 'Late spermatids': '-0.734', 'Oocytes': '4.4', 'Cytotrophoblasts': '2.6', 'Syncytiotrophoblasts': '1.5', 'Extravillous trophoblasts': '5.5', 'Endothelial cells': '15.7', 'Lymphatic endothelial cells': '14.9', 'Cardiomyocytes': '0.601', 'Skeletal myocytes': '-0.438', 'Smooth muscle cells': '9.3', 'Adipocytes': '11.6', 'Melanocytes': '0.111', 'Fibroblasts': '7.4', 'Peritubular cells': '0.553', 'Endometrial stromal cells': '4.2', 'Ovarian stromal cells': '6.2', 'Undifferentiated cells': '10.1', 'T-cells': '9.0', 'B-cells': '10.9', 'Plasma cells': '14.9', 'Nk-cells': '6.5', 'Granulocytes': '16.8', 'Monocytes': '6.7', 'Macrophages': '8.6', 'Hofbauer cells': '2.3', 'Kupffer cells': '5.9', 'Dendritic cells': '0.8', 'Langerhans cells': '0.296', 'Erythroid cells': '0.025', 'Adipocytes (Subcutaneous)': '-0.426', 'Adipocytes (Visceral)': '-0.441', 'Breast glandular cells (progenitors)': '0.016', 'Adipocytes (Breast)': '-0.359', 'Colon enterocytes': '-0.227', 'Colon enteroendocrine cells': '0.234', 'Enteric glia cells': '0.218', 'Mitotic cells (Colon)': '-0.144', 'Mitotic cells (Heart)': '0.414', 'Podocytes': '0.071', 'Ascending Loop of Henle cells': '0.294', 'Intercalated cells': '0.022', 'Cholangiocyte': '0.362', 'NK-cells (Liver)': '-0.367', 'Respiratory ciliated cells': '-0.005', 'Mitotic cells (Lung)': '-0.119', 'NK-cells (Lung)': '0.077', 'B-cells (Lung)': '0.009', 'Alpha cells': '0.336', 'Beta cells': '0.147', 'Prostate glandular cells': '-0.425', 'Prostate basal glandular cells': '-0.208', 'Urothelial cells': '-0.077', 'Keratinocyte (other)': '0.359', 'Keratinocyte (granular)': '-0.032', 'Hair cortex cells': '-0.250', 'Inner root sheath cells': '-0.188', 'Outer root sheath cells': '-0.062', 'Sebaceous gland cells': '-0.060', 'Eccrine sweat gland cells': '-0.114', 'Adipocytes (Skin)': '-0.179', 'Mitotic cells (Skin)': '0.245', 'Parietal cells': '-0.661', 'Chief cells': '-0.479', 'Gastric mucous cells': '-0.571', 'Gastric enteroendocrine cells': '-0.392', 'Mitotic cells (Stomach)': '-0.140', 'Parafollicular cells': '0.056', 'Thyroid glandular cells': '0.361', 'Mitotic cells (Thyroid)': '0.042', 'Adrenal cortex cells': '0.404', 'Adrenal medulla cells': '-0.029', 'Mitotic cells (Adrenal gland)': '0.188', 'Minor salivary glandular cells': '0.127', 'Minor salivary gland ductal cells': '-0.014', 'Minor salivary gland basal cells': '0.361', 'Mitotic cells (Minor salivary gland)': '0.315', 'Adipocytes (Minor salivary gland)': '0.321', 'Somatotropes': '0.035', 'Lactotropes': '-0.090', 'Gonadotropes': '-0.162', 'Corticotropes': '0.047', 'Thyrotropes': '0.069', 'Undifferentiated cells (Pituitary gland)': '0.167', 'Mitotic cells (Spleen)': '-0.222', 'Platelets': '-0.196', 'Erythrocytes': '-0.059', 'Hematopoietic stem cells': '-0.172', 'B-cells (Spleen)': '0.162', 'NK-cells (Spleen)': '0.299', 'Amygdala excitatory': '69.3', 'Cerebellar inhibitory': '73.7', 'Cge interneuron': '74.6', 'Deep-layer corticothalamic and 6b': '70.0', 'Deep-layer intratelencephalic': '61.8', 'Deep-layer near-projecting': '66.7', 'Eccentric medium spiny neuron': '74.9', 'Hippocampal ca1-3': '75.9', 'Hippocampal ca4': '56.2', 'Hippocampal dentate gyrus': '71.3', 'Lamp5-lhx6 and chandelier': '75.9', 'Lower rhombic lip': '58.0', 'Mammillary body': '68.3', 'Medium spiny neuron': '76.0', 'Mge interneuron': '70.0', 'Midbrain-derived inhibitory': '76.9', 'Miscellaneous': '62.0', 'Splatter': '62.0', 'Thalamic excitatory': '61.1', 'Upper rhombic lip': '75.9', 'Upper-layer intratelencephalic': '61.2', 'Astrocyte': '67.0', 'Bergmann glia': '80.5', 'Central nervous system macrophage': '119.8', 'Choroid plexus epithelial cell': '70.7', 'Committed oligodendrocyte precursor': '52.8', 'Ependymal cell': '48.0', 'Oligodendrocyte': '76.6', 'Oligodendrocyte precursor cell': '85.0', 'Endothelial cell': '161.7', 'Pericyte': '131.7', 'Vascular associated smooth muscle cell': '86.7', 'Fibroblast': '63.0', 'Leukocyte': '77.9', 'Basophil': '31.7', 'Eosinophil': '3.2', 'Neutrophil': '309.3', 'Classical monocyte': '19.3', 'Non-classical monocyte': '49.1', 'Intermediate monocyte': '20.0', 'T-reg': '11.0', 'GdT-cell': '1.2', 'MAIT T-cell': '17.7', 'Memory CD4 T-cell': '0.9', 'Naive CD4 T-cell': '26.4', 'Memory CD8 T-cell': '0.8', 'Naive CD8 T-cell': '23.2', 'Memory B-cell': '0.7', 'Naive B-cell': '25.6', 'Plasmacytoid DC': '9.4', 'Myeloid DC': '16.7', 'NK-cell': '29.0', 'Total PBMC': '16.3', 'Vd2 gdTCR': '14.3', 'Memory CD4 T-cell TFH': '23.1', 'Memory CD4 T-cell Th2': '27.5', 'Memory CD4 T-cell Th17': '25.5', 'Memory CD4 T-cell Th1\\/Th17': '34.6', 'Non-Vd2 gdTCR': '17.5', 'Memory CD4 T-cell Th1': '24.7', 'Terminal effector memory CD4 T-cell': '17.9', 'Central memory CD8 T-cell': '11.9', 'Effector memory CD8 T-cell': '13.8', 'Terminal effector memory CD8 T-cell': '14.7', 'Switched memory B-cell': '13.8', 'Plasmablast': '13.2', 'Non-switched memory B-cell': '13.2', 'Exhausted memory B-cell': '14.7', 'Progenitor cell': '6.8', 'Naive CD4 T-cell activated': '18.9', 'Naive CD8 T-cell activated': '20.8', 'Memory T-reg': '22.3', 'Naive T-reg': '32.2'}
|
2G19, 2G1M, 2HBT, 2HBU, 2Y33, 2Y34, 3HQR, 3HQU, 3OUH, 3OUI, 3OUJ, 4BQW, 4BQX, 4BQY, 4JZR, 4KBZ, 4UWD, 5A3U, 5L9B, 5L9R, 5L9V, 5LA9, 5LAS, 5LAT, 5LB6, 5LBB, 5LBC, 5LBE, 5LBF, 5OX5, 5OX6, 5V18, 6NMQ, 6QGV, 6ST3, 6YVT, 6YVW, 6YVX, 6YVZ, 6YW0, 6YW1, 6YW2, 6YW3, 6YW4, 6ZBN, 6ZBO, 7Q5V, 7Q5X, 7UJV, 7UMP, 8J1K
|
{'Adipose Tissue': 37.97436627906977, 'Adrenal Gland': 21.261612403100777, 'Bladder': 25.85761904761905, 'Blood': 22.130175995694294, 'Blood Vessel': 32.18263670411985, 'Brain': 20.140864118092356, 'Breast': 33.04213507625273, 'Cervix Uteri': 30.447894736842105, 'Colon': 26.699458279845956, 'Esophagus': 23.908940484429067, 'Fallopian Tube': 30.172222222222224, 'Heart': 20.410591173054588, 'Kidney': 14.282123595505617, 'Liver': 15.266300884955752, 'Lung': 15.968070934256057, 'Muscle': 175.59474470734745, 'Nerve': 37.23505654281099, 'Ovary': 30.82761111111111, 'Pancreas': 12.10234756097561, 'Pituitary': 20.5970777385159, 'Prostate': 18.014926530612247, 'Salivary Gland': 17.816, 'Skin': 30.00324599226092, 'Small Intestine': 18.35653475935829, 'Spleen': 17.641360995850622, 'Stomach': 14.79851810584958, 'Testis': 15.04034349030471, 'Thyroid': 20.189318529862177, 'Uterus': 31.066197183098588, 'Vagina': 28.405576923076925}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[35.08, 32.98, 34.19, 30.47, 39.44, 29.1, 35.0, 44.74, 36.52, 42.29, 48.63, 46.04, 53.21, 56.64, 54.58, 54.05, 55.3, 62.52, 80.62, 85.55, 89.1, 87.15, 84.78, 86.86, 81.9, 81.8, 83.06, 83.23, 86.26, 88.34, 89.52, 92.17, 91.33, 88.19, 86.91, 89.78, 89.87, 86.92, 88.54, 93.15, 92.81, 90.94, 92.17, 92.94, 93.93, 93.04, 93.09, 92.7, 89.65, 90.17, 90.48, 89.32, 87.08, 90.35, 90.65, 87.47, 86.14, 88.07, 83.0, 68.0, 54.31, 47.92, 39.41, 35.51, 42.19, 34.97, 41.72, 35.38, 38.82, 33.74, 40.08, 42.67, 38.78, 42.5, 39.34, 39.88, 50.42, 38.77, 46.95, 57.62, 42.75, 37.52, 45.56, 55.36, 53.99, 56.7, 38.92, 40.6, 39.73, 38.53, 42.68, 38.05, 48.7, 43.63, 44.3, 40.65, 42.28, 41.42, 39.62, 42.04, 42.16, 38.77, 40.97, 38.33, 38.28, 39.85, 40.62, 39.59, 39.99, 35.86, 37.61, 40.15, 35.29, 37.03, 36.67, 44.92, 41.39, 38.87, 35.3, 40.8, 36.95, 34.19, 35.63, 34.68, 40.86, 37.13, 35.14, 36.48, 34.56, 37.57, 37.05, 35.33, 33.98, 34.6, 34.93, 36.87, 31.39, 34.93, 32.23, 35.57, 31.76, 35.26, 37.9, 33.19, 35.71, 31.91, 33.89, 33.92, 35.37, 36.88, 34.43, 29.62, 32.51, 27.09, 33.06, 27.23, 30.92, 31.26, 33.81, 32.4, 35.11, 41.46, 35.56, 29.91, 32.86, 32.55, 32.28, 35.33, 32.21, 32.91, 34.38, 32.27, 37.22, 34.94, 41.17, 31.24, 32.25, 29.25, 29.69, 37.09, 31.67, 31.45, 32.44, 35.91, 49.32, 57.95, 65.8, 76.47, 89.93, 90.69, 93.64, 94.92, 96.14, 96.62, 96.44, 97.26, 97.66, 97.98, 98.24, 97.97, 97.73, 98.14, 97.33, 95.73, 95.15, 96.95, 97.93, 98.5, 98.64, 98.32, 98.09, 97.27, 98.13, 97.62, 96.85, 97.38, 98.02, 98.26, 98.4, 98.51, 98.59, 98.76, 98.48, 98.54, 98.55, 98.55, 98.26, 98.11, 97.53, 96.57, 96.74, 96.23, 93.99, 94.24, 94.0, 91.13, 87.72, 78.22, 75.15, 67.84, 63.68, 59.75, 56.71, 54.88, 55.71, 55.77, 62.83, 68.47, 66.83, 72.24, 75.51, 85.37, 86.04, 91.61, 94.62, 96.44, 97.61, 97.65, 97.81, 97.01, 94.99, 96.0, 95.41, 96.29, 96.52, 97.67, 98.19, 98.35, 98.59, 98.36, 98.38, 98.61, 98.42, 98.04, 97.94, 98.23, 97.78, 97.2, 97.52, 97.37, 96.65, 96.3, 96.12, 92.35, 93.72, 96.93, 96.83, 94.67, 95.33, 96.91, 96.6, 96.92, 93.44, 94.59, 98.19, 97.09, 97.77, 98.17, 98.23, 98.21, 97.96, 97.92, 97.05, 95.57, 94.7, 94.02, 94.7, 94.24, 94.28, 94.57, 93.57, 94.54, 94.61, 95.63, 96.4, 94.98, 91.98, 90.08, 91.99, 92.65, 96.04, 97.82, 97.92, 98.54, 98.74, 98.76, 98.84, 98.91, 98.88, 98.77, 98.67, 97.68, 97.26, 98.11, 97.68, 97.48, 97.14, 97.55, 98.04, 98.03, 97.85, 98.61, 98.64, 98.23, 98.23, 97.12, 94.69, 90.35, 86.05, 84.85, 84.06, 86.05, 93.69, 95.98, 97.97, 98.41, 98.46, 98.7, 98.71, 98.75, 98.64, 98.8, 98.78, 98.83, 98.77, 98.66, 98.48, 98.11, 96.93, 95.05, 96.63, 97.47, 97.29, 98.11, 97.54, 98.11, 97.64, 97.12, 97.82, 97.76, 97.73, 98.09, 98.46, 98.7, 98.75, 98.76, 98.77, 98.55, 98.62, 98.5, 97.91, 97.79, 95.35, 95.74, 95.22, 93.23, 93.3, 93.73, 90.25, 87.22, 87.7, 81.43, 72.07, 73.15, 69.29, 53.05, 46.6, 43.26, 32.71, 36.51, 30.71, 37.17, 29.82, 31.3, 29.44, 29.8, 31.64, 34.04, 32.47, 34.6, 36.47, 35.12, 35.11, 36.96, 45.45, 43.36]
|
[1.0, 1.0, 0.99, 0.94, 0.96, 0.85, 0.86, 0.96, 0.94, 0.89, 0.41, 0.39, 0.66, 0.4, 0.51, 0.57, 0.39, 0.65, 0.16, 0.24, 0.0, 0.28, 0.37, 0.24, 0.15, 0.57, 0.32, 0.82, 0.79, 0.22, 0.46, 0.58, 0.01, 0.79, 0.66, 0.1, 0.67, 0.6, 0.12, 0.11, 0.0, 0.21, 0.35, 0.66, 0.47, 0.22, 0.25, 0.7, 0.52, 0.09, 0.42, 0.77, 0.69, 0.04, 0.58, 0.85, 0.69, 0.12, 0.81, 0.53, 0.74, 0.93, 0.89, 0.97, 0.96, 1.0, 1.0, 1.0, 0.96, 0.94, 0.96, 0.99, 1.0, 0.98, 1.0, 0.97, 1.0, 0.99, 0.99, 0.98, 0.98, 0.96, 0.99, 0.93, 0.98, 0.98, 0.99, 1.0, 0.98, 1.0, 0.99, 0.98, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.99, 0.96, 1.0, 1.0, 0.99, 0.99, 1.0, 1.0, 0.99, 1.0, 0.97, 0.99, 0.99, 0.98, 0.97, 0.95, 0.99, 0.97, 0.99, 0.92, 0.95, 0.98, 0.99, 0.99, 0.99, 0.97, 0.99, 1.0, 0.98, 1.0, 0.95, 1.0, 0.98, 0.94, 0.95, 0.58, 0.61, 0.55, 0.44, 0.89, 0.8, 0.82, 0.92, 0.99, 1.0, 0.96, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.88, 0.89, 0.91, 0.93, 0.92, 0.86, 0.92, 0.86, 0.94, 0.9, 0.82, 0.61, 0.66, 0.26, 0.5, 0.43, 0.13, 0.0, 0.39, 0.65, 0.4, 0.01, 0.12, 0.46, 0.09, 0.0, 0.5, 0.87, 0.49, 0.05, 0.05, 0.0, 0.13, 0.08, 0.52, 0.78, 0.15, 0.27, 0.37, 0.74, 0.75, 0.2, 0.0, 0.34, 0.43, 0.0, 0.03, 0.44, 0.12, 0.0, 0.32, 0.45, 0.11, 0.26, 0.82, 0.63, 0.64, 0.59, 0.13, 0.61, 0.49, 0.04, 0.57, 0.24, 0.65, 0.46, 0.69, 0.67, 0.54, 0.97, 0.36, 0.17, 0.65, 0.69, 0.19, 0.09, 0.23, 0.03, 0.36, 0.07, 0.15, 0.49, 0.05, 0.4, 0.27, 0.8, 0.32, 0.89, 0.4, 0.01, 0.64, 0.14, 0.0, 0.11, 0.49, 0.0, 0.01, 0.49, 0.23, 0.0, 0.21, 0.3, 0.02, 0.05, 0.64, 0.26, 0.01, 0.35, 0.71, 0.42, 0.03, 0.58, 0.88, 0.18, 0.55, 0.11, 0.68, 0.4, 0.33, 0.22, 0.45, 0.0, 0.09, 0.0, 0.03, 0.0, 0.07, 0.33, 0.01, 0.82, 0.36, 0.21, 0.2, 0.18, 0.55, 0.11, 0.22, 0.2, 0.13, 0.04, 0.42, 0.71, 0.31, 0.18, 0.01, 0.13, 0.03, 0.01, 0.01, 0.0, 0.11, 0.0, 0.01, 0.06, 0.05, 0.43, 0.96, 0.12, 0.43, 0.16, 0.91, 0.73, 0.18, 0.15, 0.0, 0.17, 0.02, 0.22, 0.0, 0.15, 0.06, 0.61, 0.97, 0.37, 0.98, 0.41, 0.41, 0.11, 0.39, 0.03, 0.32, 0.0, 0.31, 0.23, 0.0, 0.12, 0.0, 0.0, 0.01, 0.0, 0.05, 0.01, 0.25, 0.33, 0.35, 0.01, 0.09, 0.06, 0.22, 0.11, 0.23, 0.46, 0.0, 0.63, 0.33, 0.44, 0.02, 0.13, 0.05, 0.0, 0.08, 0.0, 0.09, 0.03, 0.13, 0.06, 0.24, 0.44, 0.23, 0.3, 0.47, 0.56, 0.03, 0.58, 0.57, 0.54, 0.57, 0.84, 0.54, 0.57, 0.74, 0.96, 0.87, 0.54, 0.93, 0.47, 0.86, 0.86, 0.78, 0.88, 0.8, 0.87, 0.86, 0.91, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 71.737911
| 0.548521
| 1,864
|
O43255
|
Q9H6Z9
|
16958618, E3NethUbiquitome
|
UbiNet, UbiBrowser, 31181401
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
EGLN3
|
MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED
|
Homo sapiens
|
Nucleus, Cytoplasm
|
Tissue enhanced (heart muscle, skin)
|
{'Ciliated cells': '32.2', 'Basal respiratory cells': '53.2', 'Club cells': '44.5', 'Ionocytes': '25.0', 'Mucus glandular cells': '11.5', 'Serous glandular cells': '13.7', 'Gastric mucus-secreting cells': '78.4', 'Proximal enterocytes': '56.5', 'Paneth cells': '37.3', 'Distal enterocytes': '68.5', 'Intestinal goblet cells': '38.6', 'Exocrine glandular cells': '-0.573', 'Basal prostatic cells': '40.7', 'Prostatic glandular cells': '4.4', 'Breast glandular cells': '0.357', 'Breast myoepithelial cells': '0.350', 'Glandular and luminal cells': '17.8', 'Secretory cells': '6.1', 'Basal keratinocytes': '121.1', 'Suprabasal keratinocytes': '127.0', 'Basal squamous epithelial cells': '2.4', 'Squamous epithelial cells': '4.1', 'Alveolar cells type 1': '0.055', 'Alveolar cells type 2': '-0.442', 'Salivary duct cells': '11.5', 'Ductal cells': '0.484', 'Hepatocytes': '0.056', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.140', 'Distal tubular cells': '21.5', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.270', 'Sertoli cells': '0.040', 'Granulosa cells': '3.5', 'Enteroendocrine cells': '18.1', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.185', 'Excitatory neurons': '0.9', 'Inhibitory neurons': '4.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '2.0', 'Bipolar cells': '9.8', 'Horizontal cells': '11.3', 'Astrocytes': '34.4', 'Oligodendrocyte precursor cells': '6.1', 'Oligodendrocytes': '50.4', 'Microglial cells': '0.0', 'Muller glia cells': '11.9', 'Schwann cells': '0.267', 'Spermatogonia': '0.086', 'Spermatocytes': '-0.150', 'Early spermatids': '-0.104', 'Late spermatids': '-0.176', 'Oocytes': '2.9', 'Cytotrophoblasts': '12.2', 'Syncytiotrophoblasts': '90.7', 'Extravillous trophoblasts': '132.0', 'Endothelial cells': '23.5', 'Lymphatic endothelial cells': '27.8', 'Cardiomyocytes': '0.585', 'Skeletal myocytes': '0.170', 'Smooth muscle cells': '10.3', 'Adipocytes': '7.5', 'Melanocytes': '0.002', 'Fibroblasts': '23.4', 'Peritubular cells': '0.162', 'Endometrial stromal cells': '8.4', 'Ovarian stromal cells': '1.2', 'Undifferentiated cells': '12.0', 'T-cells': '5.4', 'B-cells': '12.6', 'Plasma cells': '0.2', 'Nk-cells': '0.4', 'Granulocytes': '0.7', 'Monocytes': '0.7', 'Macrophages': '8.0', 'Hofbauer cells': '2.4', 'Kupffer cells': '2.3', 'Dendritic cells': '332.0', 'Langerhans cells': '0.148', 'Erythroid cells': '0.135', 'Adipocytes (Subcutaneous)': '-0.478', 'Adipocytes (Visceral)': '-0.481', 'Breast glandular cells (progenitors)': '0.057', 'Adipocytes (Breast)': '-0.538', 'Colon enterocytes': '-0.027', 'Colon enteroendocrine cells': '0.055', 'Enteric glia cells': '0.151', 'Mitotic cells (Colon)': '0.047', 'Mitotic cells (Heart)': '0.459', 'Podocytes': '-0.241', 'Ascending Loop of Henle cells': '0.314', 'Intercalated cells': '-0.274', 'Cholangiocyte': '0.388', 'NK-cells (Liver)': '-0.180', 'Respiratory ciliated cells': '0.098', 'Mitotic cells (Lung)': '-0.174', 'NK-cells (Lung)': '0.232', 'B-cells (Lung)': '0.218', 'Alpha cells': '0.297', 'Beta cells': '0.065', 'Prostate glandular cells': '-0.488', 'Prostate basal glandular cells': '-0.137', 'Urothelial cells': '0.096', 'Keratinocyte (other)': '0.504', 'Keratinocyte (granular)': '0.251', 'Hair cortex cells': '-0.358', 'Inner root sheath cells': '-0.378', 'Outer root sheath cells': '-0.361', 'Sebaceous gland cells': '-0.275', 'Eccrine sweat gland cells': '-0.329', 'Adipocytes (Skin)': '-0.375', 'Mitotic cells (Skin)': '0.009', 'Parietal cells': '-0.463', 'Chief cells': '-0.533', 'Gastric mucous cells': '-0.164', 'Gastric enteroendocrine cells': '-0.394', 'Mitotic cells (Stomach)': '0.067', 'Parafollicular cells': '-0.065', 'Thyroid glandular cells': '0.015', 'Mitotic cells (Thyroid)': '0.174', 'Adrenal cortex cells': '0.089', 'Adrenal medulla cells': '0.228', 'Mitotic cells (Adrenal gland)': '0.048', 'Minor salivary glandular cells': '0.071', 'Minor salivary gland ductal cells': '0.046', 'Minor salivary gland basal cells': '0.132', 'Mitotic cells (Minor salivary gland)': '0.017', 'Adipocytes (Minor salivary gland)': '0.008', 'Somatotropes': '-0.247', 'Lactotropes': '-0.400', 'Gonadotropes': '-0.289', 'Corticotropes': '-0.237', 'Thyrotropes': '-0.154', 'Undifferentiated cells (Pituitary gland)': '0.413', 'Mitotic cells (Spleen)': '-0.293', 'Platelets': '-0.210', 'Erythrocytes': '-0.092', 'Hematopoietic stem cells': '-0.233', 'B-cells (Spleen)': '0.146', 'NK-cells (Spleen)': '0.250', 'Amygdala excitatory': '28.5', 'Cerebellar inhibitory': '23.2', 'Cge interneuron': '25.3', 'Deep-layer corticothalamic and 6b': '19.6', 'Deep-layer intratelencephalic': '20.6', 'Deep-layer near-projecting': '19.7', 'Eccentric medium spiny neuron': '9.8', 'Hippocampal ca1-3': '31.9', 'Hippocampal ca4': '29.0', 'Hippocampal dentate gyrus': '14.4', 'Lamp5-lhx6 and chandelier': '16.6', 'Lower rhombic lip': '36.4', 'Mammillary body': '111.7', 'Medium spiny neuron': '22.2', 'Mge interneuron': '23.0', 'Midbrain-derived inhibitory': '27.8', 'Miscellaneous': '15.5', 'Splatter': '35.6', 'Thalamic excitatory': '40.4', 'Upper rhombic lip': '6.2', 'Upper-layer intratelencephalic': '16.9', 'Astrocyte': '202.0', 'Bergmann glia': '70.8', 'Central nervous system macrophage': '4.1', 'Choroid plexus epithelial cell': '6.6', 'Committed oligodendrocyte precursor': '49.9', 'Ependymal cell': '43.0', 'Oligodendrocyte': '94.1', 'Oligodendrocyte precursor cell': '81.5', 'Endothelial cell': '5.6', 'Pericyte': '2.1', 'Vascular associated smooth muscle cell': '3.5', 'Fibroblast': '18.8', 'Leukocyte': '11.6', 'Basophil': '0.4', 'Eosinophil': '1.8', 'Neutrophil': '0.2', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '1.1', 'GdT-cell': '0.1', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '1.2', 'Naive CD4 T-cell': '0.8', 'Memory CD8 T-cell': '0.9', 'Naive CD8 T-cell': '1.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.2', 'Plasmacytoid DC': '79.6', 'Myeloid DC': '4.9', 'NK-cell': '0.2', 'Total PBMC': '2.8', 'Vd2 gdTCR': '0.2', 'Memory CD4 T-cell Th1\\/Th17': '3.0', 'Memory CD4 T-cell Th17': '3.4', 'Memory CD4 T-cell Th2': '1.9', 'Non-Vd2 gdTCR': '0.9', 'Memory CD4 T-cell Th1': '1.7', 'Memory CD4 T-cell TFH': '1.9', 'Terminal effector memory CD4 T-cell': '0.7', 'Central memory CD8 T-cell': '0.6', 'Effector memory CD8 T-cell': '0.6', 'Terminal effector memory CD8 T-cell': '0.3', 'Non-switched memory B-cell': '1.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.4', 'Exhausted memory B-cell': '0.1', 'Progenitor cell': '12.3', 'Memory T-reg': '0.3', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.2'}
| null |
{'Adipose Tissue': 7.410737209302325, 'Adrenal Gland': 0.2748487131782945, 'Bladder': 36.7197619047619, 'Blood': 2.0795593110871904, 'Blood Vessel': 16.661655730337078, 'Brain': 7.587562225586677, 'Breast': 6.181703050108932, 'Cervix Uteri': 4.486052631578947, 'Colon': 9.80163543003851, 'Esophagus': 12.003066089965396, 'Fallopian Tube': 4.913666666666667, 'Heart': 29.380126132404182, 'Kidney': 3.972280898876405, 'Liver': 1.205875575221239, 'Lung': 6.115176297577855, 'Muscle': 5.38215292652553, 'Nerve': 4.988103715670436, 'Ovary': 1.717936111111111, 'Pancreas': 1.074822530487805, 'Pituitary': 2.4372636042402824, 'Prostate': 6.7676379591836735, 'Salivary Gland': 6.162654320987654, 'Skin': 48.32727125262576, 'Small Intestine': 11.919679144385029, 'Spleen': 2.687407053941909, 'Stomach': 11.379621169916437, 'Testis': 0.9416138504155124, 'Thyroid': 2.307166768759571, 'Uterus': 5.369323943661971, 'Vagina': 13.66455641025641}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[45.63, 52.69, 60.83, 56.52, 64.43, 65.28, 61.02, 71.55, 79.59, 92.04, 94.64, 95.25, 95.7, 96.51, 96.83, 95.93, 96.53, 97.24, 97.39, 97.0, 96.64, 96.58, 96.23, 94.18, 93.35, 93.61, 95.51, 97.42, 97.62, 97.76, 97.29, 96.94, 95.4, 96.76, 95.54, 94.5, 94.51, 95.14, 95.64, 97.52, 97.7, 97.59, 98.07, 98.36, 97.89, 97.37, 97.78, 97.6, 97.17, 96.2, 96.48, 95.66, 95.78, 94.47, 95.01, 94.37, 92.66, 90.11, 82.46, 80.25, 72.18, 63.3, 59.17, 42.54, 49.51, 50.6, 52.01, 50.19, 61.12, 68.48, 71.34, 73.25, 79.41, 88.7, 88.48, 93.08, 95.6, 96.63, 97.0, 96.68, 95.65, 92.87, 89.18, 93.05, 92.15, 91.64, 92.29, 94.75, 95.93, 96.44, 97.3, 97.11, 96.37, 96.99, 97.45, 96.17, 96.52, 96.99, 96.73, 95.7, 96.46, 96.29, 94.84, 95.44, 94.68, 89.17, 87.88, 91.14, 88.22, 85.71, 86.17, 91.3, 92.16, 94.03, 88.24, 93.84, 96.66, 97.03, 97.15, 97.94, 98.05, 97.94, 97.99, 98.09, 97.5, 95.55, 95.15, 94.85, 95.91, 95.51, 95.81, 96.65, 95.63, 96.7, 96.34, 96.93, 97.09, 96.17, 94.05, 92.71, 93.58, 94.17, 95.9, 97.24, 96.59, 97.66, 98.51, 98.57, 98.8, 98.84, 98.87, 98.78, 98.73, 98.26, 97.47, 98.4, 97.97, 97.68, 97.61, 97.74, 98.4, 98.37, 98.2, 98.71, 98.76, 98.62, 98.48, 97.87, 96.57, 93.89, 92.9, 92.35, 93.36, 94.9, 96.04, 97.17, 98.16, 98.44, 98.53, 98.71, 98.51, 98.67, 98.19, 98.63, 98.67, 98.73, 98.45, 98.31, 97.73, 97.73, 96.77, 96.6, 96.5, 97.44, 97.93, 98.58, 98.25, 98.45, 98.23, 97.76, 97.7, 97.95, 97.88, 98.08, 98.55, 98.73, 98.76, 98.45, 98.69, 98.48, 98.36, 98.07, 97.16, 96.07, 94.84, 94.85, 95.14, 94.86, 94.84, 94.72, 92.2, 91.7, 93.3, 90.68, 87.01, 88.26, 88.17, 84.9, 81.1, 79.7, 74.8, 73.19, 68.41, 66.03, 63.76, 61.52, 60.85, 55.15, 42.4]
|
[0.9, 0.57, 0.53, 0.32, 0.45, 0.1, 0.8, 0.85, 0.27, 0.51, 0.06, 0.5, 0.51, 0.2, 0.0, 0.41, 0.65, 0.38, 0.01, 0.1, 0.32, 0.22, 0.02, 0.56, 0.7, 0.3, 0.07, 0.14, 0.03, 0.37, 0.17, 0.51, 0.6, 0.04, 0.01, 0.19, 0.63, 0.55, 0.13, 0.0, 0.26, 0.51, 0.0, 0.05, 0.55, 0.18, 0.0, 0.35, 0.51, 0.13, 0.27, 0.81, 0.68, 0.6, 0.36, 0.08, 0.78, 0.33, 0.02, 0.52, 0.34, 0.91, 0.55, 0.99, 0.8, 0.7, 0.47, 0.52, 0.39, 0.34, 0.69, 0.8, 0.27, 0.08, 0.19, 0.02, 0.27, 0.12, 0.2, 0.49, 0.04, 0.28, 0.13, 0.93, 0.41, 0.86, 0.4, 0.02, 0.7, 0.18, 0.0, 0.39, 0.34, 0.01, 0.03, 0.39, 0.01, 0.04, 0.3, 0.41, 0.0, 0.06, 0.76, 0.39, 0.03, 0.33, 0.77, 0.63, 0.04, 0.55, 0.96, 0.13, 0.57, 0.29, 0.7, 0.44, 0.3, 0.2, 0.6, 0.01, 0.08, 0.0, 0.05, 0.0, 0.06, 0.37, 0.02, 0.85, 0.36, 0.2, 0.21, 0.15, 0.49, 0.54, 0.21, 0.24, 0.11, 0.07, 0.44, 0.92, 0.27, 0.29, 0.0, 0.15, 0.03, 0.02, 0.01, 0.01, 0.11, 0.0, 0.01, 0.01, 0.04, 0.4, 0.88, 0.12, 0.39, 0.17, 0.92, 0.76, 0.28, 0.15, 0.0, 0.15, 0.02, 0.28, 0.01, 0.2, 0.06, 0.63, 0.98, 0.45, 0.99, 0.44, 0.58, 0.09, 0.45, 0.01, 0.38, 0.0, 0.34, 0.16, 0.02, 0.08, 0.0, 0.0, 0.02, 0.01, 0.02, 0.0, 0.23, 0.58, 0.31, 0.01, 0.17, 0.06, 0.26, 0.11, 0.24, 0.44, 0.0, 0.63, 0.24, 0.4, 0.03, 0.1, 0.06, 0.04, 0.08, 0.04, 0.1, 0.03, 0.07, 0.07, 0.27, 0.73, 0.27, 0.27, 0.49, 0.58, 0.17, 0.39, 0.6, 0.54, 0.67, 0.58, 0.48, 0.64, 0.36, 0.71, 0.71, 0.55, 0.61, 0.42, 0.53, 0.72, 0.77, 0.86, 0.85]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 91.165188
| 0.32749
| 1,864
|
O43255
|
Q9HB71
| null |
degron_data
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
CACYBP
|
MASEELQKDLEEVKVLLEKATRKRVRDALTAEKSKIETEIKNKMQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLTGVHQVPTENVQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRWDYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAKGDTEF
|
Homo sapiens
|
Nucleus, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '80.6', 'Basal respiratory cells': '97.3', 'Club cells': '55.7', 'Ionocytes': '55.2', 'Mucus glandular cells': '46.6', 'Serous glandular cells': '34.4', 'Gastric mucus-secreting cells': '37.7', 'Proximal enterocytes': '78.9', 'Paneth cells': '71.4', 'Distal enterocytes': '65.0', 'Intestinal goblet cells': '62.3', 'Exocrine glandular cells': '-0.546', 'Basal prostatic cells': '72.2', 'Prostatic glandular cells': '59.6', 'Breast glandular cells': '-0.062', 'Breast myoepithelial cells': '-0.056', 'Glandular and luminal cells': '162.6', 'Secretory cells': '79.5', 'Basal keratinocytes': '99.0', 'Suprabasal keratinocytes': '81.6', 'Basal squamous epithelial cells': '72.0', 'Squamous epithelial cells': '86.4', 'Alveolar cells type 1': '-0.010', 'Alveolar cells type 2': '-0.212', 'Salivary duct cells': '49.1', 'Ductal cells': '0.431', 'Hepatocytes': '0.397', 'Cholangiocytes': '42.0', 'Proximal tubular cells': '0.179', 'Distal tubular cells': '89.1', 'Collecting duct cells': '38.9', 'Mesothelial cells': '0.098', 'Sertoli cells': '-0.295', 'Granulosa cells': '99.3', 'Enteroendocrine cells': '72.6', 'Pancreatic endocrine cells': '103.6', 'Leydig cells': '-0.288', 'Excitatory neurons': '21.6', 'Inhibitory neurons': '23.1', 'Cone photoreceptor cells': '96.9', 'Rod photoreceptor cells': '73.3', 'Bipolar cells': '62.5', 'Horizontal cells': '31.5', 'Astrocytes': '12.4', 'Oligodendrocyte precursor cells': '8.0', 'Oligodendrocytes': '26.1', 'Microglial cells': '12.5', 'Muller glia cells': '72.4', 'Schwann cells': '0.096', 'Spermatogonia': '0.075', 'Spermatocytes': '0.321', 'Early spermatids': '0.765', 'Late spermatids': '0.363', 'Oocytes': '446.3', 'Cytotrophoblasts': '265.2', 'Syncytiotrophoblasts': '144.3', 'Extravillous trophoblasts': '303.3', 'Endothelial cells': '71.2', 'Lymphatic endothelial cells': '73.8', 'Cardiomyocytes': '0.561', 'Skeletal myocytes': '0.332', 'Smooth muscle cells': '65.3', 'Adipocytes': '64.2', 'Melanocytes': '0.185', 'Fibroblasts': '81.7', 'Peritubular cells': '-0.145', 'Endometrial stromal cells': '60.3', 'Ovarian stromal cells': '143.1', 'Undifferentiated cells': '148.9', 'T-cells': '141.5', 'B-cells': '93.5', 'Plasma cells': '106.8', 'Nk-cells': '70.6', 'Granulocytes': '115.6', 'Monocytes': '48.1', 'Macrophages': '96.0', 'Hofbauer cells': '180.5', 'Kupffer cells': '48.0', 'Dendritic cells': '32.6', 'Langerhans cells': '0.316', 'Erythroid cells': '-0.046', 'Adipocytes (Subcutaneous)': '0.037', 'Adipocytes (Visceral)': '0.024', 'Breast glandular cells (progenitors)': '-0.059', 'Adipocytes (Breast)': '0.241', 'Colon enterocytes': '-0.166', 'Colon enteroendocrine cells': '0.283', 'Enteric glia cells': '0.209', 'Mitotic cells (Colon)': '-0.179', 'Mitotic cells (Heart)': '0.465', 'Podocytes': '0.006', 'Ascending Loop of Henle cells': '0.205', 'Intercalated cells': '-0.008', 'Cholangiocyte': '0.356', 'NK-cells (Liver)': '-0.201', 'Respiratory ciliated cells': '0.038', 'Mitotic cells (Lung)': '0.120', 'NK-cells (Lung)': '0.080', 'B-cells (Lung)': '-0.029', 'Alpha cells': '0.352', 'Beta cells': '0.166', 'Prostate glandular cells': '-0.242', 'Prostate basal glandular cells': '-0.055', 'Urothelial cells': '-0.014', 'Keratinocyte (other)': '0.295', 'Keratinocyte (granular)': '-0.148', 'Hair cortex cells': '0.011', 'Inner root sheath cells': '0.082', 'Outer root sheath cells': '0.217', 'Sebaceous gland cells': '0.130', 'Eccrine sweat gland cells': '0.103', 'Adipocytes (Skin)': '-0.119', 'Mitotic cells (Skin)': '0.425', 'Parietal cells': '-0.643', 'Chief cells': '-0.472', 'Gastric mucous cells': '-0.384', 'Gastric enteroendocrine cells': '-0.351', 'Mitotic cells (Stomach)': '0.091', 'Parafollicular cells': '0.066', 'Thyroid glandular cells': '0.376', 'Mitotic cells (Thyroid)': '0.132', 'Adrenal cortex cells': '0.387', 'Adrenal medulla cells': '0.028', 'Mitotic cells (Adrenal gland)': '0.299', 'Minor salivary glandular cells': '0.289', 'Minor salivary gland ductal cells': '-0.087', 'Minor salivary gland basal cells': '0.388', 'Mitotic cells (Minor salivary gland)': '0.447', 'Adipocytes (Minor salivary gland)': '0.096', 'Somatotropes': '-0.006', 'Lactotropes': '0.137', 'Gonadotropes': '0.060', 'Corticotropes': '0.105', 'Thyrotropes': '0.292', 'Undifferentiated cells (Pituitary gland)': '0.106', 'Mitotic cells (Spleen)': '0.140', 'Platelets': '-0.191', 'Erythrocytes': '0.017', 'Hematopoietic stem cells': '-0.126', 'B-cells (Spleen)': '0.123', 'NK-cells (Spleen)': '0.093', 'Amygdala excitatory': '20.2', 'Cerebellar inhibitory': '43.6', 'Cge interneuron': '36.1', 'Deep-layer corticothalamic and 6b': '30.4', 'Deep-layer intratelencephalic': '28.6', 'Deep-layer near-projecting': '32.5', 'Eccentric medium spiny neuron': '24.5', 'Hippocampal ca1-3': '23.8', 'Hippocampal ca4': '41.6', 'Hippocampal dentate gyrus': '38.8', 'Lamp5-lhx6 and chandelier': '33.6', 'Lower rhombic lip': '51.1', 'Mammillary body': '32.2', 'Medium spiny neuron': '24.0', 'Mge interneuron': '33.0', 'Midbrain-derived inhibitory': '39.1', 'Miscellaneous': '34.4', 'Splatter': '42.0', 'Thalamic excitatory': '41.6', 'Upper rhombic lip': '45.0', 'Upper-layer intratelencephalic': '28.9', 'Astrocyte': '15.2', 'Bergmann glia': '27.6', 'Central nervous system macrophage': '33.0', 'Choroid plexus epithelial cell': '24.9', 'Committed oligodendrocyte precursor': '26.7', 'Ependymal cell': '29.3', 'Oligodendrocyte': '39.1', 'Oligodendrocyte precursor cell': '26.3', 'Endothelial cell': '42.9', 'Pericyte': '35.2', 'Vascular associated smooth muscle cell': '26.9', 'Fibroblast': '28.8', 'Leukocyte': '72.4', 'Basophil': '46.5', 'Eosinophil': '27.9', 'Neutrophil': '36.3', 'Classical monocyte': '18.9', 'Non-classical monocyte': '33.1', 'Intermediate monocyte': '59.4', 'T-reg': '79.3', 'GdT-cell': '29.5', 'MAIT T-cell': '70.1', 'Memory CD4 T-cell': '42.2', 'Naive CD4 T-cell': '44.9', 'Memory CD8 T-cell': '36.3', 'Naive CD8 T-cell': '35.5', 'Memory B-cell': '43.3', 'Naive B-cell': '18.2', 'Plasmacytoid DC': '93.8', 'Myeloid DC': '67.2', 'NK-cell': '29.9', 'Total PBMC': '64.1', 'Vd2 gdTCR': '57.8', 'Memory CD4 T-cell Th1\\/Th17': '54.9', 'Memory CD4 T-cell Th17': '40.0', 'Memory CD4 T-cell Th2': '39.2', 'Non-Vd2 gdTCR': '48.8', 'Memory CD4 T-cell Th1': '45.2', 'Memory CD4 T-cell TFH': '38.8', 'Terminal effector memory CD4 T-cell': '60.0', 'Central memory CD8 T-cell': '64.0', 'Effector memory CD8 T-cell': '65.2', 'Terminal effector memory CD8 T-cell': '55.9', 'Non-switched memory B-cell': '56.9', 'Plasmablast': '93.2', 'Switched memory B-cell': '62.0', 'Exhausted memory B-cell': '69.2', 'Progenitor cell': '55.0', 'Memory T-reg': '37.9', 'Naive CD4 T-cell activated': '56.6', 'Naive CD8 T-cell activated': '56.5', 'Naive T-reg': '41.6'}
|
1X5M, 2A25, 2A26
|
{'Adipose Tissue': 34.00395681063123, 'Adrenal Gland': 27.9329496124031, 'Bladder': 42.15571428571428, 'Blood': 31.604480086114098, 'Blood Vessel': 38.19397752808989, 'Brain': 58.70836373959122, 'Breast': 29.872331154684097, 'Cervix Uteri': 40.594210526315784, 'Colon': 32.665160462130935, 'Esophagus': 30.466315570934256, 'Fallopian Tube': 33.46888888888889, 'Heart': 16.64826051103368, 'Kidney': 20.995685393258427, 'Liver': 13.42224336283186, 'Lung': 38.34101384083045, 'Muscle': 22.51199501867995, 'Nerve': 42.15281098546042, 'Ovary': 61.33833333333333, 'Pancreas': 10.134585365853658, 'Pituitary': 40.089858657243816, 'Prostate': 23.78472244897959, 'Salivary Gland': 23.587462962962963, 'Skin': 34.581728026533995, 'Small Intestine': 27.22003743315508, 'Spleen': 30.47680497925311, 'Stomach': 24.768972144846796, 'Testis': 46.5023268698061, 'Thyroid': 27.763803981623276, 'Uterus': 42.24845070422535, 'Vagina': 34.78384615384615}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
[56.73, 73.25, 77.55, 84.4, 87.65, 87.84, 88.81, 92.43, 91.08, 92.24, 93.39, 93.79, 92.77, 92.99, 94.6, 93.7, 91.7, 93.08, 93.08, 90.44, 91.83, 94.04, 92.78, 91.34, 92.6, 92.64, 91.03, 91.85, 92.38, 92.07, 92.26, 90.2, 92.02, 91.17, 90.93, 89.26, 89.69, 88.0, 87.98, 88.74, 87.59, 83.53, 82.57, 80.2, 76.54, 68.79, 67.58, 60.61, 57.25, 53.94, 46.55, 50.5, 47.85, 48.82, 47.41, 46.65, 43.11, 41.34, 43.5, 39.23, 41.28, 39.45, 43.87, 34.99, 44.2, 42.19, 39.86, 46.95, 51.41, 63.79, 81.81, 89.57, 92.52, 94.06, 93.78, 89.73, 91.06, 95.65, 96.09, 97.81, 97.68, 97.38, 96.72, 96.33, 97.52, 97.84, 98.17, 98.16, 98.13, 97.89, 97.36, 96.3, 95.15, 95.13, 94.1, 95.47, 94.34, 94.43, 92.73, 93.21, 90.22, 93.11, 93.87, 95.43, 96.25, 97.17, 97.76, 98.25, 97.88, 97.25, 97.5, 97.03, 97.84, 96.79, 97.41, 96.4, 95.96, 94.09, 89.51, 91.24, 87.65, 86.54, 91.82, 94.1, 95.74, 95.64, 95.3, 95.64, 94.92, 94.97, 95.3, 97.67, 97.01, 96.89, 97.62, 98.21, 97.81, 97.51, 97.03, 97.14, 98.15, 97.61, 97.17, 96.72, 96.86, 95.62, 96.68, 96.15, 96.13, 97.08, 97.58, 98.1, 98.09, 98.16, 98.21, 98.16, 97.21, 96.14, 93.03, 95.0, 94.52, 95.47, 96.85, 95.29, 95.94, 95.55, 95.55, 94.05, 91.24, 90.94, 92.02, 88.32, 84.52, 86.11, 80.82, 75.74, 67.05, 59.68, 55.69, 53.58, 49.95, 50.24, 54.4, 56.77, 51.5, 58.6, 59.99, 64.53, 63.13, 64.54, 67.6, 68.89, 66.64, 67.17, 67.65, 67.9, 65.66, 65.83, 62.18, 64.27, 63.56, 59.25, 58.51, 64.78, 61.44, 62.85, 66.97, 68.8, 70.62, 66.76, 69.75, 76.83, 74.55, 73.69, 76.23, 74.06, 71.53, 72.57, 71.11, 66.4, 63.97, 62.96, 61.61, 58.72, 52.1, 44.89, 40.4, 38.71]
|
[0.73, 0.48, 0.39, 0.54, 0.59, 0.1, 0.51, 0.7, 0.4, 0.14, 0.55, 0.59, 0.09, 0.37, 0.45, 0.43, 0.22, 0.83, 0.76, 0.13, 0.87, 0.79, 0.72, 0.87, 0.48, 0.52, 0.53, 0.54, 0.16, 0.51, 0.54, 0.41, 0.29, 0.52, 0.56, 0.08, 0.43, 0.5, 0.46, 0.15, 0.63, 0.46, 0.37, 0.55, 0.51, 0.61, 0.68, 0.59, 0.65, 0.7, 0.75, 0.72, 0.84, 0.8, 0.85, 0.95, 0.98, 1.0, 0.99, 1.0, 0.99, 1.0, 0.95, 0.92, 0.8, 0.75, 0.87, 0.6, 0.91, 0.42, 0.61, 0.56, 0.31, 0.85, 0.11, 0.75, 0.81, 0.35, 0.44, 0.34, 0.36, 0.34, 0.39, 0.6, 0.57, 0.31, 0.01, 0.26, 0.0, 0.36, 0.0, 0.74, 0.07, 0.62, 0.14, 0.0, 0.5, 0.87, 0.19, 0.53, 0.7, 0.73, 0.19, 0.02, 0.39, 0.25, 0.58, 0.11, 0.34, 0.5, 0.43, 0.19, 0.0, 0.36, 0.02, 0.32, 0.0, 0.37, 0.57, 0.02, 0.76, 0.33, 0.35, 0.17, 0.21, 0.27, 0.03, 0.71, 0.05, 0.65, 0.51, 0.01, 0.15, 0.39, 0.2, 0.03, 0.32, 0.43, 0.94, 0.23, 0.12, 0.36, 0.38, 0.53, 0.44, 0.56, 0.77, 0.3, 0.24, 0.0, 0.08, 0.0, 0.1, 0.01, 0.39, 0.04, 0.55, 0.66, 0.45, 0.75, 0.24, 0.74, 0.02, 0.68, 0.23, 0.0, 0.12, 0.33, 0.5, 0.32, 0.38, 0.53, 0.48, 0.46, 0.5, 0.76, 0.62, 0.63, 0.59, 0.61, 0.71, 0.52, 0.82, 0.94, 0.31, 0.67, 0.77, 0.66, 0.55, 0.17, 0.59, 0.64, 0.48, 0.34, 0.54, 0.58, 0.43, 0.43, 0.36, 0.6, 0.85, 0.12, 0.74, 0.64, 0.6, 0.5, 0.25, 0.68, 0.65, 0.35, 0.42, 0.63, 0.52, 0.72, 0.54, 0.45, 0.48, 0.75, 0.5, 0.74, 0.7, 0.73, 0.72, 0.67, 0.88, 0.81, 0.96, 1.0]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 81.25136
| 0.485833
| 2,633
|
O43255
|
Q9NRM7
|
nan, 25438054
|
degron_data, UbiNet, UbiBrowser
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
LATS2
|
MRPKTFPATTYSGNSRQRLQEIREGLKQPSKSSVQGLPAGPNSDTSLDAKVLGSKDATRQQQQMRATPKFGPYQKALREIRYSLLPFANESGTSAAAEVNRQMLQELVNAGCDQEMAGRALKQTGSRSIEAALEYISKMGYLDPRNEQIVRVIKQTSPGKGLMPTPVTRRPSFEGTGDSFASYHQLSGTPYEGPSFGADGPTALEEMPRPYVDYLFPGVGPHGPGHQHQHPPKGYGASVEAAGAHFPLQGAHYGRPHLLVPGEPLGYGVQRSPSFQSKTPPETGGYASLPTKGQGGPPGAGLAFPPPAAGLYVPHPHHKQAGPAAHQLHVLGSRSQVFASDSPPQSLLTPSRNSLNVDLYELGSTSVQQWPAATLARRDSLQKPGLEAPPRAHVAFRPDCPVPSRTNSFNSHQPRPGPPGKAEPSLPAPNTVTAVTAAHILHPVKSVRVLRPEPQTAVGPSHPAWVPAPAPAPAPAPAPAAEGLDAKEEHALALGGAGAFPLDVEYGGPDRRCPPPPYPKHLLLRSKSEQYDLDSLCAGMEQSLRAGPNEPEGGDKSRKSAKGDKGGKDKKQIQTSPVPVRKNSRDEEKRESRIKSYSPYAFKFFMEQHVENVIKTYQQKVNRRLQLEQEMAKAGLCEAEQEQMRKILYQKESNYNRLKRAKMDKSMFVKIKTLGIGAFGEVCLACKVDTHALYAMKTLRKKDVLNRNQVAHVKAERDILAEADNEWVVKLYYSFQDKDSLYFVMDYIPGGDMMSLLIRMEVFPEHLARFYIAELTLAIESVHKMGFIHRDIKPDNILIDLDGHIKLTDFGLCTGFRWTHNSKYYQKGSHVRQDSMEPSDLWDDVSNCRCGDRLKTLEQRARKQHQRCLAHSLVGTPNYIAPEVLLRKGYTQLCDWWSVGVILFEMLVGQPPFLAPTPTETQLKVINWENTLHIPAQVKLSPEARDLITKLCCSADHRLGRNGADDLKAHPFFSAIDFSSDIRKQPAPYVPTISHPMDTSNFDPVDEESPWNDASEGSTKAWDTLTSPNNKHPEHAFYEFTFRRFFDDNGYPFRCPKPSGAEASQAESSDLESSDLVDQTEGCQPVYV
|
Homo sapiens
|
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, Cytoplasm, cytoskeleton, spindle pole, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '18.4', 'Basal respiratory cells': '8.2', 'Club cells': '10.4', 'Ionocytes': '9.2', 'Mucus glandular cells': '22.4', 'Serous glandular cells': '8.7', 'Gastric mucus-secreting cells': '6.5', 'Proximal enterocytes': '0.6', 'Paneth cells': '4.1', 'Distal enterocytes': '4.1', 'Intestinal goblet cells': '2.0', 'Exocrine glandular cells': '-0.480', 'Basal prostatic cells': '9.2', 'Prostatic glandular cells': '16.8', 'Breast glandular cells': '-0.037', 'Breast myoepithelial cells': '0.184', 'Glandular and luminal cells': '63.8', 'Secretory cells': '12.0', 'Basal keratinocytes': '18.8', 'Suprabasal keratinocytes': '15.5', 'Basal squamous epithelial cells': '16.2', 'Squamous epithelial cells': '9.2', 'Alveolar cells type 1': '0.349', 'Alveolar cells type 2': '-0.201', 'Salivary duct cells': '25.0', 'Ductal cells': '0.714', 'Hepatocytes': '0.396', 'Cholangiocytes': '17.2', 'Proximal tubular cells': '0.114', 'Distal tubular cells': '6.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.248', 'Sertoli cells': '-0.485', 'Granulosa cells': '9.2', 'Enteroendocrine cells': '0.6', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '-0.478', 'Excitatory neurons': '0.6', 'Inhibitory neurons': '0.5', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.6', 'Bipolar cells': '0.5', 'Horizontal cells': '1.9', 'Astrocytes': '11.5', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '8.2', 'Microglial cells': '20.6', 'Muller glia cells': '5.7', 'Schwann cells': '0.146', 'Spermatogonia': '-0.197', 'Spermatocytes': '0.111', 'Early spermatids': '0.692', 'Late spermatids': '0.655', 'Oocytes': '13.2', 'Cytotrophoblasts': '24.2', 'Syncytiotrophoblasts': '50.2', 'Extravillous trophoblasts': '8.5', 'Endothelial cells': '37.4', 'Lymphatic endothelial cells': '46.5', 'Cardiomyocytes': '0.545', 'Skeletal myocytes': '-0.026', 'Smooth muscle cells': '31.4', 'Adipocytes': '38.0', 'Melanocytes': '0.023', 'Fibroblasts': '35.7', 'Peritubular cells': '-0.290', 'Endometrial stromal cells': '33.4', 'Ovarian stromal cells': '9.5', 'Undifferentiated cells': '1.2', 'T-cells': '7.8', 'B-cells': '3.7', 'Plasma cells': '9.0', 'Nk-cells': '28.7', 'Granulocytes': '17.2', 'Monocytes': '55.9', 'Macrophages': '31.6', 'Hofbauer cells': '12.7', 'Kupffer cells': '19.2', 'Dendritic cells': '10.5', 'Langerhans cells': '-0.032', 'Erythroid cells': '0.011', 'Adipocytes (Subcutaneous)': '-0.312', 'Adipocytes (Visceral)': '-0.139', 'Breast glandular cells (progenitors)': '-0.082', 'Adipocytes (Breast)': '0.005', 'Colon enterocytes': '-0.166', 'Colon enteroendocrine cells': '0.216', 'Enteric glia cells': '-0.016', 'Mitotic cells (Colon)': '-0.090', 'Mitotic cells (Heart)': '0.505', 'Podocytes': '-0.057', 'Ascending Loop of Henle cells': '0.511', 'Intercalated cells': '0.022', 'Cholangiocyte': '0.441', 'NK-cells (Liver)': '-0.224', 'Respiratory ciliated cells': '-0.016', 'Mitotic cells (Lung)': '-0.194', 'NK-cells (Lung)': '0.253', 'B-cells (Lung)': '0.060', 'Alpha cells': '0.401', 'Beta cells': '0.236', 'Prostate glandular cells': '-0.389', 'Prostate basal glandular cells': '-0.248', 'Urothelial cells': '-0.177', 'Keratinocyte (other)': '-0.236', 'Keratinocyte (granular)': '-0.050', 'Hair cortex cells': '0.131', 'Inner root sheath cells': '0.172', 'Outer root sheath cells': '0.171', 'Sebaceous gland cells': '0.015', 'Eccrine sweat gland cells': '0.296', 'Adipocytes (Skin)': '0.288', 'Mitotic cells (Skin)': '0.094', 'Parietal cells': '-0.699', 'Chief cells': '-0.597', 'Gastric mucous cells': '-0.573', 'Gastric enteroendocrine cells': '-0.458', 'Mitotic cells (Stomach)': '-0.193', 'Parafollicular cells': '0.114', 'Thyroid glandular cells': '0.383', 'Mitotic cells (Thyroid)': '-0.087', 'Adrenal cortex cells': '0.340', 'Adrenal medulla cells': '0.079', 'Mitotic cells (Adrenal gland)': '0.100', 'Minor salivary glandular cells': '0.551', 'Minor salivary gland ductal cells': '0.037', 'Minor salivary gland basal cells': '0.353', 'Mitotic cells (Minor salivary gland)': '0.428', 'Adipocytes (Minor salivary gland)': '0.335', 'Somatotropes': '-0.389', 'Lactotropes': '-0.443', 'Gonadotropes': '0.042', 'Corticotropes': '-0.247', 'Thyrotropes': '-0.113', 'Undifferentiated cells (Pituitary gland)': '0.519', 'Mitotic cells (Spleen)': '-0.259', 'Platelets': '-0.057', 'Erythrocytes': '-0.043', 'Hematopoietic stem cells': '-0.169', 'B-cells (Spleen)': '0.012', 'NK-cells (Spleen)': '0.233', 'Amygdala excitatory': '1.0', 'Cerebellar inhibitory': '6.0', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '1.3', 'Deep-layer intratelencephalic': '0.6', 'Deep-layer near-projecting': '0.6', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '14.8', 'Hippocampal ca4': '76.7', 'Hippocampal dentate gyrus': '0.9', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.5', 'Mammillary body': '0.4', 'Medium spiny neuron': '0.4', 'Mge interneuron': '2.3', 'Midbrain-derived inhibitory': '13.5', 'Miscellaneous': '1.3', 'Splatter': '2.2', 'Thalamic excitatory': '3.9', 'Upper rhombic lip': '15.0', 'Upper-layer intratelencephalic': '0.5', 'Astrocyte': '32.9', 'Bergmann glia': '37.7', 'Central nervous system macrophage': '30.9', 'Choroid plexus epithelial cell': '94.2', 'Committed oligodendrocyte precursor': '16.3', 'Ependymal cell': '39.2', 'Oligodendrocyte': '15.7', 'Oligodendrocyte precursor cell': '8.1', 'Endothelial cell': '124.1', 'Pericyte': '84.4', 'Vascular associated smooth muscle cell': '82.2', 'Fibroblast': '123.5', 'Leukocyte': '27.9', 'Basophil': '5.8', 'Eosinophil': '0.5', 'Neutrophil': '12.5', 'Classical monocyte': '35.5', 'Non-classical monocyte': '12.9', 'Intermediate monocyte': '7.9', 'T-reg': '0.1', 'GdT-cell': '0.4', 'MAIT T-cell': '8.9', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.7', 'Memory B-cell': '0.0', 'Naive B-cell': '2.1', 'Plasmacytoid DC': '1.2', 'Myeloid DC': '10.4', 'NK-cell': '28.2', 'Total PBMC': '4.4', 'Vd2 gdTCR': '4.6', 'Memory CD4 T-cell Th1\\/Th17': '9.8', 'Memory CD4 T-cell Th17': '2.8', 'Memory CD4 T-cell Th2': '1.0', 'Non-Vd2 gdTCR': '3.6', 'Memory CD4 T-cell Th1': '5.2', 'Memory CD4 T-cell TFH': '0.2', 'Terminal effector memory CD4 T-cell': '4.4', 'Central memory CD8 T-cell': '0.6', 'Effector memory CD8 T-cell': '2.1', 'Terminal effector memory CD8 T-cell': '4.1', 'Non-switched memory B-cell': '1.6', 'Plasmablast': '2.3', 'Switched memory B-cell': '1.2', 'Exhausted memory B-cell': '2.0', 'Progenitor cell': '5.7', 'Memory T-reg': '0.2', 'Naive CD4 T-cell activated': '0.2', 'Naive CD8 T-cell activated': '0.6', 'Naive T-reg': '0.1'}
|
4ZRI
|
{'Adipose Tissue': 33.723958471760795, 'Adrenal Gland': 14.39301550387597, 'Bladder': 26.68809523809524, 'Blood': 5.138888805166846, 'Blood Vessel': 46.64432958801498, 'Brain': 2.651930052990159, 'Breast': 26.026925925925926, 'Cervix Uteri': 24.481315789473683, 'Colon': 21.11655840821566, 'Esophagus': 23.068698269896196, 'Fallopian Tube': 25.103333333333335, 'Heart': 10.02873449477352, 'Kidney': 8.150550561797752, 'Liver': 4.539637168141593, 'Lung': 29.508737024221453, 'Muscle': 14.94353798256538, 'Nerve': 40.003618739903075, 'Ovary': 26.88305555555555, 'Pancreas': 3.75455487804878, 'Pituitary': 5.475971731448763, 'Prostate': 18.183363265306124, 'Salivary Gland': 11.2839012345679, 'Skin': 22.71388225538972, 'Small Intestine': 12.491080213903745, 'Spleen': 11.488738589211618, 'Stomach': 13.640871866295264, 'Testis': 37.91648199445984, 'Thyroid': 31.38495252679939, 'Uterus': 31.373309859154933, 'Vagina': 21.496089743589742}
|
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0.9, 0.89, 0.88, 0.93, 0.87, 0.93, 0.89, 0.95, 0.91, 0.91, 0.95, 0.84, 0.96, 0.97, 0.98, 1.0, 1.0, 1.0, 0.96, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.85, 1.0, 0.71, 0.86, 1.0, 0.83, 1.0, 0.92, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.92, 1.0, 0.95, 0.93, 0.98, 0.94, 0.94, 0.97, 0.95, 0.84, 0.93, 0.78, 0.71, 0.91, 0.83, 0.8, 0.85, 0.86, 0.88, 0.88, 0.9, 0.9, 0.86, 0.9, 0.88, 0.81, 0.9, 0.85, 0.87, 0.95, 0.87, 0.9, 0.86, 0.88, 0.82, 0.87, 0.88, 0.84, 0.95, 0.96, 0.97, 1.0, 0.92, 1.0, 0.99, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.98, 0.96, 0.96, 0.96, 0.62, 0.96, 0.57, 0.58, 0.86, 0.85, 0.74, 0.62, 0.91, 0.88, 0.93, 0.81, 1.0, 0.71, 1.0, 0.81, 0.73, 0.87, 0.73, 0.75, 0.94, 0.89, 0.81, 0.89, 0.98, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 0.89, 0.97, 0.89, 0.89, 0.89, 0.86, 0.93, 0.84, 0.69, 0.69, 0.73, 0.85, 0.72, 0.84, 0.87, 0.86, 0.86, 0.86, 0.83, 0.91, 0.84, 0.9, 0.76, 0.85, 0.98, 0.78, 0.8, 0.73, 0.86, 0.57, 0.9, 0.46, 0.35, 0.78, 0.47, 0.01, 0.54, 0.56, 0.16, 0.38, 0.45, 0.54, 0.2, 0.45, 0.47, 0.46, 0.26, 0.52, 0.49, 0.33, 0.26, 0.69, 0.54, 0.27, 0.27, 0.26, 0.58, 0.28, 0.49, 0.53, 0.38, 0.16, 0.33, 0.48, 0.43, 0.02, 0.66, 0.69, 0.42, 0.76, 0.2, 0.55, 0.75, 0.66, 0.28, 0.22, 0.41, 0.4, 0.2, 0.23, 0.57, 0.39, 0.2, 0.63, 0.57, 0.5, 0.17, 0.42, 0.46, 0.22, 0.35, 0.57, 0.37, 0.62, 0.73, 0.47, 0.88, 0.16, 0.52, 0.56, 0.71, 0.4, 0.1, 0.54, 0.45, 0.41, 0.47, 0.14, 0.1, 0.29, 0.3, 0.5, 0.32, 0.24, 0.15, 0.21, 0.28, 0.04, 0.0, 0.01, 0.22, 0.06, 0.46, 0.8, 0.56, 0.69, 0.08, 0.12, 0.07, 0.1, 0.05, 0.15, 0.17, 0.05, 0.31, 0.1, 0.29, 0.28, 0.0, 0.26, 0.77, 0.32, 0.46, 0.25, 0.07, 0.0, 0.11, 0.07, 0.11, 0.01, 0.03, 0.15, 0.18, 0.0, 0.02, 0.24, 0.3, 0.05, 0.67, 0.31, 0.62, 0.13, 0.03, 0.03, 0.22, 0.0, 0.17, 0.11, 0.01, 0.03, 0.36, 0.51, 0.75, 0.38, 0.17, 0.0, 0.03, 0.0, 0.0, 0.07, 0.14, 0.04, 0.06, 0.03, 0.1, 0.0, 0.18, 0.0, 0.12, 0.14, 0.04, 0.06, 0.14, 0.53, 0.37, 0.43, 0.5, 0.04, 0.43, 0.24, 0.59, 0.04, 0.0, 0.19, 0.05, 0.01, 0.0, 0.0, 0.0, 0.01, 0.0, 0.15, 0.01, 0.0, 0.13, 0.17, 0.0, 0.14, 0.69, 0.26, 0.39, 0.05, 0.06, 0.02, 0.23, 0.2, 0.02, 0.22, 0.0, 0.28, 0.04, 0.02, 0.19, 0.01, 0.13, 0.25, 0.55, 0.0, 0.03, 0.0, 0.13, 0.0, 0.18, 0.43, 0.0, 0.15, 0.43, 0.02, 0.22, 0.11, 0.82, 0.4, 0.68, 0.11, 0.06, 0.41, 0.03, 0.68, 0.33, 0.32, 0.28, 0.83, 0.71, 0.93, 0.71, 0.89, 0.58, 0.39, 0.49, 0.23, 0.41, 0.34, 0.53, 0.57, 0.94, 0.81, 0.3, 0.81, 0.7, 0.63, 0.71, 0.71, 0.68, 0.92, 0.66, 0.85, 0.95, 0.85, 0.84, 0.86, 0.84, 0.45, 0.49, 0.59, 0.69, 0.35, 0.63, 0.25, 0.59, 0.38, 0.31, 0.31, 0.53, 0.2, 0.47, 0.63, 0.38, 0.57, 0.58, 0.35, 0.16, 0.09, 0.06, 0.12, 0.19, 0.03, 0.08, 0.14, 0.25, 0.1, 0.43, 0.48, 0.77, 0.64, 0.41, 0.58, 0.42, 0.09, 0.04, 0.0, 0.01, 0.0, 0.02, 0.0, 0.0, 0.0, 0.0, 0.0, 0.03, 0.04, 0.01, 0.05, 0.18, 0.45, 0.57, 0.02, 0.2, 0.0, 0.39, 0.15, 0.78, 0.42, 0.31, 0.48, 0.37, 0.0, 0.2, 0.62, 0.26, 0.0, 0.35, 0.48, 0.19, 0.93, 0.65, 0.24, 0.19, 0.65, 0.27, 0.28, 0.88, 0.84, 0.32, 0.92, 0.21, 0.21, 0.73, 0.44, 0.0, 0.62, 0.32, 0.0, 0.0, 0.46, 0.38, 0.0, 0.0, 0.11, 0.39, 0.27, 0.66, 0.79, 0.01, 0.16, 0.06, 0.6, 0.84, 0.34, 0.08, 0.57, 0.29, 0.01, 0.18, 0.74, 0.06, 0.53, 0.0, 0.02, 0.78, 0.83, 0.22, 0.5, 0.21, 0.83, 0.38, 0.38, 0.02, 0.16, 0.72, 0.44, 0.9, 0.12, 0.49, 0.25, 0.61, 0.07, 0.75, 0.15, 0.81, 0.53, 0.36, 0.47, 0.09, 0.11, 0.63, 0.06, 0.2, 0.39, 0.89, 0.28, 0.77, 0.65, 0.93, 0.28, 0.75, 0.27, 0.65, 0.87, 0.45, 0.79, 0.88, 0.81, 0.5, 0.56, 0.86, 0.51, 0.39, 0.74, 0.74, 0.76, 0.58, 0.55, 0.88, 0.8, 0.83, 0.83, 0.43, 0.51, 0.59, 0.16, 0.08, 0.08, 0.26, 0.43, 0.03, 0.64, 0.12, 0.23, 0.13, 0.21, 0.79, 0.4, 0.91, 0.57, 0.86, 0.82, 0.23, 0.19, 0.81, 0.74, 0.59, 0.96, 0.91, 0.92, 0.78, 0.84, 0.89, 0.87, 0.93, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.91, 1.0, 0.94, 0.98, 0.97, 0.88, 0.9, 0.9, 0.77, 0.86, 0.92, 0.96]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 56.252748
| 0.654899
| 386
|
O43255
|
Q9NS87
|
22199232, hUbiquitome
|
UbiNet, UbiBrowser, 31181401
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
KIF15
|
MAPGCKTELRSVTNGQSNQPSNEGDAIKVFVRIRPPAERSGSADGEQNLCLSVLSSTSLRLHSNPEPKTFTFDHVADVDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVIPRSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLDSASAGLYLREHIKKGVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEKSNEIVNIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGNGKQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAVVNEDTQGNVSQLQAEVKRLKEQLAELASGQTPPESFLTRDKKKTNYMEYFQEAMLFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMIVKFREDQIIRLEKLHKESRGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRRLRLLEPVKRAQEMDAQTIAKLEKAFSEISGMEKSDKNQQGFSPKAQKEPCLFANTEKLKAQLLQIQTELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLENLLEATKACKRQEVSQLNKIHAETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNSSILDNDILNEPVPPEMNEQAFEAISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYNSALVDREESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEMLRKQVECLAEENGKLVGHQNLHQKIQYVVRLKKENVRLAEETEKLRAENVFLKEKKRSES
|
Homo sapiens
|
Cytoplasm, Cytoplasm, cytoskeleton, spindle
|
Group enriched (bone marrow, lymphoid tissue, testis)
|
{'Ciliated cells': '0.7', 'Basal respiratory cells': '0.8', 'Club cells': '0.8', 'Ionocytes': '0.4', 'Mucus glandular cells': '0.6', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '4.7', 'Proximal enterocytes': '0.2', 'Paneth cells': '0.0', 'Distal enterocytes': '0.1', 'Intestinal goblet cells': '1.7', 'Exocrine glandular cells': '-0.334', 'Basal prostatic cells': '0.1', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.159', 'Breast myoepithelial cells': '0.170', 'Glandular and luminal cells': '1.5', 'Secretory cells': '0.4', 'Basal keratinocytes': '4.0', 'Suprabasal keratinocytes': '1.3', 'Basal squamous epithelial cells': '0.9', 'Squamous epithelial cells': '6.0', 'Alveolar cells type 1': '-0.156', 'Alveolar cells type 2': '-0.008', 'Salivary duct cells': '1.0', 'Ductal cells': '0.525', 'Hepatocytes': '0.195', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.080', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.220', 'Sertoli cells': '-0.495', 'Granulosa cells': '1.8', 'Enteroendocrine cells': '1.6', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.525', 'Excitatory neurons': '3.1', 'Inhibitory neurons': '3.6', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.0', 'Horizontal cells': '0.6', 'Astrocytes': '2.5', 'Oligodendrocyte precursor cells': '2.8', 'Oligodendrocytes': '4.3', 'Microglial cells': '0.0', 'Muller glia cells': '0.4', 'Schwann cells': '0.168', 'Spermatogonia': '-0.206', 'Spermatocytes': '0.241', 'Early spermatids': '0.787', 'Late spermatids': '0.620', 'Oocytes': '5.9', 'Cytotrophoblasts': '3.5', 'Syncytiotrophoblasts': '1.1', 'Extravillous trophoblasts': '6.1', 'Endothelial cells': '0.8', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.450', 'Skeletal myocytes': '0.005', 'Smooth muscle cells': '0.8', 'Adipocytes': '0.2', 'Melanocytes': '0.495', 'Fibroblasts': '1.0', 'Peritubular cells': '-0.339', 'Endometrial stromal cells': '1.2', 'Ovarian stromal cells': '0.2', 'Undifferentiated cells': '11.8', 'T-cells': '2.0', 'B-cells': '1.2', 'Plasma cells': '11.0', 'Nk-cells': '1.3', 'Granulocytes': '0.2', 'Monocytes': '1.1', 'Macrophages': '2.1', 'Hofbauer cells': '2.8', 'Kupffer cells': '1.2', 'Dendritic cells': '1.6', 'Langerhans cells': '0.260', 'Erythroid cells': '0.192', 'Adipocytes (Subcutaneous)': '-0.133', 'Adipocytes (Visceral)': '-0.211', 'Breast glandular cells (progenitors)': '0.113', 'Adipocytes (Breast)': '-0.043', 'Colon enterocytes': '0.176', 'Colon enteroendocrine cells': '0.010', 'Enteric glia cells': '-0.085', 'Mitotic cells (Colon)': '0.368', 'Mitotic cells (Heart)': '0.659', 'Podocytes': '-0.106', 'Ascending Loop of Henle cells': '0.398', 'Intercalated cells': '-0.050', 'Cholangiocyte': '0.322', 'NK-cells (Liver)': '-0.062', 'Respiratory ciliated cells': '0.024', 'Mitotic cells (Lung)': '0.759', 'NK-cells (Lung)': '-0.006', 'B-cells (Lung)': '0.021', 'Alpha cells': '0.240', 'Beta cells': '0.160', 'Prostate glandular cells': '-0.145', 'Prostate basal glandular cells': '0.080', 'Urothelial cells': '0.178', 'Keratinocyte (other)': '0.297', 'Keratinocyte (granular)': '-0.213', 'Hair cortex cells': '0.062', 'Inner root sheath cells': '0.214', 'Outer root sheath cells': '0.248', 'Sebaceous gland cells': '0.068', 'Eccrine sweat gland cells': '-0.040', 'Adipocytes (Skin)': '-0.193', 'Mitotic cells (Skin)': '0.861', 'Parietal cells': '-0.248', 'Chief cells': '-0.256', 'Gastric mucous cells': '0.226', 'Gastric enteroendocrine cells': '-0.100', 'Mitotic cells (Stomach)': '0.790', 'Parafollicular cells': '0.002', 'Thyroid glandular cells': '0.034', 'Mitotic cells (Thyroid)': '0.577', 'Adrenal cortex cells': '0.428', 'Adrenal medulla cells': '0.133', 'Mitotic cells (Adrenal gland)': '0.899', 'Minor salivary glandular cells': '0.138', 'Minor salivary gland ductal cells': '-0.295', 'Minor salivary gland basal cells': '0.681', 'Mitotic cells (Minor salivary gland)': '0.944', 'Adipocytes (Minor salivary gland)': '0.174', 'Somatotropes': '-0.099', 'Lactotropes': '-0.074', 'Gonadotropes': '0.100', 'Corticotropes': '-0.246', 'Thyrotropes': '-0.018', 'Undifferentiated cells (Pituitary gland)': '0.379', 'Mitotic cells (Spleen)': '0.941', 'Platelets': '0.127', 'Erythrocytes': '0.352', 'Hematopoietic stem cells': '0.366', 'B-cells (Spleen)': '-0.145', 'NK-cells (Spleen)': '-0.163', 'Amygdala excitatory': '6.7', 'Cerebellar inhibitory': '6.4', 'Cge interneuron': '5.9', 'Deep-layer corticothalamic and 6b': '5.1', 'Deep-layer intratelencephalic': '6.1', 'Deep-layer near-projecting': '5.3', 'Eccentric medium spiny neuron': '9.6', 'Hippocampal ca1-3': '6.8', 'Hippocampal ca4': '2.9', 'Hippocampal dentate gyrus': '9.8', 'Lamp5-lhx6 and chandelier': '6.4', 'Lower rhombic lip': '4.3', 'Mammillary body': '4.1', 'Medium spiny neuron': '6.5', 'Mge interneuron': '5.5', 'Midbrain-derived inhibitory': '6.8', 'Miscellaneous': '6.4', 'Splatter': '5.3', 'Thalamic excitatory': '4.3', 'Upper rhombic lip': '3.0', 'Upper-layer intratelencephalic': '5.8', 'Astrocyte': '7.3', 'Bergmann glia': '7.2', 'Central nervous system macrophage': '3.9', 'Choroid plexus epithelial cell': '2.4', 'Committed oligodendrocyte precursor': '4.6', 'Ependymal cell': '6.7', 'Oligodendrocyte': '5.5', 'Oligodendrocyte precursor cell': '6.0', 'Endothelial cell': '1.4', 'Pericyte': '2.8', 'Vascular associated smooth muscle cell': '2.3', 'Fibroblast': '3.0', 'Leukocyte': '3.0', 'Basophil': '0.1', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.1', 'Non-classical monocyte': '1.5', 'Intermediate monocyte': '0.1', 'T-reg': '1.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.1', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.3', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.1', 'Naive B-cell': '1.9', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '1.5', 'Total PBMC': '0.4', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell TFH': '0.4', 'Memory CD4 T-cell Th2': '0.6', 'Memory CD4 T-cell Th17': '0.6', 'Memory CD4 T-cell Th1\\/Th17': '0.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.9', 'Terminal effector memory CD4 T-cell': '0.5', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '1.1', 'Terminal effector memory CD8 T-cell': '0.1', 'Switched memory B-cell': '1.1', 'Plasmablast': '4.1', 'Non-switched memory B-cell': '1.2', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '0.1', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.3', 'Memory T-reg': '2.3', 'Naive T-reg': '0.5'}
|
4BN2, 6ZPH, 6ZPI, 7RYP
|
{'Adipose Tissue': 0.5448089036544851, 'Adrenal Gland': 0.3842305813953488, 'Bladder': 0.5918952380952381, 'Blood': 4.854553104413348, 'Blood Vessel': 0.4357964644194756, 'Brain': 0.6074563815291446, 'Breast': 0.4807554030501089, 'Cervix Uteri': 0.8412157894736843, 'Colon': 1.3200356611039796, 'Esophagus': 1.6432444844290657, 'Fallopian Tube': 0.4881111111111111, 'Heart': 0.1988811022067363, 'Kidney': 0.2389267415730337, 'Liver': 0.128901407079646, 'Lung': 0.965648615916955, 'Muscle': 0.1264767708592777, 'Nerve': 0.5977012924071082, 'Ovary': 0.4638607222222222, 'Pancreas': 0.1391602408536585, 'Pituitary': 0.4059791166077738, 'Prostate': 0.5926855102040817, 'Salivary Gland': 0.7092278395061729, 'Skin': 3.895280099502488, 'Small Intestine': 1.9810529411764708, 'Spleen': 1.877571369294606, 'Stomach': 0.9108428969359332, 'Testis': 22.425326869806092, 'Thyroid': 0.3939495865237366, 'Uterus': 0.6966091549295774, 'Vagina': 1.7094839743589745}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
|
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1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.95, 0.97, 0.96, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 0.97, 0.9, 0.72, 0.95, 0.79, 0.51, 0.83, 0.81, 0.38, 0.65, 0.77, 0.55, 0.65, 0.55, 0.57, 0.66, 0.64, 0.53, 0.41, 0.51, 0.68, 0.6, 0.6, 0.65, 0.58, 0.52, 0.59, 0.55, 0.61, 0.67, 0.55, 0.48, 0.62, 0.49, 0.6, 0.68, 0.42, 0.57, 0.6, 0.71, 0.61, 0.52, 0.6, 0.65, 0.43, 0.45, 0.65, 0.67, 0.57, 0.65, 0.65, 0.45, 0.5, 0.56, 0.54, 0.56, 0.69, 0.7, 0.48, 0.42, 0.56, 0.54, 0.6, 0.64, 0.57, 0.64, 0.48, 0.69, 0.58, 0.55, 0.67, 0.61, 0.57, 0.48, 0.53, 0.53, 0.57, 0.58, 0.56, 0.57, 0.65, 0.59, 0.55, 0.56, 0.6, 0.43, 0.57, 0.5, 0.58, 0.6, 0.52, 0.49, 0.65, 0.56, 0.54, 0.42, 0.48, 0.53, 0.6, 0.57, 0.56, 0.67, 0.54, 0.65, 0.63, 0.7, 0.43, 0.48, 0.51, 0.76, 0.57, 0.49, 0.51, 0.43, 0.58, 0.54, 0.7, 0.57, 0.67, 0.48, 0.43, 0.6, 0.47, 0.45, 0.46, 0.58, 0.41, 0.56, 0.53, 0.68, 0.55, 0.45, 0.63, 0.45, 0.63, 0.66, 0.63, 0.64, 0.56, 0.6, 0.5, 0.57, 0.47, 0.5, 0.38, 0.58, 0.57, 0.53, 0.47, 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0.5, 0.71, 0.52, 0.49, 0.59, 0.57, 0.43, 0.65, 0.73, 0.51, 0.6, 0.55, 0.55, 0.54, 0.51, 0.66, 0.56, 0.66, 0.59, 0.43, 0.73, 0.83, 0.75, 0.68, 0.76]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 71.929215
| 0.536635
| 239
|
O43255
|
Q9P212
|
22199232, E3Net
|
UbiNet, UbiBrowser, 31181401
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
PLCE1
|
MTSEEMTASVLIPVTQRKVVSAQSAADESSEKVSDINISKAHTVRRSGETSHTISQLNKLKEEPSGSNLPKILSIAREKIVSDENSNEKCWEKIMPDSAKNLNINCNNILRNHQHGLPQRQFYEMYNSVAEEDLCLETGIPSPLERKVFPGIQLELDRPSMGISPLGNQSVIIETGRAHPDSRRAVFHFHYEVDRRMSDTFCTLSENLILDDCGNCVPLPGGEEKQKKNYVAYTCKLMELAKNCDNKNEQLQCDHCDTLNDKYFCFEGSCEKVDMVYSGDSFCRKDFTDSQAAKTFLSHFEDFPDNCDDVEEDAFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLTAWSYIDQKRNGPLLPCGRVMEPPSTVEIRQDGSQRLSEAQWYPIYNAVRREETENTVGSLLHFLTKLPASETAHGRISVGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARSGLLSTFGGSTGRMMLKERQPGPSVANSNALPSSSAGISKELIDLQPLIQFPEEVASILMEQEQTIYRRVLPVDYLCFLTRDLGTPECQSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCNRSLETDEEDSPSEGNSSRKSSLKDKSRWQFIIGDLLDSDNDIFEQSKEYDSHGSEDSQKAFDHGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTASPASSKAKLGVLNNTAEPGKFPLLGNAGLSSLTEGVLDLFAVKAVYMGHPGIDIHTVCVQNKLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQQWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGTSAKNAEKPNMQRNNTLGISTTKKKKKILMRGESGEVTDDEMATRKAKMHKECRSRSGSDPQDINEQEESEVNAIANPPNPLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGMKGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRSGSESAPLYTNLTIDENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQAYNGGNANPRPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPLNPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTIVSGQNVCPSNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFHVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSRRMEENSSGNTMSASSMFNTEERKCLQTHRVTVHGVPGPEPFTVFTINGGTKAKQLLQQILTNEQDIKPVTTDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIMQILSSWFPEEGYMGRIVLKTQQENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKTTTPKSSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQPRGLTSPSQLLTSESIQTKEEKPVGGLSSSDTMDYRQ
|
Homo sapiens
|
Cytoplasm, cytosol, Cell membrane, Golgi apparatus membrane, Cell projection, lamellipodium
|
Low tissue specificity
|
{'Ciliated cells': '21.4', 'Basal respiratory cells': '6.8', 'Club cells': '22.0', 'Ionocytes': '8.8', 'Mucus glandular cells': '22.7', 'Serous glandular cells': '11.3', 'Gastric mucus-secreting cells': '24.2', 'Proximal enterocytes': '8.4', 'Paneth cells': '34.6', 'Distal enterocytes': '90.3', 'Intestinal goblet cells': '8.1', 'Exocrine glandular cells': '0.372', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '3.3', 'Breast glandular cells': '0.156', 'Breast myoepithelial cells': '0.258', 'Glandular and luminal cells': '10.0', 'Secretory cells': '9.5', 'Basal keratinocytes': '5.1', 'Suprabasal keratinocytes': '4.1', 'Basal squamous epithelial cells': '2.4', 'Squamous epithelial cells': '1.7', 'Alveolar cells type 1': '0.333', 'Alveolar cells type 2': '-0.513', 'Salivary duct cells': '15.8', 'Ductal cells': '0.018', 'Hepatocytes': '0.038', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.252', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.500', 'Sertoli cells': '-0.250', 'Granulosa cells': '2.9', 'Enteroendocrine cells': '18.0', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '-0.122', 'Excitatory neurons': '3.0', 'Inhibitory neurons': '80.5', 'Cone photoreceptor cells': '3.4', 'Rod photoreceptor cells': '16.0', 'Bipolar cells': '9.8', 'Horizontal cells': '13.8', 'Astrocytes': '66.0', 'Oligodendrocyte precursor cells': '115.6', 'Oligodendrocytes': '2.3', 'Microglial cells': '5.4', 'Muller glia cells': '70.1', 'Schwann cells': '0.519', 'Spermatogonia': '-0.070', 'Spermatocytes': '0.044', 'Early spermatids': '0.257', 'Late spermatids': '0.106', 'Oocytes': '2.9', 'Cytotrophoblasts': '3.5', 'Syncytiotrophoblasts': '2.2', 'Extravillous trophoblasts': '2.6', 'Endothelial cells': '9.8', 'Lymphatic endothelial cells': '42.7', 'Cardiomyocytes': '0.495', 'Skeletal myocytes': '-0.096', 'Smooth muscle cells': '38.1', 'Adipocytes': '9.1', 'Melanocytes': '-0.174', 'Fibroblasts': '12.1', 'Peritubular cells': '0.109', 'Endometrial stromal cells': '19.6', 'Ovarian stromal cells': '14.8', 'Undifferentiated cells': '21.8', 'T-cells': '3.3', 'B-cells': '5.8', 'Plasma cells': '2.3', 'Nk-cells': '3.2', 'Granulocytes': '3.0', 'Monocytes': '0.4', 'Macrophages': '2.0', 'Hofbauer cells': '0.9', 'Kupffer cells': '3.8', 'Dendritic cells': '2.2', 'Langerhans cells': '-0.098', 'Erythroid cells': '0.058', 'Adipocytes (Subcutaneous)': '-0.045', 'Adipocytes (Visceral)': '-0.170', 'Breast glandular cells (progenitors)': '-0.015', 'Adipocytes (Breast)': '-0.173', 'Colon enterocytes': '0.136', 'Colon enteroendocrine cells': '0.247', 'Enteric glia cells': '0.550', 'Mitotic cells (Colon)': '0.139', 'Mitotic cells (Heart)': '0.438', 'Podocytes': '0.852', 'Ascending Loop of Henle cells': '-0.086', 'Intercalated cells': '0.448', 'Cholangiocyte': '0.358', 'NK-cells (Liver)': '0.024', 'Respiratory ciliated cells': '0.142', 'Mitotic cells (Lung)': '-0.256', 'NK-cells (Lung)': '0.461', 'B-cells (Lung)': '0.180', 'Alpha cells': '0.119', 'Beta cells': '0.094', 'Prostate glandular cells': '-0.503', 'Prostate basal glandular cells': '-0.228', 'Urothelial cells': '-0.031', 'Keratinocyte (other)': '-0.539', 'Keratinocyte (granular)': '-0.359', 'Hair cortex cells': '0.323', 'Inner root sheath cells': '0.367', 'Outer root sheath cells': '0.485', 'Sebaceous gland cells': '0.241', 'Eccrine sweat gland cells': '0.516', 'Adipocytes (Skin)': '0.488', 'Mitotic cells (Skin)': '0.112', 'Parietal cells': '-0.558', 'Chief cells': '-0.702', 'Gastric mucous cells': '-0.339', 'Gastric enteroendocrine cells': '-0.523', 'Mitotic cells (Stomach)': '-0.011', 'Parafollicular cells': '-0.012', 'Thyroid glandular cells': '0.348', 'Mitotic cells (Thyroid)': '-0.105', 'Adrenal cortex cells': '0.315', 'Adrenal medulla cells': '0.346', 'Mitotic cells (Adrenal gland)': '0.103', 'Minor salivary glandular cells': '0.564', 'Minor salivary gland ductal cells': '0.366', 'Minor salivary gland basal cells': '-0.075', 'Mitotic cells (Minor salivary gland)': '0.099', 'Adipocytes (Minor salivary gland)': '0.160', 'Somatotropes': '-0.259', 'Lactotropes': '-0.368', 'Gonadotropes': '-0.063', 'Corticotropes': '-0.249', 'Thyrotropes': '-0.059', 'Undifferentiated cells (Pituitary gland)': '0.496', 'Mitotic cells (Spleen)': '-0.188', 'Platelets': '-0.136', 'Erythrocytes': '0.005', 'Hematopoietic stem cells': '-0.254', 'B-cells (Spleen)': '0.167', 'NK-cells (Spleen)': '0.295', 'Amygdala excitatory': '20.8', 'Cerebellar inhibitory': '17.6', 'Cge interneuron': '71.0', 'Deep-layer corticothalamic and 6b': '21.9', 'Deep-layer intratelencephalic': '8.4', 'Deep-layer near-projecting': '8.8', 'Eccentric medium spiny neuron': '15.6', 'Hippocampal ca1-3': '9.2', 'Hippocampal ca4': '17.7', 'Hippocampal dentate gyrus': '8.5', 'Lamp5-lhx6 and chandelier': '46.8', 'Lower rhombic lip': '13.5', 'Mammillary body': '8.0', 'Medium spiny neuron': '11.7', 'Mge interneuron': '124.3', 'Midbrain-derived inhibitory': '93.6', 'Miscellaneous': '9.7', 'Splatter': '41.6', 'Thalamic excitatory': '12.6', 'Upper rhombic lip': '10.5', 'Upper-layer intratelencephalic': '5.4', 'Astrocyte': '182.4', 'Bergmann glia': '34.1', 'Central nervous system macrophage': '7.3', 'Choroid plexus epithelial cell': '294.5', 'Committed oligodendrocyte precursor': '117.9', 'Ependymal cell': '294.3', 'Oligodendrocyte': '5.8', 'Oligodendrocyte precursor cell': '209.8', 'Endothelial cell': '15.1', 'Pericyte': '715.0', 'Vascular associated smooth muscle cell': '658.7', 'Fibroblast': '119.5', 'Leukocyte': '3.6', 'Basophil': '1.4', 'Eosinophil': '0.0', 'Neutrophil': '1.4', 'Classical monocyte': '0.3', 'Non-classical monocyte': '0.7', 'Intermediate monocyte': '1.0', 'T-reg': '2.0', 'GdT-cell': '0.2', 'MAIT T-cell': '1.6', 'Memory CD4 T-cell': '0.2', 'Naive CD4 T-cell': '2.1', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '1.9', 'Memory B-cell': '0.3', 'Naive B-cell': '5.6', 'Plasmacytoid DC': '2.1', 'Myeloid DC': '0.9', 'NK-cell': '0.8', 'Total PBMC': '1.0', 'Vd2 gdTCR': '1.3', 'Memory CD4 T-cell Th1\\/Th17': '1.1', 'Memory CD4 T-cell Th17': '1.1', 'Memory CD4 T-cell Th2': '1.1', 'Non-Vd2 gdTCR': '1.6', 'Memory CD4 T-cell Th1': '1.0', 'Memory CD4 T-cell TFH': '1.2', 'Terminal effector memory CD4 T-cell': '1.7', 'Central memory CD8 T-cell': '2.2', 'Effector memory CD8 T-cell': '1.1', 'Terminal effector memory CD8 T-cell': '1.3', 'Non-switched memory B-cell': '3.0', 'Plasmablast': '1.6', 'Switched memory B-cell': '2.9', 'Exhausted memory B-cell': '4.1', 'Progenitor cell': '1.7', 'Memory T-reg': '1.1', 'Naive CD4 T-cell activated': '7.2', 'Naive CD8 T-cell activated': '5.4', 'Naive T-reg': '2.5'}
|
2BYE, 2BYF, 2C5L
|
{'Adipose Tissue': 4.712897840531562, 'Adrenal Gland': 1.851624031007752, 'Bladder': 8.706047619047618, 'Blood': 0.2233873186221743, 'Blood Vessel': 18.307967041198506, 'Brain': 2.4025807721423167, 'Breast': 4.004116557734204, 'Cervix Uteri': 12.194947368421053, 'Colon': 10.769512195121951, 'Esophagus': 7.993115294117647, 'Fallopian Tube': 7.762999999999999, 'Heart': 5.599760162601626, 'Kidney': 5.830606741573034, 'Liver': 0.5237548672566372, 'Lung': 10.703846020761246, 'Muscle': 2.6069037359900373, 'Nerve': 17.61552180936995, 'Ovary': 6.830222222222223, 'Pancreas': 3.0969993902439024, 'Pituitary': 6.523187279151943, 'Prostate': 5.862502040816327, 'Salivary Gland': 2.806935185185185, 'Skin': 2.121210447761194, 'Small Intestine': 6.344887700534759, 'Spleen': 8.691929460580914, 'Stomach': 8.848908077994428, 'Testis': 3.983390581717451, 'Thyroid': 15.681681470137828, 'Uterus': 15.700718309859155, 'Vagina': 8.743538461538462}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.96, 0.97, 0.96, 0.94, 0.93, 0.95, 0.93, 0.87, 0.9, 0.93, 0.89, 0.91, 0.93, 0.93, 0.91, 0.92, 0.47, 0.44, 0.4, 0.11, 0.06, 0.41, 0.17, 0.75, 0.43, 0.95, 0.92, 1.0, 0.99, 0.98, 0.93, 0.97, 0.94, 0.92, 0.94, 0.92, 0.86, 0.9, 0.9, 0.94, 0.94, 0.9, 1.0, 0.94, 0.96, 0.98, 0.91, 0.91, 0.88, 0.75, 0.95, 0.65, 0.57, 0.71, 0.73, 0.23, 0.69, 0.65, 0.49, 0.03, 0.42, 0.65, 0.01, 0.46, 0.01, 0.41, 0.41, 0.47, 0.68, 0.4, 0.23, 0.0, 0.22, 0.35, 0.34, 0.0, 0.08, 0.23, 0.03, 0.65, 0.61, 0.42, 0.3, 0.13, 0.02, 0.12, 0.4, 0.74, 0.11, 0.22, 0.75, 0.85, 0.29, 0.85, 0.48, 0.02, 0.43, 0.57, 0.45, 0.82, 0.34, 0.48, 0.02, 0.73, 0.68, 0.51, 0.29, 0.53, 0.15, 0.57, 0.61, 0.22, 0.13, 0.74, 0.43, 0.0, 0.49, 0.78, 0.09, 0.34, 0.0, 0.24, 0.02, 0.52, 0.17, 0.42, 0.92, 0.55, 0.45, 0.07, 0.77, 0.49, 0.37, 0.18, 0.35, 0.19, 0.73, 0.5, 0.02, 0.47, 0.7, 0.16, 0.08, 0.6, 0.62, 0.02, 0.67, 0.45, 0.31, 0.45, 0.09, 0.42, 0.15, 0.13, 0.08, 0.11, 0.43, 0.34, 0.78, 0.31, 0.87, 0.25, 0.67, 0.23, 0.49, 0.22, 0.81, 0.36, 0.0, 0.19, 0.44, 0.12, 0.06, 0.73, 0.7, 0.68, 0.14, 0.76, 0.63, 0.14, 0.26, 0.51, 0.19, 0.74, 0.3, 0.5, 0.75, 0.09, 0.38, 0.02, 0.22, 0.0, 0.23, 0.54, 0.02, 0.62, 0.45, 0.89, 0.37, 0.54, 0.04, 0.09, 0.0, 0.0, 0.0, 0.04, 0.0, 0.06, 0.12, 0.45, 0.92, 0.25, 0.31, 0.0, 0.0, 0.01, 0.01, 0.0, 0.18, 0.01, 0.3, 0.5, 0.52, 0.78, 0.9, 0.76, 0.6, 0.26, 0.26, 0.01, 0.01, 0.02, 0.03, 0.0, 0.01, 0.0, 0.1, 0.0, 0.35, 0.26, 0.76, 0.32, 0.03, 0.65, 0.54, 0.06, 0.25, 0.04, 0.35, 0.04, 0.17, 0.0, 0.43, 0.34, 0.77, 0.98, 0.52, 0.73, 0.3, 0.46, 0.29, 0.65, 0.25, 0.56, 0.06, 0.29, 0.02, 0.07, 0.18, 0.42, 0.31, 0.16, 0.69, 0.42, 0.01, 0.08, 0.82, 0.74, 0.43, 0.39, 0.04, 0.04, 0.34, 0.03, 0.47, 0.28, 0.6, 0.32, 0.01, 0.51, 0.54, 0.13, 0.26, 0.76, 0.89, 0.19, 0.31, 0.0, 0.29, 0.0, 0.35, 0.0, 0.2, 0.02, 0.45, 0.55, 0.38, 0.93, 0.95]
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0.14, 0.15, 0.22, 0.05, 0.07, 0.08, 0.33, 0.57, 0.14, 0.14, 0.16, 0.02, 0.21, 0.01, 0.08, 0.09, 0.36, 0.63, 0.6, 0.81, 0.79, 0.81, 0.77, 0.95, 0.94, 0.97, 0.97, 0.95, 0.97, 0.97, 1.0, 0.99, 0.97, 0.96, 0.75, 0.96, 0.8, 0.93, 0.78, 0.82, 0.84, 0.52, 0.39, 0.11, 0.65, 0.0, 0.42, 0.0, 0.27, 0.56, 0.06, 0.1, 0.84, 0.62, 0.33, 0.53, 0.72, 0.05, 0.43, 0.07, 0.58, 0.0, 0.49, 0.34, 0.76, 0.07, 0.18, 0.01, 0.25, 0.38, 0.01, 0.02, 0.53, 0.31, 0.0, 0.08, 0.51, 0.45, 0.03, 0.59, 0.9, 0.04, 0.76, 0.41, 0.06, 0.6, 0.72, 0.35, 0.67, 0.45, 0.24, 0.52, 0.35, 0.07, 0.1, 0.01, 0.07, 0.1, 0.16, 0.17, 0.34, 0.74, 0.68, 0.78, 0.91, 0.9, 1.0, 0.97, 1.0, 0.96, 0.91, 0.79, 0.83, 0.41, 0.55, 0.57, 0.43, 0.45, 0.04, 0.7, 0.44, 0.82, 0.17, 0.2, 0.0, 0.37, 0.57, 0.01, 0.32, 0.67, 0.63, 0.21, 0.86, 0.36, 0.6, 0.39, 0.32, 0.01, 0.03, 0.03, 0.34, 0.22, 0.39, 0.7, 0.58, 0.17, 0.63, 0.39, 0.55, 0.83, 0.75, 0.7, 0.86, 0.92, 0.92, 1.0, 1.0, 0.94, 0.9, 0.93, 0.71, 0.78, 0.95, 0.89, 0.78, 0.95, 0.73, 0.92, 0.61, 0.75, 0.75, 0.56, 0.56, 0.88, 0.6, 0.89, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 0.97, 1.0, 0.98]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 59.459474
| 0.567819
| 75
|
O43255
|
Q9UHB7
| null |
degron_data
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
AFF4
|
MNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMKDFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASIMTDLVRYTRQGLHWLRQDAKLIS
|
Homo sapiens
|
Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '73.5', 'Basal respiratory cells': '51.4', 'Club cells': '76.4', 'Ionocytes': '71.8', 'Mucus glandular cells': '156.6', 'Serous glandular cells': '67.2', 'Gastric mucus-secreting cells': '190.4', 'Proximal enterocytes': '46.0', 'Paneth cells': '54.6', 'Distal enterocytes': '61.8', 'Intestinal goblet cells': '58.8', 'Exocrine glandular cells': '-0.546', 'Basal prostatic cells': '96.7', 'Prostatic glandular cells': '98.8', 'Breast glandular cells': '0.493', 'Breast myoepithelial cells': '0.592', 'Glandular and luminal cells': '185.0', 'Secretory cells': '63.6', 'Basal keratinocytes': '81.1', 'Suprabasal keratinocytes': '99.0', 'Basal squamous epithelial cells': '126.8', 'Squamous epithelial cells': '126.7', 'Alveolar cells type 1': '0.242', 'Alveolar cells type 2': '-0.247', 'Salivary duct cells': '143.3', 'Ductal cells': '0.577', 'Hepatocytes': '0.071', 'Cholangiocytes': '45.8', 'Proximal tubular cells': '0.252', 'Distal tubular cells': '9.2', 'Collecting duct cells': '56.4', 'Mesothelial cells': '0.286', 'Sertoli cells': '0.356', 'Granulosa cells': '119.5', 'Enteroendocrine cells': '47.6', 'Pancreatic endocrine cells': '40.8', 'Leydig cells': '0.357', 'Excitatory neurons': '96.2', 'Inhibitory neurons': '81.5', 'Cone photoreceptor cells': '49.3', 'Rod photoreceptor cells': '134.4', 'Bipolar cells': '73.5', 'Horizontal cells': '75.5', 'Astrocytes': '59.1', 'Oligodendrocyte precursor cells': '69.3', 'Oligodendrocytes': '98.7', 'Microglial cells': '58.2', 'Muller glia cells': '53.5', 'Schwann cells': '0.067', 'Spermatogonia': '0.318', 'Spermatocytes': '0.283', 'Early spermatids': '-0.050', 'Late spermatids': '-0.305', 'Oocytes': '14.0', 'Cytotrophoblasts': '35.2', 'Syncytiotrophoblasts': '75.4', 'Extravillous trophoblasts': '51.3', 'Endothelial cells': '79.6', 'Lymphatic endothelial cells': '62.9', 'Cardiomyocytes': '0.508', 'Skeletal myocytes': '-0.146', 'Smooth muscle cells': '91.1', 'Adipocytes': '127.9', 'Melanocytes': '0.181', 'Fibroblasts': '89.6', 'Peritubular cells': '0.370', 'Endometrial stromal cells': '132.1', 'Ovarian stromal cells': '97.1', 'Undifferentiated cells': '30.3', 'T-cells': '69.9', 'B-cells': '101.7', 'Plasma cells': '75.6', 'Nk-cells': '67.3', 'Granulocytes': '81.5', 'Monocytes': '157.4', 'Macrophages': '113.3', 'Hofbauer cells': '46.2', 'Kupffer cells': '56.9', 'Dendritic cells': '141.3', 'Langerhans cells': '0.074', 'Erythroid cells': '0.105', 'Adipocytes (Subcutaneous)': '-0.289', 'Adipocytes (Visceral)': '-0.300', 'Breast glandular cells (progenitors)': '0.343', 'Adipocytes (Breast)': '-0.549', 'Colon enterocytes': '-0.145', 'Colon enteroendocrine cells': '0.269', 'Enteric glia cells': '-0.028', 'Mitotic cells (Colon)': '-0.022', 'Mitotic cells (Heart)': '0.494', 'Podocytes': '-0.001', 'Ascending Loop of Henle cells': '0.359', 'Intercalated cells': '0.009', 'Cholangiocyte': '0.238', 'NK-cells (Liver)': '-0.114', 'Respiratory ciliated cells': '0.033', 'Mitotic cells (Lung)': '-0.180', 'NK-cells (Lung)': '0.377', 'B-cells (Lung)': '0.197', 'Alpha cells': '0.378', 'Beta cells': '0.245', 'Prostate glandular cells': '-0.053', 'Prostate basal glandular cells': '0.081', 'Urothelial cells': '0.098', 'Keratinocyte (other)': '0.195', 'Keratinocyte (granular)': '-0.167', 'Hair cortex cells': '-0.011', 'Inner root sheath cells': '0.089', 'Outer root sheath cells': '0.241', 'Sebaceous gland cells': '-0.027', 'Eccrine sweat gland cells': '0.055', 'Adipocytes (Skin)': '-0.177', 'Mitotic cells (Skin)': '0.310', 'Parietal cells': '-0.555', 'Chief cells': '-0.525', 'Gastric mucous cells': '-0.290', 'Gastric enteroendocrine cells': '-0.384', 'Mitotic cells (Stomach)': '0.009', 'Parafollicular cells': '0.148', 'Thyroid glandular cells': '0.333', 'Mitotic cells (Thyroid)': '-0.047', 'Adrenal cortex cells': '0.471', 'Adrenal medulla cells': '0.051', 'Mitotic cells (Adrenal gland)': '0.035', 'Minor salivary glandular cells': '0.406', 'Minor salivary gland ductal cells': '0.189', 'Minor salivary gland basal cells': '0.423', 'Mitotic cells (Minor salivary gland)': '0.332', 'Adipocytes (Minor salivary gland)': '0.095', 'Somatotropes': '0.024', 'Lactotropes': '-0.132', 'Gonadotropes': '0.007', 'Corticotropes': '-0.087', 'Thyrotropes': '0.005', 'Undifferentiated cells (Pituitary gland)': '0.053', 'Mitotic cells (Spleen)': '-0.204', 'Platelets': '-0.162', 'Erythrocytes': '-0.146', 'Hematopoietic stem cells': '-0.286', 'B-cells (Spleen)': '0.263', 'NK-cells (Spleen)': '0.276', 'Amygdala excitatory': '176.7', 'Cerebellar inhibitory': '125.1', 'Cge interneuron': '146.7', 'Deep-layer corticothalamic and 6b': '165.3', 'Deep-layer intratelencephalic': '182.0', 'Deep-layer near-projecting': '166.2', 'Eccentric medium spiny neuron': '190.1', 'Hippocampal ca1-3': '173.9', 'Hippocampal ca4': '173.1', 'Hippocampal dentate gyrus': '191.2', 'Lamp5-lhx6 and chandelier': '145.8', 'Lower rhombic lip': '159.2', 'Mammillary body': '174.3', 'Medium spiny neuron': '218.5', 'Mge interneuron': '154.3', 'Midbrain-derived inhibitory': '155.0', 'Miscellaneous': '169.0', 'Splatter': '154.4', 'Thalamic excitatory': '159.7', 'Upper rhombic lip': '170.9', 'Upper-layer intratelencephalic': '187.1', 'Astrocyte': '160.2', 'Bergmann glia': '156.6', 'Central nervous system macrophage': '181.4', 'Choroid plexus epithelial cell': '184.8', 'Committed oligodendrocyte precursor': '186.5', 'Ependymal cell': '138.3', 'Oligodendrocyte': '184.6', 'Oligodendrocyte precursor cell': '145.7', 'Endothelial cell': '307.0', 'Pericyte': '170.8', 'Vascular associated smooth muscle cell': '201.5', 'Fibroblast': '257.2', 'Leukocyte': '145.8', 'Basophil': '57.9', 'Eosinophil': '3.2', 'Neutrophil': '28.8', 'Classical monocyte': '55.8', 'Non-classical monocyte': '69.6', 'Intermediate monocyte': '33.1', 'T-reg': '45.3', 'GdT-cell': '4.0', 'MAIT T-cell': '46.0', 'Memory CD4 T-cell': '3.7', 'Naive CD4 T-cell': '104.5', 'Memory CD8 T-cell': '2.8', 'Naive CD8 T-cell': '86.9', 'Memory B-cell': '6.2', 'Naive B-cell': '180.2', 'Plasmacytoid DC': '43.5', 'Myeloid DC': '27.5', 'NK-cell': '81.1', 'Total PBMC': '27.2', 'Vd2 gdTCR': '38.4', 'Memory CD4 T-cell Th1\\/Th17': '96.1', 'Memory CD4 T-cell Th17': '77.4', 'Memory CD4 T-cell Th2': '93.8', 'Non-Vd2 gdTCR': '46.5', 'Memory CD4 T-cell Th1': '82.5', 'Memory CD4 T-cell TFH': '75.1', 'Terminal effector memory CD4 T-cell': '35.3', 'Central memory CD8 T-cell': '64.2', 'Effector memory CD8 T-cell': '32.7', 'Terminal effector memory CD8 T-cell': '41.2', 'Non-switched memory B-cell': '51.5', 'Plasmablast': '25.8', 'Switched memory B-cell': '43.6', 'Exhausted memory B-cell': '36.4', 'Progenitor cell': '22.2', 'Memory T-reg': '58.5', 'Naive CD4 T-cell activated': '102.6', 'Naive CD8 T-cell activated': '76.0', 'Naive T-reg': '104.7'}
|
4IMY, 4OGR, 4OR5, 5JW9, 5L1Z, 6CYT, 6K7P, 6KN5, 6R80
|
{'Adipose Tissue': 33.18610215946844, 'Adrenal Gland': 28.371445736434108, 'Bladder': 35.739999999999995, 'Blood': 8.910976856835308, 'Blood Vessel': 47.83754456928839, 'Brain': 16.614344436033306, 'Breast': 34.25124183006536, 'Cervix Uteri': 41.333684210526314, 'Colon': 28.091801026957636, 'Esophagus': 31.10711972318339, 'Fallopian Tube': 37.721111111111114, 'Heart': 11.714525319396053, 'Kidney': 14.269629213483148, 'Liver': 14.672, 'Lung': 40.90517301038062, 'Muscle': 19.87926400996264, 'Nerve': 39.24725363489499, 'Ovary': 52.300444444444445, 'Pancreas': 9.979213414634144, 'Pituitary': 38.21795053003534, 'Prostate': 33.07187755102041, 'Salivary Gland': 29.67037037037037, 'Skin': 35.856005527915976, 'Small Intestine': 23.33651336898396, 'Spleen': 18.267564315352697, 'Stomach': 23.06971866295265, 'Testis': 28.642022160664823, 'Thyroid': 41.08807044410413, 'Uterus': 44.86288732394366, 'Vagina': 39.03532051282051}
|
[42.87, 46.62, 46.12, 55.69, 49.35, 49.86, 49.82, 49.71, 48.25, 47.48, 48.54, 44.15, 47.57, 40.86, 34.13, 45.63, 43.4, 47.8, 54.15, 56.68, 51.19, 45.2, 47.19, 40.28, 40.63, 38.3, 38.97, 33.38, 45.75, 52.83, 62.18, 66.74, 77.63, 82.02, 83.84, 83.47, 82.46, 75.31, 58.47, 48.94, 37.89, 36.91, 35.46, 33.52, 30.65, 32.5, 28.94, 32.64, 31.53, 27.87, 32.07, 32.85, 29.96, 34.37, 35.17, 39.3, 38.73, 34.99, 36.99, 35.87, 32.74, 38.51, 37.06, 45.5, 48.76, 53.18, 56.23, 62.71, 68.14, 71.31, 79.13, 81.25, 82.37, 89.41, 91.71, 91.56, 92.59, 95.45, 94.9, 95.59, 94.94, 95.28, 93.99, 92.61, 92.79, 94.6, 95.46, 94.62, 94.43, 93.78, 94.14, 95.45, 95.48, 95.82, 94.34, 95.21, 94.51, 96.03, 95.98, 95.09, 94.65, 92.72, 93.14, 95.14, 93.7, 92.25, 93.99, 93.91, 92.81, 95.69, 96.45, 95.32, 95.9, 97.15, 96.0, 94.02, 93.58, 93.21, 91.53, 91.5, 90.53, 94.88, 95.93, 95.64, 96.18, 95.36, 95.07, 95.67, 95.08, 94.42, 95.18, 94.18, 92.59, 94.22, 95.29, 95.92, 96.1, 96.0, 93.76, 94.36, 94.18, 91.57, 91.48, 93.76, 94.89, 95.75, 95.99, 96.18, 96.63, 96.39, 95.0, 95.52, 96.26, 95.66, 93.34, 94.37, 95.82, 94.44, 89.88, 89.84, 92.89, 89.73, 91.86, 93.12, 93.76, 93.71, 92.94, 94.82, 93.55, 89.31, 81.71, 69.69, 65.44, 82.77, 92.31, 92.94, 95.77, 94.53, 94.4, 93.45, 94.0, 94.45, 96.16, 96.38, 95.28, 96.17, 96.65, 95.0, 92.77, 93.88, 94.24, 93.49, 90.47, 90.63, 92.93, 93.27, 95.5, 96.92, 97.62, 97.63, 97.75, 97.9, 98.17, 97.86, 97.67, 97.39, 97.14, 95.8, 95.2, 95.84, 93.29, 92.49, 89.76, 88.43, 90.28, 92.39, 93.25, 95.73, 96.2, 96.32, 97.29, 98.05, 98.14, 98.23, 97.35, 96.37, 97.7, 98.09, 98.3, 97.68, 97.84, 97.11, 97.22, 95.6, 95.16, 91.97, 88.18, 79.07, 80.77, 79.47, 77.81, 86.19, 92.22, 95.11, 97.24, 97.4, 98.18, 97.84, 98.21, 97.88, 97.95, 97.31, 95.49, 93.47, 92.92, 93.0, 95.19, 96.38, 95.84, 97.15, 98.32, 98.47, 98.6, 98.71, 98.75, 98.63, 98.47, 96.5, 94.0, 92.73, 95.87, 96.81, 97.83, 98.25, 98.46, 98.59, 98.45, 98.02, 97.64, 97.83, 95.5, 95.45, 94.9, 90.93, 89.2, 88.38, 91.39, 90.2, 89.63, 92.47, 92.81, 92.26, 94.61, 94.84, 96.68, 97.89, 98.31, 97.76, 97.37, 95.61, 94.23, 94.59, 96.34, 96.77, 95.42, 96.93, 97.69, 96.84, 95.1, 93.01, 94.16, 96.53, 97.78, 97.5, 98.45, 98.44, 98.73, 98.68, 98.64, 98.2, 97.12, 89.43, 66.43, 54.73]
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0.92, 0.91, 0.68, 0.85, 0.81, 0.9, 0.8, 0.86, 0.98, 0.88, 0.96, 0.99, 0.94, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.95, 0.95, 0.96, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 0.87, 1.0, 0.83, 1.0, 0.85, 1.0, 0.9, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 1.0, 0.93, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.98, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.84, 1.0, 0.82, 1.0, 0.81, 0.81, 1.0, 0.99, 0.8, 1.0, 0.99, 0.98, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 1.0, 0.93, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 0.99, 0.87, 0.97, 0.93, 0.88, 0.93, 0.9, 0.87, 0.63, 0.73, 0.8, 0.82, 0.54, 0.84, 0.3, 0.44, 0.61, 0.32, 0.95, 0.23, 0.45, 0.68, 0.63, 0.67, 0.35, 0.6, 0.14, 0.52, 0.44, 0.09, 0.23, 0.7, 0.33, 0.0, 0.57, 0.66, 0.15, 0.31, 0.68, 0.39, 0.0, 0.41, 0.78, 0.29, 0.89, 0.51, 0.55, 0.1, 0.31, 0.12, 0.02, 0.01, 0.3, 0.03, 0.0, 0.1, 0.0, 0.0, 0.0, 0.0, 0.12, 0.0, 0.14, 0.01, 0.0, 0.13, 0.1, 0.13, 0.29, 0.54, 0.55, 0.84, 0.94, 0.39, 0.95, 0.51, 0.57, 0.1, 0.23, 0.46, 0.16, 0.0, 0.31, 0.63, 0.02, 0.03, 0.54, 0.14, 0.0, 0.31, 0.49, 0.03, 0.19, 0.54, 0.12, 0.3, 0.48, 0.31, 0.85, 0.31, 0.97, 0.76, 0.23, 0.46, 0.37, 0.24, 0.03, 0.21, 0.18, 0.05, 0.05, 0.01, 0.0, 0.02, 0.04, 0.09, 0.0, 0.03, 0.0, 0.02, 0.0, 0.09, 0.02, 0.33, 0.02, 0.02, 0.21, 0.33, 0.35, 0.27, 0.66, 0.4, 0.0, 0.35, 0.5, 0.25, 0.1, 0.64, 0.33, 0.06, 0.46, 0.63, 0.39, 0.43, 0.69, 0.47, 0.14, 0.62, 0.61, 0.84, 0.48, 0.63, 0.8, 0.82, 0.62, 0.88, 0.86, 0.87, 0.89, 0.88, 0.97, 0.9, 0.99, 0.99, 0.99, 0.97, 0.96, 0.94, 0.92, 0.96, 0.94, 1.0, 1.0, 1.0, 0.99, 0.99, 1.0, 1.0, 0.99, 1.0, 1.0, 0.98, 0.99, 0.8, 0.95, 0.83, 0.78, 0.93, 0.73, 0.92, 0.84, 0.7, 0.93, 0.82, 0.51, 0.84, 0.38, 0.51, 0.71, 0.73, 0.06, 0.58, 0.58, 0.15, 0.29, 0.48, 0.3, 0.14, 0.61, 0.71, 0.07, 0.06, 0.24, 0.14, 0.02, 0.44, 0.46, 0.0, 0.39, 0.45, 0.11, 0.12, 0.61, 0.22, 0.0, 0.34, 0.57, 0.05, 0.12, 0.61, 0.58, 0.15, 0.68, 0.84, 0.06, 0.05, 0.49, 0.35, 0.0, 0.29, 0.71, 0.29, 0.29, 0.5, 0.55, 0.09, 0.52, 0.18, 0.3, 0.68, 0.17, 0.56, 0.07, 0.27, 0.4, 0.0, 0.03, 0.29, 0.05, 0.0, 0.19, 0.0, 0.0, 0.01, 0.19, 0.01, 0.01, 0.18, 0.37, 0.32, 0.4, 0.87, 0.23, 0.87, 0.77]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 53.380688
| 0.809295
| 359
|
O43255
|
Q9Y6H5
|
nan, 17982729
|
degron_data, UbiNet, UbiBrowser
|
SIAH2
|
MSRPSSTGPSANKPCSKQPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAAVISGPGGGGGAGPVSPQHHELTSLFECPVCFDYVLPPILQCQAGHLVCNQCRQKLSCCPTCRGALTPSIRNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHEDICEYRPYSCPCPGASCKWQGSLEAVMSHLMHAHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELNGNRRRLTWEATPRSIHDGVAAAIMNSDCLVFDTAIAHLFADNGNLGINVTISTCCP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '28.2', 'Basal respiratory cells': '12.0', 'Club cells': '30.8', 'Ionocytes': '12.9', 'Mucus glandular cells': '14.0', 'Serous glandular cells': '25.1', 'Gastric mucus-secreting cells': '41.9', 'Proximal enterocytes': '21.3', 'Paneth cells': '19.1', 'Distal enterocytes': '36.4', 'Intestinal goblet cells': '37.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '33.3', 'Prostatic glandular cells': '16.4', 'Breast glandular cells': '0.413', 'Breast myoepithelial cells': '0.207', 'Glandular and luminal cells': '95.3', 'Secretory cells': '19.1', 'Basal keratinocytes': '114.7', 'Suprabasal keratinocytes': '141.7', 'Basal squamous epithelial cells': '152.7', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '-0.042', 'Alveolar cells type 2': '-0.144', 'Salivary duct cells': '17.4', 'Ductal cells': '0.522', 'Hepatocytes': '0.148', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.279', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.309', 'Sertoli cells': '0.530', 'Granulosa cells': '23.7', 'Enteroendocrine cells': '34.8', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.668', 'Excitatory neurons': '13.7', 'Inhibitory neurons': '10.6', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '3.9', 'Bipolar cells': '52.5', 'Horizontal cells': '27.7', 'Astrocytes': '6.5', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '10.7', 'Microglial cells': '13.4', 'Muller glia cells': '29.1', 'Schwann cells': '-0.073', 'Spermatogonia': '0.576', 'Spermatocytes': '-0.016', 'Early spermatids': '-0.546', 'Late spermatids': '-0.652', 'Oocytes': '10.3', 'Cytotrophoblasts': '181.7', 'Syncytiotrophoblasts': '343.0', 'Extravillous trophoblasts': '17.5', 'Endothelial cells': '18.5', 'Lymphatic endothelial cells': '9.5', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.025', 'Smooth muscle cells': '24.1', 'Adipocytes': '16.4', 'Melanocytes': '0.159', 'Fibroblasts': '23.0', 'Peritubular cells': '0.574', 'Endometrial stromal cells': '29.1', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '29.6', 'T-cells': '86.4', 'B-cells': '98.4', 'Plasma cells': '104.4', 'Nk-cells': '50.9', 'Granulocytes': '35.9', 'Monocytes': '129.7', 'Macrophages': '60.5', 'Hofbauer cells': '27.5', 'Kupffer cells': '88.9', 'Dendritic cells': '51.8', 'Langerhans cells': '0.105', 'Erythroid cells': '0.173', 'Adipocytes (Subcutaneous)': '-0.089', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.284', 'Colon enterocytes': '-0.197', 'Colon enteroendocrine cells': '0.110', 'Enteric glia cells': '0.189', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.511', 'Podocytes': '0.040', 'Ascending Loop of Henle cells': '0.343', 'Intercalated cells': '0.145', 'Cholangiocyte': '0.106', 'NK-cells (Liver)': '0.076', 'Respiratory ciliated cells': '0.010', 'Mitotic cells (Lung)': '0.082', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.077', 'Alpha cells': '0.354', 'Beta cells': '0.191', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '-0.139', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.431', 'Keratinocyte (granular)': '0.531', 'Hair cortex cells': '-0.286', 'Inner root sheath cells': '-0.270', 'Outer root sheath cells': '-0.407', 'Sebaceous gland cells': '-0.184', 'Eccrine sweat gland cells': '-0.415', 'Adipocytes (Skin)': '-0.308', 'Mitotic cells (Skin)': '-0.020', 'Parietal cells': '-0.610', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.308', 'Mitotic cells (Stomach)': '-0.015', 'Parafollicular cells': '-0.006', 'Thyroid glandular cells': '0.014', 'Mitotic cells (Thyroid)': '0.158', 'Adrenal cortex cells': '0.359', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '-0.217', 'Minor salivary glandular cells': '-0.100', 'Minor salivary gland ductal cells': '-0.300', 'Minor salivary gland basal cells': '0.662', 'Mitotic cells (Minor salivary gland)': '0.566', 'Adipocytes (Minor salivary gland)': '0.039', 'Somatotropes': '-0.168', 'Lactotropes': '-0.086', 'Gonadotropes': '0.095', 'Corticotropes': '-0.035', 'Thyrotropes': '0.006', 'Undifferentiated cells (Pituitary gland)': '0.092', 'Mitotic cells (Spleen)': '0.020', 'Platelets': '-0.031', 'Erythrocytes': '0.124', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '17.3', 'Cerebellar inhibitory': '12.2', 'Cge interneuron': '15.2', 'Deep-layer corticothalamic and 6b': '20.2', 'Deep-layer intratelencephalic': '22.4', 'Deep-layer near-projecting': '22.8', 'Eccentric medium spiny neuron': '18.7', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '17.1', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '19.2', 'Lower rhombic lip': '24.3', 'Mammillary body': '19.5', 'Medium spiny neuron': '28.1', 'Mge interneuron': '17.8', 'Midbrain-derived inhibitory': '10.8', 'Miscellaneous': '21.1', 'Splatter': '15.2', 'Thalamic excitatory': '21.4', 'Upper rhombic lip': '18.0', 'Upper-layer intratelencephalic': '26.2', 'Astrocyte': '12.1', 'Bergmann glia': '14.7', 'Central nervous system macrophage': '16.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '12.5', 'Ependymal cell': '10.1', 'Oligodendrocyte': '17.6', 'Oligodendrocyte precursor cell': '13.4', 'Endothelial cell': '14.2', 'Pericyte': '18.8', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '15.7', 'Leukocyte': '32.9', 'Basophil': '35.6', 'Eosinophil': '8.6', 'Neutrophil': '33.9', 'Classical monocyte': '61.0', 'Non-classical monocyte': '42.1', 'Intermediate monocyte': '24.4', 'T-reg': '17.4', 'GdT-cell': '1.6', 'MAIT T-cell': '18.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '64.8', 'Memory CD8 T-cell': '2.5', 'Naive CD8 T-cell': '45.1', 'Memory B-cell': '2.2', 'Naive B-cell': '80.6', 'Plasmacytoid DC': '13.3', 'Myeloid DC': '22.0', 'NK-cell': '53.8', 'Total PBMC': '22.0', 'Vd2 gdTCR': '18.5', 'Memory CD4 T-cell Th1\\/Th17': '106.6', 'Memory CD4 T-cell Th17': '125.4', 'Memory CD4 T-cell Th2': '125.5', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '104.1', 'Memory CD4 T-cell TFH': '112.0', 'Terminal effector memory CD4 T-cell': '11.3', 'Central memory CD8 T-cell': '20.7', 'Effector memory CD8 T-cell': '19.2', 'Terminal effector memory CD8 T-cell': '15.5', 'Non-switched memory B-cell': '16.1', 'Plasmablast': '36.2', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '15.9', 'Progenitor cell': '21.2', 'Memory T-reg': '106.1', 'Naive CD4 T-cell activated': '635.5', 'Naive CD8 T-cell activated': '300.3', 'Naive T-reg': '68.7'}
|
5H9M
|
{'Adipose Tissue': 24.233642026578075, 'Adrenal Gland': 94.86872093023256, 'Bladder': 44.45619047619047, 'Blood': 62.09228202368138, 'Blood Vessel': 42.63602247191011, 'Brain': 13.797569265707796, 'Breast': 22.94067320261438, 'Cervix Uteri': 89.54789473684211, 'Colon': 26.17383697047497, 'Esophagus': 41.57795640138408, 'Fallopian Tube': 60.44888888888889, 'Heart': 11.427550522648083, 'Kidney': 13.350932584269662, 'Liver': 39.26938053097345, 'Lung': 26.79690311418685, 'Muscle': 9.20519800747198, 'Nerve': 31.42875605815832, 'Ovary': 50.38505555555555, 'Pancreas': 14.062131097560975, 'Pituitary': 21.051272084805653, 'Prostate': 38.21334693877551, 'Salivary Gland': 23.99285802469136, 'Skin': 44.88580983969043, 'Small Intestine': 21.44326203208556, 'Spleen': 41.326016597510375, 'Stomach': 23.59260445682451, 'Testis': 17.737307479224377, 'Thyroid': 17.004833078101072, 'Uterus': 63.87098591549296, 'Vagina': 76.03621794871795}
|
SNCAIP
|
MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDTQNEDRSVSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPQELGPGDGVGGPPGKSSEPSTSLGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLSGKACSTGSSESSSSNMAPFCVLSPVKSPHLRKASAVIHDQHKLSTEETEISPPLVKCGSAYEPENQSKDFLNKTFSDPHGRKVEKTTPDCQLRAFHLQSSAAESKPEEQVSGLNRTSSQGPEERSEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSLMGEDCLNERNTEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCYGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERQGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQFLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSASSRARPKAKDEDSDKILRQLLGKEISENVCTQEKLSLEFQDAQASSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRPRPQPIVESVESMDSAESLHLMIKKHTLASGGRRFPFSIKASKSLDGHSPSPTSESSEPDLESQYPGSGSIPPNQPSGDPQQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRVTFEEPVVQMEQPSLELNGEKDKDKGRTLQRTSTSNESGDQLKRPFGAFRSIMETLSGNQNNNNNYQAANQLKTSTLPLTSLGRKTDAKGNPASSASKGKNKAA
|
Homo sapiens
|
Cytoplasm
|
Tissue enhanced (cervix, endometrium, ovary)
|
{'Ciliated cells': '7.6', 'Basal respiratory cells': '0.8', 'Club cells': '1.3', 'Ionocytes': '0.7', 'Mucus glandular cells': '0.3', 'Serous glandular cells': '6.8', 'Gastric mucus-secreting cells': '0.6', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.7', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.325', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.362', 'Breast myoepithelial cells': '0.452', 'Glandular and luminal cells': '1.3', 'Secretory cells': '0.4', 'Basal keratinocytes': '3.8', 'Suprabasal keratinocytes': '3.1', 'Basal squamous epithelial cells': '2.0', 'Squamous epithelial cells': '1.6', 'Alveolar cells type 1': '-0.018', 'Alveolar cells type 2': '-0.027', 'Salivary duct cells': '0.5', 'Ductal cells': '0.400', 'Hepatocytes': '0.173', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.113', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.736', 'Sertoli cells': '-0.554', 'Granulosa cells': '0.8', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '-0.537', 'Excitatory neurons': '21.1', 'Inhibitory neurons': '60.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '1.3', 'Astrocytes': '80.2', 'Oligodendrocyte precursor cells': '28.8', 'Oligodendrocytes': '1.8', 'Microglial cells': '12.5', 'Muller glia cells': '0.7', 'Schwann cells': '0.073', 'Spermatogonia': '-0.270', 'Spermatocytes': '0.088', 'Early spermatids': '0.752', 'Late spermatids': '0.660', 'Oocytes': '9.6', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.1', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '11.5', 'Lymphatic endothelial cells': '33.3', 'Cardiomyocytes': '-0.103', 'Skeletal myocytes': '0.288', 'Smooth muscle cells': '4.3', 'Adipocytes': '7.2', 'Melanocytes': '0.174', 'Fibroblasts': '4.0', 'Peritubular cells': '-0.307', 'Endometrial stromal cells': '55.4', 'Ovarian stromal cells': '17.0', 'Undifferentiated cells': '0.0', 'T-cells': '0.2', 'B-cells': '0.0', 'Plasma cells': '0.1', 'Nk-cells': '0.0', 'Granulocytes': '1.6', 'Monocytes': '0.0', 'Macrophages': '0.6', 'Hofbauer cells': '0.2', 'Kupffer cells': '0.4', 'Dendritic cells': '0.0', 'Langerhans cells': '0.011', 'Erythroid cells': '-0.070', 'Adipocytes (Subcutaneous)': '-0.497', 'Adipocytes (Visceral)': '-0.407', 'Breast glandular cells (progenitors)': '0.109', 'Adipocytes (Breast)': '-0.339', 'Colon enterocytes': '-0.112', 'Colon enteroendocrine cells': '0.339', 'Enteric glia cells': '0.513', 'Mitotic cells (Colon)': '-0.033', 'Mitotic cells (Heart)': '0.253', 'Podocytes': '-0.194', 'Ascending Loop of Henle cells': '0.494', 'Intercalated cells': '-0.030', 'Cholangiocyte': '0.152', 'NK-cells (Liver)': '-0.007', 'Respiratory ciliated cells': '0.466', 'Mitotic cells (Lung)': '0.061', 'NK-cells (Lung)': '-0.006', 'B-cells (Lung)': '0.107', 'Alpha cells': '0.225', 'Beta cells': '0.038', 'Prostate glandular cells': '-0.078', 'Prostate basal glandular cells': '0.392', 'Urothelial cells': '0.343', 'Keratinocyte (other)': '-0.385', 'Keratinocyte (granular)': '-0.470', 'Hair cortex cells': '0.545', 'Inner root sheath cells': '0.682', 'Outer root sheath cells': '0.679', 'Sebaceous gland cells': '0.133', 'Eccrine sweat gland cells': '0.383', 'Adipocytes (Skin)': '0.288', 'Mitotic cells (Skin)': '0.305', 'Parietal cells': '-0.641', 'Chief cells': '-0.621', 'Gastric mucous cells': '-0.368', 'Gastric enteroendocrine cells': '-0.403', 'Mitotic cells (Stomach)': '0.026', 'Parafollicular cells': '0.054', 'Thyroid glandular cells': '0.115', 'Mitotic cells (Thyroid)': '0.257', 'Adrenal cortex cells': '0.202', 'Adrenal medulla cells': '-0.097', 'Mitotic cells (Adrenal gland)': '-0.048', 'Minor salivary glandular cells': '-0.075', 'Minor salivary gland ductal cells': '-0.178', 'Minor salivary gland basal cells': '0.444', 'Mitotic cells (Minor salivary gland)': '0.509', 'Adipocytes (Minor salivary gland)': '0.205', 'Somatotropes': '0.145', 'Lactotropes': '0.278', 'Gonadotropes': '0.136', 'Corticotropes': '0.091', 'Thyrotropes': '0.247', 'Undifferentiated cells (Pituitary gland)': '0.010', 'Mitotic cells (Spleen)': '-0.258', 'Platelets': '-0.130', 'Erythrocytes': '-0.112', 'Hematopoietic stem cells': '-0.282', 'B-cells (Spleen)': '0.129', 'NK-cells (Spleen)': '0.314', 'Amygdala excitatory': '48.0', 'Cerebellar inhibitory': '44.0', 'Cge interneuron': '97.1', 'Deep-layer corticothalamic and 6b': '6.2', 'Deep-layer intratelencephalic': '21.1', 'Deep-layer near-projecting': '30.0', 'Eccentric medium spiny neuron': '69.1', 'Hippocampal ca1-3': '11.8', 'Hippocampal ca4': '25.2', 'Hippocampal dentate gyrus': '117.0', 'Lamp5-lhx6 and chandelier': '34.2', 'Lower rhombic lip': '70.4', 'Mammillary body': '2.4', 'Medium spiny neuron': '174.7', 'Mge interneuron': '39.1', 'Midbrain-derived inhibitory': '1.7', 'Miscellaneous': '69.1', 'Splatter': '62.7', 'Thalamic excitatory': '113.5', 'Upper rhombic lip': '141.6', 'Upper-layer intratelencephalic': '30.6', 'Astrocyte': '135.0', 'Bergmann glia': '193.6', 'Central nervous system macrophage': '7.1', 'Choroid plexus epithelial cell': '256.3', 'Committed oligodendrocyte precursor': '33.6', 'Ependymal cell': '493.6', 'Oligodendrocyte': '2.3', 'Oligodendrocyte precursor cell': '65.3', 'Endothelial cell': '32.2', 'Pericyte': '3.6', 'Vascular associated smooth muscle cell': '54.9', 'Fibroblast': '47.7', 'Leukocyte': '1.3', 'Basophil': '13.5', 'Eosinophil': '0.0', 'Neutrophil': '4.1', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '2.3', 'T-reg': '2.5', 'GdT-cell': '0.1', 'MAIT T-cell': '2.5', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '4.1', 'Myeloid DC': '2.4', 'NK-cell': '0.0', 'Total PBMC': '1.3', 'Vd2 gdTCR': '1.6', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '2.5', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '3.4', 'Central memory CD8 T-cell': '2.2', 'Effector memory CD8 T-cell': '2.0', 'Terminal effector memory CD8 T-cell': '2.4', 'Non-switched memory B-cell': '3.1', 'Plasmablast': '2.3', 'Switched memory B-cell': '3.3', 'Exhausted memory B-cell': '4.1', 'Progenitor cell': '2.5', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
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2KES
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{'Adipose Tissue': 5.344149418604651, 'Adrenal Gland': 0.905022480620155, 'Bladder': 1.267552380952381, 'Blood': 0.04724018729817, 'Blood Vessel': 6.352508539325843, 'Brain': 3.577011945495837, 'Breast': 2.9110298474945537, 'Cervix Uteri': 26.247105263157895, 'Colon': 1.8073888318356868, 'Esophagus': 1.0860244775086505, 'Fallopian Tube': 4.528111111111111, 'Heart': 0.6268391869918699, 'Kidney': 1.2312552808988764, 'Liver': 0.2608563274336283, 'Lung': 1.6442996539792387, 'Muscle': 0.263904396014944, 'Nerve': 3.2478862681744753, 'Ovary': 25.75625555555556, 'Pancreas': 0.0820531158536585, 'Pituitary': 2.6382381625441695, 'Prostate': 5.662102448979591, 'Salivary Gland': 0.6982803086419753, 'Skin': 1.514619701492537, 'Small Intestine': 1.890746524064171, 'Spleen': 8.236390041493776, 'Stomach': 1.1189440111420612, 'Testis': 7.81190027700831, 'Thyroid': 1.796037442572741, 'Uterus': 23.114978873239433, 'Vagina': 5.683616025641025}
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27.08, 32.76, 29.34, 32.67, 27.6, 29.1, 29.67, 32.68, 28.93, 30.28, 34.78, 27.81, 27.58, 28.48, 35.4, 34.76, 41.84, 40.31, 59.2, 61.17, 62.38, 69.65, 79.75, 82.51, 83.03, 84.03, 86.34, 86.55, 87.4, 88.38, 89.56, 90.05, 90.67, 91.12, 91.32, 92.4, 92.88, 92.61, 90.1, 88.81, 83.39, 83.37, 81.18, 76.17, 68.97, 60.15, 61.89, 58.78, 61.07, 68.97, 77.38, 84.6, 83.85, 84.94, 88.41, 90.12, 91.7, 91.02, 91.27, 92.15, 93.41, 92.9, 92.98, 94.32, 95.25, 95.04, 95.38, 95.88, 95.47, 95.41, 94.42, 95.74, 94.25, 93.0, 93.07, 93.7, 92.75, 90.6, 90.7, 91.21, 89.07, 87.31, 87.86, 86.06, 88.0, 87.96, 90.01, 90.96, 89.21, 90.32, 91.77, 93.16, 94.24, 91.91, 91.92, 92.98, 93.6, 94.58, 94.97, 93.8, 94.97, 96.18, 96.25, 95.64, 95.99, 95.66, 97.19, 95.65, 95.65, 95.25, 94.98, 94.11, 94.07, 93.23, 90.93, 88.17, 85.4, 81.88, 78.67, 75.25, 77.83, 76.15, 81.2, 78.93, 79.82, 78.98, 79.05, 74.59, 81.78, 87.19, 89.57, 91.57, 93.02, 93.93, 94.59, 94.84, 95.77, 95.39, 95.58, 95.95, 95.33, 96.77, 96.17, 96.35, 96.6, 96.19, 95.81, 95.37, 94.21, 93.66, 92.89, 91.85, 91.29, 90.03, 89.59, 85.28, 84.74, 85.65, 84.93, 85.68, 85.83, 87.83, 92.49, 92.1, 91.32, 91.83, 92.78, 94.73, 94.7, 95.36, 96.4, 96.66, 96.19, 96.88, 97.03, 96.43, 96.2, 96.38, 97.44, 96.87, 96.82, 97.29, 97.19, 96.84, 96.52, 95.95, 94.92, 93.9, 92.95, 90.64, 92.28, 91.27, 93.09, 91.52, 92.01, 95.27, 95.11, 95.27, 94.42, 94.82, 95.67, 95.93, 96.34, 96.95, 96.72, 96.4, 97.12, 96.48, 95.45, 95.71, 95.45, 97.38, 96.18, 96.72, 97.35, 97.2, 97.18, 97.74, 96.91, 96.42, 96.1, 95.61, 94.28, 94.17, 93.32, 90.04, 90.71, 93.68, 91.52, 90.63, 93.99, 95.61, 94.32, 95.11, 96.03, 95.42, 95.42, 95.32, 94.3, 95.02, 94.63, 93.72, 94.83, 95.64, 94.15, 93.94, 95.09, 94.72, 93.99, 93.06, 92.24, 92.46, 91.65, 90.79, 88.47, 86.21, 87.39, 85.31, 79.34, 74.04, 71.06, 57.98, 52.47, 51.37, 44.42, 36.99, 43.54, 42.13, 35.34, 40.98, 39.0, 35.72, 41.83, 41.88, 38.76, 38.19, 46.69, 35.78, 42.35, 37.66, 39.86, 45.03, 38.07, 35.34, 37.44, 39.65, 45.92, 39.35, 50.45, 40.4, 42.47, 40.16, 37.46, 35.51, 36.94, 36.4, 37.53, 41.59, 42.44, 38.02, 38.95, 38.53, 36.54, 40.13, 41.02, 39.63, 39.48, 34.66, 35.19, 33.76, 33.19, 31.7, 34.93, 34.05, 36.72, 34.93, 34.23, 35.89, 39.48, 38.26, 44.16, 47.2, 49.49, 57.25, 66.17, 67.2, 61.71, 75.29, 74.05, 62.94, 69.64, 72.54, 65.95, 58.91, 56.62, 66.74, 51.09, 58.12, 52.63, 53.61, 51.96, 49.54, 48.29, 54.19, 43.82, 43.13, 40.55, 37.55, 39.65, 37.73, 38.44, 34.25, 37.86, 32.55, 33.17, 34.71, 32.58, 33.91, 35.14, 34.81, 29.82, 35.0, 38.87, 34.48, 44.38, 41.54, 46.79, 55.53, 62.87, 56.46, 67.84, 72.86, 65.17, 70.8, 74.15, 73.79, 70.75, 74.57, 76.57, 69.52, 69.96, 66.82, 56.18, 47.03, 49.25, 47.35, 47.16, 42.67, 41.41, 40.64, 34.69, 35.8, 35.79, 37.77, 39.71, 39.55, 36.81, 37.48, 39.57, 35.27, 35.29, 35.16, 37.44, 37.57, 33.23, 38.27, 36.93, 38.24, 37.85, 31.09, 36.49, 32.78, 33.39, 30.75, 34.17, 28.93, 32.76, 32.43, 35.14, 36.25, 35.29, 36.32, 37.37, 33.27, 37.14, 37.99, 30.05, 31.06, 35.99, 38.91, 34.46, 32.12, 29.54, 35.5, 25.3, 27.44, 28.01, 28.11, 30.43, 30.26, 38.42, 34.16, 35.52, 46.39, 39.5, 33.71, 42.6, 37.99, 35.72, 44.07, 36.69, 42.53, 39.57, 37.89, 38.45, 38.83, 30.73, 41.01, 33.0, 47.21, 33.52, 35.82, 33.97, 34.16, 39.14, 37.92, 48.43, 38.34, 40.44, 37.21, 38.28, 38.83, 36.45, 41.84, 37.32, 35.17, 35.9, 31.62, 37.04, 36.36, 44.15, 36.0, 37.94, 39.53, 38.18, 37.2, 32.81, 38.88, 35.09, 33.01, 37.11, 32.18, 45.6, 29.33, 35.04, 32.51, 33.89, 30.33, 32.03, 30.46, 32.4, 30.99, 37.18, 32.7, 41.64, 35.44, 42.81, 37.94, 42.93, 39.49, 42.49, 43.14, 33.48, 45.35, 37.71, 40.36, 39.05, 43.79, 46.67, 46.14, 35.29, 42.07, 40.72, 37.38, 36.89, 36.67, 40.93, 39.67, 42.25, 34.11, 40.15, 29.89, 33.17, 31.14, 27.22, 31.32, 30.37, 31.39, 27.33, 25.8, 32.25, 31.02, 31.82, 34.96, 35.66, 38.68, 40.55, 42.46, 41.47, 41.53, 38.63, 39.28, 37.75, 37.65, 35.77, 31.2, 31.17, 34.39, 28.49, 30.28, 28.81, 29.65, 29.4, 30.63, 29.08, 30.96, 31.42, 32.55, 31.74, 39.63, 28.89, 37.4, 30.93, 34.6, 40.88, 29.05, 40.71, 28.39, 30.54, 30.76, 33.86, 28.99, 28.24, 30.94, 30.84, 33.33, 31.33, 30.79, 35.5, 32.28, 33.87, 32.23, 36.19, 37.31, 34.64, 37.06, 32.03, 34.73, 30.71, 36.83, 33.99, 36.24, 35.46, 35.62, 35.09, 37.25, 38.09, 35.24, 42.08, 34.94, 43.03, 36.97, 42.55, 40.06, 37.89, 36.55, 46.14, 38.8, 39.65, 41.16, 39.46, 46.41, 41.41, 43.8, 43.94, 42.28, 43.0, 45.62, 49.13]
|
[1.0, 0.97, 0.93, 0.88, 0.92, 0.93, 0.85, 0.83, 0.71, 0.93, 0.93, 0.56, 0.76, 0.8, 0.68, 0.85, 0.81, 0.79, 0.73, 0.86, 0.71, 0.93, 0.8, 0.96, 0.99, 0.98, 0.93, 0.92, 0.81, 0.91, 0.89, 0.92, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 0.98, 0.96, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.97, 0.94, 0.98, 0.87, 0.97, 0.95, 0.89, 0.86, 0.9, 0.88, 0.73, 0.92, 0.87, 0.92, 0.88, 0.84, 0.87, 0.93, 0.88, 0.8, 0.93, 0.78, 0.92, 0.86, 0.91, 0.86, 0.96, 0.93, 0.99, 0.97, 0.98, 1.0, 1.0, 1.0, 0.93, 1.0, 0.96, 1.0, 1.0, 0.94, 0.98, 0.87, 0.86, 0.94, 0.93, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.84, 0.96, 0.97, 0.83, 0.84, 0.82, 0.85, 0.69, 0.83, 0.7, 0.85, 0.67, 0.78, 0.57, 0.83, 0.88, 0.55, 0.65, 0.85, 0.75, 0.8, 0.85, 0.87, 0.73, 0.91, 0.62, 0.81, 0.86, 0.85, 0.67, 0.7, 0.89, 0.77, 0.9, 0.93, 0.92, 0.97, 0.99, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.98, 0.9, 0.99, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.89, 0.99, 0.9, 0.97, 0.91, 0.77, 0.63, 0.78, 0.71, 0.87, 0.81, 0.54, 0.84, 0.99, 0.88, 0.97, 0.87, 0.97, 0.87, 1.0, 0.91, 0.97, 0.92, 0.96, 0.97, 0.95, 0.9, 0.96, 0.99, 1.0, 1.0, 0.99, 1.0, 0.82, 0.98, 0.7, 0.42, 0.8, 0.79, 0.47, 0.71, 0.38, 0.66, 0.56, 0.61, 0.61, 0.36, 0.16, 0.67, 0.35, 0.02, 0.13, 0.49, 0.1, 0.0, 0.4, 0.66, 0.25, 0.4, 0.22, 0.7, 0.43, 0.15, 0.74, 0.84, 0.25, 0.69, 0.27, 0.96, 0.47, 0.16, 0.43, 0.66, 0.03, 0.46, 0.22, 0.96, 0.48, 0.31, 0.11, 0.01, 0.0, 0.0, 0.0, 0.03, 0.0, 0.0, 0.17, 0.48, 0.31, 0.26, 0.17, 0.66, 0.0, 0.0, 0.41, 0.49, 0.0, 0.07, 0.74, 0.69, 0.15, 0.34, 0.46, 0.75, 0.06, 0.02, 0.5, 0.33, 0.29, 0.06, 0.7, 0.42, 0.55, 0.01, 0.0, 0.0, 0.01, 0.0, 0.08, 0.0, 0.0, 0.32, 0.47, 0.38, 0.26, 0.31, 0.55, 0.0, 0.0, 0.44, 0.25, 0.01, 0.0, 0.36, 0.56, 0.08, 0.37, 0.02, 0.18, 0.36, 0.09, 0.01, 0.3, 0.26, 0.51, 0.71, 0.81, 0.35, 0.3, 0.0, 0.0, 0.01, 0.02, 0.08, 0.0, 0.0, 0.1, 0.16, 0.3, 0.21, 0.47, 0.79, 0.01, 0.0, 0.43, 0.2, 0.0, 0.02, 0.45, 0.13, 0.0, 0.61, 0.46, 0.18, 0.81, 0.18, 0.51, 0.17, 0.38, 0.23, 0.45, 0.2, 0.46, 0.21, 0.08, 0.05, 0.03, 0.01, 0.02, 0.0, 0.08, 0.0, 0.0, 0.27, 0.3, 0.3, 0.35, 0.23, 0.27, 0.02, 0.0, 0.36, 0.06, 0.02, 0.24, 0.81, 0.26, 0.64, 0.08, 0.32, 0.03, 0.52, 0.21, 0.64, 0.11, 0.69, 0.63, 0.4, 0.23, 0.31, 0.0, 0.06, 0.42, 0.02, 0.0, 0.64, 0.55, 0.58, 0.58, 0.29, 0.64, 0.68, 0.03, 0.11, 0.74, 0.3, 0.0, 0.45, 0.54, 0.12, 0.12, 0.56, 0.52, 0.57, 0.6, 0.5, 0.44, 0.59, 0.46, 0.51, 0.68, 0.58, 0.52, 0.39, 0.67, 0.48, 0.65, 0.51, 0.54, 0.59, 0.46, 0.61, 0.47, 0.5, 0.45, 0.44, 0.6, 0.61, 0.5, 0.49, 0.6, 0.47, 0.63, 0.65, 0.49, 0.51, 0.44, 0.69, 0.62, 0.58, 0.7, 0.75, 0.87, 0.75, 0.93, 0.85, 0.91, 0.87, 0.95, 0.98, 0.98, 0.99, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 1.0, 0.94, 1.0, 0.97, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 1.0, 1.0, 0.9, 1.0, 0.87, 1.0, 0.99, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 0.95, 0.82, 0.71, 0.86, 0.54, 0.6, 0.64, 0.41, 0.42, 0.49, 0.51, 0.39, 0.41, 0.87, 0.75, 0.32, 0.43, 0.74, 0.8, 0.54, 0.17, 0.72, 0.63, 0.46, 0.65, 0.53, 0.49, 0.68, 0.71, 0.63, 0.51, 0.8, 0.73, 0.81, 0.82, 0.81, 0.73, 0.89, 0.75, 0.87, 0.74, 0.9, 0.94, 0.86, 0.95, 0.88, 0.68, 0.64, 0.67, 0.79, 0.41, 0.41, 0.63, 0.69, 0.35, 0.21, 0.44, 0.52, 0.19, 0.62, 0.59, 0.32, 0.49, 0.66, 0.51, 0.53, 0.73, 0.62, 0.66, 0.5, 0.86, 0.86, 0.99, 0.99, 1.0, 0.96, 1.0, 0.95, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.83, 0.99, 0.83, 0.98, 0.98, 0.98, 0.97, 0.99, 0.99, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.96, 0.95, 0.95, 0.8, 0.99, 0.92, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.97, 0.98, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 0.96, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 0.98, 0.98, 0.83, 0.99, 0.89, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.96, 0.95, 0.93, 0.99, 0.98, 1.0, 0.98, 1.0, 0.97, 0.89, 0.95, 0.92, 0.97, 0.99, 0.97, 0.99, 0.98, 0.85, 0.93, 0.72, 0.9, 0.76, 0.75, 0.8, 0.87, 0.9, 0.85, 0.84, 0.77, 0.88, 0.91, 0.95, 0.91, 0.94, 0.97, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 1.0, 0.98, 0.97, 0.81, 0.87, 0.9, 0.95, 0.94, 1.0, 0.99, 0.97, 0.96, 0.99, 0.94, 1.0, 0.88, 0.87, 0.88, 0.89, 0.96, 1.0, 0.98, 1.0, 1.0, 0.97, 0.99, 0.96, 0.98, 0.95, 0.99, 0.92, 1.0, 1.0, 1.0, 0.93, 1.0, 0.91, 0.96, 0.94, 0.95, 0.96, 1.0, 0.97, 0.98, 1.0, 0.97, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0]
|
RING finger
|
component of some large E3 complex possibly composed of UBE2D1, SIAH2, CACYBP/SIP, SKP1, APC and TBL1X
| null | null |
CACYBP, SNCAIP, VAV1, DYRK2, NR1D1, DCC, EGLN2, AXIN1, NR1D2, PEG10, PEG3, UBE2D1, SIAH2, SKP1, APC , TBL1X
|
GPS2, POU2AF1, PML, NCOR1,DCC,BAG1,SYP,DYRK2, TRAF2, SNCA, NR1D1 , NR1D2,EGLN2 , EGLN3,AXIN1
|
mono
| null |
UBE2E2, UBE2D1
|
Homodimer
| null | 83.865802
| 0.456049
| 52.189804
| 0.761839
| 615
|
O43567
|
O43567
|
22199232, hUbiquitome
|
UbiNet, UbiBrowser, 31181401
|
RNF13
|
MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHLILVPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSSQEENEVTEHTPLLRPLASVSAQSFGALSESRSHQNMTESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
|
Homo sapiens
|
Endoplasmic reticulum membrane, Late endosome membrane, Lysosome membrane, Nucleus inner membrane
|
Low tissue specificity
|
{'Ciliated cells': '38.5', 'Basal respiratory cells': '79.1', 'Club cells': '59.9', 'Ionocytes': '53.7', 'Mucus glandular cells': '77.8', 'Serous glandular cells': '84.2', 'Gastric mucus-secreting cells': '34.8', 'Proximal enterocytes': '37.1', 'Paneth cells': '41.2', 'Distal enterocytes': '27.1', 'Intestinal goblet cells': '30.2', 'Exocrine glandular cells': '-0.548', 'Basal prostatic cells': '50.7', 'Prostatic glandular cells': '81.0', 'Breast glandular cells': '0.309', 'Breast myoepithelial cells': '0.411', 'Glandular and luminal cells': '41.3', 'Secretory cells': '44.1', 'Basal keratinocytes': '57.7', 'Suprabasal keratinocytes': '64.4', 'Basal squamous epithelial cells': '62.0', 'Squamous epithelial cells': '50.9', 'Alveolar cells type 1': '0.189', 'Alveolar cells type 2': '0.245', 'Salivary duct cells': '63.7', 'Ductal cells': '0.510', 'Hepatocytes': '0.610', 'Cholangiocytes': '51.5', 'Proximal tubular cells': '0.235', 'Distal tubular cells': '27.7', 'Collecting duct cells': '56.4', 'Mesothelial cells': '0.361', 'Sertoli cells': '0.714', 'Granulosa cells': '33.1', 'Enteroendocrine cells': '24.6', 'Pancreatic endocrine cells': '35.7', 'Leydig cells': '0.679', 'Excitatory neurons': '118.0', 'Inhibitory neurons': '94.7', 'Cone photoreceptor cells': '86.7', 'Rod photoreceptor cells': '31.9', 'Bipolar cells': '38.2', 'Horizontal cells': '25.8', 'Astrocytes': '74.6', 'Oligodendrocyte precursor cells': '108.5', 'Oligodendrocytes': '550.3', 'Microglial cells': '88.6', 'Muller glia cells': '93.7', 'Schwann cells': '0.131', 'Spermatogonia': '0.586', 'Spermatocytes': '0.217', 'Early spermatids': '-0.455', 'Late spermatids': '-0.725', 'Oocytes': '20.6', 'Cytotrophoblasts': '101.9', 'Syncytiotrophoblasts': '52.2', 'Extravillous trophoblasts': '90.0', 'Endothelial cells': '66.7', 'Lymphatic endothelial cells': '46.0', 'Cardiomyocytes': '0.556', 'Skeletal myocytes': '-0.149', 'Smooth muscle cells': '53.8', 'Adipocytes': '96.2', 'Melanocytes': '0.137', 'Fibroblasts': '82.4', 'Peritubular cells': '0.535', 'Endometrial stromal cells': '34.2', 'Ovarian stromal cells': '55.6', 'Undifferentiated cells': '33.3', 'T-cells': '45.3', 'B-cells': '52.3', 'Plasma cells': '58.7', 'Nk-cells': '37.5', 'Granulocytes': '47.7', 'Monocytes': '341.7', 'Macrophages': '173.2', 'Hofbauer cells': '203.2', 'Kupffer cells': '150.0', 'Dendritic cells': '85.7', 'Langerhans cells': '0.299', 'Erythroid cells': '-0.040', 'Adipocytes (Subcutaneous)': '-0.101', 'Adipocytes (Visceral)': '-0.227', 'Breast glandular cells (progenitors)': '0.193', 'Adipocytes (Breast)': '-0.307', 'Colon enterocytes': '-0.211', 'Colon enteroendocrine cells': '0.371', 'Enteric glia cells': '0.248', 'Mitotic cells (Colon)': '-0.083', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.013', 'Ascending Loop of Henle cells': '0.459', 'Intercalated cells': '0.077', 'Cholangiocyte': '0.337', 'NK-cells (Liver)': '-0.332', 'Respiratory ciliated cells': '-0.104', 'Mitotic cells (Lung)': '0.111', 'NK-cells (Lung)': '-0.107', 'B-cells (Lung)': '-0.218', 'Alpha cells': '0.363', 'Beta cells': '0.177', 'Prostate glandular cells': '0.180', 'Prostate basal glandular cells': '0.218', 'Urothelial cells': '-0.046', 'Keratinocyte (other)': '0.201', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '-0.069', 'Inner root sheath cells': '-0.006', 'Outer root sheath cells': '0.184', 'Sebaceous gland cells': '0.130', 'Eccrine sweat gland cells': '0.163', 'Adipocytes (Skin)': '-0.054', 'Mitotic cells (Skin)': '0.284', 'Parietal cells': '-0.537', 'Chief cells': '-0.360', 'Gastric mucous cells': '-0.457', 'Gastric enteroendocrine cells': '-0.316', 'Mitotic cells (Stomach)': '-0.083', 'Parafollicular cells': '0.086', 'Thyroid glandular cells': '0.516', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.638', 'Adrenal medulla cells': '0.039', 'Mitotic cells (Adrenal gland)': '0.379', 'Minor salivary glandular cells': '0.629', 'Minor salivary gland ductal cells': '0.293', 'Minor salivary gland basal cells': '0.110', 'Mitotic cells (Minor salivary gland)': '0.127', 'Adipocytes (Minor salivary gland)': '0.080', 'Somatotropes': '-0.313', 'Lactotropes': '-0.291', 'Gonadotropes': '-0.038', 'Corticotropes': '-0.147', 'Thyrotropes': '0.052', 'Undifferentiated cells (Pituitary gland)': '0.510', 'Mitotic cells (Spleen)': '-0.191', 'Platelets': '0.080', 'Erythrocytes': '-0.172', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '-0.039', 'NK-cells (Spleen)': '0.167', 'Amygdala excitatory': '136.4', 'Cerebellar inhibitory': '138.4', 'Cge interneuron': '119.7', 'Deep-layer corticothalamic and 6b': '191.2', 'Deep-layer intratelencephalic': '179.1', 'Deep-layer near-projecting': '144.8', 'Eccentric medium spiny neuron': '140.8', 'Hippocampal ca1-3': '189.4', 'Hippocampal ca4': '128.9', 'Hippocampal dentate gyrus': '145.3', 'Lamp5-lhx6 and chandelier': '135.4', 'Lower rhombic lip': '206.6', 'Mammillary body': '179.8', 'Medium spiny neuron': '155.5', 'Mge interneuron': '132.9', 'Midbrain-derived inhibitory': '173.9', 'Miscellaneous': '169.2', 'Splatter': '134.7', 'Thalamic excitatory': '163.2', 'Upper rhombic lip': '161.0', 'Upper-layer intratelencephalic': '165.1', 'Astrocyte': '168.4', 'Bergmann glia': '224.8', 'Central nervous system macrophage': '446.0', 'Choroid plexus epithelial cell': '253.4', 'Committed oligodendrocyte precursor': '350.1', 'Ependymal cell': '188.5', 'Oligodendrocyte': '835.0', 'Oligodendrocyte precursor cell': '209.5', 'Endothelial cell': '148.0', 'Pericyte': '121.3', 'Vascular associated smooth muscle cell': '109.9', 'Fibroblast': '178.4', 'Leukocyte': '233.4', 'Basophil': '159.5', 'Eosinophil': '106.7', 'Neutrophil': '1409.5', 'Classical monocyte': '100.4', 'Non-classical monocyte': '199.2', 'Intermediate monocyte': '445.1', 'T-reg': '111.3', 'GdT-cell': '37.5', 'MAIT T-cell': '129.3', 'Memory CD4 T-cell': '41.7', 'Naive CD4 T-cell': '45.1', 'Memory CD8 T-cell': '44.8', 'Naive CD8 T-cell': '38.9', 'Memory B-cell': '52.1', 'Naive B-cell': '77.6', 'Plasmacytoid DC': '269.7', 'Myeloid DC': '219.1', 'NK-cell': '44.2', 'Total PBMC': '231.7', 'Vd2 gdTCR': '109.8', 'Memory CD4 T-cell Th1\\/Th17': '56.2', 'Memory CD4 T-cell Th17': '45.6', 'Memory CD4 T-cell Th2': '44.3', 'Non-Vd2 gdTCR': '133.7', 'Memory CD4 T-cell Th1': '39.4', 'Memory CD4 T-cell TFH': '34.7', 'Terminal effector memory CD4 T-cell': '106.7', 'Central memory CD8 T-cell': '108.5', 'Effector memory CD8 T-cell': '116.1', 'Terminal effector memory CD8 T-cell': '132.4', 'Non-switched memory B-cell': '116.2', 'Plasmablast': '143.8', 'Switched memory B-cell': '120.4', 'Exhausted memory B-cell': '100.3', 'Progenitor cell': '87.3', 'Memory T-reg': '34.8', 'Naive CD4 T-cell activated': '24.3', 'Naive CD8 T-cell activated': '23.8', 'Naive T-reg': '52.5'}
|
5ZBU, 5ZC4
|
{'Adipose Tissue': 47.9686488372093, 'Adrenal Gland': 28.21803488372093, 'Bladder': 39.88809523809524, 'Blood': 48.95557588805167, 'Blood Vessel': 47.11647191011236, 'Brain': 39.46729939439818, 'Breast': 45.09564270152506, 'Cervix Uteri': 40.65157894736842, 'Colon': 34.55081386392811, 'Esophagus': 32.24009965397924, 'Fallopian Tube': 40.75888888888889, 'Heart': 13.39619512195122, 'Kidney': 21.98579775280899, 'Liver': 19.190132743362835, 'Lung': 58.762318339100354, 'Muscle': 18.24131631382316, 'Nerve': 91.83071082390951, 'Ovary': 34.75988888888889, 'Pancreas': 14.960314024390245, 'Pituitary': 23.31625441696113, 'Prostate': 35.94285714285714, 'Salivary Gland': 41.412901234567904, 'Skin': 35.99586511885019, 'Small Intestine': 29.067272727272726, 'Spleen': 40.915767634854774, 'Stomach': 26.77373259052925, 'Testis': 24.197770083102498, 'Thyroid': 47.93137825421133, 'Uterus': 44.375492957746474, 'Vagina': 38.95467948717949}
|
RNF13
|
MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHLILVPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSSQEENEVTEHTPLLRPLASVSAQSFGALSESRSHQNMTESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
|
Homo sapiens
|
Endoplasmic reticulum membrane, Late endosome membrane, Lysosome membrane, Nucleus inner membrane
|
Low tissue specificity
|
{'Ciliated cells': '38.5', 'Basal respiratory cells': '79.1', 'Club cells': '59.9', 'Ionocytes': '53.7', 'Mucus glandular cells': '77.8', 'Serous glandular cells': '84.2', 'Gastric mucus-secreting cells': '34.8', 'Proximal enterocytes': '37.1', 'Paneth cells': '41.2', 'Distal enterocytes': '27.1', 'Intestinal goblet cells': '30.2', 'Exocrine glandular cells': '-0.548', 'Basal prostatic cells': '50.7', 'Prostatic glandular cells': '81.0', 'Breast glandular cells': '0.309', 'Breast myoepithelial cells': '0.411', 'Glandular and luminal cells': '41.3', 'Secretory cells': '44.1', 'Basal keratinocytes': '57.7', 'Suprabasal keratinocytes': '64.4', 'Basal squamous epithelial cells': '62.0', 'Squamous epithelial cells': '50.9', 'Alveolar cells type 1': '0.189', 'Alveolar cells type 2': '0.245', 'Salivary duct cells': '63.7', 'Ductal cells': '0.510', 'Hepatocytes': '0.610', 'Cholangiocytes': '51.5', 'Proximal tubular cells': '0.235', 'Distal tubular cells': '27.7', 'Collecting duct cells': '56.4', 'Mesothelial cells': '0.361', 'Sertoli cells': '0.714', 'Granulosa cells': '33.1', 'Enteroendocrine cells': '24.6', 'Pancreatic endocrine cells': '35.7', 'Leydig cells': '0.679', 'Excitatory neurons': '118.0', 'Inhibitory neurons': '94.7', 'Cone photoreceptor cells': '86.7', 'Rod photoreceptor cells': '31.9', 'Bipolar cells': '38.2', 'Horizontal cells': '25.8', 'Astrocytes': '74.6', 'Oligodendrocyte precursor cells': '108.5', 'Oligodendrocytes': '550.3', 'Microglial cells': '88.6', 'Muller glia cells': '93.7', 'Schwann cells': '0.131', 'Spermatogonia': '0.586', 'Spermatocytes': '0.217', 'Early spermatids': '-0.455', 'Late spermatids': '-0.725', 'Oocytes': '20.6', 'Cytotrophoblasts': '101.9', 'Syncytiotrophoblasts': '52.2', 'Extravillous trophoblasts': '90.0', 'Endothelial cells': '66.7', 'Lymphatic endothelial cells': '46.0', 'Cardiomyocytes': '0.556', 'Skeletal myocytes': '-0.149', 'Smooth muscle cells': '53.8', 'Adipocytes': '96.2', 'Melanocytes': '0.137', 'Fibroblasts': '82.4', 'Peritubular cells': '0.535', 'Endometrial stromal cells': '34.2', 'Ovarian stromal cells': '55.6', 'Undifferentiated cells': '33.3', 'T-cells': '45.3', 'B-cells': '52.3', 'Plasma cells': '58.7', 'Nk-cells': '37.5', 'Granulocytes': '47.7', 'Monocytes': '341.7', 'Macrophages': '173.2', 'Hofbauer cells': '203.2', 'Kupffer cells': '150.0', 'Dendritic cells': '85.7', 'Langerhans cells': '0.299', 'Erythroid cells': '-0.040', 'Adipocytes (Subcutaneous)': '-0.101', 'Adipocytes (Visceral)': '-0.227', 'Breast glandular cells (progenitors)': '0.193', 'Adipocytes (Breast)': '-0.307', 'Colon enterocytes': '-0.211', 'Colon enteroendocrine cells': '0.371', 'Enteric glia cells': '0.248', 'Mitotic cells (Colon)': '-0.083', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.013', 'Ascending Loop of Henle cells': '0.459', 'Intercalated cells': '0.077', 'Cholangiocyte': '0.337', 'NK-cells (Liver)': '-0.332', 'Respiratory ciliated cells': '-0.104', 'Mitotic cells (Lung)': '0.111', 'NK-cells (Lung)': '-0.107', 'B-cells (Lung)': '-0.218', 'Alpha cells': '0.363', 'Beta cells': '0.177', 'Prostate glandular cells': '0.180', 'Prostate basal glandular cells': '0.218', 'Urothelial cells': '-0.046', 'Keratinocyte (other)': '0.201', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '-0.069', 'Inner root sheath cells': '-0.006', 'Outer root sheath cells': '0.184', 'Sebaceous gland cells': '0.130', 'Eccrine sweat gland cells': '0.163', 'Adipocytes (Skin)': '-0.054', 'Mitotic cells (Skin)': '0.284', 'Parietal cells': '-0.537', 'Chief cells': '-0.360', 'Gastric mucous cells': '-0.457', 'Gastric enteroendocrine cells': '-0.316', 'Mitotic cells (Stomach)': '-0.083', 'Parafollicular cells': '0.086', 'Thyroid glandular cells': '0.516', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.638', 'Adrenal medulla cells': '0.039', 'Mitotic cells (Adrenal gland)': '0.379', 'Minor salivary glandular cells': '0.629', 'Minor salivary gland ductal cells': '0.293', 'Minor salivary gland basal cells': '0.110', 'Mitotic cells (Minor salivary gland)': '0.127', 'Adipocytes (Minor salivary gland)': '0.080', 'Somatotropes': '-0.313', 'Lactotropes': '-0.291', 'Gonadotropes': '-0.038', 'Corticotropes': '-0.147', 'Thyrotropes': '0.052', 'Undifferentiated cells (Pituitary gland)': '0.510', 'Mitotic cells (Spleen)': '-0.191', 'Platelets': '0.080', 'Erythrocytes': '-0.172', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '-0.039', 'NK-cells (Spleen)': '0.167', 'Amygdala excitatory': '136.4', 'Cerebellar inhibitory': '138.4', 'Cge interneuron': '119.7', 'Deep-layer corticothalamic and 6b': '191.2', 'Deep-layer intratelencephalic': '179.1', 'Deep-layer near-projecting': '144.8', 'Eccentric medium spiny neuron': '140.8', 'Hippocampal ca1-3': '189.4', 'Hippocampal ca4': '128.9', 'Hippocampal dentate gyrus': '145.3', 'Lamp5-lhx6 and chandelier': '135.4', 'Lower rhombic lip': '206.6', 'Mammillary body': '179.8', 'Medium spiny neuron': '155.5', 'Mge interneuron': '132.9', 'Midbrain-derived inhibitory': '173.9', 'Miscellaneous': '169.2', 'Splatter': '134.7', 'Thalamic excitatory': '163.2', 'Upper rhombic lip': '161.0', 'Upper-layer intratelencephalic': '165.1', 'Astrocyte': '168.4', 'Bergmann glia': '224.8', 'Central nervous system macrophage': '446.0', 'Choroid plexus epithelial cell': '253.4', 'Committed oligodendrocyte precursor': '350.1', 'Ependymal cell': '188.5', 'Oligodendrocyte': '835.0', 'Oligodendrocyte precursor cell': '209.5', 'Endothelial cell': '148.0', 'Pericyte': '121.3', 'Vascular associated smooth muscle cell': '109.9', 'Fibroblast': '178.4', 'Leukocyte': '233.4', 'Basophil': '159.5', 'Eosinophil': '106.7', 'Neutrophil': '1409.5', 'Classical monocyte': '100.4', 'Non-classical monocyte': '199.2', 'Intermediate monocyte': '445.1', 'T-reg': '111.3', 'GdT-cell': '37.5', 'MAIT T-cell': '129.3', 'Memory CD4 T-cell': '41.7', 'Naive CD4 T-cell': '45.1', 'Memory CD8 T-cell': '44.8', 'Naive CD8 T-cell': '38.9', 'Memory B-cell': '52.1', 'Naive B-cell': '77.6', 'Plasmacytoid DC': '269.7', 'Myeloid DC': '219.1', 'NK-cell': '44.2', 'Total PBMC': '231.7', 'Vd2 gdTCR': '109.8', 'Memory CD4 T-cell Th1\\/Th17': '56.2', 'Memory CD4 T-cell Th17': '45.6', 'Memory CD4 T-cell Th2': '44.3', 'Non-Vd2 gdTCR': '133.7', 'Memory CD4 T-cell Th1': '39.4', 'Memory CD4 T-cell TFH': '34.7', 'Terminal effector memory CD4 T-cell': '106.7', 'Central memory CD8 T-cell': '108.5', 'Effector memory CD8 T-cell': '116.1', 'Terminal effector memory CD8 T-cell': '132.4', 'Non-switched memory B-cell': '116.2', 'Plasmablast': '143.8', 'Switched memory B-cell': '120.4', 'Exhausted memory B-cell': '100.3', 'Progenitor cell': '87.3', 'Memory T-reg': '34.8', 'Naive CD4 T-cell activated': '24.3', 'Naive CD8 T-cell activated': '23.8', 'Naive T-reg': '52.5'}
|
5ZBU, 5ZC4
|
{'Adipose Tissue': 47.9686488372093, 'Adrenal Gland': 28.21803488372093, 'Bladder': 39.88809523809524, 'Blood': 48.95557588805167, 'Blood Vessel': 47.11647191011236, 'Brain': 39.46729939439818, 'Breast': 45.09564270152506, 'Cervix Uteri': 40.65157894736842, 'Colon': 34.55081386392811, 'Esophagus': 32.24009965397924, 'Fallopian Tube': 40.75888888888889, 'Heart': 13.39619512195122, 'Kidney': 21.98579775280899, 'Liver': 19.190132743362835, 'Lung': 58.762318339100354, 'Muscle': 18.24131631382316, 'Nerve': 91.83071082390951, 'Ovary': 34.75988888888889, 'Pancreas': 14.960314024390245, 'Pituitary': 23.31625441696113, 'Prostate': 35.94285714285714, 'Salivary Gland': 41.412901234567904, 'Skin': 35.99586511885019, 'Small Intestine': 29.067272727272726, 'Spleen': 40.915767634854774, 'Stomach': 26.77373259052925, 'Testis': 24.197770083102498, 'Thyroid': 47.93137825421133, 'Uterus': 44.375492957746474, 'Vagina': 38.95467948717949}
|
[38.76, 39.11, 36.6, 49.76, 45.32, 44.15, 48.63, 49.43, 54.53, 57.09, 63.94, 62.75, 68.18, 68.82, 70.28, 71.3, 74.78, 74.58, 74.1, 74.98, 76.32, 72.98, 71.02, 65.48, 63.57, 61.11, 59.81, 56.29, 57.67, 45.81, 46.64, 39.97, 48.05, 52.36, 79.97, 91.61, 92.97, 94.93, 94.89, 92.18, 89.55, 89.46, 84.18, 90.68, 90.66, 92.09, 91.81, 92.82, 91.2, 92.05, 91.39, 90.73, 91.05, 87.69, 87.29, 80.79, 82.55, 83.17, 84.96, 84.76, 79.0, 82.13, 88.05, 91.47, 93.01, 94.34, 95.43, 97.25, 96.5, 97.55, 98.07, 97.55, 97.6, 97.38, 97.47, 98.13, 97.63, 97.06, 97.88, 98.23, 97.41, 95.48, 93.42, 89.51, 79.02, 66.45, 64.08, 61.63, 60.04, 65.12, 81.54, 92.26, 96.21, 97.26, 98.36, 98.62, 98.73, 98.43, 95.31, 93.65, 95.37, 95.09, 95.19, 96.57, 95.36, 96.09, 97.37, 97.41, 96.59, 98.09, 98.27, 97.01, 97.26, 97.25, 95.53, 96.77, 94.88, 95.98, 97.56, 98.05, 98.22, 98.22, 97.36, 96.31, 95.09, 96.75, 95.46, 96.06, 92.96, 92.1, 91.79, 91.77, 89.31, 87.21, 85.03, 90.57, 89.26, 90.67, 89.75, 87.86, 90.31, 93.16, 94.94, 93.35, 95.02, 94.12, 94.71, 94.63, 95.59, 96.94, 97.4, 97.8, 97.57, 96.65, 97.93, 97.65, 96.32, 96.74, 95.37, 93.99, 92.99, 95.75, 94.52, 91.64, 90.7, 91.36, 89.45, 92.97, 94.06, 95.75, 93.46, 93.11, 88.12, 82.81, 68.62, 58.85, 55.68, 55.42, 56.93, 63.99, 68.18, 70.74, 72.8, 79.73, 79.89, 80.1, 83.46, 85.0, 87.39, 87.86, 88.22, 87.42, 89.72, 88.8, 93.01, 92.36, 91.05, 91.85, 91.09, 91.98, 93.31, 91.5, 91.96, 90.25, 89.74, 90.4, 89.12, 86.87, 84.32, 84.45, 78.82, 78.69, 75.55, 75.71, 72.96, 70.44, 80.12, 76.36, 78.86, 79.51, 80.38, 77.84, 84.12, 80.65, 83.54, 85.23, 87.65, 89.06, 89.78, 91.31, 90.77, 89.57, 83.97, 83.19, 84.66, 82.96, 81.05, 84.11, 92.52, 95.03, 92.47, 92.69, 94.96, 92.19, 93.84, 92.6, 91.47, 91.06, 90.29, 89.18, 91.56, 92.73, 92.95, 92.63, 91.56, 91.51, 88.04, 91.49, 89.56, 93.4, 93.35, 95.61, 95.52, 92.37, 92.41, 93.45, 93.4, 92.27, 89.9, 89.86, 89.21, 86.06, 84.41, 85.65, 86.22, 86.79, 90.34, 91.83, 92.48, 91.03, 91.74, 89.81, 88.55, 86.72, 84.19, 75.56, 62.39, 56.75, 49.53, 48.48, 45.32, 38.54, 44.76, 40.49, 43.43, 37.46, 36.61, 34.62, 39.29, 35.65, 37.88, 34.75, 32.37, 33.06, 33.56, 32.32, 33.21, 28.84, 30.96, 33.55, 28.28, 32.66, 30.2, 33.17, 31.39, 24.27, 26.92, 28.75, 26.67, 24.18, 30.45, 24.1, 24.79, 28.5, 23.65, 31.35, 25.38, 23.13, 30.23, 21.13, 30.39, 24.6, 30.67, 24.97, 30.0, 26.09, 29.97, 26.2, 28.34, 26.06, 30.83, 30.73, 30.73, 30.12, 31.62, 32.92, 33.12, 31.32, 29.91, 27.32, 28.96, 26.9, 29.06, 26.62, 30.37, 26.19, 24.8, 28.82, 24.82, 29.6, 31.89, 29.67, 33.53, 32.55, 32.76, 30.56, 33.84, 35.89, 39.68, 36.85, 36.36, 36.13, 37.79, 37.53, 39.73, 39.52, 39.59, 41.25, 35.99, 40.2, 42.5]
|
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|
[38.76, 39.11, 36.6, 49.76, 45.32, 44.15, 48.63, 49.43, 54.53, 57.09, 63.94, 62.75, 68.18, 68.82, 70.28, 71.3, 74.78, 74.58, 74.1, 74.98, 76.32, 72.98, 71.02, 65.48, 63.57, 61.11, 59.81, 56.29, 57.67, 45.81, 46.64, 39.97, 48.05, 52.36, 79.97, 91.61, 92.97, 94.93, 94.89, 92.18, 89.55, 89.46, 84.18, 90.68, 90.66, 92.09, 91.81, 92.82, 91.2, 92.05, 91.39, 90.73, 91.05, 87.69, 87.29, 80.79, 82.55, 83.17, 84.96, 84.76, 79.0, 82.13, 88.05, 91.47, 93.01, 94.34, 95.43, 97.25, 96.5, 97.55, 98.07, 97.55, 97.6, 97.38, 97.47, 98.13, 97.63, 97.06, 97.88, 98.23, 97.41, 95.48, 93.42, 89.51, 79.02, 66.45, 64.08, 61.63, 60.04, 65.12, 81.54, 92.26, 96.21, 97.26, 98.36, 98.62, 98.73, 98.43, 95.31, 93.65, 95.37, 95.09, 95.19, 96.57, 95.36, 96.09, 97.37, 97.41, 96.59, 98.09, 98.27, 97.01, 97.26, 97.25, 95.53, 96.77, 94.88, 95.98, 97.56, 98.05, 98.22, 98.22, 97.36, 96.31, 95.09, 96.75, 95.46, 96.06, 92.96, 92.1, 91.79, 91.77, 89.31, 87.21, 85.03, 90.57, 89.26, 90.67, 89.75, 87.86, 90.31, 93.16, 94.94, 93.35, 95.02, 94.12, 94.71, 94.63, 95.59, 96.94, 97.4, 97.8, 97.57, 96.65, 97.93, 97.65, 96.32, 96.74, 95.37, 93.99, 92.99, 95.75, 94.52, 91.64, 90.7, 91.36, 89.45, 92.97, 94.06, 95.75, 93.46, 93.11, 88.12, 82.81, 68.62, 58.85, 55.68, 55.42, 56.93, 63.99, 68.18, 70.74, 72.8, 79.73, 79.89, 80.1, 83.46, 85.0, 87.39, 87.86, 88.22, 87.42, 89.72, 88.8, 93.01, 92.36, 91.05, 91.85, 91.09, 91.98, 93.31, 91.5, 91.96, 90.25, 89.74, 90.4, 89.12, 86.87, 84.32, 84.45, 78.82, 78.69, 75.55, 75.71, 72.96, 70.44, 80.12, 76.36, 78.86, 79.51, 80.38, 77.84, 84.12, 80.65, 83.54, 85.23, 87.65, 89.06, 89.78, 91.31, 90.77, 89.57, 83.97, 83.19, 84.66, 82.96, 81.05, 84.11, 92.52, 95.03, 92.47, 92.69, 94.96, 92.19, 93.84, 92.6, 91.47, 91.06, 90.29, 89.18, 91.56, 92.73, 92.95, 92.63, 91.56, 91.51, 88.04, 91.49, 89.56, 93.4, 93.35, 95.61, 95.52, 92.37, 92.41, 93.45, 93.4, 92.27, 89.9, 89.86, 89.21, 86.06, 84.41, 85.65, 86.22, 86.79, 90.34, 91.83, 92.48, 91.03, 91.74, 89.81, 88.55, 86.72, 84.19, 75.56, 62.39, 56.75, 49.53, 48.48, 45.32, 38.54, 44.76, 40.49, 43.43, 37.46, 36.61, 34.62, 39.29, 35.65, 37.88, 34.75, 32.37, 33.06, 33.56, 32.32, 33.21, 28.84, 30.96, 33.55, 28.28, 32.66, 30.2, 33.17, 31.39, 24.27, 26.92, 28.75, 26.67, 24.18, 30.45, 24.1, 24.79, 28.5, 23.65, 31.35, 25.38, 23.13, 30.23, 21.13, 30.39, 24.6, 30.67, 24.97, 30.0, 26.09, 29.97, 26.2, 28.34, 26.06, 30.83, 30.73, 30.73, 30.12, 31.62, 32.92, 33.12, 31.32, 29.91, 27.32, 28.96, 26.9, 29.06, 26.62, 30.37, 26.19, 24.8, 28.82, 24.82, 29.6, 31.89, 29.67, 33.53, 32.55, 32.76, 30.56, 33.84, 35.89, 39.68, 36.85, 36.36, 36.13, 37.79, 37.53, 39.73, 39.52, 39.59, 41.25, 35.99, 40.2, 42.5]
|
[0.91, 0.86, 0.83, 0.68, 0.76, 0.65, 0.79, 0.58, 0.79, 0.58, 0.44, 0.7, 0.63, 0.51, 0.48, 0.67, 0.44, 0.41, 0.52, 0.37, 0.66, 0.28, 0.56, 0.67, 0.49, 0.29, 0.65, 0.58, 0.38, 0.72, 0.54, 0.43, 0.76, 0.1, 0.3, 0.0, 0.28, 0.0, 0.27, 0.19, 0.76, 0.88, 0.68, 0.45, 0.68, 0.4, 0.65, 0.03, 0.63, 0.11, 0.29, 0.43, 0.2, 0.8, 0.07, 0.47, 0.66, 0.97, 0.18, 0.3, 0.68, 0.87, 0.17, 0.18, 0.56, 0.05, 0.27, 0.01, 0.2, 0.41, 0.03, 0.69, 0.42, 0.56, 0.24, 0.0, 0.41, 0.75, 0.83, 0.09, 0.6, 0.76, 0.19, 0.43, 0.87, 0.37, 0.92, 0.99, 0.52, 0.91, 0.28, 0.24, 0.05, 0.0, 0.0, 0.03, 0.0, 0.41, 0.32, 0.57, 0.76, 0.39, 0.64, 0.16, 0.02, 0.38, 0.0, 0.0, 0.11, 0.07, 0.0, 0.24, 0.69, 0.17, 0.54, 0.03, 0.58, 0.0, 0.0, 0.0, 0.0, 0.06, 0.01, 0.17, 0.86, 0.27, 0.5, 0.66, 0.37, 0.28, 0.53, 0.0, 0.38, 0.28, 0.93, 0.44, 0.63, 0.71, 0.2, 0.25, 0.77, 0.53, 0.05, 0.65, 0.07, 0.06, 0.06, 0.01, 0.0, 0.0, 0.06, 0.26, 0.48, 0.2, 0.0, 0.42, 0.28, 0.0, 0.24, 0.67, 0.61, 0.02, 0.12, 0.31, 0.96, 0.45, 0.35, 0.0, 0.16, 0.0, 0.23, 0.0, 0.18, 0.11, 0.5, 0.42, 0.5, 0.25, 0.45, 0.7, 0.71, 0.48, 0.43, 0.51, 0.45, 0.24, 0.63, 0.66, 0.38, 0.47, 0.41, 0.3, 0.36, 0.5, 0.59, 0.59, 0.58, 0.54, 0.55, 0.25, 0.66, 0.6, 0.54, 0.41, 0.44, 0.69, 0.59, 0.67, 0.47, 0.54, 0.64, 0.76, 0.55, 0.51, 0.63, 0.54, 0.48, 0.11, 0.81, 0.71, 0.57, 0.24, 0.06, 0.68, 0.48, 0.05, 0.57, 0.54, 0.42, 0.72, 0.05, 0.76, 0.75, 0.98, 0.33, 0.98, 0.34, 0.63, 0.55, 0.0, 0.46, 0.38, 0.35, 0.73, 0.57, 0.77, 0.07, 0.71, 0.5, 0.54, 0.24, 0.6, 0.01, 0.08, 0.26, 0.03, 0.55, 0.15, 0.52, 0.29, 0.1, 0.01, 0.13, 0.14, 0.89, 0.23, 0.0, 0.22, 0.42, 0.4, 0.0, 0.2, 0.71, 0.54, 0.57, 0.29, 0.25, 0.02, 0.29, 0.52, 0.45, 0.74, 0.55, 0.62, 0.04, 0.71, 0.23, 0.8, 0.96, 0.87, 0.55, 0.95, 0.75, 0.82, 0.85, 0.71, 0.86, 0.8, 0.84, 0.87, 0.73, 0.79, 0.82, 0.79, 0.76, 0.68, 0.89, 0.93, 0.92, 0.95, 0.96, 0.9, 0.96, 0.89, 0.95, 0.97, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 1.0, 1.0, 0.99, 0.98, 0.9, 0.96, 0.9, 0.88, 0.92, 0.81, 0.91, 0.83, 0.55, 0.85, 0.83, 0.91, 0.82, 0.74, 0.74, 0.67, 0.83, 0.77, 0.83, 0.85, 0.86, 0.78, 0.95, 0.94, 0.95, 0.93, 0.98, 0.9, 0.98, 0.94, 0.93, 0.92, 0.82, 0.82, 0.71, 0.87, 0.84, 0.93, 0.95, 0.96, 0.89, 0.97, 0.84, 0.89, 0.81, 0.91, 0.89, 0.85, 0.91, 0.9, 1.0]
|
RING finger
| null | null | null |
ERN1
| null | null | null | null | null | null | 72.478845
| 0.525512
| 72.478845
| 0.525512
| 2,043
|
O43567
|
O95295
|
22890573
|
UbiNet, UbiBrowser, 31181401
|
RNF13
|
MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHLILVPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSSQEENEVTEHTPLLRPLASVSAQSFGALSESRSHQNMTESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
|
Homo sapiens
|
Endoplasmic reticulum membrane, Late endosome membrane, Lysosome membrane, Nucleus inner membrane
|
Low tissue specificity
|
{'Ciliated cells': '38.5', 'Basal respiratory cells': '79.1', 'Club cells': '59.9', 'Ionocytes': '53.7', 'Mucus glandular cells': '77.8', 'Serous glandular cells': '84.2', 'Gastric mucus-secreting cells': '34.8', 'Proximal enterocytes': '37.1', 'Paneth cells': '41.2', 'Distal enterocytes': '27.1', 'Intestinal goblet cells': '30.2', 'Exocrine glandular cells': '-0.548', 'Basal prostatic cells': '50.7', 'Prostatic glandular cells': '81.0', 'Breast glandular cells': '0.309', 'Breast myoepithelial cells': '0.411', 'Glandular and luminal cells': '41.3', 'Secretory cells': '44.1', 'Basal keratinocytes': '57.7', 'Suprabasal keratinocytes': '64.4', 'Basal squamous epithelial cells': '62.0', 'Squamous epithelial cells': '50.9', 'Alveolar cells type 1': '0.189', 'Alveolar cells type 2': '0.245', 'Salivary duct cells': '63.7', 'Ductal cells': '0.510', 'Hepatocytes': '0.610', 'Cholangiocytes': '51.5', 'Proximal tubular cells': '0.235', 'Distal tubular cells': '27.7', 'Collecting duct cells': '56.4', 'Mesothelial cells': '0.361', 'Sertoli cells': '0.714', 'Granulosa cells': '33.1', 'Enteroendocrine cells': '24.6', 'Pancreatic endocrine cells': '35.7', 'Leydig cells': '0.679', 'Excitatory neurons': '118.0', 'Inhibitory neurons': '94.7', 'Cone photoreceptor cells': '86.7', 'Rod photoreceptor cells': '31.9', 'Bipolar cells': '38.2', 'Horizontal cells': '25.8', 'Astrocytes': '74.6', 'Oligodendrocyte precursor cells': '108.5', 'Oligodendrocytes': '550.3', 'Microglial cells': '88.6', 'Muller glia cells': '93.7', 'Schwann cells': '0.131', 'Spermatogonia': '0.586', 'Spermatocytes': '0.217', 'Early spermatids': '-0.455', 'Late spermatids': '-0.725', 'Oocytes': '20.6', 'Cytotrophoblasts': '101.9', 'Syncytiotrophoblasts': '52.2', 'Extravillous trophoblasts': '90.0', 'Endothelial cells': '66.7', 'Lymphatic endothelial cells': '46.0', 'Cardiomyocytes': '0.556', 'Skeletal myocytes': '-0.149', 'Smooth muscle cells': '53.8', 'Adipocytes': '96.2', 'Melanocytes': '0.137', 'Fibroblasts': '82.4', 'Peritubular cells': '0.535', 'Endometrial stromal cells': '34.2', 'Ovarian stromal cells': '55.6', 'Undifferentiated cells': '33.3', 'T-cells': '45.3', 'B-cells': '52.3', 'Plasma cells': '58.7', 'Nk-cells': '37.5', 'Granulocytes': '47.7', 'Monocytes': '341.7', 'Macrophages': '173.2', 'Hofbauer cells': '203.2', 'Kupffer cells': '150.0', 'Dendritic cells': '85.7', 'Langerhans cells': '0.299', 'Erythroid cells': '-0.040', 'Adipocytes (Subcutaneous)': '-0.101', 'Adipocytes (Visceral)': '-0.227', 'Breast glandular cells (progenitors)': '0.193', 'Adipocytes (Breast)': '-0.307', 'Colon enterocytes': '-0.211', 'Colon enteroendocrine cells': '0.371', 'Enteric glia cells': '0.248', 'Mitotic cells (Colon)': '-0.083', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.013', 'Ascending Loop of Henle cells': '0.459', 'Intercalated cells': '0.077', 'Cholangiocyte': '0.337', 'NK-cells (Liver)': '-0.332', 'Respiratory ciliated cells': '-0.104', 'Mitotic cells (Lung)': '0.111', 'NK-cells (Lung)': '-0.107', 'B-cells (Lung)': '-0.218', 'Alpha cells': '0.363', 'Beta cells': '0.177', 'Prostate glandular cells': '0.180', 'Prostate basal glandular cells': '0.218', 'Urothelial cells': '-0.046', 'Keratinocyte (other)': '0.201', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '-0.069', 'Inner root sheath cells': '-0.006', 'Outer root sheath cells': '0.184', 'Sebaceous gland cells': '0.130', 'Eccrine sweat gland cells': '0.163', 'Adipocytes (Skin)': '-0.054', 'Mitotic cells (Skin)': '0.284', 'Parietal cells': '-0.537', 'Chief cells': '-0.360', 'Gastric mucous cells': '-0.457', 'Gastric enteroendocrine cells': '-0.316', 'Mitotic cells (Stomach)': '-0.083', 'Parafollicular cells': '0.086', 'Thyroid glandular cells': '0.516', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.638', 'Adrenal medulla cells': '0.039', 'Mitotic cells (Adrenal gland)': '0.379', 'Minor salivary glandular cells': '0.629', 'Minor salivary gland ductal cells': '0.293', 'Minor salivary gland basal cells': '0.110', 'Mitotic cells (Minor salivary gland)': '0.127', 'Adipocytes (Minor salivary gland)': '0.080', 'Somatotropes': '-0.313', 'Lactotropes': '-0.291', 'Gonadotropes': '-0.038', 'Corticotropes': '-0.147', 'Thyrotropes': '0.052', 'Undifferentiated cells (Pituitary gland)': '0.510', 'Mitotic cells (Spleen)': '-0.191', 'Platelets': '0.080', 'Erythrocytes': '-0.172', 'Hematopoietic stem cells': '0.051', 'B-cells (Spleen)': '-0.039', 'NK-cells (Spleen)': '0.167', 'Amygdala excitatory': '136.4', 'Cerebellar inhibitory': '138.4', 'Cge interneuron': '119.7', 'Deep-layer corticothalamic and 6b': '191.2', 'Deep-layer intratelencephalic': '179.1', 'Deep-layer near-projecting': '144.8', 'Eccentric medium spiny neuron': '140.8', 'Hippocampal ca1-3': '189.4', 'Hippocampal ca4': '128.9', 'Hippocampal dentate gyrus': '145.3', 'Lamp5-lhx6 and chandelier': '135.4', 'Lower rhombic lip': '206.6', 'Mammillary body': '179.8', 'Medium spiny neuron': '155.5', 'Mge interneuron': '132.9', 'Midbrain-derived inhibitory': '173.9', 'Miscellaneous': '169.2', 'Splatter': '134.7', 'Thalamic excitatory': '163.2', 'Upper rhombic lip': '161.0', 'Upper-layer intratelencephalic': '165.1', 'Astrocyte': '168.4', 'Bergmann glia': '224.8', 'Central nervous system macrophage': '446.0', 'Choroid plexus epithelial cell': '253.4', 'Committed oligodendrocyte precursor': '350.1', 'Ependymal cell': '188.5', 'Oligodendrocyte': '835.0', 'Oligodendrocyte precursor cell': '209.5', 'Endothelial cell': '148.0', 'Pericyte': '121.3', 'Vascular associated smooth muscle cell': '109.9', 'Fibroblast': '178.4', 'Leukocyte': '233.4', 'Basophil': '159.5', 'Eosinophil': '106.7', 'Neutrophil': '1409.5', 'Classical monocyte': '100.4', 'Non-classical monocyte': '199.2', 'Intermediate monocyte': '445.1', 'T-reg': '111.3', 'GdT-cell': '37.5', 'MAIT T-cell': '129.3', 'Memory CD4 T-cell': '41.7', 'Naive CD4 T-cell': '45.1', 'Memory CD8 T-cell': '44.8', 'Naive CD8 T-cell': '38.9', 'Memory B-cell': '52.1', 'Naive B-cell': '77.6', 'Plasmacytoid DC': '269.7', 'Myeloid DC': '219.1', 'NK-cell': '44.2', 'Total PBMC': '231.7', 'Vd2 gdTCR': '109.8', 'Memory CD4 T-cell Th1\\/Th17': '56.2', 'Memory CD4 T-cell Th17': '45.6', 'Memory CD4 T-cell Th2': '44.3', 'Non-Vd2 gdTCR': '133.7', 'Memory CD4 T-cell Th1': '39.4', 'Memory CD4 T-cell TFH': '34.7', 'Terminal effector memory CD4 T-cell': '106.7', 'Central memory CD8 T-cell': '108.5', 'Effector memory CD8 T-cell': '116.1', 'Terminal effector memory CD8 T-cell': '132.4', 'Non-switched memory B-cell': '116.2', 'Plasmablast': '143.8', 'Switched memory B-cell': '120.4', 'Exhausted memory B-cell': '100.3', 'Progenitor cell': '87.3', 'Memory T-reg': '34.8', 'Naive CD4 T-cell activated': '24.3', 'Naive CD8 T-cell activated': '23.8', 'Naive T-reg': '52.5'}
|
5ZBU, 5ZC4
|
{'Adipose Tissue': 47.9686488372093, 'Adrenal Gland': 28.21803488372093, 'Bladder': 39.88809523809524, 'Blood': 48.95557588805167, 'Blood Vessel': 47.11647191011236, 'Brain': 39.46729939439818, 'Breast': 45.09564270152506, 'Cervix Uteri': 40.65157894736842, 'Colon': 34.55081386392811, 'Esophagus': 32.24009965397924, 'Fallopian Tube': 40.75888888888889, 'Heart': 13.39619512195122, 'Kidney': 21.98579775280899, 'Liver': 19.190132743362835, 'Lung': 58.762318339100354, 'Muscle': 18.24131631382316, 'Nerve': 91.83071082390951, 'Ovary': 34.75988888888889, 'Pancreas': 14.960314024390245, 'Pituitary': 23.31625441696113, 'Prostate': 35.94285714285714, 'Salivary Gland': 41.412901234567904, 'Skin': 35.99586511885019, 'Small Intestine': 29.067272727272726, 'Spleen': 40.915767634854774, 'Stomach': 26.77373259052925, 'Testis': 24.197770083102498, 'Thyroid': 47.93137825421133, 'Uterus': 44.375492957746474, 'Vagina': 38.95467948717949}
|
SNAPIN
|
MAGAGSAAVSGAGTPVAGPTGRDLFAEGLLEFLRPAVQQLDSHVHAVRESQVELREQIDNLATELCRINEDQKVALDLDPYVKKLLNARRRVVLVNNILQNAQERLRRLNHSVAKETARRRAMLDSGIYPPGSPGK
|
Homo sapiens
|
Membrane, Cytoplasm, cytosol, Cytoplasm, perinuclear region, Golgi apparatus membrane, Lysosome membrane, Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
|
Low tissue specificity
|
{'Ciliated cells': '31.6', 'Basal respiratory cells': '82.4', 'Club cells': '32.7', 'Ionocytes': '42.0', 'Mucus glandular cells': '14.4', 'Serous glandular cells': '18.9', 'Gastric mucus-secreting cells': '15.3', 'Proximal enterocytes': '25.3', 'Paneth cells': '30.3', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '22.7', 'Exocrine glandular cells': '-0.706', 'Basal prostatic cells': '21.4', 'Prostatic glandular cells': '17.6', 'Breast glandular cells': '-0.119', 'Breast myoepithelial cells': '-0.136', 'Glandular and luminal cells': '27.0', 'Secretory cells': '36.8', 'Basal keratinocytes': '25.6', 'Suprabasal keratinocytes': '36.4', 'Basal squamous epithelial cells': '35.7', 'Squamous epithelial cells': '45.6', 'Alveolar cells type 1': '-0.025', 'Alveolar cells type 2': '-0.070', 'Salivary duct cells': '17.5', 'Ductal cells': '0.651', 'Hepatocytes': '0.451', 'Cholangiocytes': '40.1', 'Proximal tubular cells': '0.163', 'Distal tubular cells': '64.5', 'Collecting duct cells': '29.2', 'Mesothelial cells': '0.189', 'Sertoli cells': '0.701', 'Granulosa cells': '41.5', 'Enteroendocrine cells': '19.0', 'Pancreatic endocrine cells': '34.0', 'Leydig cells': '0.651', 'Excitatory neurons': '5.7', 'Inhibitory neurons': '6.2', 'Cone photoreceptor cells': '32.3', 'Rod photoreceptor cells': '18.0', 'Bipolar cells': '16.9', 'Horizontal cells': '14.5', 'Astrocytes': '6.8', 'Oligodendrocyte precursor cells': '7.5', 'Oligodendrocytes': '13.4', 'Microglial cells': '4.5', 'Muller glia cells': '83.9', 'Schwann cells': '0.083', 'Spermatogonia': '0.525', 'Spermatocytes': '0.121', 'Early spermatids': '-0.523', 'Late spermatids': '-0.648', 'Oocytes': '114.0', 'Cytotrophoblasts': '66.2', 'Syncytiotrophoblasts': '74.9', 'Extravillous trophoblasts': '51.7', 'Endothelial cells': '34.6', 'Lymphatic endothelial cells': '18.3', 'Cardiomyocytes': '0.757', 'Skeletal myocytes': '0.132', 'Smooth muscle cells': '36.3', 'Adipocytes': '40.2', 'Melanocytes': '0.199', 'Fibroblasts': '31.0', 'Peritubular cells': '0.494', 'Endometrial stromal cells': '24.2', 'Ovarian stromal cells': '46.6', 'Undifferentiated cells': '28.7', 'T-cells': '24.3', 'B-cells': '26.1', 'Plasma cells': '24.5', 'Nk-cells': '36.7', 'Granulocytes': '34.2', 'Monocytes': '17.8', 'Macrophages': '32.2', 'Hofbauer cells': '81.6', 'Kupffer cells': '34.4', 'Dendritic cells': '34.9', 'Langerhans cells': '0.331', 'Erythroid cells': '-0.003', 'Adipocytes (Subcutaneous)': '0.339', 'Adipocytes (Visceral)': '0.297', 'Breast glandular cells (progenitors)': '-0.147', 'Adipocytes (Breast)': '0.368', 'Colon enterocytes': '-0.287', 'Colon enteroendocrine cells': '0.214', 'Enteric glia cells': '0.151', 'Mitotic cells (Colon)': '-0.201', 'Mitotic cells (Heart)': '0.468', 'Podocytes': '-0.038', 'Ascending Loop of Henle cells': '0.478', 'Intercalated cells': '-0.005', 'Cholangiocyte': '0.339', 'NK-cells (Liver)': '-0.265', 'Respiratory ciliated cells': '0.016', 'Mitotic cells (Lung)': '0.165', 'NK-cells (Lung)': '-0.023', 'B-cells (Lung)': '-0.163', 'Alpha cells': '0.415', 'Beta cells': '0.273', 'Prostate glandular cells': '-0.201', 'Prostate basal glandular cells': '0.064', 'Urothelial cells': '0.048', 'Keratinocyte (other)': '0.275', 'Keratinocyte (granular)': '-0.073', 'Hair cortex cells': '0.036', 'Inner root sheath cells': '0.110', 'Outer root sheath cells': '0.234', 'Sebaceous gland cells': '0.068', 'Eccrine sweat gland cells': '-0.091', 'Adipocytes (Skin)': '-0.119', 'Mitotic cells (Skin)': '0.422', 'Parietal cells': '-0.680', 'Chief cells': '-0.624', 'Gastric mucous cells': '-0.442', 'Gastric enteroendocrine cells': '-0.462', 'Mitotic cells (Stomach)': '0.027', 'Parafollicular cells': '0.048', 'Thyroid glandular cells': '0.388', 'Mitotic cells (Thyroid)': '-0.055', 'Adrenal cortex cells': '0.606', 'Adrenal medulla cells': '0.050', 'Mitotic cells (Adrenal gland)': '0.467', 'Minor salivary glandular cells': '0.312', 'Minor salivary gland ductal cells': '-0.212', 'Minor salivary gland basal cells': '0.492', 'Mitotic cells (Minor salivary gland)': '0.612', 'Adipocytes (Minor salivary gland)': '0.306', 'Somatotropes': '-0.245', 'Lactotropes': '-0.322', 'Gonadotropes': '-0.174', 'Corticotropes': '-0.180', 'Thyrotropes': '-0.016', 'Undifferentiated cells (Pituitary gland)': '0.542', 'Mitotic cells (Spleen)': '-0.368', 'Platelets': '-0.087', 'Erythrocytes': '-0.160', 'Hematopoietic stem cells': '-0.218', 'B-cells (Spleen)': '0.235', 'NK-cells (Spleen)': '0.249', 'Amygdala excitatory': '6.6', 'Cerebellar inhibitory': '12.8', 'Cge interneuron': '8.6', 'Deep-layer corticothalamic and 6b': '8.4', 'Deep-layer intratelencephalic': '7.2', 'Deep-layer near-projecting': '7.8', 'Eccentric medium spiny neuron': '6.9', 'Hippocampal ca1-3': '7.2', 'Hippocampal ca4': '10.4', 'Hippocampal dentate gyrus': '8.1', 'Lamp5-lhx6 and chandelier': '10.3', 'Lower rhombic lip': '15.1', 'Mammillary body': '10.6', 'Medium spiny neuron': '6.8', 'Mge interneuron': '8.9', 'Midbrain-derived inhibitory': '8.3', 'Miscellaneous': '8.6', 'Splatter': '10.9', 'Thalamic excitatory': '10.3', 'Upper rhombic lip': '9.9', 'Upper-layer intratelencephalic': '7.2', 'Astrocyte': '17.9', 'Bergmann glia': '28.6', 'Central nervous system macrophage': '14.8', 'Choroid plexus epithelial cell': '9.9', 'Committed oligodendrocyte precursor': '18.1', 'Ependymal cell': '16.6', 'Oligodendrocyte': '23.9', 'Oligodendrocyte precursor cell': '15.7', 'Endothelial cell': '13.8', 'Pericyte': '22.9', 'Vascular associated smooth muscle cell': '20.6', 'Fibroblast': '11.4', 'Leukocyte': '9.2', 'Basophil': '31.0', 'Eosinophil': '140.1', 'Neutrophil': '27.4', 'Classical monocyte': '45.0', 'Non-classical monocyte': '43.6', 'Intermediate monocyte': '75.8', 'T-reg': '40.8', 'GdT-cell': '87.1', 'MAIT T-cell': '38.6', 'Memory CD4 T-cell': '88.5', 'Naive CD4 T-cell': '25.8', 'Memory CD8 T-cell': '89.0', 'Naive CD8 T-cell': '22.7', 'Memory B-cell': '130.6', 'Naive B-cell': '18.6', 'Plasmacytoid DC': '94.3', 'Myeloid DC': '73.0', 'NK-cell': '38.8', 'Total PBMC': '74.6', 'Vd2 gdTCR': '42.5', 'Memory CD4 T-cell TFH': '25.6', 'Memory CD4 T-cell Th2': '24.5', 'Memory CD4 T-cell Th17': '28.3', 'Memory CD4 T-cell Th1\\/Th17': '24.8', 'Non-Vd2 gdTCR': '37.4', 'Memory CD4 T-cell Th1': '24.2', 'Terminal effector memory CD4 T-cell': '36.5', 'Central memory CD8 T-cell': '35.3', 'Effector memory CD8 T-cell': '33.0', 'Terminal effector memory CD8 T-cell': '51.3', 'Switched memory B-cell': '59.6', 'Plasmablast': '57.6', 'Non-switched memory B-cell': '64.4', 'Exhausted memory B-cell': '56.7', 'Progenitor cell': '45.8', 'Naive CD4 T-cell activated': '45.0', 'Naive CD8 T-cell activated': '52.0', 'Memory T-reg': '33.8', 'Naive T-reg': '25.2'}
| null |
{'Adipose Tissue': 46.17412790697674, 'Adrenal Gland': 52.79639534883721, 'Bladder': 48.90761904761904, 'Blood': 23.039131324004305, 'Blood Vessel': 55.981505617977525, 'Brain': 30.63945382286147, 'Breast': 44.48106753812637, 'Cervix Uteri': 52.84368421052631, 'Colon': 42.98713093709884, 'Esophagus': 47.011792387543245, 'Fallopian Tube': 51.32666666666667, 'Heart': 31.13824854819977, 'Kidney': 30.548426966292133, 'Liver': 18.102858407079648, 'Lung': 37.21851211072664, 'Muscle': 43.90429638854297, 'Nerve': 47.54008077544427, 'Ovary': 48.26455555555556, 'Pancreas': 10.829490853658536, 'Pituitary': 32.99434628975265, 'Prostate': 45.67857142857143, 'Salivary Gland': 28.416975308641977, 'Skin': 39.74040353786622, 'Small Intestine': 32.36957219251337, 'Spleen': 44.40414937759336, 'Stomach': 30.139632311977717, 'Testis': 38.29337950138504, 'Thyroid': 54.88713629402757, 'Uterus': 55.511760563380285, 'Vagina': 41.94820512820513}
|
[38.76, 39.11, 36.6, 49.76, 45.32, 44.15, 48.63, 49.43, 54.53, 57.09, 63.94, 62.75, 68.18, 68.82, 70.28, 71.3, 74.78, 74.58, 74.1, 74.98, 76.32, 72.98, 71.02, 65.48, 63.57, 61.11, 59.81, 56.29, 57.67, 45.81, 46.64, 39.97, 48.05, 52.36, 79.97, 91.61, 92.97, 94.93, 94.89, 92.18, 89.55, 89.46, 84.18, 90.68, 90.66, 92.09, 91.81, 92.82, 91.2, 92.05, 91.39, 90.73, 91.05, 87.69, 87.29, 80.79, 82.55, 83.17, 84.96, 84.76, 79.0, 82.13, 88.05, 91.47, 93.01, 94.34, 95.43, 97.25, 96.5, 97.55, 98.07, 97.55, 97.6, 97.38, 97.47, 98.13, 97.63, 97.06, 97.88, 98.23, 97.41, 95.48, 93.42, 89.51, 79.02, 66.45, 64.08, 61.63, 60.04, 65.12, 81.54, 92.26, 96.21, 97.26, 98.36, 98.62, 98.73, 98.43, 95.31, 93.65, 95.37, 95.09, 95.19, 96.57, 95.36, 96.09, 97.37, 97.41, 96.59, 98.09, 98.27, 97.01, 97.26, 97.25, 95.53, 96.77, 94.88, 95.98, 97.56, 98.05, 98.22, 98.22, 97.36, 96.31, 95.09, 96.75, 95.46, 96.06, 92.96, 92.1, 91.79, 91.77, 89.31, 87.21, 85.03, 90.57, 89.26, 90.67, 89.75, 87.86, 90.31, 93.16, 94.94, 93.35, 95.02, 94.12, 94.71, 94.63, 95.59, 96.94, 97.4, 97.8, 97.57, 96.65, 97.93, 97.65, 96.32, 96.74, 95.37, 93.99, 92.99, 95.75, 94.52, 91.64, 90.7, 91.36, 89.45, 92.97, 94.06, 95.75, 93.46, 93.11, 88.12, 82.81, 68.62, 58.85, 55.68, 55.42, 56.93, 63.99, 68.18, 70.74, 72.8, 79.73, 79.89, 80.1, 83.46, 85.0, 87.39, 87.86, 88.22, 87.42, 89.72, 88.8, 93.01, 92.36, 91.05, 91.85, 91.09, 91.98, 93.31, 91.5, 91.96, 90.25, 89.74, 90.4, 89.12, 86.87, 84.32, 84.45, 78.82, 78.69, 75.55, 75.71, 72.96, 70.44, 80.12, 76.36, 78.86, 79.51, 80.38, 77.84, 84.12, 80.65, 83.54, 85.23, 87.65, 89.06, 89.78, 91.31, 90.77, 89.57, 83.97, 83.19, 84.66, 82.96, 81.05, 84.11, 92.52, 95.03, 92.47, 92.69, 94.96, 92.19, 93.84, 92.6, 91.47, 91.06, 90.29, 89.18, 91.56, 92.73, 92.95, 92.63, 91.56, 91.51, 88.04, 91.49, 89.56, 93.4, 93.35, 95.61, 95.52, 92.37, 92.41, 93.45, 93.4, 92.27, 89.9, 89.86, 89.21, 86.06, 84.41, 85.65, 86.22, 86.79, 90.34, 91.83, 92.48, 91.03, 91.74, 89.81, 88.55, 86.72, 84.19, 75.56, 62.39, 56.75, 49.53, 48.48, 45.32, 38.54, 44.76, 40.49, 43.43, 37.46, 36.61, 34.62, 39.29, 35.65, 37.88, 34.75, 32.37, 33.06, 33.56, 32.32, 33.21, 28.84, 30.96, 33.55, 28.28, 32.66, 30.2, 33.17, 31.39, 24.27, 26.92, 28.75, 26.67, 24.18, 30.45, 24.1, 24.79, 28.5, 23.65, 31.35, 25.38, 23.13, 30.23, 21.13, 30.39, 24.6, 30.67, 24.97, 30.0, 26.09, 29.97, 26.2, 28.34, 26.06, 30.83, 30.73, 30.73, 30.12, 31.62, 32.92, 33.12, 31.32, 29.91, 27.32, 28.96, 26.9, 29.06, 26.62, 30.37, 26.19, 24.8, 28.82, 24.82, 29.6, 31.89, 29.67, 33.53, 32.55, 32.76, 30.56, 33.84, 35.89, 39.68, 36.85, 36.36, 36.13, 37.79, 37.53, 39.73, 39.52, 39.59, 41.25, 35.99, 40.2, 42.5]
|
[0.91, 0.86, 0.83, 0.68, 0.76, 0.65, 0.79, 0.58, 0.79, 0.58, 0.44, 0.7, 0.63, 0.51, 0.48, 0.67, 0.44, 0.41, 0.52, 0.37, 0.66, 0.28, 0.56, 0.67, 0.49, 0.29, 0.65, 0.58, 0.38, 0.72, 0.54, 0.43, 0.76, 0.1, 0.3, 0.0, 0.28, 0.0, 0.27, 0.19, 0.76, 0.88, 0.68, 0.45, 0.68, 0.4, 0.65, 0.03, 0.63, 0.11, 0.29, 0.43, 0.2, 0.8, 0.07, 0.47, 0.66, 0.97, 0.18, 0.3, 0.68, 0.87, 0.17, 0.18, 0.56, 0.05, 0.27, 0.01, 0.2, 0.41, 0.03, 0.69, 0.42, 0.56, 0.24, 0.0, 0.41, 0.75, 0.83, 0.09, 0.6, 0.76, 0.19, 0.43, 0.87, 0.37, 0.92, 0.99, 0.52, 0.91, 0.28, 0.24, 0.05, 0.0, 0.0, 0.03, 0.0, 0.41, 0.32, 0.57, 0.76, 0.39, 0.64, 0.16, 0.02, 0.38, 0.0, 0.0, 0.11, 0.07, 0.0, 0.24, 0.69, 0.17, 0.54, 0.03, 0.58, 0.0, 0.0, 0.0, 0.0, 0.06, 0.01, 0.17, 0.86, 0.27, 0.5, 0.66, 0.37, 0.28, 0.53, 0.0, 0.38, 0.28, 0.93, 0.44, 0.63, 0.71, 0.2, 0.25, 0.77, 0.53, 0.05, 0.65, 0.07, 0.06, 0.06, 0.01, 0.0, 0.0, 0.06, 0.26, 0.48, 0.2, 0.0, 0.42, 0.28, 0.0, 0.24, 0.67, 0.61, 0.02, 0.12, 0.31, 0.96, 0.45, 0.35, 0.0, 0.16, 0.0, 0.23, 0.0, 0.18, 0.11, 0.5, 0.42, 0.5, 0.25, 0.45, 0.7, 0.71, 0.48, 0.43, 0.51, 0.45, 0.24, 0.63, 0.66, 0.38, 0.47, 0.41, 0.3, 0.36, 0.5, 0.59, 0.59, 0.58, 0.54, 0.55, 0.25, 0.66, 0.6, 0.54, 0.41, 0.44, 0.69, 0.59, 0.67, 0.47, 0.54, 0.64, 0.76, 0.55, 0.51, 0.63, 0.54, 0.48, 0.11, 0.81, 0.71, 0.57, 0.24, 0.06, 0.68, 0.48, 0.05, 0.57, 0.54, 0.42, 0.72, 0.05, 0.76, 0.75, 0.98, 0.33, 0.98, 0.34, 0.63, 0.55, 0.0, 0.46, 0.38, 0.35, 0.73, 0.57, 0.77, 0.07, 0.71, 0.5, 0.54, 0.24, 0.6, 0.01, 0.08, 0.26, 0.03, 0.55, 0.15, 0.52, 0.29, 0.1, 0.01, 0.13, 0.14, 0.89, 0.23, 0.0, 0.22, 0.42, 0.4, 0.0, 0.2, 0.71, 0.54, 0.57, 0.29, 0.25, 0.02, 0.29, 0.52, 0.45, 0.74, 0.55, 0.62, 0.04, 0.71, 0.23, 0.8, 0.96, 0.87, 0.55, 0.95, 0.75, 0.82, 0.85, 0.71, 0.86, 0.8, 0.84, 0.87, 0.73, 0.79, 0.82, 0.79, 0.76, 0.68, 0.89, 0.93, 0.92, 0.95, 0.96, 0.9, 0.96, 0.89, 0.95, 0.97, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 1.0, 1.0, 0.99, 0.98, 0.9, 0.96, 0.9, 0.88, 0.92, 0.81, 0.91, 0.83, 0.55, 0.85, 0.83, 0.91, 0.82, 0.74, 0.74, 0.67, 0.83, 0.77, 0.83, 0.85, 0.86, 0.78, 0.95, 0.94, 0.95, 0.93, 0.98, 0.9, 0.98, 0.94, 0.93, 0.92, 0.82, 0.82, 0.71, 0.87, 0.84, 0.93, 0.95, 0.96, 0.89, 0.97, 0.84, 0.89, 0.81, 0.91, 0.89, 0.85, 0.91, 0.9, 1.0]
|
[47.28, 50.01, 45.54, 54.6, 50.85, 52.66, 52.77, 52.66, 58.84, 54.45, 47.14, 54.29, 46.3, 56.92, 54.18, 55.94, 62.97, 68.46, 71.38, 78.03, 83.78, 87.92, 89.97, 89.83, 93.4, 93.57, 93.31, 94.54, 95.52, 94.88, 95.35, 96.28, 96.88, 96.67, 97.22, 97.1, 97.39, 97.71, 97.8, 97.81, 98.25, 98.17, 98.33, 98.46, 98.33, 98.24, 98.56, 98.34, 98.31, 98.12, 98.34, 98.33, 98.1, 98.25, 98.21, 98.22, 98.12, 98.2, 98.26, 97.96, 98.06, 97.27, 97.02, 96.66, 95.11, 91.94, 91.24, 89.86, 86.0, 84.95, 82.95, 77.68, 65.71, 59.84, 61.82, 69.58, 76.85, 85.07, 87.92, 92.34, 94.23, 95.1, 96.75, 96.76, 97.35, 97.87, 98.23, 98.08, 98.07, 98.26, 98.15, 98.25, 98.22, 98.28, 98.51, 98.29, 97.86, 98.31, 98.48, 98.24, 98.4, 98.52, 98.19, 98.34, 98.26, 98.51, 98.16, 97.94, 98.11, 98.04, 97.94, 97.66, 97.31, 97.27, 97.09, 95.49, 96.56, 94.82, 93.7, 92.81, 91.85, 90.07, 85.54, 85.12, 79.45, 74.0, 58.13, 56.0, 52.07, 62.33, 58.04, 50.38, 54.44, 56.44, 54.8, 40.05]
|
[1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.98, 0.86, 0.96, 0.84, 0.88, 0.9, 0.85, 0.96, 0.85, 0.9, 0.86, 0.62, 0.71, 0.5, 0.63, 0.83, 0.45, 0.55, 0.7, 0.42, 0.58, 0.41, 0.46, 0.63, 0.53, 0.77, 0.48, 0.55, 0.54, 0.53, 0.62, 0.59, 0.6, 0.64, 0.53, 0.58, 0.54, 0.55, 0.56, 0.49, 0.53, 0.69, 0.69, 0.56, 0.6, 0.33, 0.56, 0.54, 0.57, 0.58, 0.51, 0.58, 0.55, 0.59, 0.53, 0.43, 0.64, 0.59, 0.55, 0.55, 0.68, 0.47, 0.47, 0.62, 0.61, 0.68, 0.7, 0.65, 0.72, 0.71, 0.56, 0.58, 0.57, 0.44, 0.66, 0.46, 0.66, 0.67, 0.7, 0.4, 0.46, 0.45, 0.68, 0.68, 0.67, 0.65, 0.61, 0.61, 0.63, 0.49, 0.64, 0.58, 0.55, 0.55, 0.56, 0.48, 0.47, 0.41, 0.69, 0.56, 0.59, 0.65, 0.59, 0.58, 0.69, 0.56, 0.54, 0.53, 0.77, 0.38, 0.42, 0.53, 0.61, 0.59, 0.64, 0.49, 0.62, 0.8, 0.8, 0.51, 0.55, 0.79, 0.9, 0.88, 0.93, 0.82, 0.97, 0.93, 0.94, 0.99]
|
RING finger
| null | null | null |
ERN1
| null | null | null | null | null | null | 72.478845
| 0.525512
| 85.29625
| 0.644118
| 2,925
|
O43663
|
P04908
|
22199232, E3Net
|
UbiNet, UbiBrowser, 31181401
|
PRC1
|
MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSFERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAPFCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGNLLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKERAKQERQLKNKKQTETEMLYGSAPRTPSKRRGLAPNTPGKARKLNTTTMSNATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPRTGRHGANKENLELNGSILSGGYPGSAPLQRNFSINSVASTYSEFAKDPSLSDSSTVGLQRELSKASKSDATSGILNSTNIQS
|
Homo sapiens
|
Nucleus, Cytoplasm, Cytoplasm, cytoskeleton, spindle pole, Midbody, Chromosome
|
Tissue enhanced (bone marrow, testis)
|
{'Ciliated cells': '1.9', 'Basal respiratory cells': '4.0', 'Club cells': '2.6', 'Ionocytes': '4.4', 'Mucus glandular cells': '2.0', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '0.6', 'Paneth cells': '4.4', 'Distal enterocytes': '1.4', 'Intestinal goblet cells': '8.6', 'Exocrine glandular cells': '-0.424', 'Basal prostatic cells': '0.4', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.512', 'Breast myoepithelial cells': '0.489', 'Glandular and luminal cells': '5.6', 'Secretory cells': '2.3', 'Basal keratinocytes': '13.6', 'Suprabasal keratinocytes': '9.0', 'Basal squamous epithelial cells': '8.2', 'Squamous epithelial cells': '24.9', 'Alveolar cells type 1': '-0.119', 'Alveolar cells type 2': '-0.065', 'Salivary duct cells': '2.2', 'Ductal cells': '0.452', 'Hepatocytes': '0.350', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.169', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.038', 'Sertoli cells': '-0.086', 'Granulosa cells': '6.8', 'Enteroendocrine cells': '4.0', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '-0.137', 'Excitatory neurons': '4.8', 'Inhibitory neurons': '5.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.5', 'Bipolar cells': '1.4', 'Horizontal cells': '0.6', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '1.6', 'Microglial cells': '1.8', 'Muller glia cells': '1.0', 'Schwann cells': '0.155', 'Spermatogonia': '0.356', 'Spermatocytes': '0.840', 'Early spermatids': '0.496', 'Late spermatids': '0.109', 'Oocytes': '73.5', 'Cytotrophoblasts': '23.6', 'Syncytiotrophoblasts': '9.7', 'Extravillous trophoblasts': '35.1', 'Endothelial cells': '2.1', 'Lymphatic endothelial cells': '3.2', 'Cardiomyocytes': '0.491', 'Skeletal myocytes': '0.090', 'Smooth muscle cells': '5.3', 'Adipocytes': '2.0', 'Melanocytes': '0.520', 'Fibroblasts': '4.4', 'Peritubular cells': '-0.165', 'Endometrial stromal cells': '2.7', 'Ovarian stromal cells': '2.7', 'Undifferentiated cells': '30.0', 'T-cells': '4.1', 'B-cells': '3.2', 'Plasma cells': '15.9', 'Nk-cells': '3.5', 'Granulocytes': '0.2', 'Monocytes': '3.9', 'Macrophages': '4.6', 'Hofbauer cells': '9.7', 'Kupffer cells': '3.6', 'Dendritic cells': '1.6', 'Langerhans cells': '0.161', 'Erythroid cells': '0.185', 'Adipocytes (Subcutaneous)': '-0.201', 'Adipocytes (Visceral)': '-0.143', 'Breast glandular cells (progenitors)': '0.409', 'Adipocytes (Breast)': '-0.476', 'Colon enterocytes': '0.263', 'Colon enteroendocrine cells': '0.079', 'Enteric glia cells': '-0.225', 'Mitotic cells (Colon)': '0.541', 'Mitotic cells (Heart)': '0.604', 'Podocytes': '-0.159', 'Ascending Loop of Henle cells': '0.380', 'Intercalated cells': '-0.085', 'Cholangiocyte': '0.398', 'NK-cells (Liver)': '-0.195', 'Respiratory ciliated cells': '0.056', 'Mitotic cells (Lung)': '0.656', 'NK-cells (Lung)': '0.131', 'B-cells (Lung)': '0.145', 'Alpha cells': '0.302', 'Beta cells': '0.192', 'Prostate glandular cells': '-0.169', 'Prostate basal glandular cells': '0.149', 'Urothelial cells': '0.144', 'Keratinocyte (other)': '0.346', 'Keratinocyte (granular)': '-0.148', 'Hair cortex cells': '0.062', 'Inner root sheath cells': '0.191', 'Outer root sheath cells': '0.198', 'Sebaceous gland cells': '-0.036', 'Eccrine sweat gland cells': '-0.063', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.827', 'Parietal cells': '0.011', 'Chief cells': '-0.010', 'Gastric mucous cells': '0.442', 'Gastric enteroendocrine cells': '0.080', 'Mitotic cells (Stomach)': '0.781', 'Parafollicular cells': '0.050', 'Thyroid glandular cells': '0.042', 'Mitotic cells (Thyroid)': '0.436', 'Adrenal cortex cells': '0.466', 'Adrenal medulla cells': '0.134', 'Mitotic cells (Adrenal gland)': '0.879', 'Minor salivary glandular cells': '0.283', 'Minor salivary gland ductal cells': '-0.271', 'Minor salivary gland basal cells': '0.742', 'Mitotic cells (Minor salivary gland)': '0.849', 'Adipocytes (Minor salivary gland)': '0.243', 'Somatotropes': '-0.356', 'Lactotropes': '-0.338', 'Gonadotropes': '-0.061', 'Corticotropes': '-0.240', 'Thyrotropes': '-0.112', 'Undifferentiated cells (Pituitary gland)': '0.421', 'Mitotic cells (Spleen)': '0.927', 'Platelets': '0.103', 'Erythrocytes': '0.359', 'Hematopoietic stem cells': '0.419', 'B-cells (Spleen)': '-0.133', 'NK-cells (Spleen)': '-0.200', 'Amygdala excitatory': '2.4', 'Cerebellar inhibitory': '3.3', 'Cge interneuron': '3.1', 'Deep-layer corticothalamic and 6b': '3.4', 'Deep-layer intratelencephalic': '2.7', 'Deep-layer near-projecting': '2.7', 'Eccentric medium spiny neuron': '2.1', 'Hippocampal ca1-3': '3.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '2.8', 'Lamp5-lhx6 and chandelier': '2.9', 'Lower rhombic lip': '4.3', 'Mammillary body': '2.9', 'Medium spiny neuron': '2.1', 'Mge interneuron': '3.2', 'Midbrain-derived inhibitory': '3.4', 'Miscellaneous': '3.2', 'Splatter': '4.2', 'Thalamic excitatory': '3.6', 'Upper rhombic lip': '6.7', 'Upper-layer intratelencephalic': '2.4', 'Astrocyte': '1.9', 'Bergmann glia': '0.9', 'Central nervous system macrophage': '1.0', 'Choroid plexus epithelial cell': '1.9', 'Committed oligodendrocyte precursor': '1.2', 'Ependymal cell': '1.4', 'Oligodendrocyte': '1.6', 'Oligodendrocyte precursor cell': '1.4', 'Endothelial cell': '0.5', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '2.9', 'Fibroblast': '1.0', 'Leukocyte': '2.1', 'Basophil': '19.3', 'Eosinophil': '2.9', 'Neutrophil': '0.4', 'Classical monocyte': '9.4', 'Non-classical monocyte': '2.0', 'Intermediate monocyte': '1.7', 'T-reg': '9.6', 'GdT-cell': '0.6', 'MAIT T-cell': '5.1', 'Memory CD4 T-cell': '1.3', 'Naive CD4 T-cell': '3.9', 'Memory CD8 T-cell': '1.3', 'Naive CD8 T-cell': '3.0', 'Memory B-cell': '1.1', 'Naive B-cell': '7.6', 'Plasmacytoid DC': '7.2', 'Myeloid DC': '20.8', 'NK-cell': '5.5', 'Total PBMC': '5.6', 'Vd2 gdTCR': '5.9', 'Memory CD4 T-cell Th1\\/Th17': '5.8', 'Memory CD4 T-cell Th17': '8.8', 'Memory CD4 T-cell Th2': '10.5', 'Non-Vd2 gdTCR': '6.8', 'Memory CD4 T-cell Th1': '7.1', 'Memory CD4 T-cell TFH': '7.0', 'Terminal effector memory CD4 T-cell': '3.2', 'Central memory CD8 T-cell': '6.7', 'Effector memory CD8 T-cell': '11.4', 'Terminal effector memory CD8 T-cell': '4.9', 'Non-switched memory B-cell': '5.4', 'Plasmablast': '30.3', 'Switched memory B-cell': '9.2', 'Exhausted memory B-cell': '12.2', 'Progenitor cell': '8.9', 'Memory T-reg': '18.9', 'Naive CD4 T-cell activated': '1.9', 'Naive CD8 T-cell activated': '2.2', 'Naive T-reg': '5.7'}
|
3NRX, 3NRY, 4L3I, 4L6Y, 5KMG, 7VBG
|
{'Adipose Tissue': 4.147858471760798, 'Adrenal Gland': 2.6710627906976745, 'Bladder': 3.1262857142857143, 'Blood': 13.149674854682454, 'Blood Vessel': 5.947328838951311, 'Brain': 4.31794242997729, 'Breast': 4.309821350762528, 'Cervix Uteri': 4.6506842105263155, 'Colon': 4.7497498074454425, 'Esophagus': 8.736843598615916, 'Fallopian Tube': 4.434555555555556, 'Heart': 1.5854587340301975, 'Kidney': 1.5213134831460673, 'Liver': 1.0593992477876106, 'Lung': 6.157918685121107, 'Muscle': 1.129561892901619, 'Nerve': 5.434959612277868, 'Ovary': 6.205122222222222, 'Pancreas': 1.7725213414634144, 'Pituitary': 2.0718671378091873, 'Prostate': 2.9573167346938773, 'Salivary Gland': 5.272641975308642, 'Skin': 25.474678828081817, 'Small Intestine': 6.994807486631016, 'Spleen': 6.059149377593362, 'Stomach': 4.9196, 'Testis': 37.2926648199446, 'Thyroid': 3.203790045941807, 'Uterus': 4.478767605633803, 'Vagina': 9.09873076923077}
|
H2AC4
|
MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
|
Homo sapiens
|
Nucleus, Chromosome
|
Tissue enhanced (bone)
|
{'Ciliated cells': '0.2', 'Basal respiratory cells': '0.0', 'Club cells': '0.3', 'Ionocytes': '0.4', 'Mucus glandular cells': '0.4', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '21.8', 'Proximal enterocytes': '1.5', 'Paneth cells': '0.1', 'Distal enterocytes': '2.0', 'Intestinal goblet cells': '0.9', 'Exocrine glandular cells': '-0.052', 'Basal prostatic cells': '0.1', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.016', 'Breast myoepithelial cells': '-0.008', 'Glandular and luminal cells': '1.7', 'Secretory cells': '0.3', 'Basal keratinocytes': '0.7', 'Suprabasal keratinocytes': '0.3', 'Basal squamous epithelial cells': '0.4', 'Squamous epithelial cells': '1.7', 'Alveolar cells type 1': '-0.048', 'Alveolar cells type 2': '-0.318', 'Salivary duct cells': '0.1', 'Ductal cells': '0.124', 'Hepatocytes': '0.057', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.028', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.096', 'Sertoli cells': '-0.302', 'Granulosa cells': '2.0', 'Enteroendocrine cells': '0.1', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.254', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.2', 'Bipolar cells': '0.6', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.4', 'Schwann cells': '-0.023', 'Spermatogonia': '-0.192', 'Spermatocytes': '-0.012', 'Early spermatids': '0.226', 'Late spermatids': '0.333', 'Oocytes': '0.7', 'Cytotrophoblasts': '0.4', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.8', 'Endothelial cells': '0.7', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.015', 'Skeletal myocytes': '-0.049', 'Smooth muscle cells': '0.7', 'Adipocytes': '1.0', 'Melanocytes': '0.074', 'Fibroblasts': '0.5', 'Peritubular cells': '-0.234', 'Endometrial stromal cells': '1.6', 'Ovarian stromal cells': '1.1', 'Undifferentiated cells': '0.7', 'T-cells': '2.4', 'B-cells': '1.5', 'Plasma cells': '12.3', 'Nk-cells': '0.8', 'Granulocytes': '1.8', 'Monocytes': '0.0', 'Macrophages': '1.2', 'Hofbauer cells': '0.6', 'Kupffer cells': '0.2', 'Dendritic cells': '0.8', 'Langerhans cells': '0.004', 'Erythroid cells': '-0.073', 'Adipocytes (Subcutaneous)': '-0.088', 'Adipocytes (Visceral)': '-0.194', 'Breast glandular cells (progenitors)': '-0.079', 'Adipocytes (Breast)': '-0.148', 'Colon enterocytes': '0.038', 'Colon enteroendocrine cells': '-0.065', 'Enteric glia cells': '-0.138', 'Mitotic cells (Colon)': '0.156', 'Mitotic cells (Heart)': '0.010', 'Podocytes': '-0.125', 'Ascending Loop of Henle cells': '0.019', 'Intercalated cells': '-0.263', 'Cholangiocyte': '0.212', 'NK-cells (Liver)': '-0.053', 'Respiratory ciliated cells': '0.007', 'Mitotic cells (Lung)': '0.008', 'NK-cells (Lung)': '0.238', 'B-cells (Lung)': '0.187', 'Alpha cells': '0.033', 'Beta cells': '0.022', 'Prostate glandular cells': '-0.003', 'Prostate basal glandular cells': '0.120', 'Urothelial cells': '0.177', 'Keratinocyte (other)': '0.013', 'Keratinocyte (granular)': '-0.355', 'Hair cortex cells': '0.209', 'Inner root sheath cells': '0.212', 'Outer root sheath cells': '0.314', 'Sebaceous gland cells': '-0.068', 'Eccrine sweat gland cells': '0.088', 'Adipocytes (Skin)': '-0.108', 'Mitotic cells (Skin)': '0.173', 'Parietal cells': '-0.073', 'Chief cells': '-0.108', 'Gastric mucous cells': '0.063', 'Gastric enteroendocrine cells': '-0.051', 'Mitotic cells (Stomach)': '0.205', 'Parafollicular cells': '-0.043', 'Thyroid glandular cells': '-0.033', 'Mitotic cells (Thyroid)': '0.083', 'Adrenal cortex cells': '0.179', 'Adrenal medulla cells': '0.011', 'Mitotic cells (Adrenal gland)': '0.130', 'Minor salivary glandular cells': '-0.116', 'Minor salivary gland ductal cells': '-0.257', 'Minor salivary gland basal cells': '0.135', 'Mitotic cells (Minor salivary gland)': '0.143', 'Adipocytes (Minor salivary gland)': '0.038', 'Somatotropes': '-0.103', 'Lactotropes': '-0.121', 'Gonadotropes': '0.015', 'Corticotropes': '-0.153', 'Thyrotropes': '-0.183', 'Undifferentiated cells (Pituitary gland)': '0.132', 'Mitotic cells (Spleen)': '0.350', 'Platelets': '-0.019', 'Erythrocytes': '0.119', 'Hematopoietic stem cells': '0.046', 'B-cells (Spleen)': '-0.121', 'NK-cells (Spleen)': '-0.018', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.0', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.0', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '0.0', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.3', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.0', 'Oligodendrocyte': '0.0', 'Oligodendrocyte precursor cell': '0.0', 'Endothelial cell': '0.1', 'Pericyte': '0.1', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.0', 'Leukocyte': '0.2', 'Basophil': '0.0', 'Eosinophil': '1.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.1', 'MAIT T-cell': '0.1', 'Memory CD4 T-cell': '0.4', 'Naive CD4 T-cell': '0.2', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '0.6', 'Memory B-cell': '1.5', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.3', 'Myeloid DC': '0.0', 'NK-cell': '1.1', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.3', 'Memory CD4 T-cell TFH': '1.1', 'Memory CD4 T-cell Th2': '1.3', 'Memory CD4 T-cell Th17': '0.9', 'Memory CD4 T-cell Th1\\/Th17': '0.6', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '1.1', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.6', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Switched memory B-cell': '0.0', 'Plasmablast': '1.2', 'Non-switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.1', 'Memory T-reg': '1.6', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.8'}
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2CV5, 2RVQ, 3A6N, 3AFA, 3AN2, 3AV1, 3AV2, 3AYW, 3AZE, 3AZF, 3AZG, 3AZH, 3AZI, 3AZJ, 3AZK, 3AZL, 3AZM, 3AZN, 3W96, 3W97, 3W98, 3W99, 3WKJ, 3WTP, 3X1S, 3X1V, 4YM5, 4YM6, 4Z5T, 5AV5, 5AV6, 5AV8, 5AV9, 5AVB, 5AVC, 5AY8, 5B0Y, 5B0Z, 5B24, 5B2I, 5B2J, 5B31, 5B32, 5B40, 5CPI, 5CPJ, 5CPK, 5GSE, 5GTC, 5GXQ, 5JRG, 5X7X, 5XF3, 5XF4, 5XF5, 5Y0C, 5Y0D, 5Z23, 5ZBX, 6A5L, 6A5O, 6A5P, 6A5R, 6A5T, 6A5U, 6ACL, 6AEE, 6BUZ, 6E0C, 6E0P, 6HKT, 6HTS, 6INQ, 6IPU, 6IQ4, 6IR9, 6J4W, 6J4X, 6J4Y, 6J4Z, 6J50, 6J51, 6JR0, 6JR1, 6JXD, 6KE9, 6KXV, 6L49, 6L4A, 6L9H, 6L9Z, 6LA2, 6LA8, 6LA9, 6LAB, 6LE9, 6LER, 6M3V, 6M44, 6O1D, 6R8Y, 6R8Z, 6R90, 6R91, 6R92, 6R93, 6R94, 6T79, 6T7A, 6T7B, 6T7C, 6T7D, 6T90, 6T93, 6USJ, 6V2K, 6V92, 6YOV, 7BWD, 7BXT, 7BY0, 7C0M, 7CCQ, 7CCR, 7COW, 7D1Z, 7D20, 7DBP, 7K5X, 7K5Y, 7K60, 7K61, 7K63, 7LYA, 7LYB, 7LYC, 7NL0, 7PET, 7PEU, 7PEV, 7PEW, 7PEX, 7PEY, 7PEZ, 7PF0, 7PF2, 7PF3, 7PF4, 7PF5, 7PF6, 7PFA, 7PFC, 7PFD, 7PFE, 7PFF, 7PFT, 7PFU, 7PFV, 7PFW, 7PFX, 7SCY, 7SCZ, 7V90, 7V96, 7V99, 7V9C, 7V9J, 7V9K, 7V9S, 7VA4, 7VCL, 7VZ4, 7W9V, 7WBV, 7WBW, 7WBX, 7XCR, 7XCT, 7XD0, 7XD1, 7XSE, 7XSX, 7XSZ, 7XT7, 7XTD, 7XTI, 7XVL, 7XVM, 7XX5, 7XX6, 7XZX, 7XZY, 7XZZ, 7Y00, 7Y7I, 7ZI4, 8G57, 8GRM, 8H0V, 8H0W, 8HAG, 8HAH, 8HAI, 8HAJ, 8HAK, 8HAL, 8HAM, 8HAN, 8HE5, 8HQY, 8HR1, 8I17, 8IEG, 8IEJ, 8IHL, 8JBX, 8JCC, 8JCD, 8JH2, 8JH3, 8JH4, 8JHG, 8JL9, 8JLA, 8JLB, 8JLD, 8JND, 8JNE, 8JNF, 8KB5, 8OSJ, 8OSK, 8OSL, 8OTS, 8OTT, 8Q36, 8Q3E, 8Q3M, 8Q3X, 8SMW, 8SMX, 8SMY, 8SMZ, 8SN0, 8SN1, 8SN2, 8SN3, 8SN4, 8SN5, 8SN6, 8SN7, 8SN8, 8SN9, 8SNA, 8TXV, 8TXW, 8TXX, 8U13, 8U14, 8UPF, 8UQ8, 8UQ9, 8UQA, 8UQB, 8UQC, 8UQD, 8UQE, 8W9D, 8W9E, 8W9F, 8WG5, 8XBT, 8XBU, 8YTI
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{}
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|
[0.66, 0.73, 0.87, 0.66, 0.4, 0.37, 0.61, 0.43, 0.49, 0.59, 0.51, 0.65, 0.43, 0.61, 0.38, 0.57, 0.65, 0.47, 0.39, 0.52, 0.54, 0.32, 0.58, 0.56, 0.41, 0.1, 0.46, 0.87, 0.66, 0.68, 0.15, 0.55, 0.64, 0.59, 0.43, 0.11, 0.61, 0.59, 0.4, 0.32, 0.51, 0.53, 0.33, 0.57, 0.58, 0.59, 0.33, 0.59, 0.46, 0.56, 0.5, 0.44, 0.5, 0.49, 0.63, 0.56, 0.51, 0.43, 0.46, 0.4, 0.21, 0.45, 0.67, 0.55, 0.17, 0.49, 0.7, 0.23, 0.11, 0.4, 0.56, 0.09, 0.33, 0.67, 0.27, 0.04, 0.55, 0.52, 0.04, 0.06, 0.65, 0.29, 0.01, 0.73, 0.33, 0.9, 0.61, 0.39, 0.82, 0.49, 0.86, 0.67, 0.98, 0.41, 0.65, 0.45, 0.55, 0.38, 0.14, 0.09, 0.55, 0.31, 0.02, 0.44, 0.53, 0.21, 0.02, 0.54, 0.48, 0.04, 0.48, 0.56, 0.3, 0.24, 0.62, 0.48, 0.1, 0.3, 0.56, 0.32, 0.02, 0.57, 0.52, 0.08, 0.29, 0.49, 0.24, 0.03, 0.5, 0.52, 0.03, 0.02, 0.55, 0.25, 0.01, 0.72, 0.47, 0.88, 0.6, 0.3, 0.96, 0.17, 0.53, 0.55, 0.74, 0.47, 0.11, 0.02, 0.17, 0.52, 0.66, 0.43, 0.0, 0.43, 0.52, 0.01, 0.33, 0.66, 0.3, 0.0, 0.44, 0.49, 0.09, 0.46, 0.61, 0.35, 0.24, 0.56, 0.6, 0.13, 0.31, 0.72, 0.34, 0.0, 0.36, 0.49, 0.1, 0.09, 0.72, 0.39, 0.0, 0.32, 0.54, 0.07, 0.04, 0.57, 0.31, 0.12, 0.46, 0.31, 0.89, 0.25, 0.67, 0.51, 0.56, 0.24, 0.08, 0.43, 0.43, 0.0, 0.28, 0.72, 0.61, 0.78, 0.36, 0.7, 0.73, 0.09, 0.37, 0.05, 0.13, 0.63, 0.75, 0.26, 0.07, 0.47, 0.34, 0.0, 0.29, 0.59, 0.11, 0.11, 0.54, 0.56, 0.05, 0.45, 0.55, 0.43, 0.43, 0.49, 0.55, 0.19, 0.41, 0.62, 0.38, 0.0, 0.36, 0.43, 0.09, 0.04, 0.39, 0.36, 0.0, 0.38, 0.62, 0.05, 0.09, 0.62, 0.58, 0.23, 0.82, 0.1, 0.49, 0.61, 0.75, 0.43, 0.21, 0.67, 0.63, 0.16, 0.44, 0.71, 0.23, 0.19, 0.6, 0.51, 0.17, 0.36, 0.47, 0.75, 0.19, 0.4, 0.69, 0.28, 0.0, 0.44, 0.64, 0.1, 0.04, 0.48, 0.46, 0.0, 0.38, 0.48, 0.32, 0.2, 0.32, 0.48, 0.42, 0.15, 0.28, 0.7, 0.46, 0.0, 0.43, 0.48, 0.08, 0.11, 0.64, 0.35, 0.0, 0.35, 0.56, 0.2, 0.03, 0.51, 0.32, 0.03, 0.14, 0.13, 0.13, 0.63, 0.76, 0.37, 0.22, 0.63, 0.71, 0.11, 0.66, 0.24, 0.28, 0.83, 0.29, 0.79, 0.71, 0.17, 0.43, 0.45, 0.54, 0.07, 0.2, 0.59, 0.49, 0.0, 0.41, 0.56, 0.14, 0.05, 0.56, 0.49, 0.0, 0.32, 0.57, 0.27, 0.13, 0.6, 0.82, 0.11, 0.31, 0.64, 0.06, 0.03, 0.51, 0.14, 0.02, 0.4, 0.46, 0.0, 0.25, 0.51, 0.1, 0.02, 0.57, 0.46, 0.0, 0.37, 0.33, 0.11, 0.06, 0.68, 0.39, 0.34, 0.36, 0.43, 0.81, 0.63, 0.13, 0.79, 0.75, 0.69, 0.95, 0.79, 0.65, 0.43, 0.37, 0.62, 0.63, 0.15, 0.32, 0.66, 0.46, 0.22, 0.37, 0.61, 0.09, 0.47, 0.72, 0.35, 0.0, 0.39, 0.66, 0.08, 0.13, 0.68, 0.41, 0.03, 0.45, 0.54, 0.34, 0.06, 0.46, 0.61, 0.11, 0.35, 0.7, 0.85, 0.38, 0.79, 0.69, 0.35, 0.02, 0.5, 0.12, 0.61, 0.56, 0.33, 0.43, 0.03, 0.35, 0.44, 0.32, 0.04, 0.52, 0.5, 0.27, 0.26, 0.39, 0.59, 0.18, 0.61, 0.48, 0.49, 0.36, 0.4, 0.54, 0.36, 0.45, 0.59, 0.51, 0.55, 0.57, 0.5, 0.54, 0.59, 0.54, 0.57, 0.52, 0.48, 0.47, 0.47, 0.41, 0.79, 0.9, 0.87, 0.5, 0.6, 0.81, 0.76, 0.91, 0.84, 0.92, 0.97, 0.97, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.93, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.95, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 0.96, 0.95, 0.86, 0.86, 0.84, 0.81, 0.82, 0.93, 0.84, 0.96, 0.84, 0.78, 0.84, 0.74, 0.66, 0.78, 0.73, 0.61, 0.79, 0.83, 0.84, 0.89, 0.81, 0.95, 0.86, 1.0, 0.76, 0.9, 0.89, 0.8, 0.9, 0.88, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0]
|
[57.8, 60.38, 60.51, 60.93, 58.12, 58.02, 56.76, 55.08, 61.18, 67.07, 73.67, 76.01, 81.5, 84.25, 88.92, 92.73, 95.52, 96.35, 97.95, 96.88, 96.63, 97.37, 97.75, 98.41, 98.34, 98.44, 98.35, 98.59, 97.96, 98.35, 98.29, 98.18, 97.91, 98.19, 97.68, 96.43, 97.29, 96.94, 95.25, 94.44, 95.06, 95.52, 96.96, 96.72, 97.08, 95.19, 97.64, 98.24, 98.43, 98.6, 98.72, 98.57, 98.74, 98.79, 98.64, 98.67, 98.73, 98.24, 98.35, 98.6, 98.41, 98.31, 98.65, 98.6, 98.52, 98.71, 98.78, 98.73, 98.55, 98.38, 98.73, 98.44, 97.54, 96.91, 98.06, 98.28, 97.27, 98.68, 98.68, 98.36, 98.62, 98.42, 98.66, 98.48, 98.43, 98.11, 98.23, 98.34, 98.01, 97.05, 97.98, 97.8, 97.98, 98.25, 97.79, 97.94, 97.85, 97.44, 95.06, 95.78, 96.81, 97.2, 97.41, 98.09, 97.96, 97.65, 96.49, 96.08, 95.55, 94.36, 95.1, 95.6, 94.15, 93.56, 95.17, 94.54, 93.6, 92.38, 85.76, 81.37, 75.6, 71.63, 65.82, 60.32, 59.55, 56.1, 60.09, 57.15, 53.86, 50.78]
|
[1.0, 0.82, 0.94, 0.91, 0.71, 0.98, 0.9, 0.8, 0.86, 0.89, 0.88, 0.93, 0.89, 0.92, 0.86, 0.71, 0.59, 0.41, 0.12, 0.55, 0.74, 0.4, 0.73, 0.15, 0.87, 0.3, 0.35, 0.0, 0.41, 0.57, 0.12, 0.19, 0.71, 0.58, 0.18, 0.53, 0.78, 0.43, 0.74, 0.75, 0.55, 0.98, 0.93, 0.18, 0.59, 0.67, 0.58, 0.42, 0.0, 0.35, 0.71, 0.38, 0.0, 0.34, 0.35, 0.42, 0.2, 0.65, 0.33, 0.36, 0.51, 0.38, 0.22, 0.51, 0.62, 0.29, 0.0, 0.34, 0.4, 0.11, 0.03, 0.77, 0.76, 0.46, 0.89, 0.61, 0.99, 0.8, 0.39, 0.52, 0.37, 0.3, 0.02, 0.27, 0.09, 0.2, 0.08, 0.06, 0.2, 0.65, 0.27, 0.84, 0.74, 0.04, 0.37, 0.85, 0.64, 0.24, 0.59, 0.98, 0.51, 0.93, 0.21, 0.74, 0.85, 0.02, 0.66, 0.76, 0.35, 0.82, 0.75, 0.74, 0.61, 0.68, 0.89, 0.74, 0.6, 0.94, 0.92, 0.95, 0.9, 0.83, 0.74, 0.84, 0.85, 0.86, 0.85, 0.9, 0.86, 0.98]
| null | null | null | null |
RACGAP1,CENPE,KIF4A,KIF23 ,KIF14 , KIF20A ,PLK1 ,KIF20B
| null | null | null | null |
Homodimer
| null | 78.712903
| 0.544032
| 90.834231
| 0.568231
| 2,087
|
O43663
|
P0C0S5
|
22199232, E3Net
|
UbiNet, UbiBrowser, 31181401
|
PRC1
|
MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSFERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAPFCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGNLLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKERAKQERQLKNKKQTETEMLYGSAPRTPSKRRGLAPNTPGKARKLNTTTMSNATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPRTGRHGANKENLELNGSILSGGYPGSAPLQRNFSINSVASTYSEFAKDPSLSDSSTVGLQRELSKASKSDATSGILNSTNIQS
|
Homo sapiens
|
Nucleus, Cytoplasm, Cytoplasm, cytoskeleton, spindle pole, Midbody, Chromosome
|
Tissue enhanced (bone marrow, testis)
|
{'Ciliated cells': '1.9', 'Basal respiratory cells': '4.0', 'Club cells': '2.6', 'Ionocytes': '4.4', 'Mucus glandular cells': '2.0', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '0.6', 'Paneth cells': '4.4', 'Distal enterocytes': '1.4', 'Intestinal goblet cells': '8.6', 'Exocrine glandular cells': '-0.424', 'Basal prostatic cells': '0.4', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.512', 'Breast myoepithelial cells': '0.489', 'Glandular and luminal cells': '5.6', 'Secretory cells': '2.3', 'Basal keratinocytes': '13.6', 'Suprabasal keratinocytes': '9.0', 'Basal squamous epithelial cells': '8.2', 'Squamous epithelial cells': '24.9', 'Alveolar cells type 1': '-0.119', 'Alveolar cells type 2': '-0.065', 'Salivary duct cells': '2.2', 'Ductal cells': '0.452', 'Hepatocytes': '0.350', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.169', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.038', 'Sertoli cells': '-0.086', 'Granulosa cells': '6.8', 'Enteroendocrine cells': '4.0', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '-0.137', 'Excitatory neurons': '4.8', 'Inhibitory neurons': '5.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.5', 'Bipolar cells': '1.4', 'Horizontal cells': '0.6', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '1.6', 'Microglial cells': '1.8', 'Muller glia cells': '1.0', 'Schwann cells': '0.155', 'Spermatogonia': '0.356', 'Spermatocytes': '0.840', 'Early spermatids': '0.496', 'Late spermatids': '0.109', 'Oocytes': '73.5', 'Cytotrophoblasts': '23.6', 'Syncytiotrophoblasts': '9.7', 'Extravillous trophoblasts': '35.1', 'Endothelial cells': '2.1', 'Lymphatic endothelial cells': '3.2', 'Cardiomyocytes': '0.491', 'Skeletal myocytes': '0.090', 'Smooth muscle cells': '5.3', 'Adipocytes': '2.0', 'Melanocytes': '0.520', 'Fibroblasts': '4.4', 'Peritubular cells': '-0.165', 'Endometrial stromal cells': '2.7', 'Ovarian stromal cells': '2.7', 'Undifferentiated cells': '30.0', 'T-cells': '4.1', 'B-cells': '3.2', 'Plasma cells': '15.9', 'Nk-cells': '3.5', 'Granulocytes': '0.2', 'Monocytes': '3.9', 'Macrophages': '4.6', 'Hofbauer cells': '9.7', 'Kupffer cells': '3.6', 'Dendritic cells': '1.6', 'Langerhans cells': '0.161', 'Erythroid cells': '0.185', 'Adipocytes (Subcutaneous)': '-0.201', 'Adipocytes (Visceral)': '-0.143', 'Breast glandular cells (progenitors)': '0.409', 'Adipocytes (Breast)': '-0.476', 'Colon enterocytes': '0.263', 'Colon enteroendocrine cells': '0.079', 'Enteric glia cells': '-0.225', 'Mitotic cells (Colon)': '0.541', 'Mitotic cells (Heart)': '0.604', 'Podocytes': '-0.159', 'Ascending Loop of Henle cells': '0.380', 'Intercalated cells': '-0.085', 'Cholangiocyte': '0.398', 'NK-cells (Liver)': '-0.195', 'Respiratory ciliated cells': '0.056', 'Mitotic cells (Lung)': '0.656', 'NK-cells (Lung)': '0.131', 'B-cells (Lung)': '0.145', 'Alpha cells': '0.302', 'Beta cells': '0.192', 'Prostate glandular cells': '-0.169', 'Prostate basal glandular cells': '0.149', 'Urothelial cells': '0.144', 'Keratinocyte (other)': '0.346', 'Keratinocyte (granular)': '-0.148', 'Hair cortex cells': '0.062', 'Inner root sheath cells': '0.191', 'Outer root sheath cells': '0.198', 'Sebaceous gland cells': '-0.036', 'Eccrine sweat gland cells': '-0.063', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.827', 'Parietal cells': '0.011', 'Chief cells': '-0.010', 'Gastric mucous cells': '0.442', 'Gastric enteroendocrine cells': '0.080', 'Mitotic cells (Stomach)': '0.781', 'Parafollicular cells': '0.050', 'Thyroid glandular cells': '0.042', 'Mitotic cells (Thyroid)': '0.436', 'Adrenal cortex cells': '0.466', 'Adrenal medulla cells': '0.134', 'Mitotic cells (Adrenal gland)': '0.879', 'Minor salivary glandular cells': '0.283', 'Minor salivary gland ductal cells': '-0.271', 'Minor salivary gland basal cells': '0.742', 'Mitotic cells (Minor salivary gland)': '0.849', 'Adipocytes (Minor salivary gland)': '0.243', 'Somatotropes': '-0.356', 'Lactotropes': '-0.338', 'Gonadotropes': '-0.061', 'Corticotropes': '-0.240', 'Thyrotropes': '-0.112', 'Undifferentiated cells (Pituitary gland)': '0.421', 'Mitotic cells (Spleen)': '0.927', 'Platelets': '0.103', 'Erythrocytes': '0.359', 'Hematopoietic stem cells': '0.419', 'B-cells (Spleen)': '-0.133', 'NK-cells (Spleen)': '-0.200', 'Amygdala excitatory': '2.4', 'Cerebellar inhibitory': '3.3', 'Cge interneuron': '3.1', 'Deep-layer corticothalamic and 6b': '3.4', 'Deep-layer intratelencephalic': '2.7', 'Deep-layer near-projecting': '2.7', 'Eccentric medium spiny neuron': '2.1', 'Hippocampal ca1-3': '3.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '2.8', 'Lamp5-lhx6 and chandelier': '2.9', 'Lower rhombic lip': '4.3', 'Mammillary body': '2.9', 'Medium spiny neuron': '2.1', 'Mge interneuron': '3.2', 'Midbrain-derived inhibitory': '3.4', 'Miscellaneous': '3.2', 'Splatter': '4.2', 'Thalamic excitatory': '3.6', 'Upper rhombic lip': '6.7', 'Upper-layer intratelencephalic': '2.4', 'Astrocyte': '1.9', 'Bergmann glia': '0.9', 'Central nervous system macrophage': '1.0', 'Choroid plexus epithelial cell': '1.9', 'Committed oligodendrocyte precursor': '1.2', 'Ependymal cell': '1.4', 'Oligodendrocyte': '1.6', 'Oligodendrocyte precursor cell': '1.4', 'Endothelial cell': '0.5', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '2.9', 'Fibroblast': '1.0', 'Leukocyte': '2.1', 'Basophil': '19.3', 'Eosinophil': '2.9', 'Neutrophil': '0.4', 'Classical monocyte': '9.4', 'Non-classical monocyte': '2.0', 'Intermediate monocyte': '1.7', 'T-reg': '9.6', 'GdT-cell': '0.6', 'MAIT T-cell': '5.1', 'Memory CD4 T-cell': '1.3', 'Naive CD4 T-cell': '3.9', 'Memory CD8 T-cell': '1.3', 'Naive CD8 T-cell': '3.0', 'Memory B-cell': '1.1', 'Naive B-cell': '7.6', 'Plasmacytoid DC': '7.2', 'Myeloid DC': '20.8', 'NK-cell': '5.5', 'Total PBMC': '5.6', 'Vd2 gdTCR': '5.9', 'Memory CD4 T-cell Th1\\/Th17': '5.8', 'Memory CD4 T-cell Th17': '8.8', 'Memory CD4 T-cell Th2': '10.5', 'Non-Vd2 gdTCR': '6.8', 'Memory CD4 T-cell Th1': '7.1', 'Memory CD4 T-cell TFH': '7.0', 'Terminal effector memory CD4 T-cell': '3.2', 'Central memory CD8 T-cell': '6.7', 'Effector memory CD8 T-cell': '11.4', 'Terminal effector memory CD8 T-cell': '4.9', 'Non-switched memory B-cell': '5.4', 'Plasmablast': '30.3', 'Switched memory B-cell': '9.2', 'Exhausted memory B-cell': '12.2', 'Progenitor cell': '8.9', 'Memory T-reg': '18.9', 'Naive CD4 T-cell activated': '1.9', 'Naive CD8 T-cell activated': '2.2', 'Naive T-reg': '5.7'}
|
3NRX, 3NRY, 4L3I, 4L6Y, 5KMG, 7VBG
|
{'Adipose Tissue': 4.147858471760798, 'Adrenal Gland': 2.6710627906976745, 'Bladder': 3.1262857142857143, 'Blood': 13.149674854682454, 'Blood Vessel': 5.947328838951311, 'Brain': 4.31794242997729, 'Breast': 4.309821350762528, 'Cervix Uteri': 4.6506842105263155, 'Colon': 4.7497498074454425, 'Esophagus': 8.736843598615916, 'Fallopian Tube': 4.434555555555556, 'Heart': 1.5854587340301975, 'Kidney': 1.5213134831460673, 'Liver': 1.0593992477876106, 'Lung': 6.157918685121107, 'Muscle': 1.129561892901619, 'Nerve': 5.434959612277868, 'Ovary': 6.205122222222222, 'Pancreas': 1.7725213414634144, 'Pituitary': 2.0718671378091873, 'Prostate': 2.9573167346938773, 'Salivary Gland': 5.272641975308642, 'Skin': 25.474678828081817, 'Small Intestine': 6.994807486631016, 'Spleen': 6.059149377593362, 'Stomach': 4.9196, 'Testis': 37.2926648199446, 'Thyroid': 3.203790045941807, 'Uterus': 4.478767605633803, 'Vagina': 9.09873076923077}
|
H2AZ1
|
MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV
|
Homo sapiens
|
Nucleus, Chromosome
|
Tissue enhanced (bone)
|
{'Ciliated cells': '266.9', 'Basal respiratory cells': '902.9', 'Club cells': '365.0', 'Ionocytes': '519.5', 'Mucus glandular cells': '215.5', 'Serous glandular cells': '204.5', 'Gastric mucus-secreting cells': '234.6', 'Proximal enterocytes': '185.9', 'Paneth cells': '224.9', 'Distal enterocytes': '224.1', 'Intestinal goblet cells': '338.2', 'Exocrine glandular cells': '-0.657', 'Basal prostatic cells': '207.5', 'Prostatic glandular cells': '139.4', 'Breast glandular cells': '0.243', 'Breast myoepithelial cells': '0.147', 'Glandular and luminal cells': '305.3', 'Secretory cells': '212.9', 'Basal keratinocytes': '1203.8', 'Suprabasal keratinocytes': '911.1', 'Basal squamous epithelial cells': '997.0', 'Squamous epithelial cells': '920.5', 'Alveolar cells type 1': '0.017', 'Alveolar cells type 2': '-0.164', 'Salivary duct cells': '239.2', 'Ductal cells': '0.588', 'Hepatocytes': '0.484', 'Cholangiocytes': '164.1', 'Proximal tubular cells': '0.185', 'Distal tubular cells': '328.9', 'Collecting duct cells': '190.6', 'Mesothelial cells': '0.053', 'Sertoli cells': '-0.179', 'Granulosa cells': '328.3', 'Enteroendocrine cells': '295.3', 'Pancreatic endocrine cells': '597.7', 'Leydig cells': '-0.119', 'Excitatory neurons': '36.7', 'Inhibitory neurons': '33.9', 'Cone photoreceptor cells': '207.3', 'Rod photoreceptor cells': '172.3', 'Bipolar cells': '187.6', 'Horizontal cells': '72.4', 'Astrocytes': '14.9', 'Oligodendrocyte precursor cells': '14.1', 'Oligodendrocytes': '23.8', 'Microglial cells': '27.7', 'Muller glia cells': '200.6', 'Schwann cells': '0.207', 'Spermatogonia': '0.033', 'Spermatocytes': '0.525', 'Early spermatids': '0.494', 'Late spermatids': '0.077', 'Oocytes': '97.8', 'Cytotrophoblasts': '713.5', 'Syncytiotrophoblasts': '432.7', 'Extravillous trophoblasts': '1564.7', 'Endothelial cells': '371.7', 'Lymphatic endothelial cells': '222.0', 'Cardiomyocytes': '0.517', 'Skeletal myocytes': '-0.102', 'Smooth muscle cells': '346.8', 'Adipocytes': '627.5', 'Melanocytes': '0.282', 'Fibroblasts': '363.1', 'Peritubular cells': '-0.180', 'Endometrial stromal cells': '221.6', 'Ovarian stromal cells': '369.9', 'Undifferentiated cells': '884.0', 'T-cells': '514.0', 'B-cells': '427.5', 'Plasma cells': '793.0', 'Nk-cells': '345.5', 'Granulocytes': '279.2', 'Monocytes': '480.7', 'Macrophages': '475.8', 'Hofbauer cells': '675.0', 'Kupffer cells': '258.0', 'Dendritic cells': '242.5', 'Langerhans cells': '0.064', 'Erythroid cells': '-0.023', 'Adipocytes (Subcutaneous)': '-0.281', 'Adipocytes (Visceral)': '-0.283', 'Breast glandular cells (progenitors)': '0.097', 'Adipocytes (Breast)': '-0.252', 'Colon enterocytes': '-0.151', 'Colon enteroendocrine cells': '0.030', 'Enteric glia cells': '-0.221', 'Mitotic cells (Colon)': '-0.163', 'Mitotic cells (Heart)': '0.526', 'Podocytes': '-0.007', 'Ascending Loop of Henle cells': '0.348', 'Intercalated cells': '-0.042', 'Cholangiocyte': '0.415', 'NK-cells (Liver)': '-0.314', 'Respiratory ciliated cells': '-0.028', 'Mitotic cells (Lung)': '0.221', 'NK-cells (Lung)': '0.197', 'B-cells (Lung)': '0.026', 'Alpha cells': '0.406', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.276', 'Prostate basal glandular cells': '0.013', 'Urothelial cells': '-0.042', 'Keratinocyte (other)': '0.101', 'Keratinocyte (granular)': '-0.186', 'Hair cortex cells': '0.191', 'Inner root sheath cells': '0.276', 'Outer root sheath cells': '0.294', 'Sebaceous gland cells': '0.128', 'Eccrine sweat gland cells': '-0.001', 'Adipocytes (Skin)': '-0.081', 'Mitotic cells (Skin)': '0.524', 'Parietal cells': '-0.594', 'Chief cells': '-0.466', 'Gastric mucous cells': '-0.137', 'Gastric enteroendocrine cells': '-0.372', 'Mitotic cells (Stomach)': '0.346', 'Parafollicular cells': '0.057', 'Thyroid glandular cells': '0.192', 'Mitotic cells (Thyroid)': '0.092', 'Adrenal cortex cells': '0.487', 'Adrenal medulla cells': '0.198', 'Mitotic cells (Adrenal gland)': '0.582', 'Minor salivary glandular cells': '0.489', 'Minor salivary gland ductal cells': '-0.140', 'Minor salivary gland basal cells': '0.477', 'Mitotic cells (Minor salivary gland)': '0.527', 'Adipocytes (Minor salivary gland)': '0.104', 'Somatotropes': '0.342', 'Lactotropes': '0.055', 'Gonadotropes': '-0.251', 'Corticotropes': '-0.139', 'Thyrotropes': '-0.118', 'Undifferentiated cells (Pituitary gland)': '-0.088', 'Mitotic cells (Spleen)': '0.475', 'Platelets': '0.070', 'Erythrocytes': '0.102', 'Hematopoietic stem cells': '0.161', 'B-cells (Spleen)': '0.016', 'NK-cells (Spleen)': '-0.109', 'Amygdala excitatory': '23.7', 'Cerebellar inhibitory': '59.0', 'Cge interneuron': '51.5', 'Deep-layer corticothalamic and 6b': '39.3', 'Deep-layer intratelencephalic': '36.1', 'Deep-layer near-projecting': '49.0', 'Eccentric medium spiny neuron': '43.1', 'Hippocampal ca1-3': '31.5', 'Hippocampal ca4': '67.2', 'Hippocampal dentate gyrus': '52.3', 'Lamp5-lhx6 and chandelier': '49.5', 'Lower rhombic lip': '57.7', 'Mammillary body': '26.6', 'Medium spiny neuron': '36.0', 'Mge interneuron': '46.7', 'Midbrain-derived inhibitory': '74.8', 'Miscellaneous': '53.6', 'Splatter': '47.6', 'Thalamic excitatory': '52.1', 'Upper rhombic lip': '74.0', 'Upper-layer intratelencephalic': '44.2', 'Astrocyte': '14.3', 'Bergmann glia': '23.9', 'Central nervous system macrophage': '28.2', 'Choroid plexus epithelial cell': '23.6', 'Committed oligodendrocyte precursor': '29.3', 'Ependymal cell': '20.4', 'Oligodendrocyte': '30.9', 'Oligodendrocyte precursor cell': '25.7', 'Endothelial cell': '52.9', 'Pericyte': '72.3', 'Vascular associated smooth muscle cell': '55.4', 'Fibroblast': '24.3', 'Leukocyte': '49.5', 'Basophil': '177.9', 'Eosinophil': '1379.1', 'Neutrophil': '646.3', 'Classical monocyte': '102.8', 'Non-classical monocyte': '221.0', 'Intermediate monocyte': '308.6', 'T-reg': '283.9', 'GdT-cell': '352.4', 'MAIT T-cell': '154.8', 'Memory CD4 T-cell': '582.7', 'Naive CD4 T-cell': '151.2', 'Memory CD8 T-cell': '475.7', 'Naive CD8 T-cell': '134.6', 'Memory B-cell': '495.9', 'Naive B-cell': '71.2', 'Plasmacytoid DC': '219.8', 'Myeloid DC': '199.8', 'NK-cell': '119.3', 'Total PBMC': '331.7', 'Vd2 gdTCR': '211.5', 'Memory CD4 T-cell Th1\\/Th17': '180.7', 'Memory CD4 T-cell Th17': '166.9', 'Memory CD4 T-cell Th2': '180.6', 'Non-Vd2 gdTCR': '191.3', 'Memory CD4 T-cell Th1': '141.7', 'Memory CD4 T-cell TFH': '126.0', 'Terminal effector memory CD4 T-cell': '181.2', 'Central memory CD8 T-cell': '202.3', 'Effector memory CD8 T-cell': '196.8', 'Terminal effector memory CD8 T-cell': '240.4', 'Non-switched memory B-cell': '141.7', 'Plasmablast': '452.9', 'Switched memory B-cell': '166.1', 'Exhausted memory B-cell': '238.9', 'Progenitor cell': '137.9', 'Memory T-reg': '136.4', 'Naive CD4 T-cell activated': '135.2', 'Naive CD8 T-cell activated': '108.6', 'Naive T-reg': '121.7'}
|
1F66, 3WA9, 4CAY, 4NFT, 5B31, 5B32, 5B33, 5CHL, 5FUG, 5Z30, 6JOU, 6KO2, 7YRD, 7YRG, 8JHF, 8T9F, 8THU
|
{}
|
[53.31, 74.6, 84.9, 86.04, 86.7, 89.37, 90.52, 89.38, 90.34, 91.81, 90.92, 93.47, 92.96, 92.84, 93.07, 92.97, 93.93, 93.17, 93.0, 91.94, 93.2, 92.1, 90.25, 91.99, 91.73, 92.97, 90.53, 90.39, 91.87, 89.43, 86.6, 90.67, 89.69, 88.59, 90.26, 90.54, 92.47, 91.85, 92.77, 92.34, 93.32, 93.95, 94.05, 93.53, 95.54, 94.55, 94.53, 94.39, 95.31, 95.37, 95.64, 96.6, 96.11, 95.9, 95.97, 95.93, 94.59, 94.69, 95.43, 95.74, 94.61, 94.39, 95.1, 95.19, 94.64, 94.21, 95.36, 94.77, 93.77, 94.02, 95.25, 93.77, 92.64, 94.09, 95.0, 94.04, 92.23, 93.32, 93.85, 91.74, 90.84, 92.4, 91.18, 87.45, 87.28, 84.44, 75.8, 76.23, 71.15, 69.55, 65.13, 67.42, 64.22, 73.94, 89.65, 91.58, 91.16, 91.21, 91.78, 92.85, 92.23, 91.29, 92.24, 93.22, 92.95, 92.48, 94.26, 95.21, 94.55, 93.8, 94.87, 95.88, 94.33, 94.56, 94.94, 95.72, 94.88, 93.88, 95.25, 95.94, 95.08, 94.83, 96.14, 96.44, 95.23, 95.55, 96.8, 96.32, 94.91, 94.29, 95.61, 94.89, 93.82, 93.6, 94.71, 93.7, 92.74, 92.22, 90.7, 90.49, 88.75, 86.74, 84.72, 81.18, 83.58, 86.39, 90.41, 91.0, 91.24, 92.02, 92.25, 93.18, 94.33, 95.22, 95.57, 95.85, 97.15, 96.66, 96.17, 97.19, 97.58, 96.98, 96.97, 97.04, 97.74, 96.43, 95.92, 96.5, 96.93, 96.38, 96.12, 96.45, 96.78, 97.06, 96.35, 97.06, 97.19, 96.93, 97.0, 97.69, 97.48, 96.56, 95.98, 95.92, 96.09, 94.34, 93.13, 93.52, 92.18, 92.76, 93.33, 94.74, 92.19, 94.22, 93.29, 94.44, 95.67, 94.59, 93.36, 93.97, 93.5, 90.44, 90.29, 89.13, 88.25, 85.75, 89.2, 90.77, 91.89, 94.8, 94.91, 95.78, 96.09, 95.49, 96.33, 97.47, 97.02, 96.88, 97.79, 97.62, 97.25, 97.9, 97.68, 97.22, 97.05, 97.43, 96.89, 95.64, 95.35, 95.71, 96.05, 94.62, 95.59, 96.53, 96.68, 96.82, 97.17, 97.22, 97.57, 97.31, 96.91, 97.12, 96.66, 95.27, 96.1, 96.16, 96.05, 94.86, 94.43, 94.43, 94.28, 92.57, 94.1, 91.67, 92.41, 91.77, 92.9, 91.23, 90.3, 91.19, 90.29, 88.8, 90.63, 90.15, 89.89, 90.22, 91.46, 92.07, 91.55, 92.35, 94.79, 94.34, 95.32, 96.11, 97.13, 97.02, 97.07, 96.07, 97.36, 97.58, 96.62, 96.45, 95.99, 95.25, 95.31, 94.72, 94.53, 94.9, 94.29, 95.03, 95.85, 95.6, 96.28, 96.69, 96.19, 97.03, 96.67, 96.73, 96.97, 96.64, 96.61, 95.92, 95.3, 94.37, 95.09, 93.91, 91.81, 90.26, 89.31, 89.14, 90.12, 90.84, 90.42, 90.31, 92.92, 92.21, 92.38, 94.08, 92.37, 93.93, 93.04, 90.47, 92.87, 91.03, 92.21, 92.99, 93.01, 91.98, 94.87, 96.19, 95.96, 96.0, 96.83, 97.39, 96.35, 96.91, 96.07, 96.8, 97.1, 95.64, 94.7, 95.34, 94.09, 91.2, 92.93, 93.08, 89.88, 88.37, 90.57, 89.99, 90.56, 91.93, 92.32, 92.09, 92.24, 92.28, 93.34, 94.14, 91.71, 93.54, 94.18, 94.39, 93.75, 92.49, 93.12, 91.9, 91.22, 90.53, 89.33, 87.64, 86.75, 86.27, 83.9, 82.77, 77.04, 78.09, 79.28, 76.15, 72.54, 62.21, 56.53, 65.61, 70.9, 81.59, 83.1, 84.66, 84.94, 88.88, 86.59, 90.34, 90.26, 91.18, 91.7, 92.43, 92.96, 90.97, 92.58, 92.37, 93.47, 93.41, 92.58, 92.68, 93.67, 93.24, 91.99, 92.77, 93.18, 92.81, 90.42, 91.47, 91.63, 90.6, 90.44, 90.91, 90.36, 88.72, 84.62, 86.3, 83.0, 84.79, 85.91, 84.18, 85.74, 82.87, 84.09, 86.86, 89.82, 89.83, 91.4, 91.54, 89.42, 91.78, 92.36, 91.33, 91.83, 92.79, 92.36, 91.27, 90.83, 90.9, 91.71, 89.92, 89.0, 88.7, 89.21, 88.37, 88.2, 88.8, 88.01, 83.63, 85.67, 86.6, 85.99, 82.23, 84.63, 83.4, 80.37, 78.47, 81.09, 78.8, 78.13, 77.08, 75.24, 72.54, 58.17, 56.31, 49.52, 50.84, 46.56, 44.31, 52.78, 41.14, 43.14, 40.63, 39.64, 38.83, 46.21, 44.39, 50.09, 46.93, 51.65, 43.95, 42.7, 44.35, 43.45, 44.27, 43.15, 51.43, 44.92, 39.72, 44.96, 40.71, 43.1, 38.53, 43.03, 41.53, 43.48, 39.1, 41.22, 42.0, 40.8, 42.85, 50.43, 49.85, 41.5, 41.83, 37.27, 35.06, 44.53, 45.16, 46.43, 43.35, 42.9, 56.34, 50.32, 50.66, 43.77, 48.21, 54.42, 50.96, 39.73, 41.79, 42.52, 39.25, 45.93, 36.07, 35.26, 32.22, 34.46, 38.57, 36.64, 44.17, 41.96, 47.32, 42.52, 48.1, 45.04, 41.14, 43.92, 34.45, 37.48, 36.01, 31.14, 32.43, 32.62, 34.91, 31.99, 34.44, 33.73, 32.06, 32.08, 31.98, 32.7, 31.19, 30.76, 38.48, 33.09, 34.84, 33.5, 34.17, 40.17, 30.73, 32.47, 32.45, 30.58, 35.21, 32.34, 34.79, 33.46, 31.33, 34.13, 30.12, 31.1, 32.14, 35.58, 34.7, 37.56, 46.29, 40.25, 52.47, 44.59, 44.36, 45.32, 39.7, 35.96, 40.42, 37.26, 31.13, 32.62, 29.96, 34.06, 30.61, 33.76, 34.02, 34.76, 39.3, 35.91, 36.18, 35.97, 37.91, 40.12, 39.4, 37.6, 39.85, 39.02, 40.68, 39.38, 40.26, 40.13, 41.09, 42.89, 42.37, 43.04, 41.64, 39.92, 43.38, 41.37, 42.12, 44.72, 40.59]
|
[0.66, 0.73, 0.87, 0.66, 0.4, 0.37, 0.61, 0.43, 0.49, 0.59, 0.51, 0.65, 0.43, 0.61, 0.38, 0.57, 0.65, 0.47, 0.39, 0.52, 0.54, 0.32, 0.58, 0.56, 0.41, 0.1, 0.46, 0.87, 0.66, 0.68, 0.15, 0.55, 0.64, 0.59, 0.43, 0.11, 0.61, 0.59, 0.4, 0.32, 0.51, 0.53, 0.33, 0.57, 0.58, 0.59, 0.33, 0.59, 0.46, 0.56, 0.5, 0.44, 0.5, 0.49, 0.63, 0.56, 0.51, 0.43, 0.46, 0.4, 0.21, 0.45, 0.67, 0.55, 0.17, 0.49, 0.7, 0.23, 0.11, 0.4, 0.56, 0.09, 0.33, 0.67, 0.27, 0.04, 0.55, 0.52, 0.04, 0.06, 0.65, 0.29, 0.01, 0.73, 0.33, 0.9, 0.61, 0.39, 0.82, 0.49, 0.86, 0.67, 0.98, 0.41, 0.65, 0.45, 0.55, 0.38, 0.14, 0.09, 0.55, 0.31, 0.02, 0.44, 0.53, 0.21, 0.02, 0.54, 0.48, 0.04, 0.48, 0.56, 0.3, 0.24, 0.62, 0.48, 0.1, 0.3, 0.56, 0.32, 0.02, 0.57, 0.52, 0.08, 0.29, 0.49, 0.24, 0.03, 0.5, 0.52, 0.03, 0.02, 0.55, 0.25, 0.01, 0.72, 0.47, 0.88, 0.6, 0.3, 0.96, 0.17, 0.53, 0.55, 0.74, 0.47, 0.11, 0.02, 0.17, 0.52, 0.66, 0.43, 0.0, 0.43, 0.52, 0.01, 0.33, 0.66, 0.3, 0.0, 0.44, 0.49, 0.09, 0.46, 0.61, 0.35, 0.24, 0.56, 0.6, 0.13, 0.31, 0.72, 0.34, 0.0, 0.36, 0.49, 0.1, 0.09, 0.72, 0.39, 0.0, 0.32, 0.54, 0.07, 0.04, 0.57, 0.31, 0.12, 0.46, 0.31, 0.89, 0.25, 0.67, 0.51, 0.56, 0.24, 0.08, 0.43, 0.43, 0.0, 0.28, 0.72, 0.61, 0.78, 0.36, 0.7, 0.73, 0.09, 0.37, 0.05, 0.13, 0.63, 0.75, 0.26, 0.07, 0.47, 0.34, 0.0, 0.29, 0.59, 0.11, 0.11, 0.54, 0.56, 0.05, 0.45, 0.55, 0.43, 0.43, 0.49, 0.55, 0.19, 0.41, 0.62, 0.38, 0.0, 0.36, 0.43, 0.09, 0.04, 0.39, 0.36, 0.0, 0.38, 0.62, 0.05, 0.09, 0.62, 0.58, 0.23, 0.82, 0.1, 0.49, 0.61, 0.75, 0.43, 0.21, 0.67, 0.63, 0.16, 0.44, 0.71, 0.23, 0.19, 0.6, 0.51, 0.17, 0.36, 0.47, 0.75, 0.19, 0.4, 0.69, 0.28, 0.0, 0.44, 0.64, 0.1, 0.04, 0.48, 0.46, 0.0, 0.38, 0.48, 0.32, 0.2, 0.32, 0.48, 0.42, 0.15, 0.28, 0.7, 0.46, 0.0, 0.43, 0.48, 0.08, 0.11, 0.64, 0.35, 0.0, 0.35, 0.56, 0.2, 0.03, 0.51, 0.32, 0.03, 0.14, 0.13, 0.13, 0.63, 0.76, 0.37, 0.22, 0.63, 0.71, 0.11, 0.66, 0.24, 0.28, 0.83, 0.29, 0.79, 0.71, 0.17, 0.43, 0.45, 0.54, 0.07, 0.2, 0.59, 0.49, 0.0, 0.41, 0.56, 0.14, 0.05, 0.56, 0.49, 0.0, 0.32, 0.57, 0.27, 0.13, 0.6, 0.82, 0.11, 0.31, 0.64, 0.06, 0.03, 0.51, 0.14, 0.02, 0.4, 0.46, 0.0, 0.25, 0.51, 0.1, 0.02, 0.57, 0.46, 0.0, 0.37, 0.33, 0.11, 0.06, 0.68, 0.39, 0.34, 0.36, 0.43, 0.81, 0.63, 0.13, 0.79, 0.75, 0.69, 0.95, 0.79, 0.65, 0.43, 0.37, 0.62, 0.63, 0.15, 0.32, 0.66, 0.46, 0.22, 0.37, 0.61, 0.09, 0.47, 0.72, 0.35, 0.0, 0.39, 0.66, 0.08, 0.13, 0.68, 0.41, 0.03, 0.45, 0.54, 0.34, 0.06, 0.46, 0.61, 0.11, 0.35, 0.7, 0.85, 0.38, 0.79, 0.69, 0.35, 0.02, 0.5, 0.12, 0.61, 0.56, 0.33, 0.43, 0.03, 0.35, 0.44, 0.32, 0.04, 0.52, 0.5, 0.27, 0.26, 0.39, 0.59, 0.18, 0.61, 0.48, 0.49, 0.36, 0.4, 0.54, 0.36, 0.45, 0.59, 0.51, 0.55, 0.57, 0.5, 0.54, 0.59, 0.54, 0.57, 0.52, 0.48, 0.47, 0.47, 0.41, 0.79, 0.9, 0.87, 0.5, 0.6, 0.81, 0.76, 0.91, 0.84, 0.92, 0.97, 0.97, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.93, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.95, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 0.96, 0.95, 0.86, 0.86, 0.84, 0.81, 0.82, 0.93, 0.84, 0.96, 0.84, 0.78, 0.84, 0.74, 0.66, 0.78, 0.73, 0.61, 0.79, 0.83, 0.84, 0.89, 0.81, 0.95, 0.86, 1.0, 0.76, 0.9, 0.89, 0.8, 0.9, 0.88, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0]
|
[47.08, 49.98, 45.1, 50.06, 47.52, 54.26, 58.49, 51.87, 58.52, 59.78, 64.46, 68.23, 76.3, 81.49, 85.58, 91.78, 93.13, 95.85, 97.27, 97.54, 98.27, 97.87, 97.58, 97.95, 98.36, 98.58, 98.68, 98.35, 98.47, 98.56, 97.99, 98.39, 98.23, 98.05, 97.9, 97.92, 97.46, 96.45, 96.25, 96.22, 94.82, 94.5, 89.02, 93.06, 94.76, 96.41, 97.14, 96.05, 90.84, 97.61, 98.15, 97.9, 98.5, 98.73, 98.51, 98.69, 98.75, 98.68, 98.75, 98.79, 98.68, 98.58, 98.76, 98.68, 98.43, 98.61, 98.7, 98.54, 98.56, 98.69, 98.65, 98.36, 97.84, 98.46, 98.11, 96.52, 95.46, 97.42, 97.69, 97.51, 98.52, 98.66, 98.56, 98.71, 98.31, 98.54, 98.72, 98.56, 98.04, 98.26, 98.58, 98.43, 97.42, 98.28, 98.13, 98.3, 98.5, 98.28, 98.43, 98.45, 98.23, 98.23, 98.47, 98.54, 98.4, 98.59, 98.03, 98.07, 97.86, 97.9, 96.63, 96.31, 96.68, 96.47, 96.29, 94.19, 94.48, 94.38, 92.56, 88.1, 78.09, 60.26, 54.15, 52.29, 49.59, 43.64, 42.38, 50.57]
|
[1.0, 0.98, 1.0, 0.97, 0.98, 0.95, 0.8, 0.93, 0.9, 0.75, 0.9, 0.88, 0.88, 0.95, 0.91, 0.92, 0.9, 0.48, 0.53, 0.33, 0.14, 0.69, 0.71, 0.4, 0.69, 0.16, 0.85, 0.27, 0.4, 0.0, 0.5, 0.61, 0.12, 0.19, 0.73, 0.54, 0.31, 0.6, 0.74, 0.91, 0.4, 0.86, 0.99, 0.93, 0.33, 0.94, 0.23, 0.56, 0.56, 0.74, 0.37, 0.0, 0.31, 0.7, 0.31, 0.0, 0.34, 0.44, 0.44, 0.21, 0.61, 0.37, 0.37, 0.54, 0.38, 0.15, 0.5, 0.62, 0.29, 0.0, 0.31, 0.4, 0.15, 0.03, 0.75, 0.76, 0.54, 0.88, 0.49, 0.98, 0.84, 0.39, 0.42, 0.4, 0.31, 0.04, 0.28, 0.1, 0.29, 0.06, 0.07, 0.25, 0.69, 0.33, 0.86, 0.76, 0.05, 0.28, 0.65, 0.64, 0.29, 0.66, 0.62, 0.95, 0.22, 0.76, 0.73, 0.02, 0.69, 0.75, 0.46, 0.79, 0.84, 0.72, 0.64, 0.81, 0.77, 0.76, 0.59, 0.8, 0.92, 0.96, 0.81, 0.94, 0.96, 0.88, 0.95, 0.91]
| null | null | null | null |
RACGAP1,CENPE,KIF4A,KIF23 ,KIF14 , KIF20A ,PLK1 ,KIF20B
| null | null | null | null |
Homodimer
| null | 78.712903
| 0.544032
| 90.240547
| 0.571797
| 2,087
|
O43663
|
P16104
|
22199232, E3Net
|
UbiNet, UbiBrowser, 31181401
|
PRC1
|
MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSFERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAPFCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGNLLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKERAKQERQLKNKKQTETEMLYGSAPRTPSKRRGLAPNTPGKARKLNTTTMSNATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPRTGRHGANKENLELNGSILSGGYPGSAPLQRNFSINSVASTYSEFAKDPSLSDSSTVGLQRELSKASKSDATSGILNSTNIQS
|
Homo sapiens
|
Nucleus, Cytoplasm, Cytoplasm, cytoskeleton, spindle pole, Midbody, Chromosome
|
Tissue enhanced (bone marrow, testis)
|
{'Ciliated cells': '1.9', 'Basal respiratory cells': '4.0', 'Club cells': '2.6', 'Ionocytes': '4.4', 'Mucus glandular cells': '2.0', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '0.6', 'Paneth cells': '4.4', 'Distal enterocytes': '1.4', 'Intestinal goblet cells': '8.6', 'Exocrine glandular cells': '-0.424', 'Basal prostatic cells': '0.4', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.512', 'Breast myoepithelial cells': '0.489', 'Glandular and luminal cells': '5.6', 'Secretory cells': '2.3', 'Basal keratinocytes': '13.6', 'Suprabasal keratinocytes': '9.0', 'Basal squamous epithelial cells': '8.2', 'Squamous epithelial cells': '24.9', 'Alveolar cells type 1': '-0.119', 'Alveolar cells type 2': '-0.065', 'Salivary duct cells': '2.2', 'Ductal cells': '0.452', 'Hepatocytes': '0.350', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.169', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.038', 'Sertoli cells': '-0.086', 'Granulosa cells': '6.8', 'Enteroendocrine cells': '4.0', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '-0.137', 'Excitatory neurons': '4.8', 'Inhibitory neurons': '5.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.5', 'Bipolar cells': '1.4', 'Horizontal cells': '0.6', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '1.6', 'Microglial cells': '1.8', 'Muller glia cells': '1.0', 'Schwann cells': '0.155', 'Spermatogonia': '0.356', 'Spermatocytes': '0.840', 'Early spermatids': '0.496', 'Late spermatids': '0.109', 'Oocytes': '73.5', 'Cytotrophoblasts': '23.6', 'Syncytiotrophoblasts': '9.7', 'Extravillous trophoblasts': '35.1', 'Endothelial cells': '2.1', 'Lymphatic endothelial cells': '3.2', 'Cardiomyocytes': '0.491', 'Skeletal myocytes': '0.090', 'Smooth muscle cells': '5.3', 'Adipocytes': '2.0', 'Melanocytes': '0.520', 'Fibroblasts': '4.4', 'Peritubular cells': '-0.165', 'Endometrial stromal cells': '2.7', 'Ovarian stromal cells': '2.7', 'Undifferentiated cells': '30.0', 'T-cells': '4.1', 'B-cells': '3.2', 'Plasma cells': '15.9', 'Nk-cells': '3.5', 'Granulocytes': '0.2', 'Monocytes': '3.9', 'Macrophages': '4.6', 'Hofbauer cells': '9.7', 'Kupffer cells': '3.6', 'Dendritic cells': '1.6', 'Langerhans cells': '0.161', 'Erythroid cells': '0.185', 'Adipocytes (Subcutaneous)': '-0.201', 'Adipocytes (Visceral)': '-0.143', 'Breast glandular cells (progenitors)': '0.409', 'Adipocytes (Breast)': '-0.476', 'Colon enterocytes': '0.263', 'Colon enteroendocrine cells': '0.079', 'Enteric glia cells': '-0.225', 'Mitotic cells (Colon)': '0.541', 'Mitotic cells (Heart)': '0.604', 'Podocytes': '-0.159', 'Ascending Loop of Henle cells': '0.380', 'Intercalated cells': '-0.085', 'Cholangiocyte': '0.398', 'NK-cells (Liver)': '-0.195', 'Respiratory ciliated cells': '0.056', 'Mitotic cells (Lung)': '0.656', 'NK-cells (Lung)': '0.131', 'B-cells (Lung)': '0.145', 'Alpha cells': '0.302', 'Beta cells': '0.192', 'Prostate glandular cells': '-0.169', 'Prostate basal glandular cells': '0.149', 'Urothelial cells': '0.144', 'Keratinocyte (other)': '0.346', 'Keratinocyte (granular)': '-0.148', 'Hair cortex cells': '0.062', 'Inner root sheath cells': '0.191', 'Outer root sheath cells': '0.198', 'Sebaceous gland cells': '-0.036', 'Eccrine sweat gland cells': '-0.063', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.827', 'Parietal cells': '0.011', 'Chief cells': '-0.010', 'Gastric mucous cells': '0.442', 'Gastric enteroendocrine cells': '0.080', 'Mitotic cells (Stomach)': '0.781', 'Parafollicular cells': '0.050', 'Thyroid glandular cells': '0.042', 'Mitotic cells (Thyroid)': '0.436', 'Adrenal cortex cells': '0.466', 'Adrenal medulla cells': '0.134', 'Mitotic cells (Adrenal gland)': '0.879', 'Minor salivary glandular cells': '0.283', 'Minor salivary gland ductal cells': '-0.271', 'Minor salivary gland basal cells': '0.742', 'Mitotic cells (Minor salivary gland)': '0.849', 'Adipocytes (Minor salivary gland)': '0.243', 'Somatotropes': '-0.356', 'Lactotropes': '-0.338', 'Gonadotropes': '-0.061', 'Corticotropes': '-0.240', 'Thyrotropes': '-0.112', 'Undifferentiated cells (Pituitary gland)': '0.421', 'Mitotic cells (Spleen)': '0.927', 'Platelets': '0.103', 'Erythrocytes': '0.359', 'Hematopoietic stem cells': '0.419', 'B-cells (Spleen)': '-0.133', 'NK-cells (Spleen)': '-0.200', 'Amygdala excitatory': '2.4', 'Cerebellar inhibitory': '3.3', 'Cge interneuron': '3.1', 'Deep-layer corticothalamic and 6b': '3.4', 'Deep-layer intratelencephalic': '2.7', 'Deep-layer near-projecting': '2.7', 'Eccentric medium spiny neuron': '2.1', 'Hippocampal ca1-3': '3.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '2.8', 'Lamp5-lhx6 and chandelier': '2.9', 'Lower rhombic lip': '4.3', 'Mammillary body': '2.9', 'Medium spiny neuron': '2.1', 'Mge interneuron': '3.2', 'Midbrain-derived inhibitory': '3.4', 'Miscellaneous': '3.2', 'Splatter': '4.2', 'Thalamic excitatory': '3.6', 'Upper rhombic lip': '6.7', 'Upper-layer intratelencephalic': '2.4', 'Astrocyte': '1.9', 'Bergmann glia': '0.9', 'Central nervous system macrophage': '1.0', 'Choroid plexus epithelial cell': '1.9', 'Committed oligodendrocyte precursor': '1.2', 'Ependymal cell': '1.4', 'Oligodendrocyte': '1.6', 'Oligodendrocyte precursor cell': '1.4', 'Endothelial cell': '0.5', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '2.9', 'Fibroblast': '1.0', 'Leukocyte': '2.1', 'Basophil': '19.3', 'Eosinophil': '2.9', 'Neutrophil': '0.4', 'Classical monocyte': '9.4', 'Non-classical monocyte': '2.0', 'Intermediate monocyte': '1.7', 'T-reg': '9.6', 'GdT-cell': '0.6', 'MAIT T-cell': '5.1', 'Memory CD4 T-cell': '1.3', 'Naive CD4 T-cell': '3.9', 'Memory CD8 T-cell': '1.3', 'Naive CD8 T-cell': '3.0', 'Memory B-cell': '1.1', 'Naive B-cell': '7.6', 'Plasmacytoid DC': '7.2', 'Myeloid DC': '20.8', 'NK-cell': '5.5', 'Total PBMC': '5.6', 'Vd2 gdTCR': '5.9', 'Memory CD4 T-cell Th1\\/Th17': '5.8', 'Memory CD4 T-cell Th17': '8.8', 'Memory CD4 T-cell Th2': '10.5', 'Non-Vd2 gdTCR': '6.8', 'Memory CD4 T-cell Th1': '7.1', 'Memory CD4 T-cell TFH': '7.0', 'Terminal effector memory CD4 T-cell': '3.2', 'Central memory CD8 T-cell': '6.7', 'Effector memory CD8 T-cell': '11.4', 'Terminal effector memory CD8 T-cell': '4.9', 'Non-switched memory B-cell': '5.4', 'Plasmablast': '30.3', 'Switched memory B-cell': '9.2', 'Exhausted memory B-cell': '12.2', 'Progenitor cell': '8.9', 'Memory T-reg': '18.9', 'Naive CD4 T-cell activated': '1.9', 'Naive CD8 T-cell activated': '2.2', 'Naive T-reg': '5.7'}
|
3NRX, 3NRY, 4L3I, 4L6Y, 5KMG, 7VBG
|
{'Adipose Tissue': 4.147858471760798, 'Adrenal Gland': 2.6710627906976745, 'Bladder': 3.1262857142857143, 'Blood': 13.149674854682454, 'Blood Vessel': 5.947328838951311, 'Brain': 4.31794242997729, 'Breast': 4.309821350762528, 'Cervix Uteri': 4.6506842105263155, 'Colon': 4.7497498074454425, 'Esophagus': 8.736843598615916, 'Fallopian Tube': 4.434555555555556, 'Heart': 1.5854587340301975, 'Kidney': 1.5213134831460673, 'Liver': 1.0593992477876106, 'Lung': 6.157918685121107, 'Muscle': 1.129561892901619, 'Nerve': 5.434959612277868, 'Ovary': 6.205122222222222, 'Pancreas': 1.7725213414634144, 'Pituitary': 2.0718671378091873, 'Prostate': 2.9573167346938773, 'Salivary Gland': 5.272641975308642, 'Skin': 25.474678828081817, 'Small Intestine': 6.994807486631016, 'Spleen': 6.059149377593362, 'Stomach': 4.9196, 'Testis': 37.2926648199446, 'Thyroid': 3.203790045941807, 'Uterus': 4.478767605633803, 'Vagina': 9.09873076923077}
|
H2AX
|
MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVGPKAPSGGKKATQASQEY
|
Homo sapiens
|
Nucleus, Chromosome
|
Low tissue specificity
|
{'Ciliated cells': '26.7', 'Basal respiratory cells': '11.6', 'Club cells': '20.7', 'Ionocytes': '9.2', 'Mucus glandular cells': '15.2', 'Serous glandular cells': '10.1', 'Gastric mucus-secreting cells': '64.3', 'Proximal enterocytes': '36.1', 'Paneth cells': '41.0', 'Distal enterocytes': '42.6', 'Intestinal goblet cells': '48.3', 'Exocrine glandular cells': '-0.624', 'Basal prostatic cells': '38.8', 'Prostatic glandular cells': '20.1', 'Breast glandular cells': '0.291', 'Breast myoepithelial cells': '0.174', 'Glandular and luminal cells': '44.3', 'Secretory cells': '43.5', 'Basal keratinocytes': '37.1', 'Suprabasal keratinocytes': '26.3', 'Basal squamous epithelial cells': '99.3', 'Squamous epithelial cells': '104.2', 'Alveolar cells type 1': '-0.118', 'Alveolar cells type 2': '-0.006', 'Salivary duct cells': '31.1', 'Ductal cells': '0.556', 'Hepatocytes': '0.127', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.097', 'Distal tubular cells': '15.4', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.181', 'Sertoli cells': '0.147', 'Granulosa cells': '68.4', 'Enteroendocrine cells': '34.7', 'Pancreatic endocrine cells': '15.3', 'Leydig cells': '-0.010', 'Excitatory neurons': '3.8', 'Inhibitory neurons': '4.8', 'Cone photoreceptor cells': '61.2', 'Rod photoreceptor cells': '48.5', 'Bipolar cells': '20.0', 'Horizontal cells': '5.7', 'Astrocytes': '5.3', 'Oligodendrocyte precursor cells': '7.5', 'Oligodendrocytes': '18.4', 'Microglial cells': '4.5', 'Muller glia cells': '48.0', 'Schwann cells': '-0.032', 'Spermatogonia': '-0.037', 'Spermatocytes': '0.142', 'Early spermatids': '-0.067', 'Late spermatids': '-0.025', 'Oocytes': '14.0', 'Cytotrophoblasts': '86.0', 'Syncytiotrophoblasts': '60.9', 'Extravillous trophoblasts': '104.2', 'Endothelial cells': '44.7', 'Lymphatic endothelial cells': '36.9', 'Cardiomyocytes': '0.290', 'Skeletal myocytes': '-0.137', 'Smooth muscle cells': '60.1', 'Adipocytes': '142.8', 'Melanocytes': '0.382', 'Fibroblasts': '54.8', 'Peritubular cells': '-0.073', 'Endometrial stromal cells': '36.1', 'Ovarian stromal cells': '42.7', 'Undifferentiated cells': '90.0', 'T-cells': '105.3', 'B-cells': '62.7', 'Plasma cells': '74.7', 'Nk-cells': '55.6', 'Granulocytes': '32.5', 'Monocytes': '34.7', 'Macrophages': '53.9', 'Hofbauer cells': '37.9', 'Kupffer cells': '11.7', 'Dendritic cells': '52.5', 'Langerhans cells': '0.100', 'Erythroid cells': '-0.043', 'Adipocytes (Subcutaneous)': '-0.019', 'Adipocytes (Visceral)': '-0.002', 'Breast glandular cells (progenitors)': '0.281', 'Adipocytes (Breast)': '-0.157', 'Colon enterocytes': '0.184', 'Colon enteroendocrine cells': '-0.017', 'Enteric glia cells': '-0.170', 'Mitotic cells (Colon)': '0.238', 'Mitotic cells (Heart)': '0.454', 'Podocytes': '-0.251', 'Ascending Loop of Henle cells': '0.364', 'Intercalated cells': '-0.234', 'Cholangiocyte': '0.367', 'NK-cells (Liver)': '-0.190', 'Respiratory ciliated cells': '-0.034', 'Mitotic cells (Lung)': '0.378', 'NK-cells (Lung)': '-0.077', 'B-cells (Lung)': '-0.052', 'Alpha cells': '0.356', 'Beta cells': '0.233', 'Prostate glandular cells': '0.112', 'Prostate basal glandular cells': '0.255', 'Urothelial cells': '0.333', 'Keratinocyte (other)': '0.166', 'Keratinocyte (granular)': '-0.135', 'Hair cortex cells': '0.214', 'Inner root sheath cells': '0.310', 'Outer root sheath cells': '0.273', 'Sebaceous gland cells': '0.018', 'Eccrine sweat gland cells': '-0.122', 'Adipocytes (Skin)': '-0.175', 'Mitotic cells (Skin)': '0.560', 'Parietal cells': '-0.387', 'Chief cells': '-0.307', 'Gastric mucous cells': '0.108', 'Gastric enteroendocrine cells': '-0.167', 'Mitotic cells (Stomach)': '0.597', 'Parafollicular cells': '0.075', 'Thyroid glandular cells': '0.095', 'Mitotic cells (Thyroid)': '0.111', 'Adrenal cortex cells': '0.480', 'Adrenal medulla cells': '-0.041', 'Mitotic cells (Adrenal gland)': '-0.034', 'Minor salivary glandular cells': '0.200', 'Minor salivary gland ductal cells': '-0.321', 'Minor salivary gland basal cells': '0.648', 'Mitotic cells (Minor salivary gland)': '0.759', 'Adipocytes (Minor salivary gland)': '0.187', 'Somatotropes': '-0.193', 'Lactotropes': '-0.212', 'Gonadotropes': '0.009', 'Corticotropes': '-0.142', 'Thyrotropes': '-0.041', 'Undifferentiated cells (Pituitary gland)': '0.321', 'Mitotic cells (Spleen)': '0.659', 'Platelets': '0.127', 'Erythrocytes': '0.198', 'Hematopoietic stem cells': '0.222', 'B-cells (Spleen)': '-0.052', 'NK-cells (Spleen)': '-0.156', 'Amygdala excitatory': '5.5', 'Cerebellar inhibitory': '11.5', 'Cge interneuron': '9.6', 'Deep-layer corticothalamic and 6b': '5.4', 'Deep-layer intratelencephalic': '4.9', 'Deep-layer near-projecting': '8.0', 'Eccentric medium spiny neuron': '7.3', 'Hippocampal ca1-3': '5.3', 'Hippocampal ca4': '5.6', 'Hippocampal dentate gyrus': '4.5', 'Lamp5-lhx6 and chandelier': '9.9', 'Lower rhombic lip': '10.6', 'Mammillary body': '6.3', 'Medium spiny neuron': '4.8', 'Mge interneuron': '8.4', 'Midbrain-derived inhibitory': '10.0', 'Miscellaneous': '6.2', 'Splatter': '8.8', 'Thalamic excitatory': '8.7', 'Upper rhombic lip': '11.2', 'Upper-layer intratelencephalic': '5.1', 'Astrocyte': '9.4', 'Bergmann glia': '12.2', 'Central nervous system macrophage': '5.3', 'Choroid plexus epithelial cell': '6.7', 'Committed oligodendrocyte precursor': '20.1', 'Ependymal cell': '31.4', 'Oligodendrocyte': '30.5', 'Oligodendrocyte precursor cell': '15.6', 'Endothelial cell': '7.7', 'Pericyte': '7.1', 'Vascular associated smooth muscle cell': '6.9', 'Fibroblast': '6.7', 'Leukocyte': '9.3', 'Basophil': '10.4', 'Eosinophil': '4.3', 'Neutrophil': '2.3', 'Classical monocyte': '6.2', 'Non-classical monocyte': '3.1', 'Intermediate monocyte': '4.5', 'T-reg': '6.8', 'GdT-cell': '1.7', 'MAIT T-cell': '4.9', 'Memory CD4 T-cell': '1.7', 'Naive CD4 T-cell': '14.5', 'Memory CD8 T-cell': '1.7', 'Naive CD8 T-cell': '21.4', 'Memory B-cell': '1.0', 'Naive B-cell': '7.7', 'Plasmacytoid DC': '4.0', 'Myeloid DC': '8.6', 'NK-cell': '27.7', 'Total PBMC': '5.4', 'Vd2 gdTCR': '11.4', 'Memory CD4 T-cell Th1\\/Th17': '14.7', 'Memory CD4 T-cell Th17': '19.9', 'Memory CD4 T-cell Th2': '25.7', 'Non-Vd2 gdTCR': '7.2', 'Memory CD4 T-cell Th1': '28.0', 'Memory CD4 T-cell TFH': '17.9', 'Terminal effector memory CD4 T-cell': '3.8', 'Central memory CD8 T-cell': '4.7', 'Effector memory CD8 T-cell': '6.7', 'Terminal effector memory CD8 T-cell': '5.9', 'Non-switched memory B-cell': '4.2', 'Plasmablast': '20.5', 'Switched memory B-cell': '2.8', 'Exhausted memory B-cell': '4.6', 'Progenitor cell': '7.3', 'Memory T-reg': '26.9', 'Naive CD4 T-cell activated': '22.9', 'Naive CD8 T-cell activated': '29.5', 'Naive T-reg': '9.1'}
|
1YDP, 2AZM, 2D31, 2DYP, 3SHV, 3SQD, 3SZM, 3U3Z, 6K1I, 6K1J, 6K1K, 6ZWK, 7YQK
|
{}
|
[53.31, 74.6, 84.9, 86.04, 86.7, 89.37, 90.52, 89.38, 90.34, 91.81, 90.92, 93.47, 92.96, 92.84, 93.07, 92.97, 93.93, 93.17, 93.0, 91.94, 93.2, 92.1, 90.25, 91.99, 91.73, 92.97, 90.53, 90.39, 91.87, 89.43, 86.6, 90.67, 89.69, 88.59, 90.26, 90.54, 92.47, 91.85, 92.77, 92.34, 93.32, 93.95, 94.05, 93.53, 95.54, 94.55, 94.53, 94.39, 95.31, 95.37, 95.64, 96.6, 96.11, 95.9, 95.97, 95.93, 94.59, 94.69, 95.43, 95.74, 94.61, 94.39, 95.1, 95.19, 94.64, 94.21, 95.36, 94.77, 93.77, 94.02, 95.25, 93.77, 92.64, 94.09, 95.0, 94.04, 92.23, 93.32, 93.85, 91.74, 90.84, 92.4, 91.18, 87.45, 87.28, 84.44, 75.8, 76.23, 71.15, 69.55, 65.13, 67.42, 64.22, 73.94, 89.65, 91.58, 91.16, 91.21, 91.78, 92.85, 92.23, 91.29, 92.24, 93.22, 92.95, 92.48, 94.26, 95.21, 94.55, 93.8, 94.87, 95.88, 94.33, 94.56, 94.94, 95.72, 94.88, 93.88, 95.25, 95.94, 95.08, 94.83, 96.14, 96.44, 95.23, 95.55, 96.8, 96.32, 94.91, 94.29, 95.61, 94.89, 93.82, 93.6, 94.71, 93.7, 92.74, 92.22, 90.7, 90.49, 88.75, 86.74, 84.72, 81.18, 83.58, 86.39, 90.41, 91.0, 91.24, 92.02, 92.25, 93.18, 94.33, 95.22, 95.57, 95.85, 97.15, 96.66, 96.17, 97.19, 97.58, 96.98, 96.97, 97.04, 97.74, 96.43, 95.92, 96.5, 96.93, 96.38, 96.12, 96.45, 96.78, 97.06, 96.35, 97.06, 97.19, 96.93, 97.0, 97.69, 97.48, 96.56, 95.98, 95.92, 96.09, 94.34, 93.13, 93.52, 92.18, 92.76, 93.33, 94.74, 92.19, 94.22, 93.29, 94.44, 95.67, 94.59, 93.36, 93.97, 93.5, 90.44, 90.29, 89.13, 88.25, 85.75, 89.2, 90.77, 91.89, 94.8, 94.91, 95.78, 96.09, 95.49, 96.33, 97.47, 97.02, 96.88, 97.79, 97.62, 97.25, 97.9, 97.68, 97.22, 97.05, 97.43, 96.89, 95.64, 95.35, 95.71, 96.05, 94.62, 95.59, 96.53, 96.68, 96.82, 97.17, 97.22, 97.57, 97.31, 96.91, 97.12, 96.66, 95.27, 96.1, 96.16, 96.05, 94.86, 94.43, 94.43, 94.28, 92.57, 94.1, 91.67, 92.41, 91.77, 92.9, 91.23, 90.3, 91.19, 90.29, 88.8, 90.63, 90.15, 89.89, 90.22, 91.46, 92.07, 91.55, 92.35, 94.79, 94.34, 95.32, 96.11, 97.13, 97.02, 97.07, 96.07, 97.36, 97.58, 96.62, 96.45, 95.99, 95.25, 95.31, 94.72, 94.53, 94.9, 94.29, 95.03, 95.85, 95.6, 96.28, 96.69, 96.19, 97.03, 96.67, 96.73, 96.97, 96.64, 96.61, 95.92, 95.3, 94.37, 95.09, 93.91, 91.81, 90.26, 89.31, 89.14, 90.12, 90.84, 90.42, 90.31, 92.92, 92.21, 92.38, 94.08, 92.37, 93.93, 93.04, 90.47, 92.87, 91.03, 92.21, 92.99, 93.01, 91.98, 94.87, 96.19, 95.96, 96.0, 96.83, 97.39, 96.35, 96.91, 96.07, 96.8, 97.1, 95.64, 94.7, 95.34, 94.09, 91.2, 92.93, 93.08, 89.88, 88.37, 90.57, 89.99, 90.56, 91.93, 92.32, 92.09, 92.24, 92.28, 93.34, 94.14, 91.71, 93.54, 94.18, 94.39, 93.75, 92.49, 93.12, 91.9, 91.22, 90.53, 89.33, 87.64, 86.75, 86.27, 83.9, 82.77, 77.04, 78.09, 79.28, 76.15, 72.54, 62.21, 56.53, 65.61, 70.9, 81.59, 83.1, 84.66, 84.94, 88.88, 86.59, 90.34, 90.26, 91.18, 91.7, 92.43, 92.96, 90.97, 92.58, 92.37, 93.47, 93.41, 92.58, 92.68, 93.67, 93.24, 91.99, 92.77, 93.18, 92.81, 90.42, 91.47, 91.63, 90.6, 90.44, 90.91, 90.36, 88.72, 84.62, 86.3, 83.0, 84.79, 85.91, 84.18, 85.74, 82.87, 84.09, 86.86, 89.82, 89.83, 91.4, 91.54, 89.42, 91.78, 92.36, 91.33, 91.83, 92.79, 92.36, 91.27, 90.83, 90.9, 91.71, 89.92, 89.0, 88.7, 89.21, 88.37, 88.2, 88.8, 88.01, 83.63, 85.67, 86.6, 85.99, 82.23, 84.63, 83.4, 80.37, 78.47, 81.09, 78.8, 78.13, 77.08, 75.24, 72.54, 58.17, 56.31, 49.52, 50.84, 46.56, 44.31, 52.78, 41.14, 43.14, 40.63, 39.64, 38.83, 46.21, 44.39, 50.09, 46.93, 51.65, 43.95, 42.7, 44.35, 43.45, 44.27, 43.15, 51.43, 44.92, 39.72, 44.96, 40.71, 43.1, 38.53, 43.03, 41.53, 43.48, 39.1, 41.22, 42.0, 40.8, 42.85, 50.43, 49.85, 41.5, 41.83, 37.27, 35.06, 44.53, 45.16, 46.43, 43.35, 42.9, 56.34, 50.32, 50.66, 43.77, 48.21, 54.42, 50.96, 39.73, 41.79, 42.52, 39.25, 45.93, 36.07, 35.26, 32.22, 34.46, 38.57, 36.64, 44.17, 41.96, 47.32, 42.52, 48.1, 45.04, 41.14, 43.92, 34.45, 37.48, 36.01, 31.14, 32.43, 32.62, 34.91, 31.99, 34.44, 33.73, 32.06, 32.08, 31.98, 32.7, 31.19, 30.76, 38.48, 33.09, 34.84, 33.5, 34.17, 40.17, 30.73, 32.47, 32.45, 30.58, 35.21, 32.34, 34.79, 33.46, 31.33, 34.13, 30.12, 31.1, 32.14, 35.58, 34.7, 37.56, 46.29, 40.25, 52.47, 44.59, 44.36, 45.32, 39.7, 35.96, 40.42, 37.26, 31.13, 32.62, 29.96, 34.06, 30.61, 33.76, 34.02, 34.76, 39.3, 35.91, 36.18, 35.97, 37.91, 40.12, 39.4, 37.6, 39.85, 39.02, 40.68, 39.38, 40.26, 40.13, 41.09, 42.89, 42.37, 43.04, 41.64, 39.92, 43.38, 41.37, 42.12, 44.72, 40.59]
|
[0.66, 0.73, 0.87, 0.66, 0.4, 0.37, 0.61, 0.43, 0.49, 0.59, 0.51, 0.65, 0.43, 0.61, 0.38, 0.57, 0.65, 0.47, 0.39, 0.52, 0.54, 0.32, 0.58, 0.56, 0.41, 0.1, 0.46, 0.87, 0.66, 0.68, 0.15, 0.55, 0.64, 0.59, 0.43, 0.11, 0.61, 0.59, 0.4, 0.32, 0.51, 0.53, 0.33, 0.57, 0.58, 0.59, 0.33, 0.59, 0.46, 0.56, 0.5, 0.44, 0.5, 0.49, 0.63, 0.56, 0.51, 0.43, 0.46, 0.4, 0.21, 0.45, 0.67, 0.55, 0.17, 0.49, 0.7, 0.23, 0.11, 0.4, 0.56, 0.09, 0.33, 0.67, 0.27, 0.04, 0.55, 0.52, 0.04, 0.06, 0.65, 0.29, 0.01, 0.73, 0.33, 0.9, 0.61, 0.39, 0.82, 0.49, 0.86, 0.67, 0.98, 0.41, 0.65, 0.45, 0.55, 0.38, 0.14, 0.09, 0.55, 0.31, 0.02, 0.44, 0.53, 0.21, 0.02, 0.54, 0.48, 0.04, 0.48, 0.56, 0.3, 0.24, 0.62, 0.48, 0.1, 0.3, 0.56, 0.32, 0.02, 0.57, 0.52, 0.08, 0.29, 0.49, 0.24, 0.03, 0.5, 0.52, 0.03, 0.02, 0.55, 0.25, 0.01, 0.72, 0.47, 0.88, 0.6, 0.3, 0.96, 0.17, 0.53, 0.55, 0.74, 0.47, 0.11, 0.02, 0.17, 0.52, 0.66, 0.43, 0.0, 0.43, 0.52, 0.01, 0.33, 0.66, 0.3, 0.0, 0.44, 0.49, 0.09, 0.46, 0.61, 0.35, 0.24, 0.56, 0.6, 0.13, 0.31, 0.72, 0.34, 0.0, 0.36, 0.49, 0.1, 0.09, 0.72, 0.39, 0.0, 0.32, 0.54, 0.07, 0.04, 0.57, 0.31, 0.12, 0.46, 0.31, 0.89, 0.25, 0.67, 0.51, 0.56, 0.24, 0.08, 0.43, 0.43, 0.0, 0.28, 0.72, 0.61, 0.78, 0.36, 0.7, 0.73, 0.09, 0.37, 0.05, 0.13, 0.63, 0.75, 0.26, 0.07, 0.47, 0.34, 0.0, 0.29, 0.59, 0.11, 0.11, 0.54, 0.56, 0.05, 0.45, 0.55, 0.43, 0.43, 0.49, 0.55, 0.19, 0.41, 0.62, 0.38, 0.0, 0.36, 0.43, 0.09, 0.04, 0.39, 0.36, 0.0, 0.38, 0.62, 0.05, 0.09, 0.62, 0.58, 0.23, 0.82, 0.1, 0.49, 0.61, 0.75, 0.43, 0.21, 0.67, 0.63, 0.16, 0.44, 0.71, 0.23, 0.19, 0.6, 0.51, 0.17, 0.36, 0.47, 0.75, 0.19, 0.4, 0.69, 0.28, 0.0, 0.44, 0.64, 0.1, 0.04, 0.48, 0.46, 0.0, 0.38, 0.48, 0.32, 0.2, 0.32, 0.48, 0.42, 0.15, 0.28, 0.7, 0.46, 0.0, 0.43, 0.48, 0.08, 0.11, 0.64, 0.35, 0.0, 0.35, 0.56, 0.2, 0.03, 0.51, 0.32, 0.03, 0.14, 0.13, 0.13, 0.63, 0.76, 0.37, 0.22, 0.63, 0.71, 0.11, 0.66, 0.24, 0.28, 0.83, 0.29, 0.79, 0.71, 0.17, 0.43, 0.45, 0.54, 0.07, 0.2, 0.59, 0.49, 0.0, 0.41, 0.56, 0.14, 0.05, 0.56, 0.49, 0.0, 0.32, 0.57, 0.27, 0.13, 0.6, 0.82, 0.11, 0.31, 0.64, 0.06, 0.03, 0.51, 0.14, 0.02, 0.4, 0.46, 0.0, 0.25, 0.51, 0.1, 0.02, 0.57, 0.46, 0.0, 0.37, 0.33, 0.11, 0.06, 0.68, 0.39, 0.34, 0.36, 0.43, 0.81, 0.63, 0.13, 0.79, 0.75, 0.69, 0.95, 0.79, 0.65, 0.43, 0.37, 0.62, 0.63, 0.15, 0.32, 0.66, 0.46, 0.22, 0.37, 0.61, 0.09, 0.47, 0.72, 0.35, 0.0, 0.39, 0.66, 0.08, 0.13, 0.68, 0.41, 0.03, 0.45, 0.54, 0.34, 0.06, 0.46, 0.61, 0.11, 0.35, 0.7, 0.85, 0.38, 0.79, 0.69, 0.35, 0.02, 0.5, 0.12, 0.61, 0.56, 0.33, 0.43, 0.03, 0.35, 0.44, 0.32, 0.04, 0.52, 0.5, 0.27, 0.26, 0.39, 0.59, 0.18, 0.61, 0.48, 0.49, 0.36, 0.4, 0.54, 0.36, 0.45, 0.59, 0.51, 0.55, 0.57, 0.5, 0.54, 0.59, 0.54, 0.57, 0.52, 0.48, 0.47, 0.47, 0.41, 0.79, 0.9, 0.87, 0.5, 0.6, 0.81, 0.76, 0.91, 0.84, 0.92, 0.97, 0.97, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.93, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.95, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 0.96, 0.95, 0.86, 0.86, 0.84, 0.81, 0.82, 0.93, 0.84, 0.96, 0.84, 0.78, 0.84, 0.74, 0.66, 0.78, 0.73, 0.61, 0.79, 0.83, 0.84, 0.89, 0.81, 0.95, 0.86, 1.0, 0.76, 0.9, 0.89, 0.8, 0.9, 0.88, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0]
|
[49.99, 60.69, 59.85, 55.26, 59.21, 63.92, 60.94, 59.42, 56.83, 56.81, 60.13, 66.08, 71.38, 76.77, 84.9, 91.45, 95.69, 96.97, 98.17, 97.25, 97.16, 97.81, 98.16, 98.5, 98.54, 98.36, 98.53, 98.65, 98.11, 98.52, 98.64, 98.47, 98.52, 98.55, 98.38, 97.64, 98.06, 97.95, 97.07, 97.57, 97.63, 97.28, 98.02, 97.83, 97.9, 97.27, 98.23, 98.61, 98.69, 98.73, 98.81, 98.73, 98.82, 98.81, 98.71, 98.78, 98.76, 98.59, 98.59, 98.77, 98.66, 98.44, 98.62, 98.77, 98.63, 98.71, 98.79, 98.78, 98.68, 98.56, 98.77, 98.59, 97.97, 97.79, 98.36, 98.37, 98.21, 98.76, 98.76, 98.7, 98.8, 98.66, 98.77, 98.78, 98.64, 98.55, 98.57, 98.57, 98.5, 97.97, 98.39, 98.19, 98.29, 98.48, 98.28, 98.44, 98.33, 98.26, 97.63, 98.17, 98.54, 98.58, 98.31, 98.6, 98.34, 98.31, 98.23, 98.13, 97.62, 97.26, 97.38, 97.31, 96.91, 94.91, 95.41, 95.82, 94.22, 93.32, 83.71, 75.02, 60.79, 46.69, 47.42, 43.6, 46.11, 52.53, 51.37, 48.06, 55.32, 52.07, 48.7, 50.58, 44.58, 51.79, 45.97, 51.31, 50.12, 50.59, 53.19, 50.64, 55.34, 52.36, 54.8]
|
[0.99, 0.92, 0.85, 0.8, 0.76, 0.95, 0.94, 0.82, 0.88, 0.82, 0.94, 0.94, 0.82, 0.94, 0.81, 0.71, 0.52, 0.39, 0.13, 0.54, 0.7, 0.38, 0.72, 0.16, 0.87, 0.28, 0.41, 0.0, 0.45, 0.6, 0.11, 0.18, 0.64, 0.57, 0.16, 0.5, 0.73, 0.44, 0.79, 0.72, 0.58, 0.95, 0.91, 0.18, 0.58, 0.66, 0.57, 0.44, 0.0, 0.33, 0.74, 0.37, 0.0, 0.38, 0.35, 0.38, 0.22, 0.66, 0.34, 0.37, 0.51, 0.38, 0.22, 0.53, 0.61, 0.26, 0.0, 0.34, 0.23, 0.1, 0.02, 0.69, 0.77, 0.48, 0.9, 0.53, 0.97, 0.81, 0.41, 0.44, 0.37, 0.27, 0.02, 0.27, 0.1, 0.14, 0.08, 0.05, 0.19, 0.67, 0.3, 0.84, 0.78, 0.06, 0.37, 0.85, 0.65, 0.23, 0.6, 0.95, 0.5, 0.94, 0.23, 0.77, 0.83, 0.03, 0.66, 0.77, 0.38, 0.82, 0.77, 0.7, 0.63, 0.66, 0.88, 0.76, 0.57, 0.91, 0.84, 0.95, 0.79, 0.75, 0.97, 0.78, 0.94, 0.89, 0.91, 0.94, 0.9, 0.88, 0.92, 0.85, 0.93, 0.95, 1.0, 0.95, 1.0, 1.0, 0.99, 0.98, 0.98, 0.99, 0.99]
| null | null | null | null |
RACGAP1,CENPE,KIF4A,KIF23 ,KIF14 , KIF20A ,PLK1 ,KIF20B
| null | null | null | null |
Homodimer
| null | 78.712903
| 0.544032
| 86.444126
| 0.59972
| 2,087
|
O43663
|
Q6FI13
|
22199232, E3Net
|
UbiNet, UbiBrowser, 31181401
|
PRC1
|
MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSFERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAPFCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGNLLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKERAKQERQLKNKKQTETEMLYGSAPRTPSKRRGLAPNTPGKARKLNTTTMSNATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPRTGRHGANKENLELNGSILSGGYPGSAPLQRNFSINSVASTYSEFAKDPSLSDSSTVGLQRELSKASKSDATSGILNSTNIQS
|
Homo sapiens
|
Nucleus, Cytoplasm, Cytoplasm, cytoskeleton, spindle pole, Midbody, Chromosome
|
Tissue enhanced (bone marrow, testis)
|
{'Ciliated cells': '1.9', 'Basal respiratory cells': '4.0', 'Club cells': '2.6', 'Ionocytes': '4.4', 'Mucus glandular cells': '2.0', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '0.6', 'Paneth cells': '4.4', 'Distal enterocytes': '1.4', 'Intestinal goblet cells': '8.6', 'Exocrine glandular cells': '-0.424', 'Basal prostatic cells': '0.4', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.512', 'Breast myoepithelial cells': '0.489', 'Glandular and luminal cells': '5.6', 'Secretory cells': '2.3', 'Basal keratinocytes': '13.6', 'Suprabasal keratinocytes': '9.0', 'Basal squamous epithelial cells': '8.2', 'Squamous epithelial cells': '24.9', 'Alveolar cells type 1': '-0.119', 'Alveolar cells type 2': '-0.065', 'Salivary duct cells': '2.2', 'Ductal cells': '0.452', 'Hepatocytes': '0.350', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.169', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.038', 'Sertoli cells': '-0.086', 'Granulosa cells': '6.8', 'Enteroendocrine cells': '4.0', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '-0.137', 'Excitatory neurons': '4.8', 'Inhibitory neurons': '5.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.5', 'Bipolar cells': '1.4', 'Horizontal cells': '0.6', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '1.6', 'Microglial cells': '1.8', 'Muller glia cells': '1.0', 'Schwann cells': '0.155', 'Spermatogonia': '0.356', 'Spermatocytes': '0.840', 'Early spermatids': '0.496', 'Late spermatids': '0.109', 'Oocytes': '73.5', 'Cytotrophoblasts': '23.6', 'Syncytiotrophoblasts': '9.7', 'Extravillous trophoblasts': '35.1', 'Endothelial cells': '2.1', 'Lymphatic endothelial cells': '3.2', 'Cardiomyocytes': '0.491', 'Skeletal myocytes': '0.090', 'Smooth muscle cells': '5.3', 'Adipocytes': '2.0', 'Melanocytes': '0.520', 'Fibroblasts': '4.4', 'Peritubular cells': '-0.165', 'Endometrial stromal cells': '2.7', 'Ovarian stromal cells': '2.7', 'Undifferentiated cells': '30.0', 'T-cells': '4.1', 'B-cells': '3.2', 'Plasma cells': '15.9', 'Nk-cells': '3.5', 'Granulocytes': '0.2', 'Monocytes': '3.9', 'Macrophages': '4.6', 'Hofbauer cells': '9.7', 'Kupffer cells': '3.6', 'Dendritic cells': '1.6', 'Langerhans cells': '0.161', 'Erythroid cells': '0.185', 'Adipocytes (Subcutaneous)': '-0.201', 'Adipocytes (Visceral)': '-0.143', 'Breast glandular cells (progenitors)': '0.409', 'Adipocytes (Breast)': '-0.476', 'Colon enterocytes': '0.263', 'Colon enteroendocrine cells': '0.079', 'Enteric glia cells': '-0.225', 'Mitotic cells (Colon)': '0.541', 'Mitotic cells (Heart)': '0.604', 'Podocytes': '-0.159', 'Ascending Loop of Henle cells': '0.380', 'Intercalated cells': '-0.085', 'Cholangiocyte': '0.398', 'NK-cells (Liver)': '-0.195', 'Respiratory ciliated cells': '0.056', 'Mitotic cells (Lung)': '0.656', 'NK-cells (Lung)': '0.131', 'B-cells (Lung)': '0.145', 'Alpha cells': '0.302', 'Beta cells': '0.192', 'Prostate glandular cells': '-0.169', 'Prostate basal glandular cells': '0.149', 'Urothelial cells': '0.144', 'Keratinocyte (other)': '0.346', 'Keratinocyte (granular)': '-0.148', 'Hair cortex cells': '0.062', 'Inner root sheath cells': '0.191', 'Outer root sheath cells': '0.198', 'Sebaceous gland cells': '-0.036', 'Eccrine sweat gland cells': '-0.063', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.827', 'Parietal cells': '0.011', 'Chief cells': '-0.010', 'Gastric mucous cells': '0.442', 'Gastric enteroendocrine cells': '0.080', 'Mitotic cells (Stomach)': '0.781', 'Parafollicular cells': '0.050', 'Thyroid glandular cells': '0.042', 'Mitotic cells (Thyroid)': '0.436', 'Adrenal cortex cells': '0.466', 'Adrenal medulla cells': '0.134', 'Mitotic cells (Adrenal gland)': '0.879', 'Minor salivary glandular cells': '0.283', 'Minor salivary gland ductal cells': '-0.271', 'Minor salivary gland basal cells': '0.742', 'Mitotic cells (Minor salivary gland)': '0.849', 'Adipocytes (Minor salivary gland)': '0.243', 'Somatotropes': '-0.356', 'Lactotropes': '-0.338', 'Gonadotropes': '-0.061', 'Corticotropes': '-0.240', 'Thyrotropes': '-0.112', 'Undifferentiated cells (Pituitary gland)': '0.421', 'Mitotic cells (Spleen)': '0.927', 'Platelets': '0.103', 'Erythrocytes': '0.359', 'Hematopoietic stem cells': '0.419', 'B-cells (Spleen)': '-0.133', 'NK-cells (Spleen)': '-0.200', 'Amygdala excitatory': '2.4', 'Cerebellar inhibitory': '3.3', 'Cge interneuron': '3.1', 'Deep-layer corticothalamic and 6b': '3.4', 'Deep-layer intratelencephalic': '2.7', 'Deep-layer near-projecting': '2.7', 'Eccentric medium spiny neuron': '2.1', 'Hippocampal ca1-3': '3.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '2.8', 'Lamp5-lhx6 and chandelier': '2.9', 'Lower rhombic lip': '4.3', 'Mammillary body': '2.9', 'Medium spiny neuron': '2.1', 'Mge interneuron': '3.2', 'Midbrain-derived inhibitory': '3.4', 'Miscellaneous': '3.2', 'Splatter': '4.2', 'Thalamic excitatory': '3.6', 'Upper rhombic lip': '6.7', 'Upper-layer intratelencephalic': '2.4', 'Astrocyte': '1.9', 'Bergmann glia': '0.9', 'Central nervous system macrophage': '1.0', 'Choroid plexus epithelial cell': '1.9', 'Committed oligodendrocyte precursor': '1.2', 'Ependymal cell': '1.4', 'Oligodendrocyte': '1.6', 'Oligodendrocyte precursor cell': '1.4', 'Endothelial cell': '0.5', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '2.9', 'Fibroblast': '1.0', 'Leukocyte': '2.1', 'Basophil': '19.3', 'Eosinophil': '2.9', 'Neutrophil': '0.4', 'Classical monocyte': '9.4', 'Non-classical monocyte': '2.0', 'Intermediate monocyte': '1.7', 'T-reg': '9.6', 'GdT-cell': '0.6', 'MAIT T-cell': '5.1', 'Memory CD4 T-cell': '1.3', 'Naive CD4 T-cell': '3.9', 'Memory CD8 T-cell': '1.3', 'Naive CD8 T-cell': '3.0', 'Memory B-cell': '1.1', 'Naive B-cell': '7.6', 'Plasmacytoid DC': '7.2', 'Myeloid DC': '20.8', 'NK-cell': '5.5', 'Total PBMC': '5.6', 'Vd2 gdTCR': '5.9', 'Memory CD4 T-cell Th1\\/Th17': '5.8', 'Memory CD4 T-cell Th17': '8.8', 'Memory CD4 T-cell Th2': '10.5', 'Non-Vd2 gdTCR': '6.8', 'Memory CD4 T-cell Th1': '7.1', 'Memory CD4 T-cell TFH': '7.0', 'Terminal effector memory CD4 T-cell': '3.2', 'Central memory CD8 T-cell': '6.7', 'Effector memory CD8 T-cell': '11.4', 'Terminal effector memory CD8 T-cell': '4.9', 'Non-switched memory B-cell': '5.4', 'Plasmablast': '30.3', 'Switched memory B-cell': '9.2', 'Exhausted memory B-cell': '12.2', 'Progenitor cell': '8.9', 'Memory T-reg': '18.9', 'Naive CD4 T-cell activated': '1.9', 'Naive CD8 T-cell activated': '2.2', 'Naive T-reg': '5.7'}
|
3NRX, 3NRY, 4L3I, 4L6Y, 5KMG, 7VBG
|
{'Adipose Tissue': 4.147858471760798, 'Adrenal Gland': 2.6710627906976745, 'Bladder': 3.1262857142857143, 'Blood': 13.149674854682454, 'Blood Vessel': 5.947328838951311, 'Brain': 4.31794242997729, 'Breast': 4.309821350762528, 'Cervix Uteri': 4.6506842105263155, 'Colon': 4.7497498074454425, 'Esophagus': 8.736843598615916, 'Fallopian Tube': 4.434555555555556, 'Heart': 1.5854587340301975, 'Kidney': 1.5213134831460673, 'Liver': 1.0593992477876106, 'Lung': 6.157918685121107, 'Muscle': 1.129561892901619, 'Nerve': 5.434959612277868, 'Ovary': 6.205122222222222, 'Pancreas': 1.7725213414634144, 'Pituitary': 2.0718671378091873, 'Prostate': 2.9573167346938773, 'Salivary Gland': 5.272641975308642, 'Skin': 25.474678828081817, 'Small Intestine': 6.994807486631016, 'Spleen': 6.059149377593362, 'Stomach': 4.9196, 'Testis': 37.2926648199446, 'Thyroid': 3.203790045941807, 'Uterus': 4.478767605633803, 'Vagina': 9.09873076923077}
|
H2AC18
|
MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
|
Homo sapiens
|
Nucleus, Chromosome
|
Tissue enhanced (bone marrow, choroid plexus)
|
{}
|
6SE6, 6SEE, 6SEF, 6SEG, 6Y5D, 7JZV
|
{}
|
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|
[0.66, 0.73, 0.87, 0.66, 0.4, 0.37, 0.61, 0.43, 0.49, 0.59, 0.51, 0.65, 0.43, 0.61, 0.38, 0.57, 0.65, 0.47, 0.39, 0.52, 0.54, 0.32, 0.58, 0.56, 0.41, 0.1, 0.46, 0.87, 0.66, 0.68, 0.15, 0.55, 0.64, 0.59, 0.43, 0.11, 0.61, 0.59, 0.4, 0.32, 0.51, 0.53, 0.33, 0.57, 0.58, 0.59, 0.33, 0.59, 0.46, 0.56, 0.5, 0.44, 0.5, 0.49, 0.63, 0.56, 0.51, 0.43, 0.46, 0.4, 0.21, 0.45, 0.67, 0.55, 0.17, 0.49, 0.7, 0.23, 0.11, 0.4, 0.56, 0.09, 0.33, 0.67, 0.27, 0.04, 0.55, 0.52, 0.04, 0.06, 0.65, 0.29, 0.01, 0.73, 0.33, 0.9, 0.61, 0.39, 0.82, 0.49, 0.86, 0.67, 0.98, 0.41, 0.65, 0.45, 0.55, 0.38, 0.14, 0.09, 0.55, 0.31, 0.02, 0.44, 0.53, 0.21, 0.02, 0.54, 0.48, 0.04, 0.48, 0.56, 0.3, 0.24, 0.62, 0.48, 0.1, 0.3, 0.56, 0.32, 0.02, 0.57, 0.52, 0.08, 0.29, 0.49, 0.24, 0.03, 0.5, 0.52, 0.03, 0.02, 0.55, 0.25, 0.01, 0.72, 0.47, 0.88, 0.6, 0.3, 0.96, 0.17, 0.53, 0.55, 0.74, 0.47, 0.11, 0.02, 0.17, 0.52, 0.66, 0.43, 0.0, 0.43, 0.52, 0.01, 0.33, 0.66, 0.3, 0.0, 0.44, 0.49, 0.09, 0.46, 0.61, 0.35, 0.24, 0.56, 0.6, 0.13, 0.31, 0.72, 0.34, 0.0, 0.36, 0.49, 0.1, 0.09, 0.72, 0.39, 0.0, 0.32, 0.54, 0.07, 0.04, 0.57, 0.31, 0.12, 0.46, 0.31, 0.89, 0.25, 0.67, 0.51, 0.56, 0.24, 0.08, 0.43, 0.43, 0.0, 0.28, 0.72, 0.61, 0.78, 0.36, 0.7, 0.73, 0.09, 0.37, 0.05, 0.13, 0.63, 0.75, 0.26, 0.07, 0.47, 0.34, 0.0, 0.29, 0.59, 0.11, 0.11, 0.54, 0.56, 0.05, 0.45, 0.55, 0.43, 0.43, 0.49, 0.55, 0.19, 0.41, 0.62, 0.38, 0.0, 0.36, 0.43, 0.09, 0.04, 0.39, 0.36, 0.0, 0.38, 0.62, 0.05, 0.09, 0.62, 0.58, 0.23, 0.82, 0.1, 0.49, 0.61, 0.75, 0.43, 0.21, 0.67, 0.63, 0.16, 0.44, 0.71, 0.23, 0.19, 0.6, 0.51, 0.17, 0.36, 0.47, 0.75, 0.19, 0.4, 0.69, 0.28, 0.0, 0.44, 0.64, 0.1, 0.04, 0.48, 0.46, 0.0, 0.38, 0.48, 0.32, 0.2, 0.32, 0.48, 0.42, 0.15, 0.28, 0.7, 0.46, 0.0, 0.43, 0.48, 0.08, 0.11, 0.64, 0.35, 0.0, 0.35, 0.56, 0.2, 0.03, 0.51, 0.32, 0.03, 0.14, 0.13, 0.13, 0.63, 0.76, 0.37, 0.22, 0.63, 0.71, 0.11, 0.66, 0.24, 0.28, 0.83, 0.29, 0.79, 0.71, 0.17, 0.43, 0.45, 0.54, 0.07, 0.2, 0.59, 0.49, 0.0, 0.41, 0.56, 0.14, 0.05, 0.56, 0.49, 0.0, 0.32, 0.57, 0.27, 0.13, 0.6, 0.82, 0.11, 0.31, 0.64, 0.06, 0.03, 0.51, 0.14, 0.02, 0.4, 0.46, 0.0, 0.25, 0.51, 0.1, 0.02, 0.57, 0.46, 0.0, 0.37, 0.33, 0.11, 0.06, 0.68, 0.39, 0.34, 0.36, 0.43, 0.81, 0.63, 0.13, 0.79, 0.75, 0.69, 0.95, 0.79, 0.65, 0.43, 0.37, 0.62, 0.63, 0.15, 0.32, 0.66, 0.46, 0.22, 0.37, 0.61, 0.09, 0.47, 0.72, 0.35, 0.0, 0.39, 0.66, 0.08, 0.13, 0.68, 0.41, 0.03, 0.45, 0.54, 0.34, 0.06, 0.46, 0.61, 0.11, 0.35, 0.7, 0.85, 0.38, 0.79, 0.69, 0.35, 0.02, 0.5, 0.12, 0.61, 0.56, 0.33, 0.43, 0.03, 0.35, 0.44, 0.32, 0.04, 0.52, 0.5, 0.27, 0.26, 0.39, 0.59, 0.18, 0.61, 0.48, 0.49, 0.36, 0.4, 0.54, 0.36, 0.45, 0.59, 0.51, 0.55, 0.57, 0.5, 0.54, 0.59, 0.54, 0.57, 0.52, 0.48, 0.47, 0.47, 0.41, 0.79, 0.9, 0.87, 0.5, 0.6, 0.81, 0.76, 0.91, 0.84, 0.92, 0.97, 0.97, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.93, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.95, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 0.96, 0.95, 0.86, 0.86, 0.84, 0.81, 0.82, 0.93, 0.84, 0.96, 0.84, 0.78, 0.84, 0.74, 0.66, 0.78, 0.73, 0.61, 0.79, 0.83, 0.84, 0.89, 0.81, 0.95, 0.86, 1.0, 0.76, 0.9, 0.89, 0.8, 0.9, 0.88, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0]
|
[54.4, 57.52, 56.65, 60.74, 57.0, 57.7, 56.8, 55.3, 62.47, 68.43, 74.85, 77.57, 82.47, 85.17, 89.55, 92.81, 95.63, 96.02, 97.9, 96.8, 96.56, 97.25, 97.69, 98.4, 98.31, 98.42, 98.33, 98.57, 97.95, 98.38, 98.36, 98.25, 98.07, 98.28, 97.88, 96.77, 97.57, 97.4, 95.85, 95.33, 96.1, 96.34, 97.39, 96.95, 97.24, 95.23, 97.66, 98.33, 98.45, 98.59, 98.7, 98.43, 98.73, 98.76, 98.6, 98.65, 98.71, 98.22, 98.3, 98.61, 98.4, 98.35, 98.65, 98.62, 98.55, 98.72, 98.8, 98.75, 98.55, 98.42, 98.75, 98.46, 97.57, 96.98, 98.1, 98.32, 97.3, 98.67, 98.7, 98.42, 98.68, 98.48, 98.69, 98.53, 98.48, 98.15, 98.28, 98.39, 98.12, 97.18, 98.06, 97.89, 98.08, 98.33, 97.86, 98.05, 97.93, 97.57, 95.61, 96.77, 97.07, 97.38, 97.69, 98.2, 98.03, 97.82, 96.63, 96.26, 95.77, 94.65, 95.15, 95.85, 94.27, 93.73, 95.24, 94.66, 93.63, 92.64, 85.8, 81.69, 75.37, 70.72, 66.32, 61.23, 60.41, 57.46, 60.87, 56.24, 60.45, 55.42]
|
[1.0, 0.84, 0.95, 0.93, 0.72, 0.97, 0.89, 0.78, 0.84, 0.89, 0.89, 0.94, 0.88, 0.93, 0.89, 0.71, 0.52, 0.4, 0.11, 0.56, 0.72, 0.4, 0.72, 0.16, 0.88, 0.28, 0.34, 0.0, 0.42, 0.58, 0.15, 0.19, 0.71, 0.55, 0.18, 0.55, 0.79, 0.43, 0.76, 0.75, 0.59, 0.99, 0.94, 0.18, 0.56, 0.69, 0.58, 0.43, 0.0, 0.35, 0.72, 0.43, 0.01, 0.35, 0.35, 0.43, 0.2, 0.67, 0.34, 0.37, 0.5, 0.33, 0.22, 0.5, 0.61, 0.27, 0.0, 0.33, 0.3, 0.13, 0.03, 0.68, 0.76, 0.45, 0.89, 0.62, 0.98, 0.8, 0.4, 0.5, 0.36, 0.29, 0.02, 0.27, 0.07, 0.2, 0.07, 0.07, 0.19, 0.66, 0.3, 0.84, 0.75, 0.05, 0.35, 0.86, 0.64, 0.22, 0.58, 0.98, 0.49, 0.9, 0.2, 0.76, 0.85, 0.02, 0.69, 0.75, 0.37, 0.8, 0.76, 0.75, 0.6, 0.68, 0.89, 0.75, 0.59, 0.93, 0.92, 0.95, 0.89, 0.83, 0.76, 0.85, 0.85, 0.88, 0.86, 0.93, 0.86, 0.98]
| null | null | null | null |
RACGAP1,CENPE,KIF4A,KIF23 ,KIF14 , KIF20A ,PLK1 ,KIF20B
| null | null | null | null |
Homodimer
| null | 78.712903
| 0.544032
| 91.001923
| 0.567615
| 2,087
|
O43663
|
Q96KK5
|
22199232, E3Net
|
UbiNet, UbiBrowser, 31181401
|
PRC1
|
MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSFERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAPFCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGNLLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKERAKQERQLKNKKQTETEMLYGSAPRTPSKRRGLAPNTPGKARKLNTTTMSNATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPRTGRHGANKENLELNGSILSGGYPGSAPLQRNFSINSVASTYSEFAKDPSLSDSSTVGLQRELSKASKSDATSGILNSTNIQS
|
Homo sapiens
|
Nucleus, Cytoplasm, Cytoplasm, cytoskeleton, spindle pole, Midbody, Chromosome
|
Tissue enhanced (bone marrow, testis)
|
{'Ciliated cells': '1.9', 'Basal respiratory cells': '4.0', 'Club cells': '2.6', 'Ionocytes': '4.4', 'Mucus glandular cells': '2.0', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '0.6', 'Paneth cells': '4.4', 'Distal enterocytes': '1.4', 'Intestinal goblet cells': '8.6', 'Exocrine glandular cells': '-0.424', 'Basal prostatic cells': '0.4', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.512', 'Breast myoepithelial cells': '0.489', 'Glandular and luminal cells': '5.6', 'Secretory cells': '2.3', 'Basal keratinocytes': '13.6', 'Suprabasal keratinocytes': '9.0', 'Basal squamous epithelial cells': '8.2', 'Squamous epithelial cells': '24.9', 'Alveolar cells type 1': '-0.119', 'Alveolar cells type 2': '-0.065', 'Salivary duct cells': '2.2', 'Ductal cells': '0.452', 'Hepatocytes': '0.350', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.169', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.038', 'Sertoli cells': '-0.086', 'Granulosa cells': '6.8', 'Enteroendocrine cells': '4.0', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '-0.137', 'Excitatory neurons': '4.8', 'Inhibitory neurons': '5.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.5', 'Bipolar cells': '1.4', 'Horizontal cells': '0.6', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '1.6', 'Microglial cells': '1.8', 'Muller glia cells': '1.0', 'Schwann cells': '0.155', 'Spermatogonia': '0.356', 'Spermatocytes': '0.840', 'Early spermatids': '0.496', 'Late spermatids': '0.109', 'Oocytes': '73.5', 'Cytotrophoblasts': '23.6', 'Syncytiotrophoblasts': '9.7', 'Extravillous trophoblasts': '35.1', 'Endothelial cells': '2.1', 'Lymphatic endothelial cells': '3.2', 'Cardiomyocytes': '0.491', 'Skeletal myocytes': '0.090', 'Smooth muscle cells': '5.3', 'Adipocytes': '2.0', 'Melanocytes': '0.520', 'Fibroblasts': '4.4', 'Peritubular cells': '-0.165', 'Endometrial stromal cells': '2.7', 'Ovarian stromal cells': '2.7', 'Undifferentiated cells': '30.0', 'T-cells': '4.1', 'B-cells': '3.2', 'Plasma cells': '15.9', 'Nk-cells': '3.5', 'Granulocytes': '0.2', 'Monocytes': '3.9', 'Macrophages': '4.6', 'Hofbauer cells': '9.7', 'Kupffer cells': '3.6', 'Dendritic cells': '1.6', 'Langerhans cells': '0.161', 'Erythroid cells': '0.185', 'Adipocytes (Subcutaneous)': '-0.201', 'Adipocytes (Visceral)': '-0.143', 'Breast glandular cells (progenitors)': '0.409', 'Adipocytes (Breast)': '-0.476', 'Colon enterocytes': '0.263', 'Colon enteroendocrine cells': '0.079', 'Enteric glia cells': '-0.225', 'Mitotic cells (Colon)': '0.541', 'Mitotic cells (Heart)': '0.604', 'Podocytes': '-0.159', 'Ascending Loop of Henle cells': '0.380', 'Intercalated cells': '-0.085', 'Cholangiocyte': '0.398', 'NK-cells (Liver)': '-0.195', 'Respiratory ciliated cells': '0.056', 'Mitotic cells (Lung)': '0.656', 'NK-cells (Lung)': '0.131', 'B-cells (Lung)': '0.145', 'Alpha cells': '0.302', 'Beta cells': '0.192', 'Prostate glandular cells': '-0.169', 'Prostate basal glandular cells': '0.149', 'Urothelial cells': '0.144', 'Keratinocyte (other)': '0.346', 'Keratinocyte (granular)': '-0.148', 'Hair cortex cells': '0.062', 'Inner root sheath cells': '0.191', 'Outer root sheath cells': '0.198', 'Sebaceous gland cells': '-0.036', 'Eccrine sweat gland cells': '-0.063', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.827', 'Parietal cells': '0.011', 'Chief cells': '-0.010', 'Gastric mucous cells': '0.442', 'Gastric enteroendocrine cells': '0.080', 'Mitotic cells (Stomach)': '0.781', 'Parafollicular cells': '0.050', 'Thyroid glandular cells': '0.042', 'Mitotic cells (Thyroid)': '0.436', 'Adrenal cortex cells': '0.466', 'Adrenal medulla cells': '0.134', 'Mitotic cells (Adrenal gland)': '0.879', 'Minor salivary glandular cells': '0.283', 'Minor salivary gland ductal cells': '-0.271', 'Minor salivary gland basal cells': '0.742', 'Mitotic cells (Minor salivary gland)': '0.849', 'Adipocytes (Minor salivary gland)': '0.243', 'Somatotropes': '-0.356', 'Lactotropes': '-0.338', 'Gonadotropes': '-0.061', 'Corticotropes': '-0.240', 'Thyrotropes': '-0.112', 'Undifferentiated cells (Pituitary gland)': '0.421', 'Mitotic cells (Spleen)': '0.927', 'Platelets': '0.103', 'Erythrocytes': '0.359', 'Hematopoietic stem cells': '0.419', 'B-cells (Spleen)': '-0.133', 'NK-cells (Spleen)': '-0.200', 'Amygdala excitatory': '2.4', 'Cerebellar inhibitory': '3.3', 'Cge interneuron': '3.1', 'Deep-layer corticothalamic and 6b': '3.4', 'Deep-layer intratelencephalic': '2.7', 'Deep-layer near-projecting': '2.7', 'Eccentric medium spiny neuron': '2.1', 'Hippocampal ca1-3': '3.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '2.8', 'Lamp5-lhx6 and chandelier': '2.9', 'Lower rhombic lip': '4.3', 'Mammillary body': '2.9', 'Medium spiny neuron': '2.1', 'Mge interneuron': '3.2', 'Midbrain-derived inhibitory': '3.4', 'Miscellaneous': '3.2', 'Splatter': '4.2', 'Thalamic excitatory': '3.6', 'Upper rhombic lip': '6.7', 'Upper-layer intratelencephalic': '2.4', 'Astrocyte': '1.9', 'Bergmann glia': '0.9', 'Central nervous system macrophage': '1.0', 'Choroid plexus epithelial cell': '1.9', 'Committed oligodendrocyte precursor': '1.2', 'Ependymal cell': '1.4', 'Oligodendrocyte': '1.6', 'Oligodendrocyte precursor cell': '1.4', 'Endothelial cell': '0.5', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '2.9', 'Fibroblast': '1.0', 'Leukocyte': '2.1', 'Basophil': '19.3', 'Eosinophil': '2.9', 'Neutrophil': '0.4', 'Classical monocyte': '9.4', 'Non-classical monocyte': '2.0', 'Intermediate monocyte': '1.7', 'T-reg': '9.6', 'GdT-cell': '0.6', 'MAIT T-cell': '5.1', 'Memory CD4 T-cell': '1.3', 'Naive CD4 T-cell': '3.9', 'Memory CD8 T-cell': '1.3', 'Naive CD8 T-cell': '3.0', 'Memory B-cell': '1.1', 'Naive B-cell': '7.6', 'Plasmacytoid DC': '7.2', 'Myeloid DC': '20.8', 'NK-cell': '5.5', 'Total PBMC': '5.6', 'Vd2 gdTCR': '5.9', 'Memory CD4 T-cell Th1\\/Th17': '5.8', 'Memory CD4 T-cell Th17': '8.8', 'Memory CD4 T-cell Th2': '10.5', 'Non-Vd2 gdTCR': '6.8', 'Memory CD4 T-cell Th1': '7.1', 'Memory CD4 T-cell TFH': '7.0', 'Terminal effector memory CD4 T-cell': '3.2', 'Central memory CD8 T-cell': '6.7', 'Effector memory CD8 T-cell': '11.4', 'Terminal effector memory CD8 T-cell': '4.9', 'Non-switched memory B-cell': '5.4', 'Plasmablast': '30.3', 'Switched memory B-cell': '9.2', 'Exhausted memory B-cell': '12.2', 'Progenitor cell': '8.9', 'Memory T-reg': '18.9', 'Naive CD4 T-cell activated': '1.9', 'Naive CD8 T-cell activated': '2.2', 'Naive T-reg': '5.7'}
|
3NRX, 3NRY, 4L3I, 4L6Y, 5KMG, 7VBG
|
{'Adipose Tissue': 4.147858471760798, 'Adrenal Gland': 2.6710627906976745, 'Bladder': 3.1262857142857143, 'Blood': 13.149674854682454, 'Blood Vessel': 5.947328838951311, 'Brain': 4.31794242997729, 'Breast': 4.309821350762528, 'Cervix Uteri': 4.6506842105263155, 'Colon': 4.7497498074454425, 'Esophagus': 8.736843598615916, 'Fallopian Tube': 4.434555555555556, 'Heart': 1.5854587340301975, 'Kidney': 1.5213134831460673, 'Liver': 1.0593992477876106, 'Lung': 6.157918685121107, 'Muscle': 1.129561892901619, 'Nerve': 5.434959612277868, 'Ovary': 6.205122222222222, 'Pancreas': 1.7725213414634144, 'Pituitary': 2.0718671378091873, 'Prostate': 2.9573167346938773, 'Salivary Gland': 5.272641975308642, 'Skin': 25.474678828081817, 'Small Intestine': 6.994807486631016, 'Spleen': 6.059149377593362, 'Stomach': 4.9196, 'Testis': 37.2926648199446, 'Thyroid': 3.203790045941807, 'Uterus': 4.478767605633803, 'Vagina': 9.09873076923077}
|
H2AC12
|
MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAK
|
Homo sapiens
|
Nucleus, Chromosome
|
Tissue enriched (bone)
|
{'Ciliated cells': '0.8', 'Basal respiratory cells': '0.4', 'Club cells': '1.4', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '1.1', 'Gastric mucus-secreting cells': '18.9', 'Proximal enterocytes': '1.8', 'Paneth cells': '0.6', 'Distal enterocytes': '3.6', 'Intestinal goblet cells': '2.3', 'Exocrine glandular cells': '-0.015', 'Basal prostatic cells': '0.3', 'Prostatic glandular cells': '1.6', 'Breast glandular cells': '0.318', 'Breast myoepithelial cells': '0.263', 'Glandular and luminal cells': '3.8', 'Secretory cells': '1.9', 'Basal keratinocytes': '3.9', 'Suprabasal keratinocytes': '1.1', 'Basal squamous epithelial cells': '0.9', 'Squamous epithelial cells': '2.9', 'Alveolar cells type 1': '-0.023', 'Alveolar cells type 2': '-0.356', 'Salivary duct cells': '1.0', 'Ductal cells': '0.035', 'Hepatocytes': '0.175', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.197', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.108', 'Sertoli cells': '-0.129', 'Granulosa cells': '1.7', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.271', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.2', 'Schwann cells': '0.018', 'Spermatogonia': '-0.161', 'Spermatocytes': '0.021', 'Early spermatids': '0.235', 'Late spermatids': '0.363', 'Oocytes': '2.2', 'Cytotrophoblasts': '1.1', 'Syncytiotrophoblasts': '1.0', 'Extravillous trophoblasts': '2.6', 'Endothelial cells': '1.1', 'Lymphatic endothelial cells': '0.2', 'Cardiomyocytes': '0.029', 'Skeletal myocytes': '-0.062', 'Smooth muscle cells': '1.1', 'Adipocytes': '1.0', 'Melanocytes': '0.123', 'Fibroblasts': '1.2', 'Peritubular cells': '-0.248', 'Endometrial stromal cells': '2.1', 'Ovarian stromal cells': '0.8', 'Undifferentiated cells': '2.0', 'T-cells': '4.8', 'B-cells': '4.5', 'Plasma cells': '28.2', 'Nk-cells': '2.9', 'Granulocytes': '0.5', 'Monocytes': '0.2', 'Macrophages': '2.8', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.7', 'Dendritic cells': '0.4', 'Langerhans cells': '0.103', 'Erythroid cells': '-0.037', 'Adipocytes (Subcutaneous)': '-0.248', 'Adipocytes (Visceral)': '-0.244', 'Breast glandular cells (progenitors)': '0.176', 'Adipocytes (Breast)': '-0.463', 'Colon enterocytes': '0.124', 'Colon enteroendocrine cells': '0.005', 'Enteric glia cells': '-0.104', 'Mitotic cells (Colon)': '0.230', 'Mitotic cells (Heart)': '0.146', 'Podocytes': '0.028', 'Ascending Loop of Henle cells': '-0.064', 'Intercalated cells': '-0.125', 'Cholangiocyte': '0.148', 'NK-cells (Liver)': '-0.161', 'Respiratory ciliated cells': '0.107', 'Mitotic cells (Lung)': '0.038', 'NK-cells (Lung)': '0.277', 'B-cells (Lung)': '0.255', 'Alpha cells': '0.010', 'Beta cells': '0.013', 'Prostate glandular cells': '0.078', 'Prostate basal glandular cells': '0.116', 'Urothelial cells': '0.168', 'Keratinocyte (other)': '0.078', 'Keratinocyte (granular)': '-0.403', 'Hair cortex cells': '0.094', 'Inner root sheath cells': '0.165', 'Outer root sheath cells': '0.325', 'Sebaceous gland cells': '-0.072', 'Eccrine sweat gland cells': '0.101', 'Adipocytes (Skin)': '-0.100', 'Mitotic cells (Skin)': '0.252', 'Parietal cells': '-0.048', 'Chief cells': '-0.044', 'Gastric mucous cells': '0.102', 'Gastric enteroendocrine cells': '0.084', 'Mitotic cells (Stomach)': '0.125', 'Parafollicular cells': '0.011', 'Thyroid glandular cells': '-0.037', 'Mitotic cells (Thyroid)': '0.137', 'Adrenal cortex cells': '0.064', 'Adrenal medulla cells': '-0.064', 'Mitotic cells (Adrenal gland)': '0.046', 'Minor salivary glandular cells': '0.095', 'Minor salivary gland ductal cells': '-0.013', 'Minor salivary gland basal cells': '-0.037', 'Mitotic cells (Minor salivary gland)': '-0.043', 'Adipocytes (Minor salivary gland)': '-0.008', 'Somatotropes': '-0.130', 'Lactotropes': '-0.062', 'Gonadotropes': '-0.032', 'Corticotropes': '-0.134', 'Thyrotropes': '-0.016', 'Undifferentiated cells (Pituitary gland)': '0.108', 'Mitotic cells (Spleen)': '0.255', 'Platelets': '-0.193', 'Erythrocytes': '0.122', 'Hematopoietic stem cells': '-0.119', 'B-cells (Spleen)': '-0.092', 'NK-cells (Spleen)': '-0.056', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.0', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.0', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '0.0', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '1.6', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.0', 'Oligodendrocyte': '0.0', 'Oligodendrocyte precursor cell': '0.0', 'Endothelial cell': '0.1', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.2', 'Fibroblast': '0.0', 'Leukocyte': '0.3', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.7', 'GdT-cell': '2.2', 'MAIT T-cell': '0.1', 'Memory CD4 T-cell': '4.1', 'Naive CD4 T-cell': '0.1', 'Memory CD8 T-cell': '3.8', 'Naive CD8 T-cell': '0.2', 'Memory B-cell': '3.3', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.8', 'Total PBMC': '0.2', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.5', 'Memory CD4 T-cell Th17': '0.9', 'Memory CD4 T-cell Th2': '0.9', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '1.0', 'Memory CD4 T-cell TFH': '0.6', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.4', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.6', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.8', 'Naive CD4 T-cell activated': '0.2', 'Naive CD8 T-cell activated': '0.2', 'Naive T-reg': '0.5'}
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8OL1
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{}
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[54.71, 59.19, 58.22, 62.9, 59.07, 58.75, 57.07, 55.92, 64.55, 68.57, 74.99, 77.63, 82.19, 84.81, 89.08, 92.84, 95.54, 96.26, 97.95, 96.85, 96.6, 97.27, 97.75, 98.42, 98.34, 98.45, 98.33, 98.55, 97.95, 98.4, 98.37, 98.28, 98.06, 98.27, 97.97, 96.81, 97.53, 97.35, 95.84, 95.27, 96.07, 96.35, 97.43, 97.1, 97.28, 95.31, 97.69, 98.33, 98.48, 98.61, 98.72, 98.59, 98.74, 98.78, 98.61, 98.65, 98.73, 98.2, 98.28, 98.57, 98.4, 98.27, 98.61, 98.58, 98.49, 98.66, 98.77, 98.71, 98.5, 98.35, 98.71, 98.42, 97.46, 97.09, 98.15, 98.34, 97.29, 98.66, 98.66, 98.35, 98.63, 98.42, 98.65, 98.45, 98.41, 98.05, 98.18, 98.3, 97.98, 96.93, 97.92, 97.75, 97.97, 98.23, 97.77, 98.03, 97.78, 97.32, 95.37, 96.63, 96.88, 97.18, 97.41, 98.09, 97.98, 97.71, 96.38, 95.83, 95.24, 93.76, 94.69, 95.22, 94.14, 93.52, 95.1, 94.52, 93.77, 92.25, 86.57, 83.22, 78.3, 75.18, 70.55, 63.05, 64.29, 56.94, 61.02, 58.34]
|
[1.0, 0.93, 0.93, 0.94, 0.74, 0.96, 0.89, 0.8, 0.83, 0.92, 0.9, 0.93, 0.87, 0.93, 0.85, 0.72, 0.59, 0.41, 0.13, 0.59, 0.74, 0.41, 0.72, 0.16, 0.87, 0.29, 0.37, 0.0, 0.44, 0.61, 0.13, 0.19, 0.72, 0.56, 0.17, 0.54, 0.79, 0.44, 0.74, 0.73, 0.59, 0.98, 0.93, 0.18, 0.58, 0.66, 0.56, 0.43, 0.0, 0.35, 0.72, 0.37, 0.0, 0.36, 0.36, 0.44, 0.19, 0.65, 0.32, 0.36, 0.5, 0.35, 0.21, 0.49, 0.63, 0.27, 0.0, 0.34, 0.31, 0.14, 0.03, 0.68, 0.75, 0.46, 0.88, 0.62, 0.99, 0.81, 0.41, 0.5, 0.37, 0.28, 0.01, 0.28, 0.08, 0.19, 0.07, 0.07, 0.19, 0.64, 0.29, 0.84, 0.75, 0.04, 0.36, 0.86, 0.65, 0.24, 0.58, 0.98, 0.51, 0.91, 0.2, 0.78, 0.85, 0.01, 0.68, 0.79, 0.37, 0.82, 0.77, 0.69, 0.61, 0.66, 0.88, 0.72, 0.55, 0.93, 0.91, 0.95, 0.89, 0.86, 0.74, 0.83, 0.85, 0.9, 0.9, 0.96]
| null | null | null | null |
RACGAP1,CENPE,KIF4A,KIF23 ,KIF14 , KIF20A ,PLK1 ,KIF20B
| null | null | null | null |
Homodimer
| null | 78.712903
| 0.544032
| 91.717109
| 0.563828
| 2,087
|
O43663
|
Q96QV6
|
22199232, E3Net
|
UbiNet, UbiBrowser, 31181401
|
PRC1
|
MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSFERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAPFCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGNLLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKERAKQERQLKNKKQTETEMLYGSAPRTPSKRRGLAPNTPGKARKLNTTTMSNATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPRTGRHGANKENLELNGSILSGGYPGSAPLQRNFSINSVASTYSEFAKDPSLSDSSTVGLQRELSKASKSDATSGILNSTNIQS
|
Homo sapiens
|
Nucleus, Cytoplasm, Cytoplasm, cytoskeleton, spindle pole, Midbody, Chromosome
|
Tissue enhanced (bone marrow, testis)
|
{'Ciliated cells': '1.9', 'Basal respiratory cells': '4.0', 'Club cells': '2.6', 'Ionocytes': '4.4', 'Mucus glandular cells': '2.0', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '0.6', 'Paneth cells': '4.4', 'Distal enterocytes': '1.4', 'Intestinal goblet cells': '8.6', 'Exocrine glandular cells': '-0.424', 'Basal prostatic cells': '0.4', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.512', 'Breast myoepithelial cells': '0.489', 'Glandular and luminal cells': '5.6', 'Secretory cells': '2.3', 'Basal keratinocytes': '13.6', 'Suprabasal keratinocytes': '9.0', 'Basal squamous epithelial cells': '8.2', 'Squamous epithelial cells': '24.9', 'Alveolar cells type 1': '-0.119', 'Alveolar cells type 2': '-0.065', 'Salivary duct cells': '2.2', 'Ductal cells': '0.452', 'Hepatocytes': '0.350', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.169', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.038', 'Sertoli cells': '-0.086', 'Granulosa cells': '6.8', 'Enteroendocrine cells': '4.0', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '-0.137', 'Excitatory neurons': '4.8', 'Inhibitory neurons': '5.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.5', 'Bipolar cells': '1.4', 'Horizontal cells': '0.6', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '1.6', 'Microglial cells': '1.8', 'Muller glia cells': '1.0', 'Schwann cells': '0.155', 'Spermatogonia': '0.356', 'Spermatocytes': '0.840', 'Early spermatids': '0.496', 'Late spermatids': '0.109', 'Oocytes': '73.5', 'Cytotrophoblasts': '23.6', 'Syncytiotrophoblasts': '9.7', 'Extravillous trophoblasts': '35.1', 'Endothelial cells': '2.1', 'Lymphatic endothelial cells': '3.2', 'Cardiomyocytes': '0.491', 'Skeletal myocytes': '0.090', 'Smooth muscle cells': '5.3', 'Adipocytes': '2.0', 'Melanocytes': '0.520', 'Fibroblasts': '4.4', 'Peritubular cells': '-0.165', 'Endometrial stromal cells': '2.7', 'Ovarian stromal cells': '2.7', 'Undifferentiated cells': '30.0', 'T-cells': '4.1', 'B-cells': '3.2', 'Plasma cells': '15.9', 'Nk-cells': '3.5', 'Granulocytes': '0.2', 'Monocytes': '3.9', 'Macrophages': '4.6', 'Hofbauer cells': '9.7', 'Kupffer cells': '3.6', 'Dendritic cells': '1.6', 'Langerhans cells': '0.161', 'Erythroid cells': '0.185', 'Adipocytes (Subcutaneous)': '-0.201', 'Adipocytes (Visceral)': '-0.143', 'Breast glandular cells (progenitors)': '0.409', 'Adipocytes (Breast)': '-0.476', 'Colon enterocytes': '0.263', 'Colon enteroendocrine cells': '0.079', 'Enteric glia cells': '-0.225', 'Mitotic cells (Colon)': '0.541', 'Mitotic cells (Heart)': '0.604', 'Podocytes': '-0.159', 'Ascending Loop of Henle cells': '0.380', 'Intercalated cells': '-0.085', 'Cholangiocyte': '0.398', 'NK-cells (Liver)': '-0.195', 'Respiratory ciliated cells': '0.056', 'Mitotic cells (Lung)': '0.656', 'NK-cells (Lung)': '0.131', 'B-cells (Lung)': '0.145', 'Alpha cells': '0.302', 'Beta cells': '0.192', 'Prostate glandular cells': '-0.169', 'Prostate basal glandular cells': '0.149', 'Urothelial cells': '0.144', 'Keratinocyte (other)': '0.346', 'Keratinocyte (granular)': '-0.148', 'Hair cortex cells': '0.062', 'Inner root sheath cells': '0.191', 'Outer root sheath cells': '0.198', 'Sebaceous gland cells': '-0.036', 'Eccrine sweat gland cells': '-0.063', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.827', 'Parietal cells': '0.011', 'Chief cells': '-0.010', 'Gastric mucous cells': '0.442', 'Gastric enteroendocrine cells': '0.080', 'Mitotic cells (Stomach)': '0.781', 'Parafollicular cells': '0.050', 'Thyroid glandular cells': '0.042', 'Mitotic cells (Thyroid)': '0.436', 'Adrenal cortex cells': '0.466', 'Adrenal medulla cells': '0.134', 'Mitotic cells (Adrenal gland)': '0.879', 'Minor salivary glandular cells': '0.283', 'Minor salivary gland ductal cells': '-0.271', 'Minor salivary gland basal cells': '0.742', 'Mitotic cells (Minor salivary gland)': '0.849', 'Adipocytes (Minor salivary gland)': '0.243', 'Somatotropes': '-0.356', 'Lactotropes': '-0.338', 'Gonadotropes': '-0.061', 'Corticotropes': '-0.240', 'Thyrotropes': '-0.112', 'Undifferentiated cells (Pituitary gland)': '0.421', 'Mitotic cells (Spleen)': '0.927', 'Platelets': '0.103', 'Erythrocytes': '0.359', 'Hematopoietic stem cells': '0.419', 'B-cells (Spleen)': '-0.133', 'NK-cells (Spleen)': '-0.200', 'Amygdala excitatory': '2.4', 'Cerebellar inhibitory': '3.3', 'Cge interneuron': '3.1', 'Deep-layer corticothalamic and 6b': '3.4', 'Deep-layer intratelencephalic': '2.7', 'Deep-layer near-projecting': '2.7', 'Eccentric medium spiny neuron': '2.1', 'Hippocampal ca1-3': '3.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '2.8', 'Lamp5-lhx6 and chandelier': '2.9', 'Lower rhombic lip': '4.3', 'Mammillary body': '2.9', 'Medium spiny neuron': '2.1', 'Mge interneuron': '3.2', 'Midbrain-derived inhibitory': '3.4', 'Miscellaneous': '3.2', 'Splatter': '4.2', 'Thalamic excitatory': '3.6', 'Upper rhombic lip': '6.7', 'Upper-layer intratelencephalic': '2.4', 'Astrocyte': '1.9', 'Bergmann glia': '0.9', 'Central nervous system macrophage': '1.0', 'Choroid plexus epithelial cell': '1.9', 'Committed oligodendrocyte precursor': '1.2', 'Ependymal cell': '1.4', 'Oligodendrocyte': '1.6', 'Oligodendrocyte precursor cell': '1.4', 'Endothelial cell': '0.5', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '2.9', 'Fibroblast': '1.0', 'Leukocyte': '2.1', 'Basophil': '19.3', 'Eosinophil': '2.9', 'Neutrophil': '0.4', 'Classical monocyte': '9.4', 'Non-classical monocyte': '2.0', 'Intermediate monocyte': '1.7', 'T-reg': '9.6', 'GdT-cell': '0.6', 'MAIT T-cell': '5.1', 'Memory CD4 T-cell': '1.3', 'Naive CD4 T-cell': '3.9', 'Memory CD8 T-cell': '1.3', 'Naive CD8 T-cell': '3.0', 'Memory B-cell': '1.1', 'Naive B-cell': '7.6', 'Plasmacytoid DC': '7.2', 'Myeloid DC': '20.8', 'NK-cell': '5.5', 'Total PBMC': '5.6', 'Vd2 gdTCR': '5.9', 'Memory CD4 T-cell Th1\\/Th17': '5.8', 'Memory CD4 T-cell Th17': '8.8', 'Memory CD4 T-cell Th2': '10.5', 'Non-Vd2 gdTCR': '6.8', 'Memory CD4 T-cell Th1': '7.1', 'Memory CD4 T-cell TFH': '7.0', 'Terminal effector memory CD4 T-cell': '3.2', 'Central memory CD8 T-cell': '6.7', 'Effector memory CD8 T-cell': '11.4', 'Terminal effector memory CD8 T-cell': '4.9', 'Non-switched memory B-cell': '5.4', 'Plasmablast': '30.3', 'Switched memory B-cell': '9.2', 'Exhausted memory B-cell': '12.2', 'Progenitor cell': '8.9', 'Memory T-reg': '18.9', 'Naive CD4 T-cell activated': '1.9', 'Naive CD8 T-cell activated': '2.2', 'Naive T-reg': '5.7'}
|
3NRX, 3NRY, 4L3I, 4L6Y, 5KMG, 7VBG
|
{'Adipose Tissue': 4.147858471760798, 'Adrenal Gland': 2.6710627906976745, 'Bladder': 3.1262857142857143, 'Blood': 13.149674854682454, 'Blood Vessel': 5.947328838951311, 'Brain': 4.31794242997729, 'Breast': 4.309821350762528, 'Cervix Uteri': 4.6506842105263155, 'Colon': 4.7497498074454425, 'Esophagus': 8.736843598615916, 'Fallopian Tube': 4.434555555555556, 'Heart': 1.5854587340301975, 'Kidney': 1.5213134831460673, 'Liver': 1.0593992477876106, 'Lung': 6.157918685121107, 'Muscle': 1.129561892901619, 'Nerve': 5.434959612277868, 'Ovary': 6.205122222222222, 'Pancreas': 1.7725213414634144, 'Pituitary': 2.0718671378091873, 'Prostate': 2.9573167346938773, 'Salivary Gland': 5.272641975308642, 'Skin': 25.474678828081817, 'Small Intestine': 6.994807486631016, 'Spleen': 6.059149377593362, 'Stomach': 4.9196, 'Testis': 37.2926648199446, 'Thyroid': 3.203790045941807, 'Uterus': 4.478767605633803, 'Vagina': 9.09873076923077}
|
H2AC1
|
MSGRGKQGGKARAKSKSRSSRAGLQFPVGRIHRLLRKGNYAERIGAGAPVYLAAVLEYLTAEILELAGNASRDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTESHHHKAQSK
|
Homo sapiens
|
Nucleus, Chromosome
|
Tissue enriched (testis)
|
{'Ciliated cells': '0.0', 'Basal respiratory cells': '0.0', 'Club cells': '0.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.0', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '0.049', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '-0.077', 'Breast myoepithelial cells': '-0.123', 'Glandular and luminal cells': '0.0', 'Secretory cells': '0.0', 'Basal keratinocytes': '0.0', 'Suprabasal keratinocytes': '0.0', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '0.075', 'Alveolar cells type 2': '-0.018', 'Salivary duct cells': '0.0', 'Ductal cells': '-0.011', 'Hepatocytes': '0.182', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.590', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.039', 'Sertoli cells': '-0.300', 'Granulosa cells': '0.3', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.351', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '-0.047', 'Spermatogonia': '-0.253', 'Spermatocytes': '0.046', 'Early spermatids': '0.322', 'Late spermatids': '0.330', 'Oocytes': '22.1', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '0.3', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '-0.085', 'Skeletal myocytes': '-0.003', 'Smooth muscle cells': '0.0', 'Adipocytes': '0.0', 'Melanocytes': '-0.019', 'Fibroblasts': '0.0', 'Peritubular cells': '-0.338', 'Endometrial stromal cells': '0.0', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '0.0', 'T-cells': '0.0', 'B-cells': '0.0', 'Plasma cells': '0.0', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.1', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.024', 'Erythroid cells': '0.091', 'Adipocytes (Subcutaneous)': '0.042', 'Adipocytes (Visceral)': '-0.048', 'Breast glandular cells (progenitors)': '-0.031', 'Adipocytes (Breast)': '0.105', 'Colon enterocytes': '0.077', 'Colon enteroendocrine cells': '0.007', 'Enteric glia cells': '-0.032', 'Mitotic cells (Colon)': '0.079', 'Mitotic cells (Heart)': '-0.041', 'Podocytes': '0.102', 'Ascending Loop of Henle cells': '-0.096', 'Intercalated cells': '0.012', 'Cholangiocyte': '0.077', 'NK-cells (Liver)': '0.103', 'Respiratory ciliated cells': '-0.017', 'Mitotic cells (Lung)': '-0.049', 'NK-cells (Lung)': '0.011', 'B-cells (Lung)': '-0.031', 'Alpha cells': '0.026', 'Beta cells': '0.037', 'Prostate glandular cells': '0.056', 'Prostate basal glandular cells': '-0.109', 'Urothelial cells': '0.057', 'Keratinocyte (other)': '-0.029', 'Keratinocyte (granular)': '0.068', 'Hair cortex cells': '-0.046', 'Inner root sheath cells': '0.033', 'Outer root sheath cells': '-0.014', 'Sebaceous gland cells': '-0.079', 'Eccrine sweat gland cells': '0.055', 'Adipocytes (Skin)': '0.055', 'Mitotic cells (Skin)': '0.040', 'Parietal cells': '0.001', 'Chief cells': '-0.032', 'Gastric mucous cells': '0.024', 'Gastric enteroendocrine cells': '0.011', 'Mitotic cells (Stomach)': '0.000', 'Parafollicular cells': '0.029', 'Thyroid glandular cells': '-0.016', 'Mitotic cells (Thyroid)': '0.018', 'Adrenal cortex cells': '0.002', 'Adrenal medulla cells': '-0.095', 'Mitotic cells (Adrenal gland)': '0.001', 'Minor salivary glandular cells': '0.097', 'Minor salivary gland ductal cells': '0.019', 'Minor salivary gland basal cells': '0.025', 'Mitotic cells (Minor salivary gland)': '0.029', 'Adipocytes (Minor salivary gland)': '-0.090', 'Somatotropes': '0.042', 'Lactotropes': '0.000', 'Gonadotropes': '-0.020', 'Corticotropes': '0.012', 'Thyrotropes': '-0.013', 'Undifferentiated cells (Pituitary gland)': '0.055', 'Mitotic cells (Spleen)': '0.005', 'Platelets': '-0.097', 'Erythrocytes': '-0.083', 'Hematopoietic stem cells': '-0.058', 'B-cells (Spleen)': '-0.067', 'NK-cells (Spleen)': '-0.112', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.0', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.0', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '0.0', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.0', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.0', 'Oligodendrocyte': '0.0', 'Oligodendrocyte precursor cell': '0.0', 'Endothelial cell': '0.0', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.0', 'Leukocyte': '0.0', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
|
5GSU, 5GT0
|
{}
|
[53.31, 74.6, 84.9, 86.04, 86.7, 89.37, 90.52, 89.38, 90.34, 91.81, 90.92, 93.47, 92.96, 92.84, 93.07, 92.97, 93.93, 93.17, 93.0, 91.94, 93.2, 92.1, 90.25, 91.99, 91.73, 92.97, 90.53, 90.39, 91.87, 89.43, 86.6, 90.67, 89.69, 88.59, 90.26, 90.54, 92.47, 91.85, 92.77, 92.34, 93.32, 93.95, 94.05, 93.53, 95.54, 94.55, 94.53, 94.39, 95.31, 95.37, 95.64, 96.6, 96.11, 95.9, 95.97, 95.93, 94.59, 94.69, 95.43, 95.74, 94.61, 94.39, 95.1, 95.19, 94.64, 94.21, 95.36, 94.77, 93.77, 94.02, 95.25, 93.77, 92.64, 94.09, 95.0, 94.04, 92.23, 93.32, 93.85, 91.74, 90.84, 92.4, 91.18, 87.45, 87.28, 84.44, 75.8, 76.23, 71.15, 69.55, 65.13, 67.42, 64.22, 73.94, 89.65, 91.58, 91.16, 91.21, 91.78, 92.85, 92.23, 91.29, 92.24, 93.22, 92.95, 92.48, 94.26, 95.21, 94.55, 93.8, 94.87, 95.88, 94.33, 94.56, 94.94, 95.72, 94.88, 93.88, 95.25, 95.94, 95.08, 94.83, 96.14, 96.44, 95.23, 95.55, 96.8, 96.32, 94.91, 94.29, 95.61, 94.89, 93.82, 93.6, 94.71, 93.7, 92.74, 92.22, 90.7, 90.49, 88.75, 86.74, 84.72, 81.18, 83.58, 86.39, 90.41, 91.0, 91.24, 92.02, 92.25, 93.18, 94.33, 95.22, 95.57, 95.85, 97.15, 96.66, 96.17, 97.19, 97.58, 96.98, 96.97, 97.04, 97.74, 96.43, 95.92, 96.5, 96.93, 96.38, 96.12, 96.45, 96.78, 97.06, 96.35, 97.06, 97.19, 96.93, 97.0, 97.69, 97.48, 96.56, 95.98, 95.92, 96.09, 94.34, 93.13, 93.52, 92.18, 92.76, 93.33, 94.74, 92.19, 94.22, 93.29, 94.44, 95.67, 94.59, 93.36, 93.97, 93.5, 90.44, 90.29, 89.13, 88.25, 85.75, 89.2, 90.77, 91.89, 94.8, 94.91, 95.78, 96.09, 95.49, 96.33, 97.47, 97.02, 96.88, 97.79, 97.62, 97.25, 97.9, 97.68, 97.22, 97.05, 97.43, 96.89, 95.64, 95.35, 95.71, 96.05, 94.62, 95.59, 96.53, 96.68, 96.82, 97.17, 97.22, 97.57, 97.31, 96.91, 97.12, 96.66, 95.27, 96.1, 96.16, 96.05, 94.86, 94.43, 94.43, 94.28, 92.57, 94.1, 91.67, 92.41, 91.77, 92.9, 91.23, 90.3, 91.19, 90.29, 88.8, 90.63, 90.15, 89.89, 90.22, 91.46, 92.07, 91.55, 92.35, 94.79, 94.34, 95.32, 96.11, 97.13, 97.02, 97.07, 96.07, 97.36, 97.58, 96.62, 96.45, 95.99, 95.25, 95.31, 94.72, 94.53, 94.9, 94.29, 95.03, 95.85, 95.6, 96.28, 96.69, 96.19, 97.03, 96.67, 96.73, 96.97, 96.64, 96.61, 95.92, 95.3, 94.37, 95.09, 93.91, 91.81, 90.26, 89.31, 89.14, 90.12, 90.84, 90.42, 90.31, 92.92, 92.21, 92.38, 94.08, 92.37, 93.93, 93.04, 90.47, 92.87, 91.03, 92.21, 92.99, 93.01, 91.98, 94.87, 96.19, 95.96, 96.0, 96.83, 97.39, 96.35, 96.91, 96.07, 96.8, 97.1, 95.64, 94.7, 95.34, 94.09, 91.2, 92.93, 93.08, 89.88, 88.37, 90.57, 89.99, 90.56, 91.93, 92.32, 92.09, 92.24, 92.28, 93.34, 94.14, 91.71, 93.54, 94.18, 94.39, 93.75, 92.49, 93.12, 91.9, 91.22, 90.53, 89.33, 87.64, 86.75, 86.27, 83.9, 82.77, 77.04, 78.09, 79.28, 76.15, 72.54, 62.21, 56.53, 65.61, 70.9, 81.59, 83.1, 84.66, 84.94, 88.88, 86.59, 90.34, 90.26, 91.18, 91.7, 92.43, 92.96, 90.97, 92.58, 92.37, 93.47, 93.41, 92.58, 92.68, 93.67, 93.24, 91.99, 92.77, 93.18, 92.81, 90.42, 91.47, 91.63, 90.6, 90.44, 90.91, 90.36, 88.72, 84.62, 86.3, 83.0, 84.79, 85.91, 84.18, 85.74, 82.87, 84.09, 86.86, 89.82, 89.83, 91.4, 91.54, 89.42, 91.78, 92.36, 91.33, 91.83, 92.79, 92.36, 91.27, 90.83, 90.9, 91.71, 89.92, 89.0, 88.7, 89.21, 88.37, 88.2, 88.8, 88.01, 83.63, 85.67, 86.6, 85.99, 82.23, 84.63, 83.4, 80.37, 78.47, 81.09, 78.8, 78.13, 77.08, 75.24, 72.54, 58.17, 56.31, 49.52, 50.84, 46.56, 44.31, 52.78, 41.14, 43.14, 40.63, 39.64, 38.83, 46.21, 44.39, 50.09, 46.93, 51.65, 43.95, 42.7, 44.35, 43.45, 44.27, 43.15, 51.43, 44.92, 39.72, 44.96, 40.71, 43.1, 38.53, 43.03, 41.53, 43.48, 39.1, 41.22, 42.0, 40.8, 42.85, 50.43, 49.85, 41.5, 41.83, 37.27, 35.06, 44.53, 45.16, 46.43, 43.35, 42.9, 56.34, 50.32, 50.66, 43.77, 48.21, 54.42, 50.96, 39.73, 41.79, 42.52, 39.25, 45.93, 36.07, 35.26, 32.22, 34.46, 38.57, 36.64, 44.17, 41.96, 47.32, 42.52, 48.1, 45.04, 41.14, 43.92, 34.45, 37.48, 36.01, 31.14, 32.43, 32.62, 34.91, 31.99, 34.44, 33.73, 32.06, 32.08, 31.98, 32.7, 31.19, 30.76, 38.48, 33.09, 34.84, 33.5, 34.17, 40.17, 30.73, 32.47, 32.45, 30.58, 35.21, 32.34, 34.79, 33.46, 31.33, 34.13, 30.12, 31.1, 32.14, 35.58, 34.7, 37.56, 46.29, 40.25, 52.47, 44.59, 44.36, 45.32, 39.7, 35.96, 40.42, 37.26, 31.13, 32.62, 29.96, 34.06, 30.61, 33.76, 34.02, 34.76, 39.3, 35.91, 36.18, 35.97, 37.91, 40.12, 39.4, 37.6, 39.85, 39.02, 40.68, 39.38, 40.26, 40.13, 41.09, 42.89, 42.37, 43.04, 41.64, 39.92, 43.38, 41.37, 42.12, 44.72, 40.59]
|
[0.66, 0.73, 0.87, 0.66, 0.4, 0.37, 0.61, 0.43, 0.49, 0.59, 0.51, 0.65, 0.43, 0.61, 0.38, 0.57, 0.65, 0.47, 0.39, 0.52, 0.54, 0.32, 0.58, 0.56, 0.41, 0.1, 0.46, 0.87, 0.66, 0.68, 0.15, 0.55, 0.64, 0.59, 0.43, 0.11, 0.61, 0.59, 0.4, 0.32, 0.51, 0.53, 0.33, 0.57, 0.58, 0.59, 0.33, 0.59, 0.46, 0.56, 0.5, 0.44, 0.5, 0.49, 0.63, 0.56, 0.51, 0.43, 0.46, 0.4, 0.21, 0.45, 0.67, 0.55, 0.17, 0.49, 0.7, 0.23, 0.11, 0.4, 0.56, 0.09, 0.33, 0.67, 0.27, 0.04, 0.55, 0.52, 0.04, 0.06, 0.65, 0.29, 0.01, 0.73, 0.33, 0.9, 0.61, 0.39, 0.82, 0.49, 0.86, 0.67, 0.98, 0.41, 0.65, 0.45, 0.55, 0.38, 0.14, 0.09, 0.55, 0.31, 0.02, 0.44, 0.53, 0.21, 0.02, 0.54, 0.48, 0.04, 0.48, 0.56, 0.3, 0.24, 0.62, 0.48, 0.1, 0.3, 0.56, 0.32, 0.02, 0.57, 0.52, 0.08, 0.29, 0.49, 0.24, 0.03, 0.5, 0.52, 0.03, 0.02, 0.55, 0.25, 0.01, 0.72, 0.47, 0.88, 0.6, 0.3, 0.96, 0.17, 0.53, 0.55, 0.74, 0.47, 0.11, 0.02, 0.17, 0.52, 0.66, 0.43, 0.0, 0.43, 0.52, 0.01, 0.33, 0.66, 0.3, 0.0, 0.44, 0.49, 0.09, 0.46, 0.61, 0.35, 0.24, 0.56, 0.6, 0.13, 0.31, 0.72, 0.34, 0.0, 0.36, 0.49, 0.1, 0.09, 0.72, 0.39, 0.0, 0.32, 0.54, 0.07, 0.04, 0.57, 0.31, 0.12, 0.46, 0.31, 0.89, 0.25, 0.67, 0.51, 0.56, 0.24, 0.08, 0.43, 0.43, 0.0, 0.28, 0.72, 0.61, 0.78, 0.36, 0.7, 0.73, 0.09, 0.37, 0.05, 0.13, 0.63, 0.75, 0.26, 0.07, 0.47, 0.34, 0.0, 0.29, 0.59, 0.11, 0.11, 0.54, 0.56, 0.05, 0.45, 0.55, 0.43, 0.43, 0.49, 0.55, 0.19, 0.41, 0.62, 0.38, 0.0, 0.36, 0.43, 0.09, 0.04, 0.39, 0.36, 0.0, 0.38, 0.62, 0.05, 0.09, 0.62, 0.58, 0.23, 0.82, 0.1, 0.49, 0.61, 0.75, 0.43, 0.21, 0.67, 0.63, 0.16, 0.44, 0.71, 0.23, 0.19, 0.6, 0.51, 0.17, 0.36, 0.47, 0.75, 0.19, 0.4, 0.69, 0.28, 0.0, 0.44, 0.64, 0.1, 0.04, 0.48, 0.46, 0.0, 0.38, 0.48, 0.32, 0.2, 0.32, 0.48, 0.42, 0.15, 0.28, 0.7, 0.46, 0.0, 0.43, 0.48, 0.08, 0.11, 0.64, 0.35, 0.0, 0.35, 0.56, 0.2, 0.03, 0.51, 0.32, 0.03, 0.14, 0.13, 0.13, 0.63, 0.76, 0.37, 0.22, 0.63, 0.71, 0.11, 0.66, 0.24, 0.28, 0.83, 0.29, 0.79, 0.71, 0.17, 0.43, 0.45, 0.54, 0.07, 0.2, 0.59, 0.49, 0.0, 0.41, 0.56, 0.14, 0.05, 0.56, 0.49, 0.0, 0.32, 0.57, 0.27, 0.13, 0.6, 0.82, 0.11, 0.31, 0.64, 0.06, 0.03, 0.51, 0.14, 0.02, 0.4, 0.46, 0.0, 0.25, 0.51, 0.1, 0.02, 0.57, 0.46, 0.0, 0.37, 0.33, 0.11, 0.06, 0.68, 0.39, 0.34, 0.36, 0.43, 0.81, 0.63, 0.13, 0.79, 0.75, 0.69, 0.95, 0.79, 0.65, 0.43, 0.37, 0.62, 0.63, 0.15, 0.32, 0.66, 0.46, 0.22, 0.37, 0.61, 0.09, 0.47, 0.72, 0.35, 0.0, 0.39, 0.66, 0.08, 0.13, 0.68, 0.41, 0.03, 0.45, 0.54, 0.34, 0.06, 0.46, 0.61, 0.11, 0.35, 0.7, 0.85, 0.38, 0.79, 0.69, 0.35, 0.02, 0.5, 0.12, 0.61, 0.56, 0.33, 0.43, 0.03, 0.35, 0.44, 0.32, 0.04, 0.52, 0.5, 0.27, 0.26, 0.39, 0.59, 0.18, 0.61, 0.48, 0.49, 0.36, 0.4, 0.54, 0.36, 0.45, 0.59, 0.51, 0.55, 0.57, 0.5, 0.54, 0.59, 0.54, 0.57, 0.52, 0.48, 0.47, 0.47, 0.41, 0.79, 0.9, 0.87, 0.5, 0.6, 0.81, 0.76, 0.91, 0.84, 0.92, 0.97, 0.97, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.93, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.95, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 0.96, 0.95, 0.86, 0.86, 0.84, 0.81, 0.82, 0.93, 0.84, 0.96, 0.84, 0.78, 0.84, 0.74, 0.66, 0.78, 0.73, 0.61, 0.79, 0.83, 0.84, 0.89, 0.81, 0.95, 0.86, 1.0, 0.76, 0.9, 0.89, 0.8, 0.9, 0.88, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0]
|
[52.5, 56.49, 55.87, 60.37, 57.17, 57.61, 55.22, 53.74, 61.3, 67.16, 73.24, 75.79, 80.77, 83.96, 89.37, 92.4, 95.55, 95.97, 97.86, 96.82, 96.43, 97.31, 97.69, 98.37, 98.29, 98.41, 98.3, 98.56, 97.93, 98.36, 98.34, 98.32, 98.1, 98.29, 98.0, 97.0, 97.63, 97.41, 95.74, 95.44, 96.5, 96.37, 97.62, 97.5, 97.41, 95.33, 97.75, 98.35, 98.47, 98.6, 98.73, 98.58, 98.74, 98.77, 98.63, 98.66, 98.71, 98.21, 98.31, 98.57, 98.39, 98.29, 98.61, 98.57, 98.5, 98.68, 98.75, 98.69, 98.48, 98.36, 98.59, 98.34, 97.31, 96.81, 97.9, 98.08, 96.82, 98.61, 98.63, 98.31, 98.59, 98.4, 98.63, 98.44, 98.39, 98.03, 98.23, 98.31, 97.98, 97.03, 98.0, 97.73, 98.01, 98.26, 97.75, 97.97, 97.83, 97.48, 95.0, 95.3, 96.99, 97.35, 97.46, 98.09, 97.95, 97.68, 96.5, 96.07, 95.39, 94.09, 94.98, 95.87, 94.16, 93.52, 95.15, 94.81, 93.65, 92.37, 85.77, 81.73, 75.03, 70.57, 64.75, 59.01, 57.22, 54.16, 54.73, 61.06, 54.02, 54.74, 60.28]
|
[1.0, 0.91, 0.97, 0.95, 0.76, 0.97, 0.9, 0.79, 0.84, 0.9, 0.88, 0.92, 0.88, 0.91, 0.85, 0.73, 0.52, 0.4, 0.14, 0.57, 0.69, 0.42, 0.75, 0.16, 0.88, 0.29, 0.38, 0.0, 0.43, 0.58, 0.13, 0.18, 0.71, 0.55, 0.16, 0.53, 0.79, 0.43, 0.77, 0.72, 0.54, 0.97, 0.94, 0.17, 0.58, 0.65, 0.55, 0.42, 0.0, 0.36, 0.71, 0.37, 0.0, 0.37, 0.36, 0.41, 0.18, 0.65, 0.34, 0.36, 0.53, 0.4, 0.2, 0.5, 0.62, 0.27, 0.0, 0.25, 0.41, 0.13, 0.03, 0.78, 0.76, 0.44, 0.88, 0.6, 0.99, 0.79, 0.4, 0.5, 0.3, 0.29, 0.02, 0.28, 0.08, 0.2, 0.07, 0.06, 0.2, 0.66, 0.29, 0.82, 0.77, 0.05, 0.35, 0.86, 0.64, 0.24, 0.61, 0.95, 0.49, 0.89, 0.2, 0.76, 0.82, 0.01, 0.64, 0.76, 0.36, 0.79, 0.79, 0.64, 0.63, 0.67, 0.9, 0.72, 0.53, 0.92, 0.92, 0.94, 0.89, 0.83, 0.73, 0.77, 0.84, 0.84, 0.89, 0.85, 0.89, 0.92, 0.96]
| null | null | null | null |
RACGAP1,CENPE,KIF4A,KIF23 ,KIF14 , KIF20A ,PLK1 ,KIF20B
| null | null | null | null |
Homodimer
| null | 78.712903
| 0.544032
| 90.443664
| 0.567023
| 2,087
|
O43663
|
Q99496
|
22199232, E3Net
|
UbiNet, UbiBrowser, 31181401
|
PRC1
|
MRRSEVLAEESIVCLQKALNHLREIWELIGIPEDQRLQRTEVVKKHIKELLDMMIAEEESLKERLIKSISVCQKELNTLCSELHVEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEILCMPHYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSFERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAPFCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGNLLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKERAKQERQLKNKKQTETEMLYGSAPRTPSKRRGLAPNTPGKARKLNTTTMSNATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPRTGRHGANKENLELNGSILSGGYPGSAPLQRNFSINSVASTYSEFAKDPSLSDSSTVGLQRELSKASKSDATSGILNSTNIQS
|
Homo sapiens
|
Nucleus, Cytoplasm, Cytoplasm, cytoskeleton, spindle pole, Midbody, Chromosome
|
Tissue enhanced (bone marrow, testis)
|
{'Ciliated cells': '1.9', 'Basal respiratory cells': '4.0', 'Club cells': '2.6', 'Ionocytes': '4.4', 'Mucus glandular cells': '2.0', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '0.6', 'Paneth cells': '4.4', 'Distal enterocytes': '1.4', 'Intestinal goblet cells': '8.6', 'Exocrine glandular cells': '-0.424', 'Basal prostatic cells': '0.4', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.512', 'Breast myoepithelial cells': '0.489', 'Glandular and luminal cells': '5.6', 'Secretory cells': '2.3', 'Basal keratinocytes': '13.6', 'Suprabasal keratinocytes': '9.0', 'Basal squamous epithelial cells': '8.2', 'Squamous epithelial cells': '24.9', 'Alveolar cells type 1': '-0.119', 'Alveolar cells type 2': '-0.065', 'Salivary duct cells': '2.2', 'Ductal cells': '0.452', 'Hepatocytes': '0.350', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.169', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.038', 'Sertoli cells': '-0.086', 'Granulosa cells': '6.8', 'Enteroendocrine cells': '4.0', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '-0.137', 'Excitatory neurons': '4.8', 'Inhibitory neurons': '5.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.5', 'Bipolar cells': '1.4', 'Horizontal cells': '0.6', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '1.6', 'Microglial cells': '1.8', 'Muller glia cells': '1.0', 'Schwann cells': '0.155', 'Spermatogonia': '0.356', 'Spermatocytes': '0.840', 'Early spermatids': '0.496', 'Late spermatids': '0.109', 'Oocytes': '73.5', 'Cytotrophoblasts': '23.6', 'Syncytiotrophoblasts': '9.7', 'Extravillous trophoblasts': '35.1', 'Endothelial cells': '2.1', 'Lymphatic endothelial cells': '3.2', 'Cardiomyocytes': '0.491', 'Skeletal myocytes': '0.090', 'Smooth muscle cells': '5.3', 'Adipocytes': '2.0', 'Melanocytes': '0.520', 'Fibroblasts': '4.4', 'Peritubular cells': '-0.165', 'Endometrial stromal cells': '2.7', 'Ovarian stromal cells': '2.7', 'Undifferentiated cells': '30.0', 'T-cells': '4.1', 'B-cells': '3.2', 'Plasma cells': '15.9', 'Nk-cells': '3.5', 'Granulocytes': '0.2', 'Monocytes': '3.9', 'Macrophages': '4.6', 'Hofbauer cells': '9.7', 'Kupffer cells': '3.6', 'Dendritic cells': '1.6', 'Langerhans cells': '0.161', 'Erythroid cells': '0.185', 'Adipocytes (Subcutaneous)': '-0.201', 'Adipocytes (Visceral)': '-0.143', 'Breast glandular cells (progenitors)': '0.409', 'Adipocytes (Breast)': '-0.476', 'Colon enterocytes': '0.263', 'Colon enteroendocrine cells': '0.079', 'Enteric glia cells': '-0.225', 'Mitotic cells (Colon)': '0.541', 'Mitotic cells (Heart)': '0.604', 'Podocytes': '-0.159', 'Ascending Loop of Henle cells': '0.380', 'Intercalated cells': '-0.085', 'Cholangiocyte': '0.398', 'NK-cells (Liver)': '-0.195', 'Respiratory ciliated cells': '0.056', 'Mitotic cells (Lung)': '0.656', 'NK-cells (Lung)': '0.131', 'B-cells (Lung)': '0.145', 'Alpha cells': '0.302', 'Beta cells': '0.192', 'Prostate glandular cells': '-0.169', 'Prostate basal glandular cells': '0.149', 'Urothelial cells': '0.144', 'Keratinocyte (other)': '0.346', 'Keratinocyte (granular)': '-0.148', 'Hair cortex cells': '0.062', 'Inner root sheath cells': '0.191', 'Outer root sheath cells': '0.198', 'Sebaceous gland cells': '-0.036', 'Eccrine sweat gland cells': '-0.063', 'Adipocytes (Skin)': '-0.244', 'Mitotic cells (Skin)': '0.827', 'Parietal cells': '0.011', 'Chief cells': '-0.010', 'Gastric mucous cells': '0.442', 'Gastric enteroendocrine cells': '0.080', 'Mitotic cells (Stomach)': '0.781', 'Parafollicular cells': '0.050', 'Thyroid glandular cells': '0.042', 'Mitotic cells (Thyroid)': '0.436', 'Adrenal cortex cells': '0.466', 'Adrenal medulla cells': '0.134', 'Mitotic cells (Adrenal gland)': '0.879', 'Minor salivary glandular cells': '0.283', 'Minor salivary gland ductal cells': '-0.271', 'Minor salivary gland basal cells': '0.742', 'Mitotic cells (Minor salivary gland)': '0.849', 'Adipocytes (Minor salivary gland)': '0.243', 'Somatotropes': '-0.356', 'Lactotropes': '-0.338', 'Gonadotropes': '-0.061', 'Corticotropes': '-0.240', 'Thyrotropes': '-0.112', 'Undifferentiated cells (Pituitary gland)': '0.421', 'Mitotic cells (Spleen)': '0.927', 'Platelets': '0.103', 'Erythrocytes': '0.359', 'Hematopoietic stem cells': '0.419', 'B-cells (Spleen)': '-0.133', 'NK-cells (Spleen)': '-0.200', 'Amygdala excitatory': '2.4', 'Cerebellar inhibitory': '3.3', 'Cge interneuron': '3.1', 'Deep-layer corticothalamic and 6b': '3.4', 'Deep-layer intratelencephalic': '2.7', 'Deep-layer near-projecting': '2.7', 'Eccentric medium spiny neuron': '2.1', 'Hippocampal ca1-3': '3.9', 'Hippocampal ca4': '1.2', 'Hippocampal dentate gyrus': '2.8', 'Lamp5-lhx6 and chandelier': '2.9', 'Lower rhombic lip': '4.3', 'Mammillary body': '2.9', 'Medium spiny neuron': '2.1', 'Mge interneuron': '3.2', 'Midbrain-derived inhibitory': '3.4', 'Miscellaneous': '3.2', 'Splatter': '4.2', 'Thalamic excitatory': '3.6', 'Upper rhombic lip': '6.7', 'Upper-layer intratelencephalic': '2.4', 'Astrocyte': '1.9', 'Bergmann glia': '0.9', 'Central nervous system macrophage': '1.0', 'Choroid plexus epithelial cell': '1.9', 'Committed oligodendrocyte precursor': '1.2', 'Ependymal cell': '1.4', 'Oligodendrocyte': '1.6', 'Oligodendrocyte precursor cell': '1.4', 'Endothelial cell': '0.5', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '2.9', 'Fibroblast': '1.0', 'Leukocyte': '2.1', 'Basophil': '19.3', 'Eosinophil': '2.9', 'Neutrophil': '0.4', 'Classical monocyte': '9.4', 'Non-classical monocyte': '2.0', 'Intermediate monocyte': '1.7', 'T-reg': '9.6', 'GdT-cell': '0.6', 'MAIT T-cell': '5.1', 'Memory CD4 T-cell': '1.3', 'Naive CD4 T-cell': '3.9', 'Memory CD8 T-cell': '1.3', 'Naive CD8 T-cell': '3.0', 'Memory B-cell': '1.1', 'Naive B-cell': '7.6', 'Plasmacytoid DC': '7.2', 'Myeloid DC': '20.8', 'NK-cell': '5.5', 'Total PBMC': '5.6', 'Vd2 gdTCR': '5.9', 'Memory CD4 T-cell Th1\\/Th17': '5.8', 'Memory CD4 T-cell Th17': '8.8', 'Memory CD4 T-cell Th2': '10.5', 'Non-Vd2 gdTCR': '6.8', 'Memory CD4 T-cell Th1': '7.1', 'Memory CD4 T-cell TFH': '7.0', 'Terminal effector memory CD4 T-cell': '3.2', 'Central memory CD8 T-cell': '6.7', 'Effector memory CD8 T-cell': '11.4', 'Terminal effector memory CD8 T-cell': '4.9', 'Non-switched memory B-cell': '5.4', 'Plasmablast': '30.3', 'Switched memory B-cell': '9.2', 'Exhausted memory B-cell': '12.2', 'Progenitor cell': '8.9', 'Memory T-reg': '18.9', 'Naive CD4 T-cell activated': '1.9', 'Naive CD8 T-cell activated': '2.2', 'Naive T-reg': '5.7'}
|
3NRX, 3NRY, 4L3I, 4L6Y, 5KMG, 7VBG
|
{'Adipose Tissue': 4.147858471760798, 'Adrenal Gland': 2.6710627906976745, 'Bladder': 3.1262857142857143, 'Blood': 13.149674854682454, 'Blood Vessel': 5.947328838951311, 'Brain': 4.31794242997729, 'Breast': 4.309821350762528, 'Cervix Uteri': 4.6506842105263155, 'Colon': 4.7497498074454425, 'Esophagus': 8.736843598615916, 'Fallopian Tube': 4.434555555555556, 'Heart': 1.5854587340301975, 'Kidney': 1.5213134831460673, 'Liver': 1.0593992477876106, 'Lung': 6.157918685121107, 'Muscle': 1.129561892901619, 'Nerve': 5.434959612277868, 'Ovary': 6.205122222222222, 'Pancreas': 1.7725213414634144, 'Pituitary': 2.0718671378091873, 'Prostate': 2.9573167346938773, 'Salivary Gland': 5.272641975308642, 'Skin': 25.474678828081817, 'Small Intestine': 6.994807486631016, 'Spleen': 6.059149377593362, 'Stomach': 4.9196, 'Testis': 37.2926648199446, 'Thyroid': 3.203790045941807, 'Uterus': 4.478767605633803, 'Vagina': 9.09873076923077}
|
RNF2
|
MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCSNASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
|
Homo sapiens
|
Nucleus, Cytoplasm, Chromosome
|
Low tissue specificity
|
{'Ciliated cells': '10.3', 'Basal respiratory cells': '9.2', 'Club cells': '8.2', 'Ionocytes': '8.1', 'Mucus glandular cells': '9.5', 'Serous glandular cells': '6.1', 'Gastric mucus-secreting cells': '10.0', 'Proximal enterocytes': '3.3', 'Paneth cells': '13.8', 'Distal enterocytes': '9.7', 'Intestinal goblet cells': '9.6', 'Exocrine glandular cells': '-0.679', 'Basal prostatic cells': '15.5', 'Prostatic glandular cells': '9.1', 'Breast glandular cells': '0.377', 'Breast myoepithelial cells': '0.381', 'Glandular and luminal cells': '10.5', 'Secretory cells': '14.7', 'Basal keratinocytes': '16.2', 'Suprabasal keratinocytes': '14.8', 'Basal squamous epithelial cells': '19.5', 'Squamous epithelial cells': '13.5', 'Alveolar cells type 1': '0.010', 'Alveolar cells type 2': '-0.229', 'Salivary duct cells': '7.0', 'Ductal cells': '0.627', 'Hepatocytes': '0.397', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.117', 'Distal tubular cells': '12.3', 'Collecting duct cells': '11.7', 'Mesothelial cells': '0.263', 'Sertoli cells': '0.556', 'Granulosa cells': '12.5', 'Enteroendocrine cells': '16.3', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '0.524', 'Excitatory neurons': '22.3', 'Inhibitory neurons': '19.7', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '5.1', 'Bipolar cells': '9.2', 'Horizontal cells': '5.0', 'Astrocytes': '10.8', 'Oligodendrocyte precursor cells': '17.5', 'Oligodendrocytes': '14.0', 'Microglial cells': '19.7', 'Muller glia cells': '12.5', 'Schwann cells': '0.108', 'Spermatogonia': '0.753', 'Spermatocytes': '0.538', 'Early spermatids': '-0.148', 'Late spermatids': '-0.521', 'Oocytes': '73.5', 'Cytotrophoblasts': '26.2', 'Syncytiotrophoblasts': '30.9', 'Extravillous trophoblasts': '55.1', 'Endothelial cells': '16.2', 'Lymphatic endothelial cells': '15.5', 'Cardiomyocytes': '0.512', 'Skeletal myocytes': '0.108', 'Smooth muscle cells': '11.7', 'Adipocytes': '21.4', 'Melanocytes': '0.202', 'Fibroblasts': '14.7', 'Peritubular cells': '0.368', 'Endometrial stromal cells': '9.8', 'Ovarian stromal cells': '9.6', 'Undifferentiated cells': '12.6', 'T-cells': '19.6', 'B-cells': '23.3', 'Plasma cells': '11.4', 'Nk-cells': '18.5', 'Granulocytes': '17.4', 'Monocytes': '34.7', 'Macrophages': '21.1', 'Hofbauer cells': '19.1', 'Kupffer cells': '19.0', 'Dendritic cells': '16.3', 'Langerhans cells': '0.301', 'Erythroid cells': '-0.005', 'Adipocytes (Subcutaneous)': '-0.322', 'Adipocytes (Visceral)': '-0.403', 'Breast glandular cells (progenitors)': '0.181', 'Adipocytes (Breast)': '-0.388', 'Colon enterocytes': '-0.081', 'Colon enteroendocrine cells': '0.295', 'Enteric glia cells': '0.348', 'Mitotic cells (Colon)': '0.078', 'Mitotic cells (Heart)': '0.545', 'Podocytes': '0.074', 'Ascending Loop of Henle cells': '0.340', 'Intercalated cells': '0.031', 'Cholangiocyte': '0.369', 'NK-cells (Liver)': '-0.229', 'Respiratory ciliated cells': '0.045', 'Mitotic cells (Lung)': '0.152', 'NK-cells (Lung)': '0.185', 'B-cells (Lung)': '-0.001', 'Alpha cells': '0.344', 'Beta cells': '0.171', 'Prostate glandular cells': '-0.111', 'Prostate basal glandular cells': '0.270', 'Urothelial cells': '0.303', 'Keratinocyte (other)': '0.333', 'Keratinocyte (granular)': '-0.224', 'Hair cortex cells': '-0.027', 'Inner root sheath cells': '0.056', 'Outer root sheath cells': '0.273', 'Sebaceous gland cells': '0.148', 'Eccrine sweat gland cells': '0.055', 'Adipocytes (Skin)': '-0.182', 'Mitotic cells (Skin)': '0.417', 'Parietal cells': '-0.540', 'Chief cells': '-0.337', 'Gastric mucous cells': '-0.356', 'Gastric enteroendocrine cells': '-0.198', 'Mitotic cells (Stomach)': '0.063', 'Parafollicular cells': '0.103', 'Thyroid glandular cells': '0.483', 'Mitotic cells (Thyroid)': '0.083', 'Adrenal cortex cells': '0.545', 'Adrenal medulla cells': '0.030', 'Mitotic cells (Adrenal gland)': '0.423', 'Minor salivary glandular cells': '0.528', 'Minor salivary gland ductal cells': '0.124', 'Minor salivary gland basal cells': '0.304', 'Mitotic cells (Minor salivary gland)': '0.331', 'Adipocytes (Minor salivary gland)': '0.149', 'Somatotropes': '0.101', 'Lactotropes': '0.148', 'Gonadotropes': '0.224', 'Corticotropes': '-0.067', 'Thyrotropes': '0.262', 'Undifferentiated cells (Pituitary gland)': '0.209', 'Mitotic cells (Spleen)': '-0.122', 'Platelets': '-0.165', 'Erythrocytes': '-0.137', 'Hematopoietic stem cells': '-0.183', 'B-cells (Spleen)': '0.302', 'NK-cells (Spleen)': '0.338', 'Amygdala excitatory': '46.4', 'Cerebellar inhibitory': '24.0', 'Cge interneuron': '29.4', 'Deep-layer corticothalamic and 6b': '38.6', 'Deep-layer intratelencephalic': '39.3', 'Deep-layer near-projecting': '37.9', 'Eccentric medium spiny neuron': '42.4', 'Hippocampal ca1-3': '47.5', 'Hippocampal ca4': '35.3', 'Hippocampal dentate gyrus': '44.7', 'Lamp5-lhx6 and chandelier': '30.0', 'Lower rhombic lip': '30.5', 'Mammillary body': '45.5', 'Medium spiny neuron': '35.3', 'Mge interneuron': '35.6', 'Midbrain-derived inhibitory': '23.2', 'Miscellaneous': '36.5', 'Splatter': '35.0', 'Thalamic excitatory': '29.8', 'Upper rhombic lip': '34.1', 'Upper-layer intratelencephalic': '48.8', 'Astrocyte': '14.5', 'Bergmann glia': '35.0', 'Central nervous system macrophage': '73.5', 'Choroid plexus epithelial cell': '19.0', 'Committed oligodendrocyte precursor': '46.0', 'Ependymal cell': '20.1', 'Oligodendrocyte': '25.6', 'Oligodendrocyte precursor cell': '39.1', 'Endothelial cell': '47.6', 'Pericyte': '33.0', 'Vascular associated smooth muscle cell': '23.0', 'Fibroblast': '21.1', 'Leukocyte': '51.4', 'Basophil': '101.9', 'Eosinophil': '27.9', 'Neutrophil': '47.4', 'Classical monocyte': '13.6', 'Non-classical monocyte': '32.3', 'Intermediate monocyte': '73.3', 'T-reg': '46.2', 'GdT-cell': '17.2', 'MAIT T-cell': '57.0', 'Memory CD4 T-cell': '15.6', 'Naive CD4 T-cell': '20.3', 'Memory CD8 T-cell': '15.8', 'Naive CD8 T-cell': '18.0', 'Memory B-cell': '20.3', 'Naive B-cell': '18.4', 'Plasmacytoid DC': '66.4', 'Myeloid DC': '90.7', 'NK-cell': '16.3', 'Total PBMC': '53.4', 'Vd2 gdTCR': '60.0', 'Memory CD4 T-cell Th1\\/Th17': '23.5', 'Memory CD4 T-cell Th17': '17.1', 'Memory CD4 T-cell Th2': '17.7', 'Non-Vd2 gdTCR': '57.8', 'Memory CD4 T-cell Th1': '16.7', 'Memory CD4 T-cell TFH': '14.3', 'Terminal effector memory CD4 T-cell': '45.2', 'Central memory CD8 T-cell': '53.5', 'Effector memory CD8 T-cell': '44.4', 'Terminal effector memory CD8 T-cell': '64.0', 'Non-switched memory B-cell': '50.8', 'Plasmablast': '43.8', 'Switched memory B-cell': '61.9', 'Exhausted memory B-cell': '61.1', 'Progenitor cell': '65.3', 'Memory T-reg': '11.6', 'Naive CD4 T-cell activated': '28.0', 'Naive CD8 T-cell activated': '38.2', 'Naive T-reg': '25.6'}
|
2H0D, 3GS2, 3H8H, 3IXS, 3RPG, 4R8P, 4S3O, 6WI7, 6WI8, 7ND1, 8GRM, 8PP7
|
{'Adipose Tissue': 10.022729235880398, 'Adrenal Gland': 6.488381007751938, 'Bladder': 10.247619047619049, 'Blood': 5.632639397201292, 'Blood Vessel': 7.217078651685393, 'Brain': 5.188003292959879, 'Breast': 10.565653594771245, 'Cervix Uteri': 12.314157894736844, 'Colon': 6.602694480102696, 'Esophagus': 6.031604844290658, 'Fallopian Tube': 9.355777777777778, 'Heart': 2.932281300813008, 'Kidney': 4.691258426966292, 'Liver': 2.186204424778761, 'Lung': 8.184290657439448, 'Muscle': 3.320568119551681, 'Nerve': 9.991290791599354, 'Ovary': 10.51105, 'Pancreas': 3.3799509146341467, 'Pituitary': 7.600116607773852, 'Prostate': 8.507763265306123, 'Salivary Gland': 7.0504691358024685, 'Skin': 9.779033167495854, 'Small Intestine': 6.162860962566844, 'Spleen': 7.747244813278009, 'Stomach': 5.053721448467967, 'Testis': 15.068869806094185, 'Thyroid': 9.285237366003065, 'Uterus': 12.214992957746478, 'Vagina': 10.894019230769231}
|
[53.31, 74.6, 84.9, 86.04, 86.7, 89.37, 90.52, 89.38, 90.34, 91.81, 90.92, 93.47, 92.96, 92.84, 93.07, 92.97, 93.93, 93.17, 93.0, 91.94, 93.2, 92.1, 90.25, 91.99, 91.73, 92.97, 90.53, 90.39, 91.87, 89.43, 86.6, 90.67, 89.69, 88.59, 90.26, 90.54, 92.47, 91.85, 92.77, 92.34, 93.32, 93.95, 94.05, 93.53, 95.54, 94.55, 94.53, 94.39, 95.31, 95.37, 95.64, 96.6, 96.11, 95.9, 95.97, 95.93, 94.59, 94.69, 95.43, 95.74, 94.61, 94.39, 95.1, 95.19, 94.64, 94.21, 95.36, 94.77, 93.77, 94.02, 95.25, 93.77, 92.64, 94.09, 95.0, 94.04, 92.23, 93.32, 93.85, 91.74, 90.84, 92.4, 91.18, 87.45, 87.28, 84.44, 75.8, 76.23, 71.15, 69.55, 65.13, 67.42, 64.22, 73.94, 89.65, 91.58, 91.16, 91.21, 91.78, 92.85, 92.23, 91.29, 92.24, 93.22, 92.95, 92.48, 94.26, 95.21, 94.55, 93.8, 94.87, 95.88, 94.33, 94.56, 94.94, 95.72, 94.88, 93.88, 95.25, 95.94, 95.08, 94.83, 96.14, 96.44, 95.23, 95.55, 96.8, 96.32, 94.91, 94.29, 95.61, 94.89, 93.82, 93.6, 94.71, 93.7, 92.74, 92.22, 90.7, 90.49, 88.75, 86.74, 84.72, 81.18, 83.58, 86.39, 90.41, 91.0, 91.24, 92.02, 92.25, 93.18, 94.33, 95.22, 95.57, 95.85, 97.15, 96.66, 96.17, 97.19, 97.58, 96.98, 96.97, 97.04, 97.74, 96.43, 95.92, 96.5, 96.93, 96.38, 96.12, 96.45, 96.78, 97.06, 96.35, 97.06, 97.19, 96.93, 97.0, 97.69, 97.48, 96.56, 95.98, 95.92, 96.09, 94.34, 93.13, 93.52, 92.18, 92.76, 93.33, 94.74, 92.19, 94.22, 93.29, 94.44, 95.67, 94.59, 93.36, 93.97, 93.5, 90.44, 90.29, 89.13, 88.25, 85.75, 89.2, 90.77, 91.89, 94.8, 94.91, 95.78, 96.09, 95.49, 96.33, 97.47, 97.02, 96.88, 97.79, 97.62, 97.25, 97.9, 97.68, 97.22, 97.05, 97.43, 96.89, 95.64, 95.35, 95.71, 96.05, 94.62, 95.59, 96.53, 96.68, 96.82, 97.17, 97.22, 97.57, 97.31, 96.91, 97.12, 96.66, 95.27, 96.1, 96.16, 96.05, 94.86, 94.43, 94.43, 94.28, 92.57, 94.1, 91.67, 92.41, 91.77, 92.9, 91.23, 90.3, 91.19, 90.29, 88.8, 90.63, 90.15, 89.89, 90.22, 91.46, 92.07, 91.55, 92.35, 94.79, 94.34, 95.32, 96.11, 97.13, 97.02, 97.07, 96.07, 97.36, 97.58, 96.62, 96.45, 95.99, 95.25, 95.31, 94.72, 94.53, 94.9, 94.29, 95.03, 95.85, 95.6, 96.28, 96.69, 96.19, 97.03, 96.67, 96.73, 96.97, 96.64, 96.61, 95.92, 95.3, 94.37, 95.09, 93.91, 91.81, 90.26, 89.31, 89.14, 90.12, 90.84, 90.42, 90.31, 92.92, 92.21, 92.38, 94.08, 92.37, 93.93, 93.04, 90.47, 92.87, 91.03, 92.21, 92.99, 93.01, 91.98, 94.87, 96.19, 95.96, 96.0, 96.83, 97.39, 96.35, 96.91, 96.07, 96.8, 97.1, 95.64, 94.7, 95.34, 94.09, 91.2, 92.93, 93.08, 89.88, 88.37, 90.57, 89.99, 90.56, 91.93, 92.32, 92.09, 92.24, 92.28, 93.34, 94.14, 91.71, 93.54, 94.18, 94.39, 93.75, 92.49, 93.12, 91.9, 91.22, 90.53, 89.33, 87.64, 86.75, 86.27, 83.9, 82.77, 77.04, 78.09, 79.28, 76.15, 72.54, 62.21, 56.53, 65.61, 70.9, 81.59, 83.1, 84.66, 84.94, 88.88, 86.59, 90.34, 90.26, 91.18, 91.7, 92.43, 92.96, 90.97, 92.58, 92.37, 93.47, 93.41, 92.58, 92.68, 93.67, 93.24, 91.99, 92.77, 93.18, 92.81, 90.42, 91.47, 91.63, 90.6, 90.44, 90.91, 90.36, 88.72, 84.62, 86.3, 83.0, 84.79, 85.91, 84.18, 85.74, 82.87, 84.09, 86.86, 89.82, 89.83, 91.4, 91.54, 89.42, 91.78, 92.36, 91.33, 91.83, 92.79, 92.36, 91.27, 90.83, 90.9, 91.71, 89.92, 89.0, 88.7, 89.21, 88.37, 88.2, 88.8, 88.01, 83.63, 85.67, 86.6, 85.99, 82.23, 84.63, 83.4, 80.37, 78.47, 81.09, 78.8, 78.13, 77.08, 75.24, 72.54, 58.17, 56.31, 49.52, 50.84, 46.56, 44.31, 52.78, 41.14, 43.14, 40.63, 39.64, 38.83, 46.21, 44.39, 50.09, 46.93, 51.65, 43.95, 42.7, 44.35, 43.45, 44.27, 43.15, 51.43, 44.92, 39.72, 44.96, 40.71, 43.1, 38.53, 43.03, 41.53, 43.48, 39.1, 41.22, 42.0, 40.8, 42.85, 50.43, 49.85, 41.5, 41.83, 37.27, 35.06, 44.53, 45.16, 46.43, 43.35, 42.9, 56.34, 50.32, 50.66, 43.77, 48.21, 54.42, 50.96, 39.73, 41.79, 42.52, 39.25, 45.93, 36.07, 35.26, 32.22, 34.46, 38.57, 36.64, 44.17, 41.96, 47.32, 42.52, 48.1, 45.04, 41.14, 43.92, 34.45, 37.48, 36.01, 31.14, 32.43, 32.62, 34.91, 31.99, 34.44, 33.73, 32.06, 32.08, 31.98, 32.7, 31.19, 30.76, 38.48, 33.09, 34.84, 33.5, 34.17, 40.17, 30.73, 32.47, 32.45, 30.58, 35.21, 32.34, 34.79, 33.46, 31.33, 34.13, 30.12, 31.1, 32.14, 35.58, 34.7, 37.56, 46.29, 40.25, 52.47, 44.59, 44.36, 45.32, 39.7, 35.96, 40.42, 37.26, 31.13, 32.62, 29.96, 34.06, 30.61, 33.76, 34.02, 34.76, 39.3, 35.91, 36.18, 35.97, 37.91, 40.12, 39.4, 37.6, 39.85, 39.02, 40.68, 39.38, 40.26, 40.13, 41.09, 42.89, 42.37, 43.04, 41.64, 39.92, 43.38, 41.37, 42.12, 44.72, 40.59]
|
[0.66, 0.73, 0.87, 0.66, 0.4, 0.37, 0.61, 0.43, 0.49, 0.59, 0.51, 0.65, 0.43, 0.61, 0.38, 0.57, 0.65, 0.47, 0.39, 0.52, 0.54, 0.32, 0.58, 0.56, 0.41, 0.1, 0.46, 0.87, 0.66, 0.68, 0.15, 0.55, 0.64, 0.59, 0.43, 0.11, 0.61, 0.59, 0.4, 0.32, 0.51, 0.53, 0.33, 0.57, 0.58, 0.59, 0.33, 0.59, 0.46, 0.56, 0.5, 0.44, 0.5, 0.49, 0.63, 0.56, 0.51, 0.43, 0.46, 0.4, 0.21, 0.45, 0.67, 0.55, 0.17, 0.49, 0.7, 0.23, 0.11, 0.4, 0.56, 0.09, 0.33, 0.67, 0.27, 0.04, 0.55, 0.52, 0.04, 0.06, 0.65, 0.29, 0.01, 0.73, 0.33, 0.9, 0.61, 0.39, 0.82, 0.49, 0.86, 0.67, 0.98, 0.41, 0.65, 0.45, 0.55, 0.38, 0.14, 0.09, 0.55, 0.31, 0.02, 0.44, 0.53, 0.21, 0.02, 0.54, 0.48, 0.04, 0.48, 0.56, 0.3, 0.24, 0.62, 0.48, 0.1, 0.3, 0.56, 0.32, 0.02, 0.57, 0.52, 0.08, 0.29, 0.49, 0.24, 0.03, 0.5, 0.52, 0.03, 0.02, 0.55, 0.25, 0.01, 0.72, 0.47, 0.88, 0.6, 0.3, 0.96, 0.17, 0.53, 0.55, 0.74, 0.47, 0.11, 0.02, 0.17, 0.52, 0.66, 0.43, 0.0, 0.43, 0.52, 0.01, 0.33, 0.66, 0.3, 0.0, 0.44, 0.49, 0.09, 0.46, 0.61, 0.35, 0.24, 0.56, 0.6, 0.13, 0.31, 0.72, 0.34, 0.0, 0.36, 0.49, 0.1, 0.09, 0.72, 0.39, 0.0, 0.32, 0.54, 0.07, 0.04, 0.57, 0.31, 0.12, 0.46, 0.31, 0.89, 0.25, 0.67, 0.51, 0.56, 0.24, 0.08, 0.43, 0.43, 0.0, 0.28, 0.72, 0.61, 0.78, 0.36, 0.7, 0.73, 0.09, 0.37, 0.05, 0.13, 0.63, 0.75, 0.26, 0.07, 0.47, 0.34, 0.0, 0.29, 0.59, 0.11, 0.11, 0.54, 0.56, 0.05, 0.45, 0.55, 0.43, 0.43, 0.49, 0.55, 0.19, 0.41, 0.62, 0.38, 0.0, 0.36, 0.43, 0.09, 0.04, 0.39, 0.36, 0.0, 0.38, 0.62, 0.05, 0.09, 0.62, 0.58, 0.23, 0.82, 0.1, 0.49, 0.61, 0.75, 0.43, 0.21, 0.67, 0.63, 0.16, 0.44, 0.71, 0.23, 0.19, 0.6, 0.51, 0.17, 0.36, 0.47, 0.75, 0.19, 0.4, 0.69, 0.28, 0.0, 0.44, 0.64, 0.1, 0.04, 0.48, 0.46, 0.0, 0.38, 0.48, 0.32, 0.2, 0.32, 0.48, 0.42, 0.15, 0.28, 0.7, 0.46, 0.0, 0.43, 0.48, 0.08, 0.11, 0.64, 0.35, 0.0, 0.35, 0.56, 0.2, 0.03, 0.51, 0.32, 0.03, 0.14, 0.13, 0.13, 0.63, 0.76, 0.37, 0.22, 0.63, 0.71, 0.11, 0.66, 0.24, 0.28, 0.83, 0.29, 0.79, 0.71, 0.17, 0.43, 0.45, 0.54, 0.07, 0.2, 0.59, 0.49, 0.0, 0.41, 0.56, 0.14, 0.05, 0.56, 0.49, 0.0, 0.32, 0.57, 0.27, 0.13, 0.6, 0.82, 0.11, 0.31, 0.64, 0.06, 0.03, 0.51, 0.14, 0.02, 0.4, 0.46, 0.0, 0.25, 0.51, 0.1, 0.02, 0.57, 0.46, 0.0, 0.37, 0.33, 0.11, 0.06, 0.68, 0.39, 0.34, 0.36, 0.43, 0.81, 0.63, 0.13, 0.79, 0.75, 0.69, 0.95, 0.79, 0.65, 0.43, 0.37, 0.62, 0.63, 0.15, 0.32, 0.66, 0.46, 0.22, 0.37, 0.61, 0.09, 0.47, 0.72, 0.35, 0.0, 0.39, 0.66, 0.08, 0.13, 0.68, 0.41, 0.03, 0.45, 0.54, 0.34, 0.06, 0.46, 0.61, 0.11, 0.35, 0.7, 0.85, 0.38, 0.79, 0.69, 0.35, 0.02, 0.5, 0.12, 0.61, 0.56, 0.33, 0.43, 0.03, 0.35, 0.44, 0.32, 0.04, 0.52, 0.5, 0.27, 0.26, 0.39, 0.59, 0.18, 0.61, 0.48, 0.49, 0.36, 0.4, 0.54, 0.36, 0.45, 0.59, 0.51, 0.55, 0.57, 0.5, 0.54, 0.59, 0.54, 0.57, 0.52, 0.48, 0.47, 0.47, 0.41, 0.79, 0.9, 0.87, 0.5, 0.6, 0.81, 0.76, 0.91, 0.84, 0.92, 0.97, 0.97, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.93, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.95, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 0.96, 0.95, 0.86, 0.86, 0.84, 0.81, 0.82, 0.93, 0.84, 0.96, 0.84, 0.78, 0.84, 0.74, 0.66, 0.78, 0.73, 0.61, 0.79, 0.83, 0.84, 0.89, 0.81, 0.95, 0.86, 1.0, 0.76, 0.9, 0.89, 0.8, 0.9, 0.88, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0]
|
[40.88, 45.94, 40.18, 42.25, 46.47, 35.96, 45.34, 53.01, 61.54, 81.06, 89.46, 92.49, 92.15, 93.84, 94.54, 94.51, 95.65, 96.23, 97.19, 96.72, 97.48, 97.55, 97.56, 97.38, 96.33, 97.07, 97.04, 97.33, 96.0, 95.85, 93.47, 93.42, 92.43, 90.49, 87.27, 89.85, 86.99, 87.84, 86.65, 85.82, 83.3, 82.42, 76.63, 84.24, 86.37, 83.65, 87.99, 92.79, 93.1, 93.45, 96.92, 96.01, 95.94, 94.97, 92.73, 91.13, 91.86, 95.67, 95.02, 97.14, 97.87, 97.89, 98.11, 97.49, 96.41, 94.55, 96.45, 97.06, 97.83, 98.15, 98.2, 98.15, 97.65, 97.38, 97.52, 96.68, 94.95, 95.12, 94.52, 93.75, 92.29, 90.8, 83.07, 86.12, 92.61, 95.28, 96.77, 95.32, 95.78, 96.21, 94.85, 94.02, 94.91, 94.71, 91.18, 90.71, 92.19, 94.21, 95.09, 96.82, 97.3, 98.06, 97.98, 97.79, 97.44, 96.68, 95.93, 95.6, 93.82, 93.32, 92.41, 91.61, 89.93, 88.52, 85.23, 83.98, 80.23, 80.92, 81.11, 79.66, 82.1, 83.23, 81.11, 78.9, 83.78, 82.2, 79.35, 80.82, 80.66, 71.44, 75.84, 75.7, 70.96, 65.68, 67.13, 66.23, 69.15, 69.54, 72.82, 75.88, 80.97, 82.96, 85.62, 87.58, 89.76, 88.41, 89.13, 91.99, 91.09, 88.44, 88.69, 89.93, 86.97, 85.66, 87.21, 79.07, 74.24, 67.59, 61.38, 60.81, 54.89, 52.35, 51.63, 55.04, 52.76, 50.77, 42.11, 41.56, 38.46, 45.38, 47.48, 48.49, 51.62, 43.2, 41.3, 49.63, 50.45, 43.2, 42.68, 42.77, 41.52, 39.56, 42.05, 42.33, 42.83, 39.47, 41.42, 45.74, 41.21, 40.59, 36.41, 40.86, 39.42, 41.72, 39.77, 36.71, 38.41, 35.63, 40.98, 40.92, 41.91, 41.29, 45.06, 38.81, 48.62, 36.56, 46.89, 38.14, 38.04, 37.14, 35.71, 34.06, 34.24, 37.08, 34.55, 41.53, 38.69, 40.09, 41.59, 43.49, 42.81, 47.66, 54.32, 69.12, 83.63, 87.64, 92.05, 93.54, 94.46, 93.86, 93.62, 92.73, 91.96, 87.81, 86.48, 86.35, 81.65, 70.31, 66.79, 64.1, 54.49, 61.66, 72.1, 80.89, 90.26, 91.37, 94.07, 93.26, 91.87, 91.52, 89.87, 88.17, 89.05, 92.8, 95.08, 95.04, 94.5, 94.51, 93.76, 92.98, 92.19, 93.23, 91.23, 89.98, 89.21, 89.11, 86.3, 85.03, 84.1, 84.54, 80.18, 79.39, 80.66, 74.97, 66.8, 58.44, 56.74, 48.87, 50.78, 52.11, 49.57, 59.24, 67.72, 69.26, 75.55, 77.25, 85.41, 81.71, 83.09, 85.04, 91.11, 93.48, 94.61, 95.51, 94.64, 92.3, 86.45, 82.36, 83.8, 83.39, 89.48, 92.51, 93.34, 94.71, 94.51, 92.52, 91.82, 92.86, 94.83, 93.88, 93.61, 89.73, 92.15, 92.83, 90.65, 89.03, 90.21, 90.87, 89.5, 85.12, 84.32, 81.35, 86.38, 90.45, 92.69, 94.63, 95.46, 95.02, 93.9, 91.77, 89.96, 86.48, 74.39, 57.33, 36.11, 28.35]
|
[0.99, 0.96, 0.94, 0.84, 0.84, 0.93, 0.84, 0.9, 0.8, 0.91, 0.7, 0.63, 0.69, 0.73, 0.58, 0.64, 0.77, 0.59, 0.58, 0.44, 0.79, 0.64, 0.44, 0.65, 0.69, 0.65, 0.87, 0.82, 0.84, 0.87, 0.79, 0.67, 0.88, 0.73, 0.87, 0.65, 0.87, 0.78, 0.9, 0.61, 0.55, 0.36, 0.61, 0.57, 0.32, 0.32, 0.79, 0.63, 0.03, 0.25, 0.0, 0.47, 0.39, 0.44, 0.61, 0.27, 0.07, 0.03, 0.47, 0.69, 0.01, 0.08, 0.02, 0.0, 0.54, 0.69, 0.22, 0.58, 0.28, 0.36, 0.0, 0.07, 0.17, 0.75, 0.18, 0.0, 0.26, 0.49, 0.27, 0.07, 0.7, 0.72, 0.54, 0.63, 0.47, 0.34, 0.0, 0.39, 0.5, 0.4, 0.65, 0.4, 0.76, 0.0, 0.68, 0.44, 0.59, 0.8, 0.21, 0.06, 0.47, 0.7, 0.08, 0.62, 0.76, 0.13, 0.24, 0.49, 0.47, 0.08, 0.57, 0.83, 0.25, 0.18, 0.77, 0.33, 0.25, 0.72, 0.7, 0.13, 0.36, 0.4, 0.35, 0.35, 0.69, 0.6, 0.38, 0.57, 0.51, 0.33, 0.48, 0.65, 0.64, 0.47, 0.6, 0.4, 0.71, 0.77, 0.45, 0.6, 0.48, 0.61, 0.58, 0.52, 0.69, 0.51, 0.32, 0.57, 0.63, 0.51, 0.62, 0.43, 0.51, 0.51, 0.79, 0.7, 0.66, 0.77, 0.51, 0.71, 0.65, 0.74, 0.77, 0.82, 0.8, 0.86, 0.82, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.88, 0.99, 0.69, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.99, 0.98, 0.98, 1.0, 0.94, 0.93, 0.69, 0.84, 0.9, 0.83, 0.78, 0.84, 0.79, 0.8, 0.73, 0.77, 0.84, 0.78, 0.79, 0.73, 0.87, 0.83, 0.62, 0.87, 0.48, 0.21, 0.05, 0.42, 0.11, 0.57, 0.02, 0.11, 0.0, 0.31, 0.22, 0.07, 0.62, 0.87, 0.45, 0.25, 0.89, 0.97, 0.6, 0.88, 0.63, 0.27, 0.6, 0.4, 0.1, 0.79, 0.13, 0.59, 0.3, 0.36, 0.0, 0.56, 0.18, 0.19, 0.03, 0.37, 0.57, 0.04, 0.02, 0.48, 0.31, 0.0, 0.06, 0.29, 0.38, 0.27, 0.09, 0.35, 0.38, 0.42, 0.32, 0.84, 0.79, 0.63, 0.77, 0.7, 0.89, 0.6, 0.76, 0.79, 0.45, 0.4, 0.83, 0.59, 0.11, 0.29, 0.43, 0.7, 0.42, 0.2, 0.21, 0.02, 0.14, 0.0, 0.32, 0.27, 0.98, 0.67, 0.61, 0.66, 0.36, 0.3, 0.59, 0.07, 0.48, 0.15, 0.7, 0.21, 0.29, 0.0, 0.3, 0.4, 0.0, 0.31, 0.52, 0.65, 0.31, 0.19, 0.73, 0.5, 0.57, 0.76, 0.45, 0.01, 0.28, 0.0, 0.11, 0.02, 0.03, 0.51, 0.35, 0.81, 0.75, 0.95, 0.97]
| null | null | null | null |
RACGAP1,CENPE,KIF4A,KIF23 ,KIF14 , KIF20A ,PLK1 ,KIF20B
| null | null | null | null |
Homodimer
| null | 78.712903
| 0.544032
| 77.529226
| 0.549315
| 1,954
|
O43734
|
Q9Y4K3
|
19825828, BioGrid E3Net
|
UbiNet, UbiBrowser, 31181401
|
TRAF3IP2
|
MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPTMLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCSAVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSLGGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPLRSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQPALPGQPLPGASVRGLHPVQKVILNYPSPWDHEERPAQRDCSFPGLPRHQDQPHHQPPNRAGAPGESLECPAELRPQVPQPPSPAAVPRPPSNPPARGTLKTSNLPEELRKVFITYSMDTAMEVVKFVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVMIIVAISPKYKQDVEGAESQLDEDEHGLHTKYIHRMMQIEFIKQGSMNFRFIPVLFPNAKKEHVPTWLQNTHVYSWPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL
|
Homo sapiens
| null |
Low tissue specificity
|
{'Ciliated cells': '17.1', 'Basal respiratory cells': '43.3', 'Club cells': '15.8', 'Ionocytes': '22.8', 'Mucus glandular cells': '14.7', 'Serous glandular cells': '12.0', 'Gastric mucus-secreting cells': '15.9', 'Proximal enterocytes': '19.8', 'Paneth cells': '17.4', 'Distal enterocytes': '33.7', 'Intestinal goblet cells': '23.8', 'Exocrine glandular cells': '-0.640', 'Basal prostatic cells': '20.6', 'Prostatic glandular cells': '8.9', 'Breast glandular cells': '0.441', 'Breast myoepithelial cells': '0.497', 'Glandular and luminal cells': '31.6', 'Secretory cells': '45.1', 'Basal keratinocytes': '26.5', 'Suprabasal keratinocytes': '26.1', 'Basal squamous epithelial cells': '14.4', 'Squamous epithelial cells': '15.6', 'Alveolar cells type 1': '0.017', 'Alveolar cells type 2': '0.225', 'Salivary duct cells': '17.5', 'Ductal cells': '0.513', 'Hepatocytes': '0.275', 'Cholangiocytes': '9.5', 'Proximal tubular cells': '0.118', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.388', 'Sertoli cells': '0.564', 'Granulosa cells': '10.5', 'Enteroendocrine cells': '26.2', 'Pancreatic endocrine cells': '13.6', 'Leydig cells': '0.679', 'Excitatory neurons': '5.7', 'Inhibitory neurons': '10.3', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '6.7', 'Bipolar cells': '7.9', 'Horizontal cells': '3.8', 'Astrocytes': '24.8', 'Oligodendrocyte precursor cells': '18.4', 'Oligodendrocytes': '6.1', 'Microglial cells': '7.2', 'Muller glia cells': '14.1', 'Schwann cells': '-0.064', 'Spermatogonia': '0.478', 'Spermatocytes': '0.018', 'Early spermatids': '-0.629', 'Late spermatids': '-0.670', 'Oocytes': '21.3', 'Cytotrophoblasts': '20.4', 'Syncytiotrophoblasts': '24.7', 'Extravillous trophoblasts': '31.0', 'Endothelial cells': '14.9', 'Lymphatic endothelial cells': '16.6', 'Cardiomyocytes': '0.405', 'Skeletal myocytes': '-0.318', 'Smooth muscle cells': '10.0', 'Adipocytes': '25.0', 'Melanocytes': '0.235', 'Fibroblasts': '13.2', 'Peritubular cells': '0.459', 'Endometrial stromal cells': '14.9', 'Ovarian stromal cells': '7.7', 'Undifferentiated cells': '24.8', 'T-cells': '7.6', 'B-cells': '10.9', 'Plasma cells': '5.0', 'Nk-cells': '5.6', 'Granulocytes': '24.5', 'Monocytes': '5.9', 'Macrophages': '6.3', 'Hofbauer cells': '4.8', 'Kupffer cells': '4.4', 'Dendritic cells': '4.2', 'Langerhans cells': '0.264', 'Erythroid cells': '-0.045', 'Adipocytes (Subcutaneous)': '-0.272', 'Adipocytes (Visceral)': '-0.332', 'Breast glandular cells (progenitors)': '0.355', 'Adipocytes (Breast)': '-0.547', 'Colon enterocytes': '0.126', 'Colon enteroendocrine cells': '-0.065', 'Enteric glia cells': '-0.388', 'Mitotic cells (Colon)': '0.276', 'Mitotic cells (Heart)': '0.437', 'Podocytes': '-0.088', 'Ascending Loop of Henle cells': '0.248', 'Intercalated cells': '-0.105', 'Cholangiocyte': '0.367', 'NK-cells (Liver)': '-0.274', 'Respiratory ciliated cells': '-0.120', 'Mitotic cells (Lung)': '0.011', 'NK-cells (Lung)': '-0.093', 'B-cells (Lung)': '-0.057', 'Alpha cells': '0.384', 'Beta cells': '0.179', 'Prostate glandular cells': '-0.071', 'Prostate basal glandular cells': '0.297', 'Urothelial cells': '0.191', 'Keratinocyte (other)': '0.497', 'Keratinocyte (granular)': '0.156', 'Hair cortex cells': '-0.283', 'Inner root sheath cells': '-0.209', 'Outer root sheath cells': '-0.203', 'Sebaceous gland cells': '-0.213', 'Eccrine sweat gland cells': '-0.303', 'Adipocytes (Skin)': '-0.368', 'Mitotic cells (Skin)': '0.170', 'Parietal cells': '0.009', 'Chief cells': '0.174', 'Gastric mucous cells': '0.336', 'Gastric enteroendocrine cells': '0.185', 'Mitotic cells (Stomach)': '0.436', 'Parafollicular cells': '0.031', 'Thyroid glandular cells': '0.256', 'Mitotic cells (Thyroid)': '-0.019', 'Adrenal cortex cells': '0.449', 'Adrenal medulla cells': '-0.074', 'Mitotic cells (Adrenal gland)': '0.213', 'Minor salivary glandular cells': '0.500', 'Minor salivary gland ductal cells': '-0.136', 'Minor salivary gland basal cells': '0.550', 'Mitotic cells (Minor salivary gland)': '0.654', 'Adipocytes (Minor salivary gland)': '0.253', 'Somatotropes': '0.191', 'Lactotropes': '0.288', 'Gonadotropes': '0.137', 'Corticotropes': '-0.051', 'Thyrotropes': '0.199', 'Undifferentiated cells (Pituitary gland)': '-0.058', 'Mitotic cells (Spleen)': '-0.092', 'Platelets': '-0.113', 'Erythrocytes': '-0.311', 'Hematopoietic stem cells': '-0.134', 'B-cells (Spleen)': '0.610', 'NK-cells (Spleen)': '0.104', 'Amygdala excitatory': '15.2', 'Cerebellar inhibitory': '17.2', 'Cge interneuron': '30.5', 'Deep-layer corticothalamic and 6b': '13.3', 'Deep-layer intratelencephalic': '12.8', 'Deep-layer near-projecting': '19.5', 'Eccentric medium spiny neuron': '25.8', 'Hippocampal ca1-3': '12.5', 'Hippocampal ca4': '15.3', 'Hippocampal dentate gyrus': '34.7', 'Lamp5-lhx6 and chandelier': '32.5', 'Lower rhombic lip': '15.1', 'Mammillary body': '18.5', 'Medium spiny neuron': '26.3', 'Mge interneuron': '18.3', 'Midbrain-derived inhibitory': '23.2', 'Miscellaneous': '14.3', 'Splatter': '19.5', 'Thalamic excitatory': '10.5', 'Upper rhombic lip': '21.8', 'Upper-layer intratelencephalic': '13.7', 'Astrocyte': '64.1', 'Bergmann glia': '42.7', 'Central nervous system macrophage': '14.5', 'Choroid plexus epithelial cell': '33.9', 'Committed oligodendrocyte precursor': '14.5', 'Ependymal cell': '27.1', 'Oligodendrocyte': '16.6', 'Oligodendrocyte precursor cell': '60.3', 'Endothelial cell': '27.0', 'Pericyte': '30.0', 'Vascular associated smooth muscle cell': '21.4', 'Fibroblast': '17.2', 'Leukocyte': '12.1', 'Basophil': '63.3', 'Eosinophil': '4.5', 'Neutrophil': '46.3', 'Classical monocyte': '4.2', 'Non-classical monocyte': '1.0', 'Intermediate monocyte': '8.4', 'T-reg': '31.2', 'GdT-cell': '3.2', 'MAIT T-cell': '37.1', 'Memory CD4 T-cell': '5.9', 'Naive CD4 T-cell': '17.4', 'Memory CD8 T-cell': '4.1', 'Naive CD8 T-cell': '17.6', 'Memory B-cell': '5.2', 'Naive B-cell': '16.8', 'Plasmacytoid DC': '12.3', 'Myeloid DC': '13.7', 'NK-cell': '6.9', 'Total PBMC': '16.6', 'Vd2 gdTCR': '22.7', 'Memory CD4 T-cell Th1\\/Th17': '15.3', 'Memory CD4 T-cell Th17': '17.8', 'Memory CD4 T-cell Th2': '16.9', 'Non-Vd2 gdTCR': '12.8', 'Memory CD4 T-cell Th1': '16.3', 'Memory CD4 T-cell TFH': '18.7', 'Terminal effector memory CD4 T-cell': '12.4', 'Central memory CD8 T-cell': '28.1', 'Effector memory CD8 T-cell': '17.3', 'Terminal effector memory CD8 T-cell': '12.2', 'Non-switched memory B-cell': '36.2', 'Plasmablast': '16.1', 'Switched memory B-cell': '35.4', 'Exhausted memory B-cell': '29.2', 'Progenitor cell': '31.6', 'Memory T-reg': '27.1', 'Naive CD4 T-cell activated': '9.2', 'Naive CD8 T-cell activated': '6.4', 'Naive T-reg': '19.2'}
| null |
{'Adipose Tissue': 16.178859634551497, 'Adrenal Gland': 10.648298449612405, 'Bladder': 13.349571428571428, 'Blood': 5.067170075349838, 'Blood Vessel': 14.427770786516854, 'Brain': 3.87176279333838, 'Breast': 17.668021786492375, 'Cervix Uteri': 22.36315789473684, 'Colon': 9.98039024390244, 'Esophagus': 12.739903806228371, 'Fallopian Tube': 17.19222222222222, 'Heart': 3.424847619047619, 'Kidney': 5.352842696629214, 'Liver': 2.2451721238938056, 'Lung': 13.237, 'Muscle': 4.831343212951432, 'Nerve': 7.00324071082391, 'Ovary': 10.12803888888889, 'Pancreas': 5.324411585365853, 'Pituitary': 11.268356890459364, 'Prostate': 13.232, 'Salivary Gland': 15.207932098765433, 'Skin': 25.45951851851852, 'Small Intestine': 10.093, 'Spleen': 4.634705394190871, 'Stomach': 12.228754874651807, 'Testis': 2.127772299168975, 'Thyroid': 13.504326186830015, 'Uterus': 27.74687323943662, 'Vagina': 18.538064102564103}
|
TRAF6
|
MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
|
Homo sapiens
|
Cytoplasm, Cytoplasm, cell cortex, Nucleus, Lipid droplet
|
Low tissue specificity
|
{'Ciliated cells': '6.4', 'Basal respiratory cells': '6.8', 'Club cells': '5.5', 'Ionocytes': '5.5', 'Mucus glandular cells': '11.3', 'Serous glandular cells': '3.8', 'Gastric mucus-secreting cells': '5.9', 'Proximal enterocytes': '10.4', 'Paneth cells': '10.8', 'Distal enterocytes': '8.8', 'Intestinal goblet cells': '7.1', 'Exocrine glandular cells': '-0.576', 'Basal prostatic cells': '7.5', 'Prostatic glandular cells': '6.3', 'Breast glandular cells': '0.445', 'Breast myoepithelial cells': '0.568', 'Glandular and luminal cells': '10.9', 'Secretory cells': '11.2', 'Basal keratinocytes': '10.3', 'Suprabasal keratinocytes': '10.4', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '9.5', 'Alveolar cells type 1': '0.203', 'Alveolar cells type 2': '-0.506', 'Salivary duct cells': '9.2', 'Ductal cells': '0.661', 'Hepatocytes': '0.350', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '0.239', 'Distal tubular cells': '6.1', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.382', 'Sertoli cells': '0.613', 'Granulosa cells': '8.0', 'Enteroendocrine cells': '9.1', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.475', 'Excitatory neurons': '28.0', 'Inhibitory neurons': '23.0', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '3.8', 'Bipolar cells': '6.0', 'Horizontal cells': '5.7', 'Astrocytes': '12.4', 'Oligodendrocyte precursor cells': '10.4', 'Oligodendrocytes': '27.1', 'Microglial cells': '17.0', 'Muller glia cells': '5.3', 'Schwann cells': '0.103', 'Spermatogonia': '0.568', 'Spermatocytes': '0.352', 'Early spermatids': '-0.180', 'Late spermatids': '-0.584', 'Oocytes': '15.4', 'Cytotrophoblasts': '7.0', 'Syncytiotrophoblasts': '8.0', 'Extravillous trophoblasts': '6.8', 'Endothelial cells': '14.2', 'Lymphatic endothelial cells': '7.0', 'Cardiomyocytes': '0.541', 'Skeletal myocytes': '-0.347', 'Smooth muscle cells': '9.5', 'Adipocytes': '10.0', 'Melanocytes': '0.183', 'Fibroblasts': '10.0', 'Peritubular cells': '0.503', 'Endometrial stromal cells': '7.0', 'Ovarian stromal cells': '6.9', 'Undifferentiated cells': '5.3', 'T-cells': '11.8', 'B-cells': '13.4', 'Plasma cells': '9.4', 'Nk-cells': '11.3', 'Granulocytes': '11.4', 'Monocytes': '13.9', 'Macrophages': '10.3', 'Hofbauer cells': '7.1', 'Kupffer cells': '8.3', 'Dendritic cells': '14.9', 'Langerhans cells': '0.146', 'Erythroid cells': '0.147', 'Adipocytes (Subcutaneous)': '-0.302', 'Adipocytes (Visceral)': '-0.406', 'Breast glandular cells (progenitors)': '0.305', 'Adipocytes (Breast)': '-0.577', 'Colon enterocytes': '-0.139', 'Colon enteroendocrine cells': '0.257', 'Enteric glia cells': '0.217', 'Mitotic cells (Colon)': '-0.030', 'Mitotic cells (Heart)': '0.497', 'Podocytes': '-0.011', 'Ascending Loop of Henle cells': '0.339', 'Intercalated cells': '-0.002', 'Cholangiocyte': '0.347', 'NK-cells (Liver)': '-0.103', 'Respiratory ciliated cells': '0.122', 'Mitotic cells (Lung)': '-0.196', 'NK-cells (Lung)': '0.500', 'B-cells (Lung)': '0.277', 'Alpha cells': '0.409', 'Beta cells': '0.273', 'Prostate glandular cells': '-0.375', 'Prostate basal glandular cells': '0.074', 'Urothelial cells': '0.226', 'Keratinocyte (other)': '0.355', 'Keratinocyte (granular)': '-0.010', 'Hair cortex cells': '-0.236', 'Inner root sheath cells': '-0.099', 'Outer root sheath cells': '-0.029', 'Sebaceous gland cells': '-0.094', 'Eccrine sweat gland cells': '-0.078', 'Adipocytes (Skin)': '-0.234', 'Mitotic cells (Skin)': '0.239', 'Parietal cells': '-0.555', 'Chief cells': '-0.555', 'Gastric mucous cells': '-0.311', 'Gastric enteroendocrine cells': '-0.367', 'Mitotic cells (Stomach)': '0.006', 'Parafollicular cells': '0.019', 'Thyroid glandular cells': '0.187', 'Mitotic cells (Thyroid)': '0.016', 'Adrenal cortex cells': '0.446', 'Adrenal medulla cells': '-0.039', 'Mitotic cells (Adrenal gland)': '0.319', 'Minor salivary glandular cells': '0.547', 'Minor salivary gland ductal cells': '0.222', 'Minor salivary gland basal cells': '0.378', 'Mitotic cells (Minor salivary gland)': '0.451', 'Adipocytes (Minor salivary gland)': '0.237', 'Somatotropes': '-0.077', 'Lactotropes': '-0.152', 'Gonadotropes': '0.084', 'Corticotropes': '-0.155', 'Thyrotropes': '0.072', 'Undifferentiated cells (Pituitary gland)': '0.177', 'Mitotic cells (Spleen)': '-0.147', 'Platelets': '-0.236', 'Erythrocytes': '-0.054', 'Hematopoietic stem cells': '-0.292', 'B-cells (Spleen)': '0.241', 'NK-cells (Spleen)': '0.337', 'Amygdala excitatory': '39.9', 'Cerebellar inhibitory': '21.9', 'Cge interneuron': '26.6', 'Deep-layer corticothalamic and 6b': '36.9', 'Deep-layer intratelencephalic': '41.9', 'Deep-layer near-projecting': '37.5', 'Eccentric medium spiny neuron': '29.9', 'Hippocampal ca1-3': '42.5', 'Hippocampal ca4': '24.3', 'Hippocampal dentate gyrus': '33.6', 'Lamp5-lhx6 and chandelier': '26.6', 'Lower rhombic lip': '36.6', 'Mammillary body': '34.8', 'Medium spiny neuron': '35.1', 'Mge interneuron': '33.9', 'Midbrain-derived inhibitory': '28.8', 'Miscellaneous': '38.8', 'Splatter': '30.9', 'Thalamic excitatory': '42.6', 'Upper rhombic lip': '22.8', 'Upper-layer intratelencephalic': '38.0', 'Astrocyte': '27.1', 'Bergmann glia': '20.3', 'Central nervous system macrophage': '40.4', 'Choroid plexus epithelial cell': '33.2', 'Committed oligodendrocyte precursor': '27.5', 'Ependymal cell': '17.7', 'Oligodendrocyte': '42.0', 'Oligodendrocyte precursor cell': '21.3', 'Endothelial cell': '56.3', 'Pericyte': '36.3', 'Vascular associated smooth muscle cell': '39.5', 'Fibroblast': '26.5', 'Leukocyte': '34.8', 'Basophil': '67.3', 'Eosinophil': '34.7', 'Neutrophil': '48.8', 'Classical monocyte': '32.2', 'Non-classical monocyte': '46.0', 'Intermediate monocyte': '29.5', 'T-reg': '31.7', 'GdT-cell': '17.9', 'MAIT T-cell': '40.4', 'Memory CD4 T-cell': '15.1', 'Naive CD4 T-cell': '39.2', 'Memory CD8 T-cell': '17.5', 'Naive CD8 T-cell': '33.4', 'Memory B-cell': '17.1', 'Naive B-cell': '59.7', 'Plasmacytoid DC': '33.9', 'Myeloid DC': '24.3', 'NK-cell': '61.5', 'Total PBMC': '32.7', 'Vd2 gdTCR': '44.7', 'Memory CD4 T-cell Th1\\/Th17': '50.1', 'Memory CD4 T-cell Th17': '46.9', 'Memory CD4 T-cell Th2': '49.6', 'Non-Vd2 gdTCR': '42.7', 'Memory CD4 T-cell Th1': '43.2', 'Memory CD4 T-cell TFH': '38.6', 'Terminal effector memory CD4 T-cell': '38.2', 'Central memory CD8 T-cell': '34.8', 'Effector memory CD8 T-cell': '52.5', 'Terminal effector memory CD8 T-cell': '48.3', 'Non-switched memory B-cell': '25.2', 'Plasmablast': '30.7', 'Switched memory B-cell': '25.4', 'Exhausted memory B-cell': '24.1', 'Progenitor cell': '22.3', 'Memory T-reg': '36.7', 'Naive CD4 T-cell activated': '27.7', 'Naive CD8 T-cell activated': '25.5', 'Naive T-reg': '39.3'}
|
1LB4, 1LB5, 1LB6, 2ECI, 2JMD, 3HCS, 3HCT, 3HCU, 4Z8M, 5ZUJ, 6A33, 7L3L, 8HZ2
|
{'Adipose Tissue': 9.363179401993357, 'Adrenal Gland': 6.2882984496124035, 'Bladder': 9.04309523809524, 'Blood': 4.581179332615716, 'Blood Vessel': 12.141896629213484, 'Brain': 3.6537502271006814, 'Breast': 8.987206971677558, 'Cervix Uteri': 11.423473684210526, 'Colon': 7.732209242618741, 'Esophagus': 7.91996124567474, 'Fallopian Tube': 11.163666666666666, 'Heart': 4.6233783972125435, 'Kidney': 4.875640449438203, 'Liver': 3.2195849557522127, 'Lung': 13.951828719723183, 'Muscle': 4.899508094645081, 'Nerve': 11.194544426494346, 'Ovary': 11.8934, 'Pancreas': 3.0836737804878047, 'Pituitary': 6.5534946996466426, 'Prostate': 7.792232653061224, 'Salivary Gland': 7.184561728395061, 'Skin': 9.094258153676064, 'Small Intestine': 8.007561497326202, 'Spleen': 9.109311203319502, 'Stomach': 5.8756295264623954, 'Testis': 10.41815512465374, 'Thyroid': 11.371986217457886, 'Uterus': 13.088964788732394, 'Vagina': 10.93697435897436}
|
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[1.0, 0.9, 0.93, 0.88, 0.79, 0.86, 0.85, 0.86, 0.84, 0.88, 0.83, 0.91, 0.98, 0.88, 0.94, 0.92, 0.91, 0.98, 0.94, 0.97, 0.94, 0.99, 0.96, 0.93, 0.96, 0.97, 0.99, 1.0, 0.98, 1.0, 0.99, 0.98, 0.98, 0.97, 0.97, 1.0, 1.0, 1.0, 0.98, 0.94, 0.97, 0.96, 0.95, 0.94, 0.97, 0.8, 0.81, 0.67, 0.9, 0.85, 0.83, 0.7, 0.71, 0.41, 0.07, 0.17, 0.8, 0.23, 0.56, 0.1, 0.34, 0.91, 0.84, 0.28, 0.53, 0.73, 0.59, 0.09, 0.39, 0.01, 0.47, 0.38, 0.19, 0.62, 0.25, 0.01, 0.02, 0.28, 0.56, 0.03, 0.05, 0.35, 0.05, 0.6, 0.37, 0.44, 0.27, 0.34, 0.0, 0.01, 0.44, 0.19, 0.04, 0.0, 0.18, 0.48, 0.19, 0.03, 0.7, 0.71, 0.61, 0.38, 0.55, 0.44, 0.0, 0.42, 0.46, 0.38, 0.6, 0.61, 0.77, 0.01, 0.41, 0.39, 0.83, 0.33, 0.15, 0.59, 0.66, 0.09, 0.6, 0.66, 0.02, 0.46, 0.68, 0.41, 0.0, 0.23, 0.39, 0.25, 0.39, 0.0, 0.33, 0.09, 0.54, 0.22, 0.8, 0.59, 0.08, 0.86, 0.59, 0.54, 0.14, 0.33, 0.06, 0.52, 0.56, 0.07, 0.78, 0.61, 0.21, 0.4, 0.7, 0.63, 0.03, 0.47, 0.33, 0.2, 0.68, 0.43, 0.6, 0.0, 0.68, 0.32, 0.25, 0.66, 0.65, 0.63, 0.2, 0.28, 0.3, 0.47, 0.46, 0.04, 0.64, 0.49, 0.08, 0.27, 0.77, 0.76, 0.59, 0.0, 0.38, 0.4, 0.17, 0.59, 0.21, 0.62, 0.04, 0.82, 0.45, 0.3, 0.71, 0.36, 0.69, 0.14, 0.04, 0.44, 0.53, 0.42, 0.19, 0.7, 0.62, 0.25, 0.36, 0.61, 0.69, 0.0, 0.42, 0.46, 0.08, 0.66, 0.2, 0.69, 0.01, 0.79, 0.45, 0.27, 0.67, 0.43, 0.68, 0.2, 0.3, 0.38, 0.68, 0.5, 0.1, 0.56, 0.58, 0.09, 0.33, 0.73, 0.7, 0.67, 0.0, 0.42, 0.25, 0.04, 0.59, 0.13, 0.62, 0.02, 0.6, 0.18, 0.38, 0.94, 0.43, 0.39, 0.07, 0.83, 0.58, 0.74, 0.13, 0.37, 0.27, 0.6, 0.38, 0.16, 0.64, 0.5, 0.12, 0.3, 0.78, 0.72, 0.35, 0.44, 0.66, 0.34, 0.01, 0.49, 0.56, 0.24, 0.33, 0.5, 0.65, 0.3, 0.54, 0.6, 0.68, 0.68, 0.58, 0.65, 0.63, 0.92, 0.9, 0.81, 0.6, 0.56, 0.76, 0.5, 0.46, 0.5, 0.53, 0.52, 0.64, 0.6, 0.55, 0.45, 0.53, 0.69, 0.64, 0.5, 0.52, 0.38, 0.54, 0.66, 0.66, 0.65, 0.54, 0.39, 0.66, 0.56, 0.61, 0.66, 0.46, 0.63, 0.4, 0.45, 0.48, 0.64, 0.6, 0.45, 0.62, 0.54, 0.73, 0.64, 0.49, 0.55, 0.49, 0.59, 0.59, 0.54, 0.43, 0.54, 0.59, 0.39, 0.53, 0.57, 0.67, 0.58, 0.51, 0.48, 0.33, 0.55, 0.63, 0.06, 0.14, 0.7, 0.16, 0.62, 0.02, 0.45, 0.17, 0.51, 0.07, 0.77, 0.05, 0.54, 0.57, 0.0, 0.35, 0.63, 0.2, 0.23, 0.6, 0.27, 0.03, 0.68, 0.47, 0.36, 0.51, 0.79, 0.05, 0.54, 0.18, 0.38, 0.1, 0.63, 0.22, 0.0, 0.01, 0.12, 0.13, 0.68, 0.56, 0.04, 0.03, 0.15, 0.01, 0.01, 0.0, 0.25, 0.0, 0.27, 0.0, 0.12, 0.24, 0.37, 0.71, 0.24, 0.9, 0.92, 0.15, 0.31, 0.28, 0.29, 0.01, 0.0, 0.02, 0.13, 0.04, 0.02, 0.03, 0.18, 0.41, 0.21, 0.75, 0.16, 0.04, 0.76, 0.83, 0.1, 0.57, 0.27, 0.24, 0.0, 0.48, 0.03, 0.23, 0.01, 0.29, 0.0, 0.04, 0.0, 0.16, 0.02, 0.16, 0.2, 0.84, 0.46, 0.98, 0.82, 0.59, 0.56, 0.4, 0.3, 0.56, 0.38, 0.49, 0.07, 0.44, 0.13, 0.47, 0.41, 0.82, 0.34, 0.63, 0.1, 0.02, 0.37, 0.57, 0.07, 0.84, 0.55, 0.62, 0.48, 0.11, 0.68, 0.58, 0.33, 0.22, 0.5, 0.25, 0.46, 0.52, 0.03, 0.01, 0.39, 0.12, 0.48, 0.16, 0.09, 0.72, 0.77, 0.43, 0.36, 0.05, 0.32, 0.45, 0.92, 0.4, 0.23, 0.0, 0.18, 0.0, 0.19, 0.0, 0.29, 0.09, 0.51, 0.29, 0.56, 0.53, 0.78, 0.71, 0.77, 0.76, 0.81, 0.89, 0.91, 0.89, 0.7, 0.87, 0.9, 0.81, 0.92, 0.92, 0.92, 0.95, 0.99, 0.97, 0.99]
| null | null | null | null |
IKBKG, IL17RA, TRAF6, IL17RC, IL17RB, CHUK, IKBKB
|
TRAF6
|
63
| null |
UBE2V1, UBE2N
| null | null | 53.377143
| 0.735505
| 85.06523
| 0.467069
| 1,478
|
O43791
|
H7C3H4
| null |
degron_data
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
SETD2
|
XRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTRNQPE
|
Homo sapiens
|
Nucleus
|
Not found
|
{}
| null |
{'Adipose Tissue': 24.89976245847176, 'Adrenal Gland': 16.689887596899226, 'Bladder': 27.96761904761905, 'Blood': 15.677047362755651, 'Blood Vessel': 30.275805243445692, 'Brain': 14.591847804693414, 'Breast': 26.499324618736384, 'Cervix Uteri': 35.986315789473686, 'Colon': 26.985586649550708, 'Esophagus': 23.528862283737023, 'Fallopian Tube': 32.63444444444444, 'Heart': 8.182119744483158, 'Kidney': 13.544696629213483, 'Liver': 9.264845132743362, 'Lung': 28.56003460207613, 'Muscle': 18.875367372353672, 'Nerve': 32.93126009693054, 'Ovary': 37.002611111111115, 'Pancreas': 9.681512195121952, 'Pituitary': 23.001544169611307, 'Prostate': 26.552285714285716, 'Salivary Gland': 21.08493827160494, 'Skin': 29.357320619126583, 'Small Intestine': 26.1344385026738, 'Spleen': 24.086564315352696, 'Stomach': 18.598504178272982, 'Testis': 36.12362880886426, 'Thyroid': 37.057539050535986, 'Uterus': 38.282042253521126, 'Vagina': 28.946217948717948}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
| null | null |
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| null | null | 50
|
O43791
|
O00330
|
22199232
|
UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
PDHX
|
MAASWRLGCDPRLLRYLVGFPGRRSVGLVKGALGWSVSRGANWRWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKDDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENPIRLA
|
Homo sapiens
|
Mitochondrion matrix
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '14.1', 'Basal respiratory cells': '25.7', 'Club cells': '20.8', 'Ionocytes': '28.0', 'Mucus glandular cells': '12.5', 'Serous glandular cells': '9.7', 'Gastric mucus-secreting cells': '17.7', 'Proximal enterocytes': '12.3', 'Paneth cells': '16.0', 'Distal enterocytes': '20.7', 'Intestinal goblet cells': '22.7', 'Exocrine glandular cells': '-0.487', 'Basal prostatic cells': '20.0', 'Prostatic glandular cells': '15.4', 'Breast glandular cells': '-0.076', 'Breast myoepithelial cells': '-0.129', 'Glandular and luminal cells': '16.2', 'Secretory cells': '13.8', 'Basal keratinocytes': '23.0', 'Suprabasal keratinocytes': '21.4', 'Basal squamous epithelial cells': '16.8', 'Squamous epithelial cells': '17.4', 'Alveolar cells type 1': '0.063', 'Alveolar cells type 2': '0.287', 'Salivary duct cells': '17.2', 'Ductal cells': '0.478', 'Hepatocytes': '0.440', 'Cholangiocytes': '19.1', 'Proximal tubular cells': '0.220', 'Distal tubular cells': '46.1', 'Collecting duct cells': '3.9', 'Mesothelial cells': '-0.095', 'Sertoli cells': '0.398', 'Granulosa cells': '14.6', 'Enteroendocrine cells': '23.3', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '0.243', 'Excitatory neurons': '82.6', 'Inhibitory neurons': '77.0', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '28.7', 'Bipolar cells': '22.4', 'Horizontal cells': '23.3', 'Astrocytes': '32.5', 'Oligodendrocyte precursor cells': '37.7', 'Oligodendrocytes': '49.7', 'Microglial cells': '23.3', 'Muller glia cells': '17.3', 'Schwann cells': '-0.002', 'Spermatogonia': '0.337', 'Spermatocytes': '0.394', 'Early spermatids': '0.279', 'Late spermatids': '-0.241', 'Oocytes': '39.7', 'Cytotrophoblasts': '62.3', 'Syncytiotrophoblasts': '81.7', 'Extravillous trophoblasts': '35.6', 'Endothelial cells': '11.5', 'Lymphatic endothelial cells': '15.3', 'Cardiomyocytes': '0.755', 'Skeletal myocytes': '0.301', 'Smooth muscle cells': '14.5', 'Adipocytes': '8.5', 'Melanocytes': '0.121', 'Fibroblasts': '15.7', 'Peritubular cells': '0.198', 'Endometrial stromal cells': '10.8', 'Ovarian stromal cells': '15.3', 'Undifferentiated cells': '23.7', 'T-cells': '11.4', 'B-cells': '13.6', 'Plasma cells': '16.0', 'Nk-cells': '10.1', 'Granulocytes': '8.2', 'Monocytes': '9.8', 'Macrophages': '13.1', 'Hofbauer cells': '22.4', 'Kupffer cells': '17.2', 'Dendritic cells': '6.0', 'Langerhans cells': '0.182', 'Erythroid cells': '-0.046', 'Adipocytes (Subcutaneous)': '0.694', 'Adipocytes (Visceral)': '0.718', 'Breast glandular cells (progenitors)': '-0.071', 'Adipocytes (Breast)': '0.408', 'Colon enterocytes': '-0.155', 'Colon enteroendocrine cells': '0.108', 'Enteric glia cells': '-0.153', 'Mitotic cells (Colon)': '-0.038', 'Mitotic cells (Heart)': '0.397', 'Podocytes': '0.054', 'Ascending Loop of Henle cells': '0.413', 'Intercalated cells': '0.115', 'Cholangiocyte': '0.270', 'NK-cells (Liver)': '-0.350', 'Respiratory ciliated cells': '-0.066', 'Mitotic cells (Lung)': '0.201', 'NK-cells (Lung)': '-0.214', 'B-cells (Lung)': '-0.283', 'Alpha cells': '0.371', 'Beta cells': '0.266', 'Prostate glandular cells': '-0.004', 'Prostate basal glandular cells': '0.129', 'Urothelial cells': '-0.006', 'Keratinocyte (other)': '0.210', 'Keratinocyte (granular)': '-0.255', 'Hair cortex cells': '-0.006', 'Inner root sheath cells': '0.034', 'Outer root sheath cells': '0.259', 'Sebaceous gland cells': '0.223', 'Eccrine sweat gland cells': '0.107', 'Adipocytes (Skin)': '-0.091', 'Mitotic cells (Skin)': '0.387', 'Parietal cells': '0.486', 'Chief cells': '0.164', 'Gastric mucous cells': '0.303', 'Gastric enteroendocrine cells': '0.159', 'Mitotic cells (Stomach)': '0.156', 'Parafollicular cells': '0.133', 'Thyroid glandular cells': '0.435', 'Mitotic cells (Thyroid)': '-0.004', 'Adrenal cortex cells': '0.523', 'Adrenal medulla cells': '0.015', 'Mitotic cells (Adrenal gland)': '0.349', 'Minor salivary glandular cells': '0.236', 'Minor salivary gland ductal cells': '0.115', 'Minor salivary gland basal cells': '0.263', 'Mitotic cells (Minor salivary gland)': '0.312', 'Adipocytes (Minor salivary gland)': '0.171', 'Somatotropes': '0.450', 'Lactotropes': '0.215', 'Gonadotropes': '0.193', 'Corticotropes': '-0.109', 'Thyrotropes': '0.067', 'Undifferentiated cells (Pituitary gland)': '-0.176', 'Mitotic cells (Spleen)': '-0.106', 'Platelets': '-0.208', 'Erythrocytes': '-0.100', 'Hematopoietic stem cells': '-0.271', 'B-cells (Spleen)': '0.241', 'NK-cells (Spleen)': '0.229', 'Amygdala excitatory': '100.7', 'Cerebellar inhibitory': '96.7', 'Cge interneuron': '101.2', 'Deep-layer corticothalamic and 6b': '103.8', 'Deep-layer intratelencephalic': '91.5', 'Deep-layer near-projecting': '95.9', 'Eccentric medium spiny neuron': '99.2', 'Hippocampal ca1-3': '109.5', 'Hippocampal ca4': '123.8', 'Hippocampal dentate gyrus': '152.2', 'Lamp5-lhx6 and chandelier': '109.8', 'Lower rhombic lip': '194.3', 'Mammillary body': '127.5', 'Medium spiny neuron': '119.6', 'Mge interneuron': '109.2', 'Midbrain-derived inhibitory': '123.6', 'Miscellaneous': '92.4', 'Splatter': '109.2', 'Thalamic excitatory': '123.3', 'Upper rhombic lip': '95.5', 'Upper-layer intratelencephalic': '96.5', 'Astrocyte': '73.8', 'Bergmann glia': '48.8', 'Central nervous system macrophage': '71.4', 'Choroid plexus epithelial cell': '120.2', 'Committed oligodendrocyte precursor': '70.3', 'Ependymal cell': '65.4', 'Oligodendrocyte': '87.7', 'Oligodendrocyte precursor cell': '74.8', 'Endothelial cell': '63.2', 'Pericyte': '78.7', 'Vascular associated smooth muscle cell': '69.8', 'Fibroblast': '83.0', 'Leukocyte': '50.9', 'Basophil': '26.4', 'Eosinophil': '17.6', 'Neutrophil': '5.3', 'Classical monocyte': '17.1', 'Non-classical monocyte': '22.0', 'Intermediate monocyte': '48.3', 'T-reg': '33.4', 'GdT-cell': '15.5', 'MAIT T-cell': '28.5', 'Memory CD4 T-cell': '14.4', 'Naive CD4 T-cell': '36.1', 'Memory CD8 T-cell': '12.8', 'Naive CD8 T-cell': '30.7', 'Memory B-cell': '18.9', 'Naive B-cell': '28.8', 'Plasmacytoid DC': '24.0', 'Myeloid DC': '52.5', 'NK-cell': '25.2', 'Total PBMC': '31.1', 'Vd2 gdTCR': '26.8', 'Memory CD4 T-cell Th1\\/Th17': '30.3', 'Memory CD4 T-cell Th17': '26.0', 'Memory CD4 T-cell Th2': '28.7', 'Non-Vd2 gdTCR': '35.0', 'Memory CD4 T-cell Th1': '26.9', 'Memory CD4 T-cell TFH': '27.4', 'Terminal effector memory CD4 T-cell': '40.3', 'Central memory CD8 T-cell': '30.5', 'Effector memory CD8 T-cell': '32.9', 'Terminal effector memory CD8 T-cell': '31.2', 'Non-switched memory B-cell': '24.0', 'Plasmablast': '53.6', 'Switched memory B-cell': '30.4', 'Exhausted memory B-cell': '33.0', 'Progenitor cell': '36.8', 'Memory T-reg': '22.9', 'Naive CD4 T-cell activated': '18.6', 'Naive CD8 T-cell activated': '18.3', 'Naive T-reg': '38.2'}
|
1ZY8, 2DNC, 2F5Z, 2F60, 6H60
|
{'Adipose Tissue': 21.49300332225914, 'Adrenal Gland': 24.177279069767444, 'Bladder': 23.49904761904762, 'Blood': 7.611011517761034, 'Blood Vessel': 20.117165543071163, 'Brain': 19.426400832702495, 'Breast': 22.225359477124183, 'Cervix Uteri': 19.48315789473684, 'Colon': 18.88641591784339, 'Esophagus': 22.029272664359866, 'Fallopian Tube': 17.573333333333334, 'Heart': 29.02667804878049, 'Kidney': 12.82467415730337, 'Liver': 14.590013274336282, 'Lung': 17.237245674740485, 'Muscle': 54.08831880448319, 'Nerve': 18.92226171243942, 'Ovary': 17.68412222222222, 'Pancreas': 7.0352804878048785, 'Pituitary': 24.011766784452295, 'Prostate': 20.28935918367347, 'Salivary Gland': 18.151759259259254, 'Skin': 19.68787451630735, 'Small Intestine': 14.563470588235296, 'Spleen': 11.802016597510374, 'Stomach': 22.857791086350975, 'Testis': 35.077867036011085, 'Thyroid': 18.137087289433385, 'Uterus': 21.215352112676054, 'Vagina': 18.692179487179487}
|
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|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[39.19, 38.99, 38.97, 35.4, 37.3, 41.25, 37.05, 45.91, 35.71, 39.13, 38.18, 40.68, 40.52, 39.11, 33.43, 38.12, 38.71, 40.68, 36.13, 38.27, 38.64, 45.89, 36.86, 37.31, 32.63, 38.76, 35.68, 36.75, 36.92, 37.64, 34.17, 38.78, 38.92, 37.67, 31.76, 37.32, 36.86, 34.67, 36.54, 34.82, 38.5, 34.29, 35.82, 40.03, 31.89, 38.4, 34.9, 40.34, 37.5, 30.82, 33.0, 36.62, 40.96, 55.71, 72.64, 80.75, 85.62, 89.09, 88.84, 90.46, 90.53, 87.29, 88.07, 84.39, 81.17, 76.3, 78.48, 82.51, 82.84, 86.7, 84.97, 88.14, 89.86, 88.16, 90.68, 91.12, 88.76, 88.66, 87.46, 88.43, 83.8, 86.68, 86.35, 88.2, 86.95, 88.76, 87.73, 89.9, 90.64, 90.5, 89.89, 91.21, 89.95, 87.14, 85.85, 79.12, 78.47, 84.7, 88.55, 90.45, 90.12, 90.65, 91.63, 89.41, 87.62, 87.33, 87.75, 87.55, 86.49, 87.52, 84.38, 84.06, 87.63, 85.18, 84.86, 84.79, 86.3, 82.69, 82.42, 82.6, 81.91, 86.19, 87.93, 88.02, 87.18, 87.38, 88.81, 89.35, 88.39, 87.43, 87.95, 85.1, 80.32, 70.86, 64.61, 65.38, 66.18, 68.62, 61.59, 53.73, 59.66, 54.95, 56.93, 54.0, 48.5, 44.92, 47.0, 46.73, 48.87, 51.85, 48.75, 43.37, 44.3, 39.57, 37.36, 41.69, 40.73, 43.09, 48.41, 44.58, 43.77, 53.29, 44.0, 47.62, 42.41, 39.76, 41.65, 48.7, 48.01, 38.75, 42.47, 37.87, 38.95, 36.19, 38.31, 40.19, 37.88, 43.32, 43.8, 54.37, 64.07, 73.37, 82.47, 88.48, 88.27, 89.92, 90.0, 91.55, 90.98, 91.93, 91.06, 91.84, 90.04, 91.46, 89.98, 87.24, 86.08, 86.76, 82.17, 84.83, 82.28, 80.98, 83.49, 85.33, 85.67, 82.38, 77.01, 75.16, 81.21, 85.61, 90.32, 90.89, 91.78, 90.65, 91.22, 90.12, 90.27, 90.32, 88.13, 89.33, 87.72, 85.16, 83.08, 80.81, 78.11, 73.84, 65.22, 61.59, 52.45, 48.8, 50.45, 37.62, 45.17, 40.85, 46.65, 43.52, 46.07, 35.71, 45.94, 42.21, 46.55, 44.16, 49.22, 56.91, 56.72, 50.86, 48.58, 48.98, 45.69, 44.77, 41.28, 57.82, 49.02, 54.0, 58.01, 60.28, 57.72, 50.19, 62.76, 65.4, 61.47, 56.55, 61.19, 56.08, 57.93, 56.51, 59.45, 53.35, 57.29, 54.57, 59.13, 54.3, 66.76, 77.08, 79.83, 81.28, 82.5, 86.46, 87.13, 85.12, 86.63, 86.68, 84.76, 87.78, 89.41, 88.76, 88.93, 91.65, 92.67, 91.28, 92.95, 94.89, 92.77, 93.79, 94.43, 94.78, 92.39, 93.29, 94.07, 95.04, 95.6, 96.65, 96.22, 97.11, 95.98, 95.55, 94.59, 93.95, 92.63, 91.29, 91.7, 93.48, 92.41, 92.68, 92.68, 92.25, 92.55, 92.21, 90.99, 90.99, 91.51, 89.95, 88.35, 88.07, 90.07, 91.89, 92.78, 92.93, 94.2, 94.83, 94.89, 95.58, 96.24, 95.79, 95.93, 96.16, 95.78, 95.16, 95.73, 95.42, 93.94, 92.79, 93.55, 92.99, 92.59, 93.92, 94.74, 93.49, 92.29, 88.94, 81.88, 80.7, 81.12, 84.12, 89.48, 91.18, 91.62, 91.91, 89.71, 92.72, 94.94, 95.62, 96.63, 96.18, 96.02, 94.62, 93.17, 90.5, 88.93, 85.42, 81.35, 84.94, 87.55, 91.52, 93.93, 95.46, 96.34, 96.2, 94.47, 93.39, 93.72, 91.2, 92.5, 93.37, 92.72, 92.99, 92.75, 94.22, 95.8, 94.41, 95.27, 95.18, 95.19, 94.27, 95.21, 95.22, 92.84, 94.34, 94.84, 93.27, 92.06, 93.12, 88.83, 91.9, 91.27, 93.03, 91.05, 92.05, 92.95, 91.67, 89.96, 88.27, 89.99, 92.71, 95.61, 96.09, 96.96, 96.36, 95.06, 93.3, 89.81, 89.91, 91.65, 92.39, 94.78, 93.47, 95.55, 96.97, 96.6, 94.84, 95.14, 94.76, 91.32, 89.09, 90.53, 93.59, 93.92, 95.67, 96.71, 97.52, 97.41, 97.28, 96.26, 94.84, 92.44, 92.23, 91.94, 91.9, 91.23, 86.52, 87.61, 81.8, 82.39, 77.32, 77.8, 78.01, 78.17, 82.33, 82.86, 85.72, 87.15, 85.23, 89.6, 90.33, 91.98, 94.38, 95.66, 96.64, 97.17, 97.57, 96.9, 96.81, 95.61, 95.15, 93.35, 92.05, 92.57, 93.79, 92.5, 92.46, 94.7, 95.1, 95.3, 95.51, 96.57, 96.99, 96.85, 96.25, 95.71, 96.32, 95.92, 95.28, 94.6, 93.9, 93.66, 92.51, 87.7, 89.66, 87.28, 84.33, 70.38]
|
[1.0, 1.0, 0.97, 1.0, 0.98, 1.0, 0.91, 0.99, 0.85, 0.98, 0.96, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.9, 0.95, 0.87, 0.9, 0.92, 0.87, 0.92, 0.92, 0.9, 0.91, 0.46, 0.91, 0.27, 0.26, 0.52, 0.11, 0.52, 0.04, 0.33, 0.68, 0.31, 0.11, 0.97, 0.59, 0.07, 0.73, 0.46, 0.0, 0.16, 0.02, 0.44, 0.56, 0.11, 0.39, 0.13, 0.76, 0.48, 0.38, 0.38, 0.6, 0.04, 0.55, 0.52, 0.62, 0.34, 0.35, 0.01, 0.0, 0.32, 0.0, 0.46, 0.12, 0.56, 0.8, 0.51, 0.56, 0.34, 0.47, 0.1, 0.59, 0.08, 0.82, 0.46, 0.6, 0.04, 0.18, 0.0, 0.05, 0.37, 0.2, 0.35, 0.19, 0.81, 0.68, 0.48, 0.25, 0.62, 0.45, 0.08, 0.7, 0.36, 0.51, 0.33, 0.26, 0.0, 0.0, 0.0, 0.02, 0.04, 0.68, 0.79, 0.91, 0.35, 0.71, 0.44, 0.95, 0.81, 0.18, 0.87, 0.42, 0.37, 0.91, 0.93, 0.76, 0.87, 0.92, 0.76, 0.88, 0.86, 0.82, 0.83, 0.9, 0.88, 0.87, 0.92, 0.9, 0.97, 0.89, 0.96, 0.93, 0.99, 0.92, 0.99, 0.74, 0.99, 0.85, 0.97, 1.0, 0.99, 1.0, 0.99, 0.69, 0.84, 0.98, 0.98, 0.78, 0.53, 0.78, 0.22, 0.81, 0.21, 0.24, 0.77, 0.44, 0.0, 0.51, 0.47, 0.16, 0.05, 0.66, 0.76, 0.42, 0.6, 0.12, 0.39, 0.05, 0.58, 0.4, 0.21, 0.78, 0.26, 0.64, 0.15, 0.81, 0.79, 0.38, 0.35, 0.0, 0.27, 0.55, 0.68, 0.03, 0.0, 0.42, 0.49, 0.02, 0.11, 0.59, 0.36, 0.34, 0.77, 0.71, 0.75, 0.82, 0.23, 0.85, 0.67, 0.65, 0.93, 0.9, 0.92, 0.94, 0.95, 0.96, 0.97, 0.99, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.86, 0.86, 0.85, 0.91, 0.84, 0.92, 0.79, 0.92, 0.85, 0.8, 0.74, 0.81, 0.24, 0.68, 0.88, 0.93, 0.78, 0.92, 0.55, 0.58, 0.98, 0.92, 0.5, 0.51, 0.67, 0.46, 0.88, 0.74, 0.51, 0.46, 0.43, 0.52, 0.64, 0.36, 0.47, 0.34, 0.46, 0.68, 0.62, 0.43, 0.61, 0.51, 0.01, 0.47, 0.76, 0.56, 0.11, 0.43, 0.16, 0.13, 0.5, 0.19, 0.49, 0.23, 0.39, 0.01, 0.16, 0.0, 0.33, 0.33, 0.0, 0.27, 0.64, 0.32, 0.35, 0.63, 0.48, 0.24, 0.55, 0.74, 0.7, 0.73, 0.25, 0.81, 0.07, 0.39, 0.08, 0.17, 0.03, 0.01, 0.02, 0.0, 0.04, 0.0, 0.0, 0.0, 0.14, 0.0, 0.01, 0.69, 0.53, 0.17, 0.43, 0.54, 0.02, 0.02, 0.07, 0.16, 0.3, 0.47, 0.64, 0.82, 0.13, 0.62, 0.43, 0.58, 0.2, 0.93, 0.45, 0.1, 0.13, 0.0, 0.03, 0.11, 0.29, 0.07, 0.67, 0.2, 0.97, 0.71, 0.34, 0.61, 0.3, 0.2, 0.03, 0.09, 0.02, 0.57, 0.47, 0.0, 0.2, 0.82, 0.29, 0.42, 0.2, 0.52, 0.54, 0.0, 0.11, 0.59, 0.25, 0.16, 0.73, 0.48, 0.14, 0.15, 0.64, 0.38, 0.02, 0.71, 0.54, 0.64, 0.71, 0.15, 0.52, 0.46, 0.63, 0.16, 0.4, 0.66, 0.56, 0.17, 0.02, 0.0, 0.03, 0.03, 0.16, 0.36, 0.25, 0.2, 0.93, 0.67, 0.43, 0.33, 0.37, 0.6, 0.16, 0.63, 0.16, 0.32, 0.0, 0.34, 0.51, 0.47, 0.05, 0.01, 0.01, 0.07, 0.0, 0.01, 0.02, 0.04, 0.37, 0.46, 0.28, 0.63, 0.34, 0.66, 0.56, 0.66, 0.14, 0.85, 0.37, 1.0, 0.82, 0.6, 0.53, 0.7, 0.51, 0.64, 0.36, 0.67, 0.33, 0.32, 0.18, 0.0, 0.05, 0.0, 0.01, 0.01, 0.01, 0.02, 0.01, 0.46, 0.41, 0.21, 0.0, 0.51, 0.63, 0.56, 0.18, 0.03, 0.58, 0.51, 0.0, 0.07, 0.73, 0.21, 0.0, 0.34, 0.25, 0.02, 0.0, 0.33, 0.48, 0.16, 0.87, 0.55, 0.02, 0.83]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 76.853673
| 0.513852
| 1,583
|
O43791
|
O15164
|
25278611
|
UbiNet, UbiBrowser, DegPred
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
TRIM24
|
MEVAVEKAVAAAAAASAAASGGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTCAVCHQNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFATQVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCETCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQNIINLGSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQVMAQRQQVQRRPAPVGLPNPRMQGPIQQPSISHQQPPPRLINFQNHSPKPNGPVLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQISSGQGTPSTTNSTSSTPSSPTITSAAGYDGKAFGSPMIDLSSPVGGSYNLPSLPDIDCSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNANYPRSILTSLLLNSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKRFPKPEFRNESEDNKFSDDSDDDFVQPRKKRLKSIEERQLLK
|
Homo sapiens
|
Nucleus, Cytoplasm, Mitochondrion
|
Low tissue specificity
|
{'Ciliated cells': '14.3', 'Basal respiratory cells': '14.1', 'Club cells': '19.6', 'Ionocytes': '12.9', 'Mucus glandular cells': '30.4', 'Serous glandular cells': '14.3', 'Gastric mucus-secreting cells': '23.0', 'Proximal enterocytes': '6.4', 'Paneth cells': '10.2', 'Distal enterocytes': '14.4', 'Intestinal goblet cells': '8.6', 'Exocrine glandular cells': '-0.529', 'Basal prostatic cells': '15.6', 'Prostatic glandular cells': '56.1', 'Breast glandular cells': '0.508', 'Breast myoepithelial cells': '0.424', 'Glandular and luminal cells': '25.8', 'Secretory cells': '17.3', 'Basal keratinocytes': '18.9', 'Suprabasal keratinocytes': '28.4', 'Basal squamous epithelial cells': '11.7', 'Squamous epithelial cells': '23.5', 'Alveolar cells type 1': '0.218', 'Alveolar cells type 2': '0.373', 'Salivary duct cells': '30.4', 'Ductal cells': '0.553', 'Hepatocytes': '0.453', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.093', 'Distal tubular cells': '6.1', 'Collecting duct cells': '7.8', 'Mesothelial cells': '0.149', 'Sertoli cells': '-0.308', 'Granulosa cells': '77.3', 'Enteroendocrine cells': '13.0', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '-0.332', 'Excitatory neurons': '26.9', 'Inhibitory neurons': '44.6', 'Cone photoreceptor cells': '20.4', 'Rod photoreceptor cells': '25.7', 'Bipolar cells': '13.6', 'Horizontal cells': '22.0', 'Astrocytes': '24.8', 'Oligodendrocyte precursor cells': '60.4', 'Oligodendrocytes': '62.5', 'Microglial cells': '20.6', 'Muller glia cells': '20.6', 'Schwann cells': '-0.106', 'Spermatogonia': '-0.077', 'Spermatocytes': '0.385', 'Early spermatids': '0.807', 'Late spermatids': '0.447', 'Oocytes': '17.6', 'Cytotrophoblasts': '29.1', 'Syncytiotrophoblasts': '22.9', 'Extravillous trophoblasts': '14.3', 'Endothelial cells': '20.3', 'Lymphatic endothelial cells': '33.9', 'Cardiomyocytes': '0.677', 'Skeletal myocytes': '-0.241', 'Smooth muscle cells': '13.5', 'Adipocytes': '27.8', 'Melanocytes': '0.189', 'Fibroblasts': '14.6', 'Peritubular cells': '-0.250', 'Endometrial stromal cells': '22.7', 'Ovarian stromal cells': '39.3', 'Undifferentiated cells': '21.7', 'T-cells': '16.7', 'B-cells': '9.4', 'Plasma cells': '18.3', 'Nk-cells': '16.1', 'Granulocytes': '56.4', 'Monocytes': '21.2', 'Macrophages': '15.3', 'Hofbauer cells': '10.3', 'Kupffer cells': '7.2', 'Dendritic cells': '11.7', 'Langerhans cells': '0.387', 'Erythroid cells': '-0.012', 'Adipocytes (Subcutaneous)': '-0.120', 'Adipocytes (Visceral)': '-0.158', 'Breast glandular cells (progenitors)': '0.487', 'Adipocytes (Breast)': '-0.378', 'Colon enterocytes': '0.003', 'Colon enteroendocrine cells': '0.159', 'Enteric glia cells': '-0.171', 'Mitotic cells (Colon)': '0.012', 'Mitotic cells (Heart)': '0.503', 'Podocytes': '-0.181', 'Ascending Loop of Henle cells': '0.552', 'Intercalated cells': '-0.032', 'Cholangiocyte': '0.019', 'NK-cells (Liver)': '0.054', 'Respiratory ciliated cells': '-0.049', 'Mitotic cells (Lung)': '0.100', 'NK-cells (Lung)': '-0.110', 'B-cells (Lung)': '-0.245', 'Alpha cells': '0.330', 'Beta cells': '0.211', 'Prostate glandular cells': '0.710', 'Prostate basal glandular cells': '0.405', 'Urothelial cells': '-0.028', 'Keratinocyte (other)': '0.301', 'Keratinocyte (granular)': '0.125', 'Hair cortex cells': '-0.111', 'Inner root sheath cells': '-0.075', 'Outer root sheath cells': '0.032', 'Sebaceous gland cells': '0.243', 'Eccrine sweat gland cells': '-0.033', 'Adipocytes (Skin)': '-0.068', 'Mitotic cells (Skin)': '0.374', 'Parietal cells': '0.264', 'Chief cells': '0.328', 'Gastric mucous cells': '0.417', 'Gastric enteroendocrine cells': '0.394', 'Mitotic cells (Stomach)': '0.441', 'Parafollicular cells': '0.058', 'Thyroid glandular cells': '0.421', 'Mitotic cells (Thyroid)': '-0.003', 'Adrenal cortex cells': '0.471', 'Adrenal medulla cells': '0.019', 'Mitotic cells (Adrenal gland)': '0.392', 'Minor salivary glandular cells': '0.083', 'Minor salivary gland ductal cells': '0.233', 'Minor salivary gland basal cells': '0.348', 'Mitotic cells (Minor salivary gland)': '0.221', 'Adipocytes (Minor salivary gland)': '-0.031', 'Somatotropes': '-0.005', 'Lactotropes': '-0.024', 'Gonadotropes': '0.121', 'Corticotropes': '-0.105', 'Thyrotropes': '-0.021', 'Undifferentiated cells (Pituitary gland)': '0.276', 'Mitotic cells (Spleen)': '-0.125', 'Platelets': '-0.063', 'Erythrocytes': '-0.037', 'Hematopoietic stem cells': '-0.221', 'B-cells (Spleen)': '0.260', 'NK-cells (Spleen)': '0.344', 'Amygdala excitatory': '81.9', 'Cerebellar inhibitory': '63.2', 'Cge interneuron': '99.1', 'Deep-layer corticothalamic and 6b': '56.0', 'Deep-layer intratelencephalic': '57.9', 'Deep-layer near-projecting': '78.3', 'Eccentric medium spiny neuron': '97.8', 'Hippocampal ca1-3': '75.4', 'Hippocampal ca4': '80.1', 'Hippocampal dentate gyrus': '73.2', 'Lamp5-lhx6 and chandelier': '75.3', 'Lower rhombic lip': '38.0', 'Mammillary body': '44.3', 'Medium spiny neuron': '89.6', 'Mge interneuron': '69.2', 'Midbrain-derived inhibitory': '44.3', 'Miscellaneous': '58.2', 'Splatter': '70.8', 'Thalamic excitatory': '58.8', 'Upper rhombic lip': '50.4', 'Upper-layer intratelencephalic': '62.2', 'Astrocyte': '56.3', 'Bergmann glia': '109.5', 'Central nervous system macrophage': '81.1', 'Choroid plexus epithelial cell': '56.2', 'Committed oligodendrocyte precursor': '85.5', 'Ependymal cell': '47.8', 'Oligodendrocyte': '114.6', 'Oligodendrocyte precursor cell': '124.1', 'Endothelial cell': '56.6', 'Pericyte': '50.7', 'Vascular associated smooth muscle cell': '35.3', 'Fibroblast': '46.8', 'Leukocyte': '88.2', 'Basophil': '14.1', 'Eosinophil': '1.0', 'Neutrophil': '17.2', 'Classical monocyte': '13.6', 'Non-classical monocyte': '16.1', 'Intermediate monocyte': '5.9', 'T-reg': '7.5', 'GdT-cell': '0.5', 'MAIT T-cell': '7.2', 'Memory CD4 T-cell': '0.4', 'Naive CD4 T-cell': '22.9', 'Memory CD8 T-cell': '0.3', 'Naive CD8 T-cell': '21.1', 'Memory B-cell': '0.2', 'Naive B-cell': '14.2', 'Plasmacytoid DC': '4.0', 'Myeloid DC': '7.7', 'NK-cell': '17.3', 'Total PBMC': '7.2', 'Vd2 gdTCR': '9.9', 'Memory CD4 T-cell Th1\\/Th17': '18.2', 'Memory CD4 T-cell Th17': '17.3', 'Memory CD4 T-cell Th2': '19.5', 'Non-Vd2 gdTCR': '8.7', 'Memory CD4 T-cell Th1': '16.7', 'Memory CD4 T-cell TFH': '15.3', 'Terminal effector memory CD4 T-cell': '7.1', 'Central memory CD8 T-cell': '8.0', 'Effector memory CD8 T-cell': '7.4', 'Terminal effector memory CD8 T-cell': '9.3', 'Non-switched memory B-cell': '5.6', 'Plasmablast': '6.0', 'Switched memory B-cell': '5.7', 'Exhausted memory B-cell': '5.8', 'Progenitor cell': '18.4', 'Memory T-reg': '14.3', 'Naive CD4 T-cell activated': '12.0', 'Naive CD8 T-cell activated': '13.6', 'Naive T-reg': '20.3'}
|
2YYN, 3O33, 3O34, 3O35, 3O36, 3O37, 4YAB, 4YAD, 4YAT, 4YAX, 4YBM, 4YBS, 4YBT, 4YC9, 4ZQL, 5H1T, 5H1U, 5H1V, 7B9X
|
{'Adipose Tissue': 6.43809634551495, 'Adrenal Gland': 20.766197674418606, 'Bladder': 8.203761904761905, 'Blood': 3.1808332615715824, 'Blood Vessel': 6.4433812734082405, 'Brain': 4.142842467827403, 'Breast': 7.030734204793029, 'Cervix Uteri': 7.568315789473684, 'Colon': 5.288907573812581, 'Esophagus': 5.922158477508651, 'Fallopian Tube': 6.911333333333333, 'Heart': 3.2039422764227643, 'Kidney': 3.133408988764045, 'Liver': 5.847588495575222, 'Lung': 7.681972318339101, 'Muscle': 5.716308841843088, 'Nerve': 7.753735056542811, 'Ovary': 17.218444444444444, 'Pancreas': 3.811330182926829, 'Pituitary': 4.254445229681979, 'Prostate': 8.333489795918368, 'Salivary Gland': 7.353283950617284, 'Skin': 6.604772249861802, 'Small Intestine': 5.457668449197861, 'Spleen': 5.285929460580913, 'Stomach': 6.994222841225627, 'Testis': 21.40381163434903, 'Thyroid': 6.497797856049004, 'Uterus': 7.279873239436619, 'Vagina': 6.762532051282051}
|
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0.42, 0.37, 0.51, 0.54, 0.14, 0.65, 0.72, 0.57, 0.38, 0.34, 0.32, 0.17, 0.38, 0.67, 0.53, 0.44, 0.52, 0.68, 0.18, 0.5, 0.7, 0.45, 0.12, 0.58, 0.62, 0.1, 0.69, 0.8, 0.44, 0.74, 0.41, 0.59, 0.77, 0.44, 0.36, 0.66, 0.87, 0.36, 0.57, 0.84, 0.66, 0.15, 0.31, 0.63, 0.57, 0.34, 0.61, 0.53, 0.15, 0.8, 0.82, 0.42, 0.89, 0.55, 0.66, 0.89, 0.74, 0.57, 0.64, 0.22, 0.84, 0.71, 0.81, 0.45, 0.69, 0.76, 0.8, 0.57, 0.54, 0.67, 0.67, 0.62, 0.62, 0.46, 0.66, 0.49, 0.59, 0.72, 0.76, 0.55, 0.87, 0.86, 0.8, 0.82, 0.82, 0.67, 0.79, 0.72, 0.92, 0.56, 0.88, 0.72, 0.76, 0.62, 0.67, 0.76, 0.94, 0.89, 0.93, 0.92, 0.98, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.87, 0.95, 0.65, 0.48, 0.54, 0.61, 0.59, 0.49, 0.67, 0.65, 0.61, 0.52, 0.56, 0.64, 0.62, 0.52, 0.54, 0.56, 0.4, 0.66, 0.77, 0.65, 0.72, 0.84, 0.85, 0.9, 0.97, 0.97, 0.98, 0.96, 0.94, 1.0, 0.96, 0.99, 0.98, 0.99, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.97, 0.97, 1.0, 0.98, 1.0, 1.0, 0.97, 1.0, 0.95, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.99, 0.94, 0.96, 1.0, 0.96, 0.98, 0.98, 0.95, 0.97, 0.87, 0.96, 0.96, 0.67, 0.55, 0.72, 0.71, 0.57, 0.56, 0.36, 0.58, 0.59, 0.23, 0.63, 0.46, 0.48, 0.5, 0.67, 0.71, 0.79, 0.8, 0.82, 0.78, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.91, 1.0, 0.96, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.85, 1.0, 0.97, 0.97, 0.99, 0.97, 0.99, 0.88, 1.0, 0.81, 1.0, 0.96, 1.0, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.91, 0.99, 0.93, 0.84, 1.0, 0.69, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 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0.36, 0.4, 0.32, 0.57, 0.76, 0.64, 0.9, 0.94, 0.92, 0.96, 0.96, 0.92, 0.79, 0.78, 0.76, 0.81, 0.64, 0.68, 0.61, 0.16, 0.51, 0.65, 0.42, 0.18, 0.25, 0.11, 0.18, 0.01, 0.03, 0.12, 0.0, 0.0, 0.0, 0.27, 0.0, 0.09, 0.25, 0.25, 0.89, 0.37, 0.01, 0.75, 0.6, 0.07, 0.18, 0.74, 0.55, 0.26, 0.58, 0.79, 0.8, 0.34, 0.8, 0.35, 0.07, 0.43, 0.56, 0.22, 0.05, 0.75, 0.63, 0.46, 0.09, 0.07, 0.02, 0.3, 0.29, 0.0, 0.1, 0.61, 0.29, 0.02, 0.39, 0.39, 0.66, 0.71, 0.21, 0.66, 0.02, 0.43, 0.54, 0.06, 0.38, 0.23, 0.0, 0.03, 0.34, 0.11, 0.01, 0.04, 0.18, 0.05, 0.06, 0.35, 0.09, 0.05, 0.59, 0.23, 0.23, 0.28, 0.41, 0.65, 0.84, 0.29, 0.83, 0.35, 0.08, 0.41, 0.1, 0.04, 0.52, 0.57, 0.02, 0.28, 0.63, 0.3, 0.0, 0.27, 0.6, 0.12, 0.03, 0.72, 0.64, 0.17, 0.06, 0.73, 0.99, 0.37, 0.93, 0.13, 0.78, 0.57, 0.37, 0.85, 0.65, 0.75, 0.78, 0.72, 0.88, 0.77, 0.98, 0.9, 0.99, 0.9, 1.0, 0.98, 1.0, 0.91, 1.0, 0.89, 0.85, 0.75, 0.28, 0.42, 0.36, 0.38, 0.58, 0.46, 0.54, 0.44, 0.62, 0.48, 0.54, 0.56, 0.57, 0.7, 0.69, 0.8, 0.83, 0.78]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 62.797781
| 0.665467
| 461
|
O43791
|
O60885
|
28805820:28805822, 28805820
|
UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
BRD4
|
MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF
|
Homo sapiens
|
Nucleus, Chromosome, Chromosome
|
Low tissue specificity
|
{'Ciliated cells': '61.6', 'Basal respiratory cells': '37.4', 'Club cells': '72.1', 'Ionocytes': '37.9', 'Mucus glandular cells': '147.9', 'Serous glandular cells': '63.0', 'Gastric mucus-secreting cells': '51.9', 'Proximal enterocytes': '42.7', 'Paneth cells': '43.3', 'Distal enterocytes': '73.5', 'Intestinal goblet cells': '62.3', 'Exocrine glandular cells': '-0.769', 'Basal prostatic cells': '93.4', 'Prostatic glandular cells': '62.6', 'Breast glandular cells': '0.549', 'Breast myoepithelial cells': '0.483', 'Glandular and luminal cells': '125.6', 'Secretory cells': '71.9', 'Basal keratinocytes': '113.4', 'Suprabasal keratinocytes': '141.4', 'Basal squamous epithelial cells': '82.4', 'Squamous epithelial cells': '83.2', 'Alveolar cells type 1': '0.180', 'Alveolar cells type 2': '-0.382', 'Salivary duct cells': '134.8', 'Ductal cells': '0.613', 'Hepatocytes': '0.073', 'Cholangiocytes': '55.3', 'Proximal tubular cells': '0.131', 'Distal tubular cells': '30.7', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.305', 'Sertoli cells': '0.482', 'Granulosa cells': '75.3', 'Enteroendocrine cells': '57.0', 'Pancreatic endocrine cells': '30.6', 'Leydig cells': '0.415', 'Excitatory neurons': '44.8', 'Inhibitory neurons': '42.3', 'Cone photoreceptor cells': '57.8', 'Rod photoreceptor cells': '84.8', 'Bipolar cells': '54.0', 'Horizontal cells': '68.6', 'Astrocytes': '25.4', 'Oligodendrocyte precursor cells': '26.9', 'Oligodendrocytes': '36.6', 'Microglial cells': '46.5', 'Muller glia cells': '34.9', 'Schwann cells': '0.092', 'Spermatogonia': '0.528', 'Spermatocytes': '0.383', 'Early spermatids': '-0.337', 'Late spermatids': '-0.401', 'Oocytes': '43.4', 'Cytotrophoblasts': '221.0', 'Syncytiotrophoblasts': '242.3', 'Extravillous trophoblasts': '73.1', 'Endothelial cells': '81.1', 'Lymphatic endothelial cells': '74.6', 'Cardiomyocytes': '0.504', 'Skeletal myocytes': '-0.320', 'Smooth muscle cells': '91.1', 'Adipocytes': '87.0', 'Melanocytes': '0.126', 'Fibroblasts': '74.1', 'Peritubular cells': '0.289', 'Endometrial stromal cells': '103.4', 'Ovarian stromal cells': '55.0', 'Undifferentiated cells': '54.9', 'T-cells': '89.7', 'B-cells': '104.1', 'Plasma cells': '75.1', 'Nk-cells': '91.6', 'Granulocytes': '85.3', 'Monocytes': '238.7', 'Macrophages': '105.4', 'Hofbauer cells': '55.3', 'Kupffer cells': '76.0', 'Dendritic cells': '254.4', 'Langerhans cells': '0.107', 'Erythroid cells': '0.002', 'Adipocytes (Subcutaneous)': '-0.366', 'Adipocytes (Visceral)': '-0.362', 'Breast glandular cells (progenitors)': '0.381', 'Adipocytes (Breast)': '-0.581', 'Colon enterocytes': '-0.167', 'Colon enteroendocrine cells': '0.180', 'Enteric glia cells': '0.044', 'Mitotic cells (Colon)': '-0.071', 'Mitotic cells (Heart)': '0.467', 'Podocytes': '-0.160', 'Ascending Loop of Henle cells': '0.376', 'Intercalated cells': '-0.125', 'Cholangiocyte': '0.209', 'NK-cells (Liver)': '-0.102', 'Respiratory ciliated cells': '0.006', 'Mitotic cells (Lung)': '-0.295', 'NK-cells (Lung)': '0.388', 'B-cells (Lung)': '0.217', 'Alpha cells': '0.374', 'Beta cells': '0.201', 'Prostate glandular cells': '-0.147', 'Prostate basal glandular cells': '0.263', 'Urothelial cells': '0.301', 'Keratinocyte (other)': '0.395', 'Keratinocyte (granular)': '0.165', 'Hair cortex cells': '-0.182', 'Inner root sheath cells': '-0.144', 'Outer root sheath cells': '-0.082', 'Sebaceous gland cells': '-0.181', 'Eccrine sweat gland cells': '-0.280', 'Adipocytes (Skin)': '-0.279', 'Mitotic cells (Skin)': '0.064', 'Parietal cells': '-0.626', 'Chief cells': '-0.561', 'Gastric mucous cells': '-0.338', 'Gastric enteroendocrine cells': '-0.379', 'Mitotic cells (Stomach)': '0.024', 'Parafollicular cells': '0.068', 'Thyroid glandular cells': '0.164', 'Mitotic cells (Thyroid)': '-0.066', 'Adrenal cortex cells': '0.241', 'Adrenal medulla cells': '0.003', 'Mitotic cells (Adrenal gland)': '0.098', 'Minor salivary glandular cells': '0.606', 'Minor salivary gland ductal cells': '-0.005', 'Minor salivary gland basal cells': '0.371', 'Mitotic cells (Minor salivary gland)': '0.455', 'Adipocytes (Minor salivary gland)': '0.152', 'Somatotropes': '-0.072', 'Lactotropes': '-0.192', 'Gonadotropes': '-0.056', 'Corticotropes': '-0.032', 'Thyrotropes': '-0.095', 'Undifferentiated cells (Pituitary gland)': '0.180', 'Mitotic cells (Spleen)': '-0.274', 'Platelets': '-0.148', 'Erythrocytes': '-0.146', 'Hematopoietic stem cells': '-0.309', 'B-cells (Spleen)': '0.489', 'NK-cells (Spleen)': '0.276', 'Amygdala excitatory': '109.4', 'Cerebellar inhibitory': '72.9', 'Cge interneuron': '81.5', 'Deep-layer corticothalamic and 6b': '93.8', 'Deep-layer intratelencephalic': '109.4', 'Deep-layer near-projecting': '89.9', 'Eccentric medium spiny neuron': '95.2', 'Hippocampal ca1-3': '89.4', 'Hippocampal ca4': '83.0', 'Hippocampal dentate gyrus': '81.6', 'Lamp5-lhx6 and chandelier': '82.6', 'Lower rhombic lip': '91.6', 'Mammillary body': '124.2', 'Medium spiny neuron': '91.6', 'Mge interneuron': '97.4', 'Midbrain-derived inhibitory': '78.7', 'Miscellaneous': '96.9', 'Splatter': '88.6', 'Thalamic excitatory': '97.2', 'Upper rhombic lip': '69.7', 'Upper-layer intratelencephalic': '97.7', 'Astrocyte': '76.7', 'Bergmann glia': '64.7', 'Central nervous system macrophage': '175.1', 'Choroid plexus epithelial cell': '89.0', 'Committed oligodendrocyte precursor': '79.3', 'Ependymal cell': '77.6', 'Oligodendrocyte': '77.7', 'Oligodendrocyte precursor cell': '71.4', 'Endothelial cell': '137.4', 'Pericyte': '161.8', 'Vascular associated smooth muscle cell': '138.9', 'Fibroblast': '107.9', 'Leukocyte': '163.3', 'Basophil': '16.7', 'Eosinophil': '2.2', 'Neutrophil': '40.9', 'Classical monocyte': '24.6', 'Non-classical monocyte': '26.9', 'Intermediate monocyte': '15.8', 'T-reg': '16.5', 'GdT-cell': '2.1', 'MAIT T-cell': '19.8', 'Memory CD4 T-cell': '1.8', 'Naive CD4 T-cell': '34.4', 'Memory CD8 T-cell': '1.8', 'Naive CD8 T-cell': '35.8', 'Memory B-cell': '3.7', 'Naive B-cell': '33.8', 'Plasmacytoid DC': '14.2', 'Myeloid DC': '20.1', 'NK-cell': '33.0', 'Total PBMC': '16.8', 'Vd2 gdTCR': '16.9', 'Memory CD4 T-cell Th1\\/Th17': '29.2', 'Memory CD4 T-cell Th17': '34.4', 'Memory CD4 T-cell Th2': '37.3', 'Non-Vd2 gdTCR': '18.1', 'Memory CD4 T-cell Th1': '40.1', 'Memory CD4 T-cell TFH': '50.8', 'Terminal effector memory CD4 T-cell': '17.9', 'Central memory CD8 T-cell': '16.3', 'Effector memory CD8 T-cell': '21.1', 'Terminal effector memory CD8 T-cell': '17.7', 'Non-switched memory B-cell': '22.3', 'Plasmablast': '9.6', 'Switched memory B-cell': '24.0', 'Exhausted memory B-cell': '21.5', 'Progenitor cell': '13.5', 'Memory T-reg': '50.7', 'Naive CD4 T-cell activated': '55.9', 'Naive CD8 T-cell activated': '53.2', 'Naive T-reg': '43.4'}
|
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{'Adipose Tissue': 26.91641196013289, 'Adrenal Gland': 20.29530620155039, 'Bladder': 30.30238095238095, 'Blood': 22.94751130247578, 'Blood Vessel': 36.65269662921348, 'Brain': 13.123299015897048, 'Breast': 28.25483660130719, 'Cervix Uteri': 37.86631578947369, 'Colon': 24.9476405648267, 'Esophagus': 25.32779861591696, 'Fallopian Tube': 33.68555555555556, 'Heart': 12.264243902439024, 'Kidney': 14.935651685393257, 'Liver': 13.100353982300884, 'Lung': 35.567093425605535, 'Muscle': 25.806145703611456, 'Nerve': 35.16255250403877, 'Ovary': 39.1645, 'Pancreas': 10.91909756097561, 'Pituitary': 25.262968197879857, 'Prostate': 30.457265306122448, 'Salivary Gland': 22.304376543209877, 'Skin': 32.53112769485904, 'Small Intestine': 27.358508021390374, 'Spleen': 31.777178423236514, 'Stomach': 18.96657660167131, 'Testis': 34.702936288088644, 'Thyroid': 33.420935681470134, 'Uterus': 40.48985915492958, 'Vagina': 33.21775641025641}
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|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.94, 1.0, 0.97, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 1.0, 0.99, 1.0, 1.0, 0.99, 0.94, 0.92, 0.93, 0.84, 0.91, 0.87, 0.62, 0.76, 0.85, 0.41, 0.5, 0.96, 0.81, 0.25, 0.44, 0.23, 0.46, 0.27, 0.87, 0.91, 0.42, 0.64, 0.5, 0.13, 0.16, 0.0, 0.23, 0.12, 0.02, 0.27, 0.14, 0.0, 0.27, 0.54, 0.35, 0.01, 0.03, 0.6, 0.32, 0.01, 0.32, 0.74, 0.31, 0.85, 0.4, 0.0, 0.73, 0.33, 0.07, 0.26, 0.66, 0.46, 0.26, 0.36, 0.07, 0.52, 0.83, 0.62, 0.79, 0.26, 0.57, 0.41, 0.07, 0.27, 0.57, 0.47, 0.02, 0.77, 0.64, 0.27, 0.13, 0.05, 0.0, 0.05, 0.03, 0.0, 0.34, 0.48, 0.09, 0.05, 0.5, 0.34, 0.17, 0.21, 0.03, 0.48, 0.34, 0.01, 0.66, 0.31, 0.0, 0.13, 0.63, 0.11, 0.0, 0.41, 0.22, 0.04, 0.0, 0.29, 0.06, 0.06, 0.3, 0.46, 0.23, 0.24, 0.74, 0.9, 0.9, 0.38, 0.68, 0.31, 0.06, 0.58, 0.13, 0.0, 0.49, 0.3, 0.0, 0.27, 0.73, 0.19, 0.01, 0.55, 0.59, 0.21, 0.23, 0.8, 0.46, 0.19, 0.43, 0.88, 0.76, 0.33, 0.49, 0.66, 0.3, 0.69, 0.39, 0.62, 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|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 55.011535
| 0.775866
| 251
|
O43791
|
O75367
|
nan, 15897469, E3NethUbiquitome, nan
|
degron_data, UbiNet, UbiBrowser, 31181401, degron_data
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
MACROH2A1
|
MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN
|
Homo sapiens
|
Nucleus, Chromosome
|
Low tissue specificity
|
{'Ciliated cells': '139.1', 'Basal respiratory cells': '187.8', 'Club cells': '151.8', 'Ionocytes': '133.6', 'Mucus glandular cells': '120.6', 'Serous glandular cells': '82.8', 'Gastric mucus-secreting cells': '107.9', 'Proximal enterocytes': '218.1', 'Paneth cells': '144.4', 'Distal enterocytes': '189.5', 'Intestinal goblet cells': '193.5', 'Exocrine glandular cells': '-0.635', 'Basal prostatic cells': '54.5', 'Prostatic glandular cells': '87.9', 'Breast glandular cells': '0.300', 'Breast myoepithelial cells': '0.144', 'Glandular and luminal cells': '145.7', 'Secretory cells': '90.1', 'Basal keratinocytes': '170.1', 'Suprabasal keratinocytes': '263.3', 'Basal squamous epithelial cells': '140.7', 'Squamous epithelial cells': '198.9', 'Alveolar cells type 1': '-0.169', 'Alveolar cells type 2': '0.464', 'Salivary duct cells': '119.3', 'Ductal cells': '0.716', 'Hepatocytes': '0.402', 'Cholangiocytes': '114.5', 'Proximal tubular cells': '0.118', 'Distal tubular cells': '58.4', 'Collecting duct cells': '77.8', 'Mesothelial cells': '0.067', 'Sertoli cells': '0.703', 'Granulosa cells': '71.0', 'Enteroendocrine cells': '163.8', 'Pancreatic endocrine cells': '186.8', 'Leydig cells': '0.743', 'Excitatory neurons': '51.1', 'Inhibitory neurons': '43.9', 'Cone photoreceptor cells': '192.0', 'Rod photoreceptor cells': '165.8', 'Bipolar cells': '141.6', 'Horizontal cells': '178.8', 'Astrocytes': '41.5', 'Oligodendrocyte precursor cells': '33.0', 'Oligodendrocytes': '47.8', 'Microglial cells': '59.0', 'Muller glia cells': '155.8', 'Schwann cells': '0.090', 'Spermatogonia': '0.527', 'Spermatocytes': '0.245', 'Early spermatids': '-0.518', 'Late spermatids': '-0.733', 'Oocytes': '99.3', 'Cytotrophoblasts': '158.1', 'Syncytiotrophoblasts': '203.5', 'Extravillous trophoblasts': '146.7', 'Endothelial cells': '93.3', 'Lymphatic endothelial cells': '76.4', 'Cardiomyocytes': '0.645', 'Skeletal myocytes': '-0.159', 'Smooth muscle cells': '86.2', 'Adipocytes': '116.5', 'Melanocytes': '0.336', 'Fibroblasts': '77.5', 'Peritubular cells': '0.561', 'Endometrial stromal cells': '132.8', 'Ovarian stromal cells': '73.1', 'Undifferentiated cells': '226.4', 'T-cells': '89.7', 'B-cells': '99.0', 'Plasma cells': '93.7', 'Nk-cells': '92.9', 'Granulocytes': '57.5', 'Monocytes': '564.6', 'Macrophages': '358.7', 'Hofbauer cells': '458.1', 'Kupffer cells': '417.4', 'Dendritic cells': '167.3', 'Langerhans cells': '0.337', 'Erythroid cells': '-0.043', 'Adipocytes (Subcutaneous)': '0.230', 'Adipocytes (Visceral)': '0.040', 'Breast glandular cells (progenitors)': '0.085', 'Adipocytes (Breast)': '-0.100', 'Colon enterocytes': '0.129', 'Colon enteroendocrine cells': '0.135', 'Enteric glia cells': '-0.170', 'Mitotic cells (Colon)': '0.270', 'Mitotic cells (Heart)': '0.547', 'Podocytes': '-0.096', 'Ascending Loop of Henle cells': '0.442', 'Intercalated cells': '-0.022', 'Cholangiocyte': '0.436', 'NK-cells (Liver)': '-0.342', 'Respiratory ciliated cells': '-0.089', 'Mitotic cells (Lung)': '0.333', 'NK-cells (Lung)': '-0.436', 'B-cells (Lung)': '-0.300', 'Alpha cells': '0.450', 'Beta cells': '0.296', 'Prostate glandular cells': '-0.092', 'Prostate basal glandular cells': '0.361', 'Urothelial cells': '0.400', 'Keratinocyte (other)': '0.469', 'Keratinocyte (granular)': '0.051', 'Hair cortex cells': '0.008', 'Inner root sheath cells': '0.143', 'Outer root sheath cells': '0.085', 'Sebaceous gland cells': '-0.021', 'Eccrine sweat gland cells': '-0.331', 'Adipocytes (Skin)': '-0.356', 'Mitotic cells (Skin)': '0.425', 'Parietal cells': '-0.487', 'Chief cells': '-0.533', 'Gastric mucous cells': '0.013', 'Gastric enteroendocrine cells': '-0.330', 'Mitotic cells (Stomach)': '0.406', 'Parafollicular cells': '0.084', 'Thyroid glandular cells': '0.451', 'Mitotic cells (Thyroid)': '0.009', 'Adrenal cortex cells': '0.417', 'Adrenal medulla cells': '0.107', 'Mitotic cells (Adrenal gland)': '0.373', 'Minor salivary glandular cells': '0.256', 'Minor salivary gland ductal cells': '-0.233', 'Minor salivary gland basal cells': '0.786', 'Mitotic cells (Minor salivary gland)': '0.788', 'Adipocytes (Minor salivary gland)': '0.184', 'Somatotropes': '0.208', 'Lactotropes': '0.275', 'Gonadotropes': '0.099', 'Corticotropes': '0.248', 'Thyrotropes': '0.346', 'Undifferentiated cells (Pituitary gland)': '-0.150', 'Mitotic cells (Spleen)': '-0.149', 'Platelets': '0.158', 'Erythrocytes': '-0.073', 'Hematopoietic stem cells': '0.148', 'B-cells (Spleen)': '-0.025', 'NK-cells (Spleen)': '0.107', 'Amygdala excitatory': '96.2', 'Cerebellar inhibitory': '76.6', 'Cge interneuron': '78.2', 'Deep-layer corticothalamic and 6b': '85.1', 'Deep-layer intratelencephalic': '92.2', 'Deep-layer near-projecting': '83.1', 'Eccentric medium spiny neuron': '107.1', 'Hippocampal ca1-3': '69.9', 'Hippocampal ca4': '68.1', 'Hippocampal dentate gyrus': '76.5', 'Lamp5-lhx6 and chandelier': '76.6', 'Lower rhombic lip': '64.0', 'Mammillary body': '85.6', 'Medium spiny neuron': '109.2', 'Mge interneuron': '68.0', 'Midbrain-derived inhibitory': '90.6', 'Miscellaneous': '79.3', 'Splatter': '78.3', 'Thalamic excitatory': '89.6', 'Upper rhombic lip': '100.1', 'Upper-layer intratelencephalic': '91.1', 'Astrocyte': '76.5', 'Bergmann glia': '50.5', 'Central nervous system macrophage': '264.6', 'Choroid plexus epithelial cell': '80.3', 'Committed oligodendrocyte precursor': '76.3', 'Ependymal cell': '76.1', 'Oligodendrocyte': '79.9', 'Oligodendrocyte precursor cell': '76.3', 'Endothelial cell': '88.2', 'Pericyte': '77.9', 'Vascular associated smooth muscle cell': '70.9', 'Fibroblast': '68.6', 'Leukocyte': '105.8', 'Basophil': '18.2', 'Eosinophil': '79.4', 'Neutrophil': '99.3', 'Classical monocyte': '136.7', 'Non-classical monocyte': '116.7', 'Intermediate monocyte': '124.7', 'T-reg': '44.5', 'GdT-cell': '37.5', 'MAIT T-cell': '32.2', 'Memory CD4 T-cell': '47.1', 'Naive CD4 T-cell': '45.0', 'Memory CD8 T-cell': '46.6', 'Naive CD8 T-cell': '38.4', 'Memory B-cell': '44.4', 'Naive B-cell': '31.4', 'Plasmacytoid DC': '207.6', 'Myeloid DC': '267.7', 'NK-cell': '39.4', 'Total PBMC': '102.2', 'Vd2 gdTCR': '35.8', 'Memory CD4 T-cell TFH': '45.0', 'Memory CD4 T-cell Th2': '44.6', 'Memory CD4 T-cell Th17': '41.8', 'Memory CD4 T-cell Th1\\/Th17': '38.1', 'Non-Vd2 gdTCR': '36.6', 'Memory CD4 T-cell Th1': '39.0', 'Terminal effector memory CD4 T-cell': '40.1', 'Central memory CD8 T-cell': '35.3', 'Effector memory CD8 T-cell': '45.9', 'Terminal effector memory CD8 T-cell': '35.7', 'Switched memory B-cell': '49.9', 'Plasmablast': '107.8', 'Non-switched memory B-cell': '39.4', 'Exhausted memory B-cell': '53.2', 'Progenitor cell': '199.2', 'Naive CD4 T-cell activated': '38.3', 'Naive CD8 T-cell activated': '35.2', 'Memory T-reg': '48.5', 'Naive T-reg': '42.6'}
|
1U35, 1ZR3, 1ZR5, 2F8N, 2FXK, 3HQH, 3HSV, 3IID, 3IIF, 3IVB, 5IIT, 5LNC, 7D3Y
|
{}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[43.4, 51.65, 50.14, 53.77, 49.45, 55.27, 58.41, 60.42, 63.59, 65.9, 73.82, 80.98, 88.74, 92.09, 92.25, 95.47, 93.55, 93.51, 94.05, 94.71, 94.97, 93.77, 96.38, 96.72, 97.82, 95.84, 96.7, 96.78, 96.94, 96.41, 96.81, 95.86, 95.69, 95.78, 93.82, 92.07, 90.32, 93.85, 93.45, 94.76, 95.3, 95.58, 92.02, 95.52, 96.26, 97.56, 97.33, 97.71, 96.67, 97.74, 96.61, 96.58, 96.96, 96.01, 95.8, 95.95, 97.38, 95.61, 95.33, 97.33, 97.71, 96.88, 97.98, 98.12, 97.99, 95.58, 95.86, 97.66, 96.4, 94.53, 95.06, 97.24, 95.87, 94.49, 98.04, 97.7, 97.57, 98.37, 97.13, 98.29, 97.97, 97.13, 96.53, 96.65, 96.47, 94.74, 94.05, 95.98, 92.11, 92.0, 95.13, 93.59, 93.19, 92.8, 95.05, 92.58, 90.17, 94.28, 93.66, 94.63, 95.87, 96.34, 94.83, 93.97, 92.72, 90.27, 87.65, 88.97, 87.95, 84.65, 82.84, 84.37, 82.31, 84.27, 78.93, 68.23, 61.84, 52.95, 52.97, 49.14, 44.81, 44.75, 41.87, 48.41, 41.91, 41.57, 42.76, 44.32, 36.84, 37.69, 36.74, 37.38, 40.69, 39.69, 36.09, 34.67, 36.23, 33.91, 31.9, 36.34, 36.14, 27.07, 31.75, 27.73, 26.84, 32.17, 26.16, 29.67, 26.98, 25.72, 29.66, 29.74, 23.67, 28.79, 25.07, 26.64, 26.63, 25.76, 30.6, 23.24, 30.13, 23.86, 29.94, 25.57, 25.51, 25.33, 28.62, 24.33, 27.63, 23.5, 29.36, 22.56, 27.97, 26.73, 27.77, 34.88, 34.48, 33.87, 40.92, 42.19, 40.69, 53.89, 67.05, 77.05, 85.27, 89.14, 90.4, 94.24, 91.71, 92.5, 88.68, 79.25, 83.25, 86.81, 92.37, 94.89, 97.1, 96.57, 96.4, 94.0, 92.81, 91.26, 89.4, 86.49, 84.32, 89.25, 90.33, 89.81, 89.24, 90.34, 92.47, 95.79, 98.59, 98.6, 98.32, 98.22, 97.1, 96.22, 95.53, 94.53, 95.68, 95.4, 95.37, 91.71, 94.66, 90.5, 89.67, 89.14, 93.35, 94.82, 94.43, 94.58, 96.88, 96.29, 95.36, 95.14, 95.23, 95.94, 96.55, 96.88, 97.8, 97.42, 97.36, 97.04, 97.44, 96.11, 95.99, 96.09, 93.03, 94.71, 94.83, 90.11, 92.85, 95.64, 96.43, 96.81, 97.55, 97.97, 97.84, 98.42, 98.33, 98.29, 97.81, 97.34, 95.3, 94.9, 94.11, 96.59, 95.56, 96.93, 97.53, 98.59, 98.55, 98.7, 98.36, 98.29, 97.68, 96.77, 97.91, 97.25, 97.36, 94.92, 95.07, 95.23, 95.81, 96.94, 97.69, 98.12, 98.6, 98.64, 98.58, 98.6, 98.79, 98.77, 98.7, 98.74, 98.82, 98.72, 98.53, 98.6, 98.63, 98.3, 97.71, 97.95, 97.83, 98.41, 97.95, 98.42, 98.47, 98.19, 97.71, 95.72, 93.98, 95.24, 91.45, 90.22, 86.74, 86.22, 93.06, 94.88, 98.04, 97.97, 97.12, 96.94, 97.14, 98.1, 98.08, 97.41, 98.13, 98.52, 97.59, 95.72, 97.7, 97.09, 93.58, 93.55, 96.5, 93.86, 89.64, 91.03, 91.07, 77.88, 86.53, 94.26, 97.13, 98.15, 95.89, 97.74, 98.14, 97.54, 97.39, 95.39, 95.14, 91.56, 91.94, 91.43, 94.1, 95.21, 95.12, 95.29, 97.63, 97.63, 95.82, 94.48, 95.62, 94.27, 91.25, 89.32, 87.04, 71.97, 57.19, 42.76]
|
[1.0, 0.94, 0.9, 0.94, 0.66, 0.82, 0.91, 0.93, 0.93, 0.86, 0.87, 0.94, 0.62, 0.51, 0.42, 0.13, 0.64, 0.7, 0.39, 0.72, 0.16, 0.84, 0.27, 0.36, 0.0, 0.45, 0.52, 0.11, 0.16, 0.67, 0.61, 0.11, 0.53, 0.82, 0.75, 0.51, 0.77, 0.99, 0.75, 0.98, 0.22, 0.58, 0.79, 0.54, 0.39, 0.0, 0.31, 0.72, 0.43, 0.0, 0.37, 0.38, 0.38, 0.22, 0.66, 0.33, 0.36, 0.53, 0.41, 0.22, 0.52, 0.64, 0.27, 0.0, 0.33, 0.44, 0.13, 0.02, 0.78, 0.77, 0.45, 0.89, 0.62, 0.99, 0.8, 0.46, 0.39, 0.39, 0.32, 0.04, 0.31, 0.16, 0.16, 0.08, 0.05, 0.26, 0.68, 0.29, 0.66, 0.63, 0.06, 0.45, 0.67, 0.62, 0.3, 0.72, 0.92, 0.57, 0.91, 0.26, 0.76, 0.8, 0.04, 0.78, 0.78, 0.4, 0.81, 0.73, 0.68, 0.59, 0.68, 0.88, 0.75, 0.52, 0.88, 0.91, 0.81, 0.96, 0.95, 0.68, 0.97, 0.53, 0.93, 0.83, 0.88, 0.74, 0.82, 0.84, 0.8, 0.9, 0.96, 0.9, 0.9, 0.94, 0.92, 0.92, 0.95, 0.9, 0.96, 0.93, 0.98, 0.99, 0.97, 1.0, 0.93, 0.99, 0.96, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 1.0, 1.0, 1.0, 0.99, 0.88, 0.98, 0.87, 0.95, 1.0, 0.99, 1.0, 0.98, 0.99, 0.91, 0.96, 0.85, 0.89, 0.77, 0.8, 0.85, 0.87, 0.8, 0.97, 0.6, 0.75, 0.94, 0.97, 0.43, 0.69, 0.39, 0.5, 0.26, 0.57, 0.18, 0.53, 0.09, 0.5, 0.46, 0.55, 0.05, 0.43, 0.0, 0.06, 0.0, 0.02, 0.5, 0.14, 0.58, 0.25, 0.46, 0.44, 0.0, 0.0, 0.31, 0.02, 0.7, 0.07, 0.19, 0.0, 0.0, 0.0, 0.0, 0.2, 0.09, 0.2, 0.36, 0.59, 0.03, 0.21, 0.1, 0.77, 0.3, 0.68, 0.04, 0.0, 0.34, 0.14, 0.0, 0.41, 0.82, 0.45, 0.07, 0.33, 0.7, 0.62, 0.0, 0.27, 0.43, 0.17, 0.06, 0.53, 0.64, 0.11, 0.21, 0.82, 0.88, 0.59, 0.26, 0.72, 0.08, 0.76, 0.51, 0.03, 0.07, 0.22, 0.03, 0.26, 0.06, 0.34, 0.07, 0.42, 0.69, 0.12, 0.47, 0.01, 0.6, 0.27, 0.0, 0.0, 0.0, 0.0, 0.08, 0.06, 0.02, 0.57, 0.41, 0.94, 0.48, 0.89, 0.69, 0.07, 0.45, 0.63, 0.26, 0.0, 0.14, 0.49, 0.0, 0.0, 0.29, 0.31, 0.0, 0.0, 0.32, 0.21, 0.01, 0.16, 0.74, 0.46, 0.74, 0.03, 0.57, 0.18, 0.0, 0.0, 0.0, 0.08, 0.2, 0.0, 0.07, 0.22, 0.71, 0.74, 0.18, 0.52, 0.04, 0.4, 0.25, 0.35, 0.22, 0.0, 0.0, 0.55, 0.08, 0.0, 0.02, 0.54, 0.0, 0.0, 0.28, 0.33, 0.13, 0.0, 0.48, 0.78, 0.3, 0.74, 0.92, 0.07, 0.25, 0.01, 0.51, 0.18, 0.01, 0.12, 0.0, 0.03, 0.03, 0.59, 0.22, 0.69, 0.61, 0.02, 0.11, 0.38, 0.11, 0.01, 0.23, 0.42, 0.08, 0.01, 0.6, 0.64, 0.16, 0.66, 0.67, 0.71]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 82.351478
| 0.476532
| 2,087
|
O43791
|
O75367-2
| null |
degron_data
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
MACROH2A1
|
MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVSKKAGGKKGARKSKKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISSYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN
|
Homo sapiens
| null |
Not found
|
{}
| null |
{}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
| null | null |
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| null | null | 2,087
|
O43791
|
O95835
|
nan, 32460168
|
degron_data, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
LATS1
|
MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTEDPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVIQALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKGSKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPPQVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGYPPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQNVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNMELYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQPSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNVTVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYPYNYPKPIEYEYINSQGSEQQSDEDDQNTGSEIKNRDLVYV
|
Homo sapiens
|
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cytoskeleton, spindle, Midbody, Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body
|
Low tissue specificity
|
{'Ciliated cells': '13.6', 'Basal respiratory cells': '8.7', 'Club cells': '12.9', 'Ionocytes': '4.8', 'Mucus glandular cells': '25.9', 'Serous glandular cells': '13.2', 'Gastric mucus-secreting cells': '23.0', 'Proximal enterocytes': '10.1', 'Paneth cells': '11.2', 'Distal enterocytes': '13.8', 'Intestinal goblet cells': '13.9', 'Exocrine glandular cells': '-0.617', 'Basal prostatic cells': '20.5', 'Prostatic glandular cells': '31.7', 'Breast glandular cells': '0.529', 'Breast myoepithelial cells': '0.585', 'Glandular and luminal cells': '16.2', 'Secretory cells': '15.2', 'Basal keratinocytes': '17.6', 'Suprabasal keratinocytes': '14.3', 'Basal squamous epithelial cells': '21.9', 'Squamous epithelial cells': '17.6', 'Alveolar cells type 1': '0.175', 'Alveolar cells type 2': '-0.225', 'Salivary duct cells': '23.7', 'Ductal cells': '0.639', 'Hepatocytes': '0.108', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.079', 'Distal tubular cells': '3.1', 'Collecting duct cells': '7.8', 'Mesothelial cells': '0.422', 'Sertoli cells': '0.240', 'Granulosa cells': '14.5', 'Enteroendocrine cells': '18.5', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.276', 'Excitatory neurons': '49.7', 'Inhibitory neurons': '45.9', 'Cone photoreceptor cells': '20.4', 'Rod photoreceptor cells': '18.8', 'Bipolar cells': '16.0', 'Horizontal cells': '17.0', 'Astrocytes': '31.3', 'Oligodendrocyte precursor cells': '51.4', 'Oligodendrocytes': '59.5', 'Microglial cells': '31.3', 'Muller glia cells': '9.3', 'Schwann cells': '0.152', 'Spermatogonia': '0.229', 'Spermatocytes': '0.210', 'Early spermatids': '0.037', 'Late spermatids': '-0.292', 'Oocytes': '4.4', 'Cytotrophoblasts': '8.2', 'Syncytiotrophoblasts': '12.6', 'Extravillous trophoblasts': '11.4', 'Endothelial cells': '17.9', 'Lymphatic endothelial cells': '24.4', 'Cardiomyocytes': '0.441', 'Skeletal myocytes': '-0.016', 'Smooth muscle cells': '18.2', 'Adipocytes': '19.7', 'Melanocytes': '0.229', 'Fibroblasts': '21.3', 'Peritubular cells': '0.428', 'Endometrial stromal cells': '22.5', 'Ovarian stromal cells': '13.4', 'Undifferentiated cells': '9.6', 'T-cells': '25.1', 'B-cells': '22.9', 'Plasma cells': '16.7', 'Nk-cells': '22.0', 'Granulocytes': '12.2', 'Monocytes': '21.2', 'Macrophages': '19.2', 'Hofbauer cells': '9.8', 'Kupffer cells': '13.1', 'Dendritic cells': '14.8', 'Langerhans cells': '0.309', 'Erythroid cells': '0.132', 'Adipocytes (Subcutaneous)': '-0.312', 'Adipocytes (Visceral)': '-0.415', 'Breast glandular cells (progenitors)': '0.400', 'Adipocytes (Breast)': '-0.527', 'Colon enterocytes': '-0.173', 'Colon enteroendocrine cells': '0.372', 'Enteric glia cells': '0.190', 'Mitotic cells (Colon)': '-0.095', 'Mitotic cells (Heart)': '0.478', 'Podocytes': '-0.056', 'Ascending Loop of Henle cells': '0.513', 'Intercalated cells': '0.030', 'Cholangiocyte': '0.238', 'NK-cells (Liver)': '-0.008', 'Respiratory ciliated cells': '0.050', 'Mitotic cells (Lung)': '-0.066', 'NK-cells (Lung)': '0.240', 'B-cells (Lung)': '0.020', 'Alpha cells': '0.441', 'Beta cells': '0.276', 'Prostate glandular cells': '-0.013', 'Prostate basal glandular cells': '0.175', 'Urothelial cells': '0.118', 'Keratinocyte (other)': '0.305', 'Keratinocyte (granular)': '-0.204', 'Hair cortex cells': '-0.003', 'Inner root sheath cells': '0.078', 'Outer root sheath cells': '0.267', 'Sebaceous gland cells': '0.167', 'Eccrine sweat gland cells': '0.108', 'Adipocytes (Skin)': '-0.096', 'Mitotic cells (Skin)': '0.476', 'Parietal cells': '-0.673', 'Chief cells': '-0.572', 'Gastric mucous cells': '-0.459', 'Gastric enteroendocrine cells': '-0.402', 'Mitotic cells (Stomach)': '-0.043', 'Parafollicular cells': '0.081', 'Thyroid glandular cells': '0.376', 'Mitotic cells (Thyroid)': '0.162', 'Adrenal cortex cells': '0.425', 'Adrenal medulla cells': '-0.024', 'Mitotic cells (Adrenal gland)': '0.209', 'Minor salivary glandular cells': '0.497', 'Minor salivary gland ductal cells': '0.387', 'Minor salivary gland basal cells': '0.171', 'Mitotic cells (Minor salivary gland)': '0.190', 'Adipocytes (Minor salivary gland)': '0.149', 'Somatotropes': '-0.155', 'Lactotropes': '-0.061', 'Gonadotropes': '0.086', 'Corticotropes': '-0.129', 'Thyrotropes': '0.165', 'Undifferentiated cells (Pituitary gland)': '0.370', 'Mitotic cells (Spleen)': '-0.162', 'Platelets': '-0.135', 'Erythrocytes': '-0.092', 'Hematopoietic stem cells': '-0.274', 'B-cells (Spleen)': '0.329', 'NK-cells (Spleen)': '0.383', 'Amygdala excitatory': '83.9', 'Cerebellar inhibitory': '69.9', 'Cge interneuron': '74.9', 'Deep-layer corticothalamic and 6b': '81.9', 'Deep-layer intratelencephalic': '83.2', 'Deep-layer near-projecting': '80.6', 'Eccentric medium spiny neuron': '82.5', 'Hippocampal ca1-3': '83.9', 'Hippocampal ca4': '80.0', 'Hippocampal dentate gyrus': '99.0', 'Lamp5-lhx6 and chandelier': '71.5', 'Lower rhombic lip': '69.7', 'Mammillary body': '84.5', 'Medium spiny neuron': '88.3', 'Mge interneuron': '76.6', 'Midbrain-derived inhibitory': '99.5', 'Miscellaneous': '75.1', 'Splatter': '67.5', 'Thalamic excitatory': '73.6', 'Upper rhombic lip': '90.4', 'Upper-layer intratelencephalic': '84.0', 'Astrocyte': '71.6', 'Bergmann glia': '89.6', 'Central nervous system macrophage': '115.4', 'Choroid plexus epithelial cell': '94.2', 'Committed oligodendrocyte precursor': '81.1', 'Ependymal cell': '63.8', 'Oligodendrocyte': '108.1', 'Oligodendrocyte precursor cell': '89.4', 'Endothelial cell': '71.1', 'Pericyte': '81.8', 'Vascular associated smooth muscle cell': '64.9', 'Fibroblast': '92.1', 'Leukocyte': '93.5', 'Basophil': '36.3', 'Eosinophil': '4.8', 'Neutrophil': '19.9', 'Classical monocyte': '20.8', 'Non-classical monocyte': '42.7', 'Intermediate monocyte': '31.7', 'T-reg': '38.7', 'GdT-cell': '5.9', 'MAIT T-cell': '38.6', 'Memory CD4 T-cell': '4.5', 'Naive CD4 T-cell': '57.2', 'Memory CD8 T-cell': '5.0', 'Naive CD8 T-cell': '45.5', 'Memory B-cell': '3.8', 'Naive B-cell': '49.5', 'Plasmacytoid DC': '28.6', 'Myeloid DC': '21.3', 'NK-cell': '49.7', 'Total PBMC': '24.4', 'Vd2 gdTCR': '33.8', 'Memory CD4 T-cell Th1\\/Th17': '55.8', 'Memory CD4 T-cell Th17': '47.4', 'Memory CD4 T-cell Th2': '52.9', 'Non-Vd2 gdTCR': '35.6', 'Memory CD4 T-cell Th1': '45.8', 'Memory CD4 T-cell TFH': '41.7', 'Terminal effector memory CD4 T-cell': '40.1', 'Central memory CD8 T-cell': '39.1', 'Effector memory CD8 T-cell': '44.2', 'Terminal effector memory CD8 T-cell': '44.2', 'Non-switched memory B-cell': '30.3', 'Plasmablast': '21.6', 'Switched memory B-cell': '31.5', 'Exhausted memory B-cell': '29.0', 'Progenitor cell': '27.6', 'Memory T-reg': '39.8', 'Naive CD4 T-cell activated': '64.6', 'Naive CD8 T-cell activated': '55.7', 'Naive T-reg': '66.1'}
|
4ZRK, 5B5W, 5BRK, 7LWH
|
{'Adipose Tissue': 12.354970099667774, 'Adrenal Gland': 8.551728682170543, 'Bladder': 13.763000000000002, 'Blood': 4.494459741657697, 'Blood Vessel': 14.032024719101123, 'Brain': 6.72839061317184, 'Breast': 13.077063180827889, 'Cervix Uteri': 17.890105263157892, 'Colon': 11.171002567394094, 'Esophagus': 10.73021107266436, 'Fallopian Tube': 15.964444444444446, 'Heart': 3.946680952380952, 'Kidney': 5.10076404494382, 'Liver': 3.743814159292035, 'Lung': 12.449525951557094, 'Muscle': 5.052626400996264, 'Nerve': 16.51468012924071, 'Ovary': 18.94773888888889, 'Pancreas': 4.097420731707317, 'Pituitary': 9.958526501766784, 'Prostate': 12.975902040816326, 'Salivary Gland': 10.138, 'Skin': 11.97750414593698, 'Small Intestine': 10.418673796791444, 'Spleen': 10.523576763485476, 'Stomach': 7.8934958217270195, 'Testis': 11.357551246537396, 'Thyroid': 12.752376722817765, 'Uterus': 18.963380281690142, 'Vagina': 14.340108974358971}
|
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0.76, 0.72, 0.6, 0.64, 0.2, 0.38, 0.23, 0.34, 0.33, 0.69, 0.71, 0.57, 0.59, 0.22, 0.13, 0.26, 0.25, 0.12, 0.06, 0.32, 0.14, 0.03, 0.29, 0.05, 0.15, 0.1, 0.15, 0.15, 0.2, 0.36, 0.68, 0.21, 0.63, 0.21, 0.72, 0.64, 0.76, 0.52, 0.76, 0.8, 0.61, 0.66, 0.75, 0.82, 0.81, 0.76, 0.78, 0.77, 0.89, 0.9, 1.0, 0.99, 1.0, 0.91, 1.0, 0.91, 1.0, 0.9, 1.0, 0.89, 1.0, 1.0, 0.99, 1.0, 0.97, 0.95, 0.98, 0.87, 1.0, 0.91, 0.96, 0.89, 0.98, 0.91]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 55.737628
| 0.65123
| 386
|
O43791
|
P03372
|
nan, 25766326, E3Net, nan
|
degron_data, UbiNet, UbiBrowser, 31181401, degron_data
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
ESR1
|
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
|
Homo sapiens
|
Nucleus, Cytoplasm, Cell membrane, Nucleus, Cytoplasm, Cell membrane, Cell membrane, Nucleus, Golgi apparatus, Cell membrane
|
Tissue enhanced (cervix, endometrium, fallopian tube)
|
{'Ciliated cells': '29.9', 'Basal respiratory cells': '0.0', 'Club cells': '2.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.3', 'Serous glandular cells': '0.4', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.1', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.296', 'Basal prostatic cells': '1.3', 'Prostatic glandular cells': '0.9', 'Breast glandular cells': '0.690', 'Breast myoepithelial cells': '0.589', 'Glandular and luminal cells': '95.3', 'Secretory cells': '73.5', 'Basal keratinocytes': '0.5', 'Suprabasal keratinocytes': '0.4', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.4', 'Alveolar cells type 1': '0.138', 'Alveolar cells type 2': '-0.484', 'Salivary duct cells': '0.4', 'Ductal cells': '0.389', 'Hepatocytes': '0.758', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.084', 'Distal tubular cells': '3.1', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.369', 'Sertoli cells': '-0.512', 'Granulosa cells': '6.3', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '-0.388', 'Excitatory neurons': '4.3', 'Inhibitory neurons': '5.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '7.2', 'Bipolar cells': '4.8', 'Horizontal cells': '12.6', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '23.6', 'Oligodendrocytes': '0.6', 'Microglial cells': '0.9', 'Muller glia cells': '2.5', 'Schwann cells': '0.066', 'Spermatogonia': '-0.201', 'Spermatocytes': '0.028', 'Early spermatids': '0.548', 'Late spermatids': '0.615', 'Oocytes': '0.7', 'Cytotrophoblasts': '0.1', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '1.9', 'Lymphatic endothelial cells': '2.0', 'Cardiomyocytes': '0.314', 'Skeletal myocytes': '0.667', 'Smooth muscle cells': '11.5', 'Adipocytes': '1.1', 'Melanocytes': '0.079', 'Fibroblasts': '20.3', 'Peritubular cells': '-0.227', 'Endometrial stromal cells': '72.4', 'Ovarian stromal cells': '5.4', 'Undifferentiated cells': '0.0', 'T-cells': '2.2', 'B-cells': '1.4', 'Plasma cells': '11.3', 'Nk-cells': '0.2', 'Granulocytes': '2.5', 'Monocytes': '0.2', 'Macrophages': '3.3', 'Hofbauer cells': '0.9', 'Kupffer cells': '2.5', 'Dendritic cells': '0.0', 'Langerhans cells': '0.323', 'Erythroid cells': '0.070', 'Adipocytes (Subcutaneous)': '-0.074', 'Adipocytes (Visceral)': '-0.071', 'Breast glandular cells (progenitors)': '0.392', 'Adipocytes (Breast)': '-0.532', 'Colon enterocytes': '-0.071', 'Colon enteroendocrine cells': '0.258', 'Enteric glia cells': '0.545', 'Mitotic cells (Colon)': '-0.016', 'Mitotic cells (Heart)': '0.252', 'Podocytes': '-0.017', 'Ascending Loop of Henle cells': '0.523', 'Intercalated cells': '0.158', 'Cholangiocyte': '-0.196', 'NK-cells (Liver)': '0.372', 'Respiratory ciliated cells': '0.020', 'Mitotic cells (Lung)': '-0.106', 'NK-cells (Lung)': '0.439', 'B-cells (Lung)': '0.266', 'Alpha cells': '0.412', 'Beta cells': '0.305', 'Prostate glandular cells': '-0.091', 'Prostate basal glandular cells': '0.060', 'Urothelial cells': '0.130', 'Keratinocyte (other)': '0.053', 'Keratinocyte (granular)': '-0.218', 'Hair cortex cells': '0.000', 'Inner root sheath cells': '-0.055', 'Outer root sheath cells': '0.257', 'Sebaceous gland cells': '0.269', 'Eccrine sweat gland cells': '0.141', 'Adipocytes (Skin)': '0.079', 'Mitotic cells (Skin)': '0.181', 'Parietal cells': '-0.564', 'Chief cells': '-0.492', 'Gastric mucous cells': '-0.470', 'Gastric enteroendocrine cells': '-0.305', 'Mitotic cells (Stomach)': '-0.142', 'Parafollicular cells': '0.071', 'Thyroid glandular cells': '0.288', 'Mitotic cells (Thyroid)': '0.212', 'Adrenal cortex cells': '0.458', 'Adrenal medulla cells': '-0.120', 'Mitotic cells (Adrenal gland)': '0.038', 'Minor salivary glandular cells': '0.069', 'Minor salivary gland ductal cells': '0.309', 'Minor salivary gland basal cells': '-0.035', 'Mitotic cells (Minor salivary gland)': '0.105', 'Adipocytes (Minor salivary gland)': '0.225', 'Somatotropes': '0.134', 'Lactotropes': '0.510', 'Gonadotropes': '0.719', 'Corticotropes': '-0.026', 'Thyrotropes': '0.179', 'Undifferentiated cells (Pituitary gland)': '-0.029', 'Mitotic cells (Spleen)': '0.108', 'Platelets': '-0.193', 'Erythrocytes': '0.014', 'Hematopoietic stem cells': '-0.184', 'B-cells (Spleen)': '0.153', 'NK-cells (Spleen)': '0.222', 'Amygdala excitatory': '87.2', 'Cerebellar inhibitory': '5.8', 'Cge interneuron': '9.8', 'Deep-layer corticothalamic and 6b': '8.0', 'Deep-layer intratelencephalic': '29.4', 'Deep-layer near-projecting': '4.6', 'Eccentric medium spiny neuron': '19.6', 'Hippocampal ca1-3': '36.2', 'Hippocampal ca4': '23.0', 'Hippocampal dentate gyrus': '30.8', 'Lamp5-lhx6 and chandelier': '17.8', 'Lower rhombic lip': '5.4', 'Mammillary body': '11.5', 'Medium spiny neuron': '10.4', 'Mge interneuron': '8.5', 'Midbrain-derived inhibitory': '16.7', 'Miscellaneous': '13.7', 'Splatter': '34.8', 'Thalamic excitatory': '11.8', 'Upper rhombic lip': '8.9', 'Upper-layer intratelencephalic': '20.2', 'Astrocyte': '18.6', 'Bergmann glia': '14.9', 'Central nervous system macrophage': '42.0', 'Choroid plexus epithelial cell': '70.1', 'Committed oligodendrocyte precursor': '17.7', 'Ependymal cell': '83.4', 'Oligodendrocyte': '2.0', 'Oligodendrocyte precursor cell': '40.5', 'Endothelial cell': '3.5', 'Pericyte': '30.6', 'Vascular associated smooth muscle cell': '22.5', 'Fibroblast': '20.2', 'Leukocyte': '21.2', 'Basophil': '0.2', 'Eosinophil': '0.0', 'Neutrophil': '2.2', 'Classical monocyte': '0.5', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '0.8', 'T-reg': '3.1', 'GdT-cell': '0.0', 'MAIT T-cell': '2.6', 'Memory CD4 T-cell': '0.2', 'Naive CD4 T-cell': '6.3', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '4.4', 'Memory B-cell': '0.1', 'Naive B-cell': '3.4', 'Plasmacytoid DC': '0.4', 'Myeloid DC': '1.7', 'NK-cell': '4.7', 'Total PBMC': '1.8', 'Vd2 gdTCR': '2.0', 'Memory CD4 T-cell TFH': '4.6', 'Memory CD4 T-cell Th2': '6.1', 'Memory CD4 T-cell Th17': '3.8', 'Memory CD4 T-cell Th1\\/Th17': '3.3', 'Non-Vd2 gdTCR': '2.9', 'Memory CD4 T-cell Th1': '4.4', 'Terminal effector memory CD4 T-cell': '6.7', 'Central memory CD8 T-cell': '3.6', 'Effector memory CD8 T-cell': '2.0', 'Terminal effector memory CD8 T-cell': '2.6', 'Switched memory B-cell': '1.7', 'Plasmablast': '17.6', 'Non-switched memory B-cell': '3.3', 'Exhausted memory B-cell': '3.6', 'Progenitor cell': '1.0', 'Naive CD4 T-cell activated': '0.9', 'Naive CD8 T-cell activated': '0.4', 'Memory T-reg': '4.2', 'Naive T-reg': '4.9'}
|
1A52, 1ERE, 1ERR, 1G50, 1GWQ, 1GWR, 1HCP, 1HCQ, 1L2I, 1PCG, 1QKT, 1QKU, 1R5K, 1SJ0, 1UOM, 1X7E, 1X7R, 1XP1, 1XP6, 1XP9, 1XPC, 1XQC, 1YIM, 1YIN, 1ZKY, 2AYR, 2B1V, 2B1Z, 2B23, 2BJ4, 2FAI, 2G44, 2G5O, 2I0J, 2IOG, 2IOK, 2JF9, 2JFA, 2LLO, 2LLQ, 2OCF, 2OUZ, 2P15, 2POG, 2Q6J, 2Q70, 2QA6, 2QA8, 2QAB, 2QE4, 2QGT, 2QGW, 2QH6, 2QR9, 2QSE, 2QXM, 2QXS, 2QZO, 2R6W, 2R6Y, 2YAT, 2YJA, 3CBM, 3CBO, 3CBP, 3DT3, 3ERD, 3ERT, 3HLV, 3HM1, 3L03, 3OS8, 3OS9, 3OSA, 3Q95, 3UU7, 3UUA, 3UUC, 3UUD, 4AA6, 4DMA, 4IU7, 4IUI, 4IV2, 4IV4, 4IVW, 4IVY, 4IW6, 4IW8, 4IWC, 4IWF, 4JC3, 4JDD, 4MG5, 4MG6, 4MG7, 4MG8, 4MG9, 4MGA, 4MGB, 4MGC, 4MGD, 4O6F, 4PP6, 4PPP, 4PPS, 4PXM, 4Q13, 4Q50, 4TUZ, 4TV1, 4XI3, 4ZN7, 4ZN9, 4ZNH, 4ZNS, 4ZNT, 4ZNU, 4ZNV, 4ZNW, 5AAU, 5AAV, 5ACC, 5AK2, 5DI7, 5DID, 5DIE, 5DIG, 5DK9, 5DKB, 5DKE, 5DKG, 5DKS, 5DL4, 5DLR, 5DMC, 5DMF, 5DP0, 5DRJ, 5DRM, 5DTV, 5DU5, 5DUE, 5DUG, 5DUH, 5DVS, 5DVV, 5DWE, 5DWG, 5DWI, 5DWJ, 5DX3, 5DXB, 5DXE, 5DXG, 5DXK, 5DXM, 5DXP, 5DXQ, 5DXR, 5DY8, 5DYB, 5DYD, 5DZ0, 5DZ1, 5DZ3, 5DZH, 5DZI, 5E0W, 5E0X, 5E14, 5E15, 5E19, 5E1C, 5EGV, 5EHJ, 5EI1, 5EIT, 5FQP, 5FQR, 5FQS, 5FQT, 5FQV, 5GS4, 5GTR, 5HYR, 5JMM, 5KCC, 5KCD, 5KCE, 5KCF, 5KCT, 5KCU, 5KCW, 5KD9, 5KR9, 5KRA, 5KRC, 5KRF, 5KRH, 5KRI, 5KRJ, 5KRK, 5KRL, 5KRM, 5KRO, 5N10, 5T0X, 5T1Z, 5T92, 5T97, 5TLD, 5TLF, 5TLG, 5TLL, 5TLM, 5TLO, 5TLP, 5TLT, 5TLU, 5TLV, 5TLX, 5TLY, 5TM1, 5TM2, 5TM3, 5TM4, 5TM5, 5TM6, 5TM7, 5TM8, 5TM9, 5TML, 5TMM, 5TMO, 5TMQ, 5TMR, 5TMS, 5TMT, 5TMU, 5TMV, 5TMW, 5TMZ, 5TN1, 5TN3, 5TN4, 5TN5, 5TN6, 5TN7, 5TN8, 5TN9, 5TNB, 5U2B, 5U2D, 5UFW, 5UFX, 5W9C, 5W9D, 5WGD, 5WGQ, 6B0F, 6C42, 6CBZ, 6CHW, 6CHZ, 6CZN, 6D0F, 6DF6, 6DFN, 6HHP, 6HKB, 6HKF, 6HMU, 6IAR, 6OWC, 6PET, 6PFM, 6PIT, 6PSJ, 6SBO, 6SQ0, 6SUO, 6TJM, 6TL3, 6V87, 6V8T, 6VGH, 6VJD, 6VPF, 6WOK, 6ZOQ, 6ZOR, 6ZOS, 7B9M, 7B9R, 7B9T, 7BA3, 7BA5, 7BA6, 7BA7, 7BA8, 7BA9, 7BAA, 7BAB, 7JHD, 7KBS, 7MSA, 7N9O, 7NDO, 7NEL, 7NFB, 7NFW, 7NIZ, 7OPW, 7OQ7, 7OQ8, 7PWT, 7PWZ, 7QVJ, 7QVL, 7R62, 7RKE, 7RNM, 7RRX, 7RRY, 7RRZ, 7RS0, 7RS1, 7RS2, 7RS3, 7RS4, 7RS7, 7RS8, 7RS9, 7SFO, 7T2X, 7TE7, 7UJ7, 7UJ8, 7UJC, 7UJF, 7UJM, 7UJO, 7UJW, 7UJY, 7WNV, 7Y8F, 7Y8G, 7YMK, 8AFN, 8AI0, 8ALR, 8ALT, 8ALV, 8ALW, 8AM7, 8ANF, 8AOY, 8APS, 8AQ1, 8AQC, 8AQE, 8AQZ, 8AR4, 8AR5, 8ARG, 8ARO, 8ARQ, 8ARR, 8ARW, 8ARX, 8ARY, 8ARZ, 8AS1, 8AT9, 8ATP, 8AU2, 8AUS, 8AUY, 8AV3, 8AV4, 8AV7, 8AV8, 8AWG, 8AXE, 8AXU, 8AZE, 8B39, 8BWJ, 8BWX, 8BWZ, 8BX0, 8BX3, 8BX4, 8BXI, 8BXM, 8BXN, 8BXO, 8BXQ, 8BXS, 8BY9, 8BYB, 8BYC, 8BYD, 8BYE, 8BYF, 8BYG, 8BYO, 8BYY, 8BYZ, 8BZ0, 8BZ9, 8BZA, 8BZB, 8BZC, 8BZF, 8BZW, 8C04, 8C0K, 8C42, 8C4F, 8C4G, 8DU6, 8DU8, 8DU9, 8DUB, 8DUC, 8DUD, 8DUG, 8DUH, 8DUI, 8DUK, 8DUS, 8DV5, 8DV7, 8DV8, 8DVB, 8EV1, 8EV2, 8VYT, 8VYX, 8VZ0, 8VZ1, 8VZP, 8VZQ, 8W03, 8W07, 9BQE, 9BU1
|
{'Adipose Tissue': 2.1268105481727577, 'Adrenal Gland': 1.194286046511628, 'Bladder': 2.2000619047619048, 'Blood': 0.147215219590958, 'Blood Vessel': 3.1661319101123597, 'Brain': 0.417679452687358, 'Breast': 15.190423747276688, 'Cervix Uteri': 80.88842105263159, 'Colon': 0.5639993581514763, 'Esophagus': 0.7822738339100347, 'Fallopian Tube': 42.626666666666665, 'Heart': 0.619876806039489, 'Kidney': 1.0101966292134832, 'Liver': 3.5546641592920354, 'Lung': 2.1247008650519033, 'Muscle': 0.8011335242839351, 'Nerve': 2.4361403877221326, 'Ovary': 8.171872222222222, 'Pancreas': 0.2713894817073171, 'Pituitary': 6.598886219081272, 'Prostate': 6.334018775510204, 'Salivary Gland': 0.6298580246913581, 'Skin': 0.7955200386954118, 'Small Intestine': 0.7281461497326204, 'Spleen': 1.511657676348548, 'Stomach': 0.4769661838440112, 'Testis': 2.8383019390581716, 'Thyroid': 2.8016070444104133, 'Uterus': 70.5287323943662, 'Vagina': 50.442493589743584}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[35.33, 25.94, 30.84, 30.42, 29.22, 38.45, 33.48, 31.3, 32.69, 41.3, 36.34, 39.65, 42.89, 42.51, 38.01, 43.24, 45.15, 40.56, 43.57, 37.52, 36.31, 36.13, 27.98, 30.43, 30.44, 30.35, 25.93, 29.13, 29.73, 27.49, 29.01, 28.8, 31.64, 31.76, 31.92, 31.31, 31.06, 29.48, 35.18, 31.51, 29.13, 33.83, 34.7, 31.35, 31.09, 33.64, 31.9, 32.78, 30.63, 33.01, 29.12, 29.22, 27.82, 30.85, 34.03, 29.04, 29.1, 31.46, 27.24, 29.89, 26.35, 30.9, 27.96, 29.6, 30.75, 28.81, 30.36, 35.22, 34.5, 31.14, 36.65, 33.69, 35.68, 35.45, 33.92, 35.98, 38.58, 33.84, 47.62, 38.22, 40.38, 49.15, 39.06, 41.18, 40.31, 41.18, 40.44, 40.57, 39.95, 36.45, 37.78, 38.05, 41.71, 41.49, 37.71, 38.92, 40.39, 49.53, 43.35, 38.69, 34.2, 32.96, 36.43, 34.16, 34.33, 32.02, 39.15, 38.08, 30.61, 31.21, 33.98, 32.77, 40.3, 41.48, 39.3, 34.15, 32.44, 30.64, 30.47, 33.31, 33.15, 28.42, 35.7, 33.68, 31.52, 34.03, 30.82, 31.5, 35.61, 31.97, 32.75, 39.2, 36.08, 32.63, 38.13, 35.48, 38.24, 37.7, 33.55, 36.39, 39.06, 34.87, 37.43, 39.07, 39.61, 40.86, 39.85, 41.9, 35.06, 30.02, 37.51, 44.57, 37.23, 40.93, 40.18, 46.05, 38.47, 39.79, 41.21, 35.14, 41.92, 37.46, 46.08, 40.32, 41.78, 44.08, 38.44, 51.84, 38.06, 49.84, 40.77, 41.34, 35.69, 44.11, 37.61, 35.81, 36.33, 44.47, 48.63, 57.84, 72.22, 81.9, 91.91, 96.84, 98.15, 96.82, 97.9, 97.85, 96.38, 96.81, 97.09, 97.13, 95.11, 93.54, 94.74, 95.13, 94.61, 91.52, 94.56, 97.01, 97.26, 98.2, 97.52, 97.46, 98.23, 96.92, 95.66, 97.37, 96.07, 94.06, 94.41, 93.82, 89.28, 82.48, 74.73, 64.4, 76.29, 83.43, 92.75, 91.62, 95.31, 91.85, 89.95, 91.93, 90.73, 93.06, 95.25, 95.06, 96.49, 96.39, 95.97, 95.28, 94.12, 95.77, 95.58, 95.18, 96.56, 96.34, 96.06, 97.28, 97.87, 96.33, 95.31, 97.07, 96.79, 95.11, 95.05, 95.34, 92.49, 94.66, 88.04, 76.61, 70.52, 53.13, 43.73, 49.63, 47.75, 41.03, 41.64, 37.43, 33.97, 36.31, 35.46, 36.47, 45.99, 38.35, 37.21, 34.83, 37.47, 35.62, 35.23, 43.55, 46.1, 41.32, 38.34, 43.7, 38.78, 37.91, 37.73, 41.47, 36.31, 42.61, 36.74, 40.56, 40.28, 43.88, 38.59, 36.61, 37.0, 39.66, 32.31, 33.67, 37.32, 31.26, 41.75, 39.14, 33.71, 38.47, 31.96, 37.1, 37.26, 44.74, 53.47, 59.19, 71.7, 84.25, 85.39, 90.98, 93.61, 95.01, 96.92, 97.1, 97.0, 97.59, 97.69, 98.12, 98.0, 97.64, 98.14, 98.0, 97.28, 97.41, 97.81, 96.9, 96.25, 95.49, 97.06, 97.14, 96.15, 94.5, 94.91, 92.16, 88.86, 91.81, 89.29, 89.1, 91.84, 91.97, 93.13, 92.45, 93.2, 93.82, 94.58, 94.21, 95.01, 96.07, 96.13, 95.91, 97.3, 97.51, 96.45, 96.71, 97.8, 97.56, 96.73, 97.84, 98.22, 96.68, 95.85, 98.37, 97.65, 96.57, 97.03, 97.06, 95.75, 91.63, 93.49, 93.36, 88.79, 87.95, 87.23, 88.75, 86.13, 85.36, 91.59, 91.03, 88.35, 91.89, 94.2, 92.27, 91.25, 94.76, 96.85, 97.15, 97.54, 98.16, 98.3, 98.25, 98.35, 98.37, 98.55, 98.54, 98.28, 97.98, 98.25, 97.15, 95.93, 96.71, 95.13, 94.37, 97.42, 98.24, 98.21, 97.89, 97.82, 97.01, 96.34, 96.66, 96.7, 96.12, 94.58, 93.05, 91.56, 90.78, 84.07, 89.74, 89.74, 92.04, 90.78, 89.74, 92.56, 93.57, 94.22, 96.35, 96.97, 96.87, 97.48, 98.1, 97.56, 97.59, 98.03, 97.95, 97.45, 97.2, 97.59, 97.08, 95.98, 95.05, 96.34, 97.21, 97.36, 97.47, 98.24, 98.15, 98.39, 98.46, 98.37, 98.13, 97.84, 97.44, 96.85, 96.39, 95.62, 92.65, 87.28, 73.85, 62.32, 57.64, 50.74, 49.78, 42.08, 39.3, 41.26, 42.64, 48.28, 46.78, 51.56, 52.33, 60.28, 62.69, 64.97, 70.18, 81.2, 84.95, 86.65, 87.71, 92.04, 92.67, 94.37, 94.59, 96.1, 96.79, 96.9, 97.17, 98.15, 97.89, 97.66, 97.87, 97.81, 97.54, 97.59, 96.82, 96.05, 96.77, 96.84, 97.26, 95.67, 95.61, 96.58, 96.79, 94.24, 96.04, 97.17, 97.57, 96.36, 96.04, 96.77, 95.63, 95.56, 94.94, 94.59, 93.89, 94.75, 96.76, 94.67, 95.16, 96.16, 95.86, 93.41, 95.36, 95.61, 94.02, 93.13, 93.91, 94.23, 92.51, 92.0, 91.13, 90.98, 91.02, 91.36, 90.7, 87.88, 87.06, 87.73, 89.42, 91.69, 92.89, 93.92, 94.62, 93.31, 92.88, 93.62, 92.77, 89.25, 85.69, 76.57, 69.91, 52.79, 52.19, 46.42, 36.15, 36.78, 32.2, 35.73, 33.61, 28.71, 33.02, 35.21, 34.76, 36.16, 31.74, 38.59, 33.94, 40.6, 34.35, 39.49, 37.75, 37.02, 37.7, 39.7, 38.42, 38.23, 39.45, 38.9, 36.68, 37.47, 36.12, 31.04, 32.68, 33.83, 33.71, 28.59, 39.79, 30.17, 34.77, 35.96, 35.07, 38.05, 41.8, 35.99, 49.9, 41.88, 41.67, 46.92]
|
[0.94, 0.98, 0.89, 0.9, 0.96, 0.89, 0.95, 0.97, 0.83, 0.55, 0.14, 0.5, 0.48, 0.42, 0.22, 0.51, 0.68, 0.26, 0.5, 0.82, 0.8, 0.97, 0.91, 0.89, 0.9, 0.88, 0.93, 0.96, 0.94, 0.83, 0.87, 0.82, 0.88, 0.84, 0.97, 0.91, 0.92, 0.96, 0.82, 1.0, 0.93, 0.94, 1.0, 0.95, 0.99, 1.0, 1.0, 0.99, 0.96, 0.92, 0.87, 0.93, 0.9, 0.96, 1.0, 1.0, 1.0, 0.71, 0.99, 0.87, 0.98, 0.97, 0.96, 0.95, 0.99, 1.0, 1.0, 0.99, 1.0, 0.98, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.96, 1.0, 0.95, 1.0, 0.98, 0.99, 0.9, 0.99, 0.93, 0.84, 0.89, 0.8, 0.9, 0.84, 0.89, 0.89, 0.82, 0.91, 0.61, 0.81, 0.85, 0.87, 0.98, 0.9, 0.99, 0.98, 0.96, 0.92, 0.9, 0.81, 0.82, 0.95, 0.97, 0.98, 0.98, 1.0, 0.99, 0.97, 0.99, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.84, 1.0, 0.89, 0.99, 0.95, 1.0, 0.99, 0.98, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.9, 1.0, 0.89, 0.95, 1.0, 0.92, 1.0, 1.0, 0.97, 1.0, 0.93, 1.0, 0.97, 0.9, 0.89, 0.93, 0.61, 0.88, 0.82, 0.66, 0.64, 0.44, 0.51, 0.0, 0.4, 0.03, 0.03, 0.7, 0.13, 0.62, 0.25, 0.47, 0.17, 0.5, 0.21, 0.26, 0.34, 0.06, 0.44, 0.0, 0.04, 0.46, 0.42, 0.0, 0.27, 0.37, 0.06, 0.01, 0.47, 0.62, 0.1, 0.17, 0.69, 0.55, 0.78, 0.34, 0.68, 0.24, 0.85, 0.22, 0.78, 0.56, 0.84, 0.45, 0.81, 0.32, 0.66, 0.18, 0.34, 0.51, 0.83, 0.61, 0.16, 0.86, 0.7, 0.03, 0.5, 0.12, 0.04, 0.09, 0.14, 0.37, 0.34, 0.0, 0.51, 0.54, 0.29, 0.28, 0.03, 0.51, 0.69, 0.55, 0.62, 0.85, 0.68, 0.94, 0.58, 0.97, 0.78, 0.97, 0.93, 1.0, 1.0, 0.98, 0.98, 0.96, 0.99, 0.97, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 0.99, 0.97, 0.97, 0.89, 0.91, 0.89, 0.86, 0.92, 0.78, 0.91, 0.78, 0.8, 0.85, 0.89, 0.78, 0.14, 0.69, 0.03, 0.35, 0.66, 0.18, 0.53, 0.18, 0.47, 0.5, 0.0, 0.09, 0.44, 0.29, 0.02, 0.47, 0.53, 0.03, 0.34, 0.47, 0.58, 0.77, 0.16, 0.63, 0.09, 0.6, 0.35, 0.36, 0.7, 0.85, 0.74, 0.84, 0.3, 0.47, 0.26, 0.44, 0.36, 0.0, 0.06, 0.26, 0.08, 0.15, 0.04, 0.06, 0.04, 0.17, 0.14, 0.32, 0.2, 0.03, 0.39, 0.34, 0.04, 0.11, 0.37, 0.03, 0.0, 0.31, 0.51, 0.02, 0.12, 0.08, 0.01, 0.58, 0.51, 0.08, 0.38, 0.34, 0.61, 0.11, 0.15, 0.16, 0.13, 0.05, 0.07, 0.24, 0.12, 0.0, 0.01, 0.16, 0.03, 0.04, 0.13, 0.08, 0.0, 0.16, 0.08, 0.0, 0.28, 0.3, 0.03, 0.15, 0.75, 0.35, 0.87, 0.48, 0.43, 0.0, 0.19, 0.11, 0.01, 0.47, 0.32, 0.03, 0.44, 0.01, 0.26, 0.42, 0.57, 0.31, 0.01, 0.51, 0.3, 0.01, 0.64, 0.54, 0.1, 0.26, 0.55, 0.09, 0.02, 0.34, 0.25, 0.05, 0.16, 0.57, 0.05, 0.04, 0.45, 0.34, 0.0, 0.49, 0.76, 0.16, 0.6, 0.05, 0.58, 0.25, 0.39, 0.05, 0.05, 0.03, 0.0, 0.0, 0.05, 0.01, 0.05, 0.04, 0.0, 0.02, 0.49, 0.01, 0.12, 0.18, 0.79, 0.59, 0.31, 0.58, 0.98, 0.71, 0.4, 0.32, 0.82, 0.24, 0.79, 0.68, 0.32, 0.25, 0.43, 0.17, 0.09, 0.46, 0.53, 0.02, 0.12, 0.58, 0.22, 0.0, 0.29, 0.62, 0.01, 0.0, 0.25, 0.41, 0.14, 0.02, 0.48, 0.64, 0.65, 0.72, 0.29, 0.56, 0.6, 0.68, 0.46, 0.1, 0.56, 0.48, 0.16, 0.14, 0.43, 0.48, 0.0, 0.36, 0.56, 0.0, 0.13, 0.59, 0.43, 0.0, 0.39, 0.53, 0.01, 0.02, 0.51, 0.38, 0.1, 0.09, 0.7, 0.14, 0.12, 0.25, 0.43, 0.02, 0.23, 0.54, 0.46, 0.74, 0.26, 0.16, 0.9, 0.19, 0.43, 0.71, 0.13, 0.01, 0.31, 0.4, 0.12, 0.01, 0.39, 0.05, 0.22, 0.56, 0.84, 0.28, 0.52, 0.89, 0.74, 0.87, 0.89, 0.84, 0.9, 0.88, 0.81, 0.84, 0.84, 0.91, 0.83, 1.0, 0.92, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.93, 1.0, 0.9, 0.96, 0.94, 0.92, 0.98, 1.0, 1.0, 1.0, 0.94, 0.99, 0.95, 0.98, 1.0, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 66.210706
| 0.596319
| 1,258
|
O43791
|
P05412
|
19164706, E3Net
|
UbiNet, UbiBrowser, 31181401
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
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Homo sapiens
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Nucleus, Nucleus speckle, Cytoplasm
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Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
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2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
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{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
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JUN
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MTAKMETTFYDDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDLLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAELHSQNTLPSVTSAAQPVNGAGMVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGALSSGGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPGETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
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Homo sapiens
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Nucleus
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Low tissue specificity
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{'Ciliated cells': '913.1', 'Basal respiratory cells': '724.6', 'Club cells': '1523.8', 'Ionocytes': '740.0', 'Mucus glandular cells': '1260.3', 'Serous glandular cells': '1758.5', 'Gastric mucus-secreting cells': '2337.0', 'Proximal enterocytes': '1564.8', 'Paneth cells': '1318.3', 'Distal enterocytes': '1643.7', 'Intestinal goblet cells': '2569.1', 'Exocrine glandular cells': '-0.113', 'Basal prostatic cells': '2055.5', 'Prostatic glandular cells': '1056.5', 'Breast glandular cells': '0.374', 'Breast myoepithelial cells': '0.524', 'Glandular and luminal cells': '1844.1', 'Secretory cells': '1898.4', 'Basal keratinocytes': '1042.3', 'Suprabasal keratinocytes': '1282.5', 'Basal squamous epithelial cells': '1988.0', 'Squamous epithelial cells': '2052.8', 'Alveolar cells type 1': '0.148', 'Alveolar cells type 2': '-0.221', 'Salivary duct cells': '1897.1', 'Ductal cells': '0.206', 'Hepatocytes': '0.006', 'Cholangiocytes': '1413.7', 'Proximal tubular cells': '0.097', 'Distal tubular cells': '52.2', 'Collecting duct cells': '110.9', 'Mesothelial cells': '0.262', 'Sertoli cells': '0.359', 'Granulosa cells': '2951.9', 'Enteroendocrine cells': '1836.0', 'Pancreatic endocrine cells': '234.3', 'Leydig cells': '0.457', 'Excitatory neurons': '11.8', 'Inhibitory neurons': '4.7', 'Cone photoreceptor cells': '130.8', 'Rod photoreceptor cells': '423.7', 'Bipolar cells': '96.9', 'Horizontal cells': '108.3', 'Astrocytes': '178.0', 'Oligodendrocyte precursor cells': '16.5', 'Oligodendrocytes': '9.4', 'Microglial cells': '62.6', 'Muller glia cells': '1200.6', 'Schwann cells': '0.026', 'Spermatogonia': '0.116', 'Spermatocytes': '-0.303', 'Early spermatids': '-0.458', 'Late spermatids': '-0.493', 'Oocytes': '130.9', 'Cytotrophoblasts': '666.6', 'Syncytiotrophoblasts': '405.9', 'Extravillous trophoblasts': '61.9', 'Endothelial cells': '1488.8', 'Lymphatic endothelial cells': '1983.4', 'Cardiomyocytes': '0.258', 'Skeletal myocytes': '0.202', 'Smooth muscle cells': '2557.4', 'Adipocytes': '2357.2', 'Melanocytes': '0.204', 'Fibroblasts': '2580.9', 'Peritubular cells': '0.490', 'Endometrial stromal cells': '2873.0', 'Ovarian stromal cells': '5164.4', 'Undifferentiated cells': '1363.2', 'T-cells': '1163.4', 'B-cells': '806.5', 'Plasma cells': '1901.7', 'Nk-cells': '129.3', 'Granulocytes': '1311.7', 'Monocytes': '244.1', 'Macrophages': '1312.3', 'Hofbauer cells': '646.1', 'Kupffer cells': '512.2', 'Dendritic cells': '16.6', 'Langerhans cells': '0.152', 'Erythroid cells': '0.274', 'Adipocytes (Subcutaneous)': '-0.586', 'Adipocytes (Visceral)': '-0.219', 'Breast glandular cells (progenitors)': '0.255', 'Adipocytes (Breast)': '-0.582', 'Colon enterocytes': '0.001', 'Colon enteroendocrine cells': '0.063', 'Enteric glia cells': '-0.003', 'Mitotic cells (Colon)': '0.124', 'Mitotic cells (Heart)': '0.266', 'Podocytes': '0.155', 'Ascending Loop of Henle cells': '0.238', 'Intercalated cells': '0.175', 'Cholangiocyte': '0.209', 'NK-cells (Liver)': '0.155', 'Respiratory ciliated cells': '0.062', 'Mitotic cells (Lung)': '-0.155', 'NK-cells (Lung)': '0.207', 'B-cells (Lung)': '0.181', 'Alpha cells': '0.151', 'Beta cells': '0.078', 'Prostate glandular cells': '-0.248', 'Prostate basal glandular cells': '-0.302', 'Urothelial cells': '-0.035', 'Keratinocyte (other)': '0.293', 'Keratinocyte (granular)': '-0.201', 'Hair cortex cells': '0.009', 'Inner root sheath cells': '0.045', 'Outer root sheath cells': '0.227', 'Sebaceous gland cells': '-0.182', 'Eccrine sweat gland cells': '0.024', 'Adipocytes (Skin)': '-0.353', 'Mitotic cells (Skin)': '0.228', 'Parietal cells': '-0.389', 'Chief cells': '-0.286', 'Gastric mucous cells': '-0.376', 'Gastric enteroendocrine cells': '-0.226', 'Mitotic cells (Stomach)': '-0.218', 'Parafollicular cells': '0.061', 'Thyroid glandular cells': '0.199', 'Mitotic cells (Thyroid)': '0.089', 'Adrenal cortex cells': '0.195', 'Adrenal medulla cells': '-0.082', 'Mitotic cells (Adrenal gland)': '-0.285', 'Minor salivary glandular cells': '0.119', 'Minor salivary gland ductal cells': '0.196', 'Minor salivary gland basal cells': '0.066', 'Mitotic cells (Minor salivary gland)': '0.005', 'Adipocytes (Minor salivary gland)': '0.142', 'Somatotropes': '-0.397', 'Lactotropes': '-0.214', 'Gonadotropes': '0.124', 'Corticotropes': '-0.144', 'Thyrotropes': '0.078', 'Undifferentiated cells (Pituitary gland)': '0.434', 'Mitotic cells (Spleen)': '-0.011', 'Platelets': '-0.044', 'Erythrocytes': '0.182', 'Hematopoietic stem cells': '-0.023', 'B-cells (Spleen)': '0.020', 'NK-cells (Spleen)': '0.135', 'Amygdala excitatory': '25.3', 'Cerebellar inhibitory': '10.0', 'Cge interneuron': '15.4', 'Deep-layer corticothalamic and 6b': '10.8', 'Deep-layer intratelencephalic': '21.5', 'Deep-layer near-projecting': '4.7', 'Eccentric medium spiny neuron': '7.1', 'Hippocampal ca1-3': '23.0', 'Hippocampal ca4': '23.7', 'Hippocampal dentate gyrus': '44.6', 'Lamp5-lhx6 and chandelier': '6.9', 'Lower rhombic lip': '5.2', 'Mammillary body': '11.2', 'Medium spiny neuron': '2.4', 'Mge interneuron': '10.8', 'Midbrain-derived inhibitory': '27.7', 'Miscellaneous': '15.9', 'Splatter': '8.1', 'Thalamic excitatory': '12.6', 'Upper rhombic lip': '25.2', 'Upper-layer intratelencephalic': '22.6', 'Astrocyte': '239.9', 'Bergmann glia': '59.2', 'Central nervous system macrophage': '120.6', 'Choroid plexus epithelial cell': '1.6', 'Committed oligodendrocyte precursor': '15.5', 'Ependymal cell': '201.8', 'Oligodendrocyte': '15.0', 'Oligodendrocyte precursor cell': '46.1', 'Endothelial cell': '299.8', 'Pericyte': '23.0', 'Vascular associated smooth muscle cell': '260.2', 'Fibroblast': '73.6', 'Leukocyte': '53.9', 'Basophil': '4.5', 'Eosinophil': '0.0', 'Neutrophil': '21.1', 'Classical monocyte': '797.6', 'Non-classical monocyte': '130.4', 'Intermediate monocyte': '137.3', 'T-reg': '77.2', 'GdT-cell': '0.2', 'MAIT T-cell': '200.9', 'Memory CD4 T-cell': '0.2', 'Naive CD4 T-cell': '782.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '878.7', 'Memory B-cell': '0.3', 'Naive B-cell': '803.1', 'Plasmacytoid DC': '8.4', 'Myeloid DC': '120.4', 'NK-cell': '603.5', 'Total PBMC': '39.2', 'Vd2 gdTCR': '97.6', 'Memory CD4 T-cell Th1\\/Th17': '1558.7', 'Memory CD4 T-cell Th17': '1534.0', 'Memory CD4 T-cell Th2': '1452.4', 'Non-Vd2 gdTCR': '66.8', 'Memory CD4 T-cell Th1': '1750.3', 'Memory CD4 T-cell TFH': '1218.0', 'Terminal effector memory CD4 T-cell': '44.4', 'Central memory CD8 T-cell': '133.4', 'Effector memory CD8 T-cell': '104.1', 'Terminal effector memory CD8 T-cell': '87.8', 'Non-switched memory B-cell': '59.4', 'Plasmablast': '65.6', 'Switched memory B-cell': '62.5', 'Exhausted memory B-cell': '62.6', 'Progenitor cell': '20.1', 'Memory T-reg': '1076.2', 'Naive CD4 T-cell activated': '123.6', 'Naive CD8 T-cell activated': '123.4', 'Naive T-reg': '815.9'}
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1A02, 1FOS, 1JNM, 1JUN, 1S9K, 1T2K, 5FV8, 5T01, 6Y3V, 8SOS
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{'Adipose Tissue': 592.2769933554817, 'Adrenal Gland': 92.49251937984496, 'Bladder': 325.8147619047619, 'Blood': 78.36808934337998, 'Blood Vessel': 362.1283520599251, 'Brain': 78.8698080999243, 'Breast': 640.0647494553376, 'Cervix Uteri': 368.7473684210526, 'Colon': 259.33711168164314, 'Esophagus': 193.3527543252595, 'Fallopian Tube': 766.5788888888889, 'Heart': 118.10154587688734, 'Kidney': 116.59786516853931, 'Liver': 145.00733185840707, 'Lung': 455.02927335640135, 'Muscle': 97.86496886674968, 'Nerve': 466.4809369951535, 'Ovary': 455.79633333333334, 'Pancreas': 130.57222560975612, 'Pituitary': 161.5279151943463, 'Prostate': 204.964693877551, 'Salivary Gland': 214.22796296296295, 'Skin': 358.43937534549474, 'Small Intestine': 142.37695187165775, 'Spleen': 75.9851867219917, 'Stomach': 362.629582172702, 'Testis': 51.70360110803324, 'Thyroid': 361.2297549770291, 'Uterus': 361.99133802816897, 'Vagina': 358.2070512820513}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[44.96, 46.45, 59.99, 56.53, 68.37, 64.37, 63.8, 59.85, 57.46, 53.83, 56.81, 53.41, 60.82, 58.3, 53.02, 56.64, 54.87, 52.08, 44.82, 43.95, 41.38, 41.41, 40.29, 38.38, 41.18, 40.06, 39.61, 43.5, 50.21, 45.29, 48.6, 48.1, 54.99, 52.26, 53.65, 54.42, 52.6, 57.1, 61.66, 55.67, 51.4, 65.01, 53.22, 46.63, 50.6, 55.46, 53.94, 48.98, 51.62, 50.16, 54.06, 50.99, 55.07, 45.54, 45.2, 49.71, 42.69, 50.91, 49.57, 51.44, 47.76, 46.17, 39.79, 52.76, 42.87, 57.07, 57.15, 56.95, 53.41, 56.63, 53.81, 55.95, 59.5, 70.8, 66.77, 68.46, 67.03, 71.53, 67.49, 69.07, 70.24, 66.45, 62.83, 61.97, 58.88, 52.62, 53.3, 54.34, 52.88, 49.03, 56.06, 41.54, 57.59, 43.68, 50.87, 55.16, 49.95, 52.78, 48.85, 53.69, 59.5, 56.17, 61.83, 70.75, 71.06, 72.41, 65.56, 66.68, 76.83, 76.5, 79.32, 80.23, 83.83, 88.22, 87.05, 85.54, 85.11, 89.54, 85.56, 88.31, 81.89, 81.12, 76.87, 70.55, 64.0, 57.5, 48.1, 46.64, 35.05, 39.75, 34.59, 40.34, 34.78, 40.44, 38.0, 40.67, 42.04, 38.47, 36.69, 38.21, 37.94, 43.05, 43.69, 47.53, 52.03, 39.7, 45.63, 43.7, 40.23, 45.96, 40.94, 37.42, 38.11, 37.07, 40.22, 41.89, 36.6, 37.57, 34.76, 36.73, 33.36, 40.57, 38.29, 39.6, 35.79, 41.72, 59.85, 60.34, 63.93, 39.32, 48.98, 42.22, 59.47, 54.53, 49.91, 45.47, 54.25, 52.14, 48.46, 50.71, 43.97, 41.42, 39.41, 36.54, 38.36, 32.27, 42.96, 48.33, 38.07, 47.93, 36.74, 31.58, 41.05, 35.56, 43.78, 39.71, 37.06, 48.0, 37.47, 49.47, 42.51, 37.68, 42.78, 39.33, 42.32, 36.39, 48.82, 45.42, 36.8, 42.49, 38.92, 43.4, 42.22, 45.25, 50.23, 44.55, 41.12, 44.59, 40.91, 60.08, 38.86, 39.01, 50.44, 47.29, 45.19, 51.51, 43.54, 46.48, 52.71, 42.85, 40.81, 41.55, 54.66, 48.28, 37.6, 43.76, 39.76, 44.59, 48.08, 51.47, 50.22, 54.23, 51.23, 56.3, 62.65, 74.29, 76.97, 78.54, 83.57, 84.63, 88.32, 91.34, 88.06, 93.18, 94.21, 94.98, 95.05, 95.92, 96.31, 95.59, 96.8, 97.59, 97.53, 97.07, 98.06, 98.14, 97.28, 98.37, 98.32, 98.1, 98.36, 98.37, 98.48, 98.03, 98.37, 98.4, 98.02, 98.43, 98.48, 98.65, 98.57, 98.62, 98.48, 98.76, 98.59, 98.58, 98.43, 98.58, 98.47, 98.46, 98.43, 98.3, 98.34, 98.41, 98.45, 98.22, 98.25, 98.27, 98.1, 98.24, 98.39, 98.12, 97.83, 97.83, 97.81, 97.15, 97.25, 96.28, 94.98, 94.54, 93.63, 92.36, 90.56, 92.82, 92.03, 90.22, 90.41, 90.92, 83.61, 81.65, 74.21, 66.21, 57.27, 58.19, 49.06, 53.54, 51.25, 55.93, 44.61, 34.83, 40.72]
|
[0.99, 0.93, 0.93, 0.94, 0.91, 0.91, 0.9, 0.72, 0.95, 0.85, 0.71, 0.75, 0.64, 0.71, 0.65, 0.66, 0.76, 0.82, 0.77, 0.9, 0.92, 0.95, 0.96, 1.0, 1.0, 1.0, 0.97, 1.0, 0.95, 0.99, 1.0, 0.93, 0.89, 0.95, 0.84, 0.93, 0.7, 0.92, 0.65, 0.84, 0.76, 0.81, 0.8, 0.85, 0.99, 0.82, 0.97, 0.96, 0.99, 0.93, 0.86, 0.93, 0.96, 0.93, 0.94, 1.0, 0.97, 0.97, 0.99, 0.9, 0.97, 0.92, 0.76, 0.97, 0.66, 0.71, 0.92, 0.81, 0.66, 0.94, 0.36, 0.75, 0.89, 0.59, 0.59, 0.47, 0.63, 0.7, 0.54, 0.56, 0.53, 0.52, 0.61, 0.71, 0.75, 0.81, 0.87, 0.65, 0.94, 0.98, 0.8, 0.98, 0.78, 0.86, 0.83, 0.94, 0.84, 0.89, 0.86, 0.64, 0.93, 0.76, 0.59, 0.57, 0.75, 0.79, 0.58, 0.55, 0.51, 0.83, 0.41, 0.59, 0.54, 0.69, 0.63, 0.7, 0.49, 0.42, 0.54, 0.63, 0.55, 0.66, 0.49, 0.72, 0.81, 0.72, 0.8, 0.73, 0.93, 0.78, 0.96, 0.95, 0.95, 0.94, 0.97, 0.99, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.94, 0.88, 0.84, 0.91, 0.82, 0.91, 0.79, 0.86, 0.8, 0.71, 0.88, 0.85, 0.6, 0.83, 0.84, 0.8, 0.85, 0.82, 0.93, 0.73, 0.9, 0.98, 0.92, 0.98, 1.0, 0.97, 0.96, 0.96, 0.86, 0.92, 0.95, 0.81, 0.98, 0.9, 1.0, 0.96, 0.95, 0.97, 0.95, 0.94, 1.0, 0.99, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.98, 0.98, 1.0, 0.91, 0.87, 0.91, 0.89, 0.91, 0.83, 0.99, 0.76, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.94, 0.9, 0.94, 0.91, 0.83, 0.85, 0.88, 0.76, 0.93, 0.54, 0.51, 0.58, 0.58, 0.3, 0.3, 0.61, 0.7, 0.62, 0.57, 0.35, 0.44, 0.63, 0.68, 0.59, 0.58, 0.6, 0.66, 0.68, 0.59, 0.5, 0.39, 0.54, 0.55, 0.61, 0.72, 0.63, 0.58, 0.69, 0.65, 0.38, 0.68, 0.39, 0.46, 0.63, 0.49, 0.61, 0.65, 0.61, 0.5, 0.75, 0.48, 0.52, 0.67, 0.55, 0.48, 0.65, 0.59, 0.67, 0.66, 0.38, 0.61, 0.49, 0.34, 0.53, 0.58, 0.55, 0.65, 0.54, 0.52, 0.51, 0.53, 0.48, 0.62, 0.66, 0.57, 0.66, 0.44, 0.56, 0.48, 0.41, 0.51, 0.7, 0.75, 0.78, 0.4, 0.87, 0.42, 0.74, 0.89, 0.69, 0.94, 0.89, 0.97, 0.93, 0.9, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 61.072749
| 0.791057
| 2,189
|
O43791
|
P06401
|
26693071
|
UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
PGR
|
MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
|
Homo sapiens
|
Nucleus, Cytoplasm, Nucleus, Cytoplasm, Mitochondrion outer membrane
|
Group enriched (cervix, endometrium, fallopian tube, smooth muscle)
|
{'Ciliated cells': '54.3', 'Basal respiratory cells': '0.0', 'Club cells': '0.3', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.7', 'Serous glandular cells': '4.5', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.1', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.1', 'Exocrine glandular cells': '-0.206', 'Basal prostatic cells': '2.1', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.692', 'Breast myoepithelial cells': '0.565', 'Glandular and luminal cells': '74.1', 'Secretory cells': '99.2', 'Basal keratinocytes': '0.0', 'Suprabasal keratinocytes': '0.0', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '0.145', 'Alveolar cells type 2': '-0.604', 'Salivary duct cells': '0.7', 'Ductal cells': '0.333', 'Hepatocytes': '0.144', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.010', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.397', 'Sertoli cells': '-0.330', 'Granulosa cells': '11.8', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.036', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.9', 'Horizontal cells': '1.9', 'Astrocytes': '0.3', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.3', 'Microglial cells': '21.5', 'Muller glia cells': '0.6', 'Schwann cells': '0.008', 'Spermatogonia': '-0.060', 'Spermatocytes': '-0.066', 'Early spermatids': '0.354', 'Late spermatids': '0.122', 'Oocytes': '8.1', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '2.2', 'Lymphatic endothelial cells': '7.1', 'Cardiomyocytes': '0.704', 'Skeletal myocytes': '0.247', 'Smooth muscle cells': '21.5', 'Adipocytes': '1.4', 'Melanocytes': '-0.012', 'Fibroblasts': '27.1', 'Peritubular cells': '0.270', 'Endometrial stromal cells': '163.3', 'Ovarian stromal cells': '22.3', 'Undifferentiated cells': '0.0', 'T-cells': '2.2', 'B-cells': '0.7', 'Plasma cells': '7.1', 'Nk-cells': '0.0', 'Granulocytes': '5.7', 'Monocytes': '0.0', 'Macrophages': '1.7', 'Hofbauer cells': '0.2', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.105', 'Erythroid cells': '0.096', 'Adipocytes (Subcutaneous)': '-0.432', 'Adipocytes (Visceral)': '-0.428', 'Breast glandular cells (progenitors)': '0.431', 'Adipocytes (Breast)': '-0.458', 'Colon enterocytes': '-0.148', 'Colon enteroendocrine cells': '0.200', 'Enteric glia cells': '-0.042', 'Mitotic cells (Colon)': '-0.181', 'Mitotic cells (Heart)': '0.419', 'Podocytes': '0.231', 'Ascending Loop of Henle cells': '0.366', 'Intercalated cells': '0.241', 'Cholangiocyte': '0.332', 'NK-cells (Liver)': '0.075', 'Respiratory ciliated cells': '0.132', 'Mitotic cells (Lung)': '-0.196', 'NK-cells (Lung)': '0.479', 'B-cells (Lung)': '0.271', 'Alpha cells': '0.604', 'Beta cells': '0.377', 'Prostate glandular cells': '-0.440', 'Prostate basal glandular cells': '-0.116', 'Urothelial cells': '0.037', 'Keratinocyte (other)': '-0.302', 'Keratinocyte (granular)': '-0.395', 'Hair cortex cells': '0.333', 'Inner root sheath cells': '0.314', 'Outer root sheath cells': '0.515', 'Sebaceous gland cells': '0.112', 'Eccrine sweat gland cells': '0.510', 'Adipocytes (Skin)': '0.309', 'Mitotic cells (Skin)': '0.160', 'Parietal cells': '-0.683', 'Chief cells': '-0.576', 'Gastric mucous cells': '-0.664', 'Gastric enteroendocrine cells': '-0.450', 'Mitotic cells (Stomach)': '-0.293', 'Parafollicular cells': '-0.042', 'Thyroid glandular cells': '-0.007', 'Mitotic cells (Thyroid)': '0.174', 'Adrenal cortex cells': '0.336', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '0.225', 'Minor salivary glandular cells': '0.400', 'Minor salivary gland ductal cells': '0.283', 'Minor salivary gland basal cells': '-0.352', 'Mitotic cells (Minor salivary gland)': '-0.300', 'Adipocytes (Minor salivary gland)': '0.024', 'Somatotropes': '-0.071', 'Lactotropes': '0.026', 'Gonadotropes': '0.557', 'Corticotropes': '-0.110', 'Thyrotropes': '0.186', 'Undifferentiated cells (Pituitary gland)': '0.077', 'Mitotic cells (Spleen)': '-0.210', 'Platelets': '-0.230', 'Erythrocytes': '-0.039', 'Hematopoietic stem cells': '-0.243', 'B-cells (Spleen)': '0.136', 'NK-cells (Spleen)': '0.271', 'Amygdala excitatory': '1.5', 'Cerebellar inhibitory': '2.2', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.2', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.1', 'Hippocampal ca1-3': '0.3', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.2', 'Lower rhombic lip': '0.5', 'Mammillary body': '1.1', 'Medium spiny neuron': '0.3', 'Mge interneuron': '0.4', 'Midbrain-derived inhibitory': '0.2', 'Miscellaneous': '0.2', 'Splatter': '9.8', 'Thalamic excitatory': '0.3', 'Upper rhombic lip': '0.6', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '3.2', 'Bergmann glia': '0.2', 'Central nervous system macrophage': '0.3', 'Choroid plexus epithelial cell': '2.2', 'Committed oligodendrocyte precursor': '0.9', 'Ependymal cell': '32.7', 'Oligodendrocyte': '0.3', 'Oligodendrocyte precursor cell': '6.1', 'Endothelial cell': '121.0', 'Pericyte': '55.4', 'Vascular associated smooth muscle cell': '37.6', 'Fibroblast': '83.6', 'Leukocyte': '0.6', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
|
1A28, 1E3K, 1SQN, 1SR7, 1ZUC, 2C7A, 2OVH, 2OVM, 2W8Y, 3D90, 3G8O, 3HQ5, 3KBA, 3ZR7, 3ZRA, 3ZRB, 4A2J, 4APU, 4OAR, 5CC0
|
{'Adipose Tissue': 2.5042970930232555, 'Adrenal Gland': 1.85278992248062, 'Bladder': 3.8976, 'Blood': 0.00970236598493, 'Blood Vessel': 13.78215902621723, 'Brain': 0.4638034140802422, 'Breast': 7.605907189542483, 'Cervix Uteri': 107.6032105263158, 'Colon': 3.912380077021823, 'Esophagus': 2.6752016955017304, 'Fallopian Tube': 45.83111111111111, 'Heart': 2.160741846689896, 'Kidney': 1.0471730337078653, 'Liver': 0.1735477433628318, 'Lung': 3.3827740484429065, 'Muscle': 0.5750552677459527, 'Nerve': 2.6406570274636514, 'Ovary': 21.89036666666667, 'Pancreas': 0.218764481707317, 'Pituitary': 2.546843109540636, 'Prostate': 6.771152244897959, 'Salivary Gland': 0.9861524074074074, 'Skin': 0.6583324499723604, 'Small Intestine': 1.5447322994652406, 'Spleen': 1.8593120331950208, 'Stomach': 1.2920202228412256, 'Testis': 2.2379252077562324, 'Thyroid': 1.4827085911179172, 'Uterus': 104.8494295774648, 'Vagina': 26.589916666666667}
|
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1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 0.99, 0.99, 0.97, 0.95, 0.89, 0.96, 0.83, 0.99, 0.94, 0.8, 0.97, 1.0, 0.95, 1.0, 0.88, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 0.98, 0.98, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 0.97, 0.99, 0.96, 0.97, 1.0, 0.94, 1.0, 0.97, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.96, 0.98, 0.94, 0.94, 0.79, 0.86, 0.84, 0.83, 0.69, 0.92, 0.76, 0.73, 0.97, 0.79, 0.89, 0.77, 0.96, 0.95, 0.96, 0.95, 0.95, 0.98, 0.73, 0.98, 0.94, 0.94, 0.92, 0.89, 0.87, 0.91, 0.95, 1.0, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 1.0, 0.98, 1.0, 0.89, 0.99, 0.93, 0.9, 0.97, 0.98, 0.95, 0.98, 0.91, 0.93, 0.78, 0.86, 0.87, 0.85, 0.94, 0.66, 0.99, 0.94, 0.99, 0.77, 0.9, 0.98, 0.78, 0.95, 0.86, 0.94, 0.98, 0.9, 0.87, 0.95, 0.94, 0.88, 0.96, 0.92, 0.89, 0.87, 0.88, 0.99, 1.0, 1.0, 0.97, 0.96, 0.91, 0.97, 0.95, 0.86, 0.98, 0.92, 0.88, 0.85, 0.83, 0.85, 0.56, 0.55, 0.02, 0.6, 0.0, 0.02, 0.6, 0.13, 0.82, 0.13, 0.57, 0.27, 0.66, 0.16, 0.27, 0.73, 0.03, 0.31, 0.0, 0.01, 0.36, 0.39, 0.0, 0.41, 0.48, 0.15, 0.0, 0.44, 0.65, 0.05, 0.44, 0.6, 0.46, 0.71, 0.42, 0.81, 0.35, 0.84, 0.22, 0.97, 0.48, 0.86, 0.47, 0.69, 0.36, 0.57, 0.1, 0.25, 0.57, 0.84, 0.45, 0.15, 0.89, 0.75, 0.08, 0.3, 0.06, 0.05, 0.06, 0.17, 0.36, 0.32, 0.0, 0.46, 0.47, 0.4, 0.46, 0.04, 0.64, 0.32, 0.85, 0.98, 0.9, 0.93, 0.7, 0.92, 0.98, 0.61, 1.0, 0.87, 0.72, 0.84, 0.89, 0.83, 0.81, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.89, 1.0, 0.86, 1.0, 1.0, 0.97, 0.99, 0.87, 0.95, 0.76, 0.9, 0.81, 0.91, 0.95, 0.89, 0.9, 0.89, 0.75, 0.82, 0.77, 0.47, 0.16, 0.77, 0.19, 0.0, 0.56, 0.36, 0.01, 0.28, 0.71, 0.2, 0.38, 0.45, 0.88, 0.66, 0.23, 0.6, 0.0, 0.7, 0.11, 0.4, 0.5, 0.88, 0.7, 0.81, 0.34, 0.48, 0.38, 0.25, 0.36, 0.04, 0.11, 0.11, 0.12, 0.18, 0.12, 0.3, 0.03, 0.07, 0.25, 0.34, 0.12, 0.02, 0.42, 0.27, 0.11, 0.02, 0.75, 0.02, 0.0, 0.11, 0.37, 0.03, 0.4, 0.3, 0.0, 0.5, 0.62, 0.05, 0.41, 0.24, 0.25, 0.03, 0.06, 0.07, 0.23, 0.02, 0.02, 0.04, 0.09, 0.01, 0.03, 0.18, 0.11, 0.05, 0.11, 0.04, 0.0, 0.15, 0.03, 0.01, 0.11, 0.23, 0.0, 0.25, 0.59, 0.63, 0.16, 0.54, 0.0, 0.69, 0.36, 0.01, 0.13, 0.09, 0.01, 0.31, 0.19, 0.0, 0.35, 0.01, 0.42, 0.48, 0.56, 0.22, 0.0, 0.47, 0.61, 0.07, 0.54, 0.05, 0.34, 0.68, 0.09, 0.0, 0.35, 0.27, 0.07, 0.21, 0.6, 0.04, 0.0, 0.42, 0.31, 0.0, 0.38, 0.69, 0.15, 0.6, 0.04, 0.11, 0.43, 0.25, 0.0, 0.02, 0.04, 0.01, 0.0, 0.09, 0.0, 0.0, 0.03, 0.0, 0.0, 0.01, 0.13, 0.06, 0.15, 0.55, 0.8, 0.35, 0.12, 0.69, 0.12, 0.31, 0.67, 0.41, 0.01, 0.52, 0.64, 0.04, 0.11, 0.31, 0.34, 0.01, 0.23, 0.54, 0.14, 0.0, 0.49, 0.49, 0.01, 0.01, 0.49, 0.53, 0.55, 0.28, 0.71, 0.41, 0.8, 0.79, 0.41, 0.22, 0.57, 0.57, 0.06, 0.22, 0.47, 0.36, 0.0, 0.0, 0.43, 0.09, 0.0, 0.09, 0.55, 0.05, 0.16, 0.48, 0.12, 0.05, 0.55, 0.46, 0.1, 0.03, 0.5, 0.27, 0.12, 0.14, 0.46, 0.05, 0.22, 0.63, 0.54, 0.22, 0.95, 0.85, 0.42, 0.62, 0.06, 0.64, 0.19, 0.17, 0.55, 0.06, 0.02, 0.21, 0.15, 0.04, 0.0, 0.24, 0.24, 0.05, 0.0, 0.35, 0.34, 0.14, 0.25, 0.69, 0.4, 0.47, 0.15, 0.53, 0.48, 0.18, 0.35, 0.26, 0.3, 0.95, 0.71]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 56.239807
| 0.720407
| 587
|
O43791
|
P08151
|
nan, 22199232, hUbiquitome
|
degron_data, UbiNet, UbiBrowser, 31181401
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
GLI1
|
MFNSMTPPPISSYGEPCCLRPLPSQGAPSVGTEGLSGPPFCHQANLMSGPHSYGPARETNSCTEGPLFSSPRSAVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFINSRCTSPGGSYGHLSIGTMSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSARGGMIPHPQSRGPFPTCQLKSELDMLVGKCREEPLEGDMSSPNSTGIQDPLLGMLDGREDLEREEKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAPSISTVEPKREREGGPIREESRLTVPEGAMKPQPSPGAQSSCSSDHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEGPCIAGTGLSTLRRLENLRLDQLHQLRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASSLDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPTVAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMDFPPTDTLGYGGPEGAAAEPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALGGTYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQELLWEGGGREDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSGSYPTPSPCHENFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLGGGPALYPPPEGQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGPPNMAVGNMSVLLRSLPGETEFLNSSA
|
Homo sapiens
|
Cytoplasm, Nucleus, Cytoplasm, Nucleus
|
Tissue enhanced (cervix)
|
{'Ciliated cells': '0.1', 'Basal respiratory cells': '0.4', 'Club cells': '0.1', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.3', 'Serous glandular cells': '0.4', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.1', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.2', 'Exocrine glandular cells': '-0.178', 'Basal prostatic cells': '0.4', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.292', 'Breast myoepithelial cells': '0.335', 'Glandular and luminal cells': '0.2', 'Secretory cells': '0.3', 'Basal keratinocytes': '0.9', 'Suprabasal keratinocytes': '0.1', 'Basal squamous epithelial cells': '0.4', 'Squamous epithelial cells': '0.3', 'Alveolar cells type 1': '-0.188', 'Alveolar cells type 2': '-0.290', 'Salivary duct cells': '0.3', 'Ductal cells': '0.510', 'Hepatocytes': '-0.084', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.037', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.164', 'Sertoli cells': '0.492', 'Granulosa cells': '0.5', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.509', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.5', 'Horizontal cells': '0.0', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.3', 'Schwann cells': '0.059', 'Spermatogonia': '0.203', 'Spermatocytes': '-0.148', 'Early spermatids': '-0.505', 'Late spermatids': '-0.572', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.1', 'Extravillous trophoblasts': '0.1', 'Endothelial cells': '0.5', 'Lymphatic endothelial cells': '3.0', 'Cardiomyocytes': '-0.021', 'Skeletal myocytes': '0.402', 'Smooth muscle cells': '1.7', 'Adipocytes': '0.6', 'Melanocytes': '0.105', 'Fibroblasts': '5.0', 'Peritubular cells': '0.692', 'Endometrial stromal cells': '5.1', 'Ovarian stromal cells': '2.1', 'Undifferentiated cells': '0.3', 'T-cells': '0.8', 'B-cells': '1.5', 'Plasma cells': '0.3', 'Nk-cells': '0.3', 'Granulocytes': '0.2', 'Monocytes': '0.4', 'Macrophages': '0.5', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.2', 'Dendritic cells': '0.0', 'Langerhans cells': '0.029', 'Erythroid cells': '-0.047', 'Adipocytes (Subcutaneous)': '-0.277', 'Adipocytes (Visceral)': '-0.152', 'Breast glandular cells (progenitors)': '0.233', 'Adipocytes (Breast)': '-0.227', 'Colon enterocytes': '0.160', 'Colon enteroendocrine cells': '0.206', 'Enteric glia cells': '0.230', 'Mitotic cells (Colon)': '0.101', 'Mitotic cells (Heart)': '0.195', 'Podocytes': '-0.238', 'Ascending Loop of Henle cells': '0.376', 'Intercalated cells': '0.025', 'Cholangiocyte': '0.333', 'NK-cells (Liver)': '-0.002', 'Respiratory ciliated cells': '0.173', 'Mitotic cells (Lung)': '0.125', 'NK-cells (Lung)': '0.088', 'B-cells (Lung)': '0.171', 'Alpha cells': '0.273', 'Beta cells': '0.100', 'Prostate glandular cells': '0.006', 'Prostate basal glandular cells': '0.182', 'Urothelial cells': '0.201', 'Keratinocyte (other)': '-0.395', 'Keratinocyte (granular)': '-0.421', 'Hair cortex cells': '0.440', 'Inner root sheath cells': '0.483', 'Outer root sheath cells': '0.677', 'Sebaceous gland cells': '0.241', 'Eccrine sweat gland cells': '0.313', 'Adipocytes (Skin)': '0.290', 'Mitotic cells (Skin)': '0.212', 'Parietal cells': '-0.087', 'Chief cells': '-0.062', 'Gastric mucous cells': '0.010', 'Gastric enteroendocrine cells': '0.065', 'Mitotic cells (Stomach)': '-0.025', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.202', 'Mitotic cells (Thyroid)': '0.119', 'Adrenal cortex cells': '0.399', 'Adrenal medulla cells': '-0.116', 'Mitotic cells (Adrenal gland)': '0.095', 'Minor salivary glandular cells': '-0.041', 'Minor salivary gland ductal cells': '0.060', 'Minor salivary gland basal cells': '-0.013', 'Mitotic cells (Minor salivary gland)': '0.029', 'Adipocytes (Minor salivary gland)': '0.074', 'Somatotropes': '-0.423', 'Lactotropes': '-0.067', 'Gonadotropes': '0.352', 'Corticotropes': '-0.039', 'Thyrotropes': '0.189', 'Undifferentiated cells (Pituitary gland)': '0.382', 'Mitotic cells (Spleen)': '0.165', 'Platelets': '0.206', 'Erythrocytes': '0.086', 'Hematopoietic stem cells': '0.080', 'B-cells (Spleen)': '0.249', 'NK-cells (Spleen)': '0.066', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.1', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.1', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.1', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.1', 'Splatter': '0.0', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.2', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '7.3', 'Bergmann glia': '41.3', 'Central nervous system macrophage': '0.7', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.1', 'Oligodendrocyte': '0.0', 'Oligodendrocyte precursor cell': '0.1', 'Endothelial cell': '0.2', 'Pericyte': '0.9', 'Vascular associated smooth muscle cell': '0.2', 'Fibroblast': '4.5', 'Leukocyte': '0.9', 'Basophil': '1.0', 'Eosinophil': '0.3', 'Neutrophil': '6.9', 'Classical monocyte': '1.0', 'Non-classical monocyte': '0.5', 'Intermediate monocyte': '0.8', 'T-reg': '1.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '2.2', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '2.8', 'Memory B-cell': '0.3', 'Naive B-cell': '6.6', 'Plasmacytoid DC': '0.9', 'Myeloid DC': '0.8', 'NK-cell': '6.4', 'Total PBMC': '0.8', 'Vd2 gdTCR': '1.1', 'Memory CD4 T-cell Th1\\/Th17': '1.3', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '2.0', 'Non-Vd2 gdTCR': '1.4', 'Memory CD4 T-cell Th1': '2.0', 'Memory CD4 T-cell TFH': '1.6', 'Terminal effector memory CD4 T-cell': '2.4', 'Central memory CD8 T-cell': '1.3', 'Effector memory CD8 T-cell': '0.8', 'Terminal effector memory CD8 T-cell': '1.6', 'Non-switched memory B-cell': '2.9', 'Plasmablast': '0.0', 'Switched memory B-cell': '1.0', 'Exhausted memory B-cell': '1.6', 'Progenitor cell': '1.0', 'Memory T-reg': '2.7', 'Naive CD4 T-cell activated': '3.4', 'Naive CD8 T-cell activated': '4.7', 'Naive T-reg': '2.4'}
|
2GLI, 4BLB, 4KMD, 5OM0, 7T91
|
{'Adipose Tissue': 2.988595456810631, 'Adrenal Gland': 1.7361617054263565, 'Bladder': 8.863676190476191, 'Blood': 1.347432292787944, 'Blood Vessel': 3.133266441947566, 'Brain': 1.4756066953065858, 'Breast': 3.0570320479302833, 'Cervix Uteri': 16.62008947368421, 'Colon': 3.1243742747111685, 'Esophagus': 1.3236616892733564, 'Fallopian Tube': 4.539666666666666, 'Heart': 1.226563101045296, 'Kidney': 1.764883595505618, 'Liver': 0.5306526548672567, 'Lung': 3.4192273356401386, 'Muscle': 0.508932899128269, 'Nerve': 49.39320032310177, 'Ovary': 3.4426566666666663, 'Pancreas': 0.576325756097561, 'Pituitary': 1.947369893992933, 'Prostate': 8.470241632653062, 'Salivary Gland': 1.095639197530864, 'Skin': 2.16994954671089, 'Small Intestine': 5.408090909090909, 'Spleen': 1.7625759336099585, 'Stomach': 2.4367554317548747, 'Testis': 11.764969529085874, 'Thyroid': 5.431041653905054, 'Uterus': 9.447659929577464, 'Vagina': 7.076092756410257}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[38.13, 42.92, 41.92, 39.54, 49.01, 60.2, 60.2, 48.53, 46.57, 47.6, 37.08, 37.66, 41.58, 42.35, 43.75, 44.07, 41.57, 44.36, 40.47, 40.29, 42.57, 37.28, 54.65, 39.96, 40.72, 39.56, 41.96, 44.72, 39.08, 39.47, 38.16, 38.36, 35.89, 36.16, 38.21, 37.76, 35.94, 38.48, 41.49, 33.68, 32.31, 37.73, 34.28, 38.64, 34.19, 37.88, 36.52, 36.13, 36.37, 44.9, 37.77, 33.09, 38.71, 33.71, 46.14, 36.13, 36.83, 35.27, 35.43, 36.87, 34.48, 34.17, 35.93, 34.24, 38.08, 44.17, 35.4, 33.25, 34.71, 34.98, 33.64, 33.81, 33.23, 30.54, 35.77, 31.18, 36.16, 29.92, 30.95, 28.28, 28.41, 27.11, 34.82, 26.93, 30.91, 36.29, 30.99, 33.94, 30.1, 30.25, 32.43, 36.09, 50.45, 62.29, 66.28, 66.62, 68.55, 64.25, 67.14, 66.82, 65.26, 64.4, 63.57, 60.19, 62.9, 60.46, 64.1, 60.99, 64.02, 60.36, 54.92, 57.09, 49.7, 37.94, 38.46, 34.82, 40.45, 32.22, 31.65, 37.88, 32.58, 38.93, 42.11, 36.82, 36.98, 35.79, 37.42, 37.94, 38.4, 37.65, 43.81, 37.41, 37.49, 43.76, 33.86, 48.92, 34.4, 39.12, 32.68, 30.66, 34.61, 32.59, 33.4, 33.86, 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1.0, 1.0, 1.0, 0.97, 0.26, 0.63, 0.8, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.97, 1.0, 1.0, 0.92, 0.97, 0.84, 0.65, 0.88, 0.65, 0.75, 0.88, 0.87, 0.99, 0.95, 0.99, 1.0, 0.96, 1.0, 0.99, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 45.309656
| 0.82585
| 407
|
O43791
|
P10070
|
nan, 22199232, UNIPROT
|
degron_data, UbiNet, UbiBrowser, 31181401
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
GLI2
|
METSASATASEKQEAKSGILEAAGFPDPGKKASPLVVAAAAAAAVAAQGVPQHLLPPFHAPLPIDMRHQEGRYHYEPHSVHGVHGPPALSGSPVISDISLIRLSPHPAGPGESPFNAPHPYVNPHMEHYLRSVHSSPTLSMISAARGLSPADVAQEHLKERGLFGLPAPGTTPSDYYHQMTLVAGHPAPYGDLLMQSGGAASAPHLHDYLNPVDVSRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQSSESAVSSTVNPVAIHKRSKVKTEPEGLRPASPLALTQGQVSGHGSCGCALPLSQEQLADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAPSAGGLQLRKHMTTMHRFEQLKKEKLKSLKDSCSWAGPTPHTRNTKLPPLPGSGSILENFSGSGGGGPAGLLPNPRLSELSASEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGGSGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERMSLRTRLALLDAPERTLPAGCPRPLGPRRGSDGPTYGHGHAGAAPAFPHEAPGGGARRASDPVRRPDALSLPRVQRFHSTHNVNPGPLPPCADRRGLRLQSHPSTDGGLARGAYSPRPPSISENVAMEAVAAGVDGAGPEADLGLPEDDLVLPDDVVQYIKAHASGALDEGTGQVYPTESTGFSDNPRLPSPGLHGQRRMVAADSNVGPSAPMLGGCQLGFGAPSSLNKNNMPVQWNEVSSGTVDALASQVKPPPFPQGNLAVVQQKPAFGQYPGYSPQGLQASPGGLDSTQPHLQPRSGAPSQGIPRVNYMQQLRQPVAGSQCPGMTTTMSPHACYGQVHPQLSPSTISGALNQFPQSCSNMPAKPGHLGHPQQTEVAPDPTTMGNRHRELGVPDSALAGVPPPHPVQSYPQQSHHLAASMSQEGYHQVPSLLPARQPGFMEPQTGPMGVATAGFGLVQPRPPLEPSPTGRHRGVRAVQQQLAYARATGHAMAAMPSSQETAEAVPKGAMGNMGSVPPQPPPQDAGGAPDHSMLYYYGQIHMYEQDGGLENLGSCQVMRSQPPQPQACQDSIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPSLLHSLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEESKFLNMMT
|
Homo sapiens
|
Nucleus, Cytoplasm, Cell projection, cilium, Nucleus, Nucleus
|
Tissue enhanced (ovary)
|
{'Ciliated cells': '0.3', 'Basal respiratory cells': '0.4', 'Club cells': '1.6', 'Ionocytes': '0.7', 'Mucus glandular cells': '0.4', 'Serous glandular cells': '0.4', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.316', 'Basal prostatic cells': '0.1', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.472', 'Breast myoepithelial cells': '0.559', 'Glandular and luminal cells': '0.9', 'Secretory cells': '0.4', 'Basal keratinocytes': '2.5', 'Suprabasal keratinocytes': '1.3', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '-0.165', 'Alveolar cells type 2': '-0.373', 'Salivary duct cells': '0.1', 'Ductal cells': '0.421', 'Hepatocytes': '0.017', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.086', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.607', 'Sertoli cells': '0.548', 'Granulosa cells': '1.1', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.590', 'Excitatory neurons': '0.6', 'Inhibitory neurons': '1.6', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '37.5', 'Oligodendrocyte precursor cells': '2.8', 'Oligodendrocytes': '0.3', 'Microglial cells': '2.7', 'Muller glia cells': '0.0', 'Schwann cells': '0.263', 'Spermatogonia': '0.320', 'Spermatocytes': '-0.115', 'Early spermatids': '-0.590', 'Late spermatids': '-0.599', 'Oocytes': '0.7', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.1', 'Extravillous trophoblasts': '0.1', 'Endothelial cells': '0.4', 'Lymphatic endothelial cells': '2.8', 'Cardiomyocytes': '0.007', 'Skeletal myocytes': '0.279', 'Smooth muscle cells': '3.1', 'Adipocytes': '0.3', 'Melanocytes': '0.125', 'Fibroblasts': '8.2', 'Peritubular cells': '0.642', 'Endometrial stromal cells': '5.7', 'Ovarian stromal cells': '11.7', 'Undifferentiated cells': '0.1', 'T-cells': '0.1', 'B-cells': '0.1', 'Plasma cells': '0.1', 'Nk-cells': '0.4', 'Granulocytes': '0.2', 'Monocytes': '0.0', 'Macrophages': '0.2', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.118', 'Erythroid cells': '0.210', 'Adipocytes (Subcutaneous)': '-0.518', 'Adipocytes (Visceral)': '-0.439', 'Breast glandular cells (progenitors)': '0.442', 'Adipocytes (Breast)': '-0.472', 'Colon enterocytes': '-0.062', 'Colon enteroendocrine cells': '0.358', 'Enteric glia cells': '0.271', 'Mitotic cells (Colon)': '-0.208', 'Mitotic cells (Heart)': '0.341', 'Podocytes': '-0.262', 'Ascending Loop of Henle cells': '0.411', 'Intercalated cells': '-0.149', 'Cholangiocyte': '0.473', 'NK-cells (Liver)': '0.014', 'Respiratory ciliated cells': '0.011', 'Mitotic cells (Lung)': '0.079', 'NK-cells (Lung)': '0.132', 'B-cells (Lung)': '0.175', 'Alpha cells': '0.344', 'Beta cells': '0.125', 'Prostate glandular cells': '-0.500', 'Prostate basal glandular cells': '-0.327', 'Urothelial cells': '-0.093', 'Keratinocyte (other)': '-0.086', 'Keratinocyte (granular)': '-0.357', 'Hair cortex cells': '0.285', 'Inner root sheath cells': '0.339', 'Outer root sheath cells': '0.651', 'Sebaceous gland cells': '0.215', 'Eccrine sweat gland cells': '0.181', 'Adipocytes (Skin)': '0.036', 'Mitotic cells (Skin)': '0.279', 'Parietal cells': '-0.700', 'Chief cells': '-0.601', 'Gastric mucous cells': '-0.563', 'Gastric enteroendocrine cells': '-0.417', 'Mitotic cells (Stomach)': '-0.175', 'Parafollicular cells': '-0.021', 'Thyroid glandular cells': '0.031', 'Mitotic cells (Thyroid)': '0.189', 'Adrenal cortex cells': '0.153', 'Adrenal medulla cells': '0.102', 'Mitotic cells (Adrenal gland)': '0.206', 'Minor salivary glandular cells': '0.489', 'Minor salivary gland ductal cells': '0.332', 'Minor salivary gland basal cells': '-0.285', 'Mitotic cells (Minor salivary gland)': '-0.387', 'Adipocytes (Minor salivary gland)': '-0.021', 'Somatotropes': '0.378', 'Lactotropes': '0.230', 'Gonadotropes': '0.432', 'Corticotropes': '-0.284', 'Thyrotropes': '-0.080', 'Undifferentiated cells (Pituitary gland)': '-0.030', 'Mitotic cells (Spleen)': '-0.162', 'Platelets': '-0.064', 'Erythrocytes': '0.123', 'Hematopoietic stem cells': '-0.140', 'B-cells (Spleen)': '0.019', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '0.6', 'Cerebellar inhibitory': '0.9', 'Cge interneuron': '1.2', 'Deep-layer corticothalamic and 6b': '0.6', 'Deep-layer intratelencephalic': '0.8', 'Deep-layer near-projecting': '0.4', 'Eccentric medium spiny neuron': '1.5', 'Hippocampal ca1-3': '0.6', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '1.4', 'Lamp5-lhx6 and chandelier': '1.4', 'Lower rhombic lip': '1.0', 'Mammillary body': '0.7', 'Medium spiny neuron': '0.5', 'Mge interneuron': '2.6', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '0.4', 'Splatter': '1.7', 'Thalamic excitatory': '1.1', 'Upper rhombic lip': '1.4', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '104.4', 'Bergmann glia': '181.7', 'Central nervous system macrophage': '0.6', 'Choroid plexus epithelial cell': '21.9', 'Committed oligodendrocyte precursor': '1.8', 'Ependymal cell': '65.9', 'Oligodendrocyte': '0.6', 'Oligodendrocyte precursor cell': '7.9', 'Endothelial cell': '1.2', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '16.1', 'Fibroblast': '57.7', 'Leukocyte': '1.0', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
| null |
{'Adipose Tissue': 2.957906146179402, 'Adrenal Gland': 1.614758527131783, 'Bladder': 6.168333333333333, 'Blood': 0.0126402002152852, 'Blood Vessel': 6.23919925093633, 'Brain': 0.936468508705526, 'Breast': 3.165194553376906, 'Cervix Uteri': 10.257747368421052, 'Colon': 5.3193181001283705, 'Esophagus': 5.281566546712803, 'Fallopian Tube': 7.028666666666666, 'Heart': 1.5057557259001162, 'Kidney': 1.2827726966292134, 'Liver': 0.3448717654867256, 'Lung': 4.621348961937716, 'Muscle': 0.5914638356164383, 'Nerve': 6.9068158319870765, 'Ovary': 24.872172222222225, 'Pancreas': 0.2932526829268292, 'Pituitary': 3.864268551236749, 'Prostate': 6.371386530612245, 'Salivary Gland': 2.327046913580247, 'Skin': 5.700153012714207, 'Small Intestine': 3.029575401069519, 'Spleen': 1.6030402489626556, 'Stomach': 2.4662685236768804, 'Testis': 6.146894736842105, 'Thyroid': 2.4984008575803984, 'Uterus': 11.43550704225352, 'Vagina': 5.8628294871794875}
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|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 42.165372
| 0.857415
| 174
|
O43791
|
P10071
|
nan, 22199232, UNIPROT, nan
|
degron_data, UbiNet, UbiBrowser, 31181401, degron_data
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
GLI3
|
MEAQSHSSTTTEKKKVENSIVKCSTRTDVSEKAVASSTTSNEDESPGQTYHRERRNAITMQPQNVQGLSKVSEEPSTSSDERASLIKKEIHGSLPHVAEPSVPYRGTVFAMDPRNGYMEPHYHPPHLFPAFHPPVPIDARHHEGRYHYDPSPIPPLHMTSALSSSPTYPDLPFIRISPHRNPTAASESPFSPPHPYINPYMDYIRSLHSSPSLSMISATRGLSPTDAPHAGVSPAEYYHQMALLTGQRSPYADIIPSAATAGTGAIHMEYLHAMDSTRFSSPRLSARPSRKRTLSISPLSDHSFDLQTMIRTSPNSLVTILNNSRSSSSASGSYGHLSASAISPALSFTYSSAPVSLHMHQQILSRQQSLGSAFGHSPPLIHPAPTFPTQRPIPGIPTVLNPVQVSSGPSESSQNKPTSESAVSSTGDPMHNKRSKIKPDEDLPSPGARGQQEQPEGTTLVKEEGDKDESKQEPEVIYETNCHWEGCAREFDTQEQLVHHINNDHIHGEKKEFVCRWLDCSREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCTKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDSGSHSQSRSPGRPTQGALGEQQDLSNTTSKREECLQVKTVKAEKPMTSQPSPGGQSSCSSQQSPISNYSNSGLELPLTDGGSIGDLSAIDETPIMDSTISTATTALALQARRNPAGTKWMEHVKLERLKQVNGMFPRLNPILPPKAPAVSPLIGNGTQSNNTCSLGGPMTLLPGRSDLSGVDVTMLNMLNRRDSSASTISSAYLSSRRSSGISPCFSSRRSSEASQAEGRPQNVSVADSYDPISTDASRRSSEASQSDGLPSLLSLTPAQQYRLKAKYAAATGGPPPTPLPNMERMSLKTRLALLGDALEPGVALPPVHAPRRCSDGGAHGYGRRHLQPHDAPGHGVRRASDPVRTGSEGLALPRVPRFSSLSSCNPPAMATSAEKRSLVLQNYTRPEGGQSRNFHSSPCPPSITENVTLESLTMDADANLNDEDFLPDDVVQYLNSQNQAGYEQHFPSALPDDSKVPHGPGDFDAPGLPDSHAGQQFHALEQPCPEGSKTDLPIQWNEVSSGSADLSSSKLKCGPRPAVPQTRAFGFCNGMVVHPQNPLRSGPAGGYQTLGENSNPYGGPEHLMLHNSPGSGTSGNAFHEQPCKAPQYGNCLNRQPVAPGALDGACGAGIQASKLKSTPMQGSGGQLNFGLPVAPNESAGSMVNGMQNQDPVGQGYLAHQLLGDSMQHPGAGRPGQQMLGQISATSHINIYQGPESCLPGAHGMGSQPSSLAVVRGYQPCASFGGSRRQAMPRDSLALQSGQLSDTSQTCRVNGIKMEMKGQPHPLCSNLQNYSGQFYDQTVGFSQQDTKAGSFSISDASCLLQGTSAKNSELLSPGANQVTSTVDSLDSHDLEGVQIDFDAIIDDGDHSSLMSGALSPSIIQNLSHSSSRLTTPRASLPFPALSMSTTNMAIGDMSSLLTSLAEESKFLAVMQ
|
Homo sapiens
|
Nucleus, Cytoplasm, Cell projection, cilium
|
Low tissue specificity
|
{'Ciliated cells': '3.9', 'Basal respiratory cells': '9.1', 'Club cells': '6.4', 'Ionocytes': '3.3', 'Mucus glandular cells': '3.2', 'Serous glandular cells': '6.5', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.1', 'Intestinal goblet cells': '0.2', 'Exocrine glandular cells': '-0.357', 'Basal prostatic cells': '11.9', 'Prostatic glandular cells': '2.6', 'Breast glandular cells': '0.690', 'Breast myoepithelial cells': '0.646', 'Glandular and luminal cells': '6.6', 'Secretory cells': '5.5', 'Basal keratinocytes': '22.0', 'Suprabasal keratinocytes': '14.0', 'Basal squamous epithelial cells': '24.4', 'Squamous epithelial cells': '6.8', 'Alveolar cells type 1': '-0.041', 'Alveolar cells type 2': '-0.128', 'Salivary duct cells': '27.9', 'Ductal cells': '0.443', 'Hepatocytes': '0.038', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.177', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.594', 'Sertoli cells': '-0.293', 'Granulosa cells': '8.1', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.074', 'Excitatory neurons': '0.8', 'Inhibitory neurons': '3.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.4', 'Bipolar cells': '2.1', 'Horizontal cells': '0.0', 'Astrocytes': '285.8', 'Oligodendrocyte precursor cells': '8.0', 'Oligodendrocytes': '0.7', 'Microglial cells': '21.5', 'Muller glia cells': '14.9', 'Schwann cells': '0.118', 'Spermatogonia': '0.174', 'Spermatocytes': '0.090', 'Early spermatids': '0.235', 'Late spermatids': '0.231', 'Oocytes': '0.0', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '43.9', 'Extravillous trophoblasts': '15.3', 'Endothelial cells': '4.2', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.335', 'Skeletal myocytes': '0.000', 'Smooth muscle cells': '17.3', 'Adipocytes': '3.5', 'Melanocytes': '0.237', 'Fibroblasts': '29.6', 'Peritubular cells': '0.069', 'Endometrial stromal cells': '17.3', 'Ovarian stromal cells': '16.6', 'Undifferentiated cells': '0.2', 'T-cells': '0.6', 'B-cells': '0.8', 'Plasma cells': '1.5', 'Nk-cells': '1.5', 'Granulocytes': '4.2', 'Monocytes': '0.4', 'Macrophages': '1.1', 'Hofbauer cells': '1.4', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.296', 'Erythroid cells': '0.070', 'Adipocytes (Subcutaneous)': '-0.116', 'Adipocytes (Visceral)': '-0.196', 'Breast glandular cells (progenitors)': '0.413', 'Adipocytes (Breast)': '-0.510', 'Colon enterocytes': '-0.157', 'Colon enteroendocrine cells': '0.282', 'Enteric glia cells': '-0.060', 'Mitotic cells (Colon)': '-0.132', 'Mitotic cells (Heart)': '0.499', 'Podocytes': '-0.150', 'Ascending Loop of Henle cells': '0.455', 'Intercalated cells': '-0.008', 'Cholangiocyte': '0.480', 'NK-cells (Liver)': '0.096', 'Respiratory ciliated cells': '-0.042', 'Mitotic cells (Lung)': '0.162', 'NK-cells (Lung)': '0.012', 'B-cells (Lung)': '0.023', 'Alpha cells': '0.395', 'Beta cells': '0.166', 'Prostate glandular cells': '-0.482', 'Prostate basal glandular cells': '-0.042', 'Urothelial cells': '0.007', 'Keratinocyte (other)': '0.194', 'Keratinocyte (granular)': '-0.105', 'Hair cortex cells': '0.037', 'Inner root sheath cells': '0.104', 'Outer root sheath cells': '0.330', 'Sebaceous gland cells': '0.056', 'Eccrine sweat gland cells': '0.021', 'Adipocytes (Skin)': '-0.100', 'Mitotic cells (Skin)': '0.358', 'Parietal cells': '-0.761', 'Chief cells': '-0.563', 'Gastric mucous cells': '-0.671', 'Gastric enteroendocrine cells': '-0.426', 'Mitotic cells (Stomach)': '-0.245', 'Parafollicular cells': '0.014', 'Thyroid glandular cells': '0.323', 'Mitotic cells (Thyroid)': '-0.033', 'Adrenal cortex cells': '0.463', 'Adrenal medulla cells': '-0.091', 'Mitotic cells (Adrenal gland)': '0.201', 'Minor salivary glandular cells': '0.324', 'Minor salivary gland ductal cells': '0.307', 'Minor salivary gland basal cells': '0.374', 'Mitotic cells (Minor salivary gland)': '0.397', 'Adipocytes (Minor salivary gland)': '0.315', 'Somatotropes': '-0.429', 'Lactotropes': '-0.403', 'Gonadotropes': '0.013', 'Corticotropes': '-0.261', 'Thyrotropes': '-0.073', 'Undifferentiated cells (Pituitary gland)': '0.639', 'Mitotic cells (Spleen)': '-0.178', 'Platelets': '-0.173', 'Erythrocytes': '0.008', 'Hematopoietic stem cells': '-0.191', 'B-cells (Spleen)': '0.097', 'NK-cells (Spleen)': '0.196', 'Amygdala excitatory': '3.4', 'Cerebellar inhibitory': '0.4', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '1.2', 'Deep-layer intratelencephalic': '0.9', 'Deep-layer near-projecting': '0.5', 'Eccentric medium spiny neuron': '9.6', 'Hippocampal ca1-3': '1.3', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '1.6', 'Lamp5-lhx6 and chandelier': '18.6', 'Lower rhombic lip': '0.4', 'Mammillary body': '0.5', 'Medium spiny neuron': '58.1', 'Mge interneuron': '4.1', 'Midbrain-derived inhibitory': '1.8', 'Miscellaneous': '1.6', 'Splatter': '5.3', 'Thalamic excitatory': '6.7', 'Upper rhombic lip': '0.3', 'Upper-layer intratelencephalic': '1.0', 'Astrocyte': '487.7', 'Bergmann glia': '136.4', 'Central nervous system macrophage': '2.1', 'Choroid plexus epithelial cell': '1.9', 'Committed oligodendrocyte precursor': '6.5', 'Ependymal cell': '145.9', 'Oligodendrocyte': '3.3', 'Oligodendrocyte precursor cell': '4.0', 'Endothelial cell': '18.7', 'Pericyte': '74.3', 'Vascular associated smooth muscle cell': '57.6', 'Fibroblast': '171.7', 'Leukocyte': '8.7', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.1', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '2.2', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.2', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.5', 'Memory CD4 T-cell Th1': '0.1', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '2.6', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.1', 'Terminal effector memory CD8 T-cell': '0.4', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
|
4BLD
|
{'Adipose Tissue': 11.472036544850498, 'Adrenal Gland': 2.778762015503876, 'Bladder': 9.988142857142858, 'Blood': 0.0526365220667384, 'Blood Vessel': 6.339361048689139, 'Brain': 2.060065620741862, 'Breast': 14.980008714596948, 'Cervix Uteri': 16.32184210526316, 'Colon': 15.879546341463415, 'Esophagus': 8.262968166089966, 'Fallopian Tube': 19.44555555555555, 'Heart': 1.1538486643437864, 'Kidney': 1.3765112359550562, 'Liver': 0.2024661061946902, 'Lung': 6.8583823529411765, 'Muscle': 1.003745703611457, 'Nerve': 9.878084006462036, 'Ovary': 19.911316666666664, 'Pancreas': 0.5758686585365853, 'Pituitary': 2.6483752650176675, 'Prostate': 10.056685714285711, 'Salivary Gland': 4.854, 'Skin': 15.34016362631288, 'Small Intestine': 6.553814438502674, 'Spleen': 1.3767572614107884, 'Stomach': 4.31361643454039, 'Testis': 3.281119113573407, 'Thyroid': 11.236532924961717, 'Uterus': 28.286619718309858, 'Vagina': 16.065397435897435}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
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|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 42.286025
| 0.866291
| 176
|
O43791
|
P10275
|
nan, 24508459:25274033, 24508459;25274033, UNIPROT, nan
|
degron_data, UbiNet, UbiBrowser, 31181401, degron_data
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
AR
|
MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
|
Homo sapiens
|
Nucleus, Cytoplasm
|
Tissue enhanced (liver)
|
{'Ciliated cells': '15.0', 'Basal respiratory cells': '0.4', 'Club cells': '36.7', 'Ionocytes': '0.4', 'Mucus glandular cells': '3.3', 'Serous glandular cells': '10.0', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '1.6', 'Paneth cells': '0.1', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.2', 'Exocrine glandular cells': '-0.296', 'Basal prostatic cells': '147.1', 'Prostatic glandular cells': '462.1', 'Breast glandular cells': '0.279', 'Breast myoepithelial cells': '-0.026', 'Glandular and luminal cells': '6.2', 'Secretory cells': '149.4', 'Basal keratinocytes': '8.3', 'Suprabasal keratinocytes': '11.6', 'Basal squamous epithelial cells': '16.2', 'Squamous epithelial cells': '10.4', 'Alveolar cells type 1': '0.152', 'Alveolar cells type 2': '-0.366', 'Salivary duct cells': '4.1', 'Ductal cells': '0.320', 'Hepatocytes': '0.680', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '0.253', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '-0.030', 'Sertoli cells': '0.737', 'Granulosa cells': '33.2', 'Enteroendocrine cells': '0.1', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.578', 'Excitatory neurons': '7.4', 'Inhibitory neurons': '17.2', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '1.9', 'Astrocytes': '26.9', 'Oligodendrocyte precursor cells': '25.0', 'Oligodendrocytes': '0.2', 'Microglial cells': '0.9', 'Muller glia cells': '1.2', 'Schwann cells': '0.114', 'Spermatogonia': '0.485', 'Spermatocytes': '0.151', 'Early spermatids': '-0.518', 'Late spermatids': '-0.680', 'Oocytes': '1.5', 'Cytotrophoblasts': '3.4', 'Syncytiotrophoblasts': '0.8', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '16.7', 'Lymphatic endothelial cells': '14.3', 'Cardiomyocytes': '0.700', 'Skeletal myocytes': '0.521', 'Smooth muscle cells': '33.1', 'Adipocytes': '3.1', 'Melanocytes': '0.028', 'Fibroblasts': '51.9', 'Peritubular cells': '0.583', 'Endometrial stromal cells': '46.2', 'Ovarian stromal cells': '81.2', 'Undifferentiated cells': '0.5', 'T-cells': '2.4', 'B-cells': '0.8', 'Plasma cells': '3.7', 'Nk-cells': '0.1', 'Granulocytes': '3.1', 'Monocytes': '0.0', 'Macrophages': '2.5', 'Hofbauer cells': '0.5', 'Kupffer cells': '6.0', 'Dendritic cells': '30.7', 'Langerhans cells': '0.435', 'Erythroid cells': '-0.066', 'Adipocytes (Subcutaneous)': '0.634', 'Adipocytes (Visceral)': '0.477', 'Breast glandular cells (progenitors)': '0.077', 'Adipocytes (Breast)': '0.221', 'Colon enterocytes': '-0.136', 'Colon enteroendocrine cells': '0.385', 'Enteric glia cells': '0.114', 'Mitotic cells (Colon)': '-0.206', 'Mitotic cells (Heart)': '0.357', 'Podocytes': '-0.061', 'Ascending Loop of Henle cells': '0.491', 'Intercalated cells': '0.043', 'Cholangiocyte': '-0.121', 'NK-cells (Liver)': '0.086', 'Respiratory ciliated cells': '0.098', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.308', 'B-cells (Lung)': '0.136', 'Alpha cells': '0.408', 'Beta cells': '0.284', 'Prostate glandular cells': '0.495', 'Prostate basal glandular cells': '0.189', 'Urothelial cells': '-0.174', 'Keratinocyte (other)': '0.040', 'Keratinocyte (granular)': '0.024', 'Hair cortex cells': '-0.052', 'Inner root sheath cells': '-0.068', 'Outer root sheath cells': '0.051', 'Sebaceous gland cells': '0.476', 'Eccrine sweat gland cells': '0.107', 'Adipocytes (Skin)': '0.198', 'Mitotic cells (Skin)': '0.217', 'Parietal cells': '-0.604', 'Chief cells': '-0.384', 'Gastric mucous cells': '-0.673', 'Gastric enteroendocrine cells': '-0.386', 'Mitotic cells (Stomach)': '-0.238', 'Parafollicular cells': '0.036', 'Thyroid glandular cells': '0.324', 'Mitotic cells (Thyroid)': '0.074', 'Adrenal cortex cells': '0.311', 'Adrenal medulla cells': '-0.029', 'Mitotic cells (Adrenal gland)': '0.184', 'Minor salivary glandular cells': '0.038', 'Minor salivary gland ductal cells': '0.234', 'Minor salivary gland basal cells': '0.144', 'Mitotic cells (Minor salivary gland)': '0.112', 'Adipocytes (Minor salivary gland)': '0.569', 'Somatotropes': '-0.488', 'Lactotropes': '-0.243', 'Gonadotropes': '0.087', 'Corticotropes': '0.040', 'Thyrotropes': '0.135', 'Undifferentiated cells (Pituitary gland)': '0.686', 'Mitotic cells (Spleen)': '-0.164', 'Platelets': '-0.086', 'Erythrocytes': '-0.039', 'Hematopoietic stem cells': '-0.061', 'B-cells (Spleen)': '0.028', 'NK-cells (Spleen)': '0.082', 'Amygdala excitatory': '15.8', 'Cerebellar inhibitory': '4.9', 'Cge interneuron': '7.8', 'Deep-layer corticothalamic and 6b': '3.5', 'Deep-layer intratelencephalic': '1.2', 'Deep-layer near-projecting': '1.5', 'Eccentric medium spiny neuron': '31.7', 'Hippocampal ca1-3': '7.7', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '25.3', 'Lamp5-lhx6 and chandelier': '15.6', 'Lower rhombic lip': '27.4', 'Mammillary body': '20.6', 'Medium spiny neuron': '18.6', 'Mge interneuron': '25.8', 'Midbrain-derived inhibitory': '6.1', 'Miscellaneous': '2.5', 'Splatter': '37.9', 'Thalamic excitatory': '27.9', 'Upper rhombic lip': '2.7', 'Upper-layer intratelencephalic': '7.6', 'Astrocyte': '56.8', 'Bergmann glia': '17.2', 'Central nervous system macrophage': '1.6', 'Choroid plexus epithelial cell': '0.5', 'Committed oligodendrocyte precursor': '28.2', 'Ependymal cell': '14.9', 'Oligodendrocyte': '0.7', 'Oligodendrocyte precursor cell': '39.2', 'Endothelial cell': '4.9', 'Pericyte': '19.2', 'Vascular associated smooth muscle cell': '24.8', 'Fibroblast': '20.7', 'Leukocyte': '1.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.9', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.2', 'Memory CD4 T-cell Th2': '0.3', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.5', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
|
1E3G, 1GS4, 1T5Z, 1T63, 1T65, 1XJ7, 1XOW, 1XQ3, 1Z95, 2AM9, 2AMA, 2AMB, 2AO6, 2AX6, 2AX7, 2AX8, 2AX9, 2AXA, 2HVC, 2OZ7, 2PIO, 2PIP, 2PIQ, 2PIR, 2PIT, 2PIU, 2PIV, 2PIW, 2PIX, 2PKL, 2PNU, 2Q7I, 2Q7J, 2Q7K, 2Q7L, 2YHD, 2YLO, 2YLP, 2YLQ, 2Z4J, 3B5R, 3B65, 3B66, 3B67, 3B68, 3BTR, 3L3X, 3L3Z, 3RLJ, 3RLL, 3V49, 3V4A, 3ZQT, 4HLW, 4K7A, 4OEA, 4OED, 4OEY, 4OEZ, 4OFR, 4OFU, 4OGH, 4OH5, 4OH6, 4OHA, 4OIL, 4OIU, 4OJ9, 4OJB, 4OK1, 4OKB, 4OKT, 4OKW, 4OKX, 4OLM, 4QL8, 5CJ6, 5JJM, 5T8E, 5T8J, 5V8Q, 5VO4, 7ZTX, 7ZTZ, 7ZU1, 7ZU2, 8E1A, 8FGY, 8FGZ, 8FH0, 8FH1, 8FH2, 8RM6, 8RM7
|
{'Adipose Tissue': 8.447334551495016, 'Adrenal Gland': 1.4499135658914728, 'Bladder': 6.807257142857144, 'Blood': 0.0424893240043057, 'Blood Vessel': 10.7155670411985, 'Brain': 0.5966486752460257, 'Breast': 12.724552505446622, 'Cervix Uteri': 40.69978947368421, 'Colon': 2.6580159306803597, 'Esophagus': 2.5342845674740486, 'Fallopian Tube': 22.84777777777778, 'Heart': 3.364557793263647, 'Kidney': 2.174905617977528, 'Liver': 15.16391592920354, 'Lung': 2.92565553633218, 'Muscle': 4.383284308841843, 'Nerve': 5.944082390953151, 'Ovary': 17.63235, 'Pancreas': 0.564131006097561, 'Pituitary': 3.847057950530035, 'Prostate': 22.276032653061225, 'Salivary Gland': 2.126879012345679, 'Skin': 7.679914925373134, 'Small Intestine': 1.650415026737968, 'Spleen': 0.9865611203319502, 'Stomach': 2.154986908077994, 'Testis': 7.635315789473685, 'Thyroid': 4.7274436447166925, 'Uterus': 28.01919014084507, 'Vagina': 26.911480769230767}
|
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0.92, 0.79, 0.92, 0.73, 0.76, 0.92, 0.71, 0.97, 0.92, 0.93, 0.96, 0.99, 0.98, 1.0, 0.96, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.92, 0.97, 0.93, 0.97, 0.92, 0.98, 1.0, 0.95, 0.91, 0.9, 0.89, 0.64, 0.37, 0.59, 0.71, 0.28, 0.47, 0.5, 0.42, 0.52, 0.5, 0.45, 0.21, 0.28, 0.67, 0.75, 0.16, 0.7, 0.46, 0.82, 0.72, 0.94, 0.99, 0.97, 0.99, 0.97, 1.0, 0.99, 1.0, 0.99, 0.99, 1.0, 0.98, 0.93, 0.96, 0.9, 0.96, 0.98, 1.0, 0.85, 0.98, 0.96, 0.97, 0.96, 1.0, 0.97, 1.0, 1.0, 0.99, 0.96, 0.99, 0.93, 1.0, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.93, 0.91, 0.94, 0.95, 1.0, 0.95, 1.0, 0.99, 0.93, 1.0, 0.91, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.95, 1.0, 0.96, 1.0, 0.96, 0.92, 1.0, 0.92, 1.0, 1.0, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.95, 0.96, 0.75, 0.89, 0.86, 0.79, 0.77, 0.84, 0.76, 0.53, 0.84, 0.94, 0.86, 0.77, 0.9, 0.88, 0.95, 0.83, 0.97, 0.96, 0.95, 0.96, 0.96, 0.95, 0.91, 0.98, 0.94, 0.96, 1.0, 0.94, 0.99, 0.99, 0.92, 1.0, 0.93, 0.96, 0.97, 0.96, 0.96, 0.98, 0.94, 0.99, 0.98, 1.0, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.94, 0.98, 1.0, 0.95, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.76, 0.98, 1.0, 1.0, 1.0, 0.99, 1.0, 0.86, 0.79, 0.96, 0.88, 0.91, 1.0, 0.9, 0.94, 0.97, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.93, 0.88, 0.94, 0.88, 0.97, 0.98, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 0.98, 0.93, 0.95, 1.0, 1.0, 1.0, 0.9, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.89, 1.0, 0.95, 0.99, 0.96, 0.98, 0.95, 1.0, 0.9, 0.96, 0.82, 0.99, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 0.92, 0.96, 0.94, 0.96, 1.0, 1.0, 1.0, 0.83, 0.91, 0.86, 0.52, 0.55, 0.58, 0.66, 0.72, 0.82, 0.6, 0.49, 0.72, 0.97, 0.9, 0.33, 0.56, 0.02, 0.52, 0.0, 0.03, 0.56, 0.15, 0.84, 0.16, 0.54, 0.3, 0.65, 0.14, 0.14, 0.4, 0.01, 0.19, 0.0, 0.02, 0.34, 0.38, 0.0, 0.37, 0.51, 0.15, 0.0, 0.44, 0.73, 0.06, 0.28, 0.59, 0.44, 0.95, 0.73, 0.88, 0.36, 0.83, 0.21, 0.98, 0.42, 0.9, 0.46, 0.64, 0.32, 0.55, 0.09, 0.25, 0.55, 0.83, 0.45, 0.15, 0.86, 0.74, 0.03, 0.31, 0.15, 0.02, 0.07, 0.14, 0.43, 0.32, 0.0, 0.5, 0.59, 0.28, 0.45, 0.01, 0.51, 0.29, 0.53, 0.62, 0.72, 0.63, 0.61, 0.99, 0.89, 0.77, 0.97, 0.95, 0.97, 1.0, 1.0, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.91, 0.98, 0.8, 0.9, 0.78, 0.86, 0.92, 0.87, 0.64, 0.94, 0.71, 1.0, 0.96, 0.84, 0.56, 0.64, 0.12, 0.54, 0.22, 0.12, 0.39, 0.35, 0.02, 0.66, 0.26, 0.2, 0.38, 0.41, 0.68, 0.7, 0.16, 0.52, 0.03, 0.79, 0.12, 0.43, 0.47, 0.88, 0.64, 0.85, 0.17, 0.35, 0.17, 0.27, 0.35, 0.0, 0.03, 0.13, 0.11, 0.18, 0.06, 0.33, 0.04, 0.06, 0.09, 0.39, 0.14, 0.0, 0.13, 0.35, 0.12, 0.01, 0.25, 0.04, 0.0, 0.05, 0.29, 0.03, 0.31, 0.32, 0.0, 0.53, 0.67, 0.05, 0.43, 0.31, 0.39, 0.02, 0.07, 0.15, 0.16, 0.0, 0.0, 0.14, 0.11, 0.04, 0.02, 0.1, 0.09, 0.02, 0.12, 0.04, 0.0, 0.14, 0.02, 0.0, 0.15, 0.21, 0.0, 0.26, 0.63, 0.59, 0.17, 0.7, 0.08, 0.76, 0.41, 0.0, 0.16, 0.1, 0.01, 0.44, 0.22, 0.0, 0.21, 0.0, 0.44, 0.43, 0.58, 0.13, 0.0, 0.57, 0.32, 0.0, 0.67, 0.07, 0.38, 0.64, 0.18, 0.01, 0.2, 0.44, 0.03, 0.15, 0.51, 0.03, 0.0, 0.25, 0.33, 0.0, 0.34, 0.67, 0.2, 0.75, 0.05, 0.3, 0.52, 0.37, 0.01, 0.03, 0.14, 0.0, 0.0, 0.06, 0.0, 0.01, 0.02, 0.0, 0.0, 0.06, 0.09, 0.06, 0.17, 0.42, 0.86, 0.35, 0.1, 0.65, 0.41, 0.25, 0.77, 0.21, 0.0, 0.46, 0.38, 0.05, 0.04, 0.34, 0.46, 0.01, 0.11, 0.57, 0.12, 0.0, 0.46, 0.33, 0.04, 0.0, 0.5, 0.54, 0.55, 0.27, 0.66, 0.56, 0.69, 0.68, 0.44, 0.1, 0.52, 0.69, 0.04, 0.23, 0.49, 0.32, 0.0, 0.0, 0.47, 0.04, 0.03, 0.13, 0.35, 0.01, 0.16, 0.46, 0.11, 0.07, 0.54, 0.32, 0.04, 0.03, 0.32, 0.19, 0.12, 0.06, 0.16, 0.08, 0.11, 0.14, 0.45, 0.21, 0.88, 0.87, 0.33, 0.68, 0.05, 0.62, 0.16, 0.09, 0.3, 0.07, 0.04, 0.03, 0.11, 0.02, 0.0, 0.35, 0.57, 0.1, 0.01, 0.16, 0.33, 0.08, 0.13, 0.46, 0.51, 0.63, 0.07, 0.41, 0.36, 0.22, 0.29, 0.16, 0.33, 0.9, 0.78]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 57.193098
| 0.682326
| 612
|
O43791
|
P11308
|
nan, 29202479, 26344095, nan
|
degron_data, UbiBrowser, 31181401, degron_data
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
ERG
|
MASTIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPPNMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAPHPPALPVTSSSFFAAPNPYWNSPTGGIYPNTRLPTSHMPSHLGTYY
|
Homo sapiens
|
Nucleus, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '0.6', 'Basal respiratory cells': '0.6', 'Club cells': '0.4', 'Ionocytes': '0.0', 'Mucus glandular cells': '2.4', 'Serous glandular cells': '0.2', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.557', 'Basal prostatic cells': '1.5', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '-0.287', 'Breast myoepithelial cells': '-0.209', 'Glandular and luminal cells': '1.5', 'Secretory cells': '0.8', 'Basal keratinocytes': '2.2', 'Suprabasal keratinocytes': '1.2', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '0.3', 'Alveolar cells type 1': '0.329', 'Alveolar cells type 2': '-0.318', 'Salivary duct cells': '2.8', 'Ductal cells': '0.620', 'Hepatocytes': '0.451', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '-0.215', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '-0.145', 'Sertoli cells': '0.268', 'Granulosa cells': '0.6', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.418', 'Excitatory neurons': '12.7', 'Inhibitory neurons': '1.7', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.3', 'Oligodendrocyte precursor cells': '6.6', 'Oligodendrocytes': '1.4', 'Microglial cells': '84.1', 'Muller glia cells': '2.6', 'Schwann cells': '0.253', 'Spermatogonia': '0.294', 'Spermatocytes': '-0.071', 'Early spermatids': '-0.392', 'Late spermatids': '-0.519', 'Oocytes': '1.5', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '104.8', 'Lymphatic endothelial cells': '114.2', 'Cardiomyocytes': '0.075', 'Skeletal myocytes': '-0.065', 'Smooth muscle cells': '10.0', 'Adipocytes': '85.9', 'Melanocytes': '-0.180', 'Fibroblasts': '7.8', 'Peritubular cells': '0.532', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '2.5', 'Undifferentiated cells': '0.3', 'T-cells': '0.8', 'B-cells': '0.7', 'Plasma cells': '1.2', 'Nk-cells': '0.0', 'Granulocytes': '24.3', 'Monocytes': '0.7', 'Macrophages': '1.0', 'Hofbauer cells': '0.3', 'Kupffer cells': '6.6', 'Dendritic cells': '0.0', 'Langerhans cells': '-0.091', 'Erythroid cells': '-0.056', 'Adipocytes (Subcutaneous)': '-0.301', 'Adipocytes (Visceral)': '-0.162', 'Breast glandular cells (progenitors)': '-0.397', 'Adipocytes (Breast)': '0.295', 'Colon enterocytes': '0.003', 'Colon enteroendocrine cells': '0.294', 'Enteric glia cells': '0.366', 'Mitotic cells (Colon)': '0.145', 'Mitotic cells (Heart)': '0.355', 'Podocytes': '-0.062', 'Ascending Loop of Henle cells': '0.379', 'Intercalated cells': '-0.212', 'Cholangiocyte': '0.446', 'NK-cells (Liver)': '-0.228', 'Respiratory ciliated cells': '-0.019', 'Mitotic cells (Lung)': '-0.251', 'NK-cells (Lung)': '0.482', 'B-cells (Lung)': '0.120', 'Alpha cells': '0.383', 'Beta cells': '0.199', 'Prostate glandular cells': '-0.323', 'Prostate basal glandular cells': '-0.034', 'Urothelial cells': '0.052', 'Keratinocyte (other)': '-0.546', 'Keratinocyte (granular)': '-0.338', 'Hair cortex cells': '0.261', 'Inner root sheath cells': '0.261', 'Outer root sheath cells': '0.384', 'Sebaceous gland cells': '0.065', 'Eccrine sweat gland cells': '0.479', 'Adipocytes (Skin)': '0.458', 'Mitotic cells (Skin)': '-0.072', 'Parietal cells': '-0.634', 'Chief cells': '-0.548', 'Gastric mucous cells': '-0.481', 'Gastric enteroendocrine cells': '-0.325', 'Mitotic cells (Stomach)': '-0.106', 'Parafollicular cells': '0.004', 'Thyroid glandular cells': '-0.075', 'Mitotic cells (Thyroid)': '0.135', 'Adrenal cortex cells': '-0.029', 'Adrenal medulla cells': '0.111', 'Mitotic cells (Adrenal gland)': '0.147', 'Minor salivary glandular cells': '0.263', 'Minor salivary gland ductal cells': '-0.002', 'Minor salivary gland basal cells': '0.371', 'Mitotic cells (Minor salivary gland)': '0.432', 'Adipocytes (Minor salivary gland)': '0.362', 'Somatotropes': '-0.257', 'Lactotropes': '-0.251', 'Gonadotropes': '0.038', 'Corticotropes': '-0.288', 'Thyrotropes': '-0.111', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.388', 'Platelets': '-0.185', 'Erythrocytes': '-0.169', 'Hematopoietic stem cells': '-0.270', 'B-cells (Spleen)': '0.100', 'NK-cells (Spleen)': '0.241', 'Amygdala excitatory': '1.1', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '0.5', 'Deep-layer corticothalamic and 6b': '33.3', 'Deep-layer intratelencephalic': '0.9', 'Deep-layer near-projecting': '109.7', 'Eccentric medium spiny neuron': '2.6', 'Hippocampal ca1-3': '74.4', 'Hippocampal ca4': '1.5', 'Hippocampal dentate gyrus': '0.4', 'Lamp5-lhx6 and chandelier': '0.5', 'Lower rhombic lip': '0.7', 'Mammillary body': '0.5', 'Medium spiny neuron': '0.8', 'Mge interneuron': '1.6', 'Midbrain-derived inhibitory': '1.3', 'Miscellaneous': '24.5', 'Splatter': '0.7', 'Thalamic excitatory': '6.6', 'Upper rhombic lip': '0.3', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '0.6', 'Bergmann glia': '1.4', 'Central nervous system macrophage': '0.7', 'Choroid plexus epithelial cell': '0.3', 'Committed oligodendrocyte precursor': '1.8', 'Ependymal cell': '1.6', 'Oligodendrocyte': '0.6', 'Oligodendrocyte precursor cell': '0.7', 'Endothelial cell': '838.9', 'Pericyte': '22.4', 'Vascular associated smooth muscle cell': '96.9', 'Fibroblast': '30.5', 'Leukocyte': '1.3', 'Basophil': '1.1', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '2.1', 'NK-cell': '0.0', 'Total PBMC': '0.3', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.3', 'Plasmablast': '0.5', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.6', 'Progenitor cell': '56.2', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
|
1SXE, 4IRG, 4IRH, 4IRI, 5YBC, 5YBD, 6VGE, 6VGG
|
{'Adipose Tissue': 27.097171096345512, 'Adrenal Gland': 3.8122248062015505, 'Bladder': 8.855190476190476, 'Blood': 0.7020397351991389, 'Blood Vessel': 36.23621797752809, 'Brain': 2.205339065102195, 'Breast': 24.698832244008713, 'Cervix Uteri': 15.144473684210526, 'Colon': 6.134833376123235, 'Esophagus': 6.753076539792387, 'Fallopian Tube': 13.941666666666666, 'Heart': 4.7560475029036, 'Kidney': 7.087123595505618, 'Liver': 1.7240482300884956, 'Lung': 28.351273356401386, 'Muscle': 3.2523910336239106, 'Nerve': 12.787132471728594, 'Ovary': 6.480138888888889, 'Pancreas': 1.3034277439024389, 'Pituitary': 3.1934519434628976, 'Prostate': 8.632951020408163, 'Salivary Gland': 4.175735802469136, 'Skin': 4.013784066334992, 'Small Intestine': 7.721390374331551, 'Spleen': 28.1688755186722, 'Stomach': 4.573631197771588, 'Testis': 2.6350554016620498, 'Thyroid': 15.176159264931083, 'Uterus': 19.79999295774648, 'Vagina': 10.543416666666666}
|
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[40.89, 35.87, 42.98, 47.46, 46.45, 44.73, 41.22, 33.22, 34.09, 35.11, 39.61, 35.91, 42.54, 39.46, 43.42, 37.44, 36.76, 41.5, 37.95, 37.82, 34.48, 37.95, 38.6, 37.12, 34.39, 44.44, 39.16, 39.35, 38.97, 38.45, 51.19, 38.88, 57.67, 52.07, 49.88, 40.5, 42.12, 42.12, 44.08, 41.46, 39.88, 43.08, 40.81, 39.4, 42.32, 42.81, 41.65, 34.96, 42.3, 37.97, 38.03, 38.93, 31.98, 35.87, 34.91, 34.2, 39.92, 37.55, 37.03, 40.32, 45.66, 42.22, 36.71, 37.21, 33.68, 41.94, 35.8, 39.94, 33.5, 36.04, 38.01, 37.6, 37.22, 40.35, 40.95, 35.16, 38.27, 39.97, 40.02, 40.22, 41.08, 50.86, 41.52, 40.55, 38.9, 37.78, 41.9, 40.52, 43.45, 39.3, 46.98, 42.78, 45.21, 43.1, 43.82, 41.28, 51.05, 39.7, 43.9, 43.78, 45.51, 47.47, 43.34, 35.31, 46.76, 40.46, 39.93, 55.26, 40.7, 37.81, 43.74, 42.06, 45.88, 44.62, 42.54, 43.35, 34.6, 32.52, 37.95, 40.07, 34.79, 34.41, 36.93, 43.82, 39.82, 56.66, 60.66, 70.31, 67.26, 78.05, 85.44, 87.07, 85.42, 89.95, 89.51, 91.74, 88.27, 89.68, 91.38, 90.08, 85.02, 89.9, 90.9, 87.5, 87.39, 87.4, 88.07, 85.14, 85.03, 84.65, 85.9, 85.59, 83.84, 80.81, 83.93, 86.09, 87.36, 87.76, 89.49, 89.74, 87.51, 89.02, 91.67, 91.26, 90.83, 90.48, 92.27, 92.35, 90.52, 90.95, 89.7, 90.39, 89.17, 91.57, 92.34, 91.48, 91.44, 90.58, 90.29, 89.93, 89.12, 87.23, 87.11, 89.97, 91.02, 86.26, 88.69, 91.18, 89.98, 84.44, 86.32, 89.1, 83.16, 80.51, 82.15, 77.96, 65.88, 54.71, 46.96, 44.04, 37.23, 43.25, 43.26, 49.82, 49.09, 49.46, 54.0, 56.63, 55.7, 55.71, 51.66, 52.96, 53.57, 46.41, 40.33, 41.84, 44.26, 44.99, 37.91, 39.56, 42.28, 40.49, 40.27, 40.26, 29.68, 29.15, 30.73, 31.98, 30.14, 33.04, 29.98, 32.6, 30.24, 34.67, 33.29, 32.45, 32.15, 35.16, 33.29, 38.05, 38.38, 38.43, 32.7, 38.03, 37.41, 40.23, 38.94, 47.77, 42.73, 59.76, 50.04, 44.23, 52.73, 53.9, 52.13, 45.26, 45.35, 47.95, 45.84, 47.27, 51.34, 43.55, 47.39, 43.09, 44.62, 54.44, 47.88, 51.39, 45.3, 46.68, 44.86, 45.79, 45.83, 42.37, 43.62, 45.19, 39.35, 44.47, 38.23, 48.36, 41.55, 35.19, 37.67, 34.52, 35.68, 31.08, 33.66, 37.66, 36.92, 45.43, 48.79, 46.96, 57.83, 54.33, 56.34, 59.84, 59.43, 58.55, 58.06, 56.37, 52.84, 57.22, 58.02, 55.39, 56.14, 55.85, 57.75, 65.48, 71.3, 82.94, 88.59, 91.9, 95.21, 94.21, 91.74, 93.67, 95.46, 91.94, 90.45, 92.98, 93.63, 87.74, 86.93, 90.64, 93.25, 94.02, 95.49, 97.11, 97.5, 97.26, 95.64, 94.62, 89.34, 86.02, 85.55, 83.17, 88.09, 95.31, 96.4, 97.36, 98.07, 97.86, 98.17, 98.27, 98.39, 98.46, 98.42, 98.55, 98.18, 97.15, 96.57, 96.32, 94.88, 92.78, 91.89, 91.45, 92.8, 92.37, 95.98, 97.23, 98.12, 98.41, 97.61, 97.95, 98.2, 98.09, 97.74, 96.64, 97.91, 97.26, 96.85, 96.7, 96.5, 93.64, 91.15, 92.67, 92.72, 94.45, 96.58, 97.07, 97.02, 95.43, 95.58, 94.92, 96.76, 98.11, 97.62, 97.9, 95.54, 94.8, 91.37, 84.76, 83.58, 83.94, 85.07, 80.6, 81.17, 76.51, 76.77, 72.0, 59.13, 48.1, 38.99, 40.94, 33.06, 39.41, 40.23, 34.34, 37.35, 37.16, 37.27, 40.35, 41.79, 40.53, 45.15, 45.48, 41.29, 47.07, 41.28, 37.26, 38.26, 41.34, 39.87, 37.48, 43.89, 47.64, 45.07, 45.5, 44.46, 48.79, 57.24, 48.86, 53.64, 52.69, 55.39, 52.06, 49.79, 53.97, 50.45, 52.3, 42.14, 43.83, 43.68, 40.78, 50.73, 49.28, 37.88, 38.6, 49.58, 37.99, 46.55, 38.06, 52.58, 42.77, 40.59, 52.93, 43.83, 40.5, 45.05, 43.01, 45.47, 53.57, 40.38, 45.82, 44.08, 47.43, 52.25, 46.5, 47.85, 47.34, 53.79, 48.67, 44.59, 49.19, 50.36, 52.12, 47.38, 55.85, 56.9]
|
[1.0, 0.99, 0.99, 0.98, 0.98, 0.99, 1.0, 0.98, 1.0, 0.99, 0.99, 1.0, 0.99, 0.98, 0.99, 0.96, 0.93, 0.93, 0.93, 0.92, 0.75, 0.86, 0.89, 0.98, 1.0, 1.0, 1.0, 0.97, 0.97, 0.97, 0.88, 0.95, 0.93, 0.86, 0.98, 0.92, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.97, 0.94, 0.85, 0.97, 0.68, 0.98, 0.9, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 0.96, 0.95, 0.92, 0.77, 0.96, 0.8, 0.95, 0.97, 0.95, 0.96, 1.0, 1.0, 0.95, 1.0, 0.94, 1.0, 1.0, 0.92, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.98, 0.87, 0.89, 0.92, 0.94, 1.0, 0.94, 0.7, 0.97, 0.76, 0.7, 0.83, 0.78, 0.87, 0.95, 0.9, 0.88, 0.85, 0.77, 0.89, 0.64, 0.89, 0.74, 0.93, 0.76, 0.72, 0.28, 0.85, 0.34, 0.32, 0.55, 0.44, 0.02, 0.37, 0.55, 0.05, 0.42, 0.38, 0.44, 0.25, 0.01, 0.38, 0.25, 0.02, 0.01, 0.26, 0.32, 0.0, 0.24, 0.82, 0.68, 0.32, 0.65, 0.06, 0.61, 0.81, 0.13, 0.45, 0.3, 0.66, 0.48, 0.02, 0.59, 0.9, 0.16, 0.31, 0.0, 0.55, 0.49, 0.0, 0.15, 0.66, 0.16, 0.5, 0.4, 0.62, 0.34, 0.0, 0.42, 0.77, 0.23, 0.07, 0.57, 0.49, 0.66, 0.01, 0.01, 0.37, 0.22, 0.01, 0.26, 0.44, 0.1, 0.02, 0.56, 0.36, 0.17, 0.55, 0.69, 0.18, 0.81, 0.56, 0.65, 0.28, 0.3, 0.49, 0.43, 0.52, 0.38, 0.23, 0.46, 0.59, 0.32, 0.32, 0.64, 0.69, 0.29, 0.67, 0.83, 0.47, 0.58, 0.66, 0.55, 0.92, 0.92, 0.66, 1.0, 0.89, 0.82, 0.87, 0.65, 0.89, 0.75, 0.84, 0.92, 0.83, 0.93, 0.89, 0.98, 0.98, 0.96, 1.0, 0.98, 1.0, 1.0, 1.0, 0.96, 1.0, 0.94, 1.0, 0.91, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.99, 0.92, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.92, 0.99, 0.88, 0.96, 0.91, 0.86, 0.92, 0.86, 0.78, 0.86, 0.81, 0.83, 0.82, 0.79, 0.71, 0.34, 0.3, 0.04, 0.63, 0.53, 0.21, 0.02, 0.36, 0.19, 0.02, 0.33, 0.54, 0.45, 0.06, 0.73, 0.81, 0.68, 0.25, 0.52, 0.88, 0.04, 0.48, 0.03, 0.03, 0.07, 0.01, 0.0, 0.02, 0.23, 0.07, 0.07, 0.43, 0.49, 0.73, 0.69, 0.11, 0.34, 0.68, 0.02, 0.01, 0.23, 0.25, 0.34, 0.85, 0.56, 0.5, 0.01, 0.11, 0.0, 0.3, 0.03, 0.42, 0.42, 0.1, 0.6, 0.24, 0.0, 0.0, 0.54, 0.3, 0.1, 0.06, 0.63, 0.26, 0.26, 0.78, 0.55, 0.87, 0.77, 0.22, 0.46, 0.2, 0.63, 0.51, 0.0, 0.05, 0.47, 0.31, 0.0, 0.4, 0.56, 0.12, 0.34, 0.87, 0.64, 0.5, 0.07, 0.0, 0.49, 0.5, 0.16, 0.8, 0.99, 0.34, 0.94, 0.35, 0.04, 0.04, 0.31, 0.04, 0.28, 0.3, 0.7, 0.02, 0.03, 0.45, 0.63, 0.3, 0.36, 0.55, 0.8, 0.85, 0.78, 0.94, 0.92, 0.82, 0.91, 0.82, 0.91, 0.8, 0.89, 0.92, 0.8, 0.97, 0.99, 0.93, 0.93, 0.91, 0.6, 0.94, 0.95, 1.0, 0.99, 0.81, 0.99, 0.82, 1.0, 0.95, 1.0, 0.97, 1.0, 0.94, 1.0, 0.98, 1.0, 1.0, 0.99, 0.98, 1.0, 0.98, 1.0, 1.0, 0.93, 1.0, 0.94, 1.0, 0.99, 1.0, 0.98, 0.99, 1.0, 0.99, 1.0, 0.97, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.99, 1.0, 1.0, 0.9, 1.0, 0.92, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.98, 0.99, 0.98]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 59.302693
| 0.691232
| 1,660
|
O43791
|
P24864
|
30237511
|
UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
CCNE1
|
MPRERRERDAKERDTMKEDGGAEFSARSRKRKANVTVFLQDPDEEMAKIDRTARDQCGSQPWDNNAVCADPCSLIPTPDKEDDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKKQSSGPEMA
|
Homo sapiens
|
Nucleus
|
Tissue enhanced (bone marrow, placenta)
|
{'Ciliated cells': '2.1', 'Basal respiratory cells': '0.1', 'Club cells': '0.8', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '5.0', 'Gastric mucus-secreting cells': '2.9', 'Proximal enterocytes': '0.8', 'Paneth cells': '1.2', 'Distal enterocytes': '2.7', 'Intestinal goblet cells': '5.9', 'Exocrine glandular cells': '-0.191', 'Basal prostatic cells': '0.6', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.079', 'Breast myoepithelial cells': '-0.118', 'Glandular and luminal cells': '18.5', 'Secretory cells': '1.3', 'Basal keratinocytes': '3.9', 'Suprabasal keratinocytes': '6.6', 'Basal squamous epithelial cells': '4.4', 'Squamous epithelial cells': '8.6', 'Alveolar cells type 1': '-0.226', 'Alveolar cells type 2': '-0.038', 'Salivary duct cells': '1.1', 'Ductal cells': '0.186', 'Hepatocytes': '0.196', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.000', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.160', 'Sertoli cells': '-0.159', 'Granulosa cells': '4.5', 'Enteroendocrine cells': '3.7', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '-0.261', 'Excitatory neurons': '2.8', 'Inhibitory neurons': '4.9', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '1.6', 'Bipolar cells': '2.2', 'Horizontal cells': '6.3', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '2.4', 'Oligodendrocytes': '1.3', 'Microglial cells': '0.0', 'Muller glia cells': '2.0', 'Schwann cells': '-0.041', 'Spermatogonia': '0.005', 'Spermatocytes': '0.442', 'Early spermatids': '0.503', 'Late spermatids': '0.156', 'Oocytes': '10.3', 'Cytotrophoblasts': '146.9', 'Syncytiotrophoblasts': '85.1', 'Extravillous trophoblasts': '2071.7', 'Endothelial cells': '0.9', 'Lymphatic endothelial cells': '0.2', 'Cardiomyocytes': '0.549', 'Skeletal myocytes': '-0.336', 'Smooth muscle cells': '3.0', 'Adipocytes': '2.7', 'Melanocytes': '0.133', 'Fibroblasts': '2.6', 'Peritubular cells': '-0.143', 'Endometrial stromal cells': '3.7', 'Ovarian stromal cells': '0.6', 'Undifferentiated cells': '10.7', 'T-cells': '3.4', 'B-cells': '2.6', 'Plasma cells': '16.0', 'Nk-cells': '0.7', 'Granulocytes': '0.7', 'Monocytes': '6.1', 'Macrophages': '4.1', 'Hofbauer cells': '17.8', 'Kupffer cells': '0.3', 'Dendritic cells': '0.8', 'Langerhans cells': '0.179', 'Erythroid cells': '-0.009', 'Adipocytes (Subcutaneous)': '0.210', 'Adipocytes (Visceral)': '0.208', 'Breast glandular cells (progenitors)': '0.014', 'Adipocytes (Breast)': '0.050', 'Colon enterocytes': '0.075', 'Colon enteroendocrine cells': '-0.075', 'Enteric glia cells': '-0.225', 'Mitotic cells (Colon)': '0.087', 'Mitotic cells (Heart)': '0.459', 'Podocytes': '-0.265', 'Ascending Loop of Henle cells': '0.401', 'Intercalated cells': '-0.152', 'Cholangiocyte': '0.368', 'NK-cells (Liver)': '-0.153', 'Respiratory ciliated cells': '0.008', 'Mitotic cells (Lung)': '0.543', 'NK-cells (Lung)': '0.031', 'B-cells (Lung)': '0.136', 'Alpha cells': '0.153', 'Beta cells': '0.121', 'Prostate glandular cells': '-0.198', 'Prostate basal glandular cells': '0.064', 'Urothelial cells': '0.035', 'Keratinocyte (other)': '0.238', 'Keratinocyte (granular)': '0.508', 'Hair cortex cells': '-0.217', 'Inner root sheath cells': '-0.195', 'Outer root sheath cells': '-0.287', 'Sebaceous gland cells': '-0.025', 'Eccrine sweat gland cells': '-0.357', 'Adipocytes (Skin)': '-0.214', 'Mitotic cells (Skin)': '-0.007', 'Parietal cells': '-0.243', 'Chief cells': '-0.309', 'Gastric mucous cells': '0.172', 'Gastric enteroendocrine cells': '-0.187', 'Mitotic cells (Stomach)': '0.476', 'Parafollicular cells': '0.031', 'Thyroid glandular cells': '0.242', 'Mitotic cells (Thyroid)': '0.008', 'Adrenal cortex cells': '0.210', 'Adrenal medulla cells': '-0.121', 'Mitotic cells (Adrenal gland)': '0.299', 'Minor salivary glandular cells': '0.217', 'Minor salivary gland ductal cells': '-0.211', 'Minor salivary gland basal cells': '0.648', 'Mitotic cells (Minor salivary gland)': '0.738', 'Adipocytes (Minor salivary gland)': '0.191', 'Somatotropes': '-0.203', 'Lactotropes': '-0.290', 'Gonadotropes': '-0.184', 'Corticotropes': '-0.056', 'Thyrotropes': '0.008', 'Undifferentiated cells (Pituitary gland)': '0.247', 'Mitotic cells (Spleen)': '0.761', 'Platelets': '0.137', 'Erythrocytes': '0.250', 'Hematopoietic stem cells': '0.248', 'B-cells (Spleen)': '-0.045', 'NK-cells (Spleen)': '-0.184', 'Amygdala excitatory': '3.2', 'Cerebellar inhibitory': '6.3', 'Cge interneuron': '8.4', 'Deep-layer corticothalamic and 6b': '3.9', 'Deep-layer intratelencephalic': '2.6', 'Deep-layer near-projecting': '4.0', 'Eccentric medium spiny neuron': '4.0', 'Hippocampal ca1-3': '4.4', 'Hippocampal ca4': '3.1', 'Hippocampal dentate gyrus': '4.7', 'Lamp5-lhx6 and chandelier': '5.7', 'Lower rhombic lip': '4.8', 'Mammillary body': '5.1', 'Medium spiny neuron': '4.8', 'Mge interneuron': '9.2', 'Midbrain-derived inhibitory': '7.4', 'Miscellaneous': '3.6', 'Splatter': '5.2', 'Thalamic excitatory': '6.0', 'Upper rhombic lip': '4.9', 'Upper-layer intratelencephalic': '2.8', 'Astrocyte': '2.7', 'Bergmann glia': '0.4', 'Central nervous system macrophage': '1.4', 'Choroid plexus epithelial cell': '0.5', 'Committed oligodendrocyte precursor': '3.0', 'Ependymal cell': '0.8', 'Oligodendrocyte': '1.7', 'Oligodendrocyte precursor cell': '2.7', 'Endothelial cell': '0.6', 'Pericyte': '1.1', 'Vascular associated smooth muscle cell': '0.5', 'Fibroblast': '1.1', 'Leukocyte': '1.8', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.4', 'Classical monocyte': '1.4', 'Non-classical monocyte': '22.1', 'Intermediate monocyte': '1.6', 'T-reg': '2.4', 'GdT-cell': '0.1', 'MAIT T-cell': '0.2', 'Memory CD4 T-cell': '0.1', 'Naive CD4 T-cell': '10.9', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '10.9', 'Memory B-cell': '0.6', 'Naive B-cell': '2.6', 'Plasmacytoid DC': '0.8', 'Myeloid DC': '0.4', 'NK-cell': '2.3', 'Total PBMC': '0.4', 'Vd2 gdTCR': '0.7', 'Memory CD4 T-cell Th1\\/Th17': '3.5', 'Memory CD4 T-cell Th17': '10.0', 'Memory CD4 T-cell Th2': '12.6', 'Non-Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1': '6.7', 'Memory CD4 T-cell TFH': '11.4', 'Terminal effector memory CD4 T-cell': '1.5', 'Central memory CD8 T-cell': '1.4', 'Effector memory CD8 T-cell': '0.1', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '2.7', 'Plasmablast': '12.6', 'Switched memory B-cell': '2.9', 'Exhausted memory B-cell': '3.0', 'Progenitor cell': '0.9', 'Memory T-reg': '20.3', 'Naive CD4 T-cell activated': '4.2', 'Naive CD8 T-cell activated': '6.7', 'Naive T-reg': '13.8'}
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1W98, 5L2W, 7KJS, 7XQK, 8H4R, 8H6P, 8H6T, 8VQ3, 8VQ4
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{'Adipose Tissue': 1.399527242524917, 'Adrenal Gland': 8.372401937984497, 'Bladder': 3.9990238095238095, 'Blood': 6.10497487621098, 'Blood Vessel': 1.0825937078651686, 'Brain': 4.232462679788039, 'Breast': 1.310756448801743, 'Cervix Uteri': 1.7519052631578949, 'Colon': 4.156634017971759, 'Esophagus': 4.5748903114186845, 'Fallopian Tube': 1.487766666666667, 'Heart': 1.7322625783972128, 'Kidney': 1.1923685393258427, 'Liver': 0.5951428761061947, 'Lung': 2.3483027681660897, 'Muscle': 1.6197785678704857, 'Nerve': 4.278850888529887, 'Ovary': 1.5761694444444443, 'Pancreas': 0.8909765243902439, 'Pituitary': 2.0698681978798588, 'Prostate': 2.322377142857143, 'Salivary Gland': 2.538495061728395, 'Skin': 6.624410503040354, 'Small Intestine': 4.073737967914439, 'Spleen': 7.507618257261411, 'Stomach': 2.616608635097493, 'Testis': 28.481880886426595, 'Thyroid': 3.492701071975498, 'Uterus': 1.3871647887323943, 'Vagina': 3.5122333333333335}
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[40.56, 43.22, 41.81, 43.27, 36.16, 46.85, 35.08, 46.59, 35.7, 38.8, 37.6, 37.3, 37.59, 37.33, 38.9, 36.51, 38.61, 35.51, 34.24, 32.86, 31.59, 34.12, 27.59, 31.5, 30.53, 30.89, 29.0, 31.47, 28.63, 32.92, 34.0, 32.28, 37.27, 35.87, 42.61, 37.0, 39.46, 45.58, 44.46, 45.32, 47.72, 45.65, 49.73, 59.21, 55.32, 53.28, 57.3, 59.35, 55.83, 49.33, 56.22, 53.75, 44.19, 46.83, 51.68, 50.61, 37.79, 34.31, 31.43, 29.1, 30.35, 27.79, 31.03, 31.12, 30.46, 34.02, 28.54, 33.49, 31.34, 33.46, 36.98, 37.03, 33.43, 38.23, 36.81, 36.55, 41.83, 37.78, 43.74, 41.39, 37.52, 39.86, 37.84, 35.02, 36.54, 31.29, 39.23, 37.76, 38.09, 34.18, 33.45, 29.88, 35.7, 36.99, 35.14, 44.87, 38.41, 46.0, 46.7, 55.29, 69.05, 78.56, 88.59, 92.87, 93.11, 91.86, 91.6, 92.19, 91.59, 93.22, 95.15, 95.13, 94.06, 94.59, 95.95, 96.1, 95.24, 95.01, 96.18, 96.52, 94.78, 95.38, 95.63, 92.7, 92.75, 96.1, 97.28, 95.66, 97.43, 95.76, 96.68, 97.21, 97.18, 96.67, 96.6, 96.79, 97.93, 96.77, 96.81, 97.87, 97.14, 97.41, 97.12, 98.29, 98.54, 98.51, 98.5, 98.69, 98.82, 98.75, 98.69, 98.84, 98.77, 98.57, 98.55, 98.76, 98.33, 97.84, 98.19, 98.38, 98.7, 98.76, 98.8, 98.81, 98.89, 98.92, 98.91, 98.92, 98.93, 98.87, 98.89, 98.87, 98.88, 98.75, 98.67, 98.73, 98.62, 98.24, 98.07, 98.24, 97.67, 97.15, 97.98, 97.3, 97.42, 96.84, 98.08, 98.52, 98.5, 98.82, 98.85, 98.85, 98.83, 98.9, 98.92, 98.93, 98.9, 98.92, 98.92, 98.86, 98.75, 98.68, 98.53, 98.39, 98.26, 97.64, 98.05, 98.29, 98.38, 98.58, 98.27, 98.45, 98.62, 98.2, 98.03, 97.49, 97.01, 96.91, 95.39, 97.06, 97.7, 98.32, 98.48, 98.65, 98.67, 98.83, 98.81, 98.78, 98.77, 98.69, 98.75, 98.76, 98.86, 98.81, 98.68, 98.55, 98.64, 98.41, 98.42, 98.39, 98.5, 98.31, 98.35, 98.39, 98.67, 98.74, 98.57, 98.15, 98.37, 98.23, 97.41, 96.46, 97.16, 96.79, 95.01, 94.46, 94.58, 93.32, 88.79, 86.83, 83.62, 81.52, 78.04, 83.81, 85.45, 85.42, 83.75, 87.47, 87.04, 94.15, 95.58, 96.54, 96.09, 95.87, 97.78, 97.04, 96.18, 97.95, 98.29, 97.52, 98.09, 98.66, 98.55, 98.22, 98.48, 98.49, 98.5, 97.97, 97.77, 97.45, 98.01, 98.14, 97.39, 97.8, 97.54, 98.49, 97.8, 98.02, 98.62, 98.62, 98.33, 98.52, 98.52, 97.9, 97.89, 96.9, 95.59, 94.59, 94.7, 94.15, 94.67, 95.42, 95.79, 94.84, 94.4, 95.29, 95.37, 94.05, 94.65, 94.71, 93.82, 94.55, 94.58, 96.22, 96.72, 97.2, 98.16, 97.58, 96.37, 97.16, 98.09, 97.1, 97.34, 97.83, 96.82, 95.82, 96.43, 95.38, 93.13, 94.44, 92.79, 90.09, 88.21, 90.8, 94.59, 95.23, 96.42, 96.35, 96.81, 96.6, 95.81, 96.39, 96.52, 94.84, 94.59, 95.98, 97.24, 97.26, 97.97, 98.45, 98.68, 98.13, 97.72, 94.01, 93.2, 93.33, 97.0, 96.75, 96.53, 96.96, 96.65, 95.97, 95.62, 93.96, 94.62, 93.16, 91.62, 90.86, 90.36, 87.19, 84.11, 82.54, 78.04, 73.42, 73.18, 65.99, 52.74, 49.82, 46.85, 47.04, 43.49, 45.28, 43.83, 51.9, 57.63, 53.9, 58.39, 54.48, 55.54, 53.14, 49.26, 43.04, 51.71, 50.59, 49.82, 48.75, 49.96, 53.36, 52.53, 58.05]
|
[1.0, 0.99, 1.0, 0.92, 0.83, 0.89, 0.74, 0.92, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.89, 0.94, 0.89, 0.76, 0.75, 0.86, 0.8, 0.89, 0.91, 0.87, 0.92, 0.54, 0.87, 0.28, 0.66, 0.36, 0.67, 0.54, 0.21, 0.58, 0.24, 0.66, 0.51, 0.05, 0.39, 0.38, 0.32, 0.05, 0.64, 0.67, 0.31, 0.29, 0.79, 0.79, 0.62, 0.78, 0.73, 0.88, 0.93, 0.93, 0.95, 0.95, 0.95, 0.97, 0.96, 0.94, 0.94, 0.95, 1.0, 0.96, 0.99, 0.94, 1.0, 0.93, 0.94, 0.93, 0.95, 0.99, 0.99, 1.0, 0.98, 1.0, 1.0, 0.87, 0.97, 0.82, 0.92, 0.84, 0.91, 0.7, 0.83, 0.77, 0.76, 0.85, 0.6, 0.77, 0.62, 0.58, 0.99, 0.19, 0.69, 0.23, 0.13, 0.06, 0.12, 0.8, 0.11, 0.99, 0.55, 0.48, 0.53, 0.35, 0.61, 0.56, 0.23, 0.02, 0.64, 0.59, 0.14, 0.19, 0.42, 0.32, 0.16, 0.59, 0.61, 0.08, 0.77, 0.28, 0.39, 0.27, 0.57, 0.0, 0.15, 0.71, 0.37, 0.0, 0.69, 0.67, 0.12, 0.64, 0.38, 0.41, 0.2, 0.02, 0.0, 0.48, 0.08, 0.0, 0.08, 0.23, 0.0, 0.01, 0.45, 0.02, 0.0, 0.22, 0.63, 0.26, 0.35, 0.03, 0.29, 0.01, 0.22, 0.0, 0.0, 0.01, 0.04, 0.01, 0.0, 0.0, 0.0, 0.01, 0.05, 0.12, 0.03, 0.0, 0.31, 0.55, 0.28, 0.87, 0.63, 0.07, 0.41, 0.63, 0.82, 0.39, 0.07, 0.28, 0.09, 0.03, 0.0, 0.0, 0.0, 0.0, 0.0, 0.07, 0.02, 0.0, 0.0, 0.44, 0.52, 0.5, 0.15, 0.94, 0.94, 0.23, 0.11, 0.56, 0.24, 0.73, 0.34, 0.0, 0.17, 0.78, 0.25, 0.03, 0.89, 0.78, 0.58, 0.04, 0.41, 0.21, 0.67, 0.43, 0.0, 0.38, 0.55, 0.08, 0.09, 0.46, 0.46, 0.0, 0.08, 0.63, 0.28, 0.07, 0.79, 0.58, 0.49, 0.1, 0.62, 0.09, 0.19, 0.0, 0.02, 0.03, 0.18, 0.01, 0.0, 0.28, 0.26, 0.0, 0.01, 0.05, 0.04, 0.11, 0.16, 0.24, 0.36, 0.79, 0.71, 0.46, 0.41, 0.22, 0.72, 0.58, 0.69, 0.36, 0.13, 0.37, 0.2, 0.36, 0.17, 0.01, 0.06, 0.22, 0.01, 0.02, 0.05, 0.0, 0.03, 0.04, 0.02, 0.01, 0.02, 0.0, 0.06, 0.08, 0.35, 0.01, 0.06, 0.6, 0.12, 0.22, 0.01, 0.0, 0.12, 0.02, 0.0, 0.0, 0.0, 0.0, 0.04, 0.07, 0.02, 0.05, 0.19, 0.34, 0.25, 0.72, 0.16, 0.0, 0.55, 0.57, 0.0, 0.01, 0.23, 0.07, 0.5, 0.06, 0.67, 0.3, 0.0, 0.19, 0.7, 0.01, 0.0, 0.45, 0.13, 0.0, 0.09, 0.04, 0.0, 0.05, 0.19, 0.03, 0.02, 0.24, 0.62, 0.48, 0.43, 0.38, 0.3, 0.85, 0.41, 0.35, 0.72, 0.08, 0.87, 1.0, 0.22, 0.49, 0.56, 0.75, 0.31, 0.03, 0.03, 0.24, 0.01, 0.0, 0.19, 0.3, 0.28, 0.53, 0.07, 0.27, 0.5, 0.01, 0.01, 0.42, 0.44, 0.0, 0.26, 0.43, 0.22, 0.29, 0.48, 0.58, 0.18, 0.42, 0.66, 0.59, 0.73, 0.82, 0.72, 0.68, 0.89, 0.89, 0.86, 0.84, 0.61, 0.81, 0.87, 0.77, 0.87, 0.95, 0.92, 0.94, 0.83, 0.99, 0.98, 0.99, 0.95, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 79.345439
| 0.44061
| 1,939
|
O43791
|
P25440
|
28805820:28805822, 28805821
|
UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
BRD2
|
MLQNVTPHNKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAKLAALQGSVTSAHQVPAVSSVSHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRLSASSSSSDSSSSSSSSSSSDTSDSDSG
|
Homo sapiens
|
Nucleus, Chromosome
|
Low tissue specificity
|
{'Ciliated cells': '129.7', 'Basal respiratory cells': '71.7', 'Club cells': '105.5', 'Ionocytes': '85.0', 'Mucus glandular cells': '144.1', 'Serous glandular cells': '97.1', 'Gastric mucus-secreting cells': '209.3', 'Proximal enterocytes': '128.0', 'Paneth cells': '138.6', 'Distal enterocytes': '168.3', 'Intestinal goblet cells': '194.3', 'Exocrine glandular cells': '-0.775', 'Basal prostatic cells': '213.4', 'Prostatic glandular cells': '97.1', 'Breast glandular cells': '0.646', 'Breast myoepithelial cells': '0.609', 'Glandular and luminal cells': '245.5', 'Secretory cells': '118.4', 'Basal keratinocytes': '170.0', 'Suprabasal keratinocytes': '172.7', 'Basal squamous epithelial cells': '392.7', 'Squamous epithelial cells': '329.6', 'Alveolar cells type 1': '0.321', 'Alveolar cells type 2': '-0.382', 'Salivary duct cells': '201.3', 'Ductal cells': '0.613', 'Hepatocytes': '0.251', 'Cholangiocytes': '99.2', 'Proximal tubular cells': '0.136', 'Distal tubular cells': '15.4', 'Collecting duct cells': '50.6', 'Mesothelial cells': '0.387', 'Sertoli cells': '0.097', 'Granulosa cells': '137.5', 'Enteroendocrine cells': '198.6', 'Pancreatic endocrine cells': '34.0', 'Leydig cells': '0.027', 'Excitatory neurons': '15.6', 'Inhibitory neurons': '19.0', 'Cone photoreceptor cells': '61.2', 'Rod photoreceptor cells': '67.1', 'Bipolar cells': '64.5', 'Horizontal cells': '79.9', 'Astrocytes': '36.2', 'Oligodendrocyte precursor cells': '14.1', 'Oligodendrocytes': '20.6', 'Microglial cells': '25.0', 'Muller glia cells': '59.0', 'Schwann cells': '0.115', 'Spermatogonia': '0.430', 'Spermatocytes': '0.451', 'Early spermatids': '0.240', 'Late spermatids': '0.141', 'Oocytes': '72.8', 'Cytotrophoblasts': '92.8', 'Syncytiotrophoblasts': '214.2', 'Extravillous trophoblasts': '152.7', 'Endothelial cells': '162.1', 'Lymphatic endothelial cells': '91.0', 'Cardiomyocytes': '0.505', 'Skeletal myocytes': '-0.215', 'Smooth muscle cells': '200.9', 'Adipocytes': '298.8', 'Melanocytes': '0.187', 'Fibroblasts': '181.9', 'Peritubular cells': '0.068', 'Endometrial stromal cells': '137.6', 'Ovarian stromal cells': '102.6', 'Undifferentiated cells': '132.2', 'T-cells': '340.1', 'B-cells': '287.2', 'Plasma cells': '267.1', 'Nk-cells': '254.3', 'Granulocytes': '129.4', 'Monocytes': '269.1', 'Macrophages': '195.7', 'Hofbauer cells': '87.5', 'Kupffer cells': '88.6', 'Dendritic cells': '258.5', 'Langerhans cells': '0.295', 'Erythroid cells': '-0.088', 'Adipocytes (Subcutaneous)': '-0.257', 'Adipocytes (Visceral)': '-0.197', 'Breast glandular cells (progenitors)': '0.519', 'Adipocytes (Breast)': '-0.594', 'Colon enterocytes': '-0.221', 'Colon enteroendocrine cells': '0.329', 'Enteric glia cells': '0.160', 'Mitotic cells (Colon)': '-0.138', 'Mitotic cells (Heart)': '0.464', 'Podocytes': '-0.141', 'Ascending Loop of Henle cells': '0.486', 'Intercalated cells': '-0.042', 'Cholangiocyte': '0.262', 'NK-cells (Liver)': '-0.155', 'Respiratory ciliated cells': '0.116', 'Mitotic cells (Lung)': '-0.325', 'NK-cells (Lung)': '0.411', 'B-cells (Lung)': '0.091', 'Alpha cells': '0.359', 'Beta cells': '0.208', 'Prostate glandular cells': '0.038', 'Prostate basal glandular cells': '0.390', 'Urothelial cells': '0.350', 'Keratinocyte (other)': '0.430', 'Keratinocyte (granular)': '-0.076', 'Hair cortex cells': '-0.105', 'Inner root sheath cells': '-0.009', 'Outer root sheath cells': '0.173', 'Sebaceous gland cells': '-0.072', 'Eccrine sweat gland cells': '-0.074', 'Adipocytes (Skin)': '-0.373', 'Mitotic cells (Skin)': '0.316', 'Parietal cells': '-0.593', 'Chief cells': '-0.469', 'Gastric mucous cells': '-0.283', 'Gastric enteroendocrine cells': '-0.355', 'Mitotic cells (Stomach)': '0.075', 'Parafollicular cells': '0.151', 'Thyroid glandular cells': '0.532', 'Mitotic cells (Thyroid)': '-0.103', 'Adrenal cortex cells': '0.271', 'Adrenal medulla cells': '0.043', 'Mitotic cells (Adrenal gland)': '0.126', 'Minor salivary glandular cells': '0.542', 'Minor salivary gland ductal cells': '0.247', 'Minor salivary gland basal cells': '0.208', 'Mitotic cells (Minor salivary gland)': '0.196', 'Adipocytes (Minor salivary gland)': '0.123', 'Somatotropes': '0.005', 'Lactotropes': '0.073', 'Gonadotropes': '0.144', 'Corticotropes': '-0.066', 'Thyrotropes': '0.163', 'Undifferentiated cells (Pituitary gland)': '0.300', 'Mitotic cells (Spleen)': '-0.224', 'Platelets': '-0.191', 'Erythrocytes': '-0.107', 'Hematopoietic stem cells': '-0.312', 'B-cells (Spleen)': '0.405', 'NK-cells (Spleen)': '0.335', 'Amygdala excitatory': '21.9', 'Cerebellar inhibitory': '30.3', 'Cge interneuron': '33.6', 'Deep-layer corticothalamic and 6b': '22.5', 'Deep-layer intratelencephalic': '23.0', 'Deep-layer near-projecting': '24.2', 'Eccentric medium spiny neuron': '28.5', 'Hippocampal ca1-3': '30.6', 'Hippocampal ca4': '26.4', 'Hippocampal dentate gyrus': '19.5', 'Lamp5-lhx6 and chandelier': '34.3', 'Lower rhombic lip': '21.9', 'Mammillary body': '27.1', 'Medium spiny neuron': '24.9', 'Mge interneuron': 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'Plasmacytoid DC': '193.2', 'Myeloid DC': '152.4', 'NK-cell': '394.3', 'Total PBMC': '119.2', 'Vd2 gdTCR': '195.2', 'Memory CD4 T-cell Th1\\/Th17': '258.8', 'Memory CD4 T-cell Th17': '263.1', 'Memory CD4 T-cell Th2': '290.8', 'Non-Vd2 gdTCR': '229.4', 'Memory CD4 T-cell Th1': '272.8', 'Memory CD4 T-cell TFH': '221.2', 'Terminal effector memory CD4 T-cell': '147.6', 'Central memory CD8 T-cell': '180.4', 'Effector memory CD8 T-cell': '203.4', 'Terminal effector memory CD8 T-cell': '210.4', 'Non-switched memory B-cell': '143.2', 'Plasmablast': '189.9', 'Switched memory B-cell': '155.7', 'Exhausted memory B-cell': '147.6', 'Progenitor cell': '110.5', 'Memory T-reg': '270.8', 'Naive CD4 T-cell activated': '339.1', 'Naive CD8 T-cell activated': '385.3', 'Naive T-reg': '198.1'}
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{'Adipose Tissue': 116.28168604651162, 'Adrenal Gland': 91.65496124031009, 'Bladder': 130.15142857142857, 'Blood': 86.66935952637245, 'Blood Vessel': 140.09986516853934, 'Brain': 70.78361582134747, 'Breast': 122.3345751633987, 'Cervix Uteri': 163.11157894736843, 'Colon': 109.6439024390244, 'Esophagus': 107.81532179930797, 'Fallopian Tube': 167.35555555555555, 'Heart': 39.19981300813008, 'Kidney': 77.90516853932584, 'Liver': 52.40646017699115, 'Lung': 143.6972491349481, 'Muscle': 56.585716064757165, 'Nerve': 161.09531502423263, 'Ovary': 174.5061111111111, 'Pancreas': 56.459207317073165, 'Pituitary': 154.32010600706712, 'Prostate': 140.08416326530613, 'Salivary Gland': 103.08827160493829, 'Skin': 117.4582918739635, 'Small Intestine': 117.76181818181816, 'Spleen': 153.50684647302904, 'Stomach': 95.35612813370471, 'Testis': 175.8845706371191, 'Thyroid': 202.58079632465544, 'Uterus': 181.40704225352113, 'Vagina': 135.5601923076923}
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96.75, 97.27, 98.06, 97.72, 98.05, 98.35, 98.03, 97.82, 98.21, 98.29, 97.36, 97.37, 98.25, 97.76, 95.64, 95.49, 96.34, 94.63, 91.11, 87.29, 80.35, 72.34, 62.76, 56.84, 51.85, 48.81, 44.83, 43.5, 47.22, 40.92, 46.67, 47.46, 43.39, 46.33, 40.69, 42.65, 52.89, 43.64, 38.83, 42.26, 46.15, 46.67, 45.13, 48.09, 45.59, 42.92, 38.1, 40.04, 36.52, 37.42, 37.32, 40.55, 37.3, 37.56, 39.14, 38.46, 43.92, 35.97, 38.7, 41.17, 42.87, 41.79, 38.37, 41.44, 38.07, 42.81, 39.38, 35.4, 42.51, 35.67, 38.91, 38.89, 41.52, 33.04, 35.45, 38.38, 40.93, 55.16, 64.94, 72.87, 72.51, 75.05, 77.26, 82.36, 87.16, 88.79, 85.23, 89.27, 90.27, 91.58, 86.46, 88.46, 89.28, 86.58, 88.15, 87.68, 90.43, 82.82, 84.76, 82.79, 77.16, 80.49, 73.69, 67.04, 65.46, 53.35, 48.21, 45.3, 45.36, 39.29, 37.13, 39.27, 39.32, 38.09, 32.92, 38.45, 37.37, 35.3, 35.88, 41.54, 40.79, 36.69, 38.63, 37.9, 36.37, 36.39, 39.42, 37.84, 36.36, 45.47, 41.34, 37.76, 38.31, 40.72, 36.81, 39.35, 42.82, 40.32, 43.3, 44.42, 43.51, 38.48, 46.66, 39.88, 44.96, 44.97, 43.03, 51.26, 47.97, 41.74, 52.9, 38.17, 38.99, 39.81, 38.13, 32.07, 38.11, 34.16, 39.08, 36.31, 38.57, 36.98, 40.31, 40.92, 37.87, 40.27, 39.5, 42.89, 47.42, 36.31, 41.44, 38.05, 41.95, 45.35, 37.33, 37.88, 39.77, 38.41, 41.42, 42.61, 40.7, 44.82, 39.61, 37.35, 37.1, 40.27, 41.19, 40.85, 43.19, 41.94, 47.02, 39.7, 34.22, 44.36, 38.42, 36.4, 36.39, 32.73, 45.34, 56.89, 53.65, 55.44, 59.7, 66.03, 68.09, 71.21, 82.08, 86.77, 86.47, 91.09, 89.02, 89.18, 93.68, 93.99, 92.79, 92.81, 93.94, 92.86, 92.51, 94.13, 92.53, 89.77, 91.15, 90.14, 88.6, 86.69, 89.52, 90.9, 90.04, 89.77, 90.47, 92.62, 89.78, 88.82, 90.86, 89.88, 86.18, 87.44, 85.66, 85.15, 74.11, 71.62, 73.31, 66.34, 66.99, 68.73, 68.47, 66.5, 62.96, 67.15, 69.42, 73.69, 77.77, 82.7, 85.32, 83.67, 83.47, 87.85, 90.72, 91.1, 89.99, 93.26, 93.78, 94.12, 92.69, 94.74, 94.42, 93.2, 94.81, 94.92, 92.35, 91.45, 90.93, 88.64, 82.03, 62.76, 52.71, 49.63, 46.24, 45.09, 36.55, 36.62, 32.54, 41.23, 38.81, 35.56, 36.99, 40.12, 46.3, 49.53, 62.31, 66.09, 72.59, 69.52, 68.57, 74.46, 81.8, 76.68, 81.31, 84.4, 85.5, 80.93, 74.62, 80.56, 83.46, 77.53, 73.86, 72.78, 68.35, 61.81, 53.72, 53.19, 51.24, 43.89, 42.98, 36.87, 37.9, 43.16, 37.1, 38.34, 39.77, 35.77, 40.14, 38.49, 41.92, 42.44, 40.66, 37.6, 38.03, 39.01, 40.19, 38.75, 38.49, 38.85, 37.53, 37.29, 39.9, 38.08, 41.53, 39.45, 41.74, 43.44, 46.16, 42.76, 43.58, 43.68, 41.87, 45.1, 38.44, 44.51, 39.51, 40.23, 40.66, 38.75, 41.9, 43.21, 42.81, 46.79, 46.96, 53.94, 55.7, 53.35, 65.12, 61.05, 66.12, 64.02, 53.01, 56.92]
|
[1.0, 1.0, 1.0, 0.97, 0.99, 0.95, 0.99, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.93, 1.0, 0.94, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 1.0, 0.85, 0.94, 0.91, 0.75, 0.83, 0.78, 0.85, 0.84, 0.81, 0.71, 0.77, 0.41, 0.55, 0.96, 0.72, 0.27, 0.42, 0.26, 0.47, 0.31, 0.87, 0.92, 0.53, 0.72, 0.29, 0.33, 0.2, 0.02, 0.22, 0.08, 0.06, 0.3, 0.17, 0.0, 0.24, 0.59, 0.36, 0.01, 0.03, 0.58, 0.29, 0.0, 0.32, 0.69, 0.25, 0.77, 0.38, 0.0, 0.71, 0.36, 0.07, 0.34, 0.7, 0.48, 0.27, 0.33, 0.05, 0.47, 0.83, 0.62, 0.66, 0.24, 0.73, 0.41, 0.07, 0.3, 0.69, 0.51, 0.02, 0.79, 0.72, 0.28, 0.13, 0.02, 0.01, 0.1, 0.04, 0.0, 0.3, 0.51, 0.09, 0.1, 0.48, 0.55, 0.44, 0.24, 0.02, 0.44, 0.21, 0.0, 0.57, 0.34, 0.0, 0.23, 0.59, 0.13, 0.0, 0.39, 0.14, 0.04, 0.02, 0.46, 0.09, 0.05, 0.36, 0.58, 0.25, 0.25, 0.7, 0.83, 0.9, 0.36, 0.66, 0.29, 0.03, 0.57, 0.11, 0.0, 0.48, 0.28, 0.0, 0.31, 0.72, 0.22, 0.03, 0.6, 0.71, 0.37, 0.2, 0.73, 0.53, 0.1, 0.49, 0.82, 0.66, 0.39, 0.52, 0.6, 0.38, 0.84, 0.6, 0.79, 0.73, 0.84, 0.83, 0.93, 0.77, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.84, 1.0, 0.89, 1.0, 1.0, 1.0, 0.89, 0.95, 0.8, 0.85, 1.0, 1.0, 1.0, 1.0, 0.93, 0.99, 0.79, 1.0, 0.5, 0.83, 1.0, 0.96, 1.0, 0.97, 0.98, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 1.0, 0.97, 1.0, 1.0, 1.0, 0.96, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 0.98, 0.97, 0.99, 0.98, 1.0, 0.94, 1.0, 0.85, 0.99, 0.94, 0.99, 1.0, 1.0, 0.97, 1.0, 0.97, 0.89, 0.96, 0.84, 0.92, 0.92, 0.95, 0.92, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.95, 1.0, 0.93, 1.0, 0.9, 1.0, 0.99, 0.92, 0.99, 0.84, 1.0, 0.92, 0.96, 1.0, 0.98, 1.0, 1.0, 1.0, 0.95, 1.0, 0.96, 1.0, 1.0, 0.95, 0.83, 0.87, 0.75, 0.92, 0.91, 0.49, 0.91, 0.23, 0.38, 0.65, 0.16, 0.04, 0.45, 0.33, 0.0, 0.2, 0.48, 0.04, 0.03, 0.65, 0.2, 0.01, 0.35, 0.26, 0.9, 0.74, 0.03, 0.31, 0.79, 0.14, 0.0, 0.66, 0.37, 0.08, 0.25, 0.81, 0.64, 0.34, 0.55, 0.1, 0.87, 0.74, 0.63, 0.47, 0.27, 0.81, 0.4, 0.09, 0.54, 0.64, 0.35, 0.02, 0.7, 0.72, 0.47, 0.19, 0.03, 0.0, 0.31, 0.14, 0.0, 0.4, 0.53, 0.24, 0.04, 0.61, 0.6, 0.45, 0.51, 0.05, 0.83, 0.38, 0.0, 0.55, 0.35, 0.0, 0.01, 0.54, 0.1, 0.0, 0.39, 0.26, 0.03, 0.01, 0.46, 0.1, 0.06, 0.29, 0.64, 0.25, 0.22, 0.57, 0.83, 0.88, 0.45, 0.68, 0.26, 0.07, 0.56, 0.21, 0.0, 0.57, 0.52, 0.0, 0.24, 0.63, 0.19, 0.0, 0.34, 0.6, 0.41, 0.18, 0.68, 0.57, 0.13, 0.69, 0.76, 0.5, 0.73, 0.88, 0.84, 0.87, 0.7, 0.88, 0.81, 0.83, 0.78, 0.9, 0.87, 0.95, 0.93, 0.96, 0.9, 1.0, 1.0, 1.0, 1.0, 1.0, 0.79, 0.86, 0.62, 1.0, 1.0, 0.94, 1.0, 0.97, 0.99, 0.99, 0.96, 0.79, 0.74, 0.99, 0.75, 1.0, 0.83, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 0.99, 0.91, 0.99, 0.93, 0.85, 0.72, 0.5, 0.81, 0.82, 0.47, 0.73, 0.5, 0.66, 0.6, 0.57, 0.5, 0.52, 0.54, 0.6, 0.58, 0.5, 0.64, 0.66, 0.4, 0.49, 0.71, 0.7, 0.6, 0.56, 0.43, 0.6, 0.77, 0.75, 0.81, 0.55, 0.78, 0.79, 0.75, 0.81, 0.89, 0.93, 0.97, 1.0, 0.84, 1.0, 0.98, 0.79, 0.84, 0.95, 0.83, 0.97, 0.92, 0.89, 0.93, 0.99, 0.93, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.94, 0.98, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.91, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.98, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.8, 0.74, 0.76, 0.7, 0.71, 0.63, 0.34, 0.54, 0.69, 0.73, 0.1, 0.51, 0.75, 0.68, 0.33, 0.1, 0.6, 0.49, 0.05, 0.33, 0.49, 0.15, 0.13, 0.77, 0.58, 0.09, 0.55, 0.6, 0.89, 0.41, 0.38, 0.58, 0.49, 0.04, 0.27, 0.52, 0.09, 0.05, 0.27, 0.54, 0.41, 0.07, 0.58, 0.8, 0.28, 0.61, 0.93, 0.35, 0.52, 0.75, 0.92, 0.78, 0.33, 0.9, 0.33, 0.56, 0.18, 0.73, 0.68, 0.07, 0.44, 0.33, 0.32, 0.01, 0.02, 0.1, 0.34, 0.01, 0.26, 0.41, 0.19, 0.02, 0.46, 0.52, 0.37, 0.37, 0.73, 0.91, 0.87, 0.86, 0.94, 0.92, 0.89, 0.87, 0.93, 0.83, 0.99, 1.0, 0.97, 0.99, 0.98, 0.59, 0.61, 0.87, 0.75, 0.39, 0.61, 0.51, 0.65, 0.5, 0.68, 0.66, 0.73, 0.51, 0.63, 0.56, 0.55, 0.57, 0.67, 0.7, 0.5, 0.6, 0.56, 0.54, 0.75, 0.81, 0.86, 0.8, 0.97, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.99]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 64.473146
| 0.706854
| 798
|
O43791
|
P35226
|
nan, 15897469, E3Net
|
degron_data, UbiNet, UbiBrowser, 31181401
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
BMI1
|
MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQRDGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSPSGNHQSSFANRPRKSSVNGSSATSSG
|
Homo sapiens
|
Nucleus, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '14.1', 'Basal respiratory cells': '12.3', 'Club cells': '15.6', 'Ionocytes': '9.2', 'Mucus glandular cells': '19.5', 'Serous glandular cells': '15.3', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '4.8', 'Paneth cells': '11.5', 'Distal enterocytes': '7.7', 'Intestinal goblet cells': '9.6', 'Exocrine glandular cells': '-0.664', 'Basal prostatic cells': '20.4', 'Prostatic glandular cells': '33.5', 'Breast glandular cells': '0.474', 'Breast myoepithelial cells': '0.315', 'Glandular and luminal cells': '10.0', 'Secretory cells': '9.2', 'Basal keratinocytes': '11.8', 'Suprabasal keratinocytes': '10.9', 'Basal squamous epithelial cells': '14.8', 'Squamous epithelial cells': '10.8', 'Alveolar cells type 1': '0.123', 'Alveolar cells type 2': '-0.155', 'Salivary duct cells': '12.3', 'Ductal cells': '0.553', 'Hepatocytes': '0.480', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.111', 'Distal tubular cells': '12.3', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.254', 'Sertoli cells': '0.011', 'Granulosa cells': '12.8', 'Enteroendocrine cells': '10.6', 'Pancreatic endocrine cells': '13.6', 'Leydig cells': '-0.012', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '14.2', 'Bipolar cells': '16.8', 'Horizontal cells': '13.2', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '12.9', 'Schwann cells': '0.135', 'Spermatogonia': '0.349', 'Spermatocytes': '0.375', 'Early spermatids': '0.312', 'Late spermatids': '0.164', 'Oocytes': '2.2', 'Cytotrophoblasts': '12.7', 'Syncytiotrophoblasts': '6.7', 'Extravillous trophoblasts': '22.9', 'Endothelial cells': '23.3', 'Lymphatic endothelial cells': '16.9', 'Cardiomyocytes': '0.525', 'Skeletal myocytes': '-0.239', 'Smooth muscle cells': '22.2', 'Adipocytes': '20.6', 'Melanocytes': '-0.095', 'Fibroblasts': '21.6', 'Peritubular cells': '0.082', 'Endometrial stromal cells': '23.3', 'Ovarian stromal cells': '11.8', 'Undifferentiated cells': '10.9', 'T-cells': '22.4', 'B-cells': '23.0', 'Plasma cells': '42.4', 'Nk-cells': '19.6', 'Granulocytes': '40.2', 'Monocytes': '21.9', 'Macrophages': '15.0', 'Hofbauer cells': '10.1', 'Kupffer cells': '25.7', 'Dendritic cells': '10.1', 'Langerhans cells': '0.073', 'Erythroid cells': '-0.067', 'Adipocytes (Subcutaneous)': '-0.306', 'Adipocytes (Visceral)': '-0.173', 'Breast glandular cells (progenitors)': '0.329', 'Adipocytes (Breast)': '-0.239', 'Colon enterocytes': '-0.156', 'Colon enteroendocrine cells': '0.289', 'Enteric glia cells': '0.072', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.499', 'Podocytes': '0.048', 'Ascending Loop of Henle cells': '0.443', 'Intercalated cells': '0.100', 'Cholangiocyte': '0.305', 'NK-cells (Liver)': '-0.230', 'Respiratory ciliated cells': '0.085', 'Mitotic cells (Lung)': '-0.089', 'NK-cells (Lung)': '0.065', 'B-cells (Lung)': '-0.042', 'Alpha cells': '0.433', 'Beta cells': '0.254', 'Prostate glandular cells': '-0.052', 'Prostate basal glandular cells': '0.170', 'Urothelial cells': '0.098', 'Keratinocyte (other)': '-0.212', 'Keratinocyte (granular)': '-0.292', 'Hair cortex cells': '0.087', 'Inner root sheath cells': '0.148', 'Outer root sheath cells': '0.296', 'Sebaceous gland cells': '0.164', 'Eccrine sweat gland cells': '0.468', 'Adipocytes (Skin)': '0.241', 'Mitotic cells (Skin)': '0.173', 'Parietal cells': '-0.642', 'Chief cells': '-0.512', 'Gastric mucous cells': '-0.541', 'Gastric enteroendocrine cells': '-0.392', 'Mitotic cells (Stomach)': '-0.093', 'Parafollicular cells': '-0.002', 'Thyroid glandular cells': '0.298', 'Mitotic cells (Thyroid)': '0.092', 'Adrenal cortex cells': '0.476', 'Adrenal medulla cells': '-0.038', 'Mitotic cells (Adrenal gland)': '0.258', 'Minor salivary glandular cells': '0.620', 'Minor salivary gland ductal cells': '0.347', 'Minor salivary gland basal cells': '-0.035', 'Mitotic cells (Minor salivary gland)': '0.010', 'Adipocytes (Minor salivary gland)': '0.119', 'Somatotropes': '0.144', 'Lactotropes': '0.027', 'Gonadotropes': '0.012', 'Corticotropes': '-0.068', 'Thyrotropes': '0.172', 'Undifferentiated cells (Pituitary gland)': '0.251', 'Mitotic cells (Spleen)': '-0.282', 'Platelets': '-0.188', 'Erythrocytes': '-0.207', 'Hematopoietic stem cells': '-0.349', 'B-cells (Spleen)': '0.346', 'NK-cells (Spleen)': '0.315', 'Amygdala excitatory': '14.9', 'Cerebellar inhibitory': '13.6', 'Cge interneuron': '21.1', 'Deep-layer corticothalamic and 6b': '12.3', 'Deep-layer intratelencephalic': '14.5', 'Deep-layer near-projecting': '14.3', 'Eccentric medium spiny neuron': '27.4', 'Hippocampal ca1-3': '13.0', 'Hippocampal ca4': '17.2', 'Hippocampal dentate gyrus': '20.0', 'Lamp5-lhx6 and chandelier': '19.4', 'Lower rhombic lip': '4.3', 'Mammillary body': '13.6', 'Medium spiny neuron': '20.5', 'Mge interneuron': '14.9', 'Midbrain-derived inhibitory': '19.9', 'Miscellaneous': '13.2', 'Splatter': '14.1', 'Thalamic excitatory': '13.0', 'Upper rhombic lip': '22.1', 'Upper-layer intratelencephalic': '14.4', 'Astrocyte': '12.3', 'Bergmann glia': '11.1', 'Central nervous system macrophage': '32.9', 'Choroid plexus epithelial cell': '17.7', 'Committed oligodendrocyte precursor': '28.1', 'Ependymal cell': '23.7', 'Oligodendrocyte': '48.2', 'Oligodendrocyte precursor cell': '26.6', 'Endothelial cell': '13.0', 'Pericyte': '30.6', 'Vascular associated smooth muscle cell': '19.3', 'Fibroblast': '21.5', 'Leukocyte': '24.8', 'Basophil': '29.1', 'Eosinophil': '2.5', 'Neutrophil': '4.0', 'Classical monocyte': '13.3', 'Non-classical monocyte': '41.9', 'Intermediate monocyte': '20.0', 'T-reg': '25.6', 'GdT-cell': '5.2', 'MAIT T-cell': '46.5', 'Memory CD4 T-cell': '5.4', 'Naive CD4 T-cell': '49.6', 'Memory CD8 T-cell': '5.0', 'Naive CD8 T-cell': '43.5', 'Memory B-cell': '4.4', 'Naive B-cell': '52.1', 'Plasmacytoid DC': '14.5', 'Myeloid DC': '12.2', 'NK-cell': '36.6', 'Total PBMC': '19.7', 'Vd2 gdTCR': '34.5', 'Memory CD4 T-cell Th1\\/Th17': '102.8', 'Memory CD4 T-cell Th17': '47.6', 'Memory CD4 T-cell Th2': '53.4', 'Non-Vd2 gdTCR': '49.3', 'Memory CD4 T-cell Th1': '49.8', 'Memory CD4 T-cell TFH': '34.5', 'Terminal effector memory CD4 T-cell': '50.9', 'Central memory CD8 T-cell': '34.6', 'Effector memory CD8 T-cell': '37.3', 'Terminal effector memory CD8 T-cell': '37.9', 'Non-switched memory B-cell': '26.0', 'Plasmablast': '28.6', 'Switched memory B-cell': '38.2', 'Exhausted memory B-cell': '29.4', 'Progenitor cell': '26.8', 'Memory T-reg': '22.3', 'Naive CD4 T-cell activated': '127.8', 'Naive CD8 T-cell activated': '67.3', 'Naive T-reg': '66.4'}
|
2H0D, 2NA1, 3RPG, 4R8P, 5FR6, 6WI7, 6WI8, 7ND1, 8GRM, 8PP7
|
{'Adipose Tissue': 34.884422757475086, 'Adrenal Gland': 31.10723643410853, 'Bladder': 44.16619047619048, 'Blood': 10.619844262648009, 'Blood Vessel': 56.23349812734082, 'Brain': 29.833904996214983, 'Breast': 33.93374727668845, 'Cervix Uteri': 50.83736842105263, 'Colon': 40.07144929396662, 'Esophagus': 33.74332456747405, 'Fallopian Tube': 42.94777777777778, 'Heart': 12.494699303135889, 'Kidney': 17.86291011235955, 'Liver': 14.9484203539823, 'Lung': 35.617695501730104, 'Muscle': 25.506378580323783, 'Nerve': 55.93058158319871, 'Ovary': 34.932, 'Pancreas': 12.877051829268291, 'Pituitary': 52.59858657243816, 'Prostate': 40.08391836734694, 'Salivary Gland': 27.11483950617284, 'Skin': 29.48179988944168, 'Small Intestine': 30.15028877005348, 'Spleen': 38.41788381742738, 'Stomach': 26.254646239554315, 'Testis': 48.35249307479224, 'Thyroid': 34.93742725880551, 'Uterus': 53.12598591549296, 'Vagina': 32.246153846153845}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[39.48, 55.93, 61.09, 69.51, 81.24, 85.47, 91.9, 94.64, 94.39, 96.24, 96.59, 96.43, 97.26, 96.89, 97.48, 98.33, 98.48, 98.78, 98.27, 98.57, 98.43, 98.03, 98.34, 98.62, 98.73, 98.18, 97.44, 98.64, 98.83, 98.81, 98.7, 98.1, 97.8, 98.21, 98.2, 98.72, 98.77, 98.85, 98.83, 98.5, 97.8, 98.77, 98.63, 98.46, 98.32, 98.63, 98.31, 97.47, 96.66, 97.5, 97.74, 98.56, 98.65, 98.3, 98.31, 98.41, 98.03, 98.29, 98.22, 98.31, 97.73, 96.0, 95.4, 96.7, 97.13, 97.57, 97.28, 97.65, 98.59, 98.51, 98.21, 98.29, 96.11, 96.45, 98.03, 97.38, 94.4, 95.22, 96.86, 94.85, 92.17, 93.31, 94.58, 91.72, 91.75, 94.84, 92.93, 91.11, 94.53, 96.07, 93.46, 94.3, 95.74, 94.58, 93.11, 94.81, 93.77, 90.43, 90.91, 92.49, 89.69, 83.28, 77.33, 71.11, 62.62, 58.55, 58.42, 67.98, 73.59, 83.58, 85.0, 84.99, 86.82, 86.58, 89.18, 85.02, 82.15, 75.0, 70.32, 67.16, 68.21, 74.99, 77.85, 85.8, 88.98, 86.53, 86.16, 85.4, 90.51, 94.58, 94.27, 95.97, 97.69, 97.31, 97.05, 95.42, 94.63, 92.33, 82.86, 75.62, 70.06, 71.07, 64.9, 63.24, 62.2, 59.26, 56.54, 56.3, 56.39, 55.21, 50.63, 49.83, 43.73, 43.93, 46.33, 49.65, 48.17, 60.67, 67.9, 85.46, 92.69, 94.85, 96.95, 97.07, 97.07, 96.45, 96.67, 95.47, 95.21, 96.56, 97.4, 98.01, 97.71, 98.04, 97.87, 97.61, 97.64, 97.4, 97.17, 97.42, 97.14, 95.75, 93.97, 96.39, 95.7, 96.14, 94.15, 95.3, 95.8, 95.2, 96.9, 97.12, 98.01, 97.7, 96.71, 92.0, 91.43, 95.21, 96.7, 97.76, 96.69, 96.74, 95.26, 96.77, 96.58, 97.26, 94.54, 94.79, 96.43, 94.77, 92.79, 94.31, 94.63, 92.57, 92.63, 88.74, 89.4, 88.41, 92.13, 95.53, 96.64, 96.67, 97.93, 97.13, 97.27, 95.4, 95.23, 93.24, 93.29, 87.11, 72.08, 61.25, 54.47, 50.03, 45.91, 46.32, 42.31, 45.06, 42.44, 43.75, 41.24, 42.68, 45.47, 38.01, 39.2, 42.02, 39.5, 41.71, 50.42, 41.38, 52.05, 40.84, 57.59, 43.64, 49.82, 52.43, 45.99, 42.31, 44.81, 44.9, 50.01, 40.68, 41.24, 40.42, 45.84, 49.79, 46.78, 42.65, 54.36, 52.37, 40.79, 56.94, 47.24, 50.24, 45.22, 42.33, 48.93, 37.05, 45.31, 37.39, 45.22, 42.75, 41.86, 47.47, 36.92, 44.81, 44.41, 34.87, 40.36, 37.07, 33.12, 37.45, 42.68, 40.61, 33.62, 40.48, 38.86, 42.33, 39.87, 41.64, 42.57, 47.93, 43.9, 48.18, 43.44, 48.37, 40.41, 45.32, 45.68, 40.64, 47.79, 44.17, 43.36, 48.57, 40.34, 56.99, 54.98, 42.16, 48.67, 49.85, 49.36, 52.17, 55.66, 53.71, 59.95, 65.51]
|
[0.84, 0.77, 0.78, 0.87, 0.86, 0.95, 0.6, 0.69, 0.32, 0.65, 0.56, 0.25, 0.17, 0.74, 0.73, 0.03, 0.39, 0.01, 0.64, 0.35, 0.55, 0.63, 0.36, 0.29, 0.04, 0.26, 0.33, 0.03, 0.03, 0.11, 0.0, 0.44, 0.6, 0.23, 0.7, 0.26, 0.2, 0.0, 0.04, 0.46, 0.61, 0.21, 0.0, 0.33, 0.7, 0.3, 0.06, 0.69, 0.87, 0.2, 0.42, 0.48, 0.0, 0.3, 0.51, 0.41, 0.69, 0.39, 0.42, 0.0, 0.29, 0.78, 0.69, 0.67, 0.07, 0.51, 0.41, 0.16, 0.15, 0.56, 0.74, 0.29, 0.46, 0.65, 0.16, 0.08, 0.24, 0.45, 0.0, 0.07, 0.5, 0.44, 0.06, 0.81, 0.27, 0.14, 0.12, 0.45, 0.54, 0.15, 0.05, 0.5, 0.67, 0.12, 0.48, 0.47, 0.55, 0.35, 0.7, 0.75, 0.46, 0.74, 0.9, 0.34, 0.69, 0.42, 0.86, 0.85, 0.41, 0.46, 0.53, 0.41, 0.37, 0.16, 0.08, 0.55, 0.2, 0.54, 0.5, 0.65, 0.64, 0.33, 0.56, 0.15, 0.06, 0.18, 0.63, 0.7, 0.22, 0.58, 0.01, 0.4, 0.0, 0.08, 0.04, 0.27, 0.48, 0.08, 0.34, 0.51, 0.62, 0.5, 0.36, 0.59, 0.74, 0.77, 0.79, 0.85, 0.61, 0.89, 0.89, 0.84, 0.97, 0.72, 0.98, 0.93, 0.99, 0.71, 0.62, 0.55, 0.38, 0.6, 0.55, 0.25, 0.85, 0.05, 0.43, 0.0, 0.48, 0.3, 0.13, 0.0, 0.43, 0.46, 0.02, 0.17, 0.59, 0.45, 0.04, 0.33, 0.78, 0.67, 0.49, 0.81, 0.13, 0.53, 0.68, 0.62, 0.38, 0.43, 0.03, 0.13, 0.01, 0.0, 0.14, 0.67, 0.65, 0.52, 0.4, 0.07, 0.4, 0.41, 0.53, 0.28, 0.2, 0.0, 0.27, 0.36, 0.0, 0.04, 0.31, 0.57, 0.26, 0.69, 0.16, 0.75, 0.19, 0.71, 0.53, 0.35, 0.0, 0.46, 0.02, 0.23, 0.12, 0.27, 0.33, 0.39, 0.69, 0.31, 0.86, 0.8, 0.93, 0.87, 0.92, 0.8, 0.85, 0.88, 0.88, 0.97, 0.9, 0.97, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.99, 0.92, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.96, 0.98, 0.92, 0.99, 0.9, 0.93, 0.92, 0.76, 0.92, 0.89, 0.88, 0.87, 0.93, 0.76, 0.98, 0.93, 0.99, 0.92, 0.97, 0.95, 1.0, 0.99, 1.0, 1.0, 1.0, 0.97, 0.98, 0.98, 0.98, 0.98, 0.99, 1.0, 1.0, 0.97, 1.0, 0.97, 1.0, 1.0, 0.96, 1.0, 0.93, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 76.713344
| 0.577086
| 2,278
|
O43791
|
P35659
|
nan, 25278611, nan
|
degron_data, UbiNet, UbiBrowser, 31181401, DegPred, degron_data
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
DEK
|
MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLTERKDFIKTTVKELIS
|
Homo sapiens
|
Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '121.4', 'Basal respiratory cells': '122.1', 'Club cells': '141.2', 'Ionocytes': '46.0', 'Mucus glandular cells': '227.3', 'Serous glandular cells': '139.0', 'Gastric mucus-secreting cells': '87.3', 'Proximal enterocytes': '131.2', 'Paneth cells': '109.1', 'Distal enterocytes': '92.5', 'Intestinal goblet cells': '137.9', 'Exocrine glandular cells': '-0.652', 'Basal prostatic cells': '136.4', 'Prostatic glandular cells': '181.0', 'Breast glandular cells': '0.400', 'Breast myoepithelial cells': '0.501', 'Glandular and luminal cells': '181.7', 'Secretory cells': '200.6', 'Basal keratinocytes': '294.2', 'Suprabasal keratinocytes': '227.8', 'Basal squamous epithelial cells': '160.2', 'Squamous epithelial cells': '149.5', 'Alveolar cells type 1': '0.205', 'Alveolar cells type 2': '-0.315', 'Salivary duct cells': '207.1', 'Ductal cells': '0.596', 'Hepatocytes': '0.356', 'Cholangiocytes': '166.0', 'Proximal tubular cells': '0.119', 'Distal tubular cells': '83.0', 'Collecting duct cells': '79.7', 'Mesothelial cells': '0.381', 'Sertoli cells': '0.499', 'Granulosa cells': '142.2', 'Enteroendocrine cells': '112.8', 'Pancreatic endocrine cells': '112.1', 'Leydig cells': '0.640', 'Excitatory neurons': '10.0', 'Inhibitory neurons': '17.8', 'Cone photoreceptor cells': '193.7', 'Rod photoreceptor cells': '127.8', 'Bipolar cells': '63.3', 'Horizontal cells': '27.1', 'Astrocytes': '15.5', 'Oligodendrocyte precursor cells': '24.5', 'Oligodendrocytes': '34.6', 'Microglial cells': '30.4', 'Muller glia cells': '120.0', 'Schwann cells': '0.134', 'Spermatogonia': '0.656', 'Spermatocytes': '0.311', 'Early spermatids': '-0.369', 'Late spermatids': '-0.687', 'Oocytes': '158.1', 'Cytotrophoblasts': '301.5', 'Syncytiotrophoblasts': '113.8', 'Extravillous trophoblasts': '236.1', 'Endothelial cells': '168.6', 'Lymphatic endothelial cells': '232.5', 'Cardiomyocytes': '0.570', 'Skeletal myocytes': '-0.095', 'Smooth muscle cells': '195.5', 'Adipocytes': '157.9', 'Melanocytes': '0.093', 'Fibroblasts': '165.7', 'Peritubular cells': '0.548', 'Endometrial stromal cells': '161.4', 'Ovarian stromal cells': '175.5', 'Undifferentiated cells': '284.2', 'T-cells': '213.5', 'B-cells': '164.2', 'Plasma cells': '21.9', 'Nk-cells': '233.4', 'Granulocytes': '194.9', 'Monocytes': '225.7', 'Macrophages': '245.8', 'Hofbauer cells': '191.4', 'Kupffer cells': '165.2', 'Dendritic cells': '125.2', 'Langerhans cells': '0.130', 'Erythroid cells': '-0.003', 'Adipocytes (Subcutaneous)': '-0.452', 'Adipocytes (Visceral)': '-0.471', 'Breast glandular cells (progenitors)': '0.360', 'Adipocytes (Breast)': '-0.491', 'Colon enterocytes': '-0.165', 'Colon enteroendocrine cells': '0.288', 'Enteric glia cells': '-0.015', 'Mitotic cells (Colon)': '-0.135', 'Mitotic cells (Heart)': '0.489', 'Podocytes': '0.092', 'Ascending Loop of Henle cells': '0.362', 'Intercalated cells': '0.066', 'Cholangiocyte': '0.277', 'NK-cells (Liver)': '-0.188', 'Respiratory ciliated cells': '0.114', 'Mitotic cells (Lung)': '-0.060', 'NK-cells (Lung)': '0.420', 'B-cells (Lung)': '0.234', 'Alpha cells': '0.364', 'Beta cells': '0.163', 'Prostate glandular cells': '-0.193', 'Prostate basal glandular cells': '0.100', 'Urothelial cells': '0.062', 'Keratinocyte (other)': '0.002', 'Keratinocyte (granular)': '-0.272', 'Hair cortex cells': '0.043', 'Inner root sheath cells': '0.155', 'Outer root sheath cells': '0.309', 'Sebaceous gland cells': '0.042', 'Eccrine sweat gland cells': '0.195', 'Adipocytes (Skin)': '-0.015', 'Mitotic cells (Skin)': '0.314', 'Parietal cells': '-0.695', 'Chief cells': '-0.582', 'Gastric mucous cells': '-0.408', 'Gastric enteroendocrine cells': '-0.430', 'Mitotic cells (Stomach)': '0.055', 'Parafollicular cells': '0.146', 'Thyroid glandular cells': '0.544', 'Mitotic cells (Thyroid)': '-0.102', 'Adrenal cortex cells': '0.554', 'Adrenal medulla cells': '0.034', 'Mitotic cells (Adrenal gland)': '0.302', 'Minor salivary glandular cells': '0.530', 'Minor salivary gland ductal cells': '0.049', 'Minor salivary gland basal cells': '0.395', 'Mitotic cells (Minor salivary gland)': '0.451', 'Adipocytes (Minor salivary gland)': '0.141', 'Somatotropes': '-0.033', 'Lactotropes': '-0.077', 'Gonadotropes': '-0.074', 'Corticotropes': '-0.238', 'Thyrotropes': '0.067', 'Undifferentiated cells (Pituitary gland)': '0.289', 'Mitotic cells (Spleen)': '-0.153', 'Platelets': '-0.146', 'Erythrocytes': '-0.100', 'Hematopoietic stem cells': '-0.178', 'B-cells (Spleen)': '0.313', 'NK-cells (Spleen)': '0.312', 'Amygdala excitatory': '10.7', 'Cerebellar inhibitory': '29.0', 'Cge interneuron': '32.2', 'Deep-layer corticothalamic and 6b': '12.3', 'Deep-layer intratelencephalic': '14.7', 'Deep-layer near-projecting': '10.1', 'Eccentric medium spiny neuron': '17.0', 'Hippocampal ca1-3': '9.1', 'Hippocampal ca4': '7.9', 'Hippocampal dentate gyrus': '12.5', 'Lamp5-lhx6 and chandelier': '20.9', 'Lower rhombic lip': '15.8', 'Mammillary body': '12.4', 'Medium spiny neuron': '10.8', 'Mge interneuron': '27.4', 'Midbrain-derived inhibitory': '23.1', 'Miscellaneous': '21.7', 'Splatter': '18.3', 'Thalamic excitatory': '14.3', 'Upper rhombic lip': '76.8', 'Upper-layer intratelencephalic': '15.7', 'Astrocyte': '44.4', 'Bergmann glia': '69.5', 'Central nervous system macrophage': '106.1', 'Choroid plexus epithelial cell': '45.0', 'Committed oligodendrocyte precursor': '45.2', 'Ependymal cell': '86.1', 'Oligodendrocyte': '70.0', 'Oligodendrocyte precursor cell': '60.6', 'Endothelial cell': '59.6', 'Pericyte': '90.1', 'Vascular associated smooth muscle cell': '77.0', 'Fibroblast': '52.0', 'Leukocyte': '107.8', 'Basophil': '100.0', 'Eosinophil': '41.9', 'Neutrophil': '137.4', 'Classical monocyte': '126.8', 'Non-classical monocyte': '184.9', 'Intermediate monocyte': '138.2', 'T-reg': '114.5', 'GdT-cell': '69.9', 'MAIT T-cell': '131.7', 'Memory CD4 T-cell': '72.8', 'Naive CD4 T-cell': '129.6', 'Memory CD8 T-cell': '78.0', 'Naive CD8 T-cell': '101.0', 'Memory B-cell': '66.7', 'Naive B-cell': '110.8', 'Plasmacytoid DC': '92.9', 'Myeloid DC': '166.4', 'NK-cell': '142.6', 'Total PBMC': '124.9', 'Vd2 gdTCR': '147.1', 'Memory CD4 T-cell Th1\\/Th17': '190.1', 'Memory CD4 T-cell Th17': '151.5', 'Memory CD4 T-cell Th2': '151.4', 'Non-Vd2 gdTCR': '149.6', 'Memory CD4 T-cell Th1': '133.6', 'Memory CD4 T-cell TFH': '126.2', 'Terminal effector memory CD4 T-cell': '140.3', 'Central memory CD8 T-cell': '130.2', 'Effector memory CD8 T-cell': '192.1', 'Terminal effector memory CD8 T-cell': '149.0', 'Non-switched memory B-cell': '105.4', 'Plasmablast': '7.7', 'Switched memory B-cell': '115.0', 'Exhausted memory B-cell': '120.0', 'Progenitor cell': '104.2', 'Memory T-reg': '105.8', 'Naive CD4 T-cell activated': '199.0', 'Naive CD8 T-cell activated': '154.0', 'Naive T-reg': '146.3'}
|
1Q1V, 2JX3
|
{'Adipose Tissue': 65.07479069767442, 'Adrenal Gland': 33.71001937984496, 'Bladder': 69.61380952380952, 'Blood': 47.074575672766414, 'Blood Vessel': 82.78313857677902, 'Brain': 25.874077592732775, 'Breast': 66.12514161220044, 'Cervix Uteri': 82.80368421052631, 'Colon': 74.30491655969192, 'Esophagus': 63.05444982698962, 'Fallopian Tube': 75.7811111111111, 'Heart': 22.70078745644599, 'Kidney': 25.618325842696628, 'Liver': 18.863778761061948, 'Lung': 70.74126297577854, 'Muscle': 43.098153175591534, 'Nerve': 72.1859127625202, 'Ovary': 68.90583333333333, 'Pancreas': 16.050176829268292, 'Pituitary': 32.87720848056537, 'Prostate': 58.33444897959184, 'Salivary Gland': 50.06944444444444, 'Skin': 71.01213377556661, 'Small Intestine': 65.56598930481283, 'Spleen': 45.15730290456432, 'Stomach': 41.58927576601671, 'Testis': 21.542686980609417, 'Thyroid': 100.32235834609494, 'Uterus': 95.32218309859157, 'Vagina': 73.77301282051282}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[52.79, 51.76, 53.3, 53.36, 66.2, 63.06, 59.37, 62.99, 57.61, 56.53, 51.35, 46.63, 62.19, 50.2, 47.11, 50.79, 52.72, 45.96, 51.59, 49.92, 50.42, 52.92, 51.07, 50.27, 55.41, 51.97, 44.47, 47.67, 44.94, 42.25, 40.21, 42.28, 39.81, 43.99, 42.12, 44.84, 39.39, 44.29, 41.96, 45.05, 44.38, 45.54, 44.11, 45.06, 45.95, 47.38, 46.64, 50.87, 48.95, 49.64, 46.87, 48.93, 48.64, 51.02, 55.94, 61.97, 57.59, 53.66, 65.55, 63.66, 68.41, 72.42, 70.13, 73.14, 68.85, 69.06, 64.07, 60.52, 59.8, 61.91, 51.79, 54.12, 49.76, 48.05, 54.2, 56.26, 55.96, 60.35, 58.55, 65.55, 64.01, 69.11, 68.73, 68.05, 75.14, 78.7, 84.99, 83.95, 80.24, 81.6, 81.39, 80.96, 79.16, 82.77, 84.02, 84.98, 83.92, 84.8, 84.84, 83.63, 81.95, 83.02, 84.35, 84.23, 86.01, 86.9, 86.92, 87.07, 86.95, 87.82, 86.0, 84.68, 83.91, 82.37, 84.03, 82.16, 79.85, 75.82, 82.67, 83.96, 82.94, 82.92, 86.19, 85.67, 85.45, 86.11, 85.4, 85.74, 84.08, 84.74, 80.25, 82.82, 78.74, 78.74, 79.18, 76.07, 75.07, 76.78, 86.16, 85.58, 84.17, 86.44, 87.75, 87.66, 86.55, 89.06, 89.71, 86.28, 88.2, 88.65, 88.24, 86.31, 88.72, 87.17, 88.75, 87.15, 89.71, 88.22, 88.26, 87.9, 87.43, 86.3, 84.64, 83.33, 82.88, 82.89, 83.55, 84.37, 81.84, 80.6, 87.67, 86.46, 88.56, 89.61, 89.46, 89.77, 88.51, 87.54, 89.24, 86.25, 86.31, 84.84, 82.99, 78.55, 68.27, 73.41, 67.59, 63.39, 56.69, 54.7, 57.12, 54.66, 60.09, 59.15, 53.07, 50.62, 43.23, 42.37, 40.1, 37.21, 47.57, 39.32, 43.07, 43.85, 48.95, 43.07, 41.86, 49.32, 42.76, 50.9, 48.35, 45.04, 49.9, 48.27, 53.61, 49.84, 50.86, 51.33, 51.09, 47.45, 49.75, 40.24, 47.44, 41.15, 46.62, 48.68, 39.04, 45.6, 43.94, 39.0, 40.68, 40.48, 45.99, 48.32, 51.25, 53.12, 52.51, 49.01, 47.43, 47.55, 42.74, 41.56, 42.22, 43.6, 45.01, 48.36, 50.42, 48.82, 53.07, 45.02, 47.33, 43.64, 43.17, 45.08, 46.94, 49.43, 44.12, 47.32, 48.6, 48.36, 45.55, 48.29, 48.56, 46.37, 44.85, 40.43, 49.1, 44.17, 44.95, 48.36, 50.81, 46.95, 49.77, 47.59, 44.34, 50.24, 45.1, 49.65, 49.66, 46.24, 51.18, 50.07, 58.46, 46.11, 55.19, 45.6, 56.41, 54.46, 53.72, 47.96, 50.38, 52.83, 44.33, 50.5, 45.18, 48.68, 48.86, 46.69, 50.09, 45.11, 48.25, 45.0, 43.51, 49.41, 44.85, 42.77, 49.95, 54.4, 47.63, 61.81, 52.78, 54.95, 50.13, 53.96, 55.49, 57.85, 63.24, 70.63, 74.77, 79.59, 84.68, 88.34, 89.0, 90.97, 90.04, 90.26, 91.87, 91.43, 91.21, 90.59, 91.47, 89.31, 88.63, 88.1, 85.06, 82.02, 83.34, 80.22, 77.62, 81.01, 82.55, 86.99, 85.18, 87.3, 89.65, 89.38, 88.71, 89.61, 90.63, 90.79, 89.9, 90.97, 88.18, 87.94, 85.58, 84.27, 79.87, 85.99, 84.07, 82.52, 85.79, 84.95, 88.14, 91.03, 91.56, 91.11, 90.24, 93.25, 91.76, 90.62, 89.45, 91.02, 86.76, 84.18, 80.82]
|
[1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.97, 1.0, 0.96, 1.0, 0.97, 0.97, 0.99, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 1.0, 0.92, 0.97, 1.0, 0.86, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.98, 0.99, 0.94, 0.88, 0.84, 0.82, 0.96, 0.93, 0.67, 0.78, 0.91, 0.69, 0.81, 0.75, 0.92, 0.74, 0.99, 0.93, 0.91, 0.92, 0.91, 0.7, 0.99, 0.95, 0.96, 0.97, 0.9, 0.91, 0.86, 0.89, 0.85, 0.89, 0.72, 0.79, 0.77, 0.71, 0.7, 0.76, 0.79, 0.86, 0.83, 0.79, 0.78, 0.31, 0.79, 0.3, 0.55, 0.73, 0.2, 0.63, 0.42, 0.33, 0.33, 0.01, 0.43, 0.52, 0.06, 0.61, 0.18, 0.02, 0.38, 0.32, 0.18, 0.01, 0.5, 0.69, 0.25, 0.72, 0.37, 0.5, 0.24, 0.08, 0.48, 0.24, 0.01, 0.02, 0.58, 0.03, 0.05, 0.23, 0.55, 0.33, 0.93, 0.21, 0.67, 0.53, 0.74, 0.38, 0.0, 0.41, 0.72, 0.12, 0.0, 0.05, 0.41, 0.02, 0.06, 0.0, 0.07, 0.52, 0.13, 0.69, 0.79, 0.57, 0.34, 0.77, 0.55, 0.2, 0.61, 0.65, 0.1, 0.27, 0.52, 0.42, 0.0, 0.56, 0.71, 0.17, 0.75, 0.47, 0.4, 0.28, 0.0, 0.43, 0.19, 0.03, 0.01, 0.2, 0.02, 0.01, 0.16, 0.19, 0.66, 0.47, 0.5, 0.56, 0.62, 0.32, 0.57, 0.46, 0.0, 0.03, 0.66, 0.31, 0.0, 0.02, 0.58, 0.11, 0.01, 0.12, 0.48, 0.04, 0.7, 0.59, 0.43, 0.79, 0.53, 0.81, 0.41, 0.4, 0.86, 0.76, 0.89, 0.82, 0.83, 0.79, 0.85, 0.96, 0.9, 1.0, 0.99, 0.92, 1.0, 0.93, 1.0, 1.0, 1.0, 1.0, 0.96, 0.98, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.78, 1.0, 0.8, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.99, 0.87, 0.99, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.95, 0.99, 0.92, 0.99, 0.92, 0.99, 0.89, 1.0, 0.94, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.87, 0.98, 0.76, 0.81, 0.97, 0.74, 0.94, 0.93, 0.77, 0.85, 0.75, 0.65, 0.03, 0.5, 0.4, 0.76, 0.46, 0.0, 0.35, 0.67, 0.17, 0.0, 0.66, 0.72, 0.13, 0.09, 0.79, 0.71, 0.28, 0.61, 0.53, 0.97, 0.63, 0.11, 0.5, 0.44, 0.75, 0.39, 0.0, 0.13, 0.61, 0.31, 0.0, 0.35, 0.73, 0.62, 0.17, 0.76, 0.96, 0.32, 0.82, 0.03, 0.57, 0.95, 0.26, 0.42, 0.51, 0.35, 0.0, 0.39, 0.61, 0.03, 0.01, 0.67, 0.61, 0.41, 0.42, 0.78]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 65.33112
| 0.68312
| 2,072
|
O43791
|
P49327
|
30955223
|
UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
FASN
|
MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRFDASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEALSRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQCPAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLARRVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHGTGTKVGDPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNTQPPPAPAPHATLPRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGERGGPEVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLSTDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAVLAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFEFVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPEAQWHSSLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCTIIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSLAWDVPAAEDFPNGSGSPSAAIYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLARALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQWDDPDPRLFDHPESPTPNPTEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRLLWKDNWVSFMDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVVSRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHTEEGCLSERAALQEELQLCKGLVQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQVLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLLSPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVAALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSTEPQYGQGILSQDAWESLFSRVSLRLVGLKKSFYGSTLFLCRRPTPQDSPIFLPVDDTSFRWVESLKGILADEDSSRPVWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGDLVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVSTLTRGDLSSIRWVCSSLRHAQPTCPGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMAQGKHIGKVVVQVLAEEPEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGIRTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDGLLENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSAMERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTIVSGTLPQRMASCLEVLDLFLNQPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSVEVRQTLERELNLVLSVREVRQLTLRKLQELSSKADEASELACPTPKEDGLAQQQTQLNLRSLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLDSIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGSPTYVLAYTQSYRAKLTPGCEAEAETEAICFFVQQFTDMEHNRVLEALLPLKGLEERVAAAVDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIISIIHSSLAEPRVSVREG
|
Homo sapiens
|
Cytoplasm, Melanosome
|
Tissue enhanced (adipose tissue, breast)
|
{'Ciliated cells': '28.0', 'Basal respiratory cells': '32.1', 'Club cells': '50.8', 'Ionocytes': '41.2', 'Mucus glandular cells': '14.2', 'Serous glandular cells': '26.8', 'Gastric mucus-secreting cells': '32.4', 'Proximal enterocytes': '6.1', 'Paneth cells': '9.2', 'Distal enterocytes': '32.4', 'Intestinal goblet cells': '17.1', 'Exocrine glandular cells': '-0.566', 'Basal prostatic cells': '38.8', 'Prostatic glandular cells': '52.7', 'Breast glandular cells': '-0.135', 'Breast myoepithelial cells': '-0.446', 'Glandular and luminal cells': '14.2', 'Secretory cells': '9.1', 'Basal keratinocytes': '36.1', 'Suprabasal keratinocytes': '74.8', 'Basal squamous epithelial cells': '14.4', 'Squamous epithelial cells': '36.1', 'Alveolar cells type 1': '-0.056', 'Alveolar cells type 2': '0.788', 'Salivary duct cells': '10.6', 'Ductal cells': '0.532', 'Hepatocytes': '0.508', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.178', 'Distal tubular cells': '6.1', 'Collecting duct cells': '11.7', 'Mesothelial cells': '-0.246', 'Sertoli cells': '0.425', 'Granulosa cells': '9.1', 'Enteroendocrine cells': '23.1', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.498', 'Excitatory neurons': '11.5', 'Inhibitory neurons': '12.0', 'Cone photoreceptor cells': '6.8', 'Rod photoreceptor cells': '8.7', 'Bipolar cells': '33.9', 'Horizontal cells': '79.9', 'Astrocytes': '26.9', 'Oligodendrocyte precursor cells': '10.8', 'Oligodendrocytes': '16.4', 'Microglial cells': '4.5', 'Muller glia cells': '11.5', 'Schwann cells': '-0.094', 'Spermatogonia': '0.478', 'Spermatocytes': '0.202', 'Early spermatids': '-0.419', 'Late spermatids': '-0.490', 'Oocytes': '2.2', 'Cytotrophoblasts': '33.7', 'Syncytiotrophoblasts': '27.6', 'Extravillous trophoblasts': '78.9', 'Endothelial cells': '17.4', 'Lymphatic endothelial cells': '12.9', 'Cardiomyocytes': '0.397', 'Skeletal myocytes': '-0.159', 'Smooth muscle cells': '14.8', 'Adipocytes': '8.5', 'Melanocytes': '-0.101', 'Fibroblasts': '19.0', 'Peritubular cells': '0.355', 'Endometrial stromal cells': '18.7', 'Ovarian stromal cells': '4.5', 'Undifferentiated cells': '26.1', 'T-cells': '12.4', 'B-cells': '5.9', 'Plasma cells': '15.4', 'Nk-cells': '9.3', 'Granulocytes': '10.3', 'Monocytes': '5.0', 'Macrophages': '8.8', 'Hofbauer cells': '9.2', 'Kupffer cells': '42.3', 'Dendritic cells': '11.5', 'Langerhans cells': '-0.045', 'Erythroid cells': '0.077', 'Adipocytes (Subcutaneous)': '0.727', 'Adipocytes (Visceral)': '0.774', 'Breast glandular cells (progenitors)': '-0.200', 'Adipocytes (Breast)': '0.608', 'Colon enterocytes': '0.091', 'Colon enteroendocrine cells': '0.065', 'Enteric glia cells': '-0.407', 'Mitotic cells (Colon)': '0.098', 'Mitotic cells (Heart)': '0.447', 'Podocytes': '-0.236', 'Ascending Loop of Henle cells': '0.360', 'Intercalated cells': '-0.260', 'Cholangiocyte': '-0.102', 'NK-cells (Liver)': '0.099', 'Respiratory ciliated cells': '-0.151', 'Mitotic cells (Lung)': '0.197', 'NK-cells (Lung)': '-0.512', 'B-cells (Lung)': '-0.334', 'Alpha cells': '0.282', 'Beta cells': '0.256', 'Prostate glandular cells': '0.736', 'Prostate basal glandular cells': '0.310', 'Urothelial cells': '-0.016', 'Keratinocyte (other)': '-0.323', 'Keratinocyte (granular)': '0.111', 'Hair cortex cells': '0.112', 'Inner root sheath cells': '0.101', 'Outer root sheath cells': '0.136', 'Sebaceous gland cells': '0.778', 'Eccrine sweat gland cells': '0.081', 'Adipocytes (Skin)': '0.304', 'Mitotic cells (Skin)': '0.000', 'Parietal cells': '0.333', 'Chief cells': '0.443', 'Gastric mucous cells': '0.395', 'Gastric enteroendocrine cells': '0.344', 'Mitotic cells (Stomach)': '0.278', 'Parafollicular cells': '-0.040', 'Thyroid glandular cells': '0.567', 'Mitotic cells (Thyroid)': '-0.102', 'Adrenal cortex cells': '0.502', 'Adrenal medulla cells': '0.046', 'Mitotic cells (Adrenal gland)': '0.226', 'Minor salivary glandular cells': '0.023', 'Minor salivary gland ductal cells': '-0.108', 'Minor salivary gland basal cells': '0.248', 'Mitotic cells (Minor salivary gland)': '0.198', 'Adipocytes (Minor salivary gland)': '0.213', 'Somatotropes': '0.007', 'Lactotropes': '-0.007', 'Gonadotropes': '-0.197', 'Corticotropes': '0.728', 'Thyrotropes': '0.170', 'Undifferentiated cells (Pituitary gland)': '-0.238', 'Mitotic cells (Spleen)': '0.141', 'Platelets': '-0.085', 'Erythrocytes': '-0.059', 'Hematopoietic stem cells': '-0.195', 'B-cells (Spleen)': '0.351', 'NK-cells (Spleen)': '0.062', 'Amygdala excitatory': '19.4', 'Cerebellar inhibitory': '93.4', 'Cge interneuron': '27.0', 'Deep-layer corticothalamic and 6b': '17.8', 'Deep-layer intratelencephalic': '23.4', 'Deep-layer near-projecting': '25.9', 'Eccentric medium spiny neuron': '18.5', 'Hippocampal ca1-3': '17.3', 'Hippocampal ca4': '21.2', 'Hippocampal dentate gyrus': '14.2', 'Lamp5-lhx6 and chandelier': '23.5', 'Lower rhombic lip': '32.4', 'Mammillary body': '10.0', 'Medium spiny neuron': '16.0', 'Mge interneuron': '18.7', 'Midbrain-derived inhibitory': '52.4', 'Miscellaneous': '22.0', 'Splatter': '23.3', 'Thalamic excitatory': '29.0', 'Upper rhombic lip': '25.9', 'Upper-layer intratelencephalic': '17.0', 'Astrocyte': '36.2', 'Bergmann glia': '17.8', 'Central nervous system macrophage': '6.9', 'Choroid plexus epithelial cell': '12.1', 'Committed oligodendrocyte precursor': '34.7', 'Ependymal cell': '18.8', 'Oligodendrocyte': '32.1', 'Oligodendrocyte precursor cell': '21.7', 'Endothelial cell': '5.5', 'Pericyte': '9.9', 'Vascular associated smooth muscle cell': '15.4', 'Fibroblast': '15.2', 'Leukocyte': '10.9', 'Basophil': '0.1', 'Eosinophil': '0.0', 'Neutrophil': '0.2', 'Classical monocyte': '5.3', 'Non-classical monocyte': '4.1', 'Intermediate monocyte': '3.5', 'T-reg': '6.3', 'GdT-cell': '0.1', 'MAIT T-cell': '3.7', 'Memory CD4 T-cell': '0.2', 'Naive CD4 T-cell': '11.3', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '19.7', 'Memory B-cell': '0.0', 'Naive B-cell': '3.7', 'Plasmacytoid DC': '3.9', 'Myeloid DC': '3.5', 'NK-cell': '13.6', 'Total PBMC': '2.2', 'Vd2 gdTCR': '4.5', 'Memory CD4 T-cell Th1\\/Th17': '14.9', 'Memory CD4 T-cell Th17': '27.5', 'Memory CD4 T-cell Th2': '35.8', 'Non-Vd2 gdTCR': '11.0', 'Memory CD4 T-cell Th1': '36.0', 'Memory CD4 T-cell TFH': '69.9', 'Terminal effector memory CD4 T-cell': '4.6', 'Central memory CD8 T-cell': '4.1', 'Effector memory CD8 T-cell': '3.4', 'Terminal effector memory CD8 T-cell': '3.3', 'Non-switched memory B-cell': '2.5', 'Plasmablast': '5.0', 'Switched memory B-cell': '1.5', 'Exhausted memory B-cell': '1.8', 'Progenitor cell': '5.7', 'Memory T-reg': '36.3', 'Naive CD4 T-cell activated': '77.4', 'Naive CD8 T-cell activated': '86.4', 'Naive T-reg': '20.6'}
|
1XKT, 2CG5, 2JFD, 2JFK, 2PX6, 3HHD, 3TJM, 4PIV, 4W82, 4W9N, 4Z49, 5C37, 6NNA, 7MHD, 7MHE, 8EYI, 8EYK, 8G7X, 8GKC
|
{'Adipose Tissue': 643.0579235880399, 'Adrenal Gland': 50.82914728682171, 'Bladder': 61.9547619047619, 'Blood': 20.211749407965552, 'Blood Vessel': 63.16825617977528, 'Brain': 60.582436790310375, 'Breast': 523.2381481481482, 'Cervix Uteri': 49.59578947368421, 'Colon': 38.83715532734275, 'Esophagus': 66.04310865051903, 'Fallopian Tube': 39.621111111111105, 'Heart': 15.84287781649245, 'Kidney': 16.600123595505618, 'Liver': 146.771296460177, 'Lung': 128.46955017301036, 'Muscle': 27.402997509339976, 'Nerve': 110.618901453958, 'Ovary': 39.32761111111111, 'Pancreas': 15.425536585365856, 'Pituitary': 158.83374558303885, 'Prostate': 157.39608163265308, 'Salivary Gland': 65.55281481481482, 'Skin': 131.1030458817026, 'Small Intestine': 54.713422459893046, 'Spleen': 18.278008298755186, 'Stomach': 92.0099860724234, 'Testis': 33.143326869806096, 'Thyroid': 53.63954058192956, 'Uterus': 40.136267605633805, 'Vagina': 69.89929487179488}
|
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0.09, 0.02, 0.02, 0.13, 0.0, 0.0, 0.1, 0.06, 0.01, 0.13, 0.63, 0.12, 0.31, 0.0, 0.41, 0.19, 0.0, 0.0, 0.0, 0.05, 0.21, 0.8, 0.61, 0.15, 0.37, 0.73, 0.37, 0.01, 0.05, 0.12, 0.17, 0.13, 0.01, 0.01, 0.36, 0.24, 0.0, 0.52, 0.65, 0.53, 0.6, 0.06, 0.5, 0.09, 0.3, 0.33, 0.03, 0.64, 0.25, 0.54, 0.05, 0.27, 0.5, 0.27, 0.81, 0.15, 0.0, 0.41, 0.31, 0.0, 0.04, 0.48, 0.22, 0.0, 0.52, 0.8, 0.23, 0.12, 0.4, 0.05, 0.0, 0.0, 0.04, 0.0, 0.03, 0.14, 0.16, 0.39, 0.2, 0.38, 0.42, 0.42, 0.11, 0.07, 0.05, 0.55, 0.44, 0.0, 0.31, 0.14, 0.65, 0.34, 0.0, 0.47, 0.31, 0.0, 0.02, 0.37, 0.15, 0.04, 0.14, 0.32, 0.0, 0.0, 0.44, 0.15, 0.01, 0.11, 0.53, 0.03, 0.03, 0.41, 0.54, 0.66, 0.11, 0.92, 0.43, 0.11, 0.44, 0.12, 0.03, 0.02, 0.01, 0.07, 0.04, 0.14, 0.12, 0.14, 0.02, 0.14, 0.1, 0.07, 0.1, 0.07, 0.04, 0.09, 0.0, 0.0, 0.13, 0.0, 0.06, 0.0, 0.0, 0.0, 0.0, 0.01, 0.0, 0.03, 0.03, 0.0, 0.01, 0.46, 0.02, 0.38, 0.52, 0.5, 0.78, 0.34, 0.18, 0.09, 0.07, 0.01, 0.0, 0.01, 0.02, 0.26, 0.09, 0.2, 0.0, 0.05, 0.03, 0.11, 0.53, 0.27, 0.08, 0.66, 0.75, 0.37, 0.68, 0.41, 0.18, 0.68, 0.25, 0.42, 0.15, 0.21, 0.21, 0.06, 0.19, 0.09, 0.01, 0.17, 0.01, 0.42, 0.13, 0.0, 0.12, 0.51, 0.07, 0.0, 0.13, 0.25, 0.01, 0.14, 0.23, 0.18, 0.69, 0.28, 0.26, 0.0, 0.0, 0.01, 0.0, 0.01, 0.07, 0.26, 0.07, 0.82, 0.41, 0.58, 0.8, 0.8, 0.83, 1.0, 0.78, 0.92, 0.95, 0.77, 0.69, 0.82, 0.31, 0.04, 0.01, 0.56, 0.3, 0.0, 0.02, 0.61, 0.19, 0.12, 0.68, 0.2, 0.8, 0.59, 0.25, 0.83, 0.8, 0.22, 0.32, 0.25, 0.42, 0.24, 0.2, 0.0, 0.33, 0.65, 0.24, 0.55, 0.04, 0.44, 0.35, 0.26, 0.11, 0.0, 0.05, 0.13, 0.0, 0.14, 0.31, 0.07, 0.0, 0.27, 0.59, 0.67, 0.24, 0.61, 0.32, 0.79, 0.21, 0.43, 0.11, 0.52, 0.48, 0.0, 0.21, 0.59, 0.08, 0.17, 0.0, 0.41, 0.53, 0.0, 0.38, 0.47, 0.25, 0.19, 0.63, 0.69, 0.38, 0.66, 0.83, 0.66, 0.89, 0.94, 0.9, 0.96, 0.95, 0.97, 0.94, 0.97, 0.92, 1.0, 0.92, 0.99, 0.96, 0.97, 0.99, 0.89, 0.98, 0.93, 0.92, 0.65, 0.65, 0.14, 0.64, 0.33, 0.21, 0.11, 0.04, 0.52, 0.08, 0.74, 0.25, 0.57, 0.1, 0.23, 0.31, 0.51, 0.11, 0.08, 0.88, 0.25, 0.9, 0.4, 0.99, 0.48, 0.49, 0.11, 0.02, 0.0, 0.0, 0.0, 0.0, 0.05, 0.19, 0.23, 0.01, 0.06, 0.0, 0.36, 0.36, 0.0, 0.43, 0.4, 0.0, 0.0, 0.7, 0.57, 0.02, 0.55, 0.05, 0.06, 0.0, 0.18, 0.0, 0.0, 0.07, 0.01, 0.03, 0.48, 0.56, 0.1, 0.29, 0.18, 0.64, 0.34, 0.01, 0.28, 0.29, 0.01, 0.0, 0.37, 0.28, 0.0, 0.02, 0.53, 0.07, 0.0, 0.35, 0.77, 0.38, 0.14, 0.7, 0.84, 0.54, 0.18, 0.04, 0.15, 0.0, 0.0, 0.0, 0.07, 0.17, 0.02, 0.0, 0.0, 0.01, 0.0, 0.0, 0.0, 0.07, 0.0, 0.0, 0.12, 0.18, 0.04, 0.23, 0.78, 0.55, 0.33, 0.83, 0.96, 0.68, 0.71, 0.43, 0.55, 0.03, 0.36, 0.02, 0.06, 0.0, 0.0, 0.01, 0.0, 0.01, 0.08, 0.29, 0.05, 0.11, 0.25, 0.21, 0.25, 0.11, 0.54, 0.16, 0.35, 0.6, 0.76, 0.71, 0.2, 0.61, 0.94, 0.94, 0.36, 0.54, 0.38, 0.28, 0.33, 0.16, 0.0, 0.24, 0.11, 0.0, 0.0, 0.37, 0.04, 0.0, 0.34, 0.19, 0.06, 0.06, 0.68, 0.31, 0.28, 0.3, 0.54, 0.41, 0.0, 0.24, 0.72, 0.42, 0.0, 0.46, 0.76, 0.28, 0.85, 0.29, 0.11, 0.57, 0.48, 0.02, 0.01, 0.45, 0.23, 0.0, 0.04, 0.42, 0.17, 0.0, 0.23, 0.78, 0.63, 0.33, 0.89, 0.57, 0.15, 0.47, 0.5, 0.63, 0.27, 0.0, 0.3, 0.1, 0.05, 0.0, 0.36, 0.05, 0.04, 0.11, 0.39, 0.01, 0.14, 0.41, 0.06, 0.05, 0.33, 0.63, 0.04, 0.75, 0.23, 0.82, 0.61, 0.52, 0.01, 0.49, 0.01, 0.56, 0.01, 0.18, 0.0, 0.0, 0.18, 0.0, 0.57, 0.5, 0.4, 0.35, 0.35, 0.45, 0.03, 0.68, 0.87, 0.13, 0.43, 0.56, 0.21, 0.01, 0.2, 0.0, 0.55, 0.65, 0.2, 0.05, 0.57, 0.24, 0.7, 0.27, 0.25, 0.38, 0.34, 0.65, 0.02, 0.49, 0.26, 0.41, 0.29, 0.67, 0.38, 0.0, 0.04, 0.62, 0.69, 0.6, 0.01, 0.06, 0.47, 0.39, 0.0, 0.09, 0.59, 0.15, 0.01, 0.35, 0.62, 0.43, 0.2, 0.65, 0.88, 0.87, 0.93, 0.85, 0.92, 0.9, 0.96, 1.0, 0.99]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 85.71039
| 0.277025
| 56
|
O43791
|
P52945
|
nan, UNIPROT
|
degron_data, 31181401
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
PDX1
|
MNGEEQYYAATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQGSPPDISPYEVPPLADDPAVAHLHHHLPAQLALPHPPAGPFPEGAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPPPPPPGGAVPPAAPVAAREGRLPPGLSASPQPSSVAPRRPQEPR
|
Homo sapiens
|
Nucleus, Cytoplasm, cytosol
|
Group enriched (intestine, pancreas)
|
{'Ciliated cells': '0.0', 'Basal respiratory cells': '0.0', 'Club cells': '0.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.0', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '4.7', 'Proximal enterocytes': '0.2', 'Paneth cells': '0.1', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.8', 'Exocrine glandular cells': '-0.492', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.052', 'Breast myoepithelial cells': '-0.011', 'Glandular and luminal cells': '0.0', 'Secretory cells': '0.0', 'Basal keratinocytes': '0.0', 'Suprabasal keratinocytes': '0.0', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '-0.006', 'Alveolar cells type 2': '0.003', 'Salivary duct cells': '0.0', 'Ductal cells': '0.506', 'Hepatocytes': '-0.025', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '-0.166', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.017', 'Sertoli cells': '0.203', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '7.4', 'Pancreatic endocrine cells': '20.4', 'Leydig cells': '0.128', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.002', 'Spermatogonia': '0.279', 'Spermatocytes': '0.099', 'Early spermatids': '-0.118', 'Late spermatids': '-0.065', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '0.0', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.034', 'Skeletal myocytes': '0.043', 'Smooth muscle cells': '0.0', 'Adipocytes': '0.0', 'Melanocytes': '-0.018', 'Fibroblasts': '0.0', 'Peritubular cells': '0.073', 'Endometrial stromal cells': '0.0', 'Ovarian stromal cells': '0.0', 'Undifferentiated cells': '0.2', 'T-cells': '0.0', 'B-cells': '0.0', 'Plasma cells': '0.0', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.0', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '-0.016', 'Erythroid cells': '0.008', 'Adipocytes (Subcutaneous)': '0.063', 'Adipocytes (Visceral)': '0.037', 'Breast glandular cells (progenitors)': '0.119', 'Adipocytes (Breast)': '-0.059', 'Colon enterocytes': '0.513', 'Colon enteroendocrine cells': '-0.062', 'Enteric glia cells': '-0.194', 'Mitotic cells (Colon)': '0.340', 'Mitotic cells (Heart)': '0.029', 'Podocytes': '-0.090', 'Ascending Loop of Henle cells': '0.057', 'Intercalated cells': '-0.119', 'Cholangiocyte': '0.444', 'NK-cells (Liver)': '-0.073', 'Respiratory ciliated cells': '0.013', 'Mitotic cells (Lung)': '0.039', 'NK-cells (Lung)': '-0.019', 'B-cells (Lung)': '-0.026', 'Alpha cells': '0.458', 'Beta cells': '0.422', 'Prostate glandular cells': '0.001', 'Prostate basal glandular cells': '0.042', 'Urothelial cells': '-0.077', 'Keratinocyte (other)': '0.034', 'Keratinocyte (granular)': '-0.134', 'Hair cortex cells': '0.051', 'Inner root sheath cells': '0.050', 'Outer root sheath cells': '0.075', 'Sebaceous gland cells': '0.003', 'Eccrine sweat gland cells': '0.131', 'Adipocytes (Skin)': '0.000', 'Mitotic cells (Skin)': '0.051', 'Parietal cells': '0.523', 'Chief cells': '0.380', 'Gastric mucous cells': '0.591', 'Gastric enteroendocrine cells': '0.558', 'Mitotic cells (Stomach)': '0.239', 'Parafollicular cells': '0.091', 'Thyroid glandular cells': '0.052', 'Mitotic cells (Thyroid)': '0.029', 'Adrenal cortex cells': '0.109', 'Adrenal medulla cells': '0.036', 'Mitotic cells (Adrenal gland)': '-0.034', 'Minor salivary glandular cells': '0.099', 'Minor salivary gland ductal cells': '0.155', 'Minor salivary gland basal cells': '0.013', 'Mitotic cells (Minor salivary gland)': '-0.144', 'Adipocytes (Minor salivary gland)': '-0.022', 'Somatotropes': '-0.060', 'Lactotropes': '-0.077', 'Gonadotropes': '0.011', 'Corticotropes': '-0.038', 'Thyrotropes': '-0.032', 'Undifferentiated cells (Pituitary gland)': '0.001', 'Mitotic cells (Spleen)': '0.001', 'Platelets': '0.082', 'Erythrocytes': '0.063', 'Hematopoietic stem cells': '0.022', 'B-cells (Spleen)': '-0.040', 'NK-cells (Spleen)': '-0.039', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.0', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.0', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '0.0', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.0', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.0', 'Oligodendrocyte': '0.0', 'Oligodendrocyte precursor cell': '0.0', 'Endothelial cell': '0.0', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.0', 'Leukocyte': '0.0', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
|
6F8F, 7KPK
|
{'Adipose Tissue': 0.0105765714285714, 'Adrenal Gland': 0.010078965116279, 'Bladder': 0.0070080952380952, 'Blood': 0.2420001345532831, 'Blood Vessel': 0.0087559483146067, 'Brain': 0.0045948099924299, 'Breast': 0.0051267233115468, 'Cervix Uteri': 0.0067121052631578, 'Colon': 0.1671811386392811, 'Esophagus': 0.0114100830449826, 'Fallopian Tube': 0.0056444444444444, 'Heart': 0.0022885423925667, 'Kidney': 0.0047994719101123, 'Liver': 0.2879592035398229, 'Lung': 0.0049712041522491, 'Muscle': 0.0023987858032378, 'Nerve': 0.0123379757673667, 'Ovary': 0.0064736666666666, 'Pancreas': 9.837112804878048, 'Pituitary': 0.0068373356890459, 'Prostate': 0.0052368122448979, 'Salivary Gland': 0.0041129012345679, 'Skin': 0.0049417003869541, 'Small Intestine': 0.2546254545454545, 'Spleen': 0.0055046680497925, 'Stomach': 0.7270136768802228, 'Testis': 0.1983810803324099, 'Thyroid': 0.0057743583460949, 'Uterus': 0.0049721126760563, 'Vagina': 0.0041943589743589}
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[43.03, 48.68, 49.22, 53.62, 51.45, 51.59, 54.32, 46.68, 51.21, 49.41, 51.36, 47.77, 55.46, 45.76, 53.17, 49.6, 56.58, 44.95, 50.12, 50.06, 49.18, 51.98, 58.45, 56.33, 50.21, 58.99, 50.61, 54.99, 60.78, 60.2, 62.97, 64.62, 60.85, 58.39, 58.09, 51.96, 48.57, 51.38, 44.17, 52.05, 49.02, 63.27, 69.74, 76.3, 77.24, 75.0, 72.98, 67.45, 71.54, 61.88, 50.69, 49.44, 46.86, 52.72, 43.73, 46.22, 50.0, 53.12, 49.35, 47.98, 47.7, 61.3, 56.38, 47.03, 51.6, 52.02, 51.44, 49.15, 56.37, 62.83, 69.28, 62.22, 45.75, 58.83, 53.67, 49.81, 54.43, 48.86, 50.88, 47.63, 49.49, 45.98, 50.71, 48.62, 53.85, 51.3, 46.39, 54.3, 43.76, 50.27, 47.71, 54.78, 54.51, 55.9, 69.04, 59.29, 50.04, 54.88, 57.15, 54.92, 50.55, 45.76, 47.44, 47.89, 51.09, 56.41, 44.87, 48.35, 49.76, 46.66, 48.12, 51.84, 50.68, 62.74, 65.83, 72.57, 81.52, 85.48, 87.92, 83.69, 86.58, 85.59, 76.67, 68.23, 63.03, 59.02, 57.52, 54.09, 55.76, 55.32, 58.41, 57.47, 55.85, 53.73, 59.3, 50.28, 45.01, 43.21, 44.78, 49.36, 48.58, 60.34, 56.2, 58.15, 59.05, 58.87, 61.41, 73.93, 82.78, 88.26, 89.4, 95.28, 97.85, 98.34, 98.34, 98.18, 98.54, 98.49, 98.51, 98.58, 98.75, 98.68, 98.48, 98.54, 98.71, 97.84, 98.13, 97.85, 98.01, 98.63, 98.4, 98.44, 98.53, 98.37, 98.54, 98.71, 98.73, 98.65, 98.56, 98.6, 98.5, 98.2, 98.13, 98.12, 97.6, 98.12, 98.53, 97.94, 97.78, 98.54, 98.32, 98.23, 98.56, 98.77, 98.61, 98.38, 98.64, 98.54, 98.19, 97.49, 97.16, 96.43, 95.06, 94.63, 91.31, 88.84, 88.57, 87.88, 78.55, 64.73, 56.57, 50.84, 47.15, 53.22, 52.92, 44.19, 40.3, 35.99, 34.19, 48.59, 45.43, 50.58, 50.8, 46.29, 41.16, 40.6, 45.83, 48.53, 42.26, 43.82, 41.87, 45.36, 40.12, 45.32, 47.9, 47.21, 44.14, 56.43, 70.25, 66.74, 67.97, 67.23, 72.4, 49.89, 45.8, 46.1, 50.15, 55.42, 56.29, 58.87, 48.26, 55.51, 58.8, 57.73, 50.8, 52.39, 53.91, 52.63, 49.91, 54.55, 54.97, 68.46, 56.79, 44.36, 58.72, 62.63, 61.54, 61.78, 72.46, 68.0, 71.29, 67.72, 59.93, 68.77, 72.03, 74.03, 71.62, 74.4, 74.98, 68.95, 69.18, 76.43, 62.9]
|
[0.99, 1.0, 0.96, 1.0, 0.99, 1.0, 0.99, 0.93, 0.89, 0.84, 0.88, 0.96, 0.94, 0.95, 0.9, 0.9, 0.77, 0.82, 0.8, 0.83, 0.93, 0.93, 0.72, 0.93, 0.81, 0.88, 0.93, 0.86, 0.72, 0.82, 0.76, 0.9, 0.91, 0.71, 0.88, 0.71, 0.9, 0.73, 0.8, 0.91, 0.92, 0.92, 0.95, 0.94, 0.93, 0.87, 0.94, 0.85, 0.92, 0.94, 0.96, 0.96, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.96, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.88, 0.97, 0.72, 0.94, 0.99, 0.98, 0.99, 0.99, 1.0, 1.0, 1.0, 0.98, 1.0, 0.97, 1.0, 0.92, 1.0, 0.94, 0.99, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 0.97, 0.99, 0.96, 0.98, 0.96, 0.97, 0.95, 1.0, 0.99, 1.0, 0.97, 0.92, 0.98, 0.93, 0.78, 0.91, 0.88, 0.82, 0.7, 0.86, 0.81, 0.8, 0.65, 0.89, 0.21, 0.84, 0.56, 0.68, 0.78, 0.29, 0.64, 0.78, 0.29, 0.64, 0.4, 0.43, 0.51, 0.66, 0.76, 0.51, 0.76, 0.82, 0.68, 0.81, 0.63, 0.93, 0.95, 0.85, 0.96, 0.81, 0.67, 0.58, 0.85, 0.74, 0.51, 0.76, 0.82, 0.96, 0.58, 0.92, 0.27, 0.54, 0.74, 0.6, 0.15, 0.43, 0.54, 0.3, 0.0, 0.29, 0.57, 0.12, 0.01, 0.68, 0.83, 0.53, 0.27, 0.64, 0.2, 0.61, 0.77, 0.63, 0.3, 0.24, 0.44, 0.45, 0.0, 0.1, 0.73, 0.58, 0.11, 0.83, 0.16, 0.55, 0.39, 0.54, 0.29, 0.0, 0.61, 0.32, 0.13, 0.04, 0.55, 0.55, 0.18, 0.31, 0.53, 0.62, 0.35, 0.57, 0.69, 0.45, 0.28, 0.56, 0.83, 0.78, 0.82, 0.55, 0.84, 0.76, 0.97, 0.99, 0.99, 0.96, 0.99, 1.0, 0.97, 0.91, 0.92, 0.83, 0.65, 0.98, 0.78, 0.88, 0.93, 0.75, 0.83, 0.86, 0.75, 0.67, 0.91, 0.87, 0.86, 0.98, 0.72, 0.96, 0.94, 0.94, 0.91, 0.95, 0.94, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.96, 0.9, 1.0, 0.94, 0.99, 0.94, 0.96, 0.92, 0.94, 0.95, 0.88, 0.93, 0.89, 0.87, 0.96, 0.95, 0.96, 0.95, 0.96, 0.98, 0.97, 0.98]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 64.521272
| 0.793852
| 2,449
|
O43791
|
P60484
|
nan, 24656772, UNIPROT
|
degron_data, UbiNet, UbiBrowser, 31181401
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
PTEN
|
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
|
Homo sapiens
|
Cytoplasm, Nucleus, Nucleus, PML body, Cell projection, dendritic spine, Postsynaptic density, Secreted
|
Low tissue specificity
|
{'Ciliated cells': '34.7', 'Basal respiratory cells': '24.4', 'Club cells': '41.2', 'Ionocytes': '19.5', 'Mucus glandular cells': '31.9', 'Serous glandular cells': '53.3', 'Gastric mucus-secreting cells': '39.5', 'Proximal enterocytes': '40.3', 'Paneth cells': '37.7', 'Distal enterocytes': '54.6', 'Intestinal goblet cells': '46.7', 'Exocrine glandular cells': '-0.548', 'Basal prostatic cells': '44.4', 'Prostatic glandular cells': '36.1', 'Breast glandular cells': '-0.229', 'Breast myoepithelial cells': '-0.337', 'Glandular and luminal cells': '27.5', 'Secretory cells': '50.5', 'Basal keratinocytes': '45.9', 'Suprabasal keratinocytes': '50.4', 'Basal squamous epithelial cells': '45.7', 'Squamous epithelial cells': '42.3', 'Alveolar cells type 1': '0.015', 'Alveolar cells type 2': '-0.333', 'Salivary duct cells': '32.9', 'Ductal cells': '0.522', 'Hepatocytes': '0.237', 'Cholangiocytes': '45.8', 'Proximal tubular cells': '0.169', 'Distal tubular cells': '15.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '-0.026', 'Sertoli cells': '-0.192', 'Granulosa cells': '22.8', 'Enteroendocrine cells': '28.0', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '-0.043', 'Excitatory neurons': '136.2', 'Inhibitory neurons': '126.7', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '54.9', 'Bipolar cells': '84.0', 'Horizontal cells': '47.8', 'Astrocytes': '79.3', 'Oligodendrocyte precursor cells': '130.6', 'Oligodendrocytes': '89.1', 'Microglial cells': '187.9', 'Muller glia cells': '55.2', 'Schwann cells': '0.259', 'Spermatogonia': '0.079', 'Spermatocytes': '0.281', 'Early spermatids': '0.555', 'Late spermatids': '0.136', 'Oocytes': '18.4', 'Cytotrophoblasts': '17.7', 'Syncytiotrophoblasts': '34.4', 'Extravillous trophoblasts': '35.3', 'Endothelial cells': '40.5', 'Lymphatic endothelial cells': '33.6', 'Cardiomyocytes': '0.544', 'Skeletal myocytes': '-0.216', 'Smooth muscle cells': '135.5', 'Adipocytes': '52.5', 'Melanocytes': '0.017', 'Fibroblasts': '90.5', 'Peritubular cells': '0.110', 'Endometrial stromal cells': '95.1', 'Ovarian stromal cells': '33.0', 'Undifferentiated cells': '38.2', 'T-cells': '42.8', 'B-cells': '52.5', 'Plasma cells': '34.4', 'Nk-cells': '44.4', 'Granulocytes': '40.8', 'Monocytes': '216.4', 'Macrophages': '97.1', 'Hofbauer cells': '35.4', 'Kupffer cells': '160.0', 'Dendritic cells': '62.0', 'Langerhans cells': '0.062', 'Erythroid cells': '0.155', 'Adipocytes (Subcutaneous)': '0.348', 'Adipocytes (Visceral)': '0.287', 'Breast glandular cells (progenitors)': '-0.197', 'Adipocytes (Breast)': '0.582', 'Colon enterocytes': '-0.162', 'Colon enteroendocrine cells': '0.365', 'Enteric glia cells': '0.405', 'Mitotic cells (Colon)': '-0.024', 'Mitotic cells (Heart)': '0.534', 'Podocytes': '0.017', 'Ascending Loop of Henle cells': '0.411', 'Intercalated cells': '-0.005', 'Cholangiocyte': '0.283', 'NK-cells (Liver)': '-0.021', 'Respiratory ciliated cells': '-0.001', 'Mitotic cells (Lung)': '-0.068', 'NK-cells (Lung)': '0.106', 'B-cells (Lung)': '0.077', 'Alpha cells': '0.447', 'Beta cells': '0.268', 'Prostate glandular cells': '-0.492', 'Prostate basal glandular cells': '-0.150', 'Urothelial cells': '0.050', 'Keratinocyte (other)': '-0.123', 'Keratinocyte (granular)': '-0.213', 'Hair cortex cells': '0.026', 'Inner root sheath cells': '0.141', 'Outer root sheath cells': '0.232', 'Sebaceous gland cells': '0.175', 'Eccrine sweat gland cells': '0.150', 'Adipocytes (Skin)': '0.226', 'Mitotic cells (Skin)': '0.233', 'Parietal cells': '-0.626', 'Chief cells': '-0.457', 'Gastric mucous cells': '-0.513', 'Gastric enteroendocrine cells': '-0.328', 'Mitotic cells (Stomach)': '-0.071', 'Parafollicular cells': '0.026', 'Thyroid glandular cells': '0.255', 'Mitotic cells (Thyroid)': '0.080', 'Adrenal cortex cells': '0.466', 'Adrenal medulla cells': '0.137', 'Mitotic cells (Adrenal gland)': '0.369', 'Minor salivary glandular cells': '0.369', 'Minor salivary gland ductal cells': '0.083', 'Minor salivary gland basal cells': '0.484', 'Mitotic cells (Minor salivary gland)': '0.482', 'Adipocytes (Minor salivary gland)': '0.435', 'Somatotropes': '-0.164', 'Lactotropes': '-0.103', 'Gonadotropes': '-0.079', 'Corticotropes': '-0.068', 'Thyrotropes': '0.126', 'Undifferentiated cells (Pituitary gland)': '0.285', 'Mitotic cells (Spleen)': '-0.350', 'Platelets': '0.006', 'Erythrocytes': '-0.209', 'Hematopoietic stem cells': '-0.101', 'B-cells (Spleen)': '0.186', 'NK-cells (Spleen)': '0.234', 'Amygdala excitatory': '205.9', 'Cerebellar inhibitory': '243.7', 'Cge interneuron': '187.7', 'Deep-layer corticothalamic and 6b': '208.3', 'Deep-layer intratelencephalic': '187.6', 'Deep-layer near-projecting': '204.7', 'Eccentric medium spiny neuron': '242.6', 'Hippocampal ca1-3': '187.3', 'Hippocampal ca4': '167.1', 'Hippocampal dentate gyrus': '185.4', 'Lamp5-lhx6 and chandelier': '218.8', 'Lower rhombic lip': '174.1', 'Mammillary body': '217.2', 'Medium spiny neuron': '189.9', 'Mge interneuron': '159.6', 'Midbrain-derived inhibitory': '240.2', 'Miscellaneous': '218.2', 'Splatter': '179.9', 'Thalamic excitatory': '190.1', 'Upper rhombic lip': '450.6', 'Upper-layer intratelencephalic': '178.1', 'Astrocyte': '147.6', 'Bergmann glia': '136.2', 'Central nervous system macrophage': '354.6', 'Choroid plexus epithelial cell': '276.7', 'Committed oligodendrocyte precursor': '127.5', 'Ependymal cell': '225.9', 'Oligodendrocyte': '128.3', 'Oligodendrocyte precursor cell': '186.5', 'Endothelial cell': '373.6', 'Pericyte': '1886.3', 'Vascular associated smooth muscle cell': '554.1', 'Fibroblast': '430.3', 'Leukocyte': '255.0', 'Basophil': '134.4', 'Eosinophil': '27.7', 'Neutrophil': '620.5', 'Classical monocyte': '43.7', 'Non-classical monocyte': '46.9', 'Intermediate monocyte': '134.3', 'T-reg': '87.1', 'GdT-cell': '7.2', 'MAIT T-cell': '83.0', 'Memory CD4 T-cell': '7.7', 'Naive CD4 T-cell': '42.3', 'Memory CD8 T-cell': '6.8', 'Naive CD8 T-cell': '37.1', 'Memory B-cell': '8.2', 'Naive B-cell': '52.5', 'Plasmacytoid DC': '91.8', 'Myeloid DC': '153.8', 'NK-cell': '24.3', 'Total PBMC': '138.1', 'Vd2 gdTCR': '80.0', 'Memory CD4 T-cell Th1\\/Th17': '37.1', 'Memory CD4 T-cell Th17': '29.3', 'Memory CD4 T-cell Th2': '33.7', 'Non-Vd2 gdTCR': '86.1', 'Memory CD4 T-cell Th1': '26.7', 'Memory CD4 T-cell TFH': '26.3', 'Terminal effector memory CD4 T-cell': '101.8', 'Central memory CD8 T-cell': '86.1', 'Effector memory CD8 T-cell': '90.1', 'Terminal effector memory CD8 T-cell': '79.6', 'Non-switched memory B-cell': '116.3', 'Plasmablast': '63.7', 'Switched memory B-cell': '94.0', 'Exhausted memory B-cell': '96.1', 'Progenitor cell': '109.9', 'Memory T-reg': '23.9', 'Naive CD4 T-cell activated': '16.8', 'Naive CD8 T-cell activated': '13.6', 'Naive T-reg': '44.2'}
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1D5R, 2KYL, 4O1V, 5BUG, 5BZX, 5BZZ, 7JTX, 7JUK, 7JUL, 7JVX, 7PC7, 8X3S
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{'Adipose Tissue': 47.57878073089701, 'Adrenal Gland': 18.557232558139532, 'Bladder': 29.20047619047619, 'Blood': 50.926940796555435, 'Blood Vessel': 40.20957303370786, 'Brain': 16.370822104466313, 'Breast': 39.58758169934641, 'Cervix Uteri': 60.99526315789474, 'Colon': 24.48421694480103, 'Esophagus': 22.88764152249135, 'Fallopian Tube': 51.95666666666667, 'Heart': 10.49512775842044, 'Kidney': 13.56823595505618, 'Liver': 11.71562831858407, 'Lung': 33.48531141868512, 'Muscle': 10.279891656288918, 'Nerve': 48.74345718901454, 'Ovary': 34.155277777777776, 'Pancreas': 10.43135975609756, 'Pituitary': 18.875212014134277, 'Prostate': 28.91016326530612, 'Salivary Gland': 14.054104938271603, 'Skin': 22.39354284134881, 'Small Intestine': 22.586106951871656, 'Spleen': 35.62920746887966, 'Stomach': 17.857805013927578, 'Testis': 21.24296398891967, 'Thyroid': 32.27920367534456, 'Uterus': 45.98943661971831, 'Vagina': 41.38442307692308}
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|
[0.78, 0.53, 0.46, 0.64, 0.37, 0.13, 0.48, 0.64, 0.37, 0.04, 0.56, 0.37, 0.1, 0.43, 0.18, 0.12, 0.53, 0.61, 0.66, 0.87, 0.1, 0.28, 0.0, 0.09, 0.01, 0.12, 0.29, 0.06, 0.3, 0.74, 0.34, 0.04, 0.0, 0.0, 0.0, 0.05, 0.05, 0.0, 0.0, 0.4, 0.91, 0.8, 0.29, 0.07, 0.41, 0.39, 0.18, 0.03, 0.31, 0.01, 0.56, 0.23, 0.0, 0.18, 0.5, 0.0, 0.0, 0.32, 0.64, 0.53, 0.17, 0.73, 0.63, 0.27, 0.0, 0.21, 0.0, 0.0, 0.01, 0.0, 0.0, 0.34, 0.53, 0.19, 0.63, 0.12, 0.52, 0.34, 0.52, 0.34, 0.0, 0.51, 0.64, 0.21, 0.21, 0.13, 0.57, 0.14, 0.49, 0.05, 0.46, 0.33, 0.39, 0.17, 0.1, 0.02, 0.59, 0.04, 0.59, 0.21, 0.0, 0.48, 0.41, 0.0, 0.0, 0.42, 0.24, 0.0, 0.19, 0.58, 0.13, 0.1, 0.6, 0.58, 0.31, 0.95, 0.6, 0.09, 0.02, 0.0, 0.01, 0.0, 0.0, 0.03, 0.17, 0.39, 0.0, 0.31, 0.21, 0.01, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.01, 0.06, 0.01, 0.08, 0.29, 0.56, 0.56, 0.63, 0.18, 0.81, 0.48, 0.03, 0.33, 0.44, 0.0, 0.03, 0.49, 0.26, 0.0, 0.0, 0.46, 0.22, 0.0, 0.02, 0.72, 0.4, 0.62, 0.31, 0.04, 0.04, 0.45, 0.16, 0.09, 0.0, 0.02, 0.23, 0.12, 0.01, 0.0, 0.21, 0.08, 0.05, 0.13, 0.18, 0.09, 0.31, 0.53, 0.48, 0.83, 0.4, 0.79, 0.24, 0.58, 0.58, 0.21, 0.45, 0.0, 0.27, 0.0, 0.17, 0.22, 0.0, 0.1, 0.0, 0.18, 0.19, 0.15, 0.0, 0.38, 0.2, 0.49, 0.95, 0.54, 0.33, 0.13, 0.27, 0.01, 0.18, 0.03, 0.15, 0.0, 0.21, 0.3, 0.47, 0.78, 0.62, 0.68, 0.33, 0.25, 0.59, 0.09, 0.88, 0.42, 0.26, 0.34, 0.53, 0.45, 0.55, 0.41, 0.78, 0.63, 0.33, 0.01, 0.13, 0.01, 0.4, 0.07, 0.81, 0.88, 0.42, 0.1, 0.69, 0.03, 0.28, 0.06, 0.07, 0.0, 0.18, 0.0, 0.13, 0.0, 0.08, 0.05, 0.46, 0.45, 0.85, 0.99, 0.6, 0.97, 0.76, 0.44, 0.38, 0.54, 0.0, 0.01, 0.2, 0.0, 0.13, 0.0, 0.0, 0.0, 0.16, 0.09, 0.02, 0.2, 0.37, 0.37, 0.9, 0.5, 0.67, 0.74, 0.84, 0.96, 0.87, 0.97, 0.97, 1.0, 0.92, 0.9, 0.61, 0.39, 0.71, 0.58, 0.21, 0.36, 0.72, 0.28, 0.2, 0.43, 0.47, 0.3, 0.85, 0.34, 0.99, 0.83, 0.91, 0.56, 0.53, 0.12, 0.08, 0.0, 0.04, 0.19, 0.02, 0.37, 0.06, 0.63, 0.26, 0.0, 0.02, 0.49, 0.0, 0.14, 0.45, 0.11, 0.59, 0.67, 0.35, 0.78, 0.53, 0.02, 0.3, 0.64, 0.69, 0.01, 0.35, 0.0, 0.16, 0.0, 0.08, 0.0, 0.2, 0.48, 0.51, 0.71, 0.94, 0.69, 0.81, 0.95, 0.82, 0.92, 0.92, 1.0, 0.93, 1.0, 0.9, 0.9, 0.94, 0.85, 0.93, 0.86, 0.94, 0.91, 0.82, 0.96, 0.91, 0.97, 0.83, 0.72, 0.9, 0.82, 0.93, 0.73, 0.72, 0.69, 0.82, 0.77, 0.51, 0.43, 0.42, 0.73, 0.58, 0.77, 0.9, 0.83, 0.86, 0.86, 0.84, 0.83, 0.96, 0.89, 0.82, 0.9, 0.83, 0.84, 0.93, 0.95]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 83.247196
| 0.379404
| 1,968
|
O43791
|
Q12809
|
26344095
|
UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
KCNH2
|
MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
|
Homo sapiens
|
Cell membrane
|
Tissue enhanced (bone marrow, pituitary gland)
|
{'Ciliated cells': '4.4', 'Basal respiratory cells': '0.1', 'Club cells': '0.2', 'Ionocytes': '2.6', 'Mucus glandular cells': '0.8', 'Serous glandular cells': '1.1', 'Gastric mucus-secreting cells': '1.2', 'Proximal enterocytes': '0.1', 'Paneth cells': '0.0', 'Distal enterocytes': '0.4', 'Intestinal goblet cells': '0.4', 'Exocrine glandular cells': '-0.373', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.396', 'Breast myoepithelial cells': '0.447', 'Glandular and luminal cells': '0.1', 'Secretory cells': '0.5', 'Basal keratinocytes': '0.1', 'Suprabasal keratinocytes': '0.1', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '0.361', 'Alveolar cells type 2': '-0.394', 'Salivary duct cells': '0.2', 'Ductal cells': '0.392', 'Hepatocytes': '0.051', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.072', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.314', 'Sertoli cells': '0.838', 'Granulosa cells': '25.2', 'Enteroendocrine cells': '6.8', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '0.405', 'Excitatory neurons': '5.0', 'Inhibitory neurons': '13.3', 'Cone photoreceptor cells': '3.4', 'Rod photoreceptor cells': '6.3', 'Bipolar cells': '209.8', 'Horizontal cells': '57.3', 'Astrocytes': '1.5', 'Oligodendrocyte precursor cells': '5.2', 'Oligodendrocytes': '1.6', 'Microglial cells': '2.7', 'Muller glia cells': '2.8', 'Schwann cells': '0.473', 'Spermatogonia': '0.355', 'Spermatocytes': '-0.007', 'Early spermatids': '-0.463', 'Late spermatids': '-0.527', 'Oocytes': '0.7', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.1', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '0.3', 'Lymphatic endothelial cells': '0.2', 'Cardiomyocytes': '0.764', 'Skeletal myocytes': '0.175', 'Smooth muscle cells': '2.9', 'Adipocytes': '0.0', 'Melanocytes': '0.018', 'Fibroblasts': '1.6', 'Peritubular cells': '0.383', 'Endometrial stromal cells': '0.8', 'Ovarian stromal cells': '2.7', 'Undifferentiated cells': '0.7', 'T-cells': '1.0', 'B-cells': '1.6', 'Plasma cells': '1.2', 'Nk-cells': '0.4', 'Granulocytes': '43.3', 'Monocytes': '0.0', 'Macrophages': '0.1', 'Hofbauer cells': '0.1', 'Kupffer cells': '0.3', 'Dendritic cells': '0.0', 'Langerhans cells': '0.176', 'Erythroid cells': '0.325', 'Adipocytes (Subcutaneous)': '-0.314', 'Adipocytes (Visceral)': '-0.322', 'Breast glandular cells (progenitors)': '0.378', 'Adipocytes (Breast)': '-0.438', 'Colon enterocytes': '-0.189', 'Colon enteroendocrine cells': '0.096', 'Enteric glia cells': '0.018', 'Mitotic cells (Colon)': '-0.184', 'Mitotic cells (Heart)': '0.416', 'Podocytes': '0.440', 'Ascending Loop of Henle cells': '0.162', 'Intercalated cells': '0.144', 'Cholangiocyte': '0.275', 'NK-cells (Liver)': '0.007', 'Respiratory ciliated cells': '0.069', 'Mitotic cells (Lung)': '-0.229', 'NK-cells (Lung)': '0.400', 'B-cells (Lung)': '0.173', 'Alpha cells': '0.745', 'Beta cells': '0.743', 'Prostate glandular cells': '-0.285', 'Prostate basal glandular cells': '-0.185', 'Urothelial cells': '-0.183', 'Keratinocyte (other)': '-0.023', 'Keratinocyte (granular)': '-0.201', 'Hair cortex cells': '0.089', 'Inner root sheath cells': '0.028', 'Outer root sheath cells': '0.371', 'Sebaceous gland cells': '0.274', 'Eccrine sweat gland cells': '0.096', 'Adipocytes (Skin)': '0.118', 'Mitotic cells (Skin)': '0.122', 'Parietal cells': '-0.706', 'Chief cells': '-0.570', 'Gastric mucous cells': '-0.667', 'Gastric enteroendocrine cells': '-0.424', 'Mitotic cells (Stomach)': '-0.271', 'Parafollicular cells': '0.364', 'Thyroid glandular cells': '-0.102', 'Mitotic cells (Thyroid)': '0.179', 'Adrenal cortex cells': '0.121', 'Adrenal medulla cells': '0.523', 'Mitotic cells (Adrenal gland)': '0.110', 'Minor salivary glandular cells': '0.328', 'Minor salivary gland ductal cells': '0.193', 'Minor salivary gland basal cells': '-0.444', 'Mitotic cells (Minor salivary gland)': '-0.264', 'Adipocytes (Minor salivary gland)': '-0.269', 'Somatotropes': '0.138', 'Lactotropes': '0.431', 'Gonadotropes': '0.193', 'Corticotropes': '0.527', 'Thyrotropes': '0.477', 'Undifferentiated cells (Pituitary gland)': '-0.279', 'Mitotic cells (Spleen)': '0.029', 'Platelets': '0.116', 'Erythrocytes': '0.364', 'Hematopoietic stem cells': '0.228', 'B-cells (Spleen)': '-0.225', 'NK-cells (Spleen)': '-0.062', 'Amygdala excitatory': '10.5', 'Cerebellar inhibitory': '31.6', 'Cge interneuron': '21.0', 'Deep-layer corticothalamic and 6b': '10.6', 'Deep-layer intratelencephalic': '7.2', 'Deep-layer near-projecting': '13.8', 'Eccentric medium spiny neuron': '14.9', 'Hippocampal ca1-3': '7.8', 'Hippocampal ca4': '5.1', 'Hippocampal dentate gyrus': '2.8', 'Lamp5-lhx6 and chandelier': '26.0', 'Lower rhombic lip': '33.5', 'Mammillary body': '40.8', 'Medium spiny neuron': '12.6', 'Mge interneuron': '19.7', 'Midbrain-derived inhibitory': '45.9', 'Miscellaneous': '5.9', 'Splatter': '23.6', 'Thalamic excitatory': '18.6', 'Upper rhombic lip': '25.1', 'Upper-layer intratelencephalic': '7.9', 'Astrocyte': '5.1', 'Bergmann glia': '2.6', 'Central nervous system macrophage': '1.2', 'Choroid plexus epithelial cell': '5.7', 'Committed oligodendrocyte precursor': '18.4', 'Ependymal cell': '16.9', 'Oligodendrocyte': '1.6', 'Oligodendrocyte precursor cell': '16.9', 'Endothelial cell': '1.0', 'Pericyte': '0.7', 'Vascular associated smooth muscle cell': '1.6', 'Fibroblast': '5.6', 'Leukocyte': '1.3', 'Basophil': '0.2', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '1.5', 'Memory B-cell': '0.0', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.9', 'Memory CD4 T-cell Th17': '3.3', 'Memory CD4 T-cell Th2': '3.3', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '2.4', 'Memory CD4 T-cell TFH': '7.2', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.3', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '3.0', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '4.3'}
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1BYW, 1UJL, 2L0W, 2L1M, 2L4R, 2LE7, 2N7G, 4HP9, 4HQA, 5VA1, 5VA2, 5VA3, 6SYG, 8IO4
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{'Adipose Tissue': 1.412129877076412, 'Adrenal Gland': 3.494408914728682, 'Bladder': 26.476, 'Blood': 2.4555430828848226, 'Blood Vessel': 2.7050206966292136, 'Brain': 20.80104928084784, 'Breast': 0.444625605664488, 'Cervix Uteri': 8.840852631578947, 'Colon': 51.89100064184853, 'Esophagus': 19.53789134948097, 'Fallopian Tube': 19.64788888888889, 'Heart': 31.908627735191637, 'Kidney': 1.2012483146067416, 'Liver': 0.209583407079646, 'Lung': 4.766929930795848, 'Muscle': 0.2580922914072229, 'Nerve': 4.140294668820679, 'Ovary': 7.576756666666666, 'Pancreas': 1.8016966463414632, 'Pituitary': 79.71485512367491, 'Prostate': 21.063791836734698, 'Salivary Gland': 0.999367777777778, 'Skin': 0.4889449994472084, 'Small Intestine': 17.374336898395722, 'Spleen': 3.300861825726141, 'Stomach': 20.97143147632312, 'Testis': 64.41944598337949, 'Thyroid': 0.6695381316998469, 'Uterus': 37.47927464788732, 'Vagina': 6.519141538461539}
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0.47, 0.79, 0.57, 0.37, 0.93, 0.86, 0.35, 0.82, 0.66, 0.64, 0.86, 0.89, 0.89, 0.93, 0.83, 0.87, 0.99, 0.88, 0.99, 0.89, 0.97, 1.0, 0.95, 0.91, 0.98, 0.81, 0.99, 0.98, 0.94, 1.0, 0.88, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 1.0, 0.9, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.97, 0.95, 0.95, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.94, 0.98, 0.95, 0.98, 0.99, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.96, 0.94, 0.79, 0.92, 0.86, 0.94, 0.86, 0.9, 0.92, 0.85, 0.72, 0.8, 0.65, 0.64, 0.59, 0.57, 0.64, 0.43, 0.41, 0.56, 0.6, 0.56, 0.63, 0.64, 0.43, 0.78, 0.88, 0.56, 0.7, 0.77, 0.93, 0.72, 0.98, 0.93, 0.97, 0.86, 0.91, 0.92, 0.82, 0.98, 0.93, 1.0, 0.98, 1.0, 0.98, 0.99, 0.99, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.98, 1.0, 0.98, 0.9, 1.0, 0.96, 0.56, 0.76, 0.48, 0.52, 0.7, 0.54, 0.51, 0.74, 0.65, 0.46, 0.37, 0.58, 0.58, 0.62, 0.6, 0.63, 0.46, 0.74, 0.66, 0.61, 0.61, 0.73, 0.57, 0.54, 0.5, 0.54, 0.59, 0.48, 0.5, 0.55, 0.57, 0.62, 0.59, 0.5, 0.66, 0.72, 0.65, 0.77, 0.76, 0.83, 0.78, 0.82, 0.88, 0.87, 0.95, 0.99, 0.96, 0.96, 0.95, 0.97, 1.0, 0.98, 1.0, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 0.99, 0.98, 0.89, 0.98, 0.94, 0.92, 0.95, 0.94, 0.72, 0.82, 0.69, 0.84, 0.73, 0.57, 0.75, 0.77, 0.82, 0.77, 0.84, 0.97, 0.84, 0.98, 0.94, 0.96, 0.91, 0.97, 0.96, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.98, 0.98, 0.92, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.99, 0.82, 1.0, 0.79, 0.9, 0.98, 0.91, 0.98, 0.98, 0.98, 0.96, 0.96, 0.99]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 62.653546
| 0.618801
| 362
|
O43791
|
Q12834
|
27780719
|
UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
CDC20
|
MAQFAFESDLHSLLQLDAPIPNAPPARWQRKAKEAAGPAPSPMRAANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRYIPHRSAAQMEVASFLLSKENQPENSQTPTKKEHQKAWALNLNGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQGIR
|
Homo sapiens
|
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Chromosome, centromere, kinetochore, Cytoplasm, cytoskeleton, spindle pole
|
Tissue enhanced (bone marrow, lymphoid tissue, testis)
|
{'Ciliated cells': '10.7', 'Basal respiratory cells': '18.1', 'Club cells': '5.1', 'Ionocytes': '13.6', 'Mucus glandular cells': '3.0', 'Serous glandular cells': '7.7', 'Gastric mucus-secreting cells': '13.0', 'Proximal enterocytes': '2.5', 'Paneth cells': '1.5', 'Distal enterocytes': '3.3', 'Intestinal goblet cells': '13.7', 'Exocrine glandular cells': '-0.309', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.389', 'Breast myoepithelial cells': '0.180', 'Glandular and luminal cells': '4.8', 'Secretory cells': '0.8', 'Basal keratinocytes': '23.5', 'Suprabasal keratinocytes': '12.1', 'Basal squamous epithelial cells': '16.6', 'Squamous epithelial cells': '45.2', 'Alveolar cells type 1': '-0.269', 'Alveolar cells type 2': '0.212', 'Salivary duct cells': '5.7', 'Ductal cells': '0.460', 'Hepatocytes': '0.320', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.491', 'Distal tubular cells': '3.1', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.109', 'Sertoli cells': '-0.447', 'Granulosa cells': '6.6', 'Enteroendocrine cells': '5.1', 'Pancreatic endocrine cells': '30.6', 'Leydig cells': '-0.493', 'Excitatory neurons': '0.1', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '2.8', 'Bipolar cells': '0.4', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '1.5', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.072', 'Spermatogonia': '-0.113', 'Spermatocytes': '0.279', 'Early spermatids': '0.741', 'Late spermatids': '0.592', 'Oocytes': '12.5', 'Cytotrophoblasts': '73.3', 'Syncytiotrophoblasts': '11.3', 'Extravillous trophoblasts': '148.6', 'Endothelial cells': '3.3', 'Lymphatic endothelial cells': '0.3', 'Cardiomyocytes': '0.471', 'Skeletal myocytes': '-0.141', 'Smooth muscle cells': '3.1', 'Adipocytes': '2.0', 'Melanocytes': '0.465', 'Fibroblasts': '9.2', 'Peritubular cells': '-0.419', 'Endometrial stromal cells': '1.7', 'Ovarian stromal cells': '0.4', 'Undifferentiated cells': '76.0', 'T-cells': '4.6', 'B-cells': '1.6', 'Plasma cells': '49.4', 'Nk-cells': '1.2', 'Granulocytes': '2.0', 'Monocytes': '0.2', 'Macrophages': '7.0', 'Hofbauer cells': '29.9', 'Kupffer cells': '5.8', 'Dendritic cells': '0.4', 'Langerhans cells': '0.175', 'Erythroid cells': '0.139', 'Adipocytes (Subcutaneous)': '0.228', 'Adipocytes (Visceral)': '0.094', 'Breast glandular cells (progenitors)': '0.372', 'Adipocytes (Breast)': '-0.147', 'Colon enterocytes': '0.377', 'Colon enteroendocrine cells': '-0.181', 'Enteric glia cells': '-0.260', 'Mitotic cells (Colon)': '0.682', 'Mitotic cells (Heart)': '0.755', 'Podocytes': '-0.128', 'Ascending Loop of Henle cells': '0.116', 'Intercalated cells': '-0.141', 'Cholangiocyte': '0.317', 'NK-cells (Liver)': '-0.127', 'Respiratory ciliated cells': '0.052', 'Mitotic cells (Lung)': '0.870', 'NK-cells (Lung)': '-0.178', 'B-cells (Lung)': '-0.028', 'Alpha cells': '0.195', 'Beta cells': '0.079', 'Prostate glandular cells': '-0.077', 'Prostate basal glandular cells': '0.267', 'Urothelial cells': '0.231', 'Keratinocyte (other)': '0.296', 'Keratinocyte (granular)': '-0.055', 'Hair cortex cells': '0.020', 'Inner root sheath cells': '0.146', 'Outer root sheath cells': '0.145', 'Sebaceous gland cells': '0.172', 'Eccrine sweat gland cells': '-0.109', 'Adipocytes (Skin)': '-0.136', 'Mitotic cells (Skin)': '0.843', 'Parietal cells': '0.201', 'Chief cells': '0.163', 'Gastric mucous cells': '0.628', 'Gastric enteroendocrine cells': '0.253', 'Mitotic cells (Stomach)': '0.912', 'Parafollicular cells': '0.005', 'Thyroid glandular cells': '0.284', 'Mitotic cells (Thyroid)': '0.288', 'Adrenal cortex cells': '0.390', 'Adrenal medulla cells': '0.126', 'Mitotic cells (Adrenal gland)': '0.899', 'Minor salivary glandular cells': '0.070', 'Minor salivary gland ductal cells': '-0.179', 'Minor salivary gland basal cells': '0.716', 'Mitotic cells (Minor salivary gland)': '0.866', 'Adipocytes (Minor salivary gland)': '0.224', 'Somatotropes': '-0.263', 'Lactotropes': '-0.135', 'Gonadotropes': '0.036', 'Corticotropes': '-0.079', 'Thyrotropes': '-0.010', 'Undifferentiated cells (Pituitary gland)': '0.345', 'Mitotic cells (Spleen)': '0.905', 'Platelets': '0.216', 'Erythrocytes': '0.290', 'Hematopoietic stem cells': '0.378', 'B-cells (Spleen)': '-0.103', 'NK-cells (Spleen)': '-0.290', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.1', 'Cge interneuron': '0.1', 'Deep-layer corticothalamic and 6b': '0.1', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.1', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.1', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.1', 'Mge interneuron': '0.2', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.1', 'Splatter': '0.1', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.3', 'Upper-layer intratelencephalic': '0.2', 'Astrocyte': '0.1', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.2', 'Choroid plexus epithelial cell': '0.7', 'Committed oligodendrocyte precursor': '0.6', 'Ependymal cell': '0.2', 'Oligodendrocyte': '2.7', 'Oligodendrocyte precursor cell': '0.1', 'Endothelial cell': '0.1', 'Pericyte': '0.2', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.1', 'Leukocyte': '0.1', 'Basophil': '0.1', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.5', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '0.3', 'T-reg': '8.6', 'GdT-cell': '0.3', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '3.2', 'Naive CD4 T-cell': '0.9', 'Memory CD8 T-cell': '3.5', 'Naive CD8 T-cell': '1.5', 'Memory B-cell': '4.2', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '1.0', 'Myeloid DC': '1.9', 'NK-cell': '1.7', 'Total PBMC': '7.3', 'Vd2 gdTCR': '0.7', 'Memory CD4 T-cell Th1\\/Th17': '1.0', 'Memory CD4 T-cell Th17': '1.1', 'Memory CD4 T-cell Th2': '1.4', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '2.1', 'Memory CD4 T-cell TFH': '0.6', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '2.4', 'Effector memory CD8 T-cell': '11.2', 'Terminal effector memory CD8 T-cell': '1.0', 'Non-switched memory B-cell': '1.7', 'Plasmablast': '122.6', 'Switched memory B-cell': '6.5', 'Exhausted memory B-cell': '14.6', 'Progenitor cell': '1.7', 'Memory T-reg': '5.5', 'Naive CD4 T-cell activated': '0.6', 'Naive CD8 T-cell activated': '1.0', 'Naive T-reg': '0.8'}
|
4GGA, 4GGC, 4GGD, 4N14, 5G04, 5KHR, 5KHU, 5LCW, 6F0X, 6Q6G, 6Q6H
|
{'Adipose Tissue': 2.2786306644518275, 'Adrenal Gland': 2.048905968992248, 'Bladder': 1.9396333333333335, 'Blood': 29.0616601722282, 'Blood Vessel': 1.144201647940075, 'Brain': 0.7357121271763816, 'Breast': 2.6461001960784314, 'Cervix Uteri': 3.253421052631579, 'Colon': 7.793533645699615, 'Esophagus': 14.337347557093423, 'Fallopian Tube': 1.1193666666666668, 'Heart': 0.671262768873403, 'Kidney': 2.6050022471910115, 'Liver': 1.3700479203539824, 'Lung': 4.880240830449827, 'Muscle': 0.2785133748443337, 'Nerve': 2.5705977382875607, 'Ovary': 1.4988983333333332, 'Pancreas': 0.459626006097561, 'Pituitary': 0.6490177738515901, 'Prostate': 1.693611836734694, 'Salivary Gland': 6.318791358024691, 'Skin': 39.24435245992261, 'Small Intestine': 14.948275401069518, 'Spleen': 16.867082987551868, 'Stomach': 7.753507520891365, 'Testis': 102.45542936288088, 'Thyroid': 3.5809618683001534, 'Uterus': 1.1763063380281689, 'Vagina': 11.839822435897435}
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[55.9, 69.13, 65.69, 71.33, 76.11, 78.06, 75.63, 74.58, 74.13, 73.88, 73.07, 69.48, 67.16, 68.04, 59.15, 53.99, 59.53, 53.69, 52.3, 54.45, 56.23, 56.36, 56.11, 64.96, 73.56, 70.0, 68.8, 73.03, 77.53, 72.34, 69.87, 67.54, 69.67, 64.48, 60.2, 54.89, 45.22, 45.55, 37.73, 44.61, 41.45, 41.12, 46.25, 38.71, 36.22, 42.83, 39.02, 40.94, 42.63, 42.38, 43.25, 43.77, 43.76, 42.94, 44.75, 47.37, 43.88, 43.41, 42.54, 46.84, 41.83, 40.56, 42.06, 43.65, 44.15, 42.79, 42.41, 39.9, 42.21, 38.81, 41.63, 43.22, 47.68, 47.9, 42.05, 43.18, 49.7, 52.19, 52.64, 55.92, 52.04, 57.9, 59.76, 67.23, 69.45, 68.9, 75.37, 76.0, 75.63, 77.34, 76.02, 77.23, 79.69, 78.89, 75.27, 74.2, 69.12, 62.43, 61.5, 52.63, 53.04, 52.78, 50.38, 47.01, 55.97, 57.48, 67.36, 76.44, 74.56, 74.52, 79.94, 81.68, 78.6, 81.92, 83.57, 81.68, 82.47, 85.94, 84.88, 83.73, 81.97, 83.58, 82.73, 80.44, 78.91, 79.2, 83.26, 84.14, 85.62, 85.57, 87.62, 87.85, 86.25, 85.06, 86.98, 81.85, 80.53, 82.36, 77.81, 69.0, 72.68, 66.21, 63.56, 55.74, 53.88, 50.94, 55.12, 56.12, 50.6, 51.38, 45.79, 40.93, 47.55, 48.7, 51.01, 57.1, 49.19, 55.55, 56.01, 49.98, 54.02, 53.11, 56.05, 62.5, 71.03, 88.06, 89.81, 93.83, 94.36, 94.42, 96.38, 97.61, 96.17, 97.05, 98.25, 98.34, 98.41, 98.3, 98.13, 97.68, 98.53, 98.62, 98.48, 98.45, 98.26, 98.73, 98.83, 98.84, 98.82, 98.76, 98.87, 98.73, 98.52, 97.63, 97.49, 98.15, 98.68, 98.65, 98.87, 98.83, 98.85, 98.7, 98.57, 98.44, 98.7, 98.83, 98.77, 98.71, 98.58, 97.86, 97.02, 95.52, 96.72, 96.39, 97.88, 98.07, 98.2, 98.41, 98.51, 98.53, 98.32, 98.24, 95.79, 96.33, 95.65, 95.8, 97.9, 98.77, 98.87, 98.87, 98.9, 98.92, 98.95, 98.86, 98.66, 97.79, 96.41, 97.53, 97.75, 98.69, 98.88, 98.94, 98.94, 98.91, 98.91, 98.69, 98.45, 98.62, 98.77, 98.89, 98.83, 98.83, 98.81, 98.48, 97.88, 96.23, 97.35, 97.55, 98.12, 98.49, 98.35, 98.58, 98.57, 98.8, 98.68, 98.63, 98.81, 98.43, 98.67, 98.76, 98.92, 98.79, 98.92, 98.95, 98.92, 98.87, 98.64, 98.28, 98.43, 98.8, 98.91, 98.94, 98.96, 98.93, 98.94, 98.84, 98.59, 98.67, 98.81, 98.94, 98.93, 98.89, 98.9, 98.77, 98.55, 98.51, 98.58, 98.45, 98.61, 98.77, 98.82, 98.63, 98.7, 98.71, 98.74, 98.43, 98.21, 98.84, 98.65, 98.65, 98.82, 98.93, 98.78, 98.78, 98.93, 98.91, 98.85, 98.69, 97.69, 97.5, 97.73, 98.18, 98.65, 98.9, 98.93, 98.94, 98.91, 98.76, 98.81, 98.7, 98.67, 98.82, 98.94, 98.93, 98.92, 98.85, 98.43, 98.02, 97.68, 97.13, 95.75, 93.94, 94.4, 96.83, 98.16, 98.26, 98.44, 98.37, 98.68, 98.84, 98.82, 98.76, 98.65, 98.68, 98.35, 97.43, 98.43, 98.86, 98.88, 98.84, 98.88, 98.89, 98.85, 98.68, 97.92, 97.88, 98.18, 97.42, 98.38, 98.75, 98.91, 98.9, 98.94, 98.8, 98.41, 96.97, 95.4, 95.1, 97.2, 97.53, 98.55, 98.85, 98.86, 98.87, 98.85, 98.69, 98.57, 97.9, 98.11, 98.26, 98.55, 98.55, 98.44, 97.94, 98.51, 98.21, 97.56, 95.94, 94.09, 96.11, 97.6, 98.67, 98.12, 98.55, 98.84, 98.88, 98.74, 97.84, 95.85, 94.34, 94.72, 96.79, 98.17, 98.27, 98.78, 98.8, 98.62, 98.7, 96.64, 93.02, 92.75, 93.94, 97.22, 98.02, 98.69, 98.45, 98.39, 98.29, 97.68, 98.16, 97.75, 97.55, 97.66, 96.19, 96.05, 95.89, 96.13, 96.75, 97.6, 97.07, 95.64, 98.21, 97.71, 97.99, 98.24, 98.65, 98.66, 97.93, 98.84, 98.77, 98.64, 98.28, 97.04, 94.92, 96.65, 96.67, 98.17, 98.78, 98.78, 98.78, 98.77, 98.78, 98.57, 98.35, 98.61, 98.66, 98.65, 98.7, 98.56, 98.49, 96.86, 96.62, 96.59, 92.53, 88.33, 79.8, 77.0, 75.08, 76.45, 77.67, 76.54, 77.21, 73.62, 75.37, 74.55, 72.89, 69.09, 61.2, 57.64, 60.49, 53.98, 68.12, 71.17, 74.04, 75.23, 68.96, 80.55, 67.87, 55.09]
|
[0.86, 0.74, 0.77, 0.73, 0.42, 0.64, 0.61, 0.46, 0.59, 0.42, 0.62, 0.55, 0.76, 0.67, 0.59, 0.8, 0.83, 0.7, 0.82, 0.66, 0.91, 0.93, 0.54, 0.81, 0.51, 0.37, 0.79, 0.8, 0.54, 0.5, 0.67, 0.54, 0.81, 0.78, 0.75, 0.72, 0.74, 0.94, 0.9, 0.94, 0.9, 0.99, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 0.97, 0.94, 0.94, 0.85, 0.91, 0.88, 0.9, 0.93, 0.94, 0.86, 0.93, 0.98, 0.9, 0.88, 0.79, 0.62, 0.66, 0.71, 0.79, 0.77, 0.48, 0.68, 0.48, 0.85, 0.45, 0.42, 0.57, 0.61, 0.58, 0.58, 0.5, 0.65, 0.82, 0.73, 0.64, 0.85, 0.95, 0.97, 0.75, 0.6, 0.52, 0.7, 0.64, 0.64, 0.55, 0.65, 0.55, 0.65, 0.39, 0.4, 0.6, 0.14, 0.47, 0.82, 0.77, 0.5, 0.67, 0.55, 0.12, 0.52, 0.83, 0.7, 0.45, 0.88, 0.98, 0.87, 0.94, 0.87, 0.88, 0.65, 0.95, 0.89, 0.96, 0.94, 0.71, 0.65, 0.97, 0.91, 0.75, 0.92, 0.6, 0.68, 0.75, 0.76, 0.52, 0.87, 0.94, 0.33, 0.9, 0.94, 0.43, 0.91, 0.83, 0.56, 0.94, 0.53, 0.94, 0.96, 0.44, 0.98, 0.2, 0.88, 0.17, 0.32, 0.63, 0.77, 0.19, 0.62, 0.54, 0.53, 0.24, 0.8, 0.01, 0.6, 0.63, 0.07, 0.35, 0.51, 0.23, 0.1, 0.3, 0.02, 0.21, 0.04, 0.1, 0.24, 0.1, 0.01, 0.48, 0.6, 0.24, 0.23, 0.0, 0.0, 0.12, 0.01, 0.11, 0.24, 0.28, 0.05, 0.0, 0.34, 0.04, 0.1, 0.21, 0.21, 0.73, 0.59, 0.38, 0.6, 0.73, 0.38, 0.39, 0.05, 0.06, 0.64, 0.13, 0.84, 0.65, 0.95, 0.79, 0.25, 0.13, 0.01, 0.0, 0.0, 0.06, 0.06, 0.06, 0.13, 0.8, 0.71, 0.18, 0.53, 0.34, 0.0, 0.0, 0.0, 0.0, 0.0, 0.25, 0.36, 0.07, 0.18, 0.01, 0.02, 0.05, 0.13, 0.16, 0.17, 0.93, 0.75, 0.47, 0.62, 0.4, 0.49, 0.21, 0.41, 0.01, 0.62, 0.34, 0.1, 0.78, 0.27, 0.03, 0.0, 0.0, 0.01, 0.11, 0.11, 0.14, 0.3, 0.65, 0.44, 0.22, 0.0, 0.0, 0.0, 0.0, 0.0, 0.47, 0.26, 0.0, 0.34, 0.0, 0.05, 0.04, 0.0, 0.11, 0.15, 0.66, 0.49, 0.77, 0.82, 0.12, 0.45, 0.55, 0.09, 0.39, 0.0, 0.57, 0.27, 0.09, 0.78, 0.46, 0.07, 0.0, 0.0, 0.02, 0.1, 0.36, 0.07, 0.07, 0.67, 0.44, 0.16, 0.45, 0.12, 0.0, 0.0, 0.0, 0.0, 0.0, 0.26, 0.18, 0.29, 0.24, 0.0, 0.01, 0.01, 0.0, 0.18, 0.48, 0.65, 0.58, 0.64, 0.99, 0.8, 0.34, 0.22, 0.59, 0.3, 0.53, 0.24, 0.54, 0.03, 0.6, 0.4, 0.03, 0.55, 0.09, 0.1, 0.0, 0.05, 0.01, 0.04, 0.03, 0.07, 0.03, 0.55, 0.29, 0.45, 0.49, 0.27, 0.06, 0.0, 0.0, 0.0, 0.0, 0.0, 0.06, 0.42, 0.52, 0.06, 0.19, 0.28, 0.02, 0.16, 0.02, 0.0, 0.28, 0.06, 0.59, 0.62, 0.24, 0.38, 0.38, 0.51, 0.28, 0.55, 0.2, 0.32, 0.08, 0.61, 0.05, 0.13, 0.0, 0.01, 0.13, 0.02, 0.09, 0.05, 0.0, 0.51, 0.11, 0.2, 0.46, 0.03, 0.02, 0.0, 0.01, 0.0, 0.0, 0.0, 0.65, 0.41, 0.29, 0.1, 0.05, 0.0, 0.03, 0.0, 0.02, 0.38, 0.14, 0.85, 0.72, 0.09, 0.47, 0.41, 0.14, 0.2, 0.3, 0.02, 0.38, 0.41, 0.06, 0.71, 0.36, 0.28, 0.0, 0.03, 0.14, 0.04, 0.07, 0.27, 0.09, 0.41, 0.48, 0.04, 0.04, 0.12, 0.0, 0.01, 0.0, 0.01, 0.0, 0.18, 0.21, 0.46, 0.17, 0.02, 0.14, 0.04, 0.02, 0.4, 0.06, 0.0, 0.4, 0.16, 0.64, 0.66, 0.52, 0.5, 0.52, 0.67, 0.66, 0.48, 0.45, 0.75, 0.6, 0.56, 0.62, 0.81, 0.85, 0.57, 0.9, 0.84, 0.79, 0.82, 0.85, 0.67, 1.0, 0.9]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 84.601884
| 0.437455
| 1,590
|
O43791
|
Q12888
|
34144977
|
UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
TP53BP1
|
MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPAKRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMATTSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH
|
Homo sapiens
|
Nucleus, Chromosome, Chromosome, centromere, kinetochore
|
Low tissue specificity
|
{'Ciliated cells': '48.5', 'Basal respiratory cells': '13.4', 'Club cells': '18.8', 'Ionocytes': '14.7', 'Mucus glandular cells': '30.6', 'Serous glandular cells': '11.0', 'Gastric mucus-secreting cells': '14.7', 'Proximal enterocytes': '1.5', 'Paneth cells': '4.9', 'Distal enterocytes': '8.1', 'Intestinal goblet cells': '15.0', 'Exocrine glandular cells': '-0.521', 'Basal prostatic cells': '16.1', 'Prostatic glandular cells': '29.5', 'Breast glandular cells': '0.578', 'Breast myoepithelial cells': '0.595', 'Glandular and luminal cells': '23.0', 'Secretory cells': '18.7', 'Basal keratinocytes': '9.6', 'Suprabasal keratinocytes': '9.4', 'Basal squamous epithelial cells': '12.2', 'Squamous epithelial cells': '13.9', 'Alveolar cells type 1': '0.038', 'Alveolar cells type 2': '-0.303', 'Salivary duct cells': '30.6', 'Ductal cells': '0.622', 'Hepatocytes': '0.363', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.181', 'Distal tubular cells': '3.1', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.437', 'Sertoli cells': '0.399', 'Granulosa cells': '23.4', 'Enteroendocrine cells': '17.3', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '0.329', 'Excitatory neurons': '64.0', 'Inhibitory neurons': '78.5', 'Cone photoreceptor cells': '23.8', 'Rod photoreceptor cells': '57.4', 'Bipolar cells': '24.1', 'Horizontal cells': '42.2', 'Astrocytes': '50.5', 'Oligodendrocyte precursor cells': '59.0', 'Oligodendrocytes': '46.9', 'Microglial cells': '17.0', 'Muller glia cells': '12.4', 'Schwann cells': '0.262', 'Spermatogonia': '0.584', 'Spermatocytes': '0.587', 'Early spermatids': '-0.187', 'Late spermatids': '-0.330', 'Oocytes': '2.2', 'Cytotrophoblasts': '12.9', 'Syncytiotrophoblasts': '18.4', 'Extravillous trophoblasts': '11.3', 'Endothelial cells': '14.6', 'Lymphatic endothelial cells': '24.6', 'Cardiomyocytes': '0.621', 'Skeletal myocytes': '0.057', 'Smooth muscle cells': '18.4', 'Adipocytes': '10.0', 'Melanocytes': '0.094', 'Fibroblasts': '22.0', 'Peritubular cells': '0.293', 'Endometrial stromal cells': '39.0', 'Ovarian stromal cells': '21.1', 'Undifferentiated cells': '10.9', 'T-cells': '16.5', 'B-cells': '19.5', 'Plasma cells': '14.0', 'Nk-cells': '9.8', 'Granulocytes': '28.5', 'Monocytes': '6.1', 'Macrophages': '10.1', 'Hofbauer cells': '9.3', 'Kupffer cells': '4.3', 'Dendritic cells': '15.4', 'Langerhans cells': '0.175', 'Erythroid cells': '0.095', 'Adipocytes (Subcutaneous)': '-0.320', 'Adipocytes (Visceral)': '-0.327', 'Breast glandular cells (progenitors)': '0.425', 'Adipocytes (Breast)': '-0.491', 'Colon enterocytes': '-0.140', 'Colon enteroendocrine cells': '0.297', 'Enteric glia cells': '0.080', 'Mitotic cells (Colon)': '-0.105', 'Mitotic cells (Heart)': '0.495', 'Podocytes': '-0.117', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.014', 'Cholangiocyte': '0.408', 'NK-cells (Liver)': '-0.193', 'Respiratory ciliated cells': '0.342', 'Mitotic cells (Lung)': '0.095', 'NK-cells (Lung)': '0.338', 'B-cells (Lung)': '0.213', 'Alpha cells': '0.470', 'Beta cells': '0.374', 'Prostate glandular cells': '-0.062', 'Prostate basal glandular cells': '0.296', 'Urothelial cells': '0.266', 'Keratinocyte (other)': '-0.043', 'Keratinocyte (granular)': '-0.331', 'Hair cortex cells': '0.173', 'Inner root sheath cells': '0.211', 'Outer root sheath cells': '0.452', 'Sebaceous gland cells': '0.108', 'Eccrine sweat gland cells': '0.269', 'Adipocytes (Skin)': '0.109', 'Mitotic cells (Skin)': '0.396', 'Parietal cells': '-0.658', 'Chief cells': '-0.622', 'Gastric mucous cells': '-0.407', 'Gastric enteroendocrine cells': '-0.409', 'Mitotic cells (Stomach)': '0.018', 'Parafollicular cells': '0.115', 'Thyroid glandular cells': '0.453', 'Mitotic cells (Thyroid)': '-0.040', 'Adrenal cortex cells': '0.325', 'Adrenal medulla cells': '0.160', 'Mitotic cells (Adrenal gland)': '0.247', 'Minor salivary glandular cells': '0.487', 'Minor salivary gland ductal cells': '0.425', 'Minor salivary gland basal cells': '0.021', 'Mitotic cells (Minor salivary gland)': '0.092', 'Adipocytes (Minor salivary gland)': '0.045', 'Somatotropes': '0.356', 'Lactotropes': '0.349', 'Gonadotropes': '0.181', 'Corticotropes': '0.024', 'Thyrotropes': '0.224', 'Undifferentiated cells (Pituitary gland)': '-0.136', 'Mitotic cells (Spleen)': '-0.142', 'Platelets': '-0.263', 'Erythrocytes': '-0.098', 'Hematopoietic stem cells': '-0.322', 'B-cells (Spleen)': '0.327', 'NK-cells (Spleen)': '0.319', 'Amygdala excitatory': '116.0', 'Cerebellar inhibitory': '157.1', 'Cge interneuron': '127.8', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '107.9', 'Deep-layer near-projecting': '119.4', 'Eccentric medium spiny neuron': '114.9', 'Hippocampal ca1-3': '114.2', 'Hippocampal ca4': '95.1', 'Hippocampal dentate gyrus': '118.7', 'Lamp5-lhx6 and chandelier': '126.5', 'Lower rhombic lip': '92.1', 'Mammillary body': '142.6', 'Medium spiny neuron': '119.9', 'Mge interneuron': '129.9', 'Midbrain-derived inhibitory': '109.3', 'Miscellaneous': '110.5', 'Splatter': '115.2', 'Thalamic excitatory': '111.8', 'Upper rhombic lip': '121.5', 'Upper-layer intratelencephalic': '107.5', 'Astrocyte': '119.7', 'Bergmann glia': '104.3', 'Central nervous system macrophage': '49.8', 'Choroid plexus epithelial cell': '189.6', 'Committed oligodendrocyte precursor': '83.9', 'Ependymal cell': '198.6', 'Oligodendrocyte': '76.7', 'Oligodendrocyte precursor cell': '112.9', 'Endothelial cell': '46.5', 'Pericyte': '74.9', 'Vascular associated smooth muscle cell': '58.8', 'Fibroblast': '103.0', 'Leukocyte': '41.6', 'Basophil': '26.8', 'Eosinophil': '1.0', 'Neutrophil': '15.2', 'Classical monocyte': '5.8', 'Non-classical monocyte': '9.5', 'Intermediate monocyte': '7.3', 'T-reg': '23.7', 'GdT-cell': '1.6', 'MAIT T-cell': '22.1', 'Memory CD4 T-cell': '1.6', 'Naive CD4 T-cell': '24.6', 'Memory CD8 T-cell': '1.6', 'Naive CD8 T-cell': '21.3', 'Memory B-cell': '1.9', 'Naive B-cell': '22.5', 'Plasmacytoid DC': '25.4', 'Myeloid DC': '9.3', 'NK-cell': '15.4', 'Total PBMC': '11.2', 'Vd2 gdTCR': '20.1', 'Memory CD4 T-cell Th1\\/Th17': '22.7', 'Memory CD4 T-cell Th17': '25.7', 'Memory CD4 T-cell Th2': '27.7', 'Non-Vd2 gdTCR': '15.6', 'Memory CD4 T-cell Th1': '22.0', 'Memory CD4 T-cell TFH': '24.4', 'Terminal effector memory CD4 T-cell': '25.6', 'Central memory CD8 T-cell': '26.5', 'Effector memory CD8 T-cell': '19.7', 'Terminal effector memory CD8 T-cell': '15.6', 'Non-switched memory B-cell': '30.8', 'Plasmablast': '24.5', 'Switched memory B-cell': '21.1', 'Exhausted memory B-cell': '21.4', 'Progenitor cell': '58.8', 'Memory T-reg': '20.4', 'Naive CD4 T-cell activated': '43.1', 'Naive CD8 T-cell activated': '55.4', 'Naive T-reg': '18.5'}
|
1GZH, 1KZY, 1XNI, 2G3R, 2IG0, 2LVM, 2MWO, 2MWP, 3LGF, 3LGL, 3LH0, 4CRI, 4RG2, 4X34, 5ECG, 5J26, 5KGF, 5Z78, 5ZCJ, 6CO1, 6CO2, 6IU7, 6IUA, 6MXX, 6MXY, 6MXZ, 6MY0, 6RML, 6RMM, 6UPT, 6VA5, 6VIP, 7LIN, 7LIO, 7YQK, 8EOM, 8F0W, 8HKW, 8SWJ, 8U4U
|
{'Adipose Tissue': 12.33118023255814, 'Adrenal Gland': 14.912821705426357, 'Bladder': 18.81195238095238, 'Blood': 5.467300505920344, 'Blood Vessel': 14.282683895131088, 'Brain': 15.035925435276306, 'Breast': 15.194943355119824, 'Cervix Uteri': 33.606842105263155, 'Colon': 15.727594351732993, 'Esophagus': 11.28569480968858, 'Fallopian Tube': 21.682222222222222, 'Heart': 6.906203716608594, 'Kidney': 8.896449438202247, 'Liver': 2.5099526548672566, 'Lung': 13.963602076124568, 'Muscle': 5.1683438356164375, 'Nerve': 17.968012924071083, 'Ovary': 29.246611111111115, 'Pancreas': 5.037862804878049, 'Pituitary': 49.16314487632509, 'Prostate': 19.537685714285715, 'Salivary Gland': 13.306851851851851, 'Skin': 14.490668325041458, 'Small Intestine': 11.859352941176471, 'Spleen': 12.127195020746887, 'Stomach': 9.6295069637883, 'Testis': 30.944847645429363, 'Thyroid': 29.60859571209801, 'Uterus': 28.66387323943662, 'Vagina': 19.418801282051284}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
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0.25, 0.24, 0.13, 0.03, 0.21, 0.19, 0.39, 0.17, 0.0, 0.03, 0.0, 0.0, 0.01, 0.04, 0.36, 0.38, 0.08, 0.1, 0.0, 0.0, 0.17, 0.08, 0.24, 0.0, 0.0, 0.15, 0.31, 0.0, 0.02, 0.48, 0.52, 0.29, 0.68, 0.37, 0.32, 0.45, 0.14, 0.75, 0.82, 0.21, 0.32, 0.08, 0.24, 0.05, 0.05, 0.19, 0.01, 0.13, 0.59, 0.55, 0.53, 0.54, 0.39, 0.11, 0.77, 0.21, 0.66, 0.82, 0.29, 0.95, 0.45, 0.04, 0.0, 0.51, 0.73, 0.03, 0.31, 0.0, 0.01, 0.0, 0.01, 0.0, 0.56, 0.48, 0.43, 0.72, 0.44, 0.03, 0.01, 0.45, 0.13, 0.0, 0.16, 0.29, 0.0, 0.0, 0.49, 0.17, 0.0, 0.16, 0.11, 0.55, 0.41, 0.2, 0.62, 0.37, 0.12, 0.38, 0.13, 0.75, 0.33, 0.83, 0.57, 0.89, 0.92, 0.26, 0.52, 0.09, 0.75, 0.59, 0.16, 0.34, 0.0, 0.01, 0.0, 0.01, 0.15, 0.63, 0.28, 0.12, 0.2, 0.49, 0.56, 0.1, 0.26, 0.66, 0.45, 0.0, 0.74, 0.76, 0.55, 0.84, 0.09, 0.21, 0.24, 0.0, 0.12, 0.16, 0.07, 0.0, 0.0, 0.01, 0.0, 0.0, 0.01, 0.04, 0.19, 0.17, 0.64, 0.43, 0.11, 0.38, 0.26, 0.9, 0.55, 0.21, 0.59, 0.12, 0.02, 0.57, 0.17, 0.64, 0.35, 0.67, 0.32, 0.9]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 44.005948
| 0.806141
| 105
|
O43791
|
Q12906
|
nan, 31772275
|
degron_data, UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
ILF3
|
MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQAESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPTWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVHAPIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGGGGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQGKQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMNYQYR
|
Homo sapiens
|
Nucleus, nucleolus, Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '68.9', 'Basal respiratory cells': '61.0', 'Club cells': '59.2', 'Ionocytes': '68.8', 'Mucus glandular cells': '76.3', 'Serous glandular cells': '54.8', 'Gastric mucus-secreting cells': '93.1', 'Proximal enterocytes': '37.6', 'Paneth cells': '59.7', 'Distal enterocytes': '51.1', 'Intestinal goblet cells': '62.3', 'Exocrine glandular cells': '-0.731', 'Basal prostatic cells': '54.7', 'Prostatic glandular cells': '86.3', 'Breast glandular cells': '0.587', 'Breast myoepithelial cells': '0.495', 'Glandular and luminal cells': '102.0', 'Secretory cells': '79.3', 'Basal keratinocytes': '89.0', 'Suprabasal keratinocytes': '74.5', 'Basal squamous epithelial cells': '107.0', 'Squamous epithelial cells': '106.7', 'Alveolar cells type 1': '0.035', 'Alveolar cells type 2': '-0.132', 'Salivary duct cells': '78.1', 'Ductal cells': '0.636', 'Hepatocytes': '0.160', 'Cholangiocytes': '53.4', 'Proximal tubular cells': '0.085', 'Distal tubular cells': '24.6', 'Collecting duct cells': '37.0', 'Mesothelial cells': '0.249', 'Sertoli cells': '0.421', 'Granulosa cells': '75.3', 'Enteroendocrine cells': '73.4', 'Pancreatic endocrine cells': '71.3', 'Leydig cells': '0.427', 'Excitatory neurons': '23.6', 'Inhibitory neurons': '32.5', 'Cone photoreceptor cells': '73.1', 'Rod photoreceptor cells': '88.2', 'Bipolar cells': '86.9', 'Horizontal cells': '70.5', 'Astrocytes': '32.5', 'Oligodendrocyte precursor cells': '29.7', 'Oligodendrocytes': '26.8', 'Microglial cells': '23.3', 'Muller glia cells': '63.2', 'Schwann cells': '0.058', 'Spermatogonia': '0.524', 'Spermatocytes': '0.549', 'Early spermatids': '-0.008', 'Late spermatids': '-0.477', 'Oocytes': '39.7', 'Cytotrophoblasts': '95.9', 'Syncytiotrophoblasts': '73.3', 'Extravillous trophoblasts': '107.1', 'Endothelial cells': '67.0', 'Lymphatic endothelial cells': '55.9', 'Cardiomyocytes': '0.536', 'Skeletal myocytes': '-0.363', 'Smooth muscle cells': '70.0', 'Adipocytes': '63.9', 'Melanocytes': '0.087', 'Fibroblasts': '71.2', 'Peritubular cells': '0.391', 'Endometrial stromal cells': '103.4', 'Ovarian stromal cells': '95.0', 'Undifferentiated cells': '104.0', 'T-cells': '97.8', 'B-cells': '93.8', 'Plasma cells': '114.9', 'Nk-cells': '93.2', 'Granulocytes': '83.2', 'Monocytes': '73.3', 'Macrophages': '77.4', 'Hofbauer cells': '69.0', 'Kupffer cells': '51.7', 'Dendritic cells': '93.9', 'Langerhans cells': '0.078', 'Erythroid cells': '-0.121', 'Adipocytes (Subcutaneous)': '-0.253', 'Adipocytes (Visceral)': '-0.201', 'Breast glandular cells (progenitors)': '0.381', 'Adipocytes (Breast)': '-0.522', 'Colon enterocytes': '-0.107', 'Colon enteroendocrine cells': '0.240', 'Enteric glia cells': '0.082', 'Mitotic cells (Colon)': '-0.054', 'Mitotic cells (Heart)': '0.469', 'Podocytes': '-0.127', 'Ascending Loop of Henle cells': '0.420', 'Intercalated cells': '-0.060', 'Cholangiocyte': '0.317', 'NK-cells (Liver)': '-0.222', 'Respiratory ciliated cells': '0.058', 'Mitotic cells (Lung)': '-0.091', 'NK-cells (Lung)': '0.311', 'B-cells (Lung)': '0.168', 'Alpha cells': '0.403', 'Beta cells': '0.236', 'Prostate glandular cells': '0.047', 'Prostate basal glandular cells': '0.472', 'Urothelial cells': '0.400', 'Keratinocyte (other)': '0.066', 'Keratinocyte (granular)': '-0.175', 'Hair cortex cells': '-0.062', 'Inner root sheath cells': '0.001', 'Outer root sheath cells': '0.141', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '-0.168', 'Adipocytes (Skin)': '-0.203', 'Mitotic cells (Skin)': '0.125', 'Parietal cells': '-0.625', 'Chief cells': '-0.550', 'Gastric mucous cells': '-0.265', 'Gastric enteroendocrine cells': '-0.370', 'Mitotic cells (Stomach)': '0.141', 'Parafollicular cells': '0.130', 'Thyroid glandular cells': '0.211', 'Mitotic cells (Thyroid)': '-0.107', 'Adrenal cortex cells': '0.479', 'Adrenal medulla cells': '-0.038', 'Mitotic cells (Adrenal gland)': '-0.230', 'Minor salivary glandular cells': '0.479', 'Minor salivary gland ductal cells': '0.178', 'Minor salivary gland basal cells': '0.373', 'Mitotic cells (Minor salivary gland)': '0.322', 'Adipocytes (Minor salivary gland)': '0.153', 'Somatotropes': '0.126', 'Lactotropes': '0.131', 'Gonadotropes': '0.010', 'Corticotropes': '0.056', 'Thyrotropes': '0.063', 'Undifferentiated cells (Pituitary gland)': '-0.033', 'Mitotic cells (Spleen)': '-0.231', 'Platelets': '-0.202', 'Erythrocytes': '-0.089', 'Hematopoietic stem cells': '-0.365', 'B-cells (Spleen)': '0.581', 'NK-cells (Spleen)': '0.287', 'Amygdala excitatory': '40.5', 'Cerebellar inhibitory': '52.2', 'Cge interneuron': '61.0', 'Deep-layer corticothalamic and 6b': '37.2', 'Deep-layer intratelencephalic': '36.3', 'Deep-layer near-projecting': '49.9', 'Eccentric medium spiny neuron': '57.5', 'Hippocampal ca1-3': '38.0', 'Hippocampal ca4': '32.4', 'Hippocampal dentate gyrus': '38.8', 'Lamp5-lhx6 and chandelier': '54.8', 'Lower rhombic lip': '37.0', 'Mammillary body': '47.7', 'Medium spiny neuron': '45.9', 'Mge interneuron': '52.3', 'Midbrain-derived inhibitory': '57.7', 'Miscellaneous': '41.8', 'Splatter': '44.5', 'Thalamic excitatory': '39.0', 'Upper rhombic lip': '68.5', 'Upper-layer intratelencephalic': '37.3', 'Astrocyte': '58.7', 'Bergmann glia': '48.5', 'Central nervous system macrophage': '63.1', 'Choroid plexus epithelial cell': '61.4', 'Committed oligodendrocyte precursor': '54.1', 'Ependymal cell': '68.1', 'Oligodendrocyte': '48.9', 'Oligodendrocyte precursor cell': '65.4', 'Endothelial cell': '53.4', 'Pericyte': '66.1', 'Vascular associated smooth muscle cell': '73.6', 'Fibroblast': '46.4', 'Leukocyte': '82.4', 'Basophil': '40.6', 'Eosinophil': '9.7', 'Neutrophil': '8.4', 'Classical monocyte': '112.6', 'Non-classical monocyte': '81.6', 'Intermediate monocyte': '95.5', 'T-reg': '133.1', 'GdT-cell': '23.0', 'MAIT T-cell': '159.8', 'Memory CD4 T-cell': '19.2', 'Naive CD4 T-cell': '205.6', 'Memory CD8 T-cell': '21.0', 'Naive CD8 T-cell': '230.5', 'Memory B-cell': '18.3', 'Naive B-cell': '163.6', 'Plasmacytoid DC': '114.2', 'Myeloid DC': '130.7', 'NK-cell': '138.6', 'Total PBMC': '99.1', 'Vd2 gdTCR': '145.4', 'Memory CD4 T-cell Th1\\/Th17': '190.3', 'Memory CD4 T-cell Th17': '214.8', 'Memory CD4 T-cell Th2': '226.9', 'Non-Vd2 gdTCR': '147.0', 'Memory CD4 T-cell Th1': '220.4', 'Memory CD4 T-cell TFH': '253.2', 'Terminal effector memory CD4 T-cell': '148.0', 'Central memory CD8 T-cell': '163.7', 'Effector memory CD8 T-cell': '127.8', 'Terminal effector memory CD8 T-cell': '154.2', 'Non-switched memory B-cell': '114.4', 'Plasmablast': '162.2', 'Switched memory B-cell': '142.4', 'Exhausted memory B-cell': '109.7', 'Progenitor cell': '127.3', 'Memory T-reg': '214.9', 'Naive CD4 T-cell activated': '425.0', 'Naive CD8 T-cell activated': '429.9', 'Naive T-reg': '218.0'}
|
2L33, 3P1X, 7RJM, 7RJQ
|
{'Adipose Tissue': 67.69812292358803, 'Adrenal Gland': 64.2834496124031, 'Bladder': 84.79857142857142, 'Blood': 43.43362217438106, 'Blood Vessel': 69.94496629213484, 'Brain': 42.52458932626798, 'Breast': 77.80714596949892, 'Cervix Uteri': 113.56368421052632, 'Colon': 73.13883183568677, 'Esophagus': 70.7884982698962, 'Fallopian Tube': 110.61444444444444, 'Heart': 30.12925551684088, 'Kidney': 40.78415730337078, 'Liver': 21.872769911504424, 'Lung': 93.62185121107268, 'Muscle': 46.768829389788294, 'Nerve': 87.94037156704361, 'Ovary': 135.8095, 'Pancreas': 30.47731707317073, 'Pituitary': 104.92826855123676, 'Prostate': 97.9274693877551, 'Salivary Gland': 63.61617283950617, 'Skin': 89.1936097291321, 'Small Intestine': 87.15251336898396, 'Spleen': 105.35058091286308, 'Stomach': 55.30916434540391, 'Testis': 92.0918836565097, 'Thyroid': 121.18623277182236, 'Uterus': 120.76352112676057, 'Vagina': 87.56455128205128}
|
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96.57, 95.92, 94.05, 94.13, 94.42, 93.21, 89.91, 89.69, 87.49, 87.69, 73.7, 63.14, 36.47, 38.44, 35.54, 34.16, 37.88, 36.05, 38.62, 38.61, 39.03, 43.16, 42.95, 39.95, 39.26, 40.99, 43.83, 40.57, 41.41, 40.01, 36.62, 41.56, 47.33, 44.27, 42.39, 44.21, 40.64, 42.54, 48.89, 40.73, 43.15, 52.65, 44.33, 46.88, 46.49, 51.99, 42.99, 48.9, 52.67, 48.76, 45.4, 40.17, 40.59, 45.97, 53.23, 50.23, 45.14, 49.81, 39.47, 40.91, 36.37, 37.96, 38.27, 38.92, 40.01, 37.85, 38.37, 35.64, 42.31, 36.87, 36.8, 37.26, 37.59, 39.18, 36.69, 37.88, 33.02, 36.58, 33.95, 37.08, 36.28, 37.77, 37.18, 34.9, 37.48, 36.65, 41.96, 37.61, 35.72, 33.78, 35.48, 34.71, 34.62, 34.39, 31.09, 33.53, 31.32, 34.21, 30.52, 33.86, 31.15, 35.98, 35.75, 34.08, 36.45, 33.44, 32.46, 32.98, 36.47, 34.13, 36.82, 32.4, 35.08, 35.82, 34.26, 34.9, 35.36, 36.44, 31.77, 37.93, 34.77, 34.74, 33.42, 33.06, 34.4, 34.04, 33.84, 33.29, 33.44, 32.36, 34.78, 31.78, 32.66, 30.82, 32.4, 31.95, 29.29, 37.22, 35.73, 30.42, 34.47, 32.32, 36.6, 33.93, 39.79, 38.85, 48.36, 50.19, 38.92, 41.6, 41.6, 39.65, 43.29, 40.48, 40.44, 40.53, 38.41, 39.08, 36.71, 38.18, 39.02, 39.52, 37.51, 39.13, 37.91, 35.82, 38.6, 36.3, 37.1, 35.73, 39.5, 36.68, 38.65, 36.07, 38.21, 37.95, 38.15, 35.99, 39.21, 33.0, 42.24, 37.72, 39.61, 44.29, 37.29, 37.77, 38.86, 39.19, 41.37, 47.16, 44.0, 38.96, 37.11, 39.0, 32.23, 37.87, 30.11, 33.9, 34.78, 32.12, 33.76, 31.99, 32.31, 30.67, 31.53, 31.73, 31.94, 31.94, 29.81, 31.07, 32.97, 31.66, 34.7, 35.04, 28.77, 30.19, 30.54, 31.56, 29.45, 32.77, 30.52, 32.44, 28.73, 30.48, 27.82, 31.55, 29.95, 35.82, 27.13, 36.14, 33.24, 29.81, 33.41, 29.56, 33.01, 33.25, 30.11, 35.02, 30.67, 36.91, 30.98, 39.36, 34.86, 34.19, 38.2, 32.26, 39.06, 33.51, 39.56, 38.43, 49.95, 37.97, 35.71, 40.28, 37.27, 34.52, 38.09, 35.26, 31.92, 35.13, 34.16, 38.66, 36.1, 39.68, 40.05, 39.74, 39.83, 41.58, 40.93, 41.7, 41.9, 38.83, 38.78, 38.03, 36.39, 34.76, 38.53, 34.33, 37.03, 37.63, 41.76, 50.91, 41.89, 41.78, 42.86, 41.64, 41.31, 40.74, 46.17, 39.51, 62.66, 52.58, 46.52, 38.41, 43.85, 39.08, 36.11, 44.51, 36.22, 42.17, 33.44, 34.21, 36.32, 34.95, 36.44, 37.16, 35.8, 41.49, 35.38, 45.72, 38.55, 44.83, 34.72, 40.78, 43.79]
|
[0.94, 0.82, 0.62, 0.6, 0.87, 0.58, 0.14, 0.51, 0.41, 0.04, 0.26, 0.33, 0.03, 0.0, 0.29, 0.33, 0.07, 0.01, 0.61, 0.48, 0.1, 0.25, 0.11, 0.43, 0.55, 0.77, 0.3, 0.08, 0.5, 0.21, 0.04, 0.25, 0.49, 0.01, 0.01, 0.25, 0.1, 0.0, 0.01, 0.41, 0.0, 0.0, 0.27, 0.24, 0.0, 0.06, 0.26, 0.33, 0.02, 0.08, 0.66, 0.45, 0.41, 0.54, 0.41, 0.61, 0.5, 0.74, 0.82, 0.76, 0.76, 0.76, 0.96, 0.9, 0.98, 0.95, 0.97, 0.9, 0.96, 0.95, 0.87, 0.8, 0.81, 0.86, 0.83, 0.78, 0.86, 0.5, 0.63, 0.69, 0.76, 0.58, 0.36, 0.44, 0.73, 0.59, 0.16, 0.2, 0.03, 0.32, 0.13, 0.01, 0.19, 0.12, 0.0, 0.11, 0.17, 0.1, 0.34, 0.09, 0.04, 0.01, 0.03, 0.1, 0.49, 0.65, 0.16, 0.3, 0.67, 0.02, 0.3, 0.01, 0.0, 0.0, 0.18, 0.03, 0.4, 0.8, 0.14, 0.01, 0.16, 0.24, 0.56, 0.18, 0.0, 0.35, 0.33, 0.0, 0.08, 0.68, 0.05, 0.0, 0.47, 0.66, 0.17, 0.04, 0.7, 0.76, 0.26, 0.21, 0.94, 0.48, 0.73, 0.22, 0.52, 0.3, 0.47, 0.45, 0.22, 0.4, 0.76, 0.44, 0.01, 0.01, 0.0, 0.23, 0.0, 0.34, 0.12, 0.61, 0.59, 0.99, 0.69, 0.44, 0.1, 0.19, 0.0, 0.22, 0.0, 0.25, 0.0, 0.0, 0.0, 0.43, 0.36, 0.04, 0.25, 0.57, 0.09, 0.35, 0.27, 0.4, 0.5, 0.65, 0.74, 0.72, 0.5, 0.91, 0.43, 0.89, 0.53, 0.93, 0.47, 0.52, 0.95, 0.31, 0.34, 0.03, 0.39, 0.34, 0.69, 0.35, 0.01, 0.14, 0.47, 0.04, 0.08, 0.15, 0.25, 0.06, 0.24, 0.13, 0.09, 0.53, 0.17, 0.01, 0.34, 0.24, 0.4, 0.0, 0.22, 0.56, 0.14, 0.55, 0.19, 0.0, 0.02, 0.11, 0.0, 0.02, 0.01, 0.01, 0.01, 0.08, 0.11, 0.05, 0.05, 0.63, 0.39, 0.33, 0.75, 0.38, 0.02, 0.37, 0.25, 0.01, 0.5, 0.34, 0.13, 0.08, 0.01, 0.05, 0.0, 0.03, 0.0, 0.08, 0.36, 0.04, 0.03, 0.41, 0.55, 0.22, 0.95, 0.46, 0.51, 0.04, 0.26, 0.05, 0.02, 0.14, 0.0, 0.02, 0.1, 0.32, 0.0, 0.0, 0.44, 0.22, 0.0, 0.18, 0.73, 0.15, 0.22, 0.0, 0.24, 0.62, 0.91, 0.41, 0.8, 0.15, 0.03, 0.55, 0.06, 0.41, 0.13, 0.33, 0.51, 0.71, 0.81, 0.39, 0.36, 0.11, 0.0, 0.51, 0.66, 0.07, 0.48, 0.79, 0.61, 0.29, 0.1, 0.47, 0.4, 0.0, 0.05, 0.57, 0.24, 0.0, 0.4, 0.48, 0.07, 0.21, 0.53, 0.19, 0.04, 0.67, 0.76, 0.39, 0.32, 0.03, 0.17, 0.64, 0.12, 0.01, 0.57, 0.25, 0.95, 0.64, 0.3, 0.67, 0.87, 0.88, 0.83, 0.8, 0.95, 0.87, 0.95, 0.89, 0.71, 0.83, 0.76, 0.91, 0.54, 0.65, 0.37, 0.19, 0.61, 0.12, 0.13, 0.63, 0.83, 0.16, 0.87, 0.39, 0.16, 0.77, 0.58, 0.88, 0.73, 0.63, 0.84, 0.23, 0.78, 0.91, 0.88, 0.91, 0.64, 0.73, 0.69, 0.85, 0.73, 0.69, 0.73, 0.82, 0.88, 0.88, 0.94, 0.9, 0.94, 0.95, 1.0, 0.87, 0.99, 0.85, 1.0, 0.97, 0.99, 0.96, 0.98, 0.82, 0.93, 0.76, 0.28, 0.54, 0.07, 0.26, 0.53, 0.42, 0.0, 0.56, 0.66, 0.53, 0.34, 0.74, 0.76, 0.24, 0.72, 0.21, 0.51, 0.44, 0.5, 0.35, 0.64, 0.5, 0.81, 0.49, 0.9, 0.78, 0.57, 0.2, 0.45, 0.13, 0.08, 0.02, 0.16, 0.04, 0.59, 0.03, 0.71, 0.81, 0.45, 0.75, 0.11, 0.47, 0.11, 0.42, 0.13, 0.64, 0.35, 0.44, 0.79, 0.32, 0.0, 0.32, 0.3, 0.39, 0.0, 0.0, 0.2, 0.48, 0.0, 0.05, 0.44, 0.57, 0.31, 0.71, 0.42, 0.92, 0.11, 0.78, 0.68, 0.73, 0.62, 0.84, 1.0, 1.0, 1.0, 0.96, 1.0, 0.96, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 0.99, 0.96, 0.99, 0.94, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.95, 0.99, 0.96, 1.0, 1.0, 0.8, 0.94, 0.94, 0.88, 1.0, 0.91, 0.94, 0.92, 0.8, 0.95, 0.59, 0.65, 0.8, 0.19, 0.55, 0.14, 0.69, 0.62, 0.53, 0.37, 0.38, 0.0, 0.27, 0.61, 0.06, 0.0, 0.46, 0.56, 0.51, 0.45, 0.84, 0.83, 0.24, 0.71, 0.17, 0.44, 0.43, 0.51, 0.33, 0.47, 0.55, 0.77, 0.48, 0.87, 0.96, 0.53, 0.37, 0.57, 0.08, 0.21, 0.09, 0.11, 0.01, 0.51, 0.01, 0.54, 0.73, 0.36, 0.58, 0.05, 0.51, 0.06, 0.47, 0.12, 0.44, 0.38, 0.42, 0.82, 0.15, 0.0, 0.31, 0.05, 0.46, 0.0, 0.0, 0.16, 0.28, 0.0, 0.06, 0.65, 0.67, 0.28, 0.25, 0.6, 0.58, 0.74, 0.88, 0.84, 0.97, 0.91, 0.93, 0.79, 0.92, 1.0, 0.97, 0.99, 1.0, 0.99, 0.97, 1.0, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.93, 0.99, 0.93, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.94, 0.99, 0.86, 1.0, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 1.0, 0.97, 1.0, 0.84, 0.98, 0.79, 0.9, 0.95, 0.96, 0.94, 0.95, 0.88, 0.96, 0.93, 0.94, 0.95, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.92, 1.0, 0.82, 1.0, 0.82, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.87, 0.92, 0.79, 0.81, 0.83, 0.7, 0.73, 0.8, 0.94, 0.99, 0.98, 1.0, 0.97, 1.0, 0.99, 0.91, 0.92, 0.55, 0.88, 0.81, 0.79, 0.79, 0.44, 0.67, 0.62, 0.71, 0.91, 0.88, 0.92, 0.84, 0.88, 0.9, 0.86, 0.97, 0.97, 0.93, 0.98, 0.85, 0.98, 0.89, 0.94, 1.0, 0.98, 1.0, 0.87, 1.0, 0.93, 1.0, 0.98, 0.94, 1.0, 0.99, 0.9, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.95, 0.94, 0.82, 0.86, 0.88, 0.9, 0.99, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 67.151365
| 0.619687
| 661
|
O43791
|
Q13158
|
30190126
|
UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
FADD
|
MDPFLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSGAMSPMSWNSDASTSEAS
|
Homo sapiens
| null |
Low tissue specificity
|
{'Ciliated cells': '8.5', 'Basal respiratory cells': '17.4', 'Club cells': '8.7', 'Ionocytes': '5.2', 'Mucus glandular cells': '6.4', 'Serous glandular cells': '5.4', 'Gastric mucus-secreting cells': '13.0', 'Proximal enterocytes': '23.6', 'Paneth cells': '11.7', 'Distal enterocytes': '23.8', 'Intestinal goblet cells': '16.0', 'Exocrine glandular cells': '-0.476', 'Basal prostatic cells': '8.5', 'Prostatic glandular cells': '10.8', 'Breast glandular cells': '0.165', 'Breast myoepithelial cells': '0.087', 'Glandular and luminal cells': '10.7', 'Secretory cells': '14.1', 'Basal keratinocytes': '9.2', 'Suprabasal keratinocytes': '10.5', 'Basal squamous epithelial cells': '8.4', 'Squamous epithelial cells': '14.7', 'Alveolar cells type 1': '0.023', 'Alveolar cells type 2': '0.281', 'Salivary duct cells': '5.8', 'Ductal cells': '0.430', 'Hepatocytes': '0.368', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.428', 'Distal tubular cells': '21.5', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.154', 'Sertoli cells': '0.451', 'Granulosa cells': '10.6', 'Enteroendocrine cells': '10.7', 'Pancreatic endocrine cells': '25.5', 'Leydig cells': '0.426', 'Excitatory neurons': '1.3', 'Inhibitory neurons': '1.5', 'Cone photoreceptor cells': '3.4', 'Rod photoreceptor cells': '3.1', 'Bipolar cells': '5.9', 'Horizontal cells': '5.0', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '1.3', 'Microglial cells': '2.7', 'Muller glia cells': '10.6', 'Schwann cells': '-0.001', 'Spermatogonia': '0.548', 'Spermatocytes': '0.347', 'Early spermatids': '-0.342', 'Late spermatids': '-0.351', 'Oocytes': '9.6', 'Cytotrophoblasts': '78.2', 'Syncytiotrophoblasts': '30.7', 'Extravillous trophoblasts': '38.4', 'Endothelial cells': '13.2', 'Lymphatic endothelial cells': '8.2', 'Cardiomyocytes': '0.548', 'Skeletal myocytes': '-0.067', 'Smooth muscle cells': '9.3', 'Adipocytes': '8.4', 'Melanocytes': '0.172', 'Fibroblasts': '12.3', 'Peritubular cells': '0.250', 'Endometrial stromal cells': '11.8', 'Ovarian stromal cells': '9.8', 'Undifferentiated cells': '18.5', 'T-cells': '12.9', 'B-cells': '11.0', 'Plasma cells': '12.1', 'Nk-cells': '14.1', 'Granulocytes': '6.0', 'Monocytes': '4.1', 'Macrophages': '8.6', 'Hofbauer cells': '23.9', 'Kupffer cells': '10.0', 'Dendritic cells': '6.4', 'Langerhans cells': '0.287', 'Erythroid cells': '-0.198', 'Adipocytes (Subcutaneous)': '0.109', 'Adipocytes (Visceral)': '0.200', 'Breast glandular cells (progenitors)': '0.144', 'Adipocytes (Breast)': '-0.026', 'Colon enterocytes': '0.161', 'Colon enteroendocrine cells': '-0.072', 'Enteric glia cells': '-0.569', 'Mitotic cells (Colon)': '0.102', 'Mitotic cells (Heart)': '0.486', 'Podocytes': '-0.155', 'Ascending Loop of Henle cells': '0.278', 'Intercalated cells': '-0.137', 'Cholangiocyte': '0.296', 'NK-cells (Liver)': '-0.291', 'Respiratory ciliated cells': '-0.103', 'Mitotic cells (Lung)': '0.190', 'NK-cells (Lung)': '-0.235', 'B-cells (Lung)': '-0.267', 'Alpha cells': '0.305', 'Beta cells': '0.136', 'Prostate glandular cells': '-0.048', 'Prostate basal glandular cells': '0.247', 'Urothelial cells': '0.081', 'Keratinocyte (other)': '0.385', 'Keratinocyte (granular)': '0.084', 'Hair cortex cells': '-0.012', 'Inner root sheath cells': '-0.055', 'Outer root sheath cells': '0.036', 'Sebaceous gland cells': '0.034', 'Eccrine sweat gland cells': '-0.138', 'Adipocytes (Skin)': '-0.170', 'Mitotic cells (Skin)': '0.312', 'Parietal cells': '-0.288', 'Chief cells': '-0.272', 'Gastric mucous cells': '0.044', 'Gastric enteroendocrine cells': '-0.196', 'Mitotic cells (Stomach)': '0.329', 'Parafollicular cells': '0.022', 'Thyroid glandular cells': '0.184', 'Mitotic cells (Thyroid)': '0.016', 'Adrenal cortex cells': '0.611', 'Adrenal medulla cells': '0.024', 'Mitotic cells (Adrenal gland)': '0.430', 'Minor salivary glandular cells': '0.360', 'Minor salivary gland ductal cells': '-0.105', 'Minor salivary gland basal cells': '0.407', 'Mitotic cells (Minor salivary gland)': '0.501', 'Adipocytes (Minor salivary gland)': '0.125', 'Somatotropes': '-0.008', 'Lactotropes': '-0.094', 'Gonadotropes': '-0.035', 'Corticotropes': '-0.133', 'Thyrotropes': '-0.043', 'Undifferentiated cells (Pituitary gland)': '0.239', 'Mitotic cells (Spleen)': '0.064', 'Platelets': '0.104', 'Erythrocytes': '-0.204', 'Hematopoietic stem cells': '0.025', 'B-cells (Spleen)': '0.049', 'NK-cells (Spleen)': '-0.099', 'Amygdala excitatory': '2.0', 'Cerebellar inhibitory': '2.6', 'Cge interneuron': '2.9', 'Deep-layer corticothalamic and 6b': '2.3', 'Deep-layer intratelencephalic': '2.1', 'Deep-layer near-projecting': '2.7', 'Eccentric medium spiny neuron': '2.8', 'Hippocampal ca1-3': '2.8', 'Hippocampal ca4': '3.7', 'Hippocampal dentate gyrus': '2.0', 'Lamp5-lhx6 and chandelier': '3.0', 'Lower rhombic lip': '2.5', 'Mammillary body': '2.0', 'Medium spiny neuron': '2.4', 'Mge interneuron': '2.0', 'Midbrain-derived inhibitory': '2.7', 'Miscellaneous': '2.3', 'Splatter': '3.0', 'Thalamic excitatory': '3.3', 'Upper rhombic lip': '3.0', 'Upper-layer intratelencephalic': '2.0', 'Astrocyte': '2.2', 'Bergmann glia': '1.9', 'Central nervous system macrophage': '3.1', 'Choroid plexus epithelial cell': '3.7', 'Committed oligodendrocyte precursor': '4.0', 'Ependymal cell': '2.8', 'Oligodendrocyte': '3.8', 'Oligodendrocyte precursor cell': '3.3', 'Endothelial cell': '10.4', 'Pericyte': '6.9', 'Vascular associated smooth muscle cell': '5.6', 'Fibroblast': '4.2', 'Leukocyte': '6.8', 'Basophil': '23.4', 'Eosinophil': '28.3', 'Neutrophil': '99.4', 'Classical monocyte': '0.6', 'Non-classical monocyte': '0.5', 'Intermediate monocyte': '31.6', 'T-reg': '32.8', 'GdT-cell': '41.7', 'MAIT T-cell': '23.9', 'Memory CD4 T-cell': '44.2', 'Naive CD4 T-cell': '1.4', 'Memory CD8 T-cell': '48.9', 'Naive CD8 T-cell': '1.5', 'Memory B-cell': '38.8', 'Naive B-cell': '0.6', 'Plasmacytoid DC': '22.6', 'Myeloid DC': '37.0', 'NK-cell': '1.4', 'Total PBMC': '35.7', 'Vd2 gdTCR': '21.6', 'Memory CD4 T-cell Th1\\/Th17': '1.1', 'Memory CD4 T-cell Th17': '1.4', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '26.6', 'Memory CD4 T-cell Th1': '1.7', 'Memory CD4 T-cell TFH': '2.3', 'Terminal effector memory CD4 T-cell': '32.5', 'Central memory CD8 T-cell': '16.7', 'Effector memory CD8 T-cell': '23.2', 'Terminal effector memory CD8 T-cell': '23.6', 'Non-switched memory B-cell': '21.5', 'Plasmablast': '49.4', 'Switched memory B-cell': '27.9', 'Exhausted memory B-cell': '28.5', 'Progenitor cell': '30.7', 'Memory T-reg': '2.3', 'Naive CD4 T-cell activated': '2.8', 'Naive CD8 T-cell activated': '3.6', 'Naive T-reg': '1.6'}
|
1A1W, 1A1Z, 1E3Y, 1E41, 2GF5, 3EZQ, 3OQ9, 6ACI, 7LXC, 8YBX, 8YD7, 8YD8
|
{'Adipose Tissue': 10.058419435215946, 'Adrenal Gland': 12.371111240310078, 'Bladder': 12.396714285714287, 'Blood': 21.031252099031217, 'Blood Vessel': 10.242140074906366, 'Brain': 3.986157112036336, 'Breast': 11.350082788671024, 'Cervix Uteri': 10.867, 'Colon': 10.213613350449297, 'Esophagus': 11.151711903114188, 'Fallopian Tube': 11.94288888888889, 'Heart': 3.2859193960511033, 'Kidney': 7.26761797752809, 'Liver': 4.896703982300885, 'Lung': 9.703112456747403, 'Muscle': 4.276478704856787, 'Nerve': 9.657298869143782, 'Ovary': 9.313223888888889, 'Pancreas': 3.3681155487804877, 'Pituitary': 6.820395759717314, 'Prostate': 8.127097959183674, 'Salivary Gland': 10.380487654320987, 'Skin': 16.24984577114428, 'Small Intestine': 11.436903743315508, 'Spleen': 11.766775933609958, 'Stomach': 7.748461281337048, 'Testis': 8.281659279778394, 'Thyroid': 9.694030627871363, 'Uterus': 14.49844366197183, 'Vagina': 10.728397435897437}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[48.93, 64.65, 71.46, 70.54, 71.18, 78.1, 76.47, 77.65, 80.18, 80.76, 78.91, 78.88, 80.84, 80.14, 77.55, 78.29, 78.58, 80.14, 81.4, 78.56, 79.64, 80.8, 77.38, 76.36, 76.74, 73.47, 69.11, 66.51, 66.13, 62.65, 64.87, 64.75, 65.88, 67.35, 65.52, 67.48, 70.29, 71.73, 68.6, 68.59, 73.44, 72.73, 76.81, 78.77, 76.94, 74.23, 73.1, 72.35, 72.48, 71.06, 70.19, 64.79, 59.76, 60.78, 62.51, 61.55, 59.14, 54.64, 58.88, 66.99, 65.01, 66.33, 72.05, 72.98, 75.38, 73.0, 73.82, 77.01, 75.62, 71.59, 66.63, 67.02, 71.43, 75.82, 72.77, 71.78, 73.93, 72.66, 71.74, 69.64, 72.4, 69.45, 66.08, 63.72, 61.59, 57.06, 51.72, 47.19, 46.63, 47.65, 52.13, 52.02, 57.87, 61.75, 62.48, 67.55, 70.0, 67.4, 72.59, 76.07, 75.3, 74.47, 78.83, 78.15, 73.51, 74.83, 72.58, 70.55, 70.56, 73.43, 75.9, 82.3, 82.43, 81.88, 82.33, 83.6, 84.31, 82.72, 80.23, 79.35, 80.33, 82.51, 83.82, 84.75, 80.72, 83.64, 83.47, 82.88, 81.21, 80.5, 81.37, 76.49, 73.91, 73.08, 69.71, 74.57, 78.33, 74.97, 75.71, 80.98, 81.16, 77.41, 78.33, 81.67, 80.02, 73.98, 78.84, 81.46, 78.98, 74.56, 74.25, 70.79, 64.34, 61.23, 64.19, 69.16, 75.5, 76.0, 80.47, 79.87, 81.17, 82.98, 84.56, 84.08, 83.03, 84.99, 84.15, 78.55, 75.81, 75.53, 78.99, 80.37, 79.11, 82.43, 85.04, 82.48, 80.82, 82.42, 82.11, 75.66, 77.12, 79.38, 76.9, 67.97, 71.18, 70.66, 66.23, 61.93, 59.41, 58.4, 52.66, 47.55, 39.59, 43.24, 41.16, 43.26, 45.21, 49.89, 46.87, 45.68, 48.28, 47.46, 54.76, 49.01, 60.37, 53.66, 61.86, 52.66]
|
[0.93, 0.59, 0.55, 0.04, 0.43, 0.56, 0.12, 0.04, 0.58, 0.42, 0.03, 0.11, 0.72, 0.3, 0.09, 0.36, 0.69, 0.57, 0.18, 0.16, 0.47, 0.51, 0.01, 0.24, 0.65, 0.49, 0.03, 0.4, 0.9, 0.63, 0.02, 0.55, 0.64, 0.81, 0.41, 0.12, 0.62, 0.74, 0.02, 0.76, 0.41, 0.01, 0.35, 0.36, 0.03, 0.01, 0.39, 0.17, 0.03, 0.27, 0.77, 0.29, 0.33, 0.22, 0.01, 0.3, 0.47, 0.78, 0.46, 0.02, 0.51, 0.22, 0.0, 0.29, 0.53, 0.1, 0.02, 0.37, 0.48, 0.11, 0.76, 0.27, 0.59, 0.75, 0.04, 0.11, 0.7, 0.58, 0.03, 0.34, 0.6, 0.26, 0.14, 0.56, 0.61, 0.32, 0.39, 0.76, 0.79, 0.34, 0.61, 0.56, 0.45, 0.42, 0.44, 0.16, 0.07, 0.2, 0.23, 0.02, 0.14, 0.49, 0.18, 0.0, 0.05, 0.81, 0.53, 0.02, 0.3, 0.79, 0.39, 0.01, 0.44, 0.64, 0.0, 0.0, 0.5, 0.53, 0.05, 0.73, 0.07, 0.47, 0.45, 0.71, 0.44, 0.01, 0.48, 0.37, 0.03, 0.29, 0.8, 0.77, 0.32, 0.69, 0.97, 0.49, 0.34, 0.43, 0.33, 0.08, 0.01, 0.44, 0.23, 0.0, 0.01, 0.3, 0.11, 0.01, 0.26, 0.46, 0.61, 0.21, 0.71, 0.96, 0.51, 0.13, 0.41, 0.07, 0.66, 0.49, 0.0, 0.06, 0.37, 0.05, 0.0, 0.48, 0.55, 0.15, 0.8, 0.13, 0.5, 0.82, 0.08, 0.01, 0.44, 0.4, 0.02, 0.29, 0.62, 0.28, 0.28, 0.6, 0.41, 0.32, 0.49, 0.66, 0.67, 0.56, 0.8, 0.61, 0.61, 0.73, 0.8, 0.78, 0.9, 0.85, 0.77, 0.85, 0.87, 0.84, 0.87, 0.86, 0.86, 0.9, 1.0, 1.0, 1.0, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 71.042356
| 0.411394
| 2,708
|
O43791
|
Q14444
|
nan, 31771591
|
degron_data, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
CAPRIN1
|
MPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSEEELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERVFQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRSNQPYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPNSGYTQSQFSAPRDYSGYQRDGYQQNFKRGSGQSGPRGAPRGRGGPPRPNRGMPQMNTQQVN
|
Homo sapiens
|
Cytoplasm, Cytoplasmic ribonucleoprotein granule, Cytoplasm, cytosol, Cell projection, dendrite, Cell projection, lamellipodium, Cytoplasm, cytosol
|
Low tissue specificity
|
{'Ciliated cells': '69.2', 'Basal respiratory cells': '51.9', 'Club cells': '55.5', 'Ionocytes': '46.4', 'Mucus glandular cells': '63.9', 'Serous glandular cells': '55.8', 'Gastric mucus-secreting cells': '61.9', 'Proximal enterocytes': '43.0', 'Paneth cells': '52.4', 'Distal enterocytes': '55.5', 'Intestinal goblet cells': '49.2', 'Exocrine glandular cells': '-0.654', 'Basal prostatic cells': '69.2', 'Prostatic glandular cells': '74.2', 'Breast glandular cells': '0.366', 'Breast myoepithelial cells': '0.564', 'Glandular and luminal cells': '147.3', 'Secretory cells': '66.7', 'Basal keratinocytes': '83.5', 'Suprabasal keratinocytes': '76.9', 'Basal squamous epithelial cells': '77.1', 'Squamous epithelial cells': '95.3', 'Alveolar cells type 1': '0.064', 'Alveolar cells type 2': '-0.188', 'Salivary duct cells': '58.3', 'Ductal cells': '0.556', 'Hepatocytes': '0.565', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.197', 'Distal tubular cells': '18.4', 'Collecting duct cells': '60.3', 'Mesothelial cells': '0.307', 'Sertoli cells': '-0.105', 'Granulosa cells': '47.5', 'Enteroendocrine cells': '56.8', 'Pancreatic endocrine cells': '56.0', 'Leydig cells': '-0.132', 'Excitatory neurons': '36.1', 'Inhibitory neurons': '37.2', 'Cone photoreceptor cells': '45.9', 'Rod photoreceptor cells': '30.3', 'Bipolar cells': '34.3', 'Horizontal cells': '26.4', 'Astrocytes': '35.9', 'Oligodendrocyte precursor cells': '41.5', 'Oligodendrocytes': '49.5', 'Microglial cells': '35.8', 'Muller glia cells': '38.9', 'Schwann cells': '0.122', 'Spermatogonia': '0.301', 'Spermatocytes': '0.642', 'Early spermatids': '0.688', 'Late spermatids': '0.243', 'Oocytes': '55.9', 'Cytotrophoblasts': '49.6', 'Syncytiotrophoblasts': '51.4', 'Extravillous trophoblasts': '62.5', 'Endothelial cells': '58.7', 'Lymphatic endothelial cells': '72.4', 'Cardiomyocytes': '0.634', 'Skeletal myocytes': '-0.223', 'Smooth muscle cells': '51.5', 'Adipocytes': '44.9', 'Melanocytes': '0.340', 'Fibroblasts': '64.3', 'Peritubular cells': '-0.106', 'Endometrial stromal cells': '120.7', 'Ovarian stromal cells': '37.3', 'Undifferentiated cells': '75.9', 'T-cells': '51.8', 'B-cells': '50.6', 'Plasma cells': '83.6', 'Nk-cells': '42.0', 'Granulocytes': '56.1', 'Monocytes': '70.5', 'Macrophages': '69.3', 'Hofbauer cells': '60.0', 'Kupffer cells': '62.5', 'Dendritic cells': '77.3', 'Langerhans cells': '0.289', 'Erythroid cells': '-0.025', 'Adipocytes (Subcutaneous)': '-0.196', 'Adipocytes (Visceral)': '-0.292', 'Breast glandular cells (progenitors)': '0.294', 'Adipocytes (Breast)': '-0.489', 'Colon enterocytes': '-0.161', 'Colon enteroendocrine cells': '0.365', 'Enteric glia cells': '0.220', 'Mitotic cells (Colon)': '0.055', 'Mitotic cells (Heart)': '0.524', 'Podocytes': '0.055', 'Ascending Loop of Henle cells': '0.451', 'Intercalated cells': '0.111', 'Cholangiocyte': '0.395', 'NK-cells (Liver)': '-0.305', 'Respiratory ciliated cells': '0.031', 'Mitotic cells (Lung)': '0.103', 'NK-cells (Lung)': '0.128', 'B-cells (Lung)': '-0.017', 'Alpha cells': '0.359', 'Beta cells': '0.167', 'Prostate glandular cells': '-0.115', 'Prostate basal glandular cells': '0.164', 'Urothelial cells': '0.192', 'Keratinocyte (other)': '0.402', 'Keratinocyte (granular)': '-0.182', 'Hair cortex cells': '0.008', 'Inner root sheath cells': '0.127', 'Outer root sheath cells': '0.237', 'Sebaceous gland cells': '0.063', 'Eccrine sweat gland cells': '-0.021', 'Adipocytes (Skin)': '-0.216', 'Mitotic cells (Skin)': '0.483', 'Parietal cells': '-0.560', 'Chief cells': '-0.402', 'Gastric mucous cells': '-0.318', 'Gastric enteroendocrine cells': '-0.310', 'Mitotic cells (Stomach)': '0.128', 'Parafollicular cells': '0.142', 'Thyroid glandular cells': '0.572', 'Mitotic cells (Thyroid)': '0.093', 'Adrenal cortex cells': '0.555', 'Adrenal medulla cells': '0.012', 'Mitotic cells (Adrenal gland)': '0.393', 'Minor salivary glandular cells': '0.514', 'Minor salivary gland ductal cells': '-0.014', 'Minor salivary gland basal cells': '0.496', 'Mitotic cells (Minor salivary gland)': '0.575', 'Adipocytes (Minor salivary gland)': '0.194', 'Somatotropes': '-0.034', 'Lactotropes': '-0.077', 'Gonadotropes': '0.016', 'Corticotropes': '-0.182', 'Thyrotropes': '0.166', 'Undifferentiated cells (Pituitary gland)': '0.379', 'Mitotic cells (Spleen)': '-0.023', 'Platelets': '-0.177', 'Erythrocytes': '-0.097', 'Hematopoietic stem cells': '-0.226', 'B-cells (Spleen)': '0.207', 'NK-cells (Spleen)': '0.243', 'Amygdala excitatory': '56.4', 'Cerebellar inhibitory': '56.5', 'Cge interneuron': '62.6', 'Deep-layer corticothalamic and 6b': '51.0', 'Deep-layer intratelencephalic': '49.6', 'Deep-layer near-projecting': '47.4', 'Eccentric medium spiny neuron': '68.1', 'Hippocampal ca1-3': '62.1', 'Hippocampal ca4': '60.7', 'Hippocampal dentate gyrus': '63.1', 'Lamp5-lhx6 and chandelier': '65.5', 'Lower rhombic lip': '54.6', 'Mammillary body': '78.0', 'Medium spiny neuron': '69.2', 'Mge interneuron': '57.1', 'Midbrain-derived inhibitory': '110.4', 'Miscellaneous': '58.5', 'Splatter': '59.8', 'Thalamic excitatory': '60.9', 'Upper rhombic lip': '68.7', 'Upper-layer intratelencephalic': '46.7', 'Astrocyte': '64.0', 'Bergmann glia': '65.6', 'Central nervous system macrophage': '90.5', 'Choroid plexus epithelial cell': '72.7', 'Committed oligodendrocyte precursor': '77.9', 'Ependymal cell': '89.1', 'Oligodendrocyte': '74.0', 'Oligodendrocyte precursor cell': '67.7', 'Endothelial cell': '87.0', 'Pericyte': '82.9', 'Vascular associated smooth muscle cell': '55.8', 'Fibroblast': '72.6', 'Leukocyte': '90.2', 'Basophil': '93.0', 'Eosinophil': '13.9', 'Neutrophil': '90.7', 'Classical monocyte': '95.0', 'Non-classical monocyte': '116.2', 'Intermediate monocyte': '179.6', 'T-reg': '103.6', 'GdT-cell': '18.8', 'MAIT T-cell': '95.5', 'Memory CD4 T-cell': '21.0', 'Naive CD4 T-cell': '104.7', 'Memory CD8 T-cell': '23.2', 'Naive CD8 T-cell': '91.2', 'Memory B-cell': '19.5', 'Naive B-cell': '81.6', 'Plasmacytoid DC': '219.8', 'Myeloid DC': '130.7', 'NK-cell': '83.1', 'Total PBMC': '101.6', 'Vd2 gdTCR': '82.6', 'Memory CD4 T-cell Th1\\/Th17': '104.0', 'Memory CD4 T-cell Th17': '96.3', 'Memory CD4 T-cell Th2': '98.1', 'Non-Vd2 gdTCR': '89.6', 'Memory CD4 T-cell Th1': '83.4', 'Memory CD4 T-cell TFH': '83.6', 'Terminal effector memory CD4 T-cell': '95.8', 'Central memory CD8 T-cell': '104.0', 'Effector memory CD8 T-cell': '102.2', 'Terminal effector memory CD8 T-cell': '94.6', 'Non-switched memory B-cell': '91.7', 'Plasmablast': '173.1', 'Switched memory B-cell': '85.0', 'Exhausted memory B-cell': '83.8', 'Progenitor cell': '189.6', 'Naive CD4 T-cell activated': '346.1', 'Naive CD8 T-cell activated': '290.9', 'Memory T-reg': '81.1', 'Naive T-reg': '101.6'}
|
4WBE, 4WBP, 6TA7, 7XHG, 8TH7
|
{'Adipose Tissue': 52.01695182724253, 'Adrenal Gland': 35.50989534883721, 'Bladder': 52.558571428571426, 'Blood': 33.941067814854684, 'Blood Vessel': 54.87761797752809, 'Brain': 31.003763058289177, 'Breast': 53.248431372549014, 'Cervix Uteri': 65.72684210526316, 'Colon': 40.28363286264442, 'Esophagus': 40.057204152249135, 'Fallopian Tube': 56.35888888888889, 'Heart': 19.265658536585367, 'Kidney': 27.93391011235955, 'Liver': 13.70067256637168, 'Lung': 53.37977508650519, 'Muscle': 22.411987546699876, 'Nerve': 60.14050080775444, 'Ovary': 63.576277777777776, 'Pancreas': 19.193881097560975, 'Pituitary': 42.80593639575971, 'Prostate': 44.57828571428571, 'Salivary Gland': 41.178703703703704, 'Skin': 63.921531232725265, 'Small Intestine': 37.08802139037433, 'Spleen': 35.35622406639004, 'Stomach': 32.02710306406685, 'Testis': 94.7707756232687, 'Thyroid': 50.81205206738131, 'Uterus': 61.09126760563379, 'Vagina': 54.87282051282051}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
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|
[43.88, 64.16, 57.15, 54.24, 52.72, 43.59, 54.16, 46.73, 42.77, 50.47, 42.31, 52.09, 44.12, 51.91, 48.37, 54.75, 59.53, 59.47, 72.2, 57.21, 42.85, 48.06, 45.35, 44.59, 41.31, 41.57, 40.49, 39.79, 37.46, 35.6, 35.56, 35.87, 34.55, 39.0, 36.11, 35.68, 36.51, 40.42, 36.01, 36.53, 42.66, 41.35, 49.29, 51.39, 59.09, 66.7, 75.8, 78.6, 85.37, 83.79, 89.82, 91.76, 93.38, 93.74, 93.83, 95.99, 95.85, 96.17, 96.65, 97.68, 97.4, 97.55, 97.65, 97.58, 98.12, 97.75, 97.81, 98.15, 98.05, 97.97, 97.46, 97.66, 97.53, 97.06, 97.54, 97.33, 96.85, 96.99, 94.6, 96.17, 95.31, 92.46, 93.97, 95.78, 92.44, 93.86, 91.05, 93.55, 94.48, 95.32, 95.84, 95.87, 94.47, 95.8, 96.33, 96.07, 95.74, 95.8, 96.91, 97.62, 97.05, 98.15, 97.59, 97.83, 97.86, 98.01, 97.85, 98.08, 97.66, 98.1, 97.83, 97.28, 97.38, 97.79, 97.51, 97.22, 96.3, 96.9, 96.11, 94.92, 95.69, 96.04, 94.07, 93.06, 95.97, 94.9, 92.77, 94.55, 96.22, 94.22, 94.63, 96.48, 96.82, 95.56, 96.93, 97.21, 96.47, 97.25, 97.61, 97.66, 96.95, 97.17, 97.75, 97.71, 97.76, 98.41, 98.43, 98.19, 98.64, 98.45, 98.0, 98.39, 97.82, 97.59, 97.39, 98.09, 97.2, 96.34, 96.67, 95.46, 96.49, 96.23, 94.8, 95.29, 96.06, 94.76, 93.92, 94.7, 94.62, 90.81, 83.07, 76.38, 73.51, 77.62, 84.33, 89.94, 92.68, 96.44, 95.83, 96.05, 97.23, 97.59, 97.63, 97.89, 98.24, 98.36, 98.18, 98.36, 98.58, 98.38, 97.85, 98.11, 98.28, 97.74, 97.16, 96.38, 97.07, 96.45, 96.21, 96.85, 96.31, 97.17, 96.08, 95.02, 97.2, 95.05, 97.62, 97.53, 96.12, 98.21, 98.13, 98.26, 98.67, 98.62, 98.34, 98.58, 98.69, 98.14, 97.71, 98.19, 98.2, 98.21, 98.36, 98.23, 98.35, 96.95, 96.79, 97.63, 98.48, 98.76, 98.6, 98.48, 98.6, 98.46, 98.27, 98.16, 97.83, 97.55, 96.15, 96.21, 95.67, 94.43, 93.11, 91.12, 93.24, 93.85, 93.11, 84.25, 66.69, 63.45, 46.03, 45.7, 31.5, 34.77, 32.56, 32.89, 32.5, 31.56, 37.99, 33.45, 35.43, 39.11, 37.35, 40.72, 40.25, 43.04, 41.04, 41.87, 44.93, 40.63, 40.87, 41.39, 42.11, 40.11, 42.36, 42.9, 40.57, 45.32, 41.21, 41.98, 39.97, 41.26, 38.35, 29.7, 39.87, 35.33, 35.53, 37.18, 38.92, 40.98, 49.2, 46.77, 55.66, 49.27, 49.31, 44.82, 47.73, 45.36, 37.78, 43.44, 43.97, 39.25, 44.68, 37.69, 36.75, 34.5, 38.31, 35.78, 36.26, 39.19, 37.83, 33.92, 34.23, 36.61, 35.98, 37.5, 39.31, 42.32, 42.06, 37.47, 40.53, 43.87, 41.14, 40.74, 36.08, 37.87, 40.42, 39.44, 41.3, 38.01, 36.16, 36.87, 36.17, 40.34, 40.76, 38.04, 40.8, 40.82, 38.31, 37.92, 36.37, 38.24, 34.31, 32.01, 34.12, 38.63, 35.82, 43.99, 43.41, 51.93, 62.99, 80.82, 83.79, 83.88, 79.53, 84.53, 85.56, 85.59, 86.97, 86.13, 87.55, 86.7, 80.19, 81.03, 78.69, 71.66, 67.98, 59.77, 61.75, 45.6, 51.44, 58.63, 62.08, 53.11, 52.61, 49.06, 47.45, 47.94, 45.35, 46.37, 40.03, 38.02, 45.76, 47.81, 41.51, 36.54, 49.27, 46.73, 52.93, 47.38, 50.16, 46.26, 44.47, 49.53, 44.82, 43.59, 43.12, 34.54, 42.34, 37.25, 48.02, 39.83, 43.82, 40.89, 37.39, 43.01, 37.46, 36.22, 41.58, 37.44, 38.42, 35.24, 39.13, 32.75, 40.72, 33.24, 36.47, 41.07, 35.83, 40.46, 40.81, 37.82, 41.25, 38.62, 44.66, 43.9, 47.03, 43.96, 41.73, 54.98, 35.52, 42.03, 35.59, 44.32, 39.88, 30.85, 40.07, 40.47, 37.39, 42.99, 40.41, 38.5, 41.7, 36.58, 41.98, 34.32, 52.43, 38.46, 31.1, 33.31, 37.6, 36.91, 40.1, 40.31, 39.67, 35.86, 38.19, 34.37, 39.0, 38.11, 42.03, 34.58, 42.88, 50.54, 42.66, 37.77, 43.96, 36.26, 37.26, 34.48, 51.86, 31.29, 43.91, 36.64, 34.73, 40.56, 34.15, 36.58, 38.4, 38.64, 40.0, 43.05, 37.86, 45.82, 40.05, 35.52, 40.93, 42.87, 34.29, 43.45, 40.59, 39.12, 39.17, 38.9, 36.28, 37.27, 38.9, 37.61, 42.16, 39.5, 39.23, 37.19, 39.49, 39.56, 40.3, 49.88, 43.37, 49.43, 44.04, 44.95, 48.72, 45.78, 47.24, 48.16, 43.54, 38.03, 42.86, 43.96, 44.16, 42.97, 40.1, 46.87, 39.97, 41.99, 48.12, 44.78, 51.38, 47.52, 45.39, 44.27, 40.5, 45.75, 33.76, 36.37, 40.16, 37.95, 36.99, 38.08, 41.4, 35.94, 37.43, 33.75, 38.87, 36.21, 34.56, 35.19, 39.69, 39.45, 34.93, 38.42, 35.94, 39.14, 36.83, 37.35, 37.98, 34.33, 37.73, 32.79, 39.79, 32.17, 34.68, 37.5, 35.86, 35.2, 36.69, 36.37, 38.02, 36.63, 40.22, 35.9, 39.71, 37.66, 35.41, 37.69, 40.78, 33.3, 48.64, 41.28, 36.67, 38.05, 39.48, 36.92, 35.72, 35.89, 45.34, 37.16, 41.77, 44.79, 38.59, 46.67, 48.12, 44.02, 43.63, 36.59, 38.04, 43.85, 37.51, 43.39, 34.66, 40.63, 37.07, 34.4, 45.18, 35.62, 34.02, 36.54, 35.64, 34.85, 36.72, 40.79, 39.31, 35.05, 35.79, 38.16, 39.39, 44.05, 37.56, 43.94, 34.67, 43.82, 38.55, 36.24, 33.91, 32.88, 31.25, 36.64, 32.3, 42.76, 33.81, 34.08, 35.97, 33.64, 39.69, 36.59, 37.17, 35.48, 43.02, 42.43, 38.27, 47.21, 45.94, 38.23, 39.63, 39.39, 34.4, 40.96, 40.94, 36.11, 41.83, 35.86, 38.33, 38.83, 34.71, 41.58, 34.46, 42.05, 31.72, 35.47, 44.08, 40.92, 34.47, 40.16, 36.14, 33.57, 40.93, 33.02, 35.33, 39.4, 35.1, 37.38, 37.23, 44.94, 33.83, 40.75, 46.59, 38.63, 41.0, 40.54, 41.62, 42.45, 41.34, 38.72, 44.21, 38.84, 38.51, 40.24, 43.0, 42.82, 37.51, 43.03, 39.12, 50.66, 59.12, 48.22, 55.88, 56.88, 41.21, 44.4, 41.23, 48.2, 57.51, 46.82, 57.28, 45.43, 52.47, 52.99, 51.12, 57.33, 52.12]
|
[1.0, 0.99, 0.99, 0.99, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.98, 0.97, 0.99, 1.0, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.94, 0.96, 0.75, 0.84, 0.85, 0.84, 0.88, 0.88, 0.88, 0.82, 0.72, 0.9, 0.68, 0.68, 0.53, 0.69, 0.49, 0.49, 0.13, 0.58, 0.65, 0.49, 0.26, 0.47, 0.4, 0.08, 0.55, 0.6, 0.38, 0.17, 0.41, 0.66, 0.09, 0.28, 0.63, 0.56, 0.05, 0.51, 0.48, 0.08, 0.46, 0.67, 0.58, 0.26, 0.33, 0.62, 0.09, 0.32, 0.5, 0.23, 0.32, 0.53, 0.31, 0.44, 0.76, 0.63, 0.77, 0.52, 0.97, 0.11, 0.66, 0.64, 0.76, 0.23, 0.4, 0.43, 0.24, 0.16, 0.74, 0.59, 0.21, 0.63, 0.58, 0.11, 0.14, 0.48, 0.35, 0.07, 0.57, 0.63, 0.08, 0.42, 0.48, 0.34, 0.24, 0.54, 0.5, 0.23, 0.41, 0.46, 0.47, 0.16, 0.55, 0.45, 0.22, 0.5, 0.5, 0.56, 0.34, 0.74, 0.71, 0.46, 0.49, 0.5, 0.71, 0.32, 0.38, 0.45, 0.6, 0.56, 0.35, 0.41, 0.42, 0.61, 0.66, 0.57, 0.4, 0.57, 0.59, 0.29, 0.17, 0.63, 0.34, 0.04, 0.47, 0.52, 0.07, 0.04, 0.61, 0.36, 0.04, 0.75, 0.46, 0.68, 0.47, 0.11, 0.15, 0.43, 0.29, 0.0, 0.34, 0.62, 0.26, 0.58, 0.95, 0.68, 0.73, 0.59, 0.11, 0.02, 0.35, 0.49, 0.7, 0.2, 0.0, 0.41, 0.2, 0.03, 0.27, 0.48, 0.02, 0.34, 0.58, 0.34, 0.09, 0.51, 0.23, 0.9, 0.54, 0.45, 0.89, 0.8, 0.41, 0.61, 0.63, 0.72, 0.37, 0.1, 0.45, 0.58, 0.66, 0.02, 0.47, 0.41, 0.19, 0.14, 0.56, 0.05, 0.04, 0.28, 0.42, 0.25, 0.36, 0.65, 0.47, 0.84, 0.09, 0.27, 0.98, 0.19, 0.26, 0.02, 0.4, 0.37, 0.0, 0.3, 0.48, 0.02, 0.12, 0.39, 0.38, 0.03, 0.3, 0.69, 0.22, 0.49, 0.05, 0.24, 0.76, 0.53, 0.82, 0.38, 0.76, 0.58, 0.96, 0.94, 0.96, 1.0, 0.91, 0.97, 0.87, 0.87, 0.88, 0.59, 0.84, 0.76, 0.92, 0.9, 0.95, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 1.0, 0.92, 0.99, 1.0, 1.0, 1.0, 0.94, 1.0, 0.94, 1.0, 0.99, 0.96, 0.92, 0.82, 0.88, 0.66, 0.82, 0.85, 0.57, 0.77, 0.85, 0.9, 0.93, 0.93, 0.88, 0.75, 0.84, 0.74, 0.9, 0.9, 0.91, 0.99, 0.97, 1.0, 1.0, 1.0, 0.99, 0.98, 0.89, 0.98, 0.86, 0.97, 0.97, 0.85, 1.0, 0.98, 0.89, 0.98, 0.99, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 0.91, 0.98, 0.88, 0.94, 1.0, 0.9, 0.96, 0.94, 0.9, 0.96, 0.71, 0.52, 0.68, 0.67, 0.55, 0.64, 0.74, 0.51, 0.74, 0.5, 0.63, 0.51, 0.55, 0.58, 0.59, 0.75, 0.58, 0.76, 0.45, 0.8, 0.59, 0.62, 0.87, 0.78, 0.83, 0.79, 0.74, 0.83, 0.79, 0.88, 0.83, 0.85, 0.92, 0.9, 0.95, 0.97, 0.74, 0.82, 0.72, 0.84, 0.91, 0.88, 0.93, 0.94, 0.92, 0.9, 0.9, 0.94, 0.9, 1.0, 0.97, 1.0, 0.97, 1.0, 1.0, 0.97, 1.0, 0.95, 1.0, 0.87, 0.96, 0.9, 0.98, 0.96, 0.82, 0.97, 0.88, 1.0, 1.0, 0.99, 1.0, 0.98, 0.99, 1.0, 0.99, 1.0, 1.0, 0.98, 1.0, 0.98, 0.99, 0.88, 0.99, 0.79, 1.0, 0.95, 0.97, 0.92, 0.97, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.96, 0.93, 0.97, 0.92, 0.96, 0.97, 0.94, 0.95, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.89, 0.99, 0.88, 0.96, 0.87, 0.96, 0.96, 0.98, 0.99, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 0.99, 0.98, 0.99, 0.96, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.97, 0.97, 0.82, 0.93, 0.89, 0.91, 0.9, 0.88, 0.82, 0.82, 0.87, 0.85, 0.95, 0.82, 0.93, 0.93, 0.87, 0.81, 0.8, 0.92, 0.8, 0.81, 0.92, 0.91, 0.93, 0.97, 0.77, 0.92, 0.91, 0.86, 0.91, 0.89, 0.9, 0.93, 0.94, 0.97, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.96, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.93, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.89, 1.0, 0.87, 1.0, 0.87, 1.0, 0.87, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 0.94, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.95, 1.0, 0.94, 0.9, 0.96, 0.91, 0.99, 0.91, 0.98, 0.91, 0.96, 1.0, 0.94, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 1.0, 0.99, 1.0, 0.98, 1.0, 0.97, 0.92, 0.92, 0.9, 0.95, 0.89, 0.93, 0.95, 1.0, 0.91, 0.84, 0.95, 0.86, 0.83, 0.89, 0.83, 0.86, 0.85, 0.83, 0.9, 0.92, 0.97, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 0.88, 1.0, 0.92, 0.99, 0.86, 0.95, 0.85, 0.95, 0.86, 0.98, 0.93, 0.98, 0.99, 0.99, 1.0, 1.0, 1.0, 0.84, 0.86, 0.79, 0.88, 0.99, 0.98, 0.98, 0.95, 1.0, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.98, 1.0, 1.0, 0.95, 0.98, 0.96, 0.92, 0.99, 0.88, 0.99, 0.97, 0.95, 0.98, 0.92, 0.94, 0.94, 0.95, 0.97, 0.98, 1.0, 1.0, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 57.694499
| 0.778604
| 1,001
|
O43791
|
Q15059
|
nan, 28805821
|
degron_data, UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
BRD3
|
MSTATTVAPAGIPATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVELLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSESGSSSSSGSSSDSSDSE
|
Homo sapiens
|
Nucleus, Chromosome
|
Low tissue specificity
|
{'Ciliated cells': '20.7', 'Basal respiratory cells': '18.6', 'Club cells': '27.1', 'Ionocytes': '17.3', 'Mucus glandular cells': '33.7', 'Serous glandular cells': '18.0', 'Gastric mucus-secreting cells': '20.6', 'Proximal enterocytes': '16.0', 'Paneth cells': '19.2', 'Distal enterocytes': '19.8', 'Intestinal goblet cells': '23.8', 'Exocrine glandular cells': '-0.647', 'Basal prostatic cells': '33.6', 'Prostatic glandular cells': '37.6', 'Breast glandular cells': '0.510', 'Breast myoepithelial cells': '0.355', 'Glandular and luminal cells': '26.0', 'Secretory cells': '24.6', 'Basal keratinocytes': '29.6', 'Suprabasal keratinocytes': '27.2', 'Basal squamous epithelial cells': '38.6', 'Squamous epithelial cells': '29.2', 'Alveolar cells type 1': '0.326', 'Alveolar cells type 2': '-0.152', 'Salivary duct cells': '40.9', 'Ductal cells': '0.671', 'Hepatocytes': '0.454', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.160', 'Distal tubular cells': '24.6', 'Collecting duct cells': '25.3', 'Mesothelial cells': '0.414', 'Sertoli cells': '-0.214', 'Granulosa cells': '23.8', 'Enteroendocrine cells': '42.0', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '-0.195', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '16.1', 'Cone photoreceptor cells': '32.3', 'Rod photoreceptor cells': '59.0', 'Bipolar cells': '55.7', 'Horizontal cells': '33.4', 'Astrocytes': '12.4', 'Oligodendrocyte precursor cells': '11.8', 'Oligodendrocytes': '18.0', 'Microglial cells': '9.8', 'Muller glia cells': '42.6', 'Schwann cells': '0.135', 'Spermatogonia': '0.202', 'Spermatocytes': '0.298', 'Early spermatids': '0.311', 'Late spermatids': '0.283', 'Oocytes': '22.1', 'Cytotrophoblasts': '26.2', 'Syncytiotrophoblasts': '27.6', 'Extravillous trophoblasts': '20.0', 'Endothelial cells': '29.7', 'Lymphatic endothelial cells': '43.6', 'Cardiomyocytes': '0.634', 'Skeletal myocytes': '-0.118', 'Smooth muscle cells': '33.9', 'Adipocytes': '27.7', 'Melanocytes': '0.211', 'Fibroblasts': '30.7', 'Peritubular cells': '-0.032', 'Endometrial stromal cells': '37.5', 'Ovarian stromal cells': '32.6', 'Undifferentiated cells': '36.5', 'T-cells': '25.7', 'B-cells': '21.0', 'Plasma cells': '7.2', 'Nk-cells': '26.4', 'Granulocytes': '22.3', 'Monocytes': '27.3', 'Macrophages': '26.2', 'Hofbauer cells': '18.8', 'Kupffer cells': '31.1', 'Dendritic cells': '37.2', 'Langerhans cells': '0.351', 'Erythroid cells': '-0.043', 'Adipocytes (Subcutaneous)': '-0.013', 'Adipocytes (Visceral)': '-0.102', 'Breast glandular cells (progenitors)': '0.419', 'Adipocytes (Breast)': '-0.233', 'Colon enterocytes': '-0.139', 'Colon enteroendocrine cells': '0.229', 'Enteric glia cells': '-0.170', 'Mitotic cells (Colon)': '-0.186', 'Mitotic cells (Heart)': '0.476', 'Podocytes': '-0.113', 'Ascending Loop of Henle cells': '0.542', 'Intercalated cells': '0.023', 'Cholangiocyte': '0.197', 'NK-cells (Liver)': '-0.238', 'Respiratory ciliated cells': '0.072', 'Mitotic cells (Lung)': '-0.099', 'NK-cells (Lung)': '0.237', 'B-cells (Lung)': '0.031', 'Alpha cells': '0.464', 'Beta cells': '0.292', 'Prostate glandular cells': '-0.166', 'Prostate basal glandular cells': '0.178', 'Urothelial cells': '0.095', 'Keratinocyte (other)': '0.401', 'Keratinocyte (granular)': '0.103', 'Hair cortex cells': '-0.124', 'Inner root sheath cells': '-0.025', 'Outer root sheath cells': '0.080', 'Sebaceous gland cells': '0.074', 'Eccrine sweat gland cells': '-0.129', 'Adipocytes (Skin)': '-0.163', 'Mitotic cells (Skin)': '0.313', 'Parietal cells': '-0.638', 'Chief cells': '-0.537', 'Gastric mucous cells': '-0.442', 'Gastric enteroendocrine cells': '-0.394', 'Mitotic cells (Stomach)': '0.005', 'Parafollicular cells': '0.063', 'Thyroid glandular cells': '0.426', 'Mitotic cells (Thyroid)': '-0.071', 'Adrenal cortex cells': '0.665', 'Adrenal medulla cells': '0.025', 'Mitotic cells (Adrenal gland)': '0.382', 'Minor salivary glandular cells': '0.612', 'Minor salivary gland ductal cells': '0.234', 'Minor salivary gland basal cells': '0.226', 'Mitotic cells (Minor salivary gland)': '0.310', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.118', 'Lactotropes': '-0.004', 'Gonadotropes': '0.148', 'Corticotropes': '-0.061', 'Thyrotropes': '0.189', 'Undifferentiated cells (Pituitary gland)': '0.379', 'Mitotic cells (Spleen)': '-0.180', 'Platelets': '-0.121', 'Erythrocytes': '-0.134', 'Hematopoietic stem cells': '-0.227', 'B-cells (Spleen)': '0.257', 'NK-cells (Spleen)': '0.332', 'Amygdala excitatory': '17.8', 'Cerebellar inhibitory': '17.1', 'Cge interneuron': '34.6', 'Deep-layer corticothalamic and 6b': '20.3', 'Deep-layer intratelencephalic': '21.0', 'Deep-layer near-projecting': '20.7', 'Eccentric medium spiny neuron': '24.6', 'Hippocampal ca1-3': '18.4', 'Hippocampal ca4': '14.6', 'Hippocampal dentate gyrus': '19.2', 'Lamp5-lhx6 and chandelier': '30.0', 'Lower rhombic lip': '13.8', 'Mammillary body': '18.1', 'Medium spiny neuron': '19.4', 'Mge interneuron': '22.8', 'Midbrain-derived inhibitory': '28.4', 'Miscellaneous': '21.9', 'Splatter': '19.0', 'Thalamic excitatory': '16.3', 'Upper rhombic lip': '26.8', 'Upper-layer intratelencephalic': '19.3', 'Astrocyte': '22.9', 'Bergmann glia': '23.1', 'Central nervous system macrophage': '33.2', 'Choroid plexus epithelial cell': '13.8', 'Committed oligodendrocyte precursor': '27.7', 'Ependymal cell': '29.6', 'Oligodendrocyte': '27.0', 'Oligodendrocyte precursor cell': '25.6', 'Endothelial cell': '20.0', 'Pericyte': '26.7', 'Vascular associated smooth muscle cell': '28.6', 'Fibroblast': '25.1', 'Leukocyte': '29.2', 'Basophil': '62.6', 'Eosinophil': '15.8', 'Neutrophil': '67.0', 'Classical monocyte': '12.7', 'Non-classical monocyte': '11.0', 'Intermediate monocyte': '57.8', 'T-reg': '47.9', 'GdT-cell': '11.5', 'MAIT T-cell': '55.0', 'Memory CD4 T-cell': '9.2', 'Naive CD4 T-cell': '12.6', 'Memory CD8 T-cell': '10.2', 'Naive CD8 T-cell': '12.6', 'Memory B-cell': '6.9', 'Naive B-cell': '8.4', 'Plasmacytoid DC': '86.4', 'Myeloid DC': '79.8', 'NK-cell': '16.2', 'Total PBMC': '62.8', 'Vd2 gdTCR': '67.0', 'Memory CD4 T-cell Th1\\/Th17': '11.6', 'Memory CD4 T-cell Th17': '13.2', 'Memory CD4 T-cell Th2': '14.8', 'Non-Vd2 gdTCR': '64.0', 'Memory CD4 T-cell Th1': '14.8', 'Memory CD4 T-cell TFH': '20.0', 'Terminal effector memory CD4 T-cell': '66.7', 'Central memory CD8 T-cell': '58.3', 'Effector memory CD8 T-cell': '62.9', 'Terminal effector memory CD8 T-cell': '65.5', 'Non-switched memory B-cell': '49.4', 'Plasmablast': '12.2', 'Switched memory B-cell': '53.5', 'Exhausted memory B-cell': '51.5', 'Progenitor cell': '78.5', 'Memory T-reg': '13.5', 'Naive CD4 T-cell activated': '10.2', 'Naive CD8 T-cell activated': '12.8', 'Naive T-reg': '15.9'}
|
2E7N, 2NXB, 2OO1, 2YW5, 3S91, 3S92, 5A7C, 5HFR, 5HJC, 6BGG, 6BGH, 6I41, 6I5P, 6I68, 6I7A, 6QJU, 6U4A, 6ULP, 7JMY, 7JQ8, 7JYN, 7JYZ, 7L72, 7L9L, 7LAY, 7LAZ, 7LB4, 7LBT, 7R8R, 7RJK, 7RJL, 7RJM, 7RJN, 7S3P, 7TO7, 7TO8, 7TO9, 7TOA, 7UG5, 8B5A, 8CV5
|
{'Adipose Tissue': 14.20306561461794, 'Adrenal Gland': 12.062472868217052, 'Bladder': 18.583809523809524, 'Blood': 5.209989773950484, 'Blood Vessel': 18.005731086142323, 'Brain': 10.0167765329296, 'Breast': 15.53139433551198, 'Cervix Uteri': 21.99684210526316, 'Colon': 17.85560975609756, 'Esophagus': 15.778703806228371, 'Fallopian Tube': 22.27111111111111, 'Heart': 5.604905923344948, 'Kidney': 6.707033707865169, 'Liver': 5.331274336283186, 'Lung': 15.111891003460208, 'Muscle': 11.096579078455791, 'Nerve': 24.28967689822294, 'Ovary': 19.518255555555555, 'Pancreas': 5.31865243902439, 'Pituitary': 13.757303886925795, 'Prostate': 17.421624489795917, 'Salivary Gland': 12.447154320987655, 'Skin': 15.802720840243229, 'Small Intestine': 12.856278074866308, 'Spleen': 12.300593360995853, 'Stomach': 11.29818105849582, 'Testis': 20.507091412742383, 'Thyroid': 20.918497702909647, 'Uterus': 26.201359154929577, 'Vagina': 16.397596153846155}
|
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60.04, 53.31]
|
[0.99, 0.99, 0.94, 0.96, 0.87, 0.98, 0.89, 0.96, 0.98, 0.91, 0.89, 0.96, 0.87, 0.9, 0.91, 0.94, 0.7, 0.8, 0.84, 0.37, 0.54, 0.97, 0.76, 0.25, 0.42, 0.27, 0.55, 0.32, 0.87, 0.83, 0.54, 0.69, 0.3, 0.28, 0.58, 0.01, 0.25, 0.1, 0.05, 0.53, 0.16, 0.0, 0.3, 0.44, 0.29, 0.01, 0.05, 0.53, 0.31, 0.02, 0.32, 0.77, 0.27, 0.45, 0.25, 0.0, 0.69, 0.38, 0.07, 0.29, 0.66, 0.42, 0.27, 0.35, 0.09, 0.5, 0.84, 0.62, 0.78, 0.24, 0.68, 0.39, 0.08, 0.32, 0.67, 0.5, 0.03, 0.76, 0.69, 0.26, 0.14, 0.03, 0.01, 0.04, 0.04, 0.0, 0.34, 0.47, 0.08, 0.08, 0.46, 0.48, 0.3, 0.27, 0.03, 0.47, 0.23, 0.0, 0.59, 0.33, 0.0, 0.22, 0.61, 0.12, 0.0, 0.38, 0.21, 0.04, 0.01, 0.46, 0.1, 0.06, 0.36, 0.59, 0.25, 0.28, 0.69, 0.82, 0.89, 0.36, 0.66, 0.3, 0.04, 0.58, 0.09, 0.0, 0.48, 0.25, 0.0, 0.28, 0.75, 0.21, 0.03, 0.59, 0.63, 0.25, 0.2, 0.72, 0.58, 0.09, 0.48, 0.83, 0.73, 0.37, 0.48, 0.53, 0.37, 0.88, 0.91, 0.93, 0.78, 0.91, 0.9, 0.78, 0.91, 0.82, 0.92, 0.94, 0.94, 0.93, 0.99, 0.96, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.8, 1.0, 0.9, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.92, 0.99, 0.93, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.96, 0.98, 0.96, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.98, 1.0, 0.98, 0.99, 0.94, 0.99, 0.95, 0.92, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.92, 0.97, 0.94, 1.0, 1.0, 1.0, 0.93, 1.0, 0.88, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.97, 1.0, 1.0, 0.97, 1.0, 0.94, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 1.0, 0.85, 0.89, 0.86, 0.88, 0.81, 0.74, 0.93, 0.96, 0.62, 0.98, 0.2, 0.38, 0.63, 0.14, 0.04, 0.48, 0.25, 0.0, 0.19, 0.5, 0.03, 0.02, 0.61, 0.19, 0.0, 0.35, 0.3, 0.89, 0.76, 0.04, 0.34, 0.82, 0.12, 0.0, 0.67, 0.4, 0.06, 0.24, 0.81, 0.66, 0.36, 0.53, 0.12, 0.86, 0.74, 0.6, 0.75, 0.26, 0.77, 0.44, 0.1, 0.54, 0.66, 0.36, 0.02, 0.67, 0.71, 0.45, 0.19, 0.04, 0.0, 0.35, 0.13, 0.0, 0.45, 0.59, 0.21, 0.04, 0.51, 0.6, 0.53, 0.58, 0.07, 0.83, 0.52, 0.11, 0.6, 0.25, 0.0, 0.0, 0.52, 0.1, 0.0, 0.37, 0.28, 0.02, 0.0, 0.46, 0.11, 0.08, 0.3, 0.62, 0.25, 0.23, 0.59, 0.83, 0.88, 0.5, 0.69, 0.18, 0.07, 0.57, 0.2, 0.0, 0.56, 0.52, 0.0, 0.23, 0.59, 0.12, 0.0, 0.32, 0.53, 0.38, 0.14, 0.79, 0.57, 0.16, 0.61, 0.89, 0.68, 0.8, 0.78, 0.9, 0.76, 0.79, 0.83, 0.9, 0.91, 0.85, 0.96, 0.85, 0.92, 0.93, 0.96, 0.91, 0.97, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.95, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 0.97, 0.81, 0.39, 0.5, 0.8, 0.76, 0.47, 0.61, 0.5, 0.58, 0.48, 0.56, 0.49, 0.56, 0.55, 0.6, 0.71, 0.5, 0.65, 0.71, 0.42, 0.49, 0.71, 0.69, 0.62, 0.58, 0.32, 0.66, 0.73, 0.76, 0.78, 0.54, 0.74, 0.78, 0.84, 0.87, 0.94, 0.98, 1.0, 1.0, 1.0, 0.99, 0.99, 0.88, 0.77, 0.94, 0.93, 0.9, 0.84, 0.78, 0.92, 0.95, 0.94, 0.8, 0.94, 0.95, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.98, 0.96, 0.92, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 0.96, 0.99, 0.99, 0.99, 0.91, 0.92, 0.83, 0.89, 0.89, 0.56, 0.73, 0.78, 0.75, 0.75, 0.53, 0.35, 0.64, 0.59, 0.7, 0.07, 0.51, 0.7, 0.68, 0.3, 0.14, 0.28, 0.45, 0.02, 0.27, 0.27, 0.17, 0.09, 0.77, 0.61, 0.11, 0.56, 0.61, 0.88, 0.4, 0.39, 0.57, 0.54, 0.02, 0.21, 0.51, 0.1, 0.01, 0.24, 0.61, 0.39, 0.06, 0.64, 0.82, 0.21, 0.64, 0.94, 0.33, 0.52, 0.67, 0.89, 0.79, 0.23, 0.87, 0.31, 0.49, 0.15, 0.66, 0.68, 0.05, 0.44, 0.35, 0.43, 0.0, 0.01, 0.09, 0.22, 0.0, 0.16, 0.42, 0.19, 0.03, 0.43, 0.59, 0.37, 0.39, 0.53, 0.88, 0.73, 0.93, 0.89, 0.93, 0.86, 0.98, 0.88, 1.0, 1.0, 0.94, 0.99, 0.99, 0.96, 0.97, 0.95, 0.57, 0.54, 0.86, 0.68, 0.41, 0.53, 0.52, 0.58, 0.46, 0.65, 0.67, 0.71, 0.51, 0.62, 0.55, 0.56, 0.58, 0.65, 0.73, 0.5, 0.62, 0.57, 0.45, 0.82, 0.82, 0.76, 0.83, 0.99, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 67.886267
| 0.679063
| 251
|
O43791
|
Q16828
|
24656772
|
UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
DUSP6
|
MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST
|
Homo sapiens
|
Cytoplasm
|
Tissue enhanced (salivary)
|
{'Ciliated cells': '36.5', 'Basal respiratory cells': '91.6', 'Club cells': '43.2', 'Ionocytes': '67.0', 'Mucus glandular cells': '37.0', 'Serous glandular cells': '92.5', 'Gastric mucus-secreting cells': '21.2', 'Proximal enterocytes': '14.0', 'Paneth cells': '4.5', 'Distal enterocytes': '30.5', 'Intestinal goblet cells': '12.2', 'Exocrine glandular cells': '-0.600', 'Basal prostatic cells': '21.0', 'Prostatic glandular cells': '2.1', 'Breast glandular cells': '-0.056', 'Breast myoepithelial cells': '0.078', 'Glandular and luminal cells': '140.0', 'Secretory cells': '33.8', 'Basal keratinocytes': '67.1', 'Suprabasal keratinocytes': '19.9', 'Basal squamous epithelial cells': '25.7', 'Squamous epithelial cells': '12.2', 'Alveolar cells type 1': '0.181', 'Alveolar cells type 2': '0.022', 'Salivary duct cells': '32.4', 'Ductal cells': '0.575', 'Hepatocytes': '-0.043', 'Cholangiocytes': '82.0', 'Proximal tubular cells': '0.087', 'Distal tubular cells': '15.4', 'Collecting duct cells': '140.0', 'Mesothelial cells': '-0.202', 'Sertoli cells': '0.108', 'Granulosa cells': '31.2', 'Enteroendocrine cells': '13.7', 'Pancreatic endocrine cells': '15.3', 'Leydig cells': '0.304', 'Excitatory neurons': '19.0', 'Inhibitory neurons': '3.6', 'Cone photoreceptor cells': '18.7', 'Rod photoreceptor cells': '3.3', 'Bipolar cells': '4.3', 'Horizontal cells': '5.7', 'Astrocytes': '11.8', 'Oligodendrocyte precursor cells': '23.1', 'Oligodendrocytes': '2.3', 'Microglial cells': '32.2', 'Muller glia cells': '18.1', 'Schwann cells': '0.206', 'Spermatogonia': '0.268', 'Spermatocytes': '0.135', 'Early spermatids': '-0.075', 'Late spermatids': '-0.378', 'Oocytes': '2.2', 'Cytotrophoblasts': '72.3', 'Syncytiotrophoblasts': '44.9', 'Extravillous trophoblasts': '1.7', 'Endothelial cells': '138.8', 'Lymphatic endothelial cells': '184.9', 'Cardiomyocytes': '-0.265', 'Skeletal myocytes': '0.109', 'Smooth muscle cells': '23.7', 'Adipocytes': '174.5', 'Melanocytes': '-0.115', 'Fibroblasts': '45.7', 'Peritubular cells': '0.262', 'Endometrial stromal cells': '14.1', 'Ovarian stromal cells': '6.2', 'Undifferentiated cells': '16.4', 'T-cells': '38.4', 'B-cells': '14.6', 'Plasma cells': '15.2', 'Nk-cells': '34.9', 'Granulocytes': '335.2', 'Monocytes': '199.9', 'Macrophages': '229.5', 'Hofbauer cells': '83.6', 'Kupffer cells': '213.5', 'Dendritic cells': '19.4', 'Langerhans cells': '-0.031', 'Erythroid cells': '0.040', 'Adipocytes (Subcutaneous)': '-0.074', 'Adipocytes (Visceral)': '0.372', 'Breast glandular cells (progenitors)': '0.006', 'Adipocytes (Breast)': '0.158', 'Colon enterocytes': '0.071', 'Colon enteroendocrine cells': '0.301', 'Enteric glia cells': '0.107', 'Mitotic cells (Colon)': '0.208', 'Mitotic cells (Heart)': '0.165', 'Podocytes': '0.091', 'Ascending Loop of Henle cells': '0.019', 'Intercalated cells': '-0.068', 'Cholangiocyte': '0.252', 'NK-cells (Liver)': '-0.062', 'Respiratory ciliated cells': '-0.065', 'Mitotic cells (Lung)': '-0.039', 'NK-cells (Lung)': '0.172', 'B-cells (Lung)': '0.013', 'Alpha cells': '0.360', 'Beta cells': '0.161', 'Prostate glandular cells': '-0.256', 'Prostate basal glandular cells': '0.276', 'Urothelial cells': '0.333', 'Keratinocyte (other)': '-0.483', 'Keratinocyte (granular)': '-0.207', 'Hair cortex cells': '0.229', 'Inner root sheath cells': '0.202', 'Outer root sheath cells': '0.308', 'Sebaceous gland cells': '0.378', 'Eccrine sweat gland cells': '0.415', 'Adipocytes (Skin)': '0.378', 'Mitotic cells (Skin)': '0.044', 'Parietal cells': '-0.630', 'Chief cells': '-0.589', 'Gastric mucous cells': '-0.415', 'Gastric enteroendocrine cells': '-0.387', 'Mitotic cells (Stomach)': '0.003', 'Parafollicular cells': '0.047', 'Thyroid glandular cells': '0.184', 'Mitotic cells (Thyroid)': '0.160', 'Adrenal cortex cells': '-0.086', 'Adrenal medulla cells': '0.109', 'Mitotic cells (Adrenal gland)': '0.006', 'Minor salivary glandular cells': '0.716', 'Minor salivary gland ductal cells': '0.369', 'Minor salivary gland basal cells': '-0.384', 'Mitotic cells (Minor salivary gland)': '-0.618', 'Adipocytes (Minor salivary gland)': '-0.121', 'Somatotropes': '-0.154', 'Lactotropes': '-0.269', 'Gonadotropes': '-0.115', 'Corticotropes': '-0.304', 'Thyrotropes': '0.013', 'Undifferentiated cells (Pituitary gland)': '0.402', 'Mitotic cells (Spleen)': '-0.237', 'Platelets': '0.196', 'Erythrocytes': '0.053', 'Hematopoietic stem cells': '-0.013', 'B-cells (Spleen)': '-0.004', 'NK-cells (Spleen)': '0.179', 'Amygdala excitatory': '11.7', 'Cerebellar inhibitory': '7.3', 'Cge interneuron': '4.1', 'Deep-layer corticothalamic and 6b': '17.1', 'Deep-layer intratelencephalic': '20.5', 'Deep-layer near-projecting': '12.2', 'Eccentric medium spiny neuron': '13.3', 'Hippocampal ca1-3': '37.2', 'Hippocampal ca4': '25.5', 'Hippocampal dentate gyrus': '0.9', 'Lamp5-lhx6 and chandelier': '8.0', 'Lower rhombic lip': '1.8', 'Mammillary body': '2.3', 'Medium spiny neuron': '9.4', 'Mge interneuron': '5.0', 'Midbrain-derived inhibitory': '1.5', 'Miscellaneous': '19.8', 'Splatter': '5.0', 'Thalamic excitatory': '25.6', 'Upper rhombic lip': '7.0', 'Upper-layer intratelencephalic': '13.9', 'Astrocyte': '7.0', 'Bergmann glia': '10.1', 'Central nervous system macrophage': '21.9', 'Choroid plexus epithelial cell': '1.2', 'Committed oligodendrocyte precursor': '2.8', 'Ependymal cell': '3.4', 'Oligodendrocyte': '1.8', 'Oligodendrocyte precursor cell': '34.9', 'Endothelial cell': '65.1', 'Pericyte': '8.5', 'Vascular associated smooth muscle cell': '7.5', 'Fibroblast': '53.6', 'Leukocyte': '44.0', 'Basophil': '5960.9', 'Eosinophil': '248.0', 'Neutrophil': '1469.0', 'Classical monocyte': '199.3', 'Non-classical monocyte': '165.4', 'Intermediate monocyte': '1454.7', 'T-reg': '16.5', 'GdT-cell': '9.9', 'MAIT T-cell': '25.2', 'Memory CD4 T-cell': '2.7', 'Naive CD4 T-cell': '9.4', 'Memory CD8 T-cell': '3.5', 'Naive CD8 T-cell': '4.2', 'Memory B-cell': '2.7', 'Naive B-cell': '17.0', 'Plasmacytoid DC': '88.6', 'Myeloid DC': '128.9', 'NK-cell': '29.0', 'Total PBMC': '559.0', 'Vd2 gdTCR': '24.9', 'Memory CD4 T-cell Th1\\/Th17': '15.6', 'Memory CD4 T-cell Th17': '12.0', 'Memory CD4 T-cell Th2': '17.8', 'Non-Vd2 gdTCR': '29.7', 'Memory CD4 T-cell Th1': '14.6', 'Memory CD4 T-cell TFH': '8.4', 'Terminal effector memory CD4 T-cell': '18.5', 'Central memory CD8 T-cell': '15.4', 'Effector memory CD8 T-cell': '23.5', 'Terminal effector memory CD8 T-cell': '21.9', 'Non-switched memory B-cell': '94.0', 'Plasmablast': '45.1', 'Switched memory B-cell': '64.2', 'Exhausted memory B-cell': '100.6', 'Progenitor cell': '142.6', 'Memory T-reg': '8.3', 'Naive CD4 T-cell activated': '33.4', 'Naive CD8 T-cell activated': '2.3', 'Naive T-reg': '5.6'}
|
1HZM, 1MKP
|
{'Adipose Tissue': 81.8846926910299, 'Adrenal Gland': 17.26237984496124, 'Bladder': 33.917142857142856, 'Blood': 21.017344165769646, 'Blood Vessel': 30.908373782771537, 'Brain': 14.809812641937926, 'Breast': 67.25331154684096, 'Cervix Uteri': 29.240578947368423, 'Colon': 30.795822849807447, 'Esophagus': 28.40838339100346, 'Fallopian Tube': 44.61666666666667, 'Heart': 18.108304297328687, 'Kidney': 35.635011235955055, 'Liver': 35.01407522123893, 'Lung': 89.63671280276816, 'Muscle': 5.409979576587796, 'Nerve': 56.116558966074315, 'Ovary': 13.14835, 'Pancreas': 7.010475609756098, 'Pituitary': 29.676042402826855, 'Prostate': 29.085073469387755, 'Salivary Gland': 61.78445061728395, 'Skin': 23.62817965726921, 'Small Intestine': 34.794828877005344, 'Spleen': 82.04356846473028, 'Stomach': 21.526119777158776, 'Testis': 9.241484764542935, 'Thyroid': 46.06701684532925, 'Uterus': 28.569035211267604, 'Vagina': 23.227115384615384}
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[45.12, 35.86, 37.42, 42.1, 42.68, 40.09, 32.49, 36.92, 34.71, 31.81, 33.06, 32.92, 35.51, 44.14, 56.33, 80.12, 87.44, 91.02, 91.19, 89.04, 89.41, 93.14, 91.95, 88.59, 89.64, 89.73, 87.4, 85.57, 87.55, 80.75, 78.71, 76.48, 82.69, 87.23, 87.53, 90.57, 89.19, 89.85, 87.89, 85.87, 81.56, 81.22, 77.09, 80.7, 84.52, 81.93, 76.38, 80.78, 87.3, 89.62, 86.39, 84.03, 89.0, 86.32, 87.13, 80.25, 68.94, 68.28, 66.69, 62.38, 62.39, 65.81, 67.08, 64.34, 65.1, 66.82, 65.07, 64.14, 62.94, 65.01, 66.62, 69.26, 69.93, 70.69, 67.24, 67.54, 68.65, 61.36, 64.27, 63.39, 68.8, 69.5, 68.72, 67.5, 68.43, 70.65, 68.8, 68.85, 71.92, 66.76, 66.43, 70.93, 81.27, 86.42, 88.45, 91.62, 91.54, 91.0, 87.33, 83.66, 82.67, 76.95, 67.21, 59.64, 62.43, 58.78, 57.13, 50.41, 51.98, 54.12, 57.78, 64.49, 73.1, 76.27, 82.9, 80.04, 79.52, 80.97, 84.39, 81.27, 79.5, 82.52, 82.67, 81.06, 78.01, 80.04, 82.26, 86.9, 88.59, 91.25, 90.97, 91.56, 89.16, 81.54, 87.21, 87.88, 79.99, 81.26, 85.6, 83.31, 72.01, 79.65, 82.71, 75.63, 79.08, 82.51, 81.71, 80.43, 70.58, 58.58, 49.42, 36.95, 35.42, 33.48, 26.03, 34.7, 31.66, 35.73, 33.69, 38.71, 39.66, 36.96, 37.11, 41.26, 37.84, 38.72, 47.18, 40.59, 44.7, 41.94, 46.01, 45.0, 35.98, 44.02, 36.26, 40.99, 42.56, 45.56, 44.39, 48.81, 46.35, 49.31, 43.59, 53.41, 47.66, 48.57, 45.87, 43.35, 41.54, 47.57, 41.45, 53.43, 37.97, 45.63, 37.9, 38.67, 37.46, 33.75, 34.49, 29.68, 27.99, 33.11, 42.82, 47.61, 60.07, 73.14, 89.75, 93.67, 96.86, 97.81, 97.09, 97.19, 98.07, 98.61, 98.55, 98.0, 93.8, 90.1, 89.37, 88.48, 90.82, 92.53, 91.29, 90.39, 93.5, 92.61, 90.85, 95.31, 94.11, 93.83, 94.41, 96.04, 97.73, 97.64, 98.56, 98.44, 98.76, 98.35, 98.44, 92.41, 89.23, 86.01, 86.91, 90.57, 94.71, 92.45, 93.21, 91.0, 89.31, 87.53, 83.98, 89.88, 96.51, 97.6, 98.01, 98.19, 98.29, 98.43, 96.61, 94.28, 88.55, 88.29, 83.68, 78.95, 86.62, 91.22, 96.72, 98.08, 97.91, 97.92, 98.55, 98.59, 98.11, 98.22, 98.76, 98.69, 98.63, 98.79, 98.79, 98.47, 98.52, 98.4, 98.07, 97.86, 97.55, 97.24, 97.27, 98.22, 98.75, 98.63, 98.75, 97.47, 94.45, 86.97, 83.54, 91.4, 89.71, 93.65, 97.96, 98.25, 98.21, 98.64, 98.84, 98.79, 98.73, 98.75, 98.78, 98.57, 98.38, 97.71, 97.55, 96.67, 95.96, 96.16, 96.75, 96.89, 95.65, 96.86, 97.92, 97.39, 96.42, 96.95, 96.46, 92.43, 92.74, 91.81, 86.52, 83.92, 81.23, 86.83, 86.56, 90.65, 86.58, 88.79, 91.74, 96.82, 95.85, 95.93, 98.23, 98.19, 96.77, 96.75, 97.63, 97.21, 95.11, 95.19, 94.88, 88.11, 79.85, 64.54, 62.41, 57.55, 55.77, 53.19, 49.46, 52.44, 42.82, 47.29, 46.63, 49.75, 56.0, 64.51, 73.65, 77.63, 74.27, 68.54, 66.09, 71.08, 56.61, 64.53, 70.62, 70.24, 74.73, 70.47, 64.37, 61.84, 56.17, 52.71, 39.42, 40.5, 38.71]
|
[0.99, 1.0, 0.99, 0.93, 0.96, 0.93, 0.9, 0.9, 0.86, 0.96, 0.88, 0.73, 0.99, 0.85, 0.44, 0.28, 0.24, 0.21, 0.47, 0.02, 0.52, 0.25, 0.0, 0.1, 0.56, 0.17, 0.18, 0.66, 0.69, 0.57, 0.34, 0.8, 0.64, 0.07, 0.0, 0.02, 0.0, 0.0, 0.1, 0.03, 0.55, 0.53, 0.73, 0.38, 0.18, 0.49, 0.37, 0.03, 0.05, 0.0, 0.51, 0.39, 0.09, 0.03, 0.22, 0.0, 0.31, 0.13, 0.52, 0.57, 0.79, 0.25, 0.21, 0.73, 0.54, 0.07, 0.54, 0.77, 0.44, 0.72, 0.08, 0.42, 0.0, 0.56, 0.5, 0.08, 0.1, 0.91, 0.72, 0.43, 0.8, 0.24, 0.49, 0.45, 0.32, 0.04, 0.6, 0.78, 0.18, 0.09, 0.79, 0.65, 0.06, 0.15, 0.0, 0.0, 0.0, 0.0, 0.22, 0.34, 0.7, 0.32, 0.58, 0.94, 0.25, 0.53, 0.61, 0.91, 0.72, 0.15, 0.44, 0.79, 0.46, 0.22, 0.07, 0.04, 0.13, 0.0, 0.01, 0.61, 0.23, 0.0, 0.38, 0.69, 0.43, 0.64, 0.21, 0.5, 0.07, 0.18, 0.09, 0.01, 0.28, 0.11, 0.0, 0.03, 0.41, 0.41, 0.0, 0.17, 0.38, 0.64, 0.23, 0.27, 0.79, 0.17, 0.16, 0.41, 0.37, 0.51, 0.26, 0.72, 0.71, 0.68, 0.95, 0.77, 0.95, 0.91, 0.94, 0.93, 0.93, 0.84, 0.95, 0.73, 0.96, 0.66, 0.82, 0.8, 0.91, 0.8, 0.9, 0.89, 0.9, 0.89, 0.98, 0.96, 0.99, 0.98, 0.99, 0.99, 0.95, 0.97, 0.9, 0.97, 0.98, 0.99, 1.0, 1.0, 1.0, 0.97, 1.0, 0.96, 1.0, 0.98, 1.0, 0.88, 1.0, 0.91, 0.94, 0.91, 0.75, 0.85, 0.43, 0.53, 0.61, 0.35, 0.03, 0.07, 0.45, 0.02, 0.23, 0.67, 0.34, 0.0, 0.08, 0.0, 0.03, 0.18, 0.15, 0.36, 0.09, 0.08, 0.51, 0.39, 0.39, 0.73, 0.17, 0.01, 0.54, 0.84, 0.25, 0.42, 0.0, 0.3, 0.09, 0.0, 0.0, 0.0, 0.0, 0.03, 0.4, 0.95, 0.29, 0.76, 0.19, 0.63, 0.16, 0.5, 0.97, 0.59, 0.78, 0.63, 0.1, 0.4, 0.14, 0.27, 0.41, 0.01, 0.54, 0.04, 0.35, 0.45, 0.5, 0.7, 0.8, 0.3, 0.45, 0.0, 0.27, 0.7, 0.27, 0.01, 0.63, 0.42, 0.01, 0.06, 0.6, 0.03, 0.0, 0.31, 0.32, 0.0, 0.21, 0.73, 0.6, 0.64, 0.18, 0.02, 0.0, 0.0, 0.0, 0.02, 0.01, 0.22, 0.32, 0.0, 0.17, 0.04, 0.07, 0.0, 0.0, 0.0, 0.01, 0.0, 0.0, 0.01, 0.0, 0.0, 0.0, 0.45, 0.5, 0.49, 0.69, 0.21, 0.11, 0.07, 0.49, 0.46, 0.0, 0.22, 0.53, 0.33, 0.0, 0.35, 0.86, 0.42, 0.07, 0.64, 0.14, 0.02, 0.59, 0.13, 0.23, 0.75, 0.28, 0.0, 0.25, 0.3, 0.09, 0.0, 0.39, 0.49, 0.11, 0.08, 0.52, 0.74, 0.33, 0.75, 0.22, 0.77, 0.18, 0.91, 0.68, 0.41, 0.81, 0.64, 0.52, 0.92, 0.89, 0.65, 0.58, 0.63, 0.69, 0.58, 0.62, 0.34, 0.92, 0.92, 0.58, 0.92, 0.49, 0.64, 0.49, 0.57, 0.53, 0.73, 0.88, 0.85, 0.92, 0.86, 0.97]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 75.544777
| 0.444016
| 1,889
|
O43791
|
Q16829
|
24656772
|
UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
DUSP7
|
MKNQLRGPPARAHMSTSGAAAAGGTRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWLQEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFATRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSSQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
|
Homo sapiens
|
Cytoplasm
|
Tissue enhanced (esophagus, skin)
|
{'Ciliated cells': '1.9', 'Basal respiratory cells': '12.2', 'Club cells': '4.2', 'Ionocytes': '4.0', 'Mucus glandular cells': '3.1', 'Serous glandular cells': '8.3', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '0.9', 'Paneth cells': '1.3', 'Distal enterocytes': '3.6', 'Intestinal goblet cells': '2.4', 'Exocrine glandular cells': '-0.565', 'Basal prostatic cells': '10.6', 'Prostatic glandular cells': '2.2', 'Breast glandular cells': '0.030', 'Breast myoepithelial cells': '0.063', 'Glandular and luminal cells': '2.5', 'Secretory cells': '3.7', 'Basal keratinocytes': '86.8', 'Suprabasal keratinocytes': '86.1', 'Basal squamous epithelial cells': '31.9', 'Squamous epithelial cells': '51.8', 'Alveolar cells type 1': '0.304', 'Alveolar cells type 2': '-0.087', 'Salivary duct cells': '9.5', 'Ductal cells': '0.607', 'Hepatocytes': '0.331', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '-0.031', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.151', 'Sertoli cells': '0.665', 'Granulosa cells': '4.9', 'Enteroendocrine cells': '4.9', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.463', 'Excitatory neurons': '5.3', 'Inhibitory neurons': '4.2', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.9', 'Bipolar cells': '2.7', 'Horizontal cells': '1.9', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '5.2', 'Oligodendrocytes': '18.9', 'Microglial cells': '5.4', 'Muller glia cells': '1.2', 'Schwann cells': '0.313', 'Spermatogonia': '0.560', 'Spermatocytes': '0.329', 'Early spermatids': '-0.345', 'Late spermatids': '-0.489', 'Oocytes': '8.8', 'Cytotrophoblasts': '0.6', 'Syncytiotrophoblasts': '0.9', 'Extravillous trophoblasts': '4.8', 'Endothelial cells': '20.3', 'Lymphatic endothelial cells': '3.6', 'Cardiomyocytes': '0.386', 'Skeletal myocytes': '-0.073', 'Smooth muscle cells': '8.7', 'Adipocytes': '15.6', 'Melanocytes': '0.075', 'Fibroblasts': '8.1', 'Peritubular cells': '0.305', 'Endometrial stromal cells': '7.3', 'Ovarian stromal cells': '2.5', 'Undifferentiated cells': '3.4', 'T-cells': '8.2', 'B-cells': '2.4', 'Plasma cells': '2.7', 'Nk-cells': '9.3', 'Granulocytes': '7.0', 'Monocytes': '6.5', 'Macrophages': '9.7', 'Hofbauer cells': '9.2', 'Kupffer cells': '12.5', 'Dendritic cells': '10.8', 'Langerhans cells': '0.059', 'Erythroid cells': '-0.124', 'Adipocytes (Subcutaneous)': '-0.241', 'Adipocytes (Visceral)': '-0.279', 'Breast glandular cells (progenitors)': '0.065', 'Adipocytes (Breast)': '0.033', 'Colon enterocytes': '-0.142', 'Colon enteroendocrine cells': '0.226', 'Enteric glia cells': '0.438', 'Mitotic cells (Colon)': '-0.081', 'Mitotic cells (Heart)': '0.477', 'Podocytes': '-0.024', 'Ascending Loop of Henle cells': '0.404', 'Intercalated cells': '-0.094', 'Cholangiocyte': '0.367', 'NK-cells (Liver)': '-0.184', 'Respiratory ciliated cells': '-0.133', 'Mitotic cells (Lung)': '-0.117', 'NK-cells (Lung)': '0.227', 'B-cells (Lung)': '-0.093', 'Alpha cells': '0.464', 'Beta cells': '0.280', 'Prostate glandular cells': '-0.321', 'Prostate basal glandular cells': '0.239', 'Urothelial cells': '0.461', 'Keratinocyte (other)': '0.333', 'Keratinocyte (granular)': '0.198', 'Hair cortex cells': '-0.224', 'Inner root sheath cells': '-0.184', 'Outer root sheath cells': '-0.258', 'Sebaceous gland cells': '-0.139', 'Eccrine sweat gland cells': '-0.382', 'Adipocytes (Skin)': '-0.346', 'Mitotic cells (Skin)': '-0.091', 'Parietal cells': '-0.597', 'Chief cells': '-0.443', 'Gastric mucous cells': '-0.309', 'Gastric enteroendocrine cells': '-0.257', 'Mitotic cells (Stomach)': '0.096', 'Parafollicular cells': '-0.023', 'Thyroid glandular cells': '0.057', 'Mitotic cells (Thyroid)': '0.076', 'Adrenal cortex cells': '0.273', 'Adrenal medulla cells': '0.358', 'Mitotic cells (Adrenal gland)': '-0.073', 'Minor salivary glandular cells': '-0.007', 'Minor salivary gland ductal cells': '-0.267', 'Minor salivary gland basal cells': '0.768', 'Mitotic cells (Minor salivary gland)': '0.697', 'Adipocytes (Minor salivary gland)': '0.184', 'Somatotropes': '-0.167', 'Lactotropes': '-0.176', 'Gonadotropes': '-0.050', 'Corticotropes': '-0.104', 'Thyrotropes': '-0.090', 'Undifferentiated cells (Pituitary gland)': '0.360', 'Mitotic cells (Spleen)': '-0.274', 'Platelets': '-0.054', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.233', 'B-cells (Spleen)': '0.036', 'NK-cells (Spleen)': '0.184', 'Amygdala excitatory': '5.4', 'Cerebellar inhibitory': '1.1', 'Cge interneuron': '8.9', 'Deep-layer corticothalamic and 6b': '7.3', 'Deep-layer intratelencephalic': '6.9', 'Deep-layer near-projecting': '3.6', 'Eccentric medium spiny neuron': '7.5', 'Hippocampal ca1-3': '5.6', 'Hippocampal ca4': '3.8', 'Hippocampal dentate gyrus': '6.2', 'Lamp5-lhx6 and chandelier': '10.2', 'Lower rhombic lip': '1.7', 'Mammillary body': '4.6', 'Medium spiny neuron': '6.6', 'Mge interneuron': '4.3', 'Midbrain-derived inhibitory': '4.6', 'Miscellaneous': '8.6', 'Splatter': '3.5', 'Thalamic excitatory': '3.8', 'Upper rhombic lip': '1.9', 'Upper-layer intratelencephalic': '6.9', 'Astrocyte': '3.9', 'Bergmann glia': '3.0', 'Central nervous system macrophage': '12.5', 'Choroid plexus epithelial cell': '0.4', 'Committed oligodendrocyte precursor': '19.7', 'Ependymal cell': '2.5', 'Oligodendrocyte': '22.7', 'Oligodendrocyte precursor cell': '8.9', 'Endothelial cell': '15.5', 'Pericyte': '7.4', 'Vascular associated smooth muscle cell': '3.6', 'Fibroblast': '5.0', 'Leukocyte': '8.1', 'Basophil': '2.8', 'Eosinophil': '1.7', 'Neutrophil': '5.5', 'Classical monocyte': '11.9', 'Non-classical monocyte': '31.6', 'Intermediate monocyte': '41.0', 'T-reg': '16.3', 'GdT-cell': '5.3', 'MAIT T-cell': '31.3', 'Memory CD4 T-cell': '6.3', 'Naive CD4 T-cell': '8.6', 'Memory CD8 T-cell': '3.8', 'Naive CD8 T-cell': '7.5', 'Memory B-cell': '0.9', 'Naive B-cell': '0.8', 'Plasmacytoid DC': '19.3', 'Myeloid DC': '30.0', 'NK-cell': '7.7', 'Total PBMC': '19.1', 'Vd2 gdTCR': '18.0', 'Memory CD4 T-cell Th1\\/Th17': '10.9', 'Memory CD4 T-cell Th17': '11.4', 'Memory CD4 T-cell Th2': '8.9', 'Non-Vd2 gdTCR': '12.1', 'Memory CD4 T-cell Th1': '9.6', 'Memory CD4 T-cell TFH': '11.6', 'Terminal effector memory CD4 T-cell': '16.4', 'Central memory CD8 T-cell': '13.9', 'Effector memory CD8 T-cell': '14.3', 'Terminal effector memory CD8 T-cell': '11.3', 'Non-switched memory B-cell': '3.9', 'Plasmablast': '7.4', 'Switched memory B-cell': '4.2', 'Exhausted memory B-cell': '4.1', 'Progenitor cell': '8.2', 'Memory T-reg': '10.5', 'Naive CD4 T-cell activated': '21.8', 'Naive CD8 T-cell activated': '23.4', 'Naive T-reg': '10.4'}
|
4Y2E
|
{'Adipose Tissue': 14.678740033222592, 'Adrenal Gland': 8.670054263565891, 'Bladder': 13.924428571428573, 'Blood': 7.695739935414424, 'Blood Vessel': 30.040554307116103, 'Brain': 12.733590007570024, 'Breast': 13.464479302832244, 'Cervix Uteri': 26.521052631578947, 'Colon': 8.753534017971758, 'Esophagus': 29.588318339100347, 'Fallopian Tube': 14.630555555555556, 'Heart': 10.33308362369338, 'Kidney': 7.118696629213483, 'Liver': 2.391061504424779, 'Lung': 32.78631487889274, 'Muscle': 11.31385305105853, 'Nerve': 17.89908239095315, 'Ovary': 11.948511111111111, 'Pancreas': 2.892417987804878, 'Pituitary': 8.891409893992932, 'Prostate': 14.648983673469388, 'Salivary Gland': 12.939407407407408, 'Skin': 47.06272249861802, 'Small Intestine': 8.802080213903743, 'Spleen': 29.18489626556017, 'Stomach': 7.904200557103064, 'Testis': 18.32682271468144, 'Thyroid': 13.071820826952528, 'Uterus': 21.598211267605635, 'Vagina': 54.175865384615385}
|
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[46.45, 38.55, 43.78, 40.93, 41.16, 45.09, 37.36, 61.75, 49.34, 43.08, 40.12, 43.15, 48.26, 41.47, 44.35, 39.38, 40.39, 39.77, 41.18, 38.28, 42.09, 43.93, 42.0, 41.42, 41.57, 42.71, 43.78, 41.38, 46.69, 45.73, 43.09, 44.78, 43.15, 42.89, 41.86, 42.68, 40.7, 38.48, 36.11, 35.62, 32.28, 29.76, 31.04, 27.92, 31.19, 31.11, 37.93, 34.91, 40.59, 53.48, 66.68, 75.84, 88.8, 92.17, 94.46, 94.26, 92.9, 93.5, 94.53, 94.32, 91.74, 91.35, 91.1, 89.21, 87.05, 78.88, 66.17, 61.96, 65.79, 71.17, 82.77, 91.26, 92.58, 94.18, 94.38, 93.4, 91.34, 89.0, 84.39, 84.55, 79.26, 83.09, 87.57, 84.18, 78.82, 84.43, 90.0, 91.89, 88.52, 87.54, 92.47, 92.21, 92.13, 87.81, 74.56, 77.09, 72.0, 70.73, 72.4, 75.98, 74.64, 75.5, 78.04, 78.73, 76.36, 74.66, 71.42, 72.54, 77.09, 82.07, 82.3, 82.62, 81.01, 83.17, 84.31, 76.48, 79.37, 82.24, 84.46, 87.48, 86.93, 85.71, 85.51, 89.29, 87.26, 86.03, 85.98, 85.65, 86.35, 86.5, 88.93, 92.39, 94.08, 95.03, 94.91, 94.09, 90.5, 86.24, 86.54, 83.29, 74.54, 71.26, 67.7, 63.04, 59.99, 56.03, 53.98, 54.86, 55.74, 59.04, 69.29, 80.14, 82.47, 88.22, 87.36, 85.85, 88.91, 89.72, 87.27, 86.99, 89.9, 89.21, 87.34, 86.52, 88.02, 90.12, 92.53, 93.56, 94.81, 94.16, 94.84, 92.34, 86.09, 91.42, 91.49, 86.39, 86.77, 89.81, 87.59, 80.67, 86.5, 88.05, 83.15, 84.85, 87.03, 85.92, 83.31, 75.84, 60.96, 48.4, 34.86, 33.28, 34.95, 31.82, 31.9, 33.47, 32.66, 38.06, 34.15, 43.43, 44.96, 34.29, 34.62, 48.25, 41.03, 40.61, 53.47, 45.33, 42.38, 44.31, 51.05, 45.61, 43.03, 46.37, 40.85, 40.85, 48.87, 43.84, 45.67, 42.55, 47.46, 42.42, 47.96, 41.63, 41.48, 41.71, 33.85, 43.41, 39.19, 48.14, 38.68, 48.71, 42.99, 37.33, 41.18, 37.2, 36.25, 35.44, 31.08, 35.26, 46.5, 50.3, 61.67, 73.11, 91.28, 94.36, 97.42, 98.09, 97.89, 97.84, 98.38, 98.71, 98.63, 98.22, 94.07, 90.89, 90.36, 89.75, 91.88, 94.1, 93.01, 92.16, 94.45, 93.2, 90.86, 95.81, 95.22, 94.7, 95.45, 96.63, 98.03, 97.88, 98.64, 98.54, 98.8, 98.46, 98.44, 91.89, 87.31, 86.66, 88.75, 92.86, 96.35, 93.69, 94.76, 91.73, 88.13, 79.26, 82.45, 89.94, 97.27, 97.79, 98.19, 98.33, 98.39, 98.42, 95.93, 91.15, 83.99, 85.67, 79.15, 74.26, 79.25, 84.44, 93.96, 97.39, 97.47, 97.82, 98.52, 98.59, 98.15, 98.25, 98.78, 98.7, 98.67, 98.81, 98.83, 98.55, 98.56, 98.51, 98.35, 98.0, 98.0, 98.0, 98.12, 98.4, 98.8, 98.69, 98.79, 97.61, 94.04, 87.49, 83.81, 92.03, 90.08, 93.2, 97.98, 98.28, 98.27, 98.62, 98.84, 98.81, 98.76, 98.76, 98.8, 98.62, 98.48, 97.87, 97.56, 96.76, 95.86, 96.3, 96.96, 97.63, 95.46, 96.76, 97.98, 96.99, 96.08, 97.14, 96.97, 93.06, 93.62, 93.13, 87.95, 86.86, 82.87, 89.33, 88.8, 91.11, 84.64, 86.93, 87.19, 95.94, 95.97, 92.12, 97.68, 98.12, 96.65, 95.94, 97.7, 97.43, 95.53, 95.5, 95.22, 89.18, 81.96, 70.03, 64.0, 57.59, 53.92, 54.61, 43.04, 42.45, 38.85, 44.5, 45.1, 45.18, 51.29, 58.01, 62.75, 62.64, 57.04, 58.75, 61.2, 63.45, 47.24, 58.95, 58.52, 59.27, 66.19, 60.15, 50.44, 51.42, 49.09, 43.86, 35.63, 38.51, 41.0]
|
[1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.95, 1.0, 0.93, 1.0, 0.91, 1.0, 0.94, 1.0, 0.96, 0.86, 0.95, 0.89, 0.85, 0.96, 0.68, 0.85, 0.14, 0.24, 0.47, 0.25, 0.31, 0.0, 0.4, 0.25, 0.0, 0.18, 0.63, 0.21, 0.12, 0.64, 0.78, 0.72, 0.72, 0.13, 0.64, 0.3, 0.03, 0.04, 0.01, 0.0, 0.0, 0.18, 0.05, 0.56, 0.42, 0.75, 0.27, 0.13, 0.54, 0.37, 0.03, 0.16, 0.0, 0.39, 0.61, 0.09, 0.03, 0.05, 0.02, 0.29, 0.19, 0.55, 0.59, 0.83, 0.22, 0.19, 0.74, 0.53, 0.06, 0.54, 0.76, 0.48, 0.68, 0.04, 0.45, 0.03, 0.59, 0.48, 0.06, 0.06, 0.61, 0.5, 0.68, 0.49, 0.21, 0.41, 0.51, 0.57, 0.07, 0.57, 0.7, 0.3, 0.11, 0.79, 0.82, 0.06, 0.22, 0.0, 0.0, 0.0, 0.0, 0.24, 0.35, 0.63, 0.23, 0.51, 0.72, 0.29, 0.68, 0.56, 0.62, 0.91, 0.92, 0.62, 0.8, 0.45, 0.47, 0.32, 0.06, 0.1, 0.2, 0.01, 0.02, 0.42, 0.24, 0.01, 0.46, 0.64, 0.42, 0.64, 0.11, 0.56, 0.03, 0.26, 0.06, 0.01, 0.32, 0.12, 0.0, 0.03, 0.33, 0.31, 0.0, 0.16, 0.28, 0.45, 0.18, 0.45, 0.71, 0.15, 0.09, 0.44, 0.3, 0.56, 0.48, 0.81, 0.82, 0.98, 0.93, 0.94, 1.0, 0.98, 0.99, 0.96, 0.91, 0.97, 0.94, 0.96, 0.86, 0.99, 0.81, 0.82, 0.91, 0.76, 0.74, 0.88, 0.92, 0.8, 0.97, 0.96, 0.98, 1.0, 1.0, 0.99, 0.98, 0.98, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 0.99, 0.99, 1.0, 0.9, 0.95, 0.91, 0.86, 0.84, 0.68, 0.54, 0.48, 0.61, 0.35, 0.04, 0.07, 0.47, 0.03, 0.15, 0.7, 0.38, 0.0, 0.07, 0.0, 0.0, 0.16, 0.19, 0.46, 0.08, 0.07, 0.56, 0.38, 0.52, 0.78, 0.19, 0.0, 0.69, 0.85, 0.33, 0.4, 0.03, 0.53, 0.07, 0.0, 0.0, 0.0, 0.0, 0.0, 0.47, 0.93, 0.25, 0.77, 0.16, 0.56, 0.2, 0.48, 0.97, 0.71, 0.81, 0.76, 0.17, 0.39, 0.13, 0.27, 0.41, 0.0, 0.52, 0.05, 0.38, 0.4, 0.48, 0.71, 0.82, 0.29, 0.43, 0.0, 0.29, 0.7, 0.28, 0.02, 0.65, 0.43, 0.0, 0.04, 0.59, 0.04, 0.0, 0.27, 0.4, 0.0, 0.21, 0.74, 0.62, 0.69, 0.16, 0.01, 0.0, 0.0, 0.0, 0.01, 0.02, 0.37, 0.32, 0.0, 0.17, 0.06, 0.07, 0.0, 0.0, 0.0, 0.02, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.43, 0.51, 0.45, 0.68, 0.22, 0.07, 0.04, 0.55, 0.47, 0.0, 0.24, 0.48, 0.24, 0.0, 0.35, 0.72, 0.37, 0.04, 0.42, 0.26, 0.02, 0.45, 0.13, 0.2, 0.75, 0.26, 0.0, 0.27, 0.32, 0.09, 0.0, 0.4, 0.47, 0.12, 0.1, 0.65, 0.74, 0.33, 0.75, 0.21, 0.66, 0.06, 0.72, 0.72, 0.6, 0.75, 0.75, 0.55, 0.97, 0.89, 0.72, 0.61, 0.6, 0.52, 0.58, 0.66, 0.37, 0.93, 0.93, 0.57, 0.94, 0.5, 0.65, 0.52, 0.53, 0.58, 0.79, 0.91, 0.86, 0.92, 0.89, 0.97]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 74.365274
| 0.496301
| 1,889
|
O43791
|
Q27J81
|
28448495
|
UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
INF2
|
MSVKEGAQRKWAALKEKLGPQDSDPTEANLESADPELCIRLLQMPSVVNYSGLRKRLEGSDGGWMVQFLEQSGLDLLLEALARLSGRGVARISDALLQLTCVSCVRAVMNSRQGIEYILSNQGYVRQLSQALDTSNVMVKKQVFELLAALCIYSPEGHVLTLDALDHYKTVCSQQYRFSIVMNELSGSDNVPYVVTLLSVINAVILGPEDLRARTQLRNEFIGLQLLDVLARLRDLEDADLLIQLEAFEEAKAEDEEELLRVSGGVDMSSHQEVFASLFHKVSCSPVSAQLLSVLQGLLHLEPTLRSSQLLWEALESLVNRAVLLASDAQECTLEEVVERLLSVKGRPRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEVIVAQVDHGLGSAWVPSHRRVNPPTLRMKKLNWQKLPSNVAREHNSMWASLSSPDAEAVEPDFSSIERLFSFPAAKPKEPTMVAPRARKEPKEITFLDAKKSLNLNIFLKQFKCSNEEVAAMIRAGDTTKFDVEVLKQLLKLLPEKHEIENLRAFTEERAKLASADHFYLLLLAIPCYQLRIECMLLCEGAAAVLDMVRPKAQLVLAACESLLTSRQLPIFCQLILRIGNFLNYGSHTGDADGFKISTLLKLTETKSQQNRVTLLHHVLEEAEKSHPDLLQLPRDLEQPSQAAGINLEIIRSEASSNLKKLLETERKVSASVAEVQEQYTERLQASISAFRALDELFEAIEQKQRELADYLCEDAQQLSLEDTFSTMKAFRDLFLRALKENKDRKEQAAKAERRKQQLAEEEARRPRGEDGKPVRKGPGKQEEVCVIDALLADIRKGFQLRKTARGRGDTDGGSKAASMDPPRATEPVATSNPAGDPVGSTRCPASEPGLDATTASESRGWDLVDAVTPGPQPTLEQLEEGGPRPLERRSSWYVDASDVLTTEDPQCPQPLEGAWPVTLGDAQALKPLKFSSNQPPAAGSSRQDAKDPTSLLGVLQAEADSTSEGLEDAVHSRGARPPAAGPGGDEDEDEEDTAPESALDTSLDKSFSEDAVTDSSGSGTLPRARGRASKGTGKRRKKRPSRSQEEVPPDSDDNKTKKLCVIQ
|
Homo sapiens
|
Cytoplasm, perinuclear region
|
Low tissue specificity
|
{'Ciliated cells': '10.2', 'Basal respiratory cells': '19.5', 'Club cells': '18.6', 'Ionocytes': '31.7', 'Mucus glandular cells': '20.1', 'Serous glandular cells': '5.7', 'Gastric mucus-secreting cells': '177.5', 'Proximal enterocytes': '83.1', 'Paneth cells': '66.1', 'Distal enterocytes': '163.7', 'Intestinal goblet cells': '74.3', 'Exocrine glandular cells': '-0.643', 'Basal prostatic cells': '6.8', 'Prostatic glandular cells': '6.9', 'Breast glandular cells': '-0.207', 'Breast myoepithelial cells': '-0.233', 'Glandular and luminal cells': '17.6', 'Secretory cells': '8.5', 'Basal keratinocytes': '26.1', 'Suprabasal keratinocytes': '23.4', 'Basal squamous epithelial cells': '13.1', 'Squamous epithelial cells': '7.7', 'Alveolar cells type 1': '0.297', 'Alveolar cells type 2': '-0.329', 'Salivary duct cells': '13.0', 'Ductal cells': '0.572', 'Hepatocytes': '0.061', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.188', 'Distal tubular cells': '6.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.272', 'Sertoli cells': '0.639', 'Granulosa cells': '1.2', 'Enteroendocrine cells': '24.3', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '0.244', 'Excitatory neurons': '16.1', 'Inhibitory neurons': '1.8', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.5', 'Bipolar cells': '0.8', 'Horizontal cells': '1.3', 'Astrocytes': '9.6', 'Oligodendrocyte precursor cells': '10.4', 'Oligodendrocytes': '83.5', 'Microglial cells': '19.7', 'Muller glia cells': '48.3', 'Schwann cells': '0.044', 'Spermatogonia': '0.185', 'Spermatocytes': '-0.074', 'Early spermatids': '-0.509', 'Late spermatids': '-0.454', 'Oocytes': '5.1', 'Cytotrophoblasts': '54.5', 'Syncytiotrophoblasts': '27.0', 'Extravillous trophoblasts': '93.2', 'Endothelial cells': '28.6', 'Lymphatic endothelial cells': '37.3', 'Cardiomyocytes': '0.289', 'Skeletal myocytes': '-0.083', 'Smooth muscle cells': '39.9', 'Adipocytes': '48.3', 'Melanocytes': '0.004', 'Fibroblasts': '17.0', 'Peritubular cells': '0.341', 'Endometrial stromal cells': '8.5', 'Ovarian stromal cells': '4.8', 'Undifferentiated cells': '31.2', 'T-cells': '9.2', 'B-cells': '22.9', 'Plasma cells': '10.3', 'Nk-cells': '2.0', 'Granulocytes': '4.9', 'Monocytes': '3.9', 'Macrophages': '21.1', 'Hofbauer cells': '29.5', 'Kupffer cells': '23.8', 'Dendritic cells': '27.5', 'Langerhans cells': '0.109', 'Erythroid cells': '0.035', 'Adipocytes (Subcutaneous)': '0.207', 'Adipocytes (Visceral)': '0.074', 'Breast glandular cells (progenitors)': '-0.383', 'Adipocytes (Breast)': '0.410', 'Colon enterocytes': '0.039', 'Colon enteroendocrine cells': '0.210', 'Enteric glia cells': '0.610', 'Mitotic cells (Colon)': '0.041', 'Mitotic cells (Heart)': '0.472', 'Podocytes': '0.207', 'Ascending Loop of Henle cells': '0.209', 'Intercalated cells': '0.018', 'Cholangiocyte': '0.311', 'NK-cells (Liver)': '-0.197', 'Respiratory ciliated cells': '-0.019', 'Mitotic cells (Lung)': '-0.053', 'NK-cells (Lung)': '0.320', 'B-cells (Lung)': '0.022', 'Alpha cells': '0.412', 'Beta cells': '0.217', 'Prostate glandular cells': '-0.416', 'Prostate basal glandular cells': '-0.162', 'Urothelial cells': '0.038', 'Keratinocyte (other)': '0.008', 'Keratinocyte (granular)': '-0.195', 'Hair cortex cells': '0.010', 'Inner root sheath cells': '0.034', 'Outer root sheath cells': '0.243', 'Sebaceous gland cells': '-0.039', 'Eccrine sweat gland cells': '-0.071', 'Adipocytes (Skin)': '-0.042', 'Mitotic cells (Skin)': '0.191', 'Parietal cells': '0.015', 'Chief cells': '-0.053', 'Gastric mucous cells': '0.595', 'Gastric enteroendocrine cells': '0.149', 'Mitotic cells (Stomach)': '0.485', 'Parafollicular cells': '-0.068', 'Thyroid glandular cells': '0.006', 'Mitotic cells (Thyroid)': '0.159', 'Adrenal cortex cells': '0.162', 'Adrenal medulla cells': '-0.032', 'Mitotic cells (Adrenal gland)': '0.174', 'Minor salivary glandular cells': '0.530', 'Minor salivary gland ductal cells': '0.091', 'Minor salivary gland basal cells': '0.302', 'Mitotic cells (Minor salivary gland)': '0.380', 'Adipocytes (Minor salivary gland)': '0.305', 'Somatotropes': '-0.341', 'Lactotropes': '-0.397', 'Gonadotropes': '-0.022', 'Corticotropes': '-0.303', 'Thyrotropes': '-0.098', 'Undifferentiated cells (Pituitary gland)': '0.530', 'Mitotic cells (Spleen)': '-0.351', 'Platelets': '-0.145', 'Erythrocytes': '0.005', 'Hematopoietic stem cells': '-0.272', 'B-cells (Spleen)': '0.209', 'NK-cells (Spleen)': '0.235', 'Amygdala excitatory': '17.1', 'Cerebellar inhibitory': '1.2', 'Cge interneuron': '5.5', 'Deep-layer corticothalamic and 6b': '33.4', 'Deep-layer intratelencephalic': '29.7', 'Deep-layer near-projecting': '19.7', 'Eccentric medium spiny neuron': '30.2', 'Hippocampal ca1-3': '13.3', 'Hippocampal ca4': '28.1', 'Hippocampal dentate gyrus': '4.3', 'Lamp5-lhx6 and chandelier': '2.2', 'Lower rhombic lip': '7.4', 'Mammillary body': '16.5', 'Medium spiny neuron': '51.5', 'Mge interneuron': '4.6', 'Midbrain-derived inhibitory': '1.5', 'Miscellaneous': '25.9', 'Splatter': '6.9', 'Thalamic excitatory': '6.7', 'Upper rhombic lip': '6.7', 'Upper-layer intratelencephalic': '25.3', 'Astrocyte': '21.4', 'Bergmann glia': '9.0', 'Central nervous system macrophage': '13.1', 'Choroid plexus epithelial cell': '23.9', 'Committed oligodendrocyte precursor': '79.9', 'Ependymal cell': '7.8', 'Oligodendrocyte': '154.0', 'Oligodendrocyte precursor cell': '31.7', 'Endothelial cell': '41.1', 'Pericyte': '95.2', 'Vascular associated smooth muscle cell': '125.5', 'Fibroblast': '59.7', 'Leukocyte': '14.3', 'Basophil': '1.9', 'Eosinophil': '0.1', 'Neutrophil': '1.3', 'Classical monocyte': '6.1', 'Non-classical monocyte': '0.2', 'Intermediate monocyte': '1.8', 'T-reg': '12.1', 'GdT-cell': '0.9', 'MAIT T-cell': '2.7', 'Memory CD4 T-cell': '3.2', 'Naive CD4 T-cell': '18.2', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '24.4', 'Memory B-cell': '1.6', 'Naive B-cell': '13.1', 'Plasmacytoid DC': '14.6', 'Myeloid DC': '9.4', 'NK-cell': '1.9', 'Total PBMC': '9.5', 'Vd2 gdTCR': '2.9', 'Memory CD4 T-cell TFH': '49.5', 'Memory CD4 T-cell Th2': '31.6', 'Memory CD4 T-cell Th17': '25.2', 'Memory CD4 T-cell Th1\\/Th17': '12.2', 'Non-Vd2 gdTCR': '3.5', 'Memory CD4 T-cell Th1': '28.1', 'Terminal effector memory CD4 T-cell': '3.4', 'Central memory CD8 T-cell': '9.1', 'Effector memory CD8 T-cell': '4.9', 'Terminal effector memory CD8 T-cell': '3.6', 'Switched memory B-cell': '13.9', 'Plasmablast': '9.5', 'Non-switched memory B-cell': '10.2', 'Exhausted memory B-cell': '6.3', 'Progenitor cell': '6.1', 'Naive CD4 T-cell activated': '11.7', 'Naive CD8 T-cell activated': '9.2', 'Memory T-reg': '44.9', 'Naive T-reg': '35.7'}
|
8RV2, 9AZ4, 9AZP, 9AZQ, 9B03, 9B0K
|
{'Adipose Tissue': 63.36367109634551, 'Adrenal Gland': 23.676267441860464, 'Bladder': 46.01714285714286, 'Blood': 8.687929924650161, 'Blood Vessel': 81.0963520599251, 'Brain': 28.56090764572294, 'Breast': 55.32324618736384, 'Cervix Uteri': 49.68052631578948, 'Colon': 47.30630295250321, 'Esophagus': 36.35361314878893, 'Fallopian Tube': 36.376666666666665, 'Heart': 15.107116144018583, 'Kidney': 29.16370786516854, 'Liver': 24.67438053097345, 'Lung': 58.5331660899654, 'Muscle': 10.235414694894148, 'Nerve': 209.57788368336023, 'Ovary': 23.97431666666667, 'Pancreas': 9.20311280487805, 'Pituitary': 13.380095406360423, 'Prostate': 38.208938775510205, 'Salivary Gland': 21.127271604938272, 'Skin': 39.57898839137645, 'Small Intestine': 44.37208556149733, 'Spleen': 54.03199170124481, 'Stomach': 39.79473537604456, 'Testis': 67.90271468144044, 'Thyroid': 37.12271975497703, 'Uterus': 48.76605633802816, 'Vagina': 47.58596153846154}
|
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0.03, 0.32, 0.77, 0.39, 0.0, 0.47, 0.52, 0.1, 0.03, 0.5, 0.18, 0.01, 0.51, 0.47, 0.01, 0.28, 0.66, 0.13, 0.03, 0.59, 0.34, 0.0, 0.25, 0.46, 0.24, 0.21, 0.38, 0.34, 0.0, 0.0, 0.73, 0.4, 0.12, 0.78, 0.3, 0.53, 0.41, 0.92, 0.78, 0.09, 0.36, 0.08, 0.35, 0.62, 0.08, 0.01, 0.39, 0.19, 0.01, 0.4, 0.37, 0.01, 0.17, 0.44, 0.27, 0.03, 0.43, 0.61, 0.04, 0.25, 0.63, 0.4, 0.03, 0.57, 0.4, 0.28, 0.39, 0.56, 0.43, 0.54, 0.38, 0.4, 0.18, 0.57, 0.65, 0.28, 0.7, 0.53, 0.66, 0.48, 0.52, 0.52, 0.48, 0.73, 0.74, 0.73, 0.65, 0.92, 0.95, 0.79, 0.99, 0.91, 0.89, 0.87, 0.91, 0.85, 0.96, 0.93, 1.0, 1.0, 0.9, 0.77, 0.85, 0.89, 0.65, 0.61, 0.47, 0.18, 0.0, 0.34, 0.44, 0.15, 0.06, 0.31, 0.4, 0.06, 0.46, 0.66, 0.13, 0.41, 0.77, 0.4, 0.68, 0.8, 0.63, 0.91, 0.96, 0.87, 0.84, 0.91, 0.98, 0.76, 0.96, 0.97, 0.85, 0.97, 0.96, 0.92, 0.98, 0.92, 0.93, 0.97, 0.96, 0.92, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 1.0, 1.0, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.99, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.96, 1.0, 0.9, 1.0, 0.8, 0.99, 1.0, 1.0, 0.99, 1.0, 0.99, 0.89, 0.99, 0.93, 0.96, 0.95, 0.92, 0.93, 0.92, 0.68, 0.76, 0.83, 0.83, 0.82, 0.8, 0.68, 0.8, 0.63, 0.87, 0.94, 0.87, 0.95, 0.9, 0.9, 0.81, 0.89, 0.95, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.95, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.97, 0.96, 0.97, 0.91, 0.97, 0.96, 0.99, 0.97, 0.89, 1.0, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.55, 0.52, 0.36, 0.58, 0.82, 0.9, 1.0, 0.99, 0.98, 0.76, 0.67, 0.82, 0.38, 0.99, 0.99, 1.0, 1.0, 1.0, 0.9, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 1.0, 0.82, 1.0, 0.86, 1.0, 0.96, 1.0, 1.0, 0.89, 0.97, 0.81, 0.97, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.96, 1.0, 0.94, 0.96, 0.97, 0.95, 1.0, 0.99, 0.99, 0.93, 0.97, 0.98, 0.98, 0.99, 1.0, 1.0, 0.76, 1.0, 0.52, 0.72, 0.66, 0.38, 0.78, 0.63, 0.94, 0.95, 1.0, 0.91, 1.0, 1.0, 0.99, 0.83, 0.78, 0.82, 0.41, 0.6, 0.91, 0.87, 0.92, 1.0, 0.9, 0.9, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 66.449231
| 0.603483
| 309
|
O43791
|
Q49A26
|
25278611
|
UbiNet, UbiBrowser, DegPred
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
GLYR1
|
MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLKICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYIH
|
Homo sapiens
|
Nucleus, Chromosome
|
Low tissue specificity
|
{'Ciliated cells': '51.3', 'Basal respiratory cells': '16.7', 'Club cells': '27.1', 'Ionocytes': '26.9', 'Mucus glandular cells': '35.8', 'Serous glandular cells': '28.5', 'Gastric mucus-secreting cells': '28.9', 'Proximal enterocytes': '37.0', 'Paneth cells': '32.3', 'Distal enterocytes': '49.4', 'Intestinal goblet cells': '42.3', 'Exocrine glandular cells': '-0.688', 'Basal prostatic cells': '39.6', 'Prostatic glandular cells': '43.3', 'Breast glandular cells': '0.520', 'Breast myoepithelial cells': '0.437', 'Glandular and luminal cells': '42.7', 'Secretory cells': '26.5', 'Basal keratinocytes': '25.7', 'Suprabasal keratinocytes': '29.5', 'Basal squamous epithelial cells': '18.2', 'Squamous epithelial cells': '24.0', 'Alveolar cells type 1': '0.108', 'Alveolar cells type 2': '0.190', 'Salivary duct cells': '26.9', 'Ductal cells': '0.708', 'Hepatocytes': '0.510', 'Cholangiocytes': '28.6', 'Proximal tubular cells': '0.245', 'Distal tubular cells': '55.3', 'Collecting duct cells': '33.1', 'Mesothelial cells': '0.201', 'Sertoli cells': '0.413', 'Granulosa cells': '16.8', 'Enteroendocrine cells': '46.1', 'Pancreatic endocrine cells': '22.1', 'Leydig cells': '0.387', 'Excitatory neurons': '42.1', 'Inhibitory neurons': '35.4', 'Cone photoreceptor cells': '42.5', 'Rod photoreceptor cells': '33.5', 'Bipolar cells': '30.5', 'Horizontal cells': '32.1', 'Astrocytes': '33.8', 'Oligodendrocyte precursor cells': '26.9', 'Oligodendrocytes': '33.4', 'Microglial cells': '31.3', 'Muller glia cells': '23.1', 'Schwann cells': '0.096', 'Spermatogonia': '0.640', 'Spermatocytes': '0.530', 'Early spermatids': '-0.118', 'Late spermatids': '-0.457', 'Oocytes': '7.4', 'Cytotrophoblasts': '27.8', 'Syncytiotrophoblasts': '33.9', 'Extravillous trophoblasts': '30.7', 'Endothelial cells': '30.2', 'Lymphatic endothelial cells': '22.8', 'Cardiomyocytes': '0.703', 'Skeletal myocytes': '-0.303', 'Smooth muscle cells': '26.6', 'Adipocytes': '24.7', 'Melanocytes': '0.190', 'Fibroblasts': '23.2', 'Peritubular cells': '0.341', 'Endometrial stromal cells': '34.4', 'Ovarian stromal cells': '14.5', 'Undifferentiated cells': '34.4', 'T-cells': '26.0', 'B-cells': '26.0', 'Plasma cells': '30.4', 'Nk-cells': '27.6', 'Granulocytes': '34.4', 'Monocytes': '34.9', 'Macrophages': '38.3', 'Hofbauer cells': '31.5', 'Kupffer cells': '49.4', 'Dendritic cells': '32.8', 'Langerhans cells': '0.261', 'Erythroid cells': '-0.151', 'Adipocytes (Subcutaneous)': '-0.030', 'Adipocytes (Visceral)': '-0.074', 'Breast glandular cells (progenitors)': '0.358', 'Adipocytes (Breast)': '-0.376', 'Colon enterocytes': '-0.148', 'Colon enteroendocrine cells': '0.168', 'Enteric glia cells': '-0.244', 'Mitotic cells (Colon)': '-0.174', 'Mitotic cells (Heart)': '0.449', 'Podocytes': '-0.102', 'Ascending Loop of Henle cells': '0.501', 'Intercalated cells': '0.062', 'Cholangiocyte': '0.262', 'NK-cells (Liver)': '-0.319', 'Respiratory ciliated cells': '0.067', 'Mitotic cells (Lung)': '0.109', 'NK-cells (Lung)': '-0.036', 'B-cells (Lung)': '-0.201', 'Alpha cells': '0.468', 'Beta cells': '0.301', 'Prostate glandular cells': '0.227', 'Prostate basal glandular cells': '0.255', 'Urothelial cells': '0.013', 'Keratinocyte (other)': '0.365', 'Keratinocyte (granular)': '-0.032', 'Hair cortex cells': '-0.022', 'Inner root sheath cells': '0.033', 'Outer root sheath cells': '0.156', 'Sebaceous gland cells': '0.010', 'Eccrine sweat gland cells': '-0.131', 'Adipocytes (Skin)': '-0.216', 'Mitotic cells (Skin)': '0.350', 'Parietal cells': '-0.582', 'Chief cells': '-0.531', 'Gastric mucous cells': '-0.303', 'Gastric enteroendocrine cells': '-0.434', 'Mitotic cells (Stomach)': '0.137', 'Parafollicular cells': '0.142', 'Thyroid glandular cells': '0.514', 'Mitotic cells (Thyroid)': '-0.096', 'Adrenal cortex cells': '0.410', 'Adrenal medulla cells': '0.008', 'Mitotic cells (Adrenal gland)': '0.203', 'Minor salivary glandular cells': '0.544', 'Minor salivary gland ductal cells': '0.156', 'Minor salivary gland basal cells': '0.258', 'Mitotic cells (Minor salivary gland)': '0.301', 'Adipocytes (Minor salivary gland)': '0.056', 'Somatotropes': '0.087', 'Lactotropes': '-0.010', 'Gonadotropes': '0.101', 'Corticotropes': '-0.080', 'Thyrotropes': '0.109', 'Undifferentiated cells (Pituitary gland)': '0.230', 'Mitotic cells (Spleen)': '-0.140', 'Platelets': '-0.020', 'Erythrocytes': '-0.101', 'Hematopoietic stem cells': '-0.211', 'B-cells (Spleen)': '0.389', 'NK-cells (Spleen)': '0.304', 'Amygdala excitatory': '77.3', 'Cerebellar inhibitory': '59.9', 'Cge interneuron': '60.5', 'Deep-layer corticothalamic and 6b': '64.9', 'Deep-layer intratelencephalic': '71.0', 'Deep-layer near-projecting': '67.1', 'Eccentric medium spiny neuron': '60.6', 'Hippocampal ca1-3': '70.4', 'Hippocampal ca4': '57.2', 'Hippocampal dentate gyrus': '74.3', 'Lamp5-lhx6 and chandelier': '52.9', 'Lower rhombic lip': '44.9', 'Mammillary body': '61.6', 'Medium spiny neuron': '62.2', 'Mge interneuron': '59.2', 'Midbrain-derived inhibitory': '65.6', 'Miscellaneous': '70.1', 'Splatter': '58.4', 'Thalamic excitatory': '59.8', 'Upper rhombic lip': '56.0', 'Upper-layer intratelencephalic': '81.2', 'Astrocyte': '68.8', 'Bergmann glia': '44.3', 'Central nervous system macrophage': '81.8', 'Choroid plexus epithelial cell': '103.2', 'Committed oligodendrocyte precursor': '63.9', 'Ependymal cell': '102.4', 'Oligodendrocyte': '62.0', 'Oligodendrocyte precursor cell': '56.3', 'Endothelial cell': '87.8', 'Pericyte': '58.8', 'Vascular associated smooth muscle cell': '58.5', 'Fibroblast': '64.6', 'Leukocyte': '70.2', 'Basophil': '70.1', 'Eosinophil': '7.8', 'Neutrophil': '100.0', 'Classical monocyte': '72.8', 'Non-classical monocyte': '92.9', 'Intermediate monocyte': '75.1', 'T-reg': '42.7', 'GdT-cell': '9.0', 'MAIT T-cell': '44.7', 'Memory CD4 T-cell': '6.0', 'Naive CD4 T-cell': '68.4', 'Memory CD8 T-cell': '8.9', 'Naive CD8 T-cell': '63.1', 'Memory B-cell': '6.2', 'Naive B-cell': '60.2', 'Plasmacytoid DC': '64.0', 'Myeloid DC': '75.0', 'NK-cell': '81.0', 'Total PBMC': '46.4', 'Vd2 gdTCR': '42.7', 'Memory CD4 T-cell Th1\\/Th17': '63.8', 'Memory CD4 T-cell Th17': '71.2', 'Memory CD4 T-cell Th2': '74.6', 'Non-Vd2 gdTCR': '52.9', 'Memory CD4 T-cell Th1': '75.3', 'Memory CD4 T-cell TFH': '92.9', 'Terminal effector memory CD4 T-cell': '48.2', 'Central memory CD8 T-cell': '50.8', 'Effector memory CD8 T-cell': '48.1', 'Terminal effector memory CD8 T-cell': '45.9', 'Non-switched memory B-cell': '57.3', 'Plasmablast': '60.0', 'Switched memory B-cell': '60.3', 'Exhausted memory B-cell': '56.2', 'Progenitor cell': '52.6', 'Memory T-reg': '95.6', 'Naive CD4 T-cell activated': '97.2', 'Naive CD8 T-cell activated': '105.7', 'Naive T-reg': '84.6'}
|
2UYY, 4GUR, 4GUS, 4GUT, 4GUU, 4HSU, 6R1U, 6R25
|
{'Adipose Tissue': 47.63068106312293, 'Adrenal Gland': 50.40178294573643, 'Bladder': 70.5352380952381, 'Blood': 36.78548977395049, 'Blood Vessel': 60.771722846441946, 'Brain': 45.80345912187737, 'Breast': 52.02507625272331, 'Cervix Uteri': 66.48368421052632, 'Colon': 69.02423620025674, 'Esophagus': 73.13601384083044, 'Fallopian Tube': 76.6, 'Heart': 29.25524274099884, 'Kidney': 39.80359550561798, 'Liver': 27.93020796460177, 'Lung': 61.10451557093425, 'Muscle': 38.98789539227895, 'Nerve': 62.80483037156705, 'Ovary': 58.05744444444444, 'Pancreas': 22.437902439024388, 'Pituitary': 69.2955477031802, 'Prostate': 65.43722448979592, 'Salivary Gland': 51.23259259259259, 'Skin': 58.85555002763958, 'Small Intestine': 60.795508021390376, 'Spleen': 61.07676348547718, 'Stomach': 54.874763231197775, 'Testis': 56.05576177285319, 'Thyroid': 72.08964777947932, 'Uterus': 68.36457746478874, 'Vagina': 58.02198717948718}
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[37.17, 39.9, 51.12, 62.99, 78.87, 88.24, 90.1, 89.99, 90.89, 93.47, 95.1, 95.53, 94.87, 93.14, 91.98, 86.28, 83.54, 83.2, 84.67, 88.51, 91.89, 94.46, 95.13, 95.05, 94.91, 95.31, 94.36, 91.26, 89.77, 86.36, 82.61, 82.47, 83.4, 81.91, 84.79, 83.33, 78.02, 68.77, 71.37, 86.12, 89.96, 93.17, 94.03, 94.03, 93.96, 93.94, 91.63, 85.59, 81.79, 80.5, 86.09, 91.25, 92.01, 92.46, 91.88, 90.99, 91.32, 89.96, 91.89, 93.39, 93.03, 94.07, 93.25, 91.59, 89.84, 90.96, 90.59, 89.76, 90.77, 89.4, 89.18, 88.16, 85.19, 82.84, 79.43, 84.64, 87.53, 86.14, 90.24, 90.28, 90.58, 91.55, 91.83, 91.22, 91.66, 91.57, 89.67, 89.13, 89.44, 88.62, 87.64, 86.34, 81.38, 74.83, 60.62, 56.64, 52.87, 47.84, 42.74, 40.07, 35.78, 35.32, 31.82, 31.1, 33.36, 35.55, 33.12, 41.16, 38.79, 35.3, 36.13, 36.46, 37.71, 37.35, 38.51, 37.88, 37.37, 35.9, 33.49, 42.46, 36.84, 38.64, 34.45, 37.11, 37.16, 34.39, 35.33, 35.98, 36.71, 33.47, 34.01, 38.45, 34.61, 37.82, 35.87, 36.76, 36.61, 35.59, 36.56, 34.15, 37.49, 33.07, 37.46, 36.19, 37.44, 34.5, 40.44, 39.14, 35.87, 36.29, 35.89, 37.36, 35.66, 37.96, 31.57, 38.09, 36.92, 36.55, 37.31, 39.96, 35.11, 37.0, 37.18, 35.11, 34.85, 36.47, 33.66, 35.89, 37.66, 34.1, 38.5, 34.4, 29.46, 50.34, 37.99, 33.14, 43.66, 32.61, 40.59, 32.11, 37.33, 33.12, 35.84, 37.44, 34.66, 38.0, 39.49, 35.15, 38.74, 34.9, 35.21, 33.21, 38.8, 33.02, 35.96, 41.08, 34.32, 40.52, 36.39, 34.13, 35.67, 28.88, 35.26, 37.48, 42.37, 35.51, 40.57, 39.7, 35.91, 38.94, 36.45, 37.94, 35.94, 34.77, 36.36, 39.85, 32.82, 33.32, 33.06, 31.18, 35.72, 32.28, 30.13, 36.32, 31.86, 36.05, 33.03, 37.54, 33.53, 41.51, 35.07, 39.59, 41.52, 40.01, 40.64, 40.72, 40.72, 39.9, 38.0, 34.2, 34.23, 33.56, 32.89, 31.83, 34.33, 35.2, 31.13, 32.17, 37.65, 34.36, 45.04, 42.65, 44.0, 43.92, 48.37, 37.54, 47.83, 38.26, 46.74, 48.59, 54.42, 69.52, 84.27, 93.1, 95.97, 96.79, 97.16, 97.94, 98.52, 98.79, 98.86, 98.89, 98.85, 98.39, 98.15, 96.66, 95.91, 97.82, 98.14, 97.93, 98.01, 98.55, 98.61, 97.79, 97.75, 98.13, 97.65, 95.87, 95.65, 96.16, 98.07, 98.26, 98.75, 98.82, 98.74, 98.73, 98.35, 95.93, 95.12, 94.61, 95.69, 95.7, 96.77, 95.73, 94.02, 97.08, 96.23, 94.26, 94.62, 96.01, 98.02, 98.24, 97.97, 97.9, 97.06, 98.53, 98.73, 98.69, 98.53, 98.78, 98.79, 98.39, 98.22, 98.73, 98.64, 98.84, 98.94, 98.92, 98.88, 98.63, 98.45, 96.97, 97.68, 98.38, 98.26, 98.17, 98.6, 98.52, 98.36, 98.59, 98.74, 98.45, 97.51, 96.63, 97.73, 98.38, 98.77, 98.47, 98.29, 98.22, 98.63, 96.99, 98.35, 95.23, 98.55, 98.8, 98.9, 98.92, 98.84, 98.85, 98.63, 98.7, 98.69, 98.68, 98.67, 98.49, 98.71, 98.47, 98.64, 98.59, 98.75, 98.75, 98.69, 98.54, 98.73, 98.53, 98.23, 98.23, 98.01, 98.58, 98.77, 98.87, 98.92, 98.84, 98.84, 98.75, 98.69, 98.19, 96.93, 97.57, 97.93, 97.23, 97.88, 98.34, 97.71, 96.92, 97.37, 97.84, 98.38, 98.48, 98.8, 98.71, 98.85, 98.82, 98.72, 98.58, 98.32, 98.26, 98.57, 98.61, 97.99, 97.98, 98.26, 96.33, 97.21, 98.48, 98.42, 96.73, 97.09, 97.75, 96.81, 95.69, 95.54, 97.68, 98.21, 98.54, 98.41, 98.35, 98.37, 98.71, 98.58, 98.73, 98.75, 98.75, 98.88, 98.78, 98.81, 98.86, 98.89, 98.74, 98.69, 98.86, 98.85, 98.74, 98.79, 98.85, 98.82, 98.84, 98.84, 98.85, 98.77, 98.82, 98.81, 98.65, 98.7, 98.67, 98.77, 98.64, 98.08, 98.12, 98.58, 98.06, 98.7, 98.47, 98.48, 98.53, 98.65, 98.66, 98.49, 98.54, 98.6, 98.36, 98.13, 98.19, 96.58, 97.34, 97.58, 98.18, 98.21, 97.79, 98.35, 98.56, 98.34, 98.1, 98.43, 98.47, 98.3, 98.01, 98.59, 98.1, 98.04, 97.58, 98.22, 98.39, 97.84, 96.63, 96.24, 98.28, 98.56, 98.79, 98.6, 98.66, 98.78, 98.81, 98.76, 98.86, 98.88, 98.84, 98.77, 98.85, 98.84, 98.81, 98.69, 98.66, 98.66, 98.5, 98.4, 98.16, 98.55, 98.45, 98.73, 98.72, 98.87, 98.79, 98.83, 98.86, 98.87, 98.89, 98.86, 98.86, 98.9, 98.82, 98.81, 98.79, 98.64, 98.64, 98.5, 98.52, 98.68, 98.56, 98.43, 98.64, 98.79, 98.74, 98.73, 98.79, 98.85, 98.85, 98.59, 98.56, 98.52, 96.55, 93.46]
|
[0.99, 0.85, 0.9, 0.61, 0.75, 0.15, 0.68, 0.58, 0.43, 0.27, 0.11, 0.0, 0.01, 0.01, 0.43, 0.46, 0.54, 0.92, 0.67, 0.46, 0.19, 0.2, 0.0, 0.0, 0.27, 0.02, 0.29, 0.74, 0.46, 0.49, 0.98, 0.83, 0.42, 0.89, 0.58, 0.52, 0.95, 0.99, 0.52, 0.8, 0.08, 0.25, 0.05, 0.0, 0.32, 0.05, 0.14, 0.62, 0.43, 0.57, 0.36, 0.47, 0.17, 0.22, 0.02, 0.36, 0.37, 0.66, 0.31, 0.11, 0.35, 0.25, 0.01, 0.68, 0.87, 0.24, 0.28, 0.68, 0.5, 0.04, 0.32, 0.67, 0.56, 0.24, 0.92, 0.42, 0.6, 0.46, 0.02, 0.47, 0.49, 0.0, 0.03, 0.46, 0.31, 0.0, 0.37, 0.35, 0.37, 0.23, 0.7, 0.65, 0.39, 0.7, 0.45, 0.71, 0.68, 0.76, 0.68, 0.78, 0.78, 0.89, 0.97, 1.0, 0.98, 0.98, 0.99, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.92, 1.0, 0.9, 0.94, 0.97, 0.93, 0.98, 1.0, 1.0, 1.0, 0.99, 0.99, 0.97, 0.99, 0.96, 1.0, 0.99, 1.0, 0.99, 0.98, 0.98, 0.95, 0.99, 0.99, 0.99, 0.98, 1.0, 1.0, 0.95, 0.87, 0.85, 0.92, 0.94, 0.97, 0.91, 1.0, 0.94, 0.97, 0.95, 0.98, 0.93, 0.99, 0.99, 0.99, 0.98, 0.93, 0.99, 0.94, 1.0, 1.0, 0.88, 1.0, 0.93, 0.99, 1.0, 0.99, 0.99, 0.95, 0.97, 0.96, 0.94, 0.89, 0.88, 0.92, 0.82, 0.91, 0.79, 0.95, 0.98, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 1.0, 0.94, 1.0, 1.0, 1.0, 0.85, 0.87, 0.91, 0.88, 0.87, 0.96, 0.94, 0.99, 0.81, 0.93, 0.73, 0.7, 0.79, 0.73, 0.73, 0.75, 0.59, 0.82, 0.85, 0.65, 0.78, 0.84, 0.61, 0.73, 0.92, 0.97, 0.64, 0.75, 0.84, 0.56, 0.71, 0.72, 0.56, 0.61, 0.29, 0.5, 0.79, 0.13, 0.77, 0.79, 0.98, 0.52, 0.9, 0.2, 0.84, 0.39, 0.21, 0.93, 0.36, 0.49, 0.0, 0.0, 0.0, 0.0, 0.05, 0.01, 0.31, 0.11, 0.11, 0.0, 0.24, 0.03, 0.0, 0.0, 0.15, 0.08, 0.0, 0.14, 0.66, 0.34, 0.58, 0.04, 0.47, 0.02, 0.12, 0.0, 0.17, 0.16, 0.52, 0.51, 0.35, 0.52, 0.45, 0.02, 0.49, 0.69, 0.05, 0.41, 0.77, 0.47, 0.71, 0.09, 0.65, 0.57, 0.07, 0.77, 0.35, 0.06, 0.15, 0.28, 0.0, 0.01, 0.39, 0.53, 0.01, 0.34, 0.01, 0.0, 0.0, 0.0, 0.13, 0.26, 0.32, 0.4, 0.12, 0.73, 0.13, 0.01, 0.24, 0.46, 0.04, 0.01, 0.5, 0.18, 0.73, 0.3, 0.01, 0.0, 0.17, 0.61, 0.09, 0.09, 0.48, 0.81, 0.56, 0.07, 0.06, 0.0, 0.0, 0.03, 0.02, 0.04, 0.14, 0.03, 0.26, 0.18, 0.74, 0.01, 0.01, 0.49, 0.38, 0.01, 0.1, 0.72, 0.27, 0.0, 0.57, 0.74, 0.54, 0.37, 0.08, 0.26, 0.04, 0.0, 0.01, 0.0, 0.03, 0.11, 0.21, 0.25, 0.22, 0.28, 0.57, 0.35, 0.0, 0.38, 0.5, 0.05, 0.33, 0.0, 0.21, 0.0, 0.08, 0.0, 0.0, 0.25, 0.26, 0.39, 0.35, 0.0, 0.06, 0.55, 0.23, 0.0, 0.23, 0.13, 0.0, 0.01, 0.31, 0.08, 0.0, 0.0, 0.49, 0.21, 0.07, 0.27, 0.17, 0.13, 0.2, 0.75, 0.27, 0.01, 0.29, 0.0, 0.03, 0.37, 0.45, 0.0, 0.03, 0.45, 0.36, 0.06, 0.22, 0.64, 0.23, 0.0, 0.16, 0.3, 0.0, 0.06, 0.54, 0.08, 0.0, 0.5, 0.32, 0.02, 0.1, 0.61, 0.09, 0.58, 0.62, 0.55, 0.78, 0.62, 0.49, 0.12, 0.48, 0.45, 0.27, 0.03, 0.44, 0.65, 0.29, 0.33, 0.87, 0.41, 0.99, 0.59, 0.48, 0.36, 0.83, 0.23, 0.03, 0.28, 0.53, 0.05, 0.02, 0.34, 0.11, 0.07, 0.35, 0.67, 0.45, 0.4, 0.09, 0.73, 0.22, 0.16, 0.12, 0.23, 0.0, 0.33, 0.24, 0.0, 0.07, 0.13, 0.0, 0.0, 0.53, 0.08, 0.06, 0.23, 0.5, 0.27, 0.09, 0.7, 0.74, 0.7, 0.81, 0.63, 0.82, 0.19, 0.65, 0.71, 0.03, 0.35, 0.53, 0.05, 0.07, 0.55, 0.18, 0.0, 0.42, 0.62, 0.0, 0.33, 0.74, 0.49, 0.8, 0.11, 0.21, 0.52, 0.28, 0.0, 0.0, 0.0, 0.0, 0.0, 0.14, 0.34, 0.16, 0.2, 0.61, 0.84]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 77.798897
| 0.488644
| 1,403
|
O43791
|
Q7Z7J5
|
33862460
|
UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
DPPA2
|
MSDANLDSSKKNFLEGEVDDEESVILTLVPVKDDANMEQMEPSVSSTSDVKLEKPKKYNPGHLLQTNEQFTAPQKARCKIPALPLPTILPPINKVCRDTLRDWCQQLGLSTNGKKIEVYLRLHRHAYPEQRQDMPEMSQETRLQRCSRKRKAVTKRARLQRSYEMNERAEETNTVEVITSAPGAMLASWARIAARAVQPKALNSCSIPVSVEAFLMQASGVRWCVVHGRLLSADTKGWVRLQFHAGQAWVPTTHRRMISLFLLPACIFPSPGIEDNMLCPDCAKRNKKMMKRLMTVEK
|
Homo sapiens
|
Nucleus
|
Tissue enriched (testis)
|
{'Ciliated cells': '0.0', 'Basal respiratory cells': '0.0', 'Club cells': '0.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.0', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.023', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.017', 'Breast myoepithelial cells': '-0.110', 'Glandular and luminal cells': '0.1', 'Secretory cells': '0.0', 'Basal keratinocytes': '0.0', 'Suprabasal keratinocytes': '0.0', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '-0.032', 'Alveolar cells type 2': '0.029', 'Salivary duct cells': '0.0', 'Ductal cells': '0.080', 'Hepatocytes': '0.081', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.237', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.048', 'Sertoli cells': '0.471', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.360', 'Excitatory neurons': '0.3', 'Inhibitory neurons': '0.2', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.1', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '0.061', 'Spermatogonia': '0.677', 'Spermatocytes': '0.179', 'Early spermatids': '-0.262', 'Late spermatids': '-0.360', 'Oocytes': '0.0', 'Cytotrophoblasts': '3.7', 'Syncytiotrophoblasts': '1.8', 'Extravillous trophoblasts': '14.0', 'Endothelial cells': '0.0', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '-0.056', 'Skeletal myocytes': '-0.034', 'Smooth muscle cells': '0.0', 'Adipocytes': '0.0', 'Melanocytes': '-0.020', 'Fibroblasts': '0.0', 'Peritubular cells': '0.249', 'Endometrial stromal cells': '0.0', 'Ovarian stromal cells': '0.0', 'Undifferentiated cells': '0.0', 'T-cells': '0.0', 'B-cells': '0.0', 'Plasma cells': '0.0', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.0', 'Hofbauer cells': '0.2', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '-0.039', 'Erythroid cells': '-0.031', 'Adipocytes (Subcutaneous)': '-0.057', 'Adipocytes (Visceral)': '0.014', 'Breast glandular cells (progenitors)': '0.101', 'Adipocytes (Breast)': '-0.052', 'Colon enterocytes': '-0.092', 'Colon enteroendocrine cells': '-0.063', 'Enteric glia cells': '0.015', 'Mitotic cells (Colon)': '-0.009', 'Mitotic cells (Heart)': '-0.084', 'Podocytes': '-0.267', 'Ascending Loop of Henle cells': '0.560', 'Intercalated cells': '-0.182', 'Cholangiocyte': '-0.124', 'NK-cells (Liver)': '0.016', 'Respiratory ciliated cells': '0.023', 'Mitotic cells (Lung)': '0.017', 'NK-cells (Lung)': '-0.057', 'B-cells (Lung)': '-0.020', 'Alpha cells': '-0.017', 'Beta cells': '0.055', 'Prostate glandular cells': '-0.030', 'Prostate basal glandular cells': '-0.163', 'Urothelial cells': '-0.098', 'Keratinocyte (other)': '-0.025', 'Keratinocyte (granular)': '0.113', 'Hair cortex cells': '0.009', 'Inner root sheath cells': '-0.028', 'Outer root sheath cells': '-0.092', 'Sebaceous gland cells': '-0.114', 'Eccrine sweat gland cells': '0.025', 'Adipocytes (Skin)': '0.032', 'Mitotic cells (Skin)': '0.070', 'Parietal cells': '0.023', 'Chief cells': '-0.034', 'Gastric mucous cells': '0.006', 'Gastric enteroendocrine cells': '-0.016', 'Mitotic cells (Stomach)': '0.002', 'Parafollicular cells': '0.010', 'Thyroid glandular cells': '-0.002', 'Mitotic cells (Thyroid)': '0.070', 'Adrenal cortex cells': '0.021', 'Adrenal medulla cells': '0.140', 'Mitotic cells (Adrenal gland)': '0.005', 'Minor salivary glandular cells': '0.101', 'Minor salivary gland ductal cells': '0.053', 'Minor salivary gland basal cells': '-0.099', 'Mitotic cells (Minor salivary gland)': '-0.013', 'Adipocytes (Minor salivary gland)': '-0.096', 'Somatotropes': '0.110', 'Lactotropes': '0.111', 'Gonadotropes': '0.063', 'Corticotropes': '0.076', 'Thyrotropes': '0.053', 'Undifferentiated cells (Pituitary gland)': '0.039', 'Mitotic cells (Spleen)': '-0.047', 'Platelets': '0.001', 'Erythrocytes': '-0.035', 'Hematopoietic stem cells': '0.027', 'B-cells (Spleen)': '0.052', 'NK-cells (Spleen)': '0.038', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.0', 'Cge interneuron': '0.1', 'Deep-layer corticothalamic and 6b': '0.1', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.1', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '0.3', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.1', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.1', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.1', 'Miscellaneous': '0.1', 'Splatter': '0.1', 'Thalamic excitatory': '0.1', 'Upper rhombic lip': '0.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '0.1', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.3', 'Choroid plexus epithelial cell': '0.1', 'Committed oligodendrocyte precursor': '0.4', 'Ependymal cell': '0.2', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '0.0', 'Endothelial cell': '0.0', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.1', 'Leukocyte': '0.1', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.2', 'Plasmacytoid DC': '0.5', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Terminal effector memory CD4 T-cell': '0.1', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Non-switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.3', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
| null |
{'Adipose Tissue': 0.002136453488372, 'Adrenal Gland': 0.003163992248062, 'Bladder': 0.0055271428571428, 'Blood': 0.0218937502691065, 'Blood Vessel': 0.0023163670411985, 'Brain': 0.0035257872823618, 'Breast': 0.0030132461873638, 'Cervix Uteri': 0.0208578947368421, 'Colon': 0.0016382798459563, 'Esophagus': 0.0016844705882352, 'Fallopian Tube': 0.0, 'Heart': 0.0019862833914053, 'Kidney': 0.103637415730337, 'Liver': 0.0064391592920353, 'Lung': 0.0056841003460207, 'Muscle': 0.0014966127023661, 'Nerve': 0.0024745880452342, 'Ovary': 0.0025503888888888, 'Pancreas': 0.0013082926829268, 'Pituitary': 0.059536183745583, 'Prostate': 0.0045041632653061, 'Salivary Gland': 0.0006437037037037, 'Skin': 0.001616362631288, 'Small Intestine': 0.0121006417112299, 'Spleen': 0.015491244813278, 'Stomach': 0.0018837604456824, 'Testis': 6.790174515235457, 'Thyroid': 0.0041877641653905, 'Uterus': 0.0034244366197183, 'Vagina': 0.0101178205128205}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[48.63, 41.38, 41.39, 46.88, 47.21, 51.19, 46.96, 44.38, 43.71, 43.49, 43.04, 38.14, 33.56, 42.19, 35.6, 36.07, 32.67, 45.62, 41.73, 43.05, 53.56, 50.25, 51.92, 61.09, 60.89, 51.99, 67.53, 61.19, 68.37, 69.96, 66.2, 67.11, 60.96, 55.58, 50.87, 47.11, 51.69, 45.09, 39.35, 42.04, 45.59, 44.25, 40.48, 46.19, 38.29, 45.84, 42.37, 54.24, 43.61, 49.25, 43.96, 42.0, 48.04, 46.47, 44.18, 46.12, 40.31, 38.67, 40.63, 41.12, 35.0, 32.49, 35.09, 39.85, 35.41, 36.84, 37.21, 41.6, 37.41, 37.44, 40.93, 38.53, 39.49, 40.76, 44.33, 38.8, 41.7, 38.34, 45.21, 51.74, 56.29, 57.51, 65.58, 78.48, 80.2, 81.42, 78.88, 82.03, 87.09, 86.56, 86.39, 87.21, 86.28, 87.3, 88.15, 89.88, 90.62, 91.11, 90.03, 91.84, 91.94, 90.2, 93.26, 91.82, 92.13, 89.58, 87.56, 89.28, 91.59, 90.38, 90.9, 90.03, 90.84, 92.11, 92.56, 92.02, 91.69, 93.44, 92.24, 90.88, 93.14, 91.73, 88.55, 88.57, 89.12, 86.3, 86.12, 80.83, 76.28, 75.77, 67.53, 61.03, 56.49, 51.38, 46.28, 41.72, 37.07, 34.91, 35.52, 37.01, 34.78, 32.18, 38.41, 34.42, 32.23, 34.12, 37.25, 40.88, 39.95, 40.81, 43.8, 38.02, 43.89, 44.71, 43.66, 35.97, 41.19, 40.73, 44.82, 40.85, 34.65, 47.45, 35.91, 44.39, 35.57, 43.97, 36.31, 44.38, 39.7, 38.97, 42.07, 42.26, 44.23, 42.02, 48.6, 58.05, 63.75, 67.23, 71.48, 83.87, 80.42, 84.09, 85.79, 84.19, 83.73, 87.2, 87.43, 85.96, 88.34, 90.32, 90.18, 89.32, 89.0, 88.57, 85.96, 86.46, 85.67, 86.64, 85.06, 85.19, 84.98, 87.63, 90.92, 91.07, 90.24, 88.77, 84.89, 80.92, 69.56, 65.45, 69.96, 79.43, 84.77, 87.47, 88.36, 87.02, 89.49, 87.52, 88.21, 92.62, 93.86, 95.22, 96.56, 96.97, 95.25, 95.48, 95.91, 95.19, 96.0, 96.33, 95.84, 95.1, 94.46, 92.34, 91.47, 92.22, 93.14, 95.89, 95.16, 94.9, 94.44, 92.71, 90.11, 84.44, 83.95, 85.36, 87.79, 92.84, 94.34, 95.47, 94.5, 92.51, 89.91, 87.31, 88.36, 91.94, 94.28, 94.62, 94.84, 95.11, 94.37, 94.57, 93.23, 92.25, 89.89, 85.77, 87.63, 88.5, 92.86, 92.0, 91.38, 89.96, 92.1, 91.79, 92.1, 93.86, 94.92, 96.4, 96.11, 96.25, 96.93, 97.3, 96.31, 96.48, 96.98, 96.2, 94.95, 94.93, 92.72, 91.86, 91.33, 90.01, 86.97, 80.91, 79.1, 67.93, 56.89, 46.61]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.84, 1.0, 0.92, 0.94, 0.91, 0.89, 0.83, 0.74, 0.68, 0.81, 0.77, 0.75, 0.78, 0.8, 0.89, 0.79, 0.87, 0.8, 0.82, 0.74, 0.88, 0.89, 0.94, 0.93, 0.92, 0.83, 0.86, 0.83, 0.93, 0.97, 0.99, 0.97, 0.95, 1.0, 0.93, 0.96, 0.93, 0.93, 0.96, 0.93, 0.94, 0.95, 0.93, 0.91, 0.94, 0.86, 0.96, 0.98, 0.93, 0.91, 0.86, 0.88, 0.74, 0.9, 0.85, 0.86, 0.81, 0.88, 0.91, 0.9, 0.75, 0.88, 0.76, 0.88, 0.84, 0.82, 0.71, 0.52, 0.79, 0.39, 0.27, 0.92, 0.74, 0.02, 0.39, 0.31, 0.16, 0.87, 0.85, 0.09, 0.51, 0.45, 0.51, 0.16, 0.0, 0.36, 0.45, 0.07, 0.0, 0.65, 0.4, 0.39, 0.82, 0.15, 0.46, 0.26, 0.68, 0.4, 0.69, 0.31, 0.33, 0.42, 0.0, 0.08, 0.38, 0.29, 0.0, 0.05, 0.85, 0.63, 0.51, 0.09, 0.75, 0.96, 0.3, 0.92, 0.48, 0.72, 0.42, 0.73, 0.88, 0.75, 0.74, 0.88, 0.9, 0.9, 0.96, 0.92, 0.84, 0.96, 0.78, 0.89, 0.99, 1.0, 0.99, 1.0, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 0.88, 0.96, 0.82, 0.82, 0.8, 0.8, 0.94, 0.89, 0.88, 0.86, 0.66, 0.79, 0.71, 0.7, 0.76, 0.7, 0.82, 0.64, 0.63, 0.5, 0.54, 0.35, 0.25, 0.41, 0.63, 0.37, 0.13, 0.56, 0.55, 0.6, 0.14, 0.35, 0.48, 0.32, 0.23, 0.76, 0.38, 0.58, 0.57, 0.78, 0.52, 0.01, 0.28, 0.32, 0.77, 0.17, 0.41, 0.94, 0.94, 0.28, 0.55, 0.05, 0.35, 0.14, 0.82, 0.64, 0.41, 0.91, 0.47, 0.67, 0.18, 0.09, 0.0, 0.12, 0.19, 0.34, 0.14, 0.59, 0.48, 0.25, 0.41, 0.02, 0.45, 0.46, 0.8, 0.44, 0.01, 0.03, 0.22, 0.04, 0.13, 0.65, 0.39, 0.81, 0.92, 0.23, 0.22, 0.08, 0.01, 0.04, 0.17, 0.57, 0.76, 0.84, 0.56, 0.0, 0.07, 0.04, 0.13, 0.09, 0.15, 0.26, 0.34, 0.27, 0.28, 0.57, 0.86, 0.23, 0.73, 0.97, 0.98, 0.37, 0.44, 0.53, 0.28, 0.01, 0.0, 0.05, 0.22, 0.56, 0.0, 0.13, 0.7, 0.46, 0.0, 0.43, 0.59, 0.35, 0.08, 0.67, 0.6, 0.22, 0.16, 0.65, 0.81, 0.52, 0.85]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 69.533121
| 0.611946
| 2,392
|
O43791
|
Q99836
|
31406379
|
UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
MYD88
|
MAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGHMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWTRLAKALSLP
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '9.8', 'Basal respiratory cells': '12.2', 'Club cells': '18.9', 'Ionocytes': '18.0', 'Mucus glandular cells': '17.1', 'Serous glandular cells': '4.9', 'Gastric mucus-secreting cells': '20.6', 'Proximal enterocytes': '29.2', 'Paneth cells': '29.0', 'Distal enterocytes': '35.6', 'Intestinal goblet cells': '16.7', 'Exocrine glandular cells': '-0.774', 'Basal prostatic cells': '8.2', 'Prostatic glandular cells': '7.1', 'Breast glandular cells': '0.226', 'Breast myoepithelial cells': '0.066', 'Glandular and luminal cells': '17.9', 'Secretory cells': '11.8', 'Basal keratinocytes': '15.9', 'Suprabasal keratinocytes': '19.9', 'Basal squamous epithelial cells': '12.9', 'Squamous epithelial cells': '15.9', 'Alveolar cells type 1': '-0.072', 'Alveolar cells type 2': '0.251', 'Salivary duct cells': '15.4', 'Ductal cells': '0.721', 'Hepatocytes': '0.585', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.387', 'Distal tubular cells': '9.2', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.054', 'Sertoli cells': '0.186', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '11.4', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '0.395', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '1.2', 'Horizontal cells': '0.6', 'Astrocytes': '1.9', 'Oligodendrocyte precursor cells': '2.4', 'Oligodendrocytes': '0.3', 'Microglial cells': '1.8', 'Muller glia cells': '5.6', 'Schwann cells': '0.181', 'Spermatogonia': '0.268', 'Spermatocytes': '0.109', 'Early spermatids': '-0.017', 'Late spermatids': '-0.284', 'Oocytes': '0.0', 'Cytotrophoblasts': '14.9', 'Syncytiotrophoblasts': '11.6', 'Extravillous trophoblasts': '25.9', 'Endothelial cells': '18.2', 'Lymphatic endothelial cells': '9.6', 'Cardiomyocytes': '0.178', 'Skeletal myocytes': '-0.182', 'Smooth muscle cells': '8.4', 'Adipocytes': '13.3', 'Melanocytes': '0.267', 'Fibroblasts': '10.7', 'Peritubular cells': '0.170', 'Endometrial stromal cells': '31.4', 'Ovarian stromal cells': '5.3', 'Undifferentiated cells': '13.7', 'T-cells': '19.9', 'B-cells': '19.9', 'Plasma cells': '12.4', 'Nk-cells': '22.5', 'Granulocytes': '16.7', 'Monocytes': '149.0', 'Macrophages': '64.0', 'Hofbauer cells': '46.4', 'Kupffer cells': '78.9', 'Dendritic cells': '48.7', 'Langerhans cells': '0.390', 'Erythroid cells': '-0.200', 'Adipocytes (Subcutaneous)': '-0.158', 'Adipocytes (Visceral)': '0.065', 'Breast glandular cells (progenitors)': '0.038', 'Adipocytes (Breast)': '-0.081', 'Colon enterocytes': '0.219', 'Colon enteroendocrine cells': '0.006', 'Enteric glia cells': '-0.477', 'Mitotic cells (Colon)': '0.396', 'Mitotic cells (Heart)': '0.513', 'Podocytes': '-0.162', 'Ascending Loop of Henle cells': '0.217', 'Intercalated cells': '-0.125', 'Cholangiocyte': '0.188', 'NK-cells (Liver)': '-0.194', 'Respiratory ciliated cells': '-0.161', 'Mitotic cells (Lung)': '0.258', 'NK-cells (Lung)': '-0.040', 'B-cells (Lung)': '-0.141', 'Alpha cells': '0.381', 'Beta cells': '0.202', 'Prostate glandular cells': '-0.130', 'Prostate basal glandular cells': '0.367', 'Urothelial cells': '0.426', 'Keratinocyte (other)': '0.209', 'Keratinocyte (granular)': '0.097', 'Hair cortex cells': '-0.059', 'Inner root sheath cells': '-0.020', 'Outer root sheath cells': '0.018', 'Sebaceous gland cells': '0.056', 'Eccrine sweat gland cells': '-0.244', 'Adipocytes (Skin)': '-0.088', 'Mitotic cells (Skin)': '0.161', 'Parietal cells': '-0.379', 'Chief cells': '-0.369', 'Gastric mucous cells': '0.203', 'Gastric enteroendocrine cells': '-0.203', 'Mitotic cells (Stomach)': '0.475', 'Parafollicular cells': '-0.066', 'Thyroid glandular cells': '0.046', 'Mitotic cells (Thyroid)': '0.269', 'Adrenal cortex cells': '0.509', 'Adrenal medulla cells': '0.100', 'Mitotic cells (Adrenal gland)': '0.419', 'Minor salivary glandular cells': '0.467', 'Minor salivary gland ductal cells': '-0.242', 'Minor salivary gland basal cells': '0.636', 'Mitotic cells (Minor salivary gland)': '0.688', 'Adipocytes (Minor salivary gland)': '0.219', 'Somatotropes': '-0.246', 'Lactotropes': '-0.277', 'Gonadotropes': '-0.083', 'Corticotropes': '0.099', 'Thyrotropes': '0.213', 'Undifferentiated cells (Pituitary gland)': '0.247', 'Mitotic cells (Spleen)': '-0.051', 'Platelets': '0.313', 'Erythrocytes': '-0.046', 'Hematopoietic stem cells': '0.191', 'B-cells (Spleen)': '-0.040', 'NK-cells (Spleen)': '0.049', 'Amygdala excitatory': '0.2', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '1.0', 'Deep-layer corticothalamic and 6b': '0.2', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.4', 'Eccentric medium spiny neuron': '3.8', 'Hippocampal ca1-3': '1.7', 'Hippocampal ca4': '0.5', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '1.2', 'Mammillary body': '0.1', 'Medium spiny neuron': '1.9', 'Mge interneuron': '0.7', 'Midbrain-derived inhibitory': '0.9', 'Miscellaneous': '0.6', 'Splatter': '0.9', 'Thalamic excitatory': '0.2', 'Upper rhombic lip': '2.3', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '2.9', 'Bergmann glia': '1.7', 'Central nervous system macrophage': '10.8', 'Choroid plexus epithelial cell': '0.8', 'Committed oligodendrocyte precursor': '1.6', 'Ependymal cell': '3.2', 'Oligodendrocyte': '0.5', 'Oligodendrocyte precursor cell': '4.3', 'Endothelial cell': '9.4', 'Pericyte': '2.6', 'Vascular associated smooth muscle cell': '2.7', 'Fibroblast': '5.1', 'Leukocyte': '19.9', 'Basophil': '404.1', 'Eosinophil': '297.8', 'Neutrophil': '886.8', 'Classical monocyte': '375.8', 'Non-classical monocyte': '679.3', 'Intermediate monocyte': '840.4', 'T-reg': '75.8', 'GdT-cell': '68.4', 'MAIT T-cell': '69.7', 'Memory CD4 T-cell': '61.1', 'Naive CD4 T-cell': '62.8', 'Memory CD8 T-cell': '70.0', 'Naive CD8 T-cell': '72.3', 'Memory B-cell': '43.9', 'Naive B-cell': '62.3', 'Plasmacytoid DC': '365.5', 'Myeloid DC': '472.4', 'NK-cell': '131.4', 'Total PBMC': '237.7', 'Vd2 gdTCR': '89.0', 'Memory CD4 T-cell Th1\\/Th17': '89.3', 'Memory CD4 T-cell Th17': '101.1', 'Memory CD4 T-cell Th2': '93.4', 'Non-Vd2 gdTCR': '104.1', 'Memory CD4 T-cell Th1': '93.7', 'Memory CD4 T-cell TFH': '86.6', 'Terminal effector memory CD4 T-cell': '115.9', 'Central memory CD8 T-cell': '58.3', 'Effector memory CD8 T-cell': '119.8', 'Terminal effector memory CD8 T-cell': '126.9', 'Non-switched memory B-cell': '116.2', 'Plasmablast': '71.5', 'Switched memory B-cell': '89.7', 'Exhausted memory B-cell': '105.2', 'Progenitor cell': '70.4', 'Memory T-reg': '134.3', 'Naive CD4 T-cell activated': '56.4', 'Naive CD8 T-cell activated': '95.6', 'Naive T-reg': '61.0'}
|
2JS7, 2Z5V, 3MOP, 4DOM, 4EO7, 6I3N, 7BEQ, 7BER, 7L6W
|
{'Adipose Tissue': 41.232636212624584, 'Adrenal Gland': 26.96146511627907, 'Bladder': 37.261428571428574, 'Blood': 213.4942045209903, 'Blood Vessel': 26.086257677902623, 'Brain': 7.5514469719909165, 'Breast': 35.42065359477124, 'Cervix Uteri': 34.53473684210526, 'Colon': 32.06323876765083, 'Esophagus': 41.32181107266436, 'Fallopian Tube': 38.894444444444446, 'Heart': 9.171952380952382, 'Kidney': 18.58914606741573, 'Liver': 34.295938053097345, 'Lung': 71.75977508650519, 'Muscle': 3.3121280199252805, 'Nerve': 30.898885298869143, 'Ovary': 29.52291111111111, 'Pancreas': 11.449051829268292, 'Pituitary': 26.864840989399298, 'Prostate': 32.53885714285715, 'Salivary Gland': 36.99355555555556, 'Skin': 38.123512437810945, 'Small Intestine': 50.07213903743315, 'Spleen': 106.37622406639004, 'Stomach': 28.16547075208914, 'Testis': 16.263168975069252, 'Thyroid': 29.427385911179172, 'Uterus': 31.81661971830986, 'Vagina': 46.61365384615385}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[39.09, 39.07, 34.75, 36.99, 30.37, 40.73, 32.43, 33.31, 29.5, 33.61, 33.8, 35.78, 37.3, 42.8, 50.2, 57.52, 63.53, 65.38, 77.08, 81.86, 85.52, 81.75, 81.96, 83.98, 85.22, 87.47, 85.81, 89.0, 89.36, 88.99, 88.13, 90.02, 89.15, 90.21, 88.11, 86.57, 87.64, 87.34, 84.06, 78.64, 75.81, 73.15, 76.4, 79.33, 82.96, 87.47, 89.43, 89.5, 90.29, 89.79, 90.48, 90.38, 88.9, 87.19, 88.1, 88.46, 90.09, 88.55, 91.02, 89.5, 89.91, 89.13, 89.93, 88.93, 89.56, 89.76, 88.71, 87.72, 89.65, 90.37, 90.33, 89.47, 89.84, 91.24, 90.18, 87.95, 88.41, 88.12, 85.55, 80.77, 83.2, 78.86, 79.16, 84.04, 88.55, 88.12, 86.8, 87.41, 89.06, 88.85, 88.95, 89.17, 88.81, 88.92, 89.55, 87.48, 85.65, 83.76, 83.2, 86.2, 86.46, 87.0, 87.12, 87.71, 87.53, 85.32, 88.43, 89.06, 88.6, 88.06, 89.69, 90.83, 89.37, 89.55, 90.03, 88.9, 88.02, 89.49, 88.61, 84.46, 85.24, 84.41, 80.78, 78.37, 77.95, 74.95, 61.53, 59.83, 59.96, 56.65, 57.15, 60.52, 58.34, 51.4, 50.44, 54.25, 54.27, 52.14, 48.6, 51.59, 50.93, 57.72, 58.75, 60.97, 61.73, 63.69, 71.87, 70.86, 69.98, 71.6, 69.02, 64.42, 62.03, 62.06, 63.44, 61.94, 66.27, 72.99, 79.46, 83.6, 87.51, 89.05, 91.02, 90.91, 92.42, 91.99, 91.93, 90.15, 88.24, 90.32, 90.92, 89.81, 91.76, 92.48, 92.49, 90.87, 91.69, 91.75, 90.23, 89.34, 90.12, 88.78, 82.5, 82.07, 80.78, 80.25, 79.75, 80.34, 86.14, 85.7, 88.37, 87.4, 86.67, 80.69, 77.58, 75.13, 75.72, 75.1, 72.74, 75.44, 72.92, 72.37, 77.39, 80.36, 82.75, 82.54, 83.09, 84.77, 86.13, 84.8, 85.18, 86.28, 84.88, 84.4, 83.74, 86.69, 86.04, 88.86, 90.33, 92.34, 92.3, 93.15, 91.44, 91.31, 91.84, 91.24, 90.43, 88.13, 89.16, 88.28, 87.22, 83.79, 84.9, 87.91, 88.48, 87.39, 85.19, 87.44, 87.44, 85.31, 83.85, 84.45, 81.69, 69.4, 65.61, 61.82, 52.68, 50.82, 58.77, 66.03, 81.22, 87.44, 90.08, 91.37, 92.74, 92.13, 91.94, 90.37, 88.2, 86.93, 86.6, 86.69, 85.2, 81.76, 81.42, 81.66, 78.89, 80.84, 80.36, 80.4, 84.7, 85.82, 88.03, 90.01, 90.38, 91.1, 88.82, 88.36, 87.8, 86.18, 84.53, 84.71, 85.58, 86.81, 91.4, 90.74, 89.71, 90.25, 91.78, 91.66, 90.39, 89.48, 89.93, 87.93, 85.32, 77.22]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.97, 0.92, 0.92, 0.95, 0.97, 0.96, 0.67, 0.85, 0.83, 0.68, 0.2, 0.54, 0.88, 0.09, 0.4, 0.02, 0.52, 0.07, 0.05, 0.51, 0.62, 0.81, 0.04, 0.17, 0.66, 0.42, 0.01, 0.04, 0.71, 0.25, 0.01, 0.28, 0.53, 0.64, 0.4, 1.0, 0.99, 0.36, 0.23, 0.15, 0.02, 0.4, 0.24, 0.01, 0.0, 0.62, 0.35, 0.05, 0.73, 0.11, 0.66, 0.65, 0.76, 0.35, 0.12, 0.51, 0.63, 0.11, 0.39, 0.74, 0.32, 0.93, 0.38, 0.09, 0.01, 0.21, 0.53, 0.0, 0.04, 0.5, 0.41, 0.04, 0.41, 0.84, 0.32, 0.96, 0.58, 0.21, 0.15, 0.01, 0.11, 0.44, 0.03, 0.23, 0.54, 0.03, 0.0, 0.54, 0.67, 0.21, 0.56, 0.05, 0.54, 0.44, 0.01, 0.25, 0.76, 0.4, 0.0, 0.34, 0.55, 0.35, 0.06, 0.4, 0.51, 0.1, 0.03, 0.54, 0.56, 0.28, 0.34, 0.55, 0.57, 0.42, 0.57, 0.61, 0.49, 0.61, 0.75, 0.81, 0.62, 0.66, 0.95, 0.78, 0.82, 0.95, 0.73, 0.83, 0.64, 0.9, 0.84, 0.59, 0.57, 0.89, 0.55, 0.71, 0.71, 0.21, 0.53, 0.32, 0.03, 0.03, 0.54, 0.77, 0.12, 0.3, 0.92, 0.73, 0.45, 0.72, 0.83, 0.55, 0.15, 0.75, 0.07, 0.2, 0.0, 0.01, 0.02, 0.01, 0.14, 0.12, 0.66, 0.6, 0.0, 0.35, 0.78, 0.09, 0.02, 0.58, 0.28, 0.0, 0.14, 0.58, 0.31, 0.0, 0.52, 0.66, 0.19, 0.92, 0.4, 0.88, 0.09, 0.54, 0.06, 0.0, 0.07, 0.34, 0.69, 0.55, 0.14, 0.22, 0.48, 0.95, 1.0, 0.49, 0.5, 0.64, 0.38, 0.46, 0.05, 0.05, 0.16, 0.09, 0.01, 0.05, 0.57, 0.68, 0.04, 0.06, 0.58, 0.08, 0.03, 0.02, 0.0, 0.0, 0.0, 0.0, 0.19, 0.35, 0.04, 0.34, 0.64, 0.14, 0.77, 0.53, 0.03, 0.46, 0.34, 0.12, 0.07, 0.52, 0.19, 0.06, 0.22, 0.61, 0.29, 0.21, 0.86, 0.53, 0.91, 0.93, 0.68, 0.76, 0.19, 0.12, 0.09, 0.0, 0.0, 0.25, 0.23, 0.37, 0.85, 0.21, 0.93, 0.44, 0.91, 0.32, 0.21, 0.54, 0.48, 0.0, 0.73, 0.95, 0.28, 0.79, 0.39, 0.25, 0.3, 0.19, 0.42, 0.41, 0.74, 0.77, 0.37, 0.43, 0.85, 0.75, 0.07, 0.13, 0.51, 0.71, 0.01, 0.0, 0.56, 0.32, 0.0, 0.38, 0.58, 0.77]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 80.312162
| 0.421689
| 2,387
|
O43791
|
Q9BYW2
|
27614073
|
UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
SETD2
|
MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE
|
Homo sapiens
|
Nucleus, Chromosome
|
Low tissue specificity
|
{'Ciliated cells': '49.3', 'Basal respiratory cells': '16.5', 'Club cells': '38.2', 'Ionocytes': '16.2', 'Mucus glandular cells': '79.1', 'Serous glandular cells': '50.4', 'Gastric mucus-secreting cells': '61.9', 'Proximal enterocytes': '24.4', 'Paneth cells': '31.6', 'Distal enterocytes': '31.2', 'Intestinal goblet cells': '31.0', 'Exocrine glandular cells': '-0.603', 'Basal prostatic cells': '52.6', 'Prostatic glandular cells': '79.3', 'Breast glandular cells': '0.512', 'Breast myoepithelial cells': '0.503', 'Glandular and luminal cells': '67.7', 'Secretory cells': '39.3', 'Basal keratinocytes': '48.8', 'Suprabasal keratinocytes': '45.9', 'Basal squamous epithelial cells': '69.1', 'Squamous epithelial cells': '63.3', 'Alveolar cells type 1': '0.430', 'Alveolar cells type 2': '-0.304', 'Salivary duct cells': '85.9', 'Ductal cells': '0.584', 'Hepatocytes': '0.445', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.166', 'Distal tubular cells': '3.1', 'Collecting duct cells': '9.7', 'Mesothelial cells': '0.414', 'Sertoli cells': '0.313', 'Granulosa cells': '33.1', 'Enteroendocrine cells': '23.2', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '0.254', 'Excitatory neurons': '126.9', 'Inhibitory neurons': '124.0', 'Cone photoreceptor cells': '28.9', 'Rod photoreceptor cells': '42.5', 'Bipolar cells': '35.7', 'Horizontal cells': '39.0', 'Astrocytes': '109.9', 'Oligodendrocyte precursor cells': '106.1', 'Oligodendrocytes': '133.2', 'Microglial cells': '142.2', 'Muller glia cells': '20.4', 'Schwann cells': '0.189', 'Spermatogonia': '0.508', 'Spermatocytes': '0.736', 'Early spermatids': '-0.019', 'Late spermatids': '-0.328', 'Oocytes': '25.0', 'Cytotrophoblasts': '21.0', 'Syncytiotrophoblasts': '17.8', 'Extravillous trophoblasts': '13.4', 'Endothelial cells': '49.7', 'Lymphatic endothelial cells': '55.9', 'Cardiomyocytes': '0.616', 'Skeletal myocytes': '-0.224', 'Smooth muscle cells': '44.4', 'Adipocytes': '53.0', 'Melanocytes': '0.259', 'Fibroblasts': '42.3', 'Peritubular cells': '0.276', 'Endometrial stromal cells': '68.4', 'Ovarian stromal cells': '36.4', 'Undifferentiated cells': '25.0', 'T-cells': '75.4', 'B-cells': '72.4', 'Plasma cells': '42.6', 'Nk-cells': '71.7', 'Granulocytes': '44.6', 'Monocytes': '75.7', 'Macrophages': '51.6', 'Hofbauer cells': '19.7', 'Kupffer cells': '26.2', 'Dendritic cells': '70.7', 'Langerhans cells': '0.323', 'Erythroid cells': '0.067', 'Adipocytes (Subcutaneous)': '-0.065', 'Adipocytes (Visceral)': '-0.297', 'Breast glandular cells (progenitors)': '0.456', 'Adipocytes (Breast)': '-0.405', 'Colon enterocytes': '-0.227', 'Colon enteroendocrine cells': '0.258', 'Enteric glia cells': '0.098', 'Mitotic cells (Colon)': '-0.192', 'Mitotic cells (Heart)': '0.521', 'Podocytes': '-0.102', 'Ascending Loop of Henle cells': '0.491', 'Intercalated cells': '-0.011', 'Cholangiocyte': '0.324', 'NK-cells (Liver)': '-0.234', 'Respiratory ciliated cells': '0.124', 'Mitotic cells (Lung)': '-0.211', 'NK-cells (Lung)': '0.393', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.396', 'Beta cells': '0.238', 'Prostate glandular cells': '-0.110', 'Prostate basal glandular cells': '0.232', 'Urothelial cells': '0.178', 'Keratinocyte (other)': '0.486', 'Keratinocyte (granular)': '0.088', 'Hair cortex cells': '-0.169', 'Inner root sheath cells': '-0.095', 'Outer root sheath cells': '-0.003', 'Sebaceous gland cells': '-0.029', 'Eccrine sweat gland cells': '-0.142', 'Adipocytes (Skin)': '-0.260', 'Mitotic cells (Skin)': '0.337', 'Parietal cells': '-0.596', 'Chief cells': '-0.512', 'Gastric mucous cells': '-0.368', 'Gastric enteroendocrine cells': '-0.401', 'Mitotic cells (Stomach)': '0.033', 'Parafollicular cells': '0.110', 'Thyroid glandular cells': '0.523', 'Mitotic cells (Thyroid)': '-0.065', 'Adrenal cortex cells': '0.543', 'Adrenal medulla cells': '0.016', 'Mitotic cells (Adrenal gland)': '0.297', 'Minor salivary glandular cells': '0.523', 'Minor salivary gland ductal cells': '0.220', 'Minor salivary gland basal cells': '0.355', 'Mitotic cells (Minor salivary gland)': '0.365', 'Adipocytes (Minor salivary gland)': '0.142', 'Somatotropes': '0.109', 'Lactotropes': '0.021', 'Gonadotropes': '0.013', 'Corticotropes': '-0.099', 'Thyrotropes': '0.159', 'Undifferentiated cells (Pituitary gland)': '0.247', 'Mitotic cells (Spleen)': '-0.206', 'Platelets': '-0.186', 'Erythrocytes': '-0.099', 'Hematopoietic stem cells': '-0.289', 'B-cells (Spleen)': '0.407', 'NK-cells (Spleen)': '0.368', 'Amygdala excitatory': '222.9', 'Cerebellar inhibitory': '173.5', 'Cge interneuron': '183.2', 'Deep-layer corticothalamic and 6b': '212.2', 'Deep-layer intratelencephalic': '212.9', 'Deep-layer near-projecting': '190.4', 'Eccentric medium spiny neuron': '220.8', 'Hippocampal ca1-3': '205.3', 'Hippocampal ca4': '200.5', 'Hippocampal dentate gyrus': '234.9', 'Lamp5-lhx6 and chandelier': '186.1', 'Lower rhombic lip': '181.5', 'Mammillary body': '227.7', 'Medium spiny neuron': '238.9', 'Mge interneuron': '194.0', 'Midbrain-derived inhibitory': '237.9', 'Miscellaneous': '196.3', 'Splatter': '187.9', 'Thalamic excitatory': '194.4', 'Upper rhombic lip': '246.7', 'Upper-layer intratelencephalic': '215.0', 'Astrocyte': '208.4', 'Bergmann glia': '201.5', 'Central nervous system macrophage': '393.2', 'Choroid plexus epithelial cell': '270.5', 'Committed oligodendrocyte precursor': '190.9', 'Ependymal cell': '257.5', 'Oligodendrocyte': '234.6', 'Oligodendrocyte precursor cell': '211.4', 'Endothelial cell': '255.0', 'Pericyte': '211.3', 'Vascular associated smooth muscle cell': '207.7', 'Fibroblast': '268.8', 'Leukocyte': '313.9', 'Basophil': '50.4', 'Eosinophil': '3.7', 'Neutrophil': '41.3', 'Classical monocyte': '65.1', 'Non-classical monocyte': '69.5', 'Intermediate monocyte': '22.6', 'T-reg': '28.1', 'GdT-cell': '2.2', 'MAIT T-cell': '32.7', 'Memory CD4 T-cell': '1.5', 'Naive CD4 T-cell': '137.4', 'Memory CD8 T-cell': '2.0', 'Naive CD8 T-cell': '112.6', 'Memory B-cell': '2.5', 'Naive B-cell': '154.1', 'Plasmacytoid DC': '33.3', 'Myeloid DC': '29.9', 'NK-cell': '128.2', 'Total PBMC': '17.8', 'Vd2 gdTCR': '25.2', 'Memory CD4 T-cell Th1\\/Th17': '126.6', 'Memory CD4 T-cell Th17': '118.3', 'Memory CD4 T-cell Th2': '127.3', 'Non-Vd2 gdTCR': '36.4', 'Memory CD4 T-cell Th1': '122.3', 'Memory CD4 T-cell TFH': '113.2', 'Terminal effector memory CD4 T-cell': '48.2', 'Central memory CD8 T-cell': '44.7', 'Effector memory CD8 T-cell': '26.0', 'Terminal effector memory CD8 T-cell': '35.9', 'Non-switched memory B-cell': '36.2', 'Plasmablast': '9.9', 'Switched memory B-cell': '41.3', 'Exhausted memory B-cell': '36.2', 'Progenitor cell': '23.5', 'Memory T-reg': '117.6', 'Naive CD4 T-cell activated': '97.0', 'Naive CD8 T-cell activated': '109.7', 'Naive T-reg': '127.7'}
|
2A7O, 2MDC, 2MDI, 2MDJ, 4FMU, 4H12, 5JJY, 5JLB, 5JLE, 5LSS, 5LSX, 5LSY, 5LSZ, 5LT6, 5LT7, 5LT8, 5V21, 5V22, 6J9J, 6VDB, 7EA8, 7EVR, 7EVS, 7LZB, 7LZD, 7LZF, 7TY2, 7TY3, 8Q5P
|
{'Adipose Tissue': 24.89976245847176, 'Adrenal Gland': 16.689887596899226, 'Bladder': 27.96761904761905, 'Blood': 15.677047362755651, 'Blood Vessel': 30.275805243445692, 'Brain': 14.591847804693414, 'Breast': 26.499324618736384, 'Cervix Uteri': 35.986315789473686, 'Colon': 26.985586649550708, 'Esophagus': 23.528862283737023, 'Fallopian Tube': 32.63444444444444, 'Heart': 8.182119744483158, 'Kidney': 13.544696629213483, 'Liver': 9.264845132743362, 'Lung': 28.56003460207613, 'Muscle': 18.875367372353672, 'Nerve': 32.93126009693054, 'Ovary': 37.002611111111115, 'Pancreas': 9.681512195121952, 'Pituitary': 23.001544169611307, 'Prostate': 26.552285714285716, 'Salivary Gland': 21.08493827160494, 'Skin': 29.357320619126583, 'Small Intestine': 26.1344385026738, 'Spleen': 24.086564315352696, 'Stomach': 18.598504178272982, 'Testis': 36.12362880886426, 'Thyroid': 37.057539050535986, 'Uterus': 38.282042253521126, 'Vagina': 28.946217948717948}
|
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0.84, 0.98, 0.7, 0.96, 0.9, 1.0, 0.99, 0.92, 1.0, 0.72, 0.99, 0.78, 1.0, 0.75, 1.0, 1.0, 0.99, 0.53, 0.52, 0.63, 0.63, 0.97, 0.96, 0.96, 0.93, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 0.97, 0.96, 0.89, 1.0, 0.93, 0.97, 0.99, 0.96, 0.99, 0.66, 0.3, 0.54, 0.86, 1.0, 0.92, 1.0, 0.96, 1.0, 0.97, 1.0, 1.0, 0.99, 1.0, 0.97, 0.96, 0.94, 0.75, 0.83, 0.77, 0.68, 0.86, 0.59, 0.38, 0.13, 0.04, 0.46, 0.19, 0.0, 0.39, 0.66, 0.02, 0.22, 0.52, 0.56, 0.09, 0.66, 0.91, 0.2, 0.72, 0.36, 0.44, 0.73, 0.87, 0.86, 0.78, 0.94, 0.87, 0.95, 0.93, 0.56, 0.72, 0.59, 0.62, 0.72, 0.93, 1.0, 1.0, 0.99, 1.0, 0.94, 1.0, 1.0, 0.99, 0.98, 1.0, 0.97, 0.84, 0.98, 0.72, 0.98, 0.89, 0.96, 0.89, 0.96, 0.95, 0.97, 0.9, 1.0, 1.0, 0.98, 1.0, 0.94, 0.94, 0.93, 0.91, 0.98, 0.96, 0.92, 0.98, 0.94, 1.0, 0.94, 1.0, 0.96, 0.41, 0.79, 0.66, 1.0, 1.0, 1.0, 0.97, 1.0, 0.78, 1.0, 0.94, 0.87, 1.0, 0.99, 0.99, 0.98, 0.99, 1.0, 1.0, 1.0, 0.98, 0.97, 0.97, 0.95, 0.77, 0.66, 0.97, 0.82, 1.0, 0.92, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 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|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 43.256431
| 0.755148
| 50
|
O43791
|
Q9H2X6
|
nan, 34133717
|
degron_data, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
HIPK2
|
MAPVYEGMASHVQVFSPHTLQSSAFCSVKKLKIEPSSNWDMTGYGSHSKVYSQSKNIPLSQPATTTVSTSLPVPNPSLPYEQTIVFPGSTGHIVVTSASSTSVTGQVLGGPHNLMRRSTVSLLDTYQKCGLKRKSEEIENTSSVQIIEEHPPMIQNNASGATVATATTSTATSKNSGSNSEGDYQLVQHEVLCSMTNTYEVLEFLGRGTFGQVVKCWKRGTNEIVAIKILKNHPSYARQGQIEVSILARLSTESADDYNFVRAYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPVLQQVATALMKLKSLGLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDTDSPYPLWRLKTPDDHEAETGIKSKEARKYIFNCLDDMAQVNMTTDLEGSDMLVEKADRREFIDLLKKMLTIDADKRITPIETLNHPFVTMTHLLDFPHSTHVKSCFQNMEICKRRVNMYDTVNQSKTPFITHVAPSTSTNLTMTFNNQLTTVHNQAPSSTSATISLANPEVSILNYPSTLYQPSAASMAAVAQRSMPLQTGTAQICARPDPFQQALIVCPPGFQGLQASPSKHAGYSVRMENAVPIVTQAPGAQPLQIQPGLLAQQAWPSGTQQILLPPAWQQLTGVATHTSVQHATVIPETMAGTQQLADWRNTHAHGSHYNPIMQQPALLTGHVTLPAAQPLNVGVAHVMRQQPTSTTSSRKSKQHQSSVRNVSTCEVSSSQAISSPQRSKRVKENTPPRCAMVHSSPACSTSVTCGWGDVASSTTRERQRQTIVIPDTPSPTVSVITISSDTDEEEEQKHAPTSTVSKQRKNVISCVTVHDSPYSDSSSNTSPYSVQQRAGHNNANAFDTKGSLENHCTGNPRTIIVPPLKTQASEVLVECDSLVPVNTSHHSSSYKSKSSSNVTSTSGHSSGSSSGAITYRQQRPGPHFQQQQPLNLSQAQQHITTDRTGSHRRQQAYITPTMAQAPYSFPHNSPSHGTVHPHLAAAAAAAHLPTQPHLYTYTAPAALGSTGTVAHLVASQGSARHTVQHTAYPASIVHQVPVSMGPRVLPSPTIHPSQYPAQFAHQTYISASPASTVYTGYPLSPAKVNQYPYI
|
Homo sapiens
|
Nucleus, PML body, Cytoplasm, Cytoplasm, Stress granule
|
Tissue enriched (brain)
|
{'Ciliated cells': '51.5', 'Basal respiratory cells': '26.7', 'Club cells': '38.0', 'Ionocytes': '43.4', 'Mucus glandular cells': '159.0', 'Serous glandular cells': '109.7', 'Gastric mucus-secreting cells': '73.7', 'Proximal enterocytes': '18.6', 'Paneth cells': '31.2', 'Distal enterocytes': '59.9', 'Intestinal goblet cells': '31.0', 'Exocrine glandular cells': '-0.565', 'Basal prostatic cells': '49.5', 'Prostatic glandular cells': '158.1', 'Breast glandular cells': '-0.296', 'Breast myoepithelial cells': '-0.514', 'Glandular and luminal cells': '38.4', 'Secretory cells': '56.7', 'Basal keratinocytes': '31.7', 'Suprabasal keratinocytes': '64.3', 'Basal squamous epithelial cells': '23.5', 'Squamous epithelial cells': '45.1', 'Alveolar cells type 1': '0.249', 'Alveolar cells type 2': '-0.142', 'Salivary duct cells': '131.3', 'Ductal cells': '0.672', 'Hepatocytes': '0.560', 'Cholangiocytes': '63.0', 'Proximal tubular cells': '0.220', 'Distal tubular cells': '15.4', 'Collecting duct cells': '62.2', 'Mesothelial cells': '-0.332', 'Sertoli cells': '0.460', 'Granulosa cells': '20.9', 'Enteroendocrine cells': '61.3', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.517', 'Excitatory neurons': '17.2', 'Inhibitory neurons': '34.7', 'Cone photoreceptor cells': '112.1', 'Rod photoreceptor cells': '63.8', 'Bipolar cells': '111.6', 'Horizontal cells': '101.3', 'Astrocytes': '78.3', 'Oligodendrocyte precursor cells': '136.3', 'Oligodendrocytes': '431.6', 'Microglial cells': '47.4', 'Muller glia cells': '65.4', 'Schwann cells': '0.132', 'Spermatogonia': '0.618', 'Spermatocytes': '0.189', 'Early spermatids': '-0.485', 'Late spermatids': '-0.574', 'Oocytes': '5.9', 'Cytotrophoblasts': '8.1', 'Syncytiotrophoblasts': '9.0', 'Extravillous trophoblasts': '1.3', 'Endothelial cells': '77.4', 'Lymphatic endothelial cells': '25.1', 'Cardiomyocytes': '0.634', 'Skeletal myocytes': '-0.202', 'Smooth muscle cells': '70.5', 'Adipocytes': '102.6', 'Melanocytes': '-0.053', 'Fibroblasts': '41.6', 'Peritubular cells': '0.493', 'Endometrial stromal cells': '11.5', 'Ovarian stromal cells': '12.6', 'Undifferentiated cells': '26.1', 'T-cells': '34.4', 'B-cells': '54.7', 'Plasma cells': '136.4', 'Nk-cells': '119.4', 'Granulocytes': '70.6', 'Monocytes': '131.8', 'Macrophages': '55.8', 'Hofbauer cells': '19.0', 'Kupffer cells': '131.5', 'Dendritic cells': '31.9', 'Langerhans cells': '-0.213', 'Erythroid cells': '-0.130', 'Adipocytes (Subcutaneous)': '0.580', 'Adipocytes (Visceral)': '0.469', 'Breast glandular cells (progenitors)': '-0.357', 'Adipocytes (Breast)': '0.581', 'Colon enterocytes': '0.164', 'Colon enteroendocrine cells': '0.274', 'Enteric glia cells': '0.269', 'Mitotic cells (Colon)': '0.249', 'Mitotic cells (Heart)': '0.450', 'Podocytes': '0.051', 'Ascending Loop of Henle cells': '0.226', 'Intercalated cells': '0.002', 'Cholangiocyte': '0.199', 'NK-cells (Liver)': '-0.383', 'Respiratory ciliated cells': '-0.006', 'Mitotic cells (Lung)': '-0.227', 'NK-cells (Lung)': '0.281', 'B-cells (Lung)': '0.077', 'Alpha cells': '0.381', 'Beta cells': '0.273', 'Prostate glandular cells': '0.494', 'Prostate basal glandular cells': '0.296', 'Urothelial cells': '-0.073', 'Keratinocyte (other)': '-0.583', 'Keratinocyte (granular)': '-0.201', 'Hair cortex cells': '0.382', 'Inner root sheath cells': '0.420', 'Outer root sheath cells': '0.373', 'Sebaceous gland cells': '0.307', 'Eccrine sweat gland cells': '0.466', 'Adipocytes (Skin)': '0.534', 'Mitotic cells (Skin)': '0.076', 'Parietal cells': '0.520', 'Chief cells': '0.517', 'Gastric mucous cells': '0.636', 'Gastric enteroendocrine cells': '0.559', 'Mitotic cells (Stomach)': '0.407', 'Parafollicular cells': '0.117', 'Thyroid glandular cells': '0.340', 'Mitotic cells (Thyroid)': '-0.114', 'Adrenal cortex cells': '0.684', 'Adrenal medulla cells': '0.020', 'Mitotic cells (Adrenal gland)': '0.351', 'Minor salivary glandular cells': '0.743', 'Minor salivary gland ductal cells': '0.316', 'Minor salivary gland basal cells': '-0.051', 'Mitotic cells (Minor salivary gland)': '0.017', 'Adipocytes (Minor salivary gland)': '0.009', 'Somatotropes': '0.264', 'Lactotropes': '-0.064', 'Gonadotropes': '-0.053', 'Corticotropes': '-0.258', 'Thyrotropes': '0.021', 'Undifferentiated cells (Pituitary gland)': '0.153', 'Mitotic cells (Spleen)': '0.049', 'Platelets': '0.032', 'Erythrocytes': '-0.211', 'Hematopoietic stem cells': '-0.061', 'B-cells (Spleen)': '0.080', 'NK-cells (Spleen)': '0.000', 'Amygdala excitatory': '48.6', 'Cerebellar inhibitory': '288.2', 'Cge interneuron': '102.8', 'Deep-layer corticothalamic and 6b': '51.4', 'Deep-layer intratelencephalic': '49.6', 'Deep-layer near-projecting': '70.0', 'Eccentric medium spiny neuron': '84.2', 'Hippocampal ca1-3': '23.6', 'Hippocampal ca4': '47.1', 'Hippocampal dentate gyrus': '47.5', 'Lamp5-lhx6 and chandelier': '45.8', 'Lower rhombic lip': '39.3', 'Mammillary body': '105.9', 'Medium spiny neuron': '43.0', 'Mge interneuron': '43.5', 'Midbrain-derived inhibitory': '110.4', 'Miscellaneous': '29.5', 'Splatter': '93.4', 'Thalamic excitatory': '66.9', 'Upper rhombic lip': '43.8', 'Upper-layer intratelencephalic': '39.4', 'Astrocyte': '220.1', 'Bergmann glia': '100.3', 'Central nervous system macrophage': '143.2', 'Choroid plexus epithelial cell': '108.7', 'Committed oligodendrocyte precursor': '750.3', 'Ependymal cell': '156.3', 'Oligodendrocyte': '747.0', 'Oligodendrocyte precursor cell': '266.3', 'Endothelial cell': '158.6', 'Pericyte': '50.0', 'Vascular associated smooth muscle cell': '303.8', 'Fibroblast': '53.7', 'Leukocyte': '192.3', 'Basophil': '128.5', 'Eosinophil': '3.5', 'Neutrophil': '9.0', 'Classical monocyte': '21.5', 'Non-classical monocyte': '26.3', 'Intermediate monocyte': '14.7', 'T-reg': '4.8', 'GdT-cell': '0.2', 'MAIT T-cell': '9.4', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '38.9', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '25.4', 'Memory B-cell': '0.6', 'Naive B-cell': '7.2', 'Plasmacytoid DC': '1.6', 'Myeloid DC': '10.9', 'NK-cell': '87.7', 'Total PBMC': '11.3', 'Vd2 gdTCR': '4.9', 'Memory CD4 T-cell Th1\\/Th17': '27.4', 'Memory CD4 T-cell Th17': '27.2', 'Memory CD4 T-cell Th2': '28.0', 'Non-Vd2 gdTCR': '16.5', 'Memory CD4 T-cell Th1': '21.9', 'Memory CD4 T-cell TFH': '31.6', 'Terminal effector memory CD4 T-cell': '6.6', 'Central memory CD8 T-cell': '7.9', 'Effector memory CD8 T-cell': '3.4', 'Terminal effector memory CD8 T-cell': '5.9', 'Non-switched memory B-cell': '9.2', 'Plasmablast': '40.8', 'Switched memory B-cell': '31.0', 'Exhausted memory B-cell': '17.0', 'Progenitor cell': '6.6', 'Memory T-reg': '13.1', 'Naive CD4 T-cell activated': '20.5', 'Naive CD8 T-cell activated': '20.2', 'Naive T-reg': '24.4'}
|
6P5S, 7NCF
|
{'Adipose Tissue': 20.800302325581395, 'Adrenal Gland': 14.048740310077518, 'Bladder': 11.928190476190476, 'Blood': 9.99436856835307, 'Blood Vessel': 17.432044194756553, 'Brain': 75.61005715367146, 'Breast': 18.32059477124183, 'Cervix Uteri': 9.806473684210529, 'Colon': 6.989481129653402, 'Esophagus': 9.992020069204152, 'Fallopian Tube': 12.249666666666666, 'Heart': 16.235156910569106, 'Kidney': 20.281303370786517, 'Liver': 11.057969026548673, 'Lung': 20.937351211072667, 'Muscle': 18.191046077210466, 'Nerve': 18.438852988691437, 'Ovary': 10.40152222222222, 'Pancreas': 5.706670731707317, 'Pituitary': 18.461067137809188, 'Prostate': 14.681824489795918, 'Salivary Gland': 20.40370987654321, 'Skin': 13.474187949143174, 'Small Intestine': 11.620267379679143, 'Spleen': 10.87330705394191, 'Stomach': 14.285933147632312, 'Testis': 2.8169529085872576, 'Thyroid': 20.35366615620214, 'Uterus': 13.548521126760564, 'Vagina': 10.53401923076923}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
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0.99, 0.99, 0.96, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.9, 1.0, 0.9, 1.0, 0.93, 1.0, 1.0, 0.88, 1.0, 0.82, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 0.75, 0.84, 0.44, 0.84, 0.99, 0.95, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.95, 0.8, 0.96, 0.87, 0.95, 1.0, 0.94, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.96, 1.0, 1.0, 0.99, 1.0, 0.99, 0.81, 0.44, 0.62, 0.86, 0.88, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 0.98, 0.89, 0.86, 0.94, 0.87, 0.92, 0.89, 0.94, 0.94, 0.95, 0.92, 0.95, 0.87, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 1.0, 0.92, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.9, 1.0, 0.87, 0.78, 0.8, 0.84, 0.94, 0.95, 0.97, 1.0, 0.85, 0.99, 0.84, 0.98, 0.86, 0.99, 1.0, 0.96, 0.95, 0.96, 0.9, 0.95, 0.93, 0.96, 1.0, 1.0, 0.97, 0.98, 0.95, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.89, 0.97, 0.84, 0.85, 0.82, 0.84, 0.88, 0.9, 0.96, 0.88, 0.95, 0.86, 0.85, 0.93, 0.74, 0.85, 0.68, 0.67, 0.82, 0.76, 0.79, 0.65, 0.85, 0.86, 0.93, 0.77, 0.98, 0.78, 0.95, 0.72, 0.98, 0.95, 0.98, 1.0, 1.0, 0.97, 1.0, 0.82, 0.99, 0.85, 0.88, 0.93, 0.77, 0.9, 0.75, 0.83, 0.73, 0.76, 0.75, 0.71, 0.84, 0.84, 0.94, 0.89, 0.97, 0.69, 0.73, 0.46, 0.99, 0.99, 0.99, 1.0, 0.99, 1.0, 1.0, 0.97, 1.0, 0.96, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.9, 0.95, 0.91, 0.95, 0.85, 0.89, 0.86, 0.9, 0.92, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 0.99, 0.97, 0.91, 0.95, 0.93, 1.0, 1.0, 0.94, 1.0, 0.94, 0.99, 1.0, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 0.94, 1.0, 0.96, 1.0, 0.99, 1.0, 0.95, 1.0, 0.92, 1.0, 0.93, 0.94, 0.93, 0.95, 0.93, 1.0, 0.95, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.98, 0.97, 0.94, 0.98, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.76, 0.93, 0.74, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.68, 1.0, 0.58, 0.96, 0.71, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.85, 0.98, 0.96, 0.99, 0.98, 0.99, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.77, 0.77, 0.34, 0.83, 0.81, 1.0, 1.0, 0.91, 1.0, 0.93, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.86, 0.95, 0.77, 0.95, 0.99, 0.97, 0.98, 1.0, 0.99, 1.0, 0.92, 0.98, 0.9, 0.94, 0.91, 0.95, 0.94, 0.97, 0.93, 1.0, 0.99, 1.0, 1.0, 1.0, 0.97, 1.0, 0.86, 1.0, 0.8, 1.0, 0.91, 0.96, 1.0, 0.97, 1.0, 0.98, 0.99, 0.99, 0.92, 1.0, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 0.85, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 52.903456
| 0.725977
| 334
|
O43791
|
Q9H5J0
|
nan, 31911863, 28805821
|
degron_data, UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
ZBTB3
|
MLREFSKWGVEASPGKAWERKRSLLRGAVGRYRGATGGDLFWAPFPSWGTMEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDKRDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSPTVRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFSSGISAVSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQAPAPAEAELVQVKVEAIVISDEETDVSDEQPQGPERAFPSGGAVYGAQPSQPEAFEDPGAAGLEEVGPSDHFLPTDPHLPYHLLPGAGQYHRGLVTSPLPAPASLHEPLYLSSEYEAAPGSFGVFTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKRSKPDPEVGPLLGVQPLPGSPTADRQSSSGGGPPKDFVLAPKTNI
|
Homo sapiens
|
Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '2.9', 'Basal respiratory cells': '1.0', 'Club cells': '1.3', 'Ionocytes': '0.7', 'Mucus glandular cells': '1.5', 'Serous glandular cells': '1.2', 'Gastric mucus-secreting cells': '2.9', 'Proximal enterocytes': '2.4', 'Paneth cells': '3.4', 'Distal enterocytes': '2.4', 'Intestinal goblet cells': '3.7', 'Exocrine glandular cells': '-0.495', 'Basal prostatic cells': '2.9', 'Prostatic glandular cells': '1.9', 'Breast glandular cells': '0.407', 'Breast myoepithelial cells': '0.034', 'Glandular and luminal cells': '1.4', 'Secretory cells': '2.0', 'Basal keratinocytes': '1.0', 'Suprabasal keratinocytes': '1.2', 'Basal squamous epithelial cells': '1.6', 'Squamous epithelial cells': '0.8', 'Alveolar cells type 1': '-0.086', 'Alveolar cells type 2': '0.012', 'Salivary duct cells': '1.4', 'Ductal cells': '0.487', 'Hepatocytes': '0.353', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.133', 'Distal tubular cells': '15.4', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.275', 'Sertoli cells': '-0.265', 'Granulosa cells': '1.7', 'Enteroendocrine cells': '1.1', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.365', 'Excitatory neurons': '0.5', 'Inhibitory neurons': '0.5', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '5.6', 'Bipolar cells': '1.6', 'Horizontal cells': '1.3', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '2.1', 'Microglial cells': '0.0', 'Muller glia cells': '1.9', 'Schwann cells': '0.061', 'Spermatogonia': '-0.001', 'Spermatocytes': '0.255', 'Early spermatids': '0.389', 'Late spermatids': '0.429', 'Oocytes': '1.5', 'Cytotrophoblasts': '4.3', 'Syncytiotrophoblasts': '3.4', 'Extravillous trophoblasts': '2.5', 'Endothelial cells': '1.4', 'Lymphatic endothelial cells': '0.5', 'Cardiomyocytes': '0.655', 'Skeletal myocytes': '-0.302', 'Smooth muscle cells': '1.8', 'Adipocytes': '1.2', 'Melanocytes': '0.070', 'Fibroblasts': '1.7', 'Peritubular cells': '-0.251', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '2.4', 'Undifferentiated cells': '2.7', 'T-cells': '1.7', 'B-cells': '1.9', 'Plasma cells': '1.2', 'Nk-cells': '1.8', 'Granulocytes': '1.2', 'Monocytes': '1.3', 'Macrophages': '1.4', 'Hofbauer cells': '2.0', 'Kupffer cells': '3.2', 'Dendritic cells': '0.8', 'Langerhans cells': '0.250', 'Erythroid cells': '-0.049', 'Adipocytes (Subcutaneous)': '0.307', 'Adipocytes (Visceral)': '-0.072', 'Breast glandular cells (progenitors)': '0.250', 'Adipocytes (Breast)': '-0.082', 'Colon enterocytes': '0.098', 'Colon enteroendocrine cells': '0.042', 'Enteric glia cells': '-0.308', 'Mitotic cells (Colon)': '0.023', 'Mitotic cells (Heart)': '0.465', 'Podocytes': '-0.303', 'Ascending Loop of Henle cells': '0.553', 'Intercalated cells': '-0.099', 'Cholangiocyte': '0.088', 'NK-cells (Liver)': '-0.071', 'Respiratory ciliated cells': '0.086', 'Mitotic cells (Lung)': '0.197', 'NK-cells (Lung)': '-0.092', 'B-cells (Lung)': '-0.151', 'Alpha cells': '0.365', 'Beta cells': '0.292', 'Prostate glandular cells': '0.150', 'Prostate basal glandular cells': '0.404', 'Urothelial cells': '0.236', 'Keratinocyte (other)': '0.316', 'Keratinocyte (granular)': '0.193', 'Hair cortex cells': '-0.293', 'Inner root sheath cells': '-0.246', 'Outer root sheath cells': '-0.172', 'Sebaceous gland cells': '0.083', 'Eccrine sweat gland cells': '-0.250', 'Adipocytes (Skin)': '-0.149', 'Mitotic cells (Skin)': '0.148', 'Parietal cells': '0.438', 'Chief cells': '0.260', 'Gastric mucous cells': '0.452', 'Gastric enteroendocrine cells': '0.286', 'Mitotic cells (Stomach)': '0.318', 'Parafollicular cells': '-0.028', 'Thyroid glandular cells': '0.211', 'Mitotic cells (Thyroid)': '0.047', 'Adrenal cortex cells': '0.509', 'Adrenal medulla cells': '0.032', 'Mitotic cells (Adrenal gland)': '0.477', 'Minor salivary glandular cells': '0.412', 'Minor salivary gland ductal cells': '0.256', 'Minor salivary gland basal cells': '0.013', 'Mitotic cells (Minor salivary gland)': '0.166', 'Adipocytes (Minor salivary gland)': '0.008', 'Somatotropes': '0.077', 'Lactotropes': '0.041', 'Gonadotropes': '-0.024', 'Corticotropes': '-0.014', 'Thyrotropes': '0.115', 'Undifferentiated cells (Pituitary gland)': '0.214', 'Mitotic cells (Spleen)': '-0.174', 'Platelets': '0.064', 'Erythrocytes': '-0.122', 'Hematopoietic stem cells': '-0.068', 'B-cells (Spleen)': '0.295', 'NK-cells (Spleen)': '0.256', 'Amygdala excitatory': '2.2', 'Cerebellar inhibitory': '2.7', 'Cge interneuron': '2.4', 'Deep-layer corticothalamic and 6b': '2.6', 'Deep-layer intratelencephalic': '2.4', 'Deep-layer near-projecting': '2.1', 'Eccentric medium spiny neuron': '2.8', 'Hippocampal ca1-3': '2.2', 'Hippocampal ca4': '1.7', 'Hippocampal dentate gyrus': '2.5', 'Lamp5-lhx6 and chandelier': '2.3', 'Lower rhombic lip': '1.9', 'Mammillary body': '2.0', 'Medium spiny neuron': '2.3', 'Mge interneuron': '1.8', 'Midbrain-derived inhibitory': '2.2', 'Miscellaneous': '2.6', 'Splatter': '2.0', 'Thalamic excitatory': '2.5', 'Upper rhombic lip': '2.6', 'Upper-layer intratelencephalic': '2.4', 'Astrocyte': '4.4', 'Bergmann glia': '4.4', 'Central nervous system macrophage': '2.4', 'Choroid plexus epithelial cell': '3.3', 'Committed oligodendrocyte precursor': '6.3', 'Ependymal cell': '2.3', 'Oligodendrocyte': '9.0', 'Oligodendrocyte precursor cell': '2.7', 'Endothelial cell': '2.2', 'Pericyte': '3.1', 'Vascular associated smooth muscle cell': '0.7', 'Fibroblast': '2.2', 'Leukocyte': '3.8', 'Basophil': '9.7', 'Eosinophil': '9.4', 'Neutrophil': '8.5', 'Classical monocyte': '2.3', 'Non-classical monocyte': '4.9', 'Intermediate monocyte': '8.5', 'T-reg': '5.2', 'GdT-cell': '4.0', 'MAIT T-cell': '5.1', 'Memory CD4 T-cell': '4.1', 'Naive CD4 T-cell': '3.5', 'Memory CD8 T-cell': '4.9', 'Naive CD8 T-cell': '3.5', 'Memory B-cell': '4.0', 'Naive B-cell': '3.9', 'Plasmacytoid DC': '3.8', 'Myeloid DC': '5.3', 'NK-cell': '4.2', 'Total PBMC': '7.0', 'Vd2 gdTCR': '6.6', 'Memory CD4 T-cell Th1\\/Th17': '2.4', 'Memory CD4 T-cell Th17': '3.6', 'Memory CD4 T-cell Th2': '3.5', 'Non-Vd2 gdTCR': '7.4', 'Memory CD4 T-cell Th1': '2.7', 'Memory CD4 T-cell TFH': '3.6', 'Terminal effector memory CD4 T-cell': '11.4', 'Central memory CD8 T-cell': '6.7', 'Effector memory CD8 T-cell': '5.6', 'Terminal effector memory CD8 T-cell': '5.3', 'Non-switched memory B-cell': '7.2', 'Plasmablast': '5.3', 'Switched memory B-cell': '7.0', 'Exhausted memory B-cell': '7.5', 'Progenitor cell': '10.0', 'Memory T-reg': '5.5', 'Naive CD4 T-cell activated': '5.1', 'Naive CD8 T-cell activated': '5.5', 'Naive T-reg': '4.1'}
| null |
{'Adipose Tissue': 1.7701478405315614, 'Adrenal Gland': 2.189137596899225, 'Bladder': 2.834904761904762, 'Blood': 2.0639881808396123, 'Blood Vessel': 1.7171888389513108, 'Brain': 1.9917445495836483, 'Breast': 2.0557588235294117, 'Cervix Uteri': 2.802, 'Colon': 2.5642101412066753, 'Esophagus': 2.7207515570934255, 'Fallopian Tube': 4.146, 'Heart': 1.1703019860627175, 'Kidney': 1.6736786516853934, 'Liver': 1.4477673451327435, 'Lung': 2.1845475778546715, 'Muscle': 1.0749956413449564, 'Nerve': 3.190122294022617, 'Ovary': 2.6027766666666667, 'Pancreas': 1.6057423780487805, 'Pituitary': 2.2956618374558304, 'Prostate': 2.929338367346938, 'Salivary Gland': 2.5570203703703704, 'Skin': 3.443136097291321, 'Small Intestine': 3.05648128342246, 'Spleen': 3.7933692946058097, 'Stomach': 3.2858311977715875, 'Testis': 6.955185595567867, 'Thyroid': 3.487104441041348, 'Uterus': 3.7173732394366192, 'Vagina': 2.6184141025641026}
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|
[30.3, 29.81, 29.87, 33.23, 35.14, 35.75, 33.53, 33.99, 34.24, 39.23, 30.25, 31.71, 32.97, 37.19, 35.51, 35.54, 35.41, 36.16, 37.51, 37.36, 39.09, 40.66, 40.39, 38.22, 40.69, 41.16, 39.33, 43.69, 38.34, 35.08, 36.72, 31.96, 32.66, 34.95, 35.5, 41.91, 36.79, 39.01, 39.07, 40.67, 40.23, 34.72, 39.93, 42.11, 37.9, 42.06, 44.69, 38.49, 41.42, 55.94, 49.61, 56.57, 66.8, 72.63, 83.24, 82.84, 81.34, 84.66, 86.43, 89.11, 89.16, 90.31, 89.17, 91.06, 91.78, 90.5, 89.15, 92.03, 89.35, 85.64, 82.26, 79.34, 80.84, 87.86, 85.73, 88.16, 90.21, 91.73, 90.92, 93.16, 87.12, 85.65, 92.59, 91.25, 94.05, 92.66, 93.85, 91.26, 89.89, 88.96, 93.21, 93.77, 91.64, 91.65, 92.42, 93.61, 91.76, 91.48, 91.55, 87.65, 85.6, 84.15, 83.72, 78.57, 68.56, 63.89, 59.11, 57.16, 51.18, 52.83, 54.75, 68.25, 79.05, 86.04, 86.45, 88.75, 84.06, 84.77, 83.47, 84.23, 93.04, 93.79, 93.93, 94.18, 94.99, 95.71, 94.58, 94.07, 95.35, 94.89, 93.02, 93.46, 93.73, 93.5, 89.45, 85.45, 85.0, 88.09, 85.27, 82.69, 71.06, 69.07, 78.53, 88.02, 90.92, 92.13, 93.42, 94.01, 94.25, 94.85, 95.11, 95.88, 95.52, 95.54, 94.91, 94.86, 93.99, 93.51, 92.18, 90.46, 92.27, 93.3, 91.78, 90.6, 92.46, 93.14, 91.24, 89.22, 91.67, 93.05, 90.54, 88.67, 90.84, 91.92, 89.57, 89.16, 88.24, 85.11, 81.86, 78.88, 73.64, 69.88, 63.28, 60.35, 58.0, 58.43, 55.89, 55.95, 47.06, 39.04, 39.52, 33.79, 35.41, 42.77, 34.78, 38.24, 39.71, 39.99, 38.44, 44.68, 41.23, 34.44, 42.02, 41.43, 37.17, 38.71, 36.8, 36.55, 35.84, 39.63, 36.97, 37.54, 35.56, 41.58, 35.9, 29.66, 39.06, 32.5, 39.75, 29.86, 36.16, 31.82, 27.77, 34.87, 33.81, 31.65, 38.45, 33.9, 41.68, 33.17, 48.83, 39.55, 43.73, 55.99, 45.25, 38.13, 57.5, 48.07, 45.52, 47.98, 39.7, 49.9, 41.9, 44.22, 44.44, 44.64, 43.69, 47.6, 40.07, 54.18, 42.35, 47.84, 39.3, 39.36, 48.25, 38.22, 39.72, 35.04, 44.22, 40.39, 37.34, 52.99, 44.42, 38.14, 46.62, 38.18, 40.16, 39.27, 36.38, 36.8, 35.3, 47.1, 35.48, 43.57, 40.69, 42.7, 37.27, 39.89, 30.38, 35.38, 32.18, 35.16, 33.72, 32.22, 35.91, 37.56, 33.93, 38.68, 35.25, 30.42, 36.15, 31.36, 38.98, 37.05, 35.32, 39.88, 37.3, 27.68, 38.56, 32.21, 39.24, 34.86, 41.63, 35.32, 34.12, 24.18, 33.74, 26.28, 33.31, 31.94, 38.6, 34.02, 36.75, 41.34, 35.57, 39.47, 41.37, 34.39, 41.54, 34.83, 31.37, 38.44, 50.73, 39.15, 38.18, 42.2, 40.86, 47.05, 39.09, 43.11, 41.31, 40.54, 44.95, 41.46, 47.44, 42.72, 46.56, 36.21, 40.2, 40.74, 38.91, 39.62, 38.22, 37.51, 38.65, 41.48, 40.87, 41.66, 44.88, 52.82, 46.26, 48.23, 39.5, 44.58, 39.0, 46.13, 38.87, 38.47, 39.7, 32.88, 34.36, 36.07, 35.04, 45.98, 42.83, 39.64, 40.86, 40.98, 41.57, 40.32, 40.27, 35.48, 33.12, 36.65, 37.95, 35.97, 36.5, 36.62, 38.15, 32.7, 36.55, 38.97, 36.59, 34.9, 36.73, 39.84, 34.26, 36.31, 33.06, 33.72, 33.76, 34.78, 32.55, 39.55, 31.47, 36.49, 29.43, 37.7, 35.57, 43.24, 33.65, 39.65, 41.38, 38.48, 44.58, 39.3, 40.86, 41.27, 43.51, 48.39, 41.09, 44.35, 38.98, 35.45, 38.57, 38.99, 37.87, 34.04, 41.38, 37.12, 37.79, 38.82, 35.51, 38.86, 36.58, 34.37, 43.03, 41.59, 39.88, 41.91, 44.71, 38.2, 36.74, 43.12, 40.48, 44.16, 42.6, 41.06, 41.99, 43.25, 45.54, 44.74, 39.82, 40.76, 36.14, 38.4, 36.53, 37.59, 31.92, 40.94, 32.8, 35.04, 37.31, 31.7, 42.62, 36.97, 48.88, 41.45, 40.63, 40.31, 45.38, 42.11, 40.09, 38.73, 39.63, 41.98, 42.95, 51.01, 52.35, 67.55, 79.68, 81.61, 84.62, 88.72, 85.84, 85.58, 88.48, 85.54, 85.1, 84.44, 81.62, 79.37, 73.17, 79.84, 72.48, 78.95, 85.1, 81.53, 78.59, 83.75, 81.8, 81.8, 81.48, 83.07, 80.66, 76.33, 79.94, 82.23, 78.62, 80.39, 84.37, 82.8, 86.09, 83.96, 88.46, 86.6, 85.95, 85.49, 79.83, 80.24, 77.53, 79.1, 76.79, 79.92, 82.98, 78.09, 79.34, 83.71, 81.57, 80.32, 82.51, 84.68, 84.94, 72.6, 73.04, 69.65, 61.6, 59.1, 58.47, 54.38, 50.56, 38.97, 45.17, 35.31, 52.33, 41.6, 42.52, 38.1, 39.74, 38.94, 41.81, 35.23, 42.98, 39.98, 37.19, 39.71, 38.91, 37.28, 41.67, 42.73, 35.46, 45.95, 44.11, 42.69, 47.39, 39.94, 43.77, 44.65, 40.88, 37.48, 37.98, 46.19, 44.94, 43.19, 42.37, 40.35, 43.63, 38.27, 44.92, 50.68, 42.69, 37.38, 43.14, 50.71]
|
[0.7, 0.82, 0.9, 0.46, 0.64, 0.63, 0.69, 0.8, 0.36, 0.75, 0.94, 0.8, 0.78, 0.81, 0.55, 0.75, 0.57, 0.58, 0.71, 0.76, 0.7, 0.35, 0.67, 0.75, 0.67, 0.72, 0.76, 0.84, 0.58, 0.87, 0.97, 0.96, 0.99, 0.79, 0.99, 0.87, 1.0, 0.72, 0.91, 0.63, 0.63, 0.69, 0.71, 0.95, 0.9, 0.99, 0.98, 0.88, 0.73, 0.82, 0.56, 0.77, 0.63, 0.63, 0.64, 0.36, 0.14, 0.64, 0.59, 0.39, 0.11, 0.57, 0.44, 0.18, 0.48, 0.47, 0.28, 0.19, 0.67, 0.77, 0.32, 0.59, 0.73, 0.21, 0.39, 0.01, 0.19, 0.0, 0.2, 0.01, 0.51, 0.92, 0.37, 0.72, 0.19, 0.44, 0.0, 0.11, 0.21, 0.69, 0.1, 0.0, 0.24, 0.75, 0.22, 0.01, 0.35, 0.2, 0.0, 0.51, 0.55, 0.07, 0.15, 0.66, 0.52, 0.37, 0.91, 0.29, 0.88, 0.97, 0.85, 0.34, 0.37, 0.02, 0.06, 0.05, 0.3, 0.44, 0.93, 0.5, 0.0, 0.31, 0.15, 0.55, 0.0, 0.01, 0.2, 0.17, 0.0, 0.03, 0.44, 0.06, 0.01, 0.01, 0.26, 0.06, 0.41, 0.04, 0.33, 0.07, 0.53, 0.94, 0.86, 0.12, 0.48, 0.18, 0.49, 0.31, 0.0, 0.17, 0.4, 0.0, 0.0, 0.37, 0.21, 0.0, 0.15, 0.05, 0.44, 0.51, 0.04, 0.11, 0.53, 0.21, 0.01, 0.53, 0.62, 0.24, 0.24, 0.6, 0.54, 0.56, 0.49, 0.62, 0.56, 0.48, 0.48, 0.69, 0.5, 0.55, 0.63, 0.68, 0.61, 0.71, 0.58, 0.62, 0.82, 0.74, 0.84, 0.93, 0.94, 0.82, 0.77, 0.88, 0.82, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 0.96, 0.94, 0.96, 0.99, 0.98, 1.0, 0.98, 1.0, 1.0, 0.98, 0.98, 0.95, 1.0, 0.99, 0.98, 0.99, 0.97, 0.96, 0.99, 0.97, 0.99, 0.99, 0.99, 0.93, 0.98, 0.89, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.95, 0.95, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.98, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 0.95, 0.97, 0.91, 0.89, 0.87, 0.94, 0.83, 1.0, 0.83, 0.88, 0.92, 0.85, 0.96, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.98, 0.96, 0.97, 0.96, 0.85, 1.0, 0.88, 1.0, 1.0, 1.0, 0.97, 1.0, 0.91, 1.0, 1.0, 0.92, 0.94, 0.97, 0.86, 0.99, 0.95, 0.99, 1.0, 0.99, 1.0, 1.0, 0.97, 0.97, 0.98, 0.9, 0.91, 0.96, 0.85, 0.97, 0.86, 0.9, 0.9, 0.88, 0.94, 0.95, 0.99, 1.0, 1.0, 0.96, 1.0, 0.96, 1.0, 0.95, 0.94, 0.98, 0.94, 0.92, 0.98, 0.93, 0.98, 0.95, 0.89, 0.91, 0.92, 0.34, 0.5, 0.58, 0.13, 0.74, 0.24, 0.72, 0.29, 0.36, 0.28, 0.79, 0.6, 0.72, 0.76, 0.68, 0.77, 0.83, 0.77, 0.78, 0.82, 0.68, 0.83, 0.89, 0.72, 0.93, 0.86, 0.92, 0.97, 0.96, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.87, 1.0, 0.96, 1.0, 0.98, 0.93, 0.99, 0.85, 0.98, 0.91, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.85, 1.0, 0.84, 1.0, 0.92, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 0.94, 0.99, 0.93, 1.0, 0.95, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.9, 0.8, 0.76, 0.82, 0.86, 0.97, 0.67, 0.85, 0.89, 0.82, 0.96, 0.76, 0.82, 0.95, 0.94, 0.91, 0.93, 0.49, 0.81, 0.86, 0.84, 0.8, 0.89, 0.47, 0.19, 0.43, 0.05, 0.95, 0.69, 0.4, 0.61, 0.57, 0.66, 0.2, 0.89, 0.11, 0.57, 0.16, 0.09, 0.21, 0.71, 0.26, 0.16, 0.35, 0.24, 0.67, 0.38, 0.55, 0.78, 0.57, 0.54, 0.77, 0.25, 0.52, 0.0, 0.87, 0.39, 0.48, 0.63, 0.62, 0.33, 0.16, 0.32, 0.33, 0.33, 0.56, 0.19, 0.13, 0.36, 0.55, 0.16, 0.15, 0.37, 0.79, 0.7, 0.12, 0.63, 0.73, 0.27, 0.43, 0.54, 0.64, 0.79, 0.6, 0.83, 0.88, 0.92, 0.87, 0.99, 0.98, 0.73, 0.88, 0.91, 0.93, 0.89, 1.0, 0.96, 0.98, 0.99, 0.98, 0.96, 0.99, 0.99, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 54.638746
| 0.730871
| 1,341
|
O43791
|
Q9H7N4
|
nan, 25278611
|
degron_data, DegPred
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
SCAF1
|
MEEEDESRGKTEESGEDRGDGPPDRDPTLSPSAFILRAIQQAVGSSLQGDLPNDKDGSRCHGLRWRRCRSPRSEPRSQESGGTDTATVLDMATDSFLAGLVSVLDPPDTWVPSRLDLRPGESEDMLELVAEVRIGDRDPIPLPVPSLLPRLRAWRTGKTVSPQSNSSRPTCARHLTLGTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRKPPSSLGMTPAPVPTSLGLPPGPSSYLLPGSLPLGGCGSTPPTPTGLAATSDKREGSSSSEGRGDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKAVHKICHSKSGEINPVKVSNLVRAYVQRYRYFRKHGRKPGDPPGPPRPPKEPGPPDKGGPGLPLPPL
|
Homo sapiens
|
Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '20.9', 'Basal respiratory cells': '11.5', 'Club cells': '14.5', 'Ionocytes': '10.3', 'Mucus glandular cells': '11.9', 'Serous glandular cells': '16.0', 'Gastric mucus-secreting cells': '17.7', 'Proximal enterocytes': '21.7', 'Paneth cells': '19.9', 'Distal enterocytes': '24.0', 'Intestinal goblet cells': '19.7', 'Exocrine glandular cells': '-0.733', 'Basal prostatic cells': '15.4', 'Prostatic glandular cells': '15.2', 'Breast glandular cells': '0.523', 'Breast myoepithelial cells': '0.470', 'Glandular and luminal cells': '19.8', 'Secretory cells': '21.4', 'Basal keratinocytes': '13.6', 'Suprabasal keratinocytes': '16.1', 'Basal squamous epithelial cells': '21.3', 'Squamous epithelial cells': '22.9', 'Alveolar cells type 1': '0.229', 'Alveolar cells type 2': '-0.121', 'Salivary duct cells': '14.8', 'Ductal cells': '0.613', 'Hepatocytes': '0.405', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.068', 'Distal tubular cells': '6.1', 'Collecting duct cells': '19.4', 'Mesothelial cells': '0.448', 'Sertoli cells': '0.194', 'Granulosa cells': '16.5', 'Enteroendocrine cells': '17.7', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '0.013', 'Excitatory neurons': '6.8', 'Inhibitory neurons': '8.0', 'Cone photoreceptor cells': '6.8', 'Rod photoreceptor cells': '6.0', 'Bipolar cells': '11.5', 'Horizontal cells': '8.8', 'Astrocytes': '7.4', 'Oligodendrocyte precursor cells': '8.5', 'Oligodendrocytes': '8.1', 'Microglial cells': '8.1', 'Muller glia cells': '10.1', 'Schwann cells': '0.053', 'Spermatogonia': '0.332', 'Spermatocytes': '0.256', 'Early spermatids': '0.151', 'Late spermatids': '0.077', 'Oocytes': '16.2', 'Cytotrophoblasts': '14.7', 'Syncytiotrophoblasts': '21.2', 'Extravillous trophoblasts': '13.8', 'Endothelial cells': '13.6', 'Lymphatic endothelial cells': '14.3', 'Cardiomyocytes': '0.605', 'Skeletal myocytes': '-0.253', 'Smooth muscle cells': '16.3', 'Adipocytes': '15.6', 'Melanocytes': '0.120', 'Fibroblasts': '14.5', 'Peritubular cells': '-0.017', 'Endometrial stromal cells': '13.1', 'Ovarian stromal cells': '15.3', 'Undifferentiated cells': '16.2', 'T-cells': '13.2', 'B-cells': '15.0', 'Plasma cells': '16.5', 'Nk-cells': '10.6', 'Granulocytes': '13.8', 'Monocytes': '13.2', 'Macrophages': '15.0', 'Hofbauer cells': '13.8', 'Kupffer cells': '8.1', 'Dendritic cells': '15.1', 'Langerhans cells': '0.251', 'Erythroid cells': '-0.072', 'Adipocytes (Subcutaneous)': '0.022', 'Adipocytes (Visceral)': '-0.028', 'Breast glandular cells (progenitors)': '0.405', 'Adipocytes (Breast)': '-0.411', 'Colon enterocytes': '-0.220', 'Colon enteroendocrine cells': '0.275', 'Enteric glia cells': '0.283', 'Mitotic cells (Colon)': '-0.353', 'Mitotic cells (Heart)': '0.488', 'Podocytes': '-0.208', 'Ascending Loop of Henle cells': '0.472', 'Intercalated cells': '-0.101', 'Cholangiocyte': '0.328', 'NK-cells (Liver)': '-0.282', 'Respiratory ciliated cells': '0.031', 'Mitotic cells (Lung)': '-0.134', 'NK-cells (Lung)': '0.106', 'B-cells (Lung)': '-0.096', 'Alpha cells': '0.465', 'Beta cells': '0.248', 'Prostate glandular cells': '-0.066', 'Prostate basal glandular cells': '0.153', 'Urothelial cells': '0.148', 'Keratinocyte (other)': '0.370', 'Keratinocyte (granular)': '0.028', 'Hair cortex cells': '-0.097', 'Inner root sheath cells': '-0.116', 'Outer root sheath cells': '0.045', 'Sebaceous gland cells': '-0.130', 'Eccrine sweat gland cells': '-0.148', 'Adipocytes (Skin)': '-0.216', 'Mitotic cells (Skin)': '0.123', 'Parietal cells': '-0.675', 'Chief cells': '-0.560', 'Gastric mucous cells': '-0.394', 'Gastric enteroendocrine cells': '-0.419', 'Mitotic cells (Stomach)': '0.010', 'Parafollicular cells': '0.121', 'Thyroid glandular cells': '0.332', 'Mitotic cells (Thyroid)': '-0.111', 'Adrenal cortex cells': '0.411', 'Adrenal medulla cells': '0.054', 'Mitotic cells (Adrenal gland)': '0.126', 'Minor salivary glandular cells': '0.528', 'Minor salivary gland ductal cells': '0.051', 'Minor salivary gland basal cells': '0.343', 'Mitotic cells (Minor salivary gland)': '0.366', 'Adipocytes (Minor salivary gland)': '0.259', 'Somatotropes': '0.096', 'Lactotropes': '0.147', 'Gonadotropes': '0.177', 'Corticotropes': '0.081', 'Thyrotropes': '0.231', 'Undifferentiated cells (Pituitary gland)': '0.121', 'Mitotic cells (Spleen)': '-0.317', 'Platelets': '-0.211', 'Erythrocytes': '-0.166', 'Hematopoietic stem cells': '-0.327', 'B-cells (Spleen)': '0.317', 'NK-cells (Spleen)': '0.221', 'Amygdala excitatory': '14.0', 'Cerebellar inhibitory': '15.4', 'Cge interneuron': '18.4', 'Deep-layer corticothalamic and 6b': '13.8', 'Deep-layer intratelencephalic': '15.5', 'Deep-layer near-projecting': '19.1', 'Eccentric medium spiny neuron': '16.4', 'Hippocampal ca1-3': '14.3', 'Hippocampal ca4': '11.3', 'Hippocampal dentate gyrus': '9.4', 'Lamp5-lhx6 and chandelier': '17.1', 'Lower rhombic lip': '16.0', 'Mammillary body': '14.6', 'Medium spiny neuron': '13.3', 'Mge interneuron': '16.9', 'Midbrain-derived inhibitory': '20.5', 'Miscellaneous': '13.4', 'Splatter': '17.1', 'Thalamic excitatory': '18.6', 'Upper rhombic lip': '14.5', 'Upper-layer intratelencephalic': '12.6', 'Astrocyte': '16.0', 'Bergmann glia': '11.0', 'Central nervous system macrophage': '14.4', 'Choroid plexus epithelial cell': '12.5', 'Committed oligodendrocyte precursor': '22.9', 'Ependymal cell': '24.3', 'Oligodendrocyte': '20.2', 'Oligodendrocyte precursor cell': '17.1', 'Endothelial cell': '18.7', 'Pericyte': '23.1', 'Vascular associated smooth muscle cell': '19.7', 'Fibroblast': '21.0', 'Leukocyte': '16.6', 'Basophil': '3.4', 'Eosinophil': '1.4', 'Neutrophil': '3.2', 'Classical monocyte': '11.6', 'Non-classical monocyte': '10.3', 'Intermediate monocyte': '3.6', 'T-reg': '3.5', 'GdT-cell': '1.9', 'MAIT T-cell': '2.6', 'Memory CD4 T-cell': '1.0', 'Naive CD4 T-cell': '10.0', 'Memory CD8 T-cell': '1.3', 'Naive CD8 T-cell': '13.4', 'Memory B-cell': '2.8', 'Naive B-cell': '10.0', 'Plasmacytoid DC': '2.9', 'Myeloid DC': '2.6', 'NK-cell': '17.9', 'Total PBMC': '2.5', 'Vd2 gdTCR': '2.0', 'Memory CD4 T-cell TFH': '30.2', 'Memory CD4 T-cell Th2': '16.5', 'Memory CD4 T-cell Th17': '15.8', 'Memory CD4 T-cell Th1\\/Th17': '10.3', 'Non-Vd2 gdTCR': '3.3', 'Memory CD4 T-cell Th1': '18.9', 'Terminal effector memory CD4 T-cell': '1.6', 'Central memory CD8 T-cell': '2.3', 'Effector memory CD8 T-cell': '3.5', 'Terminal effector memory CD8 T-cell': '2.2', 'Switched memory B-cell': '2.1', 'Plasmablast': '1.4', 'Non-switched memory B-cell': '4.5', 'Exhausted memory B-cell': '3.8', 'Progenitor cell': '2.3', 'Naive CD4 T-cell activated': '18.5', 'Naive CD8 T-cell activated': '20.1', 'Memory T-reg': '27.7', 'Naive T-reg': '19.2'}
| null |
{'Adipose Tissue': 41.86691029900332, 'Adrenal Gland': 31.331926356589147, 'Bladder': 53.721428571428575, 'Blood': 23.70091065662002, 'Blood Vessel': 58.04035205992509, 'Brain': 44.95235919757759, 'Breast': 44.076732026143794, 'Cervix Uteri': 59.77263157894737, 'Colon': 44.465442875481386, 'Esophagus': 45.26255363321799, 'Fallopian Tube': 58.37444444444444, 'Heart': 19.754106852497095, 'Kidney': 24.456359550561796, 'Liver': 18.412, 'Lung': 44.281903114186846, 'Muscle': 35.605865504358654, 'Nerve': 62.95943457189014, 'Ovary': 60.442388888888885, 'Pancreas': 14.760878048780487, 'Pituitary': 56.74102473498233, 'Prostate': 53.009346938775515, 'Salivary Gland': 35.05555555555556, 'Skin': 48.42487562189055, 'Small Intestine': 36.7720320855615, 'Spleen': 40.983360995850624, 'Stomach': 31.28072701949861, 'Testis': 68.30512465373961, 'Thyroid': 55.05839203675344, 'Uterus': 71.34232394366198, 'Vagina': 49.59333333333333}
|
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|
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|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 46.696547
| 0.877317
| 277
|
O43791
|
Q9H9S0
|
nan, 31624231:30595538
|
degron_data, UbiNet, UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
NANOG
|
MSVDPACPQSLPCFEASDCKESSPMPVICGPEENYPSLQMSSAEMPHTETVSPLPSSMDLLIQDSPDSSTSPKGKQPTSAEKSVAKKEDKVPVKKQKTRTVFSSTQLCVLNDRFQRQKYLSLQQMQELSNILNLSYKQVKTWFQNQRMKSKRWQKNNWPKNSNGVTQKASAPTYPSLYSSYHQGCLVNPTGNLPMWSNQTWNNSTWSNQTQNIQSWSNHSWNTQTWCTQSWNNQAWNSPFYNCGEESLQSCMQFQPNSPASDLEAALEAAGEGLNVIQQTTRYFSTPQTMDLFLNYSMNMQPEDV
|
Homo sapiens
|
Nucleus
|
Not detected
|
{'Ciliated cells': '0.5', 'Basal respiratory cells': '0.5', 'Club cells': '0.4', 'Ionocytes': '0.4', 'Mucus glandular cells': '0.3', 'Serous glandular cells': '0.1', 'Gastric mucus-secreting cells': '7.7', 'Proximal enterocytes': '0.1', 'Paneth cells': '0.2', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.1', 'Exocrine glandular cells': '-0.115', 'Basal prostatic cells': '0.6', 'Prostatic glandular cells': '0.4', 'Breast glandular cells': '0.193', 'Breast myoepithelial cells': '0.244', 'Glandular and luminal cells': '0.1', 'Secretory cells': '0.4', 'Basal keratinocytes': '0.5', 'Suprabasal keratinocytes': '0.6', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.2', 'Alveolar cells type 1': '-0.120', 'Alveolar cells type 2': '-0.198', 'Salivary duct cells': '0.2', 'Ductal cells': '0.124', 'Hepatocytes': '0.165', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.023', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.108', 'Sertoli cells': '-0.244', 'Granulosa cells': '1.2', 'Enteroendocrine cells': '0.6', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.196', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.6', 'Bipolar cells': '1.3', 'Horizontal cells': '2.5', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.1', 'Microglial cells': '0.0', 'Muller glia cells': '0.4', 'Schwann cells': '0.088', 'Spermatogonia': '0.008', 'Spermatocytes': '0.168', 'Early spermatids': '0.220', 'Late spermatids': '0.249', 'Oocytes': '0.0', 'Cytotrophoblasts': '1.1', 'Syncytiotrophoblasts': '0.6', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '0.3', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.064', 'Skeletal myocytes': '-0.035', 'Smooth muscle cells': '0.3', 'Adipocytes': '0.2', 'Melanocytes': '0.155', 'Fibroblasts': '0.3', 'Peritubular cells': '-0.129', 'Endometrial stromal cells': '0.2', 'Ovarian stromal cells': '1.0', 'Undifferentiated cells': '0.4', 'T-cells': '0.1', 'B-cells': '0.0', 'Plasma cells': '0.1', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.1', 'Hofbauer cells': '0.1', 'Kupffer cells': '0.3', 'Dendritic cells': '1.8', 'Langerhans cells': '0.099', 'Erythroid cells': '0.195', 'Adipocytes (Subcutaneous)': '-0.133', 'Adipocytes (Visceral)': '-0.136', 'Breast glandular cells (progenitors)': '0.154', 'Adipocytes (Breast)': '-0.177', 'Colon enterocytes': '-0.126', 'Colon enteroendocrine cells': '-0.027', 'Enteric glia cells': '0.195', 'Mitotic cells (Colon)': '-0.035', 'Mitotic cells (Heart)': '0.060', 'Podocytes': '-0.057', 'Ascending Loop of Henle cells': '0.153', 'Intercalated cells': '0.012', 'Cholangiocyte': '-0.007', 'NK-cells (Liver)': '0.099', 'Respiratory ciliated cells': '0.088', 'Mitotic cells (Lung)': '-0.040', 'NK-cells (Lung)': '0.096', 'B-cells (Lung)': '0.097', 'Alpha cells': '0.122', 'Beta cells': '0.046', 'Prostate glandular cells': '0.022', 'Prostate basal glandular cells': '0.082', 'Urothelial cells': '0.113', 'Keratinocyte (other)': '-0.013', 'Keratinocyte (granular)': '-0.225', 'Hair cortex cells': '0.014', 'Inner root sheath cells': '0.073', 'Outer root sheath cells': '0.150', 'Sebaceous gland cells': '0.078', 'Eccrine sweat gland cells': '0.000', 'Adipocytes (Skin)': '-0.028', 'Mitotic cells (Skin)': '0.186', 'Parietal cells': '-0.141', 'Chief cells': '-0.228', 'Gastric mucous cells': '0.039', 'Gastric enteroendocrine cells': '-0.115', 'Mitotic cells (Stomach)': '0.074', 'Parafollicular cells': '0.006', 'Thyroid glandular cells': '0.032', 'Mitotic cells (Thyroid)': '0.025', 'Adrenal cortex cells': '0.271', 'Adrenal medulla cells': '-0.055', 'Mitotic cells (Adrenal gland)': '0.164', 'Minor salivary glandular cells': '0.052', 'Minor salivary gland ductal cells': '0.168', 'Minor salivary gland basal cells': '-0.016', 'Mitotic cells (Minor salivary gland)': '-0.040', 'Adipocytes (Minor salivary gland)': '-0.049', 'Somatotropes': '0.064', 'Lactotropes': '-0.017', 'Gonadotropes': '-0.041', 'Corticotropes': '0.048', 'Thyrotropes': '0.005', 'Undifferentiated cells (Pituitary gland)': '0.065', 'Mitotic cells (Spleen)': '-0.043', 'Platelets': '-0.144', 'Erythrocytes': '0.029', 'Hematopoietic stem cells': '-0.032', 'B-cells (Spleen)': '0.020', 'NK-cells (Spleen)': '0.113', 'Amygdala excitatory': '0.1', 'Cerebellar inhibitory': '0.0', 'Cge interneuron': '0.1', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.3', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.2', 'Lamp5-lhx6 and chandelier': '0.1', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.1', 'Medium spiny neuron': '0.5', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.1', 'Thalamic excitatory': '0.1', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '0.2', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.1', 'Choroid plexus epithelial cell': '0.1', 'Committed oligodendrocyte precursor': '0.1', 'Ependymal cell': '0.1', 'Oligodendrocyte': '0.1', 'Oligodendrocyte precursor cell': '0.1', 'Endothelial cell': '0.0', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.0', 'Leukocyte': '0.0', 'Basophil': '2.4', 'Eosinophil': '0.1', 'Neutrophil': '3.3', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.3', 'Intermediate monocyte': '1.5', 'T-reg': '1.4', 'GdT-cell': '0.1', 'MAIT T-cell': '1.6', 'Memory CD4 T-cell': '0.1', 'Naive CD4 T-cell': '0.2', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.1', 'Naive B-cell': '0.3', 'Plasmacytoid DC': '7.0', 'Myeloid DC': '2.5', 'NK-cell': '0.3', 'Total PBMC': '1.1', 'Vd2 gdTCR': '1.4', 'Memory CD4 T-cell Th1\\/Th17': '0.3', 'Memory CD4 T-cell Th17': '0.3', 'Memory CD4 T-cell Th2': '0.4', 'Non-Vd2 gdTCR': '1.3', 'Memory CD4 T-cell Th1': '0.3', 'Memory CD4 T-cell TFH': '0.3', 'Terminal effector memory CD4 T-cell': '1.1', 'Central memory CD8 T-cell': '1.2', 'Effector memory CD8 T-cell': '1.6', 'Terminal effector memory CD8 T-cell': '1.5', 'Non-switched memory B-cell': '1.9', 'Plasmablast': '0.8', 'Switched memory B-cell': '1.4', 'Exhausted memory B-cell': '1.5', 'Progenitor cell': '1.8', 'Memory T-reg': '0.3', 'Naive CD4 T-cell activated': '0.3', 'Naive CD8 T-cell activated': '0.2', 'Naive T-reg': '0.3'}
|
2KT0, 4RBO
|
{'Adipose Tissue': 0.0166250431893687, 'Adrenal Gland': 0.0448654069767441, 'Bladder': 0.0214670476190476, 'Blood': 0.0088615575888051, 'Blood Vessel': 0.017651070411985, 'Brain': 0.0131253690386071, 'Breast': 0.0207821111111111, 'Cervix Uteri': 0.03015, 'Colon': 0.014835516046213, 'Esophagus': 0.0148964657439446, 'Fallopian Tube': 0.0235196666666666, 'Heart': 0.0071344529616724, 'Kidney': 0.0149307415730337, 'Liver': 0.0116242876106194, 'Lung': 0.0204034671280276, 'Muscle': 0.0057981780821917, 'Nerve': 0.0523946300484652, 'Ovary': 0.0340257111111111, 'Pancreas': 0.0120108170731707, 'Pituitary': 0.0336744664310954, 'Prostate': 0.0302747102040816, 'Salivary Gland': 0.0166028209876543, 'Skin': 0.019791855721393, 'Small Intestine': 0.0138084598930481, 'Spleen': 0.0229287676348547, 'Stomach': 0.0142725376044568, 'Testis': 0.1805380055401662, 'Thyroid': 0.0273788453292496, 'Uterus': 0.0368786126760563, 'Vagina': 0.0232640576923076}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[57.7, 63.08, 64.52, 63.48, 69.01, 64.57, 55.04, 73.38, 58.44, 54.1, 62.37, 51.04, 46.65, 51.92, 53.49, 46.55, 64.24, 55.66, 54.79, 52.42, 49.78, 55.15, 48.14, 63.17, 54.03, 63.82, 56.79, 53.01, 50.27, 49.01, 53.5, 48.9, 53.69, 51.42, 47.03, 63.93, 45.31, 60.03, 48.27, 46.16, 55.19, 49.34, 52.56, 49.2, 56.86, 55.9, 39.95, 51.8, 44.54, 41.68, 54.26, 43.0, 48.78, 48.7, 52.53, 56.01, 48.04, 62.64, 44.91, 53.2, 47.2, 55.85, 42.33, 49.18, 47.17, 66.52, 44.12, 45.43, 48.99, 46.52, 45.66, 53.64, 47.05, 43.14, 55.45, 44.37, 50.29, 40.52, 45.39, 50.73, 48.64, 44.51, 48.45, 52.22, 43.9, 53.27, 45.24, 56.91, 53.01, 60.59, 65.78, 65.64, 67.33, 68.62, 73.87, 77.5, 79.35, 86.05, 88.71, 89.45, 95.03, 97.2, 98.03, 97.96, 97.95, 98.26, 98.3, 98.15, 98.22, 98.57, 98.21, 98.17, 98.13, 98.35, 97.63, 97.36, 97.7, 97.38, 98.31, 97.8, 97.9, 97.89, 98.07, 98.2, 98.11, 98.27, 98.31, 98.3, 98.17, 98.04, 97.69, 97.69, 97.85, 97.26, 97.69, 98.12, 97.7, 97.54, 98.18, 98.08, 97.88, 98.27, 98.56, 98.0, 97.99, 97.84, 97.91, 97.65, 95.96, 94.4, 94.51, 93.34, 90.38, 86.6, 85.16, 82.39, 76.41, 63.35, 65.87, 61.75, 55.3, 56.41, 51.42, 50.84, 51.31, 48.06, 52.7, 47.14, 47.48, 50.49, 45.02, 55.73, 46.39, 54.33, 56.76, 43.45, 53.48, 50.44, 45.11, 44.73, 42.81, 46.54, 43.19, 37.18, 41.69, 46.54, 46.39, 45.28, 44.3, 44.7, 47.35, 46.1, 44.88, 55.03, 42.33, 41.2, 38.93, 34.59, 39.09, 37.55, 35.06, 37.53, 35.13, 39.27, 44.61, 38.72, 34.24, 37.31, 40.8, 41.89, 38.44, 35.52, 35.41, 35.68, 34.29, 34.14, 35.7, 35.83, 43.21, 38.84, 41.68, 41.59, 42.84, 38.46, 45.37, 37.92, 39.34, 41.94, 38.09, 43.17, 35.01, 40.34, 39.68, 42.53, 41.6, 35.89, 40.53, 36.44, 41.8, 43.08, 36.72, 40.27, 33.47, 38.55, 38.74, 39.51, 40.5, 45.29, 40.5, 38.21, 39.64, 45.66, 41.21, 39.2, 35.98, 44.13, 35.72, 38.36, 44.87, 39.73, 50.8, 38.62, 47.37, 42.77, 49.42, 48.17, 47.79, 45.42, 52.06, 49.78, 42.37, 46.59, 47.49, 48.14, 46.61, 48.92, 47.52, 45.88, 42.33, 42.84, 44.29, 48.65, 43.92, 52.7, 43.27, 44.25, 52.74, 45.25, 45.1, 56.39, 45.84, 54.18, 50.16, 48.7, 52.11, 42.23, 55.97, 53.17, 51.97, 53.22, 52.38, 59.98, 51.99, 56.82, 56.46]
|
[1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.95, 0.96, 0.96, 1.0, 1.0, 0.95, 1.0, 0.97, 1.0, 0.99, 0.97, 0.91, 0.95, 0.93, 0.97, 0.95, 0.95, 0.9, 0.96, 0.95, 0.9, 0.97, 0.92, 0.89, 0.98, 1.0, 0.98, 0.91, 0.97, 0.79, 0.89, 0.93, 0.97, 0.98, 0.98, 0.97, 0.99, 0.97, 0.76, 0.91, 0.74, 0.88, 0.93, 0.91, 0.95, 0.95, 0.97, 0.96, 0.99, 0.91, 0.92, 0.92, 0.92, 0.84, 0.83, 0.87, 0.89, 0.95, 0.97, 0.95, 0.96, 0.99, 1.0, 1.0, 0.95, 0.98, 0.9, 0.91, 0.92, 0.88, 0.95, 0.85, 0.99, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.92, 1.0, 0.78, 0.93, 0.87, 0.84, 0.8, 0.78, 0.87, 0.89, 0.91, 0.96, 0.86, 0.94, 0.82, 0.94, 0.3, 0.5, 0.71, 0.6, 0.19, 0.35, 0.64, 0.21, 0.0, 0.43, 0.37, 0.23, 0.08, 0.78, 0.72, 0.33, 0.35, 0.73, 0.11, 0.49, 0.57, 0.74, 0.19, 0.11, 0.47, 0.52, 0.03, 0.07, 0.74, 0.51, 0.11, 0.83, 0.15, 0.48, 0.35, 0.76, 0.33, 0.0, 0.52, 0.45, 0.1, 0.01, 0.44, 0.58, 0.13, 0.29, 0.35, 0.59, 0.37, 0.59, 0.66, 0.69, 0.63, 0.77, 0.81, 0.57, 0.69, 0.84, 0.86, 0.72, 0.78, 0.78, 0.75, 0.97, 0.98, 1.0, 1.0, 1.0, 0.95, 0.94, 0.79, 0.94, 0.89, 0.85, 0.82, 0.86, 0.86, 0.65, 0.87, 0.85, 0.96, 1.0, 0.97, 1.0, 1.0, 1.0, 0.97, 1.0, 0.96, 0.85, 0.99, 0.81, 0.89, 0.77, 0.63, 0.47, 0.87, 0.91, 0.67, 0.73, 0.7, 0.66, 0.85, 0.93, 0.84, 0.91, 0.96, 0.85, 0.84, 0.87, 0.59, 0.83, 0.69, 0.62, 0.78, 0.56, 0.97, 0.56, 0.91, 0.79, 0.73, 0.85, 0.83, 0.95, 0.87, 0.69, 0.94, 0.79, 0.87, 0.97, 0.73, 0.94, 0.85, 0.77, 1.0, 0.81, 0.77, 0.92, 0.88, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 1.0, 0.92, 1.0, 0.97, 0.89, 0.99, 0.9, 0.98, 1.0, 1.0, 1.0, 0.97, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 0.98, 0.92, 0.87, 0.9, 0.87, 0.92, 1.0, 0.9, 0.99, 0.99, 0.88, 1.0, 0.84, 1.0, 0.93, 1.0, 1.0, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 57.64459
| 0.824557
| 2,367
|
O43791
|
Q9HCU9
|
22199232, UNIPROT
|
UbiNet, UbiBrowser, 31181401
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
BRMS1
|
MPVQPPSKDTEEMEAEGDSAAEMNGEEEESEEERSGSQTESEEESSEMDDEDYERRRSECVSEMLDLEKQFSELKEKLFRERLSQLRLRLEEVGAERAPEYTEPLGGLQRSLKIRIQVAGIYKGFCLDVIRNKYECELQGAKQHLESEKLLLYDTLQGELQERIQRLEEDRQSLDLSSEWWDDKLHARGSSRSWDSLPPSKRKKAPLVSGPYIVYMLQEIDILEDWTAIKKARAAVSPQKRKSDGP
|
Homo sapiens
|
Nucleus, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '25.9', 'Basal respiratory cells': '42.7', 'Club cells': '27.9', 'Ionocytes': '31.7', 'Mucus glandular cells': '22.9', 'Serous glandular cells': '29.1', 'Gastric mucus-secreting cells': '31.2', 'Proximal enterocytes': '76.7', 'Paneth cells': '63.1', 'Distal enterocytes': '100.8', 'Intestinal goblet cells': '43.5', 'Exocrine glandular cells': '-0.755', 'Basal prostatic cells': '24.0', 'Prostatic glandular cells': '40.8', 'Breast glandular cells': '0.515', 'Breast myoepithelial cells': '0.151', 'Glandular and luminal cells': '19.4', 'Secretory cells': '36.8', 'Basal keratinocytes': '51.1', 'Suprabasal keratinocytes': '49.2', 'Basal squamous epithelial cells': '29.5', 'Squamous epithelial cells': '31.5', 'Alveolar cells type 1': '-0.088', 'Alveolar cells type 2': '0.142', 'Salivary duct cells': '19.3', 'Ductal cells': '0.492', 'Hepatocytes': '0.351', 'Cholangiocytes': '36.2', 'Proximal tubular cells': '0.167', 'Distal tubular cells': '36.9', 'Collecting duct cells': '33.1', 'Mesothelial cells': '0.189', 'Sertoli cells': '-0.235', 'Granulosa cells': '17.7', 'Enteroendocrine cells': '37.1', 'Pancreatic endocrine cells': '59.4', 'Leydig cells': '-0.311', 'Excitatory neurons': '2.8', 'Inhibitory neurons': '2.1', 'Cone photoreceptor cells': '20.4', 'Rod photoreceptor cells': '11.0', 'Bipolar cells': '10.1', 'Horizontal cells': '12.0', 'Astrocytes': '4.0', 'Oligodendrocyte precursor cells': '2.8', 'Oligodendrocytes': '4.8', 'Microglial cells': '5.4', 'Muller glia cells': '29.0', 'Schwann cells': '-0.028', 'Spermatogonia': '-0.051', 'Spermatocytes': '0.139', 'Early spermatids': '0.558', 'Late spermatids': '0.322', 'Oocytes': '100.7', 'Cytotrophoblasts': '64.4', 'Syncytiotrophoblasts': '68.5', 'Extravillous trophoblasts': '72.6', 'Endothelial cells': '30.2', 'Lymphatic endothelial cells': '30.7', 'Cardiomyocytes': '0.452', 'Skeletal myocytes': '-0.356', 'Smooth muscle cells': '23.4', 'Adipocytes': '27.1', 'Melanocytes': '0.217', 'Fibroblasts': '23.7', 'Peritubular cells': '-0.209', 'Endometrial stromal cells': '16.8', 'Ovarian stromal cells': '22.0', 'Undifferentiated cells': '42.7', 'T-cells': '41.2', 'B-cells': '36.2', 'Plasma cells': '35.4', 'Nk-cells': '41.3', 'Granulocytes': '24.0', 'Monocytes': '34.0', 'Macrophages': '39.4', 'Hofbauer cells': '69.7', 'Kupffer cells': '39.8', 'Dendritic cells': '30.6', 'Langerhans cells': '0.226', 'Erythroid cells': '-0.127', 'Adipocytes (Subcutaneous)': '0.084', 'Adipocytes (Visceral)': '-0.035', 'Breast glandular cells (progenitors)': '0.283', 'Adipocytes (Breast)': '-0.256', 'Colon enterocytes': '0.011', 'Colon enteroendocrine cells': '0.071', 'Enteric glia cells': '0.052', 'Mitotic cells (Colon)': '0.064', 'Mitotic cells (Heart)': '0.476', 'Podocytes': '-0.082', 'Ascending Loop of Henle cells': '0.451', 'Intercalated cells': '0.037', 'Cholangiocyte': '0.355', 'NK-cells (Liver)': '-0.374', 'Respiratory ciliated cells': '-0.051', 'Mitotic cells (Lung)': '0.108', 'NK-cells (Lung)': '-0.266', 'B-cells (Lung)': '-0.290', 'Alpha cells': '0.324', 'Beta cells': '0.172', 'Prostate glandular cells': '0.516', 'Prostate basal glandular cells': '0.580', 'Urothelial cells': '0.172', 'Keratinocyte (other)': '0.332', 'Keratinocyte (granular)': '0.138', 'Hair cortex cells': '-0.003', 'Inner root sheath cells': '-0.012', 'Outer root sheath cells': '-0.059', 'Sebaceous gland cells': '0.025', 'Eccrine sweat gland cells': '-0.412', 'Adipocytes (Skin)': '-0.318', 'Mitotic cells (Skin)': '0.005', 'Parietal cells': '-0.105', 'Chief cells': '0.111', 'Gastric mucous cells': '0.219', 'Gastric enteroendocrine cells': '0.122', 'Mitotic cells (Stomach)': '0.352', 'Parafollicular cells': '0.086', 'Thyroid glandular cells': '0.212', 'Mitotic cells (Thyroid)': '-0.098', 'Adrenal cortex cells': '0.320', 'Adrenal medulla cells': '0.009', 'Mitotic cells (Adrenal gland)': '0.109', 'Minor salivary glandular cells': '0.574', 'Minor salivary gland ductal cells': '-0.063', 'Minor salivary gland basal cells': '0.417', 'Mitotic cells (Minor salivary gland)': '0.430', 'Adipocytes (Minor salivary gland)': '0.128', 'Somatotropes': '-0.038', 'Lactotropes': '-0.177', 'Gonadotropes': '-0.073', 'Corticotropes': '0.012', 'Thyrotropes': '-0.032', 'Undifferentiated cells (Pituitary gland)': '0.151', 'Mitotic cells (Spleen)': '-0.302', 'Platelets': '-0.074', 'Erythrocytes': '-0.108', 'Hematopoietic stem cells': '-0.165', 'B-cells (Spleen)': '0.370', 'NK-cells (Spleen)': '0.190', 'Amygdala excitatory': '4.7', 'Cerebellar inhibitory': '4.1', 'Cge interneuron': '2.8', 'Deep-layer corticothalamic and 6b': '3.5', 'Deep-layer intratelencephalic': '4.1', 'Deep-layer near-projecting': '3.3', 'Eccentric medium spiny neuron': '5.0', 'Hippocampal ca1-3': '5.4', 'Hippocampal ca4': '4.8', 'Hippocampal dentate gyrus': '5.2', 'Lamp5-lhx6 and chandelier': '2.5', 'Lower rhombic lip': '3.7', 'Mammillary body': '3.1', 'Medium spiny neuron': '5.8', 'Mge interneuron': '3.0', 'Midbrain-derived inhibitory': '2.7', 'Miscellaneous': '4.3', 'Splatter': '3.0', 'Thalamic excitatory': '3.4', 'Upper rhombic lip': '4.2', 'Upper-layer intratelencephalic': '4.6', 'Astrocyte': '6.9', 'Bergmann glia': '6.6', 'Central nervous system macrophage': '8.2', 'Choroid plexus epithelial cell': '6.7', 'Committed oligodendrocyte precursor': '9.0', 'Ependymal cell': '7.5', 'Oligodendrocyte': '9.4', 'Oligodendrocyte precursor cell': '4.8', 'Endothelial cell': '9.8', 'Pericyte': '7.4', 'Vascular associated smooth muscle cell': '9.6', 'Fibroblast': '4.8', 'Leukocyte': '10.5', 'Basophil': '105.1', 'Eosinophil': '81.0', 'Neutrophil': '170.2', 'Classical monocyte': '47.2', 'Non-classical monocyte': '39.0', 'Intermediate monocyte': '99.9', 'T-reg': '86.6', 'GdT-cell': '61.3', 'MAIT T-cell': '101.0', 'Memory CD4 T-cell': '65.3', 'Naive CD4 T-cell': '34.5', 'Memory CD8 T-cell': '58.6', 'Naive CD8 T-cell': '42.9', 'Memory B-cell': '79.5', 'Naive B-cell': '29.2', 'Plasmacytoid DC': '105.8', 'Myeloid DC': '91.4', 'NK-cell': '55.7', 'Total PBMC': '107.1', 'Vd2 gdTCR': '108.6', 'Memory CD4 T-cell Th1\\/Th17': '44.9', 'Memory CD4 T-cell Th17': '60.8', 'Memory CD4 T-cell Th2': '58.7', 'Non-Vd2 gdTCR': '103.5', 'Memory CD4 T-cell Th1': '63.6', 'Memory CD4 T-cell TFH': '79.5', 'Terminal effector memory CD4 T-cell': '86.2', 'Central memory CD8 T-cell': '80.7', 'Effector memory CD8 T-cell': '101.4', 'Terminal effector memory CD8 T-cell': '93.0', 'Non-switched memory B-cell': '96.2', 'Plasmablast': '112.0', 'Switched memory B-cell': '96.9', 'Exhausted memory B-cell': '88.6', 'Progenitor cell': '56.3', 'Memory T-reg': '94.6', 'Naive CD4 T-cell activated': '40.3', 'Naive CD8 T-cell activated': '56.1', 'Naive T-reg': '47.0'}
|
2XUS, 4AUV
|
{'Adipose Tissue': 42.621602990033225, 'Adrenal Gland': 35.55468992248062, 'Bladder': 44.95190476190477, 'Blood': 52.75018729817008, 'Blood Vessel': 40.02770786516854, 'Brain': 19.80136373959122, 'Breast': 45.95662309368192, 'Cervix Uteri': 46.020526315789475, 'Colon': 38.78522464698331, 'Esophagus': 40.815121107266435, 'Fallopian Tube': 43.68555555555556, 'Heart': 16.040677119628338, 'Kidney': 34.09786516853933, 'Liver': 18.940079646017697, 'Lung': 49.00885813148789, 'Muscle': 27.34676587795766, 'Nerve': 46.24487883683361, 'Ovary': 40.01455555555555, 'Pancreas': 25.357009146341465, 'Pituitary': 33.78441696113074, 'Prostate': 63.20008163265306, 'Salivary Gland': 44.16759259259259, 'Skin': 62.315428413488114, 'Small Intestine': 46.61160427807487, 'Spleen': 63.959211618257264, 'Stomach': 37.81621169916435, 'Testis': 67.95346260387812, 'Thyroid': 56.41784073506891, 'Uterus': 46.91302816901408, 'Vagina': 46.939166666666665}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[43.22, 50.17, 59.62, 52.23, 70.46, 59.75, 41.27, 59.55, 41.43, 47.16, 49.32, 43.36, 52.2, 46.84, 51.08, 48.59, 40.33, 44.6, 43.62, 45.77, 37.66, 49.49, 47.07, 44.56, 40.74, 38.66, 48.53, 44.9, 39.89, 46.45, 40.77, 47.76, 44.23, 48.05, 52.55, 45.44, 49.55, 45.27, 51.77, 44.07, 46.44, 45.45, 40.3, 47.49, 47.14, 52.65, 54.09, 62.74, 75.09, 85.31, 87.07, 90.99, 89.81, 93.71, 94.83, 94.32, 96.21, 96.45, 97.04, 97.29, 97.77, 97.79, 97.87, 98.21, 98.04, 98.3, 98.41, 98.35, 98.45, 98.48, 98.46, 98.37, 98.46, 98.59, 98.58, 98.54, 98.53, 98.61, 98.6, 98.65, 98.63, 98.66, 98.64, 98.6, 98.41, 98.33, 98.34, 97.95, 97.4, 97.82, 98.11, 97.93, 97.42, 97.13, 97.68, 96.13, 96.62, 97.35, 96.63, 95.97, 96.99, 97.77, 97.99, 98.34, 97.8, 98.07, 98.39, 98.54, 98.48, 98.58, 98.6, 98.62, 98.78, 98.73, 98.78, 98.72, 98.73, 98.82, 98.7, 98.7, 98.78, 98.82, 98.8, 98.77, 98.73, 98.71, 98.79, 98.79, 98.69, 98.72, 98.8, 98.65, 98.69, 98.69, 98.77, 98.44, 98.59, 98.56, 98.68, 98.6, 98.67, 98.61, 98.65, 98.44, 98.41, 98.47, 98.38, 98.52, 98.51, 98.44, 98.26, 98.29, 98.3, 98.37, 98.39, 98.28, 98.32, 98.35, 98.31, 98.19, 98.13, 97.91, 98.05, 97.23, 97.6, 97.41, 96.47, 96.03, 94.87, 94.48, 93.19, 90.33, 88.73, 82.75, 78.5, 75.41, 73.46, 68.68, 60.82, 59.25, 62.1, 59.41, 57.61, 57.94, 54.2, 53.85, 51.22, 43.89, 49.14, 46.02, 46.25, 51.79, 45.32, 44.79, 37.74, 46.91, 54.69, 58.73, 57.18, 51.6, 50.82, 57.3, 57.06, 59.46, 62.03, 64.39, 61.93, 66.36, 55.59, 71.36, 72.62, 68.49, 71.4, 69.48, 72.66, 79.32, 78.93, 86.03, 87.11, 89.42, 90.55, 89.26, 92.04, 91.87, 91.81, 90.07, 93.21, 91.63, 90.01, 90.74, 89.85, 87.63, 85.75, 81.04, 77.91, 71.31, 60.79, 59.53, 55.39, 53.73, 54.27, 51.96, 57.3, 57.59, 65.92, 57.51]
|
[1.0, 1.0, 0.96, 0.98, 0.91, 0.91, 0.93, 0.87, 0.97, 0.84, 1.0, 1.0, 0.98, 1.0, 1.0, 0.99, 0.93, 0.97, 0.88, 0.89, 0.79, 0.98, 0.95, 1.0, 0.93, 0.96, 0.96, 0.96, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.91, 0.86, 0.84, 0.87, 0.88, 0.99, 0.98, 0.91, 0.9, 0.76, 0.9, 0.35, 0.52, 0.7, 0.68, 0.3, 0.53, 0.52, 0.52, 0.63, 0.62, 0.56, 0.55, 0.55, 0.5, 0.48, 0.64, 0.57, 0.62, 0.49, 0.38, 0.61, 0.61, 0.6, 0.58, 0.43, 0.54, 0.62, 0.62, 0.57, 0.64, 0.66, 0.64, 0.6, 0.54, 0.49, 0.46, 0.55, 0.42, 0.45, 0.62, 0.55, 0.54, 0.68, 0.67, 0.34, 0.47, 0.73, 0.52, 0.79, 0.77, 0.08, 0.48, 0.79, 0.69, 0.37, 0.75, 0.52, 0.52, 0.25, 0.3, 0.66, 0.57, 0.66, 0.42, 0.59, 0.64, 0.58, 0.72, 0.63, 0.55, 0.55, 0.51, 0.54, 0.57, 0.66, 0.65, 0.33, 0.6, 0.36, 0.57, 0.49, 0.5, 0.63, 0.64, 0.53, 0.6, 0.66, 0.44, 0.61, 0.7, 0.44, 0.56, 0.4, 0.55, 0.56, 0.55, 0.58, 0.71, 0.61, 0.57, 0.49, 0.6, 0.61, 0.56, 0.67, 0.59, 0.63, 0.45, 0.51, 0.53, 0.3, 0.57, 0.56, 0.55, 0.55, 0.53, 0.52, 0.52, 0.43, 0.49, 0.52, 0.48, 0.49, 0.63, 0.57, 0.5, 0.71, 0.44, 0.48, 0.31, 0.5, 0.62, 0.7, 0.64, 0.54, 0.61, 0.68, 0.79, 0.85, 0.55, 0.96, 0.87, 0.98, 1.0, 0.98, 1.0, 0.95, 0.98, 0.87, 0.96, 0.98, 0.96, 0.89, 0.99, 0.91, 0.98, 0.88, 0.85, 0.91, 0.85, 0.84, 0.92, 0.53, 0.95, 0.81, 0.68, 0.64, 0.65, 0.89, 0.42, 0.64, 0.76, 0.66, 0.35, 0.54, 0.62, 0.63, 0.51, 0.57, 0.57, 0.51, 0.54, 0.56, 0.77, 0.49, 0.77, 0.64, 0.79, 0.77, 0.67, 0.86, 0.87, 0.92, 0.92, 0.94, 0.93, 0.96, 0.96, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 78.673496
| 0.686382
| 2,570
|
O43791
|
Q9NZQ7
|
29160310
|
UbiBrowser
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
CD274
|
MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTHLVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET
|
Homo sapiens
|
Cell membrane, Early endosome membrane, Recycling endosome membrane, Nucleus, Cell membrane, Endomembrane system, Secreted
|
Tissue enhanced (lung)
|
{'Ciliated cells': '1.7', 'Basal respiratory cells': '4.1', 'Club cells': '1.7', 'Ionocytes': '1.8', 'Mucus glandular cells': '0.4', 'Serous glandular cells': '1.0', 'Gastric mucus-secreting cells': '0.6', 'Proximal enterocytes': '1.6', 'Paneth cells': '0.1', 'Distal enterocytes': '0.7', 'Intestinal goblet cells': '1.2', 'Exocrine glandular cells': '-0.460', 'Basal prostatic cells': '2.5', 'Prostatic glandular cells': '1.5', 'Breast glandular cells': '0.292', 'Breast myoepithelial cells': '0.355', 'Glandular and luminal cells': '0.7', 'Secretory cells': '1.4', 'Basal keratinocytes': '3.8', 'Suprabasal keratinocytes': '3.6', 'Basal squamous epithelial cells': '1.3', 'Squamous epithelial cells': '1.1', 'Alveolar cells type 1': '0.153', 'Alveolar cells type 2': '-0.224', 'Salivary duct cells': '1.5', 'Ductal cells': '0.440', 'Hepatocytes': '0.114', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.070', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.124', 'Sertoli cells': '-0.156', 'Granulosa cells': '0.5', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '0.045', 'Excitatory neurons': '1.8', 'Inhibitory neurons': '3.2', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '0.1', 'Bipolar cells': '1.2', 'Horizontal cells': '0.0', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '0.8', 'Microglial cells': '8.1', 'Muller glia cells': '0.7', 'Schwann cells': '0.370', 'Spermatogonia': '0.087', 'Spermatocytes': '-0.033', 'Early spermatids': '0.239', 'Late spermatids': '-0.118', 'Oocytes': '0.0', 'Cytotrophoblasts': '6.1', 'Syncytiotrophoblasts': '54.7', 'Extravillous trophoblasts': '31.3', 'Endothelial cells': '8.1', 'Lymphatic endothelial cells': '7.3', 'Cardiomyocytes': '0.601', 'Skeletal myocytes': '0.551', 'Smooth muscle cells': '1.1', 'Adipocytes': '3.3', 'Melanocytes': '-0.130', 'Fibroblasts': '2.2', 'Peritubular cells': '0.195', 'Endometrial stromal cells': '0.2', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '0.5', 'T-cells': '3.1', 'B-cells': '1.9', 'Plasma cells': '3.0', 'Nk-cells': '1.5', 'Granulocytes': '43.8', 'Monocytes': '2.4', 'Macrophages': '7.8', 'Hofbauer cells': '4.8', 'Kupffer cells': '1.9', 'Dendritic cells': '0.0', 'Langerhans cells': '0.034', 'Erythroid cells': '0.014', 'Adipocytes (Subcutaneous)': '-0.317', 'Adipocytes (Visceral)': '-0.324', 'Breast glandular cells (progenitors)': '0.033', 'Adipocytes (Breast)': '-0.423', 'Colon enterocytes': '-0.017', 'Colon enteroendocrine cells': '0.354', 'Enteric glia cells': '0.483', 'Mitotic cells (Colon)': '0.018', 'Mitotic cells (Heart)': '0.454', 'Podocytes': '0.161', 'Ascending Loop of Henle cells': '0.156', 'Intercalated cells': '0.026', 'Cholangiocyte': '0.298', 'NK-cells (Liver)': '-0.052', 'Respiratory ciliated cells': '0.018', 'Mitotic cells (Lung)': '-0.158', 'NK-cells (Lung)': '0.379', 'B-cells (Lung)': '0.130', 'Alpha cells': '0.298', 'Beta cells': '0.083', 'Prostate glandular cells': '-0.402', 'Prostate basal glandular cells': '0.036', 'Urothelial cells': '0.341', 'Keratinocyte (other)': '-0.308', 'Keratinocyte (granular)': '-0.404', 'Hair cortex cells': '0.158', 'Inner root sheath cells': '0.181', 'Outer root sheath cells': '0.291', 'Sebaceous gland cells': '0.017', 'Eccrine sweat gland cells': '0.311', 'Adipocytes (Skin)': '0.149', 'Mitotic cells (Skin)': '0.087', 'Parietal cells': '-0.475', 'Chief cells': '-0.260', 'Gastric mucous cells': '-0.198', 'Gastric enteroendocrine cells': '-0.128', 'Mitotic cells (Stomach)': '0.007', 'Parafollicular cells': '0.041', 'Thyroid glandular cells': '0.081', 'Mitotic cells (Thyroid)': '0.156', 'Adrenal cortex cells': '0.049', 'Adrenal medulla cells': '0.306', 'Mitotic cells (Adrenal gland)': '-0.033', 'Minor salivary glandular cells': '0.255', 'Minor salivary gland ductal cells': '0.133', 'Minor salivary gland basal cells': '0.267', 'Mitotic cells (Minor salivary gland)': '0.313', 'Adipocytes (Minor salivary gland)': '0.273', 'Somatotropes': '-0.077', 'Lactotropes': '0.105', 'Gonadotropes': '-0.021', 'Corticotropes': '0.092', 'Thyrotropes': '0.269', 'Undifferentiated cells (Pituitary gland)': '0.109', 'Mitotic cells (Spleen)': '-0.143', 'Platelets': '-0.187', 'Erythrocytes': '-0.070', 'Hematopoietic stem cells': '-0.313', 'B-cells (Spleen)': '0.101', 'NK-cells (Spleen)': '0.251', 'Amygdala excitatory': '1.4', 'Cerebellar inhibitory': '1.4', 'Cge interneuron': '1.9', 'Deep-layer corticothalamic and 6b': '1.1', 'Deep-layer intratelencephalic': '1.0', 'Deep-layer near-projecting': '1.5', 'Eccentric medium spiny neuron': '2.3', 'Hippocampal ca1-3': '2.7', 'Hippocampal ca4': '1.1', 'Hippocampal dentate gyrus': '2.0', 'Lamp5-lhx6 and chandelier': '2.1', 'Lower rhombic lip': '3.4', 'Mammillary body': '6.4', 'Medium spiny neuron': '2.3', 'Mge interneuron': '5.4', 'Midbrain-derived inhibitory': '1.4', 'Miscellaneous': '1.1', 'Splatter': '4.5', 'Thalamic excitatory': '3.8', 'Upper rhombic lip': '3.3', 'Upper-layer intratelencephalic': '1.1', 'Astrocyte': '1.9', 'Bergmann glia': '3.3', 'Central nervous system macrophage': '36.7', 'Choroid plexus epithelial cell': '2.2', 'Committed oligodendrocyte precursor': '0.7', 'Ependymal cell': '2.1', 'Oligodendrocyte': '0.4', 'Oligodendrocyte precursor cell': '4.3', 'Endothelial cell': '5.4', 'Pericyte': '4.0', 'Vascular associated smooth muscle cell': '4.0', 'Fibroblast': '4.2', 'Leukocyte': '4.7', 'Basophil': '41.7', 'Eosinophil': '0.2', 'Neutrophil': '132.2', 'Classical monocyte': '0.5', 'Non-classical monocyte': '0.7', 'Intermediate monocyte': '3.3', 'T-reg': '8.8', 'GdT-cell': '0.7', 'MAIT T-cell': '10.1', 'Memory CD4 T-cell': '1.4', 'Naive CD4 T-cell': '8.3', 'Memory CD8 T-cell': '1.1', 'Naive CD8 T-cell': '4.9', 'Memory B-cell': '0.5', 'Naive B-cell': '0.9', 'Plasmacytoid DC': '0.7', 'Myeloid DC': '0.4', 'NK-cell': '9.0', 'Total PBMC': '5.2', 'Vd2 gdTCR': '11.6', 'Memory CD4 T-cell Th1\\/Th17': '16.2', 'Memory CD4 T-cell Th17': '17.3', 'Memory CD4 T-cell Th2': '13.3', 'Non-Vd2 gdTCR': '11.2', 'Memory CD4 T-cell Th1': '15.1', 'Memory CD4 T-cell TFH': '18.3', 'Terminal effector memory CD4 T-cell': '10.2', 'Central memory CD8 T-cell': '8.4', 'Effector memory CD8 T-cell': '9.4', 'Terminal effector memory CD8 T-cell': '11.9', 'Non-switched memory B-cell': '4.4', 'Plasmablast': '3.8', 'Switched memory B-cell': '5.7', 'Exhausted memory B-cell': '2.3', 'Progenitor cell': '1.2', 'Memory T-reg': '8.6', 'Naive CD4 T-cell activated': '248.5', 'Naive CD8 T-cell activated': '135.6', 'Naive T-reg': '5.9'}
|
3BIK, 3BIS, 3FN3, 3SBW, 4Z18, 4ZQK, 5C3T, 5GGT, 5GRJ, 5IUS, 5J89, 5J8O, 5JDR, 5JDS, 5N2D, 5N2F, 5NIU, 5O45, 5O4Y, 5X8L, 5X8M, 5XJ4, 5XXY, 6L8R, 6NM7, 6NM8, 6NNV, 6NOJ, 6NOS, 6NP9, 6PV9, 6R3K, 6RPG, 6VQN, 6YCR, 7BEA, 7C88, 7CZD, 7DCV, 7DY7, 7NLD, 7OUN, 7SJQ, 7TPS, 7UX5, 7UXO, 7UXP, 7UXQ, 7VUN, 7XAD, 7XAE, 7XYQ, 7YDS, 8ALX, 8AOK, 8AOM, 8JBA, 8K5N, 8OR1, 8P1O, 8R6Q, 8RPB
|
{'Adipose Tissue': 4.010519019933555, 'Adrenal Gland': 1.4790174418604651, 'Bladder': 2.053585714285714, 'Blood': 18.100414284176537, 'Blood Vessel': 3.658951310861423, 'Brain': 1.4785319190007569, 'Breast': 2.7507725490196075, 'Cervix Uteri': 3.717368421052631, 'Colon': 1.8126192554557128, 'Esophagus': 2.5542509342560553, 'Fallopian Tube': 3.236555555555556, 'Heart': 5.293013008130082, 'Kidney': 2.5292977528089886, 'Liver': 1.9062814159292032, 'Lung': 33.764228373702416, 'Muscle': 1.508057907845579, 'Nerve': 2.847840064620355, 'Ovary': 2.411197222222222, 'Pancreas': 1.309070426829268, 'Pituitary': 5.106909187279152, 'Prostate': 3.5440738775510203, 'Salivary Gland': 1.9220586419753083, 'Skin': 1.683699347705915, 'Small Intestine': 3.359980748663102, 'Spleen': 17.006128630705394, 'Stomach': 1.9103685236768804, 'Testis': 1.625530193905817, 'Thyroid': 5.0816431852986215, 'Uterus': 4.01242323943662, 'Vagina': 2.897435897435898}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
[62.98, 69.72, 72.81, 69.94, 74.89, 77.03, 75.01, 76.31, 75.83, 73.14, 71.5, 71.01, 67.25, 65.82, 62.65, 62.7, 68.99, 81.29, 91.78, 95.17, 97.39, 97.67, 97.95, 97.3, 96.46, 95.26, 98.21, 98.1, 96.8, 97.43, 96.62, 96.43, 95.29, 97.39, 98.18, 98.11, 98.41, 98.33, 98.54, 98.33, 98.2, 97.23, 95.67, 94.59, 86.68, 86.14, 92.42, 95.03, 95.29, 95.1, 94.94, 95.27, 97.31, 97.61, 98.24, 98.0, 98.4, 97.46, 97.59, 90.81, 90.55, 96.56, 96.97, 98.11, 97.83, 97.26, 97.45, 96.4, 93.78, 92.16, 93.62, 92.61, 91.01, 91.68, 92.36, 93.98, 96.41, 97.51, 96.51, 95.31, 96.87, 95.34, 94.79, 97.06, 97.82, 96.7, 97.49, 97.16, 95.28, 94.91, 96.88, 97.16, 94.09, 95.84, 97.35, 98.17, 98.26, 98.4, 98.39, 98.43, 98.55, 98.33, 96.72, 97.64, 95.38, 94.99, 94.43, 97.0, 97.04, 97.74, 98.17, 98.43, 98.15, 98.04, 98.12, 98.15, 97.44, 96.1, 91.13, 93.29, 95.79, 97.85, 97.47, 98.01, 98.11, 98.47, 98.49, 98.46, 97.37, 96.91, 95.45, 96.39, 96.53, 97.5, 96.31, 96.66, 98.38, 98.12, 97.93, 97.73, 97.41, 95.85, 95.11, 94.86, 92.7, 89.86, 90.58, 93.17, 93.52, 96.02, 96.34, 97.71, 98.17, 98.6, 98.61, 98.32, 98.17, 97.52, 96.91, 95.73, 95.59, 95.77, 97.37, 96.9, 98.18, 98.09, 98.48, 98.18, 96.59, 95.05, 94.22, 91.94, 95.87, 97.06, 97.45, 95.37, 96.34, 97.82, 98.22, 97.84, 97.54, 96.92, 95.17, 93.9, 88.25, 83.57, 85.0, 82.73, 89.86, 95.98, 97.18, 97.75, 98.14, 98.37, 98.62, 98.44, 98.35, 97.12, 97.03, 96.02, 94.58, 91.95, 92.1, 93.34, 95.47, 97.41, 98.16, 98.41, 98.34, 98.27, 98.37, 97.71, 95.18, 92.15, 86.03, 87.87, 93.19, 95.37, 97.19, 98.06, 98.19, 98.21, 98.1, 97.91, 97.36, 96.2, 92.56, 86.49, 77.41, 72.3, 60.62, 54.6, 48.76, 50.75, 56.2, 58.48, 56.95, 60.7, 65.22, 67.86, 76.6, 79.79, 81.93, 88.03, 89.26, 90.55, 92.78, 93.51, 93.3, 92.78, 93.95, 92.07, 91.81, 90.32, 92.22, 87.92, 88.54, 88.25, 85.43, 85.34, 80.63, 76.29, 72.26, 62.42, 59.76, 56.92, 55.02, 53.01, 55.72, 49.78, 53.27, 53.55, 51.27, 55.88, 52.15, 54.3, 54.54, 51.03, 53.8, 52.27, 51.68, 52.47, 51.78, 51.07, 53.78, 52.94, 45.52, 47.11, 48.53, 46.02]
|
[0.85, 0.86, 0.7, 0.7, 0.51, 0.55, 0.62, 0.62, 0.57, 0.5, 0.51, 0.6, 0.53, 0.67, 0.7, 0.6, 0.67, 0.47, 0.16, 0.52, 0.0, 0.53, 0.31, 0.48, 0.52, 0.63, 0.5, 0.11, 0.67, 0.12, 0.44, 0.2, 0.49, 0.34, 0.66, 0.03, 0.39, 0.0, 0.3, 0.0, 0.44, 0.07, 0.48, 0.26, 0.98, 0.93, 0.91, 0.23, 0.51, 0.38, 0.59, 0.42, 0.0, 0.3, 0.0, 0.33, 0.01, 0.24, 0.01, 0.71, 0.78, 0.29, 0.21, 0.01, 0.01, 0.23, 0.02, 0.37, 0.6, 0.19, 0.71, 0.25, 0.36, 0.58, 0.9, 0.41, 0.13, 0.39, 0.77, 0.45, 0.01, 0.78, 0.9, 0.19, 0.1, 0.57, 0.05, 0.18, 0.51, 0.68, 0.31, 0.01, 0.58, 0.75, 0.02, 0.05, 0.0, 0.01, 0.0, 0.18, 0.01, 0.34, 0.41, 0.0, 0.22, 0.17, 0.52, 0.02, 0.36, 0.17, 0.4, 0.0, 0.39, 0.01, 0.32, 0.02, 0.32, 0.17, 0.91, 0.33, 0.74, 0.23, 0.61, 0.3, 0.56, 0.0, 0.38, 0.02, 0.58, 0.18, 0.33, 0.04, 0.1, 0.01, 0.42, 0.75, 0.21, 0.56, 0.5, 0.59, 0.33, 0.6, 0.39, 0.4, 0.32, 0.59, 0.91, 0.5, 0.35, 0.25, 0.04, 0.15, 0.0, 0.05, 0.0, 0.22, 0.0, 0.2, 0.01, 0.47, 0.48, 0.64, 0.12, 0.48, 0.14, 0.29, 0.01, 0.17, 0.15, 0.57, 0.61, 0.69, 0.6, 0.75, 0.24, 0.87, 0.47, 0.73, 0.43, 0.53, 0.43, 0.51, 0.64, 0.08, 0.97, 0.77, 0.17, 0.81, 0.59, 0.06, 0.15, 0.22, 0.0, 0.29, 0.01, 0.24, 0.02, 0.65, 0.22, 0.64, 0.04, 0.63, 0.5, 0.62, 0.4, 0.29, 0.05, 0.22, 0.0, 0.17, 0.01, 0.3, 0.06, 0.61, 0.98, 0.76, 0.58, 0.26, 0.52, 0.24, 0.56, 0.11, 0.5, 0.0, 0.44, 0.02, 0.51, 0.74, 0.45, 0.9, 0.81, 0.83, 0.84, 0.69, 0.85, 0.54, 0.71, 0.81, 0.42, 0.62, 0.67, 0.67, 0.55, 0.57, 0.44, 0.45, 0.5, 0.61, 0.69, 0.62, 0.54, 0.39, 0.58, 0.42, 0.56, 0.53, 0.64, 0.53, 0.72, 0.79, 0.49, 0.73, 0.73, 0.33, 0.7, 0.76, 0.7, 0.66, 0.74, 0.78, 0.79, 0.67, 0.62, 0.73, 0.78, 0.73, 0.71, 0.79, 0.74, 0.81, 0.91, 0.89, 0.8, 0.9, 0.95, 0.96, 0.96, 1.0, 0.95, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 88.240793
| 0.440552
| 2,425
|
O43791
|
Q9UBN7
|
28599312
|
UbiNet, UbiBrowser, 31181401
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
HDAC6
|
MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH
|
Homo sapiens
|
Cytoplasm, Cytoplasm, cytoskeleton, Nucleus, Perikaryon, Cell projection, dendrite, Cell projection, axon, Cell projection, cilium, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cytoskeleton, cilium basal body
|
Low tissue specificity
|
{'Ciliated cells': '10.8', 'Basal respiratory cells': '7.9', 'Club cells': '12.6', 'Ionocytes': '16.2', 'Mucus glandular cells': '11.2', 'Serous glandular cells': '11.8', 'Gastric mucus-secreting cells': '23.0', 'Proximal enterocytes': '16.2', 'Paneth cells': '16.0', 'Distal enterocytes': '18.2', 'Intestinal goblet cells': '12.2', 'Exocrine glandular cells': '-0.487', 'Basal prostatic cells': '14.2', 'Prostatic glandular cells': '14.3', 'Breast glandular cells': '0.643', 'Breast myoepithelial cells': '0.535', 'Glandular and luminal cells': '11.6', 'Secretory cells': '11.2', 'Basal keratinocytes': '8.7', 'Suprabasal keratinocytes': '8.8', 'Basal squamous epithelial cells': '7.5', 'Squamous epithelial cells': '7.8', 'Alveolar cells type 1': '0.155', 'Alveolar cells type 2': '-0.237', 'Salivary duct cells': '13.5', 'Ductal cells': '0.593', 'Hepatocytes': '0.540', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.411', 'Distal tubular cells': '15.4', 'Collecting duct cells': '15.6', 'Mesothelial cells': '0.496', 'Sertoli cells': '0.343', 'Granulosa cells': '11.5', 'Enteroendocrine cells': '12.9', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.192', 'Excitatory neurons': '14.7', 'Inhibitory neurons': '17.7', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '33.8', 'Bipolar cells': '29.1', 'Horizontal cells': '40.9', 'Astrocytes': '19.8', 'Oligodendrocyte precursor cells': '16.0', 'Oligodendrocytes': '17.7', 'Microglial cells': '9.8', 'Muller glia cells': '20.1', 'Schwann cells': '0.161', 'Spermatogonia': '0.216', 'Spermatocytes': '0.328', 'Early spermatids': '-0.343', 'Late spermatids': '-0.276', 'Oocytes': '7.4', 'Cytotrophoblasts': '10.9', 'Syncytiotrophoblasts': '8.6', 'Extravillous trophoblasts': '13.6', 'Endothelial cells': '10.1', 'Lymphatic endothelial cells': '16.5', 'Cardiomyocytes': '0.577', 'Skeletal myocytes': '-0.157', 'Smooth muscle cells': '12.2', 'Adipocytes': '10.6', 'Melanocytes': '-0.099', 'Fibroblasts': '10.2', 'Peritubular cells': '0.226', 'Endometrial stromal cells': '11.6', 'Ovarian stromal cells': '15.5', 'Undifferentiated cells': '12.0', 'T-cells': '9.9', 'B-cells': '12.3', 'Plasma cells': '13.2', 'Nk-cells': '13.3', 'Granulocytes': '7.3', 'Monocytes': '15.2', 'Macrophages': '12.3', 'Hofbauer cells': '9.9', 'Kupffer cells': '12.6', 'Dendritic cells': '18.7', 'Langerhans cells': '0.036', 'Erythroid cells': '0.140', 'Adipocytes (Subcutaneous)': '-0.020', 'Adipocytes (Visceral)': '-0.207', 'Breast glandular cells (progenitors)': '0.475', 'Adipocytes (Breast)': '-0.468', 'Colon enterocytes': '-0.091', 'Colon enteroendocrine cells': '0.196', 'Enteric glia cells': '0.612', 'Mitotic cells (Colon)': '-0.138', 'Mitotic cells (Heart)': '0.434', 'Podocytes': '-0.012', 'Ascending Loop of Henle cells': '0.400', 'Intercalated cells': '0.147', 'Cholangiocyte': '0.091', 'NK-cells (Liver)': '0.073', 'Respiratory ciliated cells': '0.093', 'Mitotic cells (Lung)': '-0.132', 'NK-cells (Lung)': '0.205', 'B-cells (Lung)': '0.008', 'Alpha cells': '0.439', 'Beta cells': '0.399', 'Prostate glandular cells': '-0.163', 'Prostate basal glandular cells': '0.152', 'Urothelial cells': '0.204', 'Keratinocyte (other)': '-0.184', 'Keratinocyte (granular)': '-0.211', 'Hair cortex cells': '0.060', 'Inner root sheath cells': '0.016', 'Outer root sheath cells': '0.279', 'Sebaceous gland cells': '0.125', 'Eccrine sweat gland cells': '0.237', 'Adipocytes (Skin)': '0.165', 'Mitotic cells (Skin)': '0.107', 'Parietal cells': '-0.520', 'Chief cells': '-0.551', 'Gastric mucous cells': '-0.269', 'Gastric enteroendocrine cells': '-0.346', 'Mitotic cells (Stomach)': '0.025', 'Parafollicular cells': '0.054', 'Thyroid glandular cells': '0.215', 'Mitotic cells (Thyroid)': '-0.065', 'Adrenal cortex cells': '0.213', 'Adrenal medulla cells': '0.017', 'Mitotic cells (Adrenal gland)': '0.207', 'Minor salivary glandular cells': '0.346', 'Minor salivary gland ductal cells': '0.364', 'Minor salivary gland basal cells': '0.141', 'Mitotic cells (Minor salivary gland)': '0.108', 'Adipocytes (Minor salivary gland)': '0.135', 'Somatotropes': '0.489', 'Lactotropes': '0.393', 'Gonadotropes': '0.120', 'Corticotropes': '0.049', 'Thyrotropes': '0.131', 'Undifferentiated cells (Pituitary gland)': '-0.183', 'Mitotic cells (Spleen)': '-0.308', 'Platelets': '-0.168', 'Erythrocytes': '-0.046', 'Hematopoietic stem cells': '-0.359', 'B-cells (Spleen)': '0.350', 'NK-cells (Spleen)': '0.308', 'Amygdala excitatory': '18.5', 'Cerebellar inhibitory': '23.1', 'Cge interneuron': '28.9', 'Deep-layer corticothalamic and 6b': '19.4', 'Deep-layer intratelencephalic': '20.1', 'Deep-layer near-projecting': '27.0', 'Eccentric medium spiny neuron': '20.1', 'Hippocampal ca1-3': '21.2', 'Hippocampal ca4': '17.0', 'Hippocampal dentate gyrus': '15.2', 'Lamp5-lhx6 and chandelier': '29.1', 'Lower rhombic lip': '22.1', 'Mammillary body': '20.0', 'Medium spiny neuron': '16.3', 'Mge interneuron': '25.3', 'Midbrain-derived inhibitory': '25.5', 'Miscellaneous': '21.7', 'Splatter': '24.8', 'Thalamic excitatory': '23.2', 'Upper rhombic lip': '27.0', 'Upper-layer intratelencephalic': '19.8', 'Astrocyte': '41.4', 'Bergmann glia': '21.2', 'Central nervous system macrophage': '24.8', 'Choroid plexus epithelial cell': '15.9', 'Committed oligodendrocyte precursor': '26.5', 'Ependymal cell': '19.8', 'Oligodendrocyte': '28.7', 'Oligodendrocyte precursor cell': '22.9', 'Endothelial cell': '16.2', 'Pericyte': '20.9', 'Vascular associated smooth muscle cell': '15.7', 'Fibroblast': '20.2', 'Leukocyte': '14.5', 'Basophil': '1.9', 'Eosinophil': '5.2', 'Neutrophil': '4.0', 'Classical monocyte': '20.1', 'Non-classical monocyte': '41.6', 'Intermediate monocyte': '25.8', 'T-reg': '7.1', 'GdT-cell': '3.9', 'MAIT T-cell': '7.7', 'Memory CD4 T-cell': '2.7', 'Naive CD4 T-cell': '33.3', 'Memory CD8 T-cell': '3.0', 'Naive CD8 T-cell': '38.3', 'Memory B-cell': '2.8', 'Naive B-cell': '32.8', 'Plasmacytoid DC': '29.4', 'Myeloid DC': '18.5', 'NK-cell': '37.4', 'Total PBMC': '12.9', 'Vd2 gdTCR': '9.3', 'Memory CD4 T-cell Th1\\/Th17': '31.4', 'Memory CD4 T-cell Th17': '39.0', 'Memory CD4 T-cell Th2': '37.8', 'Non-Vd2 gdTCR': '10.1', 'Memory CD4 T-cell Th1': '42.0', 'Memory CD4 T-cell TFH': '49.2', 'Terminal effector memory CD4 T-cell': '13.7', 'Central memory CD8 T-cell': '7.6', 'Effector memory CD8 T-cell': '10.0', 'Terminal effector memory CD8 T-cell': '9.0', 'Non-switched memory B-cell': '8.7', 'Plasmablast': '24.0', 'Switched memory B-cell': '9.1', 'Exhausted memory B-cell': '11.6', 'Progenitor cell': '23.9', 'Memory T-reg': '43.3', 'Naive CD4 T-cell activated': '12.0', 'Naive CD8 T-cell activated': '16.4', 'Naive T-reg': '38.0'}
|
3C5K, 3GV4, 3PHD, 5B8D, 5EDU, 5KH3, 5KH7, 5KH9, 5WBN, 5WPB, 6CE6, 6CE8, 6CEA, 6CEC, 6CED, 6CEE, 6CEF, 7ZYU, 8G43, 8G44, 8G45
|
{'Adipose Tissue': 33.461935215946845, 'Adrenal Gland': 29.810155038759692, 'Bladder': 42.69238095238095, 'Blood': 15.331007534983852, 'Blood Vessel': 42.330711610486894, 'Brain': 34.37277365632097, 'Breast': 40.165860566448806, 'Cervix Uteri': 78.02052631578948, 'Colon': 43.2788189987163, 'Esophagus': 37.98306782006921, 'Fallopian Tube': 67.52444444444444, 'Heart': 15.392581881533102, 'Kidney': 42.82033707865169, 'Liver': 47.46420353982301, 'Lung': 49.772370242214535, 'Muscle': 18.404261519302615, 'Nerve': 62.632972536348944, 'Ovary': 83.1768888888889, 'Pancreas': 14.43628048780488, 'Pituitary': 107.41731448763252, 'Prostate': 53.89877551020408, 'Salivary Gland': 30.517246913580244, 'Skin': 26.645258153676064, 'Small Intestine': 42.52299465240642, 'Spleen': 48.703443983402494, 'Stomach': 29.67899721448468, 'Testis': 95.55772853185594, 'Thyroid': 69.62781010719755, 'Uterus': 81.41077464788732, 'Vagina': 51.91108974358974}
|
[37.73, 37.75, 40.98, 40.72, 40.09, 47.81, 49.57, 51.65, 51.4, 52.39, 55.66, 52.6, 53.62, 55.16, 58.98, 65.73, 66.91, 69.09, 71.61, 75.54, 76.71, 80.63, 80.4, 79.89, 84.51, 86.55, 88.32, 91.29, 93.51, 93.62, 96.0, 96.98, 97.12, 97.97, 97.95, 98.55, 98.21, 97.85, 96.95, 96.82, 96.85, 93.06, 93.7, 92.27, 90.79, 94.61, 95.57, 97.17, 95.39, 97.71, 97.58, 97.49, 97.99, 98.32, 97.29, 97.01, 97.3, 94.22, 91.27, 84.76, 76.79, 78.41, 84.79, 89.54, 93.07, 96.07, 98.15, 98.32, 98.75, 98.48, 98.6, 98.36, 97.89, 97.45, 97.8, 97.63, 97.8, 97.7, 97.9, 97.9, 97.16, 97.82, 98.49, 98.38, 98.69, 98.7, 98.7, 98.71, 98.37, 97.72, 96.17, 93.57, 89.03, 85.96, 84.3, 88.21, 93.13, 94.55, 96.81, 97.62, 98.18, 98.49, 98.68, 98.77, 98.53, 98.63, 97.68, 94.7, 93.97, 94.37, 93.06, 96.11, 97.13, 95.88, 96.1, 97.3, 98.38, 98.17, 98.05, 96.37, 96.22, 96.49, 97.54, 96.84, 97.59, 95.79, 96.55, 94.38, 96.93, 97.65, 98.41, 98.16, 98.35, 98.08, 98.35, 98.51, 98.44, 98.31, 97.29, 96.94, 97.73, 97.59, 96.08, 95.95, 93.55, 95.47, 96.2, 95.68, 97.08, 96.74, 95.47, 95.24, 96.8, 97.77, 98.3, 98.34, 98.62, 98.54, 98.56, 98.44, 98.24, 97.83, 95.83, 93.38, 87.2, 81.04, 79.88, 79.98, 78.13, 76.04, 77.51, 71.42, 69.18, 60.03, 53.15, 51.66, 54.87, 58.46, 69.86, 70.09, 76.75, 85.74, 86.65, 90.81, 93.77, 96.26, 95.31, 94.08, 95.83, 96.83, 96.62, 96.75, 97.28, 95.92, 95.08, 95.91, 94.59, 92.78, 95.39, 96.94, 95.32, 95.33, 95.94, 96.54, 96.54, 97.39, 94.59, 92.57, 96.79, 96.26, 97.67, 97.63, 97.69, 97.4, 95.4, 96.03, 97.85, 97.71, 95.83, 97.52, 97.8, 98.05, 97.07, 95.63, 95.33, 94.19, 92.97, 92.65, 90.58, 87.16, 79.69, 71.29, 73.53, 72.81, 75.24, 72.4, 78.49, 86.97, 89.32, 93.42, 93.05, 93.77, 95.05, 93.18, 90.78, 96.43, 96.48, 97.66, 97.68, 98.43, 98.32, 98.14, 98.52, 98.57, 98.4, 98.27, 98.69, 98.58, 98.46, 97.64, 97.35, 97.18, 97.69, 96.24, 97.59, 97.99, 95.18, 96.74, 97.75, 98.03, 97.44, 98.06, 98.56, 98.62, 98.12, 98.25, 98.49, 98.11, 97.4, 97.69, 98.04, 98.41, 98.1, 98.28, 98.64, 98.56, 98.25, 98.31, 98.58, 98.34, 96.9, 96.04, 97.7, 94.71, 92.8, 91.79, 94.82, 96.82, 97.91, 97.73, 97.62, 98.1, 98.37, 97.94, 98.27, 98.5, 98.4, 98.03, 98.34, 98.14, 97.92, 98.06, 96.92, 97.73, 96.42, 96.26, 98.02, 98.25, 96.35, 95.36, 97.83, 97.79, 93.81, 95.71, 97.51, 93.81, 92.72, 93.28, 94.16, 94.28, 97.2, 97.43, 96.78, 97.68, 98.13, 97.73, 97.34, 98.07, 97.91, 97.9, 98.09, 97.93, 97.74, 97.75, 98.02, 97.56, 98.11, 97.93, 96.93, 95.85, 94.76, 93.97, 93.23, 92.5, 90.71, 87.96, 86.57, 83.73, 74.61, 60.17, 41.48, 40.99, 42.63, 44.53, 36.68, 40.27, 43.27, 41.92, 44.81, 43.65, 45.55, 44.95, 44.16, 55.94]
|
[0.97, 0.91, 0.93, 0.89, 0.68, 0.69, 0.6, 0.93, 0.79, 0.61, 0.86, 0.93, 0.73, 0.89, 0.98, 0.63, 0.91, 0.71, 0.5, 0.81, 0.65, 0.33, 0.66, 0.47, 0.52, 0.54, 0.61, 0.5, 0.51, 0.29, 0.77, 0.12, 0.61, 0.16, 0.65, 0.12, 0.45, 0.1, 0.66, 0.56, 0.06, 0.64, 0.73, 0.19, 0.84, 0.29, 0.56, 0.46, 0.4, 0.48, 0.39, 0.19, 0.58, 0.14, 0.68, 0.57, 0.07, 0.28, 0.43, 0.48, 0.87, 0.91, 0.24, 0.55, 0.17, 0.27, 0.0, 0.07, 0.01, 0.24, 0.0, 0.01, 0.06, 0.21, 0.01, 0.36, 0.34, 0.61, 0.58, 0.0, 0.45, 0.69, 0.28, 0.01, 0.0, 0.01, 0.14, 0.0, 0.11, 0.0, 0.38, 0.36, 0.15, 0.62, 0.6, 0.82, 0.37, 0.07, 0.56, 0.0, 0.33, 0.02, 0.25, 0.0, 0.01, 0.01, 0.13, 0.22, 0.76, 0.76, 0.55, 0.49, 0.44, 0.26, 0.46, 0.56, 0.3, 0.58, 0.03, 0.85, 0.7, 0.35, 0.2, 0.54, 0.0, 0.32, 0.58, 0.65, 0.4, 0.31, 0.31, 0.4, 0.18, 0.3, 0.42, 0.08, 0.08, 0.55, 0.29, 0.55, 0.36, 0.03, 0.46, 0.47, 0.87, 0.83, 0.33, 0.38, 0.04, 0.22, 0.28, 0.77, 0.2, 0.36, 0.0, 0.13, 0.0, 0.22, 0.0, 0.34, 0.0, 0.24, 0.06, 0.36, 0.52, 0.66, 0.6, 0.45, 0.66, 0.27, 0.75, 0.22, 0.75, 0.45, 0.52, 0.75, 0.96, 0.73, 0.84, 0.91, 0.88, 0.9, 0.77, 0.78, 0.63, 0.55, 0.3, 0.56, 0.52, 0.3, 0.06, 0.21, 0.26, 0.17, 0.85, 0.69, 0.43, 0.69, 0.85, 0.32, 0.47, 0.04, 0.12, 0.0, 0.03, 0.0, 0.68, 0.86, 0.41, 0.66, 0.12, 0.38, 0.0, 0.09, 0.21, 0.69, 0.17, 0.0, 0.26, 0.8, 0.36, 0.0, 0.57, 0.35, 0.0, 0.27, 0.39, 0.21, 0.15, 0.8, 0.53, 0.8, 0.51, 0.56, 0.34, 0.18, 0.67, 0.66, 0.34, 0.42, 0.02, 0.56, 0.02, 0.82, 0.64, 0.1, 0.73, 0.22, 0.7, 0.05, 0.0, 0.46, 0.08, 0.0, 0.0, 0.22, 0.05, 0.0, 0.02, 0.2, 0.19, 0.48, 0.17, 0.74, 0.35, 0.06, 0.73, 0.81, 0.14, 0.07, 0.5, 0.51, 0.0, 0.0, 0.3, 0.02, 0.01, 0.31, 0.56, 0.05, 0.41, 0.03, 0.61, 0.61, 0.0, 0.08, 0.35, 0.29, 0.0, 0.06, 0.64, 0.08, 0.1, 0.29, 0.74, 0.55, 0.14, 0.38, 0.24, 0.69, 0.26, 0.0, 0.01, 0.56, 0.07, 0.0, 0.2, 0.19, 0.01, 0.28, 0.78, 0.14, 0.54, 0.0, 0.66, 0.58, 0.01, 0.14, 0.56, 0.47, 0.0, 0.07, 0.49, 0.23, 0.03, 0.24, 0.79, 0.31, 0.38, 0.73, 0.54, 0.0, 0.5, 0.71, 0.04, 0.69, 0.06, 0.12, 0.5, 0.54, 0.0, 0.46, 0.81, 0.62, 0.31, 0.55, 0.55, 0.01, 0.28, 0.45, 0.31, 0.04, 0.69, 0.71, 0.28, 0.34, 0.48, 0.65, 0.78, 0.68, 0.72, 0.86, 0.94, 0.93, 0.83, 0.93, 0.91, 0.95, 0.91, 0.94, 0.91, 0.93, 0.95, 0.96]
|
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0.12, 0.02, 0.0, 0.0, 0.0, 0.01, 0.0, 0.3, 0.21, 0.5, 0.59, 0.02, 0.02, 0.12, 0.11, 0.0, 0.01, 0.04, 0.06, 0.0, 0.0, 0.03, 0.16, 0.0, 0.01, 0.0, 0.04, 0.0, 0.0, 0.05, 0.11, 0.0, 0.14, 0.01, 0.09, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.01, 0.53, 0.28, 0.11, 0.74, 0.41, 0.0, 0.35, 0.07, 0.47, 0.01, 0.05, 0.17, 0.37, 0.03, 0.0, 0.0, 0.06, 0.02, 0.01, 0.1, 0.08, 0.0, 0.08, 0.04, 0.04, 0.04, 0.12, 0.02, 0.35, 0.01, 0.0, 0.01, 0.0, 0.01, 0.0, 0.04, 0.0, 0.11, 0.25, 0.25, 0.52, 0.15, 0.0, 0.02, 0.33, 0.0, 0.0, 0.03, 0.16, 0.0, 0.01, 0.34, 0.03, 0.0, 0.09, 0.22, 0.13, 0.36, 0.04, 0.41, 0.65, 0.03, 0.77, 0.29, 0.9, 0.34, 0.53, 0.13, 0.29, 0.71, 0.33, 0.0, 0.07, 0.38, 0.03, 0.0, 0.25, 0.44, 0.0, 0.22, 0.48, 0.23, 0.0, 0.36, 0.7, 0.44, 0.06, 0.38, 0.05, 0.05, 0.42, 0.11, 0.49, 0.6, 0.5, 0.8, 0.9, 0.73, 0.9, 0.83, 0.83, 0.93, 0.6, 0.82, 0.83, 0.83, 0.86, 0.8, 0.93, 0.93, 0.96, 0.94, 0.98, 0.97, 0.97, 0.99, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.9, 0.96, 0.98, 0.94, 0.98, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 0.98, 1.0, 0.91, 1.0, 0.92, 0.97, 1.0, 0.87, 1.0, 0.83, 1.0, 0.79, 1.0, 0.95, 1.0, 0.98, 1.0, 0.99, 0.99, 1.0, 0.97, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 0.96, 0.99, 0.96, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.89, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.84, 1.0, 0.84, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.96, 0.99, 0.93, 0.98, 0.9, 0.99, 0.98, 0.84, 0.96, 0.88, 0.89, 0.89, 1.0, 0.93, 0.83, 0.96, 0.83, 0.97, 0.88, 0.96, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.84, 0.48, 0.43, 0.48, 0.83, 0.85, 0.6, 0.26, 0.28, 0.75, 1.0, 1.0, 0.69, 0.56, 0.97, 1.0, 0.97, 1.0, 0.97, 0.99, 1.0, 0.98, 0.69, 0.71, 0.67, 0.33, 0.6, 0.45, 0.87, 0.38, 0.29, 0.65, 0.69, 0.09, 0.6, 0.27, 0.15, 0.83, 0.27, 0.25, 0.47, 0.89, 0.32, 0.37, 0.97, 0.92, 0.43, 0.1, 0.43, 0.18, 0.71, 0.43, 0.53, 0.02, 0.68, 0.58, 0.46, 0.55, 0.2, 0.76, 0.64, 0.32, 0.04, 0.15, 0.01, 0.01, 0.0, 0.16, 0.37, 0.13, 0.41, 0.03, 0.11, 0.0, 0.03, 0.47, 0.72, 0.39, 0.61, 0.16, 0.16, 0.0, 0.3, 0.55, 0.15, 0.14, 0.8, 0.73, 0.39, 0.38, 0.24, 0.05, 0.0, 0.02, 0.0, 0.03, 0.05, 0.59, 0.67, 0.09, 0.16, 0.02, 0.19, 0.0, 0.14, 0.54, 0.3, 0.66, 0.2, 0.31, 0.02, 0.47, 0.38, 0.78, 0.54, 0.02, 0.35, 0.69, 0.05, 0.08, 0.21, 0.34, 0.0, 0.12, 0.44, 0.44, 0.43, 0.62, 0.79, 0.65, 0.63, 0.26, 0.8, 0.86, 0.7, 0.97]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 76.58084
| 0.437564
| 330
|
O43791
|
Q9UER7
|
nan, 16524876, E3Net, nan
|
degron_data, UbiNet, UbiBrowser, 31181401, degron_data
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
DAXX
|
MATANSIIVLDDDDEDEAAAQPGPSHPLPNAASPGAEAPSSSEPHGARGSSSSGGKKCYKLENEKLFEEFLELCKMQTADHPEVVPFLYNRQQRAHSLFLASAEFCNILSRVLSRARSRPAKLYVYINELCTVLKAHSAKKKLNLAPAATTSNEPSGNNPPTHLSLDPTNAENTASQSPRTRGSRRQIQRLEQLLALYVAEIRRLQEKELDLSELDDPDSAYLQEARLKRKLIRLFGRLCELKDCSSLTGRVIEQRIPYRGTRYPEVNRRIERLINKPGPDTFPDYGDVLRAVEKAAARHSLGLPRQQLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVSSTSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKICTLPSPPSPLASLAPVADSSTRVDSPSHGLVTSSLCIPSPARLSQTPHSQPPRPGTCKTSVATQCDPEEIIVLSDSD
|
Homo sapiens
|
Cytoplasm, Nucleus, nucleoplasm, Nucleus, PML body, Nucleus, nucleolus, Chromosome, centromere, Nucleus, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '14.6', 'Basal respiratory cells': '33.6', 'Club cells': '26.2', 'Ionocytes': '15.5', 'Mucus glandular cells': '28.1', 'Serous glandular cells': '19.4', 'Gastric mucus-secreting cells': '18.3', 'Proximal enterocytes': '20.6', 'Paneth cells': '21.8', 'Distal enterocytes': '23.2', 'Intestinal goblet cells': '25.1', 'Exocrine glandular cells': '-0.802', 'Basal prostatic cells': '21.9', 'Prostatic glandular cells': '15.6', 'Breast glandular cells': '0.585', 'Breast myoepithelial cells': '0.430', 'Glandular and luminal cells': '25.2', 'Secretory cells': '18.2', 'Basal keratinocytes': '47.4', 'Suprabasal keratinocytes': '46.4', 'Basal squamous epithelial cells': '48.1', 'Squamous epithelial cells': '42.1', 'Alveolar cells type 1': '0.083', 'Alveolar cells type 2': '-0.328', 'Salivary duct cells': '25.6', 'Ductal cells': '0.623', 'Hepatocytes': '0.196', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.140', 'Distal tubular cells': '18.4', 'Collecting duct cells': '11.7', 'Mesothelial cells': '0.566', 'Sertoli cells': '0.122', 'Granulosa cells': '18.5', 'Enteroendocrine cells': '23.5', 'Pancreatic endocrine cells': '34.0', 'Leydig cells': '0.027', 'Excitatory neurons': '3.6', 'Inhibitory neurons': '3.6', 'Cone photoreceptor cells': '6.8', 'Rod photoreceptor cells': '9.6', 'Bipolar cells': '8.2', 'Horizontal cells': '6.3', 'Astrocytes': '5.0', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '4.3', 'Microglial cells': '6.3', 'Muller glia cells': '10.2', 'Schwann cells': '-0.032', 'Spermatogonia': '0.216', 'Spermatocytes': '0.452', 'Early spermatids': '0.350', 'Late spermatids': '-0.028', 'Oocytes': '15.4', 'Cytotrophoblasts': '25.3', 'Syncytiotrophoblasts': '26.0', 'Extravillous trophoblasts': '38.5', 'Endothelial cells': '22.2', 'Lymphatic endothelial cells': '14.9', 'Cardiomyocytes': '0.427', 'Skeletal myocytes': '-0.357', 'Smooth muscle cells': '21.4', 'Adipocytes': '18.9', 'Melanocytes': '0.114', 'Fibroblasts': '23.2', 'Peritubular cells': '-0.026', 'Endometrial stromal cells': '56.5', 'Ovarian stromal cells': '16.5', 'Undifferentiated cells': '24.5', 'T-cells': '40.4', 'B-cells': '46.6', 'Plasma cells': '34.8', 'Nk-cells': '40.2', 'Granulocytes': '21.4', 'Monocytes': '25.6', 'Macrophages': '21.2', 'Hofbauer cells': '23.4', 'Kupffer cells': '18.2', 'Dendritic cells': '36.4', 'Langerhans cells': '0.352', 'Erythroid cells': '0.047', 'Adipocytes (Subcutaneous)': '-0.310', 'Adipocytes (Visceral)': '-0.372', 'Breast glandular cells (progenitors)': '0.436', 'Adipocytes (Breast)': '-0.477', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.175', 'Enteric glia cells': '0.113', 'Mitotic cells (Colon)': '-0.213', 'Mitotic cells (Heart)': '0.512', 'Podocytes': '-0.130', 'Ascending Loop of Henle cells': '0.438', 'Intercalated cells': '-0.084', 'Cholangiocyte': '0.386', 'NK-cells (Liver)': '-0.301', 'Respiratory ciliated cells': '-0.038', 'Mitotic cells (Lung)': '0.001', 'NK-cells (Lung)': '0.266', 'B-cells (Lung)': '0.057', 'Alpha cells': '0.392', 'Beta cells': '0.200', 'Prostate glandular cells': '-0.302', 'Prostate basal glandular cells': '0.170', 'Urothelial cells': '0.292', 'Keratinocyte (other)': '0.348', 'Keratinocyte (granular)': '0.144', 'Hair cortex cells': '-0.167', 'Inner root sheath cells': '-0.131', 'Outer root sheath cells': '-0.033', 'Sebaceous gland cells': '0.011', 'Eccrine sweat gland cells': '-0.272', 'Adipocytes (Skin)': '-0.212', 'Mitotic cells (Skin)': '0.213', 'Parietal cells': '-0.652', 'Chief cells': '-0.538', 'Gastric mucous cells': '-0.256', 'Gastric enteroendocrine cells': '-0.378', 'Mitotic cells (Stomach)': '0.173', 'Parafollicular cells': '0.045', 'Thyroid glandular cells': '0.274', 'Mitotic cells (Thyroid)': '0.054', 'Adrenal cortex cells': '0.402', 'Adrenal medulla cells': '-0.098', 'Mitotic cells (Adrenal gland)': '0.123', 'Minor salivary glandular cells': '0.620', 'Minor salivary gland ductal cells': '-0.070', 'Minor salivary gland basal cells': '0.370', 'Mitotic cells (Minor salivary gland)': '0.466', 'Adipocytes (Minor salivary gland)': '0.193', 'Somatotropes': '0.176', 'Lactotropes': '-0.003', 'Gonadotropes': '-0.031', 'Corticotropes': '-0.019', 'Thyrotropes': '0.102', 'Undifferentiated cells (Pituitary gland)': '0.113', 'Mitotic cells (Spleen)': '-0.141', 'Platelets': '-0.149', 'Erythrocytes': '-0.135', 'Hematopoietic stem cells': '-0.269', 'B-cells (Spleen)': '0.611', 'NK-cells (Spleen)': '0.311', 'Amygdala excitatory': '4.2', 'Cerebellar inhibitory': '4.9', 'Cge interneuron': '6.9', 'Deep-layer corticothalamic and 6b': '4.6', 'Deep-layer intratelencephalic': '5.0', 'Deep-layer near-projecting': '4.8', 'Eccentric medium spiny neuron': '5.0', 'Hippocampal ca1-3': '5.5', 'Hippocampal ca4': '3.7', 'Hippocampal dentate gyrus': '4.1', 'Lamp5-lhx6 and chandelier': '5.5', 'Lower rhombic lip': '5.6', 'Mammillary body': '3.6', 'Medium spiny neuron': '3.8', 'Mge interneuron': '5.2', 'Midbrain-derived inhibitory': '5.6', 'Miscellaneous': '5.7', 'Splatter': '4.9', 'Thalamic excitatory': '5.1', 'Upper rhombic lip': '6.1', 'Upper-layer intratelencephalic': '4.7', 'Astrocyte': '5.4', 'Bergmann glia': '8.6', 'Central nervous system macrophage': '8.2', 'Choroid plexus epithelial cell': '7.2', 'Committed oligodendrocyte precursor': '6.6', 'Ependymal cell': '6.5', 'Oligodendrocyte': '8.2', 'Oligodendrocyte precursor cell': '6.0', 'Endothelial cell': '11.6', 'Pericyte': '9.8', 'Vascular associated smooth muscle cell': '8.3', 'Fibroblast': '7.6', 'Leukocyte': '25.0', 'Basophil': '30.9', 'Eosinophil': '47.7', 'Neutrophil': '48.3', 'Classical monocyte': '26.9', 'Non-classical monocyte': '43.2', 'Intermediate monocyte': '45.3', 'T-reg': '68.4', 'GdT-cell': '56.1', 'MAIT T-cell': '78.3', 'Memory CD4 T-cell': '48.8', 'Naive CD4 T-cell': '66.6', 'Memory CD8 T-cell': '62.0', 'Naive CD8 T-cell': '74.4', 'Memory B-cell': '59.0', 'Naive B-cell': '46.0', 'Plasmacytoid DC': '66.0', 'Myeloid DC': '43.0', 'NK-cell': '108.0', 'Total PBMC': '55.8', 'Vd2 gdTCR': '79.6', 'Memory CD4 T-cell Th1\\/Th17': '67.6', 'Memory CD4 T-cell Th17': '76.1', 'Memory CD4 T-cell Th2': '72.5', 'Non-Vd2 gdTCR': '87.3', 'Memory CD4 T-cell Th1': '80.0', 'Memory CD4 T-cell TFH': '93.4', 'Terminal effector memory CD4 T-cell': '87.6', 'Central memory CD8 T-cell': '59.3', 'Effector memory CD8 T-cell': '113.5', 'Terminal effector memory CD8 T-cell': '101.4', 'Non-switched memory B-cell': '79.0', 'Plasmablast': '145.9', 'Switched memory B-cell': '90.7', 'Exhausted memory B-cell': '96.0', 'Progenitor cell': '38.1', 'Memory T-reg': '108.9', 'Naive CD4 T-cell activated': '101.6', 'Naive CD8 T-cell activated': '122.8', 'Naive T-reg': '90.1'}
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2KQS, 2KZS, 2KZU, 4H9N, 4H9O, 4H9P, 4H9Q, 4H9R, 4H9S, 4HGA, 5GRQ, 5KDM, 5Y18, 5Y6O
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{'Adipose Tissue': 38.454609634551495, 'Adrenal Gland': 39.439302325581394, 'Bladder': 43.789523809523814, 'Blood': 38.0083638320775, 'Blood Vessel': 46.21025468164794, 'Brain': 19.853946631339895, 'Breast': 40.64925925925925, 'Cervix Uteri': 53.095263157894735, 'Colon': 38.35501925545571, 'Esophagus': 39.042027681660905, 'Fallopian Tube': 55.57444444444444, 'Heart': 13.64622531939605, 'Kidney': 20.36903370786517, 'Liver': 14.624884955752211, 'Lung': 43.16455017301038, 'Muscle': 24.232859277708595, 'Nerve': 44.942471728594505, 'Ovary': 43.55566666666667, 'Pancreas': 13.408676829268291, 'Pituitary': 36.71787985865724, 'Prostate': 41.84767346938776, 'Salivary Gland': 32.59475308641976, 'Skin': 44.8900221116639, 'Small Intestine': 45.176524064171126, 'Spleen': 66.05244813278009, 'Stomach': 28.977623955431756, 'Testis': 71.77290858725762, 'Thyroid': 46.904793261868306, 'Uterus': 57.70957746478874, 'Vagina': 43.92147435897436}
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41.02, 39.24, 45.06, 42.59, 41.9, 47.12, 41.69, 46.26, 40.39, 38.83, 36.49, 39.84, 38.47, 38.12, 37.06, 35.02, 36.46, 35.17, 34.83, 36.04, 36.55, 36.01, 37.23, 36.71, 35.22, 32.8, 33.8, 44.57, 47.05, 49.03, 48.04, 48.51, 45.24, 51.01, 50.45, 47.58, 47.85, 51.7, 48.37, 41.69, 38.73, 35.93, 39.09, 37.16, 41.5, 39.34, 41.56, 42.2, 38.74, 37.18, 40.31, 38.94, 35.47, 38.95, 39.39, 38.59, 37.55, 44.05, 39.93, 40.39, 39.28, 41.78, 38.25, 48.98, 40.53, 40.39, 39.12, 33.89, 35.63, 35.51, 38.34, 34.45, 37.78, 40.71, 39.93, 37.69, 36.67, 46.73, 38.4, 38.89, 38.51, 40.23, 38.42, 39.18, 39.59, 39.8, 41.15, 39.43, 40.86, 40.26, 36.21, 41.81, 35.1, 32.17, 38.0, 36.11, 37.39, 39.61, 30.26, 41.64, 37.02, 40.63, 40.94, 41.29, 41.49, 42.25, 40.47, 42.51, 42.94, 39.19, 50.62, 40.07, 51.09, 40.81, 44.97, 42.27, 38.01, 38.49, 31.16, 35.7, 33.21, 29.61, 32.32, 26.93, 33.91, 31.46, 36.18, 35.27, 31.87, 45.5, 37.08, 35.47, 36.04, 36.85, 34.04, 38.77, 39.82, 36.32, 46.45, 37.46, 35.41, 40.73, 39.31, 36.16, 45.29, 32.11, 36.51, 35.92, 36.62, 41.93, 40.69, 44.7, 38.31, 44.39, 37.17, 40.95, 40.56, 39.43, 40.3, 38.68, 41.02, 40.45, 35.51, 37.98, 34.47, 35.89, 37.12, 40.52, 41.76, 43.72, 41.35, 37.94, 39.78, 40.03, 39.31, 39.34, 32.53, 40.02, 39.7, 41.09, 39.65, 43.35, 40.35, 37.9, 41.65, 34.43, 49.62, 37.51, 40.56, 38.71, 37.18, 37.11, 39.04, 37.79, 58.48, 46.75, 40.04, 54.44, 39.85, 46.8, 44.52, 45.48, 40.93, 39.85, 39.5, 40.9, 37.85, 40.14, 40.3, 39.62, 45.13, 44.45, 50.6, 42.49, 44.23, 40.4, 42.21, 40.55, 42.93, 32.92, 39.81, 30.39, 40.41, 38.12, 39.58, 42.44, 39.38, 37.79, 41.67, 40.03, 41.81, 39.02, 35.09, 42.34, 41.14, 40.08, 46.22, 49.21, 39.04, 47.2, 40.78, 39.34, 34.27, 41.77, 37.56, 41.15, 39.78, 44.07, 36.29, 38.97, 37.64, 50.02, 41.94, 45.72, 40.37, 42.4, 51.81, 38.24, 47.53, 43.58, 41.87, 38.17, 33.91, 37.89, 41.85, 39.14, 38.21, 42.42, 44.34, 36.41, 55.05, 38.15, 35.18, 38.52, 37.31, 39.03, 38.22, 35.26, 40.88, 34.92, 38.0, 38.81, 37.2, 43.28, 40.88, 32.99, 37.39, 33.55, 38.51, 36.18, 37.04, 40.35, 36.84, 40.99, 34.5, 35.76, 41.27, 46.91, 50.97, 50.25, 45.7, 43.72, 44.04, 40.64, 37.26, 34.93, 38.69, 38.37]
|
[0.98, 0.96, 0.92, 0.89, 0.9, 0.84, 0.85, 0.81, 0.78, 0.86, 0.76, 0.91, 0.79, 0.96, 0.93, 0.97, 0.95, 0.94, 0.94, 0.9, 0.96, 0.98, 0.95, 0.93, 0.97, 0.96, 0.95, 0.97, 0.96, 0.94, 0.97, 0.97, 0.98, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 0.99, 0.85, 0.99, 0.84, 0.94, 0.98, 0.92, 0.97, 0.83, 0.92, 0.96, 0.86, 0.83, 0.71, 0.83, 0.38, 0.63, 0.18, 0.52, 0.77, 0.38, 0.01, 0.38, 0.73, 0.16, 0.04, 0.66, 0.46, 0.0, 0.09, 0.48, 0.2, 0.0, 0.51, 0.78, 0.39, 0.03, 0.71, 0.74, 0.48, 0.63, 0.64, 0.15, 0.18, 0.52, 0.56, 0.0, 0.51, 0.6, 0.18, 0.16, 0.64, 0.54, 0.13, 0.48, 0.69, 0.74, 0.06, 0.17, 0.23, 0.22, 0.36, 0.5, 0.01, 0.08, 0.57, 0.11, 0.0, 0.33, 0.34, 0.0, 0.02, 0.54, 0.45, 0.01, 0.52, 0.71, 0.59, 0.44, 0.97, 0.44, 0.02, 0.46, 0.63, 0.09, 0.07, 0.6, 0.24, 0.0, 0.11, 0.57, 0.19, 0.0, 0.62, 0.77, 0.3, 0.27, 0.48, 0.91, 0.82, 0.87, 0.79, 0.87, 0.84, 0.87, 0.94, 0.92, 0.88, 0.98, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.91, 1.0, 0.86, 0.93, 0.94, 0.89, 0.9, 0.97, 0.98, 0.98, 0.94, 0.97, 0.81, 0.88, 0.94, 0.85, 0.87, 0.81, 0.9, 0.86, 0.22, 0.48, 0.84, 0.75, 0.29, 0.14, 0.54, 0.63, 0.18, 0.43, 0.55, 0.34, 0.21, 0.52, 0.64, 0.24, 0.36, 0.51, 0.37, 0.08, 0.32, 0.5, 0.07, 0.22, 0.57, 0.55, 0.89, 0.36, 0.51, 0.82, 0.66, 0.38, 0.6, 0.82, 0.46, 0.75, 0.54, 0.07, 0.14, 0.62, 0.41, 0.36, 0.1, 0.33, 0.42, 0.14, 0.42, 0.57, 0.51, 0.18, 0.66, 0.61, 0.12, 0.3, 0.24, 0.4, 0.07, 0.11, 0.65, 0.13, 0.44, 0.65, 0.59, 0.6, 0.66, 0.66, 0.58, 0.8, 0.38, 0.09, 0.35, 0.4, 0.59, 0.62, 0.1, 0.59, 0.03, 0.87, 0.6, 0.14, 0.96, 0.28, 0.55, 0.27, 0.0, 0.09, 0.55, 0.23, 0.0, 0.14, 0.56, 0.18, 0.0, 0.28, 0.62, 0.93, 0.69, 0.74, 0.89, 0.17, 0.47, 0.09, 0.59, 0.32, 0.39, 0.24, 0.0, 0.15, 0.52, 0.08, 0.0, 0.35, 0.37, 0.05, 0.08, 0.68, 0.67, 0.51, 0.78, 0.25, 0.85, 0.16, 0.56, 0.63, 0.74, 0.42, 0.1, 0.25, 0.57, 0.13, 0.0, 0.46, 0.5, 0.0, 0.34, 0.64, 0.4, 0.0, 0.13, 0.55, 0.4, 0.02, 0.6, 0.57, 0.15, 0.55, 0.47, 0.29, 0.09, 0.44, 0.57, 0.55, 0.54, 0.54, 0.82, 0.26, 0.24, 0.62, 0.45, 0.55, 0.62, 0.6, 0.63, 0.5, 0.8, 0.71, 0.46, 0.56, 0.16, 0.6, 0.79, 0.44, 0.71, 0.73, 0.35, 0.22, 0.61, 0.59, 0.45, 0.67, 0.44, 0.37, 0.47, 0.57, 0.63, 0.43, 0.32, 0.5, 0.54, 0.41, 0.59, 0.54, 0.47, 0.68, 0.47, 0.59, 0.66, 0.44, 0.52, 0.49, 0.58, 0.6, 0.66, 0.55, 0.37, 0.5, 0.45, 0.51, 0.59, 0.56, 0.59, 0.63, 0.68, 0.57, 0.67, 0.73, 0.74, 0.68, 0.78, 0.78, 0.85, 0.98, 0.94, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.96, 1.0, 0.94, 0.97, 0.9, 0.88, 0.93, 0.9, 0.95, 0.88, 0.79, 0.7, 0.8, 0.72, 0.58, 0.8, 0.75, 0.86, 0.86, 0.85, 0.88, 0.82, 0.94, 0.92, 0.99, 0.79, 0.91, 0.94, 0.83, 0.6, 0.78, 0.9, 0.78, 0.59, 0.82, 0.91, 0.64, 0.9, 0.91, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.98, 0.97, 0.91, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 0.91, 1.0, 0.71, 1.0, 0.9, 1.0, 0.99, 0.99, 0.99, 1.0, 0.96, 1.0, 0.97, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.99, 1.0, 0.98, 1.0, 0.89, 0.87, 0.78, 0.74, 0.79, 0.87, 0.87, 0.89, 0.84, 0.93, 0.84, 0.92, 0.82, 0.84, 0.77, 0.74, 0.84, 0.81, 0.89, 0.83, 0.88, 0.86, 0.92, 0.87, 0.95, 0.84, 0.99, 0.99, 1.0, 0.99, 0.96, 1.0, 0.92, 1.0, 0.92, 0.98, 0.96, 0.99, 0.97, 0.99, 0.94, 0.96, 0.99, 0.92, 0.96, 0.95, 0.91, 0.94, 0.96, 1.0, 1.0, 1.0, 1.0, 0.9, 0.94, 0.94, 0.86, 0.98, 0.95, 1.0, 0.99, 1.0, 0.88, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.95, 0.99, 0.91, 0.95, 0.96, 0.95, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.95, 1.0, 0.94, 1.0, 0.95, 1.0, 0.91, 0.82, 1.0, 0.82, 1.0, 0.93, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.98, 0.99, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 0.99, 0.89, 0.9, 0.93, 0.96, 0.99, 0.99, 0.97, 0.98, 0.95, 0.98, 0.96, 0.96, 0.93, 0.88, 0.93, 0.86, 0.95, 0.93, 0.94, 0.89, 0.92, 0.94, 0.94, 0.98, 1.0, 0.98, 1.0, 0.96, 1.0, 0.96, 1.0, 0.98, 0.94, 0.97, 0.96, 0.89, 0.83, 0.85, 0.79, 0.8, 0.76, 0.88, 0.61, 0.86, 0.68, 0.82, 0.8, 0.52, 0.72, 0.82, 0.52, 0.42, 0.71, 0.67, 0.55, 0.73, 0.7, 0.88, 1.0]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 62.704716
| 0.725743
| 919
|
O43791
|
Q9Y6Q9
|
nan, 21577200, nan
|
degron_data, UbiNet, UbiBrowser, 31181401, degron_data
|
SPOP
|
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
|
Homo sapiens
|
Nucleus, Nucleus speckle, Cytoplasm
|
Low tissue specificity
|
{'Ciliated cells': '32.3', 'Basal respiratory cells': '25.8', 'Club cells': '36.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '29.6', 'Serous glandular cells': '41.9', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '36.2', 'Paneth cells': '35.0', 'Distal enterocytes': '26.7', 'Intestinal goblet cells': '46.0', 'Exocrine glandular cells': '-0.621', 'Basal prostatic cells': '38.0', 'Prostatic glandular cells': '63.4', 'Breast glandular cells': '0.481', 'Breast myoepithelial cells': '0.548', 'Glandular and luminal cells': '30.1', 'Secretory cells': '40.9', 'Basal keratinocytes': '40.0', 'Suprabasal keratinocytes': '41.5', 'Basal squamous epithelial cells': '30.8', 'Squamous epithelial cells': '27.7', 'Alveolar cells type 1': '0.215', 'Alveolar cells type 2': '-0.095', 'Salivary duct cells': '31.6', 'Ductal cells': '0.599', 'Hepatocytes': '0.529', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '18.4', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.442', 'Sertoli cells': '0.577', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '43.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.623', 'Excitatory neurons': '48.8', 'Inhibitory neurons': '48.0', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '58.0', 'Bipolar cells': '66.4', 'Horizontal cells': '48.5', 'Astrocytes': '76.5', 'Oligodendrocyte precursor cells': '50.9', 'Oligodendrocytes': '45.9', 'Microglial cells': '43.8', 'Muller glia cells': '96.6', 'Schwann cells': '0.188', 'Spermatogonia': '0.593', 'Spermatocytes': '0.277', 'Early spermatids': '-0.375', 'Late spermatids': '-0.656', 'Oocytes': '11.8', 'Cytotrophoblasts': '23.7', 'Syncytiotrophoblasts': '44.0', 'Extravillous trophoblasts': '23.8', 'Endothelial cells': '57.2', 'Lymphatic endothelial cells': '34.7', 'Cardiomyocytes': '0.636', 'Skeletal myocytes': '0.013', 'Smooth muscle cells': '66.7', 'Adipocytes': '53.4', 'Melanocytes': '0.119', 'Fibroblasts': '57.8', 'Peritubular cells': '0.568', 'Endometrial stromal cells': '38.6', 'Ovarian stromal cells': '56.4', 'Undifferentiated cells': '40.2', 'T-cells': '47.0', 'B-cells': '54.6', 'Plasma cells': '62.0', 'Nk-cells': '38.1', 'Granulocytes': '47.7', 'Monocytes': '68.1', 'Macrophages': '48.3', 'Hofbauer cells': '40.0', 'Kupffer cells': '52.4', 'Dendritic cells': '82.7', 'Langerhans cells': '0.338', 'Erythroid cells': '-0.008', 'Adipocytes (Subcutaneous)': '-0.568', 'Adipocytes (Visceral)': '-0.479', 'Breast glandular cells (progenitors)': '0.332', 'Adipocytes (Breast)': '-0.546', 'Colon enterocytes': '-0.194', 'Colon enteroendocrine cells': '0.201', 'Enteric glia cells': '0.086', 'Mitotic cells (Colon)': '-0.290', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.001', 'Ascending Loop of Henle cells': '0.481', 'Intercalated cells': '0.050', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '-0.097', 'NK-cells (Lung)': '0.093', 'B-cells (Lung)': '-0.136', 'Alpha cells': '0.433', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.154', 'Prostate basal glandular cells': '-0.194', 'Urothelial cells': '-0.320', 'Keratinocyte (other)': '0.239', 'Keratinocyte (granular)': '-0.254', 'Hair cortex cells': '0.002', 'Inner root sheath cells': '0.040', 'Outer root sheath cells': '0.293', 'Sebaceous gland cells': '0.058', 'Eccrine sweat gland cells': '0.155', 'Adipocytes (Skin)': '-0.055', 'Mitotic cells (Skin)': '0.424', 'Parietal cells': '-0.669', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.543', 'Gastric enteroendocrine cells': '-0.472', 'Mitotic cells (Stomach)': '-0.131', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.350', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.646', 'Adrenal medulla cells': '0.101', 'Mitotic cells (Adrenal gland)': '0.462', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '0.118', 'Mitotic cells (Minor salivary gland)': '0.182', 'Adipocytes (Minor salivary gland)': '0.148', 'Somatotropes': '-0.107', 'Lactotropes': '-0.150', 'Gonadotropes': '-0.018', 'Corticotropes': '-0.212', 'Thyrotropes': '0.059', 'Undifferentiated cells (Pituitary gland)': '0.485', 'Mitotic cells (Spleen)': '-0.223', 'Platelets': '-0.156', 'Erythrocytes': '-0.190', 'Hematopoietic stem cells': '-0.255', 'B-cells (Spleen)': '0.358', 'NK-cells (Spleen)': '0.390', 'Amygdala excitatory': '82.1', 'Cerebellar inhibitory': '106.7', 'Cge interneuron': '75.3', 'Deep-layer corticothalamic and 6b': '111.7', 'Deep-layer intratelencephalic': '76.6', 'Deep-layer near-projecting': '118.4', 'Eccentric medium spiny neuron': '90.3', 'Hippocampal ca1-3': '75.3', 'Hippocampal ca4': '91.9', 'Hippocampal dentate gyrus': '101.9', 'Lamp5-lhx6 and chandelier': '77.5', 'Lower rhombic lip': '80.7', 'Mammillary body': '88.4', 'Medium spiny neuron': '92.5', 'Mge interneuron': '78.8', 'Midbrain-derived inhibitory': '81.9', 'Miscellaneous': '67.8', 'Splatter': '79.0', 'Thalamic excitatory': '81.7', 'Upper rhombic lip': '135.3', 'Upper-layer intratelencephalic': '77.0', 'Astrocyte': '132.8', 'Bergmann glia': '80.7', 'Central nervous system macrophage': '108.7', 'Choroid plexus epithelial cell': '179.0', 'Committed oligodendrocyte precursor': '83.5', 'Ependymal cell': '162.6', 'Oligodendrocyte': '82.1', 'Oligodendrocyte precursor cell': '89.5', 'Endothelial cell': '146.2', 'Pericyte': '76.0', 'Vascular associated smooth muscle cell': '80.4', 'Fibroblast': '96.0', 'Leukocyte': '93.7', 'Basophil': '92.8', 'Eosinophil': '93.0', 'Neutrophil': '168.7', 'Classical monocyte': '27.8', 'Non-classical monocyte': '34.0', 'Intermediate monocyte': '100.8', 'T-reg': '77.8', 'GdT-cell': '61.2', 'MAIT T-cell': '84.3', 'Memory CD4 T-cell': '66.0', 'Naive CD4 T-cell': '61.2', 'Memory CD8 T-cell': '68.8', 'Naive CD8 T-cell': '52.1', 'Memory B-cell': '76.5', 'Naive B-cell': '48.4', 'Plasmacytoid DC': '106.7', 'Myeloid DC': '155.2', 'NK-cell': '37.5', 'Total PBMC': '90.9', 'Vd2 gdTCR': '95.7', 'Memory CD4 T-cell Th1\\/Th17': '49.2', 'Memory CD4 T-cell Th17': '44.8', 'Memory CD4 T-cell Th2': '52.1', 'Non-Vd2 gdTCR': '99.3', 'Memory CD4 T-cell Th1': '47.1', 'Memory CD4 T-cell TFH': '45.8', 'Terminal effector memory CD4 T-cell': '97.8', 'Central memory CD8 T-cell': '91.8', 'Effector memory CD8 T-cell': '91.2', 'Terminal effector memory CD8 T-cell': '81.7', 'Non-switched memory B-cell': '117.0', 'Plasmablast': '128.5', 'Switched memory B-cell': '109.1', 'Exhausted memory B-cell': '95.6', 'Progenitor cell': '98.4', 'Memory T-reg': '38.3', 'Naive CD4 T-cell activated': '48.6', 'Naive CD8 T-cell activated': '53.8', 'Naive T-reg': '50.4'}
|
2CR2, 3HQH, 3HQI, 3HQL, 3HQM, 3HSV, 3HTM, 3HU6, 3IVB, 3IVQ, 3IVV, 4EOZ, 4HS2, 4J8Z, 4O1V, 6F8F, 6F8G, 6I41, 6I5P, 6I68, 6I7A, 7D3D, 7KLZ, 7LIN, 7LIO, 7LIP, 7LIQ, 8DWS, 8DWT, 8DWU, 8DWV
|
{'Adipose Tissue': 33.43968106312292, 'Adrenal Gland': 20.745782945736437, 'Bladder': 57.80761904761905, 'Blood': 17.309505597416575, 'Blood Vessel': 70.3903670411985, 'Brain': 25.59418168054504, 'Breast': 33.54710239651416, 'Cervix Uteri': 56.43578947368421, 'Colon': 81.79991014120667, 'Esophagus': 55.67932802768166, 'Fallopian Tube': 50.629999999999995, 'Heart': 15.31364912891986, 'Kidney': 14.822640449438202, 'Liver': 12.763300884955752, 'Lung': 38.426972318339104, 'Muscle': 19.152377334993773, 'Nerve': 42.35045234248789, 'Ovary': 45.32711111111111, 'Pancreas': 10.023838414634149, 'Pituitary': 32.932438162544166, 'Prostate': 57.1014693877551, 'Salivary Gland': 23.114074074074075, 'Skin': 26.406306246545057, 'Small Intestine': 39.52465240641711, 'Spleen': 28.06435684647303, 'Stomach': 35.08571030640669, 'Testis': 20.034515235457064, 'Thyroid': 39.005666156202146, 'Uterus': 70.4919014084507, 'Vagina': 44.44339743589744}
|
NCOA3
|
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNGVSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGSSMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQFAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC
|
Homo sapiens
|
Cytoplasm, Nucleus
|
Low tissue specificity
|
{'Ciliated cells': '34.9', 'Basal respiratory cells': '24.9', 'Club cells': '37.3', 'Ionocytes': '33.5', 'Mucus glandular cells': '43.8', 'Serous glandular cells': '35.4', 'Gastric mucus-secreting cells': '22.4', 'Proximal enterocytes': '7.5', 'Paneth cells': '19.4', 'Distal enterocytes': '16.2', 'Intestinal goblet cells': '13.5', 'Exocrine glandular cells': '-0.582', 'Basal prostatic cells': '32.3', 'Prostatic glandular cells': '23.7', 'Breast glandular cells': '0.150', 'Breast myoepithelial cells': '0.063', 'Glandular and luminal cells': '76.0', 'Secretory cells': '21.4', 'Basal keratinocytes': '33.6', 'Suprabasal keratinocytes': '40.7', 'Basal squamous epithelial cells': '65.8', 'Squamous epithelial cells': '64.1', 'Alveolar cells type 1': '0.282', 'Alveolar cells type 2': '-0.180', 'Salivary duct cells': '31.1', 'Ductal cells': '0.620', 'Hepatocytes': '0.421', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.068', 'Distal tubular cells': '3.1', 'Collecting duct cells': '11.7', 'Mesothelial cells': '0.225', 'Sertoli cells': '0.327', 'Granulosa cells': '19.5', 'Enteroendocrine cells': '11.4', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.437', 'Excitatory neurons': '46.9', 'Inhibitory neurons': '61.7', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '23.8', 'Bipolar cells': '18.2', 'Horizontal cells': '11.3', 'Astrocytes': '26.3', 'Oligodendrocyte precursor cells': '46.2', 'Oligodendrocytes': '50.4', 'Microglial cells': '104.7', 'Muller glia cells': '10.2', 'Schwann cells': '0.151', 'Spermatogonia': '0.602', 'Spermatocytes': '0.553', 'Early spermatids': '-0.187', 'Late spermatids': '-0.465', 'Oocytes': '18.4', 'Cytotrophoblasts': '67.1', 'Syncytiotrophoblasts': '104.2', 'Extravillous trophoblasts': '25.3', 'Endothelial cells': '53.6', 'Lymphatic endothelial cells': '35.7', 'Cardiomyocytes': '0.510', 'Skeletal myocytes': '-0.181', 'Smooth muscle cells': '36.5', 'Adipocytes': '79.1', 'Melanocytes': '0.184', 'Fibroblasts': '31.8', 'Peritubular cells': '0.419', 'Endometrial stromal cells': '28.1', 'Ovarian stromal cells': '19.2', 'Undifferentiated cells': '9.8', 'T-cells': '49.0', 'B-cells': '155.2', 'Plasma cells': '161.2', 'Nk-cells': '34.3', 'Granulocytes': '18.4', 'Monocytes': '103.9', 'Macrophages': '65.6', 'Hofbauer cells': '24.8', 'Kupffer cells': '44.3', 'Dendritic cells': '64.4', 'Langerhans cells': '0.314', 'Erythroid cells': '0.017', 'Adipocytes (Subcutaneous)': '0.040', 'Adipocytes (Visceral)': '-0.318', 'Breast glandular cells (progenitors)': '0.085', 'Adipocytes (Breast)': '-0.067', 'Colon enterocytes': '-0.039', 'Colon enteroendocrine cells': '0.268', 'Enteric glia cells': '0.165', 'Mitotic cells (Colon)': '0.026', 'Mitotic cells (Heart)': '0.466', 'Podocytes': '-0.103', 'Ascending Loop of Henle cells': '0.443', 'Intercalated cells': '-0.051', 'Cholangiocyte': '0.368', 'NK-cells (Liver)': '-0.268', 'Respiratory ciliated cells': '0.001', 'Mitotic cells (Lung)': '-0.179', 'NK-cells (Lung)': '0.233', 'B-cells (Lung)': '0.064', 'Alpha cells': '0.427', 'Beta cells': '0.264', 'Prostate glandular cells': '-0.359', 'Prostate basal glandular cells': '0.188', 'Urothelial cells': '0.347', 'Keratinocyte (other)': '0.414', 'Keratinocyte (granular)': '0.060', 'Hair cortex cells': '-0.198', 'Inner root sheath cells': '-0.100', 'Outer root sheath cells': '-0.031', 'Sebaceous gland cells': '0.031', 'Eccrine sweat gland cells': '-0.202', 'Adipocytes (Skin)': '-0.141', 'Mitotic cells (Skin)': '0.320', 'Parietal cells': '-0.536', 'Chief cells': '-0.565', 'Gastric mucous cells': '-0.188', 'Gastric enteroendocrine cells': '-0.337', 'Mitotic cells (Stomach)': '0.135', 'Parafollicular cells': '0.026', 'Thyroid glandular cells': '0.137', 'Mitotic cells (Thyroid)': '0.160', 'Adrenal cortex cells': '0.448', 'Adrenal medulla cells': '-0.044', 'Mitotic cells (Adrenal gland)': '0.319', 'Minor salivary glandular cells': '0.554', 'Minor salivary gland ductal cells': '0.075', 'Minor salivary gland basal cells': '0.409', 'Mitotic cells (Minor salivary gland)': '0.497', 'Adipocytes (Minor salivary gland)': '0.197', 'Somatotropes': '-0.114', 'Lactotropes': '-0.263', 'Gonadotropes': '-0.021', 'Corticotropes': '-0.155', 'Thyrotropes': '0.053', 'Undifferentiated cells (Pituitary gland)': '0.339', 'Mitotic cells (Spleen)': '0.043', 'Platelets': '-0.184', 'Erythrocytes': '-0.128', 'Hematopoietic stem cells': '-0.296', 'B-cells (Spleen)': '0.500', 'NK-cells (Spleen)': '0.271', 'Amygdala excitatory': '69.8', 'Cerebellar inhibitory': '90.2', 'Cge interneuron': '86.6', 'Deep-layer corticothalamic and 6b': '47.7', 'Deep-layer intratelencephalic': '67.7', 'Deep-layer near-projecting': '34.8', 'Eccentric medium spiny neuron': '63.9', 'Hippocampal ca1-3': '51.2', 'Hippocampal ca4': '53.0', 'Hippocampal dentate gyrus': '83.3', 'Lamp5-lhx6 and chandelier': '83.9', 'Lower rhombic lip': '87.8', 'Mammillary body': '82.6', 'Medium spiny neuron': '42.5', 'Mge interneuron': '88.3', 'Midbrain-derived inhibitory': '173.4', 'Miscellaneous': '77.4', 'Splatter': '66.9', 'Thalamic excitatory': '69.0', 'Upper rhombic lip': '65.3', 'Upper-layer intratelencephalic': '64.9', 'Astrocyte': '68.3', 'Bergmann glia': '83.1', 'Central nervous system macrophage': '401.3', 'Choroid plexus epithelial cell': '39.1', 'Committed oligodendrocyte precursor': '77.5', 'Ependymal cell': '83.1', 'Oligodendrocyte': '102.4', 'Oligodendrocyte precursor cell': '88.1', 'Endothelial cell': '292.3', 'Pericyte': '133.2', 'Vascular associated smooth muscle cell': '140.8', 'Fibroblast': '129.3', 'Leukocyte': '361.2', 'Basophil': '100.3', 'Eosinophil': '3.0', 'Neutrophil': '100.7', 'Classical monocyte': '80.6', 'Non-classical monocyte': '149.1', 'Intermediate monocyte': '79.9', 'T-reg': '57.8', 'GdT-cell': '2.5', 'MAIT T-cell': '37.2', 'Memory CD4 T-cell': '2.3', 'Naive CD4 T-cell': '125.3', 'Memory CD8 T-cell': '2.2', 'Naive CD8 T-cell': '109.3', 'Memory B-cell': '9.3', 'Naive B-cell': '294.8', 'Plasmacytoid DC': '68.0', 'Myeloid DC': '76.0', 'NK-cell': '63.0', 'Total PBMC': '51.3', 'Vd2 gdTCR': '39.9', 'Memory CD4 T-cell Th1\\/Th17': '101.2', 'Memory CD4 T-cell Th17': '88.0', 'Memory CD4 T-cell Th2': '110.3', 'Non-Vd2 gdTCR': '48.0', 'Memory CD4 T-cell Th1': '109.3', 'Memory CD4 T-cell TFH': '96.0', 'Terminal effector memory CD4 T-cell': '62.1', 'Central memory CD8 T-cell': '63.7', 'Effector memory CD8 T-cell': '45.6', 'Terminal effector memory CD8 T-cell': '51.2', 'Non-switched memory B-cell': '179.9', 'Plasmablast': '337.5', 'Switched memory B-cell': '145.2', 'Exhausted memory B-cell': '155.0', 'Progenitor cell': '28.9', 'Memory T-reg': '112.6', 'Naive CD4 T-cell activated': '199.1', 'Naive CD8 T-cell activated': '183.8', 'Naive T-reg': '126.4'}
|
1KBH, 3L3X, 3L3Z, 6ES7, 6SQC
|
{'Adipose Tissue': 24.700320598006645, 'Adrenal Gland': 10.096647286821703, 'Bladder': 21.90209523809524, 'Blood': 27.6743670613563, 'Blood Vessel': 34.62546816479401, 'Brain': 4.992160484481453, 'Breast': 21.387257080610024, 'Cervix Uteri': 24.58157894736842, 'Colon': 15.763173299101412, 'Esophagus': 19.344323183391, 'Fallopian Tube': 23.10111111111111, 'Heart': 8.595555168408827, 'Kidney': 8.575426966292135, 'Liver': 5.412455752212389, 'Lung': 32.21031141868512, 'Muscle': 20.724861768368616, 'Nerve': 29.25163166397415, 'Ovary': 23.618055555555557, 'Pancreas': 6.076243902439025, 'Pituitary': 12.188851590106008, 'Prostate': 17.14431020408163, 'Salivary Gland': 16.913845679012347, 'Skin': 25.2099325594251, 'Small Intestine': 27.72657219251337, 'Spleen': 37.74410788381743, 'Stomach': 13.022869080779945, 'Testis': 12.485218836565096, 'Thyroid': 24.93074119448698, 'Uterus': 27.35957746478873, 'Vagina': 26.200403846153847}
|
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|
[1.0, 1.0, 1.0, 0.98, 0.99, 0.97, 1.0, 0.92, 0.92, 0.87, 0.91, 1.0, 0.99, 0.79, 1.0, 0.9, 1.0, 1.0, 1.0, 1.0, 0.96, 0.87, 0.94, 0.78, 0.96, 0.72, 0.83, 0.73, 0.84, 0.72, 0.67, 0.56, 0.51, 0.4, 0.57, 0.58, 0.71, 0.54, 0.5, 0.44, 0.48, 0.29, 0.54, 0.56, 0.1, 0.45, 0.33, 0.28, 0.2, 0.67, 0.45, 0.05, 0.45, 0.74, 0.78, 0.31, 0.88, 0.57, 0.72, 0.86, 0.86, 0.33, 0.85, 0.86, 0.83, 0.35, 0.71, 0.36, 0.54, 0.41, 0.03, 0.46, 0.62, 0.19, 0.17, 0.64, 0.49, 0.16, 0.58, 0.68, 0.4, 0.65, 0.71, 0.54, 0.43, 0.59, 0.7, 0.63, 0.77, 0.64, 0.6, 0.42, 0.71, 0.93, 0.68, 0.82, 0.9, 0.44, 0.65, 0.85, 0.85, 0.76, 0.67, 0.69, 0.95, 0.92, 0.94, 0.57, 0.72, 0.6, 0.82, 0.42, 0.31, 0.45, 0.57, 0.46, 0.53, 0.13, 0.73, 0.76, 0.43, 0.34, 0.0, 0.02, 0.29, 0.02, 0.15, 0.0, 0.23, 0.39, 0.66, 0.0, 0.4, 0.02, 0.34, 0.29, 0.02, 0.13, 0.73, 0.2, 0.0, 0.43, 0.82, 0.08, 0.0, 0.46, 0.17, 0.5, 0.32, 0.7, 0.35, 0.02, 0.32, 0.81, 0.27, 0.22, 0.01, 0.23, 0.63, 0.06, 0.0, 0.22, 0.69, 0.52, 0.13, 0.29, 0.76, 0.48, 0.01, 0.53, 0.64, 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0.64, 0.7, 0.8]
|
BTB
|
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex
|
BCR
| null |
GLI2, GLI3, SPOPL,BTB,CUL3,RBX1
|
BRMS1, DAXX, PDX1/IPF1, GLI2 , GLI3, MACROH2A1, BMI1,PDX1
| null | null | null |
Homodimer, homooligomer
| null | 89.872112
| 0.406765
| 47.82283
| 0.791454
| 226
|
O44382
|
O97143
|
22199232, 34718738
|
UbiNet, UbiBrowser, Degronopedia
|
slmb
|
MMKMETDKIMDETNSNAQAFTTTMLYDPVRKKDSSPTYQTERELCFQYFTQWSESGQVDFVEHLLSRMCHYQHGQINAYLKPMLQRDFITLLPIKGLDHIGENILSYLDAESLKSSELVCKEWLRVISEGMLWKKLIERKVRTDSLWRGLAERRNWMQYLFKPRPGQTQRPHSFHRELFPKIMNDIDSIENNWRTGRHMLRRINCRSENSKGVYCLQYDDGKIVSGLRDNTIKIWDRTDLQCVKTLMGHTGSVLCLQYDDKVIISGSSDSTVRVWDVNTGEMVNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMTSPSEITLRRVLVGHRAAVNVVDFDEKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNSIRLWDIECGACLRVLEGHEELVRCIRFDTKRIVSGAYDGKIKVWDLVAALDPRAASNTLCLNTLVEHTGRVFRLQFDEFQIVSSSHDDTILIWDFLNFTPNENKTGRTPSPALMEH
|
Drosophila melanogaster
| null |
Not found
|
{}
| null |
{}
|
SAK
|
MLSNRAFGETIEDYEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSHGLPADVWSVGCMLYTLLVGRPPFETDAVQSTLNKVVMSEYIMPAHLSYEAQDLINKLLKKLPHERITLEAVLCHPFMLKCSNGGHSAPGALNVFSQSMESGDSGIITFASSDSRNSQQIRSVENSGPQQVLPQIREEFKQVHHKLPYEQTGLFGQASTGLAEPNWPGAAKSSAFCMEAGNVPNSKQASLKEDRISVPPLNTKRLLPTRYKTKNAIMSILRNGEVVLEFLKFRPTYNEDRINDICRISDDGQRIIIYQPDPGRGLPVREQPPDLQIPSGDCVYNYDNLPSKHWKKYIYGARFVGLVKSKTPKVTYFSTLGKCQLMETMTDFEIRFYSGAKLLKTPSEGLKVYDRNGMLLSDYSCSESRSLIEHGNECFTHCVNISNALEVAQTKDNSCFPVTIGRRPITDVQPAQRLDGLRDTTNIAFSTPKSNQGSINFSLSTISSTRNTSDFGTNCSRSNMLAAHQNIPIKRINVPEIGIATELSHGVVQVQFYDGSVVSVIPSMQGGGITYTQPNGTSTHFGKGDDLPFPVRDRVGQIPNIQLKLKTAPLLGSGRKTDYNNAMTPKTTTPYYNRMLL
|
Drosophila melanogaster
|
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
|
Not found
|
{}
|
4G7N, 4NK7, 5LHX, 7RL3
|
{}
|
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|
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|
[36.94, 45.97, 40.04, 52.01, 59.21, 83.2, 89.58, 88.61, 91.04, 93.75, 93.44, 93.54, 95.05, 96.41, 95.89, 93.32, 92.24, 89.69, 89.81, 85.64, 78.49, 76.14, 66.25, 65.22, 75.2, 82.47, 87.56, 92.06, 94.09, 95.61, 96.43, 96.7, 95.94, 94.77, 91.87, 92.65, 93.08, 93.7, 95.7, 96.26, 96.31, 95.55, 93.26, 92.6, 89.25, 87.04, 86.61, 83.58, 74.77, 72.82, 70.31, 59.69, 59.84, 63.1, 69.05, 74.02, 73.09, 72.03, 78.16, 83.55, 81.54, 84.93, 86.69, 88.58, 88.39, 91.97, 90.8, 90.29, 93.42, 94.34, 96.22, 96.06, 96.77, 96.41, 95.77, 94.95, 94.19, 93.16, 93.08, 93.1, 93.45, 92.33, 92.17, 90.81, 89.71, 91.39, 91.09, 93.74, 93.44, 94.96, 95.11, 95.1, 95.86, 95.13, 92.77, 92.2, 91.58, 91.52, 93.49, 90.62, 88.99, 91.15, 91.18, 88.12, 88.39, 90.72, 89.34, 92.26, 91.66, 94.37, 95.49, 96.71, 95.4, 94.87, 96.63, 97.19, 95.88, 96.82, 97.56, 97.31, 97.63, 97.72, 97.76, 97.18, 96.98, 96.79, 96.81, 96.94, 94.82, 93.76, 93.43, 90.94, 89.16, 90.16, 89.35, 90.27, 86.43, 86.92, 93.28, 90.8, 91.57, 87.3, 92.41, 95.57, 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88.35, 85.82, 83.74, 82.42, 74.55, 79.95, 79.63, 84.35, 88.66, 89.66, 90.02, 93.03, 94.77, 92.85, 89.49, 87.82, 87.46, 80.55, 73.3, 54.03, 38.99, 35.1, 32.31, 30.11, 33.03, 34.9, 29.3, 32.74, 32.98, 30.04, 36.0, 31.54, 26.86, 28.9, 30.15, 27.95, 29.24, 28.19, 27.23, 27.14, 28.63, 29.58, 28.33, 30.33, 26.91, 29.8, 24.7, 28.25, 24.37, 26.05, 24.0, 27.27, 25.54, 28.37, 28.36, 25.57, 29.44, 27.59, 29.78, 29.13, 29.25, 27.85, 29.06, 26.82, 29.18, 26.38, 27.58, 25.76, 25.19, 24.77, 24.14, 25.74, 28.1, 28.23, 27.89, 27.12, 27.88, 36.86, 45.27, 59.7, 74.29, 80.8, 83.89, 86.39, 88.53, 90.14, 88.73, 86.78, 81.84, 82.84, 85.08, 88.46, 90.92, 92.05, 90.76, 87.7, 86.72, 75.76, 75.06, 80.72, 87.67, 89.68, 92.13, 92.4, 92.33, 91.47, 88.61, 86.49, 82.61, 89.89, 92.62, 92.38, 91.66, 89.92, 87.43, 82.98, 78.12, 75.39, 70.92, 71.58, 79.98, 87.52, 88.39, 90.9, 91.36, 90.16, 87.06, 83.87, 81.23, 76.41, 77.9, 85.71, 86.45, 89.66, 88.41, 84.16, 74.92, 77.14, 82.2, 83.04, 85.01, 85.29, 83.27, 79.04, 87.17, 88.3, 87.52, 88.36, 86.85, 86.02, 86.24, 85.4, 85.72, 86.57, 86.94, 84.37, 86.1, 84.62, 83.61, 81.9, 80.98, 78.95, 74.95, 75.92, 68.38, 45.32, 37.91, 32.3, 32.7, 27.58, 34.47, 33.49, 27.77, 34.27, 34.06, 32.82, 31.94, 32.99, 28.36, 33.71, 30.72, 32.8, 29.51, 35.75, 33.13, 30.53, 33.82, 31.51, 32.02, 33.34, 33.26]
|
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| null | null | null | null | null | null | null | null | null | null | null | 85.88502
| 0.375667
| 73.119454
| 0.460832
| 864
|
O55176
|
Q60857
|
31891772
|
UbiBrowser
|
Pja1
|
MSHQERIASQRRTTAEVPMHRSTANQSKRSRSPFASTRRRWDDSESSGASLAVESEDYSRYPPREYRASGSRRGLAYGHIDTVVARDSEEEGAGPVDRLPVRGKAGKFKDDPEKGARSSRFTSVNHDAKEECGKVESPPAARCSARRAELSKQNGSSASQISSAEGRAAAKGNNSLERERQNLPARPSRAPVSICGGGENTPKSAEEPVVRPKVRNVATPNCMKPKVFFDTDDDDDVPHSTSRWRDAADAEEAHAEGLARRGRGEAASSSEPRYAEDQDARSEQAKADKVPRRRRTMADPDFWAYTDDYYRYYEEDSDSDKEWMAALRRKYRSREQPQSSSGESWELLPGKEELERQQAGAGSLASAGSNGSGYPEEVQDPSLQEEEQASLEEGEIPWLRYNENESSSEGDNESTHELIQPGMFMLDGNNNLEDDSSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAVDVEVANPPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVSIWLQKSGTCPVCRCMFPPPL
|
Mus musculus
| null |
Not found
|
{}
| null |
{}
|
Slc6a4
|
METTPLNSQKVLSECKDKEDCQENGVLQKGVPTPADKAGPGQISNGYSAVPSTSAGDEAPHSTPAATTTLVAEIHQGERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWKKICPIFKGIGYAICIIAFYIASYYNTIIAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFAQDNITWTLHSTSPAEEFYLRHVLQIHQSKGLQDLGTISWQLALCIMLIFTIIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRGATLPGAWRGVVFYLKPNWQKLLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREWFVLIVVITCILGSLLTLTSGGAYVVTLLEEYATGPAVLTVALIEAVVVSWFYGITQFCSDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPHWSIILGYCIGTSSVICIPIYIIYRLISTPGTLKERIIKSITPETPTEIPCGDIRMNAV
|
Mus musculus
|
Cell membrane, Endomembrane system, Endosome membrane, Synapse, Cell junction, focal adhesion, Cell projection, neuron projection
|
Not found
|
{}
| null |
{}
|
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| null | null | null | null | null | null | null | null | null | null | null | 51.367664
| 0.820433
| 84.833492
| 0.333349
| 1,169
|
O55176
|
Q9QYH6
|
22199232
|
UbiNet, UbiBrowser
|
Pja1
|
MSHQERIASQRRTTAEVPMHRSTANQSKRSRSPFASTRRRWDDSESSGASLAVESEDYSRYPPREYRASGSRRGLAYGHIDTVVARDSEEEGAGPVDRLPVRGKAGKFKDDPEKGARSSRFTSVNHDAKEECGKVESPPAARCSARRAELSKQNGSSASQISSAEGRAAAKGNNSLERERQNLPARPSRAPVSICGGGENTPKSAEEPVVRPKVRNVATPNCMKPKVFFDTDDDDDVPHSTSRWRDAADAEEAHAEGLARRGRGEAASSSEPRYAEDQDARSEQAKADKVPRRRRTMADPDFWAYTDDYYRYYEEDSDSDKEWMAALRRKYRSREQPQSSSGESWELLPGKEELERQQAGAGSLASAGSNGSGYPEEVQDPSLQEEEQASLEEGEIPWLRYNENESSSEGDNESTHELIQPGMFMLDGNNNLEDDSSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALEERLAQAMETALAHLESLAVDVEVANPPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVSIWLQKSGTCPVCRCMFPPPL
|
Mus musculus
| null |
Not found
|
{}
| null |
{}
|
Maged1
|
MAQKPDGGAGLRGFQAEASVEDSALLVQTLMEAIQISEAPPTSQATAAASGPNASPQSSQPPTANEKADTEVSAAAARPKTGFKAQNATTKGPNDYSQARNAKEMPKNQSKAAFKSQNGTPKGPHAASDFSQAAPTGKSAKKSEMAFKGQNSTKAGPGTTYNFPQSPSANEMTNNQPKTAKAWNDTTKVPGADAQTQNVNQAKMADVGTSAGISEADGAAAQTSADGSQTQNVESRTIIRGKRTRKVNNLNVEENNSGDQRRASLASGNWRSAPVPVTTQQNPPGAPPNVVWQTPLAWQNPSGWQNQTARQTPPAARQSPPARQTPSAWQNPVAWQNPVIWPNPVIWQNPVIWPNPIVWPGPIVWPNPMAWQSTPGWQSPPSWQAPPSWQSPQDWQGPPDWQVPPDWSMPPDWSFPSDWPFPPDWIPADWPIPPDWQNLRPSPNLRSSSNSRASQNQGPPQPRDVALLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLKEIDKEEHLYILISTPESLAGILGTTKDTPKLGLLLVILGIIFMNGNRATEAVLWEALRKMGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVLRFIAEVQKRDPRDWTAQFMEAADEALDALDAAAAEAEARAEARNRMGIGDEAVSGPWSWDDIEFELLTWDEEGDFGDPWSRIPFTFWARYHQNARSRFPQAFTGPIIGPSGTATANFAANFGAIGFFWVE
|
Mus musculus
|
Nucleus, Cytoplasm, Cell membrane
|
Not found
|
{}
| null |
{}
|
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[1.0, 1.0, 1.0, 0.98, 1.0, 0.96, 1.0, 1.0, 1.0, 0.98, 0.94, 1.0, 1.0, 0.91, 0.87, 0.76, 0.74, 0.65, 0.68, 0.64, 0.67, 0.64, 0.52, 0.52, 0.58, 0.56, 0.47, 0.54, 0.61, 0.28, 0.26, 0.52, 0.22, 0.41, 0.75, 0.73, 0.46, 0.64, 0.72, 0.84, 0.87, 0.86, 0.76, 0.95, 0.76, 0.98, 0.91, 0.97, 0.98, 0.97, 0.98, 0.98, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 1.0, 0.91, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.91, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.91, 0.96, 0.95, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.94, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.94, 0.99, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.95, 0.96, 0.96, 0.97, 0.83, 0.98, 0.95, 0.98, 1.0, 1.0, 0.99, 1.0, 0.98, 0.99, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.93, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 0.99, 0.91, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.96, 1.0, 0.97, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 0.89, 0.78, 0.81, 0.82, 0.83, 0.9, 0.85, 0.79, 0.78, 0.93, 0.88, 0.91, 0.85, 0.86, 0.7, 0.9, 0.8, 0.74, 0.87, 0.76, 0.99, 0.94, 1.0, 0.95, 1.0, 1.0, 1.0, 0.98, 0.99, 0.97, 0.99, 1.0, 1.0, 0.98, 0.91, 0.97, 0.98, 0.98, 1.0, 1.0, 0.98, 0.98, 0.98, 0.96, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.89, 1.0, 0.9, 0.99, 0.97, 1.0, 0.97, 1.0, 0.98, 0.98, 0.98, 0.97, 0.98, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 0.99, 1.0, 0.97, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 0.99, 0.98, 0.99, 0.97, 0.98, 0.97, 0.99, 0.96, 1.0, 0.96, 1.0, 1.0, 1.0, 1.0, 0.98, 0.86, 0.79, 0.83, 0.88, 0.87, 0.92, 0.89, 0.95, 0.84, 0.99, 0.92, 0.99, 0.95, 0.92, 0.96, 0.94, 1.0, 1.0, 0.95, 0.86, 0.9, 0.89, 0.91, 0.88, 0.94, 0.84, 0.92, 0.89, 0.87, 0.94, 0.94, 0.94, 0.98, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.97, 0.94, 0.97, 0.95, 0.99, 0.96, 0.93, 1.0, 0.97, 0.95, 0.94, 0.93, 0.78, 0.89, 0.95, 0.94, 1.0, 0.97, 0.87, 0.97, 0.82, 0.96, 0.96, 0.9, 0.93, 0.92, 0.95, 0.83, 1.0, 0.75, 0.98, 0.96, 0.98, 0.99, 1.0, 0.92, 0.97, 0.91, 0.91, 0.97, 1.0, 0.91, 0.99, 0.91, 1.0, 1.0, 0.95, 0.98, 0.9, 0.92, 1.0, 0.97, 0.95, 0.89, 0.95, 0.89, 0.94, 1.0, 0.95, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.83, 0.98, 0.83, 0.96, 0.79, 0.95, 0.94, 0.91, 0.94, 0.63, 0.52, 0.34, 0.67, 0.29, 0.07, 0.11, 0.44, 0.16, 0.0, 0.18, 0.2, 0.0, 0.0, 0.07, 0.04, 0.0, 0.0, 0.14, 0.27, 0.07, 0.52, 0.37, 0.3, 0.28, 0.1, 0.04, 0.44, 0.3, 0.6, 0.25, 0.0, 0.25, 0.71, 0.28, 0.07, 0.0, 0.49, 0.78, 0.26, 0.55, 0.85, 0.24, 0.03, 0.45, 0.08, 0.0, 0.09, 0.12, 0.04, 0.0, 0.03, 0.1, 0.0, 0.0, 0.27, 0.54, 0.11, 0.0, 0.13, 0.06, 0.44, 0.05, 0.2, 0.32, 0.1, 0.18, 0.78, 0.93, 0.56, 0.36, 0.04, 0.06, 0.01, 0.06, 0.13, 0.3, 0.14, 0.7, 0.84, 0.25, 0.22, 0.75, 0.76, 0.26, 0.81, 0.33, 0.29, 0.38, 0.88, 0.7, 0.52, 0.45, 0.28, 0.33, 0.27, 0.07, 0.03, 0.18, 0.24, 0.0, 0.02, 0.04, 0.16, 0.0, 0.01, 0.33, 0.46, 0.71, 0.2, 0.52, 0.02, 0.36, 0.14, 0.65, 0.44, 0.01, 0.06, 0.45, 0.23, 0.02, 0.49, 0.47, 0.17, 0.59, 0.15, 0.68, 0.43, 0.72, 0.57, 0.82, 0.37, 0.97, 0.64, 0.11, 0.36, 0.37, 0.03, 0.48, 0.59, 0.01, 0.0, 0.3, 0.51, 0.33, 0.03, 0.27, 0.38, 0.1, 0.24, 0.09, 0.02, 0.29, 0.26, 0.52, 0.54, 0.26, 0.89, 0.95, 0.11, 0.94, 0.79, 0.57, 0.49, 0.37, 0.13, 0.01, 0.13, 0.07, 0.07, 0.35, 0.0, 0.01, 0.41, 0.33, 0.31, 0.16, 0.29, 0.07, 0.12, 0.48, 0.02, 0.0, 0.57, 0.38, 0.12, 0.03, 0.75, 0.22, 0.39, 0.79, 0.46, 0.42, 0.19, 0.64, 0.63, 0.16, 0.61, 0.7, 0.22, 0.25, 0.68, 0.35, 0.01, 0.35, 0.61, 0.21, 0.29, 0.58, 0.66, 0.53, 0.67, 0.64, 0.52, 0.43, 0.54, 0.53, 0.27, 0.56, 0.71, 0.51, 0.25, 0.44, 0.68, 0.25, 0.11, 0.74, 0.88, 0.3, 0.66, 0.09, 0.37, 0.56, 0.64, 0.08, 0.03, 0.55, 0.84, 0.92, 0.12, 0.32, 0.1, 0.85, 0.6, 0.17, 0.4, 0.7, 0.55, 0.12, 0.13, 0.62, 0.7, 0.4, 0.97, 0.63, 0.48, 0.55, 0.93, 0.4, 0.54, 0.22, 0.43, 0.56, 0.1, 0.07, 0.29, 0.74, 0.54, 0.06, 0.3, 0.34, 0.09, 0.25, 0.52, 0.63, 0.34, 0.39, 0.8, 0.72, 0.56, 0.81, 0.78, 0.92, 0.72, 0.96, 0.78, 0.8, 0.97, 0.96, 1.0, 0.98, 1.0, 0.99, 0.92, 1.0, 0.91, 0.99, 0.81, 0.98, 0.94, 0.84, 0.9, 0.96, 0.84, 0.88, 0.9, 0.75, 0.8, 0.87, 0.88, 0.85, 0.88, 0.85]
| null | null | null | null | null | null | null | null | null | null | null | 51.367664
| 0.820433
| 51.350297
| 0.727368
| 846
|
O60260
|
O00429
|
21292769, 23503661
|
UbiNet, UbiBrowser, 31181401, DegPred
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
|
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
|
{}
|
DNM1L
|
MEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTGIVTRRPLILQLVHVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKKSVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKTRINVLAAQYQSLLNSYGEPVDDKSATLLQLITKFATEYCNTIEGTAKYIETSELCGGARICYIFHETFGRTLESVDPLGGLNTIDILTAIRNATGPRPALFVPEVSFELLVKRQIKRLEEPSLRCVELVHEEMQRIIQHCSNYSTQELLRFPKLHDAIVEVVTCLLRKRLPVTNEMVHNLVAIELAYINTKHPDFADACGLMNNNIEEQRRNRLARELPSAVSRDKSSKVPSALAPASQEPSPAASAEADGKLIQDSRRETKNVASGGGGVGDGVQEPTTGNWRGMLKTSKAEELLAEEKSKPIPIMPASPQKGHAVNLLDVPVPVARKLSAREQRDCEVIERLIKSYFLIVRKNIQDSVPKAVMHFLVNHVKDTLQSELVGQLYKSSLLDDLLTESEDMAQRRKEAADMLKALQGASQIIAEIRETHLW
|
Homo sapiens
|
Cytoplasm, cytosol, Golgi apparatus, Endomembrane system, Mitochondrion outer membrane, Peroxisome, Membrane, clathrin-coated pit, Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
|
Low tissue specificity
|
{'Ciliated cells': '26.2', 'Basal respiratory cells': '27.2', 'Club cells': '28.6', 'Ionocytes': '21.7', 'Mucus glandular cells': '41.9', 'Serous glandular cells': '30.8', 'Gastric mucus-secreting cells': '30.1', 'Proximal enterocytes': '11.2', 'Paneth cells': '12.6', 'Distal enterocytes': '24.6', 'Intestinal goblet cells': '20.8', 'Exocrine glandular cells': '-0.591', 'Basal prostatic cells': '33.8', 'Prostatic glandular cells': '30.0', 'Breast glandular cells': '0.299', 'Breast myoepithelial cells': '0.337', 'Glandular and luminal cells': '51.7', 'Secretory cells': '37.1', 'Basal keratinocytes': '36.2', 'Suprabasal keratinocytes': '37.5', 'Basal squamous epithelial cells': '42.8', 'Squamous epithelial cells': '37.8', 'Alveolar cells type 1': '0.012', 'Alveolar cells type 2': '-0.239', 'Salivary duct cells': '51.9', 'Ductal cells': '0.685', 'Hepatocytes': '0.354', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.066', 'Distal tubular cells': '33.8', 'Collecting duct cells': '25.3', 'Mesothelial cells': '0.150', 'Sertoli cells': '0.095', 'Granulosa cells': '46.7', 'Enteroendocrine cells': '30.3', 'Pancreatic endocrine cells': '30.6', 'Leydig cells': '0.080', 'Excitatory neurons': '134.8', 'Inhibitory neurons': '143.7', 'Cone photoreceptor cells': '64.6', 'Rod photoreceptor cells': '168.8', 'Bipolar cells': '78.1', 'Horizontal cells': '106.4', 'Astrocytes': '78.3', 'Oligodendrocyte precursor cells': '93.4', 'Oligodendrocytes': '113.3', 'Microglial cells': '42.0', 'Muller glia cells': '54.9', 'Schwann cells': '0.291', 'Spermatogonia': '0.335', 'Spermatocytes': '0.599', 'Early spermatids': '0.412', 'Late spermatids': '-0.053', 'Oocytes': '77.9', 'Cytotrophoblasts': '30.2', 'Syncytiotrophoblasts': '31.0', 'Extravillous trophoblasts': '69.8', 'Endothelial cells': '39.2', 'Lymphatic endothelial cells': '52.0', 'Cardiomyocytes': '0.660', 'Skeletal myocytes': '0.098', 'Smooth muscle cells': '44.5', 'Adipocytes': '39.3', 'Melanocytes': '0.123', 'Fibroblasts': '39.9', 'Peritubular cells': '0.147', 'Endometrial stromal cells': '53.2', 'Ovarian stromal cells': '27.0', 'Undifferentiated cells': '27.5', 'T-cells': '40.7', 'B-cells': '34.1', 'Plasma cells': '36.3', 'Nk-cells': '53.8', 'Granulocytes': '34.0', 'Monocytes': '93.2', 'Macrophages': '45.1', 'Hofbauer cells': '29.5', 'Kupffer cells': '28.0', 'Dendritic cells': '44.7', 'Langerhans cells': '0.111', 'Erythroid cells': '-0.023', 'Adipocytes (Subcutaneous)': '-0.186', 'Adipocytes (Visceral)': '-0.208', 'Breast glandular cells (progenitors)': '0.128', 'Adipocytes (Breast)': '-0.282', 'Colon enterocytes': '-0.177', 'Colon enteroendocrine cells': '0.355', 'Enteric glia cells': '0.138', 'Mitotic cells (Colon)': '-0.042', 'Mitotic cells (Heart)': '0.507', 'Podocytes': '-0.066', 'Ascending Loop of Henle cells': '0.487', 'Intercalated cells': '0.022', 'Cholangiocyte': '0.405', 'NK-cells (Liver)': '-0.330', 'Respiratory ciliated cells': '0.014', 'Mitotic cells (Lung)': '0.038', 'NK-cells (Lung)': '0.270', 'B-cells (Lung)': '0.068', 'Alpha cells': '0.420', 'Beta cells': '0.287', 'Prostate glandular cells': '-0.193', 'Prostate basal glandular cells': '-0.043', 'Urothelial cells': '-0.098', 'Keratinocyte (other)': '0.011', 'Keratinocyte (granular)': '-0.389', 'Hair cortex cells': '0.105', 'Inner root sheath cells': '0.196', 'Outer root sheath cells': '0.344', 'Sebaceous gland cells': '0.140', 'Eccrine sweat gland cells': '0.202', 'Adipocytes (Skin)': '-0.027', 'Mitotic cells (Skin)': '0.325', 'Parietal cells': '-0.674', 'Chief cells': '-0.619', 'Gastric mucous cells': '-0.449', 'Gastric enteroendocrine cells': '-0.461', 'Mitotic cells (Stomach)': '-0.025', 'Parafollicular cells': '0.159', 'Thyroid glandular cells': '0.282', 'Mitotic cells (Thyroid)': '0.017', 'Adrenal cortex cells': '0.396', 'Adrenal medulla cells': '0.184', 'Mitotic cells (Adrenal gland)': '0.250', 'Minor salivary glandular cells': '0.264', 'Minor salivary gland ductal cells': '0.026', 'Minor salivary gland basal cells': '0.593', 'Mitotic cells (Minor salivary gland)': '0.587', 'Adipocytes (Minor salivary gland)': '0.224', 'Somatotropes': '-0.042', 'Lactotropes': '-0.008', 'Gonadotropes': '0.133', 'Corticotropes': '0.014', 'Thyrotropes': '0.218', 'Undifferentiated cells (Pituitary gland)': '0.170', 'Mitotic cells (Spleen)': '-0.183', 'Platelets': '-0.186', 'Erythrocytes': '-0.031', 'Hematopoietic stem cells': '-0.261', 'B-cells (Spleen)': '0.310', 'NK-cells (Spleen)': '0.329', 'Amygdala excitatory': '169.9', 'Cerebellar inhibitory': '221.6', 'Cge interneuron': '200.4', 'Deep-layer corticothalamic and 6b': '175.0', 'Deep-layer intratelencephalic': '174.4', 'Deep-layer near-projecting': '181.8', 'Eccentric medium spiny neuron': '189.1', 'Hippocampal ca1-3': '200.3', 'Hippocampal ca4': '171.7', 'Hippocampal dentate gyrus': '184.8', 'Lamp5-lhx6 and chandelier': '207.5', 'Lower rhombic lip': '165.1', 'Mammillary body': '227.4', 'Medium spiny neuron': '177.0', 'Mge interneuron': '199.4', 'Midbrain-derived inhibitory': '201.2', 'Miscellaneous': '177.2', 'Splatter': '183.5', 'Thalamic excitatory': '184.8', 'Upper rhombic lip': '193.0', 'Upper-layer intratelencephalic': '180.2', 'Astrocyte': '146.5', 'Bergmann glia': '152.2', 'Central nervous system macrophage': '116.6', 'Choroid plexus epithelial cell': '83.2', 'Committed oligodendrocyte precursor': '146.5', 'Ependymal cell': '111.3', 'Oligodendrocyte': '214.9', 'Oligodendrocyte precursor cell': '179.7', 'Endothelial cell': '114.3', 'Pericyte': '113.1', 'Vascular associated smooth muscle cell': '102.8', 'Fibroblast': '99.7', 'Leukocyte': '84.6', 'Basophil': '18.3', 'Eosinophil': '5.5', 'Neutrophil': '2.7', 'Classical monocyte': '51.5', 'Non-classical monocyte': '74.2', 'Intermediate monocyte': '48.7', 'T-reg': '18.1', 'GdT-cell': '6.6', 'MAIT T-cell': '20.8', 'Memory CD4 T-cell': '8.1', 'Naive CD4 T-cell': '69.5', 'Memory CD8 T-cell': '7.8', 'Naive CD8 T-cell': '64.0', 'Memory B-cell': '13.9', 'Naive B-cell': '65.6', 'Plasmacytoid DC': '46.4', 'Myeloid DC': '52.1', 'NK-cell': '56.1', 'Total PBMC': '27.7', 'Vd2 gdTCR': '22.0', 'Memory CD4 T-cell TFH': '48.9', 'Memory CD4 T-cell Th2': '60.6', 'Memory CD4 T-cell Th17': '56.6', 'Memory CD4 T-cell Th1\\/Th17': '68.7', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '54.9', 'Terminal effector memory CD4 T-cell': '30.1', 'Central memory CD8 T-cell': '25.6', 'Effector memory CD8 T-cell': '23.7', 'Terminal effector memory CD8 T-cell': '25.0', 'Switched memory B-cell': '29.2', 'Plasmablast': '42.5', 'Non-switched memory B-cell': '22.4', 'Exhausted memory B-cell': '22.2', 'Progenitor cell': '49.8', 'Naive CD4 T-cell activated': '62.3', 'Naive CD8 T-cell activated': '62.4', 'Memory T-reg': '42.2', 'Naive T-reg': '63.5'}
|
3W6N, 3W6O, 3W6P, 4BEJ, 4H1U, 4H1V, 5WP9, 8T1H
|
{'Adipose Tissue': 30.68006893687708, 'Adrenal Gland': 21.897391472868215, 'Bladder': 41.47238095238095, 'Blood': 15.546662002152852, 'Blood Vessel': 44.20830711610487, 'Brain': 46.88391294473883, 'Breast': 31.414596949891067, 'Cervix Uteri': 39.514736842105265, 'Colon': 34.08134788189987, 'Esophagus': 36.94629688581315, 'Fallopian Tube': 43.27777777777778, 'Heart': 18.88109988385598, 'Kidney': 18.81350561797753, 'Liver': 7.42787168141593, 'Lung': 33.22740484429065, 'Muscle': 22.868884184308843, 'Nerve': 39.190565428109856, 'Ovary': 39.17094444444445, 'Pancreas': 8.257204268292682, 'Pituitary': 46.74579505300353, 'Prostate': 38.706816326530614, 'Salivary Gland': 23.81376543209877, 'Skin': 32.036161967938085, 'Small Intestine': 26.473513368983955, 'Spleen': 26.34757676348547, 'Stomach': 23.19332033426184, 'Testis': 45.80387811634349, 'Thyroid': 36.12145482388974, 'Uterus': 48.38147887323944, 'Vagina': 35.588269230769235}
|
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90.68, 90.64, 87.63, 85.39, 87.19, 85.57, 84.17, 84.42, 85.44, 83.24, 83.3, 84.56, 85.05, 83.71, 84.32, 87.69, 86.28, 86.09, 88.63, 90.4, 87.66, 87.56, 89.3, 88.1, 85.33, 88.0, 85.97, 82.68, 81.16, 80.29, 76.09, 74.01, 68.74, 70.25, 67.55, 68.54, 70.47, 82.78, 83.1, 86.34, 87.27, 86.03, 89.37, 90.2, 89.26, 89.49, 91.37, 91.84, 90.08, 91.86, 92.92, 92.19, 90.4, 92.67, 93.38, 92.39, 90.61, 91.95, 91.65, 87.75, 86.98, 78.89, 76.55, 70.35, 74.67, 70.63, 79.86, 82.65, 85.65, 86.57, 86.55, 89.26, 92.24, 92.25, 93.44, 95.01, 94.46, 95.55, 95.5, 95.32, 92.31, 93.22, 92.82, 95.19, 91.65, 92.94, 92.73, 91.57, 91.59, 92.09, 90.88, 90.96, 87.24, 87.91, 85.01, 84.75, 86.12, 87.38, 85.94, 87.33, 88.94, 89.51, 89.02, 88.62, 88.71, 87.11, 88.09, 87.88, 87.3, 86.83, 85.83, 85.53, 78.08, 74.92, 69.17, 78.57, 82.34, 82.5, 85.93, 86.39, 88.87, 89.09, 90.58, 90.13, 90.2, 92.19, 93.03, 93.74, 92.8, 92.69, 93.79, 94.34, 94.42, 94.15, 94.99, 95.06, 95.07, 95.6, 96.5, 95.43, 96.3, 96.72, 96.31, 96.42, 96.51, 95.76, 95.28, 94.76, 94.7, 93.74, 91.75, 91.41, 89.19, 85.79, 84.96, 85.21, 80.09, 77.49, 68.59, 63.17, 68.32, 69.64, 74.55, 80.85, 77.76, 78.57, 87.66, 87.9, 90.2, 90.61, 90.15, 91.45, 91.74, 92.57, 92.35, 93.87, 94.11, 94.09, 94.52, 95.57, 95.09, 95.08, 95.28, 95.65, 94.75, 94.78, 96.32, 96.99, 96.32, 96.84, 97.37, 97.04, 95.96, 96.84, 96.73, 95.46, 94.43, 95.08, 94.78, 92.04, 92.51, 91.95, 91.18, 89.12, 86.9, 84.52, 83.03, 83.13, 83.7, 82.1, 83.71, 75.25, 72.87, 67.19, 66.13, 61.47, 57.9, 56.13, 54.94, 54.05, 52.54, 54.32, 56.1, 57.93, 56.85, 59.38, 60.44, 61.14, 57.63, 62.72, 60.89, 55.23, 45.69, 43.42, 44.66, 41.38, 36.62, 39.27, 28.32, 31.93, 26.06, 29.87, 26.86, 26.41, 27.19, 25.92, 31.26, 21.68, 23.88, 26.35, 22.72, 29.2, 24.49, 23.18, 24.83, 21.96, 27.6, 20.81, 28.5, 21.43, 24.73, 21.38, 23.42, 21.73, 25.55, 22.29, 22.03, 22.51, 25.68, 21.96, 19.51, 21.41, 23.88, 19.79, 23.47, 20.94, 19.04, 23.8, 20.53, 26.28, 20.08, 20.47, 20.31, 20.46, 18.8, 22.02, 20.57, 23.61, 18.97, 22.52, 22.53, 20.39, 22.95, 24.76, 21.42, 24.55, 27.83, 23.04, 22.81, 21.8, 23.01, 22.98, 21.91, 21.9, 20.45, 21.0, 22.1, 22.92, 21.91, 26.05, 23.08, 22.43, 25.25, 22.47, 23.45, 23.64, 25.02, 26.52, 27.06, 28.21, 31.3, 28.39, 31.23, 37.57, 32.03, 34.8, 39.43, 35.39, 36.68, 40.04, 49.39, 51.73, 52.63, 49.43, 53.0, 52.82, 45.98, 47.05, 43.82, 53.93, 44.18, 51.58, 46.73, 58.79, 61.74, 68.35, 78.89, 79.93, 81.17, 84.32, 85.68, 85.29, 86.96, 88.14, 88.36, 88.18, 88.68, 90.06, 87.63, 90.11, 91.57, 91.18, 89.31, 92.75, 93.35, 92.58, 92.02, 93.52, 94.32, 93.09, 93.42, 94.79, 94.15, 94.75, 95.77, 96.64, 96.71, 96.76, 96.65, 96.94, 96.05, 96.66, 96.36, 96.34, 95.96, 95.62, 95.88, 95.37, 94.31, 94.26, 94.74, 93.95, 93.36, 94.2, 93.56, 93.55, 93.1, 91.56, 89.74, 90.17, 89.19, 86.9, 78.76, 84.64, 85.41, 83.04, 82.65, 86.82, 86.65, 84.75, 82.41, 79.29, 80.92, 78.81, 78.24, 77.1, 77.42, 80.83, 82.02, 81.11, 83.08, 83.74, 83.53, 85.79, 85.34, 83.89, 86.57, 86.78, 84.58, 86.32, 87.38, 84.21, 83.39, 84.71, 84.65, 82.28, 79.55, 79.28, 73.91, 68.3, 56.83, 53.4, 49.23, 51.61, 48.8, 39.64]
|
[0.6, 0.7, 0.46, 0.05, 0.02, 0.43, 0.1, 0.06, 0.08, 0.44, 0.0, 0.09, 0.33, 0.28, 0.04, 0.35, 0.83, 0.29, 0.72, 0.16, 0.68, 0.46, 0.11, 0.46, 0.11, 0.07, 0.14, 0.0, 0.0, 0.01, 0.0, 0.01, 0.35, 0.4, 0.7, 0.02, 0.22, 0.08, 0.24, 0.15, 0.03, 0.02, 0.0, 0.12, 0.09, 0.03, 0.36, 0.48, 0.32, 0.0, 0.05, 0.11, 0.4, 0.66, 0.93, 0.28, 0.13, 0.3, 0.19, 0.1, 0.03, 0.0, 0.04, 0.06, 0.03, 0.03, 0.01, 0.23, 0.48, 0.1, 0.34, 0.79, 0.85, 0.4, 0.32, 0.86, 0.82, 0.54, 0.36, 0.64, 0.97, 0.85, 0.55, 0.88, 0.39, 0.97, 0.23, 0.63, 0.12, 0.1, 0.0, 0.34, 0.01, 0.57, 0.41, 0.24, 0.95, 0.46, 0.48, 0.36, 0.01, 0.43, 0.48, 0.11, 0.42, 0.42, 0.0, 0.25, 0.56, 0.2, 0.06, 0.43, 0.55, 0.06, 0.07, 0.47, 0.74, 0.42, 0.2, 0.34, 0.78, 0.68, 0.43, 0.16, 0.21, 0.13, 0.52, 0.5, 0.33, 0.05, 0.17, 0.01, 0.23, 0.0, 0.2, 0.01, 0.38, 0.77, 0.05, 0.38, 0.15, 0.01, 0.04, 0.0, 0.0, 0.01, 0.02, 0.02, 0.1, 0.14, 0.06, 0.7, 0.75, 0.42, 0.41, 0.78, 0.64, 0.11, 0.29, 0.9, 0.45, 0.01, 0.49, 0.65, 0.31, 0.01, 0.24, 0.7, 0.07, 0.01, 0.26, 0.62, 0.14, 0.0, 0.53, 0.08, 0.57, 0.24, 0.0, 0.04, 0.0, 0.01, 0.0, 0.01, 0.06, 0.12, 0.15, 0.52, 0.59, 0.6, 0.05, 0.63, 0.64, 0.11, 0.17, 0.01, 0.04, 0.53, 0.0, 0.02, 0.48, 0.49, 0.27, 0.1, 0.73, 0.54, 0.09, 0.66, 0.14, 0.03, 0.01, 0.01, 0.0, 0.02, 0.02, 0.29, 0.0, 0.45, 0.65, 0.16, 0.72, 0.96, 0.99, 0.44, 0.64, 0.02, 0.25, 0.42, 0.21, 0.11, 0.44, 0.24, 0.66, 0.52, 0.12, 0.78, 0.17, 0.73, 0.29, 0.31, 0.12, 0.03, 0.0, 0.0, 0.14, 0.17, 0.11, 0.4, 0.59, 0.66, 0.23, 0.19, 0.67, 0.69, 0.86, 0.26, 0.43, 0.06, 0.65, 0.39, 0.09, 0.21, 0.66, 0.47, 0.03, 0.5, 0.5, 0.28, 0.02, 0.56, 0.86, 0.47, 0.04, 0.63, 0.75, 0.14, 0.09, 0.73, 0.7, 0.11, 0.04, 0.06, 0.62, 0.32, 0.01, 0.13, 0.67, 0.07, 0.0, 0.16, 0.62, 0.21, 0.02, 0.21, 0.5, 0.19, 0.02, 0.37, 0.61, 0.16, 0.04, 0.47, 0.71, 0.12, 0.46, 0.58, 0.54, 0.01, 0.47, 0.48, 0.06, 0.18, 0.56, 0.54, 0.23, 0.38, 0.57, 0.38, 0.22, 0.61, 0.49, 0.21, 0.21, 0.83, 0.64, 0.29, 0.87, 0.51, 0.4, 0.28, 0.48, 0.22, 0.0, 0.38, 0.68, 0.09, 0.0, 0.34, 0.39, 0.0, 0.07, 0.47, 0.15, 0.0, 0.16, 0.22, 0.07, 0.12, 0.54, 0.62, 0.58, 0.17, 0.89, 0.64, 0.76, 0.29, 0.9, 0.8, 0.54, 0.49, 0.19, 0.0, 0.21, 0.45, 0.34, 0.04, 0.45, 0.41, 0.05, 0.09, 0.7, 0.41, 0.32, 0.02, 0.02, 0.63, 0.38, 0.0, 0.63, 0.73, 0.11, 0.51, 0.14, 0.13, 0.2, 0.69, 0.08, 0.61, 0.27, 0.52, 0.37, 0.0, 0.14, 0.44, 0.18, 0.09, 0.55, 0.72, 0.42, 0.19, 0.64, 0.96, 0.82, 0.91, 0.37, 0.85, 0.89, 0.33, 0.22, 0.78, 0.59, 0.01, 0.07, 0.41, 0.67, 0.04, 0.0, 0.29, 0.63, 0.02, 0.01, 0.6, 0.37, 0.0, 0.17, 0.76, 0.16, 0.0, 0.24, 0.45, 0.02, 0.0, 0.41, 0.26, 0.0, 0.1, 0.46, 0.05, 0.0, 0.31, 0.49, 0.0, 0.05, 0.64, 0.11, 0.0, 0.04, 0.63, 0.58, 0.2, 0.07, 0.58, 0.36, 0.01, 0.39, 0.1, 0.02, 0.38, 0.45, 0.0, 0.23, 0.63, 0.15, 0.0, 0.29, 0.72, 0.07, 0.0, 0.18, 0.53, 0.06, 0.0, 0.63, 0.66, 0.17, 0.23, 0.56, 0.38, 0.0, 0.27, 0.62, 0.29, 0.0, 0.5, 0.44, 0.16, 0.02, 0.37, 0.63, 0.19, 0.24, 0.71, 0.73, 0.14, 0.3, 0.53, 0.87, 0.24, 0.63, 0.53, 0.04, 0.47, 0.62, 0.22, 0.27, 0.4, 0.6, 0.19, 0.64, 0.61, 0.47, 0.36, 0.66, 0.56, 0.45, 0.57, 0.77, 0.61, 0.64, 0.64, 0.59, 0.88, 0.79, 0.79, 0.89, 0.88, 0.95, 0.94, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 0.99, 0.96, 0.98, 1.0, 1.0, 0.98, 0.98, 0.92, 0.95, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.93, 0.99, 0.94, 0.98, 0.99, 0.99, 1.0, 1.0, 0.99, 0.98, 0.99, 0.99, 0.99, 0.98, 0.99, 1.0, 1.0, 1.0, 1.0, 0.95, 0.99, 0.91, 0.99, 0.96, 1.0, 0.98, 0.99, 0.95, 0.99, 0.91, 0.98, 0.95, 0.99, 0.9, 1.0, 0.95, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.96, 1.0, 0.96, 1.0, 1.0, 0.99, 0.97, 0.98, 0.89, 0.84, 0.87, 0.89, 0.89, 0.77, 0.85, 0.76, 0.73, 0.6, 0.89, 0.78, 0.96, 0.36, 0.41, 0.68, 0.44, 0.23, 0.36, 0.56, 0.24, 0.0, 0.31, 0.39, 0.01, 0.2, 0.31, 0.21, 0.0, 0.42, 0.13, 0.03, 0.0, 0.38, 0.1, 0.01, 0.2, 0.66, 0.4, 0.02, 0.35, 0.51, 0.27, 0.0, 0.14, 0.58, 0.07, 0.0, 0.33, 0.73, 0.26, 0.0, 0.02, 0.35, 0.32, 0.0, 0.3, 0.79, 0.22, 0.01, 0.47, 0.61, 0.31, 0.0, 0.28, 0.58, 0.41, 0.05, 0.44, 0.47, 0.75, 0.85, 0.35, 0.14, 0.6, 0.49, 0.08, 0.11, 0.34, 0.31, 0.23, 0.82, 0.67, 0.26, 0.31, 0.52, 0.55, 0.25, 0.58, 0.53, 0.02, 0.37, 0.46, 0.11, 0.08, 0.73, 0.1, 0.01, 0.52, 0.26, 0.0, 0.32, 0.66, 0.12, 0.05, 0.63, 0.59, 0.09, 0.77, 0.65, 0.73, 0.36, 0.33, 0.8]
| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 76.550584
| 0.426957
| 932
|
O60260
|
O15354
|
12150907, 19218498, BioGrid E3NethUbiquitome
|
UbiNet, UbiBrowser, 31181401
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
|
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
|
{}
|
GPR37
|
MRAPGALLARMSRLLLLLLLKVSASSALGVAPASRNETCLGESCAPTVIQRRGRDAWGPGNSARDVLRARAPREEQGAAFLAGPSWDLPAAPGRDPAAGRGAEASAAGPPGPPTRPPGPWRWKGARGQEPSETLGRGNPTALQLFLQISEEEEKGPRGAGISGRSQEQSVKTVPGASDLFYWPRRAGKLQGSHHKPLSKTANGLAGHEGWTIALPGRALAQNGSLGEGIHEPGGPRRGNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYYMRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFTLCALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFSGRAPAERCIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFTITCSLVTARKIRKAEKACTRGNKRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLLNIISQFLLFFKSCVTPVLLFCLCKPFSRAFMECCCCCCEECIQKSSTVTSDDNDNEYTTELELSPFSTIRREMSTFASVGTHC
|
Homo sapiens
|
Cell projection, dendrite, Synapse, Cell membrane, Endoplasmic reticulum membrane
|
Group enriched (brain, retina)
|
{'Ciliated cells': '1.6', 'Basal respiratory cells': '4.5', 'Club cells': '2.2', 'Ionocytes': '5.2', 'Mucus glandular cells': '3.9', 'Serous glandular cells': '0.7', 'Gastric mucus-secreting cells': '0.6', 'Proximal enterocytes': '0.0', 'Paneth cells': '1.3', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '1.5', 'Exocrine glandular cells': '-0.537', 'Basal prostatic cells': '0.2', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.454', 'Breast myoepithelial cells': '0.349', 'Glandular and luminal cells': '3.5', 'Secretory cells': '3.3', 'Basal keratinocytes': '5.4', 'Suprabasal keratinocytes': '6.3', 'Basal squamous epithelial cells': '8.0', 'Squamous epithelial cells': '4.5', 'Alveolar cells type 1': '0.026', 'Alveolar cells type 2': '0.191', 'Salivary duct cells': '1.4', 'Ductal cells': '0.769', 'Hepatocytes': '0.653', 'Cholangiocytes': '9.5', 'Proximal tubular cells': '0.287', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.464', 'Sertoli cells': '0.840', 'Granulosa cells': '0.5', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.543', 'Excitatory neurons': '5.8', 'Inhibitory neurons': '1.0', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '12.8', 'Bipolar cells': '60.0', 'Horizontal cells': '13.8', 'Astrocytes': '5.6', 'Oligodendrocyte precursor cells': '1.4', 'Oligodendrocytes': '302.4', 'Microglial cells': '0.9', 'Muller glia cells': '595.5', 'Schwann cells': '0.146', 'Spermatogonia': '0.542', 'Spermatocytes': '0.248', 'Early spermatids': '-0.350', 'Late spermatids': '-0.540', 'Oocytes': '9.6', 'Cytotrophoblasts': '11.0', 'Syncytiotrophoblasts': '3.6', 'Extravillous trophoblasts': '23.3', 'Endothelial cells': '1.3', 'Lymphatic endothelial cells': '5.8', 'Cardiomyocytes': '0.180', 'Skeletal myocytes': '0.108', 'Smooth muscle cells': '0.9', 'Adipocytes': '0.2', 'Melanocytes': '0.206', 'Fibroblasts': '2.1', 'Peritubular cells': '0.305', 'Endometrial stromal cells': '0.5', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '0.4', 'T-cells': '0.2', 'B-cells': '0.0', 'Plasma cells': '0.5', 'Nk-cells': '0.0', 'Granulocytes': '1.6', 'Monocytes': '0.0', 'Macrophages': '0.4', 'Hofbauer cells': '0.5', 'Kupffer cells': '0.7', 'Dendritic cells': '0.0', 'Langerhans cells': '-0.019', 'Erythroid cells': '-0.093', 'Adipocytes (Subcutaneous)': '0.485', 'Adipocytes (Visceral)': '0.214', 'Breast glandular cells (progenitors)': '0.288', 'Adipocytes (Breast)': '-0.316', 'Colon enterocytes': '0.068', 'Colon enteroendocrine cells': '0.608', 'Enteric glia cells': '0.194', 'Mitotic cells (Colon)': '0.000', 'Mitotic cells (Heart)': '0.238', 'Podocytes': '0.079', 'Ascending Loop of Henle cells': '0.202', 'Intercalated cells': '0.108', 'Cholangiocyte': '0.165', 'NK-cells (Liver)': '-0.305', 'Respiratory ciliated cells': '0.055', 'Mitotic cells (Lung)': '0.080', 'NK-cells (Lung)': '-0.168', 'B-cells (Lung)': '-0.067', 'Alpha cells': '0.373', 'Beta cells': '0.231', 'Prostate glandular cells': '-0.148', 'Prostate basal glandular cells': '-0.080', 'Urothelial cells': '0.018', 'Keratinocyte (other)': '-0.137', 'Keratinocyte (granular)': '-0.224', 'Hair cortex cells': '0.294', 'Inner root sheath cells': '0.435', 'Outer root sheath cells': '0.319', 'Sebaceous gland cells': '0.120', 'Eccrine sweat gland cells': '0.265', 'Adipocytes (Skin)': '0.146', 'Mitotic cells (Skin)': '0.267', 'Parietal cells': '-0.584', 'Chief cells': '-0.415', 'Gastric mucous cells': '-0.602', 'Gastric enteroendocrine cells': '-0.352', 'Mitotic cells (Stomach)': '-0.258', 'Parafollicular cells': '0.022', 'Thyroid glandular cells': '0.034', 'Mitotic cells (Thyroid)': '0.106', 'Adrenal cortex cells': '0.117', 'Adrenal medulla cells': '0.161', 'Mitotic cells (Adrenal gland)': '0.076', 'Minor salivary glandular cells': '0.486', 'Minor salivary gland ductal cells': '0.022', 'Minor salivary gland basal cells': '0.055', 'Mitotic cells (Minor salivary gland)': '0.163', 'Adipocytes (Minor salivary gland)': '-0.120', 'Somatotropes': '-0.201', 'Lactotropes': '-0.161', 'Gonadotropes': '0.188', 'Corticotropes': '-0.098', 'Thyrotropes': '0.160', 'Undifferentiated cells (Pituitary gland)': '0.346', 'Mitotic cells (Spleen)': '-0.250', 'Platelets': '-0.126', 'Erythrocytes': '-0.026', 'Hematopoietic stem cells': '-0.213', 'B-cells (Spleen)': '0.070', 'NK-cells (Spleen)': '0.259', 'Amygdala excitatory': '10.0', 'Cerebellar inhibitory': '1.5', 'Cge interneuron': '1.4', 'Deep-layer corticothalamic and 6b': '18.1', 'Deep-layer intratelencephalic': '13.4', 'Deep-layer near-projecting': '15.8', 'Eccentric medium spiny neuron': '2.6', 'Hippocampal ca1-3': '16.4', 'Hippocampal ca4': '23.5', 'Hippocampal dentate gyrus': '16.4', 'Lamp5-lhx6 and chandelier': '1.0', 'Lower rhombic lip': '20.2', 'Mammillary body': '3.6', 'Medium spiny neuron': '3.8', 'Mge interneuron': '1.5', 'Midbrain-derived inhibitory': '6.4', 'Miscellaneous': '5.7', 'Splatter': '9.2', 'Thalamic excitatory': '2.4', 'Upper rhombic lip': '1.6', 'Upper-layer intratelencephalic': '6.2', 'Astrocyte': '16.6', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '7.0', 'Choroid plexus epithelial cell': '8.9', 'Committed oligodendrocyte precursor': '112.4', 'Ependymal cell': '14.4', 'Oligodendrocyte': '466.1', 'Oligodendrocyte precursor cell': '6.8', 'Endothelial cell': '4.6', 'Pericyte': '6.9', 'Vascular associated smooth muscle cell': '3.5', 'Fibroblast': '4.1', 'Leukocyte': '6.0', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
| null |
{'Adipose Tissue': 0.5437932973421927, 'Adrenal Gland': 0.1221185581395348, 'Bladder': 3.0675047619047615, 'Blood': 0.0274149720129171, 'Blood Vessel': 0.9902894232209738, 'Brain': 34.418661392884175, 'Breast': 1.1213176470588235, 'Cervix Uteri': 0.3718973684210526, 'Colon': 1.0900852374839538, 'Esophagus': 5.610276844290658, 'Fallopian Tube': 0.8098666666666667, 'Heart': 0.0700977293844367, 'Kidney': 0.5567230337078651, 'Liver': 7.799594247787611, 'Lung': 0.5950923356401384, 'Muscle': 0.562220199252802, 'Nerve': 0.4748018093699515, 'Ovary': 0.2255133888888889, 'Pancreas': 1.1841149085365852, 'Pituitary': 0.4737212720848056, 'Prostate': 1.0285234693877552, 'Salivary Gland': 1.579858024691358, 'Skin': 3.017746913764511, 'Small Intestine': 1.20248128342246, 'Spleen': 2.6632145228215767, 'Stomach': 2.2206658495821725, 'Testis': 27.357927977839335, 'Thyroid': 0.1568060949464012, 'Uterus': 2.6567323943661973, 'Vagina': 1.5002323717948718}
|
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[0.99, 0.96, 0.68, 0.47, 0.53, 0.5, 0.5, 0.16, 0.42, 0.73, 0.42, 0.38, 0.69, 0.57, 0.19, 0.46, 0.57, 0.43, 0.19, 0.55, 0.7, 0.46, 0.23, 0.33, 0.65, 0.21, 0.45, 0.72, 0.79, 0.68, 0.74, 0.94, 0.8, 0.83, 0.75, 0.89, 0.6, 0.91, 0.82, 0.94, 0.91, 1.0, 0.99, 1.0, 1.0, 0.96, 0.91, 0.92, 0.81, 0.93, 0.93, 0.95, 0.96, 0.98, 1.0, 1.0, 1.0, 0.98, 1.0, 0.97, 1.0, 0.99, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 1.0, 0.99, 0.97, 0.93, 0.97, 0.96, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.98, 0.95, 0.96, 0.93, 0.95, 0.98, 0.95, 0.98, 0.82, 0.94, 0.93, 0.89, 0.93, 0.88, 0.94, 0.93, 0.98, 0.93, 0.98, 0.85, 0.98, 0.78, 0.99, 0.96, 1.0, 0.98, 1.0, 0.94, 0.95, 1.0, 0.94, 0.78, 0.97, 0.94, 0.78, 0.94, 0.96, 0.91, 0.89, 0.99, 0.93, 1.0, 0.92, 1.0, 0.91, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.87, 0.97, 0.8, 0.93, 0.92, 0.86, 0.81, 0.84, 0.71, 0.9, 0.79, 0.79, 0.84, 0.78, 0.96, 0.9, 0.88, 0.87, 0.89, 0.94, 0.87, 0.91, 0.9, 1.0, 0.98, 1.0, 0.99, 0.98, 1.0, 0.99, 0.94, 0.99, 0.94, 0.97, 1.0, 0.97, 1.0, 0.99, 0.98, 0.83, 0.86, 0.89, 0.81, 0.83, 0.98, 0.94, 0.96, 0.99, 0.98, 0.9, 0.99, 0.92, 0.99, 0.97, 0.99, 0.93, 0.96, 0.95, 0.98, 1.0, 0.98, 1.0, 0.97, 0.98, 0.97, 1.0, 0.98, 1.0, 0.96, 0.84, 0.97, 0.76, 0.89, 0.94, 0.85, 0.82, 0.89, 0.84, 0.83, 0.66, 0.89, 0.52, 0.73, 0.75, 0.48, 0.45, 0.85, 0.74, 0.17, 0.6, 0.41, 0.3, 0.43, 0.54, 0.24, 0.4, 0.61, 0.44, 0.05, 0.64, 0.6, 0.04, 0.34, 0.33, 0.4, 0.0, 0.16, 0.63, 0.1, 0.0, 0.42, 0.16, 0.0, 0.16, 0.55, 0.07, 0.06, 0.43, 0.79, 0.36, 0.49, 0.59, 0.17, 0.34, 0.3, 0.12, 0.01, 0.09, 0.2, 0.03, 0.04, 0.15, 0.05, 0.03, 0.01, 0.13, 0.03, 0.0, 0.2, 0.11, 0.01, 0.0, 0.55, 0.56, 0.04, 0.05, 0.42, 0.24, 0.07, 0.09, 0.37, 0.25, 0.25, 0.48, 0.42, 0.6, 0.65, 0.18, 0.48, 0.67, 0.47, 0.47, 0.25, 0.04, 0.01, 0.15, 0.08, 0.08, 0.08, 0.09, 0.23, 0.19, 0.08, 0.0, 0.0, 0.04, 0.0, 0.0, 0.04, 0.01, 0.29, 0.01, 0.02, 0.17, 0.23, 0.03, 0.01, 0.46, 0.09, 0.03, 0.34, 0.44, 0.06, 0.14, 0.46, 0.48, 0.32, 0.88, 0.75, 0.19, 0.3, 0.78, 0.75, 0.56, 0.2, 0.73, 0.41, 0.69, 0.34, 0.15, 0.28, 0.47, 0.31, 0.17, 0.39, 0.7, 0.05, 0.03, 0.57, 0.27, 0.0, 0.13, 0.62, 0.28, 0.0, 0.47, 0.28, 0.01, 0.2, 0.37, 0.0, 0.22, 0.22, 0.15, 0.24, 0.47, 0.35, 0.78, 0.5, 0.81, 1.0, 0.61, 0.99, 0.82, 0.91, 0.57, 0.41, 0.25, 0.49, 0.43, 0.37, 0.41, 0.55, 0.17, 0.2, 0.78, 0.85, 0.3, 0.59, 0.72, 0.76, 0.45, 0.38, 0.57, 0.65, 0.07, 0.36, 0.55, 0.14, 0.35, 0.63, 0.42, 0.19, 0.24, 0.66, 0.39, 0.12, 0.4, 0.26, 0.25, 0.0, 0.21, 0.35, 0.68, 0.06, 0.13, 0.57, 0.43, 0.03, 0.51, 0.56, 0.13, 0.1, 0.53, 0.34, 0.0, 0.25, 0.71, 0.37, 0.1, 0.67, 0.76, 0.22, 0.55, 0.87, 0.78, 0.39, 0.83, 0.89, 0.74, 0.32, 0.56, 0.52, 0.16, 0.1, 0.54, 0.34, 0.09, 0.37, 0.2, 0.21, 0.07, 0.52, 0.02, 0.04, 0.35, 0.19, 0.05, 0.11, 0.63, 0.11, 0.04, 0.12, 0.61, 0.04, 0.04, 0.47, 0.3, 0.17, 0.1, 0.53, 0.07, 0.35, 0.4, 0.27, 0.3, 0.59, 0.64, 0.59, 0.51, 0.92, 0.88, 0.3, 0.51, 0.73, 0.74, 0.42, 0.14, 0.57, 0.55, 0.25, 0.39, 0.24, 0.44, 0.12, 0.22, 0.13, 0.15, 0.08, 0.01, 0.37, 0.05, 0.0, 0.09, 0.26, 0.02, 0.01, 0.48, 0.22, 0.0, 0.16, 0.75, 0.36, 0.08, 0.65, 0.4, 0.01, 0.36, 0.6, 0.13, 0.3, 0.58, 0.58, 0.54, 0.35, 0.34, 0.73, 0.8, 0.48, 0.82, 0.83, 0.45, 0.68, 0.74, 0.81, 0.54, 0.71, 0.81, 0.87, 0.5, 0.92, 0.95, 0.87, 0.5, 0.66, 0.72, 0.63, 0.73, 0.54, 0.44, 0.37, 0.69, 0.49, 0.62, 0.42, 0.32, 0.37, 0.22, 0.74, 0.35, 0.49, 0.88, 0.87, 0.64, 0.67, 0.86, 0.9, 0.85, 0.99, 0.8, 0.93, 0.9, 0.98, 0.9]
| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 61.407651
| 0.589902
| 1,222
|
O60260
|
O43175
|
32478681
|
UbiNet, UbiBrowser
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
|
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
|
{}
|
PHGDH
|
MAFANLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQGTSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSPAAPGEQGFGECLLAVALAGAPYQAVGLVQGTTPVLQGLNGAVFRPEVPLRRDLPLLLFRTQTSDPAMLPTMIGLLAEAGVRLLSYQTSLVSDGETWHVMGISSLLPSLEAWKQHVTEAFQFHF
|
Homo sapiens
| null |
Low tissue specificity
|
{'Ciliated cells': '31.2', 'Basal respiratory cells': '28.8', 'Club cells': '21.3', 'Ionocytes': '15.1', 'Mucus glandular cells': '54.1', 'Serous glandular cells': '214.6', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '0.4', 'Paneth cells': '3.4', 'Distal enterocytes': '1.3', 'Intestinal goblet cells': '2.2', 'Exocrine glandular cells': '-0.182', 'Basal prostatic cells': '30.9', 'Prostatic glandular cells': '159.9', 'Breast glandular cells': '0.325', 'Breast myoepithelial cells': '0.520', 'Glandular and luminal cells': '11.7', 'Secretory cells': '90.5', 'Basal keratinocytes': '70.8', 'Suprabasal keratinocytes': '74.1', 'Basal squamous epithelial cells': '47.2', 'Squamous epithelial cells': '54.1', 'Alveolar cells type 1': '-0.174', 'Alveolar cells type 2': '0.297', 'Salivary duct cells': '28.2', 'Ductal cells': '0.032', 'Hepatocytes': '0.715', 'Cholangiocytes': '124.0', 'Proximal tubular cells': '0.194', 'Distal tubular cells': '64.5', 'Collecting duct cells': '25.3', 'Mesothelial cells': '0.566', 'Sertoli cells': '-0.372', 'Granulosa cells': '46.9', 'Enteroendocrine cells': '2.0', 'Pancreatic endocrine cells': '71.3', 'Leydig cells': '-0.402', 'Excitatory neurons': '0.3', 'Inhibitory neurons': '0.5', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '2.2', 'Bipolar cells': '0.4', 'Horizontal cells': '1.9', 'Astrocytes': '30.0', 'Oligodendrocyte precursor cells': '13.2', 'Oligodendrocytes': '30.1', 'Microglial cells': '2.7', 'Muller glia cells': '71.7', 'Schwann cells': '0.188', 'Spermatogonia': '-0.227', 'Spermatocytes': '-0.110', 'Early spermatids': '0.512', 'Late spermatids': '0.404', 'Oocytes': '0.7', 'Cytotrophoblasts': '60.9', 'Syncytiotrophoblasts': '23.8', 'Extravillous trophoblasts': '45.5', 'Endothelial cells': '9.3', 'Lymphatic endothelial cells': '8.9', 'Cardiomyocytes': '0.117', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '33.3', 'Adipocytes': '3.9', 'Melanocytes': '0.418', 'Fibroblasts': '65.2', 'Peritubular cells': '-0.143', 'Endometrial stromal cells': '3.3', 'Ovarian stromal cells': '82.6', 'Undifferentiated cells': '11.2', 'T-cells': '4.8', 'B-cells': '5.5', 'Plasma cells': '48.3', 'Nk-cells': '0.8', 'Granulocytes': '3.3', 'Monocytes': '0.0', 'Macrophages': '5.5', 'Hofbauer cells': '5.5', 'Kupffer cells': '3.9', 'Dendritic cells': '1.8', 'Langerhans cells': '0.283', 'Erythroid cells': '0.031', 'Adipocytes (Subcutaneous)': '-0.265', 'Adipocytes (Visceral)': '0.025', 'Breast glandular cells (progenitors)': '0.419', 'Adipocytes (Breast)': '-0.390', 'Colon enterocytes': '-0.061', 'Colon enteroendocrine cells': '0.325', 'Enteric glia cells': '0.158', 'Mitotic cells (Colon)': '-0.109', 'Mitotic cells (Heart)': '0.312', 'Podocytes': '-0.032', 'Ascending Loop of Henle cells': '0.503', 'Intercalated cells': '0.181', 'Cholangiocyte': '0.041', 'NK-cells (Liver)': '0.202', 'Respiratory ciliated cells': '-0.022', 'Mitotic cells (Lung)': '0.277', 'NK-cells (Lung)': '-0.252', 'B-cells (Lung)': '-0.176', 'Alpha cells': '0.153', 'Beta cells': '-0.018', 'Prostate glandular cells': '0.623', 'Prostate basal glandular cells': '0.325', 'Urothelial cells': '-0.122', 'Keratinocyte (other)': '0.415', 'Keratinocyte (granular)': '-0.290', 'Hair cortex cells': '0.253', 'Inner root sheath cells': '0.239', 'Outer root sheath cells': '0.452', 'Sebaceous gland cells': '0.025', 'Eccrine sweat gland cells': '-0.061', 'Adipocytes (Skin)': '-0.237', 'Mitotic cells (Skin)': '0.547', 'Parietal cells': '-0.328', 'Chief cells': '-0.006', 'Gastric mucous cells': '-0.205', 'Gastric enteroendocrine cells': '-0.111', 'Mitotic cells (Stomach)': '0.021', 'Parafollicular cells': '0.062', 'Thyroid glandular cells': '0.327', 'Mitotic cells (Thyroid)': '0.039', 'Adrenal cortex cells': '0.064', 'Adrenal medulla cells': '0.103', 'Mitotic cells (Adrenal gland)': '0.225', 'Minor salivary glandular cells': '0.696', 'Minor salivary gland ductal cells': '0.269', 'Minor salivary gland basal cells': '-0.460', 'Mitotic cells (Minor salivary gland)': '-0.452', 'Adipocytes (Minor salivary gland)': '-0.341', 'Somatotropes': '-0.129', 'Lactotropes': '0.098', 'Gonadotropes': '0.277', 'Corticotropes': '-0.149', 'Thyrotropes': '0.148', 'Undifferentiated cells (Pituitary gland)': '0.467', 'Mitotic cells (Spleen)': '0.512', 'Platelets': '0.144', 'Erythrocytes': '0.170', 'Hematopoietic stem cells': '0.173', 'B-cells (Spleen)': '-0.244', 'NK-cells (Spleen)': '-0.339', 'Amygdala excitatory': '1.6', 'Cerebellar inhibitory': '3.3', 'Cge interneuron': '1.8', 'Deep-layer corticothalamic and 6b': '1.4', 'Deep-layer intratelencephalic': '1.5', 'Deep-layer near-projecting': '0.9', 'Eccentric medium spiny neuron': '4.5', 'Hippocampal ca1-3': '1.2', 'Hippocampal ca4': '1.7', 'Hippocampal dentate gyrus': '4.1', 'Lamp5-lhx6 and chandelier': '1.1', 'Lower rhombic lip': '1.1', 'Mammillary body': '1.1', 'Medium spiny neuron': '3.1', 'Mge interneuron': '1.4', 'Midbrain-derived inhibitory': '0.9', 'Miscellaneous': '2.5', 'Splatter': '2.3', 'Thalamic excitatory': '1.3', 'Upper rhombic lip': '2.4', 'Upper-layer intratelencephalic': '1.5', 'Astrocyte': '54.4', 'Bergmann glia': '61.5', 'Central nervous system macrophage': '3.4', 'Choroid plexus epithelial cell': '15.0', 'Committed oligodendrocyte precursor': '23.7', 'Ependymal cell': '40.5', 'Oligodendrocyte': '56.7', 'Oligodendrocyte precursor cell': '31.9', 'Endothelial cell': '2.3', 'Pericyte': '6.2', 'Vascular associated smooth muscle cell': '11.1', 'Fibroblast': '17.8', 'Leukocyte': '4.9', 'Basophil': '8.4', 'Eosinophil': '0.2', 'Neutrophil': '4.4', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '1.9', 'T-reg': '4.0', 'GdT-cell': '4.7', 'MAIT T-cell': '1.8', 'Memory CD4 T-cell': '2.4', 'Naive CD4 T-cell': '3.2', 'Memory CD8 T-cell': '8.2', 'Naive CD8 T-cell': '8.8', 'Memory B-cell': '11.1', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '2.3', 'Myeloid DC': '5.7', 'NK-cell': '0.7', 'Total PBMC': '7.8', 'Vd2 gdTCR': '5.3', 'Memory CD4 T-cell Th1\\/Th17': '0.2', 'Memory CD4 T-cell Th17': '0.6', 'Memory CD4 T-cell Th2': '1.2', 'Non-Vd2 gdTCR': '2.6', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '1.3', 'Terminal effector memory CD4 T-cell': '2.3', 'Central memory CD8 T-cell': '12.2', 'Effector memory CD8 T-cell': '8.7', 'Terminal effector memory CD8 T-cell': '3.2', 'Non-switched memory B-cell': '5.3', 'Plasmablast': '74.7', 'Switched memory B-cell': '15.8', 'Exhausted memory B-cell': '8.6', 'Progenitor cell': '52.4', 'Memory T-reg': '0.9', 'Naive CD4 T-cell activated': '4.0', 'Naive CD8 T-cell activated': '11.8', 'Naive T-reg': '0.7'}
|
2G76, 5N53, 5N6C, 5NZO, 5NZP, 5NZQ, 5OFM, 5OFV, 5OFW, 6CWA, 6PLF, 6PLG, 6RIH, 6RJ2, 6RJ3, 6RJ5, 6RJ6, 7CVP, 7DKM, 7EWH, 7VA1
|
{'Adipose Tissue': 17.480663704318935, 'Adrenal Gland': 1.5590251937984496, 'Bladder': 24.976666666666667, 'Blood': 5.389271324004306, 'Blood Vessel': 36.24477153558052, 'Brain': 35.42728122634367, 'Breast': 17.293442265795207, 'Cervix Uteri': 28.20105263157895, 'Colon': 14.307900770218229, 'Esophagus': 20.6273660899654, 'Fallopian Tube': 32.71222222222222, 'Heart': 4.8615868757259, 'Kidney': 13.880584269662922, 'Liver': 28.097933628318582, 'Lung': 13.740005190311418, 'Muscle': 0.7814231880448318, 'Nerve': 25.636434571890145, 'Ovary': 35.472055555555556, 'Pancreas': 21.488301829268295, 'Pituitary': 16.74356890459364, 'Prostate': 37.76323265306122, 'Salivary Gland': 48.24878395061728, 'Skin': 60.24324765063571, 'Small Intestine': 8.437998930481283, 'Spleen': 3.8668008298755185, 'Stomach': 19.71241504178273, 'Testis': 46.08470083102493, 'Thyroid': 20.372471516079635, 'Uterus': 25.14007746478873, 'Vagina': 43.9526282051282}
|
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| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 92.700957
| 0.306304
| 1,468
|
O60260
|
O43236
|
22792159
|
UbiNet, UbiBrowser
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
|
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
|
{}
|
SEPTIN4
|
MDRSLGWQGNSVPEDRTEAGIKRFLEDTTDDGELSKFVKDFSGNASCHPPEAKTWASRPQVPEPRPQAPDLYDDDLEFRPPSRPQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVPPGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
|
Homo sapiens
|
Cytoplasm, Cell projection, cilium, flagellum, Cytoplasmic vesicle, secretory vesicle, Cell projection, axon, Cell projection, dendrite, Perikaryon, Synapse, Mitochondrion, Nucleus
|
Group enriched (brain, retina)
|
{'Ciliated cells': '0.6', 'Basal respiratory cells': '0.8', 'Club cells': '0.2', 'Ionocytes': '0.7', 'Mucus glandular cells': '1.2', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.2', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.237', 'Basal prostatic cells': '0.9', 'Prostatic glandular cells': '1.8', 'Breast glandular cells': '0.091', 'Breast myoepithelial cells': '0.045', 'Glandular and luminal cells': '5.4', 'Secretory cells': '0.4', 'Basal keratinocytes': '3.8', 'Suprabasal keratinocytes': '3.0', 'Basal squamous epithelial cells': '0.4', 'Squamous epithelial cells': '1.1', 'Alveolar cells type 1': '0.226', 'Alveolar cells type 2': '-0.558', 'Salivary duct cells': '0.7', 'Ductal cells': '0.408', 'Hepatocytes': '0.566', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.043', 'Distal tubular cells': '18.4', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.098', 'Sertoli cells': '-0.580', 'Granulosa cells': '10.0', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.566', 'Excitatory neurons': '14.8', 'Inhibitory neurons': '27.6', 'Cone photoreceptor cells': '570.9', 'Rod photoreceptor cells': '318.4', 'Bipolar cells': '164.1', 'Horizontal cells': '560.9', 'Astrocytes': '28.8', 'Oligodendrocyte precursor cells': '3.8', 'Oligodendrocytes': '152.2', 'Microglial cells': '7.2', 'Muller glia cells': '90.1', 'Schwann cells': '0.036', 'Spermatogonia': '-0.393', 'Spermatocytes': '-0.063', 'Early spermatids': '0.668', 'Late spermatids': '0.755', 'Oocytes': '1.5', 'Cytotrophoblasts': '5.9', 'Syncytiotrophoblasts': '5.5', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '10.3', 'Lymphatic endothelial cells': '0.2', 'Cardiomyocytes': '0.650', 'Skeletal myocytes': '0.027', 'Smooth muscle cells': '91.5', 'Adipocytes': '33.5', 'Melanocytes': '-0.080', 'Fibroblasts': '11.7', 'Peritubular cells': '-0.398', 'Endometrial stromal cells': '1.1', 'Ovarian stromal cells': '11.6', 'Undifferentiated cells': '0.6', 'T-cells': '1.3', 'B-cells': '0.7', 'Plasma cells': '1.5', 'Nk-cells': '0.4', 'Granulocytes': '2.5', 'Monocytes': '0.0', 'Macrophages': '2.6', 'Hofbauer cells': '4.4', 'Kupffer cells': '2.4', 'Dendritic cells': '0.0', 'Langerhans cells': '-0.087', 'Erythroid cells': '0.077', 'Adipocytes (Subcutaneous)': '-0.138', 'Adipocytes (Visceral)': '-0.145', 'Breast glandular cells (progenitors)': '-0.089', 'Adipocytes (Breast)': '0.103', 'Colon enterocytes': '-0.187', 'Colon enteroendocrine cells': '0.300', 'Enteric glia cells': '0.656', 'Mitotic cells (Colon)': '-0.170', 'Mitotic cells (Heart)': '0.424', 'Podocytes': '0.128', 'Ascending Loop of Henle cells': '0.378', 'Intercalated cells': '0.198', 'Cholangiocyte': '0.134', 'NK-cells (Liver)': '0.162', 'Respiratory ciliated cells': '0.055', 'Mitotic cells (Lung)': '-0.261', 'NK-cells (Lung)': '0.415', 'B-cells (Lung)': '0.166', 'Alpha cells': '0.421', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.564', 'Prostate basal glandular cells': '-0.295', 'Urothelial cells': '-0.027', 'Keratinocyte (other)': '-0.490', 'Keratinocyte (granular)': '-0.366', 'Hair cortex cells': '0.375', 'Inner root sheath cells': '0.376', 'Outer root sheath cells': '0.529', 'Sebaceous gland cells': '0.076', 'Eccrine sweat gland cells': '0.531', 'Adipocytes (Skin)': '0.437', 'Mitotic cells (Skin)': '0.100', 'Parietal cells': '-0.655', 'Chief cells': '-0.562', 'Gastric mucous cells': '-0.611', 'Gastric enteroendocrine cells': '-0.396', 'Mitotic cells (Stomach)': '-0.210', 'Parafollicular cells': '-0.020', 'Thyroid glandular cells': '0.107', 'Mitotic cells (Thyroid)': '0.047', 'Adrenal cortex cells': '0.271', 'Adrenal medulla cells': '-0.038', 'Mitotic cells (Adrenal gland)': '-0.036', 'Minor salivary glandular cells': '0.075', 'Minor salivary gland ductal cells': '0.269', 'Minor salivary gland basal cells': '0.073', 'Mitotic cells (Minor salivary gland)': '0.030', 'Adipocytes (Minor salivary gland)': '0.360', 'Somatotropes': '-0.377', 'Lactotropes': '-0.373', 'Gonadotropes': '-0.081', 'Corticotropes': '-0.260', 'Thyrotropes': '-0.053', 'Undifferentiated cells (Pituitary gland)': '0.636', 'Mitotic cells (Spleen)': '-0.265', 'Platelets': '-0.157', 'Erythrocytes': '0.021', 'Hematopoietic stem cells': '-0.185', 'B-cells (Spleen)': '0.072', 'NK-cells (Spleen)': '0.183', 'Amygdala excitatory': '12.2', 'Cerebellar inhibitory': '51.7', 'Cge interneuron': '31.2', 'Deep-layer corticothalamic and 6b': '17.9', 'Deep-layer intratelencephalic': '10.8', 'Deep-layer near-projecting': '30.2', 'Eccentric medium spiny neuron': '6.3', 'Hippocampal ca1-3': '32.0', 'Hippocampal ca4': '15.9', 'Hippocampal dentate gyrus': '5.7', 'Lamp5-lhx6 and chandelier': '47.0', 'Lower rhombic lip': '102.9', 'Mammillary body': '26.9', 'Medium spiny neuron': '4.0', 'Mge interneuron': '44.5', 'Midbrain-derived inhibitory': '19.5', 'Miscellaneous': '30.5', 'Splatter': '31.1', 'Thalamic excitatory': '61.6', 'Upper rhombic lip': '60.6', 'Upper-layer intratelencephalic': '8.3', 'Astrocyte': '52.4', 'Bergmann glia': '991.8', 'Central nervous system macrophage': '13.7', 'Choroid plexus epithelial cell': '14.0', 'Committed oligodendrocyte precursor': '99.6', 'Ependymal cell': '9.4', 'Oligodendrocyte': '296.5', 'Oligodendrocyte precursor cell': '17.7', 'Endothelial cell': '15.4', 'Pericyte': '109.1', 'Vascular associated smooth muscle cell': '67.4', 'Fibroblast': '53.7', 'Leukocyte': '12.1', 'Basophil': '0.0', 'Eosinophil': '0.8', 'Neutrophil': '9.7', 'Classical monocyte': '0.9', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.5', 'T-reg': '1.5', 'GdT-cell': '4.9', 'MAIT T-cell': '4.5', 'Memory CD4 T-cell': '1.0', 'Naive CD4 T-cell': '0.3', 'Memory CD8 T-cell': '1.3', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '1.6', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '1.2', 'Myeloid DC': '1.8', 'NK-cell': '1.2', 'Total PBMC': '5.5', 'Vd2 gdTCR': '6.2', 'Memory CD4 T-cell Th1\\/Th17': '0.5', 'Memory CD4 T-cell Th17': '0.4', 'Memory CD4 T-cell Th2': '0.3', 'Non-Vd2 gdTCR': '4.8', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.4', 'Terminal effector memory CD4 T-cell': '7.9', 'Central memory CD8 T-cell': '1.0', 'Effector memory CD8 T-cell': '0.9', 'Terminal effector memory CD8 T-cell': '4.8', 'Non-switched memory B-cell': '1.5', 'Plasmablast': '0.1', 'Switched memory B-cell': '4.2', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '0.5', 'Memory T-reg': '0.4', 'Naive CD4 T-cell activated': '0.1', 'Naive CD8 T-cell activated': '0.1', 'Naive T-reg': '0.4'}
|
6WB3
|
{}
|
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|
[0.3, 0.19, 0.02, 0.02, 0.0, 0.08, 0.07, 0.12, 0.1, 0.29, 0.13, 0.0, 0.08, 0.4, 0.08, 0.86, 0.06, 0.64, 0.51, 0.76, 0.17, 0.23, 0.0, 0.42, 0.46, 0.04, 0.05, 0.38, 0.51, 0.01, 0.11, 0.81, 0.61, 0.34, 0.79, 0.2, 0.5, 0.2, 0.8, 0.29, 0.02, 0.07, 0.0, 0.01, 0.15, 0.37, 0.23, 0.67, 0.42, 0.05, 0.57, 0.41, 0.67, 0.4, 0.24, 0.03, 0.72, 0.65, 0.11, 0.71, 0.08, 0.66, 0.59, 0.49, 0.11, 0.22, 0.01, 0.08, 0.0, 0.01, 0.37, 0.2, 0.55, 0.58, 0.7, 0.7, 0.84, 0.57, 0.73, 0.81, 0.94, 0.84, 0.96, 0.99, 0.81, 0.96, 0.91, 0.93, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.85, 1.0, 0.81, 1.0, 0.98, 1.0, 1.0, 0.92, 0.96, 0.94, 0.94, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 0.97, 0.92, 0.92, 0.75, 0.78, 0.77, 0.81, 0.93, 0.83, 0.96, 0.85, 0.98, 0.87, 0.9, 0.95, 0.92, 0.95, 0.89, 0.92, 0.71, 0.94, 0.91, 0.74, 0.82, 0.75, 0.29, 0.14, 0.04, 0.0, 0.11, 0.0, 0.06, 0.01, 0.58, 0.68, 0.79, 0.26, 0.47, 0.55, 0.25, 0.12, 0.33, 0.01, 0.29, 0.0, 0.29, 0.17, 0.19, 0.0, 0.34, 0.62, 0.34, 0.7, 0.44, 0.77, 0.3, 0.1, 0.56, 0.2, 0.72, 0.7, 0.29, 0.0, 0.35, 0.39, 0.12, 0.55, 0.1, 0.09, 0.46, 0.53, 0.91, 0.61, 0.66, 0.06, 0.52, 0.15, 0.67, 0.09, 0.58, 0.2, 0.92, 0.94, 0.2, 0.75, 0.03, 0.58, 0.27, 0.07, 0.36, 0.13, 0.14, 0.05, 0.08, 0.01, 0.27, 0.61, 0.25, 0.98, 0.26, 0.48, 0.67, 0.89, 0.48, 0.65, 0.17, 0.33, 0.13, 0.0, 0.25, 0.06, 0.0, 0.07, 0.24, 0.07, 0.57, 0.29, 0.62, 0.08, 0.21, 0.03, 0.02, 0.38, 0.34, 0.49, 0.4, 0.52, 0.22, 0.35, 0.18, 0.03, 0.0, 0.11, 0.01, 0.36, 0.01, 0.91, 0.29, 0.35, 0.05, 0.0, 0.0, 0.04, 0.15, 0.22, 0.12, 0.0, 0.06, 0.1, 0.06, 0.0, 0.0, 0.06, 0.12, 0.05, 0.0, 0.23, 0.21, 0.37, 0.08, 0.41, 0.59, 0.35, 0.85, 0.96, 0.29, 0.3, 0.17, 0.0, 0.01, 0.25, 0.01, 0.06, 0.39, 0.69, 0.21, 0.89, 0.89, 0.02, 0.23, 0.02, 0.66, 0.33, 0.25, 0.35, 0.0, 0.0, 0.22, 0.15, 0.08, 0.26, 0.49, 0.63, 0.07, 0.1, 0.55, 0.22, 0.1, 0.6, 0.58, 0.02, 0.34, 0.5, 0.15, 0.19, 0.41, 0.17, 0.36, 0.74, 0.62, 0.43, 0.18, 0.07, 0.12, 0.04, 0.09, 0.48, 0.45, 0.84, 0.29, 0.3, 0.3, 0.5, 0.1, 0.62, 0.25, 0.79, 0.77, 0.95, 0.45, 0.33, 0.46, 0.03, 0.36, 0.02, 0.78, 0.39, 0.94, 0.86, 0.76, 0.8, 0.31, 0.26, 0.61, 0.25, 0.31, 0.0, 0.0, 0.26, 0.69, 0.1, 0.33, 0.4, 0.53, 0.34, 0.3, 0.81, 0.61, 0.91, 0.29, 0.58, 0.75, 0.28, 0.48, 0.19, 0.6, 0.79, 0.73, 0.43, 0.82, 0.53, 0.59, 0.64, 0.21, 0.83, 0.24, 0.61, 0.77, 0.74, 0.06, 0.14, 0.6, 0.56, 0.0, 0.4, 0.08, 0.56, 0.62, 0.3, 0.5, 0.86, 0.92, 0.48, 0.7, 0.74, 0.73, 0.51, 0.52, 0.31, 0.61, 0.0, 0.37, 0.59, 0.36, 0.65, 0.32, 0.69, 0.07, 0.6, 0.25, 0.76, 0.64, 0.19, 0.13, 0.03, 0.35, 0.08, 0.61, 0.05, 0.67, 0.47, 0.64, 0.99, 0.12, 0.63, 0.08, 0.36, 0.02, 0.0, 0.08, 0.5, 0.34, 0.38, 0.36, 0.68, 0.18, 0.4, 0.75, 0.63, 0.04, 0.25, 0.01, 0.14, 0.06, 0.05, 0.01, 0.45, 0.31]
|
[35.52, 34.38, 32.87, 28.97, 35.84, 28.32, 22.43, 28.37, 22.84, 26.45, 26.29, 22.98, 23.92, 23.35, 26.8, 23.4, 27.1, 23.83, 25.95, 26.82, 25.42, 25.55, 27.64, 25.69, 26.25, 27.96, 33.39, 31.38, 39.46, 39.16, 42.87, 39.53, 42.0, 43.36, 45.41, 44.1, 41.53, 46.99, 41.33, 40.56, 32.31, 31.07, 29.41, 23.32, 27.44, 21.59, 17.16, 22.9, 28.74, 28.14, 20.63, 19.25, 27.04, 20.41, 18.26, 21.85, 24.98, 23.14, 33.65, 25.83, 25.55, 36.8, 23.61, 28.93, 21.32, 27.73, 23.49, 25.49, 35.93, 22.78, 26.14, 20.25, 24.12, 28.68, 24.58, 37.71, 22.55, 25.06, 24.72, 34.1, 32.18, 24.28, 21.75, 29.71, 22.71, 24.75, 30.81, 26.67, 25.99, 31.99, 27.67, 30.29, 28.44, 29.45, 32.13, 32.13, 33.13, 36.29, 38.76, 33.28, 47.87, 46.05, 46.98, 56.52, 55.28, 54.13, 58.65, 65.04, 58.5, 64.98, 58.85, 57.67, 61.9, 58.06, 55.61, 57.2, 55.16, 57.28, 54.83, 56.89, 60.45, 66.15, 68.3, 76.47, 82.26, 83.47, 87.02, 87.68, 87.45, 90.75, 91.69, 90.34, 91.17, 90.69, 89.46, 88.73, 89.7, 88.44, 89.95, 88.18, 87.4, 89.63, 91.34, 92.65, 94.41, 95.09, 94.74, 94.97, 93.33, 92.31, 90.14, 87.53, 86.58, 86.67, 90.44, 89.52, 90.22, 88.1, 89.44, 90.92, 90.23, 86.82, 86.77, 86.58, 83.66, 74.41, 71.64, 69.85, 65.55, 68.27, 60.24, 59.08, 62.03, 56.63, 59.55, 61.0, 56.54, 61.15, 61.59, 63.57, 62.87, 59.92, 54.05, 55.64, 64.04, 67.58, 74.23, 86.0, 86.2, 89.04, 88.57, 88.92, 88.63, 89.47, 88.1, 87.55, 85.02, 86.82, 84.76, 88.53, 90.28, 90.66, 92.02, 91.49, 92.71, 92.28, 92.1, 89.42, 85.69, 80.45, 72.86, 77.12, 74.34, 75.71, 74.06, 72.97, 76.86, 78.13, 81.31, 82.81, 84.8, 88.58, 90.38, 89.76, 91.74, 93.07, 92.89, 93.86, 95.12, 94.56, 94.68, 94.9, 95.38, 93.29, 92.71, 93.34, 92.66, 90.93, 91.29, 89.91, 87.72, 85.19, 84.41, 80.54, 82.81, 79.99, 82.42, 86.13, 84.69, 89.96, 90.34, 95.04, 96.09, 95.6, 95.67, 95.86, 95.68, 95.26, 95.0, 94.73, 93.22, 92.43, 89.85, 87.1, 87.89, 90.31, 93.06, 92.03, 91.04, 90.21, 92.77, 93.93, 92.48, 92.42, 95.09, 94.68, 92.95, 93.93, 94.23, 93.17, 93.17, 95.74, 95.91, 96.57, 95.98, 96.06, 95.82, 95.59, 94.66, 93.02, 92.58, 92.46, 92.7, 93.38, 93.38, 92.7, 94.74, 94.72, 94.33, 93.67, 95.27, 94.76, 94.68, 94.77, 95.17, 95.36, 94.48, 95.27, 95.6, 95.26, 94.57, 96.14, 94.5, 93.92, 94.66, 92.62, 93.49, 92.43, 86.59, 86.35, 84.18, 82.01, 78.27, 81.47, 79.35, 85.7, 85.15, 87.5, 89.45, 87.26, 86.6, 87.99, 89.2, 87.03, 88.1, 89.75, 89.7, 91.12, 90.05, 90.38, 90.97, 92.43, 94.59, 95.81, 95.88, 95.16, 93.05, 86.99, 87.2, 81.91, 85.76, 87.17, 88.28, 86.89, 81.84, 82.62, 85.07, 87.81, 87.56, 88.27, 88.47, 90.5, 91.4, 91.3, 91.57, 92.48, 91.93, 90.45, 91.23, 91.94, 92.14, 91.65, 90.21, 90.96, 90.78, 88.81, 89.52, 92.23, 94.61, 94.4, 92.92, 93.72, 94.33, 92.48, 91.71, 92.07, 91.84, 89.18, 87.6, 87.32, 91.29, 91.74, 91.86, 93.18, 95.1, 93.79, 94.24, 94.68, 94.55, 93.79, 94.35, 93.76, 94.5, 95.27, 94.11, 93.51, 93.33, 93.64, 93.09, 92.27, 90.4, 90.24, 91.52, 89.94, 87.21, 87.15, 86.21, 84.67, 84.36, 82.11, 78.95, 76.29, 78.07, 74.49, 74.74, 65.82, 61.03, 52.74, 54.07, 51.42, 48.57, 42.02, 47.81, 40.79, 35.69, 36.43, 39.01, 40.86, 37.07, 41.51, 39.17, 40.16, 47.67, 42.37, 53.37, 58.09, 73.01, 76.43, 75.33, 77.52, 82.63, 85.64, 80.59, 84.35, 87.47, 86.87, 86.94, 88.89, 89.55, 85.88, 90.09, 88.82, 87.31, 85.1, 90.34, 88.16, 87.69, 88.44, 89.51, 87.11, 83.23, 87.49, 87.55, 82.47, 81.08, 81.29, 73.5, 59.77]
|
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| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 72.035377
| 0.53182
| 1,662
|
O60260
|
O43765
|
23503661
|
DegPred
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
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Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
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Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
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1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
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{}
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SGTA
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MDNKKRLAYAIIQFLHDQLRHGGLSSDAQESLEVAIQCLETAFGVTVEDSDLALPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLREAPSPTGGVGSFDIAGLLNNPGFMSMASNLMNNPQIQQLMSGMISGGNNPLGTPGTSPSQNDLASLIQAGQQFAQQMQQQNPELIEQLRSQIRSRTPSASNDDQQE
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Homo sapiens
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Cytoplasm, Nucleus
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Low tissue specificity
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{'Ciliated cells': '19.8', 'Basal respiratory cells': '19.7', 'Club cells': '19.3', 'Ionocytes': '21.4', 'Mucus glandular cells': '23.8', 'Serous glandular cells': '28.8', 'Gastric mucus-secreting cells': '28.9', 'Proximal enterocytes': '30.3', 'Paneth cells': '31.2', 'Distal enterocytes': '38.0', 'Intestinal goblet cells': '33.9', 'Exocrine glandular cells': '-0.709', 'Basal prostatic cells': '23.0', 'Prostatic glandular cells': '21.1', 'Breast glandular cells': '0.547', 'Breast myoepithelial cells': '0.393', 'Glandular and luminal cells': '31.2', 'Secretory cells': '24.0', 'Basal keratinocytes': '23.3', 'Suprabasal keratinocytes': '24.2', 'Basal squamous epithelial cells': '19.3', 'Squamous epithelial cells': '25.2', 'Alveolar cells type 1': '0.049', 'Alveolar cells type 2': '-0.298', 'Salivary duct cells': '18.1', 'Ductal cells': '0.526', 'Hepatocytes': '-0.111', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.079', 'Distal tubular cells': '40.0', 'Collecting duct cells': '17.5', 'Mesothelial cells': '0.266', 'Sertoli cells': '-0.291', 'Granulosa cells': '23.2', 'Enteroendocrine cells': '29.7', 'Pancreatic endocrine cells': '30.6', 'Leydig cells': '-0.397', 'Excitatory neurons': '9.5', 'Inhibitory neurons': '9.2', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '45.9', 'Bipolar cells': '37.2', 'Horizontal cells': '35.3', 'Astrocytes': '14.6', 'Oligodendrocyte precursor cells': '9.9', 'Oligodendrocytes': '31.8', 'Microglial cells': '4.5', 'Muller glia cells': '37.4', 'Schwann cells': '0.033', 'Spermatogonia': '-0.270', 'Spermatocytes': '-0.061', 'Early spermatids': '0.410', 'Late spermatids': '0.326', 'Oocytes': '19.9', 'Cytotrophoblasts': '55.1', 'Syncytiotrophoblasts': '108.2', 'Extravillous trophoblasts': '54.3', 'Endothelial cells': '26.7', 'Lymphatic endothelial cells': '17.1', 'Cardiomyocytes': '0.539', 'Skeletal myocytes': '-0.177', 'Smooth muscle cells': '23.6', 'Adipocytes': '30.8', 'Melanocytes': '-0.097', 'Fibroblasts': '23.0', 'Peritubular cells': '-0.287', 'Endometrial stromal cells': '23.2', 'Ovarian stromal cells': '32.0', 'Undifferentiated cells': '35.3', 'T-cells': '18.7', 'B-cells': '19.4', 'Plasma cells': '27.0', 'Nk-cells': '15.9', 'Granulocytes': '16.1', 'Monocytes': '29.3', 'Macrophages': '27.0', 'Hofbauer cells': '35.9', 'Kupffer cells': '20.9', 'Dendritic cells': '23.8', 'Langerhans cells': '-0.068', 'Erythroid cells': '-0.050', 'Adipocytes (Subcutaneous)': '-0.011', 'Adipocytes (Visceral)': '-0.040', 'Breast glandular cells (progenitors)': '0.446', 'Adipocytes (Breast)': '-0.395', 'Colon enterocytes': '-0.315', 'Colon enteroendocrine cells': '0.169', 'Enteric glia cells': '0.497', 'Mitotic cells (Colon)': '-0.336', 'Mitotic cells (Heart)': '0.424', 'Podocytes': '-0.136', 'Ascending Loop of Henle cells': '0.450', 'Intercalated cells': '-0.086', 'Cholangiocyte': '0.192', 'NK-cells (Liver)': '-0.195', 'Respiratory ciliated cells': '0.027', 'Mitotic cells (Lung)': '-0.146', 'NK-cells (Lung)': '0.151', 'B-cells (Lung)': '-0.022', 'Alpha cells': '0.369', 'Beta cells': '0.238', 'Prostate glandular cells': '0.109', 'Prostate basal glandular cells': '0.104', 'Urothelial cells': '0.110', 'Keratinocyte (other)': '-0.280', 'Keratinocyte (granular)': '-0.009', 'Hair cortex cells': '0.236', 'Inner root sheath cells': '0.177', 'Outer root sheath cells': '0.198', 'Sebaceous gland cells': '0.027', 'Eccrine sweat gland cells': '0.114', 'Adipocytes (Skin)': '0.272', 'Mitotic cells (Skin)': '-0.037', 'Parietal cells': '-0.665', 'Chief cells': '-0.455', 'Gastric mucous cells': '-0.395', 'Gastric enteroendocrine cells': '-0.362', 'Mitotic cells (Stomach)': '-0.020', 'Parafollicular cells': '0.139', 'Thyroid glandular cells': '0.423', 'Mitotic cells (Thyroid)': '-0.168', 'Adrenal cortex cells': '0.364', 'Adrenal medulla cells': '0.031', 'Mitotic cells (Adrenal gland)': '-0.148', 'Minor salivary glandular cells': '0.494', 'Minor salivary gland ductal cells': '-0.004', 'Minor salivary gland basal cells': '0.203', 'Mitotic cells (Minor salivary gland)': '0.240', 'Adipocytes (Minor salivary gland)': '0.161', 'Somatotropes': '0.019', 'Lactotropes': '0.033', 'Gonadotropes': '-0.072', 'Corticotropes': '0.251', 'Thyrotropes': '0.096', 'Undifferentiated cells (Pituitary gland)': '-0.064', 'Mitotic cells (Spleen)': '-0.255', 'Platelets': '-0.145', 'Erythrocytes': '-0.060', 'Hematopoietic stem cells': '-0.252', 'B-cells (Spleen)': '0.214', 'NK-cells (Spleen)': '0.122', 'Amygdala excitatory': '15.8', 'Cerebellar inhibitory': '22.4', 'Cge interneuron': '19.5', 'Deep-layer corticothalamic and 6b': '17.7', 'Deep-layer intratelencephalic': '17.3', 'Deep-layer near-projecting': '22.0', 'Eccentric medium spiny neuron': '16.7', 'Hippocampal ca1-3': '14.5', 'Hippocampal ca4': '15.9', 'Hippocampal dentate gyrus': '18.4', 'Lamp5-lhx6 and chandelier': '17.6', 'Lower rhombic lip': '14.9', 'Mammillary body': '13.8', 'Medium spiny neuron': '15.1', 'Mge interneuron': '16.7', 'Midbrain-derived inhibitory': '15.5', 'Miscellaneous': '18.4', 'Splatter': '15.3', 'Thalamic excitatory': '17.8', 'Upper rhombic lip': '17.7', 'Upper-layer intratelencephalic': '16.6', 'Astrocyte': '29.4', 'Bergmann glia': '20.5', 'Central nervous system macrophage': '19.4', 'Choroid plexus epithelial cell': '17.3', 'Committed oligodendrocyte precursor': '60.7', 'Ependymal cell': '22.4', 'Oligodendrocyte': '59.1', 'Oligodendrocyte precursor cell': '21.9', 'Endothelial cell': '19.5', 'Pericyte': '19.3', 'Vascular associated smooth muscle cell': '16.9', 'Fibroblast': '18.9', 'Leukocyte': '16.7', 'Basophil': '30.8', 'Eosinophil': '21.0', 'Neutrophil': '50.3', 'Classical monocyte': '25.3', 'Non-classical monocyte': '23.2', 'Intermediate monocyte': '54.6', 'T-reg': '38.9', 'GdT-cell': '17.6', 'MAIT T-cell': '49.0', 'Memory CD4 T-cell': '19.1', 'Naive CD4 T-cell': '17.2', 'Memory CD8 T-cell': '19.1', 'Naive CD8 T-cell': '23.1', 'Memory B-cell': '15.5', 'Naive B-cell': '12.6', 'Plasmacytoid DC': '48.0', 'Myeloid DC': '56.0', 'NK-cell': '23.3', 'Total PBMC': '37.9', 'Vd2 gdTCR': '38.5', 'Memory CD4 T-cell Th1\\/Th17': '18.8', 'Memory CD4 T-cell Th17': '26.0', 'Memory CD4 T-cell Th2': '26.0', 'Non-Vd2 gdTCR': '52.7', 'Memory CD4 T-cell Th1': '30.3', 'Memory CD4 T-cell TFH': '39.7', 'Terminal effector memory CD4 T-cell': '47.9', 'Central memory CD8 T-cell': '32.5', 'Effector memory CD8 T-cell': '49.4', 'Terminal effector memory CD8 T-cell': '42.6', 'Non-switched memory B-cell': '40.4', 'Plasmablast': '73.4', 'Switched memory B-cell': '36.4', 'Exhausted memory B-cell': '34.0', 'Progenitor cell': '44.4', 'Memory T-reg': '43.6', 'Naive CD4 T-cell activated': '33.0', 'Naive CD8 T-cell activated': '40.4', 'Naive T-reg': '27.9'}
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2VYI, 4CPG, 4GOD, 4GOE, 4GOF
|
{'Adipose Tissue': 45.8649584717608, 'Adrenal Gland': 43.35717054263566, 'Bladder': 57.68095238095238, 'Blood': 29.61137029063509, 'Blood Vessel': 54.909617977528086, 'Brain': 54.53849924299773, 'Breast': 52.18884531590414, 'Cervix Uteri': 64.91052631578947, 'Colon': 55.99596919127086, 'Esophagus': 59.366525951557094, 'Fallopian Tube': 67.30777777777777, 'Heart': 43.70188966318234, 'Kidney': 41.416516853932585, 'Liver': 34.65783185840708, 'Lung': 55.11001730103806, 'Muscle': 59.57453300124533, 'Nerve': 71.59337641357028, 'Ovary': 78.79316666666666, 'Pancreas': 27.355844512195123, 'Pituitary': 76.0595406360424, 'Prostate': 69.85179591836734, 'Salivary Gland': 39.334074074074074, 'Skin': 50.04273631840796, 'Small Intestine': 43.4603743315508, 'Spleen': 59.75609958506224, 'Stomach': 44.75161559888579, 'Testis': 88.51002770083102, 'Thyroid': 75.56203675344564, 'Uterus': 78.6580985915493, 'Vagina': 53.89653846153846}
|
[86.6, 87.14, 88.61, 89.01, 89.67, 88.44, 87.46, 83.77, 82.45, 81.33, 82.97, 84.74, 86.57, 89.57, 90.1, 90.69, 89.67, 90.34, 87.71, 89.23, 89.95, 93.02, 92.3, 92.09, 92.37, 91.58, 92.58, 92.83, 92.29, 90.48, 91.02, 91.12, 88.85, 86.99, 87.58, 87.73, 90.05, 90.01, 88.64, 86.82, 89.42, 87.19, 90.11, 87.28, 86.12, 78.81, 73.0, 79.54, 85.09, 87.69, 88.54, 89.59, 88.97, 88.84, 90.12, 86.33, 83.17, 85.28, 79.1, 80.69, 81.01, 82.27, 82.43, 81.52, 86.22, 87.46, 90.66, 87.7, 89.96, 86.4, 86.05, 77.55, 70.82, 62.18, 61.34, 52.16, 38.83, 44.34, 30.73, 31.43, 26.08, 27.82, 32.43, 27.17, 32.44, 31.46, 28.93, 37.69, 33.58, 33.3, 32.79, 32.77, 31.16, 30.63, 29.11, 31.16, 33.22, 35.12, 33.91, 30.34, 35.05, 29.65, 35.87, 27.96, 32.25, 26.15, 30.35, 26.66, 31.89, 33.33, 30.55, 30.74, 35.12, 32.39, 29.71, 33.62, 34.73, 26.72, 31.71, 28.39, 33.89, 31.11, 34.89, 29.86, 26.98, 29.31, 28.71, 29.87, 26.72, 29.64, 28.01, 35.03, 32.42, 26.03, 26.21, 25.78, 27.97, 25.32, 28.69, 42.33, 50.14, 59.81, 73.34, 80.84, 81.26, 91.68, 94.51, 94.99, 94.31, 93.33, 90.47, 88.44, 92.04, 91.72, 91.25, 91.84, 94.01, 93.92, 93.04, 90.7, 89.16, 91.17, 90.11, 90.68, 90.26, 89.74, 92.18, 92.02, 90.56, 89.44, 86.56, 84.44, 85.5, 85.08, 87.47, 89.13, 87.45, 87.73, 87.57, 91.74, 90.15, 90.56, 90.97, 92.39, 92.62, 91.9, 92.26, 92.16, 91.66, 90.75, 92.44, 91.33, 92.54, 90.83, 90.48, 89.4, 89.6, 84.64, 87.28, 87.95, 84.16, 91.86, 89.62, 92.55, 93.61, 92.4, 93.23, 93.33, 92.76, 93.56, 91.0, 92.54, 89.74, 89.48, 89.91, 88.33, 86.79, 86.93, 80.65, 84.69, 87.55, 91.61, 92.58, 92.61, 93.6, 93.85, 92.89, 94.12, 94.58, 91.59, 90.69, 90.31, 84.69, 83.48, 87.8, 89.95, 93.44, 94.32, 93.73, 90.77, 90.73, 91.35, 92.61, 92.07, 91.36, 91.1, 93.93, 94.82, 95.89, 95.03, 95.16, 92.39, 92.77, 90.89, 89.77, 91.95, 94.22, 94.76, 95.62, 95.26, 94.61, 92.28, 93.2, 95.01, 93.32, 91.52, 93.54, 93.31, 91.4, 89.65, 91.18, 89.05, 88.05, 87.94, 88.85, 89.82, 91.79, 92.63, 92.54, 92.06, 89.88, 89.67, 89.07, 91.55, 93.84, 94.98, 95.12, 95.1, 94.48, 92.52, 90.87, 90.19, 92.01, 91.36, 90.6, 93.83, 94.81, 95.01, 93.21, 91.96, 93.44, 92.68, 94.49, 95.0, 93.51, 92.8, 91.23, 90.04, 89.36, 88.14, 90.5, 92.38, 90.6, 90.2, 92.1, 91.02, 89.08, 89.88, 86.7, 86.54, 88.71, 88.57, 86.26, 88.98, 88.9, 88.32, 88.97, 87.29, 88.96, 89.96, 89.35, 88.03, 85.91, 82.77, 75.14, 75.43, 80.18, 79.23, 84.69, 85.78, 87.42, 87.75, 87.16, 87.6, 84.92, 85.06, 88.44, 89.95, 91.76, 90.7, 90.29, 87.05, 79.67, 62.52, 56.91, 60.2, 56.44, 65.23, 71.08, 83.76, 85.05, 87.42, 91.12, 91.7, 91.75, 88.29, 87.13, 85.75, 85.93, 86.7, 89.58, 90.19, 90.4, 86.67, 89.15, 87.4, 86.34, 78.61, 70.66, 66.43, 65.14, 58.91, 50.78, 46.67, 36.54, 35.27, 32.59, 40.61, 47.31, 50.77, 62.41, 70.48, 78.66, 85.25, 86.67, 88.92, 89.3, 88.85, 87.79, 87.66, 89.94, 91.09, 85.42, 72.16, 57.86, 51.98, 52.44, 47.51, 45.51, 48.58, 51.24, 52.02, 56.52, 70.54, 78.5, 85.42, 88.76, 89.24, 92.22, 89.92, 91.66, 88.73, 88.39, 87.92, 87.02, 85.8, 83.44, 74.02, 80.21, 84.48, 87.59, 88.21, 89.27, 90.78, 91.24, 91.53, 90.4, 90.16, 90.37, 90.19, 90.87, 89.71, 92.15, 92.34, 93.0, 92.02, 89.02, 86.0, 88.39, 88.77, 90.21, 92.62, 91.03, 89.53, 85.52, 87.96, 88.06, 86.94, 83.84, 86.53, 86.56, 87.5, 88.23, 82.06, 76.01]
|
[0.3, 0.19, 0.02, 0.02, 0.0, 0.08, 0.07, 0.12, 0.1, 0.29, 0.13, 0.0, 0.08, 0.4, 0.08, 0.86, 0.06, 0.64, 0.51, 0.76, 0.17, 0.23, 0.0, 0.42, 0.46, 0.04, 0.05, 0.38, 0.51, 0.01, 0.11, 0.81, 0.61, 0.34, 0.79, 0.2, 0.5, 0.2, 0.8, 0.29, 0.02, 0.07, 0.0, 0.01, 0.15, 0.37, 0.23, 0.67, 0.42, 0.05, 0.57, 0.41, 0.67, 0.4, 0.24, 0.03, 0.72, 0.65, 0.11, 0.71, 0.08, 0.66, 0.59, 0.49, 0.11, 0.22, 0.01, 0.08, 0.0, 0.01, 0.37, 0.2, 0.55, 0.58, 0.7, 0.7, 0.84, 0.57, 0.73, 0.81, 0.94, 0.84, 0.96, 0.99, 0.81, 0.96, 0.91, 0.93, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.85, 1.0, 0.81, 1.0, 0.98, 1.0, 1.0, 0.92, 0.96, 0.94, 0.94, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 0.97, 0.92, 0.92, 0.75, 0.78, 0.77, 0.81, 0.93, 0.83, 0.96, 0.85, 0.98, 0.87, 0.9, 0.95, 0.92, 0.95, 0.89, 0.92, 0.71, 0.94, 0.91, 0.74, 0.82, 0.75, 0.29, 0.14, 0.04, 0.0, 0.11, 0.0, 0.06, 0.01, 0.58, 0.68, 0.79, 0.26, 0.47, 0.55, 0.25, 0.12, 0.33, 0.01, 0.29, 0.0, 0.29, 0.17, 0.19, 0.0, 0.34, 0.62, 0.34, 0.7, 0.44, 0.77, 0.3, 0.1, 0.56, 0.2, 0.72, 0.7, 0.29, 0.0, 0.35, 0.39, 0.12, 0.55, 0.1, 0.09, 0.46, 0.53, 0.91, 0.61, 0.66, 0.06, 0.52, 0.15, 0.67, 0.09, 0.58, 0.2, 0.92, 0.94, 0.2, 0.75, 0.03, 0.58, 0.27, 0.07, 0.36, 0.13, 0.14, 0.05, 0.08, 0.01, 0.27, 0.61, 0.25, 0.98, 0.26, 0.48, 0.67, 0.89, 0.48, 0.65, 0.17, 0.33, 0.13, 0.0, 0.25, 0.06, 0.0, 0.07, 0.24, 0.07, 0.57, 0.29, 0.62, 0.08, 0.21, 0.03, 0.02, 0.38, 0.34, 0.49, 0.4, 0.52, 0.22, 0.35, 0.18, 0.03, 0.0, 0.11, 0.01, 0.36, 0.01, 0.91, 0.29, 0.35, 0.05, 0.0, 0.0, 0.04, 0.15, 0.22, 0.12, 0.0, 0.06, 0.1, 0.06, 0.0, 0.0, 0.06, 0.12, 0.05, 0.0, 0.23, 0.21, 0.37, 0.08, 0.41, 0.59, 0.35, 0.85, 0.96, 0.29, 0.3, 0.17, 0.0, 0.01, 0.25, 0.01, 0.06, 0.39, 0.69, 0.21, 0.89, 0.89, 0.02, 0.23, 0.02, 0.66, 0.33, 0.25, 0.35, 0.0, 0.0, 0.22, 0.15, 0.08, 0.26, 0.49, 0.63, 0.07, 0.1, 0.55, 0.22, 0.1, 0.6, 0.58, 0.02, 0.34, 0.5, 0.15, 0.19, 0.41, 0.17, 0.36, 0.74, 0.62, 0.43, 0.18, 0.07, 0.12, 0.04, 0.09, 0.48, 0.45, 0.84, 0.29, 0.3, 0.3, 0.5, 0.1, 0.62, 0.25, 0.79, 0.77, 0.95, 0.45, 0.33, 0.46, 0.03, 0.36, 0.02, 0.78, 0.39, 0.94, 0.86, 0.76, 0.8, 0.31, 0.26, 0.61, 0.25, 0.31, 0.0, 0.0, 0.26, 0.69, 0.1, 0.33, 0.4, 0.53, 0.34, 0.3, 0.81, 0.61, 0.91, 0.29, 0.58, 0.75, 0.28, 0.48, 0.19, 0.6, 0.79, 0.73, 0.43, 0.82, 0.53, 0.59, 0.64, 0.21, 0.83, 0.24, 0.61, 0.77, 0.74, 0.06, 0.14, 0.6, 0.56, 0.0, 0.4, 0.08, 0.56, 0.62, 0.3, 0.5, 0.86, 0.92, 0.48, 0.7, 0.74, 0.73, 0.51, 0.52, 0.31, 0.61, 0.0, 0.37, 0.59, 0.36, 0.65, 0.32, 0.69, 0.07, 0.6, 0.25, 0.76, 0.64, 0.19, 0.13, 0.03, 0.35, 0.08, 0.61, 0.05, 0.67, 0.47, 0.64, 0.99, 0.12, 0.63, 0.08, 0.36, 0.02, 0.0, 0.08, 0.5, 0.34, 0.38, 0.36, 0.68, 0.18, 0.4, 0.75, 0.63, 0.04, 0.25, 0.01, 0.14, 0.06, 0.05, 0.01, 0.45, 0.31]
|
[49.12, 76.88, 84.57, 90.35, 92.64, 90.66, 92.2, 94.34, 93.92, 93.25, 94.89, 94.6, 93.05, 94.33, 94.76, 93.36, 91.72, 92.48, 91.14, 88.76, 85.81, 77.33, 85.12, 88.44, 91.72, 90.54, 92.11, 92.88, 92.72, 93.15, 94.39, 94.65, 94.78, 96.62, 96.31, 96.0, 95.81, 96.68, 95.79, 95.74, 95.71, 95.52, 94.62, 93.56, 92.8, 90.98, 87.13, 88.25, 88.8, 86.92, 88.51, 87.74, 85.64, 82.38, 81.68, 80.15, 88.49, 88.97, 87.93, 85.95, 86.3, 86.37, 84.53, 75.6, 78.22, 78.52, 72.37, 56.48, 46.95, 42.68, 42.46, 37.88, 40.41, 35.11, 41.66, 35.76, 41.85, 39.46, 38.98, 55.26, 63.61, 78.48, 82.99, 90.71, 92.53, 94.74, 94.87, 94.56, 96.87, 97.83, 97.69, 97.89, 98.4, 98.59, 98.5, 98.59, 98.57, 98.68, 98.63, 98.72, 98.7, 98.55, 98.48, 98.38, 98.18, 98.34, 98.53, 98.28, 97.97, 98.64, 98.42, 98.3, 98.57, 98.59, 97.68, 97.57, 97.56, 96.04, 94.91, 94.29, 92.74, 91.79, 92.55, 94.43, 97.02, 98.2, 98.18, 98.37, 98.5, 98.67, 98.72, 98.61, 98.65, 98.68, 98.55, 98.34, 98.45, 98.22, 97.17, 96.73, 97.48, 94.73, 93.23, 97.59, 97.45, 95.42, 96.64, 97.47, 96.66, 95.69, 96.79, 96.79, 94.38, 92.71, 95.95, 95.68, 97.26, 97.51, 98.32, 98.41, 98.22, 98.64, 98.58, 98.51, 98.27, 98.31, 98.3, 97.99, 97.92, 97.37, 97.25, 95.47, 94.17, 93.49, 95.5, 94.72, 94.07, 97.49, 98.14, 97.63, 97.95, 98.66, 98.51, 98.19, 98.44, 98.52, 98.4, 98.12, 98.0, 97.98, 97.89, 98.0, 98.21, 97.83, 98.34, 98.63, 98.42, 98.17, 98.29, 97.97, 96.99, 96.69, 96.89, 95.61, 94.25, 90.05, 90.12, 85.69, 70.93, 59.7, 50.45, 49.77, 45.67, 40.67, 36.49, 42.68, 48.35, 46.36, 55.41, 64.93, 61.67, 67.19, 70.52, 65.74, 70.69, 75.58, 73.08, 77.1, 76.32, 76.22, 77.46, 77.36, 75.66, 76.77, 78.79, 78.65, 73.51, 75.23, 79.84, 74.89, 78.46, 76.53, 73.03, 74.62, 74.1, 70.66, 63.9, 65.46, 67.61, 58.36, 60.24, 61.06, 51.25, 46.81, 44.97, 44.42, 39.74, 40.31, 38.13, 32.97, 39.47, 40.29, 41.33, 43.06, 42.79, 49.43, 55.86, 61.98, 63.02, 61.52, 72.39, 73.31, 71.74, 76.32, 78.85, 74.62, 75.27, 78.23, 78.11, 77.05, 73.27, 78.41, 76.68, 70.66, 76.44, 76.97, 74.05, 72.57, 77.37, 78.55, 73.86, 71.53, 74.86, 74.58, 73.79, 75.79, 76.54, 71.23, 72.37, 70.72, 69.52, 55.22, 45.85, 45.19, 40.68, 42.18, 40.35, 38.86, 44.12, 44.13, 38.85, 44.38, 47.89]
|
[0.87, 0.46, 0.74, 0.69, 0.4, 0.34, 0.54, 0.04, 0.07, 0.15, 0.32, 0.0, 0.39, 0.35, 0.13, 0.27, 0.48, 0.31, 0.2, 0.87, 0.79, 0.39, 0.9, 0.39, 0.63, 0.57, 0.7, 0.28, 0.34, 0.58, 0.56, 0.19, 0.56, 0.58, 0.34, 0.05, 0.62, 0.58, 0.21, 0.19, 0.72, 0.8, 0.41, 0.58, 0.01, 0.37, 0.4, 0.8, 0.28, 0.63, 0.77, 0.07, 0.46, 0.45, 0.96, 0.48, 0.52, 0.32, 0.4, 0.48, 0.41, 0.71, 0.64, 0.3, 0.72, 0.67, 0.61, 0.71, 0.72, 0.76, 0.6, 0.77, 0.78, 0.7, 0.46, 0.83, 0.73, 0.64, 0.88, 0.74, 0.92, 0.93, 0.35, 0.43, 0.84, 0.79, 0.34, 0.26, 0.39, 0.35, 0.0, 0.37, 0.59, 0.09, 0.19, 0.5, 0.37, 0.0, 0.3, 0.43, 0.17, 0.23, 0.69, 0.69, 0.66, 0.38, 0.16, 0.65, 0.2, 0.0, 0.16, 0.54, 0.24, 0.02, 0.14, 0.4, 0.0, 0.11, 0.76, 0.32, 0.13, 0.3, 0.62, 0.23, 0.06, 0.32, 0.01, 0.08, 0.0, 0.14, 0.17, 0.01, 0.19, 0.0, 0.18, 0.17, 0.63, 0.38, 0.42, 0.38, 0.27, 0.49, 0.1, 0.01, 0.15, 0.65, 0.06, 0.01, 0.5, 0.23, 0.0, 0.16, 0.56, 0.3, 0.42, 0.52, 0.62, 0.18, 0.15, 0.54, 0.0, 0.09, 0.11, 0.25, 0.01, 0.0, 0.43, 0.0, 0.07, 0.2, 0.37, 0.4, 0.7, 0.43, 0.15, 0.64, 0.46, 0.0, 0.11, 0.57, 0.32, 0.01, 0.47, 0.36, 0.0, 0.15, 0.64, 0.36, 0.34, 0.56, 0.81, 0.21, 0.62, 0.62, 0.09, 0.37, 0.49, 0.21, 0.13, 0.65, 0.52, 0.02, 0.43, 0.37, 0.47, 0.46, 0.79, 0.65, 0.49, 0.83, 0.69, 0.89, 0.79, 0.69, 0.52, 0.97, 0.9, 0.7, 0.75, 0.58, 0.61, 0.64, 0.46, 0.26, 0.54, 0.81, 0.5, 0.72, 0.39, 0.38, 0.55, 0.47, 0.29, 0.22, 0.43, 0.42, 0.39, 0.6, 0.65, 0.22, 0.61, 0.57, 0.32, 0.54, 0.7, 0.61, 0.51, 0.51, 0.48, 0.77, 0.78, 0.72, 0.66, 0.81, 0.91, 0.88, 0.98, 0.9, 1.0, 0.98, 0.91, 0.93, 0.87, 0.89, 0.88, 0.48, 0.83, 0.73, 0.56, 0.63, 0.46, 0.48, 0.68, 0.54, 0.62, 0.49, 0.45, 0.59, 0.53, 0.46, 0.46, 0.59, 0.39, 0.18, 0.6, 0.84, 0.52, 0.36, 0.58, 0.7, 0.34, 0.24, 0.57, 0.54, 0.43, 0.57, 0.51, 0.62, 0.64, 0.76, 0.73, 0.85, 0.68, 0.85, 0.85, 0.84, 0.86, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0]
| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 81.366166
| 0.47738
| 2,332
|
O60260
|
O43819
|
33082525
|
DegPred
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
|
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
|
{}
|
SCO2
|
MLLLTRSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTRLLITGLFGAGLGGAWLALRAEKERLQQQKRTEALRQAAVGQGDFHLLDHRGRARCKADFRGQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARYVQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSRSAEQISDSVRRHMAAFRSVLS
|
Homo sapiens
|
Mitochondrion inner membrane
|
Low tissue specificity
|
{}
|
2RLI
|
{'Adipose Tissue': 23.547697674418604, 'Adrenal Gland': 18.25162403100775, 'Bladder': 13.333428571428572, 'Blood': 25.651899246501618, 'Blood Vessel': 13.48247490636704, 'Brain': 8.156606850870553, 'Breast': 18.520089324618738, 'Cervix Uteri': 17.02321052631579, 'Colon': 19.22888703465982, 'Esophagus': 20.22455017301038, 'Fallopian Tube': 75.26977777777778, 'Heart': 9.642894425087109, 'Kidney': 17.71738202247191, 'Liver': 16.142743362831858, 'Lung': 39.18625259515571, 'Muscle': 8.883624906600248, 'Nerve': 15.271407108239096, 'Ovary': 6.823715000000001, 'Pancreas': 5.3489807926829265, 'Pituitary': 12.460374558303888, 'Prostate': 14.357714285714286, 'Salivary Gland': 19.807895061728395, 'Skin': 22.62052017689331, 'Small Intestine': 19.164566844919783, 'Spleen': 26.51579253112033, 'Stomach': 11.929440111420613, 'Testis': 13.30206537396122, 'Thyroid': 17.125030627871364, 'Uterus': 12.78161267605634, 'Vagina': 18.49767948717949}
|
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|
[42.81, 39.03, 42.1, 46.03, 45.59, 41.56, 45.24, 44.81, 52.26, 44.62, 40.73, 45.82, 48.58, 44.73, 51.57, 46.86, 42.41, 39.71, 41.41, 37.44, 36.71, 40.37, 37.02, 29.73, 31.79, 28.95, 26.13, 26.48, 33.46, 30.64, 36.54, 28.65, 37.31, 31.96, 32.51, 34.07, 39.19, 42.32, 38.14, 42.91, 34.95, 37.25, 43.0, 43.57, 45.45, 47.91, 41.03, 44.33, 51.59, 49.57, 57.73, 60.08, 70.48, 72.29, 79.2, 90.03, 90.43, 90.83, 92.85, 92.06, 95.13, 96.28, 95.15, 95.13, 96.73, 97.35, 97.27, 97.11, 97.74, 97.91, 97.91, 97.83, 98.03, 97.67, 97.19, 97.14, 96.51, 96.99, 96.43, 94.73, 94.15, 95.93, 91.22, 89.96, 91.62, 89.27, 81.5, 82.61, 87.05, 79.37, 77.16, 79.26, 79.31, 72.26, 72.17, 74.49, 71.27, 73.24, 80.62, 80.14, 75.93, 80.73, 88.28, 93.44, 96.22, 98.21, 98.46, 98.28, 97.91, 97.99, 97.37, 98.1, 98.06, 97.68, 95.6, 91.84, 92.56, 95.48, 94.98, 92.07, 94.15, 96.05, 97.7, 98.05, 98.38, 97.42, 98.04, 97.81, 97.58, 97.35, 96.35, 94.13, 93.61, 90.31, 90.02, 93.47, 94.43, 96.15, 96.8, 97.59, 96.76, 97.57, 98.12, 98.25, 97.95, 98.24, 98.57, 98.31, 97.91, 97.85, 97.86, 96.51, 96.6, 95.35, 92.38, 92.8, 94.78, 94.41, 94.28, 98.03, 98.28, 98.49, 98.4, 98.39, 98.16, 98.4, 97.57, 97.29, 97.42, 95.66, 96.22, 97.89, 97.46, 98.26, 98.18, 97.9, 98.14, 98.11, 97.83, 97.7, 97.39, 96.64, 95.22, 97.05, 97.33, 96.79, 96.53, 98.33, 98.28, 98.39, 98.59, 98.41, 97.73, 97.72, 96.99, 96.95, 97.44, 97.4, 95.84, 95.33, 95.61, 95.1, 93.04, 92.04, 91.75, 90.11, 94.0, 94.01, 95.83, 95.43, 93.47, 91.76, 92.19, 93.07, 91.71, 92.39, 91.05, 88.64, 90.46, 93.59, 93.58, 94.92, 93.84, 94.6, 94.18, 93.9, 95.17, 97.65, 95.91, 96.4, 94.9, 93.99, 94.47, 91.11, 90.17, 89.98, 91.8, 91.24, 93.85, 94.69, 96.14, 94.53, 94.48, 95.35, 96.99, 97.92, 98.28, 98.18, 98.3, 98.48, 98.27, 97.95, 97.35, 98.05, 97.46, 96.25, 96.23, 96.35, 95.1, 92.33, 93.05, 89.36, 86.56, 84.04, 76.55, 64.18]
|
[0.95, 0.9, 0.91, 0.91, 0.98, 0.97, 0.88, 0.85, 0.86, 0.8, 0.92, 0.81, 0.9, 0.85, 0.79, 0.86, 0.85, 0.92, 0.85, 0.89, 0.87, 0.87, 0.91, 0.98, 0.98, 1.0, 1.0, 1.0, 0.98, 0.96, 0.96, 0.96, 0.97, 0.98, 1.0, 0.95, 1.0, 0.89, 0.91, 0.93, 0.95, 0.85, 0.84, 0.87, 0.86, 0.87, 0.76, 0.8, 0.91, 0.7, 0.88, 0.88, 0.94, 0.61, 0.56, 0.56, 0.71, 0.83, 0.47, 0.53, 0.6, 0.66, 0.45, 0.59, 0.5, 0.71, 0.63, 0.5, 0.61, 0.53, 0.66, 0.36, 0.44, 0.44, 0.62, 0.66, 0.55, 0.63, 0.52, 0.39, 0.57, 0.63, 0.49, 0.69, 0.45, 0.53, 0.46, 0.63, 0.68, 0.34, 0.35, 0.54, 0.48, 0.16, 0.74, 0.69, 0.21, 0.38, 0.15, 0.02, 0.68, 0.31, 0.39, 0.01, 0.54, 0.02, 0.39, 0.0, 0.15, 0.7, 0.49, 0.46, 0.75, 0.25, 0.22, 0.14, 0.42, 0.48, 0.07, 0.64, 0.65, 0.34, 0.04, 0.02, 0.01, 0.01, 0.0, 0.0, 0.0, 0.01, 0.17, 0.49, 0.22, 0.67, 0.69, 0.44, 0.0, 0.21, 0.62, 0.05, 0.0, 0.59, 0.11, 0.0, 0.05, 0.51, 0.01, 0.01, 0.56, 0.31, 0.03, 0.45, 0.7, 0.33, 0.92, 0.95, 0.34, 0.48, 0.62, 0.02, 0.15, 0.0, 0.0, 0.0, 0.0, 0.0, 0.05, 0.04, 0.19, 0.77, 0.2, 0.0, 0.54, 0.28, 0.69, 0.08, 0.0, 0.25, 0.6, 0.13, 0.03, 0.75, 0.9, 0.16, 0.08, 0.87, 0.28, 0.02, 0.13, 0.0, 0.0, 0.03, 0.26, 0.46, 0.52, 0.8, 0.36, 0.01, 0.31, 0.47, 0.01, 0.0, 0.77, 0.16, 0.01, 0.63, 0.08, 0.55, 0.37, 0.52, 0.64, 0.46, 0.91, 0.61, 0.51, 0.95, 0.88, 0.62, 0.46, 0.14, 0.66, 0.05, 0.59, 0.15, 0.23, 0.25, 0.17, 0.01, 0.07, 0.0, 0.04, 0.12, 0.15, 0.15, 0.06, 0.46, 0.15, 0.24, 0.04, 0.55, 0.04, 0.32, 0.64, 0.91, 0.48, 0.44, 0.04, 0.64, 0.45, 0.0, 0.0, 0.41, 0.08, 0.0, 0.26, 0.62, 0.18, 0.13, 0.68, 0.67, 0.27, 0.82, 0.34, 0.71, 0.73, 0.8]
| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 83.33906
| 0.47218
| 2,507
|
O60260
|
O60260
|
15252205, PRKN2_HUMAN, 23503661
|
UbiNet, UbiBrowser, DegPred
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
|
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
|
{}
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
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1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
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{}
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[86.6, 87.14, 88.61, 89.01, 89.67, 88.44, 87.46, 83.77, 82.45, 81.33, 82.97, 84.74, 86.57, 89.57, 90.1, 90.69, 89.67, 90.34, 87.71, 89.23, 89.95, 93.02, 92.3, 92.09, 92.37, 91.58, 92.58, 92.83, 92.29, 90.48, 91.02, 91.12, 88.85, 86.99, 87.58, 87.73, 90.05, 90.01, 88.64, 86.82, 89.42, 87.19, 90.11, 87.28, 86.12, 78.81, 73.0, 79.54, 85.09, 87.69, 88.54, 89.59, 88.97, 88.84, 90.12, 86.33, 83.17, 85.28, 79.1, 80.69, 81.01, 82.27, 82.43, 81.52, 86.22, 87.46, 90.66, 87.7, 89.96, 86.4, 86.05, 77.55, 70.82, 62.18, 61.34, 52.16, 38.83, 44.34, 30.73, 31.43, 26.08, 27.82, 32.43, 27.17, 32.44, 31.46, 28.93, 37.69, 33.58, 33.3, 32.79, 32.77, 31.16, 30.63, 29.11, 31.16, 33.22, 35.12, 33.91, 30.34, 35.05, 29.65, 35.87, 27.96, 32.25, 26.15, 30.35, 26.66, 31.89, 33.33, 30.55, 30.74, 35.12, 32.39, 29.71, 33.62, 34.73, 26.72, 31.71, 28.39, 33.89, 31.11, 34.89, 29.86, 26.98, 29.31, 28.71, 29.87, 26.72, 29.64, 28.01, 35.03, 32.42, 26.03, 26.21, 25.78, 27.97, 25.32, 28.69, 42.33, 50.14, 59.81, 73.34, 80.84, 81.26, 91.68, 94.51, 94.99, 94.31, 93.33, 90.47, 88.44, 92.04, 91.72, 91.25, 91.84, 94.01, 93.92, 93.04, 90.7, 89.16, 91.17, 90.11, 90.68, 90.26, 89.74, 92.18, 92.02, 90.56, 89.44, 86.56, 84.44, 85.5, 85.08, 87.47, 89.13, 87.45, 87.73, 87.57, 91.74, 90.15, 90.56, 90.97, 92.39, 92.62, 91.9, 92.26, 92.16, 91.66, 90.75, 92.44, 91.33, 92.54, 90.83, 90.48, 89.4, 89.6, 84.64, 87.28, 87.95, 84.16, 91.86, 89.62, 92.55, 93.61, 92.4, 93.23, 93.33, 92.76, 93.56, 91.0, 92.54, 89.74, 89.48, 89.91, 88.33, 86.79, 86.93, 80.65, 84.69, 87.55, 91.61, 92.58, 92.61, 93.6, 93.85, 92.89, 94.12, 94.58, 91.59, 90.69, 90.31, 84.69, 83.48, 87.8, 89.95, 93.44, 94.32, 93.73, 90.77, 90.73, 91.35, 92.61, 92.07, 91.36, 91.1, 93.93, 94.82, 95.89, 95.03, 95.16, 92.39, 92.77, 90.89, 89.77, 91.95, 94.22, 94.76, 95.62, 95.26, 94.61, 92.28, 93.2, 95.01, 93.32, 91.52, 93.54, 93.31, 91.4, 89.65, 91.18, 89.05, 88.05, 87.94, 88.85, 89.82, 91.79, 92.63, 92.54, 92.06, 89.88, 89.67, 89.07, 91.55, 93.84, 94.98, 95.12, 95.1, 94.48, 92.52, 90.87, 90.19, 92.01, 91.36, 90.6, 93.83, 94.81, 95.01, 93.21, 91.96, 93.44, 92.68, 94.49, 95.0, 93.51, 92.8, 91.23, 90.04, 89.36, 88.14, 90.5, 92.38, 90.6, 90.2, 92.1, 91.02, 89.08, 89.88, 86.7, 86.54, 88.71, 88.57, 86.26, 88.98, 88.9, 88.32, 88.97, 87.29, 88.96, 89.96, 89.35, 88.03, 85.91, 82.77, 75.14, 75.43, 80.18, 79.23, 84.69, 85.78, 87.42, 87.75, 87.16, 87.6, 84.92, 85.06, 88.44, 89.95, 91.76, 90.7, 90.29, 87.05, 79.67, 62.52, 56.91, 60.2, 56.44, 65.23, 71.08, 83.76, 85.05, 87.42, 91.12, 91.7, 91.75, 88.29, 87.13, 85.75, 85.93, 86.7, 89.58, 90.19, 90.4, 86.67, 89.15, 87.4, 86.34, 78.61, 70.66, 66.43, 65.14, 58.91, 50.78, 46.67, 36.54, 35.27, 32.59, 40.61, 47.31, 50.77, 62.41, 70.48, 78.66, 85.25, 86.67, 88.92, 89.3, 88.85, 87.79, 87.66, 89.94, 91.09, 85.42, 72.16, 57.86, 51.98, 52.44, 47.51, 45.51, 48.58, 51.24, 52.02, 56.52, 70.54, 78.5, 85.42, 88.76, 89.24, 92.22, 89.92, 91.66, 88.73, 88.39, 87.92, 87.02, 85.8, 83.44, 74.02, 80.21, 84.48, 87.59, 88.21, 89.27, 90.78, 91.24, 91.53, 90.4, 90.16, 90.37, 90.19, 90.87, 89.71, 92.15, 92.34, 93.0, 92.02, 89.02, 86.0, 88.39, 88.77, 90.21, 92.62, 91.03, 89.53, 85.52, 87.96, 88.06, 86.94, 83.84, 86.53, 86.56, 87.5, 88.23, 82.06, 76.01]
|
[0.3, 0.19, 0.02, 0.02, 0.0, 0.08, 0.07, 0.12, 0.1, 0.29, 0.13, 0.0, 0.08, 0.4, 0.08, 0.86, 0.06, 0.64, 0.51, 0.76, 0.17, 0.23, 0.0, 0.42, 0.46, 0.04, 0.05, 0.38, 0.51, 0.01, 0.11, 0.81, 0.61, 0.34, 0.79, 0.2, 0.5, 0.2, 0.8, 0.29, 0.02, 0.07, 0.0, 0.01, 0.15, 0.37, 0.23, 0.67, 0.42, 0.05, 0.57, 0.41, 0.67, 0.4, 0.24, 0.03, 0.72, 0.65, 0.11, 0.71, 0.08, 0.66, 0.59, 0.49, 0.11, 0.22, 0.01, 0.08, 0.0, 0.01, 0.37, 0.2, 0.55, 0.58, 0.7, 0.7, 0.84, 0.57, 0.73, 0.81, 0.94, 0.84, 0.96, 0.99, 0.81, 0.96, 0.91, 0.93, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.85, 1.0, 0.81, 1.0, 0.98, 1.0, 1.0, 0.92, 0.96, 0.94, 0.94, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 0.97, 0.92, 0.92, 0.75, 0.78, 0.77, 0.81, 0.93, 0.83, 0.96, 0.85, 0.98, 0.87, 0.9, 0.95, 0.92, 0.95, 0.89, 0.92, 0.71, 0.94, 0.91, 0.74, 0.82, 0.75, 0.29, 0.14, 0.04, 0.0, 0.11, 0.0, 0.06, 0.01, 0.58, 0.68, 0.79, 0.26, 0.47, 0.55, 0.25, 0.12, 0.33, 0.01, 0.29, 0.0, 0.29, 0.17, 0.19, 0.0, 0.34, 0.62, 0.34, 0.7, 0.44, 0.77, 0.3, 0.1, 0.56, 0.2, 0.72, 0.7, 0.29, 0.0, 0.35, 0.39, 0.12, 0.55, 0.1, 0.09, 0.46, 0.53, 0.91, 0.61, 0.66, 0.06, 0.52, 0.15, 0.67, 0.09, 0.58, 0.2, 0.92, 0.94, 0.2, 0.75, 0.03, 0.58, 0.27, 0.07, 0.36, 0.13, 0.14, 0.05, 0.08, 0.01, 0.27, 0.61, 0.25, 0.98, 0.26, 0.48, 0.67, 0.89, 0.48, 0.65, 0.17, 0.33, 0.13, 0.0, 0.25, 0.06, 0.0, 0.07, 0.24, 0.07, 0.57, 0.29, 0.62, 0.08, 0.21, 0.03, 0.02, 0.38, 0.34, 0.49, 0.4, 0.52, 0.22, 0.35, 0.18, 0.03, 0.0, 0.11, 0.01, 0.36, 0.01, 0.91, 0.29, 0.35, 0.05, 0.0, 0.0, 0.04, 0.15, 0.22, 0.12, 0.0, 0.06, 0.1, 0.06, 0.0, 0.0, 0.06, 0.12, 0.05, 0.0, 0.23, 0.21, 0.37, 0.08, 0.41, 0.59, 0.35, 0.85, 0.96, 0.29, 0.3, 0.17, 0.0, 0.01, 0.25, 0.01, 0.06, 0.39, 0.69, 0.21, 0.89, 0.89, 0.02, 0.23, 0.02, 0.66, 0.33, 0.25, 0.35, 0.0, 0.0, 0.22, 0.15, 0.08, 0.26, 0.49, 0.63, 0.07, 0.1, 0.55, 0.22, 0.1, 0.6, 0.58, 0.02, 0.34, 0.5, 0.15, 0.19, 0.41, 0.17, 0.36, 0.74, 0.62, 0.43, 0.18, 0.07, 0.12, 0.04, 0.09, 0.48, 0.45, 0.84, 0.29, 0.3, 0.3, 0.5, 0.1, 0.62, 0.25, 0.79, 0.77, 0.95, 0.45, 0.33, 0.46, 0.03, 0.36, 0.02, 0.78, 0.39, 0.94, 0.86, 0.76, 0.8, 0.31, 0.26, 0.61, 0.25, 0.31, 0.0, 0.0, 0.26, 0.69, 0.1, 0.33, 0.4, 0.53, 0.34, 0.3, 0.81, 0.61, 0.91, 0.29, 0.58, 0.75, 0.28, 0.48, 0.19, 0.6, 0.79, 0.73, 0.43, 0.82, 0.53, 0.59, 0.64, 0.21, 0.83, 0.24, 0.61, 0.77, 0.74, 0.06, 0.14, 0.6, 0.56, 0.0, 0.4, 0.08, 0.56, 0.62, 0.3, 0.5, 0.86, 0.92, 0.48, 0.7, 0.74, 0.73, 0.51, 0.52, 0.31, 0.61, 0.0, 0.37, 0.59, 0.36, 0.65, 0.32, 0.69, 0.07, 0.6, 0.25, 0.76, 0.64, 0.19, 0.13, 0.03, 0.35, 0.08, 0.61, 0.05, 0.67, 0.47, 0.64, 0.99, 0.12, 0.63, 0.08, 0.36, 0.02, 0.0, 0.08, 0.5, 0.34, 0.38, 0.36, 0.68, 0.18, 0.4, 0.75, 0.63, 0.04, 0.25, 0.01, 0.14, 0.06, 0.05, 0.01, 0.45, 0.31]
| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 78.482559
| 0.425398
| 1,708
|
O60260
|
O60488
|
33082525, 23503661
|
DegPred
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
|
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
|
{}
|
ACSL4
|
MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK
|
Homo sapiens
|
Mitochondrion outer membrane, Peroxisome membrane, Microsome membrane, Endoplasmic reticulum membrane, Cell membrane
|
Low tissue specificity
|
{'Ciliated cells': '26.6', 'Basal respiratory cells': '19.8', 'Club cells': '21.4', 'Ionocytes': '9.9', 'Mucus glandular cells': '12.0', 'Serous glandular cells': '20.3', 'Gastric mucus-secreting cells': '7.1', 'Proximal enterocytes': '0.6', 'Paneth cells': '1.6', 'Distal enterocytes': '0.3', 'Intestinal goblet cells': '3.1', 'Exocrine glandular cells': '-0.649', 'Basal prostatic cells': '11.4', 'Prostatic glandular cells': '6.3', 'Breast glandular cells': '-0.185', 'Breast myoepithelial cells': '-0.115', 'Glandular and luminal cells': '219.0', 'Secretory cells': '40.9', 'Basal keratinocytes': '27.2', 'Suprabasal keratinocytes': '6.4', 'Basal squamous epithelial cells': '45.4', 'Squamous epithelial cells': '6.7', 'Alveolar cells type 1': '0.034', 'Alveolar cells type 2': '0.237', 'Salivary duct cells': '39.8', 'Ductal cells': '0.696', 'Hepatocytes': '0.036', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.147', 'Distal tubular cells': '76.8', 'Collecting duct cells': '72.0', 'Mesothelial cells': '0.056', 'Sertoli cells': '0.791', 'Granulosa cells': '50.7', 'Enteroendocrine cells': '5.4', 'Pancreatic endocrine cells': '34.0', 'Leydig cells': '0.607', 'Excitatory neurons': '74.1', 'Inhibitory neurons': '75.0', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '11.0', 'Bipolar cells': '36.9', 'Horizontal cells': '15.1', 'Astrocytes': '27.6', 'Oligodendrocyte precursor cells': '67.0', 'Oligodendrocytes': '108.3', 'Microglial cells': '54.6', 'Muller glia cells': '11.8', 'Schwann cells': '0.033', 'Spermatogonia': '0.552', 'Spermatocytes': '0.257', 'Early spermatids': '-0.417', 'Late spermatids': '-0.647', 'Oocytes': '3.7', 'Cytotrophoblasts': '7.6', 'Syncytiotrophoblasts': '37.2', 'Extravillous trophoblasts': '43.9', 'Endothelial cells': '30.6', 'Lymphatic endothelial cells': '23.1', 'Cardiomyocytes': '0.537', 'Skeletal myocytes': '-0.328', 'Smooth muscle cells': '22.6', 'Adipocytes': '25.4', 'Melanocytes': '-0.163', 'Fibroblasts': '37.0', 'Peritubular cells': '0.419', 'Endometrial stromal cells': '26.3', 'Ovarian stromal cells': '12.8', 'Undifferentiated cells': '3.9', 'T-cells': '20.7', 'B-cells': '19.5', 'Plasma cells': '34.6', 'Nk-cells': '15.1', 'Granulocytes': '432.5', 'Monocytes': '333.9', 'Macrophages': '72.8', 'Hofbauer cells': '32.8', 'Kupffer cells': '75.7', 'Dendritic cells': '28.2', 'Langerhans cells': '-0.170', 'Erythroid cells': '-0.003', 'Adipocytes (Subcutaneous)': '0.110', 'Adipocytes (Visceral)': '-0.036', 'Breast glandular cells (progenitors)': '-0.236', 'Adipocytes (Breast)': '0.189', 'Colon enterocytes': '-0.125', 'Colon enteroendocrine cells': '0.283', 'Enteric glia cells': '0.170', 'Mitotic cells (Colon)': '0.110', 'Mitotic cells (Heart)': '0.495', 'Podocytes': '0.217', 'Ascending Loop of Henle cells': '0.235', 'Intercalated cells': '0.171', 'Cholangiocyte': '0.253', 'NK-cells (Liver)': '-0.088', 'Respiratory ciliated cells': '-0.149', 'Mitotic cells (Lung)': '-0.010', 'NK-cells (Lung)': '-0.006', 'B-cells (Lung)': '0.003', 'Alpha cells': '0.356', 'Beta cells': '0.160', 'Prostate glandular cells': '-0.526', 'Prostate basal glandular cells': '-0.073', 'Urothelial cells': '0.142', 'Keratinocyte (other)': '-0.395', 'Keratinocyte (granular)': '-0.256', 'Hair cortex cells': '0.159', 'Inner root sheath cells': '0.236', 'Outer root sheath cells': '0.207', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.422', 'Adipocytes (Skin)': '0.346', 'Mitotic cells (Skin)': '0.052', 'Parietal cells': '-0.588', 'Chief cells': '-0.438', 'Gastric mucous cells': '-0.289', 'Gastric enteroendocrine cells': '-0.260', 'Mitotic cells (Stomach)': '0.080', 'Parafollicular cells': '0.073', 'Thyroid glandular cells': '0.124', 'Mitotic cells (Thyroid)': '0.175', 'Adrenal cortex cells': '0.470', 'Adrenal medulla cells': '0.099', 'Mitotic cells (Adrenal gland)': '0.326', 'Minor salivary glandular cells': '0.494', 'Minor salivary gland ductal cells': '0.273', 'Minor salivary gland basal cells': '0.347', 'Mitotic cells (Minor salivary gland)': '0.287', 'Adipocytes (Minor salivary gland)': '0.382', 'Somatotropes': '-0.125', 'Lactotropes': '-0.267', 'Gonadotropes': '-0.205', 'Corticotropes': '-0.184', 'Thyrotropes': '0.010', 'Undifferentiated cells (Pituitary gland)': '0.259', 'Mitotic cells (Spleen)': '-0.026', 'Platelets': '0.007', 'Erythrocytes': '-0.115', 'Hematopoietic stem cells': '-0.047', 'B-cells (Spleen)': '0.091', 'NK-cells (Spleen)': '0.136', 'Amygdala excitatory': '129.5', 'Cerebellar inhibitory': '117.0', 'Cge interneuron': '106.5', 'Deep-layer corticothalamic and 6b': '92.5', 'Deep-layer intratelencephalic': '101.2', 'Deep-layer near-projecting': '104.7', 'Eccentric medium spiny neuron': '114.6', 'Hippocampal ca1-3': '136.2', 'Hippocampal ca4': '164.1', 'Hippocampal dentate gyrus': '116.5', 'Lamp5-lhx6 and chandelier': '120.2', 'Lower rhombic lip': '139.1', 'Mammillary body': '160.3', 'Medium spiny neuron': '103.1', 'Mge interneuron': '124.6', 'Midbrain-derived inhibitory': '185.1', 'Miscellaneous': '103.3', 'Splatter': '136.8', 'Thalamic excitatory': '157.6', 'Upper rhombic lip': '83.5', 'Upper-layer intratelencephalic': '86.3', 'Astrocyte': '50.0', 'Bergmann glia': '46.4', 'Central nervous system macrophage': '215.3', 'Choroid plexus epithelial cell': '89.3', 'Committed oligodendrocyte precursor': '153.3', 'Ependymal cell': '47.6', 'Oligodendrocyte': '169.8', 'Oligodendrocyte precursor cell': '122.8', 'Endothelial cell': '98.7', 'Pericyte': '64.2', 'Vascular associated smooth muscle cell': '53.8', 'Fibroblast': '76.4', 'Leukocyte': '125.1', 'Basophil': '132.2', 'Eosinophil': '34.7', 'Neutrophil': '303.8', 'Classical monocyte': '69.4', 'Non-classical monocyte': '116.2', 'Intermediate monocyte': '78.6', 'T-reg': '23.9', 'GdT-cell': '4.2', 'MAIT T-cell': '20.5', 'Memory CD4 T-cell': '3.9', 'Naive CD4 T-cell': '24.6', 'Memory CD8 T-cell': '3.4', 'Naive CD8 T-cell': '22.7', 'Memory B-cell': '3.1', 'Naive B-cell': '28.9', 'Plasmacytoid DC': '57.2', 'Myeloid DC': '56.0', 'NK-cell': '31.1', 'Total PBMC': '40.5', 'Vd2 gdTCR': '24.2', 'Memory CD4 T-cell Th1\\/Th17': '32.8', 'Memory CD4 T-cell Th17': '27.8', 'Memory CD4 T-cell Th2': '32.6', 'Non-Vd2 gdTCR': '32.1', 'Memory CD4 T-cell Th1': '27.5', 'Memory CD4 T-cell TFH': '25.4', 'Terminal effector memory CD4 T-cell': '52.8', 'Central memory CD8 T-cell': '31.0', 'Effector memory CD8 T-cell': '39.9', 'Terminal effector memory CD8 T-cell': '32.8', 'Non-switched memory B-cell': '33.3', 'Plasmablast': '47.4', 'Switched memory B-cell': '33.2', 'Exhausted memory B-cell': '32.2', 'Progenitor cell': '54.1', 'Memory T-reg': '43.4', 'Naive CD4 T-cell activated': '208.8', 'Naive CD8 T-cell activated': '154.6', 'Naive T-reg': '30.9'}
| null |
{'Adipose Tissue': 43.47648837209302, 'Adrenal Gland': 41.64128682170542, 'Bladder': 21.34857142857143, 'Blood': 35.72670484391819, 'Blood Vessel': 29.740427715355803, 'Brain': 14.093446328538985, 'Breast': 30.186877995642703, 'Cervix Uteri': 22.427894736842106, 'Colon': 16.37151861360719, 'Esophagus': 17.04523529411765, 'Fallopian Tube': 23.694444444444443, 'Heart': 12.735275029036004, 'Kidney': 31.939977528089887, 'Liver': 6.187169911504425, 'Lung': 52.61717993079585, 'Muscle': 32.409332503113326, 'Nerve': 16.5083295638126, 'Ovary': 25.55982777777778, 'Pancreas': 4.445531707317073, 'Pituitary': 16.24580212014134, 'Prostate': 16.351355102040817, 'Salivary Gland': 15.142135802469134, 'Skin': 24.68635212824765, 'Small Intestine': 15.957850267379678, 'Spleen': 18.22434854771784, 'Stomach': 16.169596100278554, 'Testis': 27.99499445983379, 'Thyroid': 19.344137825421132, 'Uterus': 21.459929577464788, 'Vagina': 19.098826923076924}
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[31.79, 31.49, 40.07, 42.44, 42.94, 55.2, 56.9, 52.47, 59.15, 64.03, 66.61, 68.93, 73.12, 72.72, 69.66, 70.54, 75.76, 74.52, 71.54, 71.93, 77.39, 70.72, 70.56, 74.9, 77.54, 74.2, 75.84, 77.31, 77.78, 80.47, 77.44, 79.2, 80.86, 76.01, 78.19, 79.86, 83.79, 85.1, 84.02, 85.65, 89.33, 89.15, 88.71, 89.7, 94.48, 96.94, 97.57, 98.06, 97.18, 97.31, 96.31, 94.98, 91.22, 91.15, 87.18, 90.1, 95.29, 97.14, 98.33, 98.21, 97.92, 97.17, 94.27, 95.55, 95.92, 95.35, 95.17, 97.44, 96.82, 95.92, 95.99, 93.31, 95.31, 94.26, 94.28, 97.16, 97.74, 98.68, 98.69, 98.48, 98.6, 98.24, 98.27, 98.31, 98.4, 98.32, 98.55, 98.2, 98.07, 98.45, 97.94, 98.29, 98.41, 98.54, 98.47, 98.71, 98.6, 98.06, 96.89, 95.42, 93.7, 94.8, 94.01, 91.82, 91.24, 90.28, 84.99, 85.11, 80.07, 77.09, 78.66, 77.74, 77.48, 81.95, 83.55, 88.16, 92.83, 94.23, 95.79, 96.4, 96.43, 97.43, 98.24, 98.15, 98.49, 98.62, 98.73, 98.7, 98.74, 98.72, 98.73, 98.59, 98.54, 98.57, 98.63, 98.57, 98.71, 98.66, 98.57, 98.69, 98.69, 98.55, 98.3, 98.08, 97.83, 97.25, 97.86, 97.46, 97.7, 97.2, 97.27, 96.14, 98.58, 98.51, 98.68, 96.98, 97.63, 95.39, 97.02, 97.88, 98.37, 98.63, 98.67, 98.68, 98.83, 98.85, 98.8, 98.77, 98.78, 98.81, 98.71, 98.6, 98.54, 98.57, 98.53, 98.45, 98.8, 98.55, 97.9, 93.16, 88.99, 87.59, 81.0, 77.41, 74.87, 82.43, 82.05, 82.34, 87.2, 90.82, 88.92, 90.8, 94.43, 94.76, 94.78, 95.0, 94.99, 96.03, 95.78, 98.45, 98.35, 98.7, 98.0, 97.02, 95.58, 92.97, 94.06, 94.45, 91.91, 87.29, 84.5, 91.46, 88.53, 86.33, 88.71, 90.51, 89.5, 91.33, 91.77, 86.24, 91.21, 94.92, 95.17, 97.49, 97.2, 98.38, 97.83, 98.09, 95.26, 87.31, 86.15, 85.06, 89.24, 88.08, 86.95, 85.72, 86.74, 88.35, 82.43, 85.06, 85.89, 90.08, 94.2, 95.26, 96.45, 97.5, 98.47, 97.79, 97.49, 98.39, 98.47, 98.29, 98.38, 98.39, 97.91, 97.83, 95.53, 96.38, 96.65, 90.15, 88.62, 91.24, 93.07, 95.48, 96.81, 98.25, 98.51, 98.64, 98.51, 98.32, 98.7, 98.67, 98.78, 98.73, 98.35, 97.67, 92.72, 82.77, 66.39, 50.81, 47.12, 45.35, 51.88, 69.76, 79.77, 89.19, 95.21, 97.7, 98.57, 98.72, 98.74, 98.77, 98.49, 98.71, 98.71, 98.6, 98.46, 98.47, 98.38, 98.27, 97.89, 97.77, 97.75, 96.41, 96.26, 96.9, 94.31, 95.85, 97.94, 97.84, 97.68, 97.67, 98.54, 98.69, 98.77, 98.55, 98.0, 96.11, 94.3, 93.51, 97.24, 94.74, 92.88, 96.46, 94.95, 96.65, 98.28, 98.04, 98.08, 98.49, 98.46, 98.27, 98.28, 94.03, 97.76, 98.22, 98.22, 98.65, 98.51, 98.85, 98.72, 98.46, 97.28, 93.36, 88.39, 90.01, 93.79, 92.76, 91.29, 91.49, 85.23, 87.71, 85.83, 90.5, 93.07, 92.47, 90.58, 90.92, 94.53, 95.82, 95.75, 97.75, 97.34, 96.95, 98.04, 98.42, 98.17, 98.45, 98.61, 98.49, 97.34, 96.02, 91.48, 86.72, 83.79, 77.79, 82.53, 87.08, 80.35, 80.23, 86.61, 85.76, 81.74, 81.94, 87.88, 87.41, 85.7, 86.39, 88.12, 88.01, 89.77, 90.08, 92.06, 88.31, 88.58, 89.17, 89.38, 88.42, 88.31, 90.21, 89.86, 87.66, 89.21, 91.34, 90.33, 88.24, 90.51, 90.48, 87.85, 87.27, 87.53, 83.52, 81.11, 78.17, 83.02, 83.9, 86.05, 84.57, 81.77, 85.73, 87.59, 85.82, 84.59, 87.35, 91.89, 92.12, 89.37, 92.03, 93.76, 93.02, 91.87, 94.77, 95.91, 95.46, 97.39, 97.69, 96.44, 96.47, 97.11, 96.56, 93.34, 87.54, 79.7, 80.77, 79.16, 82.59, 82.0, 86.49, 84.56, 85.84, 90.04, 92.4, 92.9, 93.96, 93.48, 93.67, 94.41, 94.17, 92.85, 93.58, 94.04, 95.32, 94.7, 94.65, 94.58, 96.49, 94.62, 95.01, 95.77, 97.44, 97.94, 98.06, 95.21, 95.99, 97.74, 98.55, 97.62, 96.33, 94.94, 92.86, 90.53, 91.75, 90.47, 90.52, 91.23, 86.82, 93.45, 95.99, 96.89, 97.75, 98.59, 98.58, 98.32, 98.32, 98.61, 98.41, 98.65, 97.41, 97.89, 95.87, 95.42, 91.41, 86.89, 81.31, 81.34, 85.54, 91.62, 93.31, 94.22, 93.27, 91.44, 92.06, 93.65, 95.53, 96.22, 95.08, 95.83, 96.93, 98.3, 98.45, 98.71, 98.5, 98.15, 97.88, 98.45, 98.73, 98.52, 98.04, 97.53, 96.35, 96.01, 94.96, 94.08, 95.79, 95.29, 92.84, 96.74, 97.25, 95.34, 96.07, 98.32, 97.72, 97.51, 95.71, 94.49, 92.87, 94.65, 95.94, 97.34, 98.47, 98.53, 97.68, 95.5, 92.61, 93.52, 94.22, 95.8, 95.84, 97.59, 96.69, 95.8, 96.36, 97.1, 97.81, 98.14, 95.53, 91.59, 88.62, 84.44, 84.48, 84.02, 78.93, 78.74, 79.09, 79.79, 75.79, 76.11, 70.24, 69.35, 67.84, 75.66, 78.22, 82.06, 84.7, 89.2, 83.69, 82.52, 88.21, 90.9, 84.57, 85.31, 91.03, 87.24, 82.48, 89.09, 87.24, 92.36, 93.3, 90.03, 91.67, 94.2, 94.84, 94.21, 93.72, 88.74, 82.29, 75.05, 76.41, 81.83, 83.02, 89.7, 93.47, 96.0, 97.05, 97.12, 97.32, 95.83, 95.63, 92.93, 92.12, 90.27, 91.07, 94.51, 93.88, 92.89, 94.0, 95.2, 93.86, 93.92, 93.53, 93.01, 92.75, 90.12, 90.36, 93.4, 93.84, 93.6, 94.09, 95.53, 95.93, 94.51, 95.16, 94.04, 94.76, 96.74, 96.0, 95.72, 95.47, 95.96, 96.24, 95.12, 92.71, 94.82, 93.99, 92.9, 90.89, 89.58, 89.72, 88.3, 83.98, 84.5, 85.7, 85.14, 87.76, 84.39, 88.88, 94.05, 95.59, 95.12, 96.1, 96.66, 96.85, 97.31, 95.86, 92.89, 90.74, 90.48, 90.93, 85.88, 77.89, 76.54, 82.43, 81.61, 87.16, 84.67, 79.28, 70.76, 68.61, 75.37, 80.4, 85.73, 82.28, 87.45, 81.79, 87.35, 91.91, 88.53, 89.29, 93.11, 94.32, 92.07, 92.28, 93.58, 92.21, 91.12, 91.97, 93.34, 88.86, 75.86, 52.57, 36.08]
|
[0.84, 0.97, 0.61, 0.89, 0.57, 0.54, 0.65, 0.27, 0.43, 0.55, 0.6, 0.1, 0.53, 0.58, 0.33, 0.5, 0.53, 0.62, 0.16, 0.61, 0.49, 0.31, 0.27, 0.6, 0.68, 0.38, 0.33, 0.63, 0.5, 0.15, 0.33, 0.75, 0.8, 0.28, 0.58, 0.01, 0.72, 0.65, 0.46, 0.19, 0.57, 0.3, 0.25, 0.84, 0.35, 0.56, 0.03, 0.02, 0.5, 0.39, 0.3, 0.44, 0.96, 0.77, 0.75, 0.38, 0.15, 0.16, 0.16, 0.16, 0.03, 0.35, 0.57, 0.35, 0.26, 0.93, 0.66, 0.22, 0.11, 0.4, 0.49, 0.53, 0.15, 0.89, 0.63, 0.03, 0.29, 0.0, 0.0, 0.03, 0.38, 0.06, 0.01, 0.31, 0.29, 0.0, 0.1, 0.82, 0.77, 0.1, 0.09, 0.86, 0.49, 0.4, 0.0, 0.0, 0.0, 0.43, 0.11, 0.35, 0.55, 0.58, 0.35, 0.63, 0.4, 0.71, 0.45, 0.81, 0.26, 0.98, 0.71, 0.59, 0.59, 0.54, 0.39, 0.6, 0.14, 0.14, 0.25, 0.15, 0.15, 0.7, 0.13, 0.62, 0.27, 0.2, 0.24, 0.0, 0.46, 0.35, 0.01, 0.2, 0.62, 0.2, 0.0, 0.22, 0.16, 0.0, 0.0, 0.04, 0.0, 0.0, 0.3, 0.43, 0.21, 0.41, 0.01, 0.65, 0.45, 0.62, 0.47, 0.14, 0.0, 0.0, 0.0, 0.0, 0.06, 0.39, 0.17, 0.26, 0.0, 0.17, 0.01, 0.0, 0.0, 0.0, 0.0, 0.03, 0.0, 0.01, 0.0, 0.07, 0.05, 0.03, 0.01, 0.06, 0.0, 0.0, 0.0, 0.0, 0.05, 0.15, 0.29, 0.09, 0.58, 0.42, 0.84, 0.21, 0.03, 0.14, 0.25, 0.0, 0.0, 0.32, 0.22, 0.03, 0.58, 0.0, 0.24, 0.05, 0.0, 0.01, 0.0, 0.04, 0.04, 0.66, 0.04, 0.0, 0.46, 0.69, 0.32, 0.0, 0.31, 0.53, 0.01, 0.05, 0.73, 0.48, 0.1, 0.84, 0.17, 0.08, 0.64, 0.11, 0.0, 0.0, 0.1, 0.07, 0.26, 0.85, 0.55, 0.89, 0.15, 0.55, 0.55, 0.82, 0.56, 0.12, 0.32, 0.96, 0.84, 0.19, 0.5, 0.07, 0.21, 0.18, 0.02, 0.54, 0.37, 0.01, 0.12, 0.49, 0.31, 0.0, 0.41, 0.39, 0.79, 0.74, 0.16, 0.47, 0.7, 0.54, 0.91, 0.28, 0.46, 0.43, 0.09, 0.49, 0.32, 0.64, 0.13, 0.23, 0.01, 0.0, 0.02, 0.0, 0.01, 0.16, 0.29, 0.17, 0.46, 0.63, 0.61, 0.77, 0.1, 0.2, 0.02, 0.0, 0.19, 0.0, 0.17, 0.01, 0.13, 0.04, 0.01, 0.04, 0.0, 0.0, 0.04, 0.07, 0.0, 0.14, 0.09, 0.55, 0.06, 0.16, 0.5, 0.81, 0.12, 0.11, 0.43, 0.92, 0.05, 0.06, 0.03, 0.0, 0.0, 0.04, 0.13, 0.34, 0.01, 0.01, 0.18, 0.03, 0.2, 0.0, 0.0, 0.03, 0.15, 0.0, 0.02, 0.07, 0.04, 0.02, 0.05, 0.22, 0.03, 0.01, 0.33, 0.0, 0.0, 0.06, 0.1, 0.35, 0.38, 0.37, 0.08, 0.07, 0.27, 0.41, 0.57, 0.14, 0.48, 0.37, 0.04, 0.34, 0.96, 0.97, 0.22, 0.59, 0.0, 0.02, 0.0, 0.28, 0.32, 0.06, 0.52, 0.0, 0.14, 0.06, 0.03, 0.01, 0.02, 0.1, 0.02, 0.22, 0.1, 0.0, 0.07, 0.43, 0.15, 0.17, 0.28, 0.47, 0.04, 0.27, 0.29, 0.4, 0.04, 0.52, 0.66, 0.39, 0.56, 0.56, 0.53, 0.47, 0.37, 0.23, 0.26, 0.11, 0.64, 0.21, 0.01, 0.21, 0.45, 0.28, 0.03, 0.14, 0.49, 0.12, 0.1, 0.61, 0.5, 0.28, 0.22, 0.32, 0.06, 0.34, 0.2, 0.04, 0.12, 0.62, 0.75, 0.34, 0.0, 0.59, 0.83, 0.09, 0.24, 0.45, 0.27, 0.03, 0.17, 0.37, 0.5, 0.1, 0.35, 0.03, 0.01, 0.22, 0.04, 0.1, 0.25, 0.38, 0.79, 0.06, 0.14, 0.38, 0.48, 0.0, 0.0, 0.36, 0.01, 0.0, 0.05, 0.01, 0.0, 0.02, 0.24, 0.01, 0.13, 0.02, 0.01, 0.06, 0.23, 0.09, 0.57, 0.16, 0.1, 0.08, 0.0, 0.0, 0.13, 0.14, 0.0, 0.0, 0.06, 0.01, 0.18, 0.26, 0.18, 0.06, 0.34, 0.39, 0.25, 0.24, 0.12, 0.05, 0.03, 0.04, 0.0, 0.0, 0.05, 0.01, 0.0, 0.06, 0.0, 0.33, 0.1, 0.53, 0.45, 0.13, 0.85, 0.66, 0.14, 0.51, 0.09, 0.29, 0.26, 0.72, 0.16, 0.92, 0.97, 0.13, 0.21, 0.29, 0.0, 0.06, 0.0, 0.02, 0.0, 0.0, 0.1, 0.41, 0.0, 0.02, 0.0, 0.29, 0.0, 0.03, 0.22, 0.62, 0.35, 0.84, 0.83, 0.19, 0.18, 0.69, 0.7, 0.14, 0.08, 0.46, 0.59, 0.36, 0.99, 0.87, 0.63, 0.23, 0.28, 0.04, 0.02, 0.23, 0.08, 0.19, 0.11, 0.0, 0.0, 0.18, 0.01, 0.22, 0.74, 0.16, 0.0, 0.01, 0.0, 0.3, 0.32, 0.24, 0.15, 0.39, 0.28, 0.69, 0.2, 0.13, 0.14, 0.47, 0.03, 0.67, 0.66, 0.34, 0.36, 0.33, 0.0, 0.1, 0.05, 0.37, 0.43, 0.01, 0.11, 0.39, 0.13, 0.0, 0.25, 0.22, 0.04, 0.41, 0.1, 0.01, 0.37, 0.13, 0.02, 0.02, 0.01, 0.13, 0.12, 0.34, 0.54, 0.69, 0.21, 0.61, 0.2, 0.0, 0.0, 0.0, 0.0, 0.0, 0.09, 0.04, 0.19, 0.53, 0.71, 0.41, 0.0, 0.28, 0.55, 0.18, 0.01, 0.66, 0.72, 0.53, 0.69, 0.15, 0.9, 0.73, 0.55, 0.2, 0.5, 0.45, 0.05, 0.0, 0.42, 0.29, 0.66, 0.5, 0.0, 0.13, 0.5, 0.25, 0.01, 0.13, 0.55, 0.3, 0.0, 0.51, 0.53, 0.21, 0.0, 0.6, 0.72, 0.57, 0.83, 0.09, 0.56, 0.86, 0.31, 0.05, 0.12, 0.0, 0.41, 0.37, 0.02, 0.16, 0.0, 0.03, 0.28, 0.67, 0.63, 0.05, 0.26, 0.12, 0.76, 0.42, 0.27, 0.07, 0.01, 0.08, 0.09, 0.16, 0.33, 0.44, 0.22, 0.22, 0.19, 0.46, 0.36, 0.0, 0.45, 0.52, 0.65, 0.04, 0.48, 0.8, 0.15, 0.02, 0.52, 0.52, 0.03, 0.11, 0.68, 0.7, 0.98]
| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 90.955992
| 0.279044
| 971
|
O60260
|
O60883
|
18241051
|
UbiNet, UbiBrowser
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
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Tissue enhanced (skeletal muscle, tongue)
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{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
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1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
|
{}
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GPR37L1
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MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYVPEEWAEYPRPIHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGTLDSCIMKPSASLPESLYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKSECRASKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTEVSSSIYFHKPRESPPLLPLGTPC
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Homo sapiens
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Cell membrane, Cell projection, cilium membrane
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Tissue enriched (brain)
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{'Ciliated cells': '0.9', 'Basal respiratory cells': '0.8', 'Club cells': '0.4', 'Ionocytes': '0.4', 'Mucus glandular cells': '0.4', 'Serous glandular cells': '0.1', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.8', 'Paneth cells': '1.5', 'Distal enterocytes': '4.7', 'Intestinal goblet cells': '1.2', 'Exocrine glandular cells': '-0.314', 'Basal prostatic cells': '0.4', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.479', 'Breast myoepithelial cells': '0.492', 'Glandular and luminal cells': '0.5', 'Secretory cells': '1.2', 'Basal keratinocytes': '0.2', 'Suprabasal keratinocytes': '0.1', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.037', 'Alveolar cells type 2': '0.071', 'Salivary duct cells': '0.1', 'Ductal cells': '0.517', 'Hepatocytes': '0.054', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.165', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.206', 'Sertoli cells': '0.008', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '0.2', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.048', 'Excitatory neurons': '0.4', 'Inhibitory neurons': '0.4', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '3.8', 'Bipolar cells': '0.9', 'Horizontal cells': '0.6', 'Astrocytes': '87.0', 'Oligodendrocyte precursor cells': '83.5', 'Oligodendrocytes': '19.0', 'Microglial cells': '2.7', 'Muller glia cells': '55.9', 'Schwann cells': '0.284', 'Spermatogonia': '-0.004', 'Spermatocytes': '-0.125', 'Early spermatids': '-0.123', 'Late spermatids': '0.061', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.1', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '1.3', 'Endothelial cells': '0.3', 'Lymphatic endothelial cells': '0.1', 'Cardiomyocytes': '0.187', 'Skeletal myocytes': '0.064', 'Smooth muscle cells': '0.0', 'Adipocytes': '0.0', 'Melanocytes': '-0.003', 'Fibroblasts': '0.2', 'Peritubular cells': '-0.046', 'Endometrial stromal cells': '0.1', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '0.4', 'T-cells': '0.1', 'B-cells': '0.0', 'Plasma cells': '0.1', 'Nk-cells': '0.1', 'Granulocytes': '0.1', 'Monocytes': '0.0', 'Macrophages': '0.1', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.080', 'Erythroid cells': '0.140', 'Adipocytes (Subcutaneous)': '-0.206', 'Adipocytes (Visceral)': '-0.147', 'Breast glandular cells (progenitors)': '0.428', 'Adipocytes (Breast)': '-0.461', 'Colon enterocytes': '-0.110', 'Colon enteroendocrine cells': '0.399', 'Enteric glia cells': '0.678', 'Mitotic cells (Colon)': '-0.230', 'Mitotic cells (Heart)': '0.202', 'Podocytes': '-0.121', 'Ascending Loop of Henle cells': '0.367', 'Intercalated cells': '-0.069', 'Cholangiocyte': '0.213', 'NK-cells (Liver)': '-0.258', 'Respiratory ciliated cells': '0.202', 'Mitotic cells (Lung)': '-0.042', 'NK-cells (Lung)': '0.035', 'B-cells (Lung)': '-0.012', 'Alpha cells': '0.166', 'Beta cells': '0.130', 'Prostate glandular cells': '-0.045', 'Prostate basal glandular cells': '-0.294', 'Urothelial cells': '-0.221', 'Keratinocyte (other)': '-0.038', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.128', 'Inner root sheath cells': '0.114', 'Outer root sheath cells': '0.292', 'Sebaceous gland cells': '0.101', 'Eccrine sweat gland cells': '0.309', 'Adipocytes (Skin)': '0.088', 'Mitotic cells (Skin)': '0.149', 'Parietal cells': '-0.684', 'Chief cells': '-0.617', 'Gastric mucous cells': '-0.528', 'Gastric enteroendocrine cells': '-0.515', 'Mitotic cells (Stomach)': '-0.154', 'Parafollicular cells': '0.118', 'Thyroid glandular cells': '0.452', 'Mitotic cells (Thyroid)': '-0.024', 'Adrenal cortex cells': '0.289', 'Adrenal medulla cells': '0.174', 'Mitotic cells (Adrenal gland)': '0.146', 'Minor salivary glandular cells': '0.170', 'Minor salivary gland ductal cells': '0.178', 'Minor salivary gland basal cells': '0.140', 'Mitotic cells (Minor salivary gland)': '0.101', 'Adipocytes (Minor salivary gland)': '0.100', 'Somatotropes': '-0.435', 'Lactotropes': '-0.418', 'Gonadotropes': '-0.005', 'Corticotropes': '-0.155', 'Thyrotropes': '-0.065', 'Undifferentiated cells (Pituitary gland)': '0.616', 'Mitotic cells (Spleen)': '-0.013', 'Platelets': '0.075', 'Erythrocytes': '0.168', 'Hematopoietic stem cells': '0.077', 'B-cells (Spleen)': '0.058', 'NK-cells (Spleen)': '0.108', 'Amygdala excitatory': '0.4', 'Cerebellar inhibitory': '1.4', 'Cge interneuron': '0.6', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.3', 'Deep-layer near-projecting': '0.3', 'Eccentric medium spiny neuron': '0.4', 'Hippocampal ca1-3': '0.2', 'Hippocampal ca4': '0.1', 'Hippocampal dentate gyrus': '1.3', 'Lamp5-lhx6 and chandelier': '0.3', 'Lower rhombic lip': '0.4', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.5', 'Mge interneuron': '0.4', 'Midbrain-derived inhibitory': '0.4', 'Miscellaneous': '0.4', 'Splatter': '0.7', 'Thalamic excitatory': '0.3', 'Upper rhombic lip': '2.1', 'Upper-layer intratelencephalic': '0.4', 'Astrocyte': '161.2', 'Bergmann glia': '238.4', 'Central nervous system macrophage': '2.8', 'Choroid plexus epithelial cell': '3.1', 'Committed oligodendrocyte precursor': '63.0', 'Ependymal cell': '67.9', 'Oligodendrocyte': '38.0', 'Oligodendrocyte precursor cell': '211.6', 'Endothelial cell': '2.7', 'Pericyte': '2.1', 'Vascular associated smooth muscle cell': '3.2', 'Fibroblast': '2.4', 'Leukocyte': '3.2', 'Basophil': '3.3', 'Eosinophil': '0.2', 'Neutrophil': '4.3', 'Classical monocyte': '0.5', 'Non-classical monocyte': '0.5', 'Intermediate monocyte': '1.3', 'T-reg': '1.6', 'GdT-cell': '0.1', 'MAIT T-cell': '1.2', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.3', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.1', 'Naive B-cell': '0.2', 'Plasmacytoid DC': '1.3', 'Myeloid DC': '0.9', 'NK-cell': '0.4', 'Total PBMC': '0.9', 'Vd2 gdTCR': '1.1', 'Memory CD4 T-cell Th1\\/Th17': '0.4', 'Memory CD4 T-cell Th17': '0.5', 'Memory CD4 T-cell Th2': '0.5', 'Non-Vd2 gdTCR': '1.5', 'Memory CD4 T-cell Th1': '0.4', 'Memory CD4 T-cell TFH': '0.5', 'Terminal effector memory CD4 T-cell': '1.6', 'Central memory CD8 T-cell': '1.1', 'Effector memory CD8 T-cell': '1.4', 'Terminal effector memory CD8 T-cell': '1.2', 'Non-switched memory B-cell': '1.7', 'Plasmablast': '0.8', 'Switched memory B-cell': '1.7', 'Exhausted memory B-cell': '2.0', 'Progenitor cell': '1.9', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.2', 'Naive CD8 T-cell activated': '0.2', 'Naive T-reg': '0.4'}
| null |
{'Adipose Tissue': 0.1861654352159468, 'Adrenal Gland': 0.3280871162790698, 'Bladder': 0.1772385714285714, 'Blood': 0.1061029558665231, 'Blood Vessel': 0.229433413483146, 'Brain': 43.8123433005299, 'Breast': 0.2083804422657952, 'Cervix Uteri': 0.5468226315789474, 'Colon': 1.4540545186136071, 'Esophagus': 0.7768902698961938, 'Fallopian Tube': 0.3950666666666667, 'Heart': 0.1211370662020906, 'Kidney': 0.0649462921348314, 'Liver': 0.2069027831858407, 'Lung': 0.1368281020761245, 'Muscle': 0.0712870834371108, 'Nerve': 42.20858804523425, 'Ovary': 0.1984038944444444, 'Pancreas': 0.0601109725609756, 'Pituitary': 1.413099222614841, 'Prostate': 0.6109943265306123, 'Salivary Gland': 0.2978457407407407, 'Skin': 0.1272688231066887, 'Small Intestine': 0.6549433155080214, 'Spleen': 0.0674714605809128, 'Stomach': 0.4490685543175487, 'Testis': 1.0903747922437672, 'Thyroid': 0.4744253292496171, 'Uterus': 0.2638145070422535, 'Vagina': 0.4577049358974359}
|
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| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 67.86158
| 0.531933
| 1,222
|
O60260
|
O94826
|
33082525, 23503661
|
DegPred
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
|
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
|
{}
|
TOMM70
|
MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGTGGLPRWQLALAVGAPLLLGAGAIYLWSRQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFSSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEIDAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEMEMAHLYSLCDAAHAQTEVAKKYGLKPPTL
|
Homo sapiens
|
Mitochondrion outer membrane
|
Low tissue specificity
|
{'Ciliated cells': '16.5', 'Basal respiratory cells': '20.8', 'Club cells': '23.2', 'Ionocytes': '13.6', 'Mucus glandular cells': '23.9', 'Serous glandular cells': '22.6', 'Gastric mucus-secreting cells': '20.0', 'Proximal enterocytes': '25.2', 'Paneth cells': '16.4', 'Distal enterocytes': '25.6', 'Intestinal goblet cells': '29.1', 'Exocrine glandular cells': '-0.572', 'Basal prostatic cells': '25.7', 'Prostatic glandular cells': '24.7', 'Breast glandular cells': '0.086', 'Breast myoepithelial cells': '0.107', 'Glandular and luminal cells': '26.7', 'Secretory cells': '26.1', 'Basal keratinocytes': '33.6', 'Suprabasal keratinocytes': '51.6', 'Basal squamous epithelial cells': '28.8', 'Squamous epithelial cells': '48.4', 'Alveolar cells type 1': '-0.028', 'Alveolar cells type 2': '0.066', 'Salivary duct cells': '22.1', 'Ductal cells': '0.398', 'Hepatocytes': '0.412', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.405', 'Distal tubular cells': '9.2', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.166', 'Sertoli cells': '0.184', 'Granulosa cells': '24.0', 'Enteroendocrine cells': '30.9', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.239', 'Excitatory neurons': '34.8', 'Inhibitory neurons': '33.6', 'Cone photoreceptor cells': '40.8', 'Rod photoreceptor cells': '26.8', 'Bipolar cells': '24.3', 'Horizontal cells': '16.4', 'Astrocytes': '15.2', 'Oligodendrocyte precursor cells': '23.6', 'Oligodendrocytes': '25.6', 'Microglial cells': '17.0', 'Muller glia cells': '13.4', 'Schwann cells': '0.083', 'Spermatogonia': '0.537', 'Spermatocytes': '0.671', 'Early spermatids': '0.294', 'Late spermatids': '-0.205', 'Oocytes': '34.6', 'Cytotrophoblasts': '27.7', 'Syncytiotrophoblasts': '15.0', 'Extravillous trophoblasts': '33.7', 'Endothelial cells': '21.4', 'Lymphatic endothelial cells': '20.4', 'Cardiomyocytes': '0.693', 'Skeletal myocytes': '-0.103', 'Smooth muscle cells': '25.1', 'Adipocytes': '23.7', 'Melanocytes': '0.171', 'Fibroblasts': '26.1', 'Peritubular cells': '0.198', 'Endometrial stromal cells': '34.8', 'Ovarian stromal cells': '24.3', 'Undifferentiated cells': '39.0', 'T-cells': '22.0', 'B-cells': '20.9', 'Plasma cells': '31.8', 'Nk-cells': '18.1', 'Granulocytes': '28.7', 'Monocytes': '15.0', 'Macrophages': '19.1', 'Hofbauer cells': '21.2', 'Kupffer cells': '21.2', 'Dendritic cells': '11.3', 'Langerhans cells': '0.345', 'Erythroid cells': '-0.042', 'Adipocytes (Subcutaneous)': '0.385', 'Adipocytes (Visceral)': '0.146', 'Breast glandular cells (progenitors)': '0.058', 'Adipocytes (Breast)': '0.144', 'Colon enterocytes': '-0.156', 'Colon enteroendocrine cells': '0.224', 'Enteric glia cells': '-0.216', 'Mitotic cells (Colon)': '-0.154', 'Mitotic cells (Heart)': '0.474', 'Podocytes': '0.013', 'Ascending Loop of Henle cells': '0.393', 'Intercalated cells': '0.097', 'Cholangiocyte': '0.236', 'NK-cells (Liver)': '-0.279', 'Respiratory ciliated cells': '0.004', 'Mitotic cells (Lung)': '0.124', 'NK-cells (Lung)': '-0.150', 'B-cells (Lung)': '-0.171', 'Alpha cells': '0.321', 'Beta cells': '0.164', 'Prostate glandular cells': '-0.177', 'Prostate basal glandular cells': '0.012', 'Urothelial cells': '-0.058', 'Keratinocyte (other)': '0.340', 'Keratinocyte (granular)': '-0.130', 'Hair cortex cells': '-0.115', 'Inner root sheath cells': '-0.014', 'Outer root sheath cells': '0.103', 'Sebaceous gland cells': '0.267', 'Eccrine sweat gland cells': '-0.076', 'Adipocytes (Skin)': '-0.150', 'Mitotic cells (Skin)': '0.361', 'Parietal cells': '-0.588', 'Chief cells': '-0.399', 'Gastric mucous cells': '-0.461', 'Gastric enteroendocrine cells': '-0.389', 'Mitotic cells (Stomach)': '0.001', 'Parafollicular cells': '0.104', 'Thyroid glandular cells': '0.502', 'Mitotic cells (Thyroid)': '-0.034', 'Adrenal cortex cells': '0.531', 'Adrenal medulla cells': '0.064', 'Mitotic cells (Adrenal gland)': '0.394', 'Minor salivary glandular cells': '0.211', 'Minor salivary gland ductal cells': '-0.198', 'Minor salivary gland basal cells': '0.625', 'Mitotic cells (Minor salivary gland)': '0.678', 'Adipocytes (Minor salivary gland)': '0.269', 'Somatotropes': '0.200', 'Lactotropes': '0.215', 'Gonadotropes': '0.112', 'Corticotropes': '0.003', 'Thyrotropes': '0.247', 'Undifferentiated cells (Pituitary gland)': '-0.002', 'Mitotic cells (Spleen)': '-0.024', 'Platelets': '-0.159', 'Erythrocytes': '-0.163', 'Hematopoietic stem cells': '-0.257', 'B-cells (Spleen)': '0.284', 'NK-cells (Spleen)': '0.204', 'Amygdala excitatory': '56.5', 'Cerebellar inhibitory': '56.5', 'Cge interneuron': '53.4', 'Deep-layer corticothalamic and 6b': '62.9', 'Deep-layer intratelencephalic': '57.0', 'Deep-layer near-projecting': '60.4', 'Eccentric medium spiny neuron': '120.7', 'Hippocampal ca1-3': '52.5', 'Hippocampal ca4': '63.5', 'Hippocampal dentate gyrus': '65.6', 'Lamp5-lhx6 and chandelier': '59.6', 'Lower rhombic lip': '56.3', 'Mammillary body': '56.9', 'Medium spiny neuron': '212.5', 'Mge interneuron': '54.0', 'Midbrain-derived inhibitory': '54.9', 'Miscellaneous': '53.4', 'Splatter': '54.3', 'Thalamic excitatory': '54.8', 'Upper rhombic lip': '55.2', 'Upper-layer intratelencephalic': '48.5', 'Astrocyte': '29.8', 'Bergmann glia': '40.8', 'Central nervous system macrophage': '40.2', 'Choroid plexus epithelial cell': '58.8', 'Committed oligodendrocyte precursor': '39.4', 'Ependymal cell': '26.1', 'Oligodendrocyte': '38.8', 'Oligodendrocyte precursor cell': '46.5', 'Endothelial cell': '35.5', 'Pericyte': '39.1', 'Vascular associated smooth muscle cell': '31.2', 'Fibroblast': '40.6', 'Leukocyte': '39.0', 'Basophil': '6.9', 'Eosinophil': '1.2', 'Neutrophil': '1.2', 'Classical monocyte': '20.1', 'Non-classical monocyte': '35.5', 'Intermediate monocyte': '10.5', 'T-reg': '14.5', 'GdT-cell': '1.9', 'MAIT T-cell': '18.5', 'Memory CD4 T-cell': '2.3', 'Naive CD4 T-cell': '66.4', 'Memory CD8 T-cell': '2.0', 'Naive CD8 T-cell': '59.0', 'Memory B-cell': '2.0', 'Naive B-cell': '46.8', 'Plasmacytoid DC': '10.2', 'Myeloid DC': '14.9', 'NK-cell': '39.1', 'Total PBMC': '12.1', 'Vd2 gdTCR': '15.3', 'Memory CD4 T-cell Th1\\/Th17': '57.6', 'Memory CD4 T-cell Th17': '51.1', 'Memory CD4 T-cell Th2': '52.7', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '45.0', 'Memory CD4 T-cell TFH': '40.9', 'Terminal effector memory CD4 T-cell': '13.2', 'Central memory CD8 T-cell': '17.1', 'Effector memory CD8 T-cell': '11.4', 'Terminal effector memory CD8 T-cell': '13.7', 'Non-switched memory B-cell': '13.1', 'Plasmablast': '23.8', 'Switched memory B-cell': '15.7', 'Exhausted memory B-cell': '14.3', 'Progenitor cell': '13.4', 'Memory T-reg': '37.8', 'Naive CD4 T-cell activated': '124.7', 'Naive CD8 T-cell activated': '126.6', 'Naive T-reg': '63.0'}
|
7DHG, 7KDT
|
{'Adipose Tissue': 40.40759468438538, 'Adrenal Gland': 30.652131782945737, 'Bladder': 51.667142857142856, 'Blood': 17.596816038751346, 'Blood Vessel': 48.92008988764045, 'Brain': 38.90177668433005, 'Breast': 39.87202614379085, 'Cervix Uteri': 46.33105263157895, 'Colon': 41.77775353016688, 'Esophagus': 40.283602076124566, 'Fallopian Tube': 45.434444444444445, 'Heart': 23.242494076655053, 'Kidney': 21.13713483146067, 'Liver': 28.742491150442476, 'Lung': 28.980185121107265, 'Muscle': 52.39267745952677, 'Nerve': 41.05665589660743, 'Ovary': 46.76905555555556, 'Pancreas': 17.265771341463413, 'Pituitary': 33.67681978798587, 'Prostate': 33.383265306122446, 'Salivary Gland': 31.153395061728396, 'Skin': 41.14071862907684, 'Small Intestine': 30.28497326203209, 'Spleen': 23.338672199170123, 'Stomach': 29.46537883008357, 'Testis': 32.40667590027701, 'Thyroid': 39.78052067381317, 'Uterus': 50.30922535211267, 'Vagina': 41.820641025641024}
|
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[0.67, 0.36, 0.63, 0.2, 0.42, 0.32, 0.13, 0.18, 0.32, 0.15, 0.12, 0.12, 0.24, 0.23, 0.2, 0.4, 0.65, 0.62, 0.74, 0.43, 0.48, 0.93, 0.67, 1.0, 0.98, 1.0, 0.96, 1.0, 0.89, 0.96, 1.0, 0.94, 0.95, 1.0, 0.83, 0.75, 0.54, 0.82, 0.64, 0.42, 0.44, 0.53, 0.36, 0.29, 0.45, 0.14, 0.18, 0.37, 0.52, 0.57, 0.19, 0.36, 0.26, 0.4, 0.17, 0.48, 0.59, 0.47, 0.6, 0.28, 0.45, 0.59, 0.38, 0.61, 0.54, 0.75, 0.65, 0.67, 0.76, 0.73, 0.91, 0.62, 0.91, 1.0, 0.86, 0.95, 0.96, 0.94, 0.93, 0.91, 0.75, 0.91, 0.68, 0.87, 0.29, 0.1, 0.66, 0.31, 0.91, 0.89, 0.82, 0.92, 0.91, 0.94, 0.91, 0.97, 0.92, 0.98, 0.98, 0.97, 0.88, 0.97, 0.92, 0.69, 0.96, 0.75, 0.81, 0.56, 0.61, 0.38, 0.24, 0.46, 0.46, 0.0, 0.34, 0.5, 0.06, 0.11, 0.49, 0.49, 0.0, 0.11, 0.73, 0.3, 0.13, 0.5, 0.53, 0.32, 0.48, 0.21, 0.58, 0.4, 0.0, 0.13, 0.66, 0.05, 0.0, 0.4, 0.42, 0.0, 0.14, 0.76, 0.3, 0.08, 0.21, 0.74, 0.82, 0.46, 0.41, 0.66, 0.29, 0.11, 0.01, 0.18, 0.01, 0.17, 0.04, 0.0, 0.16, 0.0, 0.03, 0.0, 0.12, 0.24, 0.53, 0.27, 0.67, 0.41, 0.22, 0.67, 0.36, 0.0, 0.12, 0.63, 0.06, 0.0, 0.29, 0.45, 0.0, 0.05, 0.58, 0.25, 0.32, 0.41, 0.49, 0.15, 0.25, 0.48, 0.0, 0.0, 0.15, 0.14, 0.1, 0.0, 0.3, 0.0, 0.11, 0.35, 0.65, 0.33, 0.63, 0.34, 0.16, 0.7, 0.45, 0.02, 0.08, 0.23, 0.03, 0.0, 0.1, 0.0, 0.01, 0.04, 0.11, 0.29, 0.26, 0.56, 0.16, 0.69, 0.31, 0.51, 0.6, 0.01, 0.19, 0.43, 0.09, 0.07, 0.12, 0.5, 0.06, 0.13, 0.33, 0.42, 0.15, 0.0, 0.54, 0.48, 0.36, 0.0, 0.57, 0.7, 0.34, 0.25, 0.76, 0.81, 0.18, 0.91, 0.54, 0.36, 0.17, 0.09, 0.16, 0.4, 0.27, 0.2, 0.01, 0.41, 0.22, 0.1, 0.1, 0.59, 0.02, 0.06, 0.29, 0.18, 0.02, 0.27, 0.0, 0.33, 0.53, 0.8, 0.4, 0.91, 0.94, 0.68, 0.96, 0.58, 0.5, 0.7, 0.91, 0.45, 0.55, 0.94, 0.69, 0.92, 0.9, 0.78, 0.82, 0.67, 0.72, 0.61, 0.81, 0.52, 0.77, 0.08, 0.06, 0.08, 0.11, 0.38, 0.0, 0.04, 0.54, 0.19, 0.16, 0.61, 0.52, 0.41, 0.32, 0.07, 0.72, 0.4, 0.0, 0.2, 0.48, 0.1, 0.0, 0.17, 0.55, 0.05, 0.17, 0.76, 0.73, 0.8, 0.26, 0.9, 0.24, 0.26, 0.16, 0.22, 0.0, 0.04, 0.01, 0.0, 0.13, 0.0, 0.0, 0.0, 0.17, 0.15, 0.05, 0.06, 0.16, 0.3, 0.19, 0.77, 0.22, 0.0, 0.37, 0.58, 0.07, 0.0, 0.3, 0.49, 0.0, 0.19, 0.58, 0.23, 0.75, 0.99, 0.15, 0.52, 0.33, 0.35, 0.03, 0.19, 0.0, 0.04, 0.0, 0.01, 0.01, 0.01, 0.13, 0.0, 0.24, 0.01, 0.11, 0.11, 0.15, 0.42, 0.56, 0.35, 0.38, 0.85, 0.36, 0.0, 0.36, 0.53, 0.03, 0.01, 0.42, 0.35, 0.0, 0.11, 0.76, 0.4, 0.1, 0.47, 0.66, 0.02, 0.01, 0.04, 0.0, 0.1, 0.04, 0.05, 0.14, 0.0, 0.07, 0.06, 0.17, 0.19, 0.28, 0.32, 0.67, 0.38, 0.13, 0.62, 0.5, 0.0, 0.11, 0.51, 0.04, 0.01, 0.38, 0.25, 0.02, 0.19, 0.64, 0.28, 0.37, 0.51, 0.67, 0.11, 0.15, 0.19, 0.0, 0.19, 0.0, 0.09, 0.25, 0.1, 0.07, 0.0, 0.32, 0.0, 0.3, 0.31, 0.01, 0.26, 0.65, 0.69, 0.59, 0.34, 0.62, 0.7, 0.49, 0.11, 0.65, 0.57, 0.07, 0.07, 0.56, 0.13, 0.0, 0.48, 0.54, 0.03, 0.17, 0.85, 0.58, 0.13, 0.52, 0.88, 0.14, 0.08, 0.17, 0.01, 0.1, 0.03, 0.03, 0.05, 0.0, 0.11, 0.0, 0.0, 0.12, 0.3, 0.32, 0.61, 0.36, 0.15, 0.35, 0.47, 0.0, 0.15, 0.61, 0.15, 0.03, 0.38, 0.45, 0.01, 0.17, 0.66, 0.38, 0.3, 0.49, 0.63, 0.16, 0.04, 0.25, 0.06, 0.05, 0.0, 0.03, 0.09, 0.0, 0.17, 0.03, 0.05, 0.21, 0.35, 0.43, 0.69, 0.78, 0.34, 0.27, 0.73, 0.39, 0.0, 0.1, 0.54, 0.07, 0.0, 0.44, 0.44, 0.0, 0.18, 0.83, 0.34, 0.16, 0.64, 0.35, 0.07, 0.19, 0.1, 0.0, 0.11, 0.13, 0.09, 0.09, 0.0, 0.16, 0.05, 0.05, 0.09, 0.12, 0.34, 0.39, 0.32, 0.14, 0.84, 0.58, 0.0, 0.15, 0.48, 0.17, 0.01, 0.38, 0.37, 0.0, 0.0, 0.55, 0.12, 0.01, 0.13, 0.1, 0.42, 0.31, 0.24, 0.01, 0.11, 0.47, 0.03, 0.15, 0.13, 0.18, 0.04, 0.09, 0.23, 0.01, 0.43, 0.05, 0.14, 0.38, 0.59, 0.02, 0.2, 0.81, 0.72, 0.13, 0.68, 0.11, 0.94, 0.27, 0.53, 0.56, 0.44]
| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 79.955181
| 0.349671
| 1,235
|
O60260
|
O95140
|
20871098, UNIPROT, 33082525, 23503661
|
UbiNet, UbiBrowser, 31181401, DegPred
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
|
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
|
{}
|
MFN2
|
MSLLFSRCNSIVTVKKNKRHMAEVNASPLKHFVTAKKKINGIFEQLGAYIQESATFLEDTYRNAELDPVTTEEQVLDVKGYLSKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHEAFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHMERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECISQSAVKTKFEQHTVRAKQIAEAVRLIMDSLHMAAREQQVYCEEMREERQDRLKFIDKQLELLAQDYKLRIKQITEEVERQVSTAMAEEIRRLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEEGLGRNMSDRCSTAITNSLQTMQQDMIDGLKPLLPVSVRSQIDMLVPRQCFSLNYDLNCDKLCADFQEDIEFHFSLGWTMLVNRFLGPKNSRRALMGYNDQVQRPIPLTPANPSMPPLPQGSLTQEEFMVSMVTGLASLTSRTSMGILVVGGVVWKAVGWRLIALSFGLYGLLYVYERLTWTTKAKERAFKRQFVEHASEKLQLVISYTGSNCSHQVQQELSGTFAHLCQQVDVTRENLEQEIAAMNKKIEVLDSLQSKAKLLRNKAGWLDSELNMFTHQYLQPSR
|
Homo sapiens
|
Mitochondrion outer membrane
|
Tissue enhanced (heart muscle, skeletal muscle, tongue)
|
{'Ciliated cells': '11.3', 'Basal respiratory cells': '19.3', 'Club cells': '15.9', 'Ionocytes': '16.6', 'Mucus glandular cells': '19.8', 'Serous glandular cells': '11.8', 'Gastric mucus-secreting cells': '14.1', 'Proximal enterocytes': '37.5', 'Paneth cells': '15.2', 'Distal enterocytes': '40.4', 'Intestinal goblet cells': '21.8', 'Exocrine glandular cells': '-0.735', 'Basal prostatic cells': '19.0', 'Prostatic glandular cells': '11.7', 'Breast glandular cells': '0.113', 'Breast myoepithelial cells': '0.160', 'Glandular and luminal cells': '13.3', 'Secretory cells': '11.8', 'Basal keratinocytes': '30.6', 'Suprabasal keratinocytes': '30.7', 'Basal squamous epithelial cells': '22.6', 'Squamous epithelial cells': '26.1', 'Alveolar cells type 1': '0.265', 'Alveolar cells type 2': '0.194', 'Salivary duct cells': '22.9', 'Ductal cells': '0.672', 'Hepatocytes': '0.429', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '6.1', 'Collecting duct cells': '9.7', 'Mesothelial cells': '0.022', 'Sertoli cells': '0.369', 'Granulosa cells': '11.5', 'Enteroendocrine cells': '22.6', 'Pancreatic endocrine cells': '13.6', 'Leydig cells': '0.275', 'Excitatory neurons': '20.8', 'Inhibitory neurons': '23.5', 'Cone photoreceptor cells': '17.0', 'Rod photoreceptor cells': '23.6', 'Bipolar cells': '24.8', 'Horizontal cells': '33.4', 'Astrocytes': '15.8', 'Oligodendrocyte precursor cells': '10.4', 'Oligodendrocytes': '15.5', 'Microglial cells': '8.1', 'Muller glia cells': '14.6', 'Schwann cells': '0.087', 'Spermatogonia': '0.402', 'Spermatocytes': '0.495', 'Early spermatids': '0.081', 'Late spermatids': '-0.305', 'Oocytes': '24.3', 'Cytotrophoblasts': '15.8', 'Syncytiotrophoblasts': '26.9', 'Extravillous trophoblasts': '16.6', 'Endothelial cells': '16.8', 'Lymphatic endothelial cells': '14.4', 'Cardiomyocytes': '0.788', 'Skeletal myocytes': '0.334', 'Smooth muscle cells': '15.4', 'Adipocytes': '17.8', 'Melanocytes': '0.194', 'Fibroblasts': '14.2', 'Peritubular cells': '0.237', 'Endometrial stromal cells': '12.4', 'Ovarian stromal cells': '8.0', 'Undifferentiated cells': '21.8', 'T-cells': '11.9', 'B-cells': '10.3', 'Plasma cells': '12.4', 'Nk-cells': '10.8', 'Granulocytes': '17.9', 'Monocytes': '36.2', 'Macrophages': '18.5', 'Hofbauer cells': '14.8', 'Kupffer cells': '24.1', 'Dendritic cells': '10.3', 'Langerhans cells': '0.238', 'Erythroid cells': '-0.052', 'Adipocytes (Subcutaneous)': '0.235', 'Adipocytes (Visceral)': '0.357', 'Breast glandular cells (progenitors)': '0.148', 'Adipocytes (Breast)': '0.126', 'Colon enterocytes': '-0.226', 'Colon enteroendocrine cells': '0.037', 'Enteric glia cells': '-0.258', 'Mitotic cells (Colon)': '-0.276', 'Mitotic cells (Heart)': '0.427', 'Podocytes': '-0.131', 'Ascending Loop of Henle cells': '0.501', 'Intercalated cells': '0.015', 'Cholangiocyte': '0.220', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '-0.119', 'Mitotic cells (Lung)': '-0.009', 'NK-cells (Lung)': '-0.040', 'B-cells (Lung)': '-0.234', 'Alpha cells': '0.405', 'Beta cells': '0.228', 'Prostate glandular cells': '-0.251', 'Prostate basal glandular cells': '0.005', 'Urothelial cells': '-0.055', 'Keratinocyte (other)': '0.487', 'Keratinocyte (granular)': '0.090', 'Hair cortex cells': '-0.160', 'Inner root sheath cells': '-0.135', 'Outer root sheath cells': '-0.046', 'Sebaceous gland cells': '0.010', 'Eccrine sweat gland cells': '-0.321', 'Adipocytes (Skin)': '-0.319', 'Mitotic cells (Skin)': '0.235', 'Parietal cells': '-0.492', 'Chief cells': '-0.571', 'Gastric mucous cells': '-0.289', 'Gastric enteroendocrine cells': '-0.512', 'Mitotic cells (Stomach)': '0.081', 'Parafollicular cells': '0.128', 'Thyroid glandular cells': '0.451', 'Mitotic cells (Thyroid)': '-0.205', 'Adrenal cortex cells': '0.503', 'Adrenal medulla cells': '0.102', 'Mitotic cells (Adrenal gland)': '0.328', 'Minor salivary glandular cells': '0.126', 'Minor salivary gland ductal cells': '-0.236', 'Minor salivary gland basal cells': '0.636', 'Mitotic cells (Minor salivary gland)': '0.668', 'Adipocytes (Minor salivary gland)': '0.271', 'Somatotropes': '0.003', 'Lactotropes': '-0.060', 'Gonadotropes': '0.023', 'Corticotropes': '0.048', 'Thyrotropes': '0.215', 'Undifferentiated cells (Pituitary gland)': '0.190', 'Mitotic cells (Spleen)': '-0.157', 'Platelets': '0.170', 'Erythrocytes': '-0.041', 'Hematopoietic stem cells': '-0.005', 'B-cells (Spleen)': '0.128', 'NK-cells (Spleen)': '0.129', 'Amygdala excitatory': '29.8', 'Cerebellar inhibitory': '31.1', 'Cge interneuron': '32.6', 'Deep-layer corticothalamic and 6b': '28.8', 'Deep-layer intratelencephalic': '33.0', 'Deep-layer near-projecting': '25.9', 'Eccentric medium spiny neuron': '31.9', 'Hippocampal ca1-3': '30.6', 'Hippocampal ca4': '23.3', 'Hippocampal dentate gyrus': '25.0', 'Lamp5-lhx6 and chandelier': '35.1', 'Lower rhombic lip': '25.8', 'Mammillary body': '36.6', 'Medium spiny neuron': '34.9', 'Mge interneuron': '36.5', 'Midbrain-derived inhibitory': '36.3', 'Miscellaneous': '30.3', 'Splatter': '29.1', 'Thalamic excitatory': '34.8', 'Upper rhombic lip': '24.8', 'Upper-layer intratelencephalic': '29.5', 'Astrocyte': '26.2', 'Bergmann glia': '17.7', 'Central nervous system macrophage': '22.5', 'Choroid plexus epithelial cell': '24.3', 'Committed oligodendrocyte precursor': '19.2', 'Ependymal cell': '19.2', 'Oligodendrocyte': '22.6', 'Oligodendrocyte precursor cell': '18.5', 'Endothelial cell': '19.4', 'Pericyte': '28.1', 'Vascular associated smooth muscle cell': '24.7', 'Fibroblast': '15.5', 'Leukocyte': '21.7', 'Basophil': '42.4', 'Eosinophil': '7.6', 'Neutrophil': '134.1', 'Classical monocyte': '83.4', 'Non-classical monocyte': '94.4', 'Intermediate monocyte': '79.0', 'T-reg': '28.0', 'GdT-cell': '9.0', 'MAIT T-cell': '41.0', 'Memory CD4 T-cell': '6.8', 'Naive CD4 T-cell': '54.1', 'Memory CD8 T-cell': '7.9', 'Naive CD8 T-cell': '56.3', 'Memory B-cell': '6.7', 'Naive B-cell': '51.6', 'Plasmacytoid DC': '34.8', 'Myeloid DC': '36.0', 'NK-cell': '82.4', 'Total PBMC': '46.5', 'Vd2 gdTCR': '31.8', 'Memory CD4 T-cell TFH': '69.6', 'Memory CD4 T-cell Th2': '63.8', 'Memory CD4 T-cell Th17': '60.6', 'Memory CD4 T-cell Th1\\/Th17': '54.2', 'Non-Vd2 gdTCR': '48.4', 'Memory CD4 T-cell Th1': '65.0', 'Terminal effector memory CD4 T-cell': '32.7', 'Central memory CD8 T-cell': '32.6', 'Effector memory CD8 T-cell': '43.0', 'Terminal effector memory CD8 T-cell': '46.8', 'Switched memory B-cell': '35.5', 'Plasmablast': '31.2', 'Non-switched memory B-cell': '38.2', 'Exhausted memory B-cell': '34.3', 'Progenitor cell': '30.6', 'Naive CD4 T-cell activated': '94.3', 'Naive CD8 T-cell activated': '107.5', 'Memory T-reg': '77.2', 'Naive T-reg': '60.8'}
|
6JFK, 6JFL, 6JFM
|
{'Adipose Tissue': 57.64613787375415, 'Adrenal Gland': 44.217519379844965, 'Bladder': 98.48190476190476, 'Blood': 54.81893541442411, 'Blood Vessel': 65.23411235955055, 'Brain': 59.21468735806207, 'Breast': 58.895250544662304, 'Cervix Uteri': 61.53263157894736, 'Colon': 87.82132220795891, 'Esophagus': 112.32813148788928, 'Fallopian Tube': 59.60888888888889, 'Heart': 152.61600232288038, 'Kidney': 36.678561797752806, 'Liver': 40.75743362831859, 'Lung': 64.84076124567474, 'Muscle': 160.17819427148194, 'Nerve': 63.30634894991922, 'Ovary': 58.32266666666666, 'Pancreas': 15.422475609756098, 'Pituitary': 55.86049469964664, 'Prostate': 69.89616326530613, 'Salivary Gland': 48.828580246913575, 'Skin': 92.8235876174682, 'Small Intestine': 61.31058823529412, 'Spleen': 54.57709543568465, 'Stomach': 62.10077994428969, 'Testis': 60.04531855955679, 'Thyroid': 92.66070444104136, 'Uterus': 75.82373239436619, 'Vagina': 72.00852564102564}
|
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92.65, 91.77, 91.33, 92.42, 92.89, 92.52, 92.96, 92.62, 93.52, 93.2, 91.65, 91.74, 92.42, 91.4, 89.85, 92.58, 93.0, 91.88, 92.77, 92.58, 92.21, 91.96, 91.15, 91.76, 90.21, 88.73, 88.0, 87.27, 83.14, 77.4, 61.67, 48.7, 41.35]
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[1.0, 1.0, 0.97, 1.0, 0.98, 0.74, 0.91, 0.65, 0.72, 0.56, 0.65, 0.63, 0.51, 0.55, 0.69, 0.63, 0.58, 0.71, 0.75, 0.46, 0.72, 0.53, 0.53, 0.36, 0.66, 0.78, 0.22, 0.08, 0.0, 0.33, 0.16, 0.0, 0.15, 0.41, 0.0, 0.13, 0.7, 0.36, 0.0, 0.17, 0.26, 0.02, 0.01, 0.69, 0.42, 0.02, 0.15, 0.53, 0.04, 0.0, 0.41, 0.42, 0.0, 0.04, 0.45, 0.11, 0.0, 0.26, 0.58, 0.07, 0.5, 0.69, 0.29, 0.85, 0.48, 0.1, 0.65, 0.87, 0.09, 0.05, 0.51, 0.54, 0.71, 0.18, 0.09, 0.6, 0.42, 0.0, 0.39, 0.35, 0.18, 0.1, 0.65, 0.52, 0.01, 0.59, 0.45, 0.15, 0.24, 0.55, 0.41, 0.0, 0.52, 0.7, 0.32, 0.23, 0.0, 0.06, 0.0, 0.0, 0.0, 0.01, 0.0, 0.35, 0.35, 0.64, 0.05, 0.21, 0.07, 0.1, 0.16, 0.0, 0.0, 0.0, 0.0, 0.02, 0.02, 0.43, 0.38, 0.51, 0.01, 0.01, 0.12, 0.39, 0.52, 0.96, 0.88, 0.52, 0.71, 0.23, 0.39, 0.01, 0.0, 0.02, 0.16, 0.0, 0.25, 0.27, 0.15, 0.83, 0.43, 0.84, 0.64, 0.11, 0.24, 0.07, 0.27, 0.23, 0.64, 1.0, 0.43, 0.89, 0.52, 0.71, 0.38, 0.52, 0.04, 0.72, 0.5, 0.21, 0.76, 0.46, 0.04, 0.2, 0.58, 0.26, 0.14, 0.83, 0.64, 0.15, 0.88, 0.81, 0.12, 0.58, 0.21, 0.24, 0.13, 0.12, 0.03, 0.09, 0.01, 0.1, 0.07, 0.01, 0.18, 0.88, 0.53, 0.03, 0.66, 0.1, 0.04, 0.64, 0.05, 0.27, 0.0, 0.02, 0.0, 0.01, 0.0, 0.01, 0.01, 0.04, 0.05, 0.56, 0.67, 0.25, 0.85, 0.68, 0.06, 0.37, 0.41, 0.05, 0.03, 0.51, 0.73, 0.05, 0.01, 0.46, 0.46, 0.14, 0.07, 0.0, 0.0, 0.0, 0.01, 0.0, 0.03, 0.18, 0.08, 0.57, 0.33, 0.46, 0.1, 0.29, 0.71, 0.49, 0.02, 0.11, 0.51, 0.0, 0.0, 0.33, 0.18, 0.01, 0.28, 0.8, 0.62, 0.21, 0.99, 0.66, 0.08, 0.22, 0.02, 0.0, 0.0, 0.0, 0.03, 0.05, 0.39, 0.07, 0.21, 0.35, 0.17, 0.28, 0.75, 0.58, 0.64, 0.88, 0.64, 0.39, 0.72, 0.45, 0.32, 0.32, 0.64, 0.46, 0.07, 0.37, 0.54, 0.34, 0.01, 0.1, 0.27, 0.0, 0.0, 0.24, 0.61, 0.43, 0.11, 0.53, 0.08, 0.17, 0.56, 0.55, 0.85, 0.42, 0.01, 0.46, 0.38, 0.19, 0.02, 0.05, 0.03, 0.0, 0.02, 0.01, 0.55, 0.01, 0.02, 0.04, 0.31, 0.01, 0.04, 0.19, 0.29, 0.51, 0.69, 0.61, 0.82, 0.56, 0.79, 0.37, 0.56, 0.67, 0.01, 0.42, 0.46, 0.3, 0.87, 0.41, 0.12, 0.69, 0.64, 0.06, 0.09, 0.58, 0.2, 0.0, 0.48, 0.33, 0.0, 0.14, 0.39, 0.43, 0.0, 0.16, 0.32, 0.12, 0.0, 0.02, 0.6, 0.24, 0.0, 0.0, 0.5, 0.66, 0.08, 0.0, 0.42, 0.77, 0.16, 0.02, 0.51, 0.4, 0.01, 0.27, 0.5, 0.01, 0.03, 0.41, 0.23, 0.0, 0.33, 0.59, 0.11, 0.0, 0.26, 0.47, 0.0, 0.19, 0.58, 0.3, 0.0, 0.55, 0.74, 0.1, 0.17, 0.44, 0.56, 0.07, 0.31, 0.6, 0.27, 0.28, 0.59, 0.6, 0.35, 0.41, 0.54, 0.36, 0.14, 0.52, 0.45, 0.01, 0.4, 0.68, 0.32, 0.18, 0.69, 0.51, 0.16, 0.33, 0.64, 0.39, 0.04, 0.74, 0.58, 0.35, 0.1, 0.58, 0.63, 0.15, 0.09, 0.53, 0.38, 0.04, 0.39, 0.6, 0.34, 0.0, 0.24, 0.42, 0.1, 0.0, 0.3, 0.31, 0.09, 0.05, 0.71, 0.53, 0.02, 0.43, 0.57, 0.18, 0.0, 0.64, 0.6, 0.08, 0.9, 0.35, 0.82, 0.11, 0.62, 0.45, 0.4, 0.7, 0.76, 0.36, 0.11, 0.68, 0.57, 0.01, 0.15, 0.58, 0.33, 0.0, 0.06, 0.51, 0.34, 0.03, 0.35, 0.41, 0.12, 0.02, 0.27, 0.6, 0.34, 0.0, 0.37, 0.73, 0.39, 0.04, 0.17, 0.58, 0.4, 0.02, 0.25, 0.49, 0.36, 0.04, 0.58, 0.55, 0.04, 0.23, 0.48, 0.36, 0.0, 0.13, 0.47, 0.27, 0.02, 0.42, 0.5, 0.02, 0.06, 0.39, 0.71, 0.66, 0.28, 0.36, 0.77, 0.54, 0.05, 0.63, 0.88, 0.39, 0.17, 0.66, 0.84, 0.82, 0.9, 0.18, 0.73, 0.1, 0.59, 0.08, 0.48, 0.07, 0.34, 0.02, 0.5, 0.78, 0.24, 0.03, 0.64, 0.51, 0.07, 0.91, 0.33, 0.4, 0.15, 0.72, 0.22, 0.45, 0.08, 0.57, 0.43, 0.16, 0.77, 0.58, 0.39, 0.38, 0.27, 0.36, 0.9, 0.83, 0.54, 0.34, 0.68, 0.87, 0.51, 0.05, 0.77, 0.72, 0.69, 0.69, 0.77, 0.92, 0.97, 0.97, 0.79, 0.96, 0.85, 0.99, 0.96, 1.0, 0.97, 1.0, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 1.0, 0.98, 0.99, 0.98, 0.99, 0.97, 0.97, 0.97, 0.65, 0.84, 0.77, 0.72, 0.71, 0.74, 0.64, 0.59, 0.65, 0.71, 0.62, 0.55, 0.82, 0.68, 0.74, 0.87, 0.93, 0.61, 0.92, 0.72, 0.45, 0.68, 0.46, 0.73, 0.69, 0.59, 0.62, 0.45, 0.44, 0.6, 0.44, 0.63, 0.88, 0.81, 0.46, 0.4, 0.72, 0.85, 0.58, 0.22, 0.51, 0.64, 0.55, 0.7, 0.45, 0.59, 0.38, 0.34, 0.68, 0.37, 0.38, 0.53, 0.65, 0.23, 0.53, 0.72, 0.43, 0.34, 0.5, 0.5, 0.66, 0.19, 0.24, 0.24, 0.65, 0.18, 0.0, 0.09, 0.67, 0.27, 0.01, 0.2, 0.72, 0.19, 0.01, 0.16, 0.67, 0.27, 0.01, 0.58, 0.71, 0.15, 0.16, 0.6, 0.6, 0.01, 0.0, 0.47, 0.29, 0.0, 0.09, 0.5, 0.17, 0.0, 0.45, 0.6, 0.47, 0.0, 0.38, 0.47, 0.11, 0.16, 0.54, 0.33, 0.05, 0.17, 0.59, 0.28, 0.0, 0.31, 0.47, 0.12, 0.32, 0.53, 0.47, 0.1, 0.42, 0.62, 0.41, 0.14, 0.52, 0.47, 0.26, 0.34, 0.51, 0.33, 0.11, 0.69, 0.26, 0.0, 0.55, 0.43, 0.12, 0.1, 0.57, 0.53, 0.01, 0.51, 0.53, 0.02, 0.34, 0.58, 0.32, 0.04, 0.46, 0.52, 0.03, 0.38, 0.45, 0.13, 0.01, 0.32, 0.49, 0.01, 0.19, 0.63, 0.65, 0.11, 0.15, 0.63, 0.49, 0.92, 0.95]
| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 81.506447
| 0.384795
| 784
|
O60260
|
O95147
|
26387737
|
UbiBrowser
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
|
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
|
{}
|
DUSP14
|
MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKESRHLMPYWGI
|
Homo sapiens
| null |
Tissue enhanced (skin)
|
{'Ciliated cells': '87.0', 'Basal respiratory cells': '70.6', 'Club cells': '27.3', 'Ionocytes': '47.5', 'Mucus glandular cells': '15.4', 'Serous glandular cells': '9.7', 'Gastric mucus-secreting cells': '3.5', 'Proximal enterocytes': '0.2', 'Paneth cells': '2.5', 'Distal enterocytes': '0.3', 'Intestinal goblet cells': '1.7', 'Exocrine glandular cells': '-0.437', 'Basal prostatic cells': '18.5', 'Prostatic glandular cells': '8.1', 'Breast glandular cells': '0.239', 'Breast myoepithelial cells': '0.445', 'Glandular and luminal cells': '92.5', 'Secretory cells': '50.8', 'Basal keratinocytes': '116.8', 'Suprabasal keratinocytes': '61.2', 'Basal squamous epithelial cells': '94.8', 'Squamous epithelial cells': '34.7', 'Alveolar cells type 1': '0.073', 'Alveolar cells type 2': '-0.108', 'Salivary duct cells': '16.6', 'Ductal cells': '0.520', 'Hepatocytes': '0.451', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.298', 'Distal tubular cells': '36.9', 'Collecting duct cells': '7.8', 'Mesothelial cells': '-0.070', 'Sertoli cells': '0.029', 'Granulosa cells': '18.5', 'Enteroendocrine cells': '1.8', 'Pancreatic endocrine cells': '52.6', 'Leydig cells': '-0.155', 'Excitatory neurons': '11.6', 'Inhibitory neurons': '5.1', 'Cone photoreceptor cells': '18.7', 'Rod photoreceptor cells': '22.5', 'Bipolar cells': '7.8', 'Horizontal cells': '7.6', 'Astrocytes': '2.8', 'Oligodendrocyte precursor cells': '2.8', 'Oligodendrocytes': '3.1', 'Microglial cells': '4.5', 'Muller glia cells': '18.5', 'Schwann cells': '0.082', 'Spermatogonia': '0.215', 'Spermatocytes': '0.353', 'Early spermatids': '0.406', 'Late spermatids': '0.204', 'Oocytes': '36.0', 'Cytotrophoblasts': '167.4', 'Syncytiotrophoblasts': '68.9', 'Extravillous trophoblasts': '82.7', 'Endothelial cells': '16.5', 'Lymphatic endothelial cells': '7.1', 'Cardiomyocytes': '0.642', 'Skeletal myocytes': '-0.026', 'Smooth muscle cells': '25.4', 'Adipocytes': '14.5', 'Melanocytes': '0.360', 'Fibroblasts': '31.9', 'Peritubular cells': '-0.105', 'Endometrial stromal cells': '18.9', 'Ovarian stromal cells': '10.4', 'Undifferentiated cells': '4.4', 'T-cells': '15.8', 'B-cells': '8.7', 'Plasma cells': '8.5', 'Nk-cells': '17.2', 'Granulocytes': '74.8', 'Monocytes': '1.7', 'Macrophages': '7.0', 'Hofbauer cells': '10.8', 'Kupffer cells': '3.9', 'Dendritic cells': '11.3', 'Langerhans cells': '0.029', 'Erythroid cells': '-0.094', 'Adipocytes (Subcutaneous)': '0.013', 'Adipocytes (Visceral)': '0.321', 'Breast glandular cells (progenitors)': '0.307', 'Adipocytes (Breast)': '-0.354', 'Colon enterocytes': '-0.174', 'Colon enteroendocrine cells': '0.238', 'Enteric glia cells': '0.153', 'Mitotic cells (Colon)': '-0.157', 'Mitotic cells (Heart)': '0.528', 'Podocytes': '0.026', 'Ascending Loop of Henle cells': '0.296', 'Intercalated cells': '0.042', 'Cholangiocyte': '0.264', 'NK-cells (Liver)': '-0.122', 'Respiratory ciliated cells': '0.209', 'Mitotic cells (Lung)': '0.028', 'NK-cells (Lung)': '0.150', 'B-cells (Lung)': '0.046', 'Alpha cells': '0.289', 'Beta cells': '0.152', 'Prostate glandular cells': '0.165', 'Prostate basal glandular cells': '0.221', 'Urothelial cells': '0.134', 'Keratinocyte (other)': '-0.007', 'Keratinocyte (granular)': '0.311', 'Hair cortex cells': '0.506', 'Inner root sheath cells': '0.442', 'Outer root sheath cells': '0.201', 'Sebaceous gland cells': '-0.061', 'Eccrine sweat gland cells': '0.053', 'Adipocytes (Skin)': '0.088', 'Mitotic cells (Skin)': '0.267', 'Parietal cells': '-0.643', 'Chief cells': '-0.543', 'Gastric mucous cells': '-0.547', 'Gastric enteroendocrine cells': '-0.446', 'Mitotic cells (Stomach)': '-0.113', 'Parafollicular cells': '0.154', 'Thyroid glandular cells': '0.551', 'Mitotic cells (Thyroid)': '-0.052', 'Adrenal cortex cells': '0.547', 'Adrenal medulla cells': '0.103', 'Mitotic cells (Adrenal gland)': '0.384', 'Minor salivary glandular cells': '0.172', 'Minor salivary gland ductal cells': '-0.263', 'Minor salivary gland basal cells': '0.674', 'Mitotic cells (Minor salivary gland)': '0.569', 'Adipocytes (Minor salivary gland)': '0.163', 'Somatotropes': '-0.363', 'Lactotropes': '0.061', 'Gonadotropes': '0.294', 'Corticotropes': '0.211', 'Thyrotropes': '0.428', 'Undifferentiated cells (Pituitary gland)': '0.187', 'Mitotic cells (Spleen)': '-0.120', 'Platelets': '-0.108', 'Erythrocytes': '-0.169', 'Hematopoietic stem cells': '-0.140', 'B-cells (Spleen)': '0.164', 'NK-cells (Spleen)': '0.117', 'Amygdala excitatory': '13.7', 'Cerebellar inhibitory': '6.5', 'Cge interneuron': '6.0', 'Deep-layer corticothalamic and 6b': '13.6', 'Deep-layer intratelencephalic': '14.6', 'Deep-layer near-projecting': '9.3', 'Eccentric medium spiny neuron': '15.7', 'Hippocampal ca1-3': '8.5', 'Hippocampal ca4': '8.5', 'Hippocampal dentate gyrus': '31.4', 'Lamp5-lhx6 and chandelier': '5.7', 'Lower rhombic lip': '6.9', 'Mammillary body': '6.6', 'Medium spiny neuron': '23.4', 'Mge interneuron': '6.5', 'Midbrain-derived inhibitory': '5.1', 'Miscellaneous': '11.4', 'Splatter': '7.0', 'Thalamic excitatory': '19.7', 'Upper rhombic lip': '9.6', 'Upper-layer intratelencephalic': '25.2', 'Astrocyte': '8.0', 'Bergmann glia': '6.3', 'Central nervous system macrophage': '2.7', 'Choroid plexus epithelial cell': '12.1', 'Committed oligodendrocyte precursor': '5.8', 'Ependymal cell': '36.8', 'Oligodendrocyte': '2.8', 'Oligodendrocyte precursor cell': '3.9', 'Endothelial cell': '5.2', 'Pericyte': '7.8', 'Vascular associated smooth muscle cell': '7.4', 'Fibroblast': '8.0', 'Leukocyte': '4.9', 'Basophil': '1.6', 'Eosinophil': '0.7', 'Neutrophil': '4.0', 'Classical monocyte': '0.8', 'Non-classical monocyte': '0.3', 'Intermediate monocyte': '2.8', 'T-reg': '10.5', 'GdT-cell': '0.1', 'MAIT T-cell': '10.8', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '6.3', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '8.3', 'Memory B-cell': '0.2', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '11.3', 'Myeloid DC': '4.5', 'NK-cell': '12.2', 'Total PBMC': '8.6', 'Vd2 gdTCR': '15.3', 'Memory CD4 T-cell Th1\\/Th17': '7.6', 'Memory CD4 T-cell Th17': '8.3', 'Memory CD4 T-cell Th2': '7.8', 'Non-Vd2 gdTCR': '13.8', 'Memory CD4 T-cell Th1': '8.7', 'Memory CD4 T-cell TFH': '7.8', 'Terminal effector memory CD4 T-cell': '22.6', 'Central memory CD8 T-cell': '14.5', 'Effector memory CD8 T-cell': '16.5', 'Terminal effector memory CD8 T-cell': '15.1', 'Non-switched memory B-cell': '9.1', 'Plasmablast': '9.2', 'Switched memory B-cell': '12.0', 'Exhausted memory B-cell': '6.5', 'Progenitor cell': '14.7', 'Memory T-reg': '4.0', 'Naive CD4 T-cell activated': '25.7', 'Naive CD8 T-cell activated': '35.1', 'Naive T-reg': '4.7'}
|
2WGP
|
{'Adipose Tissue': 16.043288205980065, 'Adrenal Gland': 13.569666666666668, 'Bladder': 9.470857142857144, 'Blood': 2.5350394187298173, 'Blood Vessel': 9.15414456928839, 'Brain': 12.52115704012112, 'Breast': 15.715858387799564, 'Cervix Uteri': 13.139684210526315, 'Colon': 9.645311296534018, 'Esophagus': 15.335196539792388, 'Fallopian Tube': 11.873555555555557, 'Heart': 6.976146457607433, 'Kidney': 6.434606741573033, 'Liver': 7.375380530973452, 'Lung': 12.26168858131488, 'Muscle': 5.847551681195516, 'Nerve': 16.203222940226173, 'Ovary': 8.411005555555555, 'Pancreas': 3.070918292682927, 'Pituitary': 19.86635335689046, 'Prostate': 8.865910204081633, 'Salivary Gland': 13.679648148148148, 'Skin': 48.881050304035384, 'Small Intestine': 6.730732085561497, 'Spleen': 3.51859336099585, 'Stomach': 7.757225626740947, 'Testis': 22.39387811634349, 'Thyroid': 36.78241807044411, 'Uterus': 12.82826056338028, 'Vagina': 21.23171153846154}
|
[86.6, 87.14, 88.61, 89.01, 89.67, 88.44, 87.46, 83.77, 82.45, 81.33, 82.97, 84.74, 86.57, 89.57, 90.1, 90.69, 89.67, 90.34, 87.71, 89.23, 89.95, 93.02, 92.3, 92.09, 92.37, 91.58, 92.58, 92.83, 92.29, 90.48, 91.02, 91.12, 88.85, 86.99, 87.58, 87.73, 90.05, 90.01, 88.64, 86.82, 89.42, 87.19, 90.11, 87.28, 86.12, 78.81, 73.0, 79.54, 85.09, 87.69, 88.54, 89.59, 88.97, 88.84, 90.12, 86.33, 83.17, 85.28, 79.1, 80.69, 81.01, 82.27, 82.43, 81.52, 86.22, 87.46, 90.66, 87.7, 89.96, 86.4, 86.05, 77.55, 70.82, 62.18, 61.34, 52.16, 38.83, 44.34, 30.73, 31.43, 26.08, 27.82, 32.43, 27.17, 32.44, 31.46, 28.93, 37.69, 33.58, 33.3, 32.79, 32.77, 31.16, 30.63, 29.11, 31.16, 33.22, 35.12, 33.91, 30.34, 35.05, 29.65, 35.87, 27.96, 32.25, 26.15, 30.35, 26.66, 31.89, 33.33, 30.55, 30.74, 35.12, 32.39, 29.71, 33.62, 34.73, 26.72, 31.71, 28.39, 33.89, 31.11, 34.89, 29.86, 26.98, 29.31, 28.71, 29.87, 26.72, 29.64, 28.01, 35.03, 32.42, 26.03, 26.21, 25.78, 27.97, 25.32, 28.69, 42.33, 50.14, 59.81, 73.34, 80.84, 81.26, 91.68, 94.51, 94.99, 94.31, 93.33, 90.47, 88.44, 92.04, 91.72, 91.25, 91.84, 94.01, 93.92, 93.04, 90.7, 89.16, 91.17, 90.11, 90.68, 90.26, 89.74, 92.18, 92.02, 90.56, 89.44, 86.56, 84.44, 85.5, 85.08, 87.47, 89.13, 87.45, 87.73, 87.57, 91.74, 90.15, 90.56, 90.97, 92.39, 92.62, 91.9, 92.26, 92.16, 91.66, 90.75, 92.44, 91.33, 92.54, 90.83, 90.48, 89.4, 89.6, 84.64, 87.28, 87.95, 84.16, 91.86, 89.62, 92.55, 93.61, 92.4, 93.23, 93.33, 92.76, 93.56, 91.0, 92.54, 89.74, 89.48, 89.91, 88.33, 86.79, 86.93, 80.65, 84.69, 87.55, 91.61, 92.58, 92.61, 93.6, 93.85, 92.89, 94.12, 94.58, 91.59, 90.69, 90.31, 84.69, 83.48, 87.8, 89.95, 93.44, 94.32, 93.73, 90.77, 90.73, 91.35, 92.61, 92.07, 91.36, 91.1, 93.93, 94.82, 95.89, 95.03, 95.16, 92.39, 92.77, 90.89, 89.77, 91.95, 94.22, 94.76, 95.62, 95.26, 94.61, 92.28, 93.2, 95.01, 93.32, 91.52, 93.54, 93.31, 91.4, 89.65, 91.18, 89.05, 88.05, 87.94, 88.85, 89.82, 91.79, 92.63, 92.54, 92.06, 89.88, 89.67, 89.07, 91.55, 93.84, 94.98, 95.12, 95.1, 94.48, 92.52, 90.87, 90.19, 92.01, 91.36, 90.6, 93.83, 94.81, 95.01, 93.21, 91.96, 93.44, 92.68, 94.49, 95.0, 93.51, 92.8, 91.23, 90.04, 89.36, 88.14, 90.5, 92.38, 90.6, 90.2, 92.1, 91.02, 89.08, 89.88, 86.7, 86.54, 88.71, 88.57, 86.26, 88.98, 88.9, 88.32, 88.97, 87.29, 88.96, 89.96, 89.35, 88.03, 85.91, 82.77, 75.14, 75.43, 80.18, 79.23, 84.69, 85.78, 87.42, 87.75, 87.16, 87.6, 84.92, 85.06, 88.44, 89.95, 91.76, 90.7, 90.29, 87.05, 79.67, 62.52, 56.91, 60.2, 56.44, 65.23, 71.08, 83.76, 85.05, 87.42, 91.12, 91.7, 91.75, 88.29, 87.13, 85.75, 85.93, 86.7, 89.58, 90.19, 90.4, 86.67, 89.15, 87.4, 86.34, 78.61, 70.66, 66.43, 65.14, 58.91, 50.78, 46.67, 36.54, 35.27, 32.59, 40.61, 47.31, 50.77, 62.41, 70.48, 78.66, 85.25, 86.67, 88.92, 89.3, 88.85, 87.79, 87.66, 89.94, 91.09, 85.42, 72.16, 57.86, 51.98, 52.44, 47.51, 45.51, 48.58, 51.24, 52.02, 56.52, 70.54, 78.5, 85.42, 88.76, 89.24, 92.22, 89.92, 91.66, 88.73, 88.39, 87.92, 87.02, 85.8, 83.44, 74.02, 80.21, 84.48, 87.59, 88.21, 89.27, 90.78, 91.24, 91.53, 90.4, 90.16, 90.37, 90.19, 90.87, 89.71, 92.15, 92.34, 93.0, 92.02, 89.02, 86.0, 88.39, 88.77, 90.21, 92.62, 91.03, 89.53, 85.52, 87.96, 88.06, 86.94, 83.84, 86.53, 86.56, 87.5, 88.23, 82.06, 76.01]
|
[0.3, 0.19, 0.02, 0.02, 0.0, 0.08, 0.07, 0.12, 0.1, 0.29, 0.13, 0.0, 0.08, 0.4, 0.08, 0.86, 0.06, 0.64, 0.51, 0.76, 0.17, 0.23, 0.0, 0.42, 0.46, 0.04, 0.05, 0.38, 0.51, 0.01, 0.11, 0.81, 0.61, 0.34, 0.79, 0.2, 0.5, 0.2, 0.8, 0.29, 0.02, 0.07, 0.0, 0.01, 0.15, 0.37, 0.23, 0.67, 0.42, 0.05, 0.57, 0.41, 0.67, 0.4, 0.24, 0.03, 0.72, 0.65, 0.11, 0.71, 0.08, 0.66, 0.59, 0.49, 0.11, 0.22, 0.01, 0.08, 0.0, 0.01, 0.37, 0.2, 0.55, 0.58, 0.7, 0.7, 0.84, 0.57, 0.73, 0.81, 0.94, 0.84, 0.96, 0.99, 0.81, 0.96, 0.91, 0.93, 0.96, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.85, 1.0, 0.81, 1.0, 0.98, 1.0, 1.0, 0.92, 0.96, 0.94, 0.94, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 0.99, 1.0, 0.97, 0.92, 0.92, 0.75, 0.78, 0.77, 0.81, 0.93, 0.83, 0.96, 0.85, 0.98, 0.87, 0.9, 0.95, 0.92, 0.95, 0.89, 0.92, 0.71, 0.94, 0.91, 0.74, 0.82, 0.75, 0.29, 0.14, 0.04, 0.0, 0.11, 0.0, 0.06, 0.01, 0.58, 0.68, 0.79, 0.26, 0.47, 0.55, 0.25, 0.12, 0.33, 0.01, 0.29, 0.0, 0.29, 0.17, 0.19, 0.0, 0.34, 0.62, 0.34, 0.7, 0.44, 0.77, 0.3, 0.1, 0.56, 0.2, 0.72, 0.7, 0.29, 0.0, 0.35, 0.39, 0.12, 0.55, 0.1, 0.09, 0.46, 0.53, 0.91, 0.61, 0.66, 0.06, 0.52, 0.15, 0.67, 0.09, 0.58, 0.2, 0.92, 0.94, 0.2, 0.75, 0.03, 0.58, 0.27, 0.07, 0.36, 0.13, 0.14, 0.05, 0.08, 0.01, 0.27, 0.61, 0.25, 0.98, 0.26, 0.48, 0.67, 0.89, 0.48, 0.65, 0.17, 0.33, 0.13, 0.0, 0.25, 0.06, 0.0, 0.07, 0.24, 0.07, 0.57, 0.29, 0.62, 0.08, 0.21, 0.03, 0.02, 0.38, 0.34, 0.49, 0.4, 0.52, 0.22, 0.35, 0.18, 0.03, 0.0, 0.11, 0.01, 0.36, 0.01, 0.91, 0.29, 0.35, 0.05, 0.0, 0.0, 0.04, 0.15, 0.22, 0.12, 0.0, 0.06, 0.1, 0.06, 0.0, 0.0, 0.06, 0.12, 0.05, 0.0, 0.23, 0.21, 0.37, 0.08, 0.41, 0.59, 0.35, 0.85, 0.96, 0.29, 0.3, 0.17, 0.0, 0.01, 0.25, 0.01, 0.06, 0.39, 0.69, 0.21, 0.89, 0.89, 0.02, 0.23, 0.02, 0.66, 0.33, 0.25, 0.35, 0.0, 0.0, 0.22, 0.15, 0.08, 0.26, 0.49, 0.63, 0.07, 0.1, 0.55, 0.22, 0.1, 0.6, 0.58, 0.02, 0.34, 0.5, 0.15, 0.19, 0.41, 0.17, 0.36, 0.74, 0.62, 0.43, 0.18, 0.07, 0.12, 0.04, 0.09, 0.48, 0.45, 0.84, 0.29, 0.3, 0.3, 0.5, 0.1, 0.62, 0.25, 0.79, 0.77, 0.95, 0.45, 0.33, 0.46, 0.03, 0.36, 0.02, 0.78, 0.39, 0.94, 0.86, 0.76, 0.8, 0.31, 0.26, 0.61, 0.25, 0.31, 0.0, 0.0, 0.26, 0.69, 0.1, 0.33, 0.4, 0.53, 0.34, 0.3, 0.81, 0.61, 0.91, 0.29, 0.58, 0.75, 0.28, 0.48, 0.19, 0.6, 0.79, 0.73, 0.43, 0.82, 0.53, 0.59, 0.64, 0.21, 0.83, 0.24, 0.61, 0.77, 0.74, 0.06, 0.14, 0.6, 0.56, 0.0, 0.4, 0.08, 0.56, 0.62, 0.3, 0.5, 0.86, 0.92, 0.48, 0.7, 0.74, 0.73, 0.51, 0.52, 0.31, 0.61, 0.0, 0.37, 0.59, 0.36, 0.65, 0.32, 0.69, 0.07, 0.6, 0.25, 0.76, 0.64, 0.19, 0.13, 0.03, 0.35, 0.08, 0.61, 0.05, 0.67, 0.47, 0.64, 0.99, 0.12, 0.63, 0.08, 0.36, 0.02, 0.0, 0.08, 0.5, 0.34, 0.38, 0.36, 0.68, 0.18, 0.4, 0.75, 0.63, 0.04, 0.25, 0.01, 0.14, 0.06, 0.05, 0.01, 0.45, 0.31]
|
[40.56, 41.69, 40.7, 47.09, 40.02, 41.3, 44.09, 39.35, 42.95, 34.78, 36.49, 40.95, 44.42, 36.86, 37.02, 32.86, 38.26, 36.12, 40.25, 44.16, 42.92, 46.11, 49.39, 57.0, 71.96, 91.66, 96.95, 97.78, 97.98, 98.49, 98.19, 96.92, 97.66, 98.82, 98.7, 98.68, 97.47, 97.11, 96.53, 95.62, 95.96, 95.74, 94.65, 95.53, 96.19, 95.73, 95.75, 97.27, 96.88, 96.07, 95.91, 96.99, 98.5, 98.58, 98.79, 98.84, 98.88, 98.79, 98.73, 98.48, 98.05, 97.5, 97.36, 96.69, 97.69, 95.69, 95.48, 97.28, 96.41, 95.56, 98.2, 98.26, 98.56, 98.54, 98.54, 98.63, 98.01, 97.03, 97.78, 98.23, 98.45, 97.94, 97.96, 98.5, 98.42, 98.84, 98.73, 98.59, 98.84, 98.86, 98.79, 98.7, 98.89, 98.88, 98.8, 98.85, 98.85, 98.71, 98.71, 98.73, 98.44, 98.34, 97.99, 97.37, 98.28, 98.69, 98.89, 98.77, 98.91, 98.61, 98.14, 97.31, 96.95, 97.47, 98.02, 98.62, 98.79, 98.78, 98.81, 98.94, 98.95, 98.94, 98.95, 98.94, 98.9, 98.91, 98.85, 98.74, 98.62, 98.34, 97.6, 98.67, 98.72, 98.85, 98.69, 98.7, 98.85, 98.78, 98.44, 98.61, 98.57, 97.7, 96.96, 97.34, 97.04, 95.77, 95.95, 97.93, 97.95, 98.69, 98.4, 98.14, 98.64, 98.8, 98.81, 98.76, 98.87, 98.93, 98.86, 98.81, 98.86, 98.83, 98.73, 98.58, 98.61, 98.51, 98.23, 97.45, 97.9, 98.52, 98.6, 98.03, 98.36, 97.47, 96.78, 93.21, 92.72, 89.05, 93.51, 96.78, 97.27, 97.9, 97.57, 97.18, 95.76, 92.32, 90.94, 87.12, 80.38, 76.14, 68.8, 69.01, 57.76, 49.68, 44.99, 43.1, 44.69, 45.61]
|
[0.98, 0.92, 0.89, 0.91, 0.85, 0.85, 0.62, 0.84, 0.47, 0.63, 0.86, 0.87, 0.65, 0.84, 0.78, 0.88, 0.9, 0.92, 0.92, 0.67, 0.67, 0.12, 0.8, 0.93, 0.47, 0.12, 0.04, 0.01, 0.51, 0.02, 0.17, 0.79, 0.09, 0.0, 0.03, 0.0, 0.0, 0.47, 0.1, 0.62, 0.03, 0.01, 0.47, 0.42, 0.39, 0.75, 0.24, 0.0, 0.48, 0.78, 0.35, 0.44, 0.04, 0.37, 0.01, 0.01, 0.0, 0.0, 0.01, 0.0, 0.59, 0.63, 0.22, 0.75, 0.26, 0.37, 0.68, 0.22, 0.91, 0.46, 0.07, 0.47, 0.23, 0.25, 0.37, 0.01, 0.48, 0.09, 0.36, 0.37, 0.51, 0.46, 0.81, 0.07, 0.42, 0.0, 0.31, 0.76, 0.29, 0.01, 0.41, 0.61, 0.01, 0.0, 0.41, 0.28, 0.0, 0.35, 0.4, 0.07, 0.31, 0.75, 0.73, 0.89, 0.11, 0.04, 0.0, 0.0, 0.0, 0.02, 0.01, 0.42, 0.36, 0.0, 0.26, 0.06, 0.04, 0.0, 0.0, 0.0, 0.01, 0.0, 0.0, 0.01, 0.04, 0.02, 0.0, 0.37, 0.38, 0.34, 0.56, 0.11, 0.23, 0.0, 0.33, 0.53, 0.01, 0.02, 0.52, 0.23, 0.0, 0.25, 0.73, 0.28, 0.05, 0.59, 0.47, 0.01, 0.54, 0.03, 0.16, 0.32, 0.1, 0.0, 0.0, 0.49, 0.22, 0.0, 0.05, 0.44, 0.04, 0.01, 0.52, 0.76, 0.42, 0.33, 0.76, 0.67, 0.3, 0.34, 0.02, 0.71, 0.29, 0.25, 0.76, 0.19, 0.99, 0.89, 0.3, 0.43, 0.23, 0.0, 0.13, 0.09, 0.06, 0.22, 0.51, 0.31, 0.45, 0.63, 0.82, 0.78, 0.69, 0.65, 0.96, 0.74, 0.87, 0.87]
| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 88.720657
| 0.360657
| 2,743
|
O60260
|
O95602
|
33082525
|
DegPred
|
PRKN
|
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
|
Homo sapiens
|
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
|
Tissue enhanced (skeletal muscle, tongue)
|
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
|
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
|
{}
|
POLR1A
|
MLISKNMPWRRLQGISFGMYSAEELKKLSVKSITNPRYLDSLGNPSANGLYDLALGPADSKEVCSTCVQDFSNCSGHLGHIELPLTVYNPLLFDKLYLLLRGSCLNCHMLTCPRAVIHLLLCQLRVLEVGALQAVYELERILNRFLEENPDPSASEIREELEQYTTEIVQNNLLGSQGAHVKNVCESKSKLIALFWKAHMNAKRCPHCKTGRSVVRKEHNSKLTITFPAMVHRTAGQKDSEPLGIEEAQIGKRGYLTPTSAREHLSALWKNEGFFLNYLFSGMDDDGMESRFNPSVFFLDFLVVPPSRYRPVSRLGDQMFTNGQTVNLQAVMKDVVLIRKLLALMAQEQKLPEEVATPTTDEEKDSLIAIDRSFLSTLPGQSLIDKLYNIWIRLQSHVNIVFDSEMDKLMMDKYPGIRQILEKKEGLFRKHMMGKRVDYAARSVICPDMYINTNEIGIPMVFATKLTYPQPVTPWNVQELRQAVINGPNVHPGASMVINEDGSRTALSAVDMTQREAVAKQLLTPATGAPKPQGTKIVCRHVKNGDILLLNRQPTLHRPSIQAHRARILPEEKVLRLHYANCKAYNADFDGDEMNAHFPQSELGRAEAYVLACTDQQYLVPKDGQPLAGLIQDHMVSGASMTTRGCFFTREHYMELVYRGLTDKVGRVKLLSPSILKPFPLWTGKQVVSTLLINIIPEDHIPLNLSGKAKITGKAWVKETPRSVPGFNPDSMCESQVIIREGELLCGVLDKAHYGSSAYGLVHCCYEIYGGETSGKVLTCLARLFTAYLQLYRGFTLGVEDILVKPKADVKRQRIIEESTHCGPQAVRAALNLPEAASYDEVRGKWQDAHLGKDQRDFNMIDLKFKEEVNHYSNEINKACMPFGLHRQFPENSLQMMVQSGAKGSTVNTMQISCLLGQIELEGRRPPLMASGKSLPCFEPYEFTPRAGGFVTGRFLTGIKPPEFFFHCMAGREGLVDTAVKTSRSGYLQRCIIKHLEGLVVQYDLTVRDSDGSVVQFLYGEDGLDIPKTQFLQPKQFPFLASNYEVIMKSQHLHEVLSRADPKKALHHFRAIKKWQSKHPNTLLRRGAFLSYSQKIQEAVKALKLESENRNGRSPGTQEMLRMWYELDEESRRKYQKKAAACPDPSLSVWRPDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSELSLDRLRTLLQLKWQRSLCEPGEAVGLLAAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMVASANIKTPMMSVPVLNTKKALKRVKSLKKQLTRVCLGEVLQKIDVQESFCMEEKQNKFQVYQLRFQFLPHAYYQQEKCLRPEDILRFMETRFFKLLMESIKKKNNKASAFRNVNTRRATQRDLDNAGELGRSRGEQEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVREIHPFIDDYQYDTEESLWCQVTVKLPLMKINFDMSSLVVSLAHGAVIYATKGITRCLLNETTNNKNEKELVLNTEGINLPELFKYAEVLDLRRLYSNDIHAIANTYGIEAALRVIEKEIKDVFAVYGIAVDPRHLSLVADYMCFEGVYKPLNRFGIRSNSSPLQQMTFETSFQFLKQATMLGSHDELRSPSACLVVGKVVRGGTGLFELKQPLR
|
Homo sapiens
|
Nucleus, nucleolus, Chromosome
|
Low tissue specificity
|
{'Ciliated cells': '6.0', 'Basal respiratory cells': '4.8', 'Club cells': '7.7', 'Ionocytes': '4.4', 'Mucus glandular cells': '7.3', 'Serous glandular cells': '6.0', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '3.5', 'Paneth cells': '3.4', 'Distal enterocytes': '4.8', 'Intestinal goblet cells': '5.6', 'Exocrine glandular cells': '-0.659', 'Basal prostatic cells': '8.1', 'Prostatic glandular cells': '9.5', 'Breast glandular cells': '0.225', 'Breast myoepithelial cells': '0.024', 'Glandular and luminal cells': '6.7', 'Secretory cells': '7.1', 'Basal keratinocytes': '8.2', 'Suprabasal keratinocytes': '6.1', 'Basal squamous epithelial cells': '12.6', 'Squamous epithelial cells': '12.5', 'Alveolar cells type 1': '-0.114', 'Alveolar cells type 2': '0.296', 'Salivary duct cells': '7.2', 'Ductal cells': '0.617', 'Hepatocytes': '0.296', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '0.191', 'Distal tubular cells': '0.0', 'Collecting duct cells': '9.7', 'Mesothelial cells': '0.040', 'Sertoli cells': '0.103', 'Granulosa cells': '6.9', 'Enteroendocrine cells': '8.6', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.053', 'Excitatory neurons': '19.1', 'Inhibitory neurons': '17.4', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '10.5', 'Bipolar cells': '11.5', 'Horizontal cells': '15.7', 'Astrocytes': '12.7', 'Oligodendrocyte precursor cells': '18.9', 'Oligodendrocytes': '16.9', 'Microglial cells': '6.3', 'Muller glia cells': '4.1', 'Schwann cells': '-0.036', 'Spermatogonia': '0.367', 'Spermatocytes': '0.524', 'Early spermatids': '0.193', 'Late spermatids': '-0.037', 'Oocytes': '3.7', 'Cytotrophoblasts': '6.5', 'Syncytiotrophoblasts': '3.7', 'Extravillous trophoblasts': '4.6', 'Endothelial cells': '7.5', 'Lymphatic endothelial cells': '3.2', 'Cardiomyocytes': '0.595', 'Skeletal myocytes': '-0.300', 'Smooth muscle cells': '7.1', 'Adipocytes': '5.0', 'Melanocytes': '0.074', 'Fibroblasts': '8.2', 'Peritubular cells': '-0.002', 'Endometrial stromal cells': '13.6', 'Ovarian stromal cells': '3.9', 'Undifferentiated cells': '8.2', 'T-cells': '7.7', 'B-cells': '9.5', 'Plasma cells': '9.6', 'Nk-cells': '6.4', 'Granulocytes': '7.9', 'Monocytes': '3.9', 'Macrophages': '7.7', 'Hofbauer cells': '11.5', 'Kupffer cells': '3.1', 'Dendritic cells': '8.3', 'Langerhans cells': '0.030', 'Erythroid cells': '-0.196', 'Adipocytes (Subcutaneous)': '0.096', 'Adipocytes (Visceral)': '0.155', 'Breast glandular cells (progenitors)': '0.106', 'Adipocytes (Breast)': '0.014', 'Colon enterocytes': '-0.051', 'Colon enteroendocrine cells': '0.086', 'Enteric glia cells': '-0.285', 'Mitotic cells (Colon)': '-0.022', 'Mitotic cells (Heart)': '0.469', 'Podocytes': '-0.255', 'Ascending Loop of Henle cells': '0.448', 'Intercalated cells': '-0.108', 'Cholangiocyte': '0.250', 'NK-cells (Liver)': '-0.392', 'Respiratory ciliated cells': '-0.099', 'Mitotic cells (Lung)': '0.138', 'NK-cells (Lung)': '-0.257', 'B-cells (Lung)': '-0.212', 'Alpha cells': '0.399', 'Beta cells': '0.291', 'Prostate glandular cells': '-0.031', 'Prostate basal glandular cells': '0.205', 'Urothelial cells': '0.128', 'Keratinocyte (other)': '-0.195', 'Keratinocyte (granular)': '-0.048', 'Hair cortex cells': '0.264', 'Inner root sheath cells': '0.270', 'Outer root sheath cells': '0.202', 'Sebaceous gland cells': '0.212', 'Eccrine sweat gland cells': '0.088', 'Adipocytes (Skin)': '0.181', 'Mitotic cells (Skin)': '0.157', 'Parietal cells': '-0.515', 'Chief cells': '-0.473', 'Gastric mucous cells': '-0.278', 'Gastric enteroendocrine cells': '-0.350', 'Mitotic cells (Stomach)': '0.180', 'Parafollicular cells': '0.091', 'Thyroid glandular cells': '0.375', 'Mitotic cells (Thyroid)': '-0.119', 'Adrenal cortex cells': '0.399', 'Adrenal medulla cells': '-0.026', 'Mitotic cells (Adrenal gland)': '0.113', 'Minor salivary glandular cells': '0.367', 'Minor salivary gland ductal cells': '-0.070', 'Minor salivary gland basal cells': '0.551', 'Mitotic cells (Minor salivary gland)': '0.587', 'Adipocytes (Minor salivary gland)': '0.241', 'Somatotropes': '0.018', 'Lactotropes': '-0.163', 'Gonadotropes': '-0.021', 'Corticotropes': '-0.031', 'Thyrotropes': '-0.021', 'Undifferentiated cells (Pituitary gland)': '0.176', 'Mitotic cells (Spleen)': '-0.024', 'Platelets': '-0.106', 'Erythrocytes': '-0.083', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.375', 'NK-cells (Spleen)': '0.160', 'Amygdala excitatory': '40.1', 'Cerebellar inhibitory': '35.2', 'Cge interneuron': '33.8', 'Deep-layer corticothalamic and 6b': '38.9', 'Deep-layer intratelencephalic': '40.1', 'Deep-layer near-projecting': '38.3', 'Eccentric medium spiny neuron': '40.4', 'Hippocampal ca1-3': '41.0', 'Hippocampal ca4': '37.3', 'Hippocampal dentate gyrus': '37.0', 'Lamp5-lhx6 and chandelier': '34.5', 'Lower rhombic lip': '29.2', 'Mammillary body': '42.1', 'Medium spiny neuron': '41.9', 'Mge interneuron': '35.9', 'Midbrain-derived inhibitory': '31.9', 'Miscellaneous': '38.7', 'Splatter': '30.8', 'Thalamic excitatory': '34.8', 'Upper rhombic lip': '28.3', 'Upper-layer intratelencephalic': '43.8', 'Astrocyte': '32.3', 'Bergmann glia': '28.5', 'Central nervous system macrophage': '35.4', 'Choroid plexus epithelial cell': '43.4', 'Committed oligodendrocyte precursor': '42.1', 'Ependymal cell': '22.9', 'Oligodendrocyte': '36.7', 'Oligodendrocyte precursor cell': '39.2', 'Endothelial cell': '16.0', 'Pericyte': '14.9', 'Vascular associated smooth muscle cell': '14.1', 'Fibroblast': '25.3', 'Leukocyte': '22.3', 'Basophil': '1.4', 'Eosinophil': '0.0', 'Neutrophil': '0.9', 'Classical monocyte': '7.8', 'Non-classical monocyte': '9.9', 'Intermediate monocyte': '4.3', 'T-reg': '3.8', 'GdT-cell': '0.7', 'MAIT T-cell': '4.8', 'Memory CD4 T-cell': '0.3', 'Naive CD4 T-cell': '19.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '21.2', 'Memory B-cell': '0.4', 'Naive B-cell': '18.0', 'Plasmacytoid DC': '4.0', 'Myeloid DC': '5.0', 'NK-cell': '22.2', 'Total PBMC': '3.4', 'Vd2 gdTCR': '4.6', 'Memory CD4 T-cell Th1\\/Th17': '19.7', 'Memory CD4 T-cell Th17': '19.2', 'Memory CD4 T-cell Th2': '20.7', 'Non-Vd2 gdTCR': '5.7', 'Memory CD4 T-cell Th1': '20.4', 'Memory CD4 T-cell TFH': '21.2', 'Terminal effector memory CD4 T-cell': '3.7', 'Central memory CD8 T-cell': '3.9', 'Effector memory CD8 T-cell': '5.7', 'Terminal effector memory CD8 T-cell': '6.4', 'Non-switched memory B-cell': '3.6', 'Plasmablast': '3.2', 'Switched memory B-cell': '4.6', 'Exhausted memory B-cell': '4.6', 'Progenitor cell': '6.0', 'Memory T-reg': '18.1', 'Naive CD4 T-cell activated': '101.4', 'Naive CD8 T-cell activated': '93.6', 'Naive T-reg': '18.2'}
|
7OB9, 7OBA, 7OBB, 7VBA, 7VBB, 7VBC, 8A43
|
{'Adipose Tissue': 8.756795681063123, 'Adrenal Gland': 8.38529457364341, 'Bladder': 10.168380952380952, 'Blood': 4.460677847147471, 'Blood Vessel': 8.544486891385768, 'Brain': 5.026852157456473, 'Breast': 8.688100217864925, 'Cervix Uteri': 10.338894736842104, 'Colon': 7.845731707317073, 'Esophagus': 8.865448442906574, 'Fallopian Tube': 11.27111111111111, 'Heart': 4.121485481997677, 'Kidney': 4.1364752808988765, 'Liver': 3.8091929203539823, 'Lung': 8.50079411764706, 'Muscle': 8.903870485678706, 'Nerve': 11.30175928917609, 'Ovary': 10.225305555555556, 'Pancreas': 3.618665548780488, 'Pituitary': 10.18522261484099, 'Prostate': 9.041481632653062, 'Salivary Gland': 6.073475308641975, 'Skin': 12.539152017689332, 'Small Intestine': 6.7487326203208555, 'Spleen': 7.001717842323651, 'Stomach': 6.552066852367688, 'Testis': 13.341362880886429, 'Thyroid': 9.817865237366004, 'Uterus': 18.48073943661972, 'Vagina': 8.347326923076922}
|
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0.42, 0.22, 0.25, 0.53, 0.79, 0.86, 0.83, 0.91, 0.83, 0.81, 0.96]
| null |
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
|
SCF-LIKE
| null |
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
|
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
|
mono, 6, 11, 48, 63
| null |
UBE2V1, UBE2L3, UBE2L6
| null | null | 78.482559
| 0.425398
| 80.55
| 0.368233
| 146
|
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