E3_UniProtID
string
Sub_UniProtID
string
Reference
string
Source
string
E3_Gene_Name
string
E3_Sequence
string
E3_Species
string
E3_Subcellular_Location
string
E3_HPA_Expression
string
E3_scRNA_Data
string
E3_PDB_IDs
string
E3_GTEx_expression
string
Sub_Gene_Name
string
Sub_Sequence
string
Sub_Species
string
Sub_Subcellular_Location
string
Sub_HPA_Expression
string
Sub_scRNA_Data
string
Sub_PDB_IDs
string
Sub_GTEx_expression
string
E3_Confidence_Scores
string
E3_Relative_SASA
string
Sub_Confidence_Scores
string
Sub_Relative_SASA
string
E3_Type
string
E3_Complex
string
Complex_name
string
Susbtrate_specificity
string
E3_Known_direct_interactions
string
E3_Substrates
string
PolyUb_Lys
string
C/N_end
string
Associated_E2
string
Self_oligomerization
string
Atypical_AA_ubi
string
E3_Confidence_Scores_Avg
float64
E3_Relative_SASA_Avg
float64
Sub_Confidence_Scores_Avg
float64
Sub_Relative_SASA_Avg
float64
ClusterID
int64
O60260
Q8IZ81
33082525, 23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
ELMOD2
MFISLWEFFYGHFFRFWMKWLLRQMTGKCELQRIFDTYVGAQRTHRIENSLTYSKNKVLQKATHVVQSEVDKYVDDIMKEKNINPEKDASFKICMKMCLLQITGYKQLYLDVESVRKRPYDSDNLQHEELLMKLWNLLMPTKKLNARISKQWAEIGFQGDDPKTDFRGMGILGLINLVYFSENYTSEAHQILSRSNHPKLGYSYAIVGINLTEMAYSLLKSEALKFHLYNLVPGIPTMEHFHQFYCYLVYEFDKFWFEEEPESIMYFNLYREKFHEKIKGLLLDCNVALTLKV
Homo sapiens
null
Low tissue specificity
{'Ciliated cells': '34.2', 'Basal respiratory cells': '29.7', 'Club cells': '25.8', 'Ionocytes': '32.0', 'Mucus glandular cells': '17.6', 'Serous glandular cells': '18.4', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '23.1', 'Paneth cells': '13.0', 'Distal enterocytes': '16.6', 'Intestinal goblet cells': '11.7', 'Exocrine glandular cells': '-0.593', 'Basal prostatic cells': '15.3', 'Prostatic glandular cells': '28.1', 'Breast glandular cells': '0.472', 'Breast myoepithelial cells': '0.385', 'Glandular and luminal cells': '15.7', 'Secretory cells': '12.5', 'Basal keratinocytes': '11.7', 'Suprabasal keratinocytes': '15.9', 'Basal squamous epithelial cells': '12.2', 'Squamous epithelial cells': '11.6', 'Alveolar cells type 1': '-0.064', 'Alveolar cells type 2': '0.126', 'Salivary duct cells': '13.4', 'Ductal cells': '0.536', 'Hepatocytes': '0.411', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '0.216', 'Distal tubular cells': '3.1', 'Collecting duct cells': '17.5', 'Mesothelial cells': '0.430', 'Sertoli cells': '0.599', 'Granulosa cells': '13.8', 'Enteroendocrine cells': '13.6', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '0.582', 'Excitatory neurons': '19.5', 'Inhibitory neurons': '14.9', 'Cone photoreceptor cells': '11.9', 'Rod photoreceptor cells': '22.7', 'Bipolar cells': '19.0', 'Horizontal cells': '10.7', 'Astrocytes': '21.4', 'Oligodendrocyte precursor cells': '19.3', 'Oligodendrocytes': '32.9', 'Microglial cells': '18.8', 'Muller glia cells': '13.9', 'Schwann cells': '0.090', 'Spermatogonia': '0.616', 'Spermatocytes': '0.333', 'Early spermatids': '-0.405', 'Late spermatids': '-0.698', 'Oocytes': '30.9', 'Cytotrophoblasts': '22.7', 'Syncytiotrophoblasts': '22.2', 'Extravillous trophoblasts': '9.0', 'Endothelial cells': '13.5', 'Lymphatic endothelial cells': '17.5', 'Cardiomyocytes': '0.575', 'Skeletal myocytes': '-0.198', 'Smooth muscle cells': '12.4', 'Adipocytes': '12.9', 'Melanocytes': '-0.014', 'Fibroblasts': '16.4', 'Peritubular cells': '0.529', 'Endometrial stromal cells': '22.1', 'Ovarian stromal cells': '9.9', 'Undifferentiated cells': '12.5', 'T-cells': '13.6', 'B-cells': '11.7', 'Plasma cells': '22.8', 'Nk-cells': '14.2', 'Granulocytes': '7.8', 'Monocytes': '12.8', 'Macrophages': '13.5', 'Hofbauer cells': '17.5', 'Kupffer cells': '14.7', 'Dendritic cells': '15.3', 'Langerhans cells': '0.176', 'Erythroid cells': '-0.047', 'Adipocytes (Subcutaneous)': '0.167', 'Adipocytes (Visceral)': '-0.046', 'Breast glandular cells (progenitors)': '0.274', 'Adipocytes (Breast)': '-0.283', 'Colon enterocytes': '0.023', 'Colon enteroendocrine cells': '0.248', 'Enteric glia cells': '0.142', 'Mitotic cells (Colon)': '0.096', 'Mitotic cells (Heart)': '0.504', 'Podocytes': '-0.123', 'Ascending Loop of Henle cells': '0.508', 'Intercalated cells': '-0.035', 'Cholangiocyte': '0.207', 'NK-cells (Liver)': '-0.231', 'Respiratory ciliated cells': '0.112', 'Mitotic cells (Lung)': '0.285', 'NK-cells (Lung)': '-0.104', 'B-cells (Lung)': '-0.105', 'Alpha cells': '0.396', 'Beta cells': '0.204', 'Prostate glandular cells': '0.289', 'Prostate basal glandular cells': '0.384', 'Urothelial cells': '0.110', 'Keratinocyte (other)': '-0.116', 'Keratinocyte (granular)': '-0.221', 'Hair cortex cells': '0.113', 'Inner root sheath cells': '0.118', 'Outer root sheath cells': '0.279', 'Sebaceous gland cells': '0.338', 'Eccrine sweat gland cells': '0.204', 'Adipocytes (Skin)': '0.215', 'Mitotic cells (Skin)': '0.221', 'Parietal cells': '-0.297', 'Chief cells': '-0.175', 'Gastric mucous cells': '-0.113', 'Gastric enteroendocrine cells': '-0.075', 'Mitotic cells (Stomach)': '0.196', 'Parafollicular cells': '0.083', 'Thyroid glandular cells': '0.482', 'Mitotic cells (Thyroid)': '0.055', 'Adrenal cortex cells': '0.612', 'Adrenal medulla cells': '0.028', 'Mitotic cells (Adrenal gland)': '0.373', 'Minor salivary glandular cells': '0.640', 'Minor salivary gland ductal cells': '0.256', 'Minor salivary gland basal cells': '0.246', 'Mitotic cells (Minor salivary gland)': '0.301', 'Adipocytes (Minor salivary gland)': '0.168', 'Somatotropes': '0.183', 'Lactotropes': '0.181', 'Gonadotropes': '0.206', 'Corticotropes': '-0.082', 'Thyrotropes': '0.217', 'Undifferentiated cells (Pituitary gland)': '0.095', 'Mitotic cells (Spleen)': '-0.130', 'Platelets': '-0.002', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.124', 'B-cells (Spleen)': '0.203', 'NK-cells (Spleen)': '0.272', 'Amygdala excitatory': '21.3', 'Cerebellar inhibitory': '43.8', 'Cge interneuron': '19.6', 'Deep-layer corticothalamic and 6b': '22.0', 'Deep-layer intratelencephalic': '20.6', 'Deep-layer near-projecting': '30.2', 'Eccentric medium spiny neuron': '34.6', 'Hippocampal ca1-3': '25.0', 'Hippocampal ca4': '26.7', 'Hippocampal dentate gyrus': '23.2', 'Lamp5-lhx6 and chandelier': '21.8', 'Lower rhombic lip': '36.8', 'Mammillary body': '36.6', 'Medium spiny neuron': '31.0', 'Mge interneuron': '22.3', 'Midbrain-derived inhibitory': '31.0', 'Miscellaneous': '22.5', 'Splatter': '33.5', 'Thalamic excitatory': '39.0', 'Upper rhombic lip': '45.1', 'Upper-layer intratelencephalic': '21.2', 'Astrocyte': '45.8', 'Bergmann glia': '56.2', 'Central nervous system macrophage': '52.2', 'Choroid plexus epithelial cell': '49.3', 'Committed oligodendrocyte precursor': '35.6', 'Ependymal cell': '68.8', 'Oligodendrocyte': '55.0', 'Oligodendrocyte precursor cell': '38.4', 'Endothelial cell': '34.0', 'Pericyte': '38.1', 'Vascular associated smooth muscle cell': '29.2', 'Fibroblast': '39.9', 'Leukocyte': '37.4', 'Basophil': '36.1', 'Eosinophil': '8.1', 'Neutrophil': '32.2', 'Classical monocyte': '6.3', 'Non-classical monocyte': '11.7', 'Intermediate monocyte': '15.7', 'T-reg': '24.5', 'GdT-cell': '6.6', 'MAIT T-cell': '20.9', 'Memory CD4 T-cell': '5.8', 'Naive CD4 T-cell': '16.5', 'Memory CD8 T-cell': '7.2', 'Naive CD8 T-cell': '14.6', 'Memory B-cell': '3.2', 'Naive B-cell': '17.3', 'Plasmacytoid DC': '40.5', 'Myeloid DC': '14.6', 'NK-cell': '14.9', 'Total PBMC': '21.0', 'Vd2 gdTCR': '20.8', 'Memory CD4 T-cell Th1\\/Th17': '16.2', 'Memory CD4 T-cell Th17': '10.5', 'Memory CD4 T-cell Th2': '12.8', 'Non-Vd2 gdTCR': '20.7', 'Memory CD4 T-cell Th1': '11.2', 'Memory CD4 T-cell TFH': '10.8', 'Terminal effector memory CD4 T-cell': '27.7', 'Central memory CD8 T-cell': '18.5', 'Effector memory CD8 T-cell': '24.9', 'Terminal effector memory CD8 T-cell': '27.2', 'Non-switched memory B-cell': '19.0', 'Plasmablast': '32.3', 'Switched memory B-cell': '12.2', 'Exhausted memory B-cell': '16.7', 'Progenitor cell': '30.5', 'Memory T-reg': '10.1', 'Naive CD4 T-cell activated': '9.1', 'Naive CD8 T-cell activated': '7.7', 'Naive T-reg': '21.3'}
null
{'Adipose Tissue': 8.023902491694352, 'Adrenal Gland': 11.420131782945738, 'Bladder': 9.847666666666663, 'Blood': 4.024989343379978, 'Blood Vessel': 10.453342322097376, 'Brain': 5.137745117335352, 'Breast': 9.284605664488016, 'Cervix Uteri': 13.34084210526316, 'Colon': 8.444431322207958, 'Esophagus': 8.293770934256056, 'Fallopian Tube': 12.896333333333336, 'Heart': 4.346919976771196, 'Kidney': 4.933977528089888, 'Liver': 5.616853982300886, 'Lung': 8.89901730103806, 'Muscle': 2.8993120797011205, 'Nerve': 16.93097899838449, 'Ovary': 11.062061111111111, 'Pancreas': 5.063923780487805, 'Pituitary': 12.60779151943463, 'Prostate': 10.364228571428573, 'Salivary Gland': 8.740463580246914, 'Skin': 9.92581592039801, 'Small Intestine': 10.42924064171123, 'Spleen': 8.35509958506224, 'Stomach': 7.258080779944289, 'Testis': 9.11217728531856, 'Thyroid': 12.233151607963244, 'Uterus': 14.217218309859154, 'Vagina': 10.168679487179489}
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[58.73, 56.02, 60.86, 68.97, 65.95, 67.04, 67.22, 69.38, 66.18, 70.8, 66.6, 68.2, 71.83, 79.55, 77.96, 79.14, 81.1, 83.21, 82.82, 83.96, 86.22, 84.9, 86.28, 82.66, 85.61, 86.13, 88.63, 90.53, 92.66, 93.71, 96.15, 95.29, 94.64, 95.93, 94.78, 92.22, 94.62, 95.58, 94.45, 94.56, 96.62, 96.76, 96.61, 97.46, 97.04, 97.59, 97.63, 97.72, 97.0, 96.84, 97.62, 96.25, 94.01, 94.04, 91.86, 95.09, 95.94, 96.21, 97.0, 96.83, 97.06, 97.31, 95.9, 94.8, 93.72, 93.59, 91.62, 94.17, 96.29, 96.65, 96.6, 97.35, 97.51, 97.52, 96.95, 97.54, 97.71, 96.83, 96.48, 95.96, 93.88, 93.78, 93.61, 91.92, 88.86, 87.85, 89.43, 90.4, 91.67, 92.9, 94.58, 95.39, 94.29, 94.82, 96.64, 96.51, 96.27, 97.13, 97.5, 97.61, 97.61, 97.51, 96.94, 97.22, 97.9, 96.36, 96.91, 98.36, 98.45, 97.96, 98.45, 98.83, 98.52, 98.4, 98.54, 98.22, 97.78, 97.88, 97.7, 98.0, 97.19, 96.64, 97.09, 97.95, 97.89, 98.11, 98.18, 98.07, 98.32, 98.36, 98.36, 97.95, 98.37, 98.71, 98.51, 98.03, 98.56, 98.43, 97.58, 96.32, 95.55, 95.79, 94.71, 95.18, 94.62, 96.03, 95.98, 96.91, 96.98, 96.92, 97.41, 97.84, 96.53, 96.47, 98.07, 97.77, 97.93, 94.16, 93.01, 96.03, 96.7, 97.36, 96.05, 93.12, 96.7, 96.06, 90.67, 91.97, 97.63, 97.37, 98.34, 98.78, 98.59, 98.73, 98.85, 98.89, 98.85, 98.86, 98.81, 98.8, 98.7, 98.35, 98.25, 98.35, 98.15, 98.13, 98.39, 98.66, 98.42, 98.11, 98.43, 98.51, 97.69, 97.14, 97.42, 95.93, 95.36, 92.68, 92.95, 95.66, 95.45, 97.18, 97.14, 98.36, 98.52, 97.83, 97.93, 98.59, 98.48, 97.99, 98.68, 98.81, 98.39, 98.55, 98.83, 98.79, 98.41, 98.72, 98.69, 98.24, 97.86, 97.54, 98.0, 98.23, 96.88, 97.68, 98.18, 98.28, 97.41, 97.17, 96.59, 96.12, 88.45, 91.58, 96.11, 97.41, 97.69, 98.33, 98.03, 98.43, 98.79, 98.71, 98.45, 98.78, 98.85, 98.8, 98.74, 98.8, 98.65, 98.45, 98.38, 98.45, 98.09, 97.5, 98.18, 98.01, 97.04, 97.55, 97.14, 96.33, 94.7, 91.65, 91.31, 91.63, 92.4, 94.67, 95.39, 95.61, 97.36, 97.73, 97.6, 98.05, 98.27, 98.64, 98.51, 98.25, 98.38, 98.61, 97.95, 98.11, 98.18, 98.14, 95.63, 96.25, 94.49, 95.54, 96.13, 95.84, 97.58, 95.58, 95.92, 90.3, 84.07]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
94.614198
0.322253
2,409
O60260
Q8NBU5
33082525
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
ATAD1
MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDPTRKQKVEAQKQAEKLMKQIGVKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDEDEIRPVQQQDLHRAIEKMKKSKDAAFQNVLTHVCLD
Homo sapiens
Mitochondrion outer membrane, Peroxisome membrane, Postsynaptic cell membrane
Low tissue specificity
{'Ciliated cells': '28.0', 'Basal respiratory cells': '46.3', 'Club cells': '37.8', 'Ionocytes': '44.5', 'Mucus glandular cells': '24.3', 'Serous glandular cells': '21.5', 'Gastric mucus-secreting cells': '34.8', 'Proximal enterocytes': '21.4', 'Paneth cells': '18.6', 'Distal enterocytes': '36.3', 'Intestinal goblet cells': '25.6', 'Exocrine glandular cells': '-0.581', 'Basal prostatic cells': '28.0', 'Prostatic glandular cells': '42.3', 'Breast glandular cells': '0.453', 'Breast myoepithelial cells': '0.610', 'Glandular and luminal cells': '30.9', 'Secretory cells': '35.3', 'Basal keratinocytes': '27.0', 'Suprabasal keratinocytes': '26.4', 'Basal squamous epithelial cells': '41.7', 'Squamous epithelial cells': '35.0', 'Alveolar cells type 1': '0.242', 'Alveolar cells type 2': '-0.137', 'Salivary duct cells': '26.9', 'Ductal cells': '0.615', 'Hepatocytes': '0.266', 'Cholangiocytes': '28.6', 'Proximal tubular cells': '0.118', 'Distal tubular cells': '18.4', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.436', 'Sertoli cells': '-0.468', 'Granulosa cells': '31.8', 'Enteroendocrine cells': '23.5', 'Pancreatic endocrine cells': '23.8', 'Leydig cells': '-0.476', 'Excitatory neurons': '66.7', 'Inhibitory neurons': '70.1', 'Cone photoreceptor cells': '69.7', 'Rod photoreceptor cells': '47.4', 'Bipolar cells': '45.6', 'Horizontal cells': '45.3', 'Astrocytes': '44.0', 'Oligodendrocyte precursor cells': '55.2', 'Oligodendrocytes': '49.1', 'Microglial cells': '35.8', 'Muller glia cells': '53.7', 'Schwann cells': '0.169', 'Spermatogonia': '-0.247', 'Spermatocytes': '0.060', 'Early spermatids': '0.710', 'Late spermatids': '0.678', 'Oocytes': '47.8', 'Cytotrophoblasts': '36.8', 'Syncytiotrophoblasts': '100.0', 'Extravillous trophoblasts': '35.2', 'Endothelial cells': '19.2', 'Lymphatic endothelial cells': '23.4', 'Cardiomyocytes': '0.710', 'Skeletal myocytes': '-0.139', 'Smooth muscle cells': '36.0', 'Adipocytes': '31.5', 'Melanocytes': '0.166', 'Fibroblasts': '35.5', 'Peritubular cells': '-0.348', 'Endometrial stromal cells': '41.4', 'Ovarian stromal cells': '23.4', 'Undifferentiated cells': '26.0', 'T-cells': '40.8', 'B-cells': '38.5', 'Plasma cells': '30.5', 'Nk-cells': '32.1', 'Granulocytes': '25.6', 'Monocytes': '41.8', 'Macrophages': '25.1', 'Hofbauer cells': '24.3', 'Kupffer cells': '17.0', 'Dendritic cells': '36.6', 'Langerhans cells': '0.171', 'Erythroid cells': '0.010', 'Adipocytes (Subcutaneous)': '-0.115', 'Adipocytes (Visceral)': '-0.275', 'Breast glandular cells (progenitors)': '0.365', 'Adipocytes (Breast)': '-0.527', 'Colon enterocytes': '-0.246', 'Colon enteroendocrine cells': '0.375', 'Enteric glia cells': '0.262', 'Mitotic cells (Colon)': '-0.101', 'Mitotic cells (Heart)': '0.413', 'Podocytes': '-0.051', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '0.059', 'Cholangiocyte': '0.320', 'NK-cells (Liver)': '-0.236', 'Respiratory ciliated cells': '0.060', 'Mitotic cells (Lung)': '-0.081', 'NK-cells (Lung)': '0.214', 'B-cells (Lung)': '0.042', 'Alpha cells': '0.422', 'Beta cells': '0.249', 'Prostate glandular cells': '-0.045', 'Prostate basal glandular cells': '0.038', 'Urothelial cells': '-0.034', 'Keratinocyte (other)': '0.197', 'Keratinocyte (granular)': '-0.324', 'Hair cortex cells': '0.012', 'Inner root sheath cells': '0.136', 'Outer root sheath cells': '0.286', 'Sebaceous gland cells': '0.042', 'Eccrine sweat gland cells': '0.105', 'Adipocytes (Skin)': '-0.169', 'Mitotic cells (Skin)': '0.391', 'Parietal cells': '-0.492', 'Chief cells': '-0.488', 'Gastric mucous cells': '-0.346', 'Gastric enteroendocrine cells': '-0.339', 'Mitotic cells (Stomach)': '0.006', 'Parafollicular cells': '0.187', 'Thyroid glandular cells': '0.504', 'Mitotic cells (Thyroid)': '-0.028', 'Adrenal cortex cells': '0.602', 'Adrenal medulla cells': '0.062', 'Mitotic cells (Adrenal gland)': '0.278', 'Minor salivary glandular cells': '0.491', 'Minor salivary gland ductal cells': '0.247', 'Minor salivary gland basal cells': '0.405', 'Mitotic cells (Minor salivary gland)': '0.382', 'Adipocytes (Minor salivary gland)': '0.294', 'Somatotropes': '0.116', 'Lactotropes': '0.096', 'Gonadotropes': '0.194', 'Corticotropes': '-0.146', 'Thyrotropes': '0.171', 'Undifferentiated cells (Pituitary gland)': '0.103', 'Mitotic cells (Spleen)': '-0.106', 'Platelets': '-0.231', 'Erythrocytes': '-0.119', 'Hematopoietic stem cells': '-0.285', 'B-cells (Spleen)': '0.341', 'NK-cells (Spleen)': '0.305', 'Amygdala excitatory': '90.0', 'Cerebellar inhibitory': '118.4', 'Cge interneuron': '90.4', 'Deep-layer corticothalamic and 6b': '87.3', 'Deep-layer intratelencephalic': '86.2', 'Deep-layer near-projecting': '93.9', 'Eccentric medium spiny neuron': '101.2', 'Hippocampal ca1-3': '95.4', 'Hippocampal ca4': '90.5', 'Hippocampal dentate gyrus': '86.9', 'Lamp5-lhx6 and chandelier': '107.0', 'Lower rhombic lip': '130.9', 'Mammillary body': '142.5', 'Medium spiny neuron': '102.9', 'Mge interneuron': '102.5', 'Midbrain-derived inhibitory': '104.1', 'Miscellaneous': '88.0', 'Splatter': '104.2', 'Thalamic excitatory': '108.1', 'Upper rhombic lip': '96.1', 'Upper-layer intratelencephalic': '95.0', 'Astrocyte': '77.9', 'Bergmann glia': '82.8', 'Central nervous system macrophage': '87.7', 'Choroid plexus epithelial cell': '130.2', 'Committed oligodendrocyte precursor': '76.6', 'Ependymal cell': '80.1', 'Oligodendrocyte': '70.7', 'Oligodendrocyte precursor cell': '90.5', 'Endothelial cell': '69.2', 'Pericyte': '144.5', 'Vascular associated smooth muscle cell': '82.6', 'Fibroblast': '86.8', 'Leukocyte': '99.3', 'Basophil': '20.4', 'Eosinophil': '4.9', 'Neutrophil': '10.0', 'Classical monocyte': '13.3', 'Non-classical monocyte': '36.8', 'Intermediate monocyte': '24.1', 'T-reg': '34.2', 'GdT-cell': '6.4', 'MAIT T-cell': '37.8', 'Memory CD4 T-cell': '7.3', 'Naive CD4 T-cell': '55.3', 'Memory CD8 T-cell': '8.3', 'Naive CD8 T-cell': '47.4', 'Memory B-cell': '7.3', 'Naive B-cell': '45.6', 'Plasmacytoid DC': '41.0', 'Myeloid DC': '23.1', 'NK-cell': '49.3', 'Total PBMC': '25.3', 'Vd2 gdTCR': '34.4', 'Memory CD4 T-cell Th1\\/Th17': '48.2', 'Memory CD4 T-cell Th17': '40.4', 'Memory CD4 T-cell Th2': '45.5', 'Non-Vd2 gdTCR': '35.5', 'Memory CD4 T-cell Th1': '39.5', 'Memory CD4 T-cell TFH': '44.0', 'Terminal effector memory CD4 T-cell': '42.8', 'Central memory CD8 T-cell': '42.0', 'Effector memory CD8 T-cell': '45.2', 'Terminal effector memory CD8 T-cell': '37.2', 'Non-switched memory B-cell': '28.1', 'Plasmablast': '33.2', 'Switched memory B-cell': '31.1', 'Exhausted memory B-cell': '24.9', 'Progenitor cell': '26.9', 'Memory T-reg': '33.4', 'Naive CD4 T-cell activated': '71.9', 'Naive CD8 T-cell activated': '70.3', 'Naive T-reg': '64.1'}
7UPR, 7UPT
{'Adipose Tissue': 21.19896843853821, 'Adrenal Gland': 18.65125581395349, 'Bladder': 23.380000000000003, 'Blood': 11.916553175457482, 'Blood Vessel': 30.055317602996254, 'Brain': 18.933970476911433, 'Breast': 22.80044226579521, 'Cervix Uteri': 28.11947368421053, 'Colon': 22.17009242618742, 'Esophagus': 20.349654671280277, 'Fallopian Tube': 24.62444444444445, 'Heart': 21.0749393728223, 'Kidney': 11.217865168539326, 'Liver': 9.260690265486726, 'Lung': 23.599837370242216, 'Muscle': 21.760417185554175, 'Nerve': 30.97218093699515, 'Ovary': 26.715444444444444, 'Pancreas': 7.219536585365853, 'Pituitary': 20.602452296819788, 'Prostate': 23.7011387755102, 'Salivary Gland': 18.10845061728395, 'Skin': 23.05710558319514, 'Small Intestine': 17.19175401069519, 'Spleen': 13.997663900414937, 'Stomach': 14.867245125348193, 'Testis': 57.36038781163435, 'Thyroid': 25.76275650842267, 'Uterus': 30.538028169014083, 'Vagina': 24.988205128205127}
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[42.16, 44.54, 45.1, 53.43, 48.44, 51.48, 51.89, 55.41, 62.39, 69.2, 70.5, 78.19, 79.68, 83.7, 82.57, 83.3, 84.22, 85.97, 84.62, 87.57, 89.56, 87.08, 89.45, 90.77, 90.85, 91.32, 91.32, 91.81, 92.23, 90.1, 90.65, 90.21, 88.33, 88.2, 83.77, 84.02, 84.56, 78.83, 76.46, 76.57, 76.17, 71.25, 71.01, 72.75, 72.43, 73.97, 73.4, 71.8, 75.97, 79.04, 72.36, 74.27, 78.79, 77.42, 73.46, 77.12, 78.99, 76.29, 76.05, 76.42, 73.77, 71.82, 70.63, 70.72, 64.57, 66.14, 75.34, 80.33, 83.37, 86.09, 82.93, 84.98, 87.57, 82.49, 81.54, 84.5, 84.43, 77.63, 80.27, 79.97, 75.69, 68.58, 65.62, 65.19, 72.19, 78.49, 84.21, 89.04, 90.28, 92.13, 91.52, 91.27, 93.34, 93.49, 89.76, 92.5, 92.04, 93.03, 94.72, 95.13, 95.48, 94.69, 95.07, 94.68, 93.2, 92.6, 93.03, 93.25, 92.97, 90.71, 91.08, 90.89, 89.52, 85.95, 87.57, 87.48, 84.39, 77.72, 81.65, 84.44, 80.83, 83.31, 84.2, 84.23, 87.35, 91.38, 91.91, 94.75, 96.42, 96.89, 97.31, 96.68, 95.42, 94.34, 93.75, 93.14, 94.42, 92.98, 95.24, 92.22, 92.95, 94.56, 94.04, 93.31, 93.55, 94.28, 93.19, 92.09, 91.78, 91.27, 89.2, 90.87, 90.81, 92.53, 92.36, 91.2, 90.72, 84.54, 79.67, 78.64, 78.4, 76.72, 69.26, 62.69, 54.32, 55.41, 57.31, 69.51, 77.9, 79.03, 83.09, 87.18, 86.09, 87.83, 90.27, 90.97, 92.49, 93.37, 92.65, 91.43, 92.72, 91.97, 89.77, 88.68, 89.11, 91.39, 92.94, 94.99, 95.15, 95.44, 94.09, 91.95, 90.13, 91.16, 88.22, 83.2, 78.07, 77.83, 71.99, 62.99, 59.42, 57.7, 56.61, 61.64, 66.06, 74.7, 78.28, 75.11, 77.29, 79.42, 81.7, 82.04, 82.73, 85.26, 88.4, 89.2, 88.41, 90.47, 91.43, 91.43, 88.16, 86.02, 84.68, 75.62, 77.15, 80.92, 76.1, 80.57, 86.52, 89.85, 94.17, 94.81, 95.55, 96.49, 95.8, 95.89, 94.98, 94.73, 91.74, 91.32, 90.93, 89.52, 88.06, 84.08, 87.62, 86.97, 88.77, 90.49, 90.33, 91.86, 93.08, 91.15, 94.41, 95.7, 96.73, 95.77, 95.69, 93.08, 93.71, 96.12, 96.28, 97.32, 96.62, 96.77, 97.55, 97.27, 96.64, 96.81, 97.48, 96.81, 96.03, 95.86, 96.02, 93.71, 90.98, 94.47, 94.03, 95.32, 95.23, 93.65, 94.17, 95.97, 96.59, 96.95, 97.14, 96.8, 97.3, 97.53, 97.26, 96.39, 96.14, 94.48, 92.72, 95.72, 95.72, 95.34, 95.41, 96.58, 97.18, 96.7, 96.64, 96.57, 97.36, 96.95, 96.3, 97.0, 95.92, 95.15, 94.43, 93.72, 92.91, 91.73, 90.55, 88.66, 88.78, 87.82, 83.26, 72.87, 61.72, 59.76, 56.89, 52.2, 55.06, 58.83, 63.23, 72.92, 82.97, 89.57, 93.04, 95.39, 96.68, 96.64, 96.64, 96.4, 96.77, 97.11, 96.46, 95.82, 96.63, 96.42, 95.25, 94.1, 93.18, 91.98, 89.91, 88.33, 83.12, 81.99, 79.68, 76.91, 72.42, 63.3, 61.71, 64.51, 57.86, 55.09, 56.52, 54.96, 55.52, 49.41, 36.19]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
84.776233
0.387313
2,128
O60260
Q8NG31
33082525
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
KNL1
MDGVSSEANEENDNIERPVRRRHSSILKPPRSPLQDLRGGNERVQESNALRNKKNSRRVSFADTIKVFQTESHMKIVRKSEMEGCSAMVPSQLQLLPPGFKRFSCLSLPETETGENLLLIQNKKLEDNYCEITGMNTLLSAPIHTQMQQKEFSIIEHTRERKHANDQTVIFSDENQMDLTSSHTVMITKGLLDNPISEKSTKIDTTSFLANLKLHTEDSRMKKEVNFSVDQNTSSENKIDFNDFIKRLKTGKCSAFPDVPDKENFEIPIYSKEPNSASSTHQMHVSLKEDENNSNITRLFREKDDGMNFTQCHTANIQTLIPTSSETNSRESKGNDITIYGNDFMDLTFNHTLQILPATGNFSEIENQTQNAMDVTTGYGTKASGNKTVFKSKQNTAFQDLSINSADKIHITRSHIMGAETHIVSQTCNQDARILAMTPESIYSNPSIQGCKTVFYSSCNDAMEMTKCLSNMREEKNLLKHDSNYAKMYCNPDAMSSLTEKTIYSGEENMDITKSHTVAIDNQIFKQDQSNVQIAAAPTPEKEMMLQNLMTTSEDGKMNVNCNSVPHVSKERIQQSLSNPLSISLTDRKTELLSGENMDLTESHTSNLGSQVPLAAYNLAPESTSESHSQSKSSSDECEEITKSRNEPFQRSDIIAKNSLTDTWNKDKDWVLKILPYLDKDSPQSADCNQEIATSHNIVYCGGVLDKQITNRNTVSWEQSLFSTTKPLFSSGQFSMKNHDTAISSHTVKSVLGQNSKLAEPLRKSLSNPTPDYCHDKMIICSEEEQNMDLTKSHTVVIGFGPSELQELGKTNLEHTTGQLTTMNRQIAVKVEKCGKSPIEKSGVLKSNCIMDVLEDESVQKPKFPKEKQNVKIWGRKSVGGPKIDKTIVFSEDDKNDMDITKSYTIEINHRPLLEKRDCHLVPLAGTSETILYTCRQDDMEITRSHTTALECKTVSPDEITTRPMDKTVVFVDNHVELEMTESHTVFIDYQEKERTDRPNFELSQRKSLGTPTVICTPTEESVFFPGNGESDRLVANDSQLTPLEEWSNNRGPVEVADNMELSKSATCKNIKDVQSPGFLNEPLSSKSQRRKSLKLKNDKTIVFSENHKNDMDITQSCMVEIDNESALEDKEDFHLAGASKTILYSCGQDDMEITRSHTTALECKTLLPNEIAIRPMDKTVLFTDNYSDLEVTDSHTVFIDCQATEKILEENPKFGIGKGKNLGVSFPKDNSCVQEIAEKQALAVGNKIVLHTEQKQQLFAATNRTTNEIIKFHSAAMDEKVIGKVVDQACTLEKAQVESCQLNNRDRRNVDFTSSHATAVCGSSDNYSCLPNVISCTDNLEGSAMLLCDKDEEKANYCPVQNDLAYANDFASEYYLESEGQPLSAPCPLLEKEEVIQTSTKGQLDCVITLHKDQDLIKDPRNLLANQTLVYSQDLGEMTKLNSKRVSFKLPKDQMKVYVDDIYVIPQPHFSTDQPPLPKKGQSSINKEEVILSKAGNKSLNIIENSSAPICENKPKILNSEEWFAAACKKELKENIQTTNYNTALDFHSNSDVTKQVIQTHVNAGEAPDPVITSNVPCFHSIKPNLNNLNGKTGEFLAFQTVHLPPLPEQLLELGNKAHNDMHIVQATEIHNINIISSNAKDSRDEENKKSHNGAETTSLPPKTVFKDKVRRCSLGIFLPRLPNKRNCSVTGIDDLEQIPADTTDINHLETQPVSSKDSGIGSVAGKLNLSPSQYINEENLPVYPDEINSSDSINIETEEKALIETYQKEISPYENKMGKTCNSQKRTWVQEEEDIHKEKKIRKNEIKFSDTTQDREIFDHHTEEDIDKSANSVLIKNLSRTPSSCSSSLDSIKADGTSLDFSTYRSSQMESQFLRDTICEESLREKLQDGRITIREFFILLQVHILIQKPRQSNLPGNFTVNTPPTPEDLMLSQYVYRPKIQIYREDCEARRQKIEELKLSASNQDKLLVDINKNLWEKMRHCSDKELKAFGIYLNKIKSCFTKMTKVFTHQGKVALYGKLVQSAQNEREKLQIKIDEMDKILKKIDNCLTEMETETKNLEDEEKNNPVEEWDSEMRAAEKELEQLKTEEEELQRNLLELEVQKEQTLAQIDFMQKQRNRTEELLDQLSLSEWDVVEWSDDQAVFTFVYDTIQLTITFEESVVGFPFLDKRYRKIVDVNFQSLLDEDQAPPSSLLVHKLIFQYVEEKESWKKTCTTQHQLPKMLEEFSLVVHHCRLLGEEIEYLKRWGPNYNLMNIDINNNELRLLFSSSAAFAKFEITLFLSAYYPSVPLPSTIQNHVGNTSQDDIATILSKVPLENNYLKNVVKQIYQDLFQDCHFYH
Homo sapiens
Nucleus, Chromosome, centromere, kinetochore
Group enriched (bone marrow, lymphoid tissue, testis)
{'Ciliated cells': '1.9', 'Basal respiratory cells': '1.8', 'Club cells': '2.0', 'Ionocytes': '1.5', 'Mucus glandular cells': '1.8', 'Serous glandular cells': '2.4', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '24.0', 'Paneth cells': '3.8', 'Distal enterocytes': '0.7', 'Intestinal goblet cells': '3.6', 'Exocrine glandular cells': '-0.307', 'Basal prostatic cells': '0.3', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.209', 'Breast myoepithelial cells': '0.163', 'Glandular and luminal cells': '2.6', 'Secretory cells': '0.7', 'Basal keratinocytes': '7.2', 'Suprabasal keratinocytes': '2.0', 'Basal squamous epithelial cells': '3.1', 'Squamous epithelial cells': '10.1', 'Alveolar cells type 1': '-0.185', 'Alveolar cells type 2': '0.096', 'Salivary duct cells': '2.4', 'Ductal cells': '0.545', 'Hepatocytes': '0.658', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.552', 'Distal tubular cells': '3.1', 'Collecting duct cells': '0.0', 'Mesothelial cells': '-0.018', 'Sertoli cells': '-0.003', 'Granulosa cells': '3.5', 'Enteroendocrine cells': '0.8', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.002', 'Excitatory neurons': '1.2', 'Inhibitory neurons': '1.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.4', 'Bipolar cells': '0.6', 'Horizontal cells': '0.0', 'Astrocytes': '0.3', 'Oligodendrocyte precursor cells': '1.9', 'Oligodendrocytes': '1.0', 'Microglial cells': '2.7', 'Muller glia cells': '0.4', 'Schwann cells': '0.110', 'Spermatogonia': '0.482', 'Spermatocytes': '0.927', 'Early spermatids': '0.381', 'Late spermatids': '-0.018', 'Oocytes': '37.5', 'Cytotrophoblasts': '8.8', 'Syncytiotrophoblasts': '3.0', 'Extravillous trophoblasts': '11.8', 'Endothelial cells': '1.6', 'Lymphatic endothelial cells': '0.2', 'Cardiomyocytes': '0.340', 'Skeletal myocytes': '-0.017', 'Smooth muscle cells': '1.7', 'Adipocytes': '0.2', 'Melanocytes': '0.489', 'Fibroblasts': '1.4', 'Peritubular cells': '-0.076', 'Endometrial stromal cells': '2.4', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '14.8', 'T-cells': '4.5', 'B-cells': '4.6', 'Plasma cells': '21.7', 'Nk-cells': '4.1', 'Granulocytes': '2.2', 'Monocytes': '2.6', 'Macrophages': '5.0', 'Hofbauer cells': '6.1', 'Kupffer cells': '3.6', 'Dendritic cells': '1.2', 'Langerhans cells': '0.215', 'Erythroid cells': '0.061', 'Adipocytes (Subcutaneous)': '-0.023', 'Adipocytes (Visceral)': '-0.054', 'Breast glandular cells (progenitors)': '0.088', 'Adipocytes (Breast)': '-0.077', 'Colon enterocytes': '0.348', 'Colon enteroendocrine cells': '-0.098', 'Enteric glia cells': '-0.178', 'Mitotic cells (Colon)': '0.712', 'Mitotic cells (Heart)': '0.762', 'Podocytes': '0.149', 'Ascending Loop of Henle cells': '0.122', 'Intercalated cells': '0.294', 'Cholangiocyte': '0.057', 'NK-cells (Liver)': '0.145', 'Respiratory ciliated cells': '0.034', 'Mitotic cells (Lung)': '0.859', 'NK-cells (Lung)': '0.018', 'B-cells (Lung)': '0.109', 'Alpha cells': '0.182', 'Beta cells': '0.101', 'Prostate glandular cells': '-0.068', 'Prostate basal glandular cells': '0.352', 'Urothelial cells': '0.390', 'Keratinocyte (other)': '0.263', 'Keratinocyte (granular)': '-0.209', 'Hair cortex cells': '0.062', 'Inner root sheath cells': '0.190', 'Outer root sheath cells': '0.235', 'Sebaceous gland cells': '0.114', 'Eccrine sweat gland cells': '-0.011', 'Adipocytes (Skin)': '-0.157', 'Mitotic cells (Skin)': '0.887', 'Parietal cells': '0.185', 'Chief cells': '0.098', 'Gastric mucous cells': '0.605', 'Gastric enteroendocrine cells': '0.217', 'Mitotic cells (Stomach)': '0.926', 'Parafollicular cells': '0.031', 'Thyroid glandular cells': '0.083', 'Mitotic cells (Thyroid)': '0.564', 'Adrenal cortex cells': '0.445', 'Adrenal medulla cells': '0.112', 'Mitotic cells (Adrenal gland)': '0.931', 'Minor salivary glandular cells': '0.192', 'Minor salivary gland ductal cells': '-0.259', 'Minor salivary gland basal cells': '0.682', 'Mitotic cells (Minor salivary gland)': '0.937', 'Adipocytes (Minor salivary gland)': '0.196', 'Somatotropes': '-0.179', 'Lactotropes': '-0.297', 'Gonadotropes': '-0.070', 'Corticotropes': '-0.153', 'Thyrotropes': '-0.081', 'Undifferentiated cells (Pituitary gland)': '0.407', 'Mitotic cells (Spleen)': '0.920', 'Platelets': '0.152', 'Erythrocytes': '0.327', 'Hematopoietic stem cells': '0.350', 'B-cells (Spleen)': '-0.077', 'NK-cells (Spleen)': '-0.129', 'Amygdala excitatory': '1.7', 'Cerebellar inhibitory': '1.5', 'Cge interneuron': '1.4', 'Deep-layer corticothalamic and 6b': '1.0', 'Deep-layer intratelencephalic': '1.3', 'Deep-layer near-projecting': '1.8', 'Eccentric medium spiny neuron': '1.1', 'Hippocampal ca1-3': '1.2', 'Hippocampal ca4': '2.4', 'Hippocampal dentate gyrus': '1.3', 'Lamp5-lhx6 and chandelier': '1.3', 'Lower rhombic lip': '1.8', 'Mammillary body': '1.4', 'Medium spiny neuron': '1.1', 'Mge interneuron': '1.5', 'Midbrain-derived inhibitory': '1.5', 'Miscellaneous': '1.1', 'Splatter': '1.4', 'Thalamic excitatory': '1.7', 'Upper rhombic lip': '0.5', 'Upper-layer intratelencephalic': '1.8', 'Astrocyte': '1.6', 'Bergmann glia': '2.7', 'Central nervous system macrophage': '2.6', 'Choroid plexus epithelial cell': '0.4', 'Committed oligodendrocyte precursor': '1.7', 'Ependymal cell': '1.3', 'Oligodendrocyte': '1.1', 'Oligodendrocyte precursor cell': '1.7', 'Endothelial cell': '1.1', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.7', 'Fibroblast': '0.8', 'Leukocyte': '4.8', 'Basophil': '7.9', 'Eosinophil': '0.0', 'Neutrophil': '0.9', 'Classical monocyte': '0.3', 'Non-classical monocyte': '1.9', 'Intermediate monocyte': '2.1', 'T-reg': '8.7', 'GdT-cell': '0.0', 'MAIT T-cell': '1.3', 'Memory CD4 T-cell': '0.2', 'Naive CD4 T-cell': '0.3', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.2', 'Memory B-cell': '0.7', 'Naive B-cell': '4.9', 'Plasmacytoid DC': '1.7', 'Myeloid DC': '1.2', 'NK-cell': '1.3', 'Total PBMC': '2.4', 'Vd2 gdTCR': '1.7', 'Memory CD4 T-cell Th1\\/Th17': '0.2', 'Memory CD4 T-cell Th17': '0.5', 'Memory CD4 T-cell Th2': '1.2', 'Non-Vd2 gdTCR': '1.3', 'Memory CD4 T-cell Th1': '0.6', 'Memory CD4 T-cell TFH': '0.4', 'Terminal effector memory CD4 T-cell': '0.2', 'Central memory CD8 T-cell': '2.1', 'Effector memory CD8 T-cell': '4.0', 'Terminal effector memory CD8 T-cell': '0.6', 'Non-switched memory B-cell': '14.1', 'Plasmablast': '7.3', 'Switched memory B-cell': '6.0', 'Exhausted memory B-cell': '3.1', 'Progenitor cell': '2.6', 'Memory T-reg': '3.3', 'Naive CD4 T-cell activated': '0.6', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '0.6'}
3SI5, 4A1G, 4NF9, 4NFA, 8PPR, 8Q5H
{'Adipose Tissue': 0.254155415282392, 'Adrenal Gland': 0.2576515503875969, 'Bladder': 0.2623433333333334, 'Blood': 3.707035878363832, 'Blood Vessel': 0.1814732337078651, 'Brain': 0.0458557831188493, 'Breast': 0.2275272614379085, 'Cervix Uteri': 0.3255073684210526, 'Colon': 0.6315732580231065, 'Esophagus': 1.0305575460207612, 'Fallopian Tube': 0.1426311111111111, 'Heart': 0.0926688675958188, 'Kidney': 0.554176404494382, 'Liver': 0.7269950884955753, 'Lung': 0.7792478892733564, 'Muscle': 0.0326427584059775, 'Nerve': 0.1811484814216478, 'Ovary': 0.2226578888888889, 'Pancreas': 0.0743820670731707, 'Pituitary': 0.1150306360424028, 'Prostate': 0.2277660408163265, 'Salivary Gland': 0.5431427777777778, 'Skin': 3.90834311774461, 'Small Intestine': 1.9478514438502672, 'Spleen': 1.2649414937759338, 'Stomach': 0.5756558440111421, 'Testis': 25.05953739612189, 'Thyroid': 0.3458757120980092, 'Uterus': 0.1547983098591549, 'Vagina': 1.0526970512820513}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
39.70643
0.807848
73
O60260
Q8TB36
33082525, 23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
GDAP1
MAERQEEQRGSPPLRAEGKADAEVKLILYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICEATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPAYATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQVETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVLKRKTFNKVLGHVNNILISAVLPTAFRVAKKRAPKVLGTTLVVGLLAGVGYFAFMLFRKRLGSMILAFRPRPNYF
Homo sapiens
Mitochondrion outer membrane, Cytoplasm
Tissue enhanced (brain)
{'Ciliated cells': '8.6', 'Basal respiratory cells': '5.0', 'Club cells': '5.2', 'Ionocytes': '4.4', 'Mucus glandular cells': '5.2', 'Serous glandular cells': '5.2', 'Gastric mucus-secreting cells': '3.5', 'Proximal enterocytes': '4.2', 'Paneth cells': '3.8', 'Distal enterocytes': '2.0', 'Intestinal goblet cells': '2.3', 'Exocrine glandular cells': '-0.624', 'Basal prostatic cells': '4.8', 'Prostatic glandular cells': '7.2', 'Breast glandular cells': '0.627', 'Breast myoepithelial cells': '0.538', 'Glandular and luminal cells': '3.2', 'Secretory cells': '5.6', 'Basal keratinocytes': '3.3', 'Suprabasal keratinocytes': '3.6', 'Basal squamous epithelial cells': '5.5', 'Squamous epithelial cells': '3.8', 'Alveolar cells type 1': '-0.146', 'Alveolar cells type 2': '0.026', 'Salivary duct cells': '4.3', 'Ductal cells': '0.420', 'Hepatocytes': '0.260', 'Cholangiocytes': '3.8', 'Proximal tubular cells': '0.136', 'Distal tubular cells': '6.1', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.447', 'Sertoli cells': '0.526', 'Granulosa cells': '7.8', 'Enteroendocrine cells': '19.2', 'Pancreatic endocrine cells': '13.6', 'Leydig cells': '0.538', 'Excitatory neurons': '73.1', 'Inhibitory neurons': '64.5', 'Cone photoreceptor cells': '91.8', 'Rod photoreceptor cells': '85.1', 'Bipolar cells': '51.3', 'Horizontal cells': '62.3', 'Astrocytes': '25.7', 'Oligodendrocyte precursor cells': '63.7', 'Oligodendrocytes': '39.0', 'Microglial cells': '14.3', 'Muller glia cells': '24.0', 'Schwann cells': '0.333', 'Spermatogonia': '0.539', 'Spermatocytes': '0.353', 'Early spermatids': '-0.189', 'Late spermatids': '-0.589', 'Oocytes': '16.2', 'Cytotrophoblasts': '0.4', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.2', 'Endothelial cells': '7.2', 'Lymphatic endothelial cells': '15.7', 'Cardiomyocytes': '0.496', 'Skeletal myocytes': '0.133', 'Smooth muscle cells': '6.6', 'Adipocytes': '8.1', 'Melanocytes': '0.000', 'Fibroblasts': '4.5', 'Peritubular cells': '0.479', 'Endometrial stromal cells': '7.9', 'Ovarian stromal cells': '8.3', 'Undifferentiated cells': '3.7', 'T-cells': '4.6', 'B-cells': '5.6', 'Plasma cells': '2.6', 'Nk-cells': '8.0', 'Granulocytes': '12.1', 'Monocytes': '11.1', 'Macrophages': '5.3', 'Hofbauer cells': '5.2', 'Kupffer cells': '5.3', 'Dendritic cells': '2.2', 'Langerhans cells': '0.074', 'Erythroid cells': '0.063', 'Adipocytes (Subcutaneous)': '-0.314', 'Adipocytes (Visceral)': '-0.340', 'Breast glandular cells (progenitors)': '0.360', 'Adipocytes (Breast)': '-0.487', 'Colon enterocytes': '-0.074', 'Colon enteroendocrine cells': '0.664', 'Enteric glia cells': '0.383', 'Mitotic cells (Colon)': '-0.016', 'Mitotic cells (Heart)': '0.457', 'Podocytes': '-0.077', 'Ascending Loop of Henle cells': '0.525', 'Intercalated cells': '0.091', 'Cholangiocyte': '0.360', 'NK-cells (Liver)': '-0.193', 'Respiratory ciliated cells': '0.105', 'Mitotic cells (Lung)': '0.260', 'NK-cells (Lung)': '-0.058', 'B-cells (Lung)': '-0.029', 'Alpha cells': '0.335', 'Beta cells': '0.259', 'Prostate glandular cells': '-0.001', 'Prostate basal glandular cells': '0.298', 'Urothelial cells': '0.125', 'Keratinocyte (other)': '-0.326', 'Keratinocyte (granular)': '-0.395', 'Hair cortex cells': '0.317', 'Inner root sheath cells': '0.347', 'Outer root sheath cells': '0.501', 'Sebaceous gland cells': '0.261', 'Eccrine sweat gland cells': '0.471', 'Adipocytes (Skin)': '0.318', 'Mitotic cells (Skin)': '0.242', 'Parietal cells': '-0.695', 'Chief cells': '-0.567', 'Gastric mucous cells': '-0.533', 'Gastric enteroendocrine cells': '-0.328', 'Mitotic cells (Stomach)': '-0.111', 'Parafollicular cells': '0.208', 'Thyroid glandular cells': '0.537', 'Mitotic cells (Thyroid)': '-0.019', 'Adrenal cortex cells': '0.344', 'Adrenal medulla cells': '0.399', 'Mitotic cells (Adrenal gland)': '0.340', 'Minor salivary glandular cells': '0.399', 'Minor salivary gland ductal cells': '0.170', 'Minor salivary gland basal cells': '0.409', 'Mitotic cells (Minor salivary gland)': '0.399', 'Adipocytes (Minor salivary gland)': '0.295', 'Somatotropes': '0.122', 'Lactotropes': '0.245', 'Gonadotropes': '0.144', 'Corticotropes': '0.420', 'Thyrotropes': '0.384', 'Undifferentiated cells (Pituitary gland)': '-0.181', 'Mitotic cells (Spleen)': '-0.102', 'Platelets': '-0.088', 'Erythrocytes': '-0.106', 'Hematopoietic stem cells': '-0.135', 'B-cells (Spleen)': '0.189', 'NK-cells (Spleen)': '0.234', 'Amygdala excitatory': '683.0', 'Cerebellar inhibitory': '306.3', 'Cge interneuron': '303.8', 'Deep-layer corticothalamic and 6b': '534.7', 'Deep-layer intratelencephalic': '592.0', 'Deep-layer near-projecting': '343.9', 'Eccentric medium spiny neuron': '395.9', 'Hippocampal ca1-3': '757.6', 'Hippocampal ca4': '723.9', 'Hippocampal dentate gyrus': '618.6', 'Lamp5-lhx6 and chandelier': '371.0', 'Lower rhombic lip': '398.0', 'Mammillary body': '745.1', 'Medium spiny neuron': '463.2', 'Mge interneuron': '487.3', 'Midbrain-derived inhibitory': '432.5', 'Miscellaneous': '487.8', 'Splatter': '424.4', 'Thalamic excitatory': '591.5', 'Upper rhombic lip': '299.5', 'Upper-layer intratelencephalic': '533.6', 'Astrocyte': '227.1', 'Bergmann glia': '329.1', 'Central nervous system macrophage': '115.7', 'Choroid plexus epithelial cell': '114.3', 'Committed oligodendrocyte precursor': '289.2', 'Ependymal cell': '185.1', 'Oligodendrocyte': '329.7', 'Oligodendrocyte precursor cell': '567.4', 'Endothelial cell': '66.2', 'Pericyte': '95.8', 'Vascular associated smooth muscle cell': '43.2', 'Fibroblast': '68.8', 'Leukocyte': '39.2', 'Basophil': '7.2', 'Eosinophil': '1.0', 'Neutrophil': '3.4', 'Classical monocyte': '5.1', 'Non-classical monocyte': '18.0', 'Intermediate monocyte': '11.4', 'T-reg': '7.6', 'GdT-cell': '0.8', 'MAIT T-cell': '4.4', 'Memory CD4 T-cell': '0.8', 'Naive CD4 T-cell': '8.9', 'Memory CD8 T-cell': '1.3', 'Naive CD8 T-cell': '9.4', 'Memory B-cell': '1.4', 'Naive B-cell': '15.4', 'Plasmacytoid DC': '3.1', 'Myeloid DC': '4.9', 'NK-cell': '8.6', 'Total PBMC': '5.0', 'Vd2 gdTCR': '4.5', 'Memory CD4 T-cell Th1\\/Th17': '10.0', 'Memory CD4 T-cell Th17': '9.4', 'Memory CD4 T-cell Th2': '9.9', 'Non-Vd2 gdTCR': '4.2', 'Memory CD4 T-cell Th1': '8.6', 'Memory CD4 T-cell TFH': '7.8', 'Terminal effector memory CD4 T-cell': '2.7', 'Central memory CD8 T-cell': '9.4', 'Effector memory CD8 T-cell': '6.6', 'Terminal effector memory CD8 T-cell': '6.9', 'Non-switched memory B-cell': '10.4', 'Plasmablast': '8.3', 'Switched memory B-cell': '9.9', 'Exhausted memory B-cell': '12.0', 'Progenitor cell': '12.7', 'Memory T-reg': '11.9', 'Naive CD4 T-cell activated': '5.1', 'Naive CD8 T-cell activated': '6.9', 'Naive T-reg': '10.4'}
7AIA, 7ALM, 7B2G, 7Q6J, 7Q6K, 7YWD, 8A4J, 8A4K
{'Adipose Tissue': 5.027931810631229, 'Adrenal Gland': 5.921422868217054, 'Bladder': 6.1240000000000006, 'Blood': 1.790861679224973, 'Blood Vessel': 3.966508464419476, 'Brain': 39.441741483724456, 'Breast': 8.512030501089324, 'Cervix Uteri': 7.433631578947368, 'Colon': 4.348704107830552, 'Esophagus': 4.60117107266436, 'Fallopian Tube': 5.7845555555555555, 'Heart': 1.5289376306620208, 'Kidney': 3.1645719101123597, 'Liver': 1.187247787610619, 'Lung': 4.142040311418685, 'Muscle': 2.1206495641344953, 'Nerve': 14.563662358642972, 'Ovary': 13.111761111111113, 'Pancreas': 5.479246951219512, 'Pituitary': 40.58452650176679, 'Prostate': 7.443269387755103, 'Salivary Gland': 4.262043209876543, 'Skin': 3.940176838032062, 'Small Intestine': 4.346363636363637, 'Spleen': 3.614551867219917, 'Stomach': 2.9726431754874647, 'Testis': 10.257473684210526, 'Thyroid': 10.990791730474731, 'Uterus': 8.862429577464788, 'Vagina': 5.894492948717948}
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[0.96, 0.88, 0.94, 0.92, 0.95, 0.93, 0.9, 0.96, 0.94, 0.87, 0.94, 0.96, 0.91, 0.95, 0.93, 0.91, 0.96, 0.93, 0.96, 0.96, 0.92, 0.75, 0.79, 0.53, 0.55, 0.04, 0.19, 0.0, 0.19, 0.02, 0.21, 0.2, 0.08, 0.13, 0.17, 0.34, 0.0, 0.03, 0.05, 0.0, 0.14, 0.0, 0.0, 0.05, 0.22, 0.08, 0.01, 0.67, 0.15, 0.78, 0.25, 0.31, 0.47, 0.33, 0.36, 0.01, 0.04, 0.22, 0.25, 0.28, 0.08, 0.09, 0.16, 0.02, 0.3, 0.21, 0.46, 0.0, 0.02, 0.56, 0.22, 0.05, 0.53, 0.29, 0.02, 0.44, 0.1, 0.03, 0.0, 0.0, 0.16, 0.16, 0.53, 0.95, 0.48, 0.49, 0.11, 0.23, 0.47, 0.09, 0.44, 0.59, 0.0, 0.05, 0.31, 0.23, 0.0, 0.12, 0.72, 0.46, 0.19, 0.52, 0.51, 0.97, 0.91, 0.13, 0.41, 0.52, 0.02, 0.15, 0.26, 0.54, 0.73, 0.93, 0.29, 0.85, 0.42, 0.23, 0.64, 0.24, 0.0, 0.26, 0.54, 0.08, 0.08, 0.57, 0.18, 0.01, 0.27, 0.66, 0.11, 0.26, 0.04, 0.37, 0.03, 0.03, 0.2, 0.34, 0.02, 0.09, 0.05, 0.28, 0.15, 0.46, 0.78, 0.17, 0.19, 0.55, 0.61, 0.4, 0.32, 0.15, 0.33, 0.67, 0.48, 0.06, 0.13, 0.61, 0.43, 0.29, 0.4, 0.49, 0.27, 0.16, 0.67, 0.54, 0.13, 0.46, 0.59, 0.38, 0.01, 0.57, 0.56, 0.15, 0.07, 0.64, 0.61, 0.17, 0.69, 0.75, 0.1, 0.43, 0.83, 0.17, 0.01, 0.51, 0.38, 0.09, 0.25, 0.76, 0.38, 0.25, 0.59, 0.48, 0.4, 0.27, 0.66, 0.44, 0.04, 0.56, 0.45, 0.3, 0.82, 0.35, 0.03, 0.53, 0.59, 0.04, 0.08, 0.48, 0.41, 0.0, 0.19, 0.61, 0.1, 0.0, 0.44, 0.4, 0.0, 0.12, 0.61, 0.1, 0.04, 0.46, 0.55, 0.1, 0.42, 0.71, 0.53, 0.31, 0.75, 0.97, 0.99, 0.46, 0.82, 0.59, 0.09, 0.13, 0.0, 0.01, 0.14, 0.75, 0.67, 0.1, 0.12, 0.02, 0.0, 0.0, 0.01, 0.04, 0.0, 0.0, 0.0, 0.01, 0.0, 0.05, 0.07, 0.0, 0.33, 0.07, 0.0, 0.06, 0.01, 0.17, 0.53, 0.47, 0.02, 0.04, 0.13, 0.75, 0.55, 0.53, 0.03, 0.49, 0.24, 0.0, 0.31, 0.45, 0.03, 0.04, 0.51, 0.22, 0.0, 0.35, 0.77, 0.28, 0.83, 0.2, 0.03, 0.52, 0.81, 0.15, 0.0, 0.51, 0.68, 0.03, 0.24, 0.44, 0.11, 0.55, 0.59, 0.15, 0.13, 0.26, 0.64, 0.38, 0.11, 0.5, 0.68, 0.23, 0.3, 0.53, 0.73, 0.57, 0.79, 0.47, 0.54, 0.89, 0.55, 0.46, 0.52, 0.53, 0.54, 0.59, 0.5, 0.62, 0.53, 0.62, 0.62, 0.58, 0.34, 0.61, 0.45, 0.6, 0.7, 0.51, 0.6, 0.41, 0.63, 0.63, 0.66, 0.71, 0.73, 0.44, 0.34, 0.51, 0.55, 0.62, 0.71, 0.75, 0.81, 0.79, 0.88, 0.93, 0.73, 0.93, 0.89, 0.97]
null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
87.827151
0.38514
2,141
O60260
Q8WUM4
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
PDCD6IP
MATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRRAAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDKGSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAKHYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFLKATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKEVFPVLAAKHCIMQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVKDFSDKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKFTDLFEKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNLPAAIEDVSGDTVPQSILTKSRSVIEQGGIQTVDQLIKELPELLQRNREILDESLRLLDEEEATDNDLRAKFKERWQRTPSNELYKPLRAEGTNFRTVLDKAVQADGQVKECYQSHRDTIVLLCKPEPELNAAIPSANPAKTMQGSEVVNVLKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALSVTELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREEVLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFARKTERDELLKDLQQSIAREPSAPSIPTPAYQSSPAGGHAPTPPTPAPRTMPPTKPQPPARPPPPVLPANRAPSATAPSPVGAGTAAPAPSQTPGSAPPPQAQGPPYPTYPGYPGYCQMPMPMGYNPYAYGQYNMPYPPVYHQSPGQAPYPGPQQPSYPFPQPPQQSYYPQQ
Homo sapiens
Cytoplasm, cytosol, Melanosome, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Secreted, extracellular exosome, Cell junction, tight junction, Midbody, Midbody ring
Low tissue specificity
{'Ciliated cells': '93.3', 'Basal respiratory cells': '60.4', 'Club cells': '65.4', 'Ionocytes': '60.4', 'Mucus glandular cells': '63.2', 'Serous glandular cells': '61.1', 'Gastric mucus-secreting cells': '84.3', 'Proximal enterocytes': '116.9', 'Paneth cells': '75.6', 'Distal enterocytes': '221.4', 'Intestinal goblet cells': '97.8', 'Exocrine glandular cells': '-0.656', 'Basal prostatic cells': '44.8', 'Prostatic glandular cells': '68.7', 'Breast glandular cells': '0.309', 'Breast myoepithelial cells': '0.242', 'Glandular and luminal cells': '74.0', 'Secretory cells': '42.6', 'Basal keratinocytes': '54.3', 'Suprabasal keratinocytes': '74.8', 'Basal squamous epithelial cells': '52.3', 'Squamous epithelial cells': '62.6', 'Alveolar cells type 1': '0.225', 'Alveolar cells type 2': '-0.013', 'Salivary duct cells': '54.1', 'Ductal cells': '0.688', 'Hepatocytes': '0.599', 'Cholangiocytes': '55.3', 'Proximal tubular cells': '0.235', 'Distal tubular cells': '21.5', 'Collecting duct cells': '58.3', 'Mesothelial cells': '0.316', 'Sertoli cells': '0.534', 'Granulosa cells': '52.4', 'Enteroendocrine cells': '63.7', 'Pancreatic endocrine cells': '56.0', 'Leydig cells': '0.480', 'Excitatory neurons': '80.7', 'Inhibitory neurons': '66.3', 'Cone photoreceptor cells': '35.7', 'Rod photoreceptor cells': '48.5', 'Bipolar cells': '28.3', 'Horizontal cells': '26.4', 'Astrocytes': '81.4', 'Oligodendrocyte precursor cells': '90.1', 'Oligodendrocytes': '150.5', 'Microglial cells': '72.5', 'Muller glia cells': '20.7', 'Schwann cells': '0.097', 'Spermatogonia': '0.496', 'Spermatocytes': '0.372', 'Early spermatids': '-0.154', 'Late spermatids': '-0.600', 'Oocytes': '27.2', 'Cytotrophoblasts': '50.9', 'Syncytiotrophoblasts': '107.0', 'Extravillous trophoblasts': '55.4', 'Endothelial cells': '67.5', 'Lymphatic endothelial cells': '145.6', 'Cardiomyocytes': '0.592', 'Skeletal myocytes': '-0.294', 'Smooth muscle cells': '43.2', 'Adipocytes': '69.9', 'Melanocytes': '0.226', 'Fibroblasts': '52.6', 'Peritubular cells': '0.513', 'Endometrial stromal cells': '77.5', 'Ovarian stromal cells': '56.9', 'Undifferentiated cells': '55.2', 'T-cells': '54.4', 'B-cells': '69.8', 'Plasma cells': '37.8', 'Nk-cells': '49.0', 'Granulocytes': '38.7', 'Monocytes': '148.3', 'Macrophages': '84.2', 'Hofbauer cells': '67.0', 'Kupffer cells': '88.9', 'Dendritic cells': '54.2', 'Langerhans cells': '0.311', 'Erythroid cells': '-0.020', 'Adipocytes (Subcutaneous)': '0.093', 'Adipocytes (Visceral)': '-0.142', 'Breast glandular cells (progenitors)': '0.120', 'Adipocytes (Breast)': '-0.103', 'Colon enterocytes': '0.098', 'Colon enteroendocrine cells': '0.223', 'Enteric glia cells': '-0.040', 'Mitotic cells (Colon)': '0.196', 'Mitotic cells (Heart)': '0.555', 'Podocytes': '-0.033', 'Ascending Loop of Henle cells': '0.462', 'Intercalated cells': '0.070', 'Cholangiocyte': '0.409', 'NK-cells (Liver)': '-0.344', 'Respiratory ciliated cells': '0.058', 'Mitotic cells (Lung)': '0.049', 'NK-cells (Lung)': '0.154', 'B-cells (Lung)': '-0.106', 'Alpha cells': '0.415', 'Beta cells': '0.246', 'Prostate glandular cells': '-0.128', 'Prostate basal glandular cells': '0.136', 'Urothelial cells': '0.060', 'Keratinocyte (other)': '0.340', 'Keratinocyte (granular)': '-0.050', 'Hair cortex cells': '-0.034', 'Inner root sheath cells': '0.030', 'Outer root sheath cells': '0.168', 'Sebaceous gland cells': '0.087', 'Eccrine sweat gland cells': '-0.041', 'Adipocytes (Skin)': '-0.074', 'Mitotic cells (Skin)': '0.425', 'Parietal cells': '-0.512', 'Chief cells': '-0.517', 'Gastric mucous cells': '-0.162', 'Gastric enteroendocrine cells': '-0.358', 'Mitotic cells (Stomach)': '0.249', 'Parafollicular cells': '0.116', 'Thyroid glandular cells': '0.482', 'Mitotic cells (Thyroid)': '0.121', 'Adrenal cortex cells': '0.682', 'Adrenal medulla cells': '0.057', 'Mitotic cells (Adrenal gland)': '0.468', 'Minor salivary glandular cells': '0.273', 'Minor salivary gland ductal cells': '-0.143', 'Minor salivary gland basal cells': '0.681', 'Mitotic cells (Minor salivary gland)': '0.715', 'Adipocytes (Minor salivary gland)': '0.223', 'Somatotropes': '-0.012', 'Lactotropes': '-0.100', 'Gonadotropes': '0.111', 'Corticotropes': '-0.200', 'Thyrotropes': '0.114', 'Undifferentiated cells (Pituitary gland)': '0.273', 'Mitotic cells (Spleen)': '-0.300', 'Platelets': '-0.014', 'Erythrocytes': '-0.126', 'Hematopoietic stem cells': '-0.194', 'B-cells (Spleen)': '0.353', 'NK-cells (Spleen)': '0.365', 'Amygdala excitatory': '107.1', 'Cerebellar inhibitory': '88.1', 'Cge interneuron': '81.6', 'Deep-layer corticothalamic and 6b': '114.9', 'Deep-layer intratelencephalic': '106.0', 'Deep-layer near-projecting': '82.4', 'Eccentric medium spiny neuron': '98.4', 'Hippocampal ca1-3': '125.8', 'Hippocampal ca4': '114.6', 'Hippocampal dentate gyrus': '98.2', 'Lamp5-lhx6 and chandelier': '82.4', 'Lower rhombic lip': '159.5', 'Mammillary body': '124.4', 'Medium spiny neuron': '101.8', 'Mge interneuron': '91.2', 'Midbrain-derived inhibitory': '90.9', 'Miscellaneous': '110.7', 'Splatter': '97.1', 'Thalamic excitatory': '114.2', 'Upper rhombic lip': '94.4', 'Upper-layer intratelencephalic': '92.1', 'Astrocyte': '140.8', 'Bergmann glia': '143.7', 'Central nervous system macrophage': '191.5', 'Choroid plexus epithelial cell': '124.2', 'Committed oligodendrocyte precursor': '154.3', 'Ependymal cell': '104.7', 'Oligodendrocyte': '233.9', 'Oligodendrocyte precursor cell': '143.3', 'Endothelial cell': '214.2', 'Pericyte': '116.1', 'Vascular associated smooth muscle cell': '106.2', 'Fibroblast': '124.5', 'Leukocyte': '167.0', 'Basophil': '110.5', 'Eosinophil': '11.0', 'Neutrophil': '90.5', 'Classical monocyte': '70.9', 'Non-classical monocyte': '155.5', 'Intermediate monocyte': '142.4', 'T-reg': '65.6', 'GdT-cell': '8.0', 'MAIT T-cell': '62.8', 'Memory CD4 T-cell': '8.9', 'Naive CD4 T-cell': '70.1', 'Memory CD8 T-cell': '8.1', 'Naive CD8 T-cell': '57.9', 'Memory B-cell': '12.0', 'Naive B-cell': '75.8', 'Plasmacytoid DC': '78.2', 'Myeloid DC': '84.1', 'NK-cell': '59.7', 'Total PBMC': '83.3', 'Vd2 gdTCR': '67.0', 'Memory CD4 T-cell Th1\\/Th17': '69.6', 'Memory CD4 T-cell Th17': '64.9', 'Memory CD4 T-cell Th2': '65.9', 'Non-Vd2 gdTCR': '66.1', 'Memory CD4 T-cell Th1': '59.1', 'Memory CD4 T-cell TFH': '57.7', 'Terminal effector memory CD4 T-cell': '69.7', 'Central memory CD8 T-cell': '57.3', 'Effector memory CD8 T-cell': '67.9', 'Terminal effector memory CD8 T-cell': '62.4', 'Non-switched memory B-cell': '86.6', 'Plasmablast': '62.3', 'Switched memory B-cell': '123.0', 'Exhausted memory B-cell': '102.8', 'Progenitor cell': '81.3', 'Memory T-reg': '64.1', 'Naive CD4 T-cell activated': '65.9', 'Naive CD8 T-cell activated': '65.8', 'Naive T-reg': '79.3'}
2OEV, 2OEW, 2OEX, 2OJQ, 2R02, 2R03, 2R05, 2XS1, 2XS8, 2ZNE, 3C3O, 3C3Q, 3C3R, 3E1R, 3WUV, 4JJY, 5V3R, 5WA1, 6KP3
{'Adipose Tissue': 57.022259136212625, 'Adrenal Gland': 37.84320930232558, 'Bladder': 51.20333333333333, 'Blood': 27.215642626480083, 'Blood Vessel': 68.15737827715357, 'Brain': 23.16814269492809, 'Breast': 56.680174291939, 'Cervix Uteri': 73.45526315789475, 'Colon': 48.26603337612323, 'Esophagus': 56.66821453287198, 'Fallopian Tube': 64.93444444444444, 'Heart': 20.808307781649248, 'Kidney': 25.52556179775281, 'Liver': 15.737867256637168, 'Lung': 64.18974048442907, 'Muscle': 25.633566625155662, 'Nerve': 94.56468497576736, 'Ovary': 69.9893888888889, 'Pancreas': 15.223810975609757, 'Pituitary': 43.96685512367491, 'Prostate': 44.06436734693878, 'Salivary Gland': 45.30228395061729, 'Skin': 64.54143725815368, 'Small Intestine': 54.79823529411765, 'Spleen': 50.25668049792531, 'Stomach': 39.4900278551532, 'Testis': 55.34620498614958, 'Thyroid': 50.38843797856049, 'Uterus': 80.46267605633804, 'Vagina': 70.0626282051282}
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0.01, 0.27, 0.49, 0.47, 0.0, 0.37, 0.65, 0.27, 0.03, 0.69, 0.52, 0.06, 0.38, 0.41, 0.33, 0.3, 0.61, 0.61, 0.28, 0.26, 0.63, 0.57, 0.06, 0.7, 0.44, 0.35, 0.51, 0.76, 0.79, 0.58, 0.9, 0.89, 0.94, 0.93, 0.94, 0.96, 0.88, 0.93, 0.93, 0.97, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.98, 0.98, 0.99, 0.99, 0.94, 0.99, 0.95, 0.85, 0.95, 0.95, 0.91, 0.97, 0.96, 0.92, 0.92, 0.95, 0.9, 0.93, 0.91, 0.92, 0.9, 0.96, 0.93, 0.93, 0.88, 0.91, 0.89, 0.89, 0.89, 0.87, 0.93, 0.98, 0.96, 0.99, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.96, 1.0, 0.93, 1.0, 1.0, 1.0, 0.99, 0.99, 0.98, 0.99, 0.98, 1.0, 1.0, 1.0, 0.98, 1.0, 0.95, 0.96, 0.97, 0.89, 0.97, 0.89, 0.98, 0.9, 0.95, 0.92, 0.95, 0.79, 0.87, 0.77, 0.91, 0.88, 0.65, 0.93, 0.85, 0.72, 0.89, 0.9, 0.86, 0.81, 0.57, 0.84, 0.9, 0.66, 0.53, 0.58, 0.54, 0.39, 0.83, 0.91, 1.0, 1.0, 1.0, 1.0, 0.89, 0.98, 0.88, 0.86, 0.86, 0.8, 0.88, 0.89, 0.93, 0.96, 0.98, 0.96, 0.97, 1.0, 0.95, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 0.92, 0.97, 0.95, 0.96, 0.98, 0.95, 0.99, 0.95, 0.97, 0.96, 0.98, 0.93, 0.99, 1.0, 1.0, 1.0, 1.0]
null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
83.499217
0.429965
699
O60260
Q92783
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
STAM
MPLFATNPFDQDVEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNHQHEGRKVRAIYDFEAAEDNELTFKAGEIITVLDDSDPNWWKGETHQGIGLFPSNFVTADLTAEPEMIKTEKKTVQFSDDVQVETIEPEPEPAFIDEDKMDQLLQMLQSTDPSDDQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSELNVKVMEALSLYTKLMNEDPMYSMYAKLQNQPYYMQSSGVSGSQVYAGPPPSGAYLVAGNAQMSHLQSYSLPPEQLSSLSQAVVPPSANPALPSQQTQAAYPNTMVSSVQGNTYPSQAPVYSPPPAATAAAATADVTLYQNAGPNMPQVPNYNLTSSTLPQPGGSQQPPQPQQPYSQKALL
Homo sapiens
Cytoplasm, Early endosome membrane
Tissue enhanced (bone)
{'Ciliated cells': '13.3', 'Basal respiratory cells': '15.0', 'Club cells': '11.1', 'Ionocytes': '7.7', 'Mucus glandular cells': '11.9', 'Serous glandular cells': '25.2', 'Gastric mucus-secreting cells': '15.3', 'Proximal enterocytes': '5.4', 'Paneth cells': '4.1', 'Distal enterocytes': '5.1', 'Intestinal goblet cells': '8.4', 'Exocrine glandular cells': '-0.671', 'Basal prostatic cells': '13.3', 'Prostatic glandular cells': '25.8', 'Breast glandular cells': '0.346', 'Breast myoepithelial cells': '0.294', 'Glandular and luminal cells': '27.5', 'Secretory cells': '12.9', 'Basal keratinocytes': '25.7', 'Suprabasal keratinocytes': '25.0', 'Basal squamous epithelial cells': '21.3', 'Squamous epithelial cells': '21.2', 'Alveolar cells type 1': '0.173', 'Alveolar cells type 2': '0.504', 'Salivary duct cells': '12.8', 'Ductal cells': '0.531', 'Hepatocytes': '0.359', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.183', 'Distal tubular cells': '9.2', 'Collecting duct cells': '19.4', 'Mesothelial cells': '0.445', 'Sertoli cells': '0.717', 'Granulosa cells': '7.8', 'Enteroendocrine cells': '14.1', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.620', 'Excitatory neurons': '30.6', 'Inhibitory neurons': '35.4', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '13.7', 'Bipolar cells': '16.9', 'Horizontal cells': '12.6', 'Astrocytes': '14.9', 'Oligodendrocyte precursor cells': '29.7', 'Oligodendrocytes': '55.4', 'Microglial cells': '37.6', 'Muller glia cells': '12.8', 'Schwann cells': '0.081', 'Spermatogonia': '0.615', 'Spermatocytes': '0.353', 'Early spermatids': '-0.346', 'Late spermatids': '-0.674', 'Oocytes': '2.2', 'Cytotrophoblasts': '10.4', 'Syncytiotrophoblasts': '36.4', 'Extravillous trophoblasts': '10.9', 'Endothelial cells': '11.9', 'Lymphatic endothelial cells': '13.9', 'Cardiomyocytes': '0.652', 'Skeletal myocytes': '-0.302', 'Smooth muscle cells': '14.7', 'Adipocytes': '12.4', 'Melanocytes': '0.225', 'Fibroblasts': '21.4', 'Peritubular cells': '0.454', 'Endometrial stromal cells': '22.1', 'Ovarian stromal cells': '12.3', 'Undifferentiated cells': '10.4', 'T-cells': '29.8', 'B-cells': '11.9', 'Plasma cells': '15.9', 'Nk-cells': '31.8', 'Granulocytes': '40.5', 'Monocytes': '14.7', 'Macrophages': '15.4', 'Hofbauer cells': '14.8', 'Kupffer cells': '9.8', 'Dendritic cells': '10.7', 'Langerhans cells': '0.269', 'Erythroid cells': '0.037', 'Adipocytes (Subcutaneous)': '-0.062', 'Adipocytes (Visceral)': '-0.311', 'Breast glandular cells (progenitors)': '0.176', 'Adipocytes (Breast)': '-0.256', 'Colon enterocytes': '-0.182', 'Colon enteroendocrine cells': '0.391', 'Enteric glia cells': '0.304', 'Mitotic cells (Colon)': '-0.080', 'Mitotic cells (Heart)': '0.493', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.383', 'Intercalated cells': '-0.025', 'Cholangiocyte': '0.390', 'NK-cells (Liver)': '-0.310', 'Respiratory ciliated cells': '-0.114', 'Mitotic cells (Lung)': '0.105', 'NK-cells (Lung)': '-0.243', 'B-cells (Lung)': '-0.222', 'Alpha cells': '0.327', 'Beta cells': '0.137', 'Prostate glandular cells': '0.188', 'Prostate basal glandular cells': '0.088', 'Urothelial cells': '-0.101', 'Keratinocyte (other)': '0.275', 'Keratinocyte (granular)': '0.024', 'Hair cortex cells': '-0.207', 'Inner root sheath cells': '-0.101', 'Outer root sheath cells': '-0.047', 'Sebaceous gland cells': '-0.071', 'Eccrine sweat gland cells': '-0.117', 'Adipocytes (Skin)': '-0.213', 'Mitotic cells (Skin)': '0.263', 'Parietal cells': '-0.057', 'Chief cells': '0.125', 'Gastric mucous cells': '0.057', 'Gastric enteroendocrine cells': '0.103', 'Mitotic cells (Stomach)': '0.117', 'Parafollicular cells': '0.050', 'Thyroid glandular cells': '0.264', 'Mitotic cells (Thyroid)': '0.130', 'Adrenal cortex cells': '0.683', 'Adrenal medulla cells': '0.068', 'Mitotic cells (Adrenal gland)': '0.470', 'Minor salivary glandular cells': '0.249', 'Minor salivary gland ductal cells': '-0.114', 'Minor salivary gland basal cells': '0.559', 'Mitotic cells (Minor salivary gland)': '0.544', 'Adipocytes (Minor salivary gland)': '0.217', 'Somatotropes': '-0.076', 'Lactotropes': '-0.005', 'Gonadotropes': '0.226', 'Corticotropes': '-0.068', 'Thyrotropes': '0.191', 'Undifferentiated cells (Pituitary gland)': '0.200', 'Mitotic cells (Spleen)': '-0.064', 'Platelets': '-0.026', 'Erythrocytes': '0.029', 'Hematopoietic stem cells': '-0.077', 'B-cells (Spleen)': '0.158', 'NK-cells (Spleen)': '0.234', 'Amygdala excitatory': '51.8', 'Cerebellar inhibitory': '52.6', 'Cge interneuron': '47.2', 'Deep-layer corticothalamic and 6b': '45.3', 'Deep-layer intratelencephalic': '47.5', 'Deep-layer near-projecting': '38.9', 'Eccentric medium spiny neuron': '47.5', 'Hippocampal ca1-3': '46.8', 'Hippocampal ca4': '51.1', 'Hippocampal dentate gyrus': '72.0', 'Lamp5-lhx6 and chandelier': '79.4', 'Lower rhombic lip': '57.7', 'Mammillary body': '58.7', 'Medium spiny neuron': '40.1', 'Mge interneuron': '59.8', 'Midbrain-derived inhibitory': '52.8', 'Miscellaneous': '47.6', 'Splatter': '52.1', 'Thalamic excitatory': '59.1', 'Upper rhombic lip': '85.5', 'Upper-layer intratelencephalic': '45.2', 'Astrocyte': '31.8', 'Bergmann glia': '34.3', 'Central nervous system macrophage': '93.1', 'Choroid plexus epithelial cell': '38.7', 'Committed oligodendrocyte precursor': '52.8', 'Ependymal cell': '29.6', 'Oligodendrocyte': '87.5', 'Oligodendrocyte precursor cell': '56.2', 'Endothelial cell': '49.5', 'Pericyte': '37.0', 'Vascular associated smooth muscle cell': '47.4', 'Fibroblast': '84.5', 'Leukocyte': '61.2', 'Basophil': '66.7', 'Eosinophil': '12.6', 'Neutrophil': '21.7', 'Classical monocyte': '23.3', 'Non-classical monocyte': '35.6', 'Intermediate monocyte': '24.5', 'T-reg': '99.9', 'GdT-cell': '5.9', 'MAIT T-cell': '19.9', 'Memory CD4 T-cell': '12.8', 'Naive CD4 T-cell': '50.0', 'Memory CD8 T-cell': '6.2', 'Naive CD8 T-cell': '41.4', 'Memory B-cell': '5.4', 'Naive B-cell': '41.6', 'Plasmacytoid DC': '26.1', 'Myeloid DC': '23.0', 'NK-cell': '53.4', 'Total PBMC': '24.0', 'Vd2 gdTCR': '16.4', 'Memory CD4 T-cell TFH': '74.5', 'Memory CD4 T-cell Th2': '120.2', 'Memory CD4 T-cell Th17': '116.2', 'Memory CD4 T-cell Th1\\/Th17': '50.1', 'Non-Vd2 gdTCR': '20.7', 'Memory CD4 T-cell Th1': '47.7', 'Terminal effector memory CD4 T-cell': '17.9', 'Central memory CD8 T-cell': '26.1', 'Effector memory CD8 T-cell': '24.0', 'Terminal effector memory CD8 T-cell': '18.7', 'Switched memory B-cell': '8.5', 'Plasmablast': '12.0', 'Non-switched memory B-cell': '17.3', 'Exhausted memory B-cell': '11.9', 'Progenitor cell': '66.6', 'Naive CD4 T-cell activated': '33.4', 'Naive CD8 T-cell activated': '35.1', 'Memory T-reg': '441.5', 'Naive T-reg': '217.4'}
2L0A, 3F1I, 3LDZ
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
67.772056
0.635019
1,444
O60260
Q92844
31558697
UbiNet, UbiBrowser
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
TANK
MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET
Homo sapiens
Cytoplasm
Low tissue specificity
{'Ciliated cells': '48.0', 'Basal respiratory cells': '79.0', 'Club cells': '54.4', 'Ionocytes': '59.3', 'Mucus glandular cells': '39.1', 'Serous glandular cells': '24.7', 'Gastric mucus-secreting cells': '23.0', 'Proximal enterocytes': '30.9', 'Paneth cells': '43.0', 'Distal enterocytes': '39.0', 'Intestinal goblet cells': '29.4', 'Exocrine glandular cells': '-0.672', 'Basal prostatic cells': '43.3', 'Prostatic glandular cells': '27.8', 'Breast glandular cells': '0.585', 'Breast myoepithelial cells': '0.700', 'Glandular and luminal cells': '51.4', 'Secretory cells': '89.1', 'Basal keratinocytes': '45.1', 'Suprabasal keratinocytes': '50.4', 'Basal squamous epithelial cells': '25.7', 'Squamous epithelial cells': '28.2', 'Alveolar cells type 1': '0.173', 'Alveolar cells type 2': '-0.317', 'Salivary duct cells': '44.2', 'Ductal cells': '0.645', 'Hepatocytes': '0.240', 'Cholangiocytes': '42.0', 'Proximal tubular cells': '0.173', 'Distal tubular cells': '46.1', 'Collecting duct cells': '37.0', 'Mesothelial cells': '0.228', 'Sertoli cells': '0.324', 'Granulosa cells': '31.1', 'Enteroendocrine cells': '33.2', 'Pancreatic endocrine cells': '32.3', 'Leydig cells': '0.442', 'Excitatory neurons': '48.2', 'Inhibitory neurons': '58.3', 'Cone photoreceptor cells': '34.0', 'Rod photoreceptor cells': '28.5', 'Bipolar cells': '28.6', 'Horizontal cells': '17.0', 'Astrocytes': '78.0', 'Oligodendrocyte precursor cells': '59.4', 'Oligodendrocytes': '81.3', 'Microglial cells': '115.4', 'Muller glia cells': '34.2', 'Schwann cells': '0.125', 'Spermatogonia': '0.459', 'Spermatocytes': '0.453', 'Early spermatids': '0.024', 'Late spermatids': '-0.500', 'Oocytes': '34.6', 'Cytotrophoblasts': '42.5', 'Syncytiotrophoblasts': '156.2', 'Extravillous trophoblasts': '91.8', 'Endothelial cells': '38.1', 'Lymphatic endothelial cells': '52.3', 'Cardiomyocytes': '0.529', 'Skeletal myocytes': '-0.323', 'Smooth muscle cells': '37.9', 'Adipocytes': '34.2', 'Melanocytes': '-0.045', 'Fibroblasts': '59.1', 'Peritubular cells': '0.405', 'Endometrial stromal cells': '41.7', 'Ovarian stromal cells': '39.3', 'Undifferentiated cells': '30.1', 'T-cells': '91.3', 'B-cells': '105.5', 'Plasma cells': '47.4', 'Nk-cells': '48.0', 'Granulocytes': '97.9', 'Monocytes': '285.3', 'Macrophages': '108.3', 'Hofbauer cells': '53.6', 'Kupffer cells': '65.1', 'Dendritic cells': '39.8', 'Langerhans cells': '0.153', 'Erythroid cells': '0.110', 'Adipocytes (Subcutaneous)': '0.109', 'Adipocytes (Visceral)': '-0.087', 'Breast glandular cells (progenitors)': '0.519', 'Adipocytes (Breast)': '-0.579', 'Colon enterocytes': '-0.122', 'Colon enteroendocrine cells': '0.302', 'Enteric glia cells': '0.043', 'Mitotic cells (Colon)': '0.077', 'Mitotic cells (Heart)': '0.495', 'Podocytes': '-0.034', 'Ascending Loop of Henle cells': '0.352', 'Intercalated cells': '-0.069', 'Cholangiocyte': '0.274', 'NK-cells (Liver)': '-0.144', 'Respiratory ciliated cells': '0.030', 'Mitotic cells (Lung)': '-0.149', 'NK-cells (Lung)': '0.406', 'B-cells (Lung)': '0.201', 'Alpha cells': '0.405', 'Beta cells': '0.217', 'Prostate glandular cells': '-0.509', 'Prostate basal glandular cells': '0.028', 'Urothelial cells': '0.240', 'Keratinocyte (other)': '0.004', 'Keratinocyte (granular)': '-0.246', 'Hair cortex cells': '0.005', 'Inner root sheath cells': '0.090', 'Outer root sheath cells': '0.327', 'Sebaceous gland cells': '0.119', 'Eccrine sweat gland cells': '0.169', 'Adipocytes (Skin)': '-0.015', 'Mitotic cells (Skin)': '0.227', 'Parietal cells': '-0.701', 'Chief cells': '-0.631', 'Gastric mucous cells': '-0.420', 'Gastric enteroendocrine cells': '-0.452', 'Mitotic cells (Stomach)': '-0.008', 'Parafollicular cells': '0.051', 'Thyroid glandular cells': '0.191', 'Mitotic cells (Thyroid)': '0.111', 'Adrenal cortex cells': '0.569', 'Adrenal medulla cells': '0.028', 'Mitotic cells (Adrenal gland)': '0.306', 'Minor salivary glandular cells': '0.705', 'Minor salivary gland ductal cells': '0.222', 'Minor salivary gland basal cells': '0.267', 'Mitotic cells (Minor salivary gland)': '0.342', 'Adipocytes (Minor salivary gland)': '0.236', 'Somatotropes': '-0.171', 'Lactotropes': '-0.365', 'Gonadotropes': '-0.200', 'Corticotropes': '-0.141', 'Thyrotropes': '-0.071', 'Undifferentiated cells (Pituitary gland)': '0.418', 'Mitotic cells (Spleen)': '-0.123', 'Platelets': '-0.004', 'Erythrocytes': '-0.033', 'Hematopoietic stem cells': '-0.075', 'B-cells (Spleen)': '0.329', 'NK-cells (Spleen)': '0.297', 'Amygdala excitatory': '76.4', 'Cerebellar inhibitory': '110.0', 'Cge interneuron': '65.9', 'Deep-layer corticothalamic and 6b': '86.1', 'Deep-layer intratelencephalic': '63.5', 'Deep-layer near-projecting': '93.6', 'Eccentric medium spiny neuron': '153.6', 'Hippocampal ca1-3': '91.5', 'Hippocampal ca4': '35.7', 'Hippocampal dentate gyrus': '46.3', 'Lamp5-lhx6 and chandelier': '75.8', 'Lower rhombic lip': '87.0', 'Mammillary body': '106.9', 'Medium spiny neuron': '130.5', 'Mge interneuron': '97.0', 'Midbrain-derived inhibitory': '83.4', 'Miscellaneous': '91.4', 'Splatter': '110.5', 'Thalamic excitatory': '82.7', 'Upper rhombic lip': '88.8', 'Upper-layer intratelencephalic': '48.4', 'Astrocyte': '169.0', 'Bergmann glia': '103.4', 'Central nervous system macrophage': '258.1', 'Choroid plexus epithelial cell': '127.0', 'Committed oligodendrocyte precursor': '85.7', 'Ependymal cell': '94.6', 'Oligodendrocyte': '133.0', 'Oligodendrocyte precursor cell': '109.2', 'Endothelial cell': '271.4', 'Pericyte': '122.9', 'Vascular associated smooth muscle cell': '101.7', 'Fibroblast': '419.0', 'Leukocyte': '282.0', 'Basophil': '302.9', 'Eosinophil': '97.5', 'Neutrophil': '673.4', 'Classical monocyte': '49.6', 'Non-classical monocyte': '78.6', 'Intermediate monocyte': '293.2', 'T-reg': '166.5', 'GdT-cell': '36.1', 'MAIT T-cell': '172.9', 'Memory CD4 T-cell': '59.0', 'Naive CD4 T-cell': '37.8', 'Memory CD8 T-cell': '53.1', 'Naive CD8 T-cell': '26.7', 'Memory B-cell': '64.0', 'Naive B-cell': '108.2', 'Plasmacytoid DC': '156.8', 'Myeloid DC': '216.8', 'NK-cell': '32.6', 'Total PBMC': '187.0', 'Vd2 gdTCR': '123.3', 'Memory CD4 T-cell Th1\\/Th17': '71.7', 'Memory CD4 T-cell Th17': '58.0', 'Memory CD4 T-cell Th2': '48.3', 'Non-Vd2 gdTCR': '143.5', 'Memory CD4 T-cell Th1': '51.7', 'Memory CD4 T-cell TFH': '46.0', 'Terminal effector memory CD4 T-cell': '138.8', 'Central memory CD8 T-cell': '175.8', 'Effector memory CD8 T-cell': '184.9', 'Terminal effector memory CD8 T-cell': '139.1', 'Non-switched memory B-cell': '224.7', 'Plasmablast': '148.7', 'Switched memory B-cell': '228.2', 'Exhausted memory B-cell': '189.2', 'Progenitor cell': '70.3', 'Memory T-reg': '51.1', 'Naive CD4 T-cell activated': '67.2', 'Naive CD8 T-cell activated': '54.0', 'Naive T-reg': '45.8'}
1KZZ, 1L0A, 5H10
{'Adipose Tissue': 24.90334219269103, 'Adrenal Gland': 14.950581395348838, 'Bladder': 23.382380952380952, 'Blood': 18.28330979547901, 'Blood Vessel': 23.424843445692886, 'Brain': 8.23006056018168, 'Breast': 28.856479302832245, 'Cervix Uteri': 19.431578947368426, 'Colon': 16.567102695763797, 'Esophagus': 16.077761937716264, 'Fallopian Tube': 23.55777777777778, 'Heart': 6.422700696864112, 'Kidney': 8.38120224719101, 'Liver': 9.671495575221238, 'Lung': 28.75728373702422, 'Muscle': 16.07690784557908, 'Nerve': 23.530613893376415, 'Ovary': 19.421611111111112, 'Pancreas': 5.048673780487805, 'Pituitary': 16.7013074204947, 'Prostate': 15.761828571428572, 'Salivary Gland': 16.279512345679013, 'Skin': 23.837815367606417, 'Small Intestine': 18.270818181818186, 'Spleen': 21.923340248962653, 'Stomach': 12.006437325905292, 'Testis': 11.415581717451522, 'Thyroid': 21.969108728943336, 'Uterus': 20.779366197183094, 'Vagina': 20.83201923076923}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
59.589576
0.788071
1,867
O60260
Q969Z3
33082525
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
MTARC2
MGASSSSALARLGLPARPWPRWLGVAALGLAAVALGTVAWRRAWPRRRRRLQQVGTVAKLWIYPVKSCKGVPVSEAECTAMGLRSGNLRDRFWLVIKEDGHMVTARQEPRLVLISIIYENNCLIFRAPDMDQLVLPSKQPSSNKLHNCRIFGLDIKGRDCGNEAAKWFTNFLKTEAYRLVQFETNMKGRTSRKLLPTLDQNFQVAYPDYCPLLIMTDASLVDLNTRMEKKMKMENFRPNIVVTGCDAFEEDTWDELLIGSVEVKKVMACPRCILTTVDPDTGVIDRKQPLDTLKSYRLCDPSERELYKLSPLFGIYYSVEKIGSLRVGDPVYRMV
Homo sapiens
Mitochondrion outer membrane, Peroxisome
Tissue enhanced (kidney, liver)
{'Ciliated cells': '8.7', 'Basal respiratory cells': '1.6', 'Club cells': '5.6', 'Ionocytes': '2.2', 'Mucus glandular cells': '8.5', 'Serous glandular cells': '15.5', 'Gastric mucus-secreting cells': '14.1', 'Proximal enterocytes': '61.9', 'Paneth cells': '16.6', 'Distal enterocytes': '14.3', 'Intestinal goblet cells': '13.6', 'Exocrine glandular cells': '-0.270', 'Basal prostatic cells': '5.8', 'Prostatic glandular cells': '13.6', 'Breast glandular cells': '0.012', 'Breast myoepithelial cells': '-0.070', 'Glandular and luminal cells': '6.2', 'Secretory cells': '4.6', 'Basal keratinocytes': '1.7', 'Suprabasal keratinocytes': '1.7', 'Basal squamous epithelial cells': '2.9', 'Squamous epithelial cells': '4.4', 'Alveolar cells type 1': '0.432', 'Alveolar cells type 2': '-0.052', 'Salivary duct cells': '12.1', 'Ductal cells': '0.395', 'Hepatocytes': '0.555', 'Cholangiocytes': '19.1', 'Proximal tubular cells': '0.481', 'Distal tubular cells': '3.1', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.149', 'Sertoli cells': '0.691', 'Granulosa cells': '26.0', 'Enteroendocrine cells': '4.7', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.622', 'Excitatory neurons': '25.4', 'Inhibitory neurons': '11.1', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '1.3', 'Horizontal cells': '0.0', 'Astrocytes': '34.7', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '1.2', 'Microglial cells': '8.1', 'Muller glia cells': '7.8', 'Schwann cells': '0.135', 'Spermatogonia': '0.368', 'Spermatocytes': '-0.014', 'Early spermatids': '-0.552', 'Late spermatids': '-0.709', 'Oocytes': '12.5', 'Cytotrophoblasts': '0.9', 'Syncytiotrophoblasts': '5.6', 'Extravillous trophoblasts': '0.6', 'Endothelial cells': '14.6', 'Lymphatic endothelial cells': '9.6', 'Cardiomyocytes': '0.661', 'Skeletal myocytes': '0.607', 'Smooth muscle cells': '15.5', 'Adipocytes': '14.8', 'Melanocytes': '-0.167', 'Fibroblasts': '13.0', 'Peritubular cells': '0.629', 'Endometrial stromal cells': '1.2', 'Ovarian stromal cells': '16.7', 'Undifferentiated cells': '15.9', 'T-cells': '0.6', 'B-cells': '8.9', 'Plasma cells': '4.4', 'Nk-cells': '0.1', 'Granulocytes': '5.2', 'Monocytes': '0.0', 'Macrophages': '1.4', 'Hofbauer cells': '0.5', 'Kupffer cells': '11.7', 'Dendritic cells': '0.0', 'Langerhans cells': '-0.064', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '0.099', 'Adipocytes (Visceral)': '0.117', 'Breast glandular cells (progenitors)': '-0.082', 'Adipocytes (Breast)': '0.270', 'Colon enterocytes': '-0.052', 'Colon enteroendocrine cells': '0.363', 'Enteric glia cells': '0.549', 'Mitotic cells (Colon)': '-0.041', 'Mitotic cells (Heart)': '0.355', 'Podocytes': '0.156', 'Ascending Loop of Henle cells': '0.271', 'Intercalated cells': '0.230', 'Cholangiocyte': '-0.186', 'NK-cells (Liver)': '0.257', 'Respiratory ciliated cells': '-0.064', 'Mitotic cells (Lung)': '-0.110', 'NK-cells (Lung)': '0.149', 'B-cells (Lung)': '-0.112', 'Alpha cells': '0.357', 'Beta cells': '0.256', 'Prostate glandular cells': '-0.033', 'Prostate basal glandular cells': '-0.076', 'Urothelial cells': '-0.068', 'Keratinocyte (other)': '-0.517', 'Keratinocyte (granular)': '-0.453', 'Hair cortex cells': '0.340', 'Inner root sheath cells': '0.327', 'Outer root sheath cells': '0.497', 'Sebaceous gland cells': '0.194', 'Eccrine sweat gland cells': '0.782', 'Adipocytes (Skin)': '0.499', 'Mitotic cells (Skin)': '0.115', 'Parietal cells': '0.633', 'Chief cells': '0.671', 'Gastric mucous cells': '0.462', 'Gastric enteroendocrine cells': '0.585', 'Mitotic cells (Stomach)': '0.097', 'Parafollicular cells': '0.070', 'Thyroid glandular cells': '0.277', 'Mitotic cells (Thyroid)': '-0.118', 'Adrenal cortex cells': '0.609', 'Adrenal medulla cells': '0.085', 'Mitotic cells (Adrenal gland)': '0.247', 'Minor salivary glandular cells': '0.282', 'Minor salivary gland ductal cells': '0.635', 'Minor salivary gland basal cells': '-0.173', 'Mitotic cells (Minor salivary gland)': '-0.227', 'Adipocytes (Minor salivary gland)': '0.123', 'Somatotropes': '-0.350', 'Lactotropes': '-0.084', 'Gonadotropes': '0.259', 'Corticotropes': '0.109', 'Thyrotropes': '0.450', 'Undifferentiated cells (Pituitary gland)': '0.488', 'Mitotic cells (Spleen)': '-0.347', 'Platelets': '-0.269', 'Erythrocytes': '-0.081', 'Hematopoietic stem cells': '-0.250', 'B-cells (Spleen)': '0.164', 'NK-cells (Spleen)': '0.177', 'Amygdala excitatory': '34.9', 'Cerebellar inhibitory': '7.4', 'Cge interneuron': '13.5', 'Deep-layer corticothalamic and 6b': '36.9', 'Deep-layer intratelencephalic': '39.1', 'Deep-layer near-projecting': '38.6', 'Eccentric medium spiny neuron': '33.3', 'Hippocampal ca1-3': '28.1', 'Hippocampal ca4': '23.7', 'Hippocampal dentate gyrus': '18.6', 'Lamp5-lhx6 and chandelier': '13.7', 'Lower rhombic lip': '15.6', 'Mammillary body': '4.2', 'Medium spiny neuron': '18.1', 'Mge interneuron': '27.5', 'Midbrain-derived inhibitory': '50.7', 'Miscellaneous': '29.1', 'Splatter': '24.5', 'Thalamic excitatory': '23.0', 'Upper rhombic lip': '7.1', 'Upper-layer intratelencephalic': '40.8', 'Astrocyte': '61.5', 'Bergmann glia': '26.7', 'Central nervous system macrophage': '3.5', 'Choroid plexus epithelial cell': '217.5', 'Committed oligodendrocyte precursor': '9.9', 'Ependymal cell': '57.2', 'Oligodendrocyte': '0.8', 'Oligodendrocyte precursor cell': '14.7', 'Endothelial cell': '40.6', 'Pericyte': '39.3', 'Vascular associated smooth muscle cell': '36.2', 'Fibroblast': '25.1', 'Leukocyte': '1.4', 'Basophil': '5.8', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.7', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.2', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '2.2', 'Naive B-cell': '3.8', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.8', 'Total PBMC': '0.8', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '3.5', 'Plasmablast': '5.7', 'Switched memory B-cell': '13.3', 'Exhausted memory B-cell': '14.3', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
null
{}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
91.078328
0.349254
2,230
O60260
Q96AE4
16672220
UbiNet, UbiBrowser
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
FUBP1
MADYSTVPPPSSGSAGGGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAYYAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ
Homo sapiens
Nucleus
Low tissue specificity
{'Ciliated cells': '51.1', 'Basal respiratory cells': '51.6', 'Club cells': '46.0', 'Ionocytes': '43.1', 'Mucus glandular cells': '51.0', 'Serous glandular cells': '39.2', 'Gastric mucus-secreting cells': '32.4', 'Proximal enterocytes': '22.4', 'Paneth cells': '33.8', 'Distal enterocytes': '32.9', 'Intestinal goblet cells': '40.1', 'Exocrine glandular cells': '-0.660', 'Basal prostatic cells': '68.7', 'Prostatic glandular cells': '51.4', 'Breast glandular cells': '0.587', 'Breast myoepithelial cells': '0.643', 'Glandular and luminal cells': '67.7', 'Secretory cells': '62.9', 'Basal keratinocytes': '74.1', 'Suprabasal keratinocytes': '52.4', 'Basal squamous epithelial cells': '45.9', 'Squamous epithelial cells': '45.8', 'Alveolar cells type 1': '0.108', 'Alveolar cells type 2': '-0.426', 'Salivary duct cells': '49.0', 'Ductal cells': '0.593', 'Hepatocytes': '0.417', 'Cholangiocytes': '30.5', 'Proximal tubular cells': '0.167', 'Distal tubular cells': '36.9', 'Collecting duct cells': '42.8', 'Mesothelial cells': '0.390', 'Sertoli cells': '0.506', 'Granulosa cells': '51.0', 'Enteroendocrine cells': '44.7', 'Pancreatic endocrine cells': '47.5', 'Leydig cells': '0.559', 'Excitatory neurons': '47.2', 'Inhibitory neurons': '51.3', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '50.2', 'Bipolar cells': '47.9', 'Horizontal cells': '32.7', 'Astrocytes': '45.5', 'Oligodendrocyte precursor cells': '52.8', 'Oligodendrocytes': '82.2', 'Microglial cells': '59.0', 'Muller glia cells': '37.3', 'Schwann cells': '0.178', 'Spermatogonia': '0.493', 'Spermatocytes': '0.228', 'Early spermatids': '-0.343', 'Late spermatids': '-0.616', 'Oocytes': '34.6', 'Cytotrophoblasts': '49.5', 'Syncytiotrophoblasts': '32.8', 'Extravillous trophoblasts': '72.1', 'Endothelial cells': '49.0', 'Lymphatic endothelial cells': '48.9', 'Cardiomyocytes': '0.611', 'Skeletal myocytes': '0.010', 'Smooth muscle cells': '42.8', 'Adipocytes': '43.3', 'Melanocytes': '0.041', 'Fibroblasts': '42.5', 'Peritubular cells': '0.627', 'Endometrial stromal cells': '54.8', 'Ovarian stromal cells': '56.8', 'Undifferentiated cells': '44.8', 'T-cells': '80.1', 'B-cells': '75.1', 'Plasma cells': '67.7', 'Nk-cells': '92.5', 'Granulocytes': '65.5', 'Monocytes': '68.9', 'Macrophages': '52.3', 'Hofbauer cells': '36.4', 'Kupffer cells': '30.9', 'Dendritic cells': '60.5', 'Langerhans cells': '0.079', 'Erythroid cells': '-0.006', 'Adipocytes (Subcutaneous)': '-0.466', 'Adipocytes (Visceral)': '-0.426', 'Breast glandular cells (progenitors)': '0.446', 'Adipocytes (Breast)': '-0.618', 'Colon enterocytes': '-0.045', 'Colon enteroendocrine cells': '0.258', 'Enteric glia cells': '0.438', 'Mitotic cells (Colon)': '0.002', 'Mitotic cells (Heart)': '0.483', 'Podocytes': '-0.008', 'Ascending Loop of Henle cells': '0.426', 'Intercalated cells': '0.006', 'Cholangiocyte': '0.406', 'NK-cells (Liver)': '-0.203', 'Respiratory ciliated cells': '0.111', 'Mitotic cells (Lung)': '-0.164', 'NK-cells (Lung)': '0.460', 'B-cells (Lung)': '0.297', 'Alpha cells': '0.396', 'Beta cells': '0.214', 'Prostate glandular cells': '-0.212', 'Prostate basal glandular cells': '0.220', 'Urothelial cells': '0.300', 'Keratinocyte (other)': '0.094', 'Keratinocyte (granular)': '-0.404', 'Hair cortex cells': '-0.009', 'Inner root sheath cells': '0.050', 'Outer root sheath cells': '0.304', 'Sebaceous gland cells': '0.059', 'Eccrine sweat gland cells': '0.161', 'Adipocytes (Skin)': '-0.057', 'Mitotic cells (Skin)': '0.335', 'Parietal cells': '-0.546', 'Chief cells': '-0.422', 'Gastric mucous cells': '-0.225', 'Gastric enteroendocrine cells': '-0.223', 'Mitotic cells (Stomach)': '0.115', 'Parafollicular cells': '0.090', 'Thyroid glandular cells': '0.198', 'Mitotic cells (Thyroid)': '-0.017', 'Adrenal cortex cells': '0.303', 'Adrenal medulla cells': '0.018', 'Mitotic cells (Adrenal gland)': '0.077', 'Minor salivary glandular cells': '0.537', 'Minor salivary gland ductal cells': '0.359', 'Minor salivary gland basal cells': '0.075', 'Mitotic cells (Minor salivary gland)': '0.123', 'Adipocytes (Minor salivary gland)': '0.125', 'Somatotropes': '0.086', 'Lactotropes': '0.097', 'Gonadotropes': '0.128', 'Corticotropes': '-0.172', 'Thyrotropes': '0.178', 'Undifferentiated cells (Pituitary gland)': '0.250', 'Mitotic cells (Spleen)': '0.022', 'Platelets': '-0.227', 'Erythrocytes': '-0.076', 'Hematopoietic stem cells': '-0.248', 'B-cells (Spleen)': '0.328', 'NK-cells (Spleen)': '0.243', 'Amygdala excitatory': '69.6', 'Cerebellar inhibitory': '77.0', 'Cge interneuron': '78.6', 'Deep-layer corticothalamic and 6b': '61.3', 'Deep-layer intratelencephalic': '59.5', 'Deep-layer near-projecting': '69.4', 'Eccentric medium spiny neuron': '84.4', 'Hippocampal ca1-3': '61.8', 'Hippocampal ca4': '61.7', 'Hippocampal dentate gyrus': '79.2', 'Lamp5-lhx6 and chandelier': '70.2', 'Lower rhombic lip': '49.4', 'Mammillary body': '72.5', 'Medium spiny neuron': '72.5', 'Mge interneuron': '69.3', 'Midbrain-derived inhibitory': '87.0', 'Miscellaneous': '62.4', 'Splatter': '65.6', 'Thalamic excitatory': '65.4', 'Upper rhombic lip': '91.9', 'Upper-layer intratelencephalic': '67.9', 'Astrocyte': '95.5', 'Bergmann glia': '80.0', 'Central nervous system macrophage': '158.3', 'Choroid plexus epithelial cell': '112.9', 'Committed oligodendrocyte precursor': '94.9', 'Ependymal cell': '85.9', 'Oligodendrocyte': '116.8', 'Oligodendrocyte precursor cell': '108.3', 'Endothelial cell': '132.7', 'Pericyte': '112.3', 'Vascular associated smooth muscle cell': '115.2', 'Fibroblast': '114.3', 'Leukocyte': '184.5', 'Basophil': '60.8', 'Eosinophil': '13.2', 'Neutrophil': '29.6', 'Classical monocyte': '54.6', 'Non-classical monocyte': '86.3', 'Intermediate monocyte': '72.3', 'T-reg': '95.6', 'GdT-cell': '20.0', 'MAIT T-cell': '112.7', 'Memory CD4 T-cell': '21.0', 'Naive CD4 T-cell': '166.5', 'Memory CD8 T-cell': '22.4', 'Naive CD8 T-cell': '147.8', 'Memory B-cell': '17.0', 'Naive B-cell': '142.2', 'Plasmacytoid DC': '96.1', 'Myeloid DC': '66.9', 'NK-cell': '141.0', 'Total PBMC': '78.4', 'Vd2 gdTCR': '107.1', 'Memory CD4 T-cell Th1\\/Th17': '132.1', 'Memory CD4 T-cell Th17': '116.8', 'Memory CD4 T-cell Th2': '130.6', 'Non-Vd2 gdTCR': '99.4', 'Memory CD4 T-cell Th1': '121.0', 'Memory CD4 T-cell TFH': '143.9', 'Terminal effector memory CD4 T-cell': '77.3', 'Central memory CD8 T-cell': '100.1', 'Effector memory CD8 T-cell': '105.2', 'Terminal effector memory CD8 T-cell': '98.9', 'Non-switched memory B-cell': '84.1', 'Plasmablast': '114.4', 'Switched memory B-cell': '93.6', 'Exhausted memory B-cell': '84.7', 'Progenitor cell': '95.8', 'Memory T-reg': '148.2', 'Naive CD4 T-cell activated': '430.4', 'Naive CD8 T-cell activated': '364.3', 'Naive T-reg': '245.3'}
1J4W, 2KXH, 4LIJ, 6Y24, 6Y2C, 6Y2D, 8P25
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
63.878851
0.636832
994
O60260
Q96CS3
33082525, 23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
FAF2
MAAPEERDLTQEQTEKLLQFQDLTGIESMDQCRHTLEQHNWNIEAAVQDRLNEQEGVPSVFNPPPSRPLQVNTADHRIYSYVVSRPQPRGLLGWGYYLIMLPFRFTYYTILDIFRFALRFIRPDPRSRVTDPVGDIVSFMHSFEEKYGRAHPVFYQGTYSQALNDAKRELRFLLVYLHGDDHQDSDEFCRNTLCAPEVISLINTRMLFWACSTNKPEGYRVSQALRENTYPFLAMIMLKDRRMTVVGRLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHFSQSLTVIHDFLFSLKESPEKFQIEANFPRRVLPCIPSEEWPNPPTLQEAGLSHTEVLFVQDLTDE
Homo sapiens
Cytoplasm, Lipid droplet, Endoplasmic reticulum
Low tissue specificity
{'Ciliated cells': '27.3', 'Basal respiratory cells': '49.0', 'Club cells': '36.3', 'Ionocytes': '38.7', 'Mucus glandular cells': '33.1', 'Serous glandular cells': '27.8', 'Gastric mucus-secreting cells': '19.5', 'Proximal enterocytes': '15.1', 'Paneth cells': '16.2', 'Distal enterocytes': '18.0', 'Intestinal goblet cells': '17.7', 'Exocrine glandular cells': '-0.738', 'Basal prostatic cells': '29.8', 'Prostatic glandular cells': '36.7', 'Breast glandular cells': '0.440', 'Breast myoepithelial cells': '0.405', 'Glandular and luminal cells': '28.7', 'Secretory cells': '41.0', 'Basal keratinocytes': '18.7', 'Suprabasal keratinocytes': '28.7', 'Basal squamous epithelial cells': '15.7', 'Squamous epithelial cells': '15.4', 'Alveolar cells type 1': '0.062', 'Alveolar cells type 2': '0.487', 'Salivary duct cells': '36.6', 'Ductal cells': '0.642', 'Hepatocytes': '0.408', 'Cholangiocytes': '17.2', 'Proximal tubular cells': '0.158', 'Distal tubular cells': '6.1', 'Collecting duct cells': '17.5', 'Mesothelial cells': '0.426', 'Sertoli cells': '0.464', 'Granulosa cells': '20.4', 'Enteroendocrine cells': '20.5', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.396', 'Excitatory neurons': '28.0', 'Inhibitory neurons': '32.8', 'Cone photoreceptor cells': '40.8', 'Rod photoreceptor cells': '29.0', 'Bipolar cells': '42.9', 'Horizontal cells': '36.5', 'Astrocytes': '25.4', 'Oligodendrocyte precursor cells': '29.7', 'Oligodendrocytes': '33.6', 'Microglial cells': '13.4', 'Muller glia cells': '32.0', 'Schwann cells': '0.019', 'Spermatogonia': '0.557', 'Spermatocytes': '0.682', 'Early spermatids': '0.011', 'Late spermatids': '-0.500', 'Oocytes': '33.8', 'Cytotrophoblasts': '35.6', 'Syncytiotrophoblasts': '61.2', 'Extravillous trophoblasts': '45.0', 'Endothelial cells': '28.0', 'Lymphatic endothelial cells': '35.5', 'Cardiomyocytes': '0.507', 'Skeletal myocytes': '-0.247', 'Smooth muscle cells': '25.0', 'Adipocytes': '25.5', 'Melanocytes': '0.181', 'Fibroblasts': '33.2', 'Peritubular cells': '0.251', 'Endometrial stromal cells': '40.5', 'Ovarian stromal cells': '27.0', 'Undifferentiated cells': '18.7', 'T-cells': '21.0', 'B-cells': '19.1', 'Plasma cells': '31.0', 'Nk-cells': '20.3', 'Granulocytes': '18.6', 'Monocytes': '20.4', 'Macrophages': '19.5', 'Hofbauer cells': '21.7', 'Kupffer cells': '16.6', 'Dendritic cells': '10.3', 'Langerhans cells': '0.200', 'Erythroid cells': '-0.136', 'Adipocytes (Subcutaneous)': '-0.093', 'Adipocytes (Visceral)': '-0.155', 'Breast glandular cells (progenitors)': '0.385', 'Adipocytes (Breast)': '-0.275', 'Colon enterocytes': '-0.123', 'Colon enteroendocrine cells': '0.324', 'Enteric glia cells': '-0.013', 'Mitotic cells (Colon)': '-0.043', 'Mitotic cells (Heart)': '0.519', 'Podocytes': '-0.225', 'Ascending Loop of Henle cells': '0.423', 'Intercalated cells': '-0.160', 'Cholangiocyte': '0.249', 'NK-cells (Liver)': '-0.360', 'Respiratory ciliated cells': '-0.073', 'Mitotic cells (Lung)': '0.182', 'NK-cells (Lung)': '-0.269', 'B-cells (Lung)': '-0.280', 'Alpha cells': '0.406', 'Beta cells': '0.224', 'Prostate glandular cells': '0.230', 'Prostate basal glandular cells': '0.387', 'Urothelial cells': '0.164', 'Keratinocyte (other)': '0.175', 'Keratinocyte (granular)': '0.356', 'Hair cortex cells': '-0.109', 'Inner root sheath cells': '-0.050', 'Outer root sheath cells': '-0.109', 'Sebaceous gland cells': '0.165', 'Eccrine sweat gland cells': '-0.175', 'Adipocytes (Skin)': '-0.030', 'Mitotic cells (Skin)': '0.102', 'Parietal cells': '-0.552', 'Chief cells': '-0.461', 'Gastric mucous cells': '-0.262', 'Gastric enteroendocrine cells': '-0.332', 'Mitotic cells (Stomach)': '0.153', 'Parafollicular cells': '0.047', 'Thyroid glandular cells': '0.428', 'Mitotic cells (Thyroid)': '-0.093', 'Adrenal cortex cells': '0.440', 'Adrenal medulla cells': '0.010', 'Mitotic cells (Adrenal gland)': '0.261', 'Minor salivary glandular cells': '0.525', 'Minor salivary gland ductal cells': '0.072', 'Minor salivary gland basal cells': '0.499', 'Mitotic cells (Minor salivary gland)': '0.479', 'Adipocytes (Minor salivary gland)': '0.107', 'Somatotropes': '-0.078', 'Lactotropes': '-0.176', 'Gonadotropes': '-0.051', 'Corticotropes': '-0.109', 'Thyrotropes': '-0.041', 'Undifferentiated cells (Pituitary gland)': '0.226', 'Mitotic cells (Spleen)': '-0.109', 'Platelets': '-0.096', 'Erythrocytes': '-0.095', 'Hematopoietic stem cells': '-0.283', 'B-cells (Spleen)': '0.289', 'NK-cells (Spleen)': '0.277', 'Amygdala excitatory': '49.8', 'Cerebellar inhibitory': '47.5', 'Cge interneuron': '51.2', 'Deep-layer corticothalamic and 6b': '43.6', 'Deep-layer intratelencephalic': '50.0', 'Deep-layer near-projecting': '47.2', 'Eccentric medium spiny neuron': '49.4', 'Hippocampal ca1-3': '48.0', 'Hippocampal ca4': '47.4', 'Hippocampal dentate gyrus': '50.0', 'Lamp5-lhx6 and chandelier': '50.5', 'Lower rhombic lip': '47.3', 'Mammillary body': '59.5', 'Medium spiny neuron': '46.0', 'Mge interneuron': '54.8', 'Midbrain-derived inhibitory': '48.1', 'Miscellaneous': '42.9', 'Splatter': '47.9', 'Thalamic excitatory': '47.1', 'Upper rhombic lip': '52.6', 'Upper-layer intratelencephalic': '47.9', 'Astrocyte': '60.4', 'Bergmann glia': '45.7', 'Central nervous system macrophage': '70.2', 'Choroid plexus epithelial cell': '85.2', 'Committed oligodendrocyte precursor': '54.5', 'Ependymal cell': '48.9', 'Oligodendrocyte': '58.3', 'Oligodendrocyte precursor cell': '53.5', 'Endothelial cell': '59.3', 'Pericyte': '57.3', 'Vascular associated smooth muscle cell': '50.2', 'Fibroblast': '63.8', 'Leukocyte': '55.5', 'Basophil': '23.9', 'Eosinophil': '4.7', 'Neutrophil': '27.4', 'Classical monocyte': '34.6', 'Non-classical monocyte': '34.1', 'Intermediate monocyte': '28.1', 'T-reg': '32.5', 'GdT-cell': '6.9', 'MAIT T-cell': '20.8', 'Memory CD4 T-cell': '5.6', 'Naive CD4 T-cell': '59.5', 'Memory CD8 T-cell': '7.2', 'Naive CD8 T-cell': '51.7', 'Memory B-cell': '4.9', 'Naive B-cell': '54.2', 'Plasmacytoid DC': '26.7', 'Myeloid DC': '33.4', 'NK-cell': '54.1', 'Total PBMC': '27.4', 'Vd2 gdTCR': '26.5', 'Memory CD4 T-cell Th1\\/Th17': '47.0', 'Memory CD4 T-cell Th17': '47.2', 'Memory CD4 T-cell Th2': '52.0', 'Non-Vd2 gdTCR': '27.4', 'Memory CD4 T-cell Th1': '49.9', 'Memory CD4 T-cell TFH': '45.0', 'Terminal effector memory CD4 T-cell': '27.8', 'Central memory CD8 T-cell': '26.8', 'Effector memory CD8 T-cell': '30.4', 'Terminal effector memory CD8 T-cell': '30.6', 'Non-switched memory B-cell': '20.0', 'Plasmablast': '49.6', 'Switched memory B-cell': '23.2', 'Exhausted memory B-cell': '23.2', 'Progenitor cell': '33.5', 'Memory T-reg': '52.8', 'Naive CD4 T-cell activated': '41.1', 'Naive CD8 T-cell activated': '45.1', 'Naive T-reg': '56.5'}
2DAM
{'Adipose Tissue': 22.94517026578073, 'Adrenal Gland': 24.85649224806202, 'Bladder': 25.608571428571427, 'Blood': 11.826586329386435, 'Blood Vessel': 21.306080149812733, 'Brain': 14.20882740348221, 'Breast': 23.703986928104573, 'Cervix Uteri': 28.085789473684212, 'Colon': 20.73256097560976, 'Esophagus': 21.268087197231832, 'Fallopian Tube': 29.36888888888889, 'Heart': 7.40360162601626, 'Kidney': 9.611674157303373, 'Liver': 12.17983628318584, 'Lung': 23.380093425605537, 'Muscle': 8.419917808219179, 'Nerve': 28.871147011308565, 'Ovary': 29.839, 'Pancreas': 9.844371951219513, 'Pituitary': 25.381060070671374, 'Prostate': 24.727102040816327, 'Salivary Gland': 20.23301234567901, 'Skin': 36.46660033167496, 'Small Intestine': 20.67385026737968, 'Spleen': 22.175759336099585, 'Stomach': 17.019768802228413, 'Testis': 33.356925207756234, 'Thyroid': 28.758094946401226, 'Uterus': 29.53471830985916, 'Vagina': 23.71551282051282}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
85.126
0.40364
1,787
O60260
Q96DX7
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
TRIM44
MASGVGAAFEELPHDGTCDECEPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGAHQGHQLSTLDEAFEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKMFIQQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEGPSGASEEEDT
Homo sapiens
null
Low tissue specificity
{'Ciliated cells': '68.3', 'Basal respiratory cells': '35.5', 'Club cells': '54.9', 'Ionocytes': '38.7', 'Mucus glandular cells': '87.0', 'Serous glandular cells': '53.5', 'Gastric mucus-secreting cells': '73.7', 'Proximal enterocytes': '47.0', 'Paneth cells': '34.6', 'Distal enterocytes': '49.0', 'Intestinal goblet cells': '42.9', 'Exocrine glandular cells': '-0.641', 'Basal prostatic cells': '62.6', 'Prostatic glandular cells': '53.1', 'Breast glandular cells': '0.374', 'Breast myoepithelial cells': '0.314', 'Glandular and luminal cells': '53.5', 'Secretory cells': '64.5', 'Basal keratinocytes': '43.4', 'Suprabasal keratinocytes': '36.5', 'Basal squamous epithelial cells': '58.5', 'Squamous epithelial cells': '44.2', 'Alveolar cells type 1': '0.271', 'Alveolar cells type 2': '-0.023', 'Salivary duct cells': '82.5', 'Ductal cells': '0.632', 'Hepatocytes': '0.515', 'Cholangiocytes': '57.2', 'Proximal tubular cells': '0.383', 'Distal tubular cells': '36.9', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.268', 'Sertoli cells': '0.563', 'Granulosa cells': '47.0', 'Enteroendocrine cells': '41.2', 'Pancreatic endocrine cells': '39.1', 'Leydig cells': '0.592', 'Excitatory neurons': '146.7', 'Inhibitory neurons': '128.9', 'Cone photoreceptor cells': '130.8', 'Rod photoreceptor cells': '173.5', 'Bipolar cells': '189.4', 'Horizontal cells': '175.0', 'Astrocytes': '74.3', 'Oligodendrocyte precursor cells': '114.1', 'Oligodendrocytes': '159.1', 'Microglial cells': '80.5', 'Muller glia cells': '67.6', 'Schwann cells': '0.158', 'Spermatogonia': '0.615', 'Spermatocytes': '0.464', 'Early spermatids': '-0.341', 'Late spermatids': '-0.655', 'Oocytes': '25.7', 'Cytotrophoblasts': '57.2', 'Syncytiotrophoblasts': '50.3', 'Extravillous trophoblasts': '25.6', 'Endothelial cells': '69.3', 'Lymphatic endothelial cells': '60.2', 'Cardiomyocytes': '0.582', 'Skeletal myocytes': '-0.297', 'Smooth muscle cells': '58.2', 'Adipocytes': '65.5', 'Melanocytes': '0.010', 'Fibroblasts': '51.8', 'Peritubular cells': '0.535', 'Endometrial stromal cells': '73.5', 'Ovarian stromal cells': '44.9', 'Undifferentiated cells': '43.7', 'T-cells': '53.0', 'B-cells': '72.7', 'Plasma cells': '54.5', 'Nk-cells': '62.8', 'Granulocytes': '79.8', 'Monocytes': '92.6', 'Macrophages': '79.8', 'Hofbauer cells': '49.3', 'Kupffer cells': '58.7', 'Dendritic cells': '108.7', 'Langerhans cells': '0.101', 'Erythroid cells': '-0.012', 'Adipocytes (Subcutaneous)': '0.082', 'Adipocytes (Visceral)': '-0.219', 'Breast glandular cells (progenitors)': '0.201', 'Adipocytes (Breast)': '-0.261', 'Colon enterocytes': '-0.169', 'Colon enteroendocrine cells': '0.191', 'Enteric glia cells': '-0.080', 'Mitotic cells (Colon)': '-0.080', 'Mitotic cells (Heart)': '0.519', 'Podocytes': '0.025', 'Ascending Loop of Henle cells': '0.321', 'Intercalated cells': '0.077', 'Cholangiocyte': '0.345', 'NK-cells (Liver)': '-0.284', 'Respiratory ciliated cells': '0.015', 'Mitotic cells (Lung)': '-0.078', 'NK-cells (Lung)': '0.108', 'B-cells (Lung)': '-0.103', 'Alpha cells': '0.405', 'Beta cells': '0.225', 'Prostate glandular cells': '-0.266', 'Prostate basal glandular cells': '0.051', 'Urothelial cells': '0.073', 'Keratinocyte (other)': '-0.096', 'Keratinocyte (granular)': '-0.147', 'Hair cortex cells': '-0.028', 'Inner root sheath cells': '0.015', 'Outer root sheath cells': '0.077', 'Sebaceous gland cells': '0.151', 'Eccrine sweat gland cells': '0.134', 'Adipocytes (Skin)': '0.129', 'Mitotic cells (Skin)': '0.106', 'Parietal cells': '-0.602', 'Chief cells': '-0.481', 'Gastric mucous cells': '-0.415', 'Gastric enteroendocrine cells': '-0.386', 'Mitotic cells (Stomach)': '-0.011', 'Parafollicular cells': '0.115', 'Thyroid glandular cells': '0.378', 'Mitotic cells (Thyroid)': '0.057', 'Adrenal cortex cells': '0.598', 'Adrenal medulla cells': '0.066', 'Mitotic cells (Adrenal gland)': '0.350', 'Minor salivary glandular cells': '0.695', 'Minor salivary gland ductal cells': '0.293', 'Minor salivary gland basal cells': '0.210', 'Mitotic cells (Minor salivary gland)': '0.267', 'Adipocytes (Minor salivary gland)': '0.192', 'Somatotropes': '0.008', 'Lactotropes': '-0.044', 'Gonadotropes': '-0.100', 'Corticotropes': '-0.207', 'Thyrotropes': '0.086', 'Undifferentiated cells (Pituitary gland)': '0.207', 'Mitotic cells (Spleen)': '-0.227', 'Platelets': '-0.198', 'Erythrocytes': '-0.138', 'Hematopoietic stem cells': '-0.328', 'B-cells (Spleen)': '0.390', 'NK-cells (Spleen)': '0.329', 'Amygdala excitatory': '200.7', 'Cerebellar inhibitory': '183.0', 'Cge interneuron': '180.5', 'Deep-layer corticothalamic and 6b': '190.3', 'Deep-layer intratelencephalic': '194.7', 'Deep-layer near-projecting': '194.3', 'Eccentric medium spiny neuron': '207.4', 'Hippocampal ca1-3': '202.3', 'Hippocampal ca4': '161.6', 'Hippocampal dentate gyrus': '267.2', 'Lamp5-lhx6 and chandelier': '210.6', 'Lower rhombic lip': '130.5', 'Mammillary body': '229.3', 'Medium spiny neuron': '192.6', 'Mge interneuron': '197.4', 'Midbrain-derived inhibitory': '213.0', 'Miscellaneous': '205.1', 'Splatter': '170.6', 'Thalamic excitatory': '180.6', 'Upper rhombic lip': '255.4', 'Upper-layer intratelencephalic': '200.8', 'Astrocyte': '199.9', 'Bergmann glia': '206.9', 'Central nervous system macrophage': '291.7', 'Choroid plexus epithelial cell': '148.5', 'Committed oligodendrocyte precursor': '154.4', 'Ependymal cell': '162.9', 'Oligodendrocyte': '286.7', 'Oligodendrocyte precursor cell': '220.4', 'Endothelial cell': '168.6', 'Pericyte': '184.3', 'Vascular associated smooth muscle cell': '154.2', 'Fibroblast': '150.9', 'Leukocyte': '166.7', 'Basophil': '6.4', 'Eosinophil': '0.3', 'Neutrophil': '0.6', 'Classical monocyte': '67.1', 'Non-classical monocyte': '96.9', 'Intermediate monocyte': '15.1', 'T-reg': '8.5', 'GdT-cell': '0.9', 'MAIT T-cell': '9.6', 'Memory CD4 T-cell': '0.9', 'Naive CD4 T-cell': '114.7', 'Memory CD8 T-cell': '0.9', 'Naive CD8 T-cell': '95.6', 'Memory B-cell': '1.1', 'Naive B-cell': '123.9', 'Plasmacytoid DC': '20.3', 'Myeloid DC': '18.1', 'NK-cell': '85.8', 'Total PBMC': '11.2', 'Vd2 gdTCR': '10.1', 'Memory CD4 T-cell Th1\\/Th17': '76.7', 'Memory CD4 T-cell Th17': '65.6', 'Memory CD4 T-cell Th2': '73.0', 'Non-Vd2 gdTCR': '10.1', 'Memory CD4 T-cell Th1': '69.6', 'Memory CD4 T-cell TFH': '74.4', 'Terminal effector memory CD4 T-cell': '7.6', 'Central memory CD8 T-cell': '8.6', 'Effector memory CD8 T-cell': '7.2', 'Terminal effector memory CD8 T-cell': '8.6', 'Non-switched memory B-cell': '11.0', 'Plasmablast': '6.7', 'Switched memory B-cell': '12.5', 'Exhausted memory B-cell': '11.7', 'Progenitor cell': '11.2', 'Memory T-reg': '34.4', 'Naive CD4 T-cell activated': '89.1', 'Naive CD8 T-cell activated': '85.1', 'Naive T-reg': '90.4'}
null
{'Adipose Tissue': 22.6436353820598, 'Adrenal Gland': 15.11451550387597, 'Bladder': 24.669047619047618, 'Blood': 9.997348546824542, 'Blood Vessel': 23.785150561797753, 'Brain': 24.67376684330053, 'Breast': 22.588568627450982, 'Cervix Uteri': 24.517894736842106, 'Colon': 22.977911424903724, 'Esophagus': 19.978948788927333, 'Fallopian Tube': 25.028888888888886, 'Heart': 8.354485365853659, 'Kidney': 15.61, 'Liver': 8.570938053097345, 'Lung': 25.682837370242215, 'Muscle': 10.56241594022416, 'Nerve': 30.777318255250403, 'Ovary': 24.009888888888888, 'Pancreas': 11.133359756097562, 'Pituitary': 17.59634275618375, 'Prostate': 20.32123673469388, 'Salivary Gland': 16.541802469135803, 'Skin': 21.272386401326703, 'Small Intestine': 21.671096256684493, 'Spleen': 19.67209543568465, 'Stomach': 16.806114206128136, 'Testis': 14.300213296398892, 'Thyroid': 24.34198468606432, 'Uterus': 28.35295774647887, 'Vagina': 20.44380128205128}
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[52.16, 43.66, 46.06, 52.23, 49.76, 39.47, 43.67, 43.05, 44.43, 44.53, 46.39, 53.1, 57.64, 63.35, 71.6, 76.94, 84.52, 86.89, 83.87, 82.4, 83.95, 77.16, 67.77, 68.42, 67.63, 66.27, 73.49, 78.45, 81.73, 83.87, 88.67, 90.82, 91.29, 87.52, 88.46, 88.58, 84.97, 88.04, 88.98, 89.96, 91.04, 88.36, 88.58, 91.78, 89.61, 90.45, 91.23, 92.39, 90.71, 90.74, 90.95, 88.25, 87.6, 89.35, 90.71, 88.62, 89.6, 87.8, 86.75, 81.28, 75.92, 69.18, 49.83, 44.23, 35.33, 30.67, 31.29, 36.81, 44.07, 47.28, 37.86, 40.7, 39.63, 41.31, 39.18, 40.12, 39.27, 41.37, 40.48, 37.71, 38.03, 36.74, 40.57, 40.18, 42.07, 41.31, 43.3, 42.33, 47.54, 44.84, 52.52, 43.47, 44.48, 46.66, 44.31, 40.23, 44.49, 45.62, 44.52, 44.77, 39.62, 48.42, 43.19, 48.4, 44.69, 51.95, 42.59, 52.41, 42.48, 49.1, 45.38, 42.2, 40.46, 44.25, 47.53, 45.84, 44.81, 48.15, 48.16, 53.97, 44.2, 51.48, 49.97, 48.99, 50.85, 46.34, 54.68, 46.24, 54.74, 45.58, 58.94, 46.99, 58.07, 53.77, 44.32, 49.7, 49.37, 45.48, 55.03, 43.58, 56.76, 47.03, 56.02, 47.63, 42.99, 45.59, 44.45, 43.21, 43.51, 42.81, 56.4, 46.14, 55.56, 50.6, 45.07, 51.85, 46.76, 53.18, 56.04, 53.04, 60.04, 65.81, 62.13, 74.55, 74.33, 74.43, 73.09, 70.24, 69.67, 69.91, 65.45, 69.95, 68.49, 64.25, 63.28, 71.03, 80.68, 90.52, 92.79, 91.8, 92.56, 93.68, 92.17, 92.42, 92.5, 94.41, 93.36, 95.09, 96.5, 96.51, 94.19, 94.51, 94.5, 92.9, 94.46, 95.21, 95.54, 95.22, 94.24, 96.11, 96.28, 94.82, 94.89, 93.41, 89.58, 92.66, 95.6, 95.18, 94.1, 97.41, 96.39, 96.61, 95.77, 95.95, 96.08, 95.96, 96.13, 95.22, 94.82, 94.04, 91.99, 90.29, 88.56, 83.44, 75.04, 64.91, 62.26, 75.45, 85.87, 90.91, 92.46, 93.25, 94.27, 95.21, 95.62, 95.6, 96.65, 96.64, 96.58, 95.79, 95.55, 95.42, 94.49, 94.51, 91.71, 93.79, 94.18, 92.29, 94.29, 93.15, 95.0, 94.11, 96.37, 95.86, 95.42, 96.24, 96.53, 96.95, 96.38, 97.39, 97.22, 96.86, 97.31, 97.37, 95.74, 96.21, 96.93, 96.15, 94.63, 95.05, 95.29, 92.37, 92.51, 93.34, 92.62, 91.73, 92.12, 93.43, 92.74, 94.04, 93.99, 93.42, 94.36, 94.89, 92.63, 93.5, 94.4, 93.56, 91.25, 90.75, 93.83, 93.54, 91.4, 94.0, 96.9, 95.69, 95.72, 97.88, 98.27, 97.61, 98.08, 97.95, 98.12, 97.91, 97.61, 98.1, 97.76, 97.47, 97.5, 97.41, 96.94, 96.61, 95.8, 95.98, 94.5, 94.13, 93.02, 91.73, 89.53, 87.97, 82.22, 76.48, 72.6, 66.93, 57.21, 56.81, 53.32, 54.6, 50.87, 50.71, 53.27, 53.89, 56.66, 53.97, 51.11, 55.58, 51.35, 52.5, 53.83, 50.47, 59.95, 60.63, 63.49, 54.94]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
73.293401
0.642238
2,204
O60260
Q96LZ7
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
RMDN2
MPYSTNKELILGIMVGTAGISLLLLWYHKVRKPGIAMKLPEFLSLGNTFNSITLQDEIHDDQGTTVIFQERQLQILEKLNELLTNMEELKEEIRFLKEAIPKLEEYIQDELGGKITVHKISPQHRARKRRLPTIQSSATSNSSEEAESEGGYITANTDTEEQSFPVPKAFNTRVEELNLDVLLQKVDHLRMSESGKSESFELLRDHKEKFRDEIEFMWRFARAYGDMYELSTNTQEKKHYANIGKTLSERAINRAPMNGHCHLWYAVLCGYVSEFEGLQNKINYGHLFKEHLDIAIKLLPEEPFLYYLKGRYCYTVSKLSWIEKKMAATLFGKIPSSTVQEALHNFLKAEELCPGYSNPNYMYLAKCYTDLEENQNALKFCNLALLLPTVTKEDKEAQKEMQKIMTSLKR
Homo sapiens
Membrane, Cytoplasm, Cytoplasm, cytoskeleton, spindle, Cytoplasm, cytoskeleton, spindle pole
Tissue enhanced (adrenal)
{'Ciliated cells': '5.1', 'Basal respiratory cells': '14.9', 'Club cells': '9.1', 'Ionocytes': '7.4', 'Mucus glandular cells': '4.6', 'Serous glandular cells': '2.3', 'Gastric mucus-secreting cells': '2.4', 'Proximal enterocytes': '29.3', 'Paneth cells': '5.7', 'Distal enterocytes': '29.4', 'Intestinal goblet cells': '14.3', 'Exocrine glandular cells': '-0.276', 'Basal prostatic cells': '4.7', 'Prostatic glandular cells': '2.5', 'Breast glandular cells': '0.356', 'Breast myoepithelial cells': '0.201', 'Glandular and luminal cells': '3.3', 'Secretory cells': '6.0', 'Basal keratinocytes': '2.7', 'Suprabasal keratinocytes': '2.1', 'Basal squamous epithelial cells': '4.0', 'Squamous epithelial cells': '1.6', 'Alveolar cells type 1': '0.120', 'Alveolar cells type 2': '0.436', 'Salivary duct cells': '3.9', 'Ductal cells': '0.340', 'Hepatocytes': '0.622', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.166', 'Distal tubular cells': '6.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.283', 'Sertoli cells': '-0.443', 'Granulosa cells': '3.7', 'Enteroendocrine cells': '14.3', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.444', 'Excitatory neurons': '32.6', 'Inhibitory neurons': '23.5', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '2.0', 'Bipolar cells': '4.4', 'Horizontal cells': '4.4', 'Astrocytes': '23.8', 'Oligodendrocyte precursor cells': '36.8', 'Oligodendrocytes': '6.6', 'Microglial cells': '18.8', 'Muller glia cells': '4.2', 'Schwann cells': '0.147', 'Spermatogonia': '-0.291', 'Spermatocytes': '0.016', 'Early spermatids': '0.758', 'Late spermatids': '0.579', 'Oocytes': '8.1', 'Cytotrophoblasts': '2.1', 'Syncytiotrophoblasts': '0.9', 'Extravillous trophoblasts': '0.9', 'Endothelial cells': '4.2', 'Lymphatic endothelial cells': '2.3', 'Cardiomyocytes': '0.665', 'Skeletal myocytes': '-0.126', 'Smooth muscle cells': '6.5', 'Adipocytes': '3.2', 'Melanocytes': '0.065', 'Fibroblasts': '9.6', 'Peritubular cells': '-0.246', 'Endometrial stromal cells': '12.0', 'Ovarian stromal cells': '4.8', 'Undifferentiated cells': '13.9', 'T-cells': '2.6', 'B-cells': '5.3', 'Plasma cells': '2.5', 'Nk-cells': '6.3', 'Granulocytes': '7.1', 'Monocytes': '3.5', 'Macrophages': '5.0', 'Hofbauer cells': '5.0', 'Kupffer cells': '5.6', 'Dendritic cells': '4.0', 'Langerhans cells': '0.219', 'Erythroid cells': '-0.060', 'Adipocytes (Subcutaneous)': '0.089', 'Adipocytes (Visceral)': '-0.040', 'Breast glandular cells (progenitors)': '0.216', 'Adipocytes (Breast)': '-0.113', 'Colon enterocytes': '0.237', 'Colon enteroendocrine cells': '-0.015', 'Enteric glia cells': '-0.288', 'Mitotic cells (Colon)': '0.228', 'Mitotic cells (Heart)': '0.439', 'Podocytes': '-0.141', 'Ascending Loop of Henle cells': '0.575', 'Intercalated cells': '0.061', 'Cholangiocyte': '0.007', 'NK-cells (Liver)': '0.007', 'Respiratory ciliated cells': '-0.049', 'Mitotic cells (Lung)': '0.143', 'NK-cells (Lung)': '-0.290', 'B-cells (Lung)': '-0.287', 'Alpha cells': '0.374', 'Beta cells': '0.263', 'Prostate glandular cells': '-0.176', 'Prostate basal glandular cells': '0.195', 'Urothelial cells': '0.087', 'Keratinocyte (other)': '-0.207', 'Keratinocyte (granular)': '-0.267', 'Hair cortex cells': '0.153', 'Inner root sheath cells': '0.245', 'Outer root sheath cells': '0.383', 'Sebaceous gland cells': '0.271', 'Eccrine sweat gland cells': '0.270', 'Adipocytes (Skin)': '0.236', 'Mitotic cells (Skin)': '0.250', 'Parietal cells': '-0.648', 'Chief cells': '-0.583', 'Gastric mucous cells': '-0.511', 'Gastric enteroendocrine cells': '-0.433', 'Mitotic cells (Stomach)': '-0.035', 'Parafollicular cells': '0.083', 'Thyroid glandular cells': '0.417', 'Mitotic cells (Thyroid)': '0.131', 'Adrenal cortex cells': '0.628', 'Adrenal medulla cells': '0.047', 'Mitotic cells (Adrenal gland)': '0.342', 'Minor salivary glandular cells': '0.517', 'Minor salivary gland ductal cells': '0.369', 'Minor salivary gland basal cells': '0.037', 'Mitotic cells (Minor salivary gland)': '0.170', 'Adipocytes (Minor salivary gland)': '0.262', 'Somatotropes': '-0.131', 'Lactotropes': '-0.277', 'Gonadotropes': '0.045', 'Corticotropes': '-0.141', 'Thyrotropes': '0.044', 'Undifferentiated cells (Pituitary gland)': '0.451', 'Mitotic cells (Spleen)': '-0.252', 'Platelets': '-0.085', 'Erythrocytes': '-0.105', 'Hematopoietic stem cells': '-0.197', 'B-cells (Spleen)': '0.135', 'NK-cells (Spleen)': '0.385', 'Amygdala excitatory': '50.9', 'Cerebellar inhibitory': '56.0', 'Cge interneuron': '33.6', 'Deep-layer corticothalamic and 6b': '39.2', 'Deep-layer intratelencephalic': '35.8', 'Deep-layer near-projecting': '71.7', 'Eccentric medium spiny neuron': '51.5', 'Hippocampal ca1-3': '56.9', 'Hippocampal ca4': '37.0', 'Hippocampal dentate gyrus': '85.7', 'Lamp5-lhx6 and chandelier': '43.0', 'Lower rhombic lip': '26.7', 'Mammillary body': '30.0', 'Medium spiny neuron': '53.6', 'Mge interneuron': '38.5', 'Midbrain-derived inhibitory': '47.5', 'Miscellaneous': '36.7', 'Splatter': '36.1', 'Thalamic excitatory': '33.7', 'Upper rhombic lip': '35.7', 'Upper-layer intratelencephalic': '48.5', 'Astrocyte': '55.3', 'Bergmann glia': '46.1', 'Central nervous system macrophage': '43.2', 'Choroid plexus epithelial cell': '35.5', 'Committed oligodendrocyte precursor': '23.1', 'Ependymal cell': '30.7', 'Oligodendrocyte': '15.2', 'Oligodendrocyte precursor cell': '48.2', 'Endothelial cell': '23.3', 'Pericyte': '46.7', 'Vascular associated smooth muscle cell': '38.4', 'Fibroblast': '60.1', 'Leukocyte': '19.1', 'Basophil': '3.5', 'Eosinophil': '0.7', 'Neutrophil': '27.3', 'Classical monocyte': '5.0', 'Non-classical monocyte': '8.4', 'Intermediate monocyte': '30.4', 'T-reg': '2.7', 'GdT-cell': '2.0', 'MAIT T-cell': '17.6', 'Memory CD4 T-cell': '1.0', 'Naive CD4 T-cell': '3.7', 'Memory CD8 T-cell': '1.3', 'Naive CD8 T-cell': '4.6', 'Memory B-cell': '4.1', 'Naive B-cell': '10.5', 'Plasmacytoid DC': '24.4', 'Myeloid DC': '10.7', 'NK-cell': '6.4', 'Total PBMC': '16.0', 'Vd2 gdTCR': '10.2', 'Memory CD4 T-cell Th1\\/Th17': '2.6', 'Memory CD4 T-cell Th17': '1.7', 'Memory CD4 T-cell Th2': '1.2', 'Non-Vd2 gdTCR': '12.4', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '1.4', 'Terminal effector memory CD4 T-cell': '8.2', 'Central memory CD8 T-cell': '7.5', 'Effector memory CD8 T-cell': '9.9', 'Terminal effector memory CD8 T-cell': '12.3', 'Non-switched memory B-cell': '33.5', 'Plasmablast': '8.6', 'Switched memory B-cell': '21.8', 'Exhausted memory B-cell': '17.1', 'Progenitor cell': '9.0', 'Memory T-reg': '0.5', 'Naive CD4 T-cell activated': '1.5', 'Naive CD8 T-cell activated': '2.2', 'Naive T-reg': '2.8'}
null
{'Adipose Tissue': 2.5924734219269103, 'Adrenal Gland': 17.54267054263566, 'Bladder': 2.490333333333333, 'Blood': 0.6585809095801938, 'Blood Vessel': 2.3506545318352057, 'Brain': 1.3721103785011357, 'Breast': 2.6128993464052286, 'Cervix Uteri': 3.6765578947368422, 'Colon': 3.133294736842106, 'Esophagus': 2.235712249134948, 'Fallopian Tube': 3.075, 'Heart': 1.095252288037166, 'Kidney': 1.5961022471910111, 'Liver': 3.5234774336283183, 'Lung': 4.063190311418685, 'Muscle': 1.3199622665006223, 'Nerve': 4.941733441033926, 'Ovary': 2.1193522222222225, 'Pancreas': 0.9325978658536588, 'Pituitary': 2.230408480565371, 'Prostate': 3.348035102040816, 'Salivary Gland': 1.7038827160493828, 'Skin': 2.0993314538419017, 'Small Intestine': 3.712585026737968, 'Spleen': 8.162435684647303, 'Stomach': 1.9815635097493036, 'Testis': 10.827382271468144, 'Thyroid': 3.5891656967840735, 'Uterus': 3.5583985915492957, 'Vagina': 2.5643858974358973}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
74.762927
0.468805
1,940
O60260
Q96P20
33527027
UbiBrowser
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
NLRP3
MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW
Homo sapiens
Cytoplasm, cytosol, Inflammasome, Cytoplasm, cytoskeleton, microtubule organizing center, Golgi apparatus membrane, Endoplasmic reticulum, Mitochondrion, Secreted, Nucleus
Not found
{}
2NAQ, 3QF2, 6NPY, 7ALV, 7PZC, 7PZD, 7VTP, 7ZGU, 8EJ4, 8ERT, 8ETR, 8RI2, 8SWF, 8SWK, 8SXN, 8WSM
{'Adipose Tissue': 4.698878322259136, 'Adrenal Gland': 1.0227939147286822, 'Bladder': 1.1805714285714286, 'Blood': 33.46069910441335, 'Blood Vessel': 2.6312273782771536, 'Brain': 1.5930649735049205, 'Breast': 1.9766877995642704, 'Cervix Uteri': 1.0085526315789477, 'Colon': 1.4169449293966625, 'Esophagus': 0.8502012733564013, 'Fallopian Tube': 3.2701555555555557, 'Heart': 0.7041933681765389, 'Kidney': 0.6705122471910112, 'Liver': 0.3818703097345132, 'Lung': 9.399427335640135, 'Muscle': 0.4159024408468244, 'Nerve': 3.3394169628432957, 'Ovary': 0.9351643333333332, 'Pancreas': 0.321316737804878, 'Pituitary': 1.165482332155477, 'Prostate': 1.1363395918367347, 'Salivary Gland': 1.2864487654320986, 'Skin': 0.5641537954671089, 'Small Intestine': 2.4529085561497324, 'Spleen': 7.132219917012448, 'Stomach': 1.1931440111420613, 'Testis': 0.7674373961218837, 'Thyroid': 1.143772741194487, 'Uterus': 1.2846866197183098, 'Vagina': 1.0036647435897434}
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0.76, 0.7, 0.05, 0.48, 0.08, 0.46, 0.1, 0.78, 0.7, 0.95, 0.94]
null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
81.560125
0.332741
482
O60260
Q96QK1
29893854
UbiBrowser
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
VPS35
MPTTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRLALFAHREDGPGIPADIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLVSTLIQDQPDQPVEDPDPEDFADEQSLVGRFIHLLRSEDPDQQYLILNTARKHFGAGGNQRIRFTLPPLVFAAYQLAFRYKENSKVDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRLRRESPESEGPIYEGLIL
Homo sapiens
Cytoplasm, Membrane, Endosome, Early endosome, Late endosome
Low tissue specificity
{'Ciliated cells': '143.0', 'Basal respiratory cells': '92.1', 'Club cells': '81.7', 'Ionocytes': '64.8', 'Mucus glandular cells': '95.0', 'Serous glandular cells': '72.7', 'Gastric mucus-secreting cells': '85.5', 'Proximal enterocytes': '148.2', 'Paneth cells': '103.8', 'Distal enterocytes': '65.5', 'Intestinal goblet cells': '72.9', 'Exocrine glandular cells': '-0.545', 'Basal prostatic cells': '71.7', 'Prostatic glandular cells': '69.5', 'Breast glandular cells': '0.359', 'Breast myoepithelial cells': '0.434', 'Glandular and luminal cells': '95.0', 'Secretory cells': '86.0', 'Basal keratinocytes': '90.3', 'Suprabasal keratinocytes': '129.1', 'Basal squamous epithelial cells': '79.1', 'Squamous epithelial cells': '101.7', 'Alveolar cells type 1': '0.062', 'Alveolar cells type 2': '0.161', 'Salivary duct cells': '97.6', 'Ductal cells': '0.627', 'Hepatocytes': '0.612', 'Cholangiocytes': '47.7', 'Proximal tubular cells': '0.289', 'Distal tubular cells': '55.3', 'Collecting duct cells': '66.1', 'Mesothelial cells': '0.256', 'Sertoli cells': '0.603', 'Granulosa cells': '86.4', 'Enteroendocrine cells': '63.1', 'Pancreatic endocrine cells': '78.1', 'Leydig cells': '0.498', 'Excitatory neurons': '41.7', 'Inhibitory neurons': '40.7', 'Cone photoreceptor cells': '86.7', 'Rod photoreceptor cells': '69.0', 'Bipolar cells': '50.9', 'Horizontal cells': '70.5', 'Astrocytes': '19.5', 'Oligodendrocyte precursor cells': '26.9', 'Oligodendrocytes': '29.1', 'Microglial cells': '28.6', 'Muller glia cells': '69.6', 'Schwann cells': '0.130', 'Spermatogonia': '0.657', 'Spermatocytes': '0.600', 'Early spermatids': '-0.205', 'Late spermatids': '-0.532', 'Oocytes': '118.4', 'Cytotrophoblasts': '138.1', 'Syncytiotrophoblasts': '133.1', 'Extravillous trophoblasts': '107.1', 'Endothelial cells': '62.8', 'Lymphatic endothelial cells': '72.6', 'Cardiomyocytes': '0.671', 'Skeletal myocytes': '-0.032', 'Smooth muscle cells': '65.5', 'Adipocytes': '63.4', 'Melanocytes': '0.333', 'Fibroblasts': '70.2', 'Peritubular cells': '0.375', 'Endometrial stromal cells': '94.0', 'Ovarian stromal cells': '71.8', 'Undifferentiated cells': '104.6', 'T-cells': '54.1', 'B-cells': '86.8', 'Plasma cells': '47.0', 'Nk-cells': '42.3', 'Granulocytes': '88.2', 'Monocytes': '227.4', 'Macrophages': '112.5', 'Hofbauer cells': '125.8', 'Kupffer cells': '80.4', 'Dendritic cells': '56.8', 'Langerhans cells': '0.349', 'Erythroid cells': '0.000', 'Adipocytes (Subcutaneous)': '0.072', 'Adipocytes (Visceral)': '-0.099', 'Breast glandular cells (progenitors)': '0.262', 'Adipocytes (Breast)': '-0.251', 'Colon enterocytes': '-0.135', 'Colon enteroendocrine cells': '0.291', 'Enteric glia cells': '-0.046', 'Mitotic cells (Colon)': '-0.063', 'Mitotic cells (Heart)': '0.496', 'Podocytes': '0.013', 'Ascending Loop of Henle cells': '0.444', 'Intercalated cells': '0.099', 'Cholangiocyte': '0.406', 'NK-cells (Liver)': '-0.325', 'Respiratory ciliated cells': '0.100', 'Mitotic cells (Lung)': '0.267', 'NK-cells (Lung)': '-0.084', 'B-cells (Lung)': '-0.178', 'Alpha cells': '0.371', 'Beta cells': '0.216', 'Prostate glandular cells': '-0.208', 'Prostate basal glandular cells': '0.046', 'Urothelial cells': '0.043', 'Keratinocyte (other)': '0.437', 'Keratinocyte (granular)': '-0.100', 'Hair cortex cells': '-0.012', 'Inner root sheath cells': '0.062', 'Outer root sheath cells': '0.189', 'Sebaceous gland cells': '0.104', 'Eccrine sweat gland cells': '-0.050', 'Adipocytes (Skin)': '-0.142', 'Mitotic cells (Skin)': '0.521', 'Parietal cells': '-0.396', 'Chief cells': '-0.407', 'Gastric mucous cells': '-0.012', 'Gastric enteroendocrine cells': '-0.292', 'Mitotic cells (Stomach)': '0.373', 'Parafollicular cells': '0.098', 'Thyroid glandular cells': '0.598', 'Mitotic cells (Thyroid)': '0.148', 'Adrenal cortex cells': '0.684', 'Adrenal medulla cells': '0.070', 'Mitotic cells (Adrenal gland)': '0.478', 'Minor salivary glandular cells': '0.404', 'Minor salivary gland ductal cells': '-0.060', 'Minor salivary gland basal cells': '0.513', 'Mitotic cells (Minor salivary gland)': '0.571', 'Adipocytes (Minor salivary gland)': '0.096', 'Somatotropes': '0.038', 'Lactotropes': '0.057', 'Gonadotropes': '0.253', 'Corticotropes': '-0.162', 'Thyrotropes': '0.248', 'Undifferentiated cells (Pituitary gland)': '0.306', 'Mitotic cells (Spleen)': '-0.029', 'Platelets': '0.043', 'Erythrocytes': '-0.225', 'Hematopoietic stem cells': '-0.043', 'B-cells (Spleen)': '0.239', 'NK-cells (Spleen)': '0.160', 'Amygdala excitatory': '64.4', 'Cerebellar inhibitory': '67.4', 'Cge interneuron': '68.0', 'Deep-layer corticothalamic and 6b': '62.0', 'Deep-layer intratelencephalic': '65.9', 'Deep-layer near-projecting': '71.9', 'Eccentric medium spiny neuron': '65.8', 'Hippocampal ca1-3': '59.0', 'Hippocampal ca4': '66.1', 'Hippocampal dentate gyrus': '78.5', 'Lamp5-lhx6 and chandelier': '71.8', 'Lower rhombic lip': '89.6', 'Mammillary body': '81.8', 'Medium spiny neuron': '65.8', 'Mge interneuron': '64.8', 'Midbrain-derived inhibitory': '66.1', 'Miscellaneous': '70.8', 'Splatter': '82.7', 'Thalamic excitatory': '79.4', 'Upper rhombic lip': '64.3', 'Upper-layer intratelencephalic': '67.3', 'Astrocyte': '37.3', 'Bergmann glia': '50.9', 'Central nervous system macrophage': '89.7', 'Choroid plexus epithelial cell': '50.9', 'Committed oligodendrocyte precursor': '47.9', 'Ependymal cell': '80.2', 'Oligodendrocyte': '50.7', 'Oligodendrocyte precursor cell': '48.8', 'Endothelial cell': '42.6', 'Pericyte': '54.2', 'Vascular associated smooth muscle cell': '55.0', 'Fibroblast': '41.9', 'Leukocyte': '58.6', 'Basophil': '8.8', 'Eosinophil': '1.3', 'Neutrophil': '12.0', 'Classical monocyte': '44.3', 'Non-classical monocyte': '113.2', 'Intermediate monocyte': '12.0', 'T-reg': '5.7', 'GdT-cell': '0.7', 'MAIT T-cell': '6.6', 'Memory CD4 T-cell': '0.7', 'Naive CD4 T-cell': '40.9', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '30.6', 'Memory B-cell': '0.8', 'Naive B-cell': '47.6', 'Plasmacytoid DC': '5.8', 'Myeloid DC': '10.4', 'NK-cell': '25.5', 'Total PBMC': '6.7', 'Vd2 gdTCR': '8.4', 'Memory CD4 T-cell Th1\\/Th17': '33.2', 'Memory CD4 T-cell Th17': '34.9', 'Memory CD4 T-cell Th2': '36.1', 'Non-Vd2 gdTCR': '6.5', 'Memory CD4 T-cell Th1': '29.5', 'Memory CD4 T-cell TFH': '34.4', 'Terminal effector memory CD4 T-cell': '5.0', 'Central memory CD8 T-cell': '6.9', 'Effector memory CD8 T-cell': '7.5', 'Terminal effector memory CD8 T-cell': '7.8', 'Non-switched memory B-cell': '11.5', 'Plasmablast': '4.0', 'Switched memory B-cell': '10.1', 'Exhausted memory B-cell': '8.4', 'Progenitor cell': '6.8', 'Memory T-reg': '28.0', 'Naive CD4 T-cell activated': '58.6', 'Naive CD8 T-cell activated': '60.5', 'Naive T-reg': '42.7'}
2R17, 5F0J, 5F0K, 5F0L, 5F0M, 5F0P, 5OSH, 5OSI, 7BLN, 7BLO, 8R02, 8R0J, 8RKS
{'Adipose Tissue': 27.107558970099667, 'Adrenal Gland': 21.40024418604651, 'Bladder': 36.28809523809524, 'Blood': 26.916494079655543, 'Blood Vessel': 34.61241423220974, 'Brain': 22.83030734292203, 'Breast': 27.03065359477124, 'Cervix Uteri': 33.93526315789474, 'Colon': 26.97588831835687, 'Esophagus': 29.091782006920415, 'Fallopian Tube': 32.15888888888889, 'Heart': 14.133124738675958, 'Kidney': 14.04326966292135, 'Liver': 6.114517699115044, 'Lung': 26.424809688581316, 'Muscle': 11.39456787048568, 'Nerve': 34.742084006462036, 'Ovary': 31.096055555555555, 'Pancreas': 8.674801829268294, 'Pituitary': 23.836996466431096, 'Prostate': 23.955302040816328, 'Salivary Gland': 25.947345679012347, 'Skin': 32.776987285793254, 'Small Intestine': 25.954010695187165, 'Spleen': 23.834095435684645, 'Stomach': 21.997231197771587, 'Testis': 37.345872576177285, 'Thyroid': 24.64127105666156, 'Uterus': 34.30133802816901, 'Vagina': 33.04365384615385}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
90.952601
0.301445
809
O60260
Q99497
15525661, 20634198, BioGrid E3Net
UbiNet, UbiBrowser, 31181401
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
PARK7
MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVLKD
Homo sapiens
Cell membrane, Cytoplasm, Nucleus, Membrane raft, Mitochondrion, Endoplasmic reticulum
Low tissue specificity
{'Ciliated cells': '322.7', 'Basal respiratory cells': '660.0', 'Club cells': '332.2', 'Ionocytes': '394.7', 'Mucus glandular cells': '192.7', 'Serous glandular cells': '363.2', 'Gastric mucus-secreting cells': '151.5', 'Proximal enterocytes': '235.6', 'Paneth cells': '196.0', 'Distal enterocytes': '165.7', 'Intestinal goblet cells': '213.3', 'Exocrine glandular cells': '-0.714', 'Basal prostatic cells': '410.8', 'Prostatic glandular cells': '450.3', 'Breast glandular cells': '-0.048', 'Breast myoepithelial cells': '-0.206', 'Glandular and luminal cells': '226.5', 'Secretory cells': '378.4', 'Basal keratinocytes': '250.4', 'Suprabasal keratinocytes': '186.2', 'Basal squamous epithelial cells': '209.2', 'Squamous epithelial cells': '211.5', 'Alveolar cells type 1': '-0.187', 'Alveolar cells type 2': '-0.085', 'Salivary duct cells': '237.3', 'Ductal cells': '0.541', 'Hepatocytes': '0.622', 'Cholangiocytes': '246.1', 'Proximal tubular cells': '0.258', 'Distal tubular cells': '842.1', 'Collecting duct cells': '235.3', 'Mesothelial cells': '0.145', 'Sertoli cells': '0.289', 'Granulosa cells': '297.0', 'Enteroendocrine cells': '242.8', 'Pancreatic endocrine cells': '509.4', 'Leydig cells': '0.397', 'Excitatory neurons': '18.9', 'Inhibitory neurons': '21.9', 'Cone photoreceptor cells': '339.8', 'Rod photoreceptor cells': '150.9', 'Bipolar cells': '196.0', 'Horizontal cells': '121.5', 'Astrocytes': '22.0', 'Oligodendrocyte precursor cells': '17.0', 'Oligodendrocytes': '33.5', 'Microglial cells': '20.6', 'Muller glia cells': '778.7', 'Schwann cells': '0.044', 'Spermatogonia': '0.413', 'Spermatocytes': '0.281', 'Early spermatids': '0.011', 'Late spermatids': '-0.308', 'Oocytes': '333.8', 'Cytotrophoblasts': '603.0', 'Syncytiotrophoblasts': '453.4', 'Extravillous trophoblasts': '651.0', 'Endothelial cells': '237.9', 'Lymphatic endothelial cells': '288.6', 'Cardiomyocytes': '0.737', 'Skeletal myocytes': '-0.067', 'Smooth muscle cells': '336.4', 'Adipocytes': '236.2', 'Melanocytes': '0.030', 'Fibroblasts': '313.4', 'Peritubular cells': '0.276', 'Endometrial stromal cells': '280.3', 'Ovarian stromal cells': '399.0', 'Undifferentiated cells': '327.5', 'T-cells': '238.8', 'B-cells': '191.7', 'Plasma cells': '347.4', 'Nk-cells': '233.6', 'Granulocytes': '266.9', 'Monocytes': '189.5', 'Macrophages': '235.8', 'Hofbauer cells': '432.1', 'Kupffer cells': '188.2', 'Dendritic cells': '572.7', 'Langerhans cells': '0.008', 'Erythroid cells': '-0.090', 'Adipocytes (Subcutaneous)': '0.328', 'Adipocytes (Visceral)': '0.218', 'Breast glandular cells (progenitors)': '-0.176', 'Adipocytes (Breast)': '0.273', 'Colon enterocytes': '-0.313', 'Colon enteroendocrine cells': '0.191', 'Enteric glia cells': '0.097', 'Mitotic cells (Colon)': '-0.185', 'Mitotic cells (Heart)': '0.468', 'Podocytes': '0.139', 'Ascending Loop of Henle cells': '0.384', 'Intercalated cells': '0.144', 'Cholangiocyte': '0.361', 'NK-cells (Liver)': '-0.367', 'Respiratory ciliated cells': '0.003', 'Mitotic cells (Lung)': '0.161', 'NK-cells (Lung)': '-0.165', 'B-cells (Lung)': '-0.216', 'Alpha cells': '0.386', 'Beta cells': '0.163', 'Prostate glandular cells': '0.292', 'Prostate basal glandular cells': '0.103', 'Urothelial cells': '-0.161', 'Keratinocyte (other)': '-0.291', 'Keratinocyte (granular)': '-0.380', 'Hair cortex cells': '0.322', 'Inner root sheath cells': '0.369', 'Outer root sheath cells': '0.418', 'Sebaceous gland cells': '0.200', 'Eccrine sweat gland cells': '0.377', 'Adipocytes (Skin)': '0.280', 'Mitotic cells (Skin)': '0.202', 'Parietal cells': '-0.643', 'Chief cells': '-0.457', 'Gastric mucous cells': '-0.430', 'Gastric enteroendocrine cells': '-0.440', 'Mitotic cells (Stomach)': '0.057', 'Parafollicular cells': '0.126', 'Thyroid glandular cells': '0.607', 'Mitotic cells (Thyroid)': '-0.102', 'Adrenal cortex cells': '0.488', 'Adrenal medulla cells': '0.030', 'Mitotic cells (Adrenal gland)': '0.383', 'Minor salivary glandular cells': '0.441', 'Minor salivary gland ductal cells': '0.107', 'Minor salivary gland basal cells': '-0.048', 'Mitotic cells (Minor salivary gland)': '0.090', 'Adipocytes (Minor salivary gland)': '0.110', 'Somatotropes': '0.109', 'Lactotropes': '0.103', 'Gonadotropes': '-0.021', 'Corticotropes': '0.025', 'Thyrotropes': '0.201', 'Undifferentiated cells (Pituitary gland)': '0.147', 'Mitotic cells (Spleen)': '-0.140', 'Platelets': '-0.132', 'Erythrocytes': '-0.090', 'Hematopoietic stem cells': '-0.166', 'B-cells (Spleen)': '0.146', 'NK-cells (Spleen)': '0.012', 'Amygdala excitatory': '22.3', 'Cerebellar inhibitory': '56.1', 'Cge interneuron': '55.0', 'Deep-layer corticothalamic and 6b': '33.0', 'Deep-layer intratelencephalic': '31.6', 'Deep-layer near-projecting': '36.1', 'Eccentric medium spiny neuron': '30.8', 'Hippocampal ca1-3': '27.0', 'Hippocampal ca4': '91.0', 'Hippocampal dentate gyrus': '54.6', 'Lamp5-lhx6 and chandelier': '46.4', 'Lower rhombic lip': '63.3', 'Mammillary body': '26.6', 'Medium spiny neuron': '27.5', 'Mge interneuron': '36.7', 'Midbrain-derived inhibitory': '45.1', 'Miscellaneous': '34.8', 'Splatter': '47.7', 'Thalamic excitatory': '41.5', 'Upper rhombic lip': '62.7', 'Upper-layer intratelencephalic': '34.2', 'Astrocyte': '33.9', 'Bergmann glia': '55.0', 'Central nervous system macrophage': '36.6', 'Choroid plexus epithelial cell': '65.6', 'Committed oligodendrocyte precursor': '48.4', 'Ependymal cell': '60.3', 'Oligodendrocyte': '56.1', 'Oligodendrocyte precursor cell': '37.3', 'Endothelial cell': '50.6', 'Pericyte': '77.0', 'Vascular associated smooth muscle cell': '79.7', 'Fibroblast': '45.4', 'Leukocyte': '49.8', 'Basophil': '69.2', 'Eosinophil': '395.4', 'Neutrophil': '107.2', 'Classical monocyte': '144.4', 'Non-classical monocyte': '124.5', 'Intermediate monocyte': '227.4', 'T-reg': '236.7', 'GdT-cell': '486.1', 'MAIT T-cell': '189.7', 'Memory CD4 T-cell': '479.8', 'Naive CD4 T-cell': '110.3', 'Memory CD8 T-cell': '577.7', 'Naive CD8 T-cell': '109.9', 'Memory B-cell': '485.7', 'Naive B-cell': '68.5', 'Plasmacytoid DC': '794.7', 'Myeloid DC': '271.1', 'NK-cell': '147.5', 'Total PBMC': '296.0', 'Vd2 gdTCR': '295.6', 'Memory CD4 T-cell TFH': '123.0', 'Memory CD4 T-cell Th2': '127.3', 'Memory CD4 T-cell Th17': '134.1', 'Memory CD4 T-cell Th1\\/Th17': '115.8', 'Non-Vd2 gdTCR': '212.9', 'Memory CD4 T-cell Th1': '123.0', 'Terminal effector memory CD4 T-cell': '182.9', 'Central memory CD8 T-cell': '197.2', 'Effector memory CD8 T-cell': '202.0', 'Terminal effector memory CD8 T-cell': '299.7', 'Switched memory B-cell': '169.3', 'Plasmablast': '315.4', 'Non-switched memory B-cell': '157.7', 'Exhausted memory B-cell': '209.2', 'Progenitor cell': '146.2', 'Memory T-reg': '182.0', 'Naive CD4 T-cell activated': '272.2', 'Naive CD8 T-cell activated': '377.3', 'Naive T-reg': '110.1'}
1J42, 1P5F, 1PDV, 1PDW, 1PE0, 1Q2U, 1SOA, 1UCF, 2OR3, 2R1T, 2R1U, 2R1V, 2RK3, 2RK4, 2RK6, 3B36, 3B38, 3B3A, 3BWE, 3CY6, 3CYF, 3CZ9, 3CZA, 3EZG, 3F71, 3SF8, 4BTE, 4MNT, 4MTC, 4N0M, 4N12, 4OGF, 4OQ4, 4P2G, 4P34, 4P35, 4P36, 4RKW, 4RKY, 4S0Z, 4ZGG, 5IP5, 5SY6, 5SY9, 5SYA, 6AF5, 6AF7, 6AF9, 6AFA, 6AFB, 6AFC, 6AFD, 6AFE, 6AFF, 6AFG, 6AFH, 6AFI, 6AFJ, 6AFL, 6E5Z, 6M8Z, 7C62, 7PA2, 7PA3, 8PPW, 8PQ0
{'Adipose Tissue': 185.79203488372093, 'Adrenal Gland': 239.41910852713175, 'Bladder': 191.8095238095238, 'Blood': 109.2892228202368, 'Blood Vessel': 256.7158052434457, 'Brain': 188.0909084027252, 'Breast': 192.48424836601308, 'Cervix Uteri': 211.57, 'Colon': 170.5653915275995, 'Esophagus': 164.19462283737025, 'Fallopian Tube': 213.16666666666663, 'Heart': 127.65317537746807, 'Kidney': 144.02022471910112, 'Liver': 108.76008849557522, 'Lung': 169.39134948096884, 'Muscle': 223.05840597758404, 'Nerve': 260.44006462035543, 'Ovary': 227.5994444444445, 'Pancreas': 78.50256097560975, 'Pituitary': 247.443109540636, 'Prostate': 212.62, 'Salivary Gland': 134.31925925925927, 'Skin': 155.921138750691, 'Small Intestine': 129.67882352941174, 'Spleen': 144.20601659751037, 'Stomach': 145.66178272980503, 'Testis': 150.65473684210525, 'Thyroid': 242.57044410413476, 'Uterus': 211.3887323943662, 'Vagina': 157.61384615384614}
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[0.99, 0.92, 0.52, 0.33, 0.28, 0.0, 0.0, 0.01, 0.0, 0.01, 0.03, 0.51, 0.1, 0.01, 0.08, 0.1, 0.49, 0.01, 0.03, 0.52, 0.17, 0.01, 0.1, 0.43, 0.01, 0.0, 0.44, 0.56, 0.11, 0.47, 0.04, 0.62, 0.11, 0.23, 0.05, 0.0, 0.01, 0.23, 0.97, 0.29, 0.65, 0.81, 0.58, 0.08, 0.44, 0.05, 0.38, 0.84, 0.64, 0.43, 0.62, 0.17, 0.76, 0.14, 0.52, 0.26, 0.09, 0.04, 0.71, 0.32, 0.03, 0.33, 0.62, 0.63, 0.48, 0.57, 0.06, 0.28, 0.0, 0.02, 0.01, 0.0, 0.02, 0.0, 0.1, 0.71, 0.56, 0.01, 0.01, 0.36, 0.28, 0.01, 0.17, 0.65, 0.17, 0.67, 0.4, 0.0, 0.45, 0.48, 0.08, 0.0, 0.3, 0.46, 0.04, 0.34, 0.75, 0.5, 0.74, 0.13, 0.06, 0.01, 0.0, 0.01, 0.0, 0.09, 0.05, 0.0, 0.0, 0.05, 0.0, 0.0, 0.19, 0.45, 0.03, 0.57, 0.0, 0.1, 0.4, 0.67, 0.11, 0.38, 0.0, 0.0, 0.0, 0.36, 0.57, 0.84, 0.09, 0.37, 0.82, 0.5, 0.0, 0.29, 0.64, 0.71, 0.62, 0.41, 0.05, 0.55, 0.2, 0.06, 0.7, 0.46, 0.48, 0.28, 0.11, 0.55, 0.4, 0.56, 0.41, 0.08, 0.0, 0.0, 0.0, 0.18, 0.07, 0.29, 0.73, 0.06, 0.0, 0.35, 0.38, 0.0, 0.0, 0.12, 0.23, 0.0, 0.0, 0.41, 0.46, 0.17, 0.34, 0.32, 0.68, 0.72, 0.28, 0.09, 0.54, 0.57, 0.06, 0.33, 0.71, 0.61, 0.23, 0.85, 0.32, 0.96, 0.86]
null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
98.415979
0.295979
2,780
O60260
Q99623
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
PHB2
MAQNLKDLAGRLPAGPRGMGTALKLLLGAGAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYPIIYDIRARPRKISSPTGSKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLITQRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEALSKNPGYIKLRKIRAAQNISKTIATSQNRIYLTADNLVLNLQDESFTRGSDSLIKGKK
Homo sapiens
Mitochondrion inner membrane, Cytoplasm, Nucleus, Cell membrane, Mitochondrion inner membrane, Mitochondrion inner membrane
Low tissue specificity
{'Ciliated cells': '68.2', 'Basal respiratory cells': '106.0', 'Club cells': '97.3', 'Ionocytes': '55.2', 'Mucus glandular cells': '76.7', 'Serous glandular cells': '112.8', 'Gastric mucus-secreting cells': '106.1', 'Proximal enterocytes': '213.6', 'Paneth cells': '110.2', 'Distal enterocytes': '143.0', 'Intestinal goblet cells': '112.3', 'Exocrine glandular cells': '-0.721', 'Basal prostatic cells': '100.1', 'Prostatic glandular cells': '98.6', 'Breast glandular cells': '0.426', 'Breast myoepithelial cells': '0.168', 'Glandular and luminal cells': '96.6', 'Secretory cells': '262.0', 'Basal keratinocytes': '132.4', 'Suprabasal keratinocytes': '121.5', 'Basal squamous epithelial cells': '233.4', 'Squamous epithelial cells': '237.1', 'Alveolar cells type 1': '-0.120', 'Alveolar cells type 2': '0.124', 'Salivary duct cells': '101.8', 'Ductal cells': '0.534', 'Hepatocytes': '0.362', 'Cholangiocytes': '74.4', 'Proximal tubular cells': '0.246', 'Distal tubular cells': '89.1', 'Collecting duct cells': '42.8', 'Mesothelial cells': '0.323', 'Sertoli cells': '0.665', 'Granulosa cells': '116.7', 'Enteroendocrine cells': '149.0', 'Pancreatic endocrine cells': '120.6', 'Leydig cells': '0.718', 'Excitatory neurons': '9.6', 'Inhibitory neurons': '11.0', 'Cone photoreceptor cells': '74.8', 'Rod photoreceptor cells': '47.6', 'Bipolar cells': '35.8', 'Horizontal cells': '26.4', 'Astrocytes': '13.9', 'Oligodendrocyte precursor cells': '11.8', 'Oligodendrocytes': '12.0', 'Microglial cells': '8.1', 'Muller glia cells': '87.1', 'Schwann cells': '0.006', 'Spermatogonia': '0.466', 'Spermatocytes': '0.003', 'Early spermatids': '-0.619', 'Late spermatids': '-0.738', 'Oocytes': '38.2', 'Cytotrophoblasts': '236.5', 'Syncytiotrophoblasts': '161.6', 'Extravillous trophoblasts': '284.5', 'Endothelial cells': '92.4', 'Lymphatic endothelial cells': '82.2', 'Cardiomyocytes': '0.708', 'Skeletal myocytes': '-0.085', 'Smooth muscle cells': '126.5', 'Adipocytes': '109.9', 'Melanocytes': '0.004', 'Fibroblasts': '108.1', 'Peritubular cells': '0.567', 'Endometrial stromal cells': '131.0', 'Ovarian stromal cells': '200.6', 'Undifferentiated cells': '264.3', 'T-cells': '99.6', 'B-cells': '139.6', 'Plasma cells': '159.4', 'Nk-cells': '89.3', 'Granulocytes': '112.6', 'Monocytes': '129.7', 'Macrophages': '103.9', 'Hofbauer cells': '152.2', 'Kupffer cells': '102.6', 'Dendritic cells': '110.5', 'Langerhans cells': '0.190', 'Erythroid cells': '0.003', 'Adipocytes (Subcutaneous)': '0.042', 'Adipocytes (Visceral)': '0.115', 'Breast glandular cells (progenitors)': '0.430', 'Adipocytes (Breast)': '-0.095', 'Colon enterocytes': '-0.222', 'Colon enteroendocrine cells': '0.074', 'Enteric glia cells': '-0.107', 'Mitotic cells (Colon)': '-0.193', 'Mitotic cells (Heart)': '0.469', 'Podocytes': '-0.057', 'Ascending Loop of Henle cells': '0.437', 'Intercalated cells': '0.056', 'Cholangiocyte': '0.143', 'NK-cells (Liver)': '-0.127', 'Respiratory ciliated cells': '-0.038', 'Mitotic cells (Lung)': '0.168', 'NK-cells (Lung)': '-0.343', 'B-cells (Lung)': '-0.225', 'Alpha cells': '0.324', 'Beta cells': '0.181', 'Prostate glandular cells': '-0.016', 'Prostate basal glandular cells': '0.321', 'Urothelial cells': '0.235', 'Keratinocyte (other)': '-0.115', 'Keratinocyte (granular)': '0.071', 'Hair cortex cells': '0.025', 'Inner root sheath cells': '0.062', 'Outer root sheath cells': '0.065', 'Sebaceous gland cells': '0.420', 'Eccrine sweat gland cells': '-0.078', 'Adipocytes (Skin)': '0.114', 'Mitotic cells (Skin)': '0.076', 'Parietal cells': '-0.555', 'Chief cells': '-0.417', 'Gastric mucous cells': '-0.300', 'Gastric enteroendocrine cells': '-0.365', 'Mitotic cells (Stomach)': '0.106', 'Parafollicular cells': '0.107', 'Thyroid glandular cells': '0.347', 'Mitotic cells (Thyroid)': '-0.063', 'Adrenal cortex cells': '0.256', 'Adrenal medulla cells': '-0.078', 'Mitotic cells (Adrenal gland)': '0.187', 'Minor salivary glandular cells': '0.578', 'Minor salivary gland ductal cells': '0.030', 'Minor salivary gland basal cells': '0.347', 'Mitotic cells (Minor salivary gland)': '0.413', 'Adipocytes (Minor salivary gland)': '0.242', 'Somatotropes': '0.165', 'Lactotropes': '0.094', 'Gonadotropes': '-0.055', 'Corticotropes': '-0.071', 'Thyrotropes': '0.088', 'Undifferentiated cells (Pituitary gland)': '0.070', 'Mitotic cells (Spleen)': '-0.196', 'Platelets': '-0.240', 'Erythrocytes': '-0.195', 'Hematopoietic stem cells': '-0.222', 'B-cells (Spleen)': '0.532', 'NK-cells (Spleen)': '0.138', 'Amygdala excitatory': '9.8', 'Cerebellar inhibitory': '21.3', 'Cge interneuron': '17.4', 'Deep-layer corticothalamic and 6b': '10.9', 'Deep-layer intratelencephalic': '10.6', 'Deep-layer near-projecting': '13.4', 'Eccentric medium spiny neuron': '13.4', 'Hippocampal ca1-3': '13.0', 'Hippocampal ca4': '14.8', 'Hippocampal dentate gyrus': '10.3', 'Lamp5-lhx6 and chandelier': '16.8', 'Lower rhombic lip': '16.5', 'Mammillary body': '10.6', 'Medium spiny neuron': '11.9', 'Mge interneuron': '14.6', 'Midbrain-derived inhibitory': '17.8', 'Miscellaneous': '13.3', 'Splatter': '15.1', 'Thalamic excitatory': '16.0', 'Upper rhombic lip': '23.5', 'Upper-layer intratelencephalic': '11.9', 'Astrocyte': '17.0', 'Bergmann glia': '22.1', 'Central nervous system macrophage': '18.3', 'Choroid plexus epithelial cell': '16.4', 'Committed oligodendrocyte precursor': '19.5', 'Ependymal cell': '22.2', 'Oligodendrocyte': '21.4', 'Oligodendrocyte precursor cell': '20.4', 'Endothelial cell': '25.1', 'Pericyte': '39.8', 'Vascular associated smooth muscle cell': '37.2', 'Fibroblast': '22.2', 'Leukocyte': '34.5', 'Basophil': '43.6', 'Eosinophil': '44.0', 'Neutrophil': '58.2', 'Classical monocyte': '142.3', 'Non-classical monocyte': '154.2', 'Intermediate monocyte': '172.8', 'T-reg': '134.6', 'GdT-cell': '84.4', 'MAIT T-cell': '173.5', 'Memory CD4 T-cell': '96.5', 'Naive CD4 T-cell': '192.0', 'Memory CD8 T-cell': '98.1', 'Naive CD8 T-cell': '207.6', 'Memory B-cell': '103.2', 'Naive B-cell': '158.0', 'Plasmacytoid DC': '210.2', 'Myeloid DC': '221.8', 'NK-cell': '154.1', 'Total PBMC': '155.8', 'Vd2 gdTCR': '140.8', 'Memory CD4 T-cell Th1\\/Th17': '202.0', 'Memory CD4 T-cell Th17': '232.4', 'Memory CD4 T-cell Th2': '227.3', 'Non-Vd2 gdTCR': '143.5', 'Memory CD4 T-cell Th1': '225.2', 'Memory CD4 T-cell TFH': '233.9', 'Terminal effector memory CD4 T-cell': '122.9', 'Central memory CD8 T-cell': '135.3', 'Effector memory CD8 T-cell': '146.5', 'Terminal effector memory CD8 T-cell': '139.7', 'Non-switched memory B-cell': '164.9', 'Plasmablast': '338.3', 'Switched memory B-cell': '193.9', 'Exhausted memory B-cell': '145.6', 'Progenitor cell': '157.5', 'Memory T-reg': '248.5', 'Naive CD4 T-cell activated': '265.1', 'Naive CD8 T-cell activated': '328.7', 'Naive T-reg': '205.4'}
6IQE, 8J4I
{'Adipose Tissue': 200.53760797342193, 'Adrenal Gland': 200.73542635658913, 'Bladder': 225.06666666666663, 'Blood': 151.4497556512379, 'Blood Vessel': 189.83968539325843, 'Brain': 73.93479182437548, 'Breast': 209.94124183006537, 'Cervix Uteri': 293.74210526315784, 'Colon': 226.1511553273427, 'Esophagus': 204.9675501730104, 'Fallopian Tube': 269.64444444444445, 'Heart': 94.56073170731706, 'Kidney': 112.09460674157305, 'Liver': 144.27283185840707, 'Lung': 165.85079584775085, 'Muscle': 176.66632627646325, 'Nerve': 192.75638126009693, 'Ovary': 393.94444444444446, 'Pancreas': 116.49881097560976, 'Pituitary': 135.12480565371024, 'Prostate': 204.04244897959185, 'Salivary Gland': 162.42148148148146, 'Skin': 244.83449419568825, 'Small Intestine': 185.88877005347592, 'Spleen': 180.6859336099585, 'Stomach': 166.14877437325907, 'Testis': 83.79559556786704, 'Thyroid': 210.1040581929556, 'Uterus': 285.43802816901405, 'Vagina': 217.09935897435895}
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[0.86, 0.75, 0.82, 0.72, 0.71, 0.8, 0.68, 0.69, 0.67, 0.78, 0.85, 0.82, 0.86, 0.96, 0.63, 0.72, 0.93, 0.6, 0.62, 0.51, 0.57, 0.42, 0.54, 0.72, 0.71, 0.66, 0.63, 0.41, 0.49, 0.41, 0.55, 0.64, 0.53, 0.56, 0.28, 0.54, 0.67, 0.28, 0.21, 0.32, 0.12, 0.68, 0.03, 0.7, 0.5, 0.25, 0.19, 0.29, 0.01, 0.01, 0.06, 0.37, 0.17, 0.63, 0.82, 0.78, 0.27, 0.14, 0.31, 0.43, 0.97, 0.32, 0.29, 0.17, 0.57, 0.67, 0.33, 0.63, 0.2, 0.66, 0.22, 0.57, 0.24, 0.75, 0.5, 0.15, 0.48, 0.31, 0.15, 0.52, 0.03, 0.2, 0.23, 0.5, 0.46, 0.47, 0.69, 0.25, 0.57, 0.09, 0.52, 0.06, 0.64, 0.02, 0.43, 0.06, 0.6, 0.41, 0.84, 0.31, 0.58, 0.01, 0.45, 0.0, 0.06, 0.0, 0.33, 0.01, 0.24, 0.01, 0.35, 0.01, 0.2, 0.14, 0.75, 0.41, 0.0, 0.01, 0.28, 0.0, 0.26, 0.62, 0.6, 0.16, 0.24, 0.55, 0.65, 0.07, 0.22, 0.66, 0.75, 0.08, 0.01, 0.26, 0.57, 0.06, 0.0, 0.29, 0.54, 0.03, 0.0, 0.51, 0.42, 0.0, 0.0, 0.46, 0.54, 0.15, 0.34, 0.0, 0.51, 0.32, 0.01, 0.57, 0.8, 0.4, 0.37, 0.74, 0.59, 0.01, 0.14, 0.57, 0.3, 0.0, 0.42, 0.73, 0.22, 0.0, 0.38, 0.69, 0.49, 0.0, 0.76, 0.61, 0.34, 0.03, 0.05, 0.3, 0.14, 0.45, 0.32, 0.05, 0.24, 0.08, 0.39, 0.58, 0.27, 0.51, 0.2, 0.31, 0.88, 0.77, 0.21, 0.39, 0.51, 0.55, 0.45, 0.6, 0.55, 0.7, 0.54, 0.54, 0.5, 0.5, 0.41, 0.58, 0.43, 0.53, 0.68, 0.5, 0.6, 0.65, 0.69, 0.51, 0.59, 0.53, 0.43, 0.57, 0.55, 0.42, 0.6, 0.62, 0.64, 0.66, 0.45, 0.64, 0.58, 0.49, 0.6, 0.46, 0.56, 0.45, 0.61, 0.45, 0.56, 0.69, 0.59, 0.46, 0.44, 0.6, 0.52, 0.15, 0.44, 0.76, 0.59, 0.17, 0.5, 0.51, 0.19, 0.49, 0.49, 0.45, 0.36, 0.34, 0.6, 0.41, 0.13, 0.52, 0.58, 0.52, 0.4, 0.67, 0.66, 0.38, 0.79, 0.83, 0.48, 0.93, 0.62, 0.81, 0.51, 0.86, 0.53, 0.6, 0.79, 0.77, 0.38, 0.69, 0.44, 0.33, 0.33, 0.28, 0.8, 0.46, 0.6, 0.69, 0.25, 0.23, 0.63, 0.51, 0.1, 0.47, 0.58, 0.56, 0.52, 0.74, 0.75, 0.64, 0.91]
null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
85.713813
0.446421
2,388
O60260
Q99648
11078524
UbiBrowser
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
CDCrel-1
RPFPGDGGRGRLCRPPPRAPRAPATPRLWLGCGSGACPDCDAATAWGQFAQSGGWLGRPRGSTIPRDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ
Homo sapiens
Cytoplasm, cytoskeleton
Not found
{}
null
{}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
70.68777
0.516978
1,662
O60260
Q99714
25591737, 25583483
UbiNet, UbiBrowser, 31181401
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
HSD17B10
MAAACRSVKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVIRLDGAIRMQP
Homo sapiens
Mitochondrion, Mitochondrion matrix, mitochondrion nucleoid
Low tissue specificity
{'Ciliated cells': '31.7', 'Basal respiratory cells': '142.8', 'Club cells': '71.2', 'Ionocytes': '76.9', 'Mucus glandular cells': '33.3', 'Serous glandular cells': '97.8', 'Gastric mucus-secreting cells': '28.9', 'Proximal enterocytes': '84.9', 'Paneth cells': '67.3', 'Distal enterocytes': '115.0', 'Intestinal goblet cells': '62.9', 'Exocrine glandular cells': '-0.647', 'Basal prostatic cells': '67.5', 'Prostatic glandular cells': '55.4', 'Breast glandular cells': '-0.021', 'Breast myoepithelial cells': '-0.258', 'Glandular and luminal cells': '57.8', 'Secretory cells': '68.3', 'Basal keratinocytes': '119.8', 'Suprabasal keratinocytes': '216.1', 'Basal squamous epithelial cells': '55.0', 'Squamous epithelial cells': '96.4', 'Alveolar cells type 1': '-0.197', 'Alveolar cells type 2': '0.229', 'Salivary duct cells': '39.5', 'Ductal cells': '0.522', 'Hepatocytes': '0.581', 'Cholangiocytes': '103.0', 'Proximal tubular cells': '0.348', 'Distal tubular cells': '230.5', 'Collecting duct cells': '108.9', 'Mesothelial cells': '-0.059', 'Sertoli cells': '0.655', 'Granulosa cells': '63.7', 'Enteroendocrine cells': '102.1', 'Pancreatic endocrine cells': '159.6', 'Leydig cells': '0.728', 'Excitatory neurons': '2.4', 'Inhibitory neurons': '3.1', 'Cone photoreceptor cells': '6.8', 'Rod photoreceptor cells': '9.8', 'Bipolar cells': '10.7', 'Horizontal cells': '7.6', 'Astrocytes': '4.6', 'Oligodendrocyte precursor cells': '6.1', 'Oligodendrocytes': '5.8', 'Microglial cells': '3.6', 'Muller glia cells': '65.8', 'Schwann cells': '0.014', 'Spermatogonia': '0.470', 'Spermatocytes': '0.041', 'Early spermatids': '-0.575', 'Late spermatids': '-0.633', 'Oocytes': '28.7', 'Cytotrophoblasts': '188.8', 'Syncytiotrophoblasts': '144.5', 'Extravillous trophoblasts': '237.6', 'Endothelial cells': '57.5', 'Lymphatic endothelial cells': '69.0', 'Cardiomyocytes': '0.730', 'Skeletal myocytes': '-0.306', 'Smooth muscle cells': '76.7', 'Adipocytes': '43.7', 'Melanocytes': '0.370', 'Fibroblasts': '74.1', 'Peritubular cells': '0.507', 'Endometrial stromal cells': '67.2', 'Ovarian stromal cells': '96.3', 'Undifferentiated cells': '93.5', 'T-cells': '54.0', 'B-cells': '50.6', 'Plasma cells': '110.3', 'Nk-cells': '61.0', 'Granulocytes': '48.8', 'Monocytes': '74.2', 'Macrophages': '61.5', 'Hofbauer cells': '135.8', 'Kupffer cells': '61.7', 'Dendritic cells': '43.8', 'Langerhans cells': '0.215', 'Erythroid cells': '-0.089', 'Adipocytes (Subcutaneous)': '0.406', 'Adipocytes (Visceral)': '0.556', 'Breast glandular cells (progenitors)': '-0.133', 'Adipocytes (Breast)': '0.407', 'Colon enterocytes': '-0.145', 'Colon enteroendocrine cells': '0.166', 'Enteric glia cells': '-0.068', 'Mitotic cells (Colon)': '-0.151', 'Mitotic cells (Heart)': '0.467', 'Podocytes': '0.013', 'Ascending Loop of Henle cells': '0.365', 'Intercalated cells': '0.115', 'Cholangiocyte': '0.148', 'NK-cells (Liver)': '-0.214', 'Respiratory ciliated cells': '-0.088', 'Mitotic cells (Lung)': '0.174', 'NK-cells (Lung)': '-0.327', 'B-cells (Lung)': '-0.318', 'Alpha cells': '0.302', 'Beta cells': '0.122', 'Prostate glandular cells': '0.156', 'Prostate basal glandular cells': '0.209', 'Urothelial cells': '0.001', 'Keratinocyte (other)': '0.236', 'Keratinocyte (granular)': '-0.033', 'Hair cortex cells': '0.228', 'Inner root sheath cells': '0.241', 'Outer root sheath cells': '0.221', 'Sebaceous gland cells': '0.203', 'Eccrine sweat gland cells': '-0.249', 'Adipocytes (Skin)': '-0.184', 'Mitotic cells (Skin)': '0.344', 'Parietal cells': '-0.590', 'Chief cells': '-0.456', 'Gastric mucous cells': '-0.383', 'Gastric enteroendocrine cells': '-0.459', 'Mitotic cells (Stomach)': '0.077', 'Parafollicular cells': '0.132', 'Thyroid glandular cells': '0.459', 'Mitotic cells (Thyroid)': '-0.157', 'Adrenal cortex cells': '0.291', 'Adrenal medulla cells': '-0.027', 'Mitotic cells (Adrenal gland)': '0.158', 'Minor salivary glandular cells': '0.092', 'Minor salivary gland ductal cells': '-0.292', 'Minor salivary gland basal cells': '0.709', 'Mitotic cells (Minor salivary gland)': '0.716', 'Adipocytes (Minor salivary gland)': '0.274', 'Somatotropes': '0.080', 'Lactotropes': '-0.065', 'Gonadotropes': '-0.012', 'Corticotropes': '-0.027', 'Thyrotropes': '0.074', 'Undifferentiated cells (Pituitary gland)': '0.132', 'Mitotic cells (Spleen)': '0.001', 'Platelets': '-0.009', 'Erythrocytes': '-0.098', 'Hematopoietic stem cells': '-0.021', 'B-cells (Spleen)': '0.118', 'NK-cells (Spleen)': '-0.148', 'Amygdala excitatory': '2.7', 'Cerebellar inhibitory': '6.6', 'Cge interneuron': '5.0', 'Deep-layer corticothalamic and 6b': '3.0', 'Deep-layer intratelencephalic': '3.2', 'Deep-layer near-projecting': '3.9', 'Eccentric medium spiny neuron': '3.2', 'Hippocampal ca1-3': '3.9', 'Hippocampal ca4': '7.0', 'Hippocampal dentate gyrus': '3.2', 'Lamp5-lhx6 and chandelier': '4.8', 'Lower rhombic lip': '7.1', 'Mammillary body': '4.6', 'Medium spiny neuron': '3.1', 'Mge interneuron': '4.3', 'Midbrain-derived inhibitory': '4.4', 'Miscellaneous': '3.8', 'Splatter': '6.3', 'Thalamic excitatory': '5.2', 'Upper rhombic lip': '6.0', 'Upper-layer intratelencephalic': '2.8', 'Astrocyte': '7.3', 'Bergmann glia': '12.1', 'Central nervous system macrophage': '5.0', 'Choroid plexus epithelial cell': '2.4', 'Committed oligodendrocyte precursor': '10.0', 'Ependymal cell': '9.4', 'Oligodendrocyte': '12.5', 'Oligodendrocyte precursor cell': '8.7', 'Endothelial cell': '11.8', 'Pericyte': '23.2', 'Vascular associated smooth muscle cell': '16.4', 'Fibroblast': '9.7', 'Leukocyte': '8.7', 'Basophil': '22.7', 'Eosinophil': '40.2', 'Neutrophil': '3.4', 'Classical monocyte': '97.0', 'Non-classical monocyte': '89.1', 'Intermediate monocyte': '76.1', 'T-reg': '59.3', 'GdT-cell': '84.6', 'MAIT T-cell': '46.3', 'Memory CD4 T-cell': '77.9', 'Naive CD4 T-cell': '57.1', 'Memory CD8 T-cell': '83.7', 'Naive CD8 T-cell': '68.8', 'Memory B-cell': '98.9', 'Naive B-cell': '40.3', 'Plasmacytoid DC': '63.6', 'Myeloid DC': '110.5', 'NK-cell': '92.7', 'Total PBMC': '87.5', 'Vd2 gdTCR': '73.2', 'Memory CD4 T-cell Th1\\/Th17': '66.7', 'Memory CD4 T-cell Th17': '79.9', 'Memory CD4 T-cell Th2': '71.4', 'Non-Vd2 gdTCR': '63.4', 'Memory CD4 T-cell Th1': '82.1', 'Memory CD4 T-cell TFH': '88.7', 'Terminal effector memory CD4 T-cell': '41.0', 'Central memory CD8 T-cell': '48.3', 'Effector memory CD8 T-cell': '56.4', 'Terminal effector memory CD8 T-cell': '87.1', 'Non-switched memory B-cell': '56.8', 'Plasmablast': '135.7', 'Switched memory B-cell': '60.8', 'Exhausted memory B-cell': '60.8', 'Progenitor cell': '43.3', 'Memory T-reg': '116.2', 'Naive CD4 T-cell activated': '122.0', 'Naive CD8 T-cell activated': '173.1', 'Naive T-reg': '60.2'}
1SO8, 1U7T, 2O23, 7ONU
{'Adipose Tissue': 86.13915282392026, 'Adrenal Gland': 124.38046511627908, 'Bladder': 87.2357142857143, 'Blood': 55.890922497308935, 'Blood Vessel': 121.34787265917603, 'Brain': 39.94418773656321, 'Breast': 90.39246187363834, 'Cervix Uteri': 101.13947368421051, 'Colon': 80.70116816431322, 'Esophagus': 110.8310519031142, 'Fallopian Tube': 103.75, 'Heart': 61.29052729384437, 'Kidney': 84.26876404494382, 'Liver': 144.20146017699113, 'Lung': 80.65432525951556, 'Muscle': 57.77838107098381, 'Nerve': 116.61318255250404, 'Ovary': 114.87638888888888, 'Pancreas': 40.477256097560975, 'Pituitary': 103.91865724381626, 'Prostate': 80.58220408163265, 'Salivary Gland': 67.61117283950617, 'Skin': 109.19775566611386, 'Small Intestine': 67.271871657754, 'Spleen': 71.00817427385893, 'Stomach': 73.27983286908078, 'Testis': 42.7621052631579, 'Thyroid': 119.74042879019908, 'Uterus': 105.27098591549296, 'Vagina': 93.37820512820512}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
96.636322
0.319119
2,518
O60260
Q99719
14559152, PRKN2_HUMAN
UbiNet, UbiBrowser, 31181401
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
SEPTIN5
MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ
Homo sapiens
Cytoplasm, Cytoplasm, cytoskeleton
Tissue enhanced (brain)
{'Ciliated cells': '0.0', 'Basal respiratory cells': '0.0', 'Club cells': '0.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.0', 'Serous glandular cells': '0.1', 'Gastric mucus-secreting cells': '1.2', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.143', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.574', 'Breast myoepithelial cells': '0.625', 'Glandular and luminal cells': '0.0', 'Secretory cells': '0.0', 'Basal keratinocytes': '0.4', 'Suprabasal keratinocytes': '0.7', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '10.1', 'Alveolar cells type 1': '-0.058', 'Alveolar cells type 2': '-0.557', 'Salivary duct cells': '0.0', 'Ductal cells': '0.236', 'Hepatocytes': '0.057', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.071', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.356', 'Sertoli cells': '-0.046', 'Granulosa cells': '0.2', 'Enteroendocrine cells': '1.1', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.050', 'Excitatory neurons': '0.2', 'Inhibitory neurons': '0.3', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.1', 'Microglial cells': '0.9', 'Muller glia cells': '0.1', 'Schwann cells': '0.551', 'Spermatogonia': '0.070', 'Spermatocytes': '-0.011', 'Early spermatids': '-0.067', 'Late spermatids': '0.121', 'Oocytes': '0.7', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '0.1', 'Lymphatic endothelial cells': '0.1', 'Cardiomyocytes': '0.799', 'Skeletal myocytes': '0.113', 'Smooth muscle cells': '1.2', 'Adipocytes': '0.0', 'Melanocytes': '0.182', 'Fibroblasts': '1.2', 'Peritubular cells': '0.138', 'Endometrial stromal cells': '1.3', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '0.0', 'T-cells': '0.0', 'B-cells': '0.0', 'Plasma cells': '0.1', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.0', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.297', 'Erythroid cells': '0.114', 'Adipocytes (Subcutaneous)': '-0.550', 'Adipocytes (Visceral)': '-0.477', 'Breast glandular cells (progenitors)': '0.501', 'Adipocytes (Breast)': '-0.549', 'Colon enterocytes': '-0.123', 'Colon enteroendocrine cells': '0.444', 'Enteric glia cells': '0.624', 'Mitotic cells (Colon)': '-0.193', 'Mitotic cells (Heart)': '0.335', 'Podocytes': '0.146', 'Ascending Loop of Henle cells': '0.474', 'Intercalated cells': '0.084', 'Cholangiocyte': '0.412', 'NK-cells (Liver)': '-0.009', 'Respiratory ciliated cells': '0.350', 'Mitotic cells (Lung)': '0.026', 'NK-cells (Lung)': '0.344', 'B-cells (Lung)': '0.230', 'Alpha cells': '0.453', 'Beta cells': '0.457', 'Prostate glandular cells': '0.107', 'Prostate basal glandular cells': '-0.167', 'Urothelial cells': '-0.172', 'Keratinocyte (other)': '0.638', 'Keratinocyte (granular)': '0.539', 'Hair cortex cells': '-0.443', 'Inner root sheath cells': '-0.416', 'Outer root sheath cells': '-0.454', 'Sebaceous gland cells': '-0.257', 'Eccrine sweat gland cells': '-0.528', 'Adipocytes (Skin)': '-0.488', 'Mitotic cells (Skin)': '0.045', 'Parietal cells': '-0.718', 'Chief cells': '-0.475', 'Gastric mucous cells': '-0.647', 'Gastric enteroendocrine cells': '-0.271', 'Mitotic cells (Stomach)': '-0.256', 'Parafollicular cells': '0.079', 'Thyroid glandular cells': '0.304', 'Mitotic cells (Thyroid)': '0.000', 'Adrenal cortex cells': '0.163', 'Adrenal medulla cells': '0.502', 'Mitotic cells (Adrenal gland)': '0.061', 'Minor salivary glandular cells': '-0.163', 'Minor salivary gland ductal cells': '-0.325', 'Minor salivary gland basal cells': '0.646', 'Mitotic cells (Minor salivary gland)': '0.670', 'Adipocytes (Minor salivary gland)': '0.192', 'Somatotropes': '-0.099', 'Lactotropes': '0.272', 'Gonadotropes': '0.271', 'Corticotropes': '0.541', 'Thyrotropes': '0.413', 'Undifferentiated cells (Pituitary gland)': '-0.071', 'Mitotic cells (Spleen)': '-0.144', 'Platelets': '0.063', 'Erythrocytes': '0.229', 'Hematopoietic stem cells': '0.074', 'B-cells (Spleen)': '-0.049', 'NK-cells (Spleen)': '0.163', 'Amygdala excitatory': '46.2', 'Cerebellar inhibitory': '26.2', 'Cge interneuron': '54.9', 'Deep-layer corticothalamic and 6b': '72.2', 'Deep-layer intratelencephalic': '71.9', 'Deep-layer near-projecting': '63.2', 'Eccentric medium spiny neuron': '45.7', 'Hippocampal ca1-3': '41.7', 'Hippocampal ca4': '25.6', 'Hippocampal dentate gyrus': '51.0', 'Lamp5-lhx6 and chandelier': '59.2', 'Lower rhombic lip': '28.1', 'Mammillary body': '21.9', 'Medium spiny neuron': '42.6', 'Mge interneuron': '45.0', 'Midbrain-derived inhibitory': '31.4', 'Miscellaneous': '61.8', 'Splatter': '29.5', 'Thalamic excitatory': '50.6', 'Upper rhombic lip': '30.8', 'Upper-layer intratelencephalic': '67.6', 'Astrocyte': '9.6', 'Bergmann glia': '6.6', 'Central nervous system macrophage': '3.5', 'Choroid plexus epithelial cell': '46.1', 'Committed oligodendrocyte precursor': '22.8', 'Ependymal cell': '27.6', 'Oligodendrocyte': '3.1', 'Oligodendrocyte precursor cell': '10.8', 'Endothelial cell': '6.8', 'Pericyte': '41.1', 'Vascular associated smooth muscle cell': '40.7', 'Fibroblast': '13.3', 'Leukocyte': '3.4', 'Basophil': '0.2', 'Eosinophil': '15.5', 'Neutrophil': '26.1', 'Classical monocyte': '0.1', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '1.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.5', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '0.3', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.9', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '22.3', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Non-Vd2 gdTCR': '0.4', 'Memory CD4 T-cell Th1': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Switched memory B-cell': '1.1', 'Plasmablast': '1.1', 'Non-switched memory B-cell': '1.6', 'Exhausted memory B-cell': '1.2', 'Progenitor cell': '52.1', 'Naive CD4 T-cell activated': '0.2', 'Naive CD8 T-cell activated': '0.8', 'Memory T-reg': '0.0', 'Naive T-reg': '0.0'}
6WCU
{}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
77.672764
0.435691
1,662
O60260
Q99733
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
NAP1L4
MADHSFSDGVPSDSVEAAKNASNTEKLTDQVMQNPRVLAALQERLDNVPHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESEWHSENEEEEKLAGDMKSKVVVTEKAAATAEEPDPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQPMSFVLEFHFEPNDYFTNSVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFNPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDEEGEDEDDAEINPKV
Homo sapiens
Nucleus, Cytoplasm
Low tissue specificity
{'Ciliated cells': '78.7', 'Basal respiratory cells': '71.1', 'Club cells': '71.8', 'Ionocytes': '53.0', 'Mucus glandular cells': '90.7', 'Serous glandular cells': '64.5', 'Gastric mucus-secreting cells': '48.9', 'Proximal enterocytes': '35.7', 'Paneth cells': '35.1', 'Distal enterocytes': '35.3', 'Intestinal goblet cells': '41.6', 'Exocrine glandular cells': '-0.698', 'Basal prostatic cells': '81.7', 'Prostatic glandular cells': '59.1', 'Breast glandular cells': '0.635', 'Breast myoepithelial cells': '0.631', 'Glandular and luminal cells': '86.7', 'Secretory cells': '62.6', 'Basal keratinocytes': '93.4', 'Suprabasal keratinocytes': '83.5', 'Basal squamous epithelial cells': '91.7', 'Squamous epithelial cells': '96.3', 'Alveolar cells type 1': '0.241', 'Alveolar cells type 2': '-0.205', 'Salivary duct cells': '121.2', 'Ductal cells': '0.667', 'Hepatocytes': '0.199', 'Cholangiocytes': '47.7', 'Proximal tubular cells': '0.274', 'Distal tubular cells': '144.5', 'Collecting duct cells': '81.7', 'Mesothelial cells': '0.279', 'Sertoli cells': '-0.276', 'Granulosa cells': '51.5', 'Enteroendocrine cells': '45.3', 'Pancreatic endocrine cells': '86.6', 'Leydig cells': '-0.360', 'Excitatory neurons': '35.7', 'Inhibitory neurons': '54.2', 'Cone photoreceptor cells': '68.0', 'Rod photoreceptor cells': '54.1', 'Bipolar cells': '75.3', 'Horizontal cells': '64.2', 'Astrocytes': '53.3', 'Oligodendrocyte precursor cells': '57.1', 'Oligodendrocytes': '116.6', 'Microglial cells': '36.7', 'Muller glia cells': '63.7', 'Schwann cells': '0.111', 'Spermatogonia': '0.056', 'Spermatocytes': '0.403', 'Early spermatids': '0.729', 'Late spermatids': '0.401', 'Oocytes': '144.1', 'Cytotrophoblasts': '107.5', 'Syncytiotrophoblasts': '93.9', 'Extravillous trophoblasts': '114.4', 'Endothelial cells': '54.4', 'Lymphatic endothelial cells': '77.9', 'Cardiomyocytes': '0.748', 'Skeletal myocytes': '-0.098', 'Smooth muscle cells': '55.2', 'Adipocytes': '51.5', 'Melanocytes': '0.195', 'Fibroblasts': '55.1', 'Peritubular cells': '-0.248', 'Endometrial stromal cells': '63.9', 'Ovarian stromal cells': '63.1', 'Undifferentiated cells': '64.4', 'T-cells': '132.5', 'B-cells': '59.1', 'Plasma cells': '83.6', 'Nk-cells': '130.2', 'Granulocytes': '85.2', 'Monocytes': '35.3', 'Macrophages': '44.5', 'Hofbauer cells': '40.6', 'Kupffer cells': '37.5', 'Dendritic cells': '37.6', 'Langerhans cells': '0.286', 'Erythroid cells': '-0.001', 'Adipocytes (Subcutaneous)': '0.041', 'Adipocytes (Visceral)': '0.020', 'Breast glandular cells (progenitors)': '0.503', 'Adipocytes (Breast)': '-0.497', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.187', 'Enteric glia cells': '0.256', 'Mitotic cells (Colon)': '-0.214', 'Mitotic cells (Heart)': '0.497', 'Podocytes': '-0.033', 'Ascending Loop of Henle cells': '0.487', 'Intercalated cells': '0.084', 'Cholangiocyte': '0.274', 'NK-cells (Liver)': '-0.195', 'Respiratory ciliated cells': '0.202', 'Mitotic cells (Lung)': '0.101', 'NK-cells (Lung)': '0.280', 'B-cells (Lung)': '0.092', 'Alpha cells': '0.456', 'Beta cells': '0.302', 'Prostate glandular cells': '-0.204', 'Prostate basal glandular cells': '0.253', 'Urothelial cells': '0.369', 'Keratinocyte (other)': '0.182', 'Keratinocyte (granular)': '-0.289', 'Hair cortex cells': '0.082', 'Inner root sheath cells': '0.129', 'Outer root sheath cells': '0.354', 'Sebaceous gland cells': '0.146', 'Eccrine sweat gland cells': '0.068', 'Adipocytes (Skin)': '-0.026', 'Mitotic cells (Skin)': '0.525', 'Parietal cells': '-0.484', 'Chief cells': '-0.522', 'Gastric mucous cells': '-0.211', 'Gastric enteroendocrine cells': '-0.338', 'Mitotic cells (Stomach)': '0.182', 'Parafollicular cells': '0.117', 'Thyroid glandular cells': '0.542', 'Mitotic cells (Thyroid)': '0.025', 'Adrenal cortex cells': '0.406', 'Adrenal medulla cells': '0.072', 'Mitotic cells (Adrenal gland)': '0.121', 'Minor salivary glandular cells': '0.606', 'Minor salivary gland ductal cells': '0.373', 'Minor salivary gland basal cells': '0.175', 'Mitotic cells (Minor salivary gland)': '0.205', 'Adipocytes (Minor salivary gland)': '0.123', 'Somatotropes': '0.334', 'Lactotropes': '-0.005', 'Gonadotropes': '0.241', 'Corticotropes': '-0.104', 'Thyrotropes': '0.025', 'Undifferentiated cells (Pituitary gland)': '0.091', 'Mitotic cells (Spleen)': '-0.148', 'Platelets': '-0.096', 'Erythrocytes': '-0.161', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.510', 'NK-cells (Spleen)': '0.352', 'Amygdala excitatory': '65.7', 'Cerebellar inhibitory': '104.3', 'Cge interneuron': '102.2', 'Deep-layer corticothalamic and 6b': '72.9', 'Deep-layer intratelencephalic': '67.6', 'Deep-layer near-projecting': '100.7', 'Eccentric medium spiny neuron': '82.3', 'Hippocampal ca1-3': '67.4', 'Hippocampal ca4': '64.7', 'Hippocampal dentate gyrus': '60.6', 'Lamp5-lhx6 and chandelier': '94.5', 'Lower rhombic lip': '126.7', 'Mammillary body': '152.1', 'Medium spiny neuron': '88.2', 'Mge interneuron': '109.3', 'Midbrain-derived inhibitory': '122.3', 'Miscellaneous': '74.6', 'Splatter': '113.4', 'Thalamic excitatory': '91.1', 'Upper rhombic lip': '100.3', 'Upper-layer intratelencephalic': '60.9', 'Astrocyte': '137.8', 'Bergmann glia': '118.5', 'Central nervous system macrophage': '159.7', 'Choroid plexus epithelial cell': '351.6', 'Committed oligodendrocyte precursor': '140.7', 'Ependymal cell': '134.7', 'Oligodendrocyte': '253.6', 'Oligodendrocyte precursor cell': '140.9', 'Endothelial cell': '174.7', 'Pericyte': '127.3', 'Vascular associated smooth muscle cell': '120.8', 'Fibroblast': '175.3', 'Leukocyte': '244.9', 'Basophil': '51.3', 'Eosinophil': '31.9', 'Neutrophil': '19.9', 'Classical monocyte': '37.7', 'Non-classical monocyte': '54.1', 'Intermediate monocyte': '29.2', 'T-reg': '61.8', 'GdT-cell': '42.3', 'MAIT T-cell': '47.3', 'Memory CD4 T-cell': '51.9', 'Naive CD4 T-cell': '184.4', 'Memory CD8 T-cell': '53.3', 'Naive CD8 T-cell': '236.6', 'Memory B-cell': '25.0', 'Naive B-cell': '70.9', 'Plasmacytoid DC': '33.0', 'Myeloid DC': '39.6', 'NK-cell': '126.0', 'Total PBMC': '63.1', 'Vd2 gdTCR': '43.4', 'Memory CD4 T-cell Th1\\/Th17': '150.3', 'Memory CD4 T-cell Th17': '175.6', 'Memory CD4 T-cell Th2': '188.1', 'Non-Vd2 gdTCR': '53.5', 'Memory CD4 T-cell Th1': '174.1', 'Memory CD4 T-cell TFH': '219.6', 'Terminal effector memory CD4 T-cell': '2.5', 'Central memory CD8 T-cell': '63.1', 'Effector memory CD8 T-cell': '60.4', 'Terminal effector memory CD8 T-cell': '41.4', 'Non-switched memory B-cell': '28.2', 'Plasmablast': '66.9', 'Switched memory B-cell': '36.7', 'Exhausted memory B-cell': '34.8', 'Progenitor cell': '49.4', 'Memory T-reg': '212.3', 'Naive CD4 T-cell activated': '130.6', 'Naive CD8 T-cell activated': '158.5', 'Naive T-reg': '196.0'}
null
{'Adipose Tissue': 52.7784634551495, 'Adrenal Gland': 45.411899224806206, 'Bladder': 91.27619047619048, 'Blood': 45.873624327233586, 'Blood Vessel': 72.88290636704119, 'Brain': 80.2245117335352, 'Breast': 61.42228758169935, 'Cervix Uteri': 84.61, 'Colon': 70.77596919127086, 'Esophagus': 88.34064359861591, 'Fallopian Tube': 75.75333333333333, 'Heart': 56.42043089430894, 'Kidney': 52.70168539325842, 'Liver': 30.383898230088494, 'Lung': 69.48072664359862, 'Muscle': 79.71046077210461, 'Nerve': 97.87770597738287, 'Ovary': 77.21627777777778, 'Pancreas': 21.168475609756097, 'Pituitary': 93.99028268551235, 'Prostate': 83.0697142857143, 'Salivary Gland': 78.76654320987655, 'Skin': 69.034090657822, 'Small Intestine': 73.1924064171123, 'Spleen': 83.20917012448133, 'Stomach': 57.87094707520892, 'Testis': 150.8000831024931, 'Thyroid': 81.8859571209801, 'Uterus': 84.55950704225353, 'Vagina': 80.47692307692307}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
80.46528
0.514213
2,008
O60260
Q99962
20064468
UbiNet, UbiBrowser
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
SH3GL2
MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPKPSGVQMDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPINYVEILVALPH
Homo sapiens
Cytoplasm, Membrane, Early endosome, Presynapse
Group enriched (brain, retina)
{'Ciliated cells': '0.3', 'Basal respiratory cells': '0.0', 'Club cells': '0.3', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.0', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '3.5', 'Proximal enterocytes': '0.0', 'Paneth cells': '1.2', 'Distal enterocytes': '0.1', 'Intestinal goblet cells': '0.3', 'Exocrine glandular cells': '-0.195', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.4', 'Breast glandular cells': '0.130', 'Breast myoepithelial cells': '0.237', 'Glandular and luminal cells': '0.1', 'Secretory cells': '0.3', 'Basal keratinocytes': '0.1', 'Suprabasal keratinocytes': '0.0', 'Basal squamous epithelial cells': '0.2', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.633', 'Alveolar cells type 2': '0.143', 'Salivary duct cells': '0.0', 'Ductal cells': '0.313', 'Hepatocytes': '0.061', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.739', 'Distal tubular cells': '0.0', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.742', 'Sertoli cells': '0.214', 'Granulosa cells': '4.3', 'Enteroendocrine cells': '2.6', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '0.131', 'Excitatory neurons': '377.5', 'Inhibitory neurons': '135.4', 'Cone photoreceptor cells': '62.9', 'Rod photoreceptor cells': '20.7', 'Bipolar cells': '74.0', 'Horizontal cells': '29.0', 'Astrocytes': '15.5', 'Oligodendrocyte precursor cells': '39.1', 'Oligodendrocytes': '9.5', 'Microglial cells': '12.5', 'Muller glia cells': '8.2', 'Schwann cells': '0.289', 'Spermatogonia': '0.461', 'Spermatocytes': '0.227', 'Early spermatids': '0.062', 'Late spermatids': '-0.017', 'Oocytes': '99.3', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.1', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '0.1', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '0.580', 'Skeletal myocytes': '0.081', 'Smooth muscle cells': '0.4', 'Adipocytes': '0.0', 'Melanocytes': '0.070', 'Fibroblasts': '0.2', 'Peritubular cells': '0.128', 'Endometrial stromal cells': '0.1', 'Ovarian stromal cells': '0.3', 'Undifferentiated cells': '1.1', 'T-cells': '0.0', 'B-cells': '0.0', 'Plasma cells': '0.0', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.1', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.034', 'Erythroid cells': '-0.007', 'Adipocytes (Subcutaneous)': '0.054', 'Adipocytes (Visceral)': '-0.172', 'Breast glandular cells (progenitors)': '0.148', 'Adipocytes (Breast)': '-0.182', 'Colon enterocytes': '0.083', 'Colon enteroendocrine cells': '0.753', 'Enteric glia cells': '0.349', 'Mitotic cells (Colon)': '0.035', 'Mitotic cells (Heart)': '0.318', 'Podocytes': '0.360', 'Ascending Loop of Henle cells': '-0.099', 'Intercalated cells': '0.278', 'Cholangiocyte': '0.235', 'NK-cells (Liver)': '0.118', 'Respiratory ciliated cells': '-0.026', 'Mitotic cells (Lung)': '-0.084', 'NK-cells (Lung)': '0.193', 'B-cells (Lung)': '-0.099', 'Alpha cells': '0.680', 'Beta cells': '0.723', 'Prostate glandular cells': '0.608', 'Prostate basal glandular cells': '0.262', 'Urothelial cells': '0.001', 'Keratinocyte (other)': '-0.010', 'Keratinocyte (granular)': '-0.234', 'Hair cortex cells': '0.135', 'Inner root sheath cells': '0.209', 'Outer root sheath cells': '0.301', 'Sebaceous gland cells': '0.110', 'Eccrine sweat gland cells': '0.156', 'Adipocytes (Skin)': '0.016', 'Mitotic cells (Skin)': '0.239', 'Parietal cells': '0.859', 'Chief cells': '0.678', 'Gastric mucous cells': '0.516', 'Gastric enteroendocrine cells': '0.565', 'Mitotic cells (Stomach)': '0.053', 'Parafollicular cells': '0.025', 'Thyroid glandular cells': '0.249', 'Mitotic cells (Thyroid)': '0.015', 'Adrenal cortex cells': '0.115', 'Adrenal medulla cells': '0.161', 'Mitotic cells (Adrenal gland)': '0.045', 'Minor salivary glandular cells': '0.064', 'Minor salivary gland ductal cells': '0.181', 'Minor salivary gland basal cells': '-0.046', 'Mitotic cells (Minor salivary gland)': '-0.044', 'Adipocytes (Minor salivary gland)': '0.097', 'Somatotropes': '0.028', 'Lactotropes': '0.410', 'Gonadotropes': '0.080', 'Corticotropes': '0.597', 'Thyrotropes': '0.388', 'Undifferentiated cells (Pituitary gland)': '-0.270', 'Mitotic cells (Spleen)': '-0.048', 'Platelets': '0.025', 'Erythrocytes': '0.001', 'Hematopoietic stem cells': '-0.006', 'B-cells (Spleen)': '-0.021', 'NK-cells (Spleen)': '0.041', 'Amygdala excitatory': '509.1', 'Cerebellar inhibitory': '479.4', 'Cge interneuron': '84.3', 'Deep-layer corticothalamic and 6b': '698.8', 'Deep-layer intratelencephalic': '679.8', 'Deep-layer near-projecting': '460.4', 'Eccentric medium spiny neuron': '172.6', 'Hippocampal ca1-3': '420.2', 'Hippocampal ca4': '800.5', 'Hippocampal dentate gyrus': '378.3', 'Lamp5-lhx6 and chandelier': '148.2', 'Lower rhombic lip': '191.0', 'Mammillary body': '303.8', 'Medium spiny neuron': '339.0', 'Mge interneuron': '215.6', 'Midbrain-derived inhibitory': '512.3', 'Miscellaneous': '438.8', 'Splatter': '185.2', 'Thalamic excitatory': '412.2', 'Upper rhombic lip': '1082.7', 'Upper-layer intratelencephalic': '540.4', 'Astrocyte': '217.1', 'Bergmann glia': '159.1', 'Central nervous system macrophage': '8.3', 'Choroid plexus epithelial cell': '6.6', 'Committed oligodendrocyte precursor': '61.9', 'Ependymal cell': '112.4', 'Oligodendrocyte': '8.1', 'Oligodendrocyte precursor cell': '87.1', 'Endothelial cell': '9.6', 'Pericyte': '8.1', 'Vascular associated smooth muscle cell': '9.8', 'Fibroblast': '8.4', 'Leukocyte': '8.2', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
1X03, 1X04, 2D4C, 2DBM
{'Adipose Tissue': 0.480329011627907, 'Adrenal Gland': 0.3492488604651163, 'Bladder': 9.626438095238097, 'Blood': 0.0720255532831001, 'Blood Vessel': 0.1712879700374532, 'Brain': 132.61905272520818, 'Breast': 0.2746201742919389, 'Cervix Uteri': 0.734147894736842, 'Colon': 0.6882364441591784, 'Esophagus': 3.613718823529412, 'Fallopian Tube': 4.814222222222223, 'Heart': 1.2256292961672477, 'Kidney': 8.232696629213484, 'Liver': 0.1582600884955752, 'Lung': 2.3533363321799308, 'Muscle': 0.1036045180572851, 'Nerve': 0.3586007754442649, 'Ovary': 2.271167222222222, 'Pancreas': 0.9817181097560976, 'Pituitary': 50.02163992932862, 'Prostate': 3.087874244897959, 'Salivary Gland': 0.154065, 'Skin': 0.1565848109452736, 'Small Intestine': 0.6468177540106952, 'Spleen': 0.1589844813278008, 'Stomach': 10.068485793871869, 'Testis': 12.906041551246538, 'Thyroid': 2.0965076110260337, 'Uterus': 3.277943098591549, 'Vagina': 0.8984918589743589}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
85.623352
0.452358
2,162
O60260
Q99963
20064468
UbiNet, UbiBrowser
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
SH3GL3
MSVAGLKKQFHKASQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILSKTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGNALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEILQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ
Homo sapiens
Cytoplasm, Early endosome membrane
Tissue enhanced (brain, testis)
{'Ciliated cells': '3.9', 'Basal respiratory cells': '0.4', 'Club cells': '0.4', 'Ionocytes': '0.4', 'Mucus glandular cells': '0.3', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.241', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.450', 'Breast myoepithelial cells': '0.418', 'Glandular and luminal cells': '0.1', 'Secretory cells': '0.1', 'Basal keratinocytes': '8.0', 'Suprabasal keratinocytes': '45.1', 'Basal squamous epithelial cells': '14.8', 'Squamous epithelial cells': '7.9', 'Alveolar cells type 1': '0.668', 'Alveolar cells type 2': '-0.017', 'Salivary duct cells': '0.7', 'Ductal cells': '0.455', 'Hepatocytes': '-0.074', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.139', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.756', 'Sertoli cells': '-0.602', 'Granulosa cells': '0.8', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '-0.605', 'Excitatory neurons': '185.9', 'Inhibitory neurons': '214.9', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.4', 'Bipolar cells': '8.0', 'Horizontal cells': '19.5', 'Astrocytes': '5.6', 'Oligodendrocyte precursor cells': '27.4', 'Oligodendrocytes': '1063.6', 'Microglial cells': '6.3', 'Muller glia cells': '3.2', 'Schwann cells': '0.486', 'Spermatogonia': '-0.347', 'Spermatocytes': '0.041', 'Early spermatids': '0.707', 'Late spermatids': '0.816', 'Oocytes': '54.4', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '1.2', 'Endothelial cells': '0.5', 'Lymphatic endothelial cells': '0.1', 'Cardiomyocytes': '0.059', 'Skeletal myocytes': '0.045', 'Smooth muscle cells': '1.3', 'Adipocytes': '0.1', 'Melanocytes': '0.076', 'Fibroblasts': '1.1', 'Peritubular cells': '-0.440', 'Endometrial stromal cells': '0.1', 'Ovarian stromal cells': '0.5', 'Undifferentiated cells': '0.1', 'T-cells': '0.1', 'B-cells': '0.0', 'Plasma cells': '0.0', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.5', 'Hofbauer cells': '0.3', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '-0.193', 'Erythroid cells': '0.063', 'Adipocytes (Subcutaneous)': '-0.123', 'Adipocytes (Visceral)': '-0.315', 'Breast glandular cells (progenitors)': '0.328', 'Adipocytes (Breast)': '-0.320', 'Colon enterocytes': '-0.085', 'Colon enteroendocrine cells': '0.453', 'Enteric glia cells': '0.301', 'Mitotic cells (Colon)': '-0.179', 'Mitotic cells (Heart)': '0.112', 'Podocytes': '-0.200', 'Ascending Loop of Henle cells': '0.571', 'Intercalated cells': '-0.013', 'Cholangiocyte': '0.139', 'NK-cells (Liver)': '0.089', 'Respiratory ciliated cells': '0.145', 'Mitotic cells (Lung)': '-0.161', 'NK-cells (Lung)': '0.366', 'B-cells (Lung)': '0.011', 'Alpha cells': '0.198', 'Beta cells': '0.106', 'Prostate glandular cells': '-0.035', 'Prostate basal glandular cells': '0.192', 'Urothelial cells': '0.258', 'Keratinocyte (other)': '-0.392', 'Keratinocyte (granular)': '-0.106', 'Hair cortex cells': '0.563', 'Inner root sheath cells': '0.681', 'Outer root sheath cells': '0.473', 'Sebaceous gland cells': '0.125', 'Eccrine sweat gland cells': '0.243', 'Adipocytes (Skin)': '0.269', 'Mitotic cells (Skin)': '0.136', 'Parietal cells': '-0.598', 'Chief cells': '-0.506', 'Gastric mucous cells': '-0.493', 'Gastric enteroendocrine cells': '-0.348', 'Mitotic cells (Stomach)': '-0.225', 'Parafollicular cells': '0.127', 'Thyroid glandular cells': '0.087', 'Mitotic cells (Thyroid)': '0.092', 'Adrenal cortex cells': '0.016', 'Adrenal medulla cells': '0.563', 'Mitotic cells (Adrenal gland)': '0.090', 'Minor salivary glandular cells': '-0.296', 'Minor salivary gland ductal cells': '-0.144', 'Minor salivary gland basal cells': '0.651', 'Mitotic cells (Minor salivary gland)': '0.424', 'Adipocytes (Minor salivary gland)': '0.101', 'Somatotropes': '0.430', 'Lactotropes': '0.211', 'Gonadotropes': '0.283', 'Corticotropes': '-0.211', 'Thyrotropes': '-0.092', 'Undifferentiated cells (Pituitary gland)': '-0.100', 'Mitotic cells (Spleen)': '-0.093', 'Platelets': '0.001', 'Erythrocytes': '0.007', 'Hematopoietic stem cells': '0.038', 'B-cells (Spleen)': '0.008', 'NK-cells (Spleen)': '0.030', 'Amygdala excitatory': '334.5', 'Cerebellar inhibitory': '196.5', 'Cge interneuron': '397.7', 'Deep-layer corticothalamic and 6b': '482.0', 'Deep-layer intratelencephalic': '440.8', 'Deep-layer near-projecting': '456.2', 'Eccentric medium spiny neuron': '364.5', 'Hippocampal ca1-3': '341.2', 'Hippocampal ca4': '352.1', 'Hippocampal dentate gyrus': '464.7', 'Lamp5-lhx6 and chandelier': '364.3', 'Lower rhombic lip': '269.0', 'Mammillary body': '84.5', 'Medium spiny neuron': '347.2', 'Mge interneuron': '275.5', 'Midbrain-derived inhibitory': '326.1', 'Miscellaneous': '315.1', 'Splatter': '229.3', 'Thalamic excitatory': '132.0', 'Upper rhombic lip': '235.9', 'Upper-layer intratelencephalic': '392.1', 'Astrocyte': '11.8', 'Bergmann glia': '3.5', 'Central nervous system macrophage': '13.0', 'Choroid plexus epithelial cell': '167.7', 'Committed oligodendrocyte precursor': '553.5', 'Ependymal cell': '183.9', 'Oligodendrocyte': '1662.2', 'Oligodendrocyte precursor cell': '67.2', 'Endothelial cell': '12.0', 'Pericyte': '9.3', 'Vascular associated smooth muscle cell': '16.8', 'Fibroblast': '8.8', 'Leukocyte': '13.9', 'Basophil': '0.2', 'Eosinophil': '0.0', 'Neutrophil': '0.3', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.1', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.2', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.1', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.1', 'Effector memory CD8 T-cell': '0.1', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.1', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.3', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
2EW3, 2Z0V
{'Adipose Tissue': 0.2212405664451827, 'Adrenal Gland': 0.1020378372093023, 'Bladder': 1.7969666666666666, 'Blood': 0.0395234951560818, 'Blood Vessel': 0.4957110861423221, 'Brain': 39.92886979560939, 'Breast': 0.2047844836601307, 'Cervix Uteri': 1.5186684210526316, 'Colon': 0.362196785622593, 'Esophagus': 1.3495648512110727, 'Fallopian Tube': 0.87569, 'Heart': 0.2245650801393728, 'Kidney': 1.1552407415730337, 'Liver': 0.0262535707964601, 'Lung': 2.1297132871972315, 'Muscle': 0.0408815641344956, 'Nerve': 0.6078683683360258, 'Ovary': 0.3706507777777778, 'Pancreas': 0.0950029329268292, 'Pituitary': 2.4288360424028266, 'Prostate': 0.6825204081632653, 'Salivary Gland': 1.4633152469135804, 'Skin': 0.5016626987285794, 'Small Intestine': 0.1340258288770053, 'Spleen': 0.0310181908713692, 'Stomach': 0.2156579944289693, 'Testis': 101.60631301939058, 'Thyroid': 0.0991177059724349, 'Uterus': 0.6304914084507043, 'Vagina': 1.5139772435897436}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
88.178818
0.440749
2,162
O60260
Q9BRX8
33082525
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
PRXL2A
MSFLQDPSFFTMGMWSIGAGALGAAALALLLANTDVFLSKPQKAALEYLEDIDLKTLEKEPRTFKAKELWEKNGAVIMAVRRPGCFLCREEAADLSSLKSMLDQLGVPLYAVVKEHIRTEVKDFQPYFKGEIFLDEKKKFYGPQRRKMMFMGFIRLGVWYNFFRAWNGGFSGNLEGEGFILGGVFVVGSGKQGILLEHREKEFGDKVNLLSVLEAAKMIKPQTLASEKK
Homo sapiens
Cytoplasm, Secreted
Tissue enhanced (adipose)
{'Ciliated cells': '86.9', 'Basal respiratory cells': '150.6', 'Club cells': '101.3', 'Ionocytes': '88.4', 'Mucus glandular cells': '44.0', 'Serous glandular cells': '108.3', 'Gastric mucus-secreting cells': '8.3', 'Proximal enterocytes': '278.4', 'Paneth cells': '78.1', 'Distal enterocytes': '128.0', 'Intestinal goblet cells': '59.6', 'Exocrine glandular cells': '-0.149', 'Basal prostatic cells': '49.8', 'Prostatic glandular cells': '200.0', 'Breast glandular cells': '-0.481', 'Breast myoepithelial cells': '-0.618', 'Glandular and luminal cells': '324.9', 'Secretory cells': '56.0', 'Basal keratinocytes': '245.8', 'Suprabasal keratinocytes': '203.8', 'Basal squamous epithelial cells': '69.8', 'Squamous epithelial cells': '99.8', 'Alveolar cells type 1': '-0.125', 'Alveolar cells type 2': '0.293', 'Salivary duct cells': '108.7', 'Ductal cells': '0.418', 'Hepatocytes': '0.738', 'Cholangiocytes': '78.2', 'Proximal tubular cells': '0.129', 'Distal tubular cells': '113.7', 'Collecting duct cells': '99.2', 'Mesothelial cells': '-0.325', 'Sertoli cells': '0.719', 'Granulosa cells': '162.4', 'Enteroendocrine cells': '123.7', 'Pancreatic endocrine cells': '52.6', 'Leydig cells': '0.651', 'Excitatory neurons': '36.5', 'Inhibitory neurons': '17.8', 'Cone photoreceptor cells': '389.1', 'Rod photoreceptor cells': '23.0', 'Bipolar cells': '14.2', 'Horizontal cells': '49.1', 'Astrocytes': '43.0', 'Oligodendrocyte precursor cells': '18.9', 'Oligodendrocytes': '12.1', 'Microglial cells': '8.9', 'Muller glia cells': '126.0', 'Schwann cells': '0.212', 'Spermatogonia': '0.584', 'Spermatocytes': '0.229', 'Early spermatids': '-0.393', 'Late spermatids': '-0.712', 'Oocytes': '91.9', 'Cytotrophoblasts': '14.2', 'Syncytiotrophoblasts': '2.6', 'Extravillous trophoblasts': '6.2', 'Endothelial cells': '107.2', 'Lymphatic endothelial cells': '136.4', 'Cardiomyocytes': '0.712', 'Skeletal myocytes': '-0.077', 'Smooth muscle cells': '106.8', 'Adipocytes': '301.7', 'Melanocytes': '0.200', 'Fibroblasts': '41.1', 'Peritubular cells': '0.536', 'Endometrial stromal cells': '196.8', 'Ovarian stromal cells': '48.9', 'Undifferentiated cells': '88.8', 'T-cells': '11.0', 'B-cells': '17.5', 'Plasma cells': '12.8', 'Nk-cells': '3.6', 'Granulocytes': '56.5', 'Monocytes': '0.4', 'Macrophages': '32.5', 'Hofbauer cells': '64.0', 'Kupffer cells': '60.0', 'Dendritic cells': '83.5', 'Langerhans cells': '0.356', 'Erythroid cells': '0.058', 'Adipocytes (Subcutaneous)': '0.811', 'Adipocytes (Visceral)': '0.803', 'Breast glandular cells (progenitors)': '-0.456', 'Adipocytes (Breast)': '0.916', 'Colon enterocytes': '-0.093', 'Colon enteroendocrine cells': '0.347', 'Enteric glia cells': '-0.047', 'Mitotic cells (Colon)': '-0.118', 'Mitotic cells (Heart)': '0.347', 'Podocytes': '-0.085', 'Ascending Loop of Henle cells': '0.531', 'Intercalated cells': '0.015', 'Cholangiocyte': '-0.053', 'NK-cells (Liver)': '0.185', 'Respiratory ciliated cells': '0.041', 'Mitotic cells (Lung)': '0.185', 'NK-cells (Lung)': '-0.410', 'B-cells (Lung)': '-0.212', 'Alpha cells': '0.378', 'Beta cells': '0.232', 'Prostate glandular cells': '0.351', 'Prostate basal glandular cells': '0.258', 'Urothelial cells': '0.037', 'Keratinocyte (other)': '0.272', 'Keratinocyte (granular)': '0.144', 'Hair cortex cells': '-0.160', 'Inner root sheath cells': '-0.133', 'Outer root sheath cells': '-0.048', 'Sebaceous gland cells': '0.555', 'Eccrine sweat gland cells': '-0.215', 'Adipocytes (Skin)': '-0.010', 'Mitotic cells (Skin)': '0.296', 'Parietal cells': '-0.667', 'Chief cells': '-0.477', 'Gastric mucous cells': '-0.561', 'Gastric enteroendocrine cells': '-0.412', 'Mitotic cells (Stomach)': '-0.129', 'Parafollicular cells': '0.083', 'Thyroid glandular cells': '0.394', 'Mitotic cells (Thyroid)': '-0.078', 'Adrenal cortex cells': '0.381', 'Adrenal medulla cells': '0.156', 'Mitotic cells (Adrenal gland)': '0.319', 'Minor salivary glandular cells': '-0.042', 'Minor salivary gland ductal cells': '-0.115', 'Minor salivary gland basal cells': '0.618', 'Mitotic cells (Minor salivary gland)': '0.595', 'Adipocytes (Minor salivary gland)': '0.428', 'Somatotropes': '0.264', 'Lactotropes': '0.029', 'Gonadotropes': '-0.084', 'Corticotropes': '0.192', 'Thyrotropes': '0.126', 'Undifferentiated cells (Pituitary gland)': '0.068', 'Mitotic cells (Spleen)': '-0.236', 'Platelets': '-0.123', 'Erythrocytes': '-0.286', 'Hematopoietic stem cells': '-0.232', 'B-cells (Spleen)': '0.193', 'NK-cells (Spleen)': '0.161', 'Amygdala excitatory': '42.8', 'Cerebellar inhibitory': '33.3', 'Cge interneuron': '51.6', 'Deep-layer corticothalamic and 6b': '46.5', 'Deep-layer intratelencephalic': '52.0', 'Deep-layer near-projecting': '44.3', 'Eccentric medium spiny neuron': '50.3', 'Hippocampal ca1-3': '46.4', 'Hippocampal ca4': '75.5', 'Hippocampal dentate gyrus': '10.5', 'Lamp5-lhx6 and chandelier': '104.4', 'Lower rhombic lip': '61.0', 'Mammillary body': '27.9', 'Medium spiny neuron': '48.6', 'Mge interneuron': '45.9', 'Midbrain-derived inhibitory': '51.9', 'Miscellaneous': '44.0', 'Splatter': '45.1', 'Thalamic excitatory': '75.8', 'Upper rhombic lip': '9.8', 'Upper-layer intratelencephalic': '57.2', 'Astrocyte': '104.7', 'Bergmann glia': '69.4', 'Central nervous system macrophage': '24.4', 'Choroid plexus epithelial cell': '60.2', 'Committed oligodendrocyte precursor': '34.9', 'Ependymal cell': '55.8', 'Oligodendrocyte': '23.4', 'Oligodendrocyte precursor cell': '39.6', 'Endothelial cell': '81.4', 'Pericyte': '111.4', 'Vascular associated smooth muscle cell': '37.1', 'Fibroblast': '36.5', 'Leukocyte': '10.3', 'Basophil': '2.8', 'Eosinophil': '11.7', 'Neutrophil': '3.6', 'Classical monocyte': '2.0', 'Non-classical monocyte': '0.3', 'Intermediate monocyte': '3.2', 'T-reg': '9.7', 'GdT-cell': '6.6', 'MAIT T-cell': '12.7', 'Memory CD4 T-cell': '3.7', 'Naive CD4 T-cell': '11.9', 'Memory CD8 T-cell': '5.5', 'Naive CD8 T-cell': '10.6', 'Memory B-cell': '15.8', 'Naive B-cell': '5.9', 'Plasmacytoid DC': '168.4', 'Myeloid DC': '6.6', 'NK-cell': '2.5', 'Total PBMC': '9.1', 'Vd2 gdTCR': '13.6', 'Memory CD4 T-cell Th1\\/Th17': '2.5', 'Memory CD4 T-cell Th17': '2.1', 'Memory CD4 T-cell Th2': '2.8', 'Non-Vd2 gdTCR': '6.4', 'Memory CD4 T-cell Th1': '3.0', 'Memory CD4 T-cell TFH': '3.8', 'Terminal effector memory CD4 T-cell': '8.0', 'Central memory CD8 T-cell': '8.5', 'Effector memory CD8 T-cell': '6.6', 'Terminal effector memory CD8 T-cell': '5.9', 'Non-switched memory B-cell': '21.2', 'Plasmablast': '3.0', 'Switched memory B-cell': '9.4', 'Exhausted memory B-cell': '14.9', 'Progenitor cell': '32.2', 'Memory T-reg': '1.0', 'Naive CD4 T-cell activated': '3.6', 'Naive CD8 T-cell activated': '4.2', 'Naive T-reg': '8.7'}
null
{}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
88.353188
0.356201
2,629
O60260
Q9BT88
12925569, UNIPROT
UbiNet, UbiBrowser, 31181401
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
SYT11
MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLKGISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSEY
Homo sapiens
Cytoplasmic vesicle membrane, Perikaryon, Golgi apparatus, trans-Golgi network membrane, Recycling endosome membrane, Lysosome membrane, Cytoplasmic vesicle, phagosome, Cell projection, axon, Cell projection, dendrite, Postsynaptic density, Recycling endosome membrane, Cytoplasmic vesicle, clathrin-coated vesicle membrane, Perikaryon
Group enriched (brain, retina)
{'Ciliated cells': '0.6', 'Basal respiratory cells': '0.1', 'Club cells': '0.5', 'Ionocytes': '0.0', 'Mucus glandular cells': '1.7', 'Serous glandular cells': '0.8', 'Gastric mucus-secreting cells': '1.2', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.530', 'Basal prostatic cells': '1.2', 'Prostatic glandular cells': '0.4', 'Breast glandular cells': '0.001', 'Breast myoepithelial cells': '0.018', 'Glandular and luminal cells': '1.6', 'Secretory cells': '0.3', 'Basal keratinocytes': '0.7', 'Suprabasal keratinocytes': '0.2', 'Basal squamous epithelial cells': '0.7', 'Squamous epithelial cells': '0.2', 'Alveolar cells type 1': '0.077', 'Alveolar cells type 2': '-0.451', 'Salivary duct cells': '0.5', 'Ductal cells': '0.623', 'Hepatocytes': '0.130', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.011', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.076', 'Sertoli cells': '0.692', 'Granulosa cells': '6.9', 'Enteroendocrine cells': '4.0', 'Pancreatic endocrine cells': '13.6', 'Leydig cells': '0.650', 'Excitatory neurons': '80.7', 'Inhibitory neurons': '99.9', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '10.8', 'Bipolar cells': '69.2', 'Horizontal cells': '90.6', 'Astrocytes': '86.4', 'Oligodendrocyte precursor cells': '106.1', 'Oligodendrocytes': '124.0', 'Microglial cells': '22.4', 'Muller glia cells': '126.5', 'Schwann cells': '0.476', 'Spermatogonia': '0.524', 'Spermatocytes': '0.151', 'Early spermatids': '-0.485', 'Late spermatids': '-0.607', 'Oocytes': '2.2', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '17.5', 'Lymphatic endothelial cells': '12.1', 'Cardiomyocytes': '0.435', 'Skeletal myocytes': '-0.008', 'Smooth muscle cells': '17.9', 'Adipocytes': '24.2', 'Melanocytes': '-0.037', 'Fibroblasts': '11.2', 'Peritubular cells': '0.358', 'Endometrial stromal cells': '11.2', 'Ovarian stromal cells': '10.6', 'Undifferentiated cells': '0.0', 'T-cells': '15.8', 'B-cells': '2.8', 'Plasma cells': '0.9', 'Nk-cells': '29.8', 'Granulocytes': '12.3', 'Monocytes': '9.8', 'Macrophages': '12.3', 'Hofbauer cells': '6.3', 'Kupffer cells': '7.6', 'Dendritic cells': '0.8', 'Langerhans cells': '0.026', 'Erythroid cells': '0.080', 'Adipocytes (Subcutaneous)': '-0.518', 'Adipocytes (Visceral)': '-0.394', 'Breast glandular cells (progenitors)': '-0.116', 'Adipocytes (Breast)': '0.000', 'Colon enterocytes': '-0.140', 'Colon enteroendocrine cells': '0.632', 'Enteric glia cells': '0.721', 'Mitotic cells (Colon)': '-0.106', 'Mitotic cells (Heart)': '0.554', 'Podocytes': '-0.072', 'Ascending Loop of Henle cells': '0.519', 'Intercalated cells': '-0.067', 'Cholangiocyte': '0.488', 'NK-cells (Liver)': '-0.005', 'Respiratory ciliated cells': '0.084', 'Mitotic cells (Lung)': '-0.038', 'NK-cells (Lung)': '0.294', 'B-cells (Lung)': '0.082', 'Alpha cells': '0.593', 'Beta cells': '0.434', 'Prostate glandular cells': '-0.602', 'Prostate basal glandular cells': '-0.339', 'Urothelial cells': '-0.147', 'Keratinocyte (other)': '-0.446', 'Keratinocyte (granular)': '-0.191', 'Hair cortex cells': '0.356', 'Inner root sheath cells': '0.311', 'Outer root sheath cells': '0.385', 'Sebaceous gland cells': '0.155', 'Eccrine sweat gland cells': '0.458', 'Adipocytes (Skin)': '0.454', 'Mitotic cells (Skin)': '0.054', 'Parietal cells': '-0.753', 'Chief cells': '-0.630', 'Gastric mucous cells': '-0.626', 'Gastric enteroendocrine cells': '-0.433', 'Mitotic cells (Stomach)': '-0.206', 'Parafollicular cells': '0.015', 'Thyroid glandular cells': '-0.019', 'Mitotic cells (Thyroid)': '0.260', 'Adrenal cortex cells': '0.390', 'Adrenal medulla cells': '0.517', 'Mitotic cells (Adrenal gland)': '0.427', 'Minor salivary glandular cells': '0.301', 'Minor salivary gland ductal cells': '0.135', 'Minor salivary gland basal cells': '0.223', 'Mitotic cells (Minor salivary gland)': '0.322', 'Adipocytes (Minor salivary gland)': '0.278', 'Somatotropes': '-0.054', 'Lactotropes': '-0.004', 'Gonadotropes': '0.008', 'Corticotropes': '-0.143', 'Thyrotropes': '0.034', 'Undifferentiated cells (Pituitary gland)': '0.319', 'Mitotic cells (Spleen)': '-0.283', 'Platelets': '-0.075', 'Erythrocytes': '-0.124', 'Hematopoietic stem cells': '-0.184', 'B-cells (Spleen)': '0.065', 'NK-cells (Spleen)': '0.312', 'Amygdala excitatory': '130.3', 'Cerebellar inhibitory': '111.7', 'Cge interneuron': '213.2', 'Deep-layer corticothalamic and 6b': '148.1', 'Deep-layer intratelencephalic': '135.0', 'Deep-layer near-projecting': '126.5', 'Eccentric medium spiny neuron': '166.7', 'Hippocampal ca1-3': '116.8', 'Hippocampal ca4': '108.3', 'Hippocampal dentate gyrus': '84.8', 'Lamp5-lhx6 and chandelier': '175.8', 'Lower rhombic lip': '82.8', 'Mammillary body': '149.4', 'Medium spiny neuron': '130.0', 'Mge interneuron': '158.9', 'Midbrain-derived inhibitory': '163.9', 'Miscellaneous': '123.9', 'Splatter': '132.7', 'Thalamic excitatory': '145.9', 'Upper rhombic lip': '129.0', 'Upper-layer intratelencephalic': '109.9', 'Astrocyte': '181.2', 'Bergmann glia': '157.0', 'Central nervous system macrophage': '30.1', 'Choroid plexus epithelial cell': '25.1', 'Committed oligodendrocyte precursor': '210.6', 'Ependymal cell': '115.3', 'Oligodendrocyte': '246.0', 'Oligodendrocyte precursor cell': '235.7', 'Endothelial cell': '51.0', 'Pericyte': '59.6', 'Vascular associated smooth muscle cell': '54.7', 'Fibroblast': '23.1', 'Leukocyte': '26.1', 'Basophil': '18.7', 'Eosinophil': '0.1', 'Neutrophil': '7.8', 'Classical monocyte': '14.5', 'Non-classical monocyte': '21.2', 'Intermediate monocyte': '22.4', 'T-reg': '19.1', 'GdT-cell': '16.9', 'MAIT T-cell': '22.0', 'Memory CD4 T-cell': '8.8', 'Naive CD4 T-cell': '1.7', 'Memory CD8 T-cell': '11.7', 'Naive CD8 T-cell': '8.5', 'Memory B-cell': '1.9', 'Naive B-cell': '5.5', 'Plasmacytoid DC': '1.2', 'Myeloid DC': '20.3', 'NK-cell': '90.3', 'Total PBMC': '23.5', 'Vd2 gdTCR': '41.1', 'Memory CD4 T-cell Th1\\/Th17': '15.7', 'Memory CD4 T-cell Th17': '42.5', 'Memory CD4 T-cell Th2': '38.1', 'Non-Vd2 gdTCR': '75.5', 'Memory CD4 T-cell Th1': '17.8', 'Memory CD4 T-cell TFH': '31.0', 'Terminal effector memory CD4 T-cell': '66.5', 'Central memory CD8 T-cell': '37.1', 'Effector memory CD8 T-cell': '62.5', 'Terminal effector memory CD8 T-cell': '75.2', 'Non-switched memory B-cell': '6.1', 'Plasmablast': '2.1', 'Switched memory B-cell': '16.4', 'Exhausted memory B-cell': '23.9', 'Progenitor cell': '26.3', 'Memory T-reg': '58.5', 'Naive CD4 T-cell activated': '1.9', 'Naive CD8 T-cell activated': '8.5', 'Naive T-reg': '4.4'}
null
{'Adipose Tissue': 12.706839700996678, 'Adrenal Gland': 7.619097286821706, 'Bladder': 22.72228571428571, 'Blood': 9.90550064585576, 'Blood Vessel': 61.482741573033714, 'Brain': 159.67598410295233, 'Breast': 10.292043572984747, 'Cervix Uteri': 35.549578947368424, 'Colon': 21.900270860077026, 'Esophagus': 14.29095356401384, 'Fallopian Tube': 21.844, 'Heart': 9.670207897793263, 'Kidney': 6.178921348314606, 'Liver': 0.8417778761061947, 'Lung': 17.830422145328722, 'Muscle': 2.0927819427148195, 'Nerve': 77.82680129240711, 'Ovary': 25.75657222222222, 'Pancreas': 1.6698198170731708, 'Pituitary': 79.69049469964665, 'Prostate': 20.07689387755102, 'Salivary Gland': 4.3046395061728395, 'Skin': 10.420101547816474, 'Small Intestine': 13.521582887700536, 'Spleen': 11.379547717842325, 'Stomach': 10.680440111420612, 'Testis': 14.021728531855956, 'Thyroid': 9.030480857580397, 'Uterus': 39.406056338028165, 'Vagina': 22.85152564102564}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
76.020116
0.507726
1,838
O60260
Q9BXK5
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
BCL2L13
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVKTEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYSAEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK
Homo sapiens
Mitochondrion membrane, Nucleus, Nucleus
Tissue enhanced (skeletal)
{'Ciliated cells': '17.5', 'Basal respiratory cells': '21.8', 'Club cells': '19.6', 'Ionocytes': '12.9', 'Mucus glandular cells': '19.6', 'Serous glandular cells': '17.3', 'Gastric mucus-secreting cells': '14.7', 'Proximal enterocytes': '31.9', 'Paneth cells': '15.1', 'Distal enterocytes': '35.1', 'Intestinal goblet cells': '24.0', 'Exocrine glandular cells': '-0.697', 'Basal prostatic cells': '17.1', 'Prostatic glandular cells': '17.4', 'Breast glandular cells': '-0.170', 'Breast myoepithelial cells': '-0.218', 'Glandular and luminal cells': '24.6', 'Secretory cells': '18.3', 'Basal keratinocytes': '25.8', 'Suprabasal keratinocytes': '29.0', 'Basal squamous epithelial cells': '27.5', 'Squamous epithelial cells': '32.6', 'Alveolar cells type 1': '0.295', 'Alveolar cells type 2': '0.183', 'Salivary duct cells': '19.5', 'Ductal cells': '0.537', 'Hepatocytes': '0.528', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.434', 'Distal tubular cells': '36.9', 'Collecting duct cells': '17.5', 'Mesothelial cells': '0.066', 'Sertoli cells': '0.658', 'Granulosa cells': '19.4', 'Enteroendocrine cells': '26.0', 'Pancreatic endocrine cells': '20.4', 'Leydig cells': '0.481', 'Excitatory neurons': '40.5', 'Inhibitory neurons': '36.5', 'Cone photoreceptor cells': '18.7', 'Rod photoreceptor cells': '27.5', 'Bipolar cells': '152.0', 'Horizontal cells': '52.2', 'Astrocytes': '30.7', 'Oligodendrocyte precursor cells': '25.9', 'Oligodendrocytes': '42.3', 'Microglial cells': '25.9', 'Muller glia cells': '50.2', 'Schwann cells': '0.065', 'Spermatogonia': '0.606', 'Spermatocytes': '0.471', 'Early spermatids': '-0.071', 'Late spermatids': '-0.524', 'Oocytes': '23.5', 'Cytotrophoblasts': '49.1', 'Syncytiotrophoblasts': '95.6', 'Extravillous trophoblasts': '33.5', 'Endothelial cells': '15.5', 'Lymphatic endothelial cells': '13.8', 'Cardiomyocytes': '0.677', 'Skeletal myocytes': '-0.351', 'Smooth muscle cells': '15.4', 'Adipocytes': '18.1', 'Melanocytes': '0.257', 'Fibroblasts': '19.2', 'Peritubular cells': '0.348', 'Endometrial stromal cells': '15.8', 'Ovarian stromal cells': '11.0', 'Undifferentiated cells': '26.4', 'T-cells': '17.8', 'B-cells': '19.2', 'Plasma cells': '16.8', 'Nk-cells': '15.9', 'Granulocytes': '24.5', 'Monocytes': '48.6', 'Macrophages': '24.2', 'Hofbauer cells': '29.9', 'Kupffer cells': '24.6', 'Dendritic cells': '44.6', 'Langerhans cells': '0.405', 'Erythroid cells': '-0.097', 'Adipocytes (Subcutaneous)': '0.734', 'Adipocytes (Visceral)': '0.422', 'Breast glandular cells (progenitors)': '-0.101', 'Adipocytes (Breast)': '0.459', 'Colon enterocytes': '-0.153', 'Colon enteroendocrine cells': '0.144', 'Enteric glia cells': '-0.253', 'Mitotic cells (Colon)': '-0.063', 'Mitotic cells (Heart)': '0.418', 'Podocytes': '0.146', 'Ascending Loop of Henle cells': '0.230', 'Intercalated cells': '0.132', 'Cholangiocyte': '0.240', 'NK-cells (Liver)': '-0.246', 'Respiratory ciliated cells': '-0.074', 'Mitotic cells (Lung)': '0.018', 'NK-cells (Lung)': '-0.107', 'B-cells (Lung)': '-0.242', 'Alpha cells': '0.318', 'Beta cells': '0.157', 'Prostate glandular cells': '0.015', 'Prostate basal glandular cells': '0.160', 'Urothelial cells': '0.024', 'Keratinocyte (other)': '0.485', 'Keratinocyte (granular)': '0.302', 'Hair cortex cells': '-0.173', 'Inner root sheath cells': '-0.116', 'Outer root sheath cells': '-0.156', 'Sebaceous gland cells': '0.089', 'Eccrine sweat gland cells': '-0.155', 'Adipocytes (Skin)': '-0.160', 'Mitotic cells (Skin)': '0.356', 'Parietal cells': '-0.533', 'Chief cells': '-0.422', 'Gastric mucous cells': '-0.427', 'Gastric enteroendocrine cells': '-0.412', 'Mitotic cells (Stomach)': '-0.009', 'Parafollicular cells': '0.120', 'Thyroid glandular cells': '0.539', 'Mitotic cells (Thyroid)': '-0.044', 'Adrenal cortex cells': '0.747', 'Adrenal medulla cells': '-0.003', 'Mitotic cells (Adrenal gland)': '0.423', 'Minor salivary glandular cells': '0.284', 'Minor salivary gland ductal cells': '-0.199', 'Minor salivary gland basal cells': '0.488', 'Mitotic cells (Minor salivary gland)': '0.563', 'Adipocytes (Minor salivary gland)': '0.223', 'Somatotropes': '0.172', 'Lactotropes': '0.164', 'Gonadotropes': '-0.064', 'Corticotropes': '-0.136', 'Thyrotropes': '0.035', 'Undifferentiated cells (Pituitary gland)': '0.009', 'Mitotic cells (Spleen)': '-0.229', 'Platelets': '-0.077', 'Erythrocytes': '-0.125', 'Hematopoietic stem cells': '-0.121', 'B-cells (Spleen)': '0.174', 'NK-cells (Spleen)': '0.205', 'Amygdala excitatory': '69.5', 'Cerebellar inhibitory': '60.0', 'Cge interneuron': '57.3', 'Deep-layer corticothalamic and 6b': '62.7', 'Deep-layer intratelencephalic': '77.4', 'Deep-layer near-projecting': '69.8', 'Eccentric medium spiny neuron': '65.7', 'Hippocampal ca1-3': '79.1', 'Hippocampal ca4': '68.5', 'Hippocampal dentate gyrus': '74.6', 'Lamp5-lhx6 and chandelier': '55.3', 'Lower rhombic lip': '83.9', 'Mammillary body': '86.0', 'Medium spiny neuron': '71.9', 'Mge interneuron': '67.6', 'Midbrain-derived inhibitory': '67.1', 'Miscellaneous': '70.6', 'Splatter': '64.0', 'Thalamic excitatory': '76.0', 'Upper rhombic lip': '79.4', 'Upper-layer intratelencephalic': '74.9', 'Astrocyte': '79.0', 'Bergmann glia': '74.0', 'Central nervous system macrophage': '77.8', 'Choroid plexus epithelial cell': '97.7', 'Committed oligodendrocyte precursor': '58.7', 'Ependymal cell': '60.0', 'Oligodendrocyte': '78.9', 'Oligodendrocyte precursor cell': '53.4', 'Endothelial cell': '50.0', 'Pericyte': '61.0', 'Vascular associated smooth muscle cell': '42.5', 'Fibroblast': '85.0', 'Leukocyte': '55.7', 'Basophil': '20.0', 'Eosinophil': '2.3', 'Neutrophil': '13.3', 'Classical monocyte': '32.3', 'Non-classical monocyte': '31.9', 'Intermediate monocyte': '22.9', 'T-reg': '14.8', 'GdT-cell': '2.3', 'MAIT T-cell': '15.2', 'Memory CD4 T-cell': '3.1', 'Naive CD4 T-cell': '33.4', 'Memory CD8 T-cell': '2.7', 'Naive CD8 T-cell': '30.9', 'Memory B-cell': '3.2', 'Naive B-cell': '22.0', 'Plasmacytoid DC': '15.7', 'Myeloid DC': '20.7', 'NK-cell': '26.8', 'Total PBMC': '18.4', 'Vd2 gdTCR': '17.4', 'Memory CD4 T-cell Th1\\/Th17': '27.5', 'Memory CD4 T-cell Th17': '27.8', 'Memory CD4 T-cell Th2': '27.9', 'Non-Vd2 gdTCR': '16.7', 'Memory CD4 T-cell Th1': '28.3', 'Memory CD4 T-cell TFH': '30.2', 'Terminal effector memory CD4 T-cell': '15.2', 'Central memory CD8 T-cell': '15.1', 'Effector memory CD8 T-cell': '13.2', 'Terminal effector memory CD8 T-cell': '14.2', 'Non-switched memory B-cell': '14.7', 'Plasmablast': '13.3', 'Switched memory B-cell': '16.6', 'Exhausted memory B-cell': '13.6', 'Progenitor cell': '18.7', 'Memory T-reg': '30.5', 'Naive CD4 T-cell activated': '34.1', 'Naive CD8 T-cell activated': '38.1', 'Naive T-reg': '33.1'}
null
{'Adipose Tissue': 21.0202707641196, 'Adrenal Gland': 23.672267441860463, 'Bladder': 19.34038095238095, 'Blood': 8.267491065662002, 'Blood Vessel': 15.094898127340825, 'Brain': 10.700985238455717, 'Breast': 18.687971677559915, 'Cervix Uteri': 13.392842105263158, 'Colon': 16.710469833119383, 'Esophagus': 19.569812456747407, 'Fallopian Tube': 14.067777777777778, 'Heart': 11.945405458768873, 'Kidney': 13.110550561797751, 'Liver': 8.231110619469026, 'Lung': 15.002287197231832, 'Muscle': 40.65632627646326, 'Nerve': 17.488529886914378, 'Ovary': 13.667605555555555, 'Pancreas': 6.857868902439024, 'Pituitary': 20.26614840989399, 'Prostate': 14.30794693877551, 'Salivary Gland': 13.765851851851853, 'Skin': 20.260166943062465, 'Small Intestine': 11.706935828877006, 'Spleen': 10.416302904564317, 'Stomach': 11.321465181058496, 'Testis': 16.835429362880888, 'Thyroid': 14.591278713629402, 'Uterus': 14.227330985915492, 'Vagina': 14.943423076923075}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
64.718515
0.670351
1,638
O60260
Q9BXM7
22724072
UbiNet, UbiBrowser, 31181401
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
PINK1
MAVRQALGRGLQLGRALLLRFTGKPGRAYGLGRPGPAAGCVRGERPGWAAGPGAEPRRVGLGLPNRLRFFRQSVAGLAARLQRQFVVRAWGCAGPCGRAVFLAFGLGLGLIEEKQAESRRAVSACQEIQAIFTQKSKPGPDPLDTRRLQGFRLEEYLIGQSIGKGCSAAVYEATMPTLPQNLEVTKSTGLLPGRGPGTSAPGEGQERAPGAPAFPLAIKMMWNISAGSSSEAILNTMSQELVPASRVALAGEYGAVTYRKSKRGPKQLAPHPNIIRVLRAFTSSVPLLPGALVDYPDVLPSRLHPEGLGHGRTLFLVMKNYPCTLRQYLCVNTPSPRLAAMMLLQLLEGVDHLVQQGIAHRDLKSDNILVELDPDGCPWLVIADFGCCLADESIGLQLPFSSWYVDRGGNGCLMAPEVSTARPGPRAVIDYSKADAWAVGAIAYEIFGLVNPFYGQGKAHLESRSYQEAQLPALPESVPPDVRQLVRALLQREASKRPSARVAANVLHLSLWGEHILALKNLKLDKMVGWLLQQSAATLLANRLTEKCCVETKMKMLFLANLECETLCQAALLLCSWRAAL
Homo sapiens
Mitochondrion outer membrane, Mitochondrion inner membrane, Cytoplasm, cytosol
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '22.4', 'Basal respiratory cells': '7.1', 'Club cells': '30.4', 'Ionocytes': '7.4', 'Mucus glandular cells': '45.6', 'Serous glandular cells': '74.2', 'Gastric mucus-secreting cells': '12.4', 'Proximal enterocytes': '62.7', 'Paneth cells': '45.9', 'Distal enterocytes': '85.7', 'Intestinal goblet cells': '39.2', 'Exocrine glandular cells': '-0.180', 'Basal prostatic cells': '48.0', 'Prostatic glandular cells': '40.8', 'Breast glandular cells': '0.081', 'Breast myoepithelial cells': '-0.136', 'Glandular and luminal cells': '28.2', 'Secretory cells': '28.1', 'Basal keratinocytes': '25.7', 'Suprabasal keratinocytes': '58.6', 'Basal squamous epithelial cells': '9.8', 'Squamous epithelial cells': '21.2', 'Alveolar cells type 1': '0.318', 'Alveolar cells type 2': '0.065', 'Salivary duct cells': '43.6', 'Ductal cells': '0.265', 'Hepatocytes': '0.699', 'Cholangiocytes': '32.4', 'Proximal tubular cells': '0.313', 'Distal tubular cells': '67.6', 'Collecting duct cells': '37.0', 'Mesothelial cells': '0.080', 'Sertoli cells': '-0.361', 'Granulosa cells': '29.5', 'Enteroendocrine cells': '24.8', 'Pancreatic endocrine cells': '27.2', 'Leydig cells': '-0.433', 'Excitatory neurons': '26.3', 'Inhibitory neurons': '23.4', 'Cone photoreceptor cells': '124.0', 'Rod photoreceptor cells': '51.0', 'Bipolar cells': '49.5', 'Horizontal cells': '37.8', 'Astrocytes': '15.5', 'Oligodendrocyte precursor cells': '8.0', 'Oligodendrocytes': '13.3', 'Microglial cells': '24.2', 'Muller glia cells': '59.0', 'Schwann cells': '-0.018', 'Spermatogonia': '-0.068', 'Spermatocytes': '0.329', 'Early spermatids': '0.726', 'Late spermatids': '0.552', 'Oocytes': '30.1', 'Cytotrophoblasts': '25.7', 'Syncytiotrophoblasts': '31.5', 'Extravillous trophoblasts': '37.2', 'Endothelial cells': '50.8', 'Lymphatic endothelial cells': '24.4', 'Cardiomyocytes': '0.753', 'Skeletal myocytes': '0.284', 'Smooth muscle cells': '49.3', 'Adipocytes': '37.0', 'Melanocytes': '0.005', 'Fibroblasts': '32.8', 'Peritubular cells': '-0.325', 'Endometrial stromal cells': '15.8', 'Ovarian stromal cells': '25.6', 'Undifferentiated cells': '13.8', 'T-cells': '12.3', 'B-cells': '6.9', 'Plasma cells': '34.1', 'Nk-cells': '11.6', 'Granulocytes': '28.2', 'Monocytes': '11.9', 'Macrophages': '23.0', 'Hofbauer cells': '22.7', 'Kupffer cells': '24.7', 'Dendritic cells': '6.3', 'Langerhans cells': '0.130', 'Erythroid cells': '-0.084', 'Adipocytes (Subcutaneous)': '0.366', 'Adipocytes (Visceral)': '0.263', 'Breast glandular cells (progenitors)': '-0.023', 'Adipocytes (Breast)': '0.269', 'Colon enterocytes': '-0.079', 'Colon enteroendocrine cells': '0.122', 'Enteric glia cells': '-0.267', 'Mitotic cells (Colon)': '-0.111', 'Mitotic cells (Heart)': '0.394', 'Podocytes': '0.000', 'Ascending Loop of Henle cells': '0.394', 'Intercalated cells': '0.141', 'Cholangiocyte': '0.251', 'NK-cells (Liver)': '-0.274', 'Respiratory ciliated cells': '-0.066', 'Mitotic cells (Lung)': '-0.020', 'NK-cells (Lung)': '-0.088', 'B-cells (Lung)': '-0.148', 'Alpha cells': '0.255', 'Beta cells': '0.152', 'Prostate glandular cells': '-0.029', 'Prostate basal glandular cells': '0.089', 'Urothelial cells': '-0.182', 'Keratinocyte (other)': '-0.108', 'Keratinocyte (granular)': '0.337', 'Hair cortex cells': '0.221', 'Inner root sheath cells': '0.140', 'Outer root sheath cells': '0.126', 'Sebaceous gland cells': '0.116', 'Eccrine sweat gland cells': '0.130', 'Adipocytes (Skin)': '0.254', 'Mitotic cells (Skin)': '0.062', 'Parietal cells': '-0.396', 'Chief cells': '-0.391', 'Gastric mucous cells': '-0.448', 'Gastric enteroendocrine cells': '-0.439', 'Mitotic cells (Stomach)': '-0.188', 'Parafollicular cells': '0.032', 'Thyroid glandular cells': '0.398', 'Mitotic cells (Thyroid)': '-0.075', 'Adrenal cortex cells': '0.779', 'Adrenal medulla cells': '0.021', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.313', 'Minor salivary gland ductal cells': '-0.195', 'Minor salivary gland basal cells': '0.337', 'Mitotic cells (Minor salivary gland)': '0.420', 'Adipocytes (Minor salivary gland)': '0.186', 'Somatotropes': '0.073', 'Lactotropes': '-0.047', 'Gonadotropes': '0.141', 'Corticotropes': '-0.159', 'Thyrotropes': '0.053', 'Undifferentiated cells (Pituitary gland)': '0.210', 'Mitotic cells (Spleen)': '-0.216', 'Platelets': '-0.028', 'Erythrocytes': '-0.018', 'Hematopoietic stem cells': '0.014', 'B-cells (Spleen)': '-0.042', 'NK-cells (Spleen)': '0.105', 'Amygdala excitatory': '30.1', 'Cerebellar inhibitory': '33.8', 'Cge interneuron': '41.8', 'Deep-layer corticothalamic and 6b': '38.5', 'Deep-layer intratelencephalic': '40.1', 'Deep-layer near-projecting': '33.7', 'Eccentric medium spiny neuron': '35.1', 'Hippocampal ca1-3': '35.6', 'Hippocampal ca4': '43.7', 'Hippocampal dentate gyrus': '28.9', 'Lamp5-lhx6 and chandelier': '35.3', 'Lower rhombic lip': '60.3', 'Mammillary body': '40.2', 'Medium spiny neuron': '33.7', 'Mge interneuron': '39.9', 'Midbrain-derived inhibitory': '31.6', 'Miscellaneous': '45.8', 'Splatter': '38.4', 'Thalamic excitatory': '47.6', 'Upper rhombic lip': '33.6', 'Upper-layer intratelencephalic': '33.9', 'Astrocyte': '22.9', 'Bergmann glia': '31.6', 'Central nervous system macrophage': '18.3', 'Choroid plexus epithelial cell': '28.6', 'Committed oligodendrocyte precursor': '15.9', 'Ependymal cell': '18.0', 'Oligodendrocyte': '20.5', 'Oligodendrocyte precursor cell': '14.3', 'Endothelial cell': '58.0', 'Pericyte': '30.2', 'Vascular associated smooth muscle cell': '35.6', 'Fibroblast': '20.9', 'Leukocyte': '17.0', 'Basophil': '11.3', 'Eosinophil': '3.7', 'Neutrophil': '63.4', 'Classical monocyte': '6.8', 'Non-classical monocyte': '6.2', 'Intermediate monocyte': '7.8', 'T-reg': '6.2', 'GdT-cell': '0.8', 'MAIT T-cell': '4.6', 'Memory CD4 T-cell': '0.7', 'Naive CD4 T-cell': '4.8', 'Memory CD8 T-cell': '1.1', 'Naive CD8 T-cell': '5.6', 'Memory B-cell': '0.2', 'Naive B-cell': '4.8', 'Plasmacytoid DC': '4.0', 'Myeloid DC': '4.0', 'NK-cell': '6.6', 'Total PBMC': '8.6', 'Vd2 gdTCR': '4.4', 'Memory CD4 T-cell Th1\\/Th17': '3.8', 'Memory CD4 T-cell Th17': '4.4', 'Memory CD4 T-cell Th2': '4.7', 'Non-Vd2 gdTCR': '3.5', 'Memory CD4 T-cell Th1': '5.1', 'Memory CD4 T-cell TFH': '5.9', 'Terminal effector memory CD4 T-cell': '4.9', 'Central memory CD8 T-cell': '2.2', 'Effector memory CD8 T-cell': '3.6', 'Terminal effector memory CD8 T-cell': '4.0', 'Non-switched memory B-cell': '5.4', 'Plasmablast': '7.8', 'Switched memory B-cell': '4.3', 'Exhausted memory B-cell': '2.1', 'Progenitor cell': '6.3', 'Memory T-reg': '7.0', 'Naive CD4 T-cell activated': '1.6', 'Naive CD8 T-cell activated': '2.3', 'Naive T-reg': '5.2'}
null
{'Adipose Tissue': 25.459515780730896, 'Adrenal Gland': 55.78827906976744, 'Bladder': 27.378666666666668, 'Blood': 24.924994079655544, 'Blood Vessel': 32.50990037453183, 'Brain': 45.942120741862226, 'Breast': 24.349287581699347, 'Cervix Uteri': 24.877368421052633, 'Colon': 26.55438767650834, 'Esophagus': 28.25461245674741, 'Fallopian Tube': 23.155555555555555, 'Heart': 28.701275842044137, 'Kidney': 17.723494382022473, 'Liver': 14.570238938053096, 'Lung': 19.345359861591696, 'Muscle': 86.79764632627645, 'Nerve': 33.95411954765751, 'Ovary': 20.80124444444445, 'Pancreas': 7.177064024390244, 'Pituitary': 17.38672438162544, 'Prostate': 21.060714285714287, 'Salivary Gland': 23.392530864197532, 'Skin': 25.778006080707573, 'Small Intestine': 17.321935828877002, 'Spleen': 14.00471369294606, 'Stomach': 20.06638440111421, 'Testis': 63.239171745152355, 'Thyroid': 28.030637059724352, 'Uterus': 28.46516901408451, 'Vagina': 25.94826923076923}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
77.262513
0.404768
1,321
O60260
Q9C037
33082525, 23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
TRIM4
MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHFKQEEKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFFWLSPLASLVIPPVTDRK
Homo sapiens
Cytoplasm
Low tissue specificity
{'Ciliated cells': '13.1', 'Basal respiratory cells': '16.0', 'Club cells': '18.6', 'Ionocytes': '11.4', 'Mucus glandular cells': '18.3', 'Serous glandular cells': '7.9', 'Gastric mucus-secreting cells': '16.5', 'Proximal enterocytes': '14.8', 'Paneth cells': '16.0', 'Distal enterocytes': '7.3', 'Intestinal goblet cells': '9.0', 'Exocrine glandular cells': '-0.627', 'Basal prostatic cells': '31.0', 'Prostatic glandular cells': '30.2', 'Breast glandular cells': '0.607', 'Breast myoepithelial cells': '0.472', 'Glandular and luminal cells': '11.6', 'Secretory cells': '17.6', 'Basal keratinocytes': '19.6', 'Suprabasal keratinocytes': '17.9', 'Basal squamous epithelial cells': '23.3', 'Squamous epithelial cells': '15.4', 'Alveolar cells type 1': '0.090', 'Alveolar cells type 2': '0.050', 'Salivary duct cells': '21.9', 'Ductal cells': '0.536', 'Hepatocytes': '0.502', 'Cholangiocytes': '19.1', 'Proximal tubular cells': '0.242', 'Distal tubular cells': '12.3', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.453', 'Sertoli cells': '0.479', 'Granulosa cells': '25.2', 'Enteroendocrine cells': '8.3', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.459', 'Excitatory neurons': '17.7', 'Inhibitory neurons': '19.8', 'Cone photoreceptor cells': '17.0', 'Rod photoreceptor cells': '20.3', 'Bipolar cells': '20.9', 'Horizontal cells': '10.7', 'Astrocytes': '18.3', 'Oligodendrocyte precursor cells': '21.7', 'Oligodendrocytes': '20.9', 'Microglial cells': '11.6', 'Muller glia cells': '32.1', 'Schwann cells': '0.103', 'Spermatogonia': '0.581', 'Spermatocytes': '0.423', 'Early spermatids': '-0.230', 'Late spermatids': '-0.520', 'Oocytes': '0.7', 'Cytotrophoblasts': '16.0', 'Syncytiotrophoblasts': '15.8', 'Extravillous trophoblasts': '6.8', 'Endothelial cells': '20.4', 'Lymphatic endothelial cells': '14.0', 'Cardiomyocytes': '0.383', 'Skeletal myocytes': '-0.233', 'Smooth muscle cells': '22.1', 'Adipocytes': '18.2', 'Melanocytes': '0.068', 'Fibroblasts': '20.9', 'Peritubular cells': '0.379', 'Endometrial stromal cells': '24.9', 'Ovarian stromal cells': '31.4', 'Undifferentiated cells': '13.8', 'T-cells': '32.6', 'B-cells': '31.9', 'Plasma cells': '16.4', 'Nk-cells': '31.4', 'Granulocytes': '34.2', 'Monocytes': '26.0', 'Macrophages': '19.3', 'Hofbauer cells': '14.6', 'Kupffer cells': '21.3', 'Dendritic cells': '25.2', 'Langerhans cells': '0.246', 'Erythroid cells': '-0.079', 'Adipocytes (Subcutaneous)': '-0.133', 'Adipocytes (Visceral)': '-0.281', 'Breast glandular cells (progenitors)': '0.516', 'Adipocytes (Breast)': '-0.387', 'Colon enterocytes': '-0.164', 'Colon enteroendocrine cells': '0.237', 'Enteric glia cells': '0.029', 'Mitotic cells (Colon)': '-0.121', 'Mitotic cells (Heart)': '0.475', 'Podocytes': '0.004', 'Ascending Loop of Henle cells': '0.461', 'Intercalated cells': '0.091', 'Cholangiocyte': '0.279', 'NK-cells (Liver)': '-0.228', 'Respiratory ciliated cells': '-0.006', 'Mitotic cells (Lung)': '0.001', 'NK-cells (Lung)': '-0.119', 'B-cells (Lung)': '-0.163', 'Alpha cells': '0.344', 'Beta cells': '0.161', 'Prostate glandular cells': '0.057', 'Prostate basal glandular cells': '0.425', 'Urothelial cells': '0.222', 'Keratinocyte (other)': '0.334', 'Keratinocyte (granular)': '0.120', 'Hair cortex cells': '-0.208', 'Inner root sheath cells': '-0.178', 'Outer root sheath cells': '-0.089', 'Sebaceous gland cells': '-0.021', 'Eccrine sweat gland cells': '-0.039', 'Adipocytes (Skin)': '-0.078', 'Mitotic cells (Skin)': '0.194', 'Parietal cells': '-0.454', 'Chief cells': '-0.333', 'Gastric mucous cells': '-0.330', 'Gastric enteroendocrine cells': '-0.298', 'Mitotic cells (Stomach)': '0.006', 'Parafollicular cells': '0.083', 'Thyroid glandular cells': '0.384', 'Mitotic cells (Thyroid)': '-0.002', 'Adrenal cortex cells': '0.602', 'Adrenal medulla cells': '0.059', 'Mitotic cells (Adrenal gland)': '0.455', 'Minor salivary glandular cells': '0.644', 'Minor salivary gland ductal cells': '0.390', 'Minor salivary gland basal cells': '0.066', 'Mitotic cells (Minor salivary gland)': '0.037', 'Adipocytes (Minor salivary gland)': '0.222', 'Somatotropes': '0.270', 'Lactotropes': '0.036', 'Gonadotropes': '-0.023', 'Corticotropes': '-0.149', 'Thyrotropes': '0.054', 'Undifferentiated cells (Pituitary gland)': '0.111', 'Mitotic cells (Spleen)': '-0.203', 'Platelets': '-0.109', 'Erythrocytes': '-0.198', 'Hematopoietic stem cells': '-0.189', 'B-cells (Spleen)': '0.324', 'NK-cells (Spleen)': '0.234', 'Amygdala excitatory': '28.5', 'Cerebellar inhibitory': '28.5', 'Cge interneuron': '27.5', 'Deep-layer corticothalamic and 6b': '24.9', 'Deep-layer intratelencephalic': '26.7', 'Deep-layer near-projecting': '24.8', 'Eccentric medium spiny neuron': '31.2', 'Hippocampal ca1-3': '30.7', 'Hippocampal ca4': '25.6', 'Hippocampal dentate gyrus': '30.1', 'Lamp5-lhx6 and chandelier': '25.0', 'Lower rhombic lip': '24.6', 'Mammillary body': '27.2', 'Medium spiny neuron': '31.9', 'Mge interneuron': '29.2', 'Midbrain-derived inhibitory': '27.0', 'Miscellaneous': '25.1', 'Splatter': '28.3', 'Thalamic excitatory': '28.4', 'Upper rhombic lip': '33.1', 'Upper-layer intratelencephalic': '29.1', 'Astrocyte': '42.8', 'Bergmann glia': '40.0', 'Central nervous system macrophage': '64.9', 'Choroid plexus epithelial cell': '34.5', 'Committed oligodendrocyte precursor': '32.4', 'Ependymal cell': '26.3', 'Oligodendrocyte': '43.6', 'Oligodendrocyte precursor cell': '42.3', 'Endothelial cell': '50.5', 'Pericyte': '50.3', 'Vascular associated smooth muscle cell': '39.6', 'Fibroblast': '46.0', 'Leukocyte': '59.0', 'Basophil': '56.5', 'Eosinophil': '23.7', 'Neutrophil': '34.6', 'Classical monocyte': '19.8', 'Non-classical monocyte': '33.7', 'Intermediate monocyte': '67.6', 'T-reg': '95.5', 'GdT-cell': '28.6', 'MAIT T-cell': '81.1', 'Memory CD4 T-cell': '29.5', 'Naive CD4 T-cell': '59.9', 'Memory CD8 T-cell': '32.6', 'Naive CD8 T-cell': '51.0', 'Memory B-cell': '26.3', 'Naive B-cell': '34.1', 'Plasmacytoid DC': '58.9', 'Myeloid DC': '55.3', 'NK-cell': '32.5', 'Total PBMC': '59.2', 'Vd2 gdTCR': '80.0', 'Memory CD4 T-cell Th1\\/Th17': '41.0', 'Memory CD4 T-cell Th17': '38.5', 'Memory CD4 T-cell Th2': '38.8', 'Non-Vd2 gdTCR': '73.2', 'Memory CD4 T-cell Th1': '37.9', 'Memory CD4 T-cell TFH': '40.1', 'Terminal effector memory CD4 T-cell': '82.5', 'Central memory CD8 T-cell': '88.6', 'Effector memory CD8 T-cell': '62.5', 'Terminal effector memory CD8 T-cell': '73.9', 'Non-switched memory B-cell': '67.6', 'Plasmablast': '35.8', 'Switched memory B-cell': '60.9', 'Exhausted memory B-cell': '72.1', 'Progenitor cell': '51.0', 'Memory T-reg': '33.5', 'Naive CD4 T-cell activated': '38.2', 'Naive CD8 T-cell activated': '48.9', 'Naive T-reg': '62.9'}
null
{'Adipose Tissue': 24.989796511627908, 'Adrenal Gland': 22.669228682170544, 'Bladder': 26.440952380952385, 'Blood': 9.35676512378902, 'Blood Vessel': 30.34813707865169, 'Brain': 8.000211582134748, 'Breast': 28.93556644880174, 'Cervix Uteri': 32.91947368421053, 'Colon': 19.3585648267009, 'Esophagus': 18.568834602076127, 'Fallopian Tube': 32.31111111111111, 'Heart': 5.66145493612079, 'Kidney': 11.122752808988764, 'Liver': 9.291269911504424, 'Lung': 22.19151730103806, 'Muscle': 4.893615193026152, 'Nerve': 32.73657512116316, 'Ovary': 42.98327777777778, 'Pancreas': 10.815335365853658, 'Pituitary': 24.765759717314488, 'Prostate': 25.410204081632653, 'Salivary Gland': 21.737962962962964, 'Skin': 27.65998894416805, 'Small Intestine': 20.16351871657754, 'Spleen': 21.972041493775933, 'Stomach': 17.874211699164345, 'Testis': 20.72260387811634, 'Thyroid': 29.23080245022971, 'Uterus': 34.94380281690141, 'Vagina': 27.225705128205128}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
83.4549
0.43698
1,586
O60260
Q9H0P0
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
NT5C3A
MRAPSMDRAAVARVGAVASASVCALVAGVVLAQYIFTLKRKTGRKTKIIEMMPEFQKSSVRIKNPTRVEEIICGLIKGGAAKLQIITDFDMTLSRFSYKGKRCPTCHNIIDNCKLVTDECRKKLLQLKEKYYAIEVDPVLTVEEKYPYMVEWYTKSHGLLVQQALPKAKLKEIVAESDVMLKEGYENFFDKLQQHSIPVFIFSAGIGDVLEEVIRQAGVYHPNVKVVSNFMDFDETGVLKGFKGELIHVFNKHDGALRNTEYFNQLKDNSNIILLGDSQGDLRMADGVANVEHILKIGYLNDRVDELLEKYMDSYDIVLVQDESLEVANSILQKIL
Homo sapiens
Cytoplasm, Endoplasmic reticulum
Tissue enhanced (skeletal)
{'Ciliated cells': '43.4', 'Basal respiratory cells': '79.1', 'Club cells': '30.3', 'Ionocytes': '41.6', 'Mucus glandular cells': '11.3', 'Serous glandular cells': '13.8', 'Gastric mucus-secreting cells': '43.0', 'Proximal enterocytes': '90.7', 'Paneth cells': '104.3', 'Distal enterocytes': '147.1', 'Intestinal goblet cells': '89.5', 'Exocrine glandular cells': '-0.498', 'Basal prostatic cells': '18.3', 'Prostatic glandular cells': '13.5', 'Breast glandular cells': '0.500', 'Breast myoepithelial cells': '0.510', 'Glandular and luminal cells': '21.1', 'Secretory cells': '33.6', 'Basal keratinocytes': '38.0', 'Suprabasal keratinocytes': '31.1', 'Basal squamous epithelial cells': '46.1', 'Squamous epithelial cells': '32.5', 'Alveolar cells type 1': '0.149', 'Alveolar cells type 2': '-0.363', 'Salivary duct cells': '20.3', 'Ductal cells': '0.452', 'Hepatocytes': '-0.059', 'Cholangiocytes': '34.3', 'Proximal tubular cells': '0.203', 'Distal tubular cells': '27.7', 'Collecting duct cells': '15.6', 'Mesothelial cells': '0.422', 'Sertoli cells': '0.480', 'Granulosa cells': '39.1', 'Enteroendocrine cells': '81.4', 'Pancreatic endocrine cells': '22.1', 'Leydig cells': '0.556', 'Excitatory neurons': '43.8', 'Inhibitory neurons': '47.3', 'Cone photoreceptor cells': '49.3', 'Rod photoreceptor cells': '22.9', 'Bipolar cells': '24.4', 'Horizontal cells': '10.1', 'Astrocytes': '29.1', 'Oligodendrocyte precursor cells': '45.3', 'Oligodendrocytes': '48.7', 'Microglial cells': '27.7', 'Muller glia cells': '19.3', 'Schwann cells': '0.108', 'Spermatogonia': '0.435', 'Spermatocytes': '0.270', 'Early spermatids': '-0.238', 'Late spermatids': '-0.651', 'Oocytes': '20.6', 'Cytotrophoblasts': '37.0', 'Syncytiotrophoblasts': '30.3', 'Extravillous trophoblasts': '31.1', 'Endothelial cells': '34.8', 'Lymphatic endothelial cells': '28.8', 'Cardiomyocytes': '0.580', 'Skeletal myocytes': '0.058', 'Smooth muscle cells': '21.5', 'Adipocytes': '37.7', 'Melanocytes': '0.101', 'Fibroblasts': '27.5', 'Peritubular cells': '0.512', 'Endometrial stromal cells': '19.0', 'Ovarian stromal cells': '34.8', 'Undifferentiated cells': '57.7', 'T-cells': '48.1', 'B-cells': '72.8', 'Plasma cells': '38.9', 'Nk-cells': '58.0', 'Granulocytes': '32.2', 'Monocytes': '54.9', 'Macrophages': '25.1', 'Hofbauer cells': '28.8', 'Kupffer cells': '27.6', 'Dendritic cells': '18.4', 'Langerhans cells': '0.217', 'Erythroid cells': '0.235', 'Adipocytes (Subcutaneous)': '-0.317', 'Adipocytes (Visceral)': '-0.443', 'Breast glandular cells (progenitors)': '0.263', 'Adipocytes (Breast)': '-0.649', 'Colon enterocytes': '0.098', 'Colon enteroendocrine cells': '0.116', 'Enteric glia cells': '0.264', 'Mitotic cells (Colon)': '0.214', 'Mitotic cells (Heart)': '0.446', 'Podocytes': '0.041', 'Ascending Loop of Henle cells': '0.327', 'Intercalated cells': '-0.014', 'Cholangiocyte': '0.284', 'NK-cells (Liver)': '-0.081', 'Respiratory ciliated cells': '0.103', 'Mitotic cells (Lung)': '-0.017', 'NK-cells (Lung)': '0.417', 'B-cells (Lung)': '0.162', 'Alpha cells': '0.300', 'Beta cells': '0.189', 'Prostate glandular cells': '-0.283', 'Prostate basal glandular cells': '0.097', 'Urothelial cells': '0.266', 'Keratinocyte (other)': '0.086', 'Keratinocyte (granular)': '0.051', 'Hair cortex cells': '0.009', 'Inner root sheath cells': '0.070', 'Outer root sheath cells': '0.156', 'Sebaceous gland cells': '0.092', 'Eccrine sweat gland cells': '-0.020', 'Adipocytes (Skin)': '-0.068', 'Mitotic cells (Skin)': '0.212', 'Parietal cells': '-0.241', 'Chief cells': '-0.250', 'Gastric mucous cells': '0.254', 'Gastric enteroendocrine cells': '-0.014', 'Mitotic cells (Stomach)': '0.392', 'Parafollicular cells': '0.062', 'Thyroid glandular cells': '0.299', 'Mitotic cells (Thyroid)': '0.168', 'Adrenal cortex cells': '0.433', 'Adrenal medulla cells': '-0.019', 'Mitotic cells (Adrenal gland)': '0.267', 'Minor salivary glandular cells': '0.311', 'Minor salivary gland ductal cells': '-0.081', 'Minor salivary gland basal cells': '0.567', 'Mitotic cells (Minor salivary gland)': '0.588', 'Adipocytes (Minor salivary gland)': '0.302', 'Somatotropes': '-0.160', 'Lactotropes': '-0.119', 'Gonadotropes': '-0.006', 'Corticotropes': '-0.043', 'Thyrotropes': '0.066', 'Undifferentiated cells (Pituitary gland)': '0.266', 'Mitotic cells (Spleen)': '0.097', 'Platelets': '-0.093', 'Erythrocytes': '0.161', 'Hematopoietic stem cells': '-0.069', 'B-cells (Spleen)': '0.295', 'NK-cells (Spleen)': '0.340', 'Amygdala excitatory': '58.9', 'Cerebellar inhibitory': '61.7', 'Cge interneuron': '66.7', 'Deep-layer corticothalamic and 6b': '68.6', 'Deep-layer intratelencephalic': '58.7', 'Deep-layer near-projecting': '66.2', 'Eccentric medium spiny neuron': '61.6', 'Hippocampal ca1-3': '62.2', 'Hippocampal ca4': '47.8', 'Hippocampal dentate gyrus': '69.0', 'Lamp5-lhx6 and chandelier': '69.8', 'Lower rhombic lip': '53.6', 'Mammillary body': '56.4', 'Medium spiny neuron': '59.3', 'Mge interneuron': '62.1', 'Midbrain-derived inhibitory': '98.2', 'Miscellaneous': '65.8', 'Splatter': '57.6', 'Thalamic excitatory': '57.2', 'Upper rhombic lip': '56.1', 'Upper-layer intratelencephalic': '56.9', 'Astrocyte': '43.8', 'Bergmann glia': '42.1', 'Central nervous system macrophage': '76.2', 'Choroid plexus epithelial cell': '48.6', 'Committed oligodendrocyte precursor': '53.1', 'Ependymal cell': '55.3', 'Oligodendrocyte': '74.8', 'Oligodendrocyte precursor cell': '72.7', 'Endothelial cell': '106.5', 'Pericyte': '62.2', 'Vascular associated smooth muscle cell': '44.2', 'Fibroblast': '66.4', 'Leukocyte': '114.6', 'Basophil': '88.0', 'Eosinophil': '43.8', 'Neutrophil': '493.6', 'Classical monocyte': '23.6', 'Non-classical monocyte': '41.9', 'Intermediate monocyte': '86.8', 'T-reg': '58.8', 'GdT-cell': '12.4', 'MAIT T-cell': '47.3', 'Memory CD4 T-cell': '17.1', 'Naive CD4 T-cell': '53.8', 'Memory CD8 T-cell': '15.9', 'Naive CD8 T-cell': '35.1', 'Memory B-cell': '28.6', 'Naive B-cell': '96.6', 'Plasmacytoid DC': '79.7', 'Myeloid DC': '53.5', 'NK-cell': '32.8', 'Total PBMC': '66.6', 'Vd2 gdTCR': '54.9', 'Memory CD4 T-cell Th1\\/Th17': '57.5', 'Memory CD4 T-cell Th17': '46.1', 'Memory CD4 T-cell Th2': '48.3', 'Non-Vd2 gdTCR': '47.8', 'Memory CD4 T-cell Th1': '41.4', 'Memory CD4 T-cell TFH': '33.7', 'Terminal effector memory CD4 T-cell': '44.8', 'Central memory CD8 T-cell': '46.2', 'Effector memory CD8 T-cell': '70.3', 'Terminal effector memory CD8 T-cell': '39.0', 'Non-switched memory B-cell': '88.6', 'Plasmablast': '326.2', 'Switched memory B-cell': '87.2', 'Exhausted memory B-cell': '76.7', 'Progenitor cell': '78.5', 'Memory T-reg': '35.3', 'Naive CD4 T-cell activated': '54.5', 'Naive CD8 T-cell activated': '45.1', 'Naive T-reg': '55.0'}
2CN1, 2JGA, 2VKQ
{'Adipose Tissue': 21.535567275747507, 'Adrenal Gland': 16.881872093023258, 'Bladder': 19.823333333333338, 'Blood': 34.92925834230355, 'Blood Vessel': 16.533205243445693, 'Brain': 11.714546934140802, 'Breast': 22.70223747276688, 'Cervix Uteri': 28.82684210526316, 'Colon': 22.049059050064187, 'Esophagus': 16.692684429065743, 'Fallopian Tube': 27.502222222222223, 'Heart': 7.801303948896632, 'Kidney': 12.414606741573037, 'Liver': 7.277818584070797, 'Lung': 25.759307958477507, 'Muscle': 34.306399750934, 'Nerve': 26.726607431340874, 'Ovary': 26.340055555555555, 'Pancreas': 12.840981707317072, 'Pituitary': 15.100689045936395, 'Prostate': 19.83827346938776, 'Salivary Gland': 14.821296296296298, 'Skin': 24.272097844112768, 'Small Intestine': 25.566791443850267, 'Spleen': 28.11875518672199, 'Stomach': 13.741008356545962, 'Testis': 14.339224376731302, 'Thyroid': 22.423225114854517, 'Uterus': 28.6206338028169, 'Vagina': 28.15410256410257}
[86.6, 87.14, 88.61, 89.01, 89.67, 88.44, 87.46, 83.77, 82.45, 81.33, 82.97, 84.74, 86.57, 89.57, 90.1, 90.69, 89.67, 90.34, 87.71, 89.23, 89.95, 93.02, 92.3, 92.09, 92.37, 91.58, 92.58, 92.83, 92.29, 90.48, 91.02, 91.12, 88.85, 86.99, 87.58, 87.73, 90.05, 90.01, 88.64, 86.82, 89.42, 87.19, 90.11, 87.28, 86.12, 78.81, 73.0, 79.54, 85.09, 87.69, 88.54, 89.59, 88.97, 88.84, 90.12, 86.33, 83.17, 85.28, 79.1, 80.69, 81.01, 82.27, 82.43, 81.52, 86.22, 87.46, 90.66, 87.7, 89.96, 86.4, 86.05, 77.55, 70.82, 62.18, 61.34, 52.16, 38.83, 44.34, 30.73, 31.43, 26.08, 27.82, 32.43, 27.17, 32.44, 31.46, 28.93, 37.69, 33.58, 33.3, 32.79, 32.77, 31.16, 30.63, 29.11, 31.16, 33.22, 35.12, 33.91, 30.34, 35.05, 29.65, 35.87, 27.96, 32.25, 26.15, 30.35, 26.66, 31.89, 33.33, 30.55, 30.74, 35.12, 32.39, 29.71, 33.62, 34.73, 26.72, 31.71, 28.39, 33.89, 31.11, 34.89, 29.86, 26.98, 29.31, 28.71, 29.87, 26.72, 29.64, 28.01, 35.03, 32.42, 26.03, 26.21, 25.78, 27.97, 25.32, 28.69, 42.33, 50.14, 59.81, 73.34, 80.84, 81.26, 91.68, 94.51, 94.99, 94.31, 93.33, 90.47, 88.44, 92.04, 91.72, 91.25, 91.84, 94.01, 93.92, 93.04, 90.7, 89.16, 91.17, 90.11, 90.68, 90.26, 89.74, 92.18, 92.02, 90.56, 89.44, 86.56, 84.44, 85.5, 85.08, 87.47, 89.13, 87.45, 87.73, 87.57, 91.74, 90.15, 90.56, 90.97, 92.39, 92.62, 91.9, 92.26, 92.16, 91.66, 90.75, 92.44, 91.33, 92.54, 90.83, 90.48, 89.4, 89.6, 84.64, 87.28, 87.95, 84.16, 91.86, 89.62, 92.55, 93.61, 92.4, 93.23, 93.33, 92.76, 93.56, 91.0, 92.54, 89.74, 89.48, 89.91, 88.33, 86.79, 86.93, 80.65, 84.69, 87.55, 91.61, 92.58, 92.61, 93.6, 93.85, 92.89, 94.12, 94.58, 91.59, 90.69, 90.31, 84.69, 83.48, 87.8, 89.95, 93.44, 94.32, 93.73, 90.77, 90.73, 91.35, 92.61, 92.07, 91.36, 91.1, 93.93, 94.82, 95.89, 95.03, 95.16, 92.39, 92.77, 90.89, 89.77, 91.95, 94.22, 94.76, 95.62, 95.26, 94.61, 92.28, 93.2, 95.01, 93.32, 91.52, 93.54, 93.31, 91.4, 89.65, 91.18, 89.05, 88.05, 87.94, 88.85, 89.82, 91.79, 92.63, 92.54, 92.06, 89.88, 89.67, 89.07, 91.55, 93.84, 94.98, 95.12, 95.1, 94.48, 92.52, 90.87, 90.19, 92.01, 91.36, 90.6, 93.83, 94.81, 95.01, 93.21, 91.96, 93.44, 92.68, 94.49, 95.0, 93.51, 92.8, 91.23, 90.04, 89.36, 88.14, 90.5, 92.38, 90.6, 90.2, 92.1, 91.02, 89.08, 89.88, 86.7, 86.54, 88.71, 88.57, 86.26, 88.98, 88.9, 88.32, 88.97, 87.29, 88.96, 89.96, 89.35, 88.03, 85.91, 82.77, 75.14, 75.43, 80.18, 79.23, 84.69, 85.78, 87.42, 87.75, 87.16, 87.6, 84.92, 85.06, 88.44, 89.95, 91.76, 90.7, 90.29, 87.05, 79.67, 62.52, 56.91, 60.2, 56.44, 65.23, 71.08, 83.76, 85.05, 87.42, 91.12, 91.7, 91.75, 88.29, 87.13, 85.75, 85.93, 86.7, 89.58, 90.19, 90.4, 86.67, 89.15, 87.4, 86.34, 78.61, 70.66, 66.43, 65.14, 58.91, 50.78, 46.67, 36.54, 35.27, 32.59, 40.61, 47.31, 50.77, 62.41, 70.48, 78.66, 85.25, 86.67, 88.92, 89.3, 88.85, 87.79, 87.66, 89.94, 91.09, 85.42, 72.16, 57.86, 51.98, 52.44, 47.51, 45.51, 48.58, 51.24, 52.02, 56.52, 70.54, 78.5, 85.42, 88.76, 89.24, 92.22, 89.92, 91.66, 88.73, 88.39, 87.92, 87.02, 85.8, 83.44, 74.02, 80.21, 84.48, 87.59, 88.21, 89.27, 90.78, 91.24, 91.53, 90.4, 90.16, 90.37, 90.19, 90.87, 89.71, 92.15, 92.34, 93.0, 92.02, 89.02, 86.0, 88.39, 88.77, 90.21, 92.62, 91.03, 89.53, 85.52, 87.96, 88.06, 86.94, 83.84, 86.53, 86.56, 87.5, 88.23, 82.06, 76.01]
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[38.74, 39.88, 42.11, 50.17, 47.93, 50.86, 53.19, 54.89, 53.68, 53.99, 55.06, 52.71, 50.13, 52.36, 45.39, 52.1, 54.41, 54.57, 55.73, 56.49, 60.4, 61.24, 66.78, 70.1, 73.07, 75.96, 75.79, 79.9, 83.67, 82.85, 83.59, 82.18, 78.57, 76.91, 77.35, 72.07, 67.85, 57.71, 58.32, 55.9, 51.43, 52.13, 53.88, 53.78, 62.54, 72.29, 80.79, 83.28, 83.96, 83.78, 84.99, 89.87, 93.31, 95.47, 94.59, 93.57, 95.86, 95.02, 97.09, 98.29, 98.07, 97.52, 97.02, 96.68, 95.31, 95.44, 96.08, 97.51, 96.23, 97.23, 98.27, 97.88, 97.23, 97.98, 98.49, 97.95, 97.99, 97.65, 98.21, 97.89, 97.09, 98.06, 98.63, 98.46, 98.8, 98.63, 98.85, 98.71, 98.83, 98.49, 98.28, 98.8, 98.88, 98.75, 98.64, 98.25, 97.57, 97.66, 95.22, 93.08, 96.46, 96.41, 98.21, 98.05, 98.2, 98.64, 98.08, 97.34, 98.48, 98.15, 96.41, 95.03, 97.19, 96.58, 97.06, 97.83, 97.92, 97.41, 97.87, 98.07, 97.44, 97.61, 98.25, 97.8, 96.03, 97.81, 98.19, 95.94, 95.45, 97.53, 97.73, 93.82, 92.89, 95.93, 93.15, 88.41, 88.52, 83.89, 90.76, 93.06, 93.04, 91.11, 93.97, 96.97, 96.26, 95.73, 97.85, 98.13, 97.85, 97.95, 98.4, 98.46, 98.33, 98.24, 98.46, 98.18, 98.43, 98.3, 98.46, 97.98, 98.24, 98.0, 98.11, 96.79, 97.9, 98.03, 98.18, 97.83, 98.22, 98.38, 98.3, 98.48, 98.58, 98.74, 98.4, 98.13, 98.09, 97.52, 98.47, 98.48, 98.8, 98.74, 98.3, 98.51, 98.73, 98.55, 98.46, 98.86, 98.86, 98.38, 98.42, 98.79, 98.53, 98.22, 98.29, 97.75, 98.65, 98.53, 98.77, 98.51, 98.66, 98.1, 98.26, 97.74, 98.16, 98.54, 98.52, 98.65, 98.77, 98.66, 98.69, 98.8, 98.85, 98.68, 98.64, 98.64, 98.48, 98.48, 98.62, 98.52, 98.42, 97.9, 98.05, 98.54, 97.95, 98.07, 97.78, 98.01, 98.23, 98.48, 98.58, 98.45, 98.41, 98.12, 97.67, 97.41, 97.95, 98.38, 98.52, 98.14, 98.21, 98.28, 97.09, 93.46, 93.54, 96.82, 97.45, 96.22, 94.07, 93.47, 95.35, 94.51, 92.91, 91.49, 90.07, 86.72, 90.3, 92.79, 91.13, 90.11, 92.74, 93.92, 93.85, 93.43, 93.91, 93.82, 91.77, 94.19, 96.99, 97.08, 98.56, 98.7, 98.86, 98.86, 98.93, 98.64, 97.88, 95.45, 92.55, 92.78, 97.75, 97.03, 96.1, 97.69, 96.51, 95.45, 93.53, 94.33, 88.68, 89.9, 96.95, 97.72, 98.33, 98.54, 98.79, 98.86, 98.89, 98.79, 98.77, 98.15, 97.33, 93.3, 91.23, 95.47, 95.1, 91.5, 92.81, 96.55, 96.42, 94.28, 97.65, 97.93, 97.61, 96.52, 98.65, 98.62, 98.64, 98.74, 98.77, 98.46, 97.66, 97.95, 97.73, 98.18, 98.64, 97.95, 98.34, 98.52, 98.65, 97.84, 98.2, 98.18, 96.6, 96.37, 97.44, 95.47]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
91.763482
0.330893
2,235
O60260
Q9H1I8
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
ASCC2
MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERATFVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQSRETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
Homo sapiens
Nucleus, Nucleus speckle
Low tissue specificity
{'Ciliated cells': '18.1', 'Basal respiratory cells': '35.7', 'Club cells': '40.1', 'Ionocytes': '56.7', 'Mucus glandular cells': '18.1', 'Serous glandular cells': '17.6', 'Gastric mucus-secreting cells': '59.0', 'Proximal enterocytes': '41.6', 'Paneth cells': '21.1', 'Distal enterocytes': '38.1', 'Intestinal goblet cells': '23.6', 'Exocrine glandular cells': '-0.787', 'Basal prostatic cells': '17.7', 'Prostatic glandular cells': '28.6', 'Breast glandular cells': '0.222', 'Breast myoepithelial cells': '0.170', 'Glandular and luminal cells': '19.0', 'Secretory cells': '12.5', 'Basal keratinocytes': '27.8', 'Suprabasal keratinocytes': '41.1', 'Basal squamous epithelial cells': '19.9', 'Squamous epithelial cells': '36.8', 'Alveolar cells type 1': '-0.066', 'Alveolar cells type 2': '-0.062', 'Salivary duct cells': '16.8', 'Ductal cells': '0.565', 'Hepatocytes': '0.316', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.179', 'Distal tubular cells': '9.2', 'Collecting duct cells': '38.9', 'Mesothelial cells': '0.312', 'Sertoli cells': '-0.304', 'Granulosa cells': '22.3', 'Enteroendocrine cells': '18.8', 'Pancreatic endocrine cells': '34.0', 'Leydig cells': '-0.425', 'Excitatory neurons': '13.0', 'Inhibitory neurons': '13.2', 'Cone photoreceptor cells': '6.8', 'Rod photoreceptor cells': '14.4', 'Bipolar cells': '10.2', 'Horizontal cells': '5.0', 'Astrocytes': '17.6', 'Oligodendrocyte precursor cells': '14.6', 'Oligodendrocytes': '15.2', 'Microglial cells': '10.7', 'Muller glia cells': '11.4', 'Schwann cells': '-0.040', 'Spermatogonia': '-0.202', 'Spermatocytes': '0.132', 'Early spermatids': '0.707', 'Late spermatids': '0.556', 'Oocytes': '61.8', 'Cytotrophoblasts': '45.0', 'Syncytiotrophoblasts': '45.8', 'Extravillous trophoblasts': '68.3', 'Endothelial cells': '19.9', 'Lymphatic endothelial cells': '8.7', 'Cardiomyocytes': '0.509', 'Skeletal myocytes': '-0.447', 'Smooth muscle cells': '16.6', 'Adipocytes': '24.9', 'Melanocytes': '0.316', 'Fibroblasts': '21.8', 'Peritubular cells': '-0.250', 'Endometrial stromal cells': '26.2', 'Ovarian stromal cells': '26.0', 'Undifferentiated cells': '20.2', 'T-cells': '32.4', 'B-cells': '34.0', 'Plasma cells': '27.9', 'Nk-cells': '46.8', 'Granulocytes': '16.5', 'Monocytes': '39.0', 'Macrophages': '27.9', 'Hofbauer cells': '31.3', 'Kupffer cells': '26.0', 'Dendritic cells': '36.9', 'Langerhans cells': '0.206', 'Erythroid cells': '-0.051', 'Adipocytes (Subcutaneous)': '0.267', 'Adipocytes (Visceral)': '0.000', 'Breast glandular cells (progenitors)': '0.102', 'Adipocytes (Breast)': '-0.165', 'Colon enterocytes': '-0.037', 'Colon enteroendocrine cells': '0.075', 'Enteric glia cells': '0.383', 'Mitotic cells (Colon)': '0.072', 'Mitotic cells (Heart)': '0.491', 'Podocytes': '0.002', 'Ascending Loop of Henle cells': '0.433', 'Intercalated cells': '0.021', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.322', 'Respiratory ciliated cells': '0.037', 'Mitotic cells (Lung)': '0.079', 'NK-cells (Lung)': '-0.054', 'B-cells (Lung)': '-0.105', 'Alpha cells': '0.383', 'Beta cells': '0.224', 'Prostate glandular cells': '0.403', 'Prostate basal glandular cells': '0.494', 'Urothelial cells': '0.272', 'Keratinocyte (other)': '0.284', 'Keratinocyte (granular)': '-0.297', 'Hair cortex cells': '0.238', 'Inner root sheath cells': '0.306', 'Outer root sheath cells': '0.365', 'Sebaceous gland cells': '-0.093', 'Eccrine sweat gland cells': '-0.126', 'Adipocytes (Skin)': '-0.284', 'Mitotic cells (Skin)': '0.366', 'Parietal cells': '0.433', 'Chief cells': '0.452', 'Gastric mucous cells': '0.741', 'Gastric enteroendocrine cells': '0.507', 'Mitotic cells (Stomach)': '0.492', 'Parafollicular cells': '0.147', 'Thyroid glandular cells': '0.341', 'Mitotic cells (Thyroid)': '-0.042', 'Adrenal cortex cells': '0.383', 'Adrenal medulla cells': '-0.073', 'Mitotic cells (Adrenal gland)': '-0.035', 'Minor salivary glandular cells': '-0.106', 'Minor salivary gland ductal cells': '-0.045', 'Minor salivary gland basal cells': '0.376', 'Mitotic cells (Minor salivary gland)': '0.240', 'Adipocytes (Minor salivary gland)': '0.066', 'Somatotropes': '0.331', 'Lactotropes': '0.127', 'Gonadotropes': '0.000', 'Corticotropes': '0.060', 'Thyrotropes': '0.136', 'Undifferentiated cells (Pituitary gland)': '-0.173', 'Mitotic cells (Spleen)': '-0.226', 'Platelets': '-0.118', 'Erythrocytes': '0.105', 'Hematopoietic stem cells': '-0.240', 'B-cells (Spleen)': '0.342', 'NK-cells (Spleen)': '0.313', 'Amygdala excitatory': '27.0', 'Cerebellar inhibitory': '22.8', 'Cge interneuron': '22.9', 'Deep-layer corticothalamic and 6b': '28.9', 'Deep-layer intratelencephalic': '27.6', 'Deep-layer near-projecting': '23.0', 'Eccentric medium spiny neuron': '26.3', 'Hippocampal ca1-3': '33.5', 'Hippocampal ca4': '33.9', 'Hippocampal dentate gyrus': '31.2', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '23.5', 'Mammillary body': '25.9', 'Medium spiny neuron': '27.6', 'Mge interneuron': '26.5', 'Midbrain-derived inhibitory': '30.3', 'Miscellaneous': '26.2', 'Splatter': '20.2', 'Thalamic excitatory': '20.3', 'Upper rhombic lip': '19.5', 'Upper-layer intratelencephalic': '24.4', 'Astrocyte': '34.4', 'Bergmann glia': '24.6', 'Central nervous system macrophage': '72.9', 'Choroid plexus epithelial cell': '41.6', 'Committed oligodendrocyte precursor': '32.9', 'Ependymal cell': '19.0', 'Oligodendrocyte': '31.3', 'Oligodendrocyte precursor cell': '33.8', 'Endothelial cell': '34.7', 'Pericyte': '24.6', 'Vascular associated smooth muscle cell': '22.6', 'Fibroblast': '26.4', 'Leukocyte': '47.1', 'Basophil': '81.1', 'Eosinophil': '53.7', 'Neutrophil': '49.4', 'Classical monocyte': '47.2', 'Non-classical monocyte': '64.1', 'Intermediate monocyte': '115.8', 'T-reg': '74.5', 'GdT-cell': '32.2', 'MAIT T-cell': '80.8', 'Memory CD4 T-cell': '23.7', 'Naive CD4 T-cell': '60.6', 'Memory CD8 T-cell': '26.9', 'Naive CD8 T-cell': '63.0', 'Memory B-cell': '18.8', 'Naive B-cell': '45.4', 'Plasmacytoid DC': '100.2', 'Myeloid DC': '84.9', 'NK-cell': '69.0', 'Total PBMC': '106.6', 'Vd2 gdTCR': '74.5', 'Memory CD4 T-cell Th1\\/Th17': '58.7', 'Memory CD4 T-cell Th17': '64.7', 'Memory CD4 T-cell Th2': '66.9', 'Non-Vd2 gdTCR': '81.1', 'Memory CD4 T-cell Th1': '72.4', 'Memory CD4 T-cell TFH': '81.9', 'Terminal effector memory CD4 T-cell': '75.1', 'Central memory CD8 T-cell': '76.1', 'Effector memory CD8 T-cell': '93.5', 'Terminal effector memory CD8 T-cell': '79.0', 'Non-switched memory B-cell': '91.0', 'Plasmablast': '99.6', 'Switched memory B-cell': '76.7', 'Exhausted memory B-cell': '91.3', 'Progenitor cell': '61.0', 'Memory T-reg': '81.2', 'Naive CD4 T-cell activated': '57.5', 'Naive CD8 T-cell activated': '63.0', 'Naive T-reg': '65.7'}
2DI0, 6YXQ
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
77.275495
0.505878
887
O60260
Q9H3K2
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
GHITM
MLAARLVCLRTLPSRVFHPAFTKASPVVKNSITKNQWLLTPSREYATKTRIGIRRGRTGQELKEAALEPSMEKIFKIDQMGRWFVAGGAAVGLGALCYYGLGLSNEIGAIEKAVIWPQYVKDRIHSTYMYLAGSIGLTALSAIAISRTPVLMNFMMRGSWVTIGVTFAAMVGAGMLVRSIPYDQSPGPKHLAWLLHSGVMGAVVAPLTILGGPLLIRAAWYTAGIVGGLSTVAMCAPSEKFLNMGAPLGVGLGLVFVSSLGSMFLPPTTVAGATLYSVAMYGGLVLFSMFLLYDTQKVIKRAEVSPMYGVQKYDPINSMLSIYMDTLNIFMRVATMLATGGNRKK
Homo sapiens
Mitochondrion inner membrane
Low tissue specificity
{'Ciliated cells': '120.1', 'Basal respiratory cells': '426.5', 'Club cells': '185.7', 'Ionocytes': '300.4', 'Mucus glandular cells': '112.1', 'Serous glandular cells': '131.5', 'Gastric mucus-secreting cells': '113.8', 'Proximal enterocytes': '357.8', 'Paneth cells': '261.2', 'Distal enterocytes': '428.1', 'Intestinal goblet cells': '173.1', 'Exocrine glandular cells': '-0.619', 'Basal prostatic cells': '112.9', 'Prostatic glandular cells': '99.4', 'Breast glandular cells': '-0.187', 'Breast myoepithelial cells': '-0.261', 'Glandular and luminal cells': '76.3', 'Secretory cells': '104.4', 'Basal keratinocytes': '191.4', 'Suprabasal keratinocytes': '222.8', 'Basal squamous epithelial cells': '109.3', 'Squamous epithelial cells': '153.1', 'Alveolar cells type 1': '0.058', 'Alveolar cells type 2': '0.373', 'Salivary duct cells': '127.5', 'Ductal cells': '0.561', 'Hepatocytes': '0.615', 'Cholangiocytes': '148.8', 'Proximal tubular cells': '0.433', 'Distal tubular cells': '430.3', 'Collecting duct cells': '163.4', 'Mesothelial cells': '0.019', 'Sertoli cells': '-0.259', 'Granulosa cells': '81.8', 'Enteroendocrine cells': '186.2', 'Pancreatic endocrine cells': '287.0', 'Leydig cells': '-0.307', 'Excitatory neurons': '32.5', 'Inhibitory neurons': '33.1', 'Cone photoreceptor cells': '226.0', 'Rod photoreceptor cells': '118.1', 'Bipolar cells': '130.1', 'Horizontal cells': '97.6', 'Astrocytes': '22.0', 'Oligodendrocyte precursor cells': '13.7', 'Oligodendrocytes': '22.6', 'Microglial cells': '16.1', 'Muller glia cells': '248.8', 'Schwann cells': '0.022', 'Spermatogonia': '-0.015', 'Spermatocytes': '0.218', 'Early spermatids': '0.634', 'Late spermatids': '0.564', 'Oocytes': '277.9', 'Cytotrophoblasts': '267.6', 'Syncytiotrophoblasts': '390.5', 'Extravillous trophoblasts': '245.8', 'Endothelial cells': '114.6', 'Lymphatic endothelial cells': '113.1', 'Cardiomyocytes': '0.781', 'Skeletal myocytes': '-0.001', 'Smooth muscle cells': '120.3', 'Adipocytes': '91.9', 'Melanocytes': '0.098', 'Fibroblasts': '122.7', 'Peritubular cells': '-0.192', 'Endometrial stromal cells': '70.0', 'Ovarian stromal cells': '121.3', 'Undifferentiated cells': '240.8', 'T-cells': '128.7', 'B-cells': '112.0', 'Plasma cells': '208.3', 'Nk-cells': '126.2', 'Granulocytes': '163.2', 'Monocytes': '232.6', 'Macrophages': '144.8', 'Hofbauer cells': '263.5', 'Kupffer cells': '145.0', 'Dendritic cells': '134.0', 'Langerhans cells': '0.194', 'Erythroid cells': '-0.057', 'Adipocytes (Subcutaneous)': '0.405', 'Adipocytes (Visceral)': '0.477', 'Breast glandular cells (progenitors)': '-0.282', 'Adipocytes (Breast)': '0.374', 'Colon enterocytes': '0.046', 'Colon enteroendocrine cells': '0.125', 'Enteric glia cells': '-0.465', 'Mitotic cells (Colon)': '0.045', 'Mitotic cells (Heart)': '0.371', 'Podocytes': '0.208', 'Ascending Loop of Henle cells': '0.236', 'Intercalated cells': '0.209', 'Cholangiocyte': '0.315', 'NK-cells (Liver)': '-0.377', 'Respiratory ciliated cells': '-0.093', 'Mitotic cells (Lung)': '0.175', 'NK-cells (Lung)': '-0.284', 'B-cells (Lung)': '-0.343', 'Alpha cells': '0.366', 'Beta cells': '0.206', 'Prostate glandular cells': '-0.139', 'Prostate basal glandular cells': '0.036', 'Urothelial cells': '-0.045', 'Keratinocyte (other)': '0.093', 'Keratinocyte (granular)': '-0.093', 'Hair cortex cells': '0.027', 'Inner root sheath cells': '0.112', 'Outer root sheath cells': '0.181', 'Sebaceous gland cells': '0.264', 'Eccrine sweat gland cells': '0.117', 'Adipocytes (Skin)': '0.018', 'Mitotic cells (Skin)': '0.279', 'Parietal cells': '0.053', 'Chief cells': '-0.196', 'Gastric mucous cells': '0.098', 'Gastric enteroendocrine cells': '-0.180', 'Mitotic cells (Stomach)': '0.273', 'Parafollicular cells': '0.122', 'Thyroid glandular cells': '0.505', 'Mitotic cells (Thyroid)': '-0.055', 'Adrenal cortex cells': '0.701', 'Adrenal medulla cells': '0.058', 'Mitotic cells (Adrenal gland)': '0.486', 'Minor salivary glandular cells': '0.240', 'Minor salivary gland ductal cells': '-0.200', 'Minor salivary gland basal cells': '0.510', 'Mitotic cells (Minor salivary gland)': '0.626', 'Adipocytes (Minor salivary gland)': '0.234', 'Somatotropes': '0.095', 'Lactotropes': '0.029', 'Gonadotropes': '0.066', 'Corticotropes': '0.080', 'Thyrotropes': '0.206', 'Undifferentiated cells (Pituitary gland)': '0.105', 'Mitotic cells (Spleen)': '0.007', 'Platelets': '0.013', 'Erythrocytes': '-0.118', 'Hematopoietic stem cells': '0.043', 'B-cells (Spleen)': '0.057', 'NK-cells (Spleen)': '0.008', 'Amygdala excitatory': '32.3', 'Cerebellar inhibitory': '61.5', 'Cge interneuron': '47.6', 'Deep-layer corticothalamic and 6b': '44.8', 'Deep-layer intratelencephalic': '45.0', 'Deep-layer near-projecting': '42.7', 'Eccentric medium spiny neuron': '36.3', 'Hippocampal ca1-3': '38.4', 'Hippocampal ca4': '58.6', 'Hippocampal dentate gyrus': '23.8', 'Lamp5-lhx6 and chandelier': '56.4', 'Lower rhombic lip': '73.0', 'Mammillary body': '69.1', 'Medium spiny neuron': '39.8', 'Mge interneuron': '51.8', 'Midbrain-derived inhibitory': '50.9', 'Miscellaneous': '44.6', 'Splatter': '56.2', 'Thalamic excitatory': '64.7', 'Upper rhombic lip': '46.7', 'Upper-layer intratelencephalic': '38.6', 'Astrocyte': '22.7', 'Bergmann glia': '28.9', 'Central nervous system macrophage': '27.9', 'Choroid plexus epithelial cell': '55.2', 'Committed oligodendrocyte precursor': '24.4', 'Ependymal cell': '31.8', 'Oligodendrocyte': '25.5', 'Oligodendrocyte precursor cell': '23.6', 'Endothelial cell': '34.9', 'Pericyte': '44.6', 'Vascular associated smooth muscle cell': '51.0', 'Fibroblast': '27.0', 'Leukocyte': '36.9', 'Basophil': '321.4', 'Eosinophil': '273.4', 'Neutrophil': '466.4', 'Classical monocyte': '304.3', 'Non-classical monocyte': '382.3', 'Intermediate monocyte': '490.7', 'T-reg': '294.4', 'GdT-cell': '171.7', 'MAIT T-cell': '374.4', 'Memory CD4 T-cell': '176.9', 'Naive CD4 T-cell': '230.4', 'Memory CD8 T-cell': '183.2', 'Naive CD8 T-cell': '219.2', 'Memory B-cell': '208.8', 'Naive B-cell': '192.8', 'Plasmacytoid DC': '452.4', 'Myeloid DC': '482.2', 'NK-cell': '288.6', 'Total PBMC': '418.9', 'Vd2 gdTCR': '382.0', 'Memory CD4 T-cell Th1\\/Th17': '273.9', 'Memory CD4 T-cell Th17': '257.3', 'Memory CD4 T-cell Th2': '255.2', 'Non-Vd2 gdTCR': '364.6', 'Memory CD4 T-cell Th1': '228.5', 'Memory CD4 T-cell TFH': '219.5', 'Terminal effector memory CD4 T-cell': '367.0', 'Central memory CD8 T-cell': '290.7', 'Effector memory CD8 T-cell': '408.9', 'Terminal effector memory CD8 T-cell': '403.8', 'Non-switched memory B-cell': '294.5', 'Plasmablast': '703.2', 'Switched memory B-cell': '326.1', 'Exhausted memory B-cell': '316.6', 'Progenitor cell': '243.8', 'Memory T-reg': '232.9', 'Naive CD4 T-cell activated': '497.2', 'Naive CD8 T-cell activated': '467.7', 'Naive T-reg': '231.8'}
null
{'Adipose Tissue': 180.949426910299, 'Adrenal Gland': 295.6772868217054, 'Bladder': 183.95761904761903, 'Blood': 148.58369214208827, 'Blood Vessel': 223.387670411985, 'Brain': 211.61772520817564, 'Breast': 169.56165577342048, 'Cervix Uteri': 165.1315789473684, 'Colon': 221.26124518613608, 'Esophagus': 189.757446366782, 'Fallopian Tube': 166.17777777777778, 'Heart': 230.183587688734, 'Kidney': 208.8465168539326, 'Liver': 167.17398230088494, 'Lung': 175.77043252595155, 'Muscle': 279.3318555417186, 'Nerve': 163.29980613893375, 'Ovary': 161.69761111111112, 'Pancreas': 52.79237804878049, 'Pituitary': 195.07268551236749, 'Prostate': 135.086693877551, 'Salivary Gland': 158.11246913580248, 'Skin': 177.5918463239359, 'Small Intestine': 181.2093582887701, 'Spleen': 144.0033609958506, 'Stomach': 181.17969359331477, 'Testis': 297.34182825484766, 'Thyroid': 181.16664624808575, 'Uterus': 183.49859154929575, 'Vagina': 172.08365384615385}
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[1.0, 1.0, 1.0, 1.0, 1.0, 0.89, 0.98, 0.85, 0.92, 1.0, 0.89, 1.0, 0.91, 0.94, 0.91, 0.81, 0.95, 0.89, 1.0, 1.0, 0.97, 0.99, 0.96, 0.98, 1.0, 1.0, 0.97, 0.95, 0.97, 0.94, 0.87, 0.98, 0.88, 1.0, 1.0, 1.0, 0.93, 0.9, 0.87, 0.82, 0.88, 0.81, 0.89, 0.88, 0.88, 0.92, 0.92, 0.97, 0.98, 0.97, 0.96, 0.76, 0.87, 0.94, 0.92, 0.56, 0.78, 0.64, 0.48, 0.63, 0.61, 0.7, 0.66, 0.5, 0.68, 0.64, 0.75, 0.8, 0.15, 0.37, 0.79, 0.57, 0.54, 0.2, 0.61, 0.57, 0.14, 0.18, 0.46, 0.51, 0.06, 0.49, 0.69, 0.61, 0.29, 0.49, 0.39, 0.38, 0.48, 0.56, 0.69, 0.24, 0.59, 0.42, 0.2, 0.31, 0.57, 0.55, 0.26, 0.57, 0.7, 0.52, 0.6, 0.22, 0.96, 0.61, 0.72, 0.05, 0.08, 0.52, 0.53, 0.36, 0.22, 0.76, 0.81, 0.11, 0.45, 0.65, 0.35, 0.02, 0.33, 0.56, 0.1, 0.11, 0.63, 0.29, 0.01, 0.32, 0.62, 0.17, 0.08, 0.54, 0.34, 0.0, 0.41, 0.41, 0.25, 0.03, 0.47, 0.62, 0.16, 0.07, 0.46, 0.5, 0.11, 0.36, 0.79, 0.4, 0.58, 0.78, 0.48, 0.08, 0.54, 0.4, 0.25, 0.48, 0.77, 0.62, 0.34, 0.73, 0.63, 0.08, 0.42, 0.43, 0.48, 0.2, 0.52, 0.58, 0.35, 0.26, 0.44, 0.43, 0.05, 0.14, 0.63, 0.42, 0.01, 0.62, 0.69, 0.2, 0.4, 0.33, 0.8, 0.83, 0.41, 0.61, 0.65, 0.45, 0.0, 0.32, 0.67, 0.02, 0.15, 0.51, 0.49, 0.03, 0.0, 0.27, 0.21, 0.0, 0.0, 0.16, 0.2, 0.09, 0.0, 0.28, 0.13, 0.29, 0.64, 0.37, 0.29, 0.48, 0.68, 0.23, 0.17, 0.58, 0.64, 0.0, 0.43, 0.75, 0.54, 0.05, 0.44, 0.57, 0.29, 0.15, 0.41, 0.36, 0.18, 0.13, 0.44, 0.07, 0.0, 0.23, 0.11, 0.01, 0.08, 0.27, 0.73, 0.76, 0.19, 0.27, 0.78, 0.31, 0.27, 0.7, 0.65, 0.03, 0.44, 0.71, 0.15, 0.39, 0.39, 0.58, 0.04, 0.5, 0.67, 0.07, 0.24, 0.39, 0.2, 0.28, 0.66, 0.65, 0.43, 0.52, 0.54, 0.71, 0.37, 0.31, 0.46, 0.01, 0.05, 0.36, 0.25, 0.3, 0.11, 0.34, 0.02, 0.2, 0.1, 0.34, 0.01, 0.07, 0.32, 0.2, 0.1, 0.14, 0.41, 0.13, 0.0, 0.09, 0.2, 0.1, 0.01, 0.01, 0.37, 0.05, 0.04, 0.3, 0.43, 0.0, 0.21, 0.66, 0.18, 0.55, 0.59, 0.99, 0.39, 0.96, 0.79, 0.69, 0.07, 0.13, 0.04, 0.0, 0.26, 0.02, 0.01, 0.03, 0.26, 0.02, 0.0, 0.27, 0.07, 0.09, 0.06, 0.18, 0.0, 0.14, 0.21, 0.09, 0.07, 0.0, 0.24, 0.19, 0.32, 0.28, 0.34, 0.32, 0.62, 0.77, 0.63, 0.89, 0.92]
null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
76.67629
0.45429
2,198
O60260
Q9H3S7
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
PTPN23
MEAVPRMPMIWLDLKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRKYLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKSVAHEDIKYEQACILYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLMLGQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEACRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVAYFQSALDKLNEAIKLAKGQPDTVQDALRFTMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKPLPVNPTDPAVTGPDIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAYSHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQEAVGQAGAISITSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVGNLRLLSGPLDQVRAALPTPALSPEDKAVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQDRVLCALTEANVQYAAVRRVLSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAREAARQQLLDRELKKKPPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRGQLGDVGALDTVWRELQDAQEHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYLHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSSSLELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHNGQGLRATRPSDDPLSLLDPLWTLNKT
Homo sapiens
Nucleus, Cytoplasm, Cytoplasmic vesicle, Endosome, Cytoplasm, cytoskeleton, cilium basal body, Early endosome
Low tissue specificity
{'Ciliated cells': '11.3', 'Basal respiratory cells': '6.4', 'Club cells': '12.5', 'Ionocytes': '10.3', 'Mucus glandular cells': '10.2', 'Serous glandular cells': '13.2', 'Gastric mucus-secreting cells': '27.7', 'Proximal enterocytes': '13.9', 'Paneth cells': '14.3', 'Distal enterocytes': '14.1', 'Intestinal goblet cells': '12.8', 'Exocrine glandular cells': '-0.676', 'Basal prostatic cells': '14.4', 'Prostatic glandular cells': '9.2', 'Breast glandular cells': '0.550', 'Breast myoepithelial cells': '0.500', 'Glandular and luminal cells': '20.6', 'Secretory cells': '12.8', 'Basal keratinocytes': '12.3', 'Suprabasal keratinocytes': '18.0', 'Basal squamous epithelial cells': '10.6', 'Squamous epithelial cells': '13.5', 'Alveolar cells type 1': '0.046', 'Alveolar cells type 2': '-0.040', 'Salivary duct cells': '14.8', 'Ductal cells': '0.649', 'Hepatocytes': '0.341', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '0.189', 'Distal tubular cells': '3.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.510', 'Sertoli cells': '0.582', 'Granulosa cells': '10.1', 'Enteroendocrine cells': '8.6', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.467', 'Excitatory neurons': '9.5', 'Inhibitory neurons': '11.5', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '17.3', 'Bipolar cells': '9.7', 'Horizontal cells': '13.2', 'Astrocytes': '16.1', 'Oligodendrocyte precursor cells': '9.0', 'Oligodendrocytes': '13.3', 'Microglial cells': '7.2', 'Muller glia cells': '9.6', 'Schwann cells': '0.181', 'Spermatogonia': '0.466', 'Spermatocytes': '0.265', 'Early spermatids': '-0.540', 'Late spermatids': '-0.594', 'Oocytes': '12.5', 'Cytotrophoblasts': '10.3', 'Syncytiotrophoblasts': '10.0', 'Extravillous trophoblasts': '7.5', 'Endothelial cells': '12.5', 'Lymphatic endothelial cells': '9.8', 'Cardiomyocytes': '0.516', 'Skeletal myocytes': '-0.298', 'Smooth muscle cells': '9.3', 'Adipocytes': '10.1', 'Melanocytes': '0.123', 'Fibroblasts': '10.6', 'Peritubular cells': '0.424', 'Endometrial stromal cells': '13.4', 'Ovarian stromal cells': '9.4', 'Undifferentiated cells': '10.6', 'T-cells': '8.3', 'B-cells': '9.3', 'Plasma cells': '15.1', 'Nk-cells': '6.4', 'Granulocytes': '6.8', 'Monocytes': '12.1', 'Macrophages': '11.6', 'Hofbauer cells': '12.1', 'Kupffer cells': '10.7', 'Dendritic cells': '13.1', 'Langerhans cells': '0.199', 'Erythroid cells': '-0.044', 'Adipocytes (Subcutaneous)': '-0.160', 'Adipocytes (Visceral)': '-0.291', 'Breast glandular cells (progenitors)': '0.385', 'Adipocytes (Breast)': '-0.491', 'Colon enterocytes': '-0.087', 'Colon enteroendocrine cells': '0.179', 'Enteric glia cells': '0.337', 'Mitotic cells (Colon)': '-0.109', 'Mitotic cells (Heart)': '0.519', 'Podocytes': '-0.169', 'Ascending Loop of Henle cells': '0.410', 'Intercalated cells': '-0.087', 'Cholangiocyte': '0.345', 'NK-cells (Liver)': '-0.288', 'Respiratory ciliated cells': '-0.019', 'Mitotic cells (Lung)': '0.024', 'NK-cells (Lung)': '0.064', 'B-cells (Lung)': '-0.063', 'Alpha cells': '0.403', 'Beta cells': '0.295', 'Prostate glandular cells': '-0.058', 'Prostate basal glandular cells': '0.386', 'Urothelial cells': '0.371', 'Keratinocyte (other)': '0.373', 'Keratinocyte (granular)': '0.103', 'Hair cortex cells': '-0.100', 'Inner root sheath cells': '-0.101', 'Outer root sheath cells': '0.016', 'Sebaceous gland cells': '-0.149', 'Eccrine sweat gland cells': '-0.249', 'Adipocytes (Skin)': '-0.221', 'Mitotic cells (Skin)': '0.166', 'Parietal cells': '-0.552', 'Chief cells': '-0.460', 'Gastric mucous cells': '-0.143', 'Gastric enteroendocrine cells': '-0.254', 'Mitotic cells (Stomach)': '0.205', 'Parafollicular cells': '0.092', 'Thyroid glandular cells': '0.179', 'Mitotic cells (Thyroid)': '-0.091', 'Adrenal cortex cells': '0.390', 'Adrenal medulla cells': '0.049', 'Mitotic cells (Adrenal gland)': '0.227', 'Minor salivary glandular cells': '0.442', 'Minor salivary gland ductal cells': '0.102', 'Minor salivary gland basal cells': '0.360', 'Mitotic cells (Minor salivary gland)': '0.370', 'Adipocytes (Minor salivary gland)': '0.161', 'Somatotropes': '0.448', 'Lactotropes': '0.417', 'Gonadotropes': '0.138', 'Corticotropes': '0.127', 'Thyrotropes': '0.186', 'Undifferentiated cells (Pituitary gland)': '-0.306', 'Mitotic cells (Spleen)': '-0.261', 'Platelets': '-0.215', 'Erythrocytes': '-0.045', 'Hematopoietic stem cells': '-0.355', 'B-cells (Spleen)': '0.324', 'NK-cells (Spleen)': '0.311', 'Amygdala excitatory': '16.6', 'Cerebellar inhibitory': '15.6', 'Cge interneuron': '18.8', 'Deep-layer corticothalamic and 6b': '17.5', 'Deep-layer intratelencephalic': '16.8', 'Deep-layer near-projecting': '21.4', 'Eccentric medium spiny neuron': '16.7', 'Hippocampal ca1-3': '15.8', 'Hippocampal ca4': '10.6', 'Hippocampal dentate gyrus': '15.8', 'Lamp5-lhx6 and chandelier': '17.6', 'Lower rhombic lip': '13.4', 'Mammillary body': '15.8', 'Medium spiny neuron': '16.0', 'Mge interneuron': '18.2', 'Midbrain-derived inhibitory': '17.0', 'Miscellaneous': '17.4', 'Splatter': '16.6', 'Thalamic excitatory': '16.1', 'Upper rhombic lip': '15.2', 'Upper-layer intratelencephalic': '16.2', 'Astrocyte': '25.6', 'Bergmann glia': '15.2', 'Central nervous system macrophage': '19.0', 'Choroid plexus epithelial cell': '19.3', 'Committed oligodendrocyte precursor': '23.2', 'Ependymal cell': '13.1', 'Oligodendrocyte': '24.2', 'Oligodendrocyte precursor cell': '19.5', 'Endothelial cell': '16.6', 'Pericyte': '12.2', 'Vascular associated smooth muscle cell': '21.6', 'Fibroblast': '19.3', 'Leukocyte': '17.8', 'Basophil': '5.7', 'Eosinophil': '0.0', 'Neutrophil': '1.6', 'Classical monocyte': '25.2', 'Non-classical monocyte': '28.8', 'Intermediate monocyte': '4.6', 'T-reg': '3.2', 'GdT-cell': '0.1', 'MAIT T-cell': '5.4', 'Memory CD4 T-cell': '0.1', 'Naive CD4 T-cell': '24.3', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '37.3', 'Memory B-cell': '0.3', 'Naive B-cell': '28.2', 'Plasmacytoid DC': '5.4', 'Myeloid DC': '4.0', 'NK-cell': '39.8', 'Total PBMC': '2.1', 'Vd2 gdTCR': '4.6', 'Memory CD4 T-cell Th1\\/Th17': '26.2', 'Memory CD4 T-cell Th17': '35.2', 'Memory CD4 T-cell Th2': '37.1', 'Non-Vd2 gdTCR': '3.6', 'Memory CD4 T-cell Th1': '41.1', 'Memory CD4 T-cell TFH': '50.8', 'Terminal effector memory CD4 T-cell': '6.3', 'Central memory CD8 T-cell': '5.6', 'Effector memory CD8 T-cell': '2.8', 'Terminal effector memory CD8 T-cell': '4.6', 'Non-switched memory B-cell': '3.4', 'Plasmablast': '3.9', 'Switched memory B-cell': '5.3', 'Exhausted memory B-cell': '4.3', 'Progenitor cell': '2.3', 'Memory T-reg': '53.5', 'Naive CD4 T-cell activated': '30.1', 'Naive CD8 T-cell activated': '40.2', 'Naive T-reg': '38.0'}
3RAU, 5CRU, 5CRV, 5LM1, 5LM2, 5MJY, 5MJZ, 5MK0, 5MK1, 5MK2, 5MK3
{'Adipose Tissue': 39.90406976744186, 'Adrenal Gland': 39.407480620155035, 'Bladder': 47.77809523809524, 'Blood': 18.455579763186226, 'Blood Vessel': 44.90335580524345, 'Brain': 28.468531794095384, 'Breast': 42.05315904139434, 'Cervix Uteri': 69.32368421052632, 'Colon': 36.04827984595636, 'Esophagus': 37.851143944636675, 'Fallopian Tube': 54.102222222222224, 'Heart': 15.002953542392566, 'Kidney': 28.25505617977528, 'Liver': 16.202774336283188, 'Lung': 50.74719723183391, 'Muscle': 29.422102117061023, 'Nerve': 69.8873182552504, 'Ovary': 64.98372222222223, 'Pancreas': 19.44709756097561, 'Pituitary': 82.51519434628975, 'Prostate': 50.843102040816326, 'Salivary Gland': 39.30067901234568, 'Skin': 51.996815920398014, 'Small Intestine': 40.92283422459893, 'Spleen': 51.14647302904564, 'Stomach': 29.937103064066857, 'Testis': 52.52401662049861, 'Thyroid': 75.44275650842268, 'Uterus': 65.82408450704226, 'Vagina': 54.80602564102564}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
69.469566
0.544609
162
O60260
Q9H4I3
33082525, 23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
TRABD
MDGEEQQPPHEANVEPVVPSEASEPVPRVLSGDPQNLSDVDAFNLLLEMKLKRRRQRPNLPRTVTQLVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQPDVVVVELCQYRVSMLKMDESTLLREAQELSLEKLQQAVRQNGLMSGLMQMLLLKVSAHITEQLGMAPGGEFREAFKEASKVPFCKFHLGDRPIPVTFKRAIAALSFWQKVRLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMIGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDAEPRKCVPSVVVGVVGMGHVPGIEKNWSTDLNIQEIMTVPPPSVSGRVSRLAVKAAFFGLLGYSLYWMGRRTASLVLSLPAAQYCLQRVTEARHK
Homo sapiens
null
Low tissue specificity
{'Ciliated cells': '21.2', 'Basal respiratory cells': '46.5', 'Club cells': '42.0', 'Ionocytes': '49.7', 'Mucus glandular cells': '24.1', 'Serous glandular cells': '41.0', 'Gastric mucus-secreting cells': '67.2', 'Proximal enterocytes': '56.3', 'Paneth cells': '67.1', 'Distal enterocytes': '48.3', 'Intestinal goblet cells': '52.7', 'Exocrine glandular cells': '-0.509', 'Basal prostatic cells': '35.5', 'Prostatic glandular cells': '23.7', 'Breast glandular cells': '0.671', 'Breast myoepithelial cells': '0.508', 'Glandular and luminal cells': '34.0', 'Secretory cells': '30.4', 'Basal keratinocytes': '46.4', 'Suprabasal keratinocytes': '47.6', 'Basal squamous epithelial cells': '29.7', 'Squamous epithelial cells': '33.5', 'Alveolar cells type 1': '-0.100', 'Alveolar cells type 2': '-0.268', 'Salivary duct cells': '23.9', 'Ductal cells': '0.285', 'Hepatocytes': '0.093', 'Cholangiocytes': '17.2', 'Proximal tubular cells': '0.162', 'Distal tubular cells': '27.7', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.259', 'Sertoli cells': '0.088', 'Granulosa cells': '17.1', 'Enteroendocrine cells': '33.0', 'Pancreatic endocrine cells': '45.8', 'Leydig cells': '0.084', 'Excitatory neurons': '11.3', 'Inhibitory neurons': '12.4', 'Cone photoreceptor cells': '8.5', 'Rod photoreceptor cells': '33.5', 'Bipolar cells': '29.7', 'Horizontal cells': '32.7', 'Astrocytes': '11.5', 'Oligodendrocyte precursor cells': '13.2', 'Oligodendrocytes': '14.2', 'Microglial cells': '8.9', 'Muller glia cells': '21.0', 'Schwann cells': '0.045', 'Spermatogonia': '-0.021', 'Spermatocytes': '0.046', 'Early spermatids': '-0.189', 'Late spermatids': '-0.218', 'Oocytes': '6.6', 'Cytotrophoblasts': '26.7', 'Syncytiotrophoblasts': '29.0', 'Extravillous trophoblasts': '56.5', 'Endothelial cells': '23.0', 'Lymphatic endothelial cells': '10.9', 'Cardiomyocytes': '0.405', 'Skeletal myocytes': '-0.316', 'Smooth muscle cells': '21.0', 'Adipocytes': '20.2', 'Melanocytes': '-0.224', 'Fibroblasts': '23.4', 'Peritubular cells': '0.186', 'Endometrial stromal cells': '24.5', 'Ovarian stromal cells': '23.8', 'Undifferentiated cells': '48.9', 'T-cells': '82.0', 'B-cells': '62.3', 'Plasma cells': '123.3', 'Nk-cells': '117.3', 'Granulocytes': '34.6', 'Monocytes': '85.2', 'Macrophages': '66.9', 'Hofbauer cells': '59.2', 'Kupffer cells': '45.5', 'Dendritic cells': '184.5', 'Langerhans cells': '-0.050', 'Erythroid cells': '-0.024', 'Adipocytes (Subcutaneous)': '-0.143', 'Adipocytes (Visceral)': '-0.185', 'Breast glandular cells (progenitors)': '0.428', 'Adipocytes (Breast)': '-0.584', 'Colon enterocytes': '0.070', 'Colon enteroendocrine cells': '-0.019', 'Enteric glia cells': '0.331', 'Mitotic cells (Colon)': '0.171', 'Mitotic cells (Heart)': '0.393', 'Podocytes': '-0.184', 'Ascending Loop of Henle cells': '0.350', 'Intercalated cells': '-0.123', 'Cholangiocyte': '0.243', 'NK-cells (Liver)': '-0.219', 'Respiratory ciliated cells': '0.035', 'Mitotic cells (Lung)': '-0.058', 'NK-cells (Lung)': '0.266', 'B-cells (Lung)': '0.280', 'Alpha cells': '0.235', 'Beta cells': '0.134', 'Prostate glandular cells': '0.035', 'Prostate basal glandular cells': '0.414', 'Urothelial cells': '0.480', 'Keratinocyte (other)': '-0.139', 'Keratinocyte (granular)': '-0.122', 'Hair cortex cells': '-0.035', 'Inner root sheath cells': '-0.052', 'Outer root sheath cells': '0.069', 'Sebaceous gland cells': '-0.082', 'Eccrine sweat gland cells': '-0.080', 'Adipocytes (Skin)': '-0.065', 'Mitotic cells (Skin)': '-0.113', 'Parietal cells': '0.118', 'Chief cells': '0.326', 'Gastric mucous cells': '0.526', 'Gastric enteroendocrine cells': '0.396', 'Mitotic cells (Stomach)': '0.375', 'Parafollicular cells': '0.025', 'Thyroid glandular cells': '0.002', 'Mitotic cells (Thyroid)': '-0.023', 'Adrenal cortex cells': '0.334', 'Adrenal medulla cells': '0.009', 'Mitotic cells (Adrenal gland)': '-0.193', 'Minor salivary glandular cells': '0.184', 'Minor salivary gland ductal cells': '0.237', 'Minor salivary gland basal cells': '0.097', 'Mitotic cells (Minor salivary gland)': '-0.064', 'Adipocytes (Minor salivary gland)': '-0.017', 'Somatotropes': '-0.018', 'Lactotropes': '-0.078', 'Gonadotropes': '-0.084', 'Corticotropes': '0.052', 'Thyrotropes': '0.082', 'Undifferentiated cells (Pituitary gland)': '0.125', 'Mitotic cells (Spleen)': '-0.162', 'Platelets': '-0.010', 'Erythrocytes': '0.036', 'Hematopoietic stem cells': '-0.053', 'B-cells (Spleen)': '0.173', 'NK-cells (Spleen)': '0.140', 'Amygdala excitatory': '15.0', 'Cerebellar inhibitory': '17.6', 'Cge interneuron': '18.0', 'Deep-layer corticothalamic and 6b': '15.4', 'Deep-layer intratelencephalic': '12.4', 'Deep-layer near-projecting': '25.5', 'Eccentric medium spiny neuron': '21.1', 'Hippocampal ca1-3': '16.6', 'Hippocampal ca4': '12.4', 'Hippocampal dentate gyrus': '14.6', 'Lamp5-lhx6 and chandelier': '18.5', 'Lower rhombic lip': '11.4', 'Mammillary body': '12.7', 'Medium spiny neuron': '22.2', 'Mge interneuron': '20.2', 'Midbrain-derived inhibitory': '14.0', 'Miscellaneous': '16.4', 'Splatter': '12.8', 'Thalamic excitatory': '13.5', 'Upper rhombic lip': '16.1', 'Upper-layer intratelencephalic': '17.2', 'Astrocyte': '25.1', 'Bergmann glia': '20.3', 'Central nervous system macrophage': '49.9', 'Choroid plexus epithelial cell': '16.8', 'Committed oligodendrocyte precursor': '20.8', 'Ependymal cell': '17.6', 'Oligodendrocyte': '19.6', 'Oligodendrocyte precursor cell': '18.1', 'Endothelial cell': '14.4', 'Pericyte': '11.5', 'Vascular associated smooth muscle cell': '11.5', 'Fibroblast': '16.0', 'Leukocyte': '52.1', 'Basophil': '85.2', 'Eosinophil': '51.5', 'Neutrophil': '102.2', 'Classical monocyte': '58.5', 'Non-classical monocyte': '24.0', 'Intermediate monocyte': '75.5', 'T-reg': '62.8', 'GdT-cell': '21.2', 'MAIT T-cell': '60.9', 'Memory CD4 T-cell': '19.2', 'Naive CD4 T-cell': '35.2', 'Memory CD8 T-cell': '19.5', 'Naive CD8 T-cell': '62.4', 'Memory B-cell': '13.7', 'Naive B-cell': '18.3', 'Plasmacytoid DC': '145.5', 'Myeloid DC': '97.0', 'NK-cell': '59.3', 'Total PBMC': '68.4', 'Vd2 gdTCR': '60.2', 'Memory CD4 T-cell Th1\\/Th17': '48.7', 'Memory CD4 T-cell Th17': '77.7', 'Memory CD4 T-cell Th2': '80.7', 'Non-Vd2 gdTCR': '71.3', 'Memory CD4 T-cell Th1': '94.4', 'Memory CD4 T-cell TFH': '143.8', 'Terminal effector memory CD4 T-cell': '67.0', 'Central memory CD8 T-cell': '65.4', 'Effector memory CD8 T-cell': '58.7', 'Terminal effector memory CD8 T-cell': '64.2', 'Non-switched memory B-cell': '33.2', 'Plasmablast': '206.0', 'Switched memory B-cell': '48.8', 'Exhausted memory B-cell': '51.3', 'Progenitor cell': '42.0', 'Memory T-reg': '115.3', 'Naive CD4 T-cell activated': '27.5', 'Naive CD8 T-cell activated': '32.4', 'Naive T-reg': '63.5'}
null
{'Adipose Tissue': 46.894958471760795, 'Adrenal Gland': 35.810271317829454, 'Bladder': 66.78999999999999, 'Blood': 120.01262648008613, 'Blood Vessel': 45.50264419475656, 'Brain': 25.718456850870552, 'Breast': 57.35331154684096, 'Cervix Uteri': 77.71157894736842, 'Colon': 53.03698331193838, 'Esophagus': 55.76995155709343, 'Fallopian Tube': 75.33444444444444, 'Heart': 20.102300813008128, 'Kidney': 40.61337078651685, 'Liver': 33.279646017699115, 'Lung': 91.83980968858133, 'Muscle': 26.861239103362394, 'Nerve': 57.12557350565429, 'Ovary': 65.99722222222222, 'Pancreas': 63.57201219512195, 'Pituitary': 64.2786219081272, 'Prostate': 88.90542857142856, 'Salivary Gland': 66.2277160493827, 'Skin': 57.498446655610834, 'Small Intestine': 98.13737967914436, 'Spleen': 112.19746887966804, 'Stomach': 52.521420612813365, 'Testis': 59.40434903047092, 'Thyroid': 89.94970903522204, 'Uterus': 72.46915492957747, 'Vagina': 79.22051282051282}
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[41.3, 40.41, 36.08, 40.08, 39.76, 38.35, 36.1, 37.58, 37.9, 34.18, 33.67, 34.46, 32.54, 32.07, 30.68, 33.16, 30.28, 31.87, 32.83, 30.94, 31.93, 32.83, 34.19, 33.91, 34.48, 36.51, 38.43, 42.66, 43.52, 45.57, 49.72, 49.19, 50.66, 53.31, 57.04, 63.51, 69.48, 84.05, 81.34, 80.0, 85.07, 87.18, 85.39, 85.57, 89.5, 88.91, 87.83, 87.89, 90.27, 91.1, 89.4, 90.9, 92.62, 93.16, 86.34, 83.93, 89.17, 90.95, 94.22, 96.93, 96.13, 94.82, 94.1, 98.13, 97.8, 97.48, 97.42, 95.61, 92.88, 88.79, 87.99, 92.31, 95.37, 96.93, 98.26, 98.59, 98.61, 98.43, 95.58, 93.79, 89.63, 85.61, 83.98, 87.81, 90.45, 93.42, 93.39, 95.82, 97.65, 98.22, 98.59, 98.57, 98.25, 98.53, 98.45, 96.5, 96.42, 97.29, 97.01, 97.17, 96.18, 98.1, 98.74, 98.66, 98.4, 96.27, 94.98, 93.23, 90.54, 86.05, 87.34, 89.67, 88.18, 85.98, 88.86, 84.71, 84.36, 84.86, 81.09, 82.36, 83.57, 80.69, 77.8, 78.83, 77.08, 72.91, 69.39, 70.79, 66.12, 64.07, 71.09, 78.43, 73.99, 78.42, 82.45, 82.94, 80.51, 84.91, 83.88, 81.41, 82.69, 85.23, 85.64, 84.26, 85.51, 85.57, 84.57, 84.01, 83.26, 80.26, 78.57, 80.67, 80.04, 76.69, 76.29, 79.9, 79.57, 74.58, 73.65, 79.14, 77.99, 74.35, 75.02, 79.5, 81.88, 86.28, 84.63, 87.84, 91.05, 93.87, 96.03, 94.97, 96.42, 98.09, 97.06, 96.7, 97.63, 97.16, 95.96, 96.08, 95.79, 92.76, 91.59, 95.37, 96.34, 97.21, 97.57, 97.3, 95.29, 95.41, 93.38, 90.81, 88.64, 88.36, 89.74, 90.25, 90.71, 89.51, 90.55, 89.48, 88.12, 87.23, 86.34, 85.64, 83.85, 83.0, 83.54, 84.82, 85.68, 84.45, 82.6, 83.18, 82.67, 80.21, 75.02, 77.21, 73.7, 71.2, 62.85, 57.08, 58.86, 52.27, 51.27, 50.69, 53.32, 54.95, 51.55, 51.12, 55.6, 53.2, 47.88, 50.28, 51.76, 48.49, 50.39, 50.01, 49.91, 52.81, 54.55, 55.24, 54.37, 60.47, 60.81, 58.48, 62.16, 67.07, 67.46, 74.35, 78.78, 83.69, 84.25, 84.74, 88.91, 88.48, 88.85, 90.01, 91.57, 94.32, 94.04, 95.77, 96.79, 96.72, 97.37, 98.18, 97.03, 97.44, 98.18, 95.92, 94.87, 95.44, 95.27, 93.23, 90.2, 85.39, 82.33, 75.88, 69.44, 67.88, 67.04, 67.61, 70.35, 74.34, 67.48, 72.84, 73.08, 79.33, 84.37, 88.76, 92.57, 94.4, 96.85, 98.3, 98.79, 98.71, 98.59, 96.87, 92.69, 91.9, 87.63, 93.82, 94.46, 93.01, 94.48, 97.69, 97.6, 96.85, 96.49, 96.69, 92.38, 93.18, 91.34, 92.13, 89.6, 91.05, 88.91, 87.62, 86.91, 87.95, 87.22, 82.41, 77.99, 75.85, 70.48, 72.7, 75.32, 72.01, 72.46, 78.03, 84.4, 78.28, 81.04, 89.33, 90.12, 87.99, 90.63, 95.72, 95.41, 94.68, 95.82, 96.47, 95.91, 95.3, 96.2, 95.34, 93.31, 95.4, 93.94, 92.11, 90.8, 91.56, 90.43, 86.64, 87.04, 85.26, 82.88, 83.37, 83.56, 83.06, 81.9, 86.32, 82.62, 84.3, 77.75, 80.5, 83.78, 80.45, 79.84, 81.34, 83.36, 80.3, 79.96, 80.92, 78.45, 72.77, 70.97, 60.5]
[1.0, 1.0, 0.97, 0.94, 0.95, 0.91, 0.93, 0.93, 0.93, 0.95, 0.93, 0.78, 0.9, 0.86, 0.89, 0.83, 0.88, 0.86, 0.81, 0.86, 0.87, 0.76, 0.84, 0.82, 0.87, 0.84, 0.67, 0.93, 0.81, 0.77, 0.92, 0.66, 0.78, 0.83, 0.92, 0.87, 0.55, 0.43, 0.8, 0.61, 0.51, 0.3, 0.25, 0.49, 0.5, 0.39, 0.24, 0.51, 0.31, 0.02, 0.54, 0.74, 0.52, 0.23, 0.54, 0.86, 0.96, 0.23, 0.63, 0.26, 0.15, 0.97, 0.37, 0.17, 0.2, 0.54, 0.11, 0.57, 0.27, 0.99, 0.27, 0.41, 0.0, 0.4, 0.0, 0.05, 0.01, 0.0, 0.08, 0.03, 0.37, 0.38, 0.24, 0.2, 0.46, 0.53, 0.09, 0.13, 0.61, 0.2, 0.01, 0.18, 0.37, 0.0, 0.0, 0.54, 0.09, 0.04, 0.08, 0.0, 0.08, 0.1, 0.0, 0.06, 0.01, 0.02, 0.0, 0.01, 0.7, 0.67, 0.29, 0.4, 0.47, 0.16, 0.11, 0.87, 0.28, 0.53, 0.35, 0.64, 0.24, 0.11, 0.23, 0.59, 0.39, 0.17, 0.63, 0.55, 0.39, 0.28, 0.62, 0.73, 0.4, 0.18, 0.44, 0.55, 0.07, 0.29, 0.8, 0.7, 0.24, 0.42, 0.6, 0.19, 0.04, 0.0, 0.07, 0.1, 0.38, 0.1, 0.23, 0.48, 0.38, 0.14, 0.25, 0.23, 0.11, 0.18, 0.22, 0.01, 0.68, 0.53, 0.56, 0.57, 0.11, 0.0, 0.22, 0.03, 0.02, 0.01, 0.01, 0.08, 0.22, 0.0, 0.36, 0.51, 0.04, 0.03, 0.67, 0.58, 0.08, 0.21, 0.42, 0.19, 0.55, 0.28, 0.41, 0.3, 0.01, 0.06, 0.02, 0.18, 0.18, 0.17, 0.23, 0.09, 0.11, 0.37, 0.08, 0.0, 0.16, 0.35, 0.29, 0.05, 0.48, 0.71, 0.82, 0.22, 0.28, 0.43, 0.57, 0.08, 0.21, 0.66, 0.34, 0.05, 0.46, 0.56, 0.34, 0.37, 0.58, 0.89, 0.45, 0.43, 0.8, 0.6, 0.29, 0.23, 0.57, 0.57, 0.3, 0.46, 0.62, 0.7, 0.61, 0.27, 0.27, 0.64, 0.5, 0.27, 0.54, 0.56, 0.57, 0.4, 0.48, 0.74, 0.52, 0.07, 0.57, 0.3, 0.04, 0.4, 0.5, 0.0, 0.27, 0.28, 0.37, 0.05, 0.18, 0.07, 0.17, 0.11, 0.02, 0.0, 0.35, 0.26, 0.01, 0.3, 0.34, 0.11, 0.04, 0.63, 0.56, 0.31, 0.66, 0.31, 0.63, 0.44, 0.85, 0.5, 0.81, 0.82, 0.6, 0.83, 0.67, 0.63, 0.42, 0.29, 0.47, 0.03, 0.12, 0.0, 0.0, 0.01, 0.0, 0.02, 0.16, 0.63, 0.69, 0.1, 0.09, 0.58, 0.15, 0.0, 0.45, 0.82, 0.16, 0.09, 0.93, 0.48, 0.99, 0.16, 0.53, 0.15, 0.77, 0.58, 0.07, 0.37, 0.58, 0.48, 0.45, 0.9, 0.51, 0.61, 0.66, 0.66, 0.28, 0.62, 0.6, 0.41, 0.57, 0.68, 0.51, 0.67, 0.55, 0.56, 0.54, 0.69, 0.67, 0.5, 0.65, 0.46, 0.46, 0.61, 0.47, 0.64, 0.65, 0.48, 0.63, 0.4, 0.68, 0.56, 0.45, 0.43, 0.59, 0.63, 0.53, 0.54, 0.54, 0.57, 0.69, 0.61, 0.22, 0.49, 0.55, 0.57, 0.53, 0.6, 0.61, 0.64, 0.53, 0.62, 0.59, 0.86, 0.85, 0.84]
null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
80.353803
0.424415
2,067
O60260
Q9H8Y8
33082525
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
GORASP2
MGSSQSVEIPGGGTEGYHVLRVQENSPGHRAGLEPFFDFIVSINGSRLNKDNDTLKDLLKANVEKPVKMLIYSSKTLELRETSVTPSNLWGGQGLLGVSIRFCSFDGANENVWHVLEVESNSPAALAGLRPHSDYIIGADTVMNESEDLFSLIETHEAKPLKLYVYNTDTDNCREVIITPNSAWGGEGSLGCGIGYGYLHRIPTRPFEEGKKISLPGQMAGTPITPLKDGFTEVQLSSVNPPSLSPPGTTGIEQSLTGLSISSTPPAVSSVLSTGVPTVPLLPPQVNQSLTSVPPMNPATTLPGLMPLPAGLPNLPNLNLNLPAPHIMPGVGLPELVNPGLPPLPSMPPRNLPGIAPLPLPSEFLPSFPLVPESSSAASSGELLSSLPPTSNAPSDPATTTAKADAASSLTVDVTPPTAKAPTTVEDRVGDSTPVSEKPVSAAVDANASESP
Homo sapiens
Golgi apparatus membrane, Endoplasmic reticulum membrane, Golgi apparatus
Low tissue specificity
{'Ciliated cells': '20.4', 'Basal respiratory cells': '78.1', 'Club cells': '49.2', 'Ionocytes': '45.3', 'Mucus glandular cells': '33.4', 'Serous glandular cells': '56.8', 'Gastric mucus-secreting cells': '50.1', 'Proximal enterocytes': '33.6', 'Paneth cells': '44.8', 'Distal enterocytes': '44.9', 'Intestinal goblet cells': '57.2', 'Exocrine glandular cells': '-0.636', 'Basal prostatic cells': '37.4', 'Prostatic glandular cells': '35.2', 'Breast glandular cells': '0.321', 'Breast myoepithelial cells': '0.215', 'Glandular and luminal cells': '33.3', 'Secretory cells': '38.2', 'Basal keratinocytes': '39.0', 'Suprabasal keratinocytes': '51.8', 'Basal squamous epithelial cells': '38.1', 'Squamous epithelial cells': '47.4', 'Alveolar cells type 1': '-0.008', 'Alveolar cells type 2': '0.380', 'Salivary duct cells': '29.7', 'Ductal cells': '0.425', 'Hepatocytes': '0.404', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.192', 'Distal tubular cells': '52.2', 'Collecting duct cells': '15.6', 'Mesothelial cells': '0.271', 'Sertoli cells': '-0.014', 'Granulosa cells': '19.4', 'Enteroendocrine cells': '33.6', 'Pancreatic endocrine cells': '44.1', 'Leydig cells': '-0.061', 'Excitatory neurons': '19.5', 'Inhibitory neurons': '22.0', 'Cone photoreceptor cells': '49.3', 'Rod photoreceptor cells': '28.5', 'Bipolar cells': '27.6', 'Horizontal cells': '17.0', 'Astrocytes': '14.2', 'Oligodendrocyte precursor cells': '25.5', 'Oligodendrocytes': '29.5', 'Microglial cells': '21.5', 'Muller glia cells': '33.8', 'Schwann cells': '0.066', 'Spermatogonia': '0.270', 'Spermatocytes': '0.359', 'Early spermatids': '0.336', 'Late spermatids': '0.297', 'Oocytes': '55.9', 'Cytotrophoblasts': '112.7', 'Syncytiotrophoblasts': '245.4', 'Extravillous trophoblasts': '119.5', 'Endothelial cells': '32.1', 'Lymphatic endothelial cells': '21.8', 'Cardiomyocytes': '0.617', 'Skeletal myocytes': '-0.207', 'Smooth muscle cells': '37.6', 'Adipocytes': '27.5', 'Melanocytes': '0.344', 'Fibroblasts': '47.4', 'Peritubular cells': '-0.040', 'Endometrial stromal cells': '33.3', 'Ovarian stromal cells': '30.1', 'Undifferentiated cells': '45.0', 'T-cells': '38.3', 'B-cells': '39.2', 'Plasma cells': '157.5', 'Nk-cells': '35.0', 'Granulocytes': '19.5', 'Monocytes': '23.4', 'Macrophages': '26.7', 'Hofbauer cells': '38.8', 'Kupffer cells': '19.1', 'Dendritic cells': '92.5', 'Langerhans cells': '0.315', 'Erythroid cells': '-0.129', 'Adipocytes (Subcutaneous)': '-0.014', 'Adipocytes (Visceral)': '-0.023', 'Breast glandular cells (progenitors)': '0.191', 'Adipocytes (Breast)': '-0.115', 'Colon enterocytes': '-0.059', 'Colon enteroendocrine cells': '0.108', 'Enteric glia cells': '-0.312', 'Mitotic cells (Colon)': '-0.062', 'Mitotic cells (Heart)': '0.520', 'Podocytes': '-0.125', 'Ascending Loop of Henle cells': '0.393', 'Intercalated cells': '-0.069', 'Cholangiocyte': '0.267', 'NK-cells (Liver)': '-0.306', 'Respiratory ciliated cells': '-0.202', 'Mitotic cells (Lung)': '0.157', 'NK-cells (Lung)': '-0.248', 'B-cells (Lung)': '-0.249', 'Alpha cells': '0.304', 'Beta cells': '0.102', 'Prostate glandular cells': '-0.062', 'Prostate basal glandular cells': '0.091', 'Urothelial cells': '0.028', 'Keratinocyte (other)': '0.385', 'Keratinocyte (granular)': '0.157', 'Hair cortex cells': '0.032', 'Inner root sheath cells': '0.069', 'Outer root sheath cells': '0.028', 'Sebaceous gland cells': '0.066', 'Eccrine sweat gland cells': '-0.225', 'Adipocytes (Skin)': '-0.205', 'Mitotic cells (Skin)': '0.237', 'Parietal cells': '-0.483', 'Chief cells': '-0.256', 'Gastric mucous cells': '-0.171', 'Gastric enteroendocrine cells': '-0.237', 'Mitotic cells (Stomach)': '0.220', 'Parafollicular cells': '0.128', 'Thyroid glandular cells': '0.437', 'Mitotic cells (Thyroid)': '-0.061', 'Adrenal cortex cells': '0.521', 'Adrenal medulla cells': '0.080', 'Mitotic cells (Adrenal gland)': '0.272', 'Minor salivary glandular cells': '0.162', 'Minor salivary gland ductal cells': '0.145', 'Minor salivary gland basal cells': '0.204', 'Mitotic cells (Minor salivary gland)': '0.091', 'Adipocytes (Minor salivary gland)': '0.014', 'Somatotropes': '0.385', 'Lactotropes': '0.421', 'Gonadotropes': '0.253', 'Corticotropes': '0.137', 'Thyrotropes': '0.250', 'Undifferentiated cells (Pituitary gland)': '-0.273', 'Mitotic cells (Spleen)': '0.165', 'Platelets': '-0.062', 'Erythrocytes': '-0.202', 'Hematopoietic stem cells': '-0.120', 'B-cells (Spleen)': '0.186', 'NK-cells (Spleen)': '-0.009', 'Amygdala excitatory': '29.8', 'Cerebellar inhibitory': '33.1', 'Cge interneuron': '33.0', 'Deep-layer corticothalamic and 6b': '31.0', 'Deep-layer intratelencephalic': '28.7', 'Deep-layer near-projecting': '29.8', 'Eccentric medium spiny neuron': '34.3', 'Hippocampal ca1-3': '30.4', 'Hippocampal ca4': '29.6', 'Hippocampal dentate gyrus': '41.1', 'Lamp5-lhx6 and chandelier': '32.1', 'Lower rhombic lip': '27.1', 'Mammillary body': '25.1', 'Medium spiny neuron': '36.5', 'Mge interneuron': '29.9', 'Midbrain-derived inhibitory': '28.8', 'Miscellaneous': '26.7', 'Splatter': '33.4', 'Thalamic excitatory': '31.4', 'Upper rhombic lip': '40.4', 'Upper-layer intratelencephalic': '25.9', 'Astrocyte': '21.1', 'Bergmann glia': '33.5', 'Central nervous system macrophage': '41.8', 'Choroid plexus epithelial cell': '54.9', 'Committed oligodendrocyte precursor': '40.0', 'Ependymal cell': '20.4', 'Oligodendrocyte': '46.0', 'Oligodendrocyte precursor cell': '42.3', 'Endothelial cell': '40.1', 'Pericyte': '42.0', 'Vascular associated smooth muscle cell': '46.3', 'Fibroblast': '46.9', 'Leukocyte': '45.8', 'Basophil': '80.0', 'Eosinophil': '27.0', 'Neutrophil': '10.3', 'Classical monocyte': '30.4', 'Non-classical monocyte': '35.9', 'Intermediate monocyte': '85.3', 'T-reg': '112.5', 'GdT-cell': '53.1', 'MAIT T-cell': '132.1', 'Memory CD4 T-cell': '59.3', 'Naive CD4 T-cell': '52.5', 'Memory CD8 T-cell': '63.4', 'Naive CD8 T-cell': '47.0', 'Memory B-cell': '44.9', 'Naive B-cell': '27.4', 'Plasmacytoid DC': '240.1', 'Myeloid DC': '106.3', 'NK-cell': '54.8', 'Total PBMC': '91.6', 'Vd2 gdTCR': '106.7', 'Memory CD4 T-cell Th1\\/Th17': '62.1', 'Memory CD4 T-cell Th17': '64.8', 'Memory CD4 T-cell Th2': '67.8', 'Non-Vd2 gdTCR': '86.5', 'Memory CD4 T-cell Th1': '59.5', 'Memory CD4 T-cell TFH': '58.6', 'Terminal effector memory CD4 T-cell': '109.3', 'Central memory CD8 T-cell': '101.1', 'Effector memory CD8 T-cell': '114.7', 'Terminal effector memory CD8 T-cell': '91.8', 'Non-switched memory B-cell': '80.6', 'Plasmablast': '365.6', 'Switched memory B-cell': '94.2', 'Exhausted memory B-cell': '84.3', 'Progenitor cell': '95.7', 'Memory T-reg': '58.2', 'Naive CD4 T-cell activated': '99.5', 'Naive CD8 T-cell activated': '97.7', 'Naive T-reg': '54.6'}
3RLE, 4EDJ
{'Adipose Tissue': 49.23369601328904, 'Adrenal Gland': 53.12806201550388, 'Bladder': 53.49714285714286, 'Blood': 24.79802142088267, 'Blood Vessel': 71.07774531835206, 'Brain': 24.962376608629828, 'Breast': 51.48867102396514, 'Cervix Uteri': 70.15894736842105, 'Colon': 45.84794608472401, 'Esophagus': 48.42651211072664, 'Fallopian Tube': 57.18333333333333, 'Heart': 25.789365853658538, 'Kidney': 25.197674157303368, 'Liver': 27.072676991150445, 'Lung': 53.49387543252595, 'Muscle': 27.741469489414698, 'Nerve': 55.517802907915986, 'Ovary': 54.543277777777774, 'Pancreas': 32.32795731707317, 'Pituitary': 78.24802120141342, 'Prostate': 49.20371428571429, 'Salivary Gland': 59.760493827160495, 'Skin': 62.004853510226646, 'Small Intestine': 42.77155080213904, 'Spleen': 41.09132780082987, 'Stomach': 41.171364902506966, 'Testis': 64.51958448753463, 'Thyroid': 57.372067381316995, 'Uterus': 71.66732394366197, 'Vagina': 57.1998717948718}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
63.797743
0.672898
1,758
O60260
Q9NRD5
17553932
UbiNet, UbiBrowser, 31181401
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
PICK1
MFADLDYDIEEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGLSRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAASEAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVKEMDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQLQRLVSTMSKYYNDCYAVLRDADVFPIEVDLAHTTLAYGLNQEEFTDGEEEEEEEDTAAGEPSRDTRGAAGPLDKGGSWCDS
Homo sapiens
Cytoplasm, perinuclear region, Membrane, Membrane, Postsynaptic density, Synapse, synaptosome, Cytoplasm, cytoskeleton
Low tissue specificity
{'Ciliated cells': '15.3', 'Basal respiratory cells': '14.4', 'Club cells': '16.6', 'Ionocytes': '16.9', 'Mucus glandular cells': '13.4', 'Serous glandular cells': '23.5', 'Gastric mucus-secreting cells': '25.9', 'Proximal enterocytes': '16.4', 'Paneth cells': '18.9', 'Distal enterocytes': '19.2', 'Intestinal goblet cells': '19.6', 'Exocrine glandular cells': '-0.588', 'Basal prostatic cells': '17.1', 'Prostatic glandular cells': '26.5', 'Breast glandular cells': '0.801', 'Breast myoepithelial cells': '0.585', 'Glandular and luminal cells': '17.2', 'Secretory cells': '19.4', 'Basal keratinocytes': '12.5', 'Suprabasal keratinocytes': '14.5', 'Basal squamous epithelial cells': '12.0', 'Squamous epithelial cells': '11.4', 'Alveolar cells type 1': '0.168', 'Alveolar cells type 2': '0.211', 'Salivary duct cells': '10.6', 'Ductal cells': '0.520', 'Hepatocytes': '0.205', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.172', 'Distal tubular cells': '9.2', 'Collecting duct cells': '7.8', 'Mesothelial cells': '0.531', 'Sertoli cells': '-0.535', 'Granulosa cells': '16.5', 'Enteroendocrine cells': '23.9', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '-0.599', 'Excitatory neurons': '25.9', 'Inhibitory neurons': '18.6', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.9', 'Bipolar cells': '12.0', 'Horizontal cells': '20.8', 'Astrocytes': '10.5', 'Oligodendrocyte precursor cells': '8.0', 'Oligodendrocytes': '27.1', 'Microglial cells': '6.3', 'Muller glia cells': '11.7', 'Schwann cells': '0.236', 'Spermatogonia': '-0.492', 'Spermatocytes': '-0.177', 'Early spermatids': '0.483', 'Late spermatids': '0.670', 'Oocytes': '21.3', 'Cytotrophoblasts': '26.0', 'Syncytiotrophoblasts': '37.9', 'Extravillous trophoblasts': '15.6', 'Endothelial cells': '8.2', 'Lymphatic endothelial cells': '12.8', 'Cardiomyocytes': '0.711', 'Skeletal myocytes': '-0.324', 'Smooth muscle cells': '11.0', 'Adipocytes': '7.0', 'Melanocytes': '-0.291', 'Fibroblasts': '7.1', 'Peritubular cells': '-0.422', 'Endometrial stromal cells': '3.4', 'Ovarian stromal cells': '15.7', 'Undifferentiated cells': '16.3', 'T-cells': '7.1', 'B-cells': '11.3', 'Plasma cells': '6.6', 'Nk-cells': '6.9', 'Granulocytes': '5.4', 'Monocytes': '21.0', 'Macrophages': '20.4', 'Hofbauer cells': '13.5', 'Kupffer cells': '23.1', 'Dendritic cells': '5.7', 'Langerhans cells': '-0.229', 'Erythroid cells': '0.051', 'Adipocytes (Subcutaneous)': '0.112', 'Adipocytes (Visceral)': '-0.044', 'Breast glandular cells (progenitors)': '0.554', 'Adipocytes (Breast)': '-0.643', 'Colon enterocytes': '0.142', 'Colon enteroendocrine cells': '0.061', 'Enteric glia cells': '-0.062', 'Mitotic cells (Colon)': '0.057', 'Mitotic cells (Heart)': '0.421', 'Podocytes': '-0.204', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '-0.049', 'Cholangiocyte': '0.315', 'NK-cells (Liver)': '-0.232', 'Respiratory ciliated cells': '0.054', 'Mitotic cells (Lung)': '-0.040', 'NK-cells (Lung)': '-0.185', 'B-cells (Lung)': '-0.182', 'Alpha cells': '0.385', 'Beta cells': '0.311', 'Prostate glandular cells': '0.760', 'Prostate basal glandular cells': '0.506', 'Urothelial cells': '0.049', 'Keratinocyte (other)': '-0.426', 'Keratinocyte (granular)': '-0.148', 'Hair cortex cells': '0.205', 'Inner root sheath cells': '0.157', 'Outer root sheath cells': '0.312', 'Sebaceous gland cells': '0.212', 'Eccrine sweat gland cells': '0.226', 'Adipocytes (Skin)': '0.253', 'Mitotic cells (Skin)': '-0.099', 'Parietal cells': '0.347', 'Chief cells': '0.382', 'Gastric mucous cells': '0.611', 'Gastric enteroendocrine cells': '0.440', 'Mitotic cells (Stomach)': '0.411', 'Parafollicular cells': '0.095', 'Thyroid glandular cells': '0.160', 'Mitotic cells (Thyroid)': '-0.182', 'Adrenal cortex cells': '0.245', 'Adrenal medulla cells': '0.146', 'Mitotic cells (Adrenal gland)': '0.025', 'Minor salivary glandular cells': '0.374', 'Minor salivary gland ductal cells': '0.407', 'Minor salivary gland basal cells': '-0.178', 'Mitotic cells (Minor salivary gland)': '-0.313', 'Adipocytes (Minor salivary gland)': '-0.041', 'Somatotropes': '0.387', 'Lactotropes': '0.247', 'Gonadotropes': '-0.014', 'Corticotropes': '0.313', 'Thyrotropes': '0.106', 'Undifferentiated cells (Pituitary gland)': '-0.460', 'Mitotic cells (Spleen)': '-0.431', 'Platelets': '-0.064', 'Erythrocytes': '-0.138', 'Hematopoietic stem cells': '-0.139', 'B-cells (Spleen)': '0.282', 'NK-cells (Spleen)': '0.187', 'Amygdala excitatory': '26.2', 'Cerebellar inhibitory': '23.0', 'Cge interneuron': '26.0', 'Deep-layer corticothalamic and 6b': '25.7', 'Deep-layer intratelencephalic': '22.1', 'Deep-layer near-projecting': '26.9', 'Eccentric medium spiny neuron': '20.6', 'Hippocampal ca1-3': '35.8', 'Hippocampal ca4': '32.0', 'Hippocampal dentate gyrus': '35.5', 'Lamp5-lhx6 and chandelier': '26.7', 'Lower rhombic lip': '16.4', 'Mammillary body': '22.6', 'Medium spiny neuron': '26.6', 'Mge interneuron': '26.2', 'Midbrain-derived inhibitory': '17.0', 'Miscellaneous': '36.1', 'Splatter': '18.5', 'Thalamic excitatory': '28.8', 'Upper rhombic lip': '18.9', 'Upper-layer intratelencephalic': '34.2', 'Astrocyte': '13.6', 'Bergmann glia': '10.3', 'Central nervous system macrophage': '15.1', 'Choroid plexus epithelial cell': '17.0', 'Committed oligodendrocyte precursor': '21.0', 'Ependymal cell': '12.2', 'Oligodendrocyte': '27.7', 'Oligodendrocyte precursor cell': '9.6', 'Endothelial cell': '10.7', 'Pericyte': '5.4', 'Vascular associated smooth muscle cell': '10.8', 'Fibroblast': '7.2', 'Leukocyte': '10.4', 'Basophil': '4.9', 'Eosinophil': '0.0', 'Neutrophil': '3.0', 'Classical monocyte': '11.7', 'Non-classical monocyte': '5.4', 'Intermediate monocyte': '2.2', 'T-reg': '2.1', 'GdT-cell': '0.5', 'MAIT T-cell': '2.8', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '13.5', 'Memory CD8 T-cell': '1.0', 'Naive CD8 T-cell': '15.1', 'Memory B-cell': '0.3', 'Naive B-cell': '13.9', 'Plasmacytoid DC': '2.6', 'Myeloid DC': '11.0', 'NK-cell': '15.8', 'Total PBMC': '3.5', 'Vd2 gdTCR': '3.2', 'Memory CD4 T-cell Th1\\/Th17': '13.9', 'Memory CD4 T-cell Th17': '16.7', 'Memory CD4 T-cell Th2': '17.1', 'Non-Vd2 gdTCR': '4.8', 'Memory CD4 T-cell Th1': '18.9', 'Memory CD4 T-cell TFH': '23.3', 'Terminal effector memory CD4 T-cell': '5.2', 'Central memory CD8 T-cell': '2.1', 'Effector memory CD8 T-cell': '2.4', 'Terminal effector memory CD8 T-cell': '2.3', 'Non-switched memory B-cell': '3.8', 'Plasmablast': '6.5', 'Switched memory B-cell': '7.1', 'Exhausted memory B-cell': '3.1', 'Progenitor cell': '8.0', 'Memory T-reg': '20.1', 'Naive CD4 T-cell activated': '12.2', 'Naive CD8 T-cell activated': '13.5', 'Naive T-reg': '16.3'}
2GZV, 6AR4, 6BJN, 6BJO
{'Adipose Tissue': 22.674271594684384, 'Adrenal Gland': 29.367868217054266, 'Bladder': 28.21047619047619, 'Blood': 12.810111517761031, 'Blood Vessel': 33.87271086142322, 'Brain': 37.0003485995458, 'Breast': 37.73937908496732, 'Cervix Uteri': 41.36421052631579, 'Colon': 21.306365853658537, 'Esophagus': 27.616080276816607, 'Fallopian Tube': 45.892222222222216, 'Heart': 15.744355400696865, 'Kidney': 24.245955056179778, 'Liver': 16.31758407079646, 'Lung': 40.1006401384083, 'Muscle': 24.223039850560397, 'Nerve': 49.69667205169629, 'Ovary': 62.11516666666667, 'Pancreas': 16.85092987804878, 'Pituitary': 84.78265017667844, 'Prostate': 84.71142857142857, 'Salivary Gland': 38.23882716049383, 'Skin': 31.7790447761194, 'Small Intestine': 27.765561497326203, 'Spleen': 35.90850622406639, 'Stomach': 26.814791086350976, 'Testis': 75.55578947368421, 'Thyroid': 55.164456355283306, 'Uterus': 47.868943661971834, 'Vagina': 38.96089743589744}
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[37.01, 41.35, 43.99, 47.54, 43.7, 49.55, 51.7, 61.62, 64.98, 79.03, 82.39, 85.44, 85.76, 83.21, 83.07, 86.2, 89.58, 90.5, 94.71, 96.06, 96.8, 96.88, 97.25, 97.2, 96.35, 95.97, 93.53, 91.77, 88.83, 88.16, 88.85, 92.45, 94.97, 94.96, 96.42, 95.86, 96.1, 94.05, 92.93, 91.04, 87.79, 86.25, 87.59, 90.75, 89.86, 91.18, 95.89, 96.0, 97.65, 96.38, 95.83, 96.33, 94.65, 91.11, 91.36, 95.15, 96.63, 96.99, 95.33, 95.69, 96.5, 94.93, 96.63, 96.5, 96.49, 96.34, 95.43, 97.07, 96.14, 96.99, 95.92, 95.7, 95.66, 93.56, 90.08, 93.68, 92.78, 93.36, 89.3, 88.18, 93.33, 94.79, 93.02, 94.1, 94.61, 93.64, 93.54, 93.36, 93.12, 93.65, 91.45, 91.82, 90.18, 87.5, 88.89, 93.52, 95.33, 96.87, 97.13, 97.76, 96.72, 95.3, 95.29, 93.62, 90.02, 81.44, 81.77, 74.09, 78.58, 78.85, 78.19, 80.27, 84.5, 85.86, 86.62, 86.25, 87.09, 87.04, 86.5, 86.9, 85.47, 81.83, 81.05, 80.61, 77.86, 75.49, 71.79, 67.65, 69.94, 67.79, 66.03, 67.07, 70.92, 66.95, 67.27, 69.9, 67.09, 63.5, 65.47, 56.9, 56.84, 54.04, 53.47, 55.61, 50.1, 54.97, 67.36, 71.06, 73.15, 73.24, 78.74, 77.72, 80.08, 83.65, 84.1, 83.55, 86.69, 87.83, 84.29, 88.41, 91.46, 87.37, 87.32, 91.86, 91.55, 87.75, 90.32, 93.79, 92.36, 90.44, 93.45, 95.73, 92.25, 92.78, 95.45, 96.03, 94.12, 96.02, 97.75, 95.45, 95.42, 96.99, 97.38, 96.45, 97.16, 97.83, 94.92, 94.94, 96.9, 96.44, 92.91, 93.86, 95.05, 90.21, 88.88, 92.07, 90.49, 85.2, 85.23, 84.79, 85.75, 84.09, 85.86, 87.99, 87.84, 88.29, 90.38, 90.63, 90.37, 90.51, 93.55, 94.47, 94.35, 95.46, 96.17, 96.23, 96.37, 97.0, 96.46, 96.84, 95.18, 94.88, 95.04, 94.75, 94.8, 94.01, 91.96, 91.88, 91.51, 90.28, 89.2, 89.0, 89.48, 88.16, 87.95, 89.76, 89.34, 87.56, 89.0, 90.35, 90.24, 88.01, 87.54, 90.22, 91.01, 89.33, 88.01, 90.13, 90.08, 86.69, 86.94, 90.62, 89.54, 85.35, 88.51, 90.27, 87.03, 88.02, 89.89, 90.32, 87.37, 90.02, 91.27, 90.78, 88.72, 90.24, 91.86, 90.65, 91.82, 93.87, 93.02, 94.2, 93.5, 91.83, 91.75, 94.06, 92.02, 88.33, 90.62, 92.33, 87.0, 88.89, 86.05, 91.71, 91.3, 93.13, 92.46, 90.51, 90.94, 90.84, 93.8, 92.3, 92.07, 94.4, 94.93, 93.78, 94.31, 95.19, 94.79, 94.75, 93.84, 93.65, 93.61, 92.79, 92.12, 93.27, 93.57, 90.79, 90.45, 92.41, 91.53, 88.77, 90.03, 90.68, 89.44, 88.05, 89.87, 87.94, 85.94, 86.33, 86.72, 86.03, 83.58, 82.22, 78.96, 77.76, 75.79, 79.09, 80.87, 82.43, 87.13, 87.1, 86.19, 88.25, 91.16, 89.73, 90.94, 94.0, 95.62, 94.99, 93.94, 97.62, 96.8, 96.49, 96.21, 97.76, 97.18, 95.13, 94.28, 93.57, 92.83, 88.31, 87.9, 83.09, 77.96, 71.38, 68.37, 67.76, 72.76, 64.88, 64.86, 62.91, 65.44, 63.38, 63.01, 57.75, 58.41, 54.82, 53.57, 51.71, 53.44, 47.31, 48.57, 44.86, 44.63, 39.9, 40.03, 41.73, 38.67, 42.07, 37.33, 37.96, 37.17, 35.46, 35.02, 32.38, 31.95, 31.42, 32.03, 33.98, 32.1, 34.27, 30.69, 31.37, 36.03, 29.57, 27.23, 33.13, 32.78, 28.96, 32.97, 29.01, 35.16, 30.12, 33.27, 34.3, 30.95, 36.71, 28.76, 32.17, 34.01, 30.27, 30.17, 35.2, 37.13]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
81.372506
0.41988
1,915
O60260
Q9NUQ2
33082525
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
AGPAT5
MLLSLVLHTYSMRYLLPSVVLLGTAPTYVLAWGVWRLLSAFLPARFYQALDDRLYCVYQSMVLFFFENYTGVQILLYGDLPKNKENIIYLANHQSTVDWIVADILAIRQNALGHVRYVLKEGLKWLPLYGCYFAQHGGIYVKRSAKFNEKEMRNKLQSYVDAGTPMYLVIFPEGTRYNPEQTKVLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDCMKNYLDAIYDVTVVYEGKDDGGQRRESPTMTEFLCKECPKIHIHIDRIDKKDVPEEQEHMRRWLHERFEIKDKMLIEFYESPDPERRKRFPGKSVNSKLSIKKTLPSMLILSGLTAGMLMTDAGRKLYVNTWIYGTLLGCLWVTIKA
Homo sapiens
Endoplasmic reticulum membrane, Nucleus envelope, Mitochondrion
Tissue enhanced (brain)
{'Ciliated cells': '24.7', 'Basal respiratory cells': '15.6', 'Club cells': '9.6', 'Ionocytes': '6.3', 'Mucus glandular cells': '16.1', 'Serous glandular cells': '7.2', 'Gastric mucus-secreting cells': '26.5', 'Proximal enterocytes': '10.3', 'Paneth cells': '17.9', 'Distal enterocytes': '27.0', 'Intestinal goblet cells': '11.3', 'Exocrine glandular cells': '-0.665', 'Basal prostatic cells': '6.4', 'Prostatic glandular cells': '14.9', 'Breast glandular cells': '0.404', 'Breast myoepithelial cells': '0.281', 'Glandular and luminal cells': '95.8', 'Secretory cells': '23.7', 'Basal keratinocytes': '15.8', 'Suprabasal keratinocytes': '16.7', 'Basal squamous epithelial cells': '24.6', 'Squamous epithelial cells': '32.1', 'Alveolar cells type 1': '-0.131', 'Alveolar cells type 2': '-0.118', 'Salivary duct cells': '13.7', 'Ductal cells': '0.549', 'Hepatocytes': '0.246', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.372', 'Distal tubular cells': '9.2', 'Collecting duct cells': '9.7', 'Mesothelial cells': '0.084', 'Sertoli cells': '0.015', 'Granulosa cells': '8.9', 'Enteroendocrine cells': '21.9', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '-0.119', 'Excitatory neurons': '43.5', 'Inhibitory neurons': '44.8', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '10.4', 'Bipolar cells': '11.0', 'Horizontal cells': '9.4', 'Astrocytes': '55.7', 'Oligodendrocyte precursor cells': '53.3', 'Oligodendrocytes': '56.1', 'Microglial cells': '32.2', 'Muller glia cells': '41.5', 'Schwann cells': '0.049', 'Spermatogonia': '0.126', 'Spermatocytes': '0.404', 'Early spermatids': '0.638', 'Late spermatids': '0.198', 'Oocytes': '10.3', 'Cytotrophoblasts': '11.6', 'Syncytiotrophoblasts': '50.5', 'Extravillous trophoblasts': '13.7', 'Endothelial cells': '24.7', 'Lymphatic endothelial cells': '24.6', 'Cardiomyocytes': '0.304', 'Skeletal myocytes': '0.211', 'Smooth muscle cells': '14.9', 'Adipocytes': '17.6', 'Melanocytes': '-0.018', 'Fibroblasts': '13.4', 'Peritubular cells': '-0.104', 'Endometrial stromal cells': '31.5', 'Ovarian stromal cells': '8.7', 'Undifferentiated cells': '32.2', 'T-cells': '21.3', 'B-cells': '45.6', 'Plasma cells': '23.9', 'Nk-cells': '13.8', 'Granulocytes': '44.6', 'Monocytes': '7.8', 'Macrophages': '16.3', 'Hofbauer cells': '12.8', 'Kupffer cells': '20.5', 'Dendritic cells': '150.0', 'Langerhans cells': '-0.038', 'Erythroid cells': '-0.049', 'Adipocytes (Subcutaneous)': '-0.265', 'Adipocytes (Visceral)': '-0.345', 'Breast glandular cells (progenitors)': '0.162', 'Adipocytes (Breast)': '-0.389', 'Colon enterocytes': '0.249', 'Colon enteroendocrine cells': '0.234', 'Enteric glia cells': '0.078', 'Mitotic cells (Colon)': '0.402', 'Mitotic cells (Heart)': '0.462', 'Podocytes': '-0.042', 'Ascending Loop of Henle cells': '0.321', 'Intercalated cells': '-0.061', 'Cholangiocyte': '0.092', 'NK-cells (Liver)': '-0.334', 'Respiratory ciliated cells': '0.028', 'Mitotic cells (Lung)': '0.049', 'NK-cells (Lung)': '0.079', 'B-cells (Lung)': '0.029', 'Alpha cells': '0.344', 'Beta cells': '0.162', 'Prostate glandular cells': '-0.174', 'Prostate basal glandular cells': '0.094', 'Urothelial cells': '0.088', 'Keratinocyte (other)': '-0.240', 'Keratinocyte (granular)': '-0.269', 'Hair cortex cells': '0.245', 'Inner root sheath cells': '0.299', 'Outer root sheath cells': '0.381', 'Sebaceous gland cells': '0.296', 'Eccrine sweat gland cells': '0.205', 'Adipocytes (Skin)': '0.192', 'Mitotic cells (Skin)': '0.232', 'Parietal cells': '0.062', 'Chief cells': '0.113', 'Gastric mucous cells': '0.389', 'Gastric enteroendocrine cells': '0.237', 'Mitotic cells (Stomach)': '0.462', 'Parafollicular cells': '0.179', 'Thyroid glandular cells': '0.357', 'Mitotic cells (Thyroid)': '0.094', 'Adrenal cortex cells': '0.492', 'Adrenal medulla cells': '0.059', 'Mitotic cells (Adrenal gland)': '0.182', 'Minor salivary glandular cells': '0.483', 'Minor salivary gland ductal cells': '-0.082', 'Minor salivary gland basal cells': '0.435', 'Mitotic cells (Minor salivary gland)': '0.503', 'Adipocytes (Minor salivary gland)': '0.150', 'Somatotropes': '-0.134', 'Lactotropes': '-0.092', 'Gonadotropes': '0.010', 'Corticotropes': '0.176', 'Thyrotropes': '0.130', 'Undifferentiated cells (Pituitary gland)': '0.133', 'Mitotic cells (Spleen)': '0.086', 'Platelets': '-0.139', 'Erythrocytes': '-0.170', 'Hematopoietic stem cells': '-0.181', 'B-cells (Spleen)': '0.455', 'NK-cells (Spleen)': '0.213', 'Amygdala excitatory': '79.4', 'Cerebellar inhibitory': '95.3', 'Cge interneuron': '73.2', 'Deep-layer corticothalamic and 6b': '77.6', 'Deep-layer intratelencephalic': '56.7', 'Deep-layer near-projecting': '81.4', 'Eccentric medium spiny neuron': '88.2', 'Hippocampal ca1-3': '74.9', 'Hippocampal ca4': '74.0', 'Hippocampal dentate gyrus': '71.0', 'Lamp5-lhx6 and chandelier': '88.1', 'Lower rhombic lip': '73.5', 'Mammillary body': '87.3', 'Medium spiny neuron': '76.7', 'Mge interneuron': '69.0', 'Midbrain-derived inhibitory': '48.2', 'Miscellaneous': '87.1', 'Splatter': '79.5', 'Thalamic excitatory': '88.7', 'Upper rhombic lip': '69.1', 'Upper-layer intratelencephalic': '55.4', 'Astrocyte': '91.3', 'Bergmann glia': '64.5', 'Central nervous system macrophage': '109.7', 'Choroid plexus epithelial cell': '41.0', 'Committed oligodendrocyte precursor': '76.1', 'Ependymal cell': '164.7', 'Oligodendrocyte': '88.4', 'Oligodendrocyte precursor cell': '89.1', 'Endothelial cell': '22.2', 'Pericyte': '27.2', 'Vascular associated smooth muscle cell': '32.1', 'Fibroblast': '39.8', 'Leukocyte': '43.7', 'Basophil': '8.0', 'Eosinophil': '1.2', 'Neutrophil': '1.4', 'Classical monocyte': '5.2', 'Non-classical monocyte': '11.3', 'Intermediate monocyte': '6.2', 'T-reg': '4.1', 'GdT-cell': '0.7', 'MAIT T-cell': '3.6', 'Memory CD4 T-cell': '1.3', 'Naive CD4 T-cell': '14.2', 'Memory CD8 T-cell': '1.4', 'Naive CD8 T-cell': '15.5', 'Memory B-cell': '4.4', 'Naive B-cell': '81.1', 'Plasmacytoid DC': '11.8', 'Myeloid DC': '5.6', 'NK-cell': '6.2', 'Total PBMC': '5.8', 'Vd2 gdTCR': '3.7', 'Memory CD4 T-cell Th1\\/Th17': '17.4', 'Memory CD4 T-cell Th17': '11.8', 'Memory CD4 T-cell Th2': '12.8', 'Non-Vd2 gdTCR': '2.2', 'Memory CD4 T-cell Th1': '12.1', 'Memory CD4 T-cell TFH': '11.7', 'Terminal effector memory CD4 T-cell': '3.9', 'Central memory CD8 T-cell': '3.5', 'Effector memory CD8 T-cell': '4.7', 'Terminal effector memory CD8 T-cell': '3.3', 'Non-switched memory B-cell': '9.0', 'Plasmablast': '8.0', 'Switched memory B-cell': '8.9', 'Exhausted memory B-cell': '10.0', 'Progenitor cell': '16.3', 'Memory T-reg': '7.8', 'Naive CD4 T-cell activated': '145.9', 'Naive CD8 T-cell activated': '111.8', 'Naive T-reg': '14.5'}
null
{'Adipose Tissue': 8.291831395348837, 'Adrenal Gland': 14.505062015503876, 'Bladder': 8.068666666666667, 'Blood': 18.348863390742732, 'Blood Vessel': 7.297986516853933, 'Brain': 16.892000378501137, 'Breast': 8.144071895424837, 'Cervix Uteri': 12.485947368421051, 'Colon': 7.566913992297818, 'Esophagus': 7.238770242214533, 'Fallopian Tube': 15.154444444444444, 'Heart': 2.2291739837398374, 'Kidney': 6.483573033707866, 'Liver': 5.9937300884955755, 'Lung': 8.296406574394464, 'Muscle': 7.924079701120797, 'Nerve': 12.27254281098546, 'Ovary': 11.103238888888889, 'Pancreas': 3.8457698170731702, 'Pituitary': 17.522173144876323, 'Prostate': 10.713371428571428, 'Salivary Gland': 7.055796296296296, 'Skin': 9.377546710889996, 'Small Intestine': 9.919791443850269, 'Spleen': 7.361265560165975, 'Stomach': 7.957025069637884, 'Testis': 43.83351800554016, 'Thyroid': 8.068480857580399, 'Uterus': 13.168457746478872, 'Vagina': 10.404275641025642}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
94.073764
0.302005
2,120
O60260
Q9NVH0
33082525
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
EXD2
MSRQNLVALTVTTLLGVAVGGFVLWKGIQRRRRSKTSPVTQQPQQKVLGSRELPPPEDDQLHSSAPRSSWKERILKAKVVTVSQEAEWDQIEPLLRSELEDFPVLGIDCEWVNLEGKASPLSLLQMASPSGLCVLVRLPKLICGGKTLPRTLLDILADGTILKVGVGCSEDASKLLQDYGLVVRGCLDLRYLAMRQRNNLLCNGLSLKSLAETVLNFPLDKSLLLRCSNWDAETLTEDQVIYAARDAQISVALFLHLLGYPFSRNSPGEKNDDHSSWRKVLEKCQGVVDIPFRSKGMSRLGEEVNGEATESQQKPRNKKSKMDGMVPGNHQGRDPRKHKRKPLGVGYSARKSPLYDNCFLHAPDGQPLCTCDRRKAQWYLDKGIGELVSEEPFVVKLRFEPAGRPESPGDYYLMVKENLCVVCGKRDSYIRKNVIPHEYRKHFPIEMKDHNSHDVLLLCTSCHAISNYYDNHLKQQLAKEFQAPIGSEEGLRLLEDPERRQVRSGARALLNAESLPTQRKEELLQALREFYNTDVVTEEMLQEAASLETRISNENYVPHGLKVVQCHSQGGLRSLMQLESRWRQHFLDSMQPKHLPQQWSVDHNHQKLLRKFGEDLPIQLS
Homo sapiens
Mitochondrion outer membrane, Mitochondrion matrix, Nucleus, Chromosome
Low tissue specificity
{'Ciliated cells': '10.8', 'Basal respiratory cells': '6.7', 'Club cells': '8.4', 'Ionocytes': '6.3', 'Mucus glandular cells': '8.9', 'Serous glandular cells': '16.1', 'Gastric mucus-secreting cells': '9.4', 'Proximal enterocytes': '3.0', 'Paneth cells': '5.1', 'Distal enterocytes': '4.8', 'Intestinal goblet cells': '7.8', 'Exocrine glandular cells': '-0.607', 'Basal prostatic cells': '7.8', 'Prostatic glandular cells': '10.9', 'Breast glandular cells': '0.513', 'Breast myoepithelial cells': '0.556', 'Glandular and luminal cells': '11.1', 'Secretory cells': '7.2', 'Basal keratinocytes': '5.1', 'Suprabasal keratinocytes': '6.3', 'Basal squamous epithelial cells': '10.4', 'Squamous epithelial cells': '12.7', 'Alveolar cells type 1': '0.218', 'Alveolar cells type 2': '-0.014', 'Salivary duct cells': '8.7', 'Ductal cells': '0.545', 'Hepatocytes': '0.516', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.146', 'Distal tubular cells': '3.1', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.448', 'Sertoli cells': '-0.150', 'Granulosa cells': '10.6', 'Enteroendocrine cells': '10.0', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '-0.187', 'Excitatory neurons': '26.5', 'Inhibitory neurons': '21.7', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '9.5', 'Bipolar cells': '10.2', 'Horizontal cells': '10.7', 'Astrocytes': '14.9', 'Oligodendrocyte precursor cells': '20.3', 'Oligodendrocytes': '17.8', 'Microglial cells': '10.7', 'Muller glia cells': '4.9', 'Schwann cells': '0.177', 'Spermatogonia': '0.154', 'Spermatocytes': '0.605', 'Early spermatids': '0.694', 'Late spermatids': '0.162', 'Oocytes': '6.6', 'Cytotrophoblasts': '8.2', 'Syncytiotrophoblasts': '2.6', 'Extravillous trophoblasts': '4.3', 'Endothelial cells': '6.0', 'Lymphatic endothelial cells': '5.4', 'Cardiomyocytes': '0.645', 'Skeletal myocytes': '-0.033', 'Smooth muscle cells': '7.1', 'Adipocytes': '7.2', 'Melanocytes': '0.210', 'Fibroblasts': '6.7', 'Peritubular cells': '-0.137', 'Endometrial stromal cells': '7.8', 'Ovarian stromal cells': '5.3', 'Undifferentiated cells': '8.8', 'T-cells': '3.0', 'B-cells': '5.0', 'Plasma cells': '7.4', 'Nk-cells': '1.4', 'Granulocytes': '8.8', 'Monocytes': '0.4', 'Macrophages': '4.6', 'Hofbauer cells': '5.4', 'Kupffer cells': '6.6', 'Dendritic cells': '11.1', 'Langerhans cells': '0.288', 'Erythroid cells': '0.031', 'Adipocytes (Subcutaneous)': '0.002', 'Adipocytes (Visceral)': '-0.180', 'Breast glandular cells (progenitors)': '0.416', 'Adipocytes (Breast)': '-0.480', 'Colon enterocytes': '-0.155', 'Colon enteroendocrine cells': '0.229', 'Enteric glia cells': '0.105', 'Mitotic cells (Colon)': '-0.131', 'Mitotic cells (Heart)': '0.508', 'Podocytes': '-0.161', 'Ascending Loop of Henle cells': '0.567', 'Intercalated cells': '0.045', 'Cholangiocyte': '0.310', 'NK-cells (Liver)': '-0.232', 'Respiratory ciliated cells': '0.070', 'Mitotic cells (Lung)': '0.071', 'NK-cells (Lung)': '0.038', 'B-cells (Lung)': '-0.130', 'Alpha cells': '0.359', 'Beta cells': '0.230', 'Prostate glandular cells': '-0.035', 'Prostate basal glandular cells': '0.190', 'Urothelial cells': '0.072', 'Keratinocyte (other)': '0.259', 'Keratinocyte (granular)': '-0.247', 'Hair cortex cells': '0.048', 'Inner root sheath cells': '0.118', 'Outer root sheath cells': '0.326', 'Sebaceous gland cells': '0.140', 'Eccrine sweat gland cells': '0.138', 'Adipocytes (Skin)': '-0.051', 'Mitotic cells (Skin)': '0.525', 'Parietal cells': '-0.329', 'Chief cells': '-0.093', 'Gastric mucous cells': '-0.344', 'Gastric enteroendocrine cells': '-0.117', 'Mitotic cells (Stomach)': '-0.037', 'Parafollicular cells': '0.065', 'Thyroid glandular cells': '0.454', 'Mitotic cells (Thyroid)': '0.070', 'Adrenal cortex cells': '0.593', 'Adrenal medulla cells': '0.053', 'Mitotic cells (Adrenal gland)': '0.435', 'Minor salivary glandular cells': '0.574', 'Minor salivary gland ductal cells': '0.319', 'Minor salivary gland basal cells': '0.069', 'Mitotic cells (Minor salivary gland)': '0.151', 'Adipocytes (Minor salivary gland)': '0.018', 'Somatotropes': '0.160', 'Lactotropes': '0.212', 'Gonadotropes': '0.186', 'Corticotropes': '0.071', 'Thyrotropes': '0.341', 'Undifferentiated cells (Pituitary gland)': '0.112', 'Mitotic cells (Spleen)': '-0.230', 'Platelets': '-0.193', 'Erythrocytes': '-0.084', 'Hematopoietic stem cells': '-0.273', 'B-cells (Spleen)': '0.206', 'NK-cells (Spleen)': '0.312', 'Amygdala excitatory': '38.5', 'Cerebellar inhibitory': '48.2', 'Cge interneuron': '33.9', 'Deep-layer corticothalamic and 6b': '39.8', 'Deep-layer intratelencephalic': '43.5', 'Deep-layer near-projecting': '50.1', 'Eccentric medium spiny neuron': '44.2', 'Hippocampal ca1-3': '40.8', 'Hippocampal ca4': '34.9', 'Hippocampal dentate gyrus': '34.0', 'Lamp5-lhx6 and chandelier': '34.0', 'Lower rhombic lip': '55.9', 'Mammillary body': '46.7', 'Medium spiny neuron': '46.6', 'Mge interneuron': '36.4', 'Midbrain-derived inhibitory': '25.7', 'Miscellaneous': '44.0', 'Splatter': '39.2', 'Thalamic excitatory': '43.5', 'Upper rhombic lip': '46.6', 'Upper-layer intratelencephalic': '44.8', 'Astrocyte': '25.5', 'Bergmann glia': '30.2', 'Central nervous system macrophage': '23.6', 'Choroid plexus epithelial cell': '38.3', 'Committed oligodendrocyte precursor': '28.5', 'Ependymal cell': '27.9', 'Oligodendrocyte': '31.0', 'Oligodendrocyte precursor cell': '33.6', 'Endothelial cell': '23.4', 'Pericyte': '26.8', 'Vascular associated smooth muscle cell': '22.0', 'Fibroblast': '27.1', 'Leukocyte': '13.1', 'Basophil': '13.0', 'Eosinophil': '2.1', 'Neutrophil': '0.1', 'Classical monocyte': '3.4', 'Non-classical monocyte': '4.4', 'Intermediate monocyte': '7.8', 'T-reg': '10.9', 'GdT-cell': '2.3', 'MAIT T-cell': '7.8', 'Memory CD4 T-cell': '2.4', 'Naive CD4 T-cell': '15.2', 'Memory CD8 T-cell': '2.3', 'Naive CD8 T-cell': '13.2', 'Memory B-cell': '2.9', 'Naive B-cell': '9.2', 'Plasmacytoid DC': '17.8', 'Myeloid DC': '9.2', 'NK-cell': '4.7', 'Total PBMC': '6.8', 'Vd2 gdTCR': '6.0', 'Memory CD4 T-cell Th1\\/Th17': '11.3', 'Memory CD4 T-cell Th17': '9.6', 'Memory CD4 T-cell Th2': '10.7', 'Non-Vd2 gdTCR': '3.3', 'Memory CD4 T-cell Th1': '11.0', 'Memory CD4 T-cell TFH': '11.0', 'Terminal effector memory CD4 T-cell': '8.5', 'Central memory CD8 T-cell': '12.6', 'Effector memory CD8 T-cell': '5.3', 'Terminal effector memory CD8 T-cell': '4.4', 'Non-switched memory B-cell': '10.8', 'Plasmablast': '17.7', 'Switched memory B-cell': '8.6', 'Exhausted memory B-cell': '6.4', 'Progenitor cell': '26.7', 'Memory T-reg': '6.4', 'Naive CD4 T-cell activated': '4.0', 'Naive CD8 T-cell activated': '4.8', 'Naive T-reg': '14.3'}
6K17, 6K18, 6K19, 6K1A, 6K1B, 6K1C, 6K1D, 6K1E
{'Adipose Tissue': 10.830940199335547, 'Adrenal Gland': 7.587972868217053, 'Bladder': 13.880238095238097, 'Blood': 1.979176878363832, 'Blood Vessel': 12.858774531835206, 'Brain': 13.449867146101438, 'Breast': 12.342880174291938, 'Cervix Uteri': 16.32015789473684, 'Colon': 12.680463414634149, 'Esophagus': 13.757608996539792, 'Fallopian Tube': 15.346666666666668, 'Heart': 4.933058304297329, 'Kidney': 6.586606741573033, 'Liver': 3.230618584070797, 'Lung': 11.467690311418686, 'Muscle': 6.283004981320049, 'Nerve': 16.642176090468496, 'Ovary': 14.03985, 'Pancreas': 9.850103658536584, 'Pituitary': 14.664254416961132, 'Prostate': 12.79328163265306, 'Salivary Gland': 12.143314814814817, 'Skin': 11.714155334438916, 'Small Intestine': 8.329663101604277, 'Spleen': 7.12582572614108, 'Stomach': 10.68483844011142, 'Testis': 19.333908587257618, 'Thyroid': 15.41793568147014, 'Uterus': 18.002640845070424, 'Vagina': 13.257583333333333}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
79.073527
0.420531
1,198
O60260
Q9NX09
25101677
UbiNet, UbiBrowser, 31181401
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
DDIT4
MPSLWDRFSSSSTSSSPSSLPRTPTPDRPPRSAWGSATREEGFDRSTSLESSDCESLDSSNSGFGPEEDTAYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLAQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVGQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLFSSANSPFLPGFSQSLTLSTGFRVIKKKLYSSEQLLIEEC
Homo sapiens
Mitochondrion, Cytoplasm, cytosol
Low tissue specificity
{'Ciliated cells': '88.1', 'Basal respiratory cells': '497.7', 'Club cells': '467.5', 'Ionocytes': '234.1', 'Mucus glandular cells': '39.8', 'Serous glandular cells': '60.4', 'Gastric mucus-secreting cells': '98.5', 'Proximal enterocytes': '34.9', 'Paneth cells': '43.5', 'Distal enterocytes': '88.6', 'Intestinal goblet cells': '96.1', 'Exocrine glandular cells': '-0.497', 'Basal prostatic cells': '655.7', 'Prostatic glandular cells': '99.4', 'Breast glandular cells': '0.159', 'Breast myoepithelial cells': '-0.111', 'Glandular and luminal cells': '65.9', 'Secretory cells': '81.2', 'Basal keratinocytes': '164.1', 'Suprabasal keratinocytes': '215.9', 'Basal squamous epithelial cells': '336.0', 'Squamous epithelial cells': '504.1', 'Alveolar cells type 1': '-0.098', 'Alveolar cells type 2': '-0.338', 'Salivary duct cells': '115.6', 'Ductal cells': '0.303', 'Hepatocytes': '-0.092', 'Cholangiocytes': '91.6', 'Proximal tubular cells': '-0.126', 'Distal tubular cells': '21.5', 'Collecting duct cells': '60.3', 'Mesothelial cells': '0.107', 'Sertoli cells': '0.469', 'Granulosa cells': '265.7', 'Enteroendocrine cells': '53.3', 'Pancreatic endocrine cells': '103.6', 'Leydig cells': '0.536', 'Excitatory neurons': '2.1', 'Inhibitory neurons': '3.6', 'Cone photoreceptor cells': '96.9', 'Rod photoreceptor cells': '128.4', 'Bipolar cells': '92.2', 'Horizontal cells': '68.6', 'Astrocytes': '129.1', 'Oligodendrocyte precursor cells': '6.6', 'Oligodendrocytes': '5.2', 'Microglial cells': '5.4', 'Muller glia cells': '657.9', 'Schwann cells': '-0.025', 'Spermatogonia': '0.380', 'Spermatocytes': '-0.027', 'Early spermatids': '-0.548', 'Late spermatids': '-0.507', 'Oocytes': '66.9', 'Cytotrophoblasts': '10.1', 'Syncytiotrophoblasts': '16.0', 'Extravillous trophoblasts': '163.0', 'Endothelial cells': '222.6', 'Lymphatic endothelial cells': '104.8', 'Cardiomyocytes': '0.265', 'Skeletal myocytes': '-0.231', 'Smooth muscle cells': '289.7', 'Adipocytes': '338.8', 'Melanocytes': '-0.025', 'Fibroblasts': '218.5', 'Peritubular cells': '0.385', 'Endometrial stromal cells': '103.2', 'Ovarian stromal cells': '311.8', 'Undifferentiated cells': '50.9', 'T-cells': '560.5', 'B-cells': '332.4', 'Plasma cells': '657.1', 'Nk-cells': '716.3', 'Granulocytes': '522.8', 'Monocytes': '490.0', 'Macrophages': '259.6', 'Hofbauer cells': '140.2', 'Kupffer cells': '119.3', 'Dendritic cells': '575.8', 'Langerhans cells': '-0.200', 'Erythroid cells': '0.198', 'Adipocytes (Subcutaneous)': '-0.028', 'Adipocytes (Visceral)': '-0.247', 'Breast glandular cells (progenitors)': '-0.041', 'Adipocytes (Breast)': '0.015', 'Colon enterocytes': '0.063', 'Colon enteroendocrine cells': '0.053', 'Enteric glia cells': '-0.039', 'Mitotic cells (Colon)': '0.143', 'Mitotic cells (Heart)': '0.355', 'Podocytes': '-0.111', 'Ascending Loop of Henle cells': '0.222', 'Intercalated cells': '-0.033', 'Cholangiocyte': '0.168', 'NK-cells (Liver)': '-0.137', 'Respiratory ciliated cells': '-0.045', 'Mitotic cells (Lung)': '-0.049', 'NK-cells (Lung)': '0.109', 'B-cells (Lung)': '0.173', 'Alpha cells': '0.166', 'Beta cells': '0.132', 'Prostate glandular cells': '-0.200', 'Prostate basal glandular cells': '0.282', 'Urothelial cells': '0.462', 'Keratinocyte (other)': '-0.205', 'Keratinocyte (granular)': '-0.412', 'Hair cortex cells': '0.382', 'Inner root sheath cells': '0.386', 'Outer root sheath cells': '0.513', 'Sebaceous gland cells': '0.044', 'Eccrine sweat gland cells': '0.191', 'Adipocytes (Skin)': '0.101', 'Mitotic cells (Skin)': '0.169', 'Parietal cells': '-0.265', 'Chief cells': '-0.231', 'Gastric mucous cells': '-0.022', 'Gastric enteroendocrine cells': '-0.087', 'Mitotic cells (Stomach)': '0.072', 'Parafollicular cells': '-0.017', 'Thyroid glandular cells': '0.291', 'Mitotic cells (Thyroid)': '0.040', 'Adrenal cortex cells': '0.320', 'Adrenal medulla cells': '-0.053', 'Mitotic cells (Adrenal gland)': '-0.074', 'Minor salivary glandular cells': '0.140', 'Minor salivary gland ductal cells': '0.241', 'Minor salivary gland basal cells': '0.315', 'Mitotic cells (Minor salivary gland)': '0.160', 'Adipocytes (Minor salivary gland)': '0.388', 'Somatotropes': '-0.002', 'Lactotropes': '-0.155', 'Gonadotropes': '-0.222', 'Corticotropes': '0.301', 'Thyrotropes': '0.002', 'Undifferentiated cells (Pituitary gland)': '-0.177', 'Mitotic cells (Spleen)': '-0.244', 'Platelets': '-0.093', 'Erythrocytes': '-0.178', 'Hematopoietic stem cells': '0.000', 'B-cells (Spleen)': '0.218', 'NK-cells (Spleen)': '-0.005', 'Amygdala excitatory': '6.6', 'Cerebellar inhibitory': '18.7', 'Cge interneuron': '10.8', 'Deep-layer corticothalamic and 6b': '6.0', 'Deep-layer intratelencephalic': '2.4', 'Deep-layer near-projecting': '2.7', 'Eccentric medium spiny neuron': '6.6', 'Hippocampal ca1-3': '4.1', 'Hippocampal ca4': '5.7', 'Hippocampal dentate gyrus': '13.7', 'Lamp5-lhx6 and chandelier': '8.3', 'Lower rhombic lip': '9.6', 'Mammillary body': '2.0', 'Medium spiny neuron': '4.2', 'Mge interneuron': '3.6', 'Midbrain-derived inhibitory': '4.4', 'Miscellaneous': '3.8', 'Splatter': '9.0', 'Thalamic excitatory': '3.8', 'Upper rhombic lip': '21.9', 'Upper-layer intratelencephalic': '4.2', 'Astrocyte': '315.6', 'Bergmann glia': '121.0', 'Central nervous system macrophage': '45.4', 'Choroid plexus epithelial cell': '26.3', 'Committed oligodendrocyte precursor': '16.5', 'Ependymal cell': '20.0', 'Oligodendrocyte': '17.1', 'Oligodendrocyte precursor cell': '22.6', 'Endothelial cell': '96.1', 'Pericyte': '26.3', 'Vascular associated smooth muscle cell': '20.6', 'Fibroblast': '23.8', 'Leukocyte': '62.5', 'Basophil': '240.3', 'Eosinophil': '51.2', 'Neutrophil': '302.0', 'Classical monocyte': '53.4', 'Non-classical monocyte': '9.0', 'Intermediate monocyte': '77.6', 'T-reg': '364.3', 'GdT-cell': '236.8', 'MAIT T-cell': '621.4', 'Memory CD4 T-cell': '164.2', 'Naive CD4 T-cell': '49.3', 'Memory CD8 T-cell': '141.2', 'Naive CD8 T-cell': '70.5', 'Memory B-cell': '97.7', 'Naive B-cell': '11.5', 'Plasmacytoid DC': '388.9', 'Myeloid DC': '472.3', 'NK-cell': '91.1', 'Total PBMC': '265.5', 'Vd2 gdTCR': '541.8', 'Memory CD4 T-cell Th1\\/Th17': '83.8', 'Memory CD4 T-cell Th17': '129.9', 'Memory CD4 T-cell Th2': '114.7', 'Non-Vd2 gdTCR': '509.2', 'Memory CD4 T-cell Th1': '108.8', 'Memory CD4 T-cell TFH': '137.7', 'Terminal effector memory CD4 T-cell': '260.1', 'Central memory CD8 T-cell': '336.5', 'Effector memory CD8 T-cell': '364.6', 'Terminal effector memory CD8 T-cell': '373.9', 'Non-switched memory B-cell': '164.4', 'Plasmablast': '30.7', 'Switched memory B-cell': '124.7', 'Exhausted memory B-cell': '101.9', 'Progenitor cell': '216.8', 'Memory T-reg': '76.3', 'Naive CD4 T-cell activated': '133.5', 'Naive CD8 T-cell activated': '102.4', 'Naive T-reg': '37.7'}
3LQ9, 7MOP
{'Adipose Tissue': 346.77045681063123, 'Adrenal Gland': 262.70957364341086, 'Bladder': 475.72238095238095, 'Blood': 452.111691065662, 'Blood Vessel': 504.9404644194757, 'Brain': 71.52851135503406, 'Breast': 382.68710239651415, 'Cervix Uteri': 424.0257894736842, 'Colon': 114.07041206675224, 'Esophagus': 253.01822006920415, 'Fallopian Tube': 198.44, 'Heart': 105.58174912891984, 'Kidney': 130.4032584269663, 'Liver': 153.05590265486725, 'Lung': 303.5925259515571, 'Muscle': 172.52644209215444, 'Nerve': 855.2694830371568, 'Ovary': 1121.7011666666667, 'Pancreas': 353.1128475609756, 'Pituitary': 229.00936395759717, 'Prostate': 242.9104897959184, 'Salivary Gland': 258.46802469135804, 'Skin': 311.20008844665557, 'Small Intestine': 135.8199465240642, 'Spleen': 195.22510373443984, 'Stomach': 121.27453203342618, 'Testis': 53.880083102493074, 'Thyroid': 170.61324655436448, 'Uterus': 179.40661971830988, 'Vagina': 817.7158333333333}
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[39.74, 42.52, 40.65, 46.73, 47.35, 42.75, 48.03, 40.3, 33.59, 38.68, 38.93, 36.8, 44.47, 45.5, 44.9, 50.45, 45.17, 44.42, 44.7, 50.68, 39.99, 44.54, 45.78, 43.22, 47.18, 45.54, 38.45, 39.51, 43.33, 40.11, 40.82, 45.57, 39.74, 39.9, 42.23, 41.31, 42.9, 39.13, 40.9, 35.63, 36.7, 29.53, 35.14, 31.13, 38.81, 33.54, 40.15, 35.11, 46.88, 43.65, 36.59, 53.23, 45.8, 63.43, 57.93, 44.54, 60.19, 49.05, 42.25, 57.23, 44.98, 52.07, 45.99, 45.57, 45.36, 45.4, 49.05, 49.86, 46.61, 47.24, 45.31, 49.45, 51.66, 47.86, 47.85, 51.03, 53.62, 56.25, 56.4, 56.66, 57.33, 58.8, 57.56, 63.79, 70.37, 81.06, 87.97, 90.13, 93.12, 93.26, 94.94, 95.95, 96.92, 96.27, 96.47, 97.06, 97.61, 96.8, 95.9, 96.85, 96.54, 95.1, 93.58, 94.96, 92.72, 90.52, 90.33, 88.68, 86.32, 79.95, 78.04, 81.15, 81.03, 85.23, 85.2, 90.44, 93.21, 93.7, 95.24, 94.52, 94.99, 95.17, 96.61, 97.35, 96.29, 96.64, 97.46, 96.86, 95.4, 95.98, 96.56, 95.63, 94.33, 94.26, 94.97, 92.51, 91.55, 94.11, 92.03, 93.64, 94.92, 96.48, 96.64, 96.55, 97.4, 97.71, 98.21, 97.56, 97.78, 95.9, 95.54, 93.5, 86.63, 84.51, 85.84, 88.4, 91.43, 93.46, 94.3, 94.25, 93.59, 95.83, 95.77, 96.65, 96.23, 95.0, 93.05, 95.15, 95.2, 96.61, 96.98, 95.64, 96.5, 96.94, 97.65, 97.82, 98.22, 97.34, 96.88, 94.08, 89.57, 81.98, 68.07, 69.1, 64.22, 64.17, 64.15, 62.16, 64.69, 65.3, 61.48, 62.0, 59.41, 57.45, 52.85, 51.55, 48.44, 48.02, 51.81, 50.15, 46.69, 43.86, 47.5, 50.17, 59.24, 67.03, 82.38, 87.81, 90.63, 93.94, 92.8, 93.04, 93.31, 96.66, 96.78, 97.58, 95.6, 96.36, 94.27, 93.94, 93.0, 87.35, 78.29, 69.81, 63.86, 61.25, 62.95, 63.51, 69.55, 65.47, 64.42, 46.58]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
70.941983
0.570129
2,622
O60260
Q9NZ45
31110043, 33082525, 23503661
UbiNet, UbiBrowser, DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
CISD1
MSLTSSSSVRVEWIAAVTIAAGTAAIGYLAYKRFYVKDHRNKAMINLHIQKDNPKIVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHTKHNEETGDNVGPLIIKKKET
Homo sapiens
Mitochondrion outer membrane
Tissue enhanced (parathyroid)
{'Ciliated cells': '84.1', 'Basal respiratory cells': '298.7', 'Club cells': '126.0', 'Ionocytes': '233.0', 'Mucus glandular cells': '46.0', 'Serous glandular cells': '64.0', 'Gastric mucus-secreting cells': '40.1', 'Proximal enterocytes': '543.8', 'Paneth cells': '126.9', 'Distal enterocytes': '99.9', 'Intestinal goblet cells': '129.8', 'Exocrine glandular cells': '-0.678', 'Basal prostatic cells': '37.5', 'Prostatic glandular cells': '23.3', 'Breast glandular cells': '0.015', 'Breast myoepithelial cells': '0.146', 'Glandular and luminal cells': '51.3', 'Secretory cells': '59.0', 'Basal keratinocytes': '107.6', 'Suprabasal keratinocytes': '109.4', 'Basal squamous epithelial cells': '77.1', 'Squamous epithelial cells': '94.7', 'Alveolar cells type 1': '-0.161', 'Alveolar cells type 2': '-0.070', 'Salivary duct cells': '68.5', 'Ductal cells': '0.628', 'Hepatocytes': '0.436', 'Cholangiocytes': '97.3', 'Proximal tubular cells': '0.304', 'Distal tubular cells': '627.0', 'Collecting duct cells': '116.7', 'Mesothelial cells': '0.328', 'Sertoli cells': '-0.442', 'Granulosa cells': '41.4', 'Enteroendocrine cells': '268.7', 'Pancreatic endocrine cells': '66.2', 'Leydig cells': '-0.412', 'Excitatory neurons': '45.6', 'Inhibitory neurons': '50.9', 'Cone photoreceptor cells': '95.2', 'Rod photoreceptor cells': '40.3', 'Bipolar cells': '69.1', 'Horizontal cells': '63.6', 'Astrocytes': '26.0', 'Oligodendrocyte precursor cells': '34.4', 'Oligodendrocytes': '28.8', 'Microglial cells': '20.6', 'Muller glia cells': '43.5', 'Schwann cells': '0.110', 'Spermatogonia': '-0.229', 'Spermatocytes': '0.075', 'Early spermatids': '0.783', 'Late spermatids': '0.524', 'Oocytes': '97.0', 'Cytotrophoblasts': '188.8', 'Syncytiotrophoblasts': '70.5', 'Extravillous trophoblasts': '67.2', 'Endothelial cells': '54.4', 'Lymphatic endothelial cells': '77.0', 'Cardiomyocytes': '0.773', 'Skeletal myocytes': '0.165', 'Smooth muscle cells': '50.0', 'Adipocytes': '32.5', 'Melanocytes': '0.133', 'Fibroblasts': '52.6', 'Peritubular cells': '-0.317', 'Endometrial stromal cells': '31.4', 'Ovarian stromal cells': '54.1', 'Undifferentiated cells': '151.6', 'T-cells': '24.1', 'B-cells': '24.4', 'Plasma cells': '42.2', 'Nk-cells': '25.7', 'Granulocytes': '16.5', 'Monocytes': '5.2', 'Macrophages': '27.6', 'Hofbauer cells': '59.9', 'Kupffer cells': '38.6', 'Dendritic cells': '16.4', 'Langerhans cells': '0.278', 'Erythroid cells': '-0.038', 'Adipocytes (Subcutaneous)': '-0.335', 'Adipocytes (Visceral)': '-0.308', 'Breast glandular cells (progenitors)': '-0.016', 'Adipocytes (Breast)': '-0.227', 'Colon enterocytes': '-0.191', 'Colon enteroendocrine cells': '0.202', 'Enteric glia cells': '-0.019', 'Mitotic cells (Colon)': '-0.040', 'Mitotic cells (Heart)': '0.424', 'Podocytes': '0.160', 'Ascending Loop of Henle cells': '0.380', 'Intercalated cells': '0.206', 'Cholangiocyte': '0.401', 'NK-cells (Liver)': '-0.365', 'Respiratory ciliated cells': '-0.063', 'Mitotic cells (Lung)': '0.166', 'NK-cells (Lung)': '-0.054', 'B-cells (Lung)': '-0.065', 'Alpha cells': '0.383', 'Beta cells': '0.221', 'Prostate glandular cells': '-0.389', 'Prostate basal glandular cells': '-0.068', 'Urothelial cells': '-0.028', 'Keratinocyte (other)': '0.275', 'Keratinocyte (granular)': '-0.158', 'Hair cortex cells': '-0.137', 'Inner root sheath cells': '-0.070', 'Outer root sheath cells': '0.149', 'Sebaceous gland cells': '0.172', 'Eccrine sweat gland cells': '0.025', 'Adipocytes (Skin)': '-0.140', 'Mitotic cells (Skin)': '0.384', 'Parietal cells': '-0.497', 'Chief cells': '-0.539', 'Gastric mucous cells': '-0.364', 'Gastric enteroendocrine cells': '-0.454', 'Mitotic cells (Stomach)': '0.079', 'Parafollicular cells': '0.065', 'Thyroid glandular cells': '0.273', 'Mitotic cells (Thyroid)': '0.027', 'Adrenal cortex cells': '0.498', 'Adrenal medulla cells': '0.109', 'Mitotic cells (Adrenal gland)': '0.411', 'Minor salivary glandular cells': '0.334', 'Minor salivary gland ductal cells': '-0.133', 'Minor salivary gland basal cells': '0.391', 'Mitotic cells (Minor salivary gland)': '0.585', 'Adipocytes (Minor salivary gland)': '0.182', 'Somatotropes': '0.250', 'Lactotropes': '0.272', 'Gonadotropes': '-0.019', 'Corticotropes': '0.333', 'Thyrotropes': '0.287', 'Undifferentiated cells (Pituitary gland)': '-0.205', 'Mitotic cells (Spleen)': '-0.095', 'Platelets': '-0.167', 'Erythrocytes': '-0.128', 'Hematopoietic stem cells': '-0.187', 'B-cells (Spleen)': '0.050', 'NK-cells (Spleen)': '0.145', 'Amygdala excitatory': '62.0', 'Cerebellar inhibitory': '119.1', 'Cge interneuron': '74.9', 'Deep-layer corticothalamic and 6b': '66.8', 'Deep-layer intratelencephalic': '65.5', 'Deep-layer near-projecting': '65.2', 'Eccentric medium spiny neuron': '58.8', 'Hippocampal ca1-3': '66.6', 'Hippocampal ca4': '107.4', 'Hippocampal dentate gyrus': '76.3', 'Lamp5-lhx6 and chandelier': '83.3', 'Lower rhombic lip': '122.4', 'Mammillary body': '104.3', 'Medium spiny neuron': '74.8', 'Mge interneuron': '88.9', 'Midbrain-derived inhibitory': '107.0', 'Miscellaneous': '67.0', 'Splatter': '101.5', 'Thalamic excitatory': '82.7', 'Upper rhombic lip': '84.4', 'Upper-layer intratelencephalic': '61.9', 'Astrocyte': '42.2', 'Bergmann glia': '39.8', 'Central nervous system macrophage': '23.1', 'Choroid plexus epithelial cell': '109.9', 'Committed oligodendrocyte precursor': '40.2', 'Ependymal cell': '36.5', 'Oligodendrocyte': '42.3', 'Oligodendrocyte precursor cell': '49.7', 'Endothelial cell': '43.0', 'Pericyte': '48.9', 'Vascular associated smooth muscle cell': '31.8', 'Fibroblast': '49.6', 'Leukocyte': '18.6', 'Basophil': '0.0', 'Eosinophil': '0.2', 'Neutrophil': '0.8', 'Classical monocyte': '3.1', 'Non-classical monocyte': '2.3', 'Intermediate monocyte': '1.3', 'T-reg': '3.4', 'GdT-cell': '4.3', 'MAIT T-cell': '3.8', 'Memory CD4 T-cell': '4.9', 'Naive CD4 T-cell': '6.8', 'Memory CD8 T-cell': '5.0', 'Naive CD8 T-cell': '6.4', 'Memory B-cell': '6.4', 'Naive B-cell': '3.5', 'Plasmacytoid DC': '1.9', 'Myeloid DC': '6.3', 'NK-cell': '6.6', 'Total PBMC': '2.5', 'Vd2 gdTCR': '3.9', 'Memory CD4 T-cell Th1\\/Th17': '6.3', 'Memory CD4 T-cell Th17': '5.9', 'Memory CD4 T-cell Th2': '6.0', 'Non-Vd2 gdTCR': '2.6', 'Memory CD4 T-cell Th1': '5.2', 'Memory CD4 T-cell TFH': '5.8', 'Terminal effector memory CD4 T-cell': '4.4', 'Central memory CD8 T-cell': '3.4', 'Effector memory CD8 T-cell': '4.2', 'Terminal effector memory CD8 T-cell': '2.3', 'Non-switched memory B-cell': '3.9', 'Plasmablast': '6.2', 'Switched memory B-cell': '4.1', 'Exhausted memory B-cell': '2.7', 'Progenitor cell': '2.3', 'Memory T-reg': '6.2', 'Naive CD4 T-cell activated': '35.6', 'Naive CD8 T-cell activated': '31.8', 'Naive T-reg': '8.3'}
2QD0, 2QH7, 2R13, 3EW0, 3LPQ, 3REE, 4EZF, 4F1E, 4F28, 4F2C, 6DE9, 7P0O
{'Adipose Tissue': 11.679972591362128, 'Adrenal Gland': 16.673705426356587, 'Bladder': 21.72533333333333, 'Blood': 5.602682346609257, 'Blood Vessel': 16.124203745318354, 'Brain': 22.89365632096896, 'Breast': 9.876795206971677, 'Cervix Uteri': 12.36515789473684, 'Colon': 20.458346598202823, 'Esophagus': 20.65851141868512, 'Fallopian Tube': 11.582555555555556, 'Heart': 27.6777574912892, 'Kidney': 19.58056179775281, 'Liver': 9.574203539823008, 'Lung': 11.96167474048443, 'Muscle': 30.312987546699876, 'Nerve': 9.20267366720517, 'Ovary': 12.849833333333333, 'Pancreas': 3.964146341463415, 'Pituitary': 22.62868197879859, 'Prostate': 12.09710612244898, 'Salivary Gland': 11.271845679012346, 'Skin': 13.083161415146488, 'Small Intestine': 18.027171122994652, 'Spleen': 9.446066390041494, 'Stomach': 12.1613286908078, 'Testis': 15.411731301939058, 'Thyroid': 15.379211332312403, 'Uterus': 12.57712676056338, 'Vagina': 10.860057692307691}
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[54.39, 60.12, 60.32, 63.04, 73.38, 78.28, 81.19, 82.73, 86.44, 88.54, 90.29, 89.47, 93.8, 92.84, 93.22, 93.81, 95.21, 95.34, 95.97, 96.01, 96.57, 96.73, 97.02, 97.2, 97.14, 97.16, 96.82, 96.21, 95.86, 94.76, 93.89, 92.84, 88.34, 88.96, 86.23, 81.53, 69.85, 67.97, 60.41, 57.48, 64.34, 78.35, 85.63, 91.29, 93.99, 95.7, 94.31, 94.94, 97.08, 96.08, 96.49, 97.19, 96.99, 97.06, 97.13, 97.32, 96.97, 96.14, 95.46, 93.76, 93.83, 88.29, 88.21, 90.28, 88.57, 89.17, 92.69, 94.24, 95.52, 97.66, 98.05, 98.45, 97.71, 97.54, 97.84, 97.67, 98.26, 97.61, 97.42, 98.26, 97.36, 97.87, 98.42, 98.12, 98.16, 98.45, 98.19, 98.45, 98.37, 97.39, 98.27, 98.46, 97.81, 95.77, 96.5, 96.26, 97.64, 97.68, 98.25, 98.38, 97.71, 96.82, 95.29, 93.82, 91.43, 89.08, 85.73, 83.62]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
91.297685
0.559444
2,975
O60260
Q9P2E9
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
RRBP1
MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHDPAPNVTVLLREPVRAPAVAVAPTPVQPPIIVAPVATVPAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLTSKAAILETAPKEVPMVVVPPVGAKGNTPATGTTQGKKAEGTQNQSKKAEGAPNQGRKAEGTPNQGKKTEGTPNQGKKAEGTPNQGKKAEGTPNQGKKAEGAQNQGKKVDTTPNQGKKVEGAPTQGRKAEGAQNQAKKVEGAQNQGKKAEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGQKGEGAQNQGKKTEGAQGKKAERSPNQGKKGEGAPIQGKKADSVANQGTKVEGITNQGKKAEGSPSEGKKAEGSPNQGKKADAAANQGKKTESASVQGRNTDVAQSPEAPKQEAPAKKKSGSKKKGEPGPPDADGPLYLPYKTLVSTVGSMVFNEGEAQRLIEILSEKAGIIQDTWHKATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLEWTEAILEDEQTQRQKLTAEFEEAQTSACRLQEELEKLRTAGPLESSETEEASQLKERLEKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTVKKLQEQLEKAEDGSSSKEGTSV
Homo sapiens
Endoplasmic reticulum membrane
Tissue enhanced (pancreas)
{'Ciliated cells': '100.0', 'Basal respiratory cells': '90.5', 'Club cells': '160.7', 'Ionocytes': '130.7', 'Mucus glandular cells': '313.2', 'Serous glandular cells': '507.5', 'Gastric mucus-secreting cells': '254.1', 'Proximal enterocytes': '217.4', 'Paneth cells': '274.1', 'Distal enterocytes': '502.7', 'Intestinal goblet cells': '385.3', 'Exocrine glandular cells': '0.044', 'Basal prostatic cells': '162.6', 'Prostatic glandular cells': '145.3', 'Breast glandular cells': '0.455', 'Breast myoepithelial cells': '0.470', 'Glandular and luminal cells': '311.1', 'Secretory cells': '157.1', 'Basal keratinocytes': '72.8', 'Suprabasal keratinocytes': '93.7', 'Basal squamous epithelial cells': '57.2', 'Squamous epithelial cells': '72.5', 'Alveolar cells type 1': '-0.122', 'Alveolar cells type 2': '-0.036', 'Salivary duct cells': '174.5', 'Ductal cells': '0.084', 'Hepatocytes': '0.310', 'Cholangiocytes': '154.5', 'Proximal tubular cells': '0.178', 'Distal tubular cells': '21.5', 'Collecting duct cells': '97.2', 'Mesothelial cells': '0.170', 'Sertoli cells': '0.455', 'Granulosa cells': '64.4', 'Enteroendocrine cells': '142.7', 'Pancreatic endocrine cells': '124.0', 'Leydig cells': '0.443', 'Excitatory neurons': '2.9', 'Inhibitory neurons': '4.6', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '34.2', 'Bipolar cells': '17.1', 'Horizontal cells': '35.3', 'Astrocytes': '14.2', 'Oligodendrocyte precursor cells': '21.7', 'Oligodendrocytes': '25.7', 'Microglial cells': '17.0', 'Muller glia cells': '124.7', 'Schwann cells': '0.000', 'Spermatogonia': '0.597', 'Spermatocytes': '0.291', 'Early spermatids': '-0.417', 'Late spermatids': '-0.492', 'Oocytes': '39.7', 'Cytotrophoblasts': '261.8', 'Syncytiotrophoblasts': '563.9', 'Extravillous trophoblasts': '265.8', 'Endothelial cells': '162.1', 'Lymphatic endothelial cells': '153.5', 'Cardiomyocytes': '0.153', 'Skeletal myocytes': '0.008', 'Smooth muscle cells': '132.8', 'Adipocytes': '146.1', 'Melanocytes': '0.105', 'Fibroblasts': '225.8', 'Peritubular cells': '0.416', 'Endometrial stromal cells': '228.2', 'Ovarian stromal cells': '111.5', 'Undifferentiated cells': '157.1', 'T-cells': '50.1', 'B-cells': '33.9', 'Plasma cells': '586.9', 'Nk-cells': '120.3', 'Granulocytes': '94.4', 'Monocytes': '207.1', 'Macrophages': '108.9', 'Hofbauer cells': '99.3', 'Kupffer cells': '57.4', 'Dendritic cells': '719.5', 'Langerhans cells': '0.046', 'Erythroid cells': '-0.081', 'Adipocytes (Subcutaneous)': '-0.213', 'Adipocytes (Visceral)': '-0.209', 'Breast glandular cells (progenitors)': '0.282', 'Adipocytes (Breast)': '-0.544', 'Colon enterocytes': '0.182', 'Colon enteroendocrine cells': '0.030', 'Enteric glia cells': '0.199', 'Mitotic cells (Colon)': '0.387', 'Mitotic cells (Heart)': '0.451', 'Podocytes': '-0.204', 'Ascending Loop of Henle cells': '0.291', 'Intercalated cells': '-0.230', 'Cholangiocyte': '0.309', 'NK-cells (Liver)': '-0.309', 'Respiratory ciliated cells': '-0.073', 'Mitotic cells (Lung)': '0.085', 'NK-cells (Lung)': '0.116', 'B-cells (Lung)': '0.050', 'Alpha cells': '0.107', 'Beta cells': '0.040', 'Prostate glandular cells': '0.119', 'Prostate basal glandular cells': '0.175', 'Urothelial cells': '0.205', 'Keratinocyte (other)': '-0.155', 'Keratinocyte (granular)': '-0.380', 'Hair cortex cells': '0.316', 'Inner root sheath cells': '0.311', 'Outer root sheath cells': '0.453', 'Sebaceous gland cells': '0.056', 'Eccrine sweat gland cells': '0.270', 'Adipocytes (Skin)': '0.064', 'Mitotic cells (Skin)': '0.141', 'Parietal cells': '0.328', 'Chief cells': '0.562', 'Gastric mucous cells': '0.572', 'Gastric enteroendocrine cells': '0.512', 'Mitotic cells (Stomach)': '0.434', 'Parafollicular cells': '0.188', 'Thyroid glandular cells': '0.525', 'Mitotic cells (Thyroid)': '-0.025', 'Adrenal cortex cells': '0.485', 'Adrenal medulla cells': '-0.029', 'Mitotic cells (Adrenal gland)': '0.027', 'Minor salivary glandular cells': '0.593', 'Minor salivary gland ductal cells': '0.222', 'Minor salivary gland basal cells': '-0.347', 'Mitotic cells (Minor salivary gland)': '-0.377', 'Adipocytes (Minor salivary gland)': '-0.242', 'Somatotropes': '-0.055', 'Lactotropes': '-0.055', 'Gonadotropes': '0.124', 'Corticotropes': '0.013', 'Thyrotropes': '0.185', 'Undifferentiated cells (Pituitary gland)': '0.091', 'Mitotic cells (Spleen)': '0.363', 'Platelets': '0.017', 'Erythrocytes': '0.181', 'Hematopoietic stem cells': '-0.023', 'B-cells (Spleen)': '-0.278', 'NK-cells (Spleen)': '-0.171', 'Amygdala excitatory': '5.4', 'Cerebellar inhibitory': '34.4', 'Cge interneuron': '9.6', 'Deep-layer corticothalamic and 6b': '4.3', 'Deep-layer intratelencephalic': '8.7', 'Deep-layer near-projecting': '11.2', 'Eccentric medium spiny neuron': '5.4', 'Hippocampal ca1-3': '5.0', 'Hippocampal ca4': '7.1', 'Hippocampal dentate gyrus': '4.1', 'Lamp5-lhx6 and chandelier': '9.4', 'Lower rhombic lip': '5.1', 'Mammillary body': '5.9', 'Medium spiny neuron': '5.3', 'Mge interneuron': '8.1', 'Midbrain-derived inhibitory': '4.5', 'Miscellaneous': '5.4', 'Splatter': '9.8', 'Thalamic excitatory': '6.6', 'Upper rhombic lip': '14.4', 'Upper-layer intratelencephalic': '5.9', 'Astrocyte': '34.1', 'Bergmann glia': '19.5', 'Central nervous system macrophage': '66.0', 'Choroid plexus epithelial cell': '62.3', 'Committed oligodendrocyte precursor': '133.2', 'Ependymal cell': '18.5', 'Oligodendrocyte': '68.1', 'Oligodendrocyte precursor cell': '64.7', 'Endothelial cell': '48.7', 'Pericyte': '20.8', 'Vascular associated smooth muscle cell': '31.1', 'Fibroblast': '86.6', 'Leukocyte': '49.5', 'Basophil': '11.0', 'Eosinophil': '38.6', 'Neutrophil': '11.1', 'Classical monocyte': '33.0', 'Non-classical monocyte': '39.4', 'Intermediate monocyte': '16.6', 'T-reg': '3.8', 'GdT-cell': '4.2', 'MAIT T-cell': '9.1', 'Memory CD4 T-cell': '1.4', 'Naive CD4 T-cell': '11.6', 'Memory CD8 T-cell': '2.6', 'Naive CD8 T-cell': '11.3', 'Memory B-cell': '1.0', 'Naive B-cell': '16.7', 'Plasmacytoid DC': '81.2', 'Myeloid DC': '25.8', 'NK-cell': '62.3', 'Total PBMC': '12.6', 'Vd2 gdTCR': '10.8', 'Memory CD4 T-cell Th1\\/Th17': '20.2', 'Memory CD4 T-cell Th17': '20.8', 'Memory CD4 T-cell Th2': '22.0', 'Non-Vd2 gdTCR': '14.1', 'Memory CD4 T-cell Th1': '28.2', 'Memory CD4 T-cell TFH': '23.5', 'Terminal effector memory CD4 T-cell': '13.3', 'Central memory CD8 T-cell': '5.9', 'Effector memory CD8 T-cell': '10.9', 'Terminal effector memory CD8 T-cell': '15.0', 'Non-switched memory B-cell': '7.3', 'Plasmablast': '109.2', 'Switched memory B-cell': '4.5', 'Exhausted memory B-cell': '7.7', 'Progenitor cell': '9.7', 'Memory T-reg': '26.3', 'Naive CD4 T-cell activated': '7.6', 'Naive CD8 T-cell activated': '11.3', 'Naive T-reg': '13.8'}
null
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0.49, 0.56, 0.22, 0.37, 0.51, 0.42, 0.18, 0.54, 0.53, 0.15, 0.42, 0.38, 0.5, 0.3, 0.53, 0.65, 0.6, 0.71, 0.62, 0.51, 0.66, 0.64, 0.72, 0.84, 0.9, 0.72, 0.82, 1.0, 0.72]
null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
68.21878
0.559475
229
O60260
Q9UBC2
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
EPS15L1
MAAPLIPLSQQIPTGNSLYESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVTLSNLNLSMPPPKFHDTSSPLMVTPPSAEAHWAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSALPPSLIPPSKRKKTVFPGAVPVLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSLKQTQPTVNWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKDQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPGPDSSGSLGSGEFTGVKELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSLAERGSFGAMDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKGADPFKGDPFQNDPFAEQQTTSTDPFGGDPFKESDPFRGSATDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSVSSKGSDPFGTLDPFGSGSFNSAEGFADFSQMSKPPPSGPFTSSLGGAGFSDDPFKSKQDTPALPPKKPAPPRPKPPSGKSTPVSQLGSADFPEAPDPFQPLGADSGDPFQSKKGFGDPFSGKDPFVPSSAAKPSKASASGFADFTSVS
Homo sapiens
Cell membrane, Nucleus, Membrane, coated pit
Low tissue specificity
{'Ciliated cells': '13.6', 'Basal respiratory cells': '11.6', 'Club cells': '11.7', 'Ionocytes': '15.1', 'Mucus glandular cells': '11.3', 'Serous glandular cells': '13.1', 'Gastric mucus-secreting cells': '15.3', 'Proximal enterocytes': '7.3', 'Paneth cells': '9.0', 'Distal enterocytes': '13.5', 'Intestinal goblet cells': '8.9', 'Exocrine glandular cells': '-0.699', 'Basal prostatic cells': '10.4', 'Prostatic glandular cells': '12.7', 'Breast glandular cells': '0.505', 'Breast myoepithelial cells': '0.501', 'Glandular and luminal cells': '11.0', 'Secretory cells': '9.4', 'Basal keratinocytes': '17.8', 'Suprabasal keratinocytes': '27.0', 'Basal squamous epithelial cells': '13.3', 'Squamous epithelial cells': '21.7', 'Alveolar cells type 1': '0.137', 'Alveolar cells type 2': '-0.420', 'Salivary duct cells': '10.9', 'Ductal cells': '0.523', 'Hepatocytes': '0.082', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.313', 'Distal tubular cells': '0.0', 'Collecting duct cells': '7.8', 'Mesothelial cells': '0.440', 'Sertoli cells': '-0.056', 'Granulosa cells': '14.9', 'Enteroendocrine cells': '5.9', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '-0.056', 'Excitatory neurons': '48.0', 'Inhibitory neurons': '60.8', 'Cone photoreceptor cells': '25.5', 'Rod photoreceptor cells': '30.5', 'Bipolar cells': '27.7', 'Horizontal cells': '34.0', 'Astrocytes': '59.1', 'Oligodendrocyte precursor cells': '34.0', 'Oligodendrocytes': '33.1', 'Microglial cells': '29.5', 'Muller glia cells': '9.9', 'Schwann cells': '0.055', 'Spermatogonia': '0.167', 'Spermatocytes': '0.325', 'Early spermatids': '0.148', 'Late spermatids': '0.012', 'Oocytes': '22.8', 'Cytotrophoblasts': '21.8', 'Syncytiotrophoblasts': '11.1', 'Extravillous trophoblasts': '19.0', 'Endothelial cells': '11.0', 'Lymphatic endothelial cells': '18.6', 'Cardiomyocytes': '0.752', 'Skeletal myocytes': '-0.320', 'Smooth muscle cells': '13.2', 'Adipocytes': '9.9', 'Melanocytes': '0.266', 'Fibroblasts': '14.6', 'Peritubular cells': '0.120', 'Endometrial stromal cells': '11.6', 'Ovarian stromal cells': '18.7', 'Undifferentiated cells': '8.9', 'T-cells': '16.3', 'B-cells': '21.9', 'Plasma cells': '14.9', 'Nk-cells': '31.5', 'Granulocytes': '13.5', 'Monocytes': '11.9', 'Macrophages': '11.6', 'Hofbauer cells': '17.8', 'Kupffer cells': '9.7', 'Dendritic cells': '32.0', 'Langerhans cells': '0.321', 'Erythroid cells': '0.115', 'Adipocytes (Subcutaneous)': '-0.395', 'Adipocytes (Visceral)': '-0.330', 'Breast glandular cells (progenitors)': '0.369', 'Adipocytes (Breast)': '-0.475', 'Colon enterocytes': '-0.189', 'Colon enteroendocrine cells': '0.239', 'Enteric glia cells': '0.116', 'Mitotic cells (Colon)': '-0.240', 'Mitotic cells (Heart)': '0.441', 'Podocytes': '0.034', 'Ascending Loop of Henle cells': '0.422', 'Intercalated cells': '0.076', 'Cholangiocyte': '0.307', 'NK-cells (Liver)': '-0.195', 'Respiratory ciliated cells': '0.090', 'Mitotic cells (Lung)': '-0.122', 'NK-cells (Lung)': '0.330', 'B-cells (Lung)': '0.063', 'Alpha cells': '0.376', 'Beta cells': '0.219', 'Prostate glandular cells': '-0.247', 'Prostate basal glandular cells': '-0.095', 'Urothelial cells': '-0.002', 'Keratinocyte (other)': '0.670', 'Keratinocyte (granular)': '0.124', 'Hair cortex cells': '-0.247', 'Inner root sheath cells': '-0.202', 'Outer root sheath cells': '-0.097', 'Sebaceous gland cells': '-0.193', 'Eccrine sweat gland cells': '-0.339', 'Adipocytes (Skin)': '-0.482', 'Mitotic cells (Skin)': '0.294', 'Parietal cells': '-0.663', 'Chief cells': '-0.627', 'Gastric mucous cells': '-0.323', 'Gastric enteroendocrine cells': '-0.481', 'Mitotic cells (Stomach)': '0.069', 'Parafollicular cells': '0.100', 'Thyroid glandular cells': '0.421', 'Mitotic cells (Thyroid)': '-0.007', 'Adrenal cortex cells': '0.292', 'Adrenal medulla cells': '-0.032', 'Mitotic cells (Adrenal gland)': '0.108', 'Minor salivary glandular cells': '0.155', 'Minor salivary gland ductal cells': '-0.264', 'Minor salivary gland basal cells': '0.628', 'Mitotic cells (Minor salivary gland)': '0.693', 'Adipocytes (Minor salivary gland)': '0.273', 'Somatotropes': '0.023', 'Lactotropes': '0.195', 'Gonadotropes': '0.126', 'Corticotropes': '0.344', 'Thyrotropes': '0.225', 'Undifferentiated cells (Pituitary gland)': '-0.069', 'Mitotic cells (Spleen)': '-0.201', 'Platelets': '-0.161', 'Erythrocytes': '0.024', 'Hematopoietic stem cells': '-0.267', 'B-cells (Spleen)': '0.459', 'NK-cells (Spleen)': '0.363', 'Amygdala excitatory': '97.2', 'Cerebellar inhibitory': '89.7', 'Cge interneuron': '96.7', 'Deep-layer corticothalamic and 6b': '107.5', 'Deep-layer intratelencephalic': '100.5', 'Deep-layer near-projecting': '77.5', 'Eccentric medium spiny neuron': '76.2', 'Hippocampal ca1-3': '91.9', 'Hippocampal ca4': '121.0', 'Hippocampal dentate gyrus': '154.4', 'Lamp5-lhx6 and chandelier': '92.2', 'Lower rhombic lip': '80.5', 'Mammillary body': '104.4', 'Medium spiny neuron': '68.6', 'Mge interneuron': '98.1', 'Midbrain-derived inhibitory': '100.6', 'Miscellaneous': '76.3', 'Splatter': '84.1', 'Thalamic excitatory': '114.1', 'Upper rhombic lip': '82.3', 'Upper-layer intratelencephalic': '93.8', 'Astrocyte': '185.3', 'Bergmann glia': '121.0', 'Central nervous system macrophage': '99.4', 'Choroid plexus epithelial cell': '73.1', 'Committed oligodendrocyte precursor': '70.7', 'Ependymal cell': '85.9', 'Oligodendrocyte': '63.8', 'Oligodendrocyte precursor cell': '66.8', 'Endothelial cell': '64.6', 'Pericyte': '90.4', 'Vascular associated smooth muscle cell': '52.9', 'Fibroblast': '85.1', 'Leukocyte': '76.5', 'Basophil': '237.5', 'Eosinophil': '36.0', 'Neutrophil': '194.8', 'Classical monocyte': '21.2', 'Non-classical monocyte': '22.9', 'Intermediate monocyte': '46.4', 'T-reg': '40.9', 'GdT-cell': '11.2', 'MAIT T-cell': '59.2', 'Memory CD4 T-cell': '9.8', 'Naive CD4 T-cell': '20.6', 'Memory CD8 T-cell': '12.0', 'Naive CD8 T-cell': '19.3', 'Memory B-cell': '20.9', 'Naive B-cell': '29.4', 'Plasmacytoid DC': '48.3', 'Myeloid DC': '40.3', 'NK-cell': '45.0', 'Total PBMC': '46.3', 'Vd2 gdTCR': '46.5', 'Memory CD4 T-cell Th1\\/Th17': '20.7', 'Memory CD4 T-cell Th17': '23.5', 'Memory CD4 T-cell Th2': '24.8', 'Non-Vd2 gdTCR': '61.0', 'Memory CD4 T-cell Th1': '25.1', 'Memory CD4 T-cell TFH': '27.6', 'Terminal effector memory CD4 T-cell': '56.2', 'Central memory CD8 T-cell': '39.7', 'Effector memory CD8 T-cell': '53.8', 'Terminal effector memory CD8 T-cell': '51.7', 'Non-switched memory B-cell': '84.6', 'Plasmablast': '29.5', 'Switched memory B-cell': '100.4', 'Exhausted memory B-cell': '76.4', 'Progenitor cell': '70.8', 'Memory T-reg': '27.6', 'Naive CD4 T-cell activated': '21.3', 'Naive CD8 T-cell activated': '23.5', 'Naive T-reg': '22.1'}
null
{'Adipose Tissue': 12.855660299003322, 'Adrenal Gland': 9.816806201550389, 'Bladder': 16.416190476190476, 'Blood': 16.812754359526373, 'Blood Vessel': 15.079314606741573, 'Brain': 12.96980393641181, 'Breast': 12.9071568627451, 'Cervix Uteri': 21.498947368421053, 'Colon': 13.064957637997434, 'Esophagus': 15.147835294117646, 'Fallopian Tube': 19.816666666666663, 'Heart': 13.786372009291522, 'Kidney': 8.631, 'Liver': 3.884907079646018, 'Lung': 14.54771626297578, 'Muscle': 29.82014570361146, 'Nerve': 17.95507269789984, 'Ovary': 19.92194444444444, 'Pancreas': 4.3629542682926825, 'Pituitary': 17.130102473498233, 'Prostate': 14.977534693877551, 'Salivary Gland': 10.333413580246914, 'Skin': 17.386723051409618, 'Small Intestine': 11.10475935828877, 'Spleen': 13.251597510373443, 'Stomach': 10.001261838440112, 'Testis': 18.104736842105265, 'Thyroid': 17.04826339969372, 'Uterus': 21.19232394366197, 'Vagina': 18.16794871794872}
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37.4, 39.38, 40.96, 37.67, 39.52, 46.65, 37.86, 36.8, 39.16, 39.03, 38.86, 38.77, 37.28, 37.46, 38.82, 35.39, 38.71, 41.09, 43.4, 42.33, 41.83, 47.8, 40.68, 35.5, 41.38, 38.94, 45.49, 36.87, 46.46, 42.72, 35.34, 42.52, 36.18, 36.71, 37.17, 35.0, 36.37, 35.26, 33.06, 39.36, 34.12, 39.97, 38.21, 45.22, 45.01, 52.55, 49.04, 42.39, 42.54, 43.69, 37.82, 41.0, 52.42, 48.03, 44.11, 50.96, 64.56, 57.9, 48.37, 58.24, 59.34, 54.72, 64.5, 68.64, 52.97, 58.67, 60.34, 60.79, 54.89, 52.62, 43.76, 45.34, 43.53, 40.75, 39.55, 40.81, 39.91, 39.57, 40.15, 37.6, 39.23, 41.72, 39.47, 43.69, 48.11, 43.05, 44.68, 48.43, 46.63, 47.68, 47.75, 48.09, 42.23, 38.42, 39.32, 38.52, 40.85, 44.92, 39.6, 43.04, 47.02, 42.77, 40.2, 40.08, 40.15, 42.59, 39.35, 43.91, 40.63, 40.4, 52.53, 42.6, 40.19, 43.38, 44.46, 48.28, 52.52, 45.48, 45.73, 38.9, 38.68, 40.32, 42.8, 42.21, 45.96, 45.89, 43.24, 40.91, 42.5, 43.55, 45.76, 49.65, 43.36, 51.89, 47.17, 44.37, 44.0, 49.66, 50.88, 54.15, 44.18]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
66.353414
0.650579
703
O60260
Q9UH62
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
ARMCX3
MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGSGDVDDAGDCSGARYNDWSDDDDDSNESKSIVWYPPWARIGTEAGTRARARARARATRARRAVQKRASPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDPIVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEYQHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKENKEVILKLLVIFENINDNFKWEENEPTQNQFGEGSLFFFLKEFQVCADKVLGIESHHDFLVKVKVGKFMAKLAEHMFPKSQE
Homo sapiens
Mitochondrion outer membrane, Cytoplasm, Nucleus
Low tissue specificity
{'Ciliated cells': '30.2', 'Basal respiratory cells': '39.3', 'Club cells': '59.3', 'Ionocytes': '38.7', 'Mucus glandular cells': '64.6', 'Serous glandular cells': '86.4', 'Gastric mucus-secreting cells': '30.1', 'Proximal enterocytes': '20.2', 'Paneth cells': '28.2', 'Distal enterocytes': '17.5', 'Intestinal goblet cells': '55.2', 'Exocrine glandular cells': '-0.536', 'Basal prostatic cells': '108.4', 'Prostatic glandular cells': '88.1', 'Breast glandular cells': '0.539', 'Breast myoepithelial cells': '0.632', 'Glandular and luminal cells': '81.8', 'Secretory cells': '53.9', 'Basal keratinocytes': '24.9', 'Suprabasal keratinocytes': '12.8', 'Basal squamous epithelial cells': '34.1', 'Squamous epithelial cells': '22.0', 'Alveolar cells type 1': '0.089', 'Alveolar cells type 2': '-0.495', 'Salivary duct cells': '52.8', 'Ductal cells': '0.463', 'Hepatocytes': '0.399', 'Cholangiocytes': '45.8', 'Proximal tubular cells': '0.162', 'Distal tubular cells': '36.9', 'Collecting duct cells': '62.2', 'Mesothelial cells': '0.458', 'Sertoli cells': '0.681', 'Granulosa cells': '45.4', 'Enteroendocrine cells': '45.9', 'Pancreatic endocrine cells': '54.3', 'Leydig cells': '0.682', 'Excitatory neurons': '34.7', 'Inhibitory neurons': '40.1', 'Cone photoreceptor cells': '44.2', 'Rod photoreceptor cells': '14.0', 'Bipolar cells': '55.7', 'Horizontal cells': '75.5', 'Astrocytes': '15.5', 'Oligodendrocyte precursor cells': '26.9', 'Oligodendrocytes': '28.8', 'Microglial cells': '17.9', 'Muller glia cells': '88.9', 'Schwann cells': '0.059', 'Spermatogonia': '0.447', 'Spermatocytes': '0.015', 'Early spermatids': '-0.570', 'Late spermatids': '-0.747', 'Oocytes': '1.5', 'Cytotrophoblasts': '54.1', 'Syncytiotrophoblasts': '133.8', 'Extravillous trophoblasts': '30.7', 'Endothelial cells': '61.4', 'Lymphatic endothelial cells': '57.8', 'Cardiomyocytes': '0.668', 'Skeletal myocytes': '0.113', 'Smooth muscle cells': '73.1', 'Adipocytes': '65.5', 'Melanocytes': '-0.079', 'Fibroblasts': '77.8', 'Peritubular cells': '0.576', 'Endometrial stromal cells': '79.8', 'Ovarian stromal cells': '69.6', 'Undifferentiated cells': '28.8', 'T-cells': '56.4', 'B-cells': '51.1', 'Plasma cells': '122.8', 'Nk-cells': '59.7', 'Granulocytes': '154.4', 'Monocytes': '65.3', 'Macrophages': '63.2', 'Hofbauer cells': '49.6', 'Kupffer cells': '51.4', 'Dendritic cells': '96.5', 'Langerhans cells': '0.005', 'Erythroid cells': '-0.013', 'Adipocytes (Subcutaneous)': '-0.378', 'Adipocytes (Visceral)': '-0.417', 'Breast glandular cells (progenitors)': '0.342', 'Adipocytes (Breast)': '-0.529', 'Colon enterocytes': '-0.216', 'Colon enteroendocrine cells': '0.346', 'Enteric glia cells': '0.178', 'Mitotic cells (Colon)': '-0.036', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '0.079', 'Ascending Loop of Henle cells': '0.494', 'Intercalated cells': '0.144', 'Cholangiocyte': '0.366', 'NK-cells (Liver)': '-0.295', 'Respiratory ciliated cells': '0.027', 'Mitotic cells (Lung)': '-0.004', 'NK-cells (Lung)': '0.486', 'B-cells (Lung)': '0.250', 'Alpha cells': '0.336', 'Beta cells': '0.200', 'Prostate glandular cells': '0.217', 'Prostate basal glandular cells': '0.071', 'Urothelial cells': '-0.058', 'Keratinocyte (other)': '-0.392', 'Keratinocyte (granular)': '-0.442', 'Hair cortex cells': '0.305', 'Inner root sheath cells': '0.324', 'Outer root sheath cells': '0.542', 'Sebaceous gland cells': '0.115', 'Eccrine sweat gland cells': '0.579', 'Adipocytes (Skin)': '0.338', 'Mitotic cells (Skin)': '0.236', 'Parietal cells': '-0.659', 'Chief cells': '-0.406', 'Gastric mucous cells': '-0.515', 'Gastric enteroendocrine cells': '-0.365', 'Mitotic cells (Stomach)': '-0.095', 'Parafollicular cells': '0.171', 'Thyroid glandular cells': '0.569', 'Mitotic cells (Thyroid)': '0.089', 'Adrenal cortex cells': '0.606', 'Adrenal medulla cells': '0.127', 'Mitotic cells (Adrenal gland)': '0.200', 'Minor salivary glandular cells': '0.289', 'Minor salivary gland ductal cells': '0.340', 'Minor salivary gland basal cells': '-0.257', 'Mitotic cells (Minor salivary gland)': '-0.220', 'Adipocytes (Minor salivary gland)': '-0.036', 'Somatotropes': '0.394', 'Lactotropes': '0.199', 'Gonadotropes': '0.162', 'Corticotropes': '-0.011', 'Thyrotropes': '0.200', 'Undifferentiated cells (Pituitary gland)': '-0.099', 'Mitotic cells (Spleen)': '-0.176', 'Platelets': '-0.190', 'Erythrocytes': '-0.101', 'Hematopoietic stem cells': '-0.178', 'B-cells (Spleen)': '0.118', 'NK-cells (Spleen)': '0.277', 'Amygdala excitatory': '28.5', 'Cerebellar inhibitory': '46.4', 'Cge interneuron': '45.6', 'Deep-layer corticothalamic and 6b': '36.3', 'Deep-layer intratelencephalic': '34.9', 'Deep-layer near-projecting': '43.4', 'Eccentric medium spiny neuron': '42.1', 'Hippocampal ca1-3': '43.0', 'Hippocampal ca4': '42.7', 'Hippocampal dentate gyrus': '35.6', 'Lamp5-lhx6 and chandelier': '57.0', 'Lower rhombic lip': '55.6', 'Mammillary body': '63.8', 'Medium spiny neuron': '37.2', 'Mge interneuron': '58.4', 'Midbrain-derived inhibitory': '61.9', 'Miscellaneous': '45.4', 'Splatter': '42.3', 'Thalamic excitatory': '49.8', 'Upper rhombic lip': '39.9', 'Upper-layer intratelencephalic': '33.6', 'Astrocyte': '22.3', 'Bergmann glia': '27.2', 'Central nervous system macrophage': '29.0', 'Choroid plexus epithelial cell': '32.3', 'Committed oligodendrocyte precursor': '41.5', 'Ependymal cell': '20.4', 'Oligodendrocyte': '36.2', 'Oligodendrocyte precursor cell': '47.8', 'Endothelial cell': '39.1', 'Pericyte': '28.0', 'Vascular associated smooth muscle cell': '40.0', 'Fibroblast': '22.8', 'Leukocyte': '25.4', 'Basophil': '69.7', 'Eosinophil': '13.6', 'Neutrophil': '28.2', 'Classical monocyte': '21.0', 'Non-classical monocyte': '24.5', 'Intermediate monocyte': '42.2', 'T-reg': '39.9', 'GdT-cell': '14.7', 'MAIT T-cell': '51.2', 'Memory CD4 T-cell': '14.1', 'Naive CD4 T-cell': '38.0', 'Memory CD8 T-cell': '12.4', 'Naive CD8 T-cell': '32.2', 'Memory B-cell': '15.1', 'Naive B-cell': '48.0', 'Plasmacytoid DC': '88.4', 'Myeloid DC': '44.4', 'NK-cell': '32.8', 'Total PBMC': '42.2', 'Vd2 gdTCR': '51.7', 'Memory CD4 T-cell Th1\\/Th17': '31.1', 'Memory CD4 T-cell Th17': '27.4', 'Memory CD4 T-cell Th2': '33.8', 'Non-Vd2 gdTCR': '43.4', 'Memory CD4 T-cell Th1': '25.4', 'Memory CD4 T-cell TFH': '32.7', 'Terminal effector memory CD4 T-cell': '42.8', 'Central memory CD8 T-cell': '55.9', 'Effector memory CD8 T-cell': '47.8', 'Terminal effector memory CD8 T-cell': '45.3', 'Non-switched memory B-cell': '51.3', 'Plasmablast': '156.3', 'Switched memory B-cell': '50.8', 'Exhausted memory B-cell': '38.0', 'Progenitor cell': '61.1', 'Memory T-reg': '21.3', 'Naive CD4 T-cell activated': '50.1', 'Naive CD8 T-cell activated': '40.9', 'Naive T-reg': '38.9'}
null
{'Adipose Tissue': 47.285736710963455, 'Adrenal Gland': 71.72302325581396, 'Bladder': 48.567142857142855, 'Blood': 15.733393433799783, 'Blood Vessel': 60.12245692883895, 'Brain': 38.790319454958365, 'Breast': 48.006470588235295, 'Cervix Uteri': 68.04947368421053, 'Colon': 42.741255455712455, 'Esophagus': 34.625539100346025, 'Fallopian Tube': 56.67666666666667, 'Heart': 27.24121138211382, 'Kidney': 28.43559550561798, 'Liver': 15.721685840707964, 'Lung': 54.81112456747405, 'Muscle': 19.426714819427147, 'Nerve': 60.5086914378029, 'Ovary': 73.74111111111111, 'Pancreas': 34.027378048780484, 'Pituitary': 84.59780918727915, 'Prostate': 49.133469387755106, 'Salivary Gland': 45.715333333333334, 'Skin': 32.23344112769486, 'Small Intestine': 32.88357219251337, 'Spleen': 52.99161825726141, 'Stomach': 35.60896935933148, 'Testis': 23.166110803324106, 'Thyroid': 63.430199081163856, 'Uterus': 69.64894366197183, 'Vagina': 43.01846153846154}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
76.394222
0.43058
1,756
O60260
Q9UHQ9
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
CYB5R1
MGIQTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVSHNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYSQKMRFTY
Homo sapiens
Membrane
Tissue enhanced (skeletal)
{'Ciliated cells': '70.1', 'Basal respiratory cells': '84.4', 'Club cells': '52.5', 'Ionocytes': '79.9', 'Mucus glandular cells': '30.2', 'Serous glandular cells': '56.3', 'Gastric mucus-secreting cells': '33.6', 'Proximal enterocytes': '15.1', 'Paneth cells': '10.3', 'Distal enterocytes': '12.0', 'Intestinal goblet cells': '9.7', 'Exocrine glandular cells': '-0.612', 'Basal prostatic cells': '22.6', 'Prostatic glandular cells': '26.9', 'Breast glandular cells': '0.612', 'Breast myoepithelial cells': '0.480', 'Glandular and luminal cells': '36.1', 'Secretory cells': '27.2', 'Basal keratinocytes': '121.8', 'Suprabasal keratinocytes': '112.7', 'Basal squamous epithelial cells': '35.5', 'Squamous epithelial cells': '40.8', 'Alveolar cells type 1': '0.086', 'Alveolar cells type 2': '0.325', 'Salivary duct cells': '21.4', 'Ductal cells': '0.439', 'Hepatocytes': '0.578', 'Cholangiocytes': '38.2', 'Proximal tubular cells': '0.259', 'Distal tubular cells': '6.1', 'Collecting duct cells': '29.2', 'Mesothelial cells': '0.285', 'Sertoli cells': '0.825', 'Granulosa cells': '15.4', 'Enteroendocrine cells': '20.1', 'Pancreatic endocrine cells': '32.3', 'Leydig cells': '0.482', 'Excitatory neurons': '8.6', 'Inhibitory neurons': '10.8', 'Cone photoreceptor cells': '47.6', 'Rod photoreceptor cells': '30.0', 'Bipolar cells': '19.9', 'Horizontal cells': '20.1', 'Astrocytes': '9.6', 'Oligodendrocyte precursor cells': '10.8', 'Oligodendrocytes': '7.6', 'Microglial cells': '8.1', 'Muller glia cells': '54.7', 'Schwann cells': '0.155', 'Spermatogonia': '0.414', 'Spermatocytes': '0.108', 'Early spermatids': '-0.420', 'Late spermatids': '-0.610', 'Oocytes': '3.7', 'Cytotrophoblasts': '170.0', 'Syncytiotrophoblasts': '330.6', 'Extravillous trophoblasts': '224.4', 'Endothelial cells': '28.8', 'Lymphatic endothelial cells': '31.3', 'Cardiomyocytes': '0.697', 'Skeletal myocytes': '0.284', 'Smooth muscle cells': '32.6', 'Adipocytes': '32.9', 'Melanocytes': '0.200', 'Fibroblasts': '32.8', 'Peritubular cells': '0.452', 'Endometrial stromal cells': '17.1', 'Ovarian stromal cells': '44.4', 'Undifferentiated cells': '15.2', 'T-cells': '19.0', 'B-cells': '14.6', 'Plasma cells': '20.5', 'Nk-cells': '9.8', 'Granulocytes': '29.5', 'Monocytes': '15.2', 'Macrophages': '32.5', 'Hofbauer cells': '52.7', 'Kupffer cells': '39.0', 'Dendritic cells': '10.4', 'Langerhans cells': '0.291', 'Erythroid cells': '-0.046', 'Adipocytes (Subcutaneous)': '0.127', 'Adipocytes (Visceral)': '0.101', 'Breast glandular cells (progenitors)': '0.349', 'Adipocytes (Breast)': '-0.479', 'Colon enterocytes': '-0.158', 'Colon enteroendocrine cells': '0.368', 'Enteric glia cells': '0.079', 'Mitotic cells (Colon)': '-0.250', 'Mitotic cells (Heart)': '0.424', 'Podocytes': '-0.128', 'Ascending Loop of Henle cells': '0.546', 'Intercalated cells': '0.033', 'Cholangiocyte': '0.300', 'NK-cells (Liver)': '-0.255', 'Respiratory ciliated cells': '0.070', 'Mitotic cells (Lung)': '0.170', 'NK-cells (Lung)': '-0.199', 'B-cells (Lung)': '-0.264', 'Alpha cells': '0.400', 'Beta cells': '0.205', 'Prostate glandular cells': '0.016', 'Prostate basal glandular cells': '0.162', 'Urothelial cells': '-0.005', 'Keratinocyte (other)': '0.783', 'Keratinocyte (granular)': '0.190', 'Hair cortex cells': '-0.401', 'Inner root sheath cells': '-0.392', 'Outer root sheath cells': '-0.306', 'Sebaceous gland cells': '-0.151', 'Eccrine sweat gland cells': '-0.445', 'Adipocytes (Skin)': '-0.540', 'Mitotic cells (Skin)': '0.210', 'Parietal cells': '0.773', 'Chief cells': '0.537', 'Gastric mucous cells': '0.596', 'Gastric enteroendocrine cells': '0.447', 'Mitotic cells (Stomach)': '0.208', 'Parafollicular cells': '0.131', 'Thyroid glandular cells': '0.613', 'Mitotic cells (Thyroid)': '-0.037', 'Adrenal cortex cells': '0.604', 'Adrenal medulla cells': '0.145', 'Mitotic cells (Adrenal gland)': '0.416', 'Minor salivary glandular cells': '0.283', 'Minor salivary gland ductal cells': '-0.195', 'Minor salivary gland basal cells': '0.219', 'Mitotic cells (Minor salivary gland)': '0.413', 'Adipocytes (Minor salivary gland)': '0.061', 'Somatotropes': '-0.108', 'Lactotropes': '0.128', 'Gonadotropes': '0.181', 'Corticotropes': '0.466', 'Thyrotropes': '0.443', 'Undifferentiated cells (Pituitary gland)': '-0.014', 'Mitotic cells (Spleen)': '-0.397', 'Platelets': '0.091', 'Erythrocytes': '-0.232', 'Hematopoietic stem cells': '-0.082', 'B-cells (Spleen)': '0.174', 'NK-cells (Spleen)': '0.175', 'Amygdala excitatory': '11.7', 'Cerebellar inhibitory': '13.9', 'Cge interneuron': '19.2', 'Deep-layer corticothalamic and 6b': '16.2', 'Deep-layer intratelencephalic': '14.0', 'Deep-layer near-projecting': '16.7', 'Eccentric medium spiny neuron': '11.5', 'Hippocampal ca1-3': '20.0', 'Hippocampal ca4': '20.6', 'Hippocampal dentate gyrus': '13.3', 'Lamp5-lhx6 and chandelier': '23.2', 'Lower rhombic lip': '18.0', 'Mammillary body': '20.5', 'Medium spiny neuron': '12.0', 'Mge interneuron': '17.1', 'Midbrain-derived inhibitory': '15.5', 'Miscellaneous': '14.7', 'Splatter': '18.9', 'Thalamic excitatory': '19.6', 'Upper rhombic lip': '9.4', 'Upper-layer intratelencephalic': '10.3', 'Astrocyte': '18.6', 'Bergmann glia': '14.6', 'Central nervous system macrophage': '20.4', 'Choroid plexus epithelial cell': '14.4', 'Committed oligodendrocyte precursor': '16.0', 'Ependymal cell': '43.6', 'Oligodendrocyte': '13.1', 'Oligodendrocyte precursor cell': '14.0', 'Endothelial cell': '13.5', 'Pericyte': '20.4', 'Vascular associated smooth muscle cell': '14.9', 'Fibroblast': '14.7', 'Leukocyte': '10.9', 'Basophil': '33.8', 'Eosinophil': '46.7', 'Neutrophil': '84.9', 'Classical monocyte': '31.6', 'Non-classical monocyte': '15.1', 'Intermediate monocyte': '54.6', 'T-reg': '51.5', 'GdT-cell': '27.4', 'MAIT T-cell': '50.9', 'Memory CD4 T-cell': '31.0', 'Naive CD4 T-cell': '33.3', 'Memory CD8 T-cell': '28.9', 'Naive CD8 T-cell': '29.4', 'Memory B-cell': '23.5', 'Naive B-cell': '23.5', 'Plasmacytoid DC': '67.4', 'Myeloid DC': '72.6', 'NK-cell': '20.5', 'Total PBMC': '82.5', 'Vd2 gdTCR': '49.8', 'Memory CD4 T-cell Th1\\/Th17': '27.4', 'Memory CD4 T-cell Th17': '30.3', 'Memory CD4 T-cell Th2': '29.4', 'Non-Vd2 gdTCR': '36.6', 'Memory CD4 T-cell Th1': '30.8', 'Memory CD4 T-cell TFH': '33.5', 'Terminal effector memory CD4 T-cell': '50.1', 'Central memory CD8 T-cell': '57.0', 'Effector memory CD8 T-cell': '36.8', 'Terminal effector memory CD8 T-cell': '45.6', 'Non-switched memory B-cell': '52.3', 'Plasmablast': '41.1', 'Switched memory B-cell': '37.4', 'Exhausted memory B-cell': '39.2', 'Progenitor cell': '48.1', 'Memory T-reg': '26.9', 'Naive CD4 T-cell activated': '23.1', 'Naive CD8 T-cell activated': '26.2', 'Naive T-reg': '31.9'}
null
{'Adipose Tissue': 27.773828903654486, 'Adrenal Gland': 34.030720930232555, 'Bladder': 46.92142857142857, 'Blood': 16.729564047362754, 'Blood Vessel': 44.13088389513109, 'Brain': 15.261419379258138, 'Breast': 33.52875816993464, 'Cervix Uteri': 46.54842105263158, 'Colon': 23.590779204107832, 'Esophagus': 33.803641522491354, 'Fallopian Tube': 44.06111111111111, 'Heart': 35.57940534262485, 'Kidney': 19.549191011235955, 'Liver': 13.659446902654867, 'Lung': 36.08262975778546, 'Muscle': 179.88331257783312, 'Nerve': 40.82988691437803, 'Ovary': 38.69155555555555, 'Pancreas': 12.91424695121951, 'Pituitary': 42.29809187279152, 'Prostate': 32.809551020408165, 'Salivary Gland': 37.17703703703704, 'Skin': 69.68760088446655, 'Small Intestine': 20.372620320855617, 'Spleen': 31.156514522821578, 'Stomach': 48.268830083565454, 'Testis': 53.86418282548477, 'Thyroid': 34.99987748851454, 'Uterus': 41.01859154929578, 'Vagina': 41.63166666666667}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
94.410852
0.349377
2,251
O60260
Q9UNE7
22199232, UNIPROT
UbiNet, UbiBrowser, 31181401
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
STUB1
MKGKEEKEGGARLGAGGGSPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLSRLIAAERERELEECQRNHEGDEDDSHVRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWVEDY
Homo sapiens
Cytoplasm, Nucleus, Mitochondrion
Low tissue specificity
{'Ciliated cells': '111.1', 'Basal respiratory cells': '59.2', 'Club cells': '101.1', 'Ionocytes': '46.0', 'Mucus glandular cells': '86.7', 'Serous glandular cells': '148.1', 'Gastric mucus-secreting cells': '70.2', 'Proximal enterocytes': '167.9', 'Paneth cells': '98.7', 'Distal enterocytes': '138.9', 'Intestinal goblet cells': '87.5', 'Exocrine glandular cells': '-0.531', 'Basal prostatic cells': '118.1', 'Prostatic glandular cells': '121.3', 'Breast glandular cells': '0.097', 'Breast myoepithelial cells': '-0.087', 'Glandular and luminal cells': '74.9', 'Secretory cells': '138.4', 'Basal keratinocytes': '120.7', 'Suprabasal keratinocytes': '182.5', 'Basal squamous epithelial cells': '84.4', 'Squamous epithelial cells': '109.7', 'Alveolar cells type 1': '0.126', 'Alveolar cells type 2': '-0.059', 'Salivary duct cells': '84.8', 'Ductal cells': '0.303', 'Hepatocytes': '0.273', 'Cholangiocytes': '99.2', 'Proximal tubular cells': '0.250', 'Distal tubular cells': '169.0', 'Collecting duct cells': '132.2', 'Mesothelial cells': '0.155', 'Sertoli cells': '0.652', 'Granulosa cells': '88.1', 'Enteroendocrine cells': '93.6', 'Pancreatic endocrine cells': '124.0', 'Leydig cells': '0.576', 'Excitatory neurons': '22.4', 'Inhibitory neurons': '20.3', 'Cone photoreceptor cells': '112.1', 'Rod photoreceptor cells': '67.6', 'Bipolar cells': '85.7', 'Horizontal cells': '56.7', 'Astrocytes': '23.2', 'Oligodendrocyte precursor cells': '13.2', 'Oligodendrocytes': '23.1', 'Microglial cells': '14.3', 'Muller glia cells': '173.3', 'Schwann cells': '-0.012', 'Spermatogonia': '0.377', 'Spermatocytes': '0.041', 'Early spermatids': '-0.555', 'Late spermatids': '-0.642', 'Oocytes': '96.3', 'Cytotrophoblasts': '82.7', 'Syncytiotrophoblasts': '102.9', 'Extravillous trophoblasts': '101.3', 'Endothelial cells': '73.3', 'Lymphatic endothelial cells': '81.3', 'Cardiomyocytes': '0.682', 'Skeletal myocytes': '-0.006', 'Smooth muscle cells': '115.9', 'Adipocytes': '95.5', 'Melanocytes': '0.048', 'Fibroblasts': '103.7', 'Peritubular cells': '0.476', 'Endometrial stromal cells': '74.2', 'Ovarian stromal cells': '122.8', 'Undifferentiated cells': '95.2', 'T-cells': '97.0', 'B-cells': '81.4', 'Plasma cells': '126.4', 'Nk-cells': '101.5', 'Granulocytes': '128.9', 'Monocytes': '67.2', 'Macrophages': '80.1', 'Hofbauer cells': '115.8', 'Kupffer cells': '59.0', 'Dendritic cells': '66.3', 'Langerhans cells': '0.178', 'Erythroid cells': '0.008', 'Adipocytes (Subcutaneous)': '0.370', 'Adipocytes (Visceral)': '0.363', 'Breast glandular cells (progenitors)': '0.015', 'Adipocytes (Breast)': '0.193', 'Colon enterocytes': '-0.214', 'Colon enteroendocrine cells': '0.182', 'Enteric glia cells': '0.066', 'Mitotic cells (Colon)': '-0.386', 'Mitotic cells (Heart)': '0.434', 'Podocytes': '0.010', 'Ascending Loop of Henle cells': '0.432', 'Intercalated cells': '0.060', 'Cholangiocyte': '0.319', 'NK-cells (Liver)': '-0.223', 'Respiratory ciliated cells': '0.028', 'Mitotic cells (Lung)': '-0.077', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.166', 'Alpha cells': '0.326', 'Beta cells': '0.218', 'Prostate glandular cells': '0.082', 'Prostate basal glandular cells': '0.140', 'Urothelial cells': '0.026', 'Keratinocyte (other)': '0.374', 'Keratinocyte (granular)': '0.501', 'Hair cortex cells': '-0.170', 'Inner root sheath cells': '-0.239', 'Outer root sheath cells': '-0.285', 'Sebaceous gland cells': '-0.138', 'Eccrine sweat gland cells': '-0.455', 'Adipocytes (Skin)': '-0.312', 'Mitotic cells (Skin)': '-0.117', 'Parietal cells': '-0.632', 'Chief cells': '-0.412', 'Gastric mucous cells': '-0.492', 'Gastric enteroendocrine cells': '-0.411', 'Mitotic cells (Stomach)': '-0.132', 'Parafollicular cells': '0.093', 'Thyroid glandular cells': '0.398', 'Mitotic cells (Thyroid)': '-0.082', 'Adrenal cortex cells': '0.387', 'Adrenal medulla cells': '0.044', 'Mitotic cells (Adrenal gland)': '0.250', 'Minor salivary glandular cells': '0.181', 'Minor salivary gland ductal cells': '-0.090', 'Minor salivary gland basal cells': '0.208', 'Mitotic cells (Minor salivary gland)': '0.120', 'Adipocytes (Minor salivary gland)': '0.058', 'Somatotropes': '0.056', 'Lactotropes': '0.089', 'Gonadotropes': '-0.139', 'Corticotropes': '0.184', 'Thyrotropes': '0.212', 'Undifferentiated cells (Pituitary gland)': '0.045', 'Mitotic cells (Spleen)': '-0.379', 'Platelets': '-0.139', 'Erythrocytes': '-0.088', 'Hematopoietic stem cells': '-0.293', 'B-cells (Spleen)': '0.307', 'NK-cells (Spleen)': '0.247', 'Amygdala excitatory': '18.1', 'Cerebellar inhibitory': '38.8', 'Cge interneuron': '39.7', 'Deep-layer corticothalamic and 6b': '30.5', 'Deep-layer intratelencephalic': '31.1', 'Deep-layer near-projecting': '35.7', 'Eccentric medium spiny neuron': '22.2', 'Hippocampal ca1-3': '25.7', 'Hippocampal ca4': '44.6', 'Hippocampal dentate gyrus': '30.0', 'Lamp5-lhx6 and chandelier': '37.7', 'Lower rhombic lip': '61.9', 'Mammillary body': '24.7', 'Medium spiny neuron': '18.1', 'Mge interneuron': '31.4', 'Midbrain-derived inhibitory': '38.4', 'Miscellaneous': '34.4', 'Splatter': '36.4', 'Thalamic excitatory': '48.8', 'Upper rhombic lip': '47.7', 'Upper-layer intratelencephalic': '29.3', 'Astrocyte': '29.5', 'Bergmann glia': '48.0', 'Central nervous system macrophage': '21.6', 'Choroid plexus epithelial cell': '25.5', 'Committed oligodendrocyte precursor': '30.9', 'Ependymal cell': '36.1', 'Oligodendrocyte': '39.2', 'Oligodendrocyte precursor cell': '26.0', 'Endothelial cell': '33.2', 'Pericyte': '60.3', 'Vascular associated smooth muscle cell': '50.0', 'Fibroblast': '25.6', 'Leukocyte': '36.8', 'Basophil': '10.0', 'Eosinophil': '21.7', 'Neutrophil': '19.2', 'Classical monocyte': '7.5', 'Non-classical monocyte': '5.6', 'Intermediate monocyte': '16.3', 'T-reg': '17.6', 'GdT-cell': '15.8', 'MAIT T-cell': '24.4', 'Memory CD4 T-cell': '13.5', 'Naive CD4 T-cell': '6.6', 'Memory CD8 T-cell': '13.8', 'Naive CD8 T-cell': '10.5', 'Memory B-cell': '19.7', 'Naive B-cell': '5.3', 'Plasmacytoid DC': '22.5', 'Myeloid DC': '21.8', 'NK-cell': '14.0', 'Total PBMC': '22.4', 'Vd2 gdTCR': '27.3', 'Memory CD4 T-cell Th1\\/Th17': '8.4', 'Memory CD4 T-cell Th17': '13.4', 'Memory CD4 T-cell Th2': '13.3', 'Non-Vd2 gdTCR': '19.6', 'Memory CD4 T-cell Th1': '15.2', 'Memory CD4 T-cell TFH': '20.5', 'Terminal effector memory CD4 T-cell': '13.3', 'Central memory CD8 T-cell': '13.8', 'Effector memory CD8 T-cell': '20.2', 'Terminal effector memory CD8 T-cell': '24.2', 'Non-switched memory B-cell': '16.4', 'Plasmablast': '33.0', 'Switched memory B-cell': '20.8', 'Exhausted memory B-cell': '19.3', 'Progenitor cell': '10.2', 'Memory T-reg': '18.4', 'Naive CD4 T-cell activated': '5.5', 'Naive CD8 T-cell activated': '7.7', 'Naive T-reg': '11.0'}
4KBQ, 6EFK, 6NSV, 7TB1, 8EHZ, 8EI0, 8F14, 8F15, 8F16, 8F17, 8FYU, 8GCK, 8SUV
{'Adipose Tissue': 78.61480897009966, 'Adrenal Gland': 92.7037984496124, 'Bladder': 87.96000000000001, 'Blood': 35.57494833153929, 'Blood Vessel': 107.46397752808988, 'Brain': 85.27770628311886, 'Breast': 80.3040522875817, 'Cervix Uteri': 94.52684210526316, 'Colon': 82.91942233632864, 'Esophagus': 84.54604152249135, 'Fallopian Tube': 90.65555555555557, 'Heart': 48.65891521486643, 'Kidney': 52.94651685393258, 'Liver': 33.70513274336283, 'Lung': 78.17375432525952, 'Muscle': 90.29261519302617, 'Nerve': 100.68132471728596, 'Ovary': 83.62011111111111, 'Pancreas': 35.99783536585366, 'Pituitary': 94.97544169611308, 'Prostate': 84.82922448979592, 'Salivary Gland': 66.96043209876544, 'Skin': 107.44185185185184, 'Small Intestine': 62.40716577540107, 'Spleen': 69.39991701244814, 'Stomach': 67.49392757660166, 'Testis': 60.49448753462603, 'Thyroid': 91.81369065849924, 'Uterus': 96.53704225352112, 'Vagina': 82.03814102564102}
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[41.83, 42.93, 41.86, 49.52, 46.6, 38.82, 48.64, 36.57, 41.3, 38.41, 42.01, 42.11, 40.22, 41.96, 47.24, 36.91, 36.28, 40.65, 43.9, 48.06, 52.57, 67.43, 79.85, 84.86, 92.16, 92.78, 92.88, 94.44, 95.1, 94.33, 95.9, 95.26, 96.38, 96.16, 97.05, 96.79, 96.61, 96.38, 96.35, 94.46, 96.84, 96.79, 96.67, 96.16, 97.15, 97.17, 96.48, 95.67, 96.92, 96.95, 95.86, 95.71, 96.34, 95.64, 93.7, 92.99, 94.54, 95.23, 94.88, 96.17, 95.87, 96.69, 97.74, 97.03, 96.67, 97.17, 97.01, 96.05, 96.95, 97.35, 94.89, 94.75, 94.95, 93.7, 95.26, 94.87, 95.29, 95.49, 96.7, 96.28, 96.74, 97.06, 97.12, 96.7, 96.65, 97.03, 96.51, 96.73, 96.48, 94.49, 94.84, 95.01, 95.21, 95.89, 95.39, 96.78, 97.05, 96.54, 96.15, 96.7, 96.21, 95.29, 95.53, 96.19, 94.6, 93.81, 94.0, 93.84, 95.2, 94.04, 94.31, 95.78, 96.28, 95.15, 96.42, 96.66, 96.17, 95.48, 95.6, 95.8, 93.93, 94.73, 95.49, 94.38, 91.49, 94.47, 94.18, 92.99, 92.61, 89.98, 88.2, 87.06, 88.21, 90.56, 91.87, 90.47, 89.45, 92.7, 92.03, 87.56, 89.97, 93.2, 90.28, 88.97, 91.04, 92.58, 87.73, 89.65, 91.63, 90.47, 88.88, 90.65, 93.8, 91.54, 91.26, 94.74, 95.17, 93.89, 93.73, 97.21, 97.16, 96.43, 96.96, 97.9, 97.12, 96.89, 97.69, 97.6, 96.54, 95.97, 97.09, 96.31, 95.55, 95.51, 95.62, 94.0, 92.8, 92.03, 91.65, 89.06, 86.45, 88.06, 85.39, 81.01, 72.44, 72.02, 67.28, 60.3, 71.45, 80.06, 83.14, 83.6, 84.7, 87.62, 90.0, 89.01, 91.38, 93.57, 94.2, 93.44, 94.95, 96.07, 96.72, 96.61, 96.46, 97.11, 96.75, 95.85, 96.97, 96.81, 95.9, 95.53, 95.95, 95.07, 94.22, 92.4, 92.85, 89.5, 86.64, 86.56, 84.18, 80.51, 75.75, 76.05, 81.74, 82.47, 87.9, 92.12, 90.95, 93.9, 94.51, 93.14, 92.51, 92.58, 91.33, 88.91, 88.76, 90.35, 92.34, 93.96, 90.73, 93.98, 97.36, 97.2, 97.54, 96.89, 96.58, 95.23, 95.68, 96.27, 97.36, 96.85, 96.39, 95.23, 93.29, 95.07, 95.9, 95.44, 94.76, 95.07, 95.98, 94.44, 95.01, 94.52, 94.0, 96.14, 96.17, 95.53, 94.73, 94.62, 95.85, 94.24, 95.46, 96.45, 96.43, 94.59, 93.6, 94.81, 95.51, 96.53, 96.93, 97.25, 96.99, 96.47, 97.13, 96.39, 95.9, 95.85, 96.14, 94.16, 91.99, 93.6, 92.86, 89.39, 86.76, 86.6, 86.8, 79.8, 83.6, 83.36, 71.56, 68.03, 56.23]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
89.311584
0.412772
2,372
O60260
Q9UNM6
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
PSMD13
MKDVPGFLQQSQNSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDVKSMEMLVEHQAHDILT
Homo sapiens
null
Low tissue specificity
{'Ciliated cells': '50.9', 'Basal respiratory cells': '122.7', 'Club cells': '61.8', 'Ionocytes': '78.8', 'Mucus glandular cells': '34.0', 'Serous glandular cells': '50.5', 'Gastric mucus-secreting cells': '25.9', 'Proximal enterocytes': '80.5', 'Paneth cells': '65.8', 'Distal enterocytes': '75.6', 'Intestinal goblet cells': '64.5', 'Exocrine glandular cells': '-0.742', 'Basal prostatic cells': '48.6', 'Prostatic glandular cells': '59.5', 'Breast glandular cells': '0.323', 'Breast myoepithelial cells': '0.246', 'Glandular and luminal cells': '49.2', 'Secretory cells': '62.3', 'Basal keratinocytes': '52.5', 'Suprabasal keratinocytes': '64.9', 'Basal squamous epithelial cells': '25.3', 'Squamous epithelial cells': '34.4', 'Alveolar cells type 1': '-0.066', 'Alveolar cells type 2': '-0.127', 'Salivary duct cells': '34.7', 'Ductal cells': '0.537', 'Hepatocytes': '0.403', 'Cholangiocytes': '43.9', 'Proximal tubular cells': '0.155', 'Distal tubular cells': '67.6', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.198', 'Sertoli cells': '0.397', 'Granulosa cells': '47.7', 'Enteroendocrine cells': '56.2', 'Pancreatic endocrine cells': '125.6', 'Leydig cells': '0.340', 'Excitatory neurons': '16.2', 'Inhibitory neurons': '14.9', 'Cone photoreceptor cells': '45.9', 'Rod photoreceptor cells': '36.9', 'Bipolar cells': '40.5', 'Horizontal cells': '34.6', 'Astrocytes': '16.1', 'Oligodendrocyte precursor cells': '8.0', 'Oligodendrocytes': '16.0', 'Microglial cells': '10.7', 'Muller glia cells': '60.3', 'Schwann cells': '0.002', 'Spermatogonia': '0.462', 'Spermatocytes': '0.382', 'Early spermatids': '-0.019', 'Late spermatids': '-0.324', 'Oocytes': '77.9', 'Cytotrophoblasts': '165.6', 'Syncytiotrophoblasts': '221.8', 'Extravillous trophoblasts': '149.6', 'Endothelial cells': '68.8', 'Lymphatic endothelial cells': '61.1', 'Cardiomyocytes': '0.672', 'Skeletal myocytes': '-0.330', 'Smooth muscle cells': '59.9', 'Adipocytes': '72.9', 'Melanocytes': '0.316', 'Fibroblasts': '64.4', 'Peritubular cells': '0.178', 'Endometrial stromal cells': '47.9', 'Ovarian stromal cells': '56.6', 'Undifferentiated cells': '78.6', 'T-cells': '71.2', 'B-cells': '57.7', 'Plasma cells': '88.3', 'Nk-cells': '85.6', 'Granulocytes': '72.5', 'Monocytes': '78.1', 'Macrophages': '62.4', 'Hofbauer cells': '102.0', 'Kupffer cells': '41.0', 'Dendritic cells': '44.7', 'Langerhans cells': '0.194', 'Erythroid cells': '-0.061', 'Adipocytes (Subcutaneous)': '-0.049', 'Adipocytes (Visceral)': '-0.200', 'Breast glandular cells (progenitors)': '0.097', 'Adipocytes (Breast)': '-0.256', 'Colon enterocytes': '-0.213', 'Colon enteroendocrine cells': '0.152', 'Enteric glia cells': '-0.080', 'Mitotic cells (Colon)': '-0.068', 'Mitotic cells (Heart)': '0.518', 'Podocytes': '-0.070', 'Ascending Loop of Henle cells': '0.425', 'Intercalated cells': '-0.026', 'Cholangiocyte': '0.363', 'NK-cells (Liver)': '-0.406', 'Respiratory ciliated cells': '-0.041', 'Mitotic cells (Lung)': '0.079', 'NK-cells (Lung)': '0.121', 'B-cells (Lung)': '-0.093', 'Alpha cells': '0.384', 'Beta cells': '0.203', 'Prostate glandular cells': '0.398', 'Prostate basal glandular cells': '0.341', 'Urothelial cells': '0.024', 'Keratinocyte (other)': '0.232', 'Keratinocyte (granular)': '-0.006', 'Hair cortex cells': '0.099', 'Inner root sheath cells': '0.146', 'Outer root sheath cells': '0.082', 'Sebaceous gland cells': '-0.045', 'Eccrine sweat gland cells': '-0.333', 'Adipocytes (Skin)': '-0.185', 'Mitotic cells (Skin)': '0.243', 'Parietal cells': '-0.646', 'Chief cells': '-0.512', 'Gastric mucous cells': '-0.243', 'Gastric enteroendocrine cells': '-0.389', 'Mitotic cells (Stomach)': '0.204', 'Parafollicular cells': '0.086', 'Thyroid glandular cells': '0.236', 'Mitotic cells (Thyroid)': '0.018', 'Adrenal cortex cells': '0.457', 'Adrenal medulla cells': '0.065', 'Mitotic cells (Adrenal gland)': '0.244', 'Minor salivary glandular cells': '0.421', 'Minor salivary gland ductal cells': '-0.151', 'Minor salivary gland basal cells': '0.480', 'Mitotic cells (Minor salivary gland)': '0.535', 'Adipocytes (Minor salivary gland)': '0.222', 'Somatotropes': '0.100', 'Lactotropes': '0.114', 'Gonadotropes': '0.027', 'Corticotropes': '0.072', 'Thyrotropes': '0.101', 'Undifferentiated cells (Pituitary gland)': '-0.033', 'Mitotic cells (Spleen)': '-0.125', 'Platelets': '-0.028', 'Erythrocytes': '-0.038', 'Hematopoietic stem cells': '-0.083', 'B-cells (Spleen)': '0.272', 'NK-cells (Spleen)': '0.086', 'Amygdala excitatory': '26.1', 'Cerebellar inhibitory': '35.4', 'Cge interneuron': '24.1', 'Deep-layer corticothalamic and 6b': '29.3', 'Deep-layer intratelencephalic': '28.5', 'Deep-layer near-projecting': '26.6', 'Eccentric medium spiny neuron': '25.6', 'Hippocampal ca1-3': '29.1', 'Hippocampal ca4': '38.8', 'Hippocampal dentate gyrus': '28.9', 'Lamp5-lhx6 and chandelier': '26.8', 'Lower rhombic lip': '31.2', 'Mammillary body': '29.4', 'Medium spiny neuron': '24.0', 'Mge interneuron': '26.8', 'Midbrain-derived inhibitory': '26.4', 'Miscellaneous': '28.9', 'Splatter': '26.7', 'Thalamic excitatory': '30.1', 'Upper rhombic lip': '21.2', 'Upper-layer intratelencephalic': '27.7', 'Astrocyte': '28.6', 'Bergmann glia': '25.7', 'Central nervous system macrophage': '27.6', 'Choroid plexus epithelial cell': '25.5', 'Committed oligodendrocyte precursor': '27.9', 'Ependymal cell': '23.9', 'Oligodendrocyte': '30.7', 'Oligodendrocyte precursor cell': '24.8', 'Endothelial cell': '36.6', 'Pericyte': '37.8', 'Vascular associated smooth muscle cell': '32.6', 'Fibroblast': '28.1', 'Leukocyte': '37.8', 'Basophil': '186.0', 'Eosinophil': '134.0', 'Neutrophil': '257.6', 'Classical monocyte': '81.9', 'Non-classical monocyte': '94.6', 'Intermediate monocyte': '255.7', 'T-reg': '197.5', 'GdT-cell': '146.2', 'MAIT T-cell': '203.5', 'Memory CD4 T-cell': '133.6', 'Naive CD4 T-cell': '75.4', 'Memory CD8 T-cell': '141.2', 'Naive CD8 T-cell': '75.7', 'Memory B-cell': '125.5', 'Naive B-cell': '63.8', 'Plasmacytoid DC': '270.2', 'Myeloid DC': '275.9', 'NK-cell': '107.5', 'Total PBMC': '238.0', 'Vd2 gdTCR': '185.6', 'Memory CD4 T-cell TFH': '85.6', 'Memory CD4 T-cell Th2': '86.8', 'Memory CD4 T-cell Th17': '81.5', 'Memory CD4 T-cell Th1\\/Th17': '80.6', 'Non-Vd2 gdTCR': '220.1', 'Memory CD4 T-cell Th1': '85.7', 'Terminal effector memory CD4 T-cell': '193.2', 'Central memory CD8 T-cell': '176.8', 'Effector memory CD8 T-cell': '249.0', 'Terminal effector memory CD8 T-cell': '211.6', 'Switched memory B-cell': '198.8', 'Plasmablast': '377.9', 'Non-switched memory B-cell': '173.6', 'Exhausted memory B-cell': '183.0', 'Progenitor cell': '159.1', 'Naive CD4 T-cell activated': '221.1', 'Naive CD8 T-cell activated': '206.2', 'Memory T-reg': '92.4', 'Naive T-reg': '72.3'}
5GJQ, 5GJR, 5L4K, 5LN3, 5M32, 5T0C, 5T0G, 5T0H, 5T0I, 5T0J, 5VFP, 5VFQ, 5VFR, 5VFS, 5VFT, 5VFU, 5VGZ, 5VHF, 5VHH, 5VHI, 5VHS, 6MSB, 6MSD, 6MSE, 6MSG, 6MSH, 6MSJ, 6MSK, 6WJD, 6WJN, 7QXN, 7QXP, 7QXU, 7QXW, 7QXX, 7QY7, 7QYA, 7QYB, 7W37, 7W38, 7W39, 7W3A, 7W3B, 7W3C, 7W3F, 7W3G, 7W3H, 7W3I, 7W3J, 7W3K, 7W3M, 8CVT
{'Adipose Tissue': 104.41722591362128, 'Adrenal Gland': 77.89837209302326, 'Bladder': 106.9047619047619, 'Blood': 103.37514639397202, 'Blood Vessel': 113.74167041198504, 'Brain': 57.42566313398941, 'Breast': 110.6016339869281, 'Cervix Uteri': 119.17, 'Colon': 92.97251604621307, 'Esophagus': 97.599723183391, 'Fallopian Tube': 113.75777777777778, 'Heart': 51.94334727061557, 'Kidney': 59.01808988764044, 'Liver': 51.25298672566371, 'Lung': 123.78136678200693, 'Muscle': 116.19697384806972, 'Nerve': 126.56956381260096, 'Ovary': 91.97127777777776, 'Pancreas': 39.51692073170731, 'Pituitary': 96.80257950530036, 'Prostate': 115.59755102040818, 'Salivary Gland': 78.25660493827161, 'Skin': 128.09996683250415, 'Small Intestine': 95.007807486631, 'Spleen': 128.18095435684648, 'Stomach': 73.31426183844012, 'Testis': 115.22761772853184, 'Thyroid': 103.19022970903522, 'Uterus': 128.9875352112676, 'Vagina': 102.02814102564102}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
71.971064
0.364149
2,058
O60260
Q9UNN5
23307929
UbiNet, UbiBrowser
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
FAF1
MASNMDREMILADFQACTGIENIDEAITLLEQNNWDLVAAINGVIPQENGILQSEYGGETIPGPAFNPASHPASAPTSSSSSAFRPVMPSRQIVERQPRMLDFRVEYRDRNVDVVLEDTCTVGEIKQILENELQIPVSKMLLKGWKTGDVEDSTVLKSLHLPKNNSLYVLTPDLPPPSSSSHAGALQESLNQNFMLIITHREVQREYNLNFSGSSTIQEVKRNVYDLTSIPVRHQLWEGWPTSATDDSMCLAESGLSYPCHRLTVGRRSSPAQTREQSEEQITDVHMVSDSDGDDFEDATEFGVDDGEVFGMASSALRKSPMMPENAENEGDALLQFTAEFSSRYGDCHPVFFIGSLEAAFQEAFYVKARDRKLLAIYLHHDESVLTNVFCSQMLCAESIVSYLSQNFITWAWDLTKDSNRARFLTMCNRHFGSVVAQTIRTQKTDQFPLFLIIMGKRSSNEVLNVIQGNTTVDELMMRLMAAMEIFTAQQQEDIKDEDEREARENVKREQDEAYRLSLEADRAKREAHEREMAEQFRLEQIRKEQEEEREAIRLSLEQALPPEPKEENAEPVSKLRIRTPSGEFLERRFLASNKLQIVFDFVASKGFPWDEYKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLEAKE
Homo sapiens
Nucleus
Low tissue specificity
{'Ciliated cells': '20.5', 'Basal respiratory cells': '27.5', 'Club cells': '30.1', 'Ionocytes': '20.6', 'Mucus glandular cells': '20.7', 'Serous glandular cells': '24.9', 'Gastric mucus-secreting cells': '25.4', 'Proximal enterocytes': '17.2', 'Paneth cells': '13.0', 'Distal enterocytes': '15.2', 'Intestinal goblet cells': '17.3', 'Exocrine glandular cells': '-0.607', 'Basal prostatic cells': '19.6', 'Prostatic glandular cells': '19.2', 'Breast glandular cells': '0.498', 'Breast myoepithelial cells': '0.549', 'Glandular and luminal cells': '17.3', 'Secretory cells': '19.4', 'Basal keratinocytes': '29.6', 'Suprabasal keratinocytes': '36.0', 'Basal squamous epithelial cells': '37.7', 'Squamous epithelial cells': '35.4', 'Alveolar cells type 1': '0.062', 'Alveolar cells type 2': '0.256', 'Salivary duct cells': '23.0', 'Ductal cells': '0.400', 'Hepatocytes': '0.515', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.231', 'Distal tubular cells': '21.5', 'Collecting duct cells': '17.5', 'Mesothelial cells': '0.259', 'Sertoli cells': '-0.478', 'Granulosa cells': '14.1', 'Enteroendocrine cells': '11.5', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '-0.518', 'Excitatory neurons': '286.6', 'Inhibitory neurons': '267.2', 'Cone photoreceptor cells': '27.2', 'Rod photoreceptor cells': '31.9', 'Bipolar cells': '19.5', 'Horizontal cells': '15.7', 'Astrocytes': '192.0', 'Oligodendrocyte precursor cells': '253.3', 'Oligodendrocytes': '395.0', 'Microglial cells': '169.1', 'Muller glia cells': '19.1', 'Schwann cells': '0.122', 'Spermatogonia': '-0.200', 'Spermatocytes': '0.226', 'Early spermatids': '0.902', 'Late spermatids': '0.650', 'Oocytes': '33.8', 'Cytotrophoblasts': '14.2', 'Syncytiotrophoblasts': '14.9', 'Extravillous trophoblasts': '27.7', 'Endothelial cells': '15.1', 'Lymphatic endothelial cells': '26.8', 'Cardiomyocytes': '0.729', 'Skeletal myocytes': '-0.261', 'Smooth muscle cells': '19.7', 'Adipocytes': '16.0', 'Melanocytes': '0.370', 'Fibroblasts': '15.6', 'Peritubular cells': '-0.374', 'Endometrial stromal cells': '14.8', 'Ovarian stromal cells': '12.0', 'Undifferentiated cells': '27.8', 'T-cells': '28.4', 'B-cells': '28.4', 'Plasma cells': '37.0', 'Nk-cells': '19.6', 'Granulocytes': '29.5', 'Monocytes': '20.8', 'Macrophages': '17.7', 'Hofbauer cells': '12.3', 'Kupffer cells': '7.9', 'Dendritic cells': '3.2', 'Langerhans cells': '0.243', 'Erythroid cells': '-0.078', 'Adipocytes (Subcutaneous)': '-0.078', 'Adipocytes (Visceral)': '0.037', 'Breast glandular cells (progenitors)': '0.482', 'Adipocytes (Breast)': '-0.449', 'Colon enterocytes': '-0.249', 'Colon enteroendocrine cells': '0.126', 'Enteric glia cells': '-0.264', 'Mitotic cells (Colon)': '-0.227', 'Mitotic cells (Heart)': '0.475', 'Podocytes': '0.006', 'Ascending Loop of Henle cells': '0.467', 'Intercalated cells': '0.083', 'Cholangiocyte': '0.363', 'NK-cells (Liver)': '-0.383', 'Respiratory ciliated cells': '0.027', 'Mitotic cells (Lung)': '0.131', 'NK-cells (Lung)': '-0.273', 'B-cells (Lung)': '-0.310', 'Alpha cells': '0.267', 'Beta cells': '0.129', 'Prostate glandular cells': '-0.098', 'Prostate basal glandular cells': '0.129', 'Urothelial cells': '-0.021', 'Keratinocyte (other)': '0.589', 'Keratinocyte (granular)': '0.014', 'Hair cortex cells': '-0.105', 'Inner root sheath cells': '0.006', 'Outer root sheath cells': '-0.045', 'Sebaceous gland cells': '-0.221', 'Eccrine sweat gland cells': '-0.176', 'Adipocytes (Skin)': '-0.358', 'Mitotic cells (Skin)': '0.364', 'Parietal cells': '-0.614', 'Chief cells': '-0.451', 'Gastric mucous cells': '-0.456', 'Gastric enteroendocrine cells': '-0.424', 'Mitotic cells (Stomach)': '-0.016', 'Parafollicular cells': '0.129', 'Thyroid glandular cells': '0.617', 'Mitotic cells (Thyroid)': '-0.103', 'Adrenal cortex cells': '0.382', 'Adrenal medulla cells': '0.045', 'Mitotic cells (Adrenal gland)': '0.238', 'Minor salivary glandular cells': '0.317', 'Minor salivary gland ductal cells': '-0.038', 'Minor salivary gland basal cells': '0.475', 'Mitotic cells (Minor salivary gland)': '0.526', 'Adipocytes (Minor salivary gland)': '0.257', 'Somatotropes': '0.363', 'Lactotropes': '0.333', 'Gonadotropes': '0.060', 'Corticotropes': '0.127', 'Thyrotropes': '0.231', 'Undifferentiated cells (Pituitary gland)': '-0.206', 'Mitotic cells (Spleen)': '-0.048', 'Platelets': '-0.202', 'Erythrocytes': '-0.111', 'Hematopoietic stem cells': '-0.194', 'B-cells (Spleen)': '0.307', 'NK-cells (Spleen)': '0.178', 'Amygdala excitatory': '421.2', 'Cerebellar inhibitory': '388.6', 'Cge interneuron': '355.6', 'Deep-layer corticothalamic and 6b': '443.5', 'Deep-layer intratelencephalic': '433.4', 'Deep-layer near-projecting': '461.4', 'Eccentric medium spiny neuron': '439.7', 'Hippocampal ca1-3': '432.0', 'Hippocampal ca4': '391.3', 'Hippocampal dentate gyrus': '514.8', 'Lamp5-lhx6 and chandelier': '359.1', 'Lower rhombic lip': '401.2', 'Mammillary body': '516.2', 'Medium spiny neuron': '426.2', 'Mge interneuron': '444.6', 'Midbrain-derived inhibitory': '396.2', 'Miscellaneous': '431.0', 'Splatter': '383.3', 'Thalamic excitatory': '360.3', 'Upper rhombic lip': '450.3', 'Upper-layer intratelencephalic': '417.6', 'Astrocyte': '363.8', 'Bergmann glia': '330.6', 'Central nervous system macrophage': '476.2', 'Choroid plexus epithelial cell': '364.6', 'Committed oligodendrocyte precursor': '457.7', 'Ependymal cell': '226.6', 'Oligodendrocyte': '706.7', 'Oligodendrocyte precursor cell': '505.3', 'Endothelial cell': '395.1', 'Pericyte': '361.1', 'Vascular associated smooth muscle cell': '349.0', 'Fibroblast': '347.1', 'Leukocyte': '493.9', 'Basophil': '1.2', 'Eosinophil': '0.7', 'Neutrophil': '1.2', 'Classical monocyte': '15.7', 'Non-classical monocyte': '22.9', 'Intermediate monocyte': '2.2', 'T-reg': '1.9', 'GdT-cell': '1.1', 'MAIT T-cell': '1.9', 'Memory CD4 T-cell': '1.1', 'Naive CD4 T-cell': '28.2', 'Memory CD8 T-cell': '1.0', 'Naive CD8 T-cell': '25.9', 'Memory B-cell': '0.8', 'Naive B-cell': '20.3', 'Plasmacytoid DC': '1.2', 'Myeloid DC': '1.7', 'NK-cell': '28.2', 'Total PBMC': '1.8', 'Vd2 gdTCR': '2.0', 'Memory CD4 T-cell TFH': '25.5', 'Memory CD4 T-cell Th2': '27.9', 'Memory CD4 T-cell Th17': '27.9', 'Memory CD4 T-cell Th1\\/Th17': '30.6', 'Non-Vd2 gdTCR': '1.3', 'Memory CD4 T-cell Th1': '28.3', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '2.6', 'Terminal effector memory CD8 T-cell': '2.3', 'Switched memory B-cell': '2.1', 'Plasmablast': '1.6', 'Non-switched memory B-cell': '1.8', 'Exhausted memory B-cell': '2.0', 'Progenitor cell': '2.0', 'Naive CD4 T-cell activated': '16.3', 'Naive CD8 T-cell activated': '19.7', 'Memory T-reg': '27.3', 'Naive T-reg': '26.2'}
1H8C, 2DZM, 2EC4, 3E21, 3QC8, 3QCA, 3QQ8, 3QWZ, 3QX1, 3R3M, 7FGM, 7FGN, 8KG2
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
78.153723
0.466138
1,132
O60260
Q9WVS6
33082525
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
Prkn
MIVFVRFNSSYGFPVEVDSDTSILQLKEVVAKRQGVPADQLRVIFAGKELPNHLTVQNCDLEQQSIVHIVQRPRRRSHETNASGGDEPQSTSEGSIWESRSLTRVDLSSHTLPVDSVGLAVILDTDSKRDSEAARGPVKPTYNSFFIYCKGPCHKVQPGKLRVQCGTCKQATLTLAQGPSCWDDVLIPNRMSGECQSPDCPGTRAEFFFKCGAHPTSDKDTSVALNLITSNRRSIPCIACTDVRSPVLVFQCNHRHVICLDCFHLYCVTRLNDRQFVHDAQLGYSLPCVAGCPNSLIKELHHFRILGEEQYTRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEQGQRKVTCEGGNGLGCGFVFCRDCKEAYHEGDCDSLLEPSGATSQAYRVDKRAAEQARWEEASKETIKKTTKPCPRCNVPIEKNGGCMHMKCPQPQCKLEWCWNCGCEWNRACMGDHWFDV
Mus musculus
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Not found
{}
1MG8, 2ZEQ, 3B1L
{}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
77.196875
0.423621
1,708
O60260
Q9Y277
33082525, 23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
VDAC3
MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA
Homo sapiens
Mitochondrion outer membrane, Membrane
Group enriched (heart muscle, skeletal muscle, tongue)
{'Ciliated cells': '131.4', 'Basal respiratory cells': '188.5', 'Club cells': '77.2', 'Ionocytes': '121.1', 'Mucus glandular cells': '34.6', 'Serous glandular cells': '85.5', 'Gastric mucus-secreting cells': '34.2', 'Proximal enterocytes': '119.2', 'Paneth cells': '107.0', 'Distal enterocytes': '100.6', 'Intestinal goblet cells': '86.3', 'Exocrine glandular cells': '-0.518', 'Basal prostatic cells': '59.0', 'Prostatic glandular cells': '42.5', 'Breast glandular cells': '-0.048', 'Breast myoepithelial cells': '-0.041', 'Glandular and luminal cells': '52.5', 'Secretory cells': '86.5', 'Basal keratinocytes': '86.2', 'Suprabasal keratinocytes': '112.5', 'Basal squamous epithelial cells': '60.3', 'Squamous epithelial cells': '84.6', 'Alveolar cells type 1': '-0.089', 'Alveolar cells type 2': '-0.034', 'Salivary duct cells': '50.9', 'Ductal cells': '0.527', 'Hepatocytes': '0.475', 'Cholangiocytes': '61.1', 'Proximal tubular cells': '0.295', 'Distal tubular cells': '230.5', 'Collecting duct cells': '62.2', 'Mesothelial cells': '0.246', 'Sertoli cells': '-0.286', 'Granulosa cells': '96.6', 'Enteroendocrine cells': '89.5', 'Pancreatic endocrine cells': '113.8', 'Leydig cells': '-0.324', 'Excitatory neurons': '61.1', 'Inhibitory neurons': '75.7', 'Cone photoreceptor cells': '51.0', 'Rod photoreceptor cells': '73.0', 'Bipolar cells': '79.6', 'Horizontal cells': '98.2', 'Astrocytes': '48.0', 'Oligodendrocyte precursor cells': '35.8', 'Oligodendrocytes': '32.2', 'Microglial cells': '25.0', 'Muller glia cells': '71.9', 'Schwann cells': '0.082', 'Spermatogonia': '-0.032', 'Spermatocytes': '0.410', 'Early spermatids': '0.859', 'Late spermatids': '0.353', 'Oocytes': '242.6', 'Cytotrophoblasts': '155.8', 'Syncytiotrophoblasts': '59.2', 'Extravillous trophoblasts': '109.2', 'Endothelial cells': '67.2', 'Lymphatic endothelial cells': '96.6', 'Cardiomyocytes': '0.840', 'Skeletal myocytes': '0.719', 'Smooth muscle cells': '79.3', 'Adipocytes': '70.1', 'Melanocytes': '0.159', 'Fibroblasts': '77.9', 'Peritubular cells': '-0.206', 'Endometrial stromal cells': '57.9', 'Ovarian stromal cells': '82.0', 'Undifferentiated cells': '134.6', 'T-cells': '70.4', 'B-cells': '47.8', 'Plasma cells': '94.5', 'Nk-cells': '76.2', 'Granulocytes': '62.5', 'Monocytes': '46.4', 'Macrophages': '65.2', 'Hofbauer cells': '133.4', 'Kupffer cells': '50.8', 'Dendritic cells': '104.9', 'Langerhans cells': '0.340', 'Erythroid cells': '0.067', 'Adipocytes (Subcutaneous)': '-0.076', 'Adipocytes (Visceral)': '0.116', 'Breast glandular cells (progenitors)': '-0.041', 'Adipocytes (Breast)': '0.238', 'Colon enterocytes': '-0.165', 'Colon enteroendocrine cells': '0.197', 'Enteric glia cells': '-0.109', 'Mitotic cells (Colon)': '-0.165', 'Mitotic cells (Heart)': '0.382', 'Podocytes': '-0.049', 'Ascending Loop of Henle cells': '0.465', 'Intercalated cells': '0.016', 'Cholangiocyte': '0.377', 'NK-cells (Liver)': '-0.354', 'Respiratory ciliated cells': '0.135', 'Mitotic cells (Lung)': '0.352', 'NK-cells (Lung)': '0.025', 'B-cells (Lung)': '-0.093', 'Alpha cells': '0.383', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.419', 'Prostate basal glandular cells': '-0.089', 'Urothelial cells': '-0.065', 'Keratinocyte (other)': '0.109', 'Keratinocyte (granular)': '-0.176', 'Hair cortex cells': '0.036', 'Inner root sheath cells': '0.091', 'Outer root sheath cells': '0.224', 'Sebaceous gland cells': '0.311', 'Eccrine sweat gland cells': '0.082', 'Adipocytes (Skin)': '0.061', 'Mitotic cells (Skin)': '0.442', 'Parietal cells': '-0.573', 'Chief cells': '-0.602', 'Gastric mucous cells': '-0.319', 'Gastric enteroendocrine cells': '-0.486', 'Mitotic cells (Stomach)': '0.158', 'Parafollicular cells': '0.095', 'Thyroid glandular cells': '0.520', 'Mitotic cells (Thyroid)': '-0.056', 'Adrenal cortex cells': '0.548', 'Adrenal medulla cells': '0.088', 'Mitotic cells (Adrenal gland)': '0.498', 'Minor salivary glandular cells': '0.036', 'Minor salivary gland ductal cells': '-0.201', 'Minor salivary gland basal cells': '0.581', 'Mitotic cells (Minor salivary gland)': '0.658', 'Adipocytes (Minor salivary gland)': '0.253', 'Somatotropes': '-0.050', 'Lactotropes': '0.118', 'Gonadotropes': '0.196', 'Corticotropes': '0.119', 'Thyrotropes': '0.428', 'Undifferentiated cells (Pituitary gland)': '0.082', 'Mitotic cells (Spleen)': '0.067', 'Platelets': '0.032', 'Erythrocytes': '0.034', 'Hematopoietic stem cells': '-0.041', 'B-cells (Spleen)': '0.193', 'NK-cells (Spleen)': '0.092', 'Amygdala excitatory': '59.5', 'Cerebellar inhibitory': '111.3', 'Cge interneuron': '95.8', 'Deep-layer corticothalamic and 6b': '78.1', 'Deep-layer intratelencephalic': '74.7', 'Deep-layer near-projecting': '94.6', 'Eccentric medium spiny neuron': '58.5', 'Hippocampal ca1-3': '89.8', 'Hippocampal ca4': '94.7', 'Hippocampal dentate gyrus': '70.2', 'Lamp5-lhx6 and chandelier': '115.0', 'Lower rhombic lip': '106.3', 'Mammillary body': '80.8', 'Medium spiny neuron': '54.3', 'Mge interneuron': '109.6', 'Midbrain-derived inhibitory': '120.1', 'Miscellaneous': '83.1', 'Splatter': '93.3', 'Thalamic excitatory': '103.7', 'Upper rhombic lip': '102.8', 'Upper-layer intratelencephalic': '73.7', 'Astrocyte': '74.5', 'Bergmann glia': '77.7', 'Central nervous system macrophage': '40.3', 'Choroid plexus epithelial cell': '60.9', 'Committed oligodendrocyte precursor': '52.6', 'Ependymal cell': '73.7', 'Oligodendrocyte': '49.8', 'Oligodendrocyte precursor cell': '58.7', 'Endothelial cell': '51.4', 'Pericyte': '65.8', 'Vascular associated smooth muscle cell': '57.7', 'Fibroblast': '65.2', 'Leukocyte': '53.4', 'Basophil': '167.4', 'Eosinophil': '183.9', 'Neutrophil': '169.4', 'Classical monocyte': '64.9', 'Non-classical monocyte': '85.0', 'Intermediate monocyte': '264.9', 'T-reg': '233.5', 'GdT-cell': '146.1', 'MAIT T-cell': '196.2', 'Memory CD4 T-cell': '156.0', 'Naive CD4 T-cell': '118.0', 'Memory CD8 T-cell': '146.5', 'Naive CD8 T-cell': '95.7', 'Memory B-cell': '127.0', 'Naive B-cell': '40.8', 'Plasmacytoid DC': '392.7', 'Myeloid DC': '348.9', 'NK-cell': '117.3', 'Total PBMC': '286.0', 'Vd2 gdTCR': '238.6', 'Memory CD4 T-cell Th1\\/Th17': '104.9', 'Memory CD4 T-cell Th17': '106.6', 'Memory CD4 T-cell Th2': '107.4', 'Non-Vd2 gdTCR': '261.1', 'Memory CD4 T-cell Th1': '96.9', 'Memory CD4 T-cell TFH': '103.0', 'Terminal effector memory CD4 T-cell': '226.3', 'Central memory CD8 T-cell': '183.0', 'Effector memory CD8 T-cell': '265.5', 'Terminal effector memory CD8 T-cell': '264.5', 'Non-switched memory B-cell': '162.0', 'Plasmablast': '337.9', 'Switched memory B-cell': '199.4', 'Exhausted memory B-cell': '183.9', 'Progenitor cell': '246.5', 'Memory T-reg': '103.8', 'Naive CD4 T-cell activated': '101.0', 'Naive CD8 T-cell activated': '112.3', 'Naive T-reg': '104.0'}
null
{'Adipose Tissue': 83.04117940199336, 'Adrenal Gland': 87.50503875968992, 'Bladder': 108.99571428571429, 'Blood': 70.49785145317546, 'Blood Vessel': 117.42596254681648, 'Brain': 115.8098349735049, 'Breast': 79.35596949891067, 'Cervix Uteri': 95.35157894736842, 'Colon': 131.5236842105263, 'Esophagus': 125.20060207612455, 'Fallopian Tube': 109.63444444444444, 'Heart': 142.3059175377468, 'Kidney': 64.55988764044943, 'Liver': 45.83389380530973, 'Lung': 88.51212802768167, 'Muscle': 276.6498630136986, 'Nerve': 113.09830371567044, 'Ovary': 88.72733333333333, 'Pancreas': 35.484756097560975, 'Pituitary': 91.14932862190813, 'Prostate': 84.13951020408163, 'Salivary Gland': 75.0212962962963, 'Skin': 85.89800995024876, 'Small Intestine': 95.65700534759358, 'Spleen': 94.7308713692946, 'Stomach': 79.82389972144847, 'Testis': 169.51944598337948, 'Thyroid': 121.08199081163858, 'Uterus': 115.88985915492958, 'Vagina': 95.9322435897436}
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[44.95, 59.54, 80.53, 89.75, 94.08, 95.26, 96.8, 94.11, 95.67, 96.2, 96.05, 96.99, 96.43, 97.72, 97.4, 97.61, 97.97, 97.67, 97.13, 96.65, 95.77, 97.25, 96.06, 96.66, 96.74, 96.58, 97.87, 97.48, 97.83, 97.65, 97.87, 97.85, 97.11, 95.99, 94.22, 91.18, 90.47, 91.68, 96.35, 97.59, 97.99, 97.94, 98.04, 97.62, 97.59, 95.78, 97.02, 95.58, 91.63, 91.51, 93.5, 91.13, 94.69, 95.93, 96.0, 97.59, 97.66, 98.25, 98.4, 98.23, 98.1, 96.94, 95.22, 94.21, 88.63, 90.68, 92.97, 93.6, 96.87, 97.58, 97.95, 98.28, 98.35, 98.15, 97.75, 96.52, 96.13, 92.89, 94.76, 95.78, 97.8, 97.15, 98.11, 98.06, 98.04, 97.4, 97.18, 95.88, 92.99, 90.05, 91.54, 94.11, 93.56, 93.6, 96.89, 97.43, 97.96, 97.73, 97.51, 96.33, 95.66, 94.49, 94.44, 95.02, 93.9, 91.08, 92.22, 89.51, 89.95, 91.3, 91.49, 93.41, 95.71, 97.0, 97.41, 97.77, 97.37, 96.85, 95.57, 94.2, 92.52, 93.76, 96.0, 97.23, 97.99, 97.76, 97.62, 95.54, 95.85, 91.1, 84.03, 77.6, 73.1, 80.43, 85.1, 92.34, 93.88, 95.92, 96.97, 97.93, 98.32, 98.4, 98.36, 97.68, 96.66, 94.87, 93.76, 93.88, 96.78, 97.53, 98.2, 98.33, 98.53, 98.17, 97.83, 96.75, 95.99, 93.96, 93.15, 92.37, 93.75, 93.78, 95.37, 94.06, 93.99, 95.61, 96.5, 98.2, 98.39, 98.43, 98.2, 97.62, 96.89, 95.57, 94.36, 92.62, 94.61, 96.77, 97.47, 98.07, 98.21, 98.46, 98.05, 98.0, 97.07, 96.07, 93.94, 95.4, 96.74, 97.5, 97.46, 97.94, 98.33, 98.44, 98.59, 98.36, 97.7, 97.45, 96.06, 95.17, 97.2, 97.95, 98.08, 98.58, 98.44, 98.41, 97.66, 97.42, 97.26, 96.13, 96.4, 94.35, 93.96, 92.79, 89.14, 90.42, 94.16, 95.61, 96.76, 98.25, 98.55, 98.7, 98.62, 98.54, 98.4, 97.86, 96.46, 96.14, 94.36, 96.43, 97.85, 98.05, 98.47, 98.51, 98.67, 98.49, 98.37, 97.16, 95.11, 94.49, 95.65, 97.09, 98.15, 98.49, 98.64, 98.61, 98.65, 98.48, 98.35, 98.04, 97.19, 95.46, 95.15, 94.77, 97.67, 97.93, 98.41, 98.51, 98.55, 98.42, 98.11, 98.13, 97.7, 96.44, 95.1, 94.37, 93.9, 91.94, 92.34, 88.99, 88.09, 88.54, 95.77, 96.92, 96.85, 97.81, 98.24, 98.07, 97.95, 97.98, 97.73, 94.92, 89.93]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
95.439717
0.389859
2,404
O60260
Q9Y2W6
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
TDRKH
MSTERTSWTSLSTIQKIALGLGIPASATVAYILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGDERVLLISGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEELRKRIAHSAETRVPRKQPISVRREDMTEPGGAGEPALWKNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSNGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETKKSSGEITHTLSCLSLSEAASMSGDDNLEDDYLL
Homo sapiens
Cytoplasm, Mitochondrion
Tissue enhanced (parathyroid gland, testis)
{'Ciliated cells': '1.2', 'Basal respiratory cells': '1.6', 'Club cells': '2.6', 'Ionocytes': '1.1', 'Mucus glandular cells': '2.9', 'Serous glandular cells': '2.8', 'Gastric mucus-secreting cells': '2.9', 'Proximal enterocytes': '0.2', 'Paneth cells': '0.2', 'Distal enterocytes': '0.9', 'Intestinal goblet cells': '0.8', 'Exocrine glandular cells': '-0.701', 'Basal prostatic cells': '7.3', 'Prostatic glandular cells': '5.5', 'Breast glandular cells': '0.479', 'Breast myoepithelial cells': '0.424', 'Glandular and luminal cells': '1.1', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.5', 'Suprabasal keratinocytes': '1.2', 'Basal squamous epithelial cells': '0.4', 'Squamous epithelial cells': '0.6', 'Alveolar cells type 1': '0.036', 'Alveolar cells type 2': '0.503', 'Salivary duct cells': '1.5', 'Ductal cells': '0.651', 'Hepatocytes': '0.443', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.194', 'Distal tubular cells': '6.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.107', 'Sertoli cells': '-0.316', 'Granulosa cells': '1.4', 'Enteroendocrine cells': '0.7', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '-0.343', 'Excitatory neurons': '6.4', 'Inhibitory neurons': '5.6', 'Cone photoreceptor cells': '6.8', 'Rod photoreceptor cells': '2.2', 'Bipolar cells': '3.8', 'Horizontal cells': '4.4', 'Astrocytes': '2.2', 'Oligodendrocyte precursor cells': '5.7', 'Oligodendrocytes': '7.7', 'Microglial cells': '2.7', 'Muller glia cells': '1.5', 'Schwann cells': '0.166', 'Spermatogonia': '0.004', 'Spermatocytes': '0.535', 'Early spermatids': '0.664', 'Late spermatids': '0.407', 'Oocytes': '58.8', 'Cytotrophoblasts': '2.6', 'Syncytiotrophoblasts': '2.2', 'Extravillous trophoblasts': '3.0', 'Endothelial cells': '1.7', 'Lymphatic endothelial cells': '3.5', 'Cardiomyocytes': '0.654', 'Skeletal myocytes': '0.123', 'Smooth muscle cells': '1.1', 'Adipocytes': '1.0', 'Melanocytes': '0.136', 'Fibroblasts': '0.6', 'Peritubular cells': '-0.316', 'Endometrial stromal cells': '0.3', 'Ovarian stromal cells': '0.5', 'Undifferentiated cells': '1.5', 'T-cells': '3.1', 'B-cells': '2.6', 'Plasma cells': '1.7', 'Nk-cells': '1.2', 'Granulocytes': '2.7', 'Monocytes': '1.3', 'Macrophages': '2.5', 'Hofbauer cells': '4.9', 'Kupffer cells': '1.5', 'Dendritic cells': '2.2', 'Langerhans cells': '0.097', 'Erythroid cells': '-0.022', 'Adipocytes (Subcutaneous)': '0.307', 'Adipocytes (Visceral)': '0.238', 'Breast glandular cells (progenitors)': '0.305', 'Adipocytes (Breast)': '-0.400', 'Colon enterocytes': '-0.167', 'Colon enteroendocrine cells': '0.235', 'Enteric glia cells': '0.061', 'Mitotic cells (Colon)': '-0.140', 'Mitotic cells (Heart)': '0.493', 'Podocytes': '-0.025', 'Ascending Loop of Henle cells': '0.356', 'Intercalated cells': '-0.004', 'Cholangiocyte': '0.219', 'NK-cells (Liver)': '-0.190', 'Respiratory ciliated cells': '-0.052', 'Mitotic cells (Lung)': '0.254', 'NK-cells (Lung)': '-0.256', 'B-cells (Lung)': '-0.262', 'Alpha cells': '0.410', 'Beta cells': '0.257', 'Prostate glandular cells': '0.661', 'Prostate basal glandular cells': '0.452', 'Urothelial cells': '0.150', 'Keratinocyte (other)': '0.055', 'Keratinocyte (granular)': '-0.219', 'Hair cortex cells': '0.276', 'Inner root sheath cells': '0.321', 'Outer root sheath cells': '0.334', 'Sebaceous gland cells': '0.029', 'Eccrine sweat gland cells': '0.341', 'Adipocytes (Skin)': '0.133', 'Mitotic cells (Skin)': '0.407', 'Parietal cells': '-0.529', 'Chief cells': '-0.424', 'Gastric mucous cells': '-0.309', 'Gastric enteroendocrine cells': '-0.316', 'Mitotic cells (Stomach)': '0.135', 'Parafollicular cells': '0.116', 'Thyroid glandular cells': '0.361', 'Mitotic cells (Thyroid)': '-0.021', 'Adrenal cortex cells': '0.451', 'Adrenal medulla cells': '0.226', 'Mitotic cells (Adrenal gland)': '0.402', 'Minor salivary glandular cells': '0.597', 'Minor salivary gland ductal cells': '0.336', 'Minor salivary gland basal cells': '-0.211', 'Mitotic cells (Minor salivary gland)': '-0.104', 'Adipocytes (Minor salivary gland)': '-0.097', 'Somatotropes': '0.195', 'Lactotropes': '0.229', 'Gonadotropes': '0.047', 'Corticotropes': '0.169', 'Thyrotropes': '0.235', 'Undifferentiated cells (Pituitary gland)': '-0.052', 'Mitotic cells (Spleen)': '0.027', 'Platelets': '0.077', 'Erythrocytes': '-0.139', 'Hematopoietic stem cells': '-0.037', 'B-cells (Spleen)': '0.089', 'NK-cells (Spleen)': '0.142', 'Amygdala excitatory': '15.1', 'Cerebellar inhibitory': '11.3', 'Cge interneuron': '9.8', 'Deep-layer corticothalamic and 6b': '15.0', 'Deep-layer intratelencephalic': '14.2', 'Deep-layer near-projecting': '11.5', 'Eccentric medium spiny neuron': '13.3', 'Hippocampal ca1-3': '15.9', 'Hippocampal ca4': '14.3', 'Hippocampal dentate gyrus': '17.9', 'Lamp5-lhx6 and chandelier': '8.2', 'Lower rhombic lip': '15.0', 'Mammillary body': '8.8', 'Medium spiny neuron': '12.8', 'Mge interneuron': '10.2', 'Midbrain-derived inhibitory': '16.4', 'Miscellaneous': '14.5', 'Splatter': '13.7', 'Thalamic excitatory': '9.5', 'Upper rhombic lip': '21.6', 'Upper-layer intratelencephalic': '12.4', 'Astrocyte': '5.2', 'Bergmann glia': '7.3', 'Central nervous system macrophage': '12.2', 'Choroid plexus epithelial cell': '6.9', 'Committed oligodendrocyte precursor': '12.3', 'Ependymal cell': '4.9', 'Oligodendrocyte': '12.3', 'Oligodendrocyte precursor cell': '16.1', 'Endothelial cell': '5.1', 'Pericyte': '1.4', 'Vascular associated smooth muscle cell': '4.6', 'Fibroblast': '4.3', 'Leukocyte': '9.4', 'Basophil': '9.5', 'Eosinophil': '2.0', 'Neutrophil': '0.6', 'Classical monocyte': '0.9', 'Non-classical monocyte': '7.4', 'Intermediate monocyte': '9.2', 'T-reg': '19.1', 'GdT-cell': '8.2', 'MAIT T-cell': '48.9', 'Memory CD4 T-cell': '7.6', 'Naive CD4 T-cell': '15.2', 'Memory CD8 T-cell': '8.3', 'Naive CD8 T-cell': '13.4', 'Memory B-cell': '4.0', 'Naive B-cell': '6.4', 'Plasmacytoid DC': '15.7', 'Myeloid DC': '5.6', 'NK-cell': '14.2', 'Total PBMC': '10.5', 'Vd2 gdTCR': '23.2', 'Memory CD4 T-cell Th1\\/Th17': '21.5', 'Memory CD4 T-cell Th17': '20.3', 'Memory CD4 T-cell Th2': '14.1', 'Non-Vd2 gdTCR': '18.8', 'Memory CD4 T-cell Th1': '16.1', 'Memory CD4 T-cell TFH': '13.7', 'Terminal effector memory CD4 T-cell': '25.1', 'Central memory CD8 T-cell': '21.3', 'Effector memory CD8 T-cell': '19.1', 'Terminal effector memory CD8 T-cell': '16.8', 'Non-switched memory B-cell': '8.8', 'Plasmablast': '3.9', 'Switched memory B-cell': '8.6', 'Exhausted memory B-cell': '6.0', 'Progenitor cell': '12.9', 'Memory T-reg': '15.4', 'Naive CD4 T-cell activated': '7.7', 'Naive CD8 T-cell activated': '8.3', 'Naive T-reg': '13.4'}
2DIQ, 3FDR, 5J39, 6B57, 6PI7
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[1.0, 1.0, 0.98, 0.99, 0.98, 0.86, 0.72, 0.75, 0.76, 0.82, 0.28, 0.48, 0.67, 0.76, 0.46, 0.48, 0.53, 0.56, 0.39, 0.54, 0.66, 0.4, 0.58, 0.53, 0.46, 0.53, 0.53, 0.5, 0.54, 0.51, 0.6, 0.59, 0.6, 0.6, 0.52, 0.7, 0.58, 0.54, 0.41, 0.38, 0.55, 0.45, 0.67, 0.81, 0.61, 0.7, 0.9, 0.37, 0.56, 0.82, 0.76, 0.69, 0.33, 0.65, 0.35, 0.72, 0.14, 0.68, 0.0, 0.58, 0.42, 0.74, 0.15, 0.08, 0.69, 0.43, 0.0, 0.32, 0.35, 0.91, 0.89, 0.13, 0.55, 0.31, 0.09, 0.62, 0.46, 0.05, 0.36, 0.81, 0.68, 0.09, 0.5, 0.05, 0.63, 0.01, 0.28, 0.28, 0.44, 0.83, 0.73, 0.45, 0.58, 0.7, 0.76, 0.43, 0.21, 0.15, 0.01, 0.31, 0.02, 0.2, 0.12, 0.5, 0.15, 0.48, 0.26, 0.01, 0.59, 0.55, 0.0, 0.5, 0.55, 0.25, 0.0, 0.6, 0.54, 0.18, 0.18, 0.46, 0.35, 0.36, 0.47, 0.84, 0.21, 0.82, 0.29, 0.64, 0.1, 0.69, 0.02, 0.27, 0.22, 0.57, 0.01, 0.05, 0.58, 0.38, 0.01, 0.3, 0.28, 0.89, 0.69, 0.13, 0.71, 0.25, 0.14, 0.68, 0.56, 0.06, 0.26, 0.87, 0.69, 0.08, 0.53, 0.05, 0.66, 0.11, 0.45, 0.21, 0.35, 0.91, 0.36, 0.76, 0.94, 0.65, 0.51, 0.19, 0.53, 0.57, 0.49, 0.19, 0.37, 0.0, 0.39, 0.02, 0.35, 0.28, 0.2, 0.34, 0.64, 0.32, 0.01, 0.46, 0.34, 0.0, 0.35, 0.67, 0.26, 0.0, 0.47, 0.5, 0.27, 0.09, 0.55, 0.4, 0.05, 0.42, 0.47, 0.23, 0.27, 0.61, 0.61, 0.1, 0.45, 0.63, 0.19, 0.09, 0.76, 0.65, 0.12, 0.56, 0.6, 0.07, 0.61, 0.54, 0.61, 0.22, 0.49, 0.78, 0.54, 0.66, 0.91, 0.88, 0.97, 0.75, 0.93, 0.94, 0.92, 0.94, 1.0, 0.9, 0.97, 0.96, 0.84, 0.83, 0.96, 0.86, 0.98, 0.98, 0.99, 1.0, 1.0, 1.0, 0.98, 1.0, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.88, 1.0, 0.9, 1.0, 0.99, 0.99, 0.99, 0.88, 0.99, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.92, 0.98, 0.9, 0.91, 0.91, 0.9, 0.86, 0.91, 0.87, 0.94, 0.89, 0.92, 0.67, 0.84, 0.56, 0.19, 0.7, 0.76, 0.09, 0.76, 0.16, 0.82, 0.21, 0.76, 0.65, 0.59, 0.37, 0.27, 0.11, 0.27, 0.0, 0.03, 0.01, 0.03, 0.07, 0.16, 0.49, 0.34, 0.0, 0.25, 0.15, 0.0, 0.05, 0.02, 0.02, 0.09, 0.17, 0.17, 0.55, 0.23, 0.06, 0.28, 0.47, 0.01, 0.17, 0.59, 0.08, 0.16, 0.63, 0.42, 0.01, 0.14, 0.75, 0.52, 0.03, 0.61, 0.95, 0.29, 0.84, 0.71, 0.44, 0.97, 0.21, 0.82, 0.25, 0.67, 0.68, 0.51, 0.33, 0.23, 0.04, 0.0, 0.0, 0.24, 0.12, 0.86, 0.79, 0.28, 0.48, 0.2, 0.06, 0.07, 0.01, 0.0, 0.37, 0.02, 0.39, 0.21, 0.71, 0.31, 0.99, 0.65, 0.55, 0.21, 0.08, 0.14, 0.01, 0.14, 0.01, 0.02, 0.04, 0.08, 0.0, 0.06, 0.27, 0.11, 0.5, 0.06, 0.3, 0.38, 0.69, 0.43, 0.0, 0.06, 0.46, 0.13, 0.43, 0.75, 0.55, 0.02, 0.31, 0.77, 0.11, 0.46, 0.05, 0.04, 0.1, 0.1, 0.27, 0.0, 0.14, 0.03, 0.05, 0.24, 0.07, 0.21, 0.22, 0.41, 0.6, 0.96, 0.73, 0.09, 0.51, 0.46, 0.61, 0.0, 0.11, 0.61, 0.13, 0.0, 0.32, 0.63, 0.09, 0.0, 0.31, 0.08, 0.01, 0.51, 0.07, 0.26, 0.52, 0.01, 0.15, 0.03, 0.19, 0.02, 0.4, 0.43, 0.4, 0.37, 0.76, 0.42, 0.71, 0.72, 0.48, 0.62, 0.25, 0.01, 0.27, 0.01, 0.21, 0.01, 0.08, 0.11, 0.28, 0.61, 0.88, 0.65, 0.78, 0.45, 0.36, 0.21, 0.0, 0.04, 0.43, 0.23, 0.0, 0.29, 0.8, 0.43, 0.5, 0.22, 0.07, 0.48, 0.51, 0.47, 0.83, 0.7, 0.72, 0.85, 0.72, 0.87, 0.75, 0.96, 0.76, 0.95, 0.72, 0.79, 0.86, 0.92, 0.87, 0.92, 0.96, 0.99, 0.97, 0.99, 0.95, 0.96, 0.93, 0.97, 0.94, 0.83, 0.94, 0.93, 1.0, 0.93, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.8, 0.9, 0.75, 0.83, 0.87, 0.89, 1.0, 0.86, 0.96, 0.83, 0.9, 0.93, 0.87, 0.84, 0.88, 0.94, 0.9, 0.93, 0.9, 0.97, 0.89, 0.99, 0.99, 1.0, 0.96, 1.0, 0.94, 1.0]
null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
74.09025
0.515829
1,380
O60260
Q9Y3D6
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
FIS1
MEAVLNELVSVEDLLKFEKKFQSEKAAGSVSKSTQFEYAWCLVRSKYNDDIRKGIVLLEELLPKGSKEEQRDYVFYLAVGNYRLKEYEKALKYVRGLLQTEPQNNQAKELERLIDKAMKKDGLVGMAIVGGMALGVAGLAGLIGLAVSKSKS
Homo sapiens
Mitochondrion outer membrane, Peroxisome membrane
Low tissue specificity
{'Ciliated cells': '194.7', 'Basal respiratory cells': '151.2', 'Club cells': '175.9', 'Ionocytes': '107.1', 'Mucus glandular cells': '133.0', 'Serous glandular cells': '230.9', 'Gastric mucus-secreting cells': '110.2', 'Proximal enterocytes': '605.6', 'Paneth cells': '390.1', 'Distal enterocytes': '366.0', 'Intestinal goblet cells': '246.3', 'Exocrine glandular cells': '-0.668', 'Basal prostatic cells': '194.5', 'Prostatic glandular cells': '225.4', 'Breast glandular cells': '-0.106', 'Breast myoepithelial cells': '-0.243', 'Glandular and luminal cells': '148.6', 'Secretory cells': '347.6', 'Basal keratinocytes': '134.7', 'Suprabasal keratinocytes': '247.4', 'Basal squamous epithelial cells': '136.1', 'Squamous epithelial cells': '199.9', 'Alveolar cells type 1': '0.168', 'Alveolar cells type 2': '-0.084', 'Salivary duct cells': '132.3', 'Ductal cells': '0.483', 'Hepatocytes': '0.355', 'Cholangiocytes': '213.7', 'Proximal tubular cells': '0.213', 'Distal tubular cells': '562.4', 'Collecting duct cells': '192.5', 'Mesothelial cells': '0.310', 'Sertoli cells': '-0.291', 'Granulosa cells': '143.0', 'Enteroendocrine cells': '256.5', 'Pancreatic endocrine cells': '256.4', 'Leydig cells': '-0.355', 'Excitatory neurons': '13.2', 'Inhibitory neurons': '12.7', 'Cone photoreceptor cells': '54.4', 'Rod photoreceptor cells': '36.6', 'Bipolar cells': '47.0', 'Horizontal cells': '24.5', 'Astrocytes': '15.2', 'Oligodendrocyte precursor cells': '6.1', 'Oligodendrocytes': '77.4', 'Microglial cells': '14.3', 'Muller glia cells': '262.0', 'Schwann cells': '0.101', 'Spermatogonia': '-0.223', 'Spermatocytes': '-0.154', 'Early spermatids': '0.388', 'Late spermatids': '0.444', 'Oocytes': '61.8', 'Cytotrophoblasts': '271.1', 'Syncytiotrophoblasts': '342.8', 'Extravillous trophoblasts': '347.1', 'Endothelial cells': '213.2', 'Lymphatic endothelial cells': '137.2', 'Cardiomyocytes': '0.693', 'Skeletal myocytes': '0.101', 'Smooth muscle cells': '216.5', 'Adipocytes': '290.2', 'Melanocytes': '0.125', 'Fibroblasts': '185.2', 'Peritubular cells': '-0.238', 'Endometrial stromal cells': '128.1', 'Ovarian stromal cells': '185.1', 'Undifferentiated cells': '209.6', 'T-cells': '118.3', 'B-cells': '95.0', 'Plasma cells': '203.0', 'Nk-cells': '127.7', 'Granulocytes': '226.4', 'Monocytes': '124.2', 'Macrophages': '133.2', 'Hofbauer cells': '302.4', 'Kupffer cells': '144.4', 'Dendritic cells': '95.1', 'Langerhans cells': '0.211', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '0.384', 'Adipocytes (Visceral)': '0.298', 'Breast glandular cells (progenitors)': '-0.159', 'Adipocytes (Breast)': '0.424', 'Colon enterocytes': '-0.341', 'Colon enteroendocrine cells': '0.157', 'Enteric glia cells': '0.368', 'Mitotic cells (Colon)': '-0.369', 'Mitotic cells (Heart)': '0.358', 'Podocytes': '0.049', 'Ascending Loop of Henle cells': '0.401', 'Intercalated cells': '0.111', 'Cholangiocyte': '0.318', 'NK-cells (Liver)': '-0.233', 'Respiratory ciliated cells': '0.016', 'Mitotic cells (Lung)': '-0.041', 'NK-cells (Lung)': '-0.089', 'B-cells (Lung)': '-0.263', 'Alpha cells': '0.340', 'Beta cells': '0.204', 'Prostate glandular cells': '0.156', 'Prostate basal glandular cells': '-0.033', 'Urothelial cells': '-0.203', 'Keratinocyte (other)': '0.156', 'Keratinocyte (granular)': '0.121', 'Hair cortex cells': '0.059', 'Inner root sheath cells': '0.017', 'Outer root sheath cells': '0.049', 'Sebaceous gland cells': '0.013', 'Eccrine sweat gland cells': '-0.228', 'Adipocytes (Skin)': '-0.102', 'Mitotic cells (Skin)': '0.011', 'Parietal cells': '-0.580', 'Chief cells': '-0.406', 'Gastric mucous cells': '-0.507', 'Gastric enteroendocrine cells': '-0.437', 'Mitotic cells (Stomach)': '-0.155', 'Parafollicular cells': '0.123', 'Thyroid glandular cells': '0.466', 'Mitotic cells (Thyroid)': '-0.124', 'Adrenal cortex cells': '0.252', 'Adrenal medulla cells': '0.011', 'Mitotic cells (Adrenal gland)': '0.061', 'Minor salivary glandular cells': '0.341', 'Minor salivary gland ductal cells': '-0.035', 'Minor salivary gland basal cells': '0.202', 'Mitotic cells (Minor salivary gland)': '0.272', 'Adipocytes (Minor salivary gland)': '0.205', 'Somatotropes': '0.250', 'Lactotropes': '0.256', 'Gonadotropes': '0.031', 'Corticotropes': '0.124', 'Thyrotropes': '0.193', 'Undifferentiated cells (Pituitary gland)': '-0.011', 'Mitotic cells (Spleen)': '-0.479', 'Platelets': '-0.223', 'Erythrocytes': '-0.096', 'Hematopoietic stem cells': '-0.251', 'B-cells (Spleen)': '0.169', 'NK-cells (Spleen)': '0.142', 'Amygdala excitatory': '16.3', 'Cerebellar inhibitory': '28.3', 'Cge interneuron': '35.6', 'Deep-layer corticothalamic and 6b': '26.3', 'Deep-layer intratelencephalic': '28.2', 'Deep-layer near-projecting': '34.3', 'Eccentric medium spiny neuron': '20.8', 'Hippocampal ca1-3': '21.7', 'Hippocampal ca4': '58.7', 'Hippocampal dentate gyrus': '32.1', 'Lamp5-lhx6 and chandelier': '33.1', 'Lower rhombic lip': '44.3', 'Mammillary body': '21.3', 'Medium spiny neuron': '19.7', 'Mge interneuron': '25.3', 'Midbrain-derived inhibitory': '31.3', 'Miscellaneous': '36.1', 'Splatter': '31.5', 'Thalamic excitatory': '36.1', 'Upper rhombic lip': '36.9', 'Upper-layer intratelencephalic': '28.6', 'Astrocyte': '26.1', 'Bergmann glia': '52.2', 'Central nervous system macrophage': '32.2', 'Choroid plexus epithelial cell': '45.0', 'Committed oligodendrocyte precursor': '64.5', 'Ependymal cell': '34.5', 'Oligodendrocyte': '190.2', 'Oligodendrocyte precursor cell': '33.5', 'Endothelial cell': '50.8', 'Pericyte': '55.8', 'Vascular associated smooth muscle cell': '72.1', 'Fibroblast': '34.5', 'Leukocyte': '43.4', 'Basophil': '53.3', 'Eosinophil': '136.2', 'Neutrophil': '48.8', 'Classical monocyte': '59.9', 'Non-classical monocyte': '53.2', 'Intermediate monocyte': '67.9', 'T-reg': '62.4', 'GdT-cell': '122.5', 'MAIT T-cell': '59.6', 'Memory CD4 T-cell': '115.8', 'Naive CD4 T-cell': '67.6', 'Memory CD8 T-cell': '115.9', 'Naive CD8 T-cell': '83.6', 'Memory B-cell': '153.3', 'Naive B-cell': '50.3', 'Plasmacytoid DC': '60.3', 'Myeloid DC': '62.4', 'NK-cell': '86.3', 'Total PBMC': '59.5', 'Vd2 gdTCR': '84.6', 'Memory CD4 T-cell TFH': '112.0', 'Memory CD4 T-cell Th2': '91.7', 'Memory CD4 T-cell Th17': '89.0', 'Memory CD4 T-cell Th1\\/Th17': '66.1', 'Non-Vd2 gdTCR': '58.3', 'Memory CD4 T-cell Th1': '95.0', 'Terminal effector memory CD4 T-cell': '45.9', 'Central memory CD8 T-cell': '51.8', 'Effector memory CD8 T-cell': '41.4', 'Terminal effector memory CD8 T-cell': '76.2', 'Switched memory B-cell': '47.7', 'Plasmablast': '77.7', 'Non-switched memory B-cell': '49.9', 'Exhausted memory B-cell': '66.5', 'Progenitor cell': '55.6', 'Naive CD4 T-cell activated': '55.1', 'Naive CD8 T-cell activated': '72.8', 'Memory T-reg': '120.8', 'Naive T-reg': '85.5'}
1NZN, 1PC2, 7YA9, 7YKA, 8XWX
{'Adipose Tissue': 126.1198338870432, 'Adrenal Gland': 112.19755813953488, 'Bladder': 113.18, 'Blood': 58.71327233584499, 'Blood Vessel': 146.74393258426966, 'Brain': 107.77417865253597, 'Breast': 126.08357298474944, 'Cervix Uteri': 122.9242105263158, 'Colon': 111.1749293966624, 'Esophagus': 109.73071280276817, 'Fallopian Tube': 137.94444444444446, 'Heart': 87.63152613240419, 'Kidney': 94.79741573033706, 'Liver': 72.63318584070795, 'Lung': 105.8540311418685, 'Muscle': 129.90854296388542, 'Nerve': 177.52042003231017, 'Ovary': 119.08938888888888, 'Pancreas': 50.02582317073171, 'Pituitary': 143.43985865724383, 'Prostate': 112.46065306122448, 'Salivary Gland': 79.91969135802469, 'Skin': 101.94566611387506, 'Small Intestine': 86.24106951871657, 'Spleen': 105.80489626556016, 'Stomach': 93.3832590529248, 'Testis': 128.3001939058172, 'Thyroid': 144.65782542113325, 'Uterus': 147.92704225352114, 'Vagina': 104.02576923076924}
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[49.65, 44.54, 48.56, 50.92, 52.7, 54.58, 58.61, 62.04, 64.88, 69.69, 72.31, 75.3, 78.2, 80.87, 82.12, 86.44, 86.89, 86.16, 89.1, 88.98, 88.3, 88.52, 89.19, 88.37, 86.14, 86.69, 87.31, 83.76, 81.25, 86.62, 87.11, 87.57, 86.73, 88.35, 90.26, 90.77, 88.97, 90.38, 91.16, 88.7, 88.86, 89.21, 89.22, 85.11, 84.09, 80.83, 85.77, 88.45, 90.37, 89.16, 91.21, 93.21, 92.42, 93.56, 94.09, 94.29, 92.68, 93.23, 92.62, 91.04, 89.28, 88.6, 88.57, 87.33, 82.8, 87.2, 85.08, 84.76, 87.38, 87.39, 88.47, 88.96, 91.93, 92.14, 91.25, 91.42, 94.01, 92.37, 91.61, 92.28, 93.18, 91.0, 87.4, 90.35, 88.0, 89.42, 89.52, 87.81, 90.43, 91.41, 90.49, 91.95, 91.59, 91.46, 90.3, 88.98, 88.04, 89.04, 87.73, 83.59, 85.66, 83.5, 84.75, 84.18, 86.97, 85.37, 86.88, 89.57, 89.71, 89.12, 91.2, 90.03, 88.93, 89.43, 87.91, 86.89, 85.53, 83.76, 81.14, 81.45, 76.39, 68.78, 62.24, 56.62, 52.32, 56.2, 55.77, 54.35, 54.59, 45.6, 46.32, 45.88, 51.95, 54.46, 45.77, 51.1, 47.26, 44.34, 45.59, 50.14, 44.6, 49.17, 54.48, 47.29, 50.78, 52.85, 53.7, 47.28, 43.41, 43.62, 38.56, 45.06]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
78.165
0.449013
2,885
O60260
Q9Y3E5
33082525, 23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
PTRH2
MPSKSLVMEYLAHPSTLGLAVGVACGMCLGWSLRVCFGMLPKSKTSKTHTDTESEASILGDSGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKLY
Homo sapiens
Mitochondrion outer membrane
Low tissue specificity
{'Ciliated cells': '22.4', 'Basal respiratory cells': '47.0', 'Club cells': '24.9', 'Ionocytes': '30.2', 'Mucus glandular cells': '14.9', 'Serous glandular cells': '15.8', 'Gastric mucus-secreting cells': '16.5', 'Proximal enterocytes': '10.3', 'Paneth cells': '12.2', 'Distal enterocytes': '10.0', 'Intestinal goblet cells': '10.5', 'Exocrine glandular cells': '-0.748', 'Basal prostatic cells': '14.4', 'Prostatic glandular cells': '20.4', 'Breast glandular cells': '0.255', 'Breast myoepithelial cells': '0.056', 'Glandular and luminal cells': '25.9', 'Secretory cells': '43.6', 'Basal keratinocytes': '31.8', 'Suprabasal keratinocytes': '31.8', 'Basal squamous epithelial cells': '23.7', 'Squamous epithelial cells': '20.4', 'Alveolar cells type 1': '-0.113', 'Alveolar cells type 2': '0.265', 'Salivary duct cells': '11.3', 'Ductal cells': '0.515', 'Hepatocytes': '0.233', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.245', 'Distal tubular cells': '3.1', 'Collecting duct cells': '11.7', 'Mesothelial cells': '-0.079', 'Sertoli cells': '0.396', 'Granulosa cells': '16.1', 'Enteroendocrine cells': '14.5', 'Pancreatic endocrine cells': '22.1', 'Leydig cells': '0.251', 'Excitatory neurons': '9.4', 'Inhibitory neurons': '8.7', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '2.2', 'Bipolar cells': '3.6', 'Horizontal cells': '2.5', 'Astrocytes': '5.3', 'Oligodendrocyte precursor cells': '7.1', 'Oligodendrocytes': '10.7', 'Microglial cells': '2.7', 'Muller glia cells': '7.7', 'Schwann cells': '-0.013', 'Spermatogonia': '0.095', 'Spermatocytes': '0.117', 'Early spermatids': '-0.008', 'Late spermatids': '-0.353', 'Oocytes': '7.4', 'Cytotrophoblasts': '27.7', 'Syncytiotrophoblasts': '35.8', 'Extravillous trophoblasts': '26.7', 'Endothelial cells': '20.3', 'Lymphatic endothelial cells': '17.8', 'Cardiomyocytes': '0.442', 'Skeletal myocytes': '-0.302', 'Smooth muscle cells': '17.9', 'Adipocytes': '19.3', 'Melanocytes': '-0.036', 'Fibroblasts': '24.1', 'Peritubular cells': '0.188', 'Endometrial stromal cells': '34.0', 'Ovarian stromal cells': '16.7', 'Undifferentiated cells': '18.5', 'T-cells': '11.8', 'B-cells': '16.2', 'Plasma cells': '27.8', 'Nk-cells': '12.0', 'Granulocytes': '27.0', 'Monocytes': '35.3', 'Macrophages': '14.7', 'Hofbauer cells': '15.0', 'Kupffer cells': '11.1', 'Dendritic cells': '12.3', 'Langerhans cells': '-0.004', 'Erythroid cells': '-0.125', 'Adipocytes (Subcutaneous)': '0.112', 'Adipocytes (Visceral)': '0.112', 'Breast glandular cells (progenitors)': '0.165', 'Adipocytes (Breast)': '-0.065', 'Colon enterocytes': '0.169', 'Colon enteroendocrine cells': '0.024', 'Enteric glia cells': '-0.430', 'Mitotic cells (Colon)': '0.163', 'Mitotic cells (Heart)': '0.433', 'Podocytes': '-0.141', 'Ascending Loop of Henle cells': '0.271', 'Intercalated cells': '-0.121', 'Cholangiocyte': '0.290', 'NK-cells (Liver)': '-0.347', 'Respiratory ciliated cells': '-0.141', 'Mitotic cells (Lung)': '0.112', 'NK-cells (Lung)': '-0.192', 'B-cells (Lung)': '-0.215', 'Alpha cells': '0.343', 'Beta cells': '0.199', 'Prostate glandular cells': '0.256', 'Prostate basal glandular cells': '0.390', 'Urothelial cells': '0.174', 'Keratinocyte (other)': '-0.142', 'Keratinocyte (granular)': '0.015', 'Hair cortex cells': '0.015', 'Inner root sheath cells': '0.079', 'Outer root sheath cells': '-0.048', 'Sebaceous gland cells': '0.122', 'Eccrine sweat gland cells': '0.038', 'Adipocytes (Skin)': '0.099', 'Mitotic cells (Skin)': '-0.075', 'Parietal cells': '-0.404', 'Chief cells': '-0.249', 'Gastric mucous cells': '-0.083', 'Gastric enteroendocrine cells': '-0.143', 'Mitotic cells (Stomach)': '0.270', 'Parafollicular cells': '0.020', 'Thyroid glandular cells': '0.309', 'Mitotic cells (Thyroid)': '-0.044', 'Adrenal cortex cells': '0.455', 'Adrenal medulla cells': '0.003', 'Mitotic cells (Adrenal gland)': '0.088', 'Minor salivary glandular cells': '0.565', 'Minor salivary gland ductal cells': '0.066', 'Minor salivary gland basal cells': '0.237', 'Mitotic cells (Minor salivary gland)': '0.236', 'Adipocytes (Minor salivary gland)': '0.100', 'Somatotropes': '0.149', 'Lactotropes': '-0.122', 'Gonadotropes': '-0.166', 'Corticotropes': '-0.037', 'Thyrotropes': '-0.116', 'Undifferentiated cells (Pituitary gland)': '0.006', 'Mitotic cells (Spleen)': '-0.047', 'Platelets': '0.014', 'Erythrocytes': '-0.141', 'Hematopoietic stem cells': '-0.156', 'B-cells (Spleen)': '0.348', 'NK-cells (Spleen)': '0.146', 'Amygdala excitatory': '28.4', 'Cerebellar inhibitory': '27.2', 'Cge interneuron': '29.9', 'Deep-layer corticothalamic and 6b': '28.8', 'Deep-layer intratelencephalic': '30.9', 'Deep-layer near-projecting': '33.3', 'Eccentric medium spiny neuron': '34.3', 'Hippocampal ca1-3': '27.6', 'Hippocampal ca4': '41.8', 'Hippocampal dentate gyrus': '50.5', 'Lamp5-lhx6 and chandelier': '28.9', 'Lower rhombic lip': '42.5', 'Mammillary body': '40.7', 'Medium spiny neuron': '40.4', 'Mge interneuron': '27.1', 'Midbrain-derived inhibitory': '32.9', 'Miscellaneous': '31.9', 'Splatter': '30.1', 'Thalamic excitatory': '26.7', 'Upper rhombic lip': '39.0', 'Upper-layer intratelencephalic': '34.8', 'Astrocyte': '32.0', 'Bergmann glia': '41.4', 'Central nervous system macrophage': '52.0', 'Choroid plexus epithelial cell': '29.4', 'Committed oligodendrocyte precursor': '39.2', 'Ependymal cell': '22.8', 'Oligodendrocyte': '61.2', 'Oligodendrocyte precursor cell': '43.4', 'Endothelial cell': '29.3', 'Pericyte': '21.5', 'Vascular associated smooth muscle cell': '22.0', 'Fibroblast': '28.6', 'Leukocyte': '34.3', 'Basophil': '6.2', 'Eosinophil': '2.9', 'Neutrophil': '18.9', 'Classical monocyte': '5.3', 'Non-classical monocyte': '8.0', 'Intermediate monocyte': '22.3', 'T-reg': '14.7', 'GdT-cell': '22.7', 'MAIT T-cell': '13.4', 'Memory CD4 T-cell': '26.4', 'Naive CD4 T-cell': '8.5', 'Memory CD8 T-cell': '25.7', 'Naive CD8 T-cell': '8.4', 'Memory B-cell': '43.3', 'Naive B-cell': '10.6', 'Plasmacytoid DC': '24.7', 'Myeloid DC': '15.1', 'NK-cell': '7.8', 'Total PBMC': '21.3', 'Vd2 gdTCR': '14.0', 'Memory CD4 T-cell Th1\\/Th17': '7.8', 'Memory CD4 T-cell Th17': '7.3', 'Memory CD4 T-cell Th2': '7.4', 'Non-Vd2 gdTCR': '12.6', 'Memory CD4 T-cell Th1': '7.0', 'Memory CD4 T-cell TFH': '6.7', 'Terminal effector memory CD4 T-cell': '9.4', 'Central memory CD8 T-cell': '13.9', 'Effector memory CD8 T-cell': '9.6', 'Terminal effector memory CD8 T-cell': '13.8', 'Non-switched memory B-cell': '15.9', 'Plasmablast': '20.9', 'Switched memory B-cell': '17.7', 'Exhausted memory B-cell': '22.6', 'Progenitor cell': '18.4', 'Memory T-reg': '6.3', 'Naive CD4 T-cell activated': '76.1', 'Naive CD8 T-cell activated': '67.8', 'Naive T-reg': '9.1'}
1Q7S
{'Adipose Tissue': 7.598124584717608, 'Adrenal Gland': 8.296988372093024, 'Bladder': 6.516047619047619, 'Blood': 5.035221313240043, 'Blood Vessel': 4.943240449438202, 'Brain': 4.804685541256624, 'Breast': 7.433806100217866, 'Cervix Uteri': 7.094105263157895, 'Colon': 6.324406931964056, 'Esophagus': 5.9301432525951565, 'Fallopian Tube': 7.720888888888889, 'Heart': 2.5067881533101044, 'Kidney': 3.7183932584269663, 'Liver': 5.782358407079647, 'Lung': 6.8572508650519035, 'Muscle': 4.316973848069739, 'Nerve': 7.534991922455573, 'Ovary': 7.874477777777778, 'Pancreas': 3.4725963414634147, 'Pituitary': 7.862243816254416, 'Prostate': 7.364942857142857, 'Salivary Gland': 6.013327160493827, 'Skin': 9.54554284134881, 'Small Intestine': 6.4003315508021394, 'Spleen': 8.879439834024897, 'Stomach': 5.5013796657381615, 'Testis': 10.80591135734072, 'Thyroid': 6.581261868300154, 'Uterus': 7.569753521126761, 'Vagina': 5.930371794871795}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
84.06743
0.467207
2,805
O60260
Q9Y3U8
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
RPL36
MALRYPMAVGLNKGHKVTKNVSKPRHSRRRGRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKKRVGTHIRAKRKREELSNVLAAMRKAAAKKD
Homo sapiens
Cytoplasm, cytosol, Cytoplasm
Low tissue specificity
{'Ciliated cells': '1187.0', 'Basal respiratory cells': '3916.5', 'Club cells': '1917.2', 'Ionocytes': '1768.6', 'Mucus glandular cells': '1527.3', 'Serous glandular cells': '3580.3', 'Gastric mucus-secreting cells': '2008.6', 'Proximal enterocytes': '3492.9', 'Paneth cells': '4224.9', 'Distal enterocytes': '2959.5', 'Intestinal goblet cells': '5503.9', 'Exocrine glandular cells': '-0.679', 'Basal prostatic cells': '2229.9', 'Prostatic glandular cells': '2424.6', 'Breast glandular cells': '0.587', 'Breast myoepithelial cells': '0.451', 'Glandular and luminal cells': '2232.7', 'Secretory cells': '4368.0', 'Basal keratinocytes': '5315.5', 'Suprabasal keratinocytes': '7365.9', 'Basal squamous epithelial cells': '4662.8', 'Squamous epithelial cells': '4928.2', 'Alveolar cells type 1': '-0.214', 'Alveolar cells type 2': '-0.340', 'Salivary duct cells': '1684.7', 'Ductal cells': '0.533', 'Hepatocytes': '0.009', 'Cholangiocytes': '1740.0', 'Proximal tubular cells': '0.167', 'Distal tubular cells': '3239.4', 'Collecting duct cells': '1295.3', 'Mesothelial cells': '0.354', 'Sertoli cells': '0.406', 'Granulosa cells': '4144.1', 'Enteroendocrine cells': '3068.5', 'Pancreatic endocrine cells': '4374.0', 'Leydig cells': '0.440', 'Excitatory neurons': '11.0', 'Inhibitory neurons': '11.8', 'Cone photoreceptor cells': '317.7', 'Rod photoreceptor cells': '213.9', 'Bipolar cells': '226.8', 'Horizontal cells': '81.2', 'Astrocytes': '14.6', 'Oligodendrocyte precursor cells': '9.4', 'Oligodendrocytes': '17.1', 'Microglial cells': '25.0', 'Muller glia cells': '875.1', 'Schwann cells': '-0.052', 'Spermatogonia': '0.132', 'Spermatocytes': '-0.356', 'Early spermatids': '-0.447', 'Late spermatids': '-0.378', 'Oocytes': '5587.0', 'Cytotrophoblasts': '2781.7', 'Syncytiotrophoblasts': '2458.2', 'Extravillous trophoblasts': '4546.6', 'Endothelial cells': '2325.6', 'Lymphatic endothelial cells': '2610.2', 'Cardiomyocytes': '0.377', 'Skeletal myocytes': '-0.221', 'Smooth muscle cells': '1999.6', 'Adipocytes': '2284.9', 'Melanocytes': '-0.024', 'Fibroblasts': '1964.9', 'Peritubular cells': '0.391', 'Endometrial stromal cells': '3040.5', 'Ovarian stromal cells': '7114.1', 'Undifferentiated cells': '5423.6', 'T-cells': '3125.7', 'B-cells': '4059.5', 'Plasma cells': '2508.8', 'Nk-cells': '2021.7', 'Granulocytes': '2340.1', 'Monocytes': '2716.2', 'Macrophages': '2006.4', 'Hofbauer cells': '2802.9', 'Kupffer cells': '3211.5', 'Dendritic cells': '1743.3', 'Langerhans cells': '0.052', 'Erythroid cells': '-0.101', 'Adipocytes (Subcutaneous)': '-0.293', 'Adipocytes (Visceral)': '-0.301', 'Breast glandular cells (progenitors)': '0.502', 'Adipocytes (Breast)': '-0.544', 'Colon enterocytes': '-0.231', 'Colon enteroendocrine cells': '0.087', 'Enteric glia cells': '0.435', 'Mitotic cells (Colon)': '-0.074', 'Mitotic cells (Heart)': '0.410', 'Podocytes': '0.048', 'Ascending Loop of Henle cells': '0.279', 'Intercalated cells': '0.045', 'Cholangiocyte': '0.334', 'NK-cells (Liver)': '-0.282', 'Respiratory ciliated cells': '0.031', 'Mitotic cells (Lung)': '-0.024', 'NK-cells (Lung)': '-0.100', 'B-cells (Lung)': '-0.015', 'Alpha cells': '0.224', 'Beta cells': '0.095', 'Prostate glandular cells': '0.189', 'Prostate basal glandular cells': '0.237', 'Urothelial cells': '0.232', 'Keratinocyte (other)': '0.286', 'Keratinocyte (granular)': '-0.015', 'Hair cortex cells': '-0.231', 'Inner root sheath cells': '-0.175', 'Outer root sheath cells': '-0.205', 'Sebaceous gland cells': '-0.161', 'Eccrine sweat gland cells': '-0.353', 'Adipocytes (Skin)': '-0.324', 'Mitotic cells (Skin)': '-0.126', 'Parietal cells': '-0.566', 'Chief cells': '-0.288', 'Gastric mucous cells': '-0.311', 'Gastric enteroendocrine cells': '-0.205', 'Mitotic cells (Stomach)': '0.024', 'Parafollicular cells': '0.021', 'Thyroid glandular cells': '0.128', 'Mitotic cells (Thyroid)': '0.016', 'Adrenal cortex cells': '0.170', 'Adrenal medulla cells': '-0.062', 'Mitotic cells (Adrenal gland)': '-0.336', 'Minor salivary glandular cells': '0.392', 'Minor salivary gland ductal cells': '0.059', 'Minor salivary gland basal cells': '0.193', 'Mitotic cells (Minor salivary gland)': '0.121', 'Adipocytes (Minor salivary gland)': '0.161', 'Somatotropes': '0.163', 'Lactotropes': '-0.075', 'Gonadotropes': '-0.266', 'Corticotropes': '-0.143', 'Thyrotropes': '-0.080', 'Undifferentiated cells (Pituitary gland)': '0.110', 'Mitotic cells (Spleen)': '-0.362', 'Platelets': '-0.305', 'Erythrocytes': '-0.192', 'Hematopoietic stem cells': '-0.230', 'B-cells (Spleen)': '0.522', 'NK-cells (Spleen)': '0.142', 'Amygdala excitatory': '51.7', 'Cerebellar inhibitory': '65.6', 'Cge interneuron': '81.0', 'Deep-layer corticothalamic and 6b': '56.5', 'Deep-layer intratelencephalic': '63.4', 'Deep-layer near-projecting': '55.9', 'Eccentric medium spiny neuron': '38.1', 'Hippocampal ca1-3': '42.2', 'Hippocampal ca4': '142.1', 'Hippocampal dentate gyrus': '104.4', 'Lamp5-lhx6 and chandelier': '64.9', 'Lower rhombic lip': '69.9', 'Mammillary body': '28.2', 'Medium spiny neuron': '46.5', 'Mge interneuron': '51.0', 'Midbrain-derived inhibitory': '47.6', 'Miscellaneous': '65.9', 'Splatter': '62.6', 'Thalamic excitatory': '48.4', 'Upper rhombic lip': '100.7', 'Upper-layer intratelencephalic': '67.1', 'Astrocyte': '44.1', 'Bergmann glia': '63.0', 'Central nervous system macrophage': '116.7', 'Choroid plexus epithelial cell': '148.3', 'Committed oligodendrocyte precursor': '90.1', 'Ependymal cell': '97.4', 'Oligodendrocyte': '85.1', 'Oligodendrocyte precursor cell': '60.0', 'Endothelial cell': '184.5', 'Pericyte': '121.7', 'Vascular associated smooth muscle cell': '187.8', 'Fibroblast': '111.7', 'Leukocyte': '204.8', 'Basophil': '56.8', 'Eosinophil': '431.1', 'Neutrophil': '14.9', 'Classical monocyte': '181.6', 'Non-classical monocyte': '115.7', 'Intermediate monocyte': '175.0', 'T-reg': '273.9', 'GdT-cell': '1243.6', 'MAIT T-cell': '208.1', 'Memory CD4 T-cell': '2394.3', 'Naive CD4 T-cell': '387.8', 'Memory CD8 T-cell': '1781.7', 'Naive CD8 T-cell': '589.3', 'Memory B-cell': '2503.6', 'Naive B-cell': '225.5', 'Plasmacytoid DC': '133.6', 'Myeloid DC': '245.8', 'NK-cell': '175.9', 'Total PBMC': '182.3', 'Vd2 gdTCR': '292.5', 'Memory CD4 T-cell Th1\\/Th17': '465.2', 'Memory CD4 T-cell Th17': '653.0', 'Memory CD4 T-cell Th2': '658.9', 'Non-Vd2 gdTCR': '141.7', 'Memory CD4 T-cell Th1': '695.9', 'Memory CD4 T-cell TFH': '1027.9', 'Terminal effector memory CD4 T-cell': '180.7', 'Central memory CD8 T-cell': '290.9', 'Effector memory CD8 T-cell': '135.6', 'Terminal effector memory CD8 T-cell': '178.2', 'Non-switched memory B-cell': '241.2', 'Plasmablast': '261.2', 'Switched memory B-cell': '214.0', 'Exhausted memory B-cell': '328.7', 'Progenitor cell': '177.4', 'Naive CD4 T-cell activated': '373.3', 'Naive CD8 T-cell activated': '446.2', 'Memory T-reg': '742.9', 'Naive T-reg': '704.8'}
4UG0, 4V6X, 5AJ0, 5LKS, 5T2C, 6IP5, 6IP6, 6IP8, 6LQM, 6LSR, 6LSS, 6LU8, 6OLE, 6OLF, 6OLG, 6OLI, 6OLZ, 6OM0, 6OM7, 6QZP, 6W6L, 6XA1, 6Y0G, 6Y2L, 6Y57, 6Y6X, 6Z6L, 6Z6M, 6Z6N, 6ZM7, 6ZME, 6ZMI, 6ZMO, 7BHP, 7F5S, 7OW7, 7QGG, 7QVP, 7XNX, 7XNY, 8A3D, 8FKP, 8FKQ, 8FKR, 8FKS, 8FKT, 8FKU, 8FKV, 8FKW, 8FKX, 8FKY, 8FKZ, 8FL2, 8FL3, 8FL4, 8FL6, 8FL7, 8FL9, 8FLA, 8FLB, 8FLC, 8FLD, 8FLE, 8FLF, 8G5Y, 8G5Z, 8G60, 8G61, 8G6J, 8GLP, 8IDT, 8IDY, 8IE3, 8IFD, 8IFE, 8INE, 8INF, 8INK, 8IPD, 8IPX, 8IPY, 8IR1, 8IR3, 8JDJ, 8JDK, 8JDL, 8JDM, 8OHD, 8OJ0, 8OJ5, 8OJ8, 8QFD, 8Y0W, 8Y0X
{'Adipose Tissue': 518.3076411960133, 'Adrenal Gland': 636.6313953488371, 'Bladder': 575.7285714285714, 'Blood': 380.8985145317546, 'Blood Vessel': 473.9516104868914, 'Brain': 211.95141937925817, 'Breast': 652.3450980392157, 'Cervix Uteri': 905.0315789473684, 'Colon': 443.97291399229783, 'Esophagus': 517.0654671280276, 'Fallopian Tube': 766.411111111111, 'Heart': 170.82853658536584, 'Kidney': 281.0101123595506, 'Liver': 179.30402654867257, 'Lung': 445.73079584775087, 'Muscle': 208.50302615193024, 'Nerve': 518.2006462035541, 'Ovary': 1657.79, 'Pancreas': 452.72195121951216, 'Pituitary': 474.80388692579504, 'Prostate': 687.2530612244898, 'Salivary Gland': 510.2481481481481, 'Skin': 879.0908789386401, 'Small Intestine': 465.29732620320857, 'Spleen': 552.9307053941908, 'Stomach': 419.0055710306407, 'Testis': 250.10138504155125, 'Thyroid': 439.1676875957121, 'Uterus': 728.7056338028169, 'Vagina': 752.6826923076923}
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[58.62, 79.68, 77.7, 81.03, 82.95, 85.13, 88.08, 89.69, 92.38, 91.05, 91.25, 87.54, 90.65, 89.52, 90.33, 88.81, 91.75, 93.41, 92.68, 91.57, 91.27, 92.42, 93.17, 94.06, 95.39, 95.57, 96.24, 94.77, 93.62, 94.98, 92.59, 94.58, 94.59, 96.63, 97.4, 97.27, 96.4, 96.35, 96.85, 96.92, 96.22, 94.65, 96.29, 96.35, 95.12, 93.97, 96.97, 96.23, 94.08, 95.35, 95.66, 97.26, 96.61, 95.87, 96.01, 96.59, 96.89, 96.28, 95.94, 96.52, 95.83, 95.01, 95.18, 93.09, 95.58, 94.62, 96.37, 96.57, 96.94, 97.05, 97.45, 97.26, 97.42, 97.78, 97.01, 96.75, 95.4, 96.17, 97.54, 97.21, 97.67, 97.25, 97.71, 97.69, 96.91, 97.19, 95.86, 95.98, 95.58, 96.31, 95.3, 95.21, 94.71, 94.65, 94.6, 93.99, 93.29, 93.09, 94.22, 93.53, 93.59, 93.58, 90.4, 75.77, 52.46]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
93.30019
0.569238
2,981
O60260
Q9Y4C2
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
TCAF1
MATPSAAFEALMNGVTSWDVPEDAVPCELLLIGEASFPVMVNDMGQVLIAASSYGRGRLVVVSHEDYLVEAQLTPFLLNAVGWLCSSPGAPIGVHPSLAPLAKILEGSGVDAKVEPEVKDSLGVYCIDAYNETMTEKLVKFMKCGGGLLIGGQAWDWANQGEDERVLFTFPGNLVTSVAGIYFTDNKGDTSFFKVSKKMPKIPVLVSCEDDLSDDREELLHGISELDISNSDCFPSQLLVHGALAFPLGLDSYHGCVIAAARYGRGRVVVTGHKVLFTVGKLGPFLLNAVRWLDGGRRGKVVVQTELRTLSGLLAVGGIDTSIEPNLTSDASVYCFEPVSEVGVKELQEFVAEGGGLFVGAQAWWWAFKNPGVSPLARFPGNLLLNPFGISITSQSLNPGPFRTPKAGIRTYHFRSTLAEFQVIMGRKRGNVEKGWLAKLGPDGAAFLQIPAEEIPAYMSVHRLLRKLLSRYRLPVATRENPVINDCCRGAMLSLATGLAHSGSDLSLLVPEIEDMYSSPYLRPSESPITVEVNCTNPGTRYCWMSTGLYIPGRQIIEVSLPEAAASADLKIQIGCHTDDLTRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPVTVKGAVHAPYYKLGETTLEEWKRRIQENPGPWGELATDNIILTVPTANLRTLENPEPLLRLWDEVMQAVARLGAEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPNVKNWNAWTALETYLQLQEAFGWEPFIRLFTEYRNQTNLPTENVDKMNLWVKMFSHQVQKNLAPFFEAWAWPIQKEVATSLAYLPEWKENIMKLYLLTQMPH
Homo sapiens
Cell membrane
Low tissue specificity
{'Ciliated cells': '18.6', 'Basal respiratory cells': '17.9', 'Club cells': '25.1', 'Ionocytes': '12.1', 'Mucus glandular cells': '34.8', 'Serous glandular cells': '25.8', 'Gastric mucus-secreting cells': '18.9', 'Proximal enterocytes': '17.7', 'Paneth cells': '19.4', 'Distal enterocytes': '26.0', 'Intestinal goblet cells': '43.4', 'Exocrine glandular cells': '-0.492', 'Basal prostatic cells': '36.4', 'Prostatic glandular cells': '103.8', 'Breast glandular cells': '0.330', 'Breast myoepithelial cells': '0.402', 'Glandular and luminal cells': '40.0', 'Secretory cells': '26.6', 'Basal keratinocytes': '14.6', 'Suprabasal keratinocytes': '13.6', 'Basal squamous epithelial cells': '13.7', 'Squamous epithelial cells': '13.5', 'Alveolar cells type 1': '0.243', 'Alveolar cells type 2': '-0.347', 'Salivary duct cells': '35.8', 'Ductal cells': '0.558', 'Hepatocytes': '0.608', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.149', 'Distal tubular cells': '3.1', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.334', 'Sertoli cells': '0.499', 'Granulosa cells': '54.1', 'Enteroendocrine cells': '37.8', 'Pancreatic endocrine cells': '22.1', 'Leydig cells': '0.595', 'Excitatory neurons': '68.8', 'Inhibitory neurons': '60.4', 'Cone photoreceptor cells': '28.9', 'Rod photoreceptor cells': '17.6', 'Bipolar cells': '33.1', 'Horizontal cells': '45.3', 'Astrocytes': '28.8', 'Oligodendrocyte precursor cells': '53.8', 'Oligodendrocytes': '40.7', 'Microglial cells': '27.7', 'Muller glia cells': '22.6', 'Schwann cells': '0.103', 'Spermatogonia': '0.625', 'Spermatocytes': '0.375', 'Early spermatids': '-0.291', 'Late spermatids': '-0.620', 'Oocytes': '34.6', 'Cytotrophoblasts': '235.4', 'Syncytiotrophoblasts': '472.8', 'Extravillous trophoblasts': '35.5', 'Endothelial cells': '37.0', 'Lymphatic endothelial cells': '29.2', 'Cardiomyocytes': '0.688', 'Skeletal myocytes': '-0.065', 'Smooth muscle cells': '36.8', 'Adipocytes': '32.4', 'Melanocytes': '0.170', 'Fibroblasts': '40.9', 'Peritubular cells': '0.541', 'Endometrial stromal cells': '58.7', 'Ovarian stromal cells': '41.6', 'Undifferentiated cells': '32.2', 'T-cells': '13.2', 'B-cells': '10.4', 'Plasma cells': '10.3', 'Nk-cells': '13.4', 'Granulocytes': '14.6', 'Monocytes': '4.1', 'Macrophages': '14.0', 'Hofbauer cells': '16.0', 'Kupffer cells': '11.7', 'Dendritic cells': '16.8', 'Langerhans cells': '0.279', 'Erythroid cells': '-0.085', 'Adipocytes (Subcutaneous)': '-0.012', 'Adipocytes (Visceral)': '0.038', 'Breast glandular cells (progenitors)': '0.314', 'Adipocytes (Breast)': '-0.113', 'Colon enterocytes': '-0.154', 'Colon enteroendocrine cells': '0.366', 'Enteric glia cells': '0.122', 'Mitotic cells (Colon)': '-0.046', 'Mitotic cells (Heart)': '0.435', 'Podocytes': '-0.037', 'Ascending Loop of Henle cells': '0.491', 'Intercalated cells': '0.008', 'Cholangiocyte': '0.231', 'NK-cells (Liver)': '-0.263', 'Respiratory ciliated cells': '0.027', 'Mitotic cells (Lung)': '0.019', 'NK-cells (Lung)': '0.286', 'B-cells (Lung)': '0.080', 'Alpha cells': '0.461', 'Beta cells': '0.299', 'Prostate glandular cells': '0.398', 'Prostate basal glandular cells': '0.149', 'Urothelial cells': '-0.068', 'Keratinocyte (other)': '0.002', 'Keratinocyte (granular)': '-0.211', 'Hair cortex cells': '0.158', 'Inner root sheath cells': '0.232', 'Outer root sheath cells': '0.359', 'Sebaceous gland cells': '0.290', 'Eccrine sweat gland cells': '0.310', 'Adipocytes (Skin)': '0.152', 'Mitotic cells (Skin)': '0.456', 'Parietal cells': '-0.511', 'Chief cells': '-0.540', 'Gastric mucous cells': '-0.376', 'Gastric enteroendocrine cells': '-0.384', 'Mitotic cells (Stomach)': '0.027', 'Parafollicular cells': '0.075', 'Thyroid glandular cells': '0.595', 'Mitotic cells (Thyroid)': '0.014', 'Adrenal cortex cells': '0.777', 'Adrenal medulla cells': '0.066', 'Mitotic cells (Adrenal gland)': '0.492', 'Minor salivary glandular cells': '0.434', 'Minor salivary gland ductal cells': '0.255', 'Minor salivary gland basal cells': '0.138', 'Mitotic cells (Minor salivary gland)': '0.199', 'Adipocytes (Minor salivary gland)': '0.180', 'Somatotropes': '0.072', 'Lactotropes': '0.132', 'Gonadotropes': '0.184', 'Corticotropes': '0.201', 'Thyrotropes': '0.351', 'Undifferentiated cells (Pituitary gland)': '0.005', 'Mitotic cells (Spleen)': '-0.210', 'Platelets': '-0.065', 'Erythrocytes': '-0.100', 'Hematopoietic stem cells': '-0.158', 'B-cells (Spleen)': '0.108', 'NK-cells (Spleen)': '0.218', 'Amygdala excitatory': '65.1', 'Cerebellar inhibitory': '68.8', 'Cge interneuron': '52.2', 'Deep-layer corticothalamic and 6b': '50.4', 'Deep-layer intratelencephalic': '55.3', 'Deep-layer near-projecting': '62.8', 'Eccentric medium spiny neuron': '77.0', 'Hippocampal ca1-3': '56.9', 'Hippocampal ca4': '49.8', 'Hippocampal dentate gyrus': '99.9', 'Lamp5-lhx6 and chandelier': '52.7', 'Lower rhombic lip': '56.7', 'Mammillary body': '49.9', 'Medium spiny neuron': '130.4', 'Mge interneuron': '57.9', 'Midbrain-derived inhibitory': '53.6', 'Miscellaneous': '53.8', 'Splatter': '59.0', 'Thalamic excitatory': '61.9', 'Upper rhombic lip': '65.9', 'Upper-layer intratelencephalic': '53.1', 'Astrocyte': '40.4', 'Bergmann glia': '47.4', 'Central nervous system macrophage': '33.2', 'Choroid plexus epithelial cell': '33.8', 'Committed oligodendrocyte precursor': '37.6', 'Ependymal cell': '30.3', 'Oligodendrocyte': '43.3', 'Oligodendrocyte precursor cell': '59.6', 'Endothelial cell': '40.1', 'Pericyte': '74.7', 'Vascular associated smooth muscle cell': '35.6', 'Fibroblast': '64.6', 'Leukocyte': '26.9', 'Basophil': '4.1', 'Eosinophil': '0.9', 'Neutrophil': '2.5', 'Classical monocyte': '3.2', 'Non-classical monocyte': '4.5', 'Intermediate monocyte': '11.1', 'T-reg': '16.9', 'GdT-cell': '4.7', 'MAIT T-cell': '25.0', 'Memory CD4 T-cell': '2.8', 'Naive CD4 T-cell': '17.9', 'Memory CD8 T-cell': '3.1', 'Naive CD8 T-cell': '17.6', 'Memory B-cell': '1.6', 'Naive B-cell': '15.8', 'Plasmacytoid DC': '20.0', 'Myeloid DC': '13.3', 'NK-cell': '20.2', 'Total PBMC': '12.0', 'Vd2 gdTCR': '16.5', 'Memory CD4 T-cell TFH': '14.8', 'Memory CD4 T-cell Th2': '14.7', 'Memory CD4 T-cell Th17': '13.9', 'Memory CD4 T-cell Th1\\/Th17': '16.6', 'Non-Vd2 gdTCR': '21.3', 'Memory CD4 T-cell Th1': '16.2', 'Terminal effector memory CD4 T-cell': '35.7', 'Central memory CD8 T-cell': '20.1', 'Effector memory CD8 T-cell': '17.3', 'Terminal effector memory CD8 T-cell': '26.1', 'Switched memory B-cell': '11.0', 'Plasmablast': '4.4', 'Non-switched memory B-cell': '12.3', 'Exhausted memory B-cell': '13.7', 'Progenitor cell': '27.6', 'Naive CD4 T-cell activated': '3.5', 'Naive CD8 T-cell activated': '6.9', 'Memory T-reg': '12.0', 'Naive T-reg': '19.3'}
null
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0.69, 0.27, 0.44, 0.41, 0.04, 0.03, 0.02, 0.23, 0.03, 0.0, 0.43, 0.05, 0.0, 0.0, 0.33, 0.22, 0.16, 0.59, 0.27, 0.14, 0.0, 0.04, 0.33, 0.01, 0.0, 0.48, 0.13, 0.01, 0.22, 0.03, 0.36, 0.2, 0.37, 0.79, 0.73, 0.12, 0.27, 0.61, 0.38, 0.0, 0.59, 0.73, 0.09, 0.57, 0.39, 0.05, 0.72, 0.76, 0.06, 0.4, 0.0, 0.34, 0.62, 0.12, 0.4, 0.67, 0.51, 0.36, 0.76, 0.93, 0.96]
null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
92.848567
0.265863
611
O60260
Q9Y4K3
31558697
UbiNet, UbiBrowser
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
TRAF6
MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
Homo sapiens
Cytoplasm, Cytoplasm, cell cortex, Nucleus, Lipid droplet
Low tissue specificity
{'Ciliated cells': '6.4', 'Basal respiratory cells': '6.8', 'Club cells': '5.5', 'Ionocytes': '5.5', 'Mucus glandular cells': '11.3', 'Serous glandular cells': '3.8', 'Gastric mucus-secreting cells': '5.9', 'Proximal enterocytes': '10.4', 'Paneth cells': '10.8', 'Distal enterocytes': '8.8', 'Intestinal goblet cells': '7.1', 'Exocrine glandular cells': '-0.576', 'Basal prostatic cells': '7.5', 'Prostatic glandular cells': '6.3', 'Breast glandular cells': '0.445', 'Breast myoepithelial cells': '0.568', 'Glandular and luminal cells': '10.9', 'Secretory cells': '11.2', 'Basal keratinocytes': '10.3', 'Suprabasal keratinocytes': '10.4', 'Basal squamous epithelial cells': '6.4', 'Squamous epithelial cells': '9.5', 'Alveolar cells type 1': '0.203', 'Alveolar cells type 2': '-0.506', 'Salivary duct cells': '9.2', 'Ductal cells': '0.661', 'Hepatocytes': '0.350', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '0.239', 'Distal tubular cells': '6.1', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.382', 'Sertoli cells': '0.613', 'Granulosa cells': '8.0', 'Enteroendocrine cells': '9.1', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.475', 'Excitatory neurons': '28.0', 'Inhibitory neurons': '23.0', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '3.8', 'Bipolar cells': '6.0', 'Horizontal cells': '5.7', 'Astrocytes': '12.4', 'Oligodendrocyte precursor cells': '10.4', 'Oligodendrocytes': '27.1', 'Microglial cells': '17.0', 'Muller glia cells': '5.3', 'Schwann cells': '0.103', 'Spermatogonia': '0.568', 'Spermatocytes': '0.352', 'Early spermatids': '-0.180', 'Late spermatids': '-0.584', 'Oocytes': '15.4', 'Cytotrophoblasts': '7.0', 'Syncytiotrophoblasts': '8.0', 'Extravillous trophoblasts': '6.8', 'Endothelial cells': '14.2', 'Lymphatic endothelial cells': '7.0', 'Cardiomyocytes': '0.541', 'Skeletal myocytes': '-0.347', 'Smooth muscle cells': '9.5', 'Adipocytes': '10.0', 'Melanocytes': '0.183', 'Fibroblasts': '10.0', 'Peritubular cells': '0.503', 'Endometrial stromal cells': '7.0', 'Ovarian stromal cells': '6.9', 'Undifferentiated cells': '5.3', 'T-cells': '11.8', 'B-cells': '13.4', 'Plasma cells': '9.4', 'Nk-cells': '11.3', 'Granulocytes': '11.4', 'Monocytes': '13.9', 'Macrophages': '10.3', 'Hofbauer cells': '7.1', 'Kupffer cells': '8.3', 'Dendritic cells': '14.9', 'Langerhans cells': '0.146', 'Erythroid cells': '0.147', 'Adipocytes (Subcutaneous)': '-0.302', 'Adipocytes (Visceral)': '-0.406', 'Breast glandular cells (progenitors)': '0.305', 'Adipocytes (Breast)': '-0.577', 'Colon enterocytes': '-0.139', 'Colon enteroendocrine cells': '0.257', 'Enteric glia cells': '0.217', 'Mitotic cells (Colon)': '-0.030', 'Mitotic cells (Heart)': '0.497', 'Podocytes': '-0.011', 'Ascending Loop of Henle cells': '0.339', 'Intercalated cells': '-0.002', 'Cholangiocyte': '0.347', 'NK-cells (Liver)': '-0.103', 'Respiratory ciliated cells': '0.122', 'Mitotic cells (Lung)': '-0.196', 'NK-cells (Lung)': '0.500', 'B-cells (Lung)': '0.277', 'Alpha cells': '0.409', 'Beta cells': '0.273', 'Prostate glandular cells': '-0.375', 'Prostate basal glandular cells': '0.074', 'Urothelial cells': '0.226', 'Keratinocyte (other)': '0.355', 'Keratinocyte (granular)': '-0.010', 'Hair cortex cells': '-0.236', 'Inner root sheath cells': '-0.099', 'Outer root sheath cells': '-0.029', 'Sebaceous gland cells': '-0.094', 'Eccrine sweat gland cells': '-0.078', 'Adipocytes (Skin)': '-0.234', 'Mitotic cells (Skin)': '0.239', 'Parietal cells': '-0.555', 'Chief cells': '-0.555', 'Gastric mucous cells': '-0.311', 'Gastric enteroendocrine cells': '-0.367', 'Mitotic cells (Stomach)': '0.006', 'Parafollicular cells': '0.019', 'Thyroid glandular cells': '0.187', 'Mitotic cells (Thyroid)': '0.016', 'Adrenal cortex cells': '0.446', 'Adrenal medulla cells': '-0.039', 'Mitotic cells (Adrenal gland)': '0.319', 'Minor salivary glandular cells': '0.547', 'Minor salivary gland ductal cells': '0.222', 'Minor salivary gland basal cells': '0.378', 'Mitotic cells (Minor salivary gland)': '0.451', 'Adipocytes (Minor salivary gland)': '0.237', 'Somatotropes': '-0.077', 'Lactotropes': '-0.152', 'Gonadotropes': '0.084', 'Corticotropes': '-0.155', 'Thyrotropes': '0.072', 'Undifferentiated cells (Pituitary gland)': '0.177', 'Mitotic cells (Spleen)': '-0.147', 'Platelets': '-0.236', 'Erythrocytes': '-0.054', 'Hematopoietic stem cells': '-0.292', 'B-cells (Spleen)': '0.241', 'NK-cells (Spleen)': '0.337', 'Amygdala excitatory': '39.9', 'Cerebellar inhibitory': '21.9', 'Cge interneuron': '26.6', 'Deep-layer corticothalamic and 6b': '36.9', 'Deep-layer intratelencephalic': '41.9', 'Deep-layer near-projecting': '37.5', 'Eccentric medium spiny neuron': '29.9', 'Hippocampal ca1-3': '42.5', 'Hippocampal ca4': '24.3', 'Hippocampal dentate gyrus': '33.6', 'Lamp5-lhx6 and chandelier': '26.6', 'Lower rhombic lip': '36.6', 'Mammillary body': '34.8', 'Medium spiny neuron': '35.1', 'Mge interneuron': '33.9', 'Midbrain-derived inhibitory': '28.8', 'Miscellaneous': '38.8', 'Splatter': '30.9', 'Thalamic excitatory': '42.6', 'Upper rhombic lip': '22.8', 'Upper-layer intratelencephalic': '38.0', 'Astrocyte': '27.1', 'Bergmann glia': '20.3', 'Central nervous system macrophage': '40.4', 'Choroid plexus epithelial cell': '33.2', 'Committed oligodendrocyte precursor': '27.5', 'Ependymal cell': '17.7', 'Oligodendrocyte': '42.0', 'Oligodendrocyte precursor cell': '21.3', 'Endothelial cell': '56.3', 'Pericyte': '36.3', 'Vascular associated smooth muscle cell': '39.5', 'Fibroblast': '26.5', 'Leukocyte': '34.8', 'Basophil': '67.3', 'Eosinophil': '34.7', 'Neutrophil': '48.8', 'Classical monocyte': '32.2', 'Non-classical monocyte': '46.0', 'Intermediate monocyte': '29.5', 'T-reg': '31.7', 'GdT-cell': '17.9', 'MAIT T-cell': '40.4', 'Memory CD4 T-cell': '15.1', 'Naive CD4 T-cell': '39.2', 'Memory CD8 T-cell': '17.5', 'Naive CD8 T-cell': '33.4', 'Memory B-cell': '17.1', 'Naive B-cell': '59.7', 'Plasmacytoid DC': '33.9', 'Myeloid DC': '24.3', 'NK-cell': '61.5', 'Total PBMC': '32.7', 'Vd2 gdTCR': '44.7', 'Memory CD4 T-cell Th1\\/Th17': '50.1', 'Memory CD4 T-cell Th17': '46.9', 'Memory CD4 T-cell Th2': '49.6', 'Non-Vd2 gdTCR': '42.7', 'Memory CD4 T-cell Th1': '43.2', 'Memory CD4 T-cell TFH': '38.6', 'Terminal effector memory CD4 T-cell': '38.2', 'Central memory CD8 T-cell': '34.8', 'Effector memory CD8 T-cell': '52.5', 'Terminal effector memory CD8 T-cell': '48.3', 'Non-switched memory B-cell': '25.2', 'Plasmablast': '30.7', 'Switched memory B-cell': '25.4', 'Exhausted memory B-cell': '24.1', 'Progenitor cell': '22.3', 'Memory T-reg': '36.7', 'Naive CD4 T-cell activated': '27.7', 'Naive CD8 T-cell activated': '25.5', 'Naive T-reg': '39.3'}
1LB4, 1LB5, 1LB6, 2ECI, 2JMD, 3HCS, 3HCT, 3HCU, 4Z8M, 5ZUJ, 6A33, 7L3L, 8HZ2
{'Adipose Tissue': 9.363179401993357, 'Adrenal Gland': 6.2882984496124035, 'Bladder': 9.04309523809524, 'Blood': 4.581179332615716, 'Blood Vessel': 12.141896629213484, 'Brain': 3.6537502271006814, 'Breast': 8.987206971677558, 'Cervix Uteri': 11.423473684210526, 'Colon': 7.732209242618741, 'Esophagus': 7.91996124567474, 'Fallopian Tube': 11.163666666666666, 'Heart': 4.6233783972125435, 'Kidney': 4.875640449438203, 'Liver': 3.2195849557522127, 'Lung': 13.951828719723183, 'Muscle': 4.899508094645081, 'Nerve': 11.194544426494346, 'Ovary': 11.8934, 'Pancreas': 3.0836737804878047, 'Pituitary': 6.5534946996466426, 'Prostate': 7.792232653061224, 'Salivary Gland': 7.184561728395061, 'Skin': 9.094258153676064, 'Small Intestine': 8.007561497326202, 'Spleen': 9.109311203319502, 'Stomach': 5.8756295264623954, 'Testis': 10.41815512465374, 'Thyroid': 11.371986217457886, 'Uterus': 13.088964788732394, 'Vagina': 10.93697435897436}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
85.06523
0.467069
1,478
O60260
Q9Y5U9
23503661
DegPred
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
IER3IP1
MAFTLYSLLQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLMNLIRSVRTVMRVPLIIVNSIAIVLLLLFG
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '48.1', 'Basal respiratory cells': '158.3', 'Club cells': '70.4', 'Ionocytes': '99.8', 'Mucus glandular cells': '19.8', 'Serous glandular cells': '28.8', 'Gastric mucus-secreting cells': '50.7', 'Proximal enterocytes': '122.1', 'Paneth cells': '62.5', 'Distal enterocytes': '67.5', 'Intestinal goblet cells': '104.9', 'Exocrine glandular cells': '-0.562', 'Basal prostatic cells': '31.2', 'Prostatic glandular cells': '36.0', 'Breast glandular cells': '0.122', 'Breast myoepithelial cells': '0.044', 'Glandular and luminal cells': '63.0', 'Secretory cells': '62.4', 'Basal keratinocytes': '74.7', 'Suprabasal keratinocytes': '91.7', 'Basal squamous epithelial cells': '62.5', 'Squamous epithelial cells': '64.2', 'Alveolar cells type 1': '0.128', 'Alveolar cells type 2': '0.114', 'Salivary duct cells': '18.1', 'Ductal cells': '0.531', 'Hepatocytes': '0.312', 'Cholangiocytes': '87.8', 'Proximal tubular cells': '0.263', 'Distal tubular cells': '110.6', 'Collecting duct cells': '46.7', 'Mesothelial cells': '0.220', 'Sertoli cells': '0.505', 'Granulosa cells': '55.7', 'Enteroendocrine cells': '73.1', 'Pancreatic endocrine cells': '173.2', 'Leydig cells': '0.554', 'Excitatory neurons': '15.2', 'Inhibitory neurons': '16.7', 'Cone photoreceptor cells': '79.9', 'Rod photoreceptor cells': '42.7', 'Bipolar cells': '45.2', 'Horizontal cells': '27.7', 'Astrocytes': '7.4', 'Oligodendrocyte precursor cells': '15.1', 'Oligodendrocytes': '17.8', 'Microglial cells': '11.6', 'Muller glia cells': '68.6', 'Schwann cells': '0.143', 'Spermatogonia': '0.572', 'Spermatocytes': '0.347', 'Early spermatids': '-0.237', 'Late spermatids': '-0.585', 'Oocytes': '160.3', 'Cytotrophoblasts': '104.2', 'Syncytiotrophoblasts': '193.8', 'Extravillous trophoblasts': '128.2', 'Endothelial cells': '64.5', 'Lymphatic endothelial cells': '56.0', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '0.159', 'Smooth muscle cells': '54.1', 'Adipocytes': '77.7', 'Melanocytes': '0.097', 'Fibroblasts': '77.3', 'Peritubular cells': '0.485', 'Endometrial stromal cells': '48.1', 'Ovarian stromal cells': '69.5', 'Undifferentiated cells': '98.7', 'T-cells': '50.8', 'B-cells': '39.7', 'Plasma cells': '115.3', 'Nk-cells': '59.7', 'Granulocytes': '38.4', 'Monocytes': '33.4', 'Macrophages': '47.3', 'Hofbauer cells': '95.5', 'Kupffer cells': '50.8', 'Dendritic cells': '54.7', 'Langerhans cells': '0.289', 'Erythroid cells': '-0.036', 'Adipocytes (Subcutaneous)': '-0.017', 'Adipocytes (Visceral)': '-0.231', 'Breast glandular cells (progenitors)': '-0.092', 'Adipocytes (Breast)': '0.004', 'Colon enterocytes': '-0.034', 'Colon enteroendocrine cells': '0.353', 'Enteric glia cells': '0.223', 'Mitotic cells (Colon)': '0.110', 'Mitotic cells (Heart)': '0.504', 'Podocytes': '0.219', 'Ascending Loop of Henle cells': '0.320', 'Intercalated cells': '0.148', 'Cholangiocyte': '0.271', 'NK-cells (Liver)': '-0.250', 'Respiratory ciliated cells': '-0.052', 'Mitotic cells (Lung)': '0.141', 'NK-cells (Lung)': '-0.083', 'B-cells (Lung)': '-0.234', 'Alpha cells': '0.379', 'Beta cells': '0.247', 'Prostate glandular cells': '0.250', 'Prostate basal glandular cells': '0.187', 'Urothelial cells': '0.162', 'Keratinocyte (other)': '0.198', 'Keratinocyte (granular)': '-0.039', 'Hair cortex cells': '-0.055', 'Inner root sheath cells': '0.055', 'Outer root sheath cells': '0.143', 'Sebaceous gland cells': '0.130', 'Eccrine sweat gland cells': '-0.036', 'Adipocytes (Skin)': '-0.138', 'Mitotic cells (Skin)': '0.233', 'Parietal cells': '-0.212', 'Chief cells': '0.016', 'Gastric mucous cells': '0.058', 'Gastric enteroendocrine cells': '0.086', 'Mitotic cells (Stomach)': '0.298', 'Parafollicular cells': '0.162', 'Thyroid glandular cells': '0.531', 'Mitotic cells (Thyroid)': '-0.042', 'Adrenal cortex cells': '0.457', 'Adrenal medulla cells': '0.123', 'Mitotic cells (Adrenal gland)': '0.122', 'Minor salivary glandular cells': '0.144', 'Minor salivary gland ductal cells': '0.116', 'Minor salivary gland basal cells': '0.112', 'Mitotic cells (Minor salivary gland)': '0.029', 'Adipocytes (Minor salivary gland)': '-0.149', 'Somatotropes': '0.279', 'Lactotropes': '0.403', 'Gonadotropes': '0.175', 'Corticotropes': '0.170', 'Thyrotropes': '0.386', 'Undifferentiated cells (Pituitary gland)': '-0.198', 'Mitotic cells (Spleen)': '-0.053', 'Platelets': '-0.220', 'Erythrocytes': '-0.097', 'Hematopoietic stem cells': '-0.195', 'B-cells (Spleen)': '0.064', 'NK-cells (Spleen)': '0.144', 'Amygdala excitatory': '0.3', 'Cerebellar inhibitory': '1.5', 'Cge interneuron': '1.1', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.4', 'Deep-layer near-projecting': '0.6', 'Eccentric medium spiny neuron': '0.3', 'Hippocampal ca1-3': '0.3', 'Hippocampal ca4': '0.2', 'Hippocampal dentate gyrus': '0.4', 'Lamp5-lhx6 and chandelier': '0.9', 'Lower rhombic lip': '1.1', 'Mammillary body': '0.7', 'Medium spiny neuron': '0.2', 'Mge interneuron': '0.6', 'Midbrain-derived inhibitory': '0.9', 'Miscellaneous': '0.8', 'Splatter': '0.9', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '1.8', 'Upper-layer intratelencephalic': '0.6', 'Astrocyte': '0.4', 'Bergmann glia': '0.9', 'Central nervous system macrophage': '0.7', 'Choroid plexus epithelial cell': '1.2', 'Committed oligodendrocyte precursor': '1.0', 'Ependymal cell': '0.8', 'Oligodendrocyte': '1.1', 'Oligodendrocyte precursor cell': '1.0', 'Endothelial cell': '0.9', 'Pericyte': '2.0', 'Vascular associated smooth muscle cell': '1.6', 'Fibroblast': '0.8', 'Leukocyte': '1.0', 'Basophil': '22.9', 'Eosinophil': '16.1', 'Neutrophil': '6.5', 'Classical monocyte': '11.8', 'Non-classical monocyte': '16.6', 'Intermediate monocyte': '36.5', 'T-reg': '34.7', 'GdT-cell': '25.1', 'MAIT T-cell': '52.9', 'Memory CD4 T-cell': '21.1', 'Naive CD4 T-cell': '11.8', 'Memory CD8 T-cell': '21.5', 'Naive CD8 T-cell': '11.2', 'Memory B-cell': '18.7', 'Naive B-cell': '9.9', 'Plasmacytoid DC': '85.1', 'Myeloid DC': '36.8', 'NK-cell': '15.0', 'Total PBMC': '41.3', 'Vd2 gdTCR': '51.7', 'Memory CD4 T-cell TFH': '9.1', 'Memory CD4 T-cell Th2': '13.8', 'Memory CD4 T-cell Th17': '11.9', 'Memory CD4 T-cell Th1\\/Th17': '19.3', 'Non-Vd2 gdTCR': '52.7', 'Memory CD4 T-cell Th1': '11.5', 'Terminal effector memory CD4 T-cell': '51.5', 'Central memory CD8 T-cell': '35.2', 'Effector memory CD8 T-cell': '55.5', 'Terminal effector memory CD8 T-cell': '50.6', 'Switched memory B-cell': '40.0', 'Plasmablast': '66.7', 'Non-switched memory B-cell': '30.8', 'Exhausted memory B-cell': '33.7', 'Progenitor cell': '33.1', 'Naive CD4 T-cell activated': '25.7', 'Naive CD8 T-cell activated': '16.2', 'Memory T-reg': '7.7', 'Naive T-reg': '13.8'}
null
{'Adipose Tissue': 19.380091362126247, 'Adrenal Gland': 16.497879844961243, 'Bladder': 17.739047619047618, 'Blood': 6.8684624327233585, 'Blood Vessel': 19.19925243445693, 'Brain': 10.19438304314913, 'Breast': 19.080311546840957, 'Cervix Uteri': 20.426315789473687, 'Colon': 14.556935815147623, 'Esophagus': 13.984318339100346, 'Fallopian Tube': 18.553333333333335, 'Heart': 9.543268408826943, 'Kidney': 17.79685393258427, 'Liver': 11.868853982300884, 'Lung': 22.82863321799308, 'Muscle': 16.085432129514324, 'Nerve': 17.988534733441035, 'Ovary': 19.522222222222226, 'Pancreas': 7.848990853658536, 'Pituitary': 26.922526501766782, 'Prostate': 17.77247755102041, 'Salivary Gland': 18.628987654320987, 'Skin': 23.686865118850193, 'Small Intestine': 14.10073796791444, 'Spleen': 15.011651452282155, 'Stomach': 13.451885793871869, 'Testis': 15.472864265927978, 'Thyroid': 20.69097702909648, 'Uterus': 19.78880281690141, 'Vagina': 19.505064102564106}
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[55.39, 64.27, 66.78, 75.46, 76.67, 78.03, 76.31, 75.6, 74.8, 69.2, 72.61, 75.08, 68.69, 69.18, 69.64, 68.8, 67.84, 61.95, 61.87, 61.13, 60.82, 60.84, 56.83, 57.08, 54.78, 52.47, 53.04, 50.07, 50.97, 58.32, 57.43, 51.52, 46.86, 47.35, 48.14, 46.28, 50.35, 50.09, 47.13, 47.47, 45.53, 47.45, 52.31, 49.67, 53.54, 55.52, 65.79, 68.69, 65.25, 71.04, 73.52, 77.59, 73.6, 75.15, 75.55, 72.3, 71.44, 71.64, 69.93, 62.33, 64.76, 65.47, 60.73, 62.6, 63.45, 60.03, 57.52, 61.98, 66.86, 63.78, 67.1, 67.34, 72.73, 63.2, 63.91, 68.42, 66.38, 57.4, 64.37, 67.42, 66.81, 55.08]
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
62.71122
0.617073
3,009
O60260
Q9Y6H5
11590439, PRKN2_HUMAN, BioGrid E3NethUbiquitome
UbiNet, UbiBrowser, 31181401
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
SNCAIP
MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDTQNEDRSVSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPQELGPGDGVGGPPGKSSEPSTSLGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLSGKACSTGSSESSSSNMAPFCVLSPVKSPHLRKASAVIHDQHKLSTEETEISPPLVKCGSAYEPENQSKDFLNKTFSDPHGRKVEKTTPDCQLRAFHLQSSAAESKPEEQVSGLNRTSSQGPEERSEYLKKVKSILNIVKEGQISLLPHLAADNLDKIHDENGNNLLHIAASQGHAECLQHLTSLMGEDCLNERNTEKLTPAGLAIKNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCYGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERQGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQFLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSASSRARPKAKDEDSDKILRQLLGKEISENVCTQEKLSLEFQDAQASSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRPRPQPIVESVESMDSAESLHLMIKKHTLASGGRRFPFSIKASKSLDGHSPSPTSESSEPDLESQYPGSGSIPPNQPSGDPQQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRVTFEEPVVQMEQPSLELNGEKDKDKGRTLQRTSTSNESGDQLKRPFGAFRSIMETLSGNQNNNNNYQAANQLKTSTLPLTSLGRKTDAKGNPASSASKGKNKAA
Homo sapiens
Cytoplasm
Tissue enhanced (cervix, endometrium, ovary)
{'Ciliated cells': '7.6', 'Basal respiratory cells': '0.8', 'Club cells': '1.3', 'Ionocytes': '0.7', 'Mucus glandular cells': '0.3', 'Serous glandular cells': '6.8', 'Gastric mucus-secreting cells': '0.6', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.7', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.325', 'Basal prostatic cells': '0.5', 'Prostatic glandular cells': '0.1', 'Breast glandular cells': '0.362', 'Breast myoepithelial cells': '0.452', 'Glandular and luminal cells': '1.3', 'Secretory cells': '0.4', 'Basal keratinocytes': '3.8', 'Suprabasal keratinocytes': '3.1', 'Basal squamous epithelial cells': '2.0', 'Squamous epithelial cells': '1.6', 'Alveolar cells type 1': '-0.018', 'Alveolar cells type 2': '-0.027', 'Salivary duct cells': '0.5', 'Ductal cells': '0.400', 'Hepatocytes': '0.173', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '-0.113', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.736', 'Sertoli cells': '-0.554', 'Granulosa cells': '0.8', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '-0.537', 'Excitatory neurons': '21.1', 'Inhibitory neurons': '60.1', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '1.3', 'Astrocytes': '80.2', 'Oligodendrocyte precursor cells': '28.8', 'Oligodendrocytes': '1.8', 'Microglial cells': '12.5', 'Muller glia cells': '0.7', 'Schwann cells': '0.073', 'Spermatogonia': '-0.270', 'Spermatocytes': '0.088', 'Early spermatids': '0.752', 'Late spermatids': '0.660', 'Oocytes': '9.6', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.1', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '11.5', 'Lymphatic endothelial cells': '33.3', 'Cardiomyocytes': '-0.103', 'Skeletal myocytes': '0.288', 'Smooth muscle cells': '4.3', 'Adipocytes': '7.2', 'Melanocytes': '0.174', 'Fibroblasts': '4.0', 'Peritubular cells': '-0.307', 'Endometrial stromal cells': '55.4', 'Ovarian stromal cells': '17.0', 'Undifferentiated cells': '0.0', 'T-cells': '0.2', 'B-cells': '0.0', 'Plasma cells': '0.1', 'Nk-cells': '0.0', 'Granulocytes': '1.6', 'Monocytes': '0.0', 'Macrophages': '0.6', 'Hofbauer cells': '0.2', 'Kupffer cells': '0.4', 'Dendritic cells': '0.0', 'Langerhans cells': '0.011', 'Erythroid cells': '-0.070', 'Adipocytes (Subcutaneous)': '-0.497', 'Adipocytes (Visceral)': '-0.407', 'Breast glandular cells (progenitors)': '0.109', 'Adipocytes (Breast)': '-0.339', 'Colon enterocytes': '-0.112', 'Colon enteroendocrine cells': '0.339', 'Enteric glia cells': '0.513', 'Mitotic cells (Colon)': '-0.033', 'Mitotic cells (Heart)': '0.253', 'Podocytes': '-0.194', 'Ascending Loop of Henle cells': '0.494', 'Intercalated cells': '-0.030', 'Cholangiocyte': '0.152', 'NK-cells (Liver)': '-0.007', 'Respiratory ciliated cells': '0.466', 'Mitotic cells (Lung)': '0.061', 'NK-cells (Lung)': '-0.006', 'B-cells (Lung)': '0.107', 'Alpha cells': '0.225', 'Beta cells': '0.038', 'Prostate glandular cells': '-0.078', 'Prostate basal glandular cells': '0.392', 'Urothelial cells': '0.343', 'Keratinocyte (other)': '-0.385', 'Keratinocyte (granular)': '-0.470', 'Hair cortex cells': '0.545', 'Inner root sheath cells': '0.682', 'Outer root sheath cells': '0.679', 'Sebaceous gland cells': '0.133', 'Eccrine sweat gland cells': '0.383', 'Adipocytes (Skin)': '0.288', 'Mitotic cells (Skin)': '0.305', 'Parietal cells': '-0.641', 'Chief cells': '-0.621', 'Gastric mucous cells': '-0.368', 'Gastric enteroendocrine cells': '-0.403', 'Mitotic cells (Stomach)': '0.026', 'Parafollicular cells': '0.054', 'Thyroid glandular cells': '0.115', 'Mitotic cells (Thyroid)': '0.257', 'Adrenal cortex cells': '0.202', 'Adrenal medulla cells': '-0.097', 'Mitotic cells (Adrenal gland)': '-0.048', 'Minor salivary glandular cells': '-0.075', 'Minor salivary gland ductal cells': '-0.178', 'Minor salivary gland basal cells': '0.444', 'Mitotic cells (Minor salivary gland)': '0.509', 'Adipocytes (Minor salivary gland)': '0.205', 'Somatotropes': '0.145', 'Lactotropes': '0.278', 'Gonadotropes': '0.136', 'Corticotropes': '0.091', 'Thyrotropes': '0.247', 'Undifferentiated cells (Pituitary gland)': '0.010', 'Mitotic cells (Spleen)': '-0.258', 'Platelets': '-0.130', 'Erythrocytes': '-0.112', 'Hematopoietic stem cells': '-0.282', 'B-cells (Spleen)': '0.129', 'NK-cells (Spleen)': '0.314', 'Amygdala excitatory': '48.0', 'Cerebellar inhibitory': '44.0', 'Cge interneuron': '97.1', 'Deep-layer corticothalamic and 6b': '6.2', 'Deep-layer intratelencephalic': '21.1', 'Deep-layer near-projecting': '30.0', 'Eccentric medium spiny neuron': '69.1', 'Hippocampal ca1-3': '11.8', 'Hippocampal ca4': '25.2', 'Hippocampal dentate gyrus': '117.0', 'Lamp5-lhx6 and chandelier': '34.2', 'Lower rhombic lip': '70.4', 'Mammillary body': '2.4', 'Medium spiny neuron': '174.7', 'Mge interneuron': '39.1', 'Midbrain-derived inhibitory': '1.7', 'Miscellaneous': '69.1', 'Splatter': '62.7', 'Thalamic excitatory': '113.5', 'Upper rhombic lip': '141.6', 'Upper-layer intratelencephalic': '30.6', 'Astrocyte': '135.0', 'Bergmann glia': '193.6', 'Central nervous system macrophage': '7.1', 'Choroid plexus epithelial cell': '256.3', 'Committed oligodendrocyte precursor': '33.6', 'Ependymal cell': '493.6', 'Oligodendrocyte': '2.3', 'Oligodendrocyte precursor cell': '65.3', 'Endothelial cell': '32.2', 'Pericyte': '3.6', 'Vascular associated smooth muscle cell': '54.9', 'Fibroblast': '47.7', 'Leukocyte': '1.3', 'Basophil': '13.5', 'Eosinophil': '0.0', 'Neutrophil': '4.1', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '2.3', 'T-reg': '2.5', 'GdT-cell': '0.1', 'MAIT T-cell': '2.5', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '4.1', 'Myeloid DC': '2.4', 'NK-cell': '0.0', 'Total PBMC': '1.3', 'Vd2 gdTCR': '1.6', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '2.5', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '3.4', 'Central memory CD8 T-cell': '2.2', 'Effector memory CD8 T-cell': '2.0', 'Terminal effector memory CD8 T-cell': '2.4', 'Non-switched memory B-cell': '3.1', 'Plasmablast': '2.3', 'Switched memory B-cell': '3.3', 'Exhausted memory B-cell': '4.1', 'Progenitor cell': '2.5', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
2KES
{'Adipose Tissue': 5.344149418604651, 'Adrenal Gland': 0.905022480620155, 'Bladder': 1.267552380952381, 'Blood': 0.04724018729817, 'Blood Vessel': 6.352508539325843, 'Brain': 3.577011945495837, 'Breast': 2.9110298474945537, 'Cervix Uteri': 26.247105263157895, 'Colon': 1.8073888318356868, 'Esophagus': 1.0860244775086505, 'Fallopian Tube': 4.528111111111111, 'Heart': 0.6268391869918699, 'Kidney': 1.2312552808988764, 'Liver': 0.2608563274336283, 'Lung': 1.6442996539792387, 'Muscle': 0.263904396014944, 'Nerve': 3.2478862681744753, 'Ovary': 25.75625555555556, 'Pancreas': 0.0820531158536585, 'Pituitary': 2.6382381625441695, 'Prostate': 5.662102448979591, 'Salivary Gland': 0.6982803086419753, 'Skin': 1.514619701492537, 'Small Intestine': 1.890746524064171, 'Spleen': 8.236390041493776, 'Stomach': 1.1189440111420612, 'Testis': 7.81190027700831, 'Thyroid': 1.796037442572741, 'Uterus': 23.114978873239433, 'Vagina': 5.683616025641025}
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null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
52.189804
0.761839
615
O60260
Q9Y6K9
19880420
UbiNet, UbiBrowser, 31181401
PRKN
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQSIVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKDSPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGECQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEAYHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV
Homo sapiens
Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion, Mitochondrion outer membrane, Cell projection, neuron projection, Postsynaptic density, Presynapse
Tissue enhanced (skeletal muscle, tongue)
{'Ciliated cells': '2.5', 'Basal respiratory cells': '0.9', 'Club cells': '2.4', 'Ionocytes': '1.5', 'Mucus glandular cells': '4.0', 'Serous glandular cells': '1.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '2.6', 'Paneth cells': '2.1', 'Distal enterocytes': '1.6', 'Intestinal goblet cells': '1.9', 'Exocrine glandular cells': '-0.364', 'Basal prostatic cells': '1.6', 'Prostatic glandular cells': '2.4', 'Breast glandular cells': '0.072', 'Breast myoepithelial cells': '0.137', 'Glandular and luminal cells': '3.8', 'Secretory cells': '2.5', 'Basal keratinocytes': '2.0', 'Suprabasal keratinocytes': '1.9', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '2.4', 'Alveolar cells type 1': '0.289', 'Alveolar cells type 2': '-0.232', 'Salivary duct cells': '2.1', 'Ductal cells': '0.329', 'Hepatocytes': '0.473', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '21.5', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.203', 'Sertoli cells': '0.161', 'Granulosa cells': '5.1', 'Enteroendocrine cells': '4.4', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.010', 'Excitatory neurons': '312.1', 'Inhibitory neurons': '392.1', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '10.0', 'Bipolar cells': '6.6', 'Horizontal cells': '12.6', 'Astrocytes': '362.6', 'Oligodendrocyte precursor cells': '445.2', 'Oligodendrocytes': '350.5', 'Microglial cells': '221.9', 'Muller glia cells': '4.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.263', 'Spermatocytes': '0.323', 'Early spermatids': '0.334', 'Late spermatids': '0.064', 'Oocytes': '9.6', 'Cytotrophoblasts': '1.0', 'Syncytiotrophoblasts': '0.7', 'Extravillous trophoblasts': '0.3', 'Endothelial cells': '3.0', 'Lymphatic endothelial cells': '4.6', 'Cardiomyocytes': '0.801', 'Skeletal myocytes': '0.363', 'Smooth muscle cells': '3.6', 'Adipocytes': '3.2', 'Melanocytes': '0.274', 'Fibroblasts': '4.5', 'Peritubular cells': '0.078', 'Endometrial stromal cells': '2.2', 'Ovarian stromal cells': '6.8', 'Undifferentiated cells': '1.7', 'T-cells': '2.3', 'B-cells': '3.8', 'Plasma cells': '1.0', 'Nk-cells': '1.0', 'Granulocytes': '2.0', 'Monocytes': '0.4', 'Macrophages': '1.3', 'Hofbauer cells': '1.1', 'Kupffer cells': '1.0', 'Dendritic cells': '2.2', 'Langerhans cells': '0.078', 'Erythroid cells': '0.039', 'Adipocytes (Subcutaneous)': '0.097', 'Adipocytes (Visceral)': '0.301', 'Breast glandular cells (progenitors)': '0.044', 'Adipocytes (Breast)': '0.090', 'Colon enterocytes': '-0.247', 'Colon enteroendocrine cells': '0.177', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '-0.212', 'Mitotic cells (Heart)': '0.360', 'Podocytes': '0.061', 'Ascending Loop of Henle cells': '0.504', 'Intercalated cells': '0.265', 'Cholangiocyte': '0.156', 'NK-cells (Liver)': '0.012', 'Respiratory ciliated cells': '0.040', 'Mitotic cells (Lung)': '-0.139', 'NK-cells (Lung)': '0.248', 'B-cells (Lung)': '0.131', 'Alpha cells': '0.298', 'Beta cells': '0.182', 'Prostate glandular cells': '-0.327', 'Prostate basal glandular cells': '-0.238', 'Urothelial cells': '-0.201', 'Keratinocyte (other)': '0.030', 'Keratinocyte (granular)': '-0.220', 'Hair cortex cells': '0.391', 'Inner root sheath cells': '0.458', 'Outer root sheath cells': '0.486', 'Sebaceous gland cells': '0.047', 'Eccrine sweat gland cells': '0.201', 'Adipocytes (Skin)': '0.074', 'Mitotic cells (Skin)': '0.401', 'Parietal cells': '-0.459', 'Chief cells': '-0.514', 'Gastric mucous cells': '-0.605', 'Gastric enteroendocrine cells': '-0.522', 'Mitotic cells (Stomach)': '-0.328', 'Parafollicular cells': '0.119', 'Thyroid glandular cells': '0.448', 'Mitotic cells (Thyroid)': '0.021', 'Adrenal cortex cells': '0.795', 'Adrenal medulla cells': '0.076', 'Mitotic cells (Adrenal gland)': '0.494', 'Minor salivary glandular cells': '0.190', 'Minor salivary gland ductal cells': '0.160', 'Minor salivary gland basal cells': '-0.003', 'Mitotic cells (Minor salivary gland)': '-0.020', 'Adipocytes (Minor salivary gland)': '0.244', 'Somatotropes': '0.001', 'Lactotropes': '0.038', 'Gonadotropes': '-0.013', 'Corticotropes': '0.388', 'Thyrotropes': '0.276', 'Undifferentiated cells (Pituitary gland)': '-0.001', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '-0.215', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.228', 'B-cells (Spleen)': '0.172', 'NK-cells (Spleen)': '0.195', 'Amygdala excitatory': '726.2', 'Cerebellar inhibitory': '642.8', 'Cge interneuron': '551.4', 'Deep-layer corticothalamic and 6b': '730.6', 'Deep-layer intratelencephalic': '775.5', 'Deep-layer near-projecting': '599.2', 'Eccentric medium spiny neuron': '678.6', 'Hippocampal ca1-3': '683.9', 'Hippocampal ca4': '796.6', 'Hippocampal dentate gyrus': '705.9', 'Lamp5-lhx6 and chandelier': '699.0', 'Lower rhombic lip': '408.5', 'Mammillary body': '525.5', 'Medium spiny neuron': '895.2', 'Mge interneuron': '738.5', 'Midbrain-derived inhibitory': '688.2', 'Miscellaneous': '631.8', 'Splatter': '518.1', 'Thalamic excitatory': '491.3', 'Upper rhombic lip': '287.4', 'Upper-layer intratelencephalic': '569.5', 'Astrocyte': '879.4', 'Bergmann glia': '1229.8', 'Central nervous system macrophage': '700.5', 'Choroid plexus epithelial cell': '508.0', 'Committed oligodendrocyte precursor': '556.9', 'Ependymal cell': '381.4', 'Oligodendrocyte': '737.1', 'Oligodendrocyte precursor cell': '857.7', 'Endothelial cell': '352.5', 'Pericyte': '496.2', 'Vascular associated smooth muscle cell': '340.7', 'Fibroblast': '486.2', 'Leukocyte': '150.0', 'Basophil': '0.0', 'Eosinophil': '1.1', 'Neutrophil': '0.0', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.4', 'Intermediate monocyte': '1.0', 'T-reg': '4.3', 'GdT-cell': '0.3', 'MAIT T-cell': '0.7', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '2.6', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '2.7', 'Memory B-cell': '0.3', 'Naive B-cell': '1.6', 'Plasmacytoid DC': '0.2', 'Myeloid DC': '0.9', 'NK-cell': '0.3', 'Total PBMC': '1.4', 'Vd2 gdTCR': '1.0', 'Memory CD4 T-cell Th1\\/Th17': '1.8', 'Memory CD4 T-cell Th17': '1.5', 'Memory CD4 T-cell Th2': '1.5', 'Non-Vd2 gdTCR': '0.8', 'Memory CD4 T-cell Th1': '1.8', 'Memory CD4 T-cell TFH': '2.0', 'Terminal effector memory CD4 T-cell': '1.9', 'Central memory CD8 T-cell': '1.5', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '2.0', 'Non-switched memory B-cell': '1.3', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.6', 'Exhausted memory B-cell': '1.0', 'Progenitor cell': '2.5', 'Memory T-reg': '0.7', 'Naive CD4 T-cell activated': '0.5', 'Naive CD8 T-cell activated': '0.5', 'Naive T-reg': '3.0'}
1IYF, 2JMO, 4BM9, 4I1F, 4I1H, 5C1Z, 5C23, 5C9V, 5N2W, 5N38, 5TR5, 6GLC, 6HUE, 6N13
{}
IKBKG
MNRHLWKSQLCEMVQPSGGPAADQDVLGEESPLGKPAMLHLPSEQGAPETLQRCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLVERLGLEKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGRARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE
Homo sapiens
Cytoplasm, Nucleus
Low tissue specificity
{'Ciliated cells': '9.2', 'Basal respiratory cells': '19.1', 'Club cells': '12.2', 'Ionocytes': '20.2', 'Mucus glandular cells': '5.2', 'Serous glandular cells': '11.9', 'Gastric mucus-secreting cells': '8.8', 'Proximal enterocytes': '9.4', 'Paneth cells': '11.0', 'Distal enterocytes': '15.9', 'Intestinal goblet cells': '10.8', 'Exocrine glandular cells': '-0.619', 'Basal prostatic cells': '7.5', 'Prostatic glandular cells': '8.3', 'Breast glandular cells': '0.279', 'Breast myoepithelial cells': '0.091', 'Glandular and luminal cells': '9.3', 'Secretory cells': '9.9', 'Basal keratinocytes': '13.8', 'Suprabasal keratinocytes': '15.7', 'Basal squamous epithelial cells': '8.9', 'Squamous epithelial cells': '9.0', 'Alveolar cells type 1': '0.027', 'Alveolar cells type 2': '0.206', 'Salivary duct cells': '6.8', 'Ductal cells': '0.575', 'Hepatocytes': '0.425', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.206', 'Distal tubular cells': '0.0', 'Collecting duct cells': '13.6', 'Mesothelial cells': '-0.013', 'Sertoli cells': '0.725', 'Granulosa cells': '14.1', 'Enteroendocrine cells': '9.9', 'Pancreatic endocrine cells': '25.5', 'Leydig cells': '0.645', 'Excitatory neurons': '5.3', 'Inhibitory neurons': '4.6', 'Cone photoreceptor cells': '13.6', 'Rod photoreceptor cells': '7.9', 'Bipolar cells': '6.0', 'Horizontal cells': '9.4', 'Astrocytes': '8.1', 'Oligodendrocyte precursor cells': '2.8', 'Oligodendrocytes': '10.6', 'Microglial cells': '4.5', 'Muller glia cells': '14.3', 'Schwann cells': '0.003', 'Spermatogonia': '0.509', 'Spermatocytes': '0.088', 'Early spermatids': '-0.593', 'Late spermatids': '-0.682', 'Oocytes': '11.0', 'Cytotrophoblasts': '23.3', 'Syncytiotrophoblasts': '39.0', 'Extravillous trophoblasts': '17.3', 'Endothelial cells': '13.8', 'Lymphatic endothelial cells': '12.5', 'Cardiomyocytes': '0.569', 'Skeletal myocytes': '-0.308', 'Smooth muscle cells': '12.4', 'Adipocytes': '14.6', 'Melanocytes': '0.138', 'Fibroblasts': '13.2', 'Peritubular cells': '0.547', 'Endometrial stromal cells': '10.2', 'Ovarian stromal cells': '11.7', 'Undifferentiated cells': '8.1', 'T-cells': '19.4', 'B-cells': '19.3', 'Plasma cells': '10.6', 'Nk-cells': '35.2', 'Granulocytes': '10.1', 'Monocytes': '29.7', 'Macrophages': '19.3', 'Hofbauer cells': '29.4', 'Kupffer cells': '18.3', 'Dendritic cells': '16.5', 'Langerhans cells': '0.224', 'Erythroid cells': '-0.094', 'Adipocytes (Subcutaneous)': '0.008', 'Adipocytes (Visceral)': '0.196', 'Breast glandular cells (progenitors)': '0.072', 'Adipocytes (Breast)': '-0.058', 'Colon enterocytes': '0.055', 'Colon enteroendocrine cells': '0.092', 'Enteric glia cells': '-0.403', 'Mitotic cells (Colon)': '0.042', 'Mitotic cells (Heart)': '0.549', 'Podocytes': '-0.130', 'Ascending Loop of Henle cells': '0.397', 'Intercalated cells': '-0.029', 'Cholangiocyte': '0.299', 'NK-cells (Liver)': '-0.395', 'Respiratory ciliated cells': '-0.065', 'Mitotic cells (Lung)': '0.184', 'NK-cells (Lung)': '-0.009', 'B-cells (Lung)': '-0.091', 'Alpha cells': '0.367', 'Beta cells': '0.280', 'Prostate glandular cells': '-0.196', 'Prostate basal glandular cells': '0.284', 'Urothelial cells': '0.164', 'Keratinocyte (other)': '0.029', 'Keratinocyte (granular)': '-0.060', 'Hair cortex cells': '0.073', 'Inner root sheath cells': '0.105', 'Outer root sheath cells': '0.180', 'Sebaceous gland cells': '0.100', 'Eccrine sweat gland cells': '-0.047', 'Adipocytes (Skin)': '0.044', 'Mitotic cells (Skin)': '0.289', 'Parietal cells': '-0.452', 'Chief cells': '-0.465', 'Gastric mucous cells': '-0.092', 'Gastric enteroendocrine cells': '-0.324', 'Mitotic cells (Stomach)': '0.271', 'Parafollicular cells': '0.050', 'Thyroid glandular cells': '0.340', 'Mitotic cells (Thyroid)': '-0.024', 'Adrenal cortex cells': '0.590', 'Adrenal medulla cells': '-0.017', 'Mitotic cells (Adrenal gland)': '0.424', 'Minor salivary glandular cells': '0.417', 'Minor salivary gland ductal cells': '-0.130', 'Minor salivary gland basal cells': '0.508', 'Mitotic cells (Minor salivary gland)': '0.593', 'Adipocytes (Minor salivary gland)': '0.181', 'Somatotropes': '0.067', 'Lactotropes': '-0.086', 'Gonadotropes': '0.158', 'Corticotropes': '-0.106', 'Thyrotropes': '0.054', 'Undifferentiated cells (Pituitary gland)': '0.184', 'Mitotic cells (Spleen)': '-0.115', 'Platelets': '0.039', 'Erythrocytes': '-0.094', 'Hematopoietic stem cells': '-0.100', 'B-cells (Spleen)': '0.285', 'NK-cells (Spleen)': '0.208', 'Amygdala excitatory': '0.8', 'Cerebellar inhibitory': '1.2', 'Cge interneuron': '0.7', 'Deep-layer corticothalamic and 6b': '0.7', 'Deep-layer intratelencephalic': '1.0', 'Deep-layer near-projecting': '1.0', 'Eccentric medium spiny neuron': '0.8', 'Hippocampal ca1-3': '0.6', 'Hippocampal ca4': '0.8', 'Hippocampal dentate gyrus': '0.9', 'Lamp5-lhx6 and chandelier': '0.8', 'Lower rhombic lip': '1.7', 'Mammillary body': '1.1', 'Medium spiny neuron': '0.8', 'Mge interneuron': '0.7', 'Midbrain-derived inhibitory': '0.5', 'Miscellaneous': '1.1', 'Splatter': '0.8', 'Thalamic excitatory': '0.5', 'Upper rhombic lip': '1.4', 'Upper-layer intratelencephalic': '1.2', 'Astrocyte': '0.7', 'Bergmann glia': '1.5', 'Central nervous system macrophage': '2.3', 'Choroid plexus epithelial cell': '1.3', 'Committed oligodendrocyte precursor': '1.3', 'Ependymal cell': '0.2', 'Oligodendrocyte': '1.2', 'Oligodendrocyte precursor cell': '0.8', 'Endothelial cell': '0.9', 'Pericyte': '1.8', 'Vascular associated smooth muscle cell': '1.1', 'Fibroblast': '1.2', 'Leukocyte': '1.9', 'Basophil': '72.6', 'Eosinophil': '59.7', 'Neutrophil': '139.6', 'Classical monocyte': '15.7', 'Non-classical monocyte': '17.4', 'Intermediate monocyte': '78.8', 'T-reg': '48.8', 'GdT-cell': '34.3', 'MAIT T-cell': '56.7', 'Memory CD4 T-cell': '20.7', 'Naive CD4 T-cell': '8.8', 'Memory CD8 T-cell': '25.0', 'Naive CD8 T-cell': '12.3', 'Memory B-cell': '20.6', 'Naive B-cell': '9.1', 'Plasmacytoid DC': '61.9', 'Myeloid DC': '57.1', 'NK-cell': '28.0', 'Total PBMC': '65.1', 'Vd2 gdTCR': '68.0', 'Memory CD4 T-cell Th1\\/Th17': '11.9', 'Memory CD4 T-cell Th17': '17.6', 'Memory CD4 T-cell Th2': '17.9', 'Non-Vd2 gdTCR': '81.2', 'Memory CD4 T-cell Th1': '21.0', 'Memory CD4 T-cell TFH': '28.0', 'Terminal effector memory CD4 T-cell': '85.5', 'Central memory CD8 T-cell': '51.1', 'Effector memory CD8 T-cell': '71.5', 'Terminal effector memory CD8 T-cell': '80.8', 'Non-switched memory B-cell': '54.4', 'Plasmablast': '44.3', 'Switched memory B-cell': '63.4', 'Exhausted memory B-cell': '51.9', 'Progenitor cell': '24.4', 'Memory T-reg': '30.0', 'Naive CD4 T-cell activated': '11.1', 'Naive CD8 T-cell activated': '12.5', 'Naive T-reg': '14.8'}
2JVX, 2JVY, 3BRT, 3BRV, 3CL3, 3FX0, 4BWN, 5AAY, 5LDE, 6MI3, 6MI4, 6XX0, 6YEK, 7T2U, 7TV4
{'Adipose Tissue': 5.310117940199335, 'Adrenal Gland': 5.394152713178294, 'Bladder': 5.918285714285714, 'Blood': 7.418065877287406, 'Blood Vessel': 6.023123595505618, 'Brain': 2.5113661279333837, 'Breast': 5.223884531590413, 'Cervix Uteri': 5.464526315789473, 'Colon': 4.313581514762516, 'Esophagus': 4.906145328719723, 'Fallopian Tube': 5.8133333333333335, 'Heart': 1.910489663182346, 'Kidney': 2.5673651685393257, 'Liver': 5.209328761061947, 'Lung': 7.146034602076125, 'Muscle': 2.264095392278954, 'Nerve': 6.22426817447496, 'Ovary': 4.913522222222222, 'Pancreas': 1.5701798780487806, 'Pituitary': 3.963904593639577, 'Prostate': 4.639530612244898, 'Salivary Gland': 4.115913580246914, 'Skin': 5.78671586511885, 'Small Intestine': 5.2818395721925135, 'Spleen': 7.23036929460581, 'Stomach': 3.855528690807799, 'Testis': 4.770285318559557, 'Thyroid': 6.374505359877488, 'Uterus': 6.758746478873239, 'Vagina': 5.28924358974359}
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[41.98, 41.71, 42.35, 38.9, 37.79, 40.78, 34.81, 39.01, 36.48, 37.72, 36.84, 35.58, 42.62, 41.5, 44.42, 44.07, 36.02, 31.5, 42.5, 42.05, 38.73, 34.57, 35.75, 35.65, 28.44, 32.89, 36.09, 32.11, 32.24, 31.7, 44.91, 38.6, 34.01, 29.8, 37.74, 38.96, 35.56, 32.34, 34.51, 33.64, 36.07, 42.66, 39.72, 33.93, 35.75, 41.16, 56.77, 60.55, 65.21, 70.1, 73.74, 79.73, 79.68, 82.01, 85.51, 86.73, 85.91, 86.4, 90.1, 90.73, 91.75, 91.81, 92.7, 92.58, 91.74, 94.01, 94.83, 93.1, 94.79, 95.77, 95.7, 96.01, 96.28, 95.85, 95.47, 95.33, 96.45, 96.22, 96.26, 96.67, 96.69, 96.32, 96.33, 96.56, 96.76, 96.53, 96.93, 97.19, 97.14, 97.15, 97.43, 97.76, 97.99, 97.7, 98.01, 97.91, 97.94, 98.04, 98.03, 97.75, 97.96, 98.22, 98.23, 98.22, 97.73, 98.15, 98.13, 97.86, 98.05, 97.8, 97.87, 98.08, 97.98, 98.12, 97.84, 98.06, 97.99, 97.82, 97.8, 97.76, 97.67, 98.01, 97.82, 97.68, 97.84, 97.48, 97.78, 98.06, 97.85, 97.73, 97.51, 97.68, 97.85, 97.75, 98.13, 97.71, 97.97, 97.81, 98.19, 98.12, 98.45, 98.51, 98.58, 98.31, 98.5, 98.61, 98.36, 98.5, 98.76, 98.57, 98.51, 98.35, 98.69, 98.63, 98.42, 98.22, 98.56, 98.53, 98.54, 98.49, 98.65, 98.48, 98.26, 98.24, 98.5, 98.38, 98.13, 98.47, 98.37, 98.23, 98.17, 98.28, 98.39, 97.96, 98.49, 98.37, 98.27, 98.34, 98.53, 98.56, 98.04, 98.4, 98.26, 98.36, 98.11, 98.26, 98.22, 98.37, 98.25, 97.97, 98.18, 98.18, 97.94, 97.79, 97.97, 98.09, 98.07, 98.0, 98.54, 98.08, 98.02, 98.32, 98.29, 97.89, 97.8, 97.98, 98.07, 97.86, 98.27, 98.11, 98.02, 97.8, 98.16, 98.28, 97.85, 96.67, 97.63, 97.63, 97.02, 97.02, 97.54, 97.22, 96.62, 97.64, 97.66, 97.43, 97.31, 97.42, 97.0, 96.65, 96.8, 97.47, 95.97, 95.74, 96.33, 95.91, 94.42, 93.95, 93.32, 90.92, 87.29, 87.92, 86.07, 83.43, 76.96, 79.89, 69.03, 58.24, 50.6, 39.61, 36.74, 39.33, 34.56, 38.69, 47.2, 54.39, 55.18, 57.84, 68.08, 67.67, 75.92, 81.17, 82.15, 84.02, 88.19, 89.86, 88.76, 92.33, 92.19, 91.16, 90.64, 93.73, 94.05, 93.86, 96.05, 94.31, 94.63, 95.12, 95.5, 96.67, 94.65, 96.18, 96.77, 95.93, 95.42, 95.65, 96.11, 93.31, 95.22, 95.41, 96.26, 95.35, 93.44, 95.31, 94.2, 93.35, 95.63, 94.11, 95.01, 95.68, 96.89, 96.1, 95.17, 96.32, 95.56, 96.07, 96.12, 97.82, 97.53, 95.71, 97.47, 97.65, 97.35, 96.35, 97.71, 97.02, 97.41, 96.72, 96.91, 96.66, 97.05, 96.68, 97.11, 95.89, 96.71, 96.85, 96.77, 96.91, 97.06, 97.2, 96.32, 96.35, 96.33, 96.77, 96.37, 95.86, 96.23, 95.65, 95.32, 94.11, 94.06, 93.6, 91.87, 92.9, 90.85, 88.73, 85.81, 88.59, 84.51, 83.92, 81.76, 82.99, 81.33, 79.22, 81.64, 77.96, 77.58, 70.28, 66.43, 59.89, 55.67, 46.73, 47.43, 37.3, 36.01, 33.86, 43.17, 39.43, 54.55, 44.5, 34.79, 46.17, 39.11, 35.29, 41.56, 39.49, 37.81, 39.64, 38.33, 36.14, 38.36, 40.9, 30.38, 34.53, 31.49, 35.64, 40.03, 55.0, 49.38, 42.75, 51.75, 59.83, 60.82, 68.79, 80.25, 87.06, 86.98, 81.92, 83.21, 89.52, 85.57, 84.49, 88.33, 83.45, 85.5, 86.48, 86.96, 89.22, 88.81, 90.16, 86.81, 87.65, 90.36, 87.72, 84.71, 84.87, 86.16, 77.29, 61.04]
[0.99, 1.0, 1.0, 0.87, 0.95, 0.89, 0.91, 0.88, 0.92, 0.9, 0.89, 0.89, 0.91, 0.88, 0.87, 0.96, 0.85, 0.97, 1.0, 0.99, 1.0, 0.95, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.96, 0.99, 0.95, 1.0, 0.92, 0.96, 0.68, 0.95, 0.89, 0.95, 0.99, 0.94, 0.96, 1.0, 1.0, 0.43, 0.81, 0.71, 0.73, 0.67, 0.64, 0.57, 0.61, 0.49, 0.62, 0.51, 0.51, 0.43, 0.47, 0.64, 0.56, 0.62, 0.31, 0.44, 0.57, 0.59, 0.61, 0.56, 0.44, 0.44, 0.54, 0.57, 0.53, 0.45, 0.63, 0.48, 0.54, 0.49, 0.65, 0.61, 0.65, 0.6, 0.48, 0.37, 0.51, 0.48, 0.55, 0.64, 0.61, 0.74, 0.56, 0.58, 0.54, 0.55, 0.49, 0.44, 0.62, 0.41, 0.51, 0.46, 0.62, 0.56, 0.49, 0.67, 0.52, 0.53, 0.51, 0.37, 0.6, 0.53, 0.6, 0.61, 0.55, 0.61, 0.52, 0.73, 0.61, 0.65, 0.54, 0.52, 0.44, 0.53, 0.63, 0.52, 0.47, 0.53, 0.56, 0.64, 0.57, 0.63, 0.42, 0.7, 0.6, 0.53, 0.68, 0.53, 0.63, 0.41, 0.75, 0.55, 0.45, 0.56, 0.72, 0.56, 0.57, 0.5, 0.59, 0.48, 0.6, 0.57, 0.42, 0.53, 0.61, 0.66, 0.5, 0.53, 0.55, 0.51, 0.64, 0.64, 0.49, 0.52, 0.41, 0.44, 0.65, 0.64, 0.51, 0.6, 0.51, 0.5, 0.54, 0.46, 0.69, 0.55, 0.72, 0.57, 0.48, 0.58, 0.39, 0.58, 0.41, 0.64, 0.5, 0.57, 0.56, 0.51, 0.62, 0.64, 0.56, 0.49, 0.47, 0.61, 0.63, 0.67, 0.49, 0.48, 0.65, 0.57, 0.5, 0.51, 0.6, 0.6, 0.66, 0.65, 0.55, 0.38, 0.53, 0.6, 0.67, 0.61, 0.33, 0.53, 0.51, 0.63, 0.61, 0.68, 0.68, 0.49, 0.39, 0.52, 0.53, 0.37, 0.54, 0.74, 0.54, 0.52, 0.53, 0.41, 0.59, 0.66, 0.52, 0.52, 0.42, 0.69, 0.6, 0.51, 0.64, 0.6, 0.56, 0.64, 0.61, 0.39, 0.52, 0.61, 0.47, 0.59, 0.49, 0.51, 0.79, 0.84, 0.85, 0.93, 1.0, 0.95, 0.82, 0.91, 0.67, 0.77, 0.59, 0.57, 0.68, 0.61, 0.64, 0.61, 0.64, 0.69, 0.58, 0.57, 0.64, 0.44, 0.53, 0.59, 0.45, 0.65, 0.56, 0.46, 0.63, 0.47, 0.64, 0.57, 0.44, 0.49, 0.61, 0.57, 0.62, 0.6, 0.38, 0.49, 0.49, 0.55, 0.62, 0.48, 0.6, 0.63, 0.68, 0.59, 0.47, 0.66, 0.64, 0.64, 0.57, 0.58, 0.43, 0.43, 0.5, 0.45, 0.59, 0.6, 0.61, 0.5, 0.54, 0.6, 0.52, 0.53, 0.67, 0.56, 0.57, 0.48, 0.74, 0.51, 0.62, 0.66, 0.44, 0.65, 0.63, 0.66, 0.59, 0.52, 0.62, 0.43, 0.61, 0.51, 0.54, 0.46, 0.46, 0.61, 0.55, 0.47, 0.47, 0.67, 0.57, 0.7, 0.69, 0.52, 0.45, 0.5, 0.64, 0.51, 0.51, 0.5, 0.46, 0.63, 0.44, 0.58, 0.41, 0.49, 0.67, 0.55, 0.63, 0.72, 0.82, 0.74, 0.81, 0.87, 1.0, 1.0, 1.0, 0.98, 0.99, 0.97, 1.0, 0.8, 0.99, 0.9, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 0.96, 0.99, 0.9, 0.95, 0.94, 0.92, 0.91, 0.84, 0.61, 0.69, 0.23, 0.4, 0.03, 0.85, 0.66, 0.52, 0.78, 0.45, 0.67, 0.1, 0.78, 0.46, 0.62, 0.65, 0.33, 0.16, 0.64, 0.54, 0.24, 0.27, 0.71, 0.7, 0.19, 0.7, 0.82]
null
Part of a SCF-like complex, consisting of PRKN, CUL1 and FBXW7
SCF-LIKE
null
SNCAIP, SYT11, SEPTIN5, PSMD4, PACRG, LRRK2, RANBP2, SUMO1, AIMP2, PSMA7, RNF41, PINK1, CHPF, MFN2(phosphorylated), FBXO7, ZNF746, HSPA1L, HSPA1A, HSPA8, BAG4, BAG5, AMBRA1 , PRKN, CUL1 , FBXW7
SYT11, VDAC1, BCL2, CCNE1, GPR37, RHOT1, MFN1, MFN2, STUB1, SNCAIP, SEPTIN5, TOMM20, USP30, ZNF746, AIMP2, PARK7,HDAC6, VDAC1,
mono, 6, 11, 48, 63
null
UBE2V1, UBE2L3, UBE2L6
null
null
78.482559
0.425398
82.063341
0.632721
1,890
O60291
Q99816
17229889, BioGrid E3NethUbiquitome
UbiNet, UbiBrowser, 31181401
MGRN1
MGSILSRRIAGVEDIDIQANSAYRYPPKSGNYFASHFFMGGEKFDTPHPEGYLFGENMDLNFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSLEFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDFSEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMDGSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNGLRAVSPAIPSAPLYEEITYSGISDGLSQASCPLAAIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEEDEEKLSEDVDAPPPLGGAELALRESSSPESFITEEVDESSSPQQGTRAASIENVLQDSSPEHCGRGPPADIYLPALGPDSCSVGIDE
Homo sapiens
Early endosome, Cytoplasm, cytosol, Nucleus, Cytoplasm, cytosol, Nucleus, Cytoplasm, cytosol, Cell membrane, Cytoplasm, cytosol, Cell membrane
Low tissue specificity
{'Ciliated cells': '19.1', 'Basal respiratory cells': '12.0', 'Club cells': '16.0', 'Ionocytes': '16.2', 'Mucus glandular cells': '20.2', 'Serous glandular cells': '14.8', 'Gastric mucus-secreting cells': '43.0', 'Proximal enterocytes': '27.6', 'Paneth cells': '14.7', 'Distal enterocytes': '20.0', 'Intestinal goblet cells': '22.7', 'Exocrine glandular cells': '-0.649', 'Basal prostatic cells': '10.8', 'Prostatic glandular cells': '16.3', 'Breast glandular cells': '0.458', 'Breast myoepithelial cells': '0.333', 'Glandular and luminal cells': '22.1', 'Secretory cells': '14.9', 'Basal keratinocytes': '14.7', 'Suprabasal keratinocytes': '18.2', 'Basal squamous epithelial cells': '10.2', 'Squamous epithelial cells': '10.4', 'Alveolar cells type 1': '0.183', 'Alveolar cells type 2': '0.312', 'Salivary duct cells': '17.0', 'Ductal cells': '0.580', 'Hepatocytes': '0.051', 'Cholangiocytes': '19.1', 'Proximal tubular cells': '0.151', 'Distal tubular cells': '3.1', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.310', 'Sertoli cells': '0.631', 'Granulosa cells': '20.0', 'Enteroendocrine cells': '20.7', 'Pancreatic endocrine cells': '13.6', 'Leydig cells': '0.575', 'Excitatory neurons': '25.7', 'Inhibitory neurons': '23.9', 'Cone photoreceptor cells': '39.1', 'Rod photoreceptor cells': '36.4', 'Bipolar cells': '25.2', 'Horizontal cells': '34.6', 'Astrocytes': '22.9', 'Oligodendrocyte precursor cells': '17.5', 'Oligodendrocytes': '27.8', 'Microglial cells': '8.1', 'Muller glia cells': '17.5', 'Schwann cells': '0.038', 'Spermatogonia': '0.493', 'Spermatocytes': '0.039', 'Early spermatids': '-0.594', 'Late spermatids': '-0.605', 'Oocytes': '32.3', 'Cytotrophoblasts': '22.6', 'Syncytiotrophoblasts': '35.2', 'Extravillous trophoblasts': '16.9', 'Endothelial cells': '17.1', 'Lymphatic endothelial cells': '19.8', 'Cardiomyocytes': '0.606', 'Skeletal myocytes': '-0.267', 'Smooth muscle cells': '17.5', 'Adipocytes': '14.2', 'Melanocytes': '-0.044', 'Fibroblasts': '16.4', 'Peritubular cells': '0.501', 'Endometrial stromal cells': '23.1', 'Ovarian stromal cells': '26.2', 'Undifferentiated cells': '15.3', 'T-cells': '23.9', 'B-cells': '20.3', 'Plasma cells': '22.9', 'Nk-cells': '26.6', 'Granulocytes': '24.6', 'Monocytes': '45.7', 'Macrophages': '26.8', 'Hofbauer cells': '30.9', 'Kupffer cells': '25.9', 'Dendritic cells': '35.1', 'Langerhans cells': '0.063', 'Erythroid cells': '0.132', 'Adipocytes (Subcutaneous)': '-0.097', 'Adipocytes (Visceral)': '0.011', 'Breast glandular cells (progenitors)': '0.354', 'Adipocytes (Breast)': '-0.267', 'Colon enterocytes': '-0.051', 'Colon enteroendocrine cells': '0.220', 'Enteric glia cells': '-0.165', 'Mitotic cells (Colon)': '-0.150', 'Mitotic cells (Heart)': '0.480', 'Podocytes': '-0.181', 'Ascending Loop of Henle cells': '0.474', 'Intercalated cells': '-0.080', 'Cholangiocyte': '0.103', 'NK-cells (Liver)': '-0.128', 'Respiratory ciliated cells': '-0.039', 'Mitotic cells (Lung)': '-0.038', 'NK-cells (Lung)': '-0.064', 'B-cells (Lung)': '-0.111', 'Alpha cells': '0.404', 'Beta cells': '0.305', 'Prostate glandular cells': '0.130', 'Prostate basal glandular cells': '0.161', 'Urothelial cells': '0.014', 'Keratinocyte (other)': '-0.252', 'Keratinocyte (granular)': '0.069', 'Hair cortex cells': '0.100', 'Inner root sheath cells': '0.089', 'Outer root sheath cells': '0.181', 'Sebaceous gland cells': '0.154', 'Eccrine sweat gland cells': '0.132', 'Adipocytes (Skin)': '0.262', 'Mitotic cells (Skin)': '0.084', 'Parietal cells': '-0.246', 'Chief cells': '-0.218', 'Gastric mucous cells': '0.034', 'Gastric enteroendocrine cells': '-0.113', 'Mitotic cells (Stomach)': '0.245', 'Parafollicular cells': '0.063', 'Thyroid glandular cells': '0.216', 'Mitotic cells (Thyroid)': '-0.072', 'Adrenal cortex cells': '0.332', 'Adrenal medulla cells': '0.013', 'Mitotic cells (Adrenal gland)': '0.151', 'Minor salivary glandular cells': '0.601', 'Minor salivary gland ductal cells': '0.239', 'Minor salivary gland basal cells': '0.034', 'Mitotic cells (Minor salivary gland)': '0.064', 'Adipocytes (Minor salivary gland)': '0.090', 'Somatotropes': '-0.073', 'Lactotropes': '-0.015', 'Gonadotropes': '0.135', 'Corticotropes': '0.120', 'Thyrotropes': '0.137', 'Undifferentiated cells (Pituitary gland)': '0.061', 'Mitotic cells (Spleen)': '-0.268', 'Platelets': '0.097', 'Erythrocytes': '-0.083', 'Hematopoietic stem cells': '0.010', 'B-cells (Spleen)': '0.161', 'NK-cells (Spleen)': '0.267', 'Amygdala excitatory': '55.7', 'Cerebellar inhibitory': '41.8', 'Cge interneuron': '44.5', 'Deep-layer corticothalamic and 6b': '52.9', 'Deep-layer intratelencephalic': '61.2', 'Deep-layer near-projecting': '52.8', 'Eccentric medium spiny neuron': '55.0', 'Hippocampal ca1-3': '50.5', 'Hippocampal ca4': '51.7', 'Hippocampal dentate gyrus': '52.4', 'Lamp5-lhx6 and chandelier': '50.8', 'Lower rhombic lip': '29.3', 'Mammillary body': '41.7', 'Medium spiny neuron': '57.4', 'Mge interneuron': '51.2', 'Midbrain-derived inhibitory': '44.4', 'Miscellaneous': '51.4', 'Splatter': '39.1', 'Thalamic excitatory': '34.9', 'Upper rhombic lip': '43.3', 'Upper-layer intratelencephalic': '66.8', 'Astrocyte': '70.1', 'Bergmann glia': '64.7', 'Central nervous system macrophage': '64.0', 'Choroid plexus epithelial cell': '56.9', 'Committed oligodendrocyte precursor': '60.0', 'Ependymal cell': '36.6', 'Oligodendrocyte': '73.5', 'Oligodendrocyte precursor cell': '49.3', 'Endothelial cell': '40.4', 'Pericyte': '39.5', 'Vascular associated smooth muscle cell': '31.8', 'Fibroblast': '34.1', 'Leukocyte': '45.5', 'Basophil': '22.6', 'Eosinophil': '3.8', 'Neutrophil': '72.6', 'Classical monocyte': '22.2', 'Non-classical monocyte': '22.4', 'Intermediate monocyte': '32.9', 'T-reg': '12.1', 'GdT-cell': '2.6', 'MAIT T-cell': '15.4', 'Memory CD4 T-cell': '1.4', 'Naive CD4 T-cell': '12.5', 'Memory CD8 T-cell': '2.3', 'Naive CD8 T-cell': '15.5', 'Memory B-cell': '1.4', 'Naive B-cell': '7.5', 'Plasmacytoid DC': '15.8', 'Myeloid DC': '26.7', 'NK-cell': '16.2', 'Total PBMC': '15.5', 'Vd2 gdTCR': '13.6', 'Memory CD4 T-cell Th1\\/Th17': '11.4', 'Memory CD4 T-cell Th17': '15.2', 'Memory CD4 T-cell Th2': '15.8', 'Non-Vd2 gdTCR': '17.9', 'Memory CD4 T-cell Th1': '18.1', 'Memory CD4 T-cell TFH': '23.0', 'Terminal effector memory CD4 T-cell': '19.9', 'Central memory CD8 T-cell': '18.9', 'Effector memory CD8 T-cell': '17.1', 'Terminal effector memory CD8 T-cell': '14.3', 'Non-switched memory B-cell': '16.3', 'Plasmablast': '17.4', 'Switched memory B-cell': '13.5', 'Exhausted memory B-cell': '12.1', 'Progenitor cell': '16.1', 'Memory T-reg': '23.0', 'Naive CD4 T-cell activated': '11.8', 'Naive CD8 T-cell activated': '12.8', 'Naive T-reg': '14.4'}
null
{'Adipose Tissue': 23.757706810631227, 'Adrenal Gland': 27.17916279069767, 'Bladder': 31.29714285714286, 'Blood': 38.28341657696448, 'Blood Vessel': 33.74137078651685, 'Brain': 31.403220666161996, 'Breast': 25.240980392156864, 'Cervix Uteri': 37.55, 'Colon': 28.16311296534018, 'Esophagus': 26.20760207612457, 'Fallopian Tube': 44.36333333333333, 'Heart': 12.142481649245063, 'Kidney': 16.2118202247191, 'Liver': 21.567106194690265, 'Lung': 37.84491349480969, 'Muscle': 21.341774595267747, 'Nerve': 35.284281098546046, 'Ovary': 40.48966666666667, 'Pancreas': 12.588317073170732, 'Pituitary': 38.38303886925795, 'Prostate': 36.27465306122449, 'Salivary Gland': 22.95962962962963, 'Skin': 23.25537037037037, 'Small Intestine': 28.555989304812837, 'Spleen': 40.671659751037346, 'Stomach': 27.189523676880224, 'Testis': 25.782465373961216, 'Thyroid': 39.19149310872894, 'Uterus': 48.45549295774648, 'Vagina': 25.632724358974357}
TSG101
MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPPNPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRWRMKEEMDRAQAELNALKRTEEDLKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFLKHVRLLSRKQFQLRALMQKARKTAGLSDLY
Homo sapiens
Cytoplasm, Early endosome membrane, Late endosome membrane, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Midbody, Midbody ring, Nucleus
Low tissue specificity
{'Ciliated cells': '76.6', 'Basal respiratory cells': '154.8', 'Club cells': '77.9', 'Ionocytes': '111.5', 'Mucus glandular cells': '42.7', 'Serous glandular cells': '42.8', 'Gastric mucus-secreting cells': '33.0', 'Proximal enterocytes': '74.9', 'Paneth cells': '66.3', 'Distal enterocytes': '81.3', 'Intestinal goblet cells': '69.5', 'Exocrine glandular cells': '-0.679', 'Basal prostatic cells': '50.6', 'Prostatic glandular cells': '39.4', 'Breast glandular cells': '0.407', 'Breast myoepithelial cells': '0.337', 'Glandular and luminal cells': '53.1', 'Secretory cells': '83.8', 'Basal keratinocytes': '44.7', 'Suprabasal keratinocytes': '71.8', 'Basal squamous epithelial cells': '26.6', 'Squamous epithelial cells': '33.4', 'Alveolar cells type 1': '0.231', 'Alveolar cells type 2': '0.112', 'Salivary duct cells': '43.0', 'Ductal cells': '0.557', 'Hepatocytes': '0.430', 'Cholangiocytes': '36.2', 'Proximal tubular cells': '0.211', 'Distal tubular cells': '110.6', 'Collecting duct cells': '54.5', 'Mesothelial cells': '0.321', 'Sertoli cells': '0.290', 'Granulosa cells': '64.0', 'Enteroendocrine cells': '59.4', 'Pancreatic endocrine cells': '79.8', 'Leydig cells': '0.293', 'Excitatory neurons': '28.1', 'Inhibitory neurons': '27.2', 'Cone photoreceptor cells': '52.7', 'Rod photoreceptor cells': '34.9', 'Bipolar cells': '37.7', 'Horizontal cells': '14.5', 'Astrocytes': '21.7', 'Oligodendrocyte precursor cells': '30.2', 'Oligodendrocytes': '30.6', 'Microglial cells': '25.0', 'Muller glia cells': '76.9', 'Schwann cells': '0.059', 'Spermatogonia': '0.664', 'Spermatocytes': '0.740', 'Early spermatids': '0.154', 'Late spermatids': '-0.283', 'Oocytes': '544.1', 'Cytotrophoblasts': '193.8', 'Syncytiotrophoblasts': '330.4', 'Extravillous trophoblasts': '116.4', 'Endothelial cells': '50.1', 'Lymphatic endothelial cells': '50.4', 'Cardiomyocytes': '0.680', 'Skeletal myocytes': '-0.218', 'Smooth muscle cells': '47.9', 'Adipocytes': '59.2', 'Melanocytes': '0.263', 'Fibroblasts': '51.8', 'Peritubular cells': '0.169', 'Endometrial stromal cells': '36.6', 'Ovarian stromal cells': '56.7', 'Undifferentiated cells': '54.1', 'T-cells': '36.7', 'B-cells': '38.8', 'Plasma cells': '46.6', 'Nk-cells': '45.6', 'Granulocytes': '58.2', 'Monocytes': '75.7', 'Macrophages': '47.7', 'Hofbauer cells': '75.5', 'Kupffer cells': '36.2', 'Dendritic cells': '30.6', 'Langerhans cells': '0.304', 'Erythroid cells': '0.003', 'Adipocytes (Subcutaneous)': '0.048', 'Adipocytes (Visceral)': '-0.146', 'Breast glandular cells (progenitors)': '0.233', 'Adipocytes (Breast)': '-0.374', 'Colon enterocytes': '-0.132', 'Colon enteroendocrine cells': '0.268', 'Enteric glia cells': '0.054', 'Mitotic cells (Colon)': '-0.085', 'Mitotic cells (Heart)': '0.482', 'Podocytes': '0.085', 'Ascending Loop of Henle cells': '0.394', 'Intercalated cells': '0.108', 'Cholangiocyte': '0.392', 'NK-cells (Liver)': '-0.330', 'Respiratory ciliated cells': '0.031', 'Mitotic cells (Lung)': '0.037', 'NK-cells (Lung)': '-0.023', 'B-cells (Lung)': '-0.246', 'Alpha cells': '0.364', 'Beta cells': '0.171', 'Prostate glandular cells': '0.002', 'Prostate basal glandular cells': '0.198', 'Urothelial cells': '0.048', 'Keratinocyte (other)': '0.401', 'Keratinocyte (granular)': '0.097', 'Hair cortex cells': '-0.086', 'Inner root sheath cells': '-0.011', 'Outer root sheath cells': '0.012', 'Sebaceous gland cells': '0.000', 'Eccrine sweat gland cells': '-0.135', 'Adipocytes (Skin)': '-0.190', 'Mitotic cells (Skin)': '0.308', 'Parietal cells': '-0.348', 'Chief cells': '-0.297', 'Gastric mucous cells': '-0.056', 'Gastric enteroendocrine cells': '-0.228', 'Mitotic cells (Stomach)': '0.227', 'Parafollicular cells': '0.179', 'Thyroid glandular cells': '0.518', 'Mitotic cells (Thyroid)': '-0.080', 'Adrenal cortex cells': '0.621', 'Adrenal medulla cells': '0.070', 'Mitotic cells (Adrenal gland)': '0.424', 'Minor salivary glandular cells': '0.325', 'Minor salivary gland ductal cells': '-0.223', 'Minor salivary gland basal cells': '0.624', 'Mitotic cells (Minor salivary gland)': '0.677', 'Adipocytes (Minor salivary gland)': '0.211', 'Somatotropes': '-0.122', 'Lactotropes': '0.129', 'Gonadotropes': '0.182', 'Corticotropes': '0.031', 'Thyrotropes': '0.333', 'Undifferentiated cells (Pituitary gland)': '0.223', 'Mitotic cells (Spleen)': '-0.265', 'Platelets': '-0.146', 'Erythrocytes': '-0.135', 'Hematopoietic stem cells': '-0.167', 'B-cells (Spleen)': '0.240', 'NK-cells (Spleen)': '0.191', 'Amygdala excitatory': '58.6', 'Cerebellar inhibitory': '50.7', 'Cge interneuron': '53.8', 'Deep-layer corticothalamic and 6b': '55.2', 'Deep-layer intratelencephalic': '59.7', 'Deep-layer near-projecting': '50.9', 'Eccentric medium spiny neuron': '56.7', 'Hippocampal ca1-3': '53.6', 'Hippocampal ca4': '53.0', 'Hippocampal dentate gyrus': '49.5', 'Lamp5-lhx6 and chandelier': '52.8', 'Lower rhombic lip': '58.0', 'Mammillary body': '55.0', 'Medium spiny neuron': '54.9', 'Mge interneuron': '58.0', 'Midbrain-derived inhibitory': '53.1', 'Miscellaneous': '55.0', 'Splatter': '52.7', 'Thalamic excitatory': '50.3', 'Upper rhombic lip': '61.3', 'Upper-layer intratelencephalic': '56.0', 'Astrocyte': '44.8', 'Bergmann glia': '62.2', 'Central nervous system macrophage': '71.4', 'Choroid plexus epithelial cell': '46.9', 'Committed oligodendrocyte precursor': '54.8', 'Ependymal cell': '42.0', 'Oligodendrocyte': '56.1', 'Oligodendrocyte precursor cell': '59.4', 'Endothelial cell': '70.1', 'Pericyte': '79.1', 'Vascular associated smooth muscle cell': '44.4', 'Fibroblast': '67.0', 'Leukocyte': '62.1', 'Basophil': '155.5', 'Eosinophil': '156.0', 'Neutrophil': '285.5', 'Classical monocyte': '41.9', 'Non-classical monocyte': '65.1', 'Intermediate monocyte': '174.9', 'T-reg': '84.9', 'GdT-cell': '50.5', 'MAIT T-cell': '94.8', 'Memory CD4 T-cell': '48.1', 'Naive CD4 T-cell': '31.9', 'Memory CD8 T-cell': '53.9', 'Naive CD8 T-cell': '25.9', 'Memory B-cell': '78.8', 'Naive B-cell': '37.4', 'Plasmacytoid DC': '170.4', 'Myeloid DC': '149.9', 'NK-cell': '33.9', 'Total PBMC': '121.4', 'Vd2 gdTCR': '85.3', 'Memory CD4 T-cell Th1\\/Th17': '29.8', 'Memory CD4 T-cell Th17': '26.5', 'Memory CD4 T-cell Th2': '27.5', 'Non-Vd2 gdTCR': '93.4', 'Memory CD4 T-cell Th1': '28.8', 'Memory CD4 T-cell TFH': '27.5', 'Terminal effector memory CD4 T-cell': '90.5', 'Central memory CD8 T-cell': '74.3', 'Effector memory CD8 T-cell': '111.4', 'Terminal effector memory CD8 T-cell': '88.3', 'Non-switched memory B-cell': '107.9', 'Plasmablast': '231.8', 'Switched memory B-cell': '112.8', 'Exhausted memory B-cell': '104.0', 'Progenitor cell': '102.9', 'Memory T-reg': '33.7', 'Naive CD4 T-cell activated': '37.1', 'Naive CD8 T-cell activated': '43.6', 'Naive T-reg': '31.2'}
1KPP, 1KPQ, 1M4P, 1M4Q, 1S1Q, 2F0R, 3IV1, 3OBQ, 3OBS, 3OBU, 3OBX, 3P9G, 3P9H, 4EJE, 4YC1, 4ZNY, 5VKG, 6UD0, 6VME, 7NLC, 7ZLX
{'Adipose Tissue': 40.35773255813953, 'Adrenal Gland': 38.5276007751938, 'Bladder': 40.40238095238095, 'Blood': 28.832810548977395, 'Blood Vessel': 47.73047940074907, 'Brain': 23.41204617713853, 'Breast': 42.66856209150327, 'Cervix Uteri': 45.66315789473684, 'Colon': 35.0192811296534, 'Esophagus': 39.83753633217993, 'Fallopian Tube': 43.99111111111111, 'Heart': 21.577305458768876, 'Kidney': 30.484494382022472, 'Liver': 15.725243362831858, 'Lung': 41.149134948096886, 'Muscle': 36.61483188044832, 'Nerve': 51.607382875605815, 'Ovary': 43.63311111111111, 'Pancreas': 14.873387195121952, 'Pituitary': 41.152226148409895, 'Prostate': 35.90995918367347, 'Salivary Gland': 36.315493827160495, 'Skin': 44.65422885572139, 'Small Intestine': 31.754491978609625, 'Spleen': 33.57431535269709, 'Stomach': 30.618133704735374, 'Testis': 55.02772853185595, 'Thyroid': 45.608376722817766, 'Uterus': 45.90802816901409, 'Vagina': 48.97602564102564}
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RING finger
null
null
null
MC1R, MC4R, TSG101, PRNP
TSG101
mono
null
UBE2H, UBE2G1, UBE2D1
null
null
65.545199
0.575996
82.558051
0.54759
2,010
O60337
O60337
15673284
UbiBrowser
MARCHF6
MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '96.0', 'Basal respiratory cells': '52.0', 'Club cells': '60.0', 'Ionocytes': '63.0', 'Mucus glandular cells': '73.0', 'Serous glandular cells': '36.4', 'Gastric mucus-secreting cells': '58.4', 'Proximal enterocytes': '103.8', 'Paneth cells': '59.2', 'Distal enterocytes': '65.1', 'Intestinal goblet cells': '69.6', 'Exocrine glandular cells': '-0.573', 'Basal prostatic cells': '55.8', 'Prostatic glandular cells': '64.5', 'Breast glandular cells': '0.600', 'Breast myoepithelial cells': '0.546', 'Glandular and luminal cells': '78.6', 'Secretory cells': '56.2', 'Basal keratinocytes': '101.2', 'Suprabasal keratinocytes': '87.1', 'Basal squamous epithelial cells': '40.3', 'Squamous epithelial cells': '38.7', 'Alveolar cells type 1': '0.262', 'Alveolar cells type 2': '-0.058', 'Salivary duct cells': '57.4', 'Ductal cells': '0.463', 'Hepatocytes': '0.411', 'Cholangiocytes': '57.2', 'Proximal tubular cells': '0.180', 'Distal tubular cells': '15.4', 'Collecting duct cells': '75.8', 'Mesothelial cells': '0.335', 'Sertoli cells': '0.438', 'Granulosa cells': '55.5', 'Enteroendocrine cells': '64.6', 'Pancreatic endocrine cells': '28.9', 'Leydig cells': '0.533', 'Excitatory neurons': '148.7', 'Inhibitory neurons': '158.9', 'Cone photoreceptor cells': '57.8', 'Rod photoreceptor cells': '78.2', 'Bipolar cells': '92.8', 'Horizontal cells': '100.7', 'Astrocytes': '113.9', 'Oligodendrocyte precursor cells': '132.5', 'Oligodendrocytes': '141.7', 'Microglial cells': '73.4', 'Muller glia cells': '49.8', 'Schwann cells': '0.284', 'Spermatogonia': '0.606', 'Spermatocytes': '0.538', 'Early spermatids': '-0.163', 'Late spermatids': '-0.622', 'Oocytes': '24.3', 'Cytotrophoblasts': '51.7', 'Syncytiotrophoblasts': '83.1', 'Extravillous trophoblasts': '29.9', 'Endothelial cells': '56.4', 'Lymphatic endothelial cells': '48.0', 'Cardiomyocytes': '0.639', 'Skeletal myocytes': '-0.247', 'Smooth muscle cells': '62.3', 'Adipocytes': '57.1', 'Melanocytes': '-0.052', 'Fibroblasts': '58.4', 'Peritubular cells': '0.453', 'Endometrial stromal cells': '54.9', 'Ovarian stromal cells': '59.6', 'Undifferentiated cells': '53.5', 'T-cells': '60.2', 'B-cells': '67.9', 'Plasma cells': '62.1', 'Nk-cells': '59.0', 'Granulocytes': '67.8', 'Monocytes': '84.1', 'Macrophages': '46.1', 'Hofbauer cells': '36.3', 'Kupffer cells': '59.1', 'Dendritic cells': '52.5', 'Langerhans cells': '-0.003', 'Erythroid cells': '0.056', 'Adipocytes (Subcutaneous)': '0.136', 'Adipocytes (Visceral)': '-0.155', 'Breast glandular cells (progenitors)': '0.406', 'Adipocytes (Breast)': '-0.500', 'Colon enterocytes': '0.058', 'Colon enteroendocrine cells': '0.264', 'Enteric glia cells': '0.112', 'Mitotic cells (Colon)': '0.116', 'Mitotic cells (Heart)': '0.464', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.412', 'Intercalated cells': '-0.089', 'Cholangiocyte': '0.287', 'NK-cells (Liver)': '-0.215', 'Respiratory ciliated cells': '0.173', 'Mitotic cells (Lung)': '-0.162', 'NK-cells (Lung)': '0.254', 'B-cells (Lung)': '0.166', 'Alpha cells': '0.359', 'Beta cells': '0.223', 'Prostate glandular cells': '-0.043', 'Prostate basal glandular cells': '0.321', 'Urothelial cells': '0.224', 'Keratinocyte (other)': '-0.062', 'Keratinocyte (granular)': '-0.047', 'Hair cortex cells': '-0.087', 'Inner root sheath cells': '-0.055', 'Outer root sheath cells': '0.031', 'Sebaceous gland cells': '-0.014', 'Eccrine sweat gland cells': '0.022', 'Adipocytes (Skin)': '0.070', 'Mitotic cells (Skin)': '-0.001', 'Parietal cells': '0.002', 'Chief cells': '-0.047', 'Gastric mucous cells': '0.235', 'Gastric enteroendocrine cells': '0.064', 'Mitotic cells (Stomach)': '0.157', 'Parafollicular cells': '0.069', 'Thyroid glandular cells': '0.406', 'Mitotic cells (Thyroid)': '-0.033', 'Adrenal cortex cells': '0.529', 'Adrenal medulla cells': '0.161', 'Mitotic cells (Adrenal gland)': '0.238', 'Minor salivary glandular cells': '0.634', 'Minor salivary gland ductal cells': '0.327', 'Minor salivary gland basal cells': '0.051', 'Mitotic cells (Minor salivary gland)': '0.025', 'Adipocytes (Minor salivary gland)': '0.093', 'Somatotropes': '-0.142', 'Lactotropes': '-0.039', 'Gonadotropes': '0.109', 'Corticotropes': '-0.097', 'Thyrotropes': '0.091', 'Undifferentiated cells (Pituitary gland)': '0.279', 'Mitotic cells (Spleen)': '-0.204', 'Platelets': '-0.089', 'Erythrocytes': '-0.132', 'Hematopoietic stem cells': '-0.196', 'B-cells (Spleen)': '0.425', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '192.6', 'Cerebellar inhibitory': '215.3', 'Cge interneuron': '263.0', 'Deep-layer corticothalamic and 6b': '200.6', 'Deep-layer intratelencephalic': '197.0', 'Deep-layer near-projecting': '209.5', 'Eccentric medium spiny neuron': '222.1', 'Hippocampal ca1-3': '209.0', 'Hippocampal ca4': '169.4', 'Hippocampal dentate gyrus': '211.4', 'Lamp5-lhx6 and chandelier': '238.8', 'Lower rhombic lip': '177.0', 'Mammillary body': '191.3', 'Medium spiny neuron': '180.7', 'Mge interneuron': '213.3', 'Midbrain-derived inhibitory': '207.1', 'Miscellaneous': '208.1', 'Splatter': '198.1', 'Thalamic excitatory': '199.0', 'Upper rhombic lip': '221.2', 'Upper-layer intratelencephalic': '211.3', 'Astrocyte': '231.4', 'Bergmann glia': '165.8', 'Central nervous system macrophage': '196.0', 'Choroid plexus epithelial cell': '160.2', 'Committed oligodendrocyte precursor': '150.5', 'Ependymal cell': '357.9', 'Oligodendrocyte': '230.6', 'Oligodendrocyte precursor cell': '197.8', 'Endothelial cell': '245.6', 'Pericyte': '186.9', 'Vascular associated smooth muscle cell': '193.1', 'Fibroblast': '219.2', 'Leukocyte': '230.5', 'Basophil': '108.6', 'Eosinophil': '12.6', 'Neutrophil': '123.2', 'Classical monocyte': '69.4', 'Non-classical monocyte': '100.2', 'Intermediate monocyte': '58.9', 'T-reg': '83.5', 'GdT-cell': '11.2', 'MAIT T-cell': '89.9', 'Memory CD4 T-cell': '10.8', 'Naive CD4 T-cell': '181.5', 'Memory CD8 T-cell': '11.0', 'Naive CD8 T-cell': '172.1', 'Memory B-cell': '11.7', 'Naive B-cell': '169.6', 'Plasmacytoid DC': '39.4', 'Myeloid DC': '56.9', 'NK-cell': '112.5', 'Total PBMC': '60.1', 'Vd2 gdTCR': '78.2', 'Memory CD4 T-cell Th1\\/Th17': '171.5', 'Memory CD4 T-cell Th17': '154.0', 'Memory CD4 T-cell Th2': '170.0', 'Non-Vd2 gdTCR': '93.3', 'Memory CD4 T-cell Th1': '146.3', 'Memory CD4 T-cell TFH': '137.9', 'Terminal effector memory CD4 T-cell': '88.0', 'Central memory CD8 T-cell': '87.5', 'Effector memory CD8 T-cell': '84.2', 'Terminal effector memory CD8 T-cell': '79.9', 'Non-switched memory B-cell': '81.3', 'Plasmablast': '112.1', 'Switched memory B-cell': '79.4', 'Exhausted memory B-cell': '75.4', 'Progenitor cell': '95.1', 'Memory T-reg': '138.0', 'Naive CD4 T-cell activated': '119.2', 'Naive CD8 T-cell activated': '110.0', 'Naive T-reg': '199.9'}
null
{'Adipose Tissue': 36.31873754152824, 'Adrenal Gland': 25.83708914728682, 'Bladder': 37.19904761904762, 'Blood': 21.980406889128098, 'Blood Vessel': 41.85550561797753, 'Brain': 29.084541635124904, 'Breast': 42.736405228758166, 'Cervix Uteri': 48.53578947368421, 'Colon': 33.41946598202824, 'Esophagus': 28.81244567474048, 'Fallopian Tube': 59.346666666666664, 'Heart': 15.93619512195122, 'Kidney': 20.683662921348315, 'Liver': 14.074880530973452, 'Lung': 49.03328719723184, 'Muscle': 34.10750435865504, 'Nerve': 53.29239095315024, 'Ovary': 65.94533333333334, 'Pancreas': 23.688786585365857, 'Pituitary': 42.42575971731448, 'Prostate': 36.94277551020408, 'Salivary Gland': 36.87234567901234, 'Skin': 41.76371475953565, 'Small Intestine': 48.07802139037433, 'Spleen': 39.45315352697095, 'Stomach': 31.6258495821727, 'Testis': 30.937534626038783, 'Thyroid': 54.50356814701379, 'Uterus': 57.17781690140845, 'Vagina': 39.84307692307693}
MARCHF6
MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '96.0', 'Basal respiratory cells': '52.0', 'Club cells': '60.0', 'Ionocytes': '63.0', 'Mucus glandular cells': '73.0', 'Serous glandular cells': '36.4', 'Gastric mucus-secreting cells': '58.4', 'Proximal enterocytes': '103.8', 'Paneth cells': '59.2', 'Distal enterocytes': '65.1', 'Intestinal goblet cells': '69.6', 'Exocrine glandular cells': '-0.573', 'Basal prostatic cells': '55.8', 'Prostatic glandular cells': '64.5', 'Breast glandular cells': '0.600', 'Breast myoepithelial cells': '0.546', 'Glandular and luminal cells': '78.6', 'Secretory cells': '56.2', 'Basal keratinocytes': '101.2', 'Suprabasal keratinocytes': '87.1', 'Basal squamous epithelial cells': '40.3', 'Squamous epithelial cells': '38.7', 'Alveolar cells type 1': '0.262', 'Alveolar cells type 2': '-0.058', 'Salivary duct cells': '57.4', 'Ductal cells': '0.463', 'Hepatocytes': '0.411', 'Cholangiocytes': '57.2', 'Proximal tubular cells': '0.180', 'Distal tubular cells': '15.4', 'Collecting duct cells': '75.8', 'Mesothelial cells': '0.335', 'Sertoli cells': '0.438', 'Granulosa cells': '55.5', 'Enteroendocrine cells': '64.6', 'Pancreatic endocrine cells': '28.9', 'Leydig cells': '0.533', 'Excitatory neurons': '148.7', 'Inhibitory neurons': '158.9', 'Cone photoreceptor cells': '57.8', 'Rod photoreceptor cells': '78.2', 'Bipolar cells': '92.8', 'Horizontal cells': '100.7', 'Astrocytes': '113.9', 'Oligodendrocyte precursor cells': '132.5', 'Oligodendrocytes': '141.7', 'Microglial cells': '73.4', 'Muller glia cells': '49.8', 'Schwann cells': '0.284', 'Spermatogonia': '0.606', 'Spermatocytes': '0.538', 'Early spermatids': '-0.163', 'Late spermatids': '-0.622', 'Oocytes': '24.3', 'Cytotrophoblasts': '51.7', 'Syncytiotrophoblasts': '83.1', 'Extravillous trophoblasts': '29.9', 'Endothelial cells': '56.4', 'Lymphatic endothelial cells': '48.0', 'Cardiomyocytes': '0.639', 'Skeletal myocytes': '-0.247', 'Smooth muscle cells': '62.3', 'Adipocytes': '57.1', 'Melanocytes': '-0.052', 'Fibroblasts': '58.4', 'Peritubular cells': '0.453', 'Endometrial stromal cells': '54.9', 'Ovarian stromal cells': '59.6', 'Undifferentiated cells': '53.5', 'T-cells': '60.2', 'B-cells': '67.9', 'Plasma cells': '62.1', 'Nk-cells': '59.0', 'Granulocytes': '67.8', 'Monocytes': '84.1', 'Macrophages': '46.1', 'Hofbauer cells': '36.3', 'Kupffer cells': '59.1', 'Dendritic cells': '52.5', 'Langerhans cells': '-0.003', 'Erythroid cells': '0.056', 'Adipocytes (Subcutaneous)': '0.136', 'Adipocytes (Visceral)': '-0.155', 'Breast glandular cells (progenitors)': '0.406', 'Adipocytes (Breast)': '-0.500', 'Colon enterocytes': '0.058', 'Colon enteroendocrine cells': '0.264', 'Enteric glia cells': '0.112', 'Mitotic cells (Colon)': '0.116', 'Mitotic cells (Heart)': '0.464', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.412', 'Intercalated cells': '-0.089', 'Cholangiocyte': '0.287', 'NK-cells (Liver)': '-0.215', 'Respiratory ciliated cells': '0.173', 'Mitotic cells (Lung)': '-0.162', 'NK-cells (Lung)': '0.254', 'B-cells (Lung)': '0.166', 'Alpha cells': '0.359', 'Beta cells': '0.223', 'Prostate glandular cells': '-0.043', 'Prostate basal glandular cells': '0.321', 'Urothelial cells': '0.224', 'Keratinocyte (other)': '-0.062', 'Keratinocyte (granular)': '-0.047', 'Hair cortex cells': '-0.087', 'Inner root sheath cells': '-0.055', 'Outer root sheath cells': '0.031', 'Sebaceous gland cells': '-0.014', 'Eccrine sweat gland cells': '0.022', 'Adipocytes (Skin)': '0.070', 'Mitotic cells (Skin)': '-0.001', 'Parietal cells': '0.002', 'Chief cells': '-0.047', 'Gastric mucous cells': '0.235', 'Gastric enteroendocrine cells': '0.064', 'Mitotic cells (Stomach)': '0.157', 'Parafollicular cells': '0.069', 'Thyroid glandular cells': '0.406', 'Mitotic cells (Thyroid)': '-0.033', 'Adrenal cortex cells': '0.529', 'Adrenal medulla cells': '0.161', 'Mitotic cells (Adrenal gland)': '0.238', 'Minor salivary glandular cells': '0.634', 'Minor salivary gland ductal cells': '0.327', 'Minor salivary gland basal cells': '0.051', 'Mitotic cells (Minor salivary gland)': '0.025', 'Adipocytes (Minor salivary gland)': '0.093', 'Somatotropes': '-0.142', 'Lactotropes': '-0.039', 'Gonadotropes': '0.109', 'Corticotropes': '-0.097', 'Thyrotropes': '0.091', 'Undifferentiated cells (Pituitary gland)': '0.279', 'Mitotic cells (Spleen)': '-0.204', 'Platelets': '-0.089', 'Erythrocytes': '-0.132', 'Hematopoietic stem cells': '-0.196', 'B-cells (Spleen)': '0.425', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '192.6', 'Cerebellar inhibitory': '215.3', 'Cge interneuron': '263.0', 'Deep-layer corticothalamic and 6b': '200.6', 'Deep-layer intratelencephalic': '197.0', 'Deep-layer near-projecting': '209.5', 'Eccentric medium spiny neuron': '222.1', 'Hippocampal ca1-3': '209.0', 'Hippocampal ca4': '169.4', 'Hippocampal dentate gyrus': '211.4', 'Lamp5-lhx6 and chandelier': '238.8', 'Lower rhombic lip': '177.0', 'Mammillary body': '191.3', 'Medium spiny neuron': '180.7', 'Mge interneuron': '213.3', 'Midbrain-derived inhibitory': '207.1', 'Miscellaneous': '208.1', 'Splatter': '198.1', 'Thalamic excitatory': '199.0', 'Upper rhombic lip': '221.2', 'Upper-layer intratelencephalic': '211.3', 'Astrocyte': '231.4', 'Bergmann glia': '165.8', 'Central nervous system macrophage': '196.0', 'Choroid plexus epithelial cell': '160.2', 'Committed oligodendrocyte precursor': '150.5', 'Ependymal cell': '357.9', 'Oligodendrocyte': '230.6', 'Oligodendrocyte precursor cell': '197.8', 'Endothelial cell': '245.6', 'Pericyte': '186.9', 'Vascular associated smooth muscle cell': '193.1', 'Fibroblast': '219.2', 'Leukocyte': '230.5', 'Basophil': '108.6', 'Eosinophil': '12.6', 'Neutrophil': '123.2', 'Classical monocyte': '69.4', 'Non-classical monocyte': '100.2', 'Intermediate monocyte': '58.9', 'T-reg': '83.5', 'GdT-cell': '11.2', 'MAIT T-cell': '89.9', 'Memory CD4 T-cell': '10.8', 'Naive CD4 T-cell': '181.5', 'Memory CD8 T-cell': '11.0', 'Naive CD8 T-cell': '172.1', 'Memory B-cell': '11.7', 'Naive B-cell': '169.6', 'Plasmacytoid DC': '39.4', 'Myeloid DC': '56.9', 'NK-cell': '112.5', 'Total PBMC': '60.1', 'Vd2 gdTCR': '78.2', 'Memory CD4 T-cell Th1\\/Th17': '171.5', 'Memory CD4 T-cell Th17': '154.0', 'Memory CD4 T-cell Th2': '170.0', 'Non-Vd2 gdTCR': '93.3', 'Memory CD4 T-cell Th1': '146.3', 'Memory CD4 T-cell TFH': '137.9', 'Terminal effector memory CD4 T-cell': '88.0', 'Central memory CD8 T-cell': '87.5', 'Effector memory CD8 T-cell': '84.2', 'Terminal effector memory CD8 T-cell': '79.9', 'Non-switched memory B-cell': '81.3', 'Plasmablast': '112.1', 'Switched memory B-cell': '79.4', 'Exhausted memory B-cell': '75.4', 'Progenitor cell': '95.1', 'Memory T-reg': '138.0', 'Naive CD4 T-cell activated': '119.2', 'Naive CD8 T-cell activated': '110.0', 'Naive T-reg': '199.9'}
null
{'Adipose Tissue': 36.31873754152824, 'Adrenal Gland': 25.83708914728682, 'Bladder': 37.19904761904762, 'Blood': 21.980406889128098, 'Blood Vessel': 41.85550561797753, 'Brain': 29.084541635124904, 'Breast': 42.736405228758166, 'Cervix Uteri': 48.53578947368421, 'Colon': 33.41946598202824, 'Esophagus': 28.81244567474048, 'Fallopian Tube': 59.346666666666664, 'Heart': 15.93619512195122, 'Kidney': 20.683662921348315, 'Liver': 14.074880530973452, 'Lung': 49.03328719723184, 'Muscle': 34.10750435865504, 'Nerve': 53.29239095315024, 'Ovary': 65.94533333333334, 'Pancreas': 23.688786585365857, 'Pituitary': 42.42575971731448, 'Prostate': 36.94277551020408, 'Salivary Gland': 36.87234567901234, 'Skin': 41.76371475953565, 'Small Intestine': 48.07802139037433, 'Spleen': 39.45315352697095, 'Stomach': 31.6258495821727, 'Testis': 30.937534626038783, 'Thyroid': 54.50356814701379, 'Uterus': 57.17781690140845, 'Vagina': 39.84307692307693}
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0.37, 0.46, 0.66, 0.4, 0.56, 0.47, 0.54, 0.61, 0.51, 0.5, 0.49, 0.39, 0.54, 0.59, 0.65, 0.59, 0.37, 0.48, 0.62, 0.63, 0.21, 0.32, 0.46, 0.56, 0.13, 0.22, 0.39, 0.68, 0.7, 0.11, 0.38, 0.7, 0.34, 0.53, 0.52, 0.04, 0.4, 0.37, 0.31, 0.88, 0.79, 0.91, 0.82, 0.75, 0.95, 0.91, 0.86, 0.91, 0.89, 0.91, 0.96, 0.92, 0.95, 0.95, 0.85, 0.95, 0.93, 1.0]
null
null
null
null
DIO2, SQLE
DIO2, SQLE
48
null
UBE2G1
null
null
77.54178
0.474495
77.54178
0.474495
629
O60337
Q14534
32170014
UbiNet, UbiBrowser
MARCHF6
MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '96.0', 'Basal respiratory cells': '52.0', 'Club cells': '60.0', 'Ionocytes': '63.0', 'Mucus glandular cells': '73.0', 'Serous glandular cells': '36.4', 'Gastric mucus-secreting cells': '58.4', 'Proximal enterocytes': '103.8', 'Paneth cells': '59.2', 'Distal enterocytes': '65.1', 'Intestinal goblet cells': '69.6', 'Exocrine glandular cells': '-0.573', 'Basal prostatic cells': '55.8', 'Prostatic glandular cells': '64.5', 'Breast glandular cells': '0.600', 'Breast myoepithelial cells': '0.546', 'Glandular and luminal cells': '78.6', 'Secretory cells': '56.2', 'Basal keratinocytes': '101.2', 'Suprabasal keratinocytes': '87.1', 'Basal squamous epithelial cells': '40.3', 'Squamous epithelial cells': '38.7', 'Alveolar cells type 1': '0.262', 'Alveolar cells type 2': '-0.058', 'Salivary duct cells': '57.4', 'Ductal cells': '0.463', 'Hepatocytes': '0.411', 'Cholangiocytes': '57.2', 'Proximal tubular cells': '0.180', 'Distal tubular cells': '15.4', 'Collecting duct cells': '75.8', 'Mesothelial cells': '0.335', 'Sertoli cells': '0.438', 'Granulosa cells': '55.5', 'Enteroendocrine cells': '64.6', 'Pancreatic endocrine cells': '28.9', 'Leydig cells': '0.533', 'Excitatory neurons': '148.7', 'Inhibitory neurons': '158.9', 'Cone photoreceptor cells': '57.8', 'Rod photoreceptor cells': '78.2', 'Bipolar cells': '92.8', 'Horizontal cells': '100.7', 'Astrocytes': '113.9', 'Oligodendrocyte precursor cells': '132.5', 'Oligodendrocytes': '141.7', 'Microglial cells': '73.4', 'Muller glia cells': '49.8', 'Schwann cells': '0.284', 'Spermatogonia': '0.606', 'Spermatocytes': '0.538', 'Early spermatids': '-0.163', 'Late spermatids': '-0.622', 'Oocytes': '24.3', 'Cytotrophoblasts': '51.7', 'Syncytiotrophoblasts': '83.1', 'Extravillous trophoblasts': '29.9', 'Endothelial cells': '56.4', 'Lymphatic endothelial cells': '48.0', 'Cardiomyocytes': '0.639', 'Skeletal myocytes': '-0.247', 'Smooth muscle cells': '62.3', 'Adipocytes': '57.1', 'Melanocytes': '-0.052', 'Fibroblasts': '58.4', 'Peritubular cells': '0.453', 'Endometrial stromal cells': '54.9', 'Ovarian stromal cells': '59.6', 'Undifferentiated cells': '53.5', 'T-cells': '60.2', 'B-cells': '67.9', 'Plasma cells': '62.1', 'Nk-cells': '59.0', 'Granulocytes': '67.8', 'Monocytes': '84.1', 'Macrophages': '46.1', 'Hofbauer cells': '36.3', 'Kupffer cells': '59.1', 'Dendritic cells': '52.5', 'Langerhans cells': '-0.003', 'Erythroid cells': '0.056', 'Adipocytes (Subcutaneous)': '0.136', 'Adipocytes (Visceral)': '-0.155', 'Breast glandular cells (progenitors)': '0.406', 'Adipocytes (Breast)': '-0.500', 'Colon enterocytes': '0.058', 'Colon enteroendocrine cells': '0.264', 'Enteric glia cells': '0.112', 'Mitotic cells (Colon)': '0.116', 'Mitotic cells (Heart)': '0.464', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.412', 'Intercalated cells': '-0.089', 'Cholangiocyte': '0.287', 'NK-cells (Liver)': '-0.215', 'Respiratory ciliated cells': '0.173', 'Mitotic cells (Lung)': '-0.162', 'NK-cells (Lung)': '0.254', 'B-cells (Lung)': '0.166', 'Alpha cells': '0.359', 'Beta cells': '0.223', 'Prostate glandular cells': '-0.043', 'Prostate basal glandular cells': '0.321', 'Urothelial cells': '0.224', 'Keratinocyte (other)': '-0.062', 'Keratinocyte (granular)': '-0.047', 'Hair cortex cells': '-0.087', 'Inner root sheath cells': '-0.055', 'Outer root sheath cells': '0.031', 'Sebaceous gland cells': '-0.014', 'Eccrine sweat gland cells': '0.022', 'Adipocytes (Skin)': '0.070', 'Mitotic cells (Skin)': '-0.001', 'Parietal cells': '0.002', 'Chief cells': '-0.047', 'Gastric mucous cells': '0.235', 'Gastric enteroendocrine cells': '0.064', 'Mitotic cells (Stomach)': '0.157', 'Parafollicular cells': '0.069', 'Thyroid glandular cells': '0.406', 'Mitotic cells (Thyroid)': '-0.033', 'Adrenal cortex cells': '0.529', 'Adrenal medulla cells': '0.161', 'Mitotic cells (Adrenal gland)': '0.238', 'Minor salivary glandular cells': '0.634', 'Minor salivary gland ductal cells': '0.327', 'Minor salivary gland basal cells': '0.051', 'Mitotic cells (Minor salivary gland)': '0.025', 'Adipocytes (Minor salivary gland)': '0.093', 'Somatotropes': '-0.142', 'Lactotropes': '-0.039', 'Gonadotropes': '0.109', 'Corticotropes': '-0.097', 'Thyrotropes': '0.091', 'Undifferentiated cells (Pituitary gland)': '0.279', 'Mitotic cells (Spleen)': '-0.204', 'Platelets': '-0.089', 'Erythrocytes': '-0.132', 'Hematopoietic stem cells': '-0.196', 'B-cells (Spleen)': '0.425', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '192.6', 'Cerebellar inhibitory': '215.3', 'Cge interneuron': '263.0', 'Deep-layer corticothalamic and 6b': '200.6', 'Deep-layer intratelencephalic': '197.0', 'Deep-layer near-projecting': '209.5', 'Eccentric medium spiny neuron': '222.1', 'Hippocampal ca1-3': '209.0', 'Hippocampal ca4': '169.4', 'Hippocampal dentate gyrus': '211.4', 'Lamp5-lhx6 and chandelier': '238.8', 'Lower rhombic lip': '177.0', 'Mammillary body': '191.3', 'Medium spiny neuron': '180.7', 'Mge interneuron': '213.3', 'Midbrain-derived inhibitory': '207.1', 'Miscellaneous': '208.1', 'Splatter': '198.1', 'Thalamic excitatory': '199.0', 'Upper rhombic lip': '221.2', 'Upper-layer intratelencephalic': '211.3', 'Astrocyte': '231.4', 'Bergmann glia': '165.8', 'Central nervous system macrophage': '196.0', 'Choroid plexus epithelial cell': '160.2', 'Committed oligodendrocyte precursor': '150.5', 'Ependymal cell': '357.9', 'Oligodendrocyte': '230.6', 'Oligodendrocyte precursor cell': '197.8', 'Endothelial cell': '245.6', 'Pericyte': '186.9', 'Vascular associated smooth muscle cell': '193.1', 'Fibroblast': '219.2', 'Leukocyte': '230.5', 'Basophil': '108.6', 'Eosinophil': '12.6', 'Neutrophil': '123.2', 'Classical monocyte': '69.4', 'Non-classical monocyte': '100.2', 'Intermediate monocyte': '58.9', 'T-reg': '83.5', 'GdT-cell': '11.2', 'MAIT T-cell': '89.9', 'Memory CD4 T-cell': '10.8', 'Naive CD4 T-cell': '181.5', 'Memory CD8 T-cell': '11.0', 'Naive CD8 T-cell': '172.1', 'Memory B-cell': '11.7', 'Naive B-cell': '169.6', 'Plasmacytoid DC': '39.4', 'Myeloid DC': '56.9', 'NK-cell': '112.5', 'Total PBMC': '60.1', 'Vd2 gdTCR': '78.2', 'Memory CD4 T-cell Th1\\/Th17': '171.5', 'Memory CD4 T-cell Th17': '154.0', 'Memory CD4 T-cell Th2': '170.0', 'Non-Vd2 gdTCR': '93.3', 'Memory CD4 T-cell Th1': '146.3', 'Memory CD4 T-cell TFH': '137.9', 'Terminal effector memory CD4 T-cell': '88.0', 'Central memory CD8 T-cell': '87.5', 'Effector memory CD8 T-cell': '84.2', 'Terminal effector memory CD8 T-cell': '79.9', 'Non-switched memory B-cell': '81.3', 'Plasmablast': '112.1', 'Switched memory B-cell': '79.4', 'Exhausted memory B-cell': '75.4', 'Progenitor cell': '95.1', 'Memory T-reg': '138.0', 'Naive CD4 T-cell activated': '119.2', 'Naive CD8 T-cell activated': '110.0', 'Naive T-reg': '199.9'}
null
{'Adipose Tissue': 36.31873754152824, 'Adrenal Gland': 25.83708914728682, 'Bladder': 37.19904761904762, 'Blood': 21.980406889128098, 'Blood Vessel': 41.85550561797753, 'Brain': 29.084541635124904, 'Breast': 42.736405228758166, 'Cervix Uteri': 48.53578947368421, 'Colon': 33.41946598202824, 'Esophagus': 28.81244567474048, 'Fallopian Tube': 59.346666666666664, 'Heart': 15.93619512195122, 'Kidney': 20.683662921348315, 'Liver': 14.074880530973452, 'Lung': 49.03328719723184, 'Muscle': 34.10750435865504, 'Nerve': 53.29239095315024, 'Ovary': 65.94533333333334, 'Pancreas': 23.688786585365857, 'Pituitary': 42.42575971731448, 'Prostate': 36.94277551020408, 'Salivary Gland': 36.87234567901234, 'Skin': 41.76371475953565, 'Small Intestine': 48.07802139037433, 'Spleen': 39.45315352697095, 'Stomach': 31.6258495821727, 'Testis': 30.937534626038783, 'Thyroid': 54.50356814701379, 'Uterus': 57.17781690140845, 'Vagina': 39.84307692307693}
SQLE
MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLSYRCRHRNGGLLGRQQSGSQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGLGDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAEPNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNKVSVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDIRGEMPRNLREYMVEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGGMTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSATDDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPWITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH
Homo sapiens
Microsome membrane, Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '97.8', 'Basal respiratory cells': '193.2', 'Club cells': '99.8', 'Ionocytes': '149.8', 'Mucus glandular cells': '9.4', 'Serous glandular cells': '39.3', 'Gastric mucus-secreting cells': '49.5', 'Proximal enterocytes': '20.1', 'Paneth cells': '28.2', 'Distal enterocytes': '102.4', 'Intestinal goblet cells': '48.1', 'Exocrine glandular cells': '-0.430', 'Basal prostatic cells': '12.1', 'Prostatic glandular cells': '36.8', 'Breast glandular cells': '0.501', 'Breast myoepithelial cells': '0.451', 'Glandular and luminal cells': '76.8', 'Secretory cells': '23.4', 'Basal keratinocytes': '66.1', 'Suprabasal keratinocytes': '226.4', 'Basal squamous epithelial cells': '23.3', 'Squamous epithelial cells': '79.5', 'Alveolar cells type 1': '-0.030', 'Alveolar cells type 2': '0.662', 'Salivary duct cells': '15.9', 'Ductal cells': '0.605', 'Hepatocytes': '0.146', 'Cholangiocytes': '40.1', 'Proximal tubular cells': '0.044', 'Distal tubular cells': '6.1', 'Collecting duct cells': '42.8', 'Mesothelial cells': '0.307', 'Sertoli cells': '0.103', 'Granulosa cells': '32.0', 'Enteroendocrine cells': '26.7', 'Pancreatic endocrine cells': '23.8', 'Leydig cells': '0.187', 'Excitatory neurons': '13.8', 'Inhibitory neurons': '17.9', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '65.5', 'Bipolar cells': '39.4', 'Horizontal cells': '107.6', 'Astrocytes': '20.4', 'Oligodendrocyte precursor cells': '18.9', 'Oligodendrocytes': '72.5', 'Microglial cells': '12.5', 'Muller glia cells': '19.4', 'Schwann cells': '0.032', 'Spermatogonia': '0.482', 'Spermatocytes': '0.831', 'Early spermatids': '0.275', 'Late spermatids': '-0.164', 'Oocytes': '79.4', 'Cytotrophoblasts': '103.9', 'Syncytiotrophoblasts': '297.5', 'Extravillous trophoblasts': '141.4', 'Endothelial cells': '31.2', 'Lymphatic endothelial cells': '29.6', 'Cardiomyocytes': '0.343', 'Skeletal myocytes': '0.050', 'Smooth muscle cells': '20.1', 'Adipocytes': '14.3', 'Melanocytes': '0.305', 'Fibroblasts': '21.6', 'Peritubular cells': '0.051', 'Endometrial stromal cells': '22.7', 'Ovarian stromal cells': '16.7', 'Undifferentiated cells': '29.8', 'T-cells': '18.5', 'B-cells': '26.8', 'Plasma cells': '37.2', 'Nk-cells': '16.3', 'Granulocytes': '35.9', 'Monocytes': '14.3', 'Macrophages': '20.9', 'Hofbauer cells': '49.1', 'Kupffer cells': '54.9', 'Dendritic cells': '12.7', 'Langerhans cells': '0.216', 'Erythroid cells': '0.133', 'Adipocytes (Subcutaneous)': '-0.282', 'Adipocytes (Visceral)': '-0.285', 'Breast glandular cells (progenitors)': '0.337', 'Adipocytes (Breast)': '-0.560', 'Colon enterocytes': '0.250', 'Colon enteroendocrine cells': '0.252', 'Enteric glia cells': '0.054', 'Mitotic cells (Colon)': '0.464', 'Mitotic cells (Heart)': '0.543', 'Podocytes': '0.049', 'Ascending Loop of Henle cells': '0.299', 'Intercalated cells': '0.052', 'Cholangiocyte': '0.037', 'NK-cells (Liver)': '0.044', 'Respiratory ciliated cells': '-0.001', 'Mitotic cells (Lung)': '0.196', 'NK-cells (Lung)': '-0.351', 'B-cells (Lung)': '-0.308', 'Alpha cells': '0.279', 'Beta cells': '0.194', 'Prostate glandular cells': '0.294', 'Prostate basal glandular cells': '0.002', 'Urothelial cells': '-0.114', 'Keratinocyte (other)': '0.468', 'Keratinocyte (granular)': '0.001', 'Hair cortex cells': '0.005', 'Inner root sheath cells': '0.097', 'Outer root sheath cells': '0.072', 'Sebaceous gland cells': '-0.056', 'Eccrine sweat gland cells': '-0.238', 'Adipocytes (Skin)': '-0.442', 'Mitotic cells (Skin)': '0.359', 'Parietal cells': '0.192', 'Chief cells': '0.236', 'Gastric mucous cells': '0.495', 'Gastric enteroendocrine cells': '0.267', 'Mitotic cells (Stomach)': '0.517', 'Parafollicular cells': '0.090', 'Thyroid glandular cells': '0.351', 'Mitotic cells (Thyroid)': '0.066', 'Adrenal cortex cells': '0.681', 'Adrenal medulla cells': '0.153', 'Mitotic cells (Adrenal gland)': '0.200', 'Minor salivary glandular cells': '-0.156', 'Minor salivary gland ductal cells': '-0.153', 'Minor salivary gland basal cells': '0.582', 'Mitotic cells (Minor salivary gland)': '0.397', 'Adipocytes (Minor salivary gland)': '0.229', 'Somatotropes': '-0.069', 'Lactotropes': '0.046', 'Gonadotropes': '0.200', 'Corticotropes': '-0.059', 'Thyrotropes': '0.304', 'Undifferentiated cells (Pituitary gland)': '0.223', 'Mitotic cells (Spleen)': '0.151', 'Platelets': '0.042', 'Erythrocytes': '-0.012', 'Hematopoietic stem cells': '-0.036', 'B-cells (Spleen)': '0.030', 'NK-cells (Spleen)': '-0.023', 'Amygdala excitatory': '32.9', 'Cerebellar inhibitory': '20.8', 'Cge interneuron': '45.3', 'Deep-layer corticothalamic and 6b': '33.3', 'Deep-layer intratelencephalic': '46.3', 'Deep-layer near-projecting': '45.2', 'Eccentric medium spiny neuron': '38.2', 'Hippocampal ca1-3': '38.8', 'Hippocampal ca4': '44.9', 'Hippocampal dentate gyrus': '33.3', 'Lamp5-lhx6 and chandelier': '43.0', 'Lower rhombic lip': '49.4', 'Mammillary body': '17.8', 'Medium spiny neuron': '29.3', 'Mge interneuron': '22.8', 'Midbrain-derived inhibitory': '95.4', 'Miscellaneous': '33.2', 'Splatter': '49.1', 'Thalamic excitatory': '45.7', 'Upper rhombic lip': '24.1', 'Upper-layer intratelencephalic': '23.6', 'Astrocyte': '16.0', 'Bergmann glia': '12.9', 'Central nervous system macrophage': '21.3', 'Choroid plexus epithelial cell': '27.2', 'Committed oligodendrocyte precursor': '69.9', 'Ependymal cell': '74.8', 'Oligodendrocyte': '138.4', 'Oligodendrocyte precursor cell': '51.6', 'Endothelial cell': '18.1', 'Pericyte': '9.5', 'Vascular associated smooth muscle cell': '14.4', 'Fibroblast': '17.9', 'Leukocyte': '20.6', 'Basophil': '5.4', 'Eosinophil': '0.7', 'Neutrophil': '0.4', 'Classical monocyte': '8.5', 'Non-classical monocyte': '11.1', 'Intermediate monocyte': '16.4', 'T-reg': '11.8', 'GdT-cell': '10.6', 'MAIT T-cell': '6.3', 'Memory CD4 T-cell': '6.0', 'Naive CD4 T-cell': '8.0', 'Memory CD8 T-cell': '9.5', 'Naive CD8 T-cell': '6.7', 'Memory B-cell': '16.6', 'Naive B-cell': '37.4', 'Plasmacytoid DC': '17.0', 'Myeloid DC': '24.0', 'NK-cell': '13.2', 'Total PBMC': '13.4', 'Vd2 gdTCR': '8.3', 'Memory CD4 T-cell Th1\\/Th17': '7.0', 'Memory CD4 T-cell Th17': '7.7', 'Memory CD4 T-cell Th2': '8.1', 'Non-Vd2 gdTCR': '18.7', 'Memory CD4 T-cell Th1': '6.3', 'Memory CD4 T-cell TFH': '6.8', 'Terminal effector memory CD4 T-cell': '12.0', 'Central memory CD8 T-cell': '13.2', 'Effector memory CD8 T-cell': '18.5', 'Terminal effector memory CD8 T-cell': '14.6', 'Non-switched memory B-cell': '25.5', 'Plasmablast': '38.2', 'Switched memory B-cell': '29.0', 'Exhausted memory B-cell': '38.1', 'Progenitor cell': '58.4', 'Memory T-reg': '6.6', 'Naive CD4 T-cell activated': '62.5', 'Naive CD8 T-cell activated': '74.6', 'Naive T-reg': '7.5'}
6C6N, 6C6P, 6C6R
{'Adipose Tissue': 11.276246677740865, 'Adrenal Gland': 33.201414728682174, 'Bladder': 11.707333333333334, 'Blood': 18.890652938643704, 'Blood Vessel': 13.284847191011236, 'Brain': 18.775450681302043, 'Breast': 10.531339869281046, 'Cervix Uteri': 31.404631578947367, 'Colon': 11.847207958921697, 'Esophagus': 39.11830795847751, 'Fallopian Tube': 17.005000000000003, 'Heart': 3.912803832752614, 'Kidney': 10.5938202247191, 'Liver': 20.79399513274336, 'Lung': 35.452446366782006, 'Muscle': 0.8250415317559152, 'Nerve': 23.41402423263328, 'Ovary': 24.271255555555555, 'Pancreas': 5.779374390243903, 'Pituitary': 23.83890812720848, 'Prostate': 13.91881224489796, 'Salivary Gland': 23.324561728395064, 'Skin': 60.560567164179105, 'Small Intestine': 16.337550802139038, 'Spleen': 12.753502074688797, 'Stomach': 16.503955431754875, 'Testis': 66.07052631578946, 'Thyroid': 13.62082388973966, 'Uterus': 23.92593661971831, 'Vagina': 67.15085256410256}
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null
null
null
null
DIO2, SQLE
DIO2, SQLE
48
null
UBE2G1
null
null
77.54178
0.474495
86.096672
0.358415
1,342
O60337
Q92813
19651899, E3NethUbiquitome
UbiNet, UbiBrowser, 31181401
MARCHF6
MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '96.0', 'Basal respiratory cells': '52.0', 'Club cells': '60.0', 'Ionocytes': '63.0', 'Mucus glandular cells': '73.0', 'Serous glandular cells': '36.4', 'Gastric mucus-secreting cells': '58.4', 'Proximal enterocytes': '103.8', 'Paneth cells': '59.2', 'Distal enterocytes': '65.1', 'Intestinal goblet cells': '69.6', 'Exocrine glandular cells': '-0.573', 'Basal prostatic cells': '55.8', 'Prostatic glandular cells': '64.5', 'Breast glandular cells': '0.600', 'Breast myoepithelial cells': '0.546', 'Glandular and luminal cells': '78.6', 'Secretory cells': '56.2', 'Basal keratinocytes': '101.2', 'Suprabasal keratinocytes': '87.1', 'Basal squamous epithelial cells': '40.3', 'Squamous epithelial cells': '38.7', 'Alveolar cells type 1': '0.262', 'Alveolar cells type 2': '-0.058', 'Salivary duct cells': '57.4', 'Ductal cells': '0.463', 'Hepatocytes': '0.411', 'Cholangiocytes': '57.2', 'Proximal tubular cells': '0.180', 'Distal tubular cells': '15.4', 'Collecting duct cells': '75.8', 'Mesothelial cells': '0.335', 'Sertoli cells': '0.438', 'Granulosa cells': '55.5', 'Enteroendocrine cells': '64.6', 'Pancreatic endocrine cells': '28.9', 'Leydig cells': '0.533', 'Excitatory neurons': '148.7', 'Inhibitory neurons': '158.9', 'Cone photoreceptor cells': '57.8', 'Rod photoreceptor cells': '78.2', 'Bipolar cells': '92.8', 'Horizontal cells': '100.7', 'Astrocytes': '113.9', 'Oligodendrocyte precursor cells': '132.5', 'Oligodendrocytes': '141.7', 'Microglial cells': '73.4', 'Muller glia cells': '49.8', 'Schwann cells': '0.284', 'Spermatogonia': '0.606', 'Spermatocytes': '0.538', 'Early spermatids': '-0.163', 'Late spermatids': '-0.622', 'Oocytes': '24.3', 'Cytotrophoblasts': '51.7', 'Syncytiotrophoblasts': '83.1', 'Extravillous trophoblasts': '29.9', 'Endothelial cells': '56.4', 'Lymphatic endothelial cells': '48.0', 'Cardiomyocytes': '0.639', 'Skeletal myocytes': '-0.247', 'Smooth muscle cells': '62.3', 'Adipocytes': '57.1', 'Melanocytes': '-0.052', 'Fibroblasts': '58.4', 'Peritubular cells': '0.453', 'Endometrial stromal cells': '54.9', 'Ovarian stromal cells': '59.6', 'Undifferentiated cells': '53.5', 'T-cells': '60.2', 'B-cells': '67.9', 'Plasma cells': '62.1', 'Nk-cells': '59.0', 'Granulocytes': '67.8', 'Monocytes': '84.1', 'Macrophages': '46.1', 'Hofbauer cells': '36.3', 'Kupffer cells': '59.1', 'Dendritic cells': '52.5', 'Langerhans cells': '-0.003', 'Erythroid cells': '0.056', 'Adipocytes (Subcutaneous)': '0.136', 'Adipocytes (Visceral)': '-0.155', 'Breast glandular cells (progenitors)': '0.406', 'Adipocytes (Breast)': '-0.500', 'Colon enterocytes': '0.058', 'Colon enteroendocrine cells': '0.264', 'Enteric glia cells': '0.112', 'Mitotic cells (Colon)': '0.116', 'Mitotic cells (Heart)': '0.464', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.412', 'Intercalated cells': '-0.089', 'Cholangiocyte': '0.287', 'NK-cells (Liver)': '-0.215', 'Respiratory ciliated cells': '0.173', 'Mitotic cells (Lung)': '-0.162', 'NK-cells (Lung)': '0.254', 'B-cells (Lung)': '0.166', 'Alpha cells': '0.359', 'Beta cells': '0.223', 'Prostate glandular cells': '-0.043', 'Prostate basal glandular cells': '0.321', 'Urothelial cells': '0.224', 'Keratinocyte (other)': '-0.062', 'Keratinocyte (granular)': '-0.047', 'Hair cortex cells': '-0.087', 'Inner root sheath cells': '-0.055', 'Outer root sheath cells': '0.031', 'Sebaceous gland cells': '-0.014', 'Eccrine sweat gland cells': '0.022', 'Adipocytes (Skin)': '0.070', 'Mitotic cells (Skin)': '-0.001', 'Parietal cells': '0.002', 'Chief cells': '-0.047', 'Gastric mucous cells': '0.235', 'Gastric enteroendocrine cells': '0.064', 'Mitotic cells (Stomach)': '0.157', 'Parafollicular cells': '0.069', 'Thyroid glandular cells': '0.406', 'Mitotic cells (Thyroid)': '-0.033', 'Adrenal cortex cells': '0.529', 'Adrenal medulla cells': '0.161', 'Mitotic cells (Adrenal gland)': '0.238', 'Minor salivary glandular cells': '0.634', 'Minor salivary gland ductal cells': '0.327', 'Minor salivary gland basal cells': '0.051', 'Mitotic cells (Minor salivary gland)': '0.025', 'Adipocytes (Minor salivary gland)': '0.093', 'Somatotropes': '-0.142', 'Lactotropes': '-0.039', 'Gonadotropes': '0.109', 'Corticotropes': '-0.097', 'Thyrotropes': '0.091', 'Undifferentiated cells (Pituitary gland)': '0.279', 'Mitotic cells (Spleen)': '-0.204', 'Platelets': '-0.089', 'Erythrocytes': '-0.132', 'Hematopoietic stem cells': '-0.196', 'B-cells (Spleen)': '0.425', 'NK-cells (Spleen)': '0.278', 'Amygdala excitatory': '192.6', 'Cerebellar inhibitory': '215.3', 'Cge interneuron': '263.0', 'Deep-layer corticothalamic and 6b': '200.6', 'Deep-layer intratelencephalic': '197.0', 'Deep-layer near-projecting': '209.5', 'Eccentric medium spiny neuron': '222.1', 'Hippocampal ca1-3': '209.0', 'Hippocampal ca4': '169.4', 'Hippocampal dentate gyrus': '211.4', 'Lamp5-lhx6 and chandelier': '238.8', 'Lower rhombic lip': '177.0', 'Mammillary body': '191.3', 'Medium spiny neuron': '180.7', 'Mge interneuron': '213.3', 'Midbrain-derived inhibitory': '207.1', 'Miscellaneous': '208.1', 'Splatter': '198.1', 'Thalamic excitatory': '199.0', 'Upper rhombic lip': '221.2', 'Upper-layer intratelencephalic': '211.3', 'Astrocyte': '231.4', 'Bergmann glia': '165.8', 'Central nervous system macrophage': '196.0', 'Choroid plexus epithelial cell': '160.2', 'Committed oligodendrocyte precursor': '150.5', 'Ependymal cell': '357.9', 'Oligodendrocyte': '230.6', 'Oligodendrocyte precursor cell': '197.8', 'Endothelial cell': '245.6', 'Pericyte': '186.9', 'Vascular associated smooth muscle cell': '193.1', 'Fibroblast': '219.2', 'Leukocyte': '230.5', 'Basophil': '108.6', 'Eosinophil': '12.6', 'Neutrophil': '123.2', 'Classical monocyte': '69.4', 'Non-classical monocyte': '100.2', 'Intermediate monocyte': '58.9', 'T-reg': '83.5', 'GdT-cell': '11.2', 'MAIT T-cell': '89.9', 'Memory CD4 T-cell': '10.8', 'Naive CD4 T-cell': '181.5', 'Memory CD8 T-cell': '11.0', 'Naive CD8 T-cell': '172.1', 'Memory B-cell': '11.7', 'Naive B-cell': '169.6', 'Plasmacytoid DC': '39.4', 'Myeloid DC': '56.9', 'NK-cell': '112.5', 'Total PBMC': '60.1', 'Vd2 gdTCR': '78.2', 'Memory CD4 T-cell Th1\\/Th17': '171.5', 'Memory CD4 T-cell Th17': '154.0', 'Memory CD4 T-cell Th2': '170.0', 'Non-Vd2 gdTCR': '93.3', 'Memory CD4 T-cell Th1': '146.3', 'Memory CD4 T-cell TFH': '137.9', 'Terminal effector memory CD4 T-cell': '88.0', 'Central memory CD8 T-cell': '87.5', 'Effector memory CD8 T-cell': '84.2', 'Terminal effector memory CD8 T-cell': '79.9', 'Non-switched memory B-cell': '81.3', 'Plasmablast': '112.1', 'Switched memory B-cell': '79.4', 'Exhausted memory B-cell': '75.4', 'Progenitor cell': '95.1', 'Memory T-reg': '138.0', 'Naive CD4 T-cell activated': '119.2', 'Naive CD8 T-cell activated': '110.0', 'Naive T-reg': '199.9'}
null
{'Adipose Tissue': 36.31873754152824, 'Adrenal Gland': 25.83708914728682, 'Bladder': 37.19904761904762, 'Blood': 21.980406889128098, 'Blood Vessel': 41.85550561797753, 'Brain': 29.084541635124904, 'Breast': 42.736405228758166, 'Cervix Uteri': 48.53578947368421, 'Colon': 33.41946598202824, 'Esophagus': 28.81244567474048, 'Fallopian Tube': 59.346666666666664, 'Heart': 15.93619512195122, 'Kidney': 20.683662921348315, 'Liver': 14.074880530973452, 'Lung': 49.03328719723184, 'Muscle': 34.10750435865504, 'Nerve': 53.29239095315024, 'Ovary': 65.94533333333334, 'Pancreas': 23.688786585365857, 'Pituitary': 42.42575971731448, 'Prostate': 36.94277551020408, 'Salivary Gland': 36.87234567901234, 'Skin': 41.76371475953565, 'Small Intestine': 48.07802139037433, 'Spleen': 39.45315352697095, 'Stomach': 31.6258495821727, 'Testis': 30.937534626038783, 'Thyroid': 54.50356814701379, 'Uterus': 57.17781690140845, 'Vagina': 39.84307692307693}
DIO2
MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGLRCVWKSFLLDAYKQVKLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSKRUKKTRLAG
Homo sapiens
Membrane
Tissue enhanced (cervix, thyroid gland)
{'Ciliated cells': '3.2', 'Basal respiratory cells': '0.1', 'Club cells': '0.1', 'Ionocytes': '0.0', 'Mucus glandular cells': '10.7', 'Serous glandular cells': '13.4', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.1', 'Exocrine glandular cells': '-0.205', 'Basal prostatic cells': '2.9', 'Prostatic glandular cells': '0.3', 'Breast glandular cells': '0.350', 'Breast myoepithelial cells': '0.545', 'Glandular and luminal cells': '12.9', 'Secretory cells': '0.4', 'Basal keratinocytes': '12.9', 'Suprabasal keratinocytes': '15.0', 'Basal squamous epithelial cells': '2.2', 'Squamous epithelial cells': '11.2', 'Alveolar cells type 1': '-0.191', 'Alveolar cells type 2': '-0.310', 'Salivary duct cells': '1.7', 'Ductal cells': '0.321', 'Hepatocytes': '0.034', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.058', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '-0.164', 'Sertoli cells': '-0.614', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.548', 'Excitatory neurons': '0.9', 'Inhibitory neurons': '0.9', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '3.4', 'Bipolar cells': '6.3', 'Horizontal cells': '6.3', 'Astrocytes': '50.2', 'Oligodendrocyte precursor cells': '8.0', 'Oligodendrocytes': '1.3', 'Microglial cells': '4.5', 'Muller glia cells': '191.4', 'Schwann cells': '-0.047', 'Spermatogonia': '-0.417', 'Spermatocytes': '-0.006', 'Early spermatids': '0.792', 'Late spermatids': '0.614', 'Oocytes': '0.0', 'Cytotrophoblasts': '8.2', 'Syncytiotrophoblasts': '26.0', 'Extravillous trophoblasts': '586.4', 'Endothelial cells': '2.7', 'Lymphatic endothelial cells': '0.7', 'Cardiomyocytes': '0.013', 'Skeletal myocytes': '0.069', 'Smooth muscle cells': '23.0', 'Adipocytes': '0.6', 'Melanocytes': '0.096', 'Fibroblasts': '36.0', 'Peritubular cells': '-0.367', 'Endometrial stromal cells': '141.7', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '0.0', 'T-cells': '1.7', 'B-cells': '0.4', 'Plasma cells': '1.9', 'Nk-cells': '0.0', 'Granulocytes': '4.7', 'Monocytes': '0.2', 'Macrophages': '1.9', 'Hofbauer cells': '4.4', 'Kupffer cells': '1.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.059', 'Erythroid cells': '0.036', 'Adipocytes (Subcutaneous)': '-0.483', 'Adipocytes (Visceral)': '0.036', 'Breast glandular cells (progenitors)': '0.269', 'Adipocytes (Breast)': '-0.412', 'Colon enterocytes': '0.153', 'Colon enteroendocrine cells': '0.037', 'Enteric glia cells': '0.278', 'Mitotic cells (Colon)': '0.288', 'Mitotic cells (Heart)': '0.208', 'Podocytes': '0.069', 'Ascending Loop of Henle cells': '0.401', 'Intercalated cells': '0.252', 'Cholangiocyte': '0.234', 'NK-cells (Liver)': '0.010', 'Respiratory ciliated cells': '0.297', 'Mitotic cells (Lung)': '0.057', 'NK-cells (Lung)': '0.108', 'B-cells (Lung)': '0.274', 'Alpha cells': '0.159', 'Beta cells': '0.051', 'Prostate glandular cells': '0.065', 'Prostate basal glandular cells': '0.077', 'Urothelial cells': '0.153', 'Keratinocyte (other)': '-0.377', 'Keratinocyte (granular)': '-0.209', 'Hair cortex cells': '0.338', 'Inner root sheath cells': '0.393', 'Outer root sheath cells': '0.529', 'Sebaceous gland cells': '0.248', 'Eccrine sweat gland cells': '0.238', 'Adipocytes (Skin)': '0.220', 'Mitotic cells (Skin)': '0.105', 'Parietal cells': '0.306', 'Chief cells': '0.275', 'Gastric mucous cells': '0.454', 'Gastric enteroendocrine cells': '0.417', 'Mitotic cells (Stomach)': '0.224', 'Parafollicular cells': '0.137', 'Thyroid glandular cells': '0.474', 'Mitotic cells (Thyroid)': '0.072', 'Adrenal cortex cells': '0.528', 'Adrenal medulla cells': '0.029', 'Mitotic cells (Adrenal gland)': '-0.112', 'Minor salivary glandular cells': '-0.065', 'Minor salivary gland ductal cells': '-0.257', 'Minor salivary gland basal cells': '0.646', 'Mitotic cells (Minor salivary gland)': '0.715', 'Adipocytes (Minor salivary gland)': '0.105', 'Somatotropes': '-0.221', 'Lactotropes': '0.180', 'Gonadotropes': '0.090', 'Corticotropes': '0.271', 'Thyrotropes': '0.812', 'Undifferentiated cells (Pituitary gland)': '0.107', 'Mitotic cells (Spleen)': '0.113', 'Platelets': '0.143', 'Erythrocytes': '0.180', 'Hematopoietic stem cells': '0.052', 'B-cells (Spleen)': '-0.085', 'NK-cells (Spleen)': '0.091', 'Amygdala excitatory': '25.3', 'Cerebellar inhibitory': '6.9', 'Cge interneuron': '8.3', 'Deep-layer corticothalamic and 6b': '24.5', 'Deep-layer intratelencephalic': '15.1', 'Deep-layer near-projecting': '13.8', 'Eccentric medium spiny neuron': '26.8', 'Hippocampal ca1-3': '19.1', 'Hippocampal ca4': '9.0', 'Hippocampal dentate gyrus': '35.9', 'Lamp5-lhx6 and chandelier': '7.7', 'Lower rhombic lip': '6.6', 'Mammillary body': '5.3', 'Medium spiny neuron': '53.5', 'Mge interneuron': '6.2', 'Midbrain-derived inhibitory': '16.1', 'Miscellaneous': '11.6', 'Splatter': '8.9', 'Thalamic excitatory': '6.2', 'Upper rhombic lip': '6.5', 'Upper-layer intratelencephalic': '13.7', 'Astrocyte': '64.3', 'Bergmann glia': '5.4', 'Central nervous system macrophage': '6.0', 'Choroid plexus epithelial cell': '16.8', 'Committed oligodendrocyte precursor': '58.5', 'Ependymal cell': '31.3', 'Oligodendrocyte': '9.5', 'Oligodendrocyte precursor cell': '19.6', 'Endothelial cell': '1.9', 'Pericyte': '1.4', 'Vascular associated smooth muscle cell': '27.7', 'Fibroblast': '9.8', 'Leukocyte': '0.7', 'Basophil': '0.1', 'Eosinophil': '0.0', 'Neutrophil': '0.4', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.1', 'T-reg': '0.1', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.4', 'Myeloid DC': '0.1', 'NK-cell': '0.0', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.7', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.5', 'Memory T-reg': '0.1', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
null
{'Adipose Tissue': 1.5754392524916945, 'Adrenal Gland': 2.6333387596899223, 'Bladder': 2.3652366666666667, 'Blood': 0.0384701420882669, 'Blood Vessel': 4.490663715355805, 'Brain': 10.151482702498107, 'Breast': 3.070856753812636, 'Cervix Uteri': 46.16224210526316, 'Colon': 0.7489406033376123, 'Esophagus': 32.07648588235294, 'Fallopian Tube': 0.8291555555555555, 'Heart': 2.368808675958188, 'Kidney': 0.9601640449438202, 'Liver': 0.0556760398230088, 'Lung': 1.199763858131488, 'Muscle': 4.032821295143213, 'Nerve': 3.422191760904685, 'Ovary': 0.3902503333333333, 'Pancreas': 0.43093375, 'Pituitary': 50.156014134275615, 'Prostate': 15.328240816326533, 'Salivary Gland': 42.47758641975309, 'Skin': 6.096332780541736, 'Small Intestine': 1.133567165775401, 'Spleen': 0.3004109958506224, 'Stomach': 2.8063607242339836, 'Testis': 4.850887257617728, 'Thyroid': 108.24497702909648, 'Uterus': 2.825891408450704, 'Vagina': 38.54897051282051}
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null
null
null
null
null
null
DIO2, SQLE
DIO2, SQLE
48
null
UBE2G1
null
null
77.54178
0.474495
null
null
2,475
O60683
P50542
22199232, hUbiquitome
UbiNet, UbiBrowser, 31181401
PEX10
MAPAAASPPEVIRAAQKDEYYRGGLRSAAGGALHSLAGARKWLEWRKEVELLSDVAYFGLTTLAGYQTLGEEYVSIIQVDPSRIHVPSSLRRGVLVTLHAVLPYLLDKALLPLEQELQADPDSGRPLQGSLGPGGRGCSGARRWMRHHTATLTEQQRRALLRAVFVLRQGLACLQRLHVAWFYIHGVFYHLAKRLTGITYLRVRSLPGEDLRARVSYRLLGVISLLHLVLSMGLQLYGFRQRQRARKEWRLHRGLSHRRASLEERAVSRNPLCTLCLEERRHPTATPCGHLFCWECITAWCSSKAECPLCREKFPPQKLIYLRHYR
Homo sapiens
Peroxisome membrane
Low tissue specificity
{'Ciliated cells': '11.1', 'Basal respiratory cells': '15.7', 'Club cells': '14.9', 'Ionocytes': '11.8', 'Mucus glandular cells': '8.7', 'Serous glandular cells': '7.9', 'Gastric mucus-secreting cells': '13.0', 'Proximal enterocytes': '17.1', 'Paneth cells': '15.7', 'Distal enterocytes': '10.5', 'Intestinal goblet cells': '10.1', 'Exocrine glandular cells': '-0.681', 'Basal prostatic cells': '9.0', 'Prostatic glandular cells': '14.0', 'Breast glandular cells': '0.143', 'Breast myoepithelial cells': '0.069', 'Glandular and luminal cells': '11.4', 'Secretory cells': '20.7', 'Basal keratinocytes': '10.9', 'Suprabasal keratinocytes': '13.7', 'Basal squamous epithelial cells': '14.6', 'Squamous epithelial cells': '23.7', 'Alveolar cells type 1': '-0.035', 'Alveolar cells type 2': '0.212', 'Salivary duct cells': '8.1', 'Ductal cells': '0.488', 'Hepatocytes': '0.445', 'Cholangiocytes': '13.4', 'Proximal tubular cells': '0.170', 'Distal tubular cells': '52.2', 'Collecting duct cells': '15.6', 'Mesothelial cells': '0.132', 'Sertoli cells': '-0.312', 'Granulosa cells': '22.9', 'Enteroendocrine cells': '11.2', 'Pancreatic endocrine cells': '13.6', 'Leydig cells': '-0.448', 'Excitatory neurons': '4.9', 'Inhibitory neurons': '5.4', 'Cone photoreceptor cells': '20.4', 'Rod photoreceptor cells': '10.5', 'Bipolar cells': '14.1', 'Horizontal cells': '10.7', 'Astrocytes': '3.1', 'Oligodendrocyte precursor cells': '7.5', 'Oligodendrocytes': '6.3', 'Microglial cells': '2.7', 'Muller glia cells': '43.0', 'Schwann cells': '0.023', 'Spermatogonia': '-0.131', 'Spermatocytes': '0.264', 'Early spermatids': '0.580', 'Late spermatids': '0.566', 'Oocytes': '10.3', 'Cytotrophoblasts': '27.1', 'Syncytiotrophoblasts': '26.3', 'Extravillous trophoblasts': '25.3', 'Endothelial cells': '10.9', 'Lymphatic endothelial cells': '17.6', 'Cardiomyocytes': '0.699', 'Skeletal myocytes': '0.263', 'Smooth muscle cells': '11.7', 'Adipocytes': '12.2', 'Melanocytes': '0.218', 'Fibroblasts': '11.5', 'Peritubular cells': '-0.303', 'Endometrial stromal cells': '8.9', 'Ovarian stromal cells': '19.9', 'Undifferentiated cells': '21.2', 'T-cells': '5.9', 'B-cells': '11.3', 'Plasma cells': '13.1', 'Nk-cells': '4.5', 'Granulocytes': '10.5', 'Monocytes': '5.9', 'Macrophages': '9.3', 'Hofbauer cells': '19.1', 'Kupffer cells': '7.3', 'Dendritic cells': '7.4', 'Langerhans cells': '0.303', 'Erythroid cells': '-0.059', 'Adipocytes (Subcutaneous)': '0.485', 'Adipocytes (Visceral)': '0.496', 'Breast glandular cells (progenitors)': '0.046', 'Adipocytes (Breast)': '0.143', 'Colon enterocytes': '-0.107', 'Colon enteroendocrine cells': '0.253', 'Enteric glia cells': '0.149', 'Mitotic cells (Colon)': '-0.085', 'Mitotic cells (Heart)': '0.538', 'Podocytes': '-0.032', 'Ascending Loop of Henle cells': '0.495', 'Intercalated cells': '0.093', 'Cholangiocyte': '0.009', 'NK-cells (Liver)': '0.104', 'Respiratory ciliated cells': '0.042', 'Mitotic cells (Lung)': '0.242', 'NK-cells (Lung)': '-0.176', 'B-cells (Lung)': '-0.217', 'Alpha cells': '0.345', 'Beta cells': '0.186', 'Prostate glandular cells': '0.423', 'Prostate basal glandular cells': '0.342', 'Urothelial cells': '0.187', 'Keratinocyte (other)': '0.113', 'Keratinocyte (granular)': '-0.090', 'Hair cortex cells': '0.228', 'Inner root sheath cells': '0.248', 'Outer root sheath cells': '0.376', 'Sebaceous gland cells': '0.268', 'Eccrine sweat gland cells': '0.101', 'Adipocytes (Skin)': '0.033', 'Mitotic cells (Skin)': '0.392', 'Parietal cells': '-0.480', 'Chief cells': '-0.276', 'Gastric mucous cells': '-0.275', 'Gastric enteroendocrine cells': '-0.234', 'Mitotic cells (Stomach)': '0.112', 'Parafollicular cells': '0.150', 'Thyroid glandular cells': '0.575', 'Mitotic cells (Thyroid)': '-0.058', 'Adrenal cortex cells': '0.557', 'Adrenal medulla cells': '0.003', 'Mitotic cells (Adrenal gland)': '0.419', 'Minor salivary glandular cells': '0.448', 'Minor salivary gland ductal cells': '0.018', 'Minor salivary gland basal cells': '0.265', 'Mitotic cells (Minor salivary gland)': '0.299', 'Adipocytes (Minor salivary gland)': '0.088', 'Somatotropes': '-0.130', 'Lactotropes': '0.027', 'Gonadotropes': '0.262', 'Corticotropes': '-0.092', 'Thyrotropes': '0.140', 'Undifferentiated cells (Pituitary gland)': '0.356', 'Mitotic cells (Spleen)': '-0.255', 'Platelets': '-0.130', 'Erythrocytes': '-0.119', 'Hematopoietic stem cells': '-0.243', 'B-cells (Spleen)': '0.213', 'NK-cells (Spleen)': '0.159', 'Amygdala excitatory': '8.2', 'Cerebellar inhibitory': '10.5', 'Cge interneuron': '11.0', 'Deep-layer corticothalamic and 6b': '9.5', 'Deep-layer intratelencephalic': '10.9', 'Deep-layer near-projecting': '12.1', 'Eccentric medium spiny neuron': '7.8', 'Hippocampal ca1-3': '9.8', 'Hippocampal ca4': '10.9', 'Hippocampal dentate gyrus': '10.2', 'Lamp5-lhx6 and chandelier': '13.0', 'Lower rhombic lip': '13.4', 'Mammillary body': '9.0', 'Medium spiny neuron': '8.7', 'Mge interneuron': '12.1', 'Midbrain-derived inhibitory': '8.6', 'Miscellaneous': '10.1', 'Splatter': '10.4', 'Thalamic excitatory': '11.8', 'Upper rhombic lip': '5.8', 'Upper-layer intratelencephalic': '9.6', 'Astrocyte': '9.8', 'Bergmann glia': '19.8', 'Central nervous system macrophage': '8.7', 'Choroid plexus epithelial cell': '11.2', 'Committed oligodendrocyte precursor': '13.9', 'Ependymal cell': '14.2', 'Oligodendrocyte': '15.0', 'Oligodendrocyte precursor cell': '14.1', 'Endothelial cell': '7.8', 'Pericyte': '12.0', 'Vascular associated smooth muscle cell': '8.9', 'Fibroblast': '8.6', 'Leukocyte': '6.5', 'Basophil': '7.6', 'Eosinophil': '1.7', 'Neutrophil': '2.6', 'Classical monocyte': '2.7', 'Non-classical monocyte': '3.0', 'Intermediate monocyte': '21.4', 'T-reg': '10.8', 'GdT-cell': '3.8', 'MAIT T-cell': '13.4', 'Memory CD4 T-cell': '3.3', 'Naive CD4 T-cell': '2.7', 'Memory CD8 T-cell': '5.1', 'Naive CD8 T-cell': '3.2', 'Memory B-cell': '6.0', 'Naive B-cell': '3.0', 'Plasmacytoid DC': '21.5', 'Myeloid DC': '15.3', 'NK-cell': '3.1', 'Total PBMC': '11.3', 'Vd2 gdTCR': '13.1', 'Memory CD4 T-cell Th1\\/Th17': '2.4', 'Memory CD4 T-cell Th17': '3.1', 'Memory CD4 T-cell Th2': '3.0', 'Non-Vd2 gdTCR': '10.3', 'Memory CD4 T-cell Th1': '3.5', 'Memory CD4 T-cell TFH': '4.3', 'Terminal effector memory CD4 T-cell': '9.9', 'Central memory CD8 T-cell': '7.8', 'Effector memory CD8 T-cell': '8.7', 'Terminal effector memory CD8 T-cell': '7.2', 'Non-switched memory B-cell': '15.4', 'Plasmablast': '16.8', 'Switched memory B-cell': '15.3', 'Exhausted memory B-cell': '10.9', 'Progenitor cell': '24.1', 'Memory T-reg': '3.5', 'Naive CD4 T-cell activated': '5.2', 'Naive CD8 T-cell activated': '6.5', 'Naive T-reg': '3.0'}
null
{'Adipose Tissue': 14.55998504983389, 'Adrenal Gland': 22.86222480620155, 'Bladder': 14.385095238095236, 'Blood': 4.737086006458558, 'Blood Vessel': 12.40587191011236, 'Brain': 14.979331945495836, 'Breast': 15.0349825708061, 'Cervix Uteri': 13.90484210526316, 'Colon': 10.396145057766368, 'Esophagus': 12.137662283737024, 'Fallopian Tube': 13.527888888888889, 'Heart': 5.905779674796748, 'Kidney': 10.256831460674157, 'Liver': 6.896030973451327, 'Lung': 10.521391003460208, 'Muscle': 8.865173100871731, 'Nerve': 21.199709208400648, 'Ovary': 15.987455555555556, 'Pancreas': 7.405914634146341, 'Pituitary': 18.50519787985866, 'Prostate': 16.7386, 'Salivary Gland': 13.367024691358026, 'Skin': 15.627780541735763, 'Small Intestine': 9.008240641711229, 'Spleen': 9.505414937759337, 'Stomach': 9.1603286908078, 'Testis': 33.457626038781164, 'Thyroid': 16.545807044410413, 'Uterus': 14.344450704225352, 'Vagina': 13.364846153846155}
PEX5
MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTATDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Homo sapiens
Cytoplasm, cytosol, Peroxisome matrix
Low tissue specificity
{'Ciliated cells': '6.3', 'Basal respiratory cells': '4.0', 'Club cells': '4.2', 'Ionocytes': '4.0', 'Mucus glandular cells': '7.7', 'Serous glandular cells': '5.2', 'Gastric mucus-secreting cells': '4.1', 'Proximal enterocytes': '10.6', 'Paneth cells': '11.4', 'Distal enterocytes': '8.2', 'Intestinal goblet cells': '8.5', 'Exocrine glandular cells': '-0.629', 'Basal prostatic cells': '7.6', 'Prostatic glandular cells': '7.2', 'Breast glandular cells': '-0.050', 'Breast myoepithelial cells': '-0.260', 'Glandular and luminal cells': '5.1', 'Secretory cells': '5.2', 'Basal keratinocytes': '11.8', 'Suprabasal keratinocytes': '10.0', 'Basal squamous epithelial cells': '8.2', 'Squamous epithelial cells': '6.7', 'Alveolar cells type 1': '0.197', 'Alveolar cells type 2': '0.158', 'Salivary duct cells': '6.0', 'Ductal cells': '0.443', 'Hepatocytes': '0.426', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.421', 'Distal tubular cells': '3.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '-0.104', 'Sertoli cells': '0.183', 'Granulosa cells': '7.4', 'Enteroendocrine cells': '15.7', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '-0.070', 'Excitatory neurons': '30.4', 'Inhibitory neurons': '21.2', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '7.6', 'Bipolar cells': '8.1', 'Horizontal cells': '5.7', 'Astrocytes': '10.8', 'Oligodendrocyte precursor cells': '15.1', 'Oligodendrocytes': '12.3', 'Microglial cells': '0.9', 'Muller glia cells': '11.0', 'Schwann cells': '0.096', 'Spermatogonia': '0.284', 'Spermatocytes': '0.361', 'Early spermatids': '0.186', 'Late spermatids': '0.179', 'Oocytes': '14.7', 'Cytotrophoblasts': '11.0', 'Syncytiotrophoblasts': '6.9', 'Extravillous trophoblasts': '5.9', 'Endothelial cells': '9.4', 'Lymphatic endothelial cells': '8.7', 'Cardiomyocytes': '0.586', 'Skeletal myocytes': '-0.315', 'Smooth muscle cells': '8.8', 'Adipocytes': '8.5', 'Melanocytes': '-0.094', 'Fibroblasts': '7.5', 'Peritubular cells': '0.003', 'Endometrial stromal cells': '12.5', 'Ovarian stromal cells': '8.6', 'Undifferentiated cells': '11.9', 'T-cells': '5.3', 'B-cells': '5.0', 'Plasma cells': '3.7', 'Nk-cells': '4.4', 'Granulocytes': '4.4', 'Monocytes': '3.5', 'Macrophages': '4.6', 'Hofbauer cells': '4.7', 'Kupffer cells': '7.1', 'Dendritic cells': '13.7', 'Langerhans cells': '0.205', 'Erythroid cells': '-0.163', 'Adipocytes (Subcutaneous)': '0.506', 'Adipocytes (Visceral)': '0.571', 'Breast glandular cells (progenitors)': '-0.041', 'Adipocytes (Breast)': '0.497', 'Colon enterocytes': '-0.156', 'Colon enteroendocrine cells': '0.135', 'Enteric glia cells': '-0.135', 'Mitotic cells (Colon)': '-0.095', 'Mitotic cells (Heart)': '0.463', 'Podocytes': '-0.091', 'Ascending Loop of Henle cells': '0.290', 'Intercalated cells': '0.009', 'Cholangiocyte': '0.073', 'NK-cells (Liver)': '-0.308', 'Respiratory ciliated cells': '-0.070', 'Mitotic cells (Lung)': '-0.185', 'NK-cells (Lung)': '0.045', 'B-cells (Lung)': '-0.103', 'Alpha cells': '0.331', 'Beta cells': '0.216', 'Prostate glandular cells': '-0.336', 'Prostate basal glandular cells': '0.093', 'Urothelial cells': '0.201', 'Keratinocyte (other)': '-0.002', 'Keratinocyte (granular)': '0.159', 'Hair cortex cells': '-0.078', 'Inner root sheath cells': '-0.035', 'Outer root sheath cells': '-0.101', 'Sebaceous gland cells': '0.127', 'Eccrine sweat gland cells': '-0.072', 'Adipocytes (Skin)': '0.161', 'Mitotic cells (Skin)': '-0.066', 'Parietal cells': '-0.678', 'Chief cells': '-0.552', 'Gastric mucous cells': '-0.461', 'Gastric enteroendocrine cells': '-0.445', 'Mitotic cells (Stomach)': '-0.029', 'Parafollicular cells': '0.047', 'Thyroid glandular cells': '0.304', 'Mitotic cells (Thyroid)': '-0.062', 'Adrenal cortex cells': '0.330', 'Adrenal medulla cells': '0.155', 'Mitotic cells (Adrenal gland)': '0.196', 'Minor salivary glandular cells': '0.647', 'Minor salivary gland ductal cells': '0.138', 'Minor salivary gland basal cells': '0.137', 'Mitotic cells (Minor salivary gland)': '0.216', 'Adipocytes (Minor salivary gland)': '0.420', 'Somatotropes': '0.074', 'Lactotropes': '0.131', 'Gonadotropes': '0.016', 'Corticotropes': '-0.183', 'Thyrotropes': '-0.140', 'Undifferentiated cells (Pituitary gland)': '0.067', 'Mitotic cells (Spleen)': '-0.364', 'Platelets': '-0.152', 'Erythrocytes': '-0.159', 'Hematopoietic stem cells': '-0.298', 'B-cells (Spleen)': '0.409', 'NK-cells (Spleen)': '0.219', 'Amygdala excitatory': '42.6', 'Cerebellar inhibitory': '25.0', 'Cge interneuron': '23.7', 'Deep-layer corticothalamic and 6b': '33.3', 'Deep-layer intratelencephalic': '37.2', 'Deep-layer near-projecting': '35.5', 'Eccentric medium spiny neuron': '29.9', 'Hippocampal ca1-3': '45.7', 'Hippocampal ca4': '30.3', 'Hippocampal dentate gyrus': '35.5', 'Lamp5-lhx6 and chandelier': '24.2', 'Lower rhombic lip': '30.7', 'Mammillary body': '30.7', 'Medium spiny neuron': '43.0', 'Mge interneuron': '31.8', 'Midbrain-derived inhibitory': '17.5', 'Miscellaneous': '37.3', 'Splatter': '27.9', 'Thalamic excitatory': '36.1', 'Upper rhombic lip': '28.1', 'Upper-layer intratelencephalic': '44.3', 'Astrocyte': '16.0', 'Bergmann glia': '13.8', 'Central nervous system macrophage': '12.9', 'Choroid plexus epithelial cell': '18.0', 'Committed oligodendrocyte precursor': '18.9', 'Ependymal cell': '28.1', 'Oligodendrocyte': '17.4', 'Oligodendrocyte precursor cell': '22.7', 'Endothelial cell': '11.0', 'Pericyte': '14.4', 'Vascular associated smooth muscle cell': '20.1', 'Fibroblast': '13.7', 'Leukocyte': '10.6', 'Basophil': '7.1', 'Eosinophil': '2.1', 'Neutrophil': '5.0', 'Classical monocyte': '10.1', 'Non-classical monocyte': '17.7', 'Intermediate monocyte': '9.3', 'T-reg': '16.6', 'GdT-cell': '2.9', 'MAIT T-cell': '12.7', 'Memory CD4 T-cell': '2.1', 'Naive CD4 T-cell': '27.9', 'Memory CD8 T-cell': '2.9', 'Naive CD8 T-cell': '27.3', 'Memory B-cell': '2.0', 'Naive B-cell': '15.7', 'Plasmacytoid DC': '34.6', 'Myeloid DC': '10.5', 'NK-cell': '24.2', 'Total PBMC': '12.6', 'Vd2 gdTCR': '13.1', 'Memory CD4 T-cell Th1\\/Th17': '20.1', 'Memory CD4 T-cell Th17': '20.9', 'Memory CD4 T-cell Th2': '20.4', 'Non-Vd2 gdTCR': '15.6', 'Memory CD4 T-cell Th1': '22.7', 'Memory CD4 T-cell TFH': '24.9', 'Terminal effector memory CD4 T-cell': '16.5', 'Central memory CD8 T-cell': '13.7', 'Effector memory CD8 T-cell': '13.0', 'Terminal effector memory CD8 T-cell': '17.5', 'Non-switched memory B-cell': '12.1', 'Plasmablast': '10.2', 'Switched memory B-cell': '18.2', 'Exhausted memory B-cell': '16.7', 'Progenitor cell': '22.8', 'Memory T-reg': '20.6', 'Naive CD4 T-cell activated': '116.1', 'Naive CD8 T-cell activated': '111.9', 'Naive T-reg': '29.4'}
1FCH, 2C0L, 2C0M, 2J9Q, 2W84, 3R9A, 4BXU, 4KXK, 4KYO, 7Z0K
{'Adipose Tissue': 36.38524252491695, 'Adrenal Gland': 25.29748449612403, 'Bladder': 27.124285714285715, 'Blood': 7.09388439181916, 'Blood Vessel': 31.032359550561797, 'Brain': 31.792554504163515, 'Breast': 39.46154684095861, 'Cervix Uteri': 37.81894736842105, 'Colon': 25.668591784338897, 'Esophagus': 23.971244982698963, 'Fallopian Tube': 33.90777777777778, 'Heart': 10.359298838559814, 'Kidney': 17.300730337078654, 'Liver': 17.88657522123894, 'Lung': 29.322456747404846, 'Muscle': 37.88648816936488, 'Nerve': 44.18266558966074, 'Ovary': 40.10961111111111, 'Pancreas': 13.585530487804878, 'Pituitary': 52.665618374558306, 'Prostate': 25.807044897959184, 'Salivary Gland': 22.682549382716047, 'Skin': 28.29241680486457, 'Small Intestine': 21.745743315508022, 'Spleen': 18.18073029045643, 'Stomach': 19.98205849582173, 'Testis': 77.25722991689751, 'Thyroid': 29.47088514548239, 'Uterus': 38.14415492957747, 'Vagina': 28.268525641025644}
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RING finger
Component of the PEX2-PEX10-PEX12 retrotranslocation channel,
PEX
null
PEX19, PEX2,PEX12
PEX5
null
null
null
null
null
82.660031
0.43862
70.862191
0.476322
1,150
O60784
Q15742
22199232, E3Net
UbiNet, UbiBrowser, 31181401
TOM1
MDFLLGNPFSSPVGQRIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVTIYEDLRRKGLEFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQQEDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQAEPADLELLQELNRTCRAMQQRVLELIPQIANEQLTEELLIVNDNLNNVFLRHERFERFRTGQTTKAPSEAEPAADLIDMGPDPAATGNLSSQLAGMNLGSSSVRAGLQSLEASGRLEDEFDMFALTRGSSLADQRKEVKYEAPQATDGLAGALDARQQSTGAIPVTQACLMEDIEQWLSTDVGNDAEEPKGVTSEEFDKFLEERAKAADRLPNLSSPSAEGPPGPPSGPAPRKKTQEKDDDMLFAL
Homo sapiens
Cytoplasm, Endosome membrane, Early endosome membrane
Tissue enhanced (skeletal)
{'Ciliated cells': '24.4', 'Basal respiratory cells': '28.0', 'Club cells': '23.0', 'Ionocytes': '54.9', 'Mucus glandular cells': '41.5', 'Serous glandular cells': '17.6', 'Gastric mucus-secreting cells': '14.7', 'Proximal enterocytes': '52.9', 'Paneth cells': '16.8', 'Distal enterocytes': '39.0', 'Intestinal goblet cells': '18.9', 'Exocrine glandular cells': '-0.653', 'Basal prostatic cells': '9.5', 'Prostatic glandular cells': '15.7', 'Breast glandular cells': '0.510', 'Breast myoepithelial cells': '0.248', 'Glandular and luminal cells': '45.0', 'Secretory cells': '7.8', 'Basal keratinocytes': '14.3', 'Suprabasal keratinocytes': '37.4', 'Basal squamous epithelial cells': '8.9', 'Squamous epithelial cells': '18.6', 'Alveolar cells type 1': '-0.014', 'Alveolar cells type 2': '0.189', 'Salivary duct cells': '16.7', 'Ductal cells': '0.524', 'Hepatocytes': '0.148', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.189', 'Distal tubular cells': '12.3', 'Collecting duct cells': '11.7', 'Mesothelial cells': '0.182', 'Sertoli cells': '-0.454', 'Granulosa cells': '9.5', 'Enteroendocrine cells': '22.0', 'Pancreatic endocrine cells': '34.0', 'Leydig cells': '-0.510', 'Excitatory neurons': '9.0', 'Inhibitory neurons': '14.6', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '7.1', 'Bipolar cells': '11.7', 'Horizontal cells': '16.4', 'Astrocytes': '8.4', 'Oligodendrocyte precursor cells': '6.1', 'Oligodendrocytes': '12.2', 'Microglial cells': '7.2', 'Muller glia cells': '18.4', 'Schwann cells': '0.055', 'Spermatogonia': '-0.237', 'Spermatocytes': '0.030', 'Early spermatids': '0.624', 'Late spermatids': '0.591', 'Oocytes': '19.9', 'Cytotrophoblasts': '63.3', 'Syncytiotrophoblasts': '189.5', 'Extravillous trophoblasts': '60.1', 'Endothelial cells': '12.5', 'Lymphatic endothelial cells': '10.7', 'Cardiomyocytes': '0.592', 'Skeletal myocytes': '-0.373', 'Smooth muscle cells': '14.0', 'Adipocytes': '10.2', 'Melanocytes': '0.024', 'Fibroblasts': '20.2', 'Peritubular cells': '-0.412', 'Endometrial stromal cells': '17.0', 'Ovarian stromal cells': '14.5', 'Undifferentiated cells': '11.3', 'T-cells': '19.0', 'B-cells': '11.7', 'Plasma cells': '7.0', 'Nk-cells': '11.4', 'Granulocytes': '12.5', 'Monocytes': '66.3', 'Macrophages': '44.1', 'Hofbauer cells': '67.6', 'Kupffer cells': '28.3', 'Dendritic cells': '18.1', 'Langerhans cells': '0.096', 'Erythroid cells': '0.088', 'Adipocytes (Subcutaneous)': '0.242', 'Adipocytes (Visceral)': '0.192', 'Breast glandular cells (progenitors)': '0.291', 'Adipocytes (Breast)': '-0.250', 'Colon enterocytes': '0.043', 'Colon enteroendocrine cells': '0.145', 'Enteric glia cells': '-0.185', 'Mitotic cells (Colon)': '0.075', 'Mitotic cells (Heart)': '0.416', 'Podocytes': '-0.169', 'Ascending Loop of Henle cells': '0.369', 'Intercalated cells': '-0.086', 'Cholangiocyte': '0.236', 'NK-cells (Liver)': '-0.221', 'Respiratory ciliated cells': '-0.123', 'Mitotic cells (Lung)': '-0.085', 'NK-cells (Lung)': '-0.184', 'B-cells (Lung)': '-0.139', 'Alpha cells': '0.409', 'Beta cells': '0.254', 'Prostate glandular cells': '0.340', 'Prostate basal glandular cells': '0.388', 'Urothelial cells': '0.177', 'Keratinocyte (other)': '0.283', 'Keratinocyte (granular)': '0.530', 'Hair cortex cells': '-0.207', 'Inner root sheath cells': '-0.264', 'Outer root sheath cells': '-0.374', 'Sebaceous gland cells': '-0.232', 'Eccrine sweat gland cells': '-0.335', 'Adipocytes (Skin)': '-0.174', 'Mitotic cells (Skin)': '-0.223', 'Parietal cells': '-0.573', 'Chief cells': '-0.489', 'Gastric mucous cells': '-0.304', 'Gastric enteroendocrine cells': '-0.354', 'Mitotic cells (Stomach)': '0.069', 'Parafollicular cells': '0.145', 'Thyroid glandular cells': '0.420', 'Mitotic cells (Thyroid)': '-0.090', 'Adrenal cortex cells': '0.272', 'Adrenal medulla cells': '0.128', 'Mitotic cells (Adrenal gland)': '0.174', 'Minor salivary glandular cells': '0.338', 'Minor salivary gland ductal cells': '-0.407', 'Minor salivary gland basal cells': '0.468', 'Mitotic cells (Minor salivary gland)': '0.576', 'Adipocytes (Minor salivary gland)': '0.119', 'Somatotropes': '0.187', 'Lactotropes': '0.074', 'Gonadotropes': '0.150', 'Corticotropes': '0.346', 'Thyrotropes': '0.156', 'Undifferentiated cells (Pituitary gland)': '-0.148', 'Mitotic cells (Spleen)': '-0.408', 'Platelets': '0.018', 'Erythrocytes': '-0.108', 'Hematopoietic stem cells': '-0.033', 'B-cells (Spleen)': '0.075', 'NK-cells (Spleen)': '0.048', 'Amygdala excitatory': '16.8', 'Cerebellar inhibitory': '30.6', 'Cge interneuron': '24.5', 'Deep-layer corticothalamic and 6b': '16.0', 'Deep-layer intratelencephalic': '16.8', 'Deep-layer near-projecting': '15.4', 'Eccentric medium spiny neuron': '14.4', 'Hippocampal ca1-3': '18.7', 'Hippocampal ca4': '16.3', 'Hippocampal dentate gyrus': '11.1', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '41.5', 'Mammillary body': '35.6', 'Medium spiny neuron': '14.5', 'Mge interneuron': '25.8', 'Midbrain-derived inhibitory': '22.9', 'Miscellaneous': '16.4', 'Splatter': '26.8', 'Thalamic excitatory': '27.5', 'Upper rhombic lip': '16.7', 'Upper-layer intratelencephalic': '14.0', 'Astrocyte': '27.0', 'Bergmann glia': '17.8', 'Central nervous system macrophage': '28.0', 'Choroid plexus epithelial cell': '29.7', 'Committed oligodendrocyte precursor': '22.2', 'Ependymal cell': '19.1', 'Oligodendrocyte': '23.0', 'Oligodendrocyte precursor cell': '16.7', 'Endothelial cell': '23.7', 'Pericyte': '23.7', 'Vascular associated smooth muscle cell': '17.3', 'Fibroblast': '19.3', 'Leukocyte': '30.9', 'Basophil': '60.7', 'Eosinophil': '44.6', 'Neutrophil': '452.8', 'Classical monocyte': '99.6', 'Non-classical monocyte': '33.4', 'Intermediate monocyte': '160.5', 'T-reg': '73.7', 'GdT-cell': '19.4', 'MAIT T-cell': '37.1', 'Memory CD4 T-cell': '29.6', 'Naive CD4 T-cell': '15.8', 'Memory CD8 T-cell': '18.4', 'Naive CD8 T-cell': '16.2', 'Memory B-cell': '13.7', 'Naive B-cell': '8.1', 'Plasmacytoid DC': '68.8', 'Myeloid DC': '99.6', 'NK-cell': '14.5', 'Total PBMC': '111.4', 'Vd2 gdTCR': '39.2', 'Memory CD4 T-cell Th1\\/Th17': '18.2', 'Memory CD4 T-cell Th17': '33.9', 'Memory CD4 T-cell Th2': '40.6', 'Non-Vd2 gdTCR': '46.5', 'Memory CD4 T-cell Th1': '31.7', 'Memory CD4 T-cell TFH': '50.4', 'Terminal effector memory CD4 T-cell': '38.2', 'Central memory CD8 T-cell': '46.7', 'Effector memory CD8 T-cell': '47.5', 'Terminal effector memory CD8 T-cell': '38.9', 'Non-switched memory B-cell': '47.4', 'Plasmablast': '14.4', 'Switched memory B-cell': '38.7', 'Exhausted memory B-cell': '37.6', 'Progenitor cell': '45.7', 'Memory T-reg': '57.7', 'Naive CD4 T-cell activated': '9.0', 'Naive CD8 T-cell activated': '8.5', 'Naive T-reg': '27.3'}
1ELK, 1WRD, 2N2N, 2N9D, 6J56
{'Adipose Tissue': 53.67264119601329, 'Adrenal Gland': 70.66135658914729, 'Bladder': 37.539047619047615, 'Blood': 96.07099461786868, 'Blood Vessel': 45.708906367041195, 'Brain': 31.01378955336866, 'Breast': 57.24054466230937, 'Cervix Uteri': 77.04105263157895, 'Colon': 30.388725288831836, 'Esophagus': 59.4972339100346, 'Fallopian Tube': 57.8111111111111, 'Heart': 34.59975609756098, 'Kidney': 39.659438202247195, 'Liver': 45.34119469026549, 'Lung': 79.57143598615917, 'Muscle': 147.38090909090909, 'Nerve': 46.87153473344103, 'Ovary': 44.815111111111115, 'Pancreas': 14.322631097560976, 'Pituitary': 76.06537102473499, 'Prostate': 51.64820408163265, 'Salivary Gland': 78.53895061728394, 'Skin': 94.9063128800442, 'Small Intestine': 40.619679144385024, 'Spleen': 47.476058091286305, 'Stomach': 26.901364902506963, 'Testis': 59.27437950138504, 'Thyroid': 59.28044410413476, 'Uterus': 55.0630985915493, 'Vagina': 84.53333333333333}
NAB2
MHRAPSPTAEQPPGGGDSARRTLQPRLKPSARAMALPRTLGELQLYRVLQRANLLSYYETFIQQGGDDVQQLCEAGEEEFLEIMALVGMATKPLHVRRLQKALREWATNPGLFSQPVPAVPVSSIPLFKISETAGTRKGSMSNGHGSPGEKAGSARSFSPKSPLELGEKLSPLPGGPGAGDPRIWPGRSTPESDVGAGGEEEAGSPPFSPPAGGGVPEGTGAGGLAAGGTGGGPDRLEPEMVRMVVESVERIFRSFPRGDAGEVTSLLKLNKKLARSVGHIFEMDDNDSQKEEEIRKYSIIYGRFDSKRREGKQLSLHELTINEAAAQFCMRDNTLLLRRVELFSLSRQVARESTYLSSLKGSRLHPEELGGPPLKKLKQEVGEQSHPEIQQPPPGPESYVPPYRPSLEEDSASLSGESLDGHLQAVGSCPRLTPPPADLPLALPAHGLWSRHILQQTLMDEGLRLARLVSHDRVGRLSPCVPAKPPLAEFEEGLLDRCPAPGPHPALVEGRRSSVKVEAEASRQ
Homo sapiens
Nucleus
Low tissue specificity
{'Ciliated cells': '12.1', 'Basal respiratory cells': '20.8', 'Club cells': '9.6', 'Ionocytes': '6.6', 'Mucus glandular cells': '4.7', 'Serous glandular cells': '6.1', 'Gastric mucus-secreting cells': '10.0', 'Proximal enterocytes': '6.1', 'Paneth cells': '0.0', 'Distal enterocytes': '0.4', 'Intestinal goblet cells': '0.7', 'Exocrine glandular cells': '-0.500', 'Basal prostatic cells': '18.0', 'Prostatic glandular cells': '5.9', 'Breast glandular cells': '0.511', 'Breast myoepithelial cells': '0.634', 'Glandular and luminal cells': '24.1', 'Secretory cells': '13.8', 'Basal keratinocytes': '21.9', 'Suprabasal keratinocytes': '22.3', 'Basal squamous epithelial cells': '32.1', 'Squamous epithelial cells': '19.3', 'Alveolar cells type 1': '0.086', 'Alveolar cells type 2': '-0.418', 'Salivary duct cells': '9.3', 'Ductal cells': '0.641', 'Hepatocytes': '0.110', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.105', 'Distal tubular cells': '9.2', 'Collecting duct cells': '7.8', 'Mesothelial cells': '0.489', 'Sertoli cells': '0.674', 'Granulosa cells': '16.3', 'Enteroendocrine cells': '0.9', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.574', 'Excitatory neurons': '11.0', 'Inhibitory neurons': '5.2', 'Cone photoreceptor cells': '1.7', 'Rod photoreceptor cells': '3.6', 'Bipolar cells': '17.7', 'Horizontal cells': '13.8', 'Astrocytes': '5.6', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '1.8', 'Microglial cells': '8.1', 'Muller glia cells': '8.5', 'Schwann cells': '0.174', 'Spermatogonia': '0.409', 'Spermatocytes': '-0.081', 'Early spermatids': '-0.549', 'Late spermatids': '-0.642', 'Oocytes': '2.2', 'Cytotrophoblasts': '3.9', 'Syncytiotrophoblasts': '49.9', 'Extravillous trophoblasts': '11.0', 'Endothelial cells': '13.8', 'Lymphatic endothelial cells': '1.6', 'Cardiomyocytes': '0.136', 'Skeletal myocytes': '0.108', 'Smooth muscle cells': '14.1', 'Adipocytes': '8.0', 'Melanocytes': '0.186', 'Fibroblasts': '18.5', 'Peritubular cells': '0.629', 'Endometrial stromal cells': '19.8', 'Ovarian stromal cells': '26.2', 'Undifferentiated cells': '2.6', 'T-cells': '9.0', 'B-cells': '12.6', 'Plasma cells': '5.8', 'Nk-cells': '3.0', 'Granulocytes': '15.9', 'Monocytes': '14.7', 'Macrophages': '14.0', 'Hofbauer cells': '11.1', 'Kupffer cells': '12.5', 'Dendritic cells': '1.6', 'Langerhans cells': '0.123', 'Erythroid cells': '0.014', 'Adipocytes (Subcutaneous)': '-0.530', 'Adipocytes (Visceral)': '-0.501', 'Breast glandular cells (progenitors)': '0.412', 'Adipocytes (Breast)': '-0.624', 'Colon enterocytes': '-0.271', 'Colon enteroendocrine cells': '0.160', 'Enteric glia cells': '0.543', 'Mitotic cells (Colon)': '-0.276', 'Mitotic cells (Heart)': '0.374', 'Podocytes': '0.033', 'Ascending Loop of Henle cells': '0.302', 'Intercalated cells': '0.000', 'Cholangiocyte': '0.322', 'NK-cells (Liver)': '-0.090', 'Respiratory ciliated cells': '0.044', 'Mitotic cells (Lung)': '-0.137', 'NK-cells (Lung)': '0.333', 'B-cells (Lung)': '0.148', 'Alpha cells': '0.407', 'Beta cells': '0.215', 'Prostate glandular cells': '-0.362', 'Prostate basal glandular cells': '0.007', 'Urothelial cells': '0.223', 'Keratinocyte (other)': '0.449', 'Keratinocyte (granular)': '-0.087', 'Hair cortex cells': '-0.110', 'Inner root sheath cells': '-0.059', 'Outer root sheath cells': '0.067', 'Sebaceous gland cells': '-0.178', 'Eccrine sweat gland cells': '-0.291', 'Adipocytes (Skin)': '-0.415', 'Mitotic cells (Skin)': '0.304', 'Parietal cells': '-0.749', 'Chief cells': '-0.566', 'Gastric mucous cells': '-0.603', 'Gastric enteroendocrine cells': '-0.429', 'Mitotic cells (Stomach)': '-0.197', 'Parafollicular cells': '-0.010', 'Thyroid glandular cells': '-0.033', 'Mitotic cells (Thyroid)': '0.026', 'Adrenal cortex cells': '0.256', 'Adrenal medulla cells': '0.072', 'Mitotic cells (Adrenal gland)': '-0.267', 'Minor salivary glandular cells': '0.160', 'Minor salivary gland ductal cells': '-0.189', 'Minor salivary gland basal cells': '0.560', 'Mitotic cells (Minor salivary gland)': '0.550', 'Adipocytes (Minor salivary gland)': '0.247', 'Somatotropes': '-0.210', 'Lactotropes': '-0.160', 'Gonadotropes': '0.202', 'Corticotropes': '-0.240', 'Thyrotropes': '-0.040', 'Undifferentiated cells (Pituitary gland)': '0.314', 'Mitotic cells (Spleen)': '-0.330', 'Platelets': '-0.232', 'Erythrocytes': '-0.071', 'Hematopoietic stem cells': '-0.328', 'B-cells (Spleen)': '0.303', 'NK-cells (Spleen)': '0.154', 'Amygdala excitatory': '17.5', 'Cerebellar inhibitory': '5.9', 'Cge interneuron': '9.7', 'Deep-layer corticothalamic and 6b': '15.5', 'Deep-layer intratelencephalic': '17.8', 'Deep-layer near-projecting': '10.9', 'Eccentric medium spiny neuron': '17.1', 'Hippocampal ca1-3': '17.8', 'Hippocampal ca4': '16.7', 'Hippocampal dentate gyrus': '16.7', 'Lamp5-lhx6 and chandelier': '14.0', 'Lower rhombic lip': '6.2', 'Mammillary body': '11.2', 'Medium spiny neuron': '19.8', 'Mge interneuron': '9.2', 'Midbrain-derived inhibitory': '3.5', 'Miscellaneous': '17.4', 'Splatter': '8.5', 'Thalamic excitatory': '10.8', 'Upper rhombic lip': '25.0', 'Upper-layer intratelencephalic': '17.7', 'Astrocyte': '10.9', 'Bergmann glia': '5.9', 'Central nervous system macrophage': '12.4', 'Choroid plexus epithelial cell': '1.3', 'Committed oligodendrocyte precursor': '4.0', 'Ependymal cell': '6.3', 'Oligodendrocyte': '1.6', 'Oligodendrocyte precursor cell': '4.2', 'Endothelial cell': '7.3', 'Pericyte': '16.0', 'Vascular associated smooth muscle cell': '15.1', 'Fibroblast': '13.7', 'Leukocyte': '7.4', 'Basophil': '0.2', 'Eosinophil': '0.2', 'Neutrophil': '2.8', 'Classical monocyte': '30.2', 'Non-classical monocyte': '19.6', 'Intermediate monocyte': '7.3', 'T-reg': '2.1', 'GdT-cell': '0.5', 'MAIT T-cell': '3.5', 'Memory CD4 T-cell': '0.9', 'Naive CD4 T-cell': '8.7', 'Memory CD8 T-cell': '0.7', 'Naive CD8 T-cell': '14.3', 'Memory B-cell': '0.9', 'Naive B-cell': '5.8', 'Plasmacytoid DC': '0.4', 'Myeloid DC': '7.4', 'NK-cell': '12.2', 'Total PBMC': '3.9', 'Vd2 gdTCR': '3.6', 'Memory CD4 T-cell Th1\\/Th17': '6.0', 'Memory CD4 T-cell Th17': '9.2', 'Memory CD4 T-cell Th2': '11.2', 'Non-Vd2 gdTCR': '2.0', 'Memory CD4 T-cell Th1': '9.7', 'Memory CD4 T-cell TFH': '12.9', 'Terminal effector memory CD4 T-cell': '0.7', 'Central memory CD8 T-cell': '2.4', 'Effector memory CD8 T-cell': '2.1', 'Terminal effector memory CD8 T-cell': '1.7', 'Non-switched memory B-cell': '2.9', 'Plasmablast': '0.9', 'Switched memory B-cell': '1.8', 'Exhausted memory B-cell': '3.5', 'Progenitor cell': '3.9', 'Memory T-reg': '11.3', 'Naive CD4 T-cell activated': '66.8', 'Naive CD8 T-cell activated': '94.3', 'Naive T-reg': '10.5'}
null
{'Adipose Tissue': 34.01690365448505, 'Adrenal Gland': 22.542011627906977, 'Bladder': 55.808571428571426, 'Blood': 12.43420182992465, 'Blood Vessel': 72.01005243445692, 'Brain': 35.73386828160485, 'Breast': 29.61433551198257, 'Cervix Uteri': 83.81947368421052, 'Colon': 42.65113607188704, 'Esophagus': 44.31318546712803, 'Fallopian Tube': 76.29777777777778, 'Heart': 14.953149825783973, 'Kidney': 23.182168539325843, 'Liver': 15.178805309734512, 'Lung': 53.92046712802768, 'Muscle': 6.4993337484433376, 'Nerve': 80.03588045234248, 'Ovary': 116.46794444444444, 'Pancreas': 4.849847256097561, 'Pituitary': 72.59427561837455, 'Prostate': 54.17404081632653, 'Salivary Gland': 19.666246913580245, 'Skin': 66.51001105583195, 'Small Intestine': 29.9265935828877, 'Spleen': 32.12307053941909, 'Stomach': 25.024874651810585, 'Testis': 43.01612742382272, 'Thyroid': 50.6145574272588, 'Uterus': 96.10239436619716, 'Vagina': 73.66967948717948}
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null
In a complex with TOLLIP
null
null
TOLLIP, MYO6, TAX1BP1, CALCOCO2, OPTN, ZFYVE16, LRBA
null
null
null
null
null
null
70.917317
0.543862
62.716286
0.695867
1,493
O60784
Q99741
23129771
UbiNet, UbiBrowser
TOM1
MDFLLGNPFSSPVGQRIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVTIYEDLRRKGLEFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQQEDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQAEPADLELLQELNRTCRAMQQRVLELIPQIANEQLTEELLIVNDNLNNVFLRHERFERFRTGQTTKAPSEAEPAADLIDMGPDPAATGNLSSQLAGMNLGSSSVRAGLQSLEASGRLEDEFDMFALTRGSSLADQRKEVKYEAPQATDGLAGALDARQQSTGAIPVTQACLMEDIEQWLSTDVGNDAEEPKGVTSEEFDKFLEERAKAADRLPNLSSPSAEGPPGPPSGPAPRKKTQEKDDDMLFAL
Homo sapiens
Cytoplasm, Endosome membrane, Early endosome membrane
Tissue enhanced (skeletal)
{'Ciliated cells': '24.4', 'Basal respiratory cells': '28.0', 'Club cells': '23.0', 'Ionocytes': '54.9', 'Mucus glandular cells': '41.5', 'Serous glandular cells': '17.6', 'Gastric mucus-secreting cells': '14.7', 'Proximal enterocytes': '52.9', 'Paneth cells': '16.8', 'Distal enterocytes': '39.0', 'Intestinal goblet cells': '18.9', 'Exocrine glandular cells': '-0.653', 'Basal prostatic cells': '9.5', 'Prostatic glandular cells': '15.7', 'Breast glandular cells': '0.510', 'Breast myoepithelial cells': '0.248', 'Glandular and luminal cells': '45.0', 'Secretory cells': '7.8', 'Basal keratinocytes': '14.3', 'Suprabasal keratinocytes': '37.4', 'Basal squamous epithelial cells': '8.9', 'Squamous epithelial cells': '18.6', 'Alveolar cells type 1': '-0.014', 'Alveolar cells type 2': '0.189', 'Salivary duct cells': '16.7', 'Ductal cells': '0.524', 'Hepatocytes': '0.148', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.189', 'Distal tubular cells': '12.3', 'Collecting duct cells': '11.7', 'Mesothelial cells': '0.182', 'Sertoli cells': '-0.454', 'Granulosa cells': '9.5', 'Enteroendocrine cells': '22.0', 'Pancreatic endocrine cells': '34.0', 'Leydig cells': '-0.510', 'Excitatory neurons': '9.0', 'Inhibitory neurons': '14.6', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '7.1', 'Bipolar cells': '11.7', 'Horizontal cells': '16.4', 'Astrocytes': '8.4', 'Oligodendrocyte precursor cells': '6.1', 'Oligodendrocytes': '12.2', 'Microglial cells': '7.2', 'Muller glia cells': '18.4', 'Schwann cells': '0.055', 'Spermatogonia': '-0.237', 'Spermatocytes': '0.030', 'Early spermatids': '0.624', 'Late spermatids': '0.591', 'Oocytes': '19.9', 'Cytotrophoblasts': '63.3', 'Syncytiotrophoblasts': '189.5', 'Extravillous trophoblasts': '60.1', 'Endothelial cells': '12.5', 'Lymphatic endothelial cells': '10.7', 'Cardiomyocytes': '0.592', 'Skeletal myocytes': '-0.373', 'Smooth muscle cells': '14.0', 'Adipocytes': '10.2', 'Melanocytes': '0.024', 'Fibroblasts': '20.2', 'Peritubular cells': '-0.412', 'Endometrial stromal cells': '17.0', 'Ovarian stromal cells': '14.5', 'Undifferentiated cells': '11.3', 'T-cells': '19.0', 'B-cells': '11.7', 'Plasma cells': '7.0', 'Nk-cells': '11.4', 'Granulocytes': '12.5', 'Monocytes': '66.3', 'Macrophages': '44.1', 'Hofbauer cells': '67.6', 'Kupffer cells': '28.3', 'Dendritic cells': '18.1', 'Langerhans cells': '0.096', 'Erythroid cells': '0.088', 'Adipocytes (Subcutaneous)': '0.242', 'Adipocytes (Visceral)': '0.192', 'Breast glandular cells (progenitors)': '0.291', 'Adipocytes (Breast)': '-0.250', 'Colon enterocytes': '0.043', 'Colon enteroendocrine cells': '0.145', 'Enteric glia cells': '-0.185', 'Mitotic cells (Colon)': '0.075', 'Mitotic cells (Heart)': '0.416', 'Podocytes': '-0.169', 'Ascending Loop of Henle cells': '0.369', 'Intercalated cells': '-0.086', 'Cholangiocyte': '0.236', 'NK-cells (Liver)': '-0.221', 'Respiratory ciliated cells': '-0.123', 'Mitotic cells (Lung)': '-0.085', 'NK-cells (Lung)': '-0.184', 'B-cells (Lung)': '-0.139', 'Alpha cells': '0.409', 'Beta cells': '0.254', 'Prostate glandular cells': '0.340', 'Prostate basal glandular cells': '0.388', 'Urothelial cells': '0.177', 'Keratinocyte (other)': '0.283', 'Keratinocyte (granular)': '0.530', 'Hair cortex cells': '-0.207', 'Inner root sheath cells': '-0.264', 'Outer root sheath cells': '-0.374', 'Sebaceous gland cells': '-0.232', 'Eccrine sweat gland cells': '-0.335', 'Adipocytes (Skin)': '-0.174', 'Mitotic cells (Skin)': '-0.223', 'Parietal cells': '-0.573', 'Chief cells': '-0.489', 'Gastric mucous cells': '-0.304', 'Gastric enteroendocrine cells': '-0.354', 'Mitotic cells (Stomach)': '0.069', 'Parafollicular cells': '0.145', 'Thyroid glandular cells': '0.420', 'Mitotic cells (Thyroid)': '-0.090', 'Adrenal cortex cells': '0.272', 'Adrenal medulla cells': '0.128', 'Mitotic cells (Adrenal gland)': '0.174', 'Minor salivary glandular cells': '0.338', 'Minor salivary gland ductal cells': '-0.407', 'Minor salivary gland basal cells': '0.468', 'Mitotic cells (Minor salivary gland)': '0.576', 'Adipocytes (Minor salivary gland)': '0.119', 'Somatotropes': '0.187', 'Lactotropes': '0.074', 'Gonadotropes': '0.150', 'Corticotropes': '0.346', 'Thyrotropes': '0.156', 'Undifferentiated cells (Pituitary gland)': '-0.148', 'Mitotic cells (Spleen)': '-0.408', 'Platelets': '0.018', 'Erythrocytes': '-0.108', 'Hematopoietic stem cells': '-0.033', 'B-cells (Spleen)': '0.075', 'NK-cells (Spleen)': '0.048', 'Amygdala excitatory': '16.8', 'Cerebellar inhibitory': '30.6', 'Cge interneuron': '24.5', 'Deep-layer corticothalamic and 6b': '16.0', 'Deep-layer intratelencephalic': '16.8', 'Deep-layer near-projecting': '15.4', 'Eccentric medium spiny neuron': '14.4', 'Hippocampal ca1-3': '18.7', 'Hippocampal ca4': '16.3', 'Hippocampal dentate gyrus': '11.1', 'Lamp5-lhx6 and chandelier': '22.8', 'Lower rhombic lip': '41.5', 'Mammillary body': '35.6', 'Medium spiny neuron': '14.5', 'Mge interneuron': '25.8', 'Midbrain-derived inhibitory': '22.9', 'Miscellaneous': '16.4', 'Splatter': '26.8', 'Thalamic excitatory': '27.5', 'Upper rhombic lip': '16.7', 'Upper-layer intratelencephalic': '14.0', 'Astrocyte': '27.0', 'Bergmann glia': '17.8', 'Central nervous system macrophage': '28.0', 'Choroid plexus epithelial cell': '29.7', 'Committed oligodendrocyte precursor': '22.2', 'Ependymal cell': '19.1', 'Oligodendrocyte': '23.0', 'Oligodendrocyte precursor cell': '16.7', 'Endothelial cell': '23.7', 'Pericyte': '23.7', 'Vascular associated smooth muscle cell': '17.3', 'Fibroblast': '19.3', 'Leukocyte': '30.9', 'Basophil': '60.7', 'Eosinophil': '44.6', 'Neutrophil': '452.8', 'Classical monocyte': '99.6', 'Non-classical monocyte': '33.4', 'Intermediate monocyte': '160.5', 'T-reg': '73.7', 'GdT-cell': '19.4', 'MAIT T-cell': '37.1', 'Memory CD4 T-cell': '29.6', 'Naive CD4 T-cell': '15.8', 'Memory CD8 T-cell': '18.4', 'Naive CD8 T-cell': '16.2', 'Memory B-cell': '13.7', 'Naive B-cell': '8.1', 'Plasmacytoid DC': '68.8', 'Myeloid DC': '99.6', 'NK-cell': '14.5', 'Total PBMC': '111.4', 'Vd2 gdTCR': '39.2', 'Memory CD4 T-cell Th1\\/Th17': '18.2', 'Memory CD4 T-cell Th17': '33.9', 'Memory CD4 T-cell Th2': '40.6', 'Non-Vd2 gdTCR': '46.5', 'Memory CD4 T-cell Th1': '31.7', 'Memory CD4 T-cell TFH': '50.4', 'Terminal effector memory CD4 T-cell': '38.2', 'Central memory CD8 T-cell': '46.7', 'Effector memory CD8 T-cell': '47.5', 'Terminal effector memory CD8 T-cell': '38.9', 'Non-switched memory B-cell': '47.4', 'Plasmablast': '14.4', 'Switched memory B-cell': '38.7', 'Exhausted memory B-cell': '37.6', 'Progenitor cell': '45.7', 'Memory T-reg': '57.7', 'Naive CD4 T-cell activated': '9.0', 'Naive CD8 T-cell activated': '8.5', 'Naive T-reg': '27.3'}
1ELK, 1WRD, 2N2N, 2N9D, 6J56
{'Adipose Tissue': 53.67264119601329, 'Adrenal Gland': 70.66135658914729, 'Bladder': 37.539047619047615, 'Blood': 96.07099461786868, 'Blood Vessel': 45.708906367041195, 'Brain': 31.01378955336866, 'Breast': 57.24054466230937, 'Cervix Uteri': 77.04105263157895, 'Colon': 30.388725288831836, 'Esophagus': 59.4972339100346, 'Fallopian Tube': 57.8111111111111, 'Heart': 34.59975609756098, 'Kidney': 39.659438202247195, 'Liver': 45.34119469026549, 'Lung': 79.57143598615917, 'Muscle': 147.38090909090909, 'Nerve': 46.87153473344103, 'Ovary': 44.815111111111115, 'Pancreas': 14.322631097560976, 'Pituitary': 76.06537102473499, 'Prostate': 51.64820408163265, 'Salivary Gland': 78.53895061728394, 'Skin': 94.9063128800442, 'Small Intestine': 40.619679144385024, 'Spleen': 47.476058091286305, 'Stomach': 26.901364902506963, 'Testis': 59.27437950138504, 'Thyroid': 59.28044410413476, 'Uterus': 55.0630985915493, 'Vagina': 84.53333333333333}
CDC6
MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLGDDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDKALIGNILATGLP
Homo sapiens
Nucleus, Cytoplasm
Tissue enhanced (bone marrow, lymphoid tissue)
{'Ciliated cells': '0.4', 'Basal respiratory cells': '3.6', 'Club cells': '1.6', 'Ionocytes': '0.7', 'Mucus glandular cells': '1.3', 'Serous glandular cells': '0.7', 'Gastric mucus-secreting cells': '3.5', 'Proximal enterocytes': '0.5', 'Paneth cells': '1.8', 'Distal enterocytes': '3.6', 'Intestinal goblet cells': '6.2', 'Exocrine glandular cells': '-0.490', 'Basal prostatic cells': '0.7', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.231', 'Breast myoepithelial cells': '0.343', 'Glandular and luminal cells': '4.9', 'Secretory cells': '0.8', 'Basal keratinocytes': '5.8', 'Suprabasal keratinocytes': '2.4', 'Basal squamous epithelial cells': '4.4', 'Squamous epithelial cells': '8.6', 'Alveolar cells type 1': '-0.330', 'Alveolar cells type 2': '0.024', 'Salivary duct cells': '1.4', 'Ductal cells': '0.373', 'Hepatocytes': '0.272', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.148', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.071', 'Sertoli cells': '0.170', 'Granulosa cells': '1.1', 'Enteroendocrine cells': '1.6', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.193', 'Excitatory neurons': '1.9', 'Inhibitory neurons': '0.6', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.3', 'Bipolar cells': '0.2', 'Horizontal cells': '0.6', 'Astrocytes': '0.6', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.2', 'Microglial cells': '0.0', 'Muller glia cells': '0.5', 'Schwann cells': '-0.019', 'Spermatogonia': '0.432', 'Spermatocytes': '0.787', 'Early spermatids': '-0.067', 'Late spermatids': '-0.213', 'Oocytes': '53.7', 'Cytotrophoblasts': '25.2', 'Syncytiotrophoblasts': '18.4', 'Extravillous trophoblasts': '35.1', 'Endothelial cells': '1.6', 'Lymphatic endothelial cells': '1.1', 'Cardiomyocytes': '0.160', 'Skeletal myocytes': '-0.069', 'Smooth muscle cells': '1.8', 'Adipocytes': '1.9', 'Melanocytes': '0.441', 'Fibroblasts': '4.6', 'Peritubular cells': '0.039', 'Endometrial stromal cells': '2.4', 'Ovarian stromal cells': '1.2', 'Undifferentiated cells': '22.6', 'T-cells': '2.2', 'B-cells': '3.5', 'Plasma cells': '32.6', 'Nk-cells': '2.2', 'Granulocytes': '0.1', 'Monocytes': '0.2', 'Macrophages': '1.5', 'Hofbauer cells': '6.1', 'Kupffer cells': '1.1', 'Dendritic cells': '0.4', 'Langerhans cells': '0.193', 'Erythroid cells': '-0.127', 'Adipocytes (Subcutaneous)': '-0.364', 'Adipocytes (Visceral)': '-0.236', 'Breast glandular cells (progenitors)': '0.314', 'Adipocytes (Breast)': '-0.351', 'Colon enterocytes': '0.268', 'Colon enteroendocrine cells': '-0.009', 'Enteric glia cells': '-0.034', 'Mitotic cells (Colon)': '0.555', 'Mitotic cells (Heart)': '0.582', 'Podocytes': '-0.139', 'Ascending Loop of Henle cells': '0.218', 'Intercalated cells': '-0.153', 'Cholangiocyte': '0.258', 'NK-cells (Liver)': '-0.293', 'Respiratory ciliated cells': '-0.064', 'Mitotic cells (Lung)': '0.542', 'NK-cells (Lung)': '-0.154', 'B-cells (Lung)': '-0.043', 'Alpha cells': '0.191', 'Beta cells': '0.090', 'Prostate glandular cells': '0.072', 'Prostate basal glandular cells': '0.221', 'Urothelial cells': '0.248', 'Keratinocyte (other)': '0.219', 'Keratinocyte (granular)': '-0.260', 'Hair cortex cells': '0.240', 'Inner root sheath cells': '0.359', 'Outer root sheath cells': '0.406', 'Sebaceous gland cells': '0.171', 'Eccrine sweat gland cells': '0.051', 'Adipocytes (Skin)': '-0.140', 'Mitotic cells (Skin)': '0.766', 'Parietal cells': '-0.085', 'Chief cells': '0.049', 'Gastric mucous cells': '0.375', 'Gastric enteroendocrine cells': '0.150', 'Mitotic cells (Stomach)': '0.765', 'Parafollicular cells': '-0.057', 'Thyroid glandular cells': '-0.138', 'Mitotic cells (Thyroid)': '0.373', 'Adrenal cortex cells': '0.398', 'Adrenal medulla cells': '-0.021', 'Mitotic cells (Adrenal gland)': '0.431', 'Minor salivary glandular cells': '0.116', 'Minor salivary gland ductal cells': '-0.222', 'Minor salivary gland basal cells': '0.615', 'Mitotic cells (Minor salivary gland)': '0.784', 'Adipocytes (Minor salivary gland)': '0.160', 'Somatotropes': '-0.152', 'Lactotropes': '-0.176', 'Gonadotropes': '0.171', 'Corticotropes': '-0.194', 'Thyrotropes': '-0.146', 'Undifferentiated cells (Pituitary gland)': '0.330', 'Mitotic cells (Spleen)': '0.827', 'Platelets': '0.156', 'Erythrocytes': '0.285', 'Hematopoietic stem cells': '0.230', 'B-cells (Spleen)': '-0.206', 'NK-cells (Spleen)': '-0.219', 'Amygdala excitatory': '2.8', 'Cerebellar inhibitory': '0.6', 'Cge interneuron': '1.0', 'Deep-layer corticothalamic and 6b': '1.6', 'Deep-layer intratelencephalic': '2.9', 'Deep-layer near-projecting': '1.5', 'Eccentric medium spiny neuron': '1.2', 'Hippocampal ca1-3': '1.9', 'Hippocampal ca4': '1.5', 'Hippocampal dentate gyrus': '1.9', 'Lamp5-lhx6 and chandelier': '1.2', 'Lower rhombic lip': '1.1', 'Mammillary body': '1.2', 'Medium spiny neuron': '1.4', 'Mge interneuron': '1.1', 'Midbrain-derived inhibitory': '0.7', 'Miscellaneous': '2.4', 'Splatter': '1.3', 'Thalamic excitatory': '1.8', 'Upper rhombic lip': '1.4', 'Upper-layer intratelencephalic': '5.4', 'Astrocyte': '1.9', 'Bergmann glia': '1.0', 'Central nervous system macrophage': '0.5', 'Choroid plexus epithelial cell': '0.1', 'Committed oligodendrocyte precursor': '0.4', 'Ependymal cell': '1.1', 'Oligodendrocyte': '0.3', 'Oligodendrocyte precursor cell': '0.5', 'Endothelial cell': '0.4', 'Pericyte': '0.4', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.2', 'Leukocyte': '0.6', 'Basophil': '0.6', 'Eosinophil': '0.0', 'Neutrophil': '0.4', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.3', 'Intermediate monocyte': '1.5', 'T-reg': '4.1', 'GdT-cell': '0.8', 'MAIT T-cell': '3.0', 'Memory CD4 T-cell': '0.6', 'Naive CD4 T-cell': '0.4', 'Memory CD8 T-cell': '1.1', 'Naive CD8 T-cell': '0.4', 'Memory B-cell': '0.4', 'Naive B-cell': '0.5', 'Plasmacytoid DC': '7.4', 'Myeloid DC': '0.9', 'NK-cell': '1.9', 'Total PBMC': '5.3', 'Vd2 gdTCR': '0.2', 'Memory CD4 T-cell TFH': '0.4', 'Memory CD4 T-cell Th2': '0.8', 'Memory CD4 T-cell Th17': '0.7', 'Memory CD4 T-cell Th1\\/Th17': '0.7', 'Non-Vd2 gdTCR': '3.2', 'Memory CD4 T-cell Th1': '1.3', 'Terminal effector memory CD4 T-cell': '1.2', 'Central memory CD8 T-cell': '1.7', 'Effector memory CD8 T-cell': '8.7', 'Terminal effector memory CD8 T-cell': '1.5', 'Switched memory B-cell': '3.3', 'Plasmablast': '94.4', 'Non-switched memory B-cell': '0.6', 'Exhausted memory B-cell': '4.9', 'Progenitor cell': '4.1', 'Naive CD4 T-cell activated': '1.0', 'Naive CD8 T-cell activated': '1.2', 'Memory T-reg': '2.1', 'Naive T-reg': '0.5'}
2CCH, 2CCI, 4I5L, 4I5N, 8HT7
{'Adipose Tissue': 1.0135120598006646, 'Adrenal Gland': 1.476743023255814, 'Bladder': 1.1341238095238095, 'Blood': 5.327745414424112, 'Blood Vessel': 0.5764714232209738, 'Brain': 0.7258613058289175, 'Breast': 0.8094962745098039, 'Cervix Uteri': 1.461278947368421, 'Colon': 1.3525910141206676, 'Esophagus': 2.140787570934256, 'Fallopian Tube': 0.9588, 'Heart': 0.4529019512195122, 'Kidney': 0.4478088764044944, 'Liver': 1.4233409292035395, 'Lung': 2.030225605536332, 'Muscle': 0.2054580946450809, 'Nerve': 0.7501828756058159, 'Ovary': 0.9998522222222224, 'Pancreas': 0.8700864024390245, 'Pituitary': 0.6330436042402827, 'Prostate': 0.9005502857142856, 'Salivary Gland': 1.3956925925925927, 'Skin': 5.488745605306799, 'Small Intestine': 2.64122192513369, 'Spleen': 5.095452697095436, 'Stomach': 1.377367409470752, 'Testis': 10.918598337950138, 'Thyroid': 0.8930437212863707, 'Uterus': 0.754343661971831, 'Vagina': 2.244133333333333}
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null
In a complex with TOLLIP
null
null
TOLLIP, MYO6, TAX1BP1, CALCOCO2, OPTN, ZFYVE16, LRBA
null
null
null
null
null
null
70.917317
0.543862
69.693054
0.520054
1,384
O60858
O60858
31744379
UbiNet, UbiBrowser
TRIM13
MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '35.7', 'Basal respiratory cells': '46.2', 'Club cells': '36.4', 'Ionocytes': '45.3', 'Mucus glandular cells': '19.6', 'Serous glandular cells': '21.6', 'Gastric mucus-secreting cells': '13.6', 'Proximal enterocytes': '19.2', 'Paneth cells': '22.6', 'Distal enterocytes': '29.5', 'Intestinal goblet cells': '26.4', 'Exocrine glandular cells': '-0.691', 'Basal prostatic cells': '38.4', 'Prostatic glandular cells': '57.3', 'Breast glandular cells': '0.654', 'Breast myoepithelial cells': '0.557', 'Glandular and luminal cells': '14.3', 'Secretory cells': '25.7', 'Basal keratinocytes': '24.6', 'Suprabasal keratinocytes': '37.3', 'Basal squamous epithelial cells': '21.3', 'Squamous epithelial cells': '30.7', 'Alveolar cells type 1': '0.156', 'Alveolar cells type 2': '0.058', 'Salivary duct cells': '18.9', 'Ductal cells': '0.609', 'Hepatocytes': '0.096', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.335', 'Distal tubular cells': '12.3', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.408', 'Sertoli cells': '-0.535', 'Granulosa cells': '46.9', 'Enteroendocrine cells': '31.8', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '-0.547', 'Excitatory neurons': '29.5', 'Inhibitory neurons': '28.3', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '56.5', 'Bipolar cells': '22.0', 'Horizontal cells': '15.7', 'Astrocytes': '19.8', 'Oligodendrocyte precursor cells': '42.9', 'Oligodendrocytes': '53.5', 'Microglial cells': '34.0', 'Muller glia cells': '13.8', 'Schwann cells': '0.150', 'Spermatogonia': '-0.307', 'Spermatocytes': '0.084', 'Early spermatids': '0.882', 'Late spermatids': '0.649', 'Oocytes': '26.5', 'Cytotrophoblasts': '33.3', 'Syncytiotrophoblasts': '33.7', 'Extravillous trophoblasts': '16.6', 'Endothelial cells': '29.9', 'Lymphatic endothelial cells': '18.0', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '-0.188', 'Smooth muscle cells': '26.6', 'Adipocytes': '31.3', 'Melanocytes': '0.133', 'Fibroblasts': '24.1', 'Peritubular cells': '-0.360', 'Endometrial stromal cells': '23.3', 'Ovarian stromal cells': '27.9', 'Undifferentiated cells': '22.8', 'T-cells': '25.5', 'B-cells': '37.6', 'Plasma cells': '11.7', 'Nk-cells': '26.4', 'Granulocytes': '41.3', 'Monocytes': '32.1', 'Macrophages': '22.1', 'Hofbauer cells': '17.9', 'Kupffer cells': '16.8', 'Dendritic cells': '30.3', 'Langerhans cells': '0.265', 'Erythroid cells': '0.064', 'Adipocytes (Subcutaneous)': '-0.207', 'Adipocytes (Visceral)': '-0.380', 'Breast glandular cells (progenitors)': '0.416', 'Adipocytes (Breast)': '-0.618', 'Colon enterocytes': '0.048', 'Colon enteroendocrine cells': '0.141', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '0.151', 'Mitotic cells (Heart)': '0.485', 'Podocytes': '-0.163', 'Ascending Loop of Henle cells': '0.354', 'Intercalated cells': '-0.112', 'Cholangiocyte': '0.172', 'NK-cells (Liver)': '-0.079', 'Respiratory ciliated cells': '0.210', 'Mitotic cells (Lung)': '-0.007', 'NK-cells (Lung)': '0.157', 'B-cells (Lung)': '0.054', 'Alpha cells': '0.429', 'Beta cells': '0.264', 'Prostate glandular cells': '0.412', 'Prostate basal glandular cells': '0.532', 'Urothelial cells': '0.131', 'Keratinocyte (other)': '0.381', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.340', 'Inner root sheath cells': '-0.257', 'Outer root sheath cells': '-0.142', 'Sebaceous gland cells': '0.001', 'Eccrine sweat gland cells': '-0.215', 'Adipocytes (Skin)': '-0.313', 'Mitotic cells (Skin)': '0.144', 'Parietal cells': '-0.382', 'Chief cells': '-0.347', 'Gastric mucous cells': '-0.142', 'Gastric enteroendocrine cells': '-0.174', 'Mitotic cells (Stomach)': '0.162', 'Parafollicular cells': '-0.014', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '-0.007', 'Adrenal cortex cells': '0.320', 'Adrenal medulla cells': '0.018', 'Mitotic cells (Adrenal gland)': '0.240', 'Minor salivary glandular cells': '0.254', 'Minor salivary gland ductal cells': '0.032', 'Minor salivary gland basal cells': '0.575', 'Mitotic cells (Minor salivary gland)': '0.491', 'Adipocytes (Minor salivary gland)': '0.133', 'Somatotropes': '-0.167', 'Lactotropes': '-0.121', 'Gonadotropes': '-0.119', 'Corticotropes': '0.059', 'Thyrotropes': '0.127', 'Undifferentiated cells (Pituitary gland)': '0.293', 'Mitotic cells (Spleen)': '-0.249', 'Platelets': '-0.180', 'Erythrocytes': '-0.123', 'Hematopoietic stem cells': '-0.320', 'B-cells (Spleen)': '0.551', 'NK-cells (Spleen)': '0.395', 'Amygdala excitatory': '39.5', 'Cerebellar inhibitory': '26.5', 'Cge interneuron': '39.4', 'Deep-layer corticothalamic and 6b': '39.2', 'Deep-layer intratelencephalic': '35.2', 'Deep-layer near-projecting': '36.9', 'Eccentric medium spiny neuron': '41.9', 'Hippocampal ca1-3': '42.3', 'Hippocampal ca4': '33.9', 'Hippocampal dentate gyrus': '63.5', 'Lamp5-lhx6 and chandelier': '39.6', 'Lower rhombic lip': '51.0', 'Mammillary body': '43.9', 'Medium spiny neuron': '41.8', 'Mge interneuron': '43.1', 'Midbrain-derived inhibitory': '32.2', 'Miscellaneous': '37.1', 'Splatter': '37.5', 'Thalamic excitatory': '40.5', 'Upper rhombic lip': '76.4', 'Upper-layer intratelencephalic': '51.0', 'Astrocyte': '47.0', 'Bergmann glia': '43.8', 'Central nervous system macrophage': '120.6', 'Choroid plexus epithelial cell': '48.6', 'Committed oligodendrocyte precursor': '74.8', 'Ependymal cell': '58.9', 'Oligodendrocyte': '126.0', 'Oligodendrocyte precursor cell': '79.8', 'Endothelial cell': '95.2', 'Pericyte': '128.2', 'Vascular associated smooth muscle cell': '64.2', 'Fibroblast': '95.6', 'Leukocyte': '55.0', 'Basophil': '54.4', 'Eosinophil': '28.5', 'Neutrophil': '72.0', 'Classical monocyte': '12.3', 'Non-classical monocyte': '18.8', 'Intermediate monocyte': '37.7', 'T-reg': '46.1', 'GdT-cell': '19.0', 'MAIT T-cell': '47.1', 'Memory CD4 T-cell': '25.6', 'Naive CD4 T-cell': '25.0', 'Memory CD8 T-cell': '25.2', 'Naive CD8 T-cell': '17.0', 'Memory B-cell': '46.6', 'Naive B-cell': '39.5', 'Plasmacytoid DC': '80.5', 'Myeloid DC': '52.8', 'NK-cell': '19.2', 'Total PBMC': '44.5', 'Vd2 gdTCR': '40.7', 'Memory CD4 T-cell Th1\\/Th17': '24.1', 'Memory CD4 T-cell Th17': '25.0', 'Memory CD4 T-cell Th2': '25.5', 'Non-Vd2 gdTCR': '47.4', 'Memory CD4 T-cell Th1': '21.8', 'Memory CD4 T-cell TFH': '20.7', 'Terminal effector memory CD4 T-cell': '46.1', 'Central memory CD8 T-cell': '49.3', 'Effector memory CD8 T-cell': '51.7', 'Terminal effector memory CD8 T-cell': '51.8', 'Non-switched memory B-cell': '73.2', 'Plasmablast': '37.4', 'Switched memory B-cell': '72.4', 'Exhausted memory B-cell': '60.5', 'Progenitor cell': '65.8', 'Memory T-reg': '19.8', 'Naive CD4 T-cell activated': '16.7', 'Naive CD8 T-cell activated': '12.1', 'Naive T-reg': '22.9'}
null
{'Adipose Tissue': 9.431014950166112, 'Adrenal Gland': 7.125096899224807, 'Bladder': 10.608285714285714, 'Blood': 4.998763509149623, 'Blood Vessel': 11.487531086142322, 'Brain': 6.6067780847842545, 'Breast': 10.684084967320262, 'Cervix Uteri': 12.674736842105265, 'Colon': 10.200605905006418, 'Esophagus': 13.939683737024222, 'Fallopian Tube': 13.330666666666666, 'Heart': 3.9377188153310105, 'Kidney': 6.1288426966292135, 'Liver': 3.348150442477876, 'Lung': 14.11987197231834, 'Muscle': 6.039047322540473, 'Nerve': 13.861156704361877, 'Ovary': 12.146372222222224, 'Pancreas': 3.732479573170732, 'Pituitary': 10.571583038869257, 'Prostate': 14.106820408163264, 'Salivary Gland': 10.103123456790122, 'Skin': 14.289758430071862, 'Small Intestine': 11.249764705882354, 'Spleen': 12.711033195020748, 'Stomach': 7.44783008356546, 'Testis': 37.17598337950139, 'Thyroid': 13.078012251148545, 'Uterus': 13.399830985915491, 'Vagina': 13.23275}
TRIM13
MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '35.7', 'Basal respiratory cells': '46.2', 'Club cells': '36.4', 'Ionocytes': '45.3', 'Mucus glandular cells': '19.6', 'Serous glandular cells': '21.6', 'Gastric mucus-secreting cells': '13.6', 'Proximal enterocytes': '19.2', 'Paneth cells': '22.6', 'Distal enterocytes': '29.5', 'Intestinal goblet cells': '26.4', 'Exocrine glandular cells': '-0.691', 'Basal prostatic cells': '38.4', 'Prostatic glandular cells': '57.3', 'Breast glandular cells': '0.654', 'Breast myoepithelial cells': '0.557', 'Glandular and luminal cells': '14.3', 'Secretory cells': '25.7', 'Basal keratinocytes': '24.6', 'Suprabasal keratinocytes': '37.3', 'Basal squamous epithelial cells': '21.3', 'Squamous epithelial cells': '30.7', 'Alveolar cells type 1': '0.156', 'Alveolar cells type 2': '0.058', 'Salivary duct cells': '18.9', 'Ductal cells': '0.609', 'Hepatocytes': '0.096', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.335', 'Distal tubular cells': '12.3', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.408', 'Sertoli cells': '-0.535', 'Granulosa cells': '46.9', 'Enteroendocrine cells': '31.8', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '-0.547', 'Excitatory neurons': '29.5', 'Inhibitory neurons': '28.3', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '56.5', 'Bipolar cells': '22.0', 'Horizontal cells': '15.7', 'Astrocytes': '19.8', 'Oligodendrocyte precursor cells': '42.9', 'Oligodendrocytes': '53.5', 'Microglial cells': '34.0', 'Muller glia cells': '13.8', 'Schwann cells': '0.150', 'Spermatogonia': '-0.307', 'Spermatocytes': '0.084', 'Early spermatids': '0.882', 'Late spermatids': '0.649', 'Oocytes': '26.5', 'Cytotrophoblasts': '33.3', 'Syncytiotrophoblasts': '33.7', 'Extravillous trophoblasts': '16.6', 'Endothelial cells': '29.9', 'Lymphatic endothelial cells': '18.0', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '-0.188', 'Smooth muscle cells': '26.6', 'Adipocytes': '31.3', 'Melanocytes': '0.133', 'Fibroblasts': '24.1', 'Peritubular cells': '-0.360', 'Endometrial stromal cells': '23.3', 'Ovarian stromal cells': '27.9', 'Undifferentiated cells': '22.8', 'T-cells': '25.5', 'B-cells': '37.6', 'Plasma cells': '11.7', 'Nk-cells': '26.4', 'Granulocytes': '41.3', 'Monocytes': '32.1', 'Macrophages': '22.1', 'Hofbauer cells': '17.9', 'Kupffer cells': '16.8', 'Dendritic cells': '30.3', 'Langerhans cells': '0.265', 'Erythroid cells': '0.064', 'Adipocytes (Subcutaneous)': '-0.207', 'Adipocytes (Visceral)': '-0.380', 'Breast glandular cells (progenitors)': '0.416', 'Adipocytes (Breast)': '-0.618', 'Colon enterocytes': '0.048', 'Colon enteroendocrine cells': '0.141', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '0.151', 'Mitotic cells (Heart)': '0.485', 'Podocytes': '-0.163', 'Ascending Loop of Henle cells': '0.354', 'Intercalated cells': '-0.112', 'Cholangiocyte': '0.172', 'NK-cells (Liver)': '-0.079', 'Respiratory ciliated cells': '0.210', 'Mitotic cells (Lung)': '-0.007', 'NK-cells (Lung)': '0.157', 'B-cells (Lung)': '0.054', 'Alpha cells': '0.429', 'Beta cells': '0.264', 'Prostate glandular cells': '0.412', 'Prostate basal glandular cells': '0.532', 'Urothelial cells': '0.131', 'Keratinocyte (other)': '0.381', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.340', 'Inner root sheath cells': '-0.257', 'Outer root sheath cells': '-0.142', 'Sebaceous gland cells': '0.001', 'Eccrine sweat gland cells': '-0.215', 'Adipocytes (Skin)': '-0.313', 'Mitotic cells (Skin)': '0.144', 'Parietal cells': '-0.382', 'Chief cells': '-0.347', 'Gastric mucous cells': '-0.142', 'Gastric enteroendocrine cells': '-0.174', 'Mitotic cells (Stomach)': '0.162', 'Parafollicular cells': '-0.014', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '-0.007', 'Adrenal cortex cells': '0.320', 'Adrenal medulla cells': '0.018', 'Mitotic cells (Adrenal gland)': '0.240', 'Minor salivary glandular cells': '0.254', 'Minor salivary gland ductal cells': '0.032', 'Minor salivary gland basal cells': '0.575', 'Mitotic cells (Minor salivary gland)': '0.491', 'Adipocytes (Minor salivary gland)': '0.133', 'Somatotropes': '-0.167', 'Lactotropes': '-0.121', 'Gonadotropes': '-0.119', 'Corticotropes': '0.059', 'Thyrotropes': '0.127', 'Undifferentiated cells (Pituitary gland)': '0.293', 'Mitotic cells (Spleen)': '-0.249', 'Platelets': '-0.180', 'Erythrocytes': '-0.123', 'Hematopoietic stem cells': '-0.320', 'B-cells (Spleen)': '0.551', 'NK-cells (Spleen)': '0.395', 'Amygdala excitatory': '39.5', 'Cerebellar inhibitory': '26.5', 'Cge interneuron': '39.4', 'Deep-layer corticothalamic and 6b': '39.2', 'Deep-layer intratelencephalic': '35.2', 'Deep-layer near-projecting': '36.9', 'Eccentric medium spiny neuron': '41.9', 'Hippocampal ca1-3': '42.3', 'Hippocampal ca4': '33.9', 'Hippocampal dentate gyrus': '63.5', 'Lamp5-lhx6 and chandelier': '39.6', 'Lower rhombic lip': '51.0', 'Mammillary body': '43.9', 'Medium spiny neuron': '41.8', 'Mge interneuron': '43.1', 'Midbrain-derived inhibitory': '32.2', 'Miscellaneous': '37.1', 'Splatter': '37.5', 'Thalamic excitatory': '40.5', 'Upper rhombic lip': '76.4', 'Upper-layer intratelencephalic': '51.0', 'Astrocyte': '47.0', 'Bergmann glia': '43.8', 'Central nervous system macrophage': '120.6', 'Choroid plexus epithelial cell': '48.6', 'Committed oligodendrocyte precursor': '74.8', 'Ependymal cell': '58.9', 'Oligodendrocyte': '126.0', 'Oligodendrocyte precursor cell': '79.8', 'Endothelial cell': '95.2', 'Pericyte': '128.2', 'Vascular associated smooth muscle cell': '64.2', 'Fibroblast': '95.6', 'Leukocyte': '55.0', 'Basophil': '54.4', 'Eosinophil': '28.5', 'Neutrophil': '72.0', 'Classical monocyte': '12.3', 'Non-classical monocyte': '18.8', 'Intermediate monocyte': '37.7', 'T-reg': '46.1', 'GdT-cell': '19.0', 'MAIT T-cell': '47.1', 'Memory CD4 T-cell': '25.6', 'Naive CD4 T-cell': '25.0', 'Memory CD8 T-cell': '25.2', 'Naive CD8 T-cell': '17.0', 'Memory B-cell': '46.6', 'Naive B-cell': '39.5', 'Plasmacytoid DC': '80.5', 'Myeloid DC': '52.8', 'NK-cell': '19.2', 'Total PBMC': '44.5', 'Vd2 gdTCR': '40.7', 'Memory CD4 T-cell Th1\\/Th17': '24.1', 'Memory CD4 T-cell Th17': '25.0', 'Memory CD4 T-cell Th2': '25.5', 'Non-Vd2 gdTCR': '47.4', 'Memory CD4 T-cell Th1': '21.8', 'Memory CD4 T-cell TFH': '20.7', 'Terminal effector memory CD4 T-cell': '46.1', 'Central memory CD8 T-cell': '49.3', 'Effector memory CD8 T-cell': '51.7', 'Terminal effector memory CD8 T-cell': '51.8', 'Non-switched memory B-cell': '73.2', 'Plasmablast': '37.4', 'Switched memory B-cell': '72.4', 'Exhausted memory B-cell': '60.5', 'Progenitor cell': '65.8', 'Memory T-reg': '19.8', 'Naive CD4 T-cell activated': '16.7', 'Naive CD8 T-cell activated': '12.1', 'Naive T-reg': '22.9'}
null
{'Adipose Tissue': 9.431014950166112, 'Adrenal Gland': 7.125096899224807, 'Bladder': 10.608285714285714, 'Blood': 4.998763509149623, 'Blood Vessel': 11.487531086142322, 'Brain': 6.6067780847842545, 'Breast': 10.684084967320262, 'Cervix Uteri': 12.674736842105265, 'Colon': 10.200605905006418, 'Esophagus': 13.939683737024222, 'Fallopian Tube': 13.330666666666666, 'Heart': 3.9377188153310105, 'Kidney': 6.1288426966292135, 'Liver': 3.348150442477876, 'Lung': 14.11987197231834, 'Muscle': 6.039047322540473, 'Nerve': 13.861156704361877, 'Ovary': 12.146372222222224, 'Pancreas': 3.732479573170732, 'Pituitary': 10.571583038869257, 'Prostate': 14.106820408163264, 'Salivary Gland': 10.103123456790122, 'Skin': 14.289758430071862, 'Small Intestine': 11.249764705882354, 'Spleen': 12.711033195020748, 'Stomach': 7.44783008356546, 'Testis': 37.17598337950139, 'Thyroid': 13.078012251148545, 'Uterus': 13.399830985915491, 'Vagina': 13.23275}
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RING finger
null
null
null
VCP,AKT1,MDM2,SQSTM1, TRAF6,IKBKG
MDM2, AKT1, TRAF6, IKBKG
29
null
null
null
null
79.775479
0.523071
79.775479
0.523071
1,949
O60858
P04234
17314412
UbiNet, UbiBrowser
TRIM13
MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '35.7', 'Basal respiratory cells': '46.2', 'Club cells': '36.4', 'Ionocytes': '45.3', 'Mucus glandular cells': '19.6', 'Serous glandular cells': '21.6', 'Gastric mucus-secreting cells': '13.6', 'Proximal enterocytes': '19.2', 'Paneth cells': '22.6', 'Distal enterocytes': '29.5', 'Intestinal goblet cells': '26.4', 'Exocrine glandular cells': '-0.691', 'Basal prostatic cells': '38.4', 'Prostatic glandular cells': '57.3', 'Breast glandular cells': '0.654', 'Breast myoepithelial cells': '0.557', 'Glandular and luminal cells': '14.3', 'Secretory cells': '25.7', 'Basal keratinocytes': '24.6', 'Suprabasal keratinocytes': '37.3', 'Basal squamous epithelial cells': '21.3', 'Squamous epithelial cells': '30.7', 'Alveolar cells type 1': '0.156', 'Alveolar cells type 2': '0.058', 'Salivary duct cells': '18.9', 'Ductal cells': '0.609', 'Hepatocytes': '0.096', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.335', 'Distal tubular cells': '12.3', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.408', 'Sertoli cells': '-0.535', 'Granulosa cells': '46.9', 'Enteroendocrine cells': '31.8', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '-0.547', 'Excitatory neurons': '29.5', 'Inhibitory neurons': '28.3', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '56.5', 'Bipolar cells': '22.0', 'Horizontal cells': '15.7', 'Astrocytes': '19.8', 'Oligodendrocyte precursor cells': '42.9', 'Oligodendrocytes': '53.5', 'Microglial cells': '34.0', 'Muller glia cells': '13.8', 'Schwann cells': '0.150', 'Spermatogonia': '-0.307', 'Spermatocytes': '0.084', 'Early spermatids': '0.882', 'Late spermatids': '0.649', 'Oocytes': '26.5', 'Cytotrophoblasts': '33.3', 'Syncytiotrophoblasts': '33.7', 'Extravillous trophoblasts': '16.6', 'Endothelial cells': '29.9', 'Lymphatic endothelial cells': '18.0', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '-0.188', 'Smooth muscle cells': '26.6', 'Adipocytes': '31.3', 'Melanocytes': '0.133', 'Fibroblasts': '24.1', 'Peritubular cells': '-0.360', 'Endometrial stromal cells': '23.3', 'Ovarian stromal cells': '27.9', 'Undifferentiated cells': '22.8', 'T-cells': '25.5', 'B-cells': '37.6', 'Plasma cells': '11.7', 'Nk-cells': '26.4', 'Granulocytes': '41.3', 'Monocytes': '32.1', 'Macrophages': '22.1', 'Hofbauer cells': '17.9', 'Kupffer cells': '16.8', 'Dendritic cells': '30.3', 'Langerhans cells': '0.265', 'Erythroid cells': '0.064', 'Adipocytes (Subcutaneous)': '-0.207', 'Adipocytes (Visceral)': '-0.380', 'Breast glandular cells (progenitors)': '0.416', 'Adipocytes (Breast)': '-0.618', 'Colon enterocytes': '0.048', 'Colon enteroendocrine cells': '0.141', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '0.151', 'Mitotic cells (Heart)': '0.485', 'Podocytes': '-0.163', 'Ascending Loop of Henle cells': '0.354', 'Intercalated cells': '-0.112', 'Cholangiocyte': '0.172', 'NK-cells (Liver)': '-0.079', 'Respiratory ciliated cells': '0.210', 'Mitotic cells (Lung)': '-0.007', 'NK-cells (Lung)': '0.157', 'B-cells (Lung)': '0.054', 'Alpha cells': '0.429', 'Beta cells': '0.264', 'Prostate glandular cells': '0.412', 'Prostate basal glandular cells': '0.532', 'Urothelial cells': '0.131', 'Keratinocyte (other)': '0.381', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.340', 'Inner root sheath cells': '-0.257', 'Outer root sheath cells': '-0.142', 'Sebaceous gland cells': '0.001', 'Eccrine sweat gland cells': '-0.215', 'Adipocytes (Skin)': '-0.313', 'Mitotic cells (Skin)': '0.144', 'Parietal cells': '-0.382', 'Chief cells': '-0.347', 'Gastric mucous cells': '-0.142', 'Gastric enteroendocrine cells': '-0.174', 'Mitotic cells (Stomach)': '0.162', 'Parafollicular cells': '-0.014', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '-0.007', 'Adrenal cortex cells': '0.320', 'Adrenal medulla cells': '0.018', 'Mitotic cells (Adrenal gland)': '0.240', 'Minor salivary glandular cells': '0.254', 'Minor salivary gland ductal cells': '0.032', 'Minor salivary gland basal cells': '0.575', 'Mitotic cells (Minor salivary gland)': '0.491', 'Adipocytes (Minor salivary gland)': '0.133', 'Somatotropes': '-0.167', 'Lactotropes': '-0.121', 'Gonadotropes': '-0.119', 'Corticotropes': '0.059', 'Thyrotropes': '0.127', 'Undifferentiated cells (Pituitary gland)': '0.293', 'Mitotic cells (Spleen)': '-0.249', 'Platelets': '-0.180', 'Erythrocytes': '-0.123', 'Hematopoietic stem cells': '-0.320', 'B-cells (Spleen)': '0.551', 'NK-cells (Spleen)': '0.395', 'Amygdala excitatory': '39.5', 'Cerebellar inhibitory': '26.5', 'Cge interneuron': '39.4', 'Deep-layer corticothalamic and 6b': '39.2', 'Deep-layer intratelencephalic': '35.2', 'Deep-layer near-projecting': '36.9', 'Eccentric medium spiny neuron': '41.9', 'Hippocampal ca1-3': '42.3', 'Hippocampal ca4': '33.9', 'Hippocampal dentate gyrus': '63.5', 'Lamp5-lhx6 and chandelier': '39.6', 'Lower rhombic lip': '51.0', 'Mammillary body': '43.9', 'Medium spiny neuron': '41.8', 'Mge interneuron': '43.1', 'Midbrain-derived inhibitory': '32.2', 'Miscellaneous': '37.1', 'Splatter': '37.5', 'Thalamic excitatory': '40.5', 'Upper rhombic lip': '76.4', 'Upper-layer intratelencephalic': '51.0', 'Astrocyte': '47.0', 'Bergmann glia': '43.8', 'Central nervous system macrophage': '120.6', 'Choroid plexus epithelial cell': '48.6', 'Committed oligodendrocyte precursor': '74.8', 'Ependymal cell': '58.9', 'Oligodendrocyte': '126.0', 'Oligodendrocyte precursor cell': '79.8', 'Endothelial cell': '95.2', 'Pericyte': '128.2', 'Vascular associated smooth muscle cell': '64.2', 'Fibroblast': '95.6', 'Leukocyte': '55.0', 'Basophil': '54.4', 'Eosinophil': '28.5', 'Neutrophil': '72.0', 'Classical monocyte': '12.3', 'Non-classical monocyte': '18.8', 'Intermediate monocyte': '37.7', 'T-reg': '46.1', 'GdT-cell': '19.0', 'MAIT T-cell': '47.1', 'Memory CD4 T-cell': '25.6', 'Naive CD4 T-cell': '25.0', 'Memory CD8 T-cell': '25.2', 'Naive CD8 T-cell': '17.0', 'Memory B-cell': '46.6', 'Naive B-cell': '39.5', 'Plasmacytoid DC': '80.5', 'Myeloid DC': '52.8', 'NK-cell': '19.2', 'Total PBMC': '44.5', 'Vd2 gdTCR': '40.7', 'Memory CD4 T-cell Th1\\/Th17': '24.1', 'Memory CD4 T-cell Th17': '25.0', 'Memory CD4 T-cell Th2': '25.5', 'Non-Vd2 gdTCR': '47.4', 'Memory CD4 T-cell Th1': '21.8', 'Memory CD4 T-cell TFH': '20.7', 'Terminal effector memory CD4 T-cell': '46.1', 'Central memory CD8 T-cell': '49.3', 'Effector memory CD8 T-cell': '51.7', 'Terminal effector memory CD8 T-cell': '51.8', 'Non-switched memory B-cell': '73.2', 'Plasmablast': '37.4', 'Switched memory B-cell': '72.4', 'Exhausted memory B-cell': '60.5', 'Progenitor cell': '65.8', 'Memory T-reg': '19.8', 'Naive CD4 T-cell activated': '16.7', 'Naive CD8 T-cell activated': '12.1', 'Naive T-reg': '22.9'}
null
{'Adipose Tissue': 9.431014950166112, 'Adrenal Gland': 7.125096899224807, 'Bladder': 10.608285714285714, 'Blood': 4.998763509149623, 'Blood Vessel': 11.487531086142322, 'Brain': 6.6067780847842545, 'Breast': 10.684084967320262, 'Cervix Uteri': 12.674736842105265, 'Colon': 10.200605905006418, 'Esophagus': 13.939683737024222, 'Fallopian Tube': 13.330666666666666, 'Heart': 3.9377188153310105, 'Kidney': 6.1288426966292135, 'Liver': 3.348150442477876, 'Lung': 14.11987197231834, 'Muscle': 6.039047322540473, 'Nerve': 13.861156704361877, 'Ovary': 12.146372222222224, 'Pancreas': 3.732479573170732, 'Pituitary': 10.571583038869257, 'Prostate': 14.106820408163264, 'Salivary Gland': 10.103123456790122, 'Skin': 14.289758430071862, 'Small Intestine': 11.249764705882354, 'Spleen': 12.711033195020748, 'Stomach': 7.44783008356546, 'Testis': 37.17598337950139, 'Thyroid': 13.078012251148545, 'Uterus': 13.399830985915491, 'Vagina': 13.23275}
CD3D
MEHSTFLSGLVLATLLSQVSPFKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDLGKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGIIVTDVIATLLLALGVFCFAGHETGRLSGAADTQALLRNDQVYQPLRDRDDAQYSHLGGNWARNK
Homo sapiens
Cell membrane
Tissue enriched (lymphoid)
{'Ciliated cells': '1.1', 'Basal respiratory cells': '0.0', 'Club cells': '1.7', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.8', 'Serous glandular cells': '14.2', 'Gastric mucus-secreting cells': '7.7', 'Proximal enterocytes': '0.1', 'Paneth cells': '0.2', 'Distal enterocytes': '0.1', 'Intestinal goblet cells': '0.7', 'Exocrine glandular cells': '-0.280', 'Basal prostatic cells': '7.5', 'Prostatic glandular cells': '4.0', 'Breast glandular cells': '0.474', 'Breast myoepithelial cells': '0.504', 'Glandular and luminal cells': '0.9', 'Secretory cells': '1.0', 'Basal keratinocytes': '8.4', 'Suprabasal keratinocytes': '3.4', 'Basal squamous epithelial cells': '1.1', 'Squamous epithelial cells': '1.3', 'Alveolar cells type 1': '0.030', 'Alveolar cells type 2': '-0.096', 'Salivary duct cells': '0.7', 'Ductal cells': '0.330', 'Hepatocytes': '0.186', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.195', 'Distal tubular cells': '0.0', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.292', 'Sertoli cells': '-0.005', 'Granulosa cells': '0.5', 'Enteroendocrine cells': '0.3', 'Pancreatic endocrine cells': '13.6', 'Leydig cells': '0.120', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.2', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.9', 'Muller glia cells': '0.0', 'Schwann cells': '0.128', 'Spermatogonia': '0.274', 'Spermatocytes': '0.018', 'Early spermatids': '-0.067', 'Late spermatids': '-0.132', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.3', 'Syncytiotrophoblasts': '0.2', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '4.7', 'Lymphatic endothelial cells': '0.2', 'Cardiomyocytes': '0.300', 'Skeletal myocytes': '0.294', 'Smooth muscle cells': '4.1', 'Adipocytes': '4.2', 'Melanocytes': '0.177', 'Fibroblasts': '4.4', 'Peritubular cells': '0.226', 'Endometrial stromal cells': '0.6', 'Ovarian stromal cells': '0.6', 'Undifferentiated cells': '0.3', 'T-cells': '663.2', 'B-cells': '10.3', 'Plasma cells': '18.3', 'Nk-cells': '102.9', 'Granulocytes': '8.1', 'Monocytes': '14.3', 'Macrophages': '10.1', 'Hofbauer cells': '0.4', 'Kupffer cells': '12.1', 'Dendritic cells': '24.9', 'Langerhans cells': '0.558', 'Erythroid cells': '0.023', 'Adipocytes (Subcutaneous)': '-0.239', 'Adipocytes (Visceral)': '-0.273', 'Breast glandular cells (progenitors)': '0.374', 'Adipocytes (Breast)': '-0.576', 'Colon enterocytes': '0.319', 'Colon enteroendocrine cells': '0.053', 'Enteric glia cells': '-0.129', 'Mitotic cells (Colon)': '0.356', 'Mitotic cells (Heart)': '0.369', 'Podocytes': '-0.113', 'Ascending Loop of Henle cells': '0.154', 'Intercalated cells': '-0.046', 'Cholangiocyte': '0.212', 'NK-cells (Liver)': '0.124', 'Respiratory ciliated cells': '0.016', 'Mitotic cells (Lung)': '0.018', 'NK-cells (Lung)': '0.360', 'B-cells (Lung)': '0.457', 'Alpha cells': '0.241', 'Beta cells': '0.087', 'Prostate glandular cells': '-0.153', 'Prostate basal glandular cells': '0.292', 'Urothelial cells': '0.364', 'Keratinocyte (other)': '-0.010', 'Keratinocyte (granular)': '0.016', 'Hair cortex cells': '-0.031', 'Inner root sheath cells': '-0.069', 'Outer root sheath cells': '0.043', 'Sebaceous gland cells': '0.253', 'Eccrine sweat gland cells': '-0.006', 'Adipocytes (Skin)': '0.127', 'Mitotic cells (Skin)': '0.070', 'Parietal cells': '0.493', 'Chief cells': '0.388', 'Gastric mucous cells': '0.701', 'Gastric enteroendocrine cells': '0.486', 'Mitotic cells (Stomach)': '0.418', 'Parafollicular cells': '0.002', 'Thyroid glandular cells': '-0.090', 'Mitotic cells (Thyroid)': '0.379', 'Adrenal cortex cells': '0.111', 'Adrenal medulla cells': '0.231', 'Mitotic cells (Adrenal gland)': '0.137', 'Minor salivary glandular cells': '0.231', 'Minor salivary gland ductal cells': '0.179', 'Minor salivary gland basal cells': '0.045', 'Mitotic cells (Minor salivary gland)': '0.147', 'Adipocytes (Minor salivary gland)': '0.290', 'Somatotropes': '-0.325', 'Lactotropes': '-0.246', 'Gonadotropes': '0.036', 'Corticotropes': '-0.191', 'Thyrotropes': '0.084', 'Undifferentiated cells (Pituitary gland)': '0.425', 'Mitotic cells (Spleen)': '-0.217', 'Platelets': '-0.039', 'Erythrocytes': '-0.154', 'Hematopoietic stem cells': '-0.130', 'B-cells (Spleen)': '0.362', 'NK-cells (Spleen)': '0.258', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.0', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.0', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '0.1', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.1', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.1', 'Oligodendrocyte': '0.0', 'Oligodendrocyte precursor cell': '0.1', 'Endothelial cell': '0.3', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.1', 'Leukocyte': '121.3', 'Basophil': '0.6', 'Eosinophil': '4.6', 'Neutrophil': '0.0', 'Classical monocyte': '0.8', 'Non-classical monocyte': '0.7', 'Intermediate monocyte': '1.6', 'T-reg': '479.4', 'GdT-cell': '1434.7', 'MAIT T-cell': '455.5', 'Memory CD4 T-cell': '1184.7', 'Naive CD4 T-cell': '951.1', 'Memory CD8 T-cell': '1338.7', 'Naive CD8 T-cell': '947.2', 'Memory B-cell': '9.6', 'Naive B-cell': '0.1', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.3', 'NK-cell': '41.9', 'Total PBMC': '222.3', 'Vd2 gdTCR': '786.9', 'Memory CD4 T-cell Th1\\/Th17': '795.1', 'Memory CD4 T-cell Th17': '1011.9', 'Memory CD4 T-cell Th2': '966.3', 'Non-Vd2 gdTCR': '661.7', 'Memory CD4 T-cell Th1': '970.4', 'Memory CD4 T-cell TFH': '1059.5', 'Terminal effector memory CD4 T-cell': '432.6', 'Central memory CD8 T-cell': '417.1', 'Effector memory CD8 T-cell': '402.7', 'Terminal effector memory CD8 T-cell': '816.4', 'Non-switched memory B-cell': '0.8', 'Plasmablast': '1.1', 'Switched memory B-cell': '2.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.1', 'Memory T-reg': '1214.5', 'Naive CD4 T-cell activated': '1178.0', 'Naive CD8 T-cell activated': '1770.6', 'Naive T-reg': '870.7'}
1XIW, 6JXR, 7FJD, 7FJE, 7FJF, 7PHR, 8ES7, 8ES8, 8ES9, 8JC0, 8JCB, 8WXE, 8WY0, 8WYI, 8YC0
{'Adipose Tissue': 4.044812317275747, 'Adrenal Gland': 0.9931468604651164, 'Bladder': 5.7352428571428575, 'Blood': 39.8575873196986, 'Blood Vessel': 2.4127460749063667, 'Brain': 0.3042616010598031, 'Breast': 3.3336257734204793, 'Cervix Uteri': 3.2162157894736843, 'Colon': 4.684412387676509, 'Esophagus': 2.526717979238754, 'Fallopian Tube': 4.492222222222222, 'Heart': 0.5594157723577236, 'Kidney': 2.6296475280898877, 'Liver': 1.4144593362831857, 'Lung': 14.564619723183393, 'Muscle': 0.3625767621419676, 'Nerve': 1.9599861066235864, 'Ovary': 1.061336, 'Pancreas': 0.6302717987804878, 'Pituitary': 1.257713215547703, 'Prostate': 4.664183265306122, 'Salivary Gland': 3.2403277777777775, 'Skin': 1.3800606578220012, 'Small Intestine': 41.91844064171123, 'Spleen': 56.491091286307054, 'Stomach': 5.276620055710306, 'Testis': 0.9189831024930748, 'Thyroid': 6.430456814701379, 'Uterus': 2.106361267605634, 'Vagina': 5.763717948717948}
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[40.14, 52.53, 52.7, 62.19, 62.95, 61.47, 61.97, 60.75, 61.71, 62.3, 62.49, 60.93, 60.92, 60.43, 56.83, 52.37, 54.86, 58.62, 69.23, 74.03, 80.13, 85.22, 88.25, 90.98, 91.58, 92.94, 92.19, 91.77, 90.83, 89.33, 91.31, 92.7, 94.82, 94.02, 93.58, 92.22, 89.21, 85.69, 85.62, 87.31, 89.53, 90.1, 91.94, 91.38, 93.38, 93.12, 91.88, 90.73, 89.0, 90.76, 89.26, 81.08, 65.33, 70.02, 74.14, 86.34, 90.94, 93.08, 93.87, 94.92, 92.93, 92.94, 91.26, 89.9, 91.51, 91.8, 93.7, 95.15, 94.97, 94.57, 92.83, 92.28, 91.3, 89.24, 84.05, 85.21, 82.81, 79.82, 78.92, 77.7, 80.85, 87.05, 88.74, 90.27, 91.65, 92.65, 93.98, 94.13, 94.04, 92.44, 90.72, 87.83, 80.58, 73.64, 71.54, 82.3, 83.91, 82.75, 87.07, 91.96, 94.58, 93.35, 94.05, 95.78, 95.25, 95.38, 95.88, 97.27, 97.69, 97.59, 98.12, 98.18, 97.99, 98.04, 97.59, 97.53, 97.43, 97.02, 96.27, 95.2, 94.19, 94.42, 92.42, 89.1, 86.03, 84.35, 71.56, 64.66, 59.75, 52.21, 47.7, 49.14, 44.93, 47.66, 46.48, 49.41, 53.96, 52.91, 55.74, 58.63, 59.74, 56.44, 59.59, 61.15, 60.59, 56.63, 58.91, 60.74, 52.0, 60.87, 58.83, 58.21, 54.6, 52.56, 52.5, 49.36, 56.2, 57.28, 56.68, 56.72, 57.26, 58.2, 60.5, 61.1, 54.92, 56.86, 58.0, 59.06, 57.91, 60.88, 51.57]
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RING finger
null
null
null
VCP,AKT1,MDM2,SQSTM1, TRAF6,IKBKG
MDM2, AKT1, TRAF6, IKBKG
29
null
null
null
null
79.775479
0.523071
77.556784
0.575146
2,831
O60858
P22736
30224829
UbiBrowser
TRIM13
MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '35.7', 'Basal respiratory cells': '46.2', 'Club cells': '36.4', 'Ionocytes': '45.3', 'Mucus glandular cells': '19.6', 'Serous glandular cells': '21.6', 'Gastric mucus-secreting cells': '13.6', 'Proximal enterocytes': '19.2', 'Paneth cells': '22.6', 'Distal enterocytes': '29.5', 'Intestinal goblet cells': '26.4', 'Exocrine glandular cells': '-0.691', 'Basal prostatic cells': '38.4', 'Prostatic glandular cells': '57.3', 'Breast glandular cells': '0.654', 'Breast myoepithelial cells': '0.557', 'Glandular and luminal cells': '14.3', 'Secretory cells': '25.7', 'Basal keratinocytes': '24.6', 'Suprabasal keratinocytes': '37.3', 'Basal squamous epithelial cells': '21.3', 'Squamous epithelial cells': '30.7', 'Alveolar cells type 1': '0.156', 'Alveolar cells type 2': '0.058', 'Salivary duct cells': '18.9', 'Ductal cells': '0.609', 'Hepatocytes': '0.096', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.335', 'Distal tubular cells': '12.3', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.408', 'Sertoli cells': '-0.535', 'Granulosa cells': '46.9', 'Enteroendocrine cells': '31.8', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '-0.547', 'Excitatory neurons': '29.5', 'Inhibitory neurons': '28.3', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '56.5', 'Bipolar cells': '22.0', 'Horizontal cells': '15.7', 'Astrocytes': '19.8', 'Oligodendrocyte precursor cells': '42.9', 'Oligodendrocytes': '53.5', 'Microglial cells': '34.0', 'Muller glia cells': '13.8', 'Schwann cells': '0.150', 'Spermatogonia': '-0.307', 'Spermatocytes': '0.084', 'Early spermatids': '0.882', 'Late spermatids': '0.649', 'Oocytes': '26.5', 'Cytotrophoblasts': '33.3', 'Syncytiotrophoblasts': '33.7', 'Extravillous trophoblasts': '16.6', 'Endothelial cells': '29.9', 'Lymphatic endothelial cells': '18.0', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '-0.188', 'Smooth muscle cells': '26.6', 'Adipocytes': '31.3', 'Melanocytes': '0.133', 'Fibroblasts': '24.1', 'Peritubular cells': '-0.360', 'Endometrial stromal cells': '23.3', 'Ovarian stromal cells': '27.9', 'Undifferentiated cells': '22.8', 'T-cells': '25.5', 'B-cells': '37.6', 'Plasma cells': '11.7', 'Nk-cells': '26.4', 'Granulocytes': '41.3', 'Monocytes': '32.1', 'Macrophages': '22.1', 'Hofbauer cells': '17.9', 'Kupffer cells': '16.8', 'Dendritic cells': '30.3', 'Langerhans cells': '0.265', 'Erythroid cells': '0.064', 'Adipocytes (Subcutaneous)': '-0.207', 'Adipocytes (Visceral)': '-0.380', 'Breast glandular cells (progenitors)': '0.416', 'Adipocytes (Breast)': '-0.618', 'Colon enterocytes': '0.048', 'Colon enteroendocrine cells': '0.141', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '0.151', 'Mitotic cells (Heart)': '0.485', 'Podocytes': '-0.163', 'Ascending Loop of Henle cells': '0.354', 'Intercalated cells': '-0.112', 'Cholangiocyte': '0.172', 'NK-cells (Liver)': '-0.079', 'Respiratory ciliated cells': '0.210', 'Mitotic cells (Lung)': '-0.007', 'NK-cells (Lung)': '0.157', 'B-cells (Lung)': '0.054', 'Alpha cells': '0.429', 'Beta cells': '0.264', 'Prostate glandular cells': '0.412', 'Prostate basal glandular cells': '0.532', 'Urothelial cells': '0.131', 'Keratinocyte (other)': '0.381', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.340', 'Inner root sheath cells': '-0.257', 'Outer root sheath cells': '-0.142', 'Sebaceous gland cells': '0.001', 'Eccrine sweat gland cells': '-0.215', 'Adipocytes (Skin)': '-0.313', 'Mitotic cells (Skin)': '0.144', 'Parietal cells': '-0.382', 'Chief cells': '-0.347', 'Gastric mucous cells': '-0.142', 'Gastric enteroendocrine cells': '-0.174', 'Mitotic cells (Stomach)': '0.162', 'Parafollicular cells': '-0.014', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '-0.007', 'Adrenal cortex cells': '0.320', 'Adrenal medulla cells': '0.018', 'Mitotic cells (Adrenal gland)': '0.240', 'Minor salivary glandular cells': '0.254', 'Minor salivary gland ductal cells': '0.032', 'Minor salivary gland basal cells': '0.575', 'Mitotic cells (Minor salivary gland)': '0.491', 'Adipocytes (Minor salivary gland)': '0.133', 'Somatotropes': '-0.167', 'Lactotropes': '-0.121', 'Gonadotropes': '-0.119', 'Corticotropes': '0.059', 'Thyrotropes': '0.127', 'Undifferentiated cells (Pituitary gland)': '0.293', 'Mitotic cells (Spleen)': '-0.249', 'Platelets': '-0.180', 'Erythrocytes': '-0.123', 'Hematopoietic stem cells': '-0.320', 'B-cells (Spleen)': '0.551', 'NK-cells (Spleen)': '0.395', 'Amygdala excitatory': '39.5', 'Cerebellar inhibitory': '26.5', 'Cge interneuron': '39.4', 'Deep-layer corticothalamic and 6b': '39.2', 'Deep-layer intratelencephalic': '35.2', 'Deep-layer near-projecting': '36.9', 'Eccentric medium spiny neuron': '41.9', 'Hippocampal ca1-3': '42.3', 'Hippocampal ca4': '33.9', 'Hippocampal dentate gyrus': '63.5', 'Lamp5-lhx6 and chandelier': '39.6', 'Lower rhombic lip': '51.0', 'Mammillary body': '43.9', 'Medium spiny neuron': '41.8', 'Mge interneuron': '43.1', 'Midbrain-derived inhibitory': '32.2', 'Miscellaneous': '37.1', 'Splatter': '37.5', 'Thalamic excitatory': '40.5', 'Upper rhombic lip': '76.4', 'Upper-layer intratelencephalic': '51.0', 'Astrocyte': '47.0', 'Bergmann glia': '43.8', 'Central nervous system macrophage': '120.6', 'Choroid plexus epithelial cell': '48.6', 'Committed oligodendrocyte precursor': '74.8', 'Ependymal cell': '58.9', 'Oligodendrocyte': '126.0', 'Oligodendrocyte precursor cell': '79.8', 'Endothelial cell': '95.2', 'Pericyte': '128.2', 'Vascular associated smooth muscle cell': '64.2', 'Fibroblast': '95.6', 'Leukocyte': '55.0', 'Basophil': '54.4', 'Eosinophil': '28.5', 'Neutrophil': '72.0', 'Classical monocyte': '12.3', 'Non-classical monocyte': '18.8', 'Intermediate monocyte': '37.7', 'T-reg': '46.1', 'GdT-cell': '19.0', 'MAIT T-cell': '47.1', 'Memory CD4 T-cell': '25.6', 'Naive CD4 T-cell': '25.0', 'Memory CD8 T-cell': '25.2', 'Naive CD8 T-cell': '17.0', 'Memory B-cell': '46.6', 'Naive B-cell': '39.5', 'Plasmacytoid DC': '80.5', 'Myeloid DC': '52.8', 'NK-cell': '19.2', 'Total PBMC': '44.5', 'Vd2 gdTCR': '40.7', 'Memory CD4 T-cell Th1\\/Th17': '24.1', 'Memory CD4 T-cell Th17': '25.0', 'Memory CD4 T-cell Th2': '25.5', 'Non-Vd2 gdTCR': '47.4', 'Memory CD4 T-cell Th1': '21.8', 'Memory CD4 T-cell TFH': '20.7', 'Terminal effector memory CD4 T-cell': '46.1', 'Central memory CD8 T-cell': '49.3', 'Effector memory CD8 T-cell': '51.7', 'Terminal effector memory CD8 T-cell': '51.8', 'Non-switched memory B-cell': '73.2', 'Plasmablast': '37.4', 'Switched memory B-cell': '72.4', 'Exhausted memory B-cell': '60.5', 'Progenitor cell': '65.8', 'Memory T-reg': '19.8', 'Naive CD4 T-cell activated': '16.7', 'Naive CD8 T-cell activated': '12.1', 'Naive T-reg': '22.9'}
null
{'Adipose Tissue': 9.431014950166112, 'Adrenal Gland': 7.125096899224807, 'Bladder': 10.608285714285714, 'Blood': 4.998763509149623, 'Blood Vessel': 11.487531086142322, 'Brain': 6.6067780847842545, 'Breast': 10.684084967320262, 'Cervix Uteri': 12.674736842105265, 'Colon': 10.200605905006418, 'Esophagus': 13.939683737024222, 'Fallopian Tube': 13.330666666666666, 'Heart': 3.9377188153310105, 'Kidney': 6.1288426966292135, 'Liver': 3.348150442477876, 'Lung': 14.11987197231834, 'Muscle': 6.039047322540473, 'Nerve': 13.861156704361877, 'Ovary': 12.146372222222224, 'Pancreas': 3.732479573170732, 'Pituitary': 10.571583038869257, 'Prostate': 14.106820408163264, 'Salivary Gland': 10.103123456790122, 'Skin': 14.289758430071862, 'Small Intestine': 11.249764705882354, 'Spleen': 12.711033195020748, 'Stomach': 7.44783008356546, 'Testis': 37.17598337950139, 'Thyroid': 13.078012251148545, 'Uterus': 13.399830985915491, 'Vagina': 13.23275}
NR4A1
MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASPEAAPAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQEPRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF
Homo sapiens
Nucleus, Cytoplasm, cytosol, Mitochondrion
Low tissue specificity
{'Ciliated cells': '200.8', 'Basal respiratory cells': '203.9', 'Club cells': '326.9', 'Ionocytes': '451.7', 'Mucus glandular cells': '410.5', 'Serous glandular cells': '342.1', 'Gastric mucus-secreting cells': '394.4', 'Proximal enterocytes': '60.8', 'Paneth cells': '301.2', 'Distal enterocytes': '186.2', 'Intestinal goblet cells': '479.6', 'Exocrine glandular cells': '0.077', 'Basal prostatic cells': '623.7', 'Prostatic glandular cells': '257.1', 'Breast glandular cells': '0.157', 'Breast myoepithelial cells': '0.354', 'Glandular and luminal cells': '732.3', 'Secretory cells': '462.3', 'Basal keratinocytes': '328.9', 'Suprabasal keratinocytes': '303.6', 'Basal squamous epithelial cells': '431.0', 'Squamous epithelial cells': '161.5', 'Alveolar cells type 1': '0.232', 'Alveolar cells type 2': '-0.104', 'Salivary duct cells': '389.0', 'Ductal cells': '0.061', 'Hepatocytes': '0.178', 'Cholangiocytes': '72.5', 'Proximal tubular cells': '0.104', 'Distal tubular cells': '12.3', 'Collecting duct cells': '75.8', 'Mesothelial cells': '0.103', 'Sertoli cells': '0.162', 'Granulosa cells': '495.7', 'Enteroendocrine cells': '334.2', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '0.366', 'Excitatory neurons': '16.8', 'Inhibitory neurons': '5.6', 'Cone photoreceptor cells': '32.3', 'Rod photoreceptor cells': '100.0', 'Bipolar cells': '32.3', 'Horizontal cells': '40.3', 'Astrocytes': '4.0', 'Oligodendrocyte precursor cells': '6.1', 'Oligodendrocytes': '1.2', 'Microglial cells': '8.1', 'Muller glia cells': '113.2', 'Schwann cells': '0.057', 'Spermatogonia': '0.155', 'Spermatocytes': '-0.193', 'Early spermatids': '-0.371', 'Late spermatids': '-0.341', 'Oocytes': '72.1', 'Cytotrophoblasts': '63.1', 'Syncytiotrophoblasts': '92.3', 'Extravillous trophoblasts': '29.7', 'Endothelial cells': '279.8', 'Lymphatic endothelial cells': '197.9', 'Cardiomyocytes': '0.036', 'Skeletal myocytes': '0.380', 'Smooth muscle cells': '579.5', 'Adipocytes': '317.2', 'Melanocytes': '-0.118', 'Fibroblasts': '423.1', 'Peritubular cells': '0.448', 'Endometrial stromal cells': '175.2', 'Ovarian stromal cells': '1000.6', 'Undifferentiated cells': '203.3', 'T-cells': '144.8', 'B-cells': '260.3', 'Plasma cells': '248.1', 'Nk-cells': '56.2', 'Granulocytes': '650.1', 'Monocytes': '868.3', 'Macrophages': '358.4', 'Hofbauer cells': '123.0', 'Kupffer cells': '88.8', 'Dendritic cells': '206.3', 'Langerhans cells': '-0.145', 'Erythroid cells': '0.220', 'Adipocytes (Subcutaneous)': '-0.466', 'Adipocytes (Visceral)': '0.019', 'Breast glandular cells (progenitors)': '0.108', 'Adipocytes (Breast)': '-0.262', 'Colon enterocytes': '-0.051', 'Colon enteroendocrine cells': '0.108', 'Enteric glia cells': '0.050', 'Mitotic cells (Colon)': '-0.031', 'Mitotic cells (Heart)': '0.057', 'Podocytes': '0.217', 'Ascending Loop of Henle cells': '0.350', 'Intercalated cells': '0.359', 'Cholangiocyte': '0.206', 'NK-cells (Liver)': '0.166', 'Respiratory ciliated cells': '0.108', 'Mitotic cells (Lung)': '-0.228', 'NK-cells (Lung)': '0.234', 'B-cells (Lung)': '0.182', 'Alpha cells': '0.086', 'Beta cells': '-0.005', 'Prostate glandular cells': '0.086', 'Prostate basal glandular cells': '-0.116', 'Urothelial cells': '-0.015', 'Keratinocyte (other)': '-0.157', 'Keratinocyte (granular)': '-0.246', 'Hair cortex cells': '0.187', 'Inner root sheath cells': '0.193', 'Outer root sheath cells': '0.279', 'Sebaceous gland cells': '-0.046', 'Eccrine sweat gland cells': '0.324', 'Adipocytes (Skin)': '0.048', 'Mitotic cells (Skin)': '-0.002', 'Parietal cells': '-0.475', 'Chief cells': '-0.388', 'Gastric mucous cells': '-0.479', 'Gastric enteroendocrine cells': '-0.343', 'Mitotic cells (Stomach)': '-0.288', 'Parafollicular cells': '0.034', 'Thyroid glandular cells': '0.147', 'Mitotic cells (Thyroid)': '0.024', 'Adrenal cortex cells': '0.290', 'Adrenal medulla cells': '-0.028', 'Mitotic cells (Adrenal gland)': '-0.378', 'Minor salivary glandular cells': '0.350', 'Minor salivary gland ductal cells': '0.188', 'Minor salivary gland basal cells': '-0.166', 'Mitotic cells (Minor salivary gland)': '-0.319', 'Adipocytes (Minor salivary gland)': '0.001', 'Somatotropes': '-0.290', 'Lactotropes': '-0.065', 'Gonadotropes': '0.303', 'Corticotropes': '-0.032', 'Thyrotropes': '0.158', 'Undifferentiated cells (Pituitary gland)': '0.159', 'Mitotic cells (Spleen)': '-0.196', 'Platelets': '-0.200', 'Erythrocytes': '-0.030', 'Hematopoietic stem cells': '-0.175', 'B-cells (Spleen)': '0.246', 'NK-cells (Spleen)': '0.154', 'Amygdala excitatory': '12.5', 'Cerebellar inhibitory': '5.8', 'Cge interneuron': '7.0', 'Deep-layer corticothalamic and 6b': '19.8', 'Deep-layer intratelencephalic': '22.0', 'Deep-layer near-projecting': '10.7', 'Eccentric medium spiny neuron': '12.2', 'Hippocampal ca1-3': '18.5', 'Hippocampal ca4': '5.9', 'Hippocampal dentate gyrus': '2.0', 'Lamp5-lhx6 and chandelier': '7.7', 'Lower rhombic lip': '11.0', 'Mammillary body': '18.8', 'Medium spiny neuron': '13.7', 'Mge interneuron': '6.6', 'Midbrain-derived inhibitory': '4.1', 'Miscellaneous': '22.3', 'Splatter': '5.7', 'Thalamic excitatory': '7.9', 'Upper rhombic lip': '13.2', 'Upper-layer intratelencephalic': '19.0', 'Astrocyte': '58.8', 'Bergmann glia': '2.3', 'Central nervous system macrophage': '12.1', 'Choroid plexus epithelial cell': '14.3', 'Committed oligodendrocyte precursor': '6.9', 'Ependymal cell': '102.1', 'Oligodendrocyte': '1.1', 'Oligodendrocyte precursor cell': '10.1', 'Endothelial cell': '259.2', 'Pericyte': '12.1', 'Vascular associated smooth muscle cell': '497.8', 'Fibroblast': '45.9', 'Leukocyte': '40.3', 'Basophil': '2.2', 'Eosinophil': '0.0', 'Neutrophil': '5.5', 'Classical monocyte': '137.5', 'Non-classical monocyte': '120.8', 'Intermediate monocyte': '967.9', 'T-reg': '6.1', 'GdT-cell': '0.2', 'MAIT T-cell': '3.0', 'Memory CD4 T-cell': '0.1', 'Naive CD4 T-cell': '15.9', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '20.3', 'Memory B-cell': '0.9', 'Naive B-cell': '18.5', 'Plasmacytoid DC': '11.4', 'Myeloid DC': '242.0', 'NK-cell': '6.5', 'Total PBMC': '141.2', 'Vd2 gdTCR': '3.1', 'Memory CD4 T-cell Th1\\/Th17': '13.5', 'Memory CD4 T-cell Th17': '15.4', 'Memory CD4 T-cell Th2': '20.5', 'Non-Vd2 gdTCR': '5.1', 'Memory CD4 T-cell Th1': '21.1', 'Memory CD4 T-cell TFH': '12.3', 'Terminal effector memory CD4 T-cell': '2.0', 'Central memory CD8 T-cell': '4.9', 'Effector memory CD8 T-cell': '3.9', 'Terminal effector memory CD8 T-cell': '3.5', 'Non-switched memory B-cell': '34.7', 'Plasmablast': '10.8', 'Switched memory B-cell': '24.0', 'Exhausted memory B-cell': '25.5', 'Progenitor cell': '14.7', 'Memory T-reg': '14.9', 'Naive CD4 T-cell activated': '547.8', 'Naive CD8 T-cell activated': '529.9', 'Naive T-reg': '7.4'}
2QW4, 3V3E, 3V3Q, 4JGV, 4KZI, 4KZJ, 4KZM, 4RE8, 4REE, 4REF, 4RZE, 4RZF, 4RZG, 4WHF, 4WHG, 6KZ5, 6LC1, 8WUY
{'Adipose Tissue': 379.6988264119601, 'Adrenal Gland': 208.27320542635655, 'Bladder': 181.14142857142855, 'Blood': 19.069782960172223, 'Blood Vessel': 541.9634157303371, 'Brain': 31.459206169568507, 'Breast': 228.0993246187364, 'Cervix Uteri': 143.65263157894736, 'Colon': 175.45049037227216, 'Esophagus': 147.67287543252596, 'Fallopian Tube': 598.1266666666666, 'Heart': 218.37972125435545, 'Kidney': 112.37288764044943, 'Liver': 34.39353982300885, 'Lung': 321.1919204152249, 'Muscle': 125.20646824408468, 'Nerve': 567.5872051696284, 'Ovary': 1086.1792222222225, 'Pancreas': 27.15185975609756, 'Pituitary': 456.521148409894, 'Prostate': 335.51338775510203, 'Salivary Gland': 97.48114197530865, 'Skin': 120.98553106688776, 'Small Intestine': 105.25813903743315, 'Spleen': 35.0316887966805, 'Stomach': 210.0357688022284, 'Testis': 45.84019390581718, 'Thyroid': 378.80852986217457, 'Uterus': 197.34239436619717, 'Vagina': 221.01528205128204}
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RING finger
null
null
null
VCP,AKT1,MDM2,SQSTM1, TRAF6,IKBKG
MDM2, AKT1, TRAF6, IKBKG
29
null
null
null
null
79.775479
0.523071
65.848227
0.600853
1,259
O60858
P31749
21333377
UbiNet, UbiBrowser, 31181401
TRIM13
MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '35.7', 'Basal respiratory cells': '46.2', 'Club cells': '36.4', 'Ionocytes': '45.3', 'Mucus glandular cells': '19.6', 'Serous glandular cells': '21.6', 'Gastric mucus-secreting cells': '13.6', 'Proximal enterocytes': '19.2', 'Paneth cells': '22.6', 'Distal enterocytes': '29.5', 'Intestinal goblet cells': '26.4', 'Exocrine glandular cells': '-0.691', 'Basal prostatic cells': '38.4', 'Prostatic glandular cells': '57.3', 'Breast glandular cells': '0.654', 'Breast myoepithelial cells': '0.557', 'Glandular and luminal cells': '14.3', 'Secretory cells': '25.7', 'Basal keratinocytes': '24.6', 'Suprabasal keratinocytes': '37.3', 'Basal squamous epithelial cells': '21.3', 'Squamous epithelial cells': '30.7', 'Alveolar cells type 1': '0.156', 'Alveolar cells type 2': '0.058', 'Salivary duct cells': '18.9', 'Ductal cells': '0.609', 'Hepatocytes': '0.096', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.335', 'Distal tubular cells': '12.3', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.408', 'Sertoli cells': '-0.535', 'Granulosa cells': '46.9', 'Enteroendocrine cells': '31.8', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '-0.547', 'Excitatory neurons': '29.5', 'Inhibitory neurons': '28.3', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '56.5', 'Bipolar cells': '22.0', 'Horizontal cells': '15.7', 'Astrocytes': '19.8', 'Oligodendrocyte precursor cells': '42.9', 'Oligodendrocytes': '53.5', 'Microglial cells': '34.0', 'Muller glia cells': '13.8', 'Schwann cells': '0.150', 'Spermatogonia': '-0.307', 'Spermatocytes': '0.084', 'Early spermatids': '0.882', 'Late spermatids': '0.649', 'Oocytes': '26.5', 'Cytotrophoblasts': '33.3', 'Syncytiotrophoblasts': '33.7', 'Extravillous trophoblasts': '16.6', 'Endothelial cells': '29.9', 'Lymphatic endothelial cells': '18.0', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '-0.188', 'Smooth muscle cells': '26.6', 'Adipocytes': '31.3', 'Melanocytes': '0.133', 'Fibroblasts': '24.1', 'Peritubular cells': '-0.360', 'Endometrial stromal cells': '23.3', 'Ovarian stromal cells': '27.9', 'Undifferentiated cells': '22.8', 'T-cells': '25.5', 'B-cells': '37.6', 'Plasma cells': '11.7', 'Nk-cells': '26.4', 'Granulocytes': '41.3', 'Monocytes': '32.1', 'Macrophages': '22.1', 'Hofbauer cells': '17.9', 'Kupffer cells': '16.8', 'Dendritic cells': '30.3', 'Langerhans cells': '0.265', 'Erythroid cells': '0.064', 'Adipocytes (Subcutaneous)': '-0.207', 'Adipocytes (Visceral)': '-0.380', 'Breast glandular cells (progenitors)': '0.416', 'Adipocytes (Breast)': '-0.618', 'Colon enterocytes': '0.048', 'Colon enteroendocrine cells': '0.141', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '0.151', 'Mitotic cells (Heart)': '0.485', 'Podocytes': '-0.163', 'Ascending Loop of Henle cells': '0.354', 'Intercalated cells': '-0.112', 'Cholangiocyte': '0.172', 'NK-cells (Liver)': '-0.079', 'Respiratory ciliated cells': '0.210', 'Mitotic cells (Lung)': '-0.007', 'NK-cells (Lung)': '0.157', 'B-cells (Lung)': '0.054', 'Alpha cells': '0.429', 'Beta cells': '0.264', 'Prostate glandular cells': '0.412', 'Prostate basal glandular cells': '0.532', 'Urothelial cells': '0.131', 'Keratinocyte (other)': '0.381', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.340', 'Inner root sheath cells': '-0.257', 'Outer root sheath cells': '-0.142', 'Sebaceous gland cells': '0.001', 'Eccrine sweat gland cells': '-0.215', 'Adipocytes (Skin)': '-0.313', 'Mitotic cells (Skin)': '0.144', 'Parietal cells': '-0.382', 'Chief cells': '-0.347', 'Gastric mucous cells': '-0.142', 'Gastric enteroendocrine cells': '-0.174', 'Mitotic cells (Stomach)': '0.162', 'Parafollicular cells': '-0.014', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '-0.007', 'Adrenal cortex cells': '0.320', 'Adrenal medulla cells': '0.018', 'Mitotic cells (Adrenal gland)': '0.240', 'Minor salivary glandular cells': '0.254', 'Minor salivary gland ductal cells': '0.032', 'Minor salivary gland basal cells': '0.575', 'Mitotic cells (Minor salivary gland)': '0.491', 'Adipocytes (Minor salivary gland)': '0.133', 'Somatotropes': '-0.167', 'Lactotropes': '-0.121', 'Gonadotropes': '-0.119', 'Corticotropes': '0.059', 'Thyrotropes': '0.127', 'Undifferentiated cells (Pituitary gland)': '0.293', 'Mitotic cells (Spleen)': '-0.249', 'Platelets': '-0.180', 'Erythrocytes': '-0.123', 'Hematopoietic stem cells': '-0.320', 'B-cells (Spleen)': '0.551', 'NK-cells (Spleen)': '0.395', 'Amygdala excitatory': '39.5', 'Cerebellar inhibitory': '26.5', 'Cge interneuron': '39.4', 'Deep-layer corticothalamic and 6b': '39.2', 'Deep-layer intratelencephalic': '35.2', 'Deep-layer near-projecting': '36.9', 'Eccentric medium spiny neuron': '41.9', 'Hippocampal ca1-3': '42.3', 'Hippocampal ca4': '33.9', 'Hippocampal dentate gyrus': '63.5', 'Lamp5-lhx6 and chandelier': '39.6', 'Lower rhombic lip': '51.0', 'Mammillary body': '43.9', 'Medium spiny neuron': '41.8', 'Mge interneuron': '43.1', 'Midbrain-derived inhibitory': '32.2', 'Miscellaneous': '37.1', 'Splatter': '37.5', 'Thalamic excitatory': '40.5', 'Upper rhombic lip': '76.4', 'Upper-layer intratelencephalic': '51.0', 'Astrocyte': '47.0', 'Bergmann glia': '43.8', 'Central nervous system macrophage': '120.6', 'Choroid plexus epithelial cell': '48.6', 'Committed oligodendrocyte precursor': '74.8', 'Ependymal cell': '58.9', 'Oligodendrocyte': '126.0', 'Oligodendrocyte precursor cell': '79.8', 'Endothelial cell': '95.2', 'Pericyte': '128.2', 'Vascular associated smooth muscle cell': '64.2', 'Fibroblast': '95.6', 'Leukocyte': '55.0', 'Basophil': '54.4', 'Eosinophil': '28.5', 'Neutrophil': '72.0', 'Classical monocyte': '12.3', 'Non-classical monocyte': '18.8', 'Intermediate monocyte': '37.7', 'T-reg': '46.1', 'GdT-cell': '19.0', 'MAIT T-cell': '47.1', 'Memory CD4 T-cell': '25.6', 'Naive CD4 T-cell': '25.0', 'Memory CD8 T-cell': '25.2', 'Naive CD8 T-cell': '17.0', 'Memory B-cell': '46.6', 'Naive B-cell': '39.5', 'Plasmacytoid DC': '80.5', 'Myeloid DC': '52.8', 'NK-cell': '19.2', 'Total PBMC': '44.5', 'Vd2 gdTCR': '40.7', 'Memory CD4 T-cell Th1\\/Th17': '24.1', 'Memory CD4 T-cell Th17': '25.0', 'Memory CD4 T-cell Th2': '25.5', 'Non-Vd2 gdTCR': '47.4', 'Memory CD4 T-cell Th1': '21.8', 'Memory CD4 T-cell TFH': '20.7', 'Terminal effector memory CD4 T-cell': '46.1', 'Central memory CD8 T-cell': '49.3', 'Effector memory CD8 T-cell': '51.7', 'Terminal effector memory CD8 T-cell': '51.8', 'Non-switched memory B-cell': '73.2', 'Plasmablast': '37.4', 'Switched memory B-cell': '72.4', 'Exhausted memory B-cell': '60.5', 'Progenitor cell': '65.8', 'Memory T-reg': '19.8', 'Naive CD4 T-cell activated': '16.7', 'Naive CD8 T-cell activated': '12.1', 'Naive T-reg': '22.9'}
null
{'Adipose Tissue': 9.431014950166112, 'Adrenal Gland': 7.125096899224807, 'Bladder': 10.608285714285714, 'Blood': 4.998763509149623, 'Blood Vessel': 11.487531086142322, 'Brain': 6.6067780847842545, 'Breast': 10.684084967320262, 'Cervix Uteri': 12.674736842105265, 'Colon': 10.200605905006418, 'Esophagus': 13.939683737024222, 'Fallopian Tube': 13.330666666666666, 'Heart': 3.9377188153310105, 'Kidney': 6.1288426966292135, 'Liver': 3.348150442477876, 'Lung': 14.11987197231834, 'Muscle': 6.039047322540473, 'Nerve': 13.861156704361877, 'Ovary': 12.146372222222224, 'Pancreas': 3.732479573170732, 'Pituitary': 10.571583038869257, 'Prostate': 14.106820408163264, 'Salivary Gland': 10.103123456790122, 'Skin': 14.289758430071862, 'Small Intestine': 11.249764705882354, 'Spleen': 12.711033195020748, 'Stomach': 7.44783008356546, 'Testis': 37.17598337950139, 'Thyroid': 13.078012251148545, 'Uterus': 13.399830985915491, 'Vagina': 13.23275}
AKT1
MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
Homo sapiens
Cytoplasm, Nucleus, Cell membrane, Mitochondrion intermembrane space
Low tissue specificity
{'Ciliated cells': '23.3', 'Basal respiratory cells': '17.3', 'Club cells': '35.1', 'Ionocytes': '28.0', 'Mucus glandular cells': '31.2', 'Serous glandular cells': '31.2', 'Gastric mucus-secreting cells': '24.8', 'Proximal enterocytes': '20.9', 'Paneth cells': '20.6', 'Distal enterocytes': '33.7', 'Intestinal goblet cells': '40.0', 'Exocrine glandular cells': '-0.639', 'Basal prostatic cells': '25.2', 'Prostatic glandular cells': '37.3', 'Breast glandular cells': '0.275', 'Breast myoepithelial cells': '0.049', 'Glandular and luminal cells': '23.8', 'Secretory cells': '30.0', 'Basal keratinocytes': '22.2', 'Suprabasal keratinocytes': '19.3', 'Basal squamous epithelial cells': '10.9', 'Squamous epithelial cells': '16.2', 'Alveolar cells type 1': '0.158', 'Alveolar cells type 2': '0.065', 'Salivary duct cells': '26.5', 'Ductal cells': '0.616', 'Hepatocytes': '0.362', 'Cholangiocytes': '30.5', 'Proximal tubular cells': '0.176', 'Distal tubular cells': '9.2', 'Collecting duct cells': '17.5', 'Mesothelial cells': '-0.073', 'Sertoli cells': '0.683', 'Granulosa cells': '19.5', 'Enteroendocrine cells': '24.0', 'Pancreatic endocrine cells': '22.1', 'Leydig cells': '0.645', 'Excitatory neurons': '7.9', 'Inhibitory neurons': '12.5', 'Cone photoreceptor cells': '32.3', 'Rod photoreceptor cells': '24.9', 'Bipolar cells': '23.3', 'Horizontal cells': '38.4', 'Astrocytes': '15.8', 'Oligodendrocyte precursor cells': '7.5', 'Oligodendrocytes': '8.9', 'Microglial cells': '6.3', 'Muller glia cells': '52.3', 'Schwann cells': '0.020', 'Spermatogonia': '0.440', 'Spermatocytes': '0.005', 'Early spermatids': '-0.663', 'Late spermatids': '-0.674', 'Oocytes': '3.7', 'Cytotrophoblasts': '20.0', 'Syncytiotrophoblasts': '21.7', 'Extravillous trophoblasts': '34.8', 'Endothelial cells': '31.6', 'Lymphatic endothelial cells': '31.3', 'Cardiomyocytes': '0.657', 'Skeletal myocytes': '-0.233', 'Smooth muscle cells': '35.3', 'Adipocytes': '41.8', 'Melanocytes': '-0.022', 'Fibroblasts': '27.4', 'Peritubular cells': '0.471', 'Endometrial stromal cells': '27.5', 'Ovarian stromal cells': '14.6', 'Undifferentiated cells': '29.4', 'T-cells': '25.4', 'B-cells': '15.6', 'Plasma cells': '16.7', 'Nk-cells': '38.9', 'Granulocytes': '30.8', 'Monocytes': '42.1', 'Macrophages': '33.8', 'Hofbauer cells': '24.9', 'Kupffer cells': '44.1', 'Dendritic cells': '27.7', 'Langerhans cells': '0.069', 'Erythroid cells': '-0.038', 'Adipocytes (Subcutaneous)': '0.342', 'Adipocytes (Visceral)': '0.375', 'Breast glandular cells (progenitors)': '0.097', 'Adipocytes (Breast)': '0.046', 'Colon enterocytes': '-0.143', 'Colon enteroendocrine cells': '0.152', 'Enteric glia cells': '-0.214', 'Mitotic cells (Colon)': '-0.123', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.119', 'Ascending Loop of Henle cells': '0.370', 'Intercalated cells': '-0.105', 'Cholangiocyte': '0.285', 'NK-cells (Liver)': '-0.340', 'Respiratory ciliated cells': '-0.057', 'Mitotic cells (Lung)': '-0.018', 'NK-cells (Lung)': '0.036', 'B-cells (Lung)': '-0.149', 'Alpha cells': '0.385', 'Beta cells': '0.250', 'Prostate glandular cells': '0.062', 'Prostate basal glandular cells': '0.190', 'Urothelial cells': '0.144', 'Keratinocyte (other)': '-0.231', 'Keratinocyte (granular)': '-0.292', 'Hair cortex cells': '0.268', 'Inner root sheath cells': '0.326', 'Outer root sheath cells': '0.443', 'Sebaceous gland cells': '0.106', 'Eccrine sweat gland cells': '0.274', 'Adipocytes (Skin)': '0.170', 'Mitotic cells (Skin)': '0.122', 'Parietal cells': '-0.503', 'Chief cells': '-0.372', 'Gastric mucous cells': '-0.294', 'Gastric enteroendocrine cells': '-0.305', 'Mitotic cells (Stomach)': '0.097', 'Parafollicular cells': '0.082', 'Thyroid glandular cells': '0.219', 'Mitotic cells (Thyroid)': '-0.047', 'Adrenal cortex cells': '0.414', 'Adrenal medulla cells': '0.016', 'Mitotic cells (Adrenal gland)': '0.220', 'Minor salivary glandular cells': '0.377', 'Minor salivary gland ductal cells': '0.277', 'Minor salivary gland basal cells': '0.048', 'Mitotic cells (Minor salivary gland)': '-0.091', 'Adipocytes (Minor salivary gland)': '0.036', 'Somatotropes': '-0.187', 'Lactotropes': '-0.301', 'Gonadotropes': '-0.099', 'Corticotropes': '-0.241', 'Thyrotropes': '-0.044', 'Undifferentiated cells (Pituitary gland)': '0.430', 'Mitotic cells (Spleen)': '-0.381', 'Platelets': '-0.218', 'Erythrocytes': '-0.159', 'Hematopoietic stem cells': '-0.342', 'B-cells (Spleen)': '0.225', 'NK-cells (Spleen)': '0.295', 'Amygdala excitatory': '12.4', 'Cerebellar inhibitory': '11.8', 'Cge interneuron': '19.2', 'Deep-layer corticothalamic and 6b': '12.2', 'Deep-layer intratelencephalic': '12.2', 'Deep-layer near-projecting': '17.5', 'Eccentric medium spiny neuron': '16.0', 'Hippocampal ca1-3': '15.5', 'Hippocampal ca4': '10.3', 'Hippocampal dentate gyrus': '8.7', 'Lamp5-lhx6 and chandelier': '20.3', 'Lower rhombic lip': '12.2', 'Mammillary body': '16.6', 'Medium spiny neuron': '12.6', 'Mge interneuron': '20.7', 'Midbrain-derived inhibitory': '16.7', 'Miscellaneous': '17.5', 'Splatter': '15.6', 'Thalamic excitatory': '14.8', 'Upper rhombic lip': '15.0', 'Upper-layer intratelencephalic': '12.4', 'Astrocyte': '21.6', 'Bergmann glia': '26.9', 'Central nervous system macrophage': '23.2', 'Choroid plexus epithelial cell': '20.9', 'Committed oligodendrocyte precursor': '18.9', 'Ependymal cell': '28.4', 'Oligodendrocyte': '15.2', 'Oligodendrocyte precursor cell': '20.2', 'Endothelial cell': '29.9', 'Pericyte': '33.7', 'Vascular associated smooth muscle cell': '24.7', 'Fibroblast': '21.2', 'Leukocyte': '33.7', 'Basophil': '7.6', 'Eosinophil': '24.3', 'Neutrophil': '16.1', 'Classical monocyte': '32.1', 'Non-classical monocyte': '29.1', 'Intermediate monocyte': '9.7', 'T-reg': '3.6', 'GdT-cell': '2.5', 'MAIT T-cell': '7.7', 'Memory CD4 T-cell': '3.3', 'Naive CD4 T-cell': '18.2', 'Memory CD8 T-cell': '3.8', 'Naive CD8 T-cell': '25.2', 'Memory B-cell': '1.6', 'Naive B-cell': '14.9', 'Plasmacytoid DC': '4.2', 'Myeloid DC': '9.3', 'NK-cell': '52.2', 'Total PBMC': '5.3', 'Vd2 gdTCR': '9.3', 'Memory CD4 T-cell TFH': '43.7', 'Memory CD4 T-cell Th2': '31.1', 'Memory CD4 T-cell Th17': '30.8', 'Memory CD4 T-cell Th1\\/Th17': '23.3', 'Non-Vd2 gdTCR': '11.1', 'Memory CD4 T-cell Th1': '36.6', 'Terminal effector memory CD4 T-cell': '3.0', 'Central memory CD8 T-cell': '3.4', 'Effector memory CD8 T-cell': '6.2', 'Terminal effector memory CD8 T-cell': '5.3', 'Switched memory B-cell': '3.3', 'Plasmablast': '5.8', 'Non-switched memory B-cell': '3.0', 'Exhausted memory B-cell': '4.5', 'Progenitor cell': '1.3', 'Naive CD4 T-cell activated': '11.7', 'Naive CD8 T-cell activated': '15.6', 'Memory T-reg': '46.8', 'Naive T-reg': '28.8'}
1H10, 1UNP, 1UNQ, 1UNR, 2UVM, 2UZR, 2UZS, 3CQU, 3CQW, 3MV5, 3MVH, 3O96, 3OCB, 3OW4, 3QKK, 3QKL, 3QKM, 4EJN, 4EKK, 4EKL, 4GV1, 5KCV, 6BUU, 6CCY, 6HHF, 6HHG, 6HHH, 6HHI, 6HHJ, 6NPZ, 6S9W, 6S9X, 7APJ, 7MYX, 7NH4, 7NH5
{'Adipose Tissue': 60.44132890365449, 'Adrenal Gland': 75.2067441860465, 'Bladder': 71.63095238095238, 'Blood': 34.672583423035526, 'Blood Vessel': 83.6603520599251, 'Brain': 28.339509841029525, 'Breast': 60.844618736383445, 'Cervix Uteri': 67.21842105263158, 'Colon': 64.59388960205392, 'Esophagus': 64.20851833910034, 'Fallopian Tube': 65.78888888888889, 'Heart': 30.7124262485482, 'Kidney': 31.1176404494382, 'Liver': 34.80755309734513, 'Lung': 81.07410034602077, 'Muscle': 23.696343711083436, 'Nerve': 66.50266558966075, 'Ovary': 55.0055, 'Pancreas': 28.278545731707315, 'Pituitary': 39.506254416961134, 'Prostate': 71.23767346938776, 'Salivary Gland': 52.016728395061726, 'Skin': 52.04238253178551, 'Small Intestine': 50.156898395721925, 'Spleen': 64.10705394190872, 'Stomach': 55.306072423398334, 'Testis': 34.37623268698061, 'Thyroid': 69.0986830015314, 'Uterus': 69.966338028169, 'Vagina': 55.19378205128205}
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RING finger
null
null
null
VCP,AKT1,MDM2,SQSTM1, TRAF6,IKBKG
MDM2, AKT1, TRAF6, IKBKG
29
null
null
null
null
79.775479
0.523071
82.342938
0.363125
1,650
O60858
P31751
21333377
UbiNet, UbiBrowser
TRIM13
MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '35.7', 'Basal respiratory cells': '46.2', 'Club cells': '36.4', 'Ionocytes': '45.3', 'Mucus glandular cells': '19.6', 'Serous glandular cells': '21.6', 'Gastric mucus-secreting cells': '13.6', 'Proximal enterocytes': '19.2', 'Paneth cells': '22.6', 'Distal enterocytes': '29.5', 'Intestinal goblet cells': '26.4', 'Exocrine glandular cells': '-0.691', 'Basal prostatic cells': '38.4', 'Prostatic glandular cells': '57.3', 'Breast glandular cells': '0.654', 'Breast myoepithelial cells': '0.557', 'Glandular and luminal cells': '14.3', 'Secretory cells': '25.7', 'Basal keratinocytes': '24.6', 'Suprabasal keratinocytes': '37.3', 'Basal squamous epithelial cells': '21.3', 'Squamous epithelial cells': '30.7', 'Alveolar cells type 1': '0.156', 'Alveolar cells type 2': '0.058', 'Salivary duct cells': '18.9', 'Ductal cells': '0.609', 'Hepatocytes': '0.096', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.335', 'Distal tubular cells': '12.3', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.408', 'Sertoli cells': '-0.535', 'Granulosa cells': '46.9', 'Enteroendocrine cells': '31.8', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '-0.547', 'Excitatory neurons': '29.5', 'Inhibitory neurons': '28.3', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '56.5', 'Bipolar cells': '22.0', 'Horizontal cells': '15.7', 'Astrocytes': '19.8', 'Oligodendrocyte precursor cells': '42.9', 'Oligodendrocytes': '53.5', 'Microglial cells': '34.0', 'Muller glia cells': '13.8', 'Schwann cells': '0.150', 'Spermatogonia': '-0.307', 'Spermatocytes': '0.084', 'Early spermatids': '0.882', 'Late spermatids': '0.649', 'Oocytes': '26.5', 'Cytotrophoblasts': '33.3', 'Syncytiotrophoblasts': '33.7', 'Extravillous trophoblasts': '16.6', 'Endothelial cells': '29.9', 'Lymphatic endothelial cells': '18.0', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '-0.188', 'Smooth muscle cells': '26.6', 'Adipocytes': '31.3', 'Melanocytes': '0.133', 'Fibroblasts': '24.1', 'Peritubular cells': '-0.360', 'Endometrial stromal cells': '23.3', 'Ovarian stromal cells': '27.9', 'Undifferentiated cells': '22.8', 'T-cells': '25.5', 'B-cells': '37.6', 'Plasma cells': '11.7', 'Nk-cells': '26.4', 'Granulocytes': '41.3', 'Monocytes': '32.1', 'Macrophages': '22.1', 'Hofbauer cells': '17.9', 'Kupffer cells': '16.8', 'Dendritic cells': '30.3', 'Langerhans cells': '0.265', 'Erythroid cells': '0.064', 'Adipocytes (Subcutaneous)': '-0.207', 'Adipocytes (Visceral)': '-0.380', 'Breast glandular cells (progenitors)': '0.416', 'Adipocytes (Breast)': '-0.618', 'Colon enterocytes': '0.048', 'Colon enteroendocrine cells': '0.141', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '0.151', 'Mitotic cells (Heart)': '0.485', 'Podocytes': '-0.163', 'Ascending Loop of Henle cells': '0.354', 'Intercalated cells': '-0.112', 'Cholangiocyte': '0.172', 'NK-cells (Liver)': '-0.079', 'Respiratory ciliated cells': '0.210', 'Mitotic cells (Lung)': '-0.007', 'NK-cells (Lung)': '0.157', 'B-cells (Lung)': '0.054', 'Alpha cells': '0.429', 'Beta cells': '0.264', 'Prostate glandular cells': '0.412', 'Prostate basal glandular cells': '0.532', 'Urothelial cells': '0.131', 'Keratinocyte (other)': '0.381', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.340', 'Inner root sheath cells': '-0.257', 'Outer root sheath cells': '-0.142', 'Sebaceous gland cells': '0.001', 'Eccrine sweat gland cells': '-0.215', 'Adipocytes (Skin)': '-0.313', 'Mitotic cells (Skin)': '0.144', 'Parietal cells': '-0.382', 'Chief cells': '-0.347', 'Gastric mucous cells': '-0.142', 'Gastric enteroendocrine cells': '-0.174', 'Mitotic cells (Stomach)': '0.162', 'Parafollicular cells': '-0.014', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '-0.007', 'Adrenal cortex cells': '0.320', 'Adrenal medulla cells': '0.018', 'Mitotic cells (Adrenal gland)': '0.240', 'Minor salivary glandular cells': '0.254', 'Minor salivary gland ductal cells': '0.032', 'Minor salivary gland basal cells': '0.575', 'Mitotic cells (Minor salivary gland)': '0.491', 'Adipocytes (Minor salivary gland)': '0.133', 'Somatotropes': '-0.167', 'Lactotropes': '-0.121', 'Gonadotropes': '-0.119', 'Corticotropes': '0.059', 'Thyrotropes': '0.127', 'Undifferentiated cells (Pituitary gland)': '0.293', 'Mitotic cells (Spleen)': '-0.249', 'Platelets': '-0.180', 'Erythrocytes': '-0.123', 'Hematopoietic stem cells': '-0.320', 'B-cells (Spleen)': '0.551', 'NK-cells (Spleen)': '0.395', 'Amygdala excitatory': '39.5', 'Cerebellar inhibitory': '26.5', 'Cge interneuron': '39.4', 'Deep-layer corticothalamic and 6b': '39.2', 'Deep-layer intratelencephalic': '35.2', 'Deep-layer near-projecting': '36.9', 'Eccentric medium spiny neuron': '41.9', 'Hippocampal ca1-3': '42.3', 'Hippocampal ca4': '33.9', 'Hippocampal dentate gyrus': '63.5', 'Lamp5-lhx6 and chandelier': '39.6', 'Lower rhombic lip': '51.0', 'Mammillary body': '43.9', 'Medium spiny neuron': '41.8', 'Mge interneuron': '43.1', 'Midbrain-derived inhibitory': '32.2', 'Miscellaneous': '37.1', 'Splatter': '37.5', 'Thalamic excitatory': '40.5', 'Upper rhombic lip': '76.4', 'Upper-layer intratelencephalic': '51.0', 'Astrocyte': '47.0', 'Bergmann glia': '43.8', 'Central nervous system macrophage': '120.6', 'Choroid plexus epithelial cell': '48.6', 'Committed oligodendrocyte precursor': '74.8', 'Ependymal cell': '58.9', 'Oligodendrocyte': '126.0', 'Oligodendrocyte precursor cell': '79.8', 'Endothelial cell': '95.2', 'Pericyte': '128.2', 'Vascular associated smooth muscle cell': '64.2', 'Fibroblast': '95.6', 'Leukocyte': '55.0', 'Basophil': '54.4', 'Eosinophil': '28.5', 'Neutrophil': '72.0', 'Classical monocyte': '12.3', 'Non-classical monocyte': '18.8', 'Intermediate monocyte': '37.7', 'T-reg': '46.1', 'GdT-cell': '19.0', 'MAIT T-cell': '47.1', 'Memory CD4 T-cell': '25.6', 'Naive CD4 T-cell': '25.0', 'Memory CD8 T-cell': '25.2', 'Naive CD8 T-cell': '17.0', 'Memory B-cell': '46.6', 'Naive B-cell': '39.5', 'Plasmacytoid DC': '80.5', 'Myeloid DC': '52.8', 'NK-cell': '19.2', 'Total PBMC': '44.5', 'Vd2 gdTCR': '40.7', 'Memory CD4 T-cell Th1\\/Th17': '24.1', 'Memory CD4 T-cell Th17': '25.0', 'Memory CD4 T-cell Th2': '25.5', 'Non-Vd2 gdTCR': '47.4', 'Memory CD4 T-cell Th1': '21.8', 'Memory CD4 T-cell TFH': '20.7', 'Terminal effector memory CD4 T-cell': '46.1', 'Central memory CD8 T-cell': '49.3', 'Effector memory CD8 T-cell': '51.7', 'Terminal effector memory CD8 T-cell': '51.8', 'Non-switched memory B-cell': '73.2', 'Plasmablast': '37.4', 'Switched memory B-cell': '72.4', 'Exhausted memory B-cell': '60.5', 'Progenitor cell': '65.8', 'Memory T-reg': '19.8', 'Naive CD4 T-cell activated': '16.7', 'Naive CD8 T-cell activated': '12.1', 'Naive T-reg': '22.9'}
null
{'Adipose Tissue': 9.431014950166112, 'Adrenal Gland': 7.125096899224807, 'Bladder': 10.608285714285714, 'Blood': 4.998763509149623, 'Blood Vessel': 11.487531086142322, 'Brain': 6.6067780847842545, 'Breast': 10.684084967320262, 'Cervix Uteri': 12.674736842105265, 'Colon': 10.200605905006418, 'Esophagus': 13.939683737024222, 'Fallopian Tube': 13.330666666666666, 'Heart': 3.9377188153310105, 'Kidney': 6.1288426966292135, 'Liver': 3.348150442477876, 'Lung': 14.11987197231834, 'Muscle': 6.039047322540473, 'Nerve': 13.861156704361877, 'Ovary': 12.146372222222224, 'Pancreas': 3.732479573170732, 'Pituitary': 10.571583038869257, 'Prostate': 14.106820408163264, 'Salivary Gland': 10.103123456790122, 'Skin': 14.289758430071862, 'Small Intestine': 11.249764705882354, 'Spleen': 12.711033195020748, 'Stomach': 7.44783008356546, 'Testis': 37.17598337950139, 'Thyroid': 13.078012251148545, 'Uterus': 13.399830985915491, 'Vagina': 13.23275}
AKT2
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIRE
Homo sapiens
Cytoplasm, Nucleus, Cell membrane, Early endosome
Low tissue specificity
{'Ciliated cells': '32.9', 'Basal respiratory cells': '20.2', 'Club cells': '25.9', 'Ionocytes': '24.3', 'Mucus glandular cells': '21.7', 'Serous glandular cells': '16.0', 'Gastric mucus-secreting cells': '18.9', 'Proximal enterocytes': '18.5', 'Paneth cells': '15.8', 'Distal enterocytes': '18.5', 'Intestinal goblet cells': '17.3', 'Exocrine glandular cells': '-0.673', 'Basal prostatic cells': '32.0', 'Prostatic glandular cells': '27.1', 'Breast glandular cells': '0.242', 'Breast myoepithelial cells': '0.039', 'Glandular and luminal cells': '23.4', 'Secretory cells': '23.6', 'Basal keratinocytes': '28.6', 'Suprabasal keratinocytes': '34.9', 'Basal squamous epithelial cells': '26.4', 'Squamous epithelial cells': '30.6', 'Alveolar cells type 1': '0.094', 'Alveolar cells type 2': '-0.400', 'Salivary duct cells': '19.3', 'Ductal cells': '0.540', 'Hepatocytes': '0.389', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.184', 'Distal tubular cells': '9.2', 'Collecting duct cells': '70.0', 'Mesothelial cells': '0.227', 'Sertoli cells': '0.681', 'Granulosa cells': '26.8', 'Enteroendocrine cells': '18.1', 'Pancreatic endocrine cells': '13.6', 'Leydig cells': '0.472', 'Excitatory neurons': '29.3', 'Inhibitory neurons': '24.2', 'Cone photoreceptor cells': '20.4', 'Rod photoreceptor cells': '102.9', 'Bipolar cells': '59.3', 'Horizontal cells': '61.7', 'Astrocytes': '48.6', 'Oligodendrocyte precursor cells': '39.1', 'Oligodendrocytes': '37.8', 'Microglial cells': '22.4', 'Muller glia cells': '44.0', 'Schwann cells': '0.018', 'Spermatogonia': '0.390', 'Spermatocytes': '0.084', 'Early spermatids': '-0.463', 'Late spermatids': '-0.597', 'Oocytes': '5.9', 'Cytotrophoblasts': '31.6', 'Syncytiotrophoblasts': '40.0', 'Extravillous trophoblasts': '24.4', 'Endothelial cells': '17.2', 'Lymphatic endothelial cells': '20.6', 'Cardiomyocytes': '0.684', 'Skeletal myocytes': '-0.011', 'Smooth muscle cells': '24.4', 'Adipocytes': '16.9', 'Melanocytes': '0.085', 'Fibroblasts': '26.5', 'Peritubular cells': '0.488', 'Endometrial stromal cells': '24.4', 'Ovarian stromal cells': '35.2', 'Undifferentiated cells': '19.4', 'T-cells': '25.7', 'B-cells': '31.6', 'Plasma cells': '27.8', 'Nk-cells': '44.6', 'Granulocytes': '18.7', 'Monocytes': '34.0', 'Macrophages': '20.1', 'Hofbauer cells': '21.9', 'Kupffer cells': '27.8', 'Dendritic cells': '25.4', 'Langerhans cells': '0.179', 'Erythroid cells': '-0.063', 'Adipocytes (Subcutaneous)': '0.559', 'Adipocytes (Visceral)': '0.477', 'Breast glandular cells (progenitors)': '0.067', 'Adipocytes (Breast)': '0.250', 'Colon enterocytes': '-0.269', 'Colon enteroendocrine cells': '0.216', 'Enteric glia cells': '0.471', 'Mitotic cells (Colon)': '-0.273', 'Mitotic cells (Heart)': '0.469', 'Podocytes': '-0.129', 'Ascending Loop of Henle cells': '0.512', 'Intercalated cells': '-0.055', 'Cholangiocyte': '0.117', 'NK-cells (Liver)': '-0.172', 'Respiratory ciliated cells': '0.246', 'Mitotic cells (Lung)': '-0.149', 'NK-cells (Lung)': '0.365', 'B-cells (Lung)': '0.235', 'Alpha cells': '0.404', 'Beta cells': '0.271', 'Prostate glandular cells': '-0.092', 'Prostate basal glandular cells': '0.207', 'Urothelial cells': '0.339', 'Keratinocyte (other)': '0.102', 'Keratinocyte (granular)': '0.043', 'Hair cortex cells': '-0.086', 'Inner root sheath cells': '-0.054', 'Outer root sheath cells': '0.109', 'Sebaceous gland cells': '-0.014', 'Eccrine sweat gland cells': '-0.180', 'Adipocytes (Skin)': '-0.043', 'Mitotic cells (Skin)': '0.137', 'Parietal cells': '-0.723', 'Chief cells': '-0.595', 'Gastric mucous cells': '-0.435', 'Gastric enteroendocrine cells': '-0.415', 'Mitotic cells (Stomach)': '-0.019', 'Parafollicular cells': '0.139', 'Thyroid glandular cells': '0.352', 'Mitotic cells (Thyroid)': '-0.045', 'Adrenal cortex cells': '0.325', 'Adrenal medulla cells': '-0.103', 'Mitotic cells (Adrenal gland)': '0.008', 'Minor salivary glandular cells': '0.279', 'Minor salivary gland ductal cells': '-0.019', 'Minor salivary gland basal cells': '0.296', 'Mitotic cells (Minor salivary gland)': '0.376', 'Adipocytes (Minor salivary gland)': '0.236', 'Somatotropes': '0.179', 'Lactotropes': '0.166', 'Gonadotropes': '0.200', 'Corticotropes': '0.030', 'Thyrotropes': '0.181', 'Undifferentiated cells (Pituitary gland)': '0.063', 'Mitotic cells (Spleen)': '-0.313', 'Platelets': '-0.266', 'Erythrocytes': '-0.150', 'Hematopoietic stem cells': '-0.391', 'B-cells (Spleen)': '0.510', 'NK-cells (Spleen)': '0.327', 'Amygdala excitatory': '54.0', 'Cerebellar inhibitory': '47.2', 'Cge interneuron': '38.9', 'Deep-layer corticothalamic and 6b': '61.9', 'Deep-layer intratelencephalic': '61.4', 'Deep-layer near-projecting': '58.6', 'Eccentric medium spiny neuron': '41.9', 'Hippocampal ca1-3': '41.2', 'Hippocampal ca4': '31.8', 'Hippocampal dentate gyrus': '41.9', 'Lamp5-lhx6 and chandelier': '41.5', 'Lower rhombic lip': '32.3', 'Mammillary body': '39.0', 'Medium spiny neuron': '53.3', 'Mge interneuron': '40.8', 'Midbrain-derived inhibitory': '30.3', 'Miscellaneous': '50.0', 'Splatter': '34.4', 'Thalamic excitatory': '28.0', 'Upper rhombic lip': '62.3', 'Upper-layer intratelencephalic': '61.7', 'Astrocyte': '86.6', 'Bergmann glia': '111.0', 'Central nervous system macrophage': '33.3', 'Choroid plexus epithelial cell': '121.0', 'Committed oligodendrocyte precursor': '51.4', 'Ependymal cell': '60.3', 'Oligodendrocyte': '64.5', 'Oligodendrocyte precursor cell': '77.9', 'Endothelial cell': '38.8', 'Pericyte': '41.0', 'Vascular associated smooth muscle cell': '47.8', 'Fibroblast': '61.9', 'Leukocyte': '49.7', 'Basophil': '36.2', 'Eosinophil': '2.1', 'Neutrophil': '34.9', 'Classical monocyte': '20.5', 'Non-classical monocyte': '23.4', 'Intermediate monocyte': '16.2', 'T-reg': '35.9', 'GdT-cell': '2.2', 'MAIT T-cell': '42.5', 'Memory CD4 T-cell': '1.8', 'Naive CD4 T-cell': '36.0', 'Memory CD8 T-cell': '1.5', 'Naive CD8 T-cell': '49.6', 'Memory B-cell': '2.0', 'Naive B-cell': '40.8', 'Plasmacytoid DC': '39.1', 'Myeloid DC': '25.5', 'NK-cell': '49.8', 'Total PBMC': '23.7', 'Vd2 gdTCR': '41.5', 'Memory CD4 T-cell TFH': '54.7', 'Memory CD4 T-cell Th2': '40.4', 'Memory CD4 T-cell Th17': '36.5', 'Memory CD4 T-cell Th1\\/Th17': '28.2', 'Non-Vd2 gdTCR': '38.5', 'Memory CD4 T-cell Th1': '41.4', 'Terminal effector memory CD4 T-cell': '33.5', 'Central memory CD8 T-cell': '46.8', 'Effector memory CD8 T-cell': '33.1', 'Terminal effector memory CD8 T-cell': '33.7', 'Switched memory B-cell': '46.3', 'Plasmablast': '17.8', 'Non-switched memory B-cell': '46.0', 'Exhausted memory B-cell': '41.7', 'Progenitor cell': '48.1', 'Naive CD4 T-cell activated': '38.6', 'Naive CD8 T-cell activated': '42.2', 'Memory T-reg': '52.0', 'Naive T-reg': '44.6'}
1GZK, 1GZN, 1GZO, 1MRV, 1MRY, 1O6K, 1O6L, 1P6S, 2JDO, 2JDR, 2UW9, 2X39, 2XH5, 3D0E, 3E87, 3E88, 3E8D, 8Q61
{'Adipose Tissue': 40.5477657807309, 'Adrenal Gland': 33.32282945736434, 'Bladder': 43.38142857142857, 'Blood': 26.010570505920345, 'Blood Vessel': 36.9101722846442, 'Brain': 26.680366010598032, 'Breast': 39.991503267973854, 'Cervix Uteri': 67.31736842105263, 'Colon': 36.115173299101414, 'Esophagus': 36.27926782006921, 'Fallopian Tube': 59.056666666666665, 'Heart': 17.579832752613243, 'Kidney': 29.867078651685393, 'Liver': 28.277141592920355, 'Lung': 35.714411764705886, 'Muscle': 40.88518057285181, 'Nerve': 47.66841680129241, 'Ovary': 70.14005555555555, 'Pancreas': 16.184576219512195, 'Pituitary': 53.99388692579505, 'Prostate': 50.15877551020408, 'Salivary Gland': 27.001419753086417, 'Skin': 37.23545052515201, 'Small Intestine': 32.79978609625669, 'Spleen': 39.10800829875519, 'Stomach': 24.583922005571033, 'Testis': 43.90653739612189, 'Thyroid': 100.19290964777947, 'Uterus': 64.25964788732395, 'Vagina': 49.637307692307694}
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RING finger
null
null
null
VCP,AKT1,MDM2,SQSTM1, TRAF6,IKBKG
MDM2, AKT1, TRAF6, IKBKG
29
null
null
null
null
79.775479
0.523071
82.061414
0.355842
1,650
O60858
P55072
22199232, hUbiquitome
UbiNet, UbiBrowser, 31181401
TRIM13
MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '35.7', 'Basal respiratory cells': '46.2', 'Club cells': '36.4', 'Ionocytes': '45.3', 'Mucus glandular cells': '19.6', 'Serous glandular cells': '21.6', 'Gastric mucus-secreting cells': '13.6', 'Proximal enterocytes': '19.2', 'Paneth cells': '22.6', 'Distal enterocytes': '29.5', 'Intestinal goblet cells': '26.4', 'Exocrine glandular cells': '-0.691', 'Basal prostatic cells': '38.4', 'Prostatic glandular cells': '57.3', 'Breast glandular cells': '0.654', 'Breast myoepithelial cells': '0.557', 'Glandular and luminal cells': '14.3', 'Secretory cells': '25.7', 'Basal keratinocytes': '24.6', 'Suprabasal keratinocytes': '37.3', 'Basal squamous epithelial cells': '21.3', 'Squamous epithelial cells': '30.7', 'Alveolar cells type 1': '0.156', 'Alveolar cells type 2': '0.058', 'Salivary duct cells': '18.9', 'Ductal cells': '0.609', 'Hepatocytes': '0.096', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.335', 'Distal tubular cells': '12.3', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.408', 'Sertoli cells': '-0.535', 'Granulosa cells': '46.9', 'Enteroendocrine cells': '31.8', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '-0.547', 'Excitatory neurons': '29.5', 'Inhibitory neurons': '28.3', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '56.5', 'Bipolar cells': '22.0', 'Horizontal cells': '15.7', 'Astrocytes': '19.8', 'Oligodendrocyte precursor cells': '42.9', 'Oligodendrocytes': '53.5', 'Microglial cells': '34.0', 'Muller glia cells': '13.8', 'Schwann cells': '0.150', 'Spermatogonia': '-0.307', 'Spermatocytes': '0.084', 'Early spermatids': '0.882', 'Late spermatids': '0.649', 'Oocytes': '26.5', 'Cytotrophoblasts': '33.3', 'Syncytiotrophoblasts': '33.7', 'Extravillous trophoblasts': '16.6', 'Endothelial cells': '29.9', 'Lymphatic endothelial cells': '18.0', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '-0.188', 'Smooth muscle cells': '26.6', 'Adipocytes': '31.3', 'Melanocytes': '0.133', 'Fibroblasts': '24.1', 'Peritubular cells': '-0.360', 'Endometrial stromal cells': '23.3', 'Ovarian stromal cells': '27.9', 'Undifferentiated cells': '22.8', 'T-cells': '25.5', 'B-cells': '37.6', 'Plasma cells': '11.7', 'Nk-cells': '26.4', 'Granulocytes': '41.3', 'Monocytes': '32.1', 'Macrophages': '22.1', 'Hofbauer cells': '17.9', 'Kupffer cells': '16.8', 'Dendritic cells': '30.3', 'Langerhans cells': '0.265', 'Erythroid cells': '0.064', 'Adipocytes (Subcutaneous)': '-0.207', 'Adipocytes (Visceral)': '-0.380', 'Breast glandular cells (progenitors)': '0.416', 'Adipocytes (Breast)': '-0.618', 'Colon enterocytes': '0.048', 'Colon enteroendocrine cells': '0.141', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '0.151', 'Mitotic cells (Heart)': '0.485', 'Podocytes': '-0.163', 'Ascending Loop of Henle cells': '0.354', 'Intercalated cells': '-0.112', 'Cholangiocyte': '0.172', 'NK-cells (Liver)': '-0.079', 'Respiratory ciliated cells': '0.210', 'Mitotic cells (Lung)': '-0.007', 'NK-cells (Lung)': '0.157', 'B-cells (Lung)': '0.054', 'Alpha cells': '0.429', 'Beta cells': '0.264', 'Prostate glandular cells': '0.412', 'Prostate basal glandular cells': '0.532', 'Urothelial cells': '0.131', 'Keratinocyte (other)': '0.381', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.340', 'Inner root sheath cells': '-0.257', 'Outer root sheath cells': '-0.142', 'Sebaceous gland cells': '0.001', 'Eccrine sweat gland cells': '-0.215', 'Adipocytes (Skin)': '-0.313', 'Mitotic cells (Skin)': '0.144', 'Parietal cells': '-0.382', 'Chief cells': '-0.347', 'Gastric mucous cells': '-0.142', 'Gastric enteroendocrine cells': '-0.174', 'Mitotic cells (Stomach)': '0.162', 'Parafollicular cells': '-0.014', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '-0.007', 'Adrenal cortex cells': '0.320', 'Adrenal medulla cells': '0.018', 'Mitotic cells (Adrenal gland)': '0.240', 'Minor salivary glandular cells': '0.254', 'Minor salivary gland ductal cells': '0.032', 'Minor salivary gland basal cells': '0.575', 'Mitotic cells (Minor salivary gland)': '0.491', 'Adipocytes (Minor salivary gland)': '0.133', 'Somatotropes': '-0.167', 'Lactotropes': '-0.121', 'Gonadotropes': '-0.119', 'Corticotropes': '0.059', 'Thyrotropes': '0.127', 'Undifferentiated cells (Pituitary gland)': '0.293', 'Mitotic cells (Spleen)': '-0.249', 'Platelets': '-0.180', 'Erythrocytes': '-0.123', 'Hematopoietic stem cells': '-0.320', 'B-cells (Spleen)': '0.551', 'NK-cells (Spleen)': '0.395', 'Amygdala excitatory': '39.5', 'Cerebellar inhibitory': '26.5', 'Cge interneuron': '39.4', 'Deep-layer corticothalamic and 6b': '39.2', 'Deep-layer intratelencephalic': '35.2', 'Deep-layer near-projecting': '36.9', 'Eccentric medium spiny neuron': '41.9', 'Hippocampal ca1-3': '42.3', 'Hippocampal ca4': '33.9', 'Hippocampal dentate gyrus': '63.5', 'Lamp5-lhx6 and chandelier': '39.6', 'Lower rhombic lip': '51.0', 'Mammillary body': '43.9', 'Medium spiny neuron': '41.8', 'Mge interneuron': '43.1', 'Midbrain-derived inhibitory': '32.2', 'Miscellaneous': '37.1', 'Splatter': '37.5', 'Thalamic excitatory': '40.5', 'Upper rhombic lip': '76.4', 'Upper-layer intratelencephalic': '51.0', 'Astrocyte': '47.0', 'Bergmann glia': '43.8', 'Central nervous system macrophage': '120.6', 'Choroid plexus epithelial cell': '48.6', 'Committed oligodendrocyte precursor': '74.8', 'Ependymal cell': '58.9', 'Oligodendrocyte': '126.0', 'Oligodendrocyte precursor cell': '79.8', 'Endothelial cell': '95.2', 'Pericyte': '128.2', 'Vascular associated smooth muscle cell': '64.2', 'Fibroblast': '95.6', 'Leukocyte': '55.0', 'Basophil': '54.4', 'Eosinophil': '28.5', 'Neutrophil': '72.0', 'Classical monocyte': '12.3', 'Non-classical monocyte': '18.8', 'Intermediate monocyte': '37.7', 'T-reg': '46.1', 'GdT-cell': '19.0', 'MAIT T-cell': '47.1', 'Memory CD4 T-cell': '25.6', 'Naive CD4 T-cell': '25.0', 'Memory CD8 T-cell': '25.2', 'Naive CD8 T-cell': '17.0', 'Memory B-cell': '46.6', 'Naive B-cell': '39.5', 'Plasmacytoid DC': '80.5', 'Myeloid DC': '52.8', 'NK-cell': '19.2', 'Total PBMC': '44.5', 'Vd2 gdTCR': '40.7', 'Memory CD4 T-cell Th1\\/Th17': '24.1', 'Memory CD4 T-cell Th17': '25.0', 'Memory CD4 T-cell Th2': '25.5', 'Non-Vd2 gdTCR': '47.4', 'Memory CD4 T-cell Th1': '21.8', 'Memory CD4 T-cell TFH': '20.7', 'Terminal effector memory CD4 T-cell': '46.1', 'Central memory CD8 T-cell': '49.3', 'Effector memory CD8 T-cell': '51.7', 'Terminal effector memory CD8 T-cell': '51.8', 'Non-switched memory B-cell': '73.2', 'Plasmablast': '37.4', 'Switched memory B-cell': '72.4', 'Exhausted memory B-cell': '60.5', 'Progenitor cell': '65.8', 'Memory T-reg': '19.8', 'Naive CD4 T-cell activated': '16.7', 'Naive CD8 T-cell activated': '12.1', 'Naive T-reg': '22.9'}
null
{'Adipose Tissue': 9.431014950166112, 'Adrenal Gland': 7.125096899224807, 'Bladder': 10.608285714285714, 'Blood': 4.998763509149623, 'Blood Vessel': 11.487531086142322, 'Brain': 6.6067780847842545, 'Breast': 10.684084967320262, 'Cervix Uteri': 12.674736842105265, 'Colon': 10.200605905006418, 'Esophagus': 13.939683737024222, 'Fallopian Tube': 13.330666666666666, 'Heart': 3.9377188153310105, 'Kidney': 6.1288426966292135, 'Liver': 3.348150442477876, 'Lung': 14.11987197231834, 'Muscle': 6.039047322540473, 'Nerve': 13.861156704361877, 'Ovary': 12.146372222222224, 'Pancreas': 3.732479573170732, 'Pituitary': 10.571583038869257, 'Prostate': 14.106820408163264, 'Salivary Gland': 10.103123456790122, 'Skin': 14.289758430071862, 'Small Intestine': 11.249764705882354, 'Spleen': 12.711033195020748, 'Stomach': 7.44783008356546, 'Testis': 37.17598337950139, 'Thyroid': 13.078012251148545, 'Uterus': 13.399830985915491, 'Vagina': 13.23275}
VCP
MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGSFRFPSGNQGGAGPSQGSGGGTGGSVYTEDNDDDLYG
Homo sapiens
Cytoplasm, cytosol, Endoplasmic reticulum, Nucleus, Cytoplasm, Stress granule
Low tissue specificity
{'Ciliated cells': '114.5', 'Basal respiratory cells': '146.0', 'Club cells': '118.3', 'Ionocytes': '95.4', 'Mucus glandular cells': '129.7', 'Serous glandular cells': '134.1', 'Gastric mucus-secreting cells': '131.5', 'Proximal enterocytes': '75.7', 'Paneth cells': '61.1', 'Distal enterocytes': '102.0', 'Intestinal goblet cells': '76.4', 'Exocrine glandular cells': '-0.609', 'Basal prostatic cells': '96.7', 'Prostatic glandular cells': '147.2', 'Breast glandular cells': '-0.106', 'Breast myoepithelial cells': '-0.170', 'Glandular and luminal cells': '107.9', 'Secretory cells': '86.2', 'Basal keratinocytes': '125.2', 'Suprabasal keratinocytes': '175.6', 'Basal squamous epithelial cells': '104.4', 'Squamous epithelial cells': '128.4', 'Alveolar cells type 1': '0.005', 'Alveolar cells type 2': '0.140', 'Salivary duct cells': '115.6', 'Ductal cells': '0.606', 'Hepatocytes': '0.586', 'Cholangiocytes': '51.5', 'Proximal tubular cells': '0.286', 'Distal tubular cells': '52.2', 'Collecting duct cells': '64.2', 'Mesothelial cells': '0.067', 'Sertoli cells': '0.357', 'Granulosa cells': '56.1', 'Enteroendocrine cells': '74.1', 'Pancreatic endocrine cells': '195.3', 'Leydig cells': '0.399', 'Excitatory neurons': '26.5', 'Inhibitory neurons': '26.5', 'Cone photoreceptor cells': '134.2', 'Rod photoreceptor cells': '99.2', 'Bipolar cells': '103.0', 'Horizontal cells': '79.9', 'Astrocytes': '21.7', 'Oligodendrocyte precursor cells': '17.5', 'Oligodendrocytes': '29.3', 'Microglial cells': '16.1', 'Muller glia cells': '91.5', 'Schwann cells': '-0.003', 'Spermatogonia': '0.717', 'Spermatocytes': '0.680', 'Early spermatids': '-0.138', 'Late spermatids': '-0.353', 'Oocytes': '35.3', 'Cytotrophoblasts': '274.8', 'Syncytiotrophoblasts': '595.8', 'Extravillous trophoblasts': '165.8', 'Endothelial cells': '118.0', 'Lymphatic endothelial cells': '108.3', 'Cardiomyocytes': '0.711', 'Skeletal myocytes': '-0.258', 'Smooth muscle cells': '100.3', 'Adipocytes': '84.0', 'Melanocytes': '0.336', 'Fibroblasts': '123.9', 'Peritubular cells': '0.224', 'Endometrial stromal cells': '88.7', 'Ovarian stromal cells': '59.0', 'Undifferentiated cells': '71.0', 'T-cells': '104.2', 'B-cells': '119.6', 'Plasma cells': '262.4', 'Nk-cells': '79.3', 'Granulocytes': '112.6', 'Monocytes': '85.6', 'Macrophages': '98.6', 'Hofbauer cells': '117.0', 'Kupffer cells': '79.0', 'Dendritic cells': '103.5', 'Langerhans cells': '0.267', 'Erythroid cells': '-0.132', 'Adipocytes (Subcutaneous)': '0.313', 'Adipocytes (Visceral)': '0.274', 'Breast glandular cells (progenitors)': '-0.146', 'Adipocytes (Breast)': '0.374', 'Colon enterocytes': '-0.084', 'Colon enteroendocrine cells': '0.116', 'Enteric glia cells': '-0.323', 'Mitotic cells (Colon)': '0.001', 'Mitotic cells (Heart)': '0.482', 'Podocytes': '-0.088', 'Ascending Loop of Henle cells': '0.315', 'Intercalated cells': '-0.062', 'Cholangiocyte': '0.298', 'NK-cells (Liver)': '-0.364', 'Respiratory ciliated cells': '-0.114', 'Mitotic cells (Lung)': '0.168', 'NK-cells (Lung)': '0.018', 'B-cells (Lung)': '-0.130', 'Alpha cells': '0.365', 'Beta cells': '0.215', 'Prostate glandular cells': '0.116', 'Prostate basal glandular cells': '0.104', 'Urothelial cells': '-0.082', 'Keratinocyte (other)': '0.248', 'Keratinocyte (granular)': '0.008', 'Hair cortex cells': '0.275', 'Inner root sheath cells': '0.305', 'Outer root sheath cells': '0.269', 'Sebaceous gland cells': '0.127', 'Eccrine sweat gland cells': '-0.169', 'Adipocytes (Skin)': '-0.124', 'Mitotic cells (Skin)': '0.383', 'Parietal cells': '-0.555', 'Chief cells': '-0.502', 'Gastric mucous cells': '-0.136', 'Gastric enteroendocrine cells': '-0.390', 'Mitotic cells (Stomach)': '0.319', 'Parafollicular cells': '0.083', 'Thyroid glandular cells': '0.301', 'Mitotic cells (Thyroid)': '0.009', 'Adrenal cortex cells': '0.487', 'Adrenal medulla cells': '0.047', 'Mitotic cells (Adrenal gland)': '0.417', 'Minor salivary glandular cells': '0.226', 'Minor salivary gland ductal cells': '-0.224', 'Minor salivary gland basal cells': '0.520', 'Mitotic cells (Minor salivary gland)': '0.595', 'Adipocytes (Minor salivary gland)': '0.086', 'Somatotropes': '0.120', 'Lactotropes': '0.186', 'Gonadotropes': '0.276', 'Corticotropes': '0.068', 'Thyrotropes': '0.272', 'Undifferentiated cells (Pituitary gland)': '0.013', 'Mitotic cells (Spleen)': '0.158', 'Platelets': '0.073', 'Erythrocytes': '-0.090', 'Hematopoietic stem cells': '0.016', 'B-cells (Spleen)': '0.127', 'NK-cells (Spleen)': '-0.070', 'Amygdala excitatory': '47.1', 'Cerebellar inhibitory': '52.4', 'Cge interneuron': '53.7', 'Deep-layer corticothalamic and 6b': '51.0', 'Deep-layer intratelencephalic': '52.9', 'Deep-layer near-projecting': '54.1', 'Eccentric medium spiny neuron': '48.4', 'Hippocampal ca1-3': '49.5', 'Hippocampal ca4': '68.6', 'Hippocampal dentate gyrus': '56.7', 'Lamp5-lhx6 and chandelier': '55.2', 'Lower rhombic lip': '58.5', 'Mammillary body': '50.4', 'Medium spiny neuron': '44.1', 'Mge interneuron': '50.2', 'Midbrain-derived inhibitory': '58.4', 'Miscellaneous': '44.9', 'Splatter': '58.9', 'Thalamic excitatory': '53.9', 'Upper rhombic lip': '55.9', 'Upper-layer intratelencephalic': '42.3', 'Astrocyte': '50.0', 'Bergmann glia': '54.2', 'Central nervous system macrophage': '55.5', 'Choroid plexus epithelial cell': '64.6', 'Committed oligodendrocyte precursor': '55.8', 'Ependymal cell': '43.0', 'Oligodendrocyte': '57.0', 'Oligodendrocyte precursor cell': '43.3', 'Endothelial cell': '98.3', 'Pericyte': '76.1', 'Vascular associated smooth muscle cell': '68.7', 'Fibroblast': '56.4', 'Leukocyte': '62.9', 'Basophil': '181.0', 'Eosinophil': '75.1', 'Neutrophil': '146.1', 'Classical monocyte': '188.6', 'Non-classical monocyte': '145.3', 'Intermediate monocyte': '83.1', 'T-reg': '81.5', 'GdT-cell': '58.8', 'MAIT T-cell': '76.7', 'Memory CD4 T-cell': '59.2', 'Naive CD4 T-cell': '108.8', 'Memory CD8 T-cell': '65.4', 'Naive CD8 T-cell': '100.1', 'Memory B-cell': '59.3', 'Naive B-cell': '92.6', 'Plasmacytoid DC': '126.2', 'Myeloid DC': '90.1', 'NK-cell': '195.5', 'Total PBMC': '89.7', 'Vd2 gdTCR': '88.3', 'Memory CD4 T-cell Th1\\/Th17': '140.6', 'Memory CD4 T-cell Th17': '154.7', 'Memory CD4 T-cell Th2': '162.3', 'Non-Vd2 gdTCR': '104.3', 'Memory CD4 T-cell Th1': '152.2', 'Memory CD4 T-cell TFH': '161.4', 'Terminal effector memory CD4 T-cell': '111.5', 'Central memory CD8 T-cell': '84.3', 'Effector memory CD8 T-cell': '104.2', 'Terminal effector memory CD8 T-cell': '109.1', 'Non-switched memory B-cell': '103.8', 'Plasmablast': '312.5', 'Switched memory B-cell': '117.8', 'Exhausted memory B-cell': '117.4', 'Progenitor cell': '98.7', 'Memory T-reg': '203.7', 'Naive CD4 T-cell activated': '271.6', 'Naive CD8 T-cell activated': '275.9', 'Naive T-reg': '116.5'}
3EBB, 3HU1, 3HU2, 3HU3, 3QC8, 3QQ7, 3QQ8, 3QWZ, 3TIW, 4KDI, 4KDL, 4KLN, 4KO8, 4KOD, 4P0A, 5B6C, 5C18, 5C19, 5C1A, 5C1B, 5DYG, 5DYI, 5EPP, 5FTJ, 5FTK, 5FTL, 5FTM, 5FTN, 5GLF, 5IFS, 5IFW, 5KIW, 5KIY, 5X4L, 6G2V, 6G2W, 6G2X, 6G2Y, 6G2Z, 6G30, 6HD0, 6MCK, 7BP8, 7BP9, 7BPA, 7BPB, 7JY5, 7K56, 7K57, 7K59, 7L5W, 7L5X, 7LMY, 7LMZ, 7LN0, 7LN1, 7LN2, 7LN3, 7LN4, 7LN5, 7LN6, 7MDM, 7MDO, 7MHS, 7OAT, 7PUX, 7R7S, 7R7T, 7R7U, 7RL6, 7RL7, 7RL9, 7RLA, 7RLB, 7RLC, 7RLD, 7RLF, 7RLG, 7RLH, 7RLI, 7RLJ, 7VCS, 7VCT, 7VCU, 7VCV, 7VCX, 7Y4W, 7Y53, 7Y59, 8B5R, 8FCL, 8FCM, 8FCN, 8FCO, 8FCP, 8FCQ, 8FCR, 8FCT, 8HL7, 8HRZ, 8KG2, 8OOI, 8PQX, 8R0E, 8RS9, 8RSB, 8RSC, 8VKU, 8VLS, 8VOV
{'Adipose Tissue': 145.10239202657806, 'Adrenal Gland': 167.8136434108527, 'Bladder': 156.3761904761905, 'Blood': 89.89988482238967, 'Blood Vessel': 166.62775280898876, 'Brain': 65.75532929598788, 'Breast': 136.64884531590414, 'Cervix Uteri': 158.2736842105263, 'Colon': 116.618729139923, 'Esophagus': 145.54085121107266, 'Fallopian Tube': 159.41111111111113, 'Heart': 100.82308594657374, 'Kidney': 77.32325842696629, 'Liver': 78.63217699115044, 'Lung': 171.05686851211073, 'Muscle': 204.81033623910335, 'Nerve': 160.07423263327948, 'Ovary': 138.83561111111112, 'Pancreas': 48.3807012195122, 'Pituitary': 143.51787985865724, 'Prostate': 139.25844897959183, 'Salivary Gland': 137.46104938271606, 'Skin': 175.70694306246546, 'Small Intestine': 120.7403743315508, 'Spleen': 151.39697095435685, 'Stomach': 106.11894150417828, 'Testis': 143.0014681440443, 'Thyroid': 154.06546707503827, 'Uterus': 175.02, 'Vagina': 151.60782051282052}
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[1.0, 1.0, 1.0, 1.0, 1.0, 0.82, 0.97, 0.81, 0.87, 0.68, 0.57, 0.81, 0.73, 0.42, 0.48, 0.89, 0.79, 0.54, 0.82, 0.86, 0.8, 0.69, 0.4, 0.24, 0.66, 0.01, 0.36, 0.02, 0.23, 0.37, 0.4, 0.62, 0.39, 0.53, 0.28, 0.13, 0.07, 0.12, 0.0, 0.11, 0.0, 0.03, 0.42, 0.56, 0.1, 0.03, 0.59, 0.55, 0.13, 0.78, 0.05, 0.7, 0.74, 0.52, 0.33, 0.18, 0.0, 0.1, 0.0, 0.32, 0.33, 0.44, 0.64, 0.92, 0.32, 0.22, 0.02, 0.04, 0.03, 0.2, 0.0, 0.24, 0.38, 0.16, 0.85, 0.63, 0.07, 0.51, 0.46, 0.7, 0.35, 0.0, 0.15, 0.01, 0.16, 0.11, 0.06, 0.02, 0.08, 0.16, 0.11, 0.0, 0.22, 0.06, 0.22, 0.08, 0.32, 0.09, 0.47, 0.02, 0.23, 0.02, 0.41, 0.54, 0.09, 0.87, 0.76, 0.13, 0.69, 0.57, 0.04, 0.67, 0.61, 0.02, 0.3, 0.01, 0.1, 0.08, 0.0, 0.36, 0.55, 0.02, 0.09, 0.75, 0.49, 0.19, 0.43, 0.61, 0.39, 0.19, 0.32, 0.45, 0.09, 0.02, 0.0, 0.45, 0.54, 0.16, 0.08, 0.71, 0.8, 0.31, 0.45, 0.13, 0.05, 0.06, 0.23, 0.43, 0.31, 0.1, 0.09, 0.06, 0.13, 0.07, 0.4, 0.14, 0.06, 0.25, 0.25, 0.16, 0.0, 0.01, 0.01, 0.13, 0.02, 0.38, 0.48, 0.05, 0.28, 0.27, 0.62, 0.51, 0.27, 0.01, 0.11, 0.02, 0.08, 0.7, 0.73, 0.1, 0.48, 0.2, 0.5, 0.28, 0.84, 0.67, 0.87, 0.43, 0.2, 0.83, 0.2, 0.48, 0.98, 0.46, 0.08, 0.45, 0.2, 0.13, 0.57, 0.42, 0.21, 0.0, 0.03, 0.38, 0.32, 0.14, 0.22, 0.31, 0.09, 0.71, 0.82, 0.29, 0.09, 0.4, 0.47, 0.0, 0.17, 0.61, 0.15, 0.0, 0.24, 0.4, 0.09, 0.13, 0.33, 0.52, 0.35, 0.7, 0.47, 0.23, 0.85, 0.82, 0.64, 0.7, 0.58, 0.76, 0.36, 0.16, 0.19, 0.0, 0.0, 0.0, 0.0, 0.23, 0.11, 0.08, 0.48, 0.35, 0.12, 0.3, 0.09, 0.3, 0.37, 0.01, 0.0, 0.38, 0.0, 0.0, 0.04, 0.28, 0.07, 0.1, 0.48, 0.12, 0.3, 0.25, 0.23, 0.44, 0.04, 0.4, 0.0, 0.39, 0.53, 0.07, 0.3, 0.78, 0.38, 0.72, 0.21, 0.58, 0.48, 0.01, 0.15, 0.33, 0.27, 0.0, 0.34, 0.56, 0.01, 0.07, 0.51, 0.41, 0.0, 0.41, 0.78, 0.42, 0.42, 0.41, 0.0, 0.0, 0.0, 0.0, 0.0, 0.22, 0.46, 0.0, 0.23, 0.31, 0.0, 0.0, 0.2, 0.35, 0.5, 0.9, 0.69, 0.03, 0.87, 0.28, 0.74, 0.39, 0.33, 0.48, 0.47, 0.03, 0.03, 0.41, 0.2, 0.01, 0.08, 0.62, 0.16, 0.0, 0.48, 0.6, 0.12, 0.63, 0.51, 0.88, 0.1, 0.39, 0.13, 0.04, 0.0, 0.0, 0.0, 0.01, 0.01, 0.41, 0.71, 0.22, 0.57, 0.19, 0.02, 0.06, 0.57, 0.25, 0.0, 0.37, 0.74, 0.85, 0.24, 0.17, 0.01, 0.31, 0.56, 0.4, 0.01, 0.48, 0.02, 0.38, 0.27, 0.1, 0.65, 0.32, 0.61, 0.02, 0.05, 0.23, 0.16, 0.09, 0.0, 0.47, 0.18, 0.4, 0.07, 0.22, 0.31, 0.19, 0.43, 0.32, 0.26, 0.96, 0.55, 0.19, 0.43, 0.12, 0.59, 0.36, 0.0, 0.01, 0.58, 0.52, 0.0, 0.22, 0.03, 0.05, 0.01, 0.18, 0.45, 0.09, 0.0, 0.21, 0.49, 0.02, 0.01, 0.5, 0.31, 0.0, 0.07, 0.43, 0.16, 0.03, 0.27, 0.45, 0.53, 0.31, 0.48, 0.88, 0.72, 0.2, 0.56, 0.74, 0.86, 0.59, 0.92, 0.44, 0.4, 0.41, 0.02, 0.52, 0.32, 0.18, 0.28, 0.48, 0.02, 0.3, 0.0, 0.33, 0.03, 0.53, 0.01, 0.0, 0.49, 0.34, 0.02, 0.18, 0.74, 0.65, 0.25, 0.68, 0.2, 0.32, 0.27, 0.14, 0.64, 0.82, 0.25, 0.66, 0.07, 0.41, 0.22, 0.02, 0.82, 0.19, 0.3, 0.12, 0.67, 0.31, 0.09, 0.14, 0.09, 0.14, 0.59, 0.64, 0.07, 0.09, 0.56, 0.37, 0.0, 0.26, 0.46, 0.17, 0.03, 0.12, 0.45, 0.1, 0.3, 0.6, 0.47, 0.47, 0.67, 0.6, 0.24, 0.79, 0.85, 0.7, 0.75, 0.61, 0.83, 0.29, 0.22, 0.22, 0.02, 0.04, 0.03, 0.0, 0.05, 0.0, 0.02, 0.4, 0.38, 0.1, 0.23, 0.05, 0.35, 0.45, 0.0, 0.0, 0.22, 0.01, 0.0, 0.0, 0.13, 0.41, 0.13, 0.66, 0.03, 0.12, 0.01, 0.01, 0.37, 0.02, 0.51, 0.01, 0.4, 0.4, 0.02, 0.42, 0.73, 0.29, 0.74, 0.76, 0.91, 0.5, 0.16, 0.33, 0.49, 0.21, 0.01, 0.39, 0.39, 0.05, 0.0, 0.31, 0.18, 0.0, 0.21, 0.53, 0.06, 0.42, 0.32, 0.0, 0.0, 0.0, 0.0, 0.04, 0.17, 0.47, 0.05, 0.2, 0.39, 0.06, 0.01, 0.54, 0.44, 0.63, 0.88, 0.94, 0.89, 0.99, 0.57, 0.88, 0.65, 0.38, 0.33, 0.18, 0.17, 0.33, 0.57, 0.02, 0.04, 0.42, 0.11, 0.09, 0.07, 0.59, 0.12, 0.04, 0.48, 0.62, 0.04, 0.5, 0.4, 0.9, 0.51, 0.34, 0.09, 0.1, 0.02, 0.01, 0.0, 0.03, 0.01, 0.29, 0.5, 0.07, 0.75, 0.21, 0.08, 0.09, 0.6, 0.16, 0.07, 0.26, 0.66, 0.88, 0.3, 0.15, 0.02, 0.25, 0.27, 0.2, 0.01, 0.27, 0.0, 0.39, 0.21, 0.14, 0.54, 0.44, 0.8, 0.16, 0.05, 0.14, 0.33, 0.13, 0.02, 0.47, 0.18, 0.32, 0.1, 0.51, 0.91, 0.33, 0.51, 0.31, 0.11, 0.94, 0.39, 0.15, 0.51, 0.16, 0.47, 0.56, 0.09, 0.0, 0.59, 0.57, 0.01, 0.63, 0.15, 0.09, 0.01, 0.17, 0.45, 0.08, 0.0, 0.3, 0.49, 0.02, 0.06, 0.48, 0.36, 0.0, 0.29, 0.58, 0.24, 0.07, 0.49, 0.6, 0.32, 0.18, 0.48, 0.53, 0.29, 0.53, 0.46, 0.65, 0.45, 0.49, 0.67, 0.56, 0.48, 0.67, 0.76, 0.57, 0.79, 0.79, 0.69, 0.85, 0.82, 0.8, 0.89, 0.69, 0.76, 0.55, 0.47, 0.1, 0.59, 0.51, 0.04, 0.32, 0.45, 0.51, 0.05, 0.03, 0.57, 0.35, 0.01, 0.25, 0.78, 0.54, 0.28, 0.84, 0.4, 0.62, 0.04, 0.44, 0.52, 0.67, 0.36, 0.2, 0.59, 0.64, 0.13, 0.48, 0.57, 0.26, 0.08, 0.58, 0.6, 0.17, 0.68, 0.76, 0.69, 0.58, 0.71, 0.94, 0.99, 0.92, 0.75, 0.92, 0.79, 0.89, 0.93, 0.91, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0]
RING finger
null
null
null
VCP,AKT1,MDM2,SQSTM1, TRAF6,IKBKG
MDM2, AKT1, TRAF6, IKBKG
29
null
null
null
null
79.775479
0.523071
82.822295
0.361725
750
O60858
Q00987
21333377
UbiNet, UbiBrowser, 31181401
TRIM13
MELLEEDLTCPICCSLFDDPRVLPCSHNFCKKCLEGILEGSVRNSLWRPAPFKCPTCRKETSATGINSLQVNYSLKGIVEKYNKIKISPKMPVCKGHLGQPLNIFCLTDMQLICGICATRGEHTKHVFCSIEDAYAQERDAFESLFQSFETWRRGDALSRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPEINKLNTILQEQRMAFNIAEAFKDVSEPIVFLQQMQEFREKIKVIKETPLPPSNLPASPLMKNFDTSQWEDIKLVDVDKLSLPQDTGTFISKIPWSFYKLFLLILLLGLVIVFGPTMFLEWSLFDDLATWKGCLSNFSSYLTKTADFIEQSVFYWEQVTDGFFIFNERFKNFTLVVLNNVAEFVCKYKLL
Homo sapiens
Endoplasmic reticulum membrane
Low tissue specificity
{'Ciliated cells': '35.7', 'Basal respiratory cells': '46.2', 'Club cells': '36.4', 'Ionocytes': '45.3', 'Mucus glandular cells': '19.6', 'Serous glandular cells': '21.6', 'Gastric mucus-secreting cells': '13.6', 'Proximal enterocytes': '19.2', 'Paneth cells': '22.6', 'Distal enterocytes': '29.5', 'Intestinal goblet cells': '26.4', 'Exocrine glandular cells': '-0.691', 'Basal prostatic cells': '38.4', 'Prostatic glandular cells': '57.3', 'Breast glandular cells': '0.654', 'Breast myoepithelial cells': '0.557', 'Glandular and luminal cells': '14.3', 'Secretory cells': '25.7', 'Basal keratinocytes': '24.6', 'Suprabasal keratinocytes': '37.3', 'Basal squamous epithelial cells': '21.3', 'Squamous epithelial cells': '30.7', 'Alveolar cells type 1': '0.156', 'Alveolar cells type 2': '0.058', 'Salivary duct cells': '18.9', 'Ductal cells': '0.609', 'Hepatocytes': '0.096', 'Cholangiocytes': '21.0', 'Proximal tubular cells': '0.335', 'Distal tubular cells': '12.3', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.408', 'Sertoli cells': '-0.535', 'Granulosa cells': '46.9', 'Enteroendocrine cells': '31.8', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '-0.547', 'Excitatory neurons': '29.5', 'Inhibitory neurons': '28.3', 'Cone photoreceptor cells': '15.3', 'Rod photoreceptor cells': '56.5', 'Bipolar cells': '22.0', 'Horizontal cells': '15.7', 'Astrocytes': '19.8', 'Oligodendrocyte precursor cells': '42.9', 'Oligodendrocytes': '53.5', 'Microglial cells': '34.0', 'Muller glia cells': '13.8', 'Schwann cells': '0.150', 'Spermatogonia': '-0.307', 'Spermatocytes': '0.084', 'Early spermatids': '0.882', 'Late spermatids': '0.649', 'Oocytes': '26.5', 'Cytotrophoblasts': '33.3', 'Syncytiotrophoblasts': '33.7', 'Extravillous trophoblasts': '16.6', 'Endothelial cells': '29.9', 'Lymphatic endothelial cells': '18.0', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '-0.188', 'Smooth muscle cells': '26.6', 'Adipocytes': '31.3', 'Melanocytes': '0.133', 'Fibroblasts': '24.1', 'Peritubular cells': '-0.360', 'Endometrial stromal cells': '23.3', 'Ovarian stromal cells': '27.9', 'Undifferentiated cells': '22.8', 'T-cells': '25.5', 'B-cells': '37.6', 'Plasma cells': '11.7', 'Nk-cells': '26.4', 'Granulocytes': '41.3', 'Monocytes': '32.1', 'Macrophages': '22.1', 'Hofbauer cells': '17.9', 'Kupffer cells': '16.8', 'Dendritic cells': '30.3', 'Langerhans cells': '0.265', 'Erythroid cells': '0.064', 'Adipocytes (Subcutaneous)': '-0.207', 'Adipocytes (Visceral)': '-0.380', 'Breast glandular cells (progenitors)': '0.416', 'Adipocytes (Breast)': '-0.618', 'Colon enterocytes': '0.048', 'Colon enteroendocrine cells': '0.141', 'Enteric glia cells': '-0.121', 'Mitotic cells (Colon)': '0.151', 'Mitotic cells (Heart)': '0.485', 'Podocytes': '-0.163', 'Ascending Loop of Henle cells': '0.354', 'Intercalated cells': '-0.112', 'Cholangiocyte': '0.172', 'NK-cells (Liver)': '-0.079', 'Respiratory ciliated cells': '0.210', 'Mitotic cells (Lung)': '-0.007', 'NK-cells (Lung)': '0.157', 'B-cells (Lung)': '0.054', 'Alpha cells': '0.429', 'Beta cells': '0.264', 'Prostate glandular cells': '0.412', 'Prostate basal glandular cells': '0.532', 'Urothelial cells': '0.131', 'Keratinocyte (other)': '0.381', 'Keratinocyte (granular)': '-0.008', 'Hair cortex cells': '-0.340', 'Inner root sheath cells': '-0.257', 'Outer root sheath cells': '-0.142', 'Sebaceous gland cells': '0.001', 'Eccrine sweat gland cells': '-0.215', 'Adipocytes (Skin)': '-0.313', 'Mitotic cells (Skin)': '0.144', 'Parietal cells': '-0.382', 'Chief cells': '-0.347', 'Gastric mucous cells': '-0.142', 'Gastric enteroendocrine cells': '-0.174', 'Mitotic cells (Stomach)': '0.162', 'Parafollicular cells': '-0.014', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '-0.007', 'Adrenal cortex cells': '0.320', 'Adrenal medulla cells': '0.018', 'Mitotic cells (Adrenal gland)': '0.240', 'Minor salivary glandular cells': '0.254', 'Minor salivary gland ductal cells': '0.032', 'Minor salivary gland basal cells': '0.575', 'Mitotic cells (Minor salivary gland)': '0.491', 'Adipocytes (Minor salivary gland)': '0.133', 'Somatotropes': '-0.167', 'Lactotropes': '-0.121', 'Gonadotropes': '-0.119', 'Corticotropes': '0.059', 'Thyrotropes': '0.127', 'Undifferentiated cells (Pituitary gland)': '0.293', 'Mitotic cells (Spleen)': '-0.249', 'Platelets': '-0.180', 'Erythrocytes': '-0.123', 'Hematopoietic stem cells': '-0.320', 'B-cells (Spleen)': '0.551', 'NK-cells (Spleen)': '0.395', 'Amygdala excitatory': '39.5', 'Cerebellar inhibitory': '26.5', 'Cge interneuron': '39.4', 'Deep-layer corticothalamic and 6b': '39.2', 'Deep-layer intratelencephalic': '35.2', 'Deep-layer near-projecting': '36.9', 'Eccentric medium spiny neuron': '41.9', 'Hippocampal ca1-3': '42.3', 'Hippocampal ca4': '33.9', 'Hippocampal dentate gyrus': '63.5', 'Lamp5-lhx6 and chandelier': '39.6', 'Lower rhombic lip': '51.0', 'Mammillary body': '43.9', 'Medium spiny neuron': '41.8', 'Mge interneuron': '43.1', 'Midbrain-derived inhibitory': '32.2', 'Miscellaneous': '37.1', 'Splatter': '37.5', 'Thalamic excitatory': '40.5', 'Upper rhombic lip': '76.4', 'Upper-layer intratelencephalic': '51.0', 'Astrocyte': '47.0', 'Bergmann glia': '43.8', 'Central nervous system macrophage': '120.6', 'Choroid plexus epithelial cell': '48.6', 'Committed oligodendrocyte precursor': '74.8', 'Ependymal cell': '58.9', 'Oligodendrocyte': '126.0', 'Oligodendrocyte precursor cell': '79.8', 'Endothelial cell': '95.2', 'Pericyte': '128.2', 'Vascular associated smooth muscle cell': '64.2', 'Fibroblast': '95.6', 'Leukocyte': '55.0', 'Basophil': '54.4', 'Eosinophil': '28.5', 'Neutrophil': '72.0', 'Classical monocyte': '12.3', 'Non-classical monocyte': '18.8', 'Intermediate monocyte': '37.7', 'T-reg': '46.1', 'GdT-cell': '19.0', 'MAIT T-cell': '47.1', 'Memory CD4 T-cell': '25.6', 'Naive CD4 T-cell': '25.0', 'Memory CD8 T-cell': '25.2', 'Naive CD8 T-cell': '17.0', 'Memory B-cell': '46.6', 'Naive B-cell': '39.5', 'Plasmacytoid DC': '80.5', 'Myeloid DC': '52.8', 'NK-cell': '19.2', 'Total PBMC': '44.5', 'Vd2 gdTCR': '40.7', 'Memory CD4 T-cell Th1\\/Th17': '24.1', 'Memory CD4 T-cell Th17': '25.0', 'Memory CD4 T-cell Th2': '25.5', 'Non-Vd2 gdTCR': '47.4', 'Memory CD4 T-cell Th1': '21.8', 'Memory CD4 T-cell TFH': '20.7', 'Terminal effector memory CD4 T-cell': '46.1', 'Central memory CD8 T-cell': '49.3', 'Effector memory CD8 T-cell': '51.7', 'Terminal effector memory CD8 T-cell': '51.8', 'Non-switched memory B-cell': '73.2', 'Plasmablast': '37.4', 'Switched memory B-cell': '72.4', 'Exhausted memory B-cell': '60.5', 'Progenitor cell': '65.8', 'Memory T-reg': '19.8', 'Naive CD4 T-cell activated': '16.7', 'Naive CD8 T-cell activated': '12.1', 'Naive T-reg': '22.9'}
null
{'Adipose Tissue': 9.431014950166112, 'Adrenal Gland': 7.125096899224807, 'Bladder': 10.608285714285714, 'Blood': 4.998763509149623, 'Blood Vessel': 11.487531086142322, 'Brain': 6.6067780847842545, 'Breast': 10.684084967320262, 'Cervix Uteri': 12.674736842105265, 'Colon': 10.200605905006418, 'Esophagus': 13.939683737024222, 'Fallopian Tube': 13.330666666666666, 'Heart': 3.9377188153310105, 'Kidney': 6.1288426966292135, 'Liver': 3.348150442477876, 'Lung': 14.11987197231834, 'Muscle': 6.039047322540473, 'Nerve': 13.861156704361877, 'Ovary': 12.146372222222224, 'Pancreas': 3.732479573170732, 'Pituitary': 10.571583038869257, 'Prostate': 14.106820408163264, 'Salivary Gland': 10.103123456790122, 'Skin': 14.289758430071862, 'Small Intestine': 11.249764705882354, 'Spleen': 12.711033195020748, 'Stomach': 7.44783008356546, 'Testis': 37.17598337950139, 'Thyroid': 13.078012251148545, 'Uterus': 13.399830985915491, 'Vagina': 13.23275}
MDM2
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Homo sapiens
Nucleus, nucleoplasm, Cytoplasm, Nucleus, nucleolus, Nucleus
Low tissue specificity
{'Ciliated cells': '157.9', 'Basal respiratory cells': '45.2', 'Club cells': '66.6', 'Ionocytes': '58.5', 'Mucus glandular cells': '57.6', 'Serous glandular cells': '27.7', 'Gastric mucus-secreting cells': '34.8', 'Proximal enterocytes': '14.3', 'Paneth cells': '20.9', 'Distal enterocytes': '17.8', 'Intestinal goblet cells': '20.8', 'Exocrine glandular cells': '-0.511', 'Basal prostatic cells': '63.2', 'Prostatic glandular cells': '63.2', 'Breast glandular cells': '0.007', 'Breast myoepithelial cells': '-0.198', 'Glandular and luminal cells': '51.5', 'Secretory cells': '77.2', 'Basal keratinocytes': '28.0', 'Suprabasal keratinocytes': '33.4', 'Basal squamous epithelial cells': '35.2', 'Squamous epithelial cells': '59.5', 'Alveolar cells type 1': '-0.093', 'Alveolar cells type 2': '0.175', 'Salivary duct cells': '39.4', 'Ductal cells': '0.275', 'Hepatocytes': '-0.002', 'Cholangiocytes': '26.7', 'Proximal tubular cells': '0.210', 'Distal tubular cells': '12.3', 'Collecting duct cells': '31.1', 'Mesothelial cells': '0.134', 'Sertoli cells': '0.415', 'Granulosa cells': '16.6', 'Enteroendocrine cells': '20.9', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.561', 'Excitatory neurons': '27.8', 'Inhibitory neurons': '31.5', 'Cone photoreceptor cells': '25.5', 'Rod photoreceptor cells': '33.3', 'Bipolar cells': '22.2', 'Horizontal cells': '26.4', 'Astrocytes': '24.8', 'Oligodendrocyte precursor cells': '24.1', 'Oligodendrocytes': '66.9', 'Microglial cells': '35.8', 'Muller glia cells': '25.7', 'Schwann cells': '0.024', 'Spermatogonia': '0.471', 'Spermatocytes': '0.218', 'Early spermatids': '-0.431', 'Late spermatids': '-0.672', 'Oocytes': '27.2', 'Cytotrophoblasts': '45.4', 'Syncytiotrophoblasts': '96.5', 'Extravillous trophoblasts': '28.1', 'Endothelial cells': '25.2', 'Lymphatic endothelial cells': '26.4', 'Cardiomyocytes': '0.437', 'Skeletal myocytes': '-0.131', 'Smooth muscle cells': '27.0', 'Adipocytes': '18.6', 'Melanocytes': '-0.047', 'Fibroblasts': '33.2', 'Peritubular cells': '0.529', 'Endometrial stromal cells': '30.9', 'Ovarian stromal cells': '11.9', 'Undifferentiated cells': '20.2', 'T-cells': '31.4', 'B-cells': '33.4', 'Plasma cells': '101.5', 'Nk-cells': '29.5', 'Granulocytes': '53.1', 'Monocytes': '188.6', 'Macrophages': '54.7', 'Hofbauer cells': '18.2', 'Kupffer cells': '46.0', 'Dendritic cells': '23.2', 'Langerhans cells': '-0.015', 'Erythroid cells': '0.104', 'Adipocytes (Subcutaneous)': '0.365', 'Adipocytes (Visceral)': '-0.058', 'Breast glandular cells (progenitors)': '-0.138', 'Adipocytes (Breast)': '0.261', 'Colon enterocytes': '0.032', 'Colon enteroendocrine cells': '0.134', 'Enteric glia cells': '0.249', 'Mitotic cells (Colon)': '0.178', 'Mitotic cells (Heart)': '0.496', 'Podocytes': '-0.078', 'Ascending Loop of Henle cells': '0.299', 'Intercalated cells': '-0.110', 'Cholangiocyte': '0.302', 'NK-cells (Liver)': '-0.038', 'Respiratory ciliated cells': '-0.020', 'Mitotic cells (Lung)': '0.176', 'NK-cells (Lung)': '-0.194', 'B-cells (Lung)': '-0.052', 'Alpha cells': '0.278', 'Beta cells': '0.202', 'Prostate glandular cells': '0.227', 'Prostate basal glandular cells': '0.480', 'Urothelial cells': '0.329', 'Keratinocyte (other)': '-0.054', 'Keratinocyte (granular)': '-0.122', 'Hair cortex cells': '-0.069', 'Inner root sheath cells': '-0.029', 'Outer root sheath cells': '0.018', 'Sebaceous gland cells': '0.038', 'Eccrine sweat gland cells': '0.022', 'Adipocytes (Skin)': '0.097', 'Mitotic cells (Skin)': '0.045', 'Parietal cells': '-0.195', 'Chief cells': '-0.055', 'Gastric mucous cells': '0.058', 'Gastric enteroendocrine cells': '0.050', 'Mitotic cells (Stomach)': '0.225', 'Parafollicular cells': '-0.075', 'Thyroid glandular cells': '0.343', 'Mitotic cells (Thyroid)': '0.081', 'Adrenal cortex cells': '0.248', 'Adrenal medulla cells': '-0.015', 'Mitotic cells (Adrenal gland)': '0.328', 'Minor salivary glandular cells': '0.487', 'Minor salivary gland ductal cells': '0.176', 'Minor salivary gland basal cells': '0.303', 'Mitotic cells (Minor salivary gland)': '0.374', 'Adipocytes (Minor salivary gland)': '0.261', 'Somatotropes': '-0.191', 'Lactotropes': '-0.218', 'Gonadotropes': '-0.173', 'Corticotropes': '-0.095', 'Thyrotropes': '0.056', 'Undifferentiated cells (Pituitary gland)': '0.250', 'Mitotic cells (Spleen)': '-0.070', 'Platelets': '-0.021', 'Erythrocytes': '-0.061', 'Hematopoietic stem cells': '-0.123', 'B-cells (Spleen)': '0.156', 'NK-cells (Spleen)': '0.197', 'Amygdala excitatory': '49.6', 'Cerebellar inhibitory': '47.8', 'Cge interneuron': '58.8', 'Deep-layer corticothalamic and 6b': '55.4', 'Deep-layer intratelencephalic': '48.6', 'Deep-layer near-projecting': '59.7', 'Eccentric medium spiny neuron': '55.5', 'Hippocampal ca1-3': '49.2', 'Hippocampal ca4': '46.0', 'Hippocampal dentate gyrus': '54.6', 'Lamp5-lhx6 and chandelier': '54.6', 'Lower rhombic lip': '57.5', 'Mammillary body': '56.9', 'Medium spiny neuron': '52.3', 'Mge interneuron': '53.4', 'Midbrain-derived inhibitory': '64.0', 'Miscellaneous': '47.3', 'Splatter': '51.6', 'Thalamic excitatory': '54.3', 'Upper rhombic lip': '57.7', 'Upper-layer intratelencephalic': '43.5', 'Astrocyte': '55.2', 'Bergmann glia': '62.5', 'Central nervous system macrophage': '136.3', 'Choroid plexus epithelial cell': '137.7', 'Committed oligodendrocyte precursor': '65.8', 'Ependymal cell': '72.6', 'Oligodendrocyte': '121.3', 'Oligodendrocyte precursor cell': '58.5', 'Endothelial cell': '62.5', 'Pericyte': '81.1', 'Vascular associated smooth muscle cell': '68.3', 'Fibroblast': '77.9', 'Leukocyte': '77.3', 'Basophil': '45.2', 'Eosinophil': '4.2', 'Neutrophil': '178.2', 'Classical monocyte': '23.4', 'Non-classical monocyte': '29.8', 'Intermediate monocyte': '45.1', 'T-reg': '38.7', 'GdT-cell': '5.2', 'MAIT T-cell': '42.2', 'Memory CD4 T-cell': '4.9', 'Naive CD4 T-cell': '23.5', 'Memory CD8 T-cell': '4.8', 'Naive CD8 T-cell': '21.0', 'Memory B-cell': '4.7', 'Naive B-cell': '26.9', 'Plasmacytoid DC': '30.9', 'Myeloid DC': '25.8', 'NK-cell': '28.0', 'Total PBMC': '34.8', 'Vd2 gdTCR': '34.4', 'Memory CD4 T-cell TFH': '21.8', 'Memory CD4 T-cell Th2': '25.0', 'Memory CD4 T-cell Th17': '21.9', 'Memory CD4 T-cell Th1\\/Th17': '27.1', 'Non-Vd2 gdTCR': '43.4', 'Memory CD4 T-cell Th1': '21.4', 'Terminal effector memory CD4 T-cell': '49.4', 'Central memory CD8 T-cell': '34.2', 'Effector memory CD8 T-cell': '46.9', 'Terminal effector memory CD8 T-cell': '43.5', 'Switched memory B-cell': '37.6', 'Plasmablast': '146.8', 'Non-switched memory B-cell': '31.5', 'Exhausted memory B-cell': '50.4', 'Progenitor cell': '27.5', 'Memory T-reg': '23.4', 'Naive CD4 T-cell activated': '27.0', 'Naive CD8 T-cell activated': '21.4', 'Naive T-reg': '25.0'}
1RV1, 1T4E, 1T4F, 1YCR, 1Z1M, 2AXI, 2C6A, 2C6B, 2F1Y, 2FOP, 2GV2, 2HDP, 2LZG, 2M86, 2MPS, 2RUH, 2VJE, 2VJF, 3EQS, 3G03, 3IUX, 3IWY, 3JZK, 3JZR, 3JZS, 3LBK, 3LBL, 3LNJ, 3LNZ, 3MQS, 3TJ2, 3TPX, 3TU1, 3V3B, 3VBG, 3VZV, 3W69, 4DIJ, 4ERE, 4ERF, 4HBM, 4HFZ, 4HG7, 4JV7, 4JV9, 4JVE, 4JVR, 4JWR, 4MDN, 4MDQ, 4OAS, 4OBA, 4OCC, 4ODE, 4ODF, 4OGN, 4OGT, 4OGV, 4OQ3, 4QO4, 4QOC, 4UD7, 4UE1, 4UMN, 4WT2, 4XXB, 4ZFI, 4ZGK, 4ZYC, 4ZYF, 4ZYI, 5AFG, 5C5A, 5HMH, 5HMI, 5HMK, 5J7F, 5J7G, 5LAV, 5LAW, 5LAY, 5LAZ, 5LN2, 5MNJ, 5OAI, 5OC8, 5SWK, 5TRF, 5UMM, 5VK0, 5WTS, 5XXK, 5Z02, 5ZXF, 6AAW, 6GGN, 6H22, 6HFA, 6I29, 6I3S, 6IM9, 6KZU, 6Q96, 6Q9H, 6Q9L, 6Q9O, 6SQO, 6T2D, 6T2E, 6T2F, 6Y4Q, 6YR6, 7AD0, 7AI0, 7AI1, 7AYE, 7BIR, 7BIT, 7BIV, 7BJ0, 7BJ6, 7BMG, 7KJM, 7NA1, 7NA2, 7NA3, 7NA4, 7NUS, 7QDQ, 8AEU, 8BGU, 8EI9, 8EIA, 8EIB, 8EIC, 8F0Z, 8F10, 8F12, 8F13, 8J81, 8P0D
{'Adipose Tissue': 16.05499003322259, 'Adrenal Gland': 12.543081395348835, 'Bladder': 12.022857142857143, 'Blood': 13.764325296017224, 'Blood Vessel': 11.349043445692883, 'Brain': 6.643090764572293, 'Breast': 15.301727668845317, 'Cervix Uteri': 14.300210526315787, 'Colon': 7.945577663671373, 'Esophagus': 9.642425605536332, 'Fallopian Tube': 13.622777777777776, 'Heart': 3.9124594657375145, 'Kidney': 6.41938202247191, 'Liver': 9.845287610619469, 'Lung': 19.009126297577858, 'Muscle': 9.91624408468244, 'Nerve': 16.381084006462036, 'Ovary': 13.726133333333337, 'Pancreas': 7.2400518292682925, 'Pituitary': 8.908618374558305, 'Prostate': 14.564322448979592, 'Salivary Gland': 10.47354938271605, 'Skin': 20.616034273079052, 'Small Intestine': 9.19466310160428, 'Spleen': 14.59016182572614, 'Stomach': 8.134596100278552, 'Testis': 7.357628808864265, 'Thyroid': 13.1375865237366, 'Uterus': 12.31338028169014, 'Vagina': 14.372166666666669}
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RING finger
null
null
null
VCP,AKT1,MDM2,SQSTM1, TRAF6,IKBKG
MDM2, AKT1, TRAF6, IKBKG
29
null
null
null
null
79.775479
0.523071
62.294318
0.706701
1,616
O60907
P35222
20181957, E3Net
UbiNet, UbiBrowser, 31181401
TBL1X
MTELAGASSSCCHRPAGRGAMQSVLHHFQRLRGREGGSHFINTSSPRGEAKMSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAAATAAATAATTTSAGVSHQNPSKNREATVNGEENRAHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK
Homo sapiens
Nucleus
Low tissue specificity
{'Ciliated cells': '20.3', 'Basal respiratory cells': '4.2', 'Club cells': '19.6', 'Ionocytes': '5.5', 'Mucus glandular cells': '22.3', 'Serous glandular cells': '19.9', 'Gastric mucus-secreting cells': '10.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '9.7', 'Distal enterocytes': '5.9', 'Intestinal goblet cells': '4.4', 'Exocrine glandular cells': '-0.597', 'Basal prostatic cells': '15.9', 'Prostatic glandular cells': '19.4', 'Breast glandular cells': '0.458', 'Breast myoepithelial cells': '0.421', 'Glandular and luminal cells': '50.1', 'Secretory cells': '12.5', 'Basal keratinocytes': '15.6', 'Suprabasal keratinocytes': '24.2', 'Basal squamous epithelial cells': '8.0', 'Squamous epithelial cells': '18.5', 'Alveolar cells type 1': '0.050', 'Alveolar cells type 2': '-0.466', 'Salivary duct cells': '20.2', 'Ductal cells': '0.606', 'Hepatocytes': '0.546', 'Cholangiocytes': '17.2', 'Proximal tubular cells': '0.070', 'Distal tubular cells': '6.1', 'Collecting duct cells': '29.2', 'Mesothelial cells': '0.040', 'Sertoli cells': '0.775', 'Granulosa cells': '9.2', 'Enteroendocrine cells': '18.3', 'Pancreatic endocrine cells': '13.6', 'Leydig cells': '0.622', 'Excitatory neurons': '12.0', 'Inhibitory neurons': '16.3', 'Cone photoreceptor cells': '22.1', 'Rod photoreceptor cells': '27.0', 'Bipolar cells': '11.5', 'Horizontal cells': '24.5', 'Astrocytes': '98.5', 'Oligodendrocyte precursor cells': '43.4', 'Oligodendrocytes': '102.1', 'Microglial cells': '59.0', 'Muller glia cells': '41.8', 'Schwann cells': '0.035', 'Spermatogonia': '0.587', 'Spermatocytes': '0.125', 'Early spermatids': '-0.577', 'Late spermatids': '-0.736', 'Oocytes': '5.9', 'Cytotrophoblasts': '77.3', 'Syncytiotrophoblasts': '41.7', 'Extravillous trophoblasts': '2.0', 'Endothelial cells': '12.3', 'Lymphatic endothelial cells': '9.4', 'Cardiomyocytes': '0.523', 'Skeletal myocytes': '-0.293', 'Smooth muscle cells': '31.1', 'Adipocytes': '12.7', 'Melanocytes': '-0.022', 'Fibroblasts': '14.5', 'Peritubular cells': '0.564', 'Endometrial stromal cells': '78.0', 'Ovarian stromal cells': '13.2', 'Undifferentiated cells': '6.0', 'T-cells': '18.0', 'B-cells': '16.7', 'Plasma cells': '8.2', 'Nk-cells': '27.4', 'Granulocytes': '13.7', 'Monocytes': '31.0', 'Macrophages': '22.8', 'Hofbauer cells': '9.8', 'Kupffer cells': '31.2', 'Dendritic cells': '10.7', 'Langerhans cells': '0.086', 'Erythroid cells': '-0.149', 'Adipocytes (Subcutaneous)': '0.041', 'Adipocytes (Visceral)': '0.032', 'Breast glandular cells (progenitors)': '0.413', 'Adipocytes (Breast)': '-0.339', 'Colon enterocytes': '-0.271', 'Colon enteroendocrine cells': '0.161', 'Enteric glia cells': '0.009', 'Mitotic cells (Colon)': '-0.115', 'Mitotic cells (Heart)': '0.450', 'Podocytes': '-0.019', 'Ascending Loop of Henle cells': '0.587', 'Intercalated cells': '0.110', 'Cholangiocyte': '0.069', 'NK-cells (Liver)': '-0.150', 'Respiratory ciliated cells': '0.119', 'Mitotic cells (Lung)': '-0.148', 'NK-cells (Lung)': '0.409', 'B-cells (Lung)': '0.270', 'Alpha cells': '0.436', 'Beta cells': '0.203', 'Prostate glandular cells': '-0.445', 'Prostate basal glandular cells': '-0.186', 'Urothelial cells': '-0.074', 'Keratinocyte (other)': '0.080', 'Keratinocyte (granular)': '0.049', 'Hair cortex cells': '-0.010', 'Inner root sheath cells': '0.054', 'Outer root sheath cells': '0.134', 'Sebaceous gland cells': '-0.005', 'Eccrine sweat gland cells': '0.127', 'Adipocytes (Skin)': '0.076', 'Mitotic cells (Skin)': '0.084', 'Parietal cells': '-0.691', 'Chief cells': '-0.495', 'Gastric mucous cells': '-0.565', 'Gastric enteroendocrine cells': '-0.439', 'Mitotic cells (Stomach)': '-0.186', 'Parafollicular cells': '0.141', 'Thyroid glandular cells': '0.546', 'Mitotic cells (Thyroid)': '-0.050', 'Adrenal cortex cells': '0.269', 'Adrenal medulla cells': '-0.008', 'Mitotic cells (Adrenal gland)': '0.180', 'Minor salivary glandular cells': '0.586', 'Minor salivary gland ductal cells': '0.004', 'Minor salivary gland basal cells': '0.300', 'Mitotic cells (Minor salivary gland)': '0.341', 'Adipocytes (Minor salivary gland)': '0.078', 'Somatotropes': '0.294', 'Lactotropes': '0.140', 'Gonadotropes': '0.371', 'Corticotropes': '-0.077', 'Thyrotropes': '0.363', 'Undifferentiated cells (Pituitary gland)': '0.015', 'Mitotic cells (Spleen)': '-0.252', 'Platelets': '-0.050', 'Erythrocytes': '-0.092', 'Hematopoietic stem cells': '-0.117', 'B-cells (Spleen)': '0.337', 'NK-cells (Spleen)': '0.343', 'Amygdala excitatory': '45.7', 'Cerebellar inhibitory': '7.8', 'Cge interneuron': '38.4', 'Deep-layer corticothalamic and 6b': '42.0', 'Deep-layer intratelencephalic': '28.7', 'Deep-layer near-projecting': '35.8', 'Eccentric medium spiny neuron': '68.1', 'Hippocampal ca1-3': '38.0', 'Hippocampal ca4': '13.5', 'Hippocampal dentate gyrus': '38.0', 'Lamp5-lhx6 and chandelier': '1.5', 'Lower rhombic lip': '37.7', 'Mammillary body': '24.6', 'Medium spiny neuron': '172.9', 'Mge interneuron': '19.2', 'Midbrain-derived inhibitory': '2.6', 'Miscellaneous': '51.6', 'Splatter': '48.7', 'Thalamic excitatory': '30.5', 'Upper rhombic lip': '31.2', 'Upper-layer intratelencephalic': '11.6', 'Astrocyte': '230.7', 'Bergmann glia': '97.1', 'Central nervous system macrophage': '113.3', 'Choroid plexus epithelial cell': '112.7', 'Committed oligodendrocyte precursor': '110.7', 'Ependymal cell': '269.9', 'Oligodendrocyte': '225.9', 'Oligodendrocyte precursor cell': '98.9', 'Endothelial cell': '215.5', 'Pericyte': '207.8', 'Vascular associated smooth muscle cell': '356.9', 'Fibroblast': '134.3', 'Leukocyte': '260.3', 'Basophil': '38.6', 'Eosinophil': '5.8', 'Neutrophil': '132.5', 'Classical monocyte': '43.7', 'Non-classical monocyte': '24.9', 'Intermediate monocyte': '21.0', 'T-reg': '13.3', 'GdT-cell': '2.2', 'MAIT T-cell': '9.4', 'Memory CD4 T-cell': '1.7', 'Naive CD4 T-cell': '28.8', 'Memory CD8 T-cell': '2.0', 'Naive CD8 T-cell': '26.1', 'Memory B-cell': '2.2', 'Naive B-cell': '31.4', 'Plasmacytoid DC': '1.6', 'Myeloid DC': '28.6', 'NK-cell': '28.2', 'Total PBMC': '19.1', 'Vd2 gdTCR': '15.8', 'Memory CD4 T-cell Th1\\/Th17': '18.6', 'Memory CD4 T-cell Th17': '18.3', 'Memory CD4 T-cell Th2': '22.2', 'Non-Vd2 gdTCR': '15.5', 'Memory CD4 T-cell Th1': '22.7', 'Memory CD4 T-cell TFH': '24.2', 'Terminal effector memory CD4 T-cell': '17.3', 'Central memory CD8 T-cell': '15.4', 'Effector memory CD8 T-cell': '17.1', 'Terminal effector memory CD8 T-cell': '14.8', 'Non-switched memory B-cell': '13.6', 'Plasmablast': '3.4', 'Switched memory B-cell': '13.1', 'Exhausted memory B-cell': '20.4', 'Progenitor cell': '6.5', 'Memory T-reg': '19.0', 'Naive CD4 T-cell activated': '87.5', 'Naive CD8 T-cell activated': '106.2', 'Naive T-reg': '24.7'}
2XTC, 2XTD, 2XTE
{'Adipose Tissue': 11.53654485049834, 'Adrenal Gland': 11.814767441860464, 'Bladder': 30.953238095238095, 'Blood': 19.272019698600648, 'Blood Vessel': 34.63300973782771, 'Brain': 9.665269871309611, 'Breast': 11.818636165577342, 'Cervix Uteri': 45.20789473684211, 'Colon': 14.815804878048782, 'Esophagus': 18.855087889273356, 'Fallopian Tube': 28.833333333333332, 'Heart': 3.829, 'Kidney': 12.799752808988766, 'Liver': 9.722699115044248, 'Lung': 12.003929065743945, 'Muscle': 4.846562889165629, 'Nerve': 16.39106462035541, 'Ovary': 26.041722222222223, 'Pancreas': 3.879432926829268, 'Pituitary': 37.72719434628976, 'Prostate': 34.77043265306122, 'Salivary Gland': 10.082092592592591, 'Skin': 13.717822001105583, 'Small Intestine': 9.180566844919786, 'Spleen': 10.54241908713693, 'Stomach': 11.789231197771588, 'Testis': 18.673950138504157, 'Thyroid': 20.51241960183767, 'Uterus': 84.16922535211268, 'Vagina': 27.287628205128204}
CTNNB1
MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL
Homo sapiens
Cytoplasm, Nucleus, Cytoplasm, cytoskeleton, Cell junction, adherens junction, Cell junction, Cell membrane, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cytoskeleton, spindle pole, Synapse, Cytoplasm, cytoskeleton, cilium basal body
Low tissue specificity
{'Ciliated cells': '95.8', 'Basal respiratory cells': '72.3', 'Club cells': '99.0', 'Ionocytes': '73.3', 'Mucus glandular cells': '137.3', 'Serous glandular cells': '72.3', 'Gastric mucus-secreting cells': '45.4', 'Proximal enterocytes': '141.4', 'Paneth cells': '171.7', 'Distal enterocytes': '152.4', 'Intestinal goblet cells': '125.3', 'Exocrine glandular cells': '-0.695', 'Basal prostatic cells': '123.7', 'Prostatic glandular cells': '78.5', 'Breast glandular cells': '0.555', 'Breast myoepithelial cells': '0.593', 'Glandular and luminal cells': '85.3', 'Secretory cells': '126.7', 'Basal keratinocytes': '165.8', 'Suprabasal keratinocytes': '138.2', 'Basal squamous epithelial cells': '91.1', 'Squamous epithelial cells': '69.2', 'Alveolar cells type 1': '0.281', 'Alveolar cells type 2': '0.054', 'Salivary duct cells': '140.9', 'Ductal cells': '0.758', 'Hepatocytes': '0.536', 'Cholangiocytes': '66.8', 'Proximal tubular cells': '0.239', 'Distal tubular cells': '40.0', 'Collecting duct cells': '60.3', 'Mesothelial cells': '0.098', 'Sertoli cells': '0.604', 'Granulosa cells': '65.7', 'Enteroendocrine cells': '97.4', 'Pancreatic endocrine cells': '244.5', 'Leydig cells': '0.693', 'Excitatory neurons': '49.2', 'Inhibitory neurons': '78.8', 'Cone photoreceptor cells': '44.2', 'Rod photoreceptor cells': '54.3', 'Bipolar cells': '42.7', 'Horizontal cells': '30.8', 'Astrocytes': '55.1', 'Oligodendrocyte precursor cells': '66.5', 'Oligodendrocytes': '58.5', 'Microglial cells': '119.0', 'Muller glia cells': '88.0', 'Schwann cells': '0.103', 'Spermatogonia': '0.611', 'Spermatocytes': '0.368', 'Early spermatids': '-0.498', 'Late spermatids': '-0.721', 'Oocytes': '50.7', 'Cytotrophoblasts': '294.5', 'Syncytiotrophoblasts': '463.4', 'Extravillous trophoblasts': '106.1', 'Endothelial cells': '151.2', 'Lymphatic endothelial cells': '159.1', 'Cardiomyocytes': '0.532', 'Skeletal myocytes': '-0.210', 'Smooth muscle cells': '117.6', 'Adipocytes': '159.1', 'Melanocytes': '0.101', 'Fibroblasts': '113.9', 'Peritubular cells': '0.572', 'Endometrial stromal cells': '106.7', 'Ovarian stromal cells': '70.6', 'Undifferentiated cells': '122.4', 'T-cells': '73.2', 'B-cells': '72.7', 'Plasma cells': '43.6', 'Nk-cells': '105.7', 'Granulocytes': '129.5', 'Monocytes': '570.0', 'Macrophages': '183.5', 'Hofbauer cells': '136.4', 'Kupffer cells': '172.2', 'Dendritic cells': '62.7', 'Langerhans cells': '-0.020', 'Erythroid cells': '-0.065', 'Adipocytes (Subcutaneous)': '-0.228', 'Adipocytes (Visceral)': '-0.099', 'Breast glandular cells (progenitors)': '0.610', 'Adipocytes (Breast)': '-0.426', 'Colon enterocytes': '0.029', 'Colon enteroendocrine cells': '0.275', 'Enteric glia cells': '-0.189', 'Mitotic cells (Colon)': '0.159', 'Mitotic cells (Heart)': '0.532', 'Podocytes': '-0.084', 'Ascending Loop of Henle cells': '0.424', 'Intercalated cells': '-0.070', 'Cholangiocyte': '0.356', 'NK-cells (Liver)': '-0.289', 'Respiratory ciliated cells': '0.108', 'Mitotic cells (Lung)': '-0.041', 'NK-cells (Lung)': '0.217', 'B-cells (Lung)': '0.011', 'Alpha cells': '0.428', 'Beta cells': '0.238', 'Prostate glandular cells': '-0.311', 'Prostate basal glandular cells': '0.151', 'Urothelial cells': '0.119', 'Keratinocyte (other)': '-0.289', 'Keratinocyte (granular)': '-0.413', 'Hair cortex cells': '0.541', 'Inner root sheath cells': '0.608', 'Outer root sheath cells': '0.665', 'Sebaceous gland cells': '0.148', 'Eccrine sweat gland cells': '0.453', 'Adipocytes (Skin)': '0.316', 'Mitotic cells (Skin)': '0.363', 'Parietal cells': '-0.667', 'Chief cells': '-0.618', 'Gastric mucous cells': '-0.312', 'Gastric enteroendocrine cells': '-0.437', 'Mitotic cells (Stomach)': '0.145', 'Parafollicular cells': '0.032', 'Thyroid glandular cells': '0.223', 'Mitotic cells (Thyroid)': '0.173', 'Adrenal cortex cells': '0.528', 'Adrenal medulla cells': '0.066', 'Mitotic cells (Adrenal gland)': '0.320', 'Minor salivary glandular cells': '0.712', 'Minor salivary gland ductal cells': '0.323', 'Minor salivary gland basal cells': '0.285', 'Mitotic cells (Minor salivary gland)': '0.331', 'Adipocytes (Minor salivary gland)': '0.217', 'Somatotropes': '-0.227', 'Lactotropes': '-0.313', 'Gonadotropes': '-0.048', 'Corticotropes': '-0.325', 'Thyrotropes': '-0.118', 'Undifferentiated cells (Pituitary gland)': '0.610', 'Mitotic cells (Spleen)': '-0.262', 'Platelets': '-0.076', 'Erythrocytes': '-0.115', 'Hematopoietic stem cells': '-0.180', 'B-cells (Spleen)': '0.245', 'NK-cells (Spleen)': '0.257', 'Amygdala excitatory': '114.9', 'Cerebellar inhibitory': '118.5', 'Cge interneuron': '153.9', 'Deep-layer corticothalamic and 6b': '107.9', 'Deep-layer intratelencephalic': '81.1', 'Deep-layer near-projecting': '84.3', 'Eccentric medium spiny neuron': '120.7', 'Hippocampal ca1-3': '108.2', 'Hippocampal ca4': '129.4', 'Hippocampal dentate gyrus': '122.2', 'Lamp5-lhx6 and chandelier': '130.1', 'Lower rhombic lip': '51.7', 'Mammillary body': '114.4', 'Medium spiny neuron': '115.8', 'Mge interneuron': '111.9', 'Midbrain-derived inhibitory': '171.1', 'Miscellaneous': '100.5', 'Splatter': '110.5', 'Thalamic excitatory': '200.2', 'Upper rhombic lip': '263.8', 'Upper-layer intratelencephalic': '110.2', 'Astrocyte': '112.9', 'Bergmann glia': '301.0', 'Central nervous system macrophage': '245.4', 'Choroid plexus epithelial cell': '171.9', 'Committed oligodendrocyte precursor': '98.0', 'Ependymal cell': '258.0', 'Oligodendrocyte': '109.5', 'Oligodendrocyte precursor cell': '131.8', 'Endothelial cell': '823.7', 'Pericyte': '161.1', 'Vascular associated smooth muscle cell': '280.9', 'Fibroblast': '203.0', 'Leukocyte': '242.8', 'Basophil': '143.7', 'Eosinophil': '6.4', 'Neutrophil': '102.0', 'Classical monocyte': '383.4', 'Non-classical monocyte': '264.9', 'Intermediate monocyte': '132.0', 'T-reg': '72.3', 'GdT-cell': '9.2', 'MAIT T-cell': '71.7', 'Memory CD4 T-cell': '8.7', 'Naive CD4 T-cell': '152.7', 'Memory CD8 T-cell': '10.1', 'Naive CD8 T-cell': '134.9', 'Memory B-cell': '7.7', 'Naive B-cell': '177.0', 'Plasmacytoid DC': '73.4', 'Myeloid DC': '113.6', 'NK-cell': '182.4', 'Total PBMC': '104.6', 'Vd2 gdTCR': '90.0', 'Memory CD4 T-cell Th1\\/Th17': '143.2', 'Memory CD4 T-cell Th17': '138.9', 'Memory CD4 T-cell Th2': '139.5', 'Non-Vd2 gdTCR': '90.2', 'Memory CD4 T-cell Th1': '139.7', 'Memory CD4 T-cell TFH': '145.7', 'Terminal effector memory CD4 T-cell': '84.8', 'Central memory CD8 T-cell': '75.0', 'Effector memory CD8 T-cell': '86.8', 'Terminal effector memory CD8 T-cell': '84.4', 'Non-switched memory B-cell': '67.1', 'Plasmablast': '67.0', 'Switched memory B-cell': '78.5', 'Exhausted memory B-cell': '81.3', 'Progenitor cell': '114.1', 'Memory T-reg': '148.3', 'Naive CD4 T-cell activated': '142.0', 'Naive CD8 T-cell activated': '127.7', 'Naive T-reg': '164.2'}
1G3J, 1JDH, 1JPW, 1LUJ, 1P22, 1QZ7, 1T08, 1TH1, 2G57, 2GL7, 2Z6H, 3DIW, 3FQN, 3FQR, 3SL9, 3SLA, 3TX7, 4DJS, 6M90, 6M91, 6M92, 6M93, 6M94, 6O9B, 6O9C, 6WLX, 6WNX, 7AFW, 7AR4, 7UWI, 7UWO, 7ZRB, 8EI9, 8EIA, 8EIB, 8EIC, 8Y0G, 8Y0P, 8Y14, 8Z0U, 8Z10, 8Z5J, 8Z61
{'Adipose Tissue': 125.40916943521596, 'Adrenal Gland': 109.41143410852712, 'Bladder': 128.8733333333333, 'Blood': 37.61978471474704, 'Blood Vessel': 195.71696629213483, 'Brain': 75.98141786525359, 'Breast': 138.5178431372549, 'Cervix Uteri': 263.7473684210526, 'Colon': 113.96857509627728, 'Esophagus': 102.9303875432526, 'Fallopian Tube': 165.25555555555556, 'Heart': 48.762599303135886, 'Kidney': 52.192247191011234, 'Liver': 37.37945575221239, 'Lung': 166.2987024221453, 'Muscle': 37.76417185554172, 'Nerve': 186.45481421647816, 'Ovary': 202.9044444444445, 'Pancreas': 38.000277439024394, 'Pituitary': 120.81908127208482, 'Prostate': 142.71008163265307, 'Salivary Gland': 123.25006172839504, 'Skin': 130.7604754007739, 'Small Intestine': 126.9548128342246, 'Spleen': 101.15473029045644, 'Stomach': 76.7383286908078, 'Testis': 64.05828254847646, 'Thyroid': 167.25387442572742, 'Uterus': 196.5591549295775, 'Vagina': 155.94717948717948}
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33.28, 31.4, 32.87, 33.52, 32.84, 33.99, 29.16, 30.17, 31.48, 36.08, 32.02, 28.77, 26.96, 29.05, 32.98, 32.21, 31.03, 31.94, 34.61, 32.18, 39.06, 28.57, 32.87, 31.81, 31.69, 32.39, 29.91, 27.64, 27.09, 26.45, 31.74, 26.99, 27.32, 25.66, 28.3, 26.79, 29.12, 29.8, 33.18, 35.05, 29.0, 28.21, 26.53, 26.25, 28.8, 26.69, 27.88, 27.57, 31.08, 28.65, 26.92, 28.44, 38.31, 29.68, 31.55, 32.53, 32.12, 29.0]
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null
F-box-like protein, Component of a E3 ubiquitin ligase complex containing UBE2D1, SIAH1, CACYBP/SIP, SKP1, APC and TBL1X
null
null
GSP2, H2B, H3a , H4, MECP2, USP44, UBE2D1, SIAH1, CACYBP, SKP1, APC , TBL1X
null
null
null
UBE2D1
Homotetramer
null
82.286308
0.391889
80.826056
0.413534
834
O64425
P43286
22199232
UbiNet, UbiBrowser
RMA1
MALDQSFEDAALLGELYGEGAFCFKSKKPEPITVSVPSDDTDDSNFDCNICLDSVQEPVVTLCGHLFCWPCIHKWLDVQSFSTSDEYQRHRQCPVCKSKVSHSTLVPLYGRGRCTTQEEGKNSVPKRPVGPVYRLEMPNSPYASTDLRLSQRVHFNSPQEGYYPVSGVMSSNSLSYSAVLDPVMVMVGEMVATRLFGTRVMDRFAYPDTYNLAGTSGPRMRRRIMQADKSLGRIFFFFMCCVVLCLLLF
Arabidopsis thaliana
Endoplasmic reticulum membrane
Not found
{}
null
{}
PIP2-1
MAKDVEAVPGEGFQTRDYQDPPPAPFIDGAELKKWSFYRAVIAEFVATLLFLYITVLTVIGYKIQSDTDAGGVDCGGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLFLARKVSLPRALLYIIAQCLGAICGVGFVKAFQSSYYTRYGGGANSLADGYSTGTGLAAEIIGTFVLVYTVFSATDPKRSARDSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNKSKPWDDHWIFWVGPFIGAAIAAFYHQFVLRASGSKSLGSFRSAANV
Arabidopsis thaliana
Cell membrane
Not found
{}
null
{}
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null
null
null
null
null
null
null
null
null
null
null
62.166225
0.670201
89.53885
0.328711
2,438
O65020
Q37001
22199232
UbiNet, UbiBrowser
ETO1
MRSLKLAEGCKGTQVYALNPSAPTPPPPPGNSSTGGGGGGGSGGGTGGVGDKLLQHLSDHLRVNSVRSKSSRTYPPPTQPNAVVSPEFLLPCGLPVTDLLEPQIDPCLKFVDLVEKMAQVYRRIENCSQFEKSGAYLEQCAIFRGISDPKLFRRSLRSSRQHAVDVHAKVVLASWLRFERREDELIGTTSMDCCGRNLECPKATLVSGYDPESVYDPCVCSGASRSEMMNEDECSTSQEVDYDMSFCIGDEEVRCVRYKIASLSRPFKAMLYGGFREMKRATINFTQNGISVEGMRAAEIFSRTNRLDNFPPNVVLELLKLANRFCCDELKSACDSHLAHLVNSLDEAMLLIEYGLEEAAYLLVAACLQVFLRELPSSMHNPNVIKIFCSAEGRERLASLGHASFTLYFFLSQIAMEDDMKSNTTVMLLERLVECAVDSWEKQLAYHQLGVVMLERKEYKDAQRWFNAAVEAGHLYSLVGVARTKFKRDHRYSAYKIINSLISDHKATGWMHQERSLYCSGKEKLLDLDTATEFDPTLTFPYKFRAVALVEENQFGAAIAELNKILGFKASPDCLEMRAWISIGMEDYEGALKDIRALLTLEPNFMMFNWKIHGDHMVELLRPLAQQWSQADCWMQLYDRWSSVDDIGSLAVVHHMLANDPGKSLLRFRQSLLLLRLNCQKAAMRSLRLARNHSKSEHERLVYEGWILYDTGHREEALAKAEESISIQRSFEAFFLKAYALADSTLDPDSSNYVIQLLQEALKCPSDGLRKGQALNNLGSVYVDCEKLDLAADCYTNALTIKHTRAHQGLARVYHLKNQRKAAYDEMTKLIEKAQNNASAYEKRSEYCDREMAQSDLCLATQLDPLRTYPYRYRAAVLMDDHKESEAIDELSRAISFKPDLQLLHLRAAFYDSMGEGASAIKDCEAALCIDPGHADTLELYHKAREPNDQK
Arabidopsis thaliana
null
Not found
{}
null
{}
ACS5
MKQLSTKVTSNGHGQDSSYFLGWEEYEKNPYDEIKNPNGMIQMGLAENQLCFDLIESWLTKNPDAASLKRNGQSIFRELALFQDYHGMPEFKKAMAEFMEEIRGNRVTFDPKKIVLAAGSTSANETLMFCLAEPGDAFLLPTPYYPGFDRDLKWRTGAEIVPIHCSSSNGFQITESALQQAYQQAQKLDLKVKGVLVTNPSNPLGTALTRRELNLLVDFITSKNIHLISDEIYSGTMFGFEQFISVMDVLKDKKLEDTEVSKRVHVVYSLSKDLGLPGFRVGAIYSNDEMIVSAATKMSSFGLVSSQTQYLLSALLSDKKFTSQYLEENQKRLKSRQRRLVSGLESAGITCLRSNAGLFCWVDMRHLLDTNTFEAELDLWKKIVYNVKLNISPGSSCHCTEPGWFRVCFANMSEDTLDLALKRLKTFVESTDCGRMISRSSHERLKSLRKKTVSNWVFRVSWTDRVPDER
Arabidopsis thaliana
null
Not found
{}
null
{}
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null
null
null
null
null
null
null
null
null
null
null
86.384869
0.326351
92.519383
0.307511
1,677
O70263
O54851
30295974
UbiBrowser
Lnx1
MNQPDLADDPDPSPEPLCIVCGQNHSPEENHFYTYTEDVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSSILVNKLLNKLLVTCPFTEHCTEVLQRCDLQHHFQTSCKGASHYGLTKDRKRRSQDGCPDGCASLMATTLSPEVSAAATISLMTDEPGLDNPAYVSSVEDGEPVANSSDSGRSNRTRARPFERSTMRSRSFKKINRALSALRRTKSGSVVANHVDQGRDNSENTTVPEVFPRLFHLIPDGEITSIKINRADPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLRLTVLREQKFRSRSNAHVPDSYGPRDDSFHVILNKSSPEEQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSPESAAHLIQASERRVHLVVSRQVRQSSPDIFQEAGWISNGQQSPGPGERNTASKPAATCHEKVVSVWKDPSESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVAILKSAPSSVVLKALEVKEQEAQEDCSPAALDSNHNVTPPGDWSPSWVMWLELPQYLCNCKDVILRRNTAGSLGFCIVGGYEEYSGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARMLKELKGRITLTIASWPGTFL
Mus musculus
Cytoplasm
Not found
{}
3VQF, 3VQG
{}
Gjd2
MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRERRYSTVFLALDRDPAESIGGPGGTGGGGSGGSKREDKKLQNAIVNGVLQNTETTSKETEPDCLEVKELTPHPSGLRTAARSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRKSVYEIRNKDLPRVSVPNFGRTQSSDSAYV
Mus musculus
Cell membrane, Cell junction, gap junction
Not found
{}
null
{}
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[55.36, 73.5, 76.72, 74.61, 80.3, 75.72, 72.4, 78.08, 70.21, 63.62, 64.09, 65.01, 55.18, 52.45, 53.44, 45.09, 47.86, 41.91, 45.66, 60.77, 64.54, 67.29, 68.45, 71.7, 77.07, 78.71, 75.94, 82.12, 85.43, 85.45, 86.94, 89.79, 90.7, 91.14, 92.24, 93.83, 92.87, 93.52, 93.46, 93.15, 91.32, 89.26, 88.82, 92.82, 93.32, 93.78, 92.8, 93.2, 92.45, 91.29, 92.98, 93.96, 95.58, 95.9, 96.65, 95.0, 94.46, 93.52, 93.68, 95.2, 94.72, 96.05, 94.92, 94.63, 95.77, 96.76, 95.54, 95.4, 94.81, 93.73, 94.03, 93.69, 94.46, 93.54, 93.08, 93.07, 94.09, 95.52, 94.91, 94.82, 95.17, 95.06, 93.11, 94.07, 94.98, 91.76, 90.33, 91.99, 88.77, 85.76, 86.83, 89.23, 84.16, 81.77, 84.83, 83.57, 79.93, 80.16, 86.24, 80.46, 76.13, 83.83, 84.4, 76.02, 77.7, 80.72, 77.97, 74.22, 70.41, 76.45, 77.75, 74.5, 75.95, 75.79, 71.25, 67.32, 70.32, 60.76, 51.39, 52.47, 45.16, 44.39, 41.12, 47.73, 38.9, 36.8, 44.84, 42.65, 40.91, 43.67, 39.22, 38.45, 35.05, 33.21, 38.35, 33.87, 36.99, 45.44, 42.45, 38.91, 48.28, 53.42, 53.76, 55.16, 59.74, 59.02, 58.95, 63.24, 61.31, 60.64, 56.91, 59.45, 56.81, 52.58, 47.53, 45.92, 46.59, 39.44, 30.75, 32.82, 31.08, 33.91, 31.95, 31.46, 29.0, 34.24, 28.67, 30.64, 37.1, 29.52, 36.41, 30.54, 31.95, 36.48, 31.04, 40.81, 36.02, 44.65, 44.85, 44.6, 47.6, 49.02, 54.79, 56.61, 56.6, 57.53, 54.87, 58.53, 59.73, 58.75, 59.16, 62.26, 62.18, 64.3, 68.2, 70.75, 78.77, 80.54, 78.18, 81.24, 85.29, 85.95, 85.14, 88.44, 91.6, 90.11, 90.59, 94.1, 95.51, 94.06, 95.93, 96.85, 96.81, 96.24, 96.9, 96.07, 96.23, 95.89, 95.9, 93.83, 93.36, 93.56, 93.54, 94.81, 94.05, 94.21, 94.27, 95.86, 95.41, 96.43, 96.91, 95.72, 94.68, 94.38, 95.53, 94.99, 92.21, 92.03, 95.57, 96.22, 96.78, 97.12, 96.74, 95.7, 94.9, 94.55, 95.8, 95.86, 94.62, 95.06, 95.97, 95.04, 93.77, 94.44, 95.45, 93.82, 93.12, 95.04, 94.21, 91.84, 92.29, 93.5, 90.18, 88.3, 91.28, 90.05, 86.44, 83.63, 86.5, 85.3, 81.14, 80.64, 82.74, 78.93, 74.81, 74.71, 73.59, 76.31, 72.52, 73.28, 78.18, 77.59, 74.34, 76.66, 81.28, 77.03, 75.01, 77.89, 77.53, 76.45, 74.49, 75.55, 76.41, 74.68, 68.93, 73.08, 72.08, 68.29, 69.47, 63.48, 56.16, 52.87, 49.58, 47.68, 45.31, 43.83, 49.71, 43.95, 41.36, 44.19, 38.74, 39.03, 43.98, 42.07, 41.83, 42.84, 44.34, 47.35, 52.24, 39.14, 45.31]
[0.87, 0.49, 0.84, 0.77, 0.51, 0.62, 0.61, 0.56, 0.74, 0.59, 0.61, 0.54, 0.52, 0.28, 0.55, 0.89, 0.78, 0.2, 0.42, 0.33, 0.45, 0.45, 0.21, 0.41, 0.52, 0.45, 0.21, 0.53, 0.56, 0.2, 0.22, 0.49, 0.43, 0.07, 0.45, 0.53, 0.14, 0.1, 0.5, 0.65, 0.26, 0.12, 0.75, 0.56, 0.01, 0.04, 0.75, 0.15, 0.12, 0.62, 0.76, 0.58, 0.03, 0.54, 0.09, 0.67, 0.33, 0.96, 0.35, 0.83, 0.44, 0.0, 0.34, 0.77, 0.16, 0.0, 0.1, 0.49, 0.64, 0.26, 0.18, 0.65, 0.52, 0.01, 0.03, 0.18, 0.58, 0.08, 0.03, 0.42, 0.51, 0.05, 0.18, 0.56, 0.34, 0.07, 0.22, 0.44, 0.11, 0.2, 0.6, 0.48, 0.16, 0.55, 0.63, 0.45, 0.32, 0.62, 0.62, 0.28, 0.5, 0.46, 0.41, 0.17, 0.63, 0.69, 0.6, 0.67, 0.62, 0.49, 0.65, 0.34, 0.65, 0.61, 0.64, 0.27, 0.74, 0.84, 0.82, 0.89, 0.91, 0.91, 0.99, 0.94, 0.98, 1.0, 1.0, 0.98, 0.95, 1.0, 0.98, 1.0, 0.98, 1.0, 0.98, 1.0, 0.81, 0.64, 0.84, 0.81, 0.7, 0.62, 0.67, 0.69, 0.61, 0.38, 0.59, 0.53, 0.42, 0.35, 0.59, 0.37, 0.44, 0.51, 0.71, 0.81, 0.54, 0.87, 0.87, 0.96, 0.96, 1.0, 1.0, 0.96, 0.98, 0.96, 0.86, 0.98, 0.82, 0.89, 0.89, 0.9, 0.94, 0.92, 0.99, 0.7, 0.79, 0.71, 0.65, 0.49, 0.58, 0.72, 0.59, 0.41, 0.51, 0.7, 0.54, 0.7, 0.56, 0.78, 0.34, 0.69, 0.43, 0.41, 0.41, 0.43, 0.65, 0.33, 0.19, 0.53, 0.6, 0.1, 0.12, 0.47, 0.51, 0.07, 0.1, 0.52, 0.16, 0.07, 0.39, 0.53, 0.11, 0.18, 0.48, 0.25, 0.02, 0.56, 0.8, 0.66, 0.15, 0.29, 0.45, 0.67, 0.09, 0.51, 0.36, 0.42, 0.25, 0.63, 0.04, 0.79, 0.38, 0.92, 0.27, 0.19, 0.81, 0.82, 0.69, 0.1, 0.42, 0.0, 0.5, 0.11, 0.12, 0.43, 0.24, 0.76, 0.4, 0.05, 0.19, 0.65, 0.07, 0.0, 0.46, 0.43, 0.03, 0.23, 0.47, 0.14, 0.03, 0.22, 0.57, 0.09, 0.09, 0.62, 0.51, 0.13, 0.35, 0.51, 0.18, 0.35, 0.48, 0.6, 0.29, 0.27, 0.71, 0.66, 0.73, 0.56, 0.58, 0.63, 0.56, 0.49, 0.63, 0.48, 0.46, 0.56, 0.51, 0.69, 0.78, 0.72, 0.41, 0.58, 0.72, 0.59, 0.59, 0.77, 0.61, 0.74, 0.68, 0.71, 0.79, 0.92, 0.79, 0.82, 0.85, 0.83, 0.96, 0.92, 0.98, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.98, 0.99, 1.0, 1.0]
null
null
null
null
null
null
null
null
null
null
null
71.837596
0.496607
73.069844
0.536075
2,299
O70263
Q9QZS3
22199232
UbiNet, UbiBrowser
Lnx1
MNQPDLADDPDPSPEPLCIVCGQNHSPEENHFYTYTEDVDDDLICHICLQALLDPLDTPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSSILVNKLLNKLLVTCPFTEHCTEVLQRCDLQHHFQTSCKGASHYGLTKDRKRRSQDGCPDGCASLMATTLSPEVSAAATISLMTDEPGLDNPAYVSSVEDGEPVANSSDSGRSNRTRARPFERSTMRSRSFKKINRALSALRRTKSGSVVANHVDQGRDNSENTTVPEVFPRLFHLIPDGEITSIKINRADPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDISNVPHNYAVRLLRQPCQVLRLTVLREQKFRSRSNAHVPDSYGPRDDSFHVILNKSSPEEQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDLRFGSPESAAHLIQASERRVHLVVSRQVRQSSPDIFQEAGWISNGQQSPGPGERNTASKPAATCHEKVVSVWKDPSESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIELTEVSRTEAVAILKSAPSSVVLKALEVKEQEAQEDCSPAALDSNHNVTPPGDWSPSWVMWLELPQYLCNCKDVILRRNTAGSLGFCIVGGYEEYSGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARMLKELKGRITLTIASWPGTFL
Mus musculus
Cytoplasm
Not found
{}
3VQF, 3VQG
{}
Numb
MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQLQDAKKAETDKTVVGPSVAPGNTAPSPSSPTSPTPDGTASSEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDFPIKNTVPEVEGEAESISSLCSQITSAFSTPSEDPFSSAPMTKPVTLVAPQSPVLQANGTDSASHVLTAKPANTALAHVAMPVRETNPWAHVPDAANKEIAAIHPGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQVSAAPLQPVLQPPPPAAIAPPAPPFQGHAFLTSQPVPVGVVPPLQPAFVPTQSYPVANGMPYPASNVPVVGITPSQMVANVFGTAGHPQTTHPHQSPSLAKQQTFPQYETSSATTSPFFKPPAQHLNGSAAFNGVDNGGLASGNRHAEVPPGTCPVDPFEAQWAALESKSKQRTNPSPTNPFSSDLQKTFEIEL
Mus musculus
Cell membrane, Endosome membrane
Not found
{}
1WJ1, 5YQG
{}
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null
null
null
null
71.837596
0.496607
60.269923
0.724487
1,126
O70479
Q9QUI0
22199232
UbiNet, UbiBrowser
Tnfaip1
MSGDTCLCPASGAKPKISGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQSRQEIQELMAEAKYYLIQGLVSTCQTALQDKKDSYQPVCNIPIITSLREEDRLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQASPSEDEDTFELRDRVRRIHVKRYSTYDDRQLGHQSTHRD
Mus musculus
Cytoplasm, Nucleus, Endosome
Not found
{}
null
{}
Rhoa
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLIL
Mus musculus
Cell membrane, Cytoplasm, cytoskeleton, Cleavage furrow, Cytoplasm, cell cortex, Midbody, Cell projection, lamellipodium, Cell projection, dendrite, Nucleus, Cytoplasm
Not found
{}
4F38, 7U2P
{}
[33.3, 39.29, 34.48, 38.43, 37.07, 34.05, 34.18, 30.58, 38.94, 42.42, 42.25, 42.63, 52.37, 60.88, 70.43, 75.75, 73.93, 72.28, 61.58, 68.37, 62.17, 51.44, 49.04, 53.7, 61.46, 66.04, 73.25, 86.94, 91.53, 92.98, 94.74, 96.93, 97.2, 97.51, 95.08, 95.07, 97.17, 97.03, 96.97, 95.34, 94.53, 92.61, 92.45, 92.04, 92.16, 93.84, 92.23, 91.29, 91.65, 93.19, 95.45, 94.57, 94.84, 93.87, 92.47, 92.15, 90.85, 86.56, 84.15, 86.21, 87.97, 88.27, 91.32, 92.97, 93.62, 92.87, 90.36, 90.9, 89.97, 94.89, 94.79, 96.23, 95.8, 95.23, 96.35, 94.36, 95.35, 95.52, 95.91, 96.77, 95.38, 95.25, 96.31, 95.39, 94.34, 95.72, 94.79, 93.17, 90.25, 88.74, 87.42, 88.84, 88.64, 89.6, 89.94, 85.38, 87.1, 87.87, 90.84, 94.33, 95.16, 95.38, 97.02, 97.15, 97.3, 97.75, 97.56, 97.14, 97.88, 97.54, 97.23, 97.12, 96.78, 94.75, 94.07, 95.52, 96.7, 95.85, 94.64, 95.5, 94.42, 92.78, 90.61, 90.33, 87.74, 84.29, 77.65, 74.7, 72.26, 71.96, 74.72, 74.34, 82.17, 82.85, 89.41, 92.11, 96.21, 96.58, 96.42, 94.72, 91.17, 94.02, 93.82, 95.25, 94.86, 95.41, 95.54, 96.25, 96.4, 95.29, 93.41, 92.37, 93.28, 91.68, 94.9, 97.17, 97.95, 98.46, 98.05, 98.35, 96.1, 93.42, 88.5, 78.5, 80.06, 73.09, 71.79, 79.1, 81.76, 83.37, 89.32, 90.44, 90.78, 93.85, 93.79, 92.81, 96.17, 96.74, 94.99, 96.48, 98.29, 98.04, 97.61, 98.18, 98.6, 98.51, 97.31, 97.77, 98.31, 97.64, 95.95, 96.49, 95.99, 93.61, 91.69, 94.9, 96.71, 97.11, 98.28, 97.97, 97.5, 95.24, 89.82, 89.7, 87.87, 88.09, 89.33, 91.83, 94.98, 96.35, 98.46, 97.95, 98.37, 97.18, 94.37, 91.09, 90.47, 91.88, 95.44, 95.63, 97.24, 97.26, 97.56, 95.13, 95.49, 92.3, 91.3, 88.34, 88.97, 87.12, 81.96, 84.37, 82.94, 85.46, 88.31, 90.76, 91.0, 92.76, 94.27, 95.76, 97.1, 96.83, 97.55, 96.88, 96.82, 98.25, 97.62, 96.94, 97.68, 97.75, 96.69, 95.9, 95.6, 94.64, 91.76, 90.11, 84.87, 71.76, 58.57, 55.3, 55.07, 54.43, 57.94, 60.31, 60.2, 58.53, 59.75, 63.29, 59.62, 59.5, 52.87, 43.79, 43.1, 40.61, 40.27, 36.09, 36.52, 33.44, 42.57, 41.44, 41.55, 45.4, 43.0, 44.3, 41.93, 40.46, 43.07, 49.75, 54.42, 62.44, 80.26, 85.14, 89.47, 88.88, 85.35, 79.99, 71.06, 55.96, 50.27, 40.07, 41.58, 38.38, 37.76, 36.46, 35.08, 37.53, 37.08, 36.52, 37.7, 38.41, 36.47, 40.44, 41.64, 37.75, 39.72, 48.39]
[1.0, 1.0, 1.0, 0.92, 0.88, 0.79, 0.84, 0.84, 0.9, 0.94, 0.87, 0.83, 0.62, 0.92, 0.59, 0.73, 0.64, 0.46, 0.63, 0.22, 0.86, 0.22, 0.88, 0.92, 0.31, 0.39, 0.72, 0.54, 0.73, 0.1, 0.3, 0.0, 0.23, 0.0, 0.64, 0.69, 0.31, 0.58, 0.2, 0.57, 0.02, 0.24, 0.05, 0.68, 0.09, 0.0, 0.3, 0.57, 0.23, 0.69, 0.08, 0.13, 0.0, 0.29, 0.14, 0.08, 0.01, 0.43, 0.42, 0.64, 0.39, 0.77, 0.05, 0.41, 0.21, 0.34, 0.77, 0.74, 0.48, 0.12, 0.05, 0.31, 0.07, 0.95, 0.44, 0.54, 0.04, 0.65, 0.11, 0.0, 0.26, 0.31, 0.0, 0.02, 0.47, 0.11, 0.0, 0.44, 0.56, 0.44, 0.59, 0.28, 0.93, 0.3, 0.24, 0.87, 0.39, 0.43, 0.64, 0.37, 0.01, 0.43, 0.28, 0.0, 0.16, 0.49, 0.17, 0.0, 0.48, 0.34, 0.0, 0.48, 0.02, 0.67, 0.45, 0.0, 0.09, 0.51, 0.36, 0.0, 0.51, 0.51, 0.15, 0.08, 0.51, 0.6, 0.33, 0.72, 0.69, 0.44, 0.83, 0.82, 0.37, 0.75, 0.26, 0.69, 0.32, 0.26, 0.53, 0.01, 0.69, 0.45, 0.64, 0.84, 0.24, 0.13, 0.52, 0.65, 0.2, 0.07, 0.74, 0.69, 0.2, 0.65, 0.45, 0.0, 0.02, 0.0, 0.07, 0.0, 0.1, 0.29, 0.16, 0.52, 0.81, 0.46, 0.24, 0.96, 0.42, 0.4, 0.26, 0.21, 0.89, 0.52, 0.02, 0.42, 0.55, 0.25, 0.03, 0.52, 0.43, 0.0, 0.23, 0.49, 0.09, 0.0, 0.37, 0.54, 0.05, 0.02, 0.65, 0.9, 0.12, 0.42, 0.56, 0.4, 0.07, 0.23, 0.02, 0.0, 0.15, 0.03, 0.43, 0.38, 0.17, 0.73, 0.5, 0.08, 0.0, 0.06, 0.0, 0.04, 0.0, 0.05, 0.01, 0.66, 0.37, 0.29, 0.36, 0.06, 0.0, 0.26, 0.0, 0.16, 0.01, 0.22, 0.33, 0.4, 0.33, 0.69, 0.48, 1.0, 0.98, 0.55, 0.44, 0.23, 0.03, 0.35, 0.01, 0.18, 0.24, 0.15, 0.51, 0.71, 0.31, 0.0, 0.48, 0.46, 0.0, 0.01, 0.4, 0.26, 0.02, 0.18, 0.83, 0.23, 0.37, 0.6, 0.85, 0.89, 0.89, 0.58, 0.6, 0.59, 0.59, 0.67, 0.53, 0.74, 0.74, 0.67, 0.69, 0.89, 0.89, 0.85, 0.89, 0.97, 0.74, 0.93, 0.94, 0.76, 0.9, 0.58, 0.78, 0.73, 0.52, 0.71, 0.71, 0.78, 0.67, 0.69, 0.8, 0.27, 0.39, 0.69, 0.2, 0.7, 0.34, 0.86, 0.84, 0.88, 0.71, 0.89, 0.86, 0.97, 0.91, 0.91, 0.91, 0.9, 0.7, 0.92, 0.87, 0.87, 0.85, 0.91, 0.95, 0.98]
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null
null
null
null
null
null
null
null
null
null
null
81.424399
0.446203
93.657565
0.340518
2,576
O70481
O08850
null
degron_data
Ubr1
MADEEMDGAERMDVSPEPPLAPQRPASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQEESVQMSILTPLEWYLFGEDPDICLEKLKHSGAFQLCGKVFKSGETTYSCRDCAIDPTCVLCMDCFQSSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCVDHEPGRAGTTKESLHCPLNEEVIAQARRIFPSVIKYIVEMTIWEEEKELPPELQIREKNERYYCVLFNDEHHSYDHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAGVYATCQEAKEDIKSHSENVSQHPLHVEVLHSVVMAHQKFALRLGSWMNKIMSYSSDFRQIFCQACLVEEPGSENPCLISRLMLWDAKLYKGARKILHELIFSSFFMEMEYKKLFAMEFVKYYKQLQKEYISDDHERSISITALSVQMLTVPTLARHLIEEQNVISVITETLLEVLPEYLDRNNKFNFQGYSQDKLGRVYAVICDLKYILISKPVIWTERLRAQFLEGFRSFLKILTCMQGMEEIRRQVGQHIEVDPDWEAAIAIQMQLKNILLMFQEWCACDEDLLLVAYKECHKAVMRCSTNFMSSTKTVVQLCGHSLETKSYKVSEDLVSIHLPLSRTLAGLHVRLSRLGAISRLHEFVPFDGFQVEVLVEYPLRCLVLVAQVVAEMWRRNGLSLISQVFYYQDVKCREEMYDKDIIMLQIGASIMDPNKFLLLVLQRYELTDAFNKTISTKDQDLIKQYNTLIEEMLQVLIYIVGERYVPGVGNVTREEVIMREITHLLCIEPMPHSAIARNLPENENNETGLENVINKVATFKKPGVSGHGVYELKDESLKDFNMYFYHYSKTQHSKAEHMQKKRRKQENKDEALPPPPPPEFCPAFSKVVNLLSCDVMMYILRTIFERAVDMESNLWTEGMLQMAFHILALGLLEEKQQLQKAPEEEVAFDFYHKASRLGSSAMNAQNIQMLLEKLKGIPQLESQKDMITWILQMFDTVKRLREKSCLVVATTSGLECVKSEEITHDKEKAERKRKAEAARLHRQKIMAQMSALQKNFIETHKLMYDNTSEVTGKEDSIMEEESTSAVSEASRIALGPKRGPAVTEKEVLTCILCQEEQEVKLENNAMVLSACVQKSTALTQHRGKPVDHLGETLDPLFMDPDLAHGTYTGSCGHVMHAVCWQKYFEAVQLSSQQRIHVDLFDLESGEYLCPLCKSLCNTVIPIIPLQPQKINSENAEALAQLLTLARWIQTVLARISGYNIKHAKGEAPAVPVLFNQGMGDSTFEFHSILSFGVQSSVKYSNSIKEMVILFATTIYRIGLKVPPDELDPRVPMMTWSTCAFTIQAIENLLGDEGKPLFGALQNRQHNGLKALMQFAVAQRTTCPQVLIHKHLARLLSVILPNLQSENTPGLLSVDLFHVLVGAVLAFPSLYWDDTVDLQPSPLSSSYNHLYLFHLITMAHMLQILLTTDTDLSSGPPLAEGEEDSEEARCASAFFVEVSQHTDGLAGCGAPGWYLWLSLRNGITPYLRCAALLFHYLLGVAPPEELFANSAEGEFSALCSYLSLPTNLFLLFQEYWDTIRPLLQRWCGDPALLKSLKQKSAVVRYPRKRNSLIELPEDYSCLLNQASHFRCPRSADDERKHPVLCLFCGAILCSQNICCQEIVNGEEVGACVFHALHCGAGVCIFLKIRECRVVLVEGKARGCAYPAPYLDEYGETDPGLKRGNPLHLSRERYRKLHLVWQQHCIIEEIARSQETNQMLFGFNWQLL
Mus musculus
Cytoplasm, cytosol
Not found
{}
null
{}
Rgs5
MCKGLAALPHSCLERAKEIKIKLGILLQKPDSAVDLVIPYNEKPEKPAKAHKPSLEEVLQWRQSLDKLLQNSYGFASFKSFLKSEFSEENLEFWVACENYKKIKSPIKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSPRSFDLAQKRIYALMEKDSLPRFVRSEFYKELIK
Mus musculus
Cytoplasm, Membrane
Not found
{}
null
{}
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degron_data
Ubr1
MADEEMDGAERMDVSPEPPLAPQRPASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQEESVQMSILTPLEWYLFGEDPDICLEKLKHSGAFQLCGKVFKSGETTYSCRDCAIDPTCVLCMDCFQSSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCVDHEPGRAGTTKESLHCPLNEEVIAQARRIFPSVIKYIVEMTIWEEEKELPPELQIREKNERYYCVLFNDEHHSYDHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAGVYATCQEAKEDIKSHSENVSQHPLHVEVLHSVVMAHQKFALRLGSWMNKIMSYSSDFRQIFCQACLVEEPGSENPCLISRLMLWDAKLYKGARKILHELIFSSFFMEMEYKKLFAMEFVKYYKQLQKEYISDDHERSISITALSVQMLTVPTLARHLIEEQNVISVITETLLEVLPEYLDRNNKFNFQGYSQDKLGRVYAVICDLKYILISKPVIWTERLRAQFLEGFRSFLKILTCMQGMEEIRRQVGQHIEVDPDWEAAIAIQMQLKNILLMFQEWCACDEDLLLVAYKECHKAVMRCSTNFMSSTKTVVQLCGHSLETKSYKVSEDLVSIHLPLSRTLAGLHVRLSRLGAISRLHEFVPFDGFQVEVLVEYPLRCLVLVAQVVAEMWRRNGLSLISQVFYYQDVKCREEMYDKDIIMLQIGASIMDPNKFLLLVLQRYELTDAFNKTISTKDQDLIKQYNTLIEEMLQVLIYIVGERYVPGVGNVTREEVIMREITHLLCIEPMPHSAIARNLPENENNETGLENVINKVATFKKPGVSGHGVYELKDESLKDFNMYFYHYSKTQHSKAEHMQKKRRKQENKDEALPPPPPPEFCPAFSKVVNLLSCDVMMYILRTIFERAVDMESNLWTEGMLQMAFHILALGLLEEKQQLQKAPEEEVAFDFYHKASRLGSSAMNAQNIQMLLEKLKGIPQLESQKDMITWILQMFDTVKRLREKSCLVVATTSGLECVKSEEITHDKEKAERKRKAEAARLHRQKIMAQMSALQKNFIETHKLMYDNTSEVTGKEDSIMEEESTSAVSEASRIALGPKRGPAVTEKEVLTCILCQEEQEVKLENNAMVLSACVQKSTALTQHRGKPVDHLGETLDPLFMDPDLAHGTYTGSCGHVMHAVCWQKYFEAVQLSSQQRIHVDLFDLESGEYLCPLCKSLCNTVIPIIPLQPQKINSENAEALAQLLTLARWIQTVLARISGYNIKHAKGEAPAVPVLFNQGMGDSTFEFHSILSFGVQSSVKYSNSIKEMVILFATTIYRIGLKVPPDELDPRVPMMTWSTCAFTIQAIENLLGDEGKPLFGALQNRQHNGLKALMQFAVAQRTTCPQVLIHKHLARLLSVILPNLQSENTPGLLSVDLFHVLVGAVLAFPSLYWDDTVDLQPSPLSSSYNHLYLFHLITMAHMLQILLTTDTDLSSGPPLAEGEEDSEEARCASAFFVEVSQHTDGLAGCGAPGWYLWLSLRNGITPYLRCAALLFHYLLGVAPPEELFANSAEGEFSALCSYLSLPTNLFLLFQEYWDTIRPLLQRWCGDPALLKSLKQKSAVVRYPRKRNSLIELPEDYSCLLNQASHFRCPRSADDERKHPVLCLFCGAILCSQNICCQEIVNGEEVGACVFHALHCGAGVCIFLKIRECRVVLVEGKARGCAYPAPYLDEYGETDPGLKRGNPLHLSRERYRKLHLVWQQHCIIEEIARSQETNQMLFGFNWQLL
Mus musculus
Cytoplasm, cytosol
Not found
{}
null
{}
Rgs4
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHSSSHSKKDKVVTCQRVSQEEVKKWAESLENLIHHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLQPTITCFDEAQKKIFNLMERDSYRRFLKSRFYLDLTNPSSCGAEKQKGAKSSADCTSLVSQCA
Mus musculus
null
Not found
{}
null
{}
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[56.66, 48.25, 50.09, 61.51, 57.68, 57.82, 50.93, 56.12, 56.89, 54.9, 45.79, 43.51, 51.52, 48.44, 48.33, 49.01, 51.53, 47.31, 58.08, 55.59, 60.56, 54.64, 55.38, 46.13, 56.91, 57.34, 47.58, 50.6, 40.5, 45.85, 39.3, 43.45, 33.16, 36.38, 46.46, 40.57, 40.98, 47.7, 42.19, 47.86, 47.57, 47.43, 52.52, 48.71, 52.16, 53.81, 46.56, 56.28, 60.54, 73.25, 85.61, 89.61, 89.29, 91.4, 92.53, 93.27, 93.73, 95.31, 96.26, 95.18, 96.27, 97.14, 98.0, 97.5, 96.81, 97.52, 97.39, 95.97, 95.84, 94.52, 93.68, 95.91, 97.24, 96.31, 96.23, 98.01, 97.99, 97.57, 98.2, 98.26, 97.88, 97.24, 97.05, 96.59, 97.75, 98.09, 98.47, 98.34, 98.41, 98.46, 98.67, 98.55, 98.15, 98.24, 98.29, 97.72, 96.97, 97.99, 97.31, 96.56, 95.98, 92.56, 91.31, 87.46, 92.09, 94.97, 94.88, 95.34, 96.86, 97.64, 97.83, 97.57, 97.95, 98.45, 98.32, 98.1, 98.37, 98.59, 98.22, 96.76, 95.79, 95.22, 97.09, 96.38, 97.74, 97.74, 98.28, 97.19, 97.25, 96.21, 96.94, 97.39, 97.71, 97.98, 97.36, 98.11, 97.93, 97.6, 97.78, 97.17, 96.81, 95.88, 94.79, 95.48, 95.82, 96.57, 96.61, 97.25, 98.35, 98.26, 98.33, 98.47, 98.55, 98.35, 98.27, 98.33, 98.5, 98.13, 97.81, 98.17, 98.22, 97.2, 96.48, 97.73, 98.35, 97.36, 98.06, 98.22, 97.18, 96.35, 96.26, 94.83, 93.97, 94.77, 93.49, 90.23, 88.42, 85.53, 79.87, 66.81, 59.32, 52.87, 45.71, 41.99, 39.54, 44.22, 37.3, 40.08, 37.03, 37.79, 46.43, 46.14, 46.49, 47.23, 52.36, 45.52, 48.88, 49.44, 54.94, 55.89, 49.14, 54.54, 52.95, 50.66, 50.0]
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null
null
null
null
null
null
null
null
null
null
null
84.045623
0.307018
79.006049
0.563171
341
O70481
P15409
22199232
UbiNet, UbiBrowser
Ubr1
MADEEMDGAERMDVSPEPPLAPQRPASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQEESVQMSILTPLEWYLFGEDPDICLEKLKHSGAFQLCGKVFKSGETTYSCRDCAIDPTCVLCMDCFQSSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCVDHEPGRAGTTKESLHCPLNEEVIAQARRIFPSVIKYIVEMTIWEEEKELPPELQIREKNERYYCVLFNDEHHSYDHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAGVYATCQEAKEDIKSHSENVSQHPLHVEVLHSVVMAHQKFALRLGSWMNKIMSYSSDFRQIFCQACLVEEPGSENPCLISRLMLWDAKLYKGARKILHELIFSSFFMEMEYKKLFAMEFVKYYKQLQKEYISDDHERSISITALSVQMLTVPTLARHLIEEQNVISVITETLLEVLPEYLDRNNKFNFQGYSQDKLGRVYAVICDLKYILISKPVIWTERLRAQFLEGFRSFLKILTCMQGMEEIRRQVGQHIEVDPDWEAAIAIQMQLKNILLMFQEWCACDEDLLLVAYKECHKAVMRCSTNFMSSTKTVVQLCGHSLETKSYKVSEDLVSIHLPLSRTLAGLHVRLSRLGAISRLHEFVPFDGFQVEVLVEYPLRCLVLVAQVVAEMWRRNGLSLISQVFYYQDVKCREEMYDKDIIMLQIGASIMDPNKFLLLVLQRYELTDAFNKTISTKDQDLIKQYNTLIEEMLQVLIYIVGERYVPGVGNVTREEVIMREITHLLCIEPMPHSAIARNLPENENNETGLENVINKVATFKKPGVSGHGVYELKDESLKDFNMYFYHYSKTQHSKAEHMQKKRRKQENKDEALPPPPPPEFCPAFSKVVNLLSCDVMMYILRTIFERAVDMESNLWTEGMLQMAFHILALGLLEEKQQLQKAPEEEVAFDFYHKASRLGSSAMNAQNIQMLLEKLKGIPQLESQKDMITWILQMFDTVKRLREKSCLVVATTSGLECVKSEEITHDKEKAERKRKAEAARLHRQKIMAQMSALQKNFIETHKLMYDNTSEVTGKEDSIMEEESTSAVSEASRIALGPKRGPAVTEKEVLTCILCQEEQEVKLENNAMVLSACVQKSTALTQHRGKPVDHLGETLDPLFMDPDLAHGTYTGSCGHVMHAVCWQKYFEAVQLSSQQRIHVDLFDLESGEYLCPLCKSLCNTVIPIIPLQPQKINSENAEALAQLLTLARWIQTVLARISGYNIKHAKGEAPAVPVLFNQGMGDSTFEFHSILSFGVQSSVKYSNSIKEMVILFATTIYRIGLKVPPDELDPRVPMMTWSTCAFTIQAIENLLGDEGKPLFGALQNRQHNGLKALMQFAVAQRTTCPQVLIHKHLARLLSVILPNLQSENTPGLLSVDLFHVLVGAVLAFPSLYWDDTVDLQPSPLSSSYNHLYLFHLITMAHMLQILLTTDTDLSSGPPLAEGEEDSEEARCASAFFVEVSQHTDGLAGCGAPGWYLWLSLRNGITPYLRCAALLFHYLLGVAPPEELFANSAEGEFSALCSYLSLPTNLFLLFQEYWDTIRPLLQRWCGDPALLKSLKQKSAVVRYPRKRNSLIELPEDYSCLLNQASHFRCPRSADDERKHPVLCLFCGAILCSQNICCQEIVNGEEVGACVFHALHCGAGVCIFLKIRECRVVLVEGKARGCAYPAPYLDEYGETDPGLKRGNPLHLSRERYRKLHLVWQQHCIIEEIARSQETNQMLFGFNWQLL
Mus musculus
Cytoplasm, cytosol
Not found
{}
null
{}
Rho
MNGTEGPNFYVPFSNVTGVVRSPFEQPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVVFTWIMALACAAPPLVGWSRYIPEGMQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIFFLICWLPYASVAFYIFTHQGSNFGPIFMTLPAFFAKSSSIYNPVIYIMLNKQFRNCMLTTLCCGKNPLGDDDASATASKTETSQVAPA
Mus musculus
Membrane, Cell projection, cilium, photoreceptor outer segment
Not found
{}
null
{}
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degron_data
Ubr1
MADEEMDGAERMDVSPEPPLAPQRPASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQEESVQMSILTPLEWYLFGEDPDICLEKLKHSGAFQLCGKVFKSGETTYSCRDCAIDPTCVLCMDCFQSSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCVDHEPGRAGTTKESLHCPLNEEVIAQARRIFPSVIKYIVEMTIWEEEKELPPELQIREKNERYYCVLFNDEHHSYDHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAGVYATCQEAKEDIKSHSENVSQHPLHVEVLHSVVMAHQKFALRLGSWMNKIMSYSSDFRQIFCQACLVEEPGSENPCLISRLMLWDAKLYKGARKILHELIFSSFFMEMEYKKLFAMEFVKYYKQLQKEYISDDHERSISITALSVQMLTVPTLARHLIEEQNVISVITETLLEVLPEYLDRNNKFNFQGYSQDKLGRVYAVICDLKYILISKPVIWTERLRAQFLEGFRSFLKILTCMQGMEEIRRQVGQHIEVDPDWEAAIAIQMQLKNILLMFQEWCACDEDLLLVAYKECHKAVMRCSTNFMSSTKTVVQLCGHSLETKSYKVSEDLVSIHLPLSRTLAGLHVRLSRLGAISRLHEFVPFDGFQVEVLVEYPLRCLVLVAQVVAEMWRRNGLSLISQVFYYQDVKCREEMYDKDIIMLQIGASIMDPNKFLLLVLQRYELTDAFNKTISTKDQDLIKQYNTLIEEMLQVLIYIVGERYVPGVGNVTREEVIMREITHLLCIEPMPHSAIARNLPENENNETGLENVINKVATFKKPGVSGHGVYELKDESLKDFNMYFYHYSKTQHSKAEHMQKKRRKQENKDEALPPPPPPEFCPAFSKVVNLLSCDVMMYILRTIFERAVDMESNLWTEGMLQMAFHILALGLLEEKQQLQKAPEEEVAFDFYHKASRLGSSAMNAQNIQMLLEKLKGIPQLESQKDMITWILQMFDTVKRLREKSCLVVATTSGLECVKSEEITHDKEKAERKRKAEAARLHRQKIMAQMSALQKNFIETHKLMYDNTSEVTGKEDSIMEEESTSAVSEASRIALGPKRGPAVTEKEVLTCILCQEEQEVKLENNAMVLSACVQKSTALTQHRGKPVDHLGETLDPLFMDPDLAHGTYTGSCGHVMHAVCWQKYFEAVQLSSQQRIHVDLFDLESGEYLCPLCKSLCNTVIPIIPLQPQKINSENAEALAQLLTLARWIQTVLARISGYNIKHAKGEAPAVPVLFNQGMGDSTFEFHSILSFGVQSSVKYSNSIKEMVILFATTIYRIGLKVPPDELDPRVPMMTWSTCAFTIQAIENLLGDEGKPLFGALQNRQHNGLKALMQFAVAQRTTCPQVLIHKHLARLLSVILPNLQSENTPGLLSVDLFHVLVGAVLAFPSLYWDDTVDLQPSPLSSSYNHLYLFHLITMAHMLQILLTTDTDLSSGPPLAEGEEDSEEARCASAFFVEVSQHTDGLAGCGAPGWYLWLSLRNGITPYLRCAALLFHYLLGVAPPEELFANSAEGEFSALCSYLSLPTNLFLLFQEYWDTIRPLLQRWCGDPALLKSLKQKSAVVRYPRKRNSLIELPEDYSCLLNQASHFRCPRSADDERKHPVLCLFCGAILCSQNICCQEIVNGEEVGACVFHALHCGAGVCIFLKIRECRVVLVEGKARGCAYPAPYLDEYGETDPGLKRGNPLHLSRERYRKLHLVWQQHCIIEEIARSQETNQMLFGFNWQLL
Mus musculus
Cytoplasm, cytosol
Not found
{}
null
{}
Rgs16
MCRTLATFPNTCLERAKEFKTRLGIFLHKSELSSDTGGISKFEWASKHNKERSFSEDVLGWRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASATSTSAPSGSPAEPSHT
Mus musculus
Membrane
Not found
{}
3C7K, 3C7L
{}
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null
null
null
null
null
null
null
null
null
null
null
84.045623
0.307018
81.74806
0.513184
341
O70583
P07978
22199232
UbiNet, UbiBrowser
Mid1
METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNEPVESINAFQCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMSSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVIRLRKLAQQIANCKQCLERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPAIREELCTASYDTITVHWTSEDEFSVVSYELQYTIFTGQANVVNVACDGTCLLGSAGLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFTVKAINQAGSRSSEPGKLKTNSQPFRLDPKSAHRKLKVSHDNLTVERDESSSKKSHAPERFAGQGSYGVAGNVFIDSGRHYWEVVTSGSTWYAIGLAYRSAPKHEWIGKNAASWALCRCHNHWAVRHDGKETPIAPAPHLRRVGVLLDYDNGSIAFYDALSSVHLHTFHAALAQPVCPTFTVWNKCLTIVTGLPIPDHLDCTEQRP
Mus musculus
Cytoplasm, Cytoplasm, cytoskeleton
Not found
{}
null
{}
Prm2
MVRYRMRSPSEGPHQGPGQDHEREEQGQGQGLSPERVEDYGRTHRGHHHHRHRRCSRKRLHRIHKRRRSCRRRRRHSCRHRRRHRRGCRRSRRRRRCRCRKCRRHHH
Mus musculus
Nucleus, Chromosome
Not found
{}
null
{}
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null
null
null
null
null
null
null
null
null
null
null
84.171279
0.438897
52.048879
0.804112
2,976
O74757
Q9UUD1
22199232
UbiNet, UbiBrowser
hrd1
MKFILYVLASLVLFGLSVLLSLYSSANVYSATVMISQSPVHITIGLNVCLCLFFAIANALKTLLFGSLQTFELELLYEQFWITLTEIMLAITVFREAISISFFMLLSTLMFARVFHSICSFRTERLQIQLTDQRFHIFSRLTCAYFVLSILDASLIYLCFTSEHLGDKSTRMLFVCEFSVLLLNLTIEASKLCIYLYEARHLDQVWDEKSTYLFRLEVCRDGLRLLAYSLLFMYQFPYVSVPIYSIRQMYTCFYSLFRRIREHARFRQATRDMNAMYPTATEEQLTNSDRTCTICREEMFHPDHPPENTDEMEPLPRGLDMTPKRLPCGHILHFHCLRNWLERQQTCPICRRSVIGNQSSPTGIPASPNVRATQIATQVPNPQNTPTTTAVPGITNSSNQGDPQASTFNGVPNANSSGFAAHTQDLSSVIPRRIALRDGWTMLPIPGTRRIPTYSQSTSTTNPSATPTTGDPSNSTYGGPQTFPNSGNNPNFNRGIAGIVPPGWRLVSSNTQSLSTNSAMTSLYQNASSADNNLGSSLPNVVPLSRGLTQSNETSNTFPAASSNISSQLRELHTKIDELRETVSNFRADYNSIRTSLNQLEAASGINERIQTTSADSLLNSNGMSGTEGFENTQTSITTNDNQSSILTSSDQTSPFATDEDRQNSRNVQLETVDENF
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Endoplasmic reticulum membrane
Not found
{}
null
{}
sre1
MQSSIPSVSVSVASPAMETPTKASPDSKSPNSVGAIPSSSPLASSTKASTSTPFVENCSNLLCDLASIVEDSPPTLTNTSLSPHSFSLSDMESSMSNWLNPFAFDNTMNSAPPLFTSTNMGSPNSLENSTNPLLSNCGSPNSFQNETFTGPSLNEFDADDKIQRQMKILHSVDTIDPSTVQNYPSADMSNPEVKLKTEEIITPMDTTCKPEPSAKKIKLSPSSEDSCSIPETLPFSAPKSRGSLSPSETPDFVAGPGGKPKKTAHNMIEKRYRTNLNDRICELRDAVPSLRAAAALRCGNSLDDEDLGGLTPARKLNKGTILAKATEYIRHLEAKNKELQKTNKQLSDRLAFYEDPSMAPPSNDTRAVNSVNVVSSSDYSVHQSSRPNLTQRAFTSPTLNTMGRTALNGMVGLGLFNYFGNDSSQSVYGLFALPPFLMSPFTGTVLFNMLKIGVVLLGLFYLLHDNSLFKGFKGEKKSKVSTRSSMSPSSILFRKTVFEKYCLLDHSTSTISLFFGLLIFTLKSAYGYLTHRLSALYTSSENWVYSEQQLAEVRNMEKLLDAQLMGGDAKVDRLRLLMVFASSFSLPPSSHTCALQAMYCQLIFSNTSVPSAIVSKCVAFFWNAAKKQHSKSSVHAELRELPECTANLIENSHADDVFSPNMVERLWVLAKCTRDSAQMSDSIISSLSDVLVLSPLEVLASWYAADLLDALLMESLSRKVEISEIEEIISLCPKNSSIIRHALLAKLVLFPENTADSLNEVLAAYKNTLDLCSQDKRKQSSVLKINLSKLFTLHSCLSLALQRLGYGDVSKRMYQEIFVPDSDADITPLSFIISWTALNTFAPICTSPKENDVVEKMAMYVRTAIGTLKIQDLKLSRKLINSCIDIGSRLQEDLGYVSSA
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Endoplasmic reticulum membrane, Nucleus
Not found
{}
5GPD, 5GRS
{}
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null
null
null
null
null
null
null
null
null
null
null
64.086499
0.619675
61.070744
0.573678
648
O75150
Q16623
22199232, hUbiquitome
UbiNet, UbiBrowser, 31181401
RNF40
MSGPGNKRAAGDGGSGPPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSSAPEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPPLSEPALAFVVALGASSSEEVELELQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLATKNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAHSTPNLGHPEDSGVSAPAPGKEEGGPGPVSTPDNRKEMAPVPGTTTTTTSVKKEELVPSEEDFQGITPGAQGPSSRGREPEARPKRELREREGPSLGPPPVASALSRADREKAKVEETKRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS
Homo sapiens
Nucleus
Low tissue specificity
{'Ciliated cells': '17.9', 'Basal respiratory cells': '10.3', 'Club cells': '16.3', 'Ionocytes': '9.6', 'Mucus glandular cells': '14.5', 'Serous glandular cells': '14.6', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '22.1', 'Paneth cells': '26.2', 'Distal enterocytes': '30.4', 'Intestinal goblet cells': '25.6', 'Exocrine glandular cells': '-0.664', 'Basal prostatic cells': '26.0', 'Prostatic glandular cells': '18.7', 'Breast glandular cells': '0.601', 'Breast myoepithelial cells': '0.577', 'Glandular and luminal cells': '27.3', 'Secretory cells': '16.8', 'Basal keratinocytes': '19.2', 'Suprabasal keratinocytes': '21.2', 'Basal squamous epithelial cells': '18.0', 'Squamous epithelial cells': '20.6', 'Alveolar cells type 1': '0.193', 'Alveolar cells type 2': '0.263', 'Salivary duct cells': '16.0', 'Ductal cells': '0.618', 'Hepatocytes': '0.565', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.208', 'Distal tubular cells': '64.5', 'Collecting duct cells': '25.3', 'Mesothelial cells': '0.426', 'Sertoli cells': '0.081', 'Granulosa cells': '13.8', 'Enteroendocrine cells': '29.5', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '-0.048', 'Excitatory neurons': '10.0', 'Inhibitory neurons': '10.7', 'Cone photoreceptor cells': '17.0', 'Rod photoreceptor cells': '9.5', 'Bipolar cells': '11.7', 'Horizontal cells': '16.4', 'Astrocytes': '17.3', 'Oligodendrocyte precursor cells': '12.3', 'Oligodendrocytes': '8.0', 'Microglial cells': '4.5', 'Muller glia cells': '16.6', 'Schwann cells': '0.053', 'Spermatogonia': '0.256', 'Spermatocytes': '0.525', 'Early spermatids': '0.441', 'Late spermatids': '0.100', 'Oocytes': '14.0', 'Cytotrophoblasts': '16.2', 'Syncytiotrophoblasts': '20.6', 'Extravillous trophoblasts': '16.0', 'Endothelial cells': '16.3', 'Lymphatic endothelial cells': '13.5', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '-0.278', 'Smooth muscle cells': '14.8', 'Adipocytes': '12.9', 'Melanocytes': '0.259', 'Fibroblasts': '14.8', 'Peritubular cells': '-0.022', 'Endometrial stromal cells': '19.9', 'Ovarian stromal cells': '14.0', 'Undifferentiated cells': '22.9', 'T-cells': '16.4', 'B-cells': '17.4', 'Plasma cells': '20.0', 'Nk-cells': '16.3', 'Granulocytes': '8.8', 'Monocytes': '17.6', 'Macrophages': '18.8', 'Hofbauer cells': '20.7', 'Kupffer cells': '20.4', 'Dendritic cells': '18.3', 'Langerhans cells': '0.357', 'Erythroid cells': '-0.165', 'Adipocytes (Subcutaneous)': '-0.241', 'Adipocytes (Visceral)': '-0.070', 'Breast glandular cells (progenitors)': '0.525', 'Adipocytes (Breast)': '-0.522', 'Colon enterocytes': '0.060', 'Colon enteroendocrine cells': '0.199', 'Enteric glia cells': '-0.333', 'Mitotic cells (Colon)': '0.017', 'Mitotic cells (Heart)': '0.487', 'Podocytes': '-0.142', 'Ascending Loop of Henle cells': '0.480', 'Intercalated cells': '0.015', 'Cholangiocyte': '0.343', 'NK-cells (Liver)': '-0.361', 'Respiratory ciliated cells': '-0.021', 'Mitotic cells (Lung)': '0.064', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.177', 'Alpha cells': '0.421', 'Beta cells': '0.208', 'Prostate glandular cells': '0.231', 'Prostate basal glandular cells': '0.379', 'Urothelial cells': '0.144', 'Keratinocyte (other)': '0.412', 'Keratinocyte (granular)': '0.060', 'Hair cortex cells': '-0.020', 'Inner root sheath cells': '-0.005', 'Outer root sheath cells': '0.092', 'Sebaceous gland cells': '0.034', 'Eccrine sweat gland cells': '-0.115', 'Adipocytes (Skin)': '-0.134', 'Mitotic cells (Skin)': '0.294', 'Parietal cells': '-0.521', 'Chief cells': '-0.459', 'Gastric mucous cells': '-0.223', 'Gastric enteroendocrine cells': '-0.355', 'Mitotic cells (Stomach)': '0.171', 'Parafollicular cells': '0.135', 'Thyroid glandular cells': '0.508', 'Mitotic cells (Thyroid)': '-0.079', 'Adrenal cortex cells': '0.597', 'Adrenal medulla cells': '0.033', 'Mitotic cells (Adrenal gland)': '0.445', 'Minor salivary glandular cells': '0.475', 'Minor salivary gland ductal cells': '0.114', 'Minor salivary gland basal cells': '0.410', 'Mitotic cells (Minor salivary gland)': '0.369', 'Adipocytes (Minor salivary gland)': '0.171', 'Somatotropes': '-0.052', 'Lactotropes': '-0.082', 'Gonadotropes': '0.059', 'Corticotropes': '-0.087', 'Thyrotropes': '0.020', 'Undifferentiated cells (Pituitary gland)': '0.313', 'Mitotic cells (Spleen)': '-0.010', 'Platelets': '-0.035', 'Erythrocytes': '-0.068', 'Hematopoietic stem cells': '-0.175', 'B-cells (Spleen)': '0.282', 'NK-cells (Spleen)': '0.212', 'Amygdala excitatory': '15.9', 'Cerebellar inhibitory': '16.9', 'Cge interneuron': '17.8', 'Deep-layer corticothalamic and 6b': '15.2', 'Deep-layer intratelencephalic': '15.1', 'Deep-layer near-projecting': '16.1', 'Eccentric medium spiny neuron': '16.9', 'Hippocampal ca1-3': '18.4', 'Hippocampal ca4': '16.8', 'Hippocampal dentate gyrus': '13.9', 'Lamp5-lhx6 and chandelier': '17.2', 'Lower rhombic lip': '10.6', 'Mammillary body': '12.5', 'Medium spiny neuron': '15.9', 'Mge interneuron': '17.6', 'Midbrain-derived inhibitory': '18.7', 'Miscellaneous': '16.2', 'Splatter': '14.0', 'Thalamic excitatory': '16.0', 'Upper rhombic lip': '16.0', 'Upper-layer intratelencephalic': '15.1', 'Astrocyte': '22.9', 'Bergmann glia': '21.5', 'Central nervous system macrophage': '17.7', 'Choroid plexus epithelial cell': '12.2', 'Committed oligodendrocyte precursor': '19.3', 'Ependymal cell': '19.0', 'Oligodendrocyte': '11.2', 'Oligodendrocyte precursor cell': '17.7', 'Endothelial cell': '16.8', 'Pericyte': '19.8', 'Vascular associated smooth muscle cell': '17.8', 'Fibroblast': '17.6', 'Leukocyte': '16.3', 'Basophil': '88.5', 'Eosinophil': '17.2', 'Neutrophil': '140.5', 'Classical monocyte': '33.0', 'Non-classical monocyte': '24.4', 'Intermediate monocyte': '86.7', 'T-reg': '52.8', 'GdT-cell': '13.2', 'MAIT T-cell': '79.6', 'Memory CD4 T-cell': '7.2', 'Naive CD4 T-cell': '18.0', 'Memory CD8 T-cell': '10.0', 'Naive CD8 T-cell': '24.5', 'Memory B-cell': '8.1', 'Naive B-cell': '16.9', 'Plasmacytoid DC': '68.0', 'Myeloid DC': '69.2', 'NK-cell': '38.9', 'Total PBMC': '59.4', 'Vd2 gdTCR': '70.5', 'Memory CD4 T-cell Th1\\/Th17': '19.1', 'Memory CD4 T-cell Th17': '21.5', 'Memory CD4 T-cell Th2': '22.8', 'Non-Vd2 gdTCR': '78.7', 'Memory CD4 T-cell Th1': '28.1', 'Memory CD4 T-cell TFH': '33.1', 'Terminal effector memory CD4 T-cell': '69.4', 'Central memory CD8 T-cell': '62.9', 'Effector memory CD8 T-cell': '83.9', 'Terminal effector memory CD8 T-cell': '74.8', 'Non-switched memory B-cell': '49.5', 'Plasmablast': '59.3', 'Switched memory B-cell': '59.0', 'Exhausted memory B-cell': '63.9', 'Progenitor cell': '78.3', 'Naive CD4 T-cell activated': '13.9', 'Naive CD8 T-cell activated': '24.6', 'Memory T-reg': '32.7', 'Naive T-reg': '25.3'}
8GUI, 8GUJ, 8IEJ
{'Adipose Tissue': 35.89617940199336, 'Adrenal Gland': 35.863279069767444, 'Bladder': 38.30285714285714, 'Blood': 35.896346609257265, 'Blood Vessel': 42.135866666666665, 'Brain': 24.48113580620742, 'Breast': 40.03095860566449, 'Cervix Uteri': 52.26894736842105, 'Colon': 31.54429396662388, 'Esophagus': 34.059725259515574, 'Fallopian Tube': 48.76555555555555, 'Heart': 13.445284552845528, 'Kidney': 20.505415730337077, 'Liver': 12.66583628318584, 'Lung': 40.21266435986159, 'Muscle': 14.072226650062266, 'Nerve': 48.54226171243942, 'Ovary': 54.63477777777778, 'Pancreas': 14.481707317073171, 'Pituitary': 38.49226148409894, 'Prostate': 39.41742857142857, 'Salivary Gland': 35.94524691358025, 'Skin': 48.537831951354335, 'Small Intestine': 33.137647058823525, 'Spleen': 32.4444398340249, 'Stomach': 27.62590529247911, 'Testis': 73.01493074792243, 'Thyroid': 54.08897396630934, 'Uterus': 54.04042253521126, 'Vagina': 42.33967948717949}
STX1A
MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA
Homo sapiens
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Synapse, synaptosome, Cell membrane, Secreted
Group enriched (brain, pituitary gland)
{'Ciliated cells': '6.3', 'Basal respiratory cells': '6.3', 'Club cells': '5.0', 'Ionocytes': '8.5', 'Mucus glandular cells': '2.1', 'Serous glandular cells': '0.5', 'Gastric mucus-secreting cells': '2.9', 'Proximal enterocytes': '2.9', 'Paneth cells': '0.2', 'Distal enterocytes': '0.6', 'Intestinal goblet cells': '2.3', 'Exocrine glandular cells': '-0.418', 'Basal prostatic cells': '1.9', 'Prostatic glandular cells': '1.0', 'Breast glandular cells': '0.459', 'Breast myoepithelial cells': '0.381', 'Glandular and luminal cells': '9.0', 'Secretory cells': '2.9', 'Basal keratinocytes': '3.0', 'Suprabasal keratinocytes': '1.5', 'Basal squamous epithelial cells': '0.7', 'Squamous epithelial cells': '0.5', 'Alveolar cells type 1': '-0.081', 'Alveolar cells type 2': '-0.506', 'Salivary duct cells': '0.9', 'Ductal cells': '0.437', 'Hepatocytes': '-0.191', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '0.087', 'Distal tubular cells': '6.1', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.299', 'Sertoli cells': '0.456', 'Granulosa cells': '1.4', 'Enteroendocrine cells': '29.5', 'Pancreatic endocrine cells': '34.0', 'Leydig cells': '0.326', 'Excitatory neurons': '58.6', 'Inhibitory neurons': '15.9', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.7', 'Bipolar cells': '6.1', 'Horizontal cells': '8.8', 'Astrocytes': '7.7', 'Oligodendrocyte precursor cells': '8.0', 'Oligodendrocytes': '4.5', 'Microglial cells': '5.4', 'Muller glia cells': '1.1', 'Schwann cells': '0.465', 'Spermatogonia': '0.191', 'Spermatocytes': '-0.179', 'Early spermatids': '-0.484', 'Late spermatids': '-0.421', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.4', 'Syncytiotrophoblasts': '0.6', 'Extravillous trophoblasts': '2.0', 'Endothelial cells': '1.1', 'Lymphatic endothelial cells': '0.6', 'Cardiomyocytes': '0.286', 'Skeletal myocytes': '-0.235', 'Smooth muscle cells': '1.8', 'Adipocytes': '0.8', 'Melanocytes': '-0.097', 'Fibroblasts': '1.4', 'Peritubular cells': '0.340', 'Endometrial stromal cells': '2.4', 'Ovarian stromal cells': '1.7', 'Undifferentiated cells': '1.7', 'T-cells': '4.5', 'B-cells': '0.6', 'Plasma cells': '0.8', 'Nk-cells': '4.0', 'Granulocytes': '2.8', 'Monocytes': '0.2', 'Macrophages': '1.7', 'Hofbauer cells': '0.6', 'Kupffer cells': '0.7', 'Dendritic cells': '0.0', 'Langerhans cells': '0.082', 'Erythroid cells': '0.119', 'Adipocytes (Subcutaneous)': '0.025', 'Adipocytes (Visceral)': '-0.338', 'Breast glandular cells (progenitors)': '0.337', 'Adipocytes (Breast)': '-0.437', 'Colon enterocytes': '-0.206', 'Colon enteroendocrine cells': '0.327', 'Enteric glia cells': '0.653', 'Mitotic cells (Colon)': '-0.246', 'Mitotic cells (Heart)': '0.404', 'Podocytes': '-0.193', 'Ascending Loop of Henle cells': '0.265', 'Intercalated cells': '-0.210', 'Cholangiocyte': '0.261', 'NK-cells (Liver)': '-0.014', 'Respiratory ciliated cells': '0.192', 'Mitotic cells (Lung)': '-0.079', 'NK-cells (Lung)': '0.422', 'B-cells (Lung)': '0.362', 'Alpha cells': '0.670', 'Beta cells': '0.760', 'Prostate glandular cells': '-0.275', 'Prostate basal glandular cells': '0.228', 'Urothelial cells': '0.482', 'Keratinocyte (other)': '-0.091', 'Keratinocyte (granular)': '-0.293', 'Hair cortex cells': '0.063', 'Inner root sheath cells': '0.051', 'Outer root sheath cells': '0.304', 'Sebaceous gland cells': '0.028', 'Eccrine sweat gland cells': '0.161', 'Adipocytes (Skin)': '-0.025', 'Mitotic cells (Skin)': '0.164', 'Parietal cells': '-0.732', 'Chief cells': '-0.520', 'Gastric mucous cells': '-0.482', 'Gastric enteroendocrine cells': '-0.210', 'Mitotic cells (Stomach)': '-0.152', 'Parafollicular cells': '0.080', 'Thyroid glandular cells': '-0.020', 'Mitotic cells (Thyroid)': '0.045', 'Adrenal cortex cells': '0.124', 'Adrenal medulla cells': '0.582', 'Mitotic cells (Adrenal gland)': '-0.020', 'Minor salivary glandular cells': '0.486', 'Minor salivary gland ductal cells': '0.263', 'Minor salivary gland basal cells': '-0.104', 'Mitotic cells (Minor salivary gland)': '-0.081', 'Adipocytes (Minor salivary gland)': '-0.018', 'Somatotropes': '0.509', 'Lactotropes': '0.500', 'Gonadotropes': '0.045', 'Corticotropes': '0.113', 'Thyrotropes': '0.069', 'Undifferentiated cells (Pituitary gland)': '-0.424', 'Mitotic cells (Spleen)': '-0.256', 'Platelets': '-0.217', 'Erythrocytes': '0.073', 'Hematopoietic stem cells': '-0.181', 'B-cells (Spleen)': '0.176', 'NK-cells (Spleen)': '0.204', 'Amygdala excitatory': '65.2', 'Cerebellar inhibitory': '3.2', 'Cge interneuron': '20.5', 'Deep-layer corticothalamic and 6b': '104.9', 'Deep-layer intratelencephalic': '114.1', 'Deep-layer near-projecting': '74.8', 'Eccentric medium spiny neuron': '18.8', 'Hippocampal ca1-3': '69.8', 'Hippocampal ca4': '60.1', 'Hippocampal dentate gyrus': '14.1', 'Lamp5-lhx6 and chandelier': '32.5', 'Lower rhombic lip': '15.4', 'Mammillary body': '4.6', 'Medium spiny neuron': '10.6', 'Mge interneuron': '29.6', 'Midbrain-derived inhibitory': '4.4', 'Miscellaneous': '86.4', 'Splatter': '16.1', 'Thalamic excitatory': '20.8', 'Upper rhombic lip': '28.8', 'Upper-layer intratelencephalic': '76.4', 'Astrocyte': '5.2', 'Bergmann glia': '4.8', 'Central nervous system macrophage': '4.8', 'Choroid plexus epithelial cell': '4.5', 'Committed oligodendrocyte precursor': '8.8', 'Ependymal cell': '4.1', 'Oligodendrocyte': '2.8', 'Oligodendrocyte precursor cell': '4.6', 'Endothelial cell': '3.6', 'Pericyte': '2.5', 'Vascular associated smooth muscle cell': '6.4', 'Fibroblast': '4.2', 'Leukocyte': '9.6', 'Basophil': '5.4', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '3.6', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.2', 'T-reg': '4.2', 'GdT-cell': '0.6', 'MAIT T-cell': '10.2', 'Memory CD4 T-cell': '0.1', 'Naive CD4 T-cell': '2.7', 'Memory CD8 T-cell': '0.1', 'Naive CD8 T-cell': '3.2', 'Memory B-cell': '0.1', 'Naive B-cell': '0.4', 'Plasmacytoid DC': '0.5', 'Myeloid DC': '1.5', 'NK-cell': '8.0', 'Total PBMC': '4.6', 'Vd2 gdTCR': '10.4', 'Memory CD4 T-cell Th1\\/Th17': '3.8', 'Memory CD4 T-cell Th17': '6.0', 'Memory CD4 T-cell Th2': '5.3', 'Non-Vd2 gdTCR': '12.5', 'Memory CD4 T-cell Th1': '5.1', 'Memory CD4 T-cell TFH': '4.1', 'Terminal effector memory CD4 T-cell': '6.2', 'Central memory CD8 T-cell': '4.7', 'Effector memory CD8 T-cell': '9.1', 'Terminal effector memory CD8 T-cell': '8.6', 'Non-switched memory B-cell': '3.1', 'Plasmablast': '0.9', 'Switched memory B-cell': '2.1', 'Exhausted memory B-cell': '0.5', 'Progenitor cell': '0.8', 'Memory T-reg': '13.7', 'Naive CD4 T-cell activated': '15.4', 'Naive CD8 T-cell activated': '26.0', 'Naive T-reg': '2.1'}
null
{'Adipose Tissue': 3.8184878737541528, 'Adrenal Gland': 4.1248422480620155, 'Bladder': 7.858714285714287, 'Blood': 4.233672981700753, 'Blood Vessel': 8.565213857677902, 'Brain': 72.06128531415594, 'Breast': 4.507673202614379, 'Cervix Uteri': 12.392, 'Colon': 12.918314762516047, 'Esophagus': 7.305368581314879, 'Fallopian Tube': 9.242222222222225, 'Heart': 1.2917862833914056, 'Kidney': 3.277966292134831, 'Liver': 1.582430088495575, 'Lung': 7.534835640138409, 'Muscle': 1.5308422166874225, 'Nerve': 5.43135056542811, 'Ovary': 7.245605555555556, 'Pancreas': 5.569709146341464, 'Pituitary': 119.94032862190812, 'Prostate': 9.398036734693877, 'Salivary Gland': 4.749679012345679, 'Skin': 5.793670702045329, 'Small Intestine': 6.784053475935829, 'Spleen': 4.69336929460581, 'Stomach': 6.5020077994428975, 'Testis': 11.76693351800554, 'Thyroid': 6.250679938744257, 'Uterus': 11.947077464788732, 'Vagina': 8.746269230769231}
[38.7, 39.64, 35.6, 37.72, 36.84, 33.09, 39.61, 33.17, 40.8, 37.22, 38.94, 36.15, 31.2, 34.39, 36.06, 33.43, 38.09, 42.58, 37.78, 37.92, 37.38, 38.75, 37.56, 38.45, 37.77, 39.04, 41.48, 39.52, 42.67, 40.01, 45.24, 40.63, 45.89, 42.49, 51.66, 56.27, 59.87, 58.29, 61.8, 67.6, 66.44, 77.0, 84.15, 80.25, 81.31, 80.93, 77.46, 81.44, 81.19, 83.14, 84.25, 86.73, 82.46, 83.13, 86.45, 85.63, 89.79, 88.2, 90.08, 90.71, 89.8, 92.18, 91.51, 92.6, 89.77, 93.05, 94.32, 92.24, 92.95, 92.42, 93.89, 93.15, 93.25, 94.71, 93.58, 94.28, 91.37, 93.75, 91.69, 91.71, 91.64, 89.96, 90.12, 86.16, 84.0, 82.27, 84.18, 84.53, 81.8, 81.92, 80.86, 80.4, 78.14, 78.72, 79.45, 80.08, 77.37, 80.76, 79.78, 76.81, 78.32, 78.97, 79.75, 76.57, 77.2, 78.96, 77.49, 74.62, 77.22, 78.98, 70.18, 67.31, 70.61, 57.3, 52.23, 51.12, 47.49, 41.16, 41.55, 33.33, 32.22, 37.04, 31.7, 33.25, 30.97, 30.54, 29.87, 33.58, 30.28, 24.57, 38.28, 26.8, 33.71, 31.22, 27.2, 33.42, 31.43, 29.19, 35.76, 30.56, 33.26, 30.28, 32.35, 32.05, 33.8, 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[52.31, 57.44, 62.0, 70.4, 71.67, 64.31, 68.12, 55.35, 53.66, 56.67, 51.43, 46.62, 42.48, 47.11, 44.98, 43.69, 41.0, 42.85, 38.32, 48.89, 42.04, 49.95, 52.09, 58.73, 64.79, 65.37, 76.72, 85.52, 86.83, 87.74, 91.22, 91.93, 92.87, 93.63, 95.39, 95.8, 96.02, 96.89, 97.81, 98.11, 97.93, 98.37, 98.5, 98.2, 98.51, 98.46, 98.28, 98.44, 98.59, 98.33, 98.17, 98.4, 98.27, 97.98, 97.68, 97.42, 96.8, 96.55, 95.7, 95.02, 94.73, 93.22, 92.74, 89.56, 83.72, 84.92, 86.12, 89.38, 92.03, 94.36, 94.44, 93.24, 95.19, 96.55, 95.77, 94.36, 96.71, 97.47, 95.51, 95.36, 96.94, 96.56, 94.57, 95.86, 97.5, 95.71, 94.19, 96.08, 95.97, 93.43, 94.08, 95.51, 94.3, 92.38, 93.56, 92.94, 90.87, 91.1, 90.08, 88.85, 88.33, 87.64, 83.78, 81.06, 78.27, 80.69, 65.56, 66.41, 69.14, 78.95, 79.13, 83.69, 84.81, 82.15, 84.73, 89.27, 86.62, 84.19, 89.72, 90.62, 87.67, 88.31, 93.06, 92.11, 88.77, 92.05, 94.28, 91.46, 91.38, 95.74, 94.25, 92.62, 95.32, 96.34, 93.99, 95.23, 96.41, 95.99, 95.14, 96.8, 97.04, 96.14, 96.44, 96.63, 95.91, 95.36, 95.29, 94.54, 94.32, 94.48, 93.52, 92.19, 92.17, 92.13, 88.89, 88.71, 86.66, 87.07, 88.32, 89.78, 92.93, 91.76, 93.59, 92.36, 93.66, 94.35, 92.79, 91.92, 92.45, 89.11, 86.94, 78.44, 82.65, 79.78, 84.56, 86.4, 86.52, 85.37, 82.97, 78.71, 80.69, 77.77, 74.97, 78.6, 83.78, 87.37, 87.58, 87.33, 88.12, 89.88, 90.43, 90.18, 90.37, 91.82, 92.81, 91.0, 91.98, 93.82, 93.03, 91.34, 92.24, 94.41, 92.35, 90.75, 92.91, 91.27, 89.41, 89.74, 89.97, 89.33, 84.36, 87.43, 84.35, 84.42, 84.44, 82.28, 78.82, 73.55, 73.9, 71.44, 66.39, 64.32, 66.33, 63.44, 57.96, 58.06, 58.36, 60.2, 60.05, 60.13, 62.26, 62.76, 58.33, 59.6, 66.06, 64.33, 64.73, 62.72, 61.66, 68.14, 68.53, 69.93, 75.69, 78.01, 75.6, 79.4, 83.74, 87.05, 87.33, 89.39, 90.08, 89.39, 91.65, 90.44, 91.18, 91.81, 92.87, 90.29, 90.78, 91.72, 91.47, 92.88, 92.9, 92.37, 93.56, 94.92, 94.76, 95.27, 95.46, 95.78, 95.44, 95.31, 95.9, 95.36, 94.69, 93.99, 93.64, 93.32, 91.76, 90.35, 89.82, 89.25, 87.77, 79.94, 77.45, 79.94, 68.09, 55.99]
[0.98, 0.9, 0.69, 0.65, 0.54, 0.78, 0.54, 0.68, 0.73, 0.59, 0.4, 0.79, 0.84, 0.6, 0.77, 0.68, 0.93, 0.69, 0.84, 0.77, 0.63, 0.54, 0.48, 0.57, 0.72, 0.5, 0.47, 0.6, 0.44, 0.09, 0.54, 0.55, 0.04, 0.42, 0.68, 0.35, 0.01, 0.61, 0.39, 0.0, 0.35, 0.44, 0.19, 0.01, 0.59, 0.41, 0.01, 0.32, 0.65, 0.12, 0.01, 0.49, 0.38, 0.0, 0.29, 0.7, 0.22, 0.03, 0.44, 0.46, 0.01, 0.06, 0.74, 0.38, 0.4, 0.74, 0.12, 0.54, 0.57, 0.65, 0.12, 0.23, 0.6, 0.28, 0.09, 0.48, 0.66, 0.15, 0.18, 0.35, 0.28, 0.0, 0.47, 0.58, 0.08, 0.01, 0.27, 0.52, 0.0, 0.29, 0.59, 0.25, 0.0, 0.52, 0.52, 0.05, 0.23, 0.55, 0.32, 0.06, 0.57, 0.72, 0.21, 0.39, 0.71, 0.62, 0.84, 0.64, 0.77, 0.26, 0.42, 0.15, 0.02, 0.32, 0.38, 0.05, 0.13, 0.35, 0.22, 0.04, 0.06, 0.42, 0.05, 0.01, 0.5, 0.42, 0.01, 0.23, 0.55, 0.04, 0.03, 0.4, 0.45, 0.01, 0.28, 0.52, 0.11, 0.0, 0.41, 0.51, 0.03, 0.2, 0.61, 0.39, 0.0, 0.08, 0.25, 0.29, 0.01, 0.29, 0.5, 0.14, 0.0, 0.53, 0.58, 0.2, 0.74, 0.28, 0.87, 0.07, 0.55, 0.48, 0.76, 0.48, 0.0, 0.23, 0.57, 0.04, 0.04, 0.71, 0.46, 0.48, 0.55, 0.46, 0.56, 0.34, 0.02, 0.34, 0.56, 0.92, 0.1, 0.68, 0.5, 0.85, 0.39, 0.72, 0.61, 0.1, 0.55, 0.62, 0.02, 0.1, 0.41, 0.07, 0.01, 0.62, 0.25, 0.01, 0.02, 0.41, 0.14, 0.02, 0.4, 0.46, 0.03, 0.29, 0.44, 0.11, 0.24, 0.56, 0.38, 0.05, 0.55, 0.57, 0.08, 0.25, 0.57, 0.36, 0.02, 0.52, 0.7, 0.07, 0.38, 0.84, 0.57, 0.06, 0.45, 0.63, 0.16, 0.38, 0.61, 0.53, 0.12, 0.66, 0.59, 0.44, 0.56, 0.62, 0.3, 0.42, 0.59, 0.39, 0.66, 0.6, 0.69, 0.62, 0.46, 0.44, 0.4, 0.52, 0.57, 0.68, 0.48, 0.5, 0.58, 0.6, 0.65, 0.57, 0.29, 0.52, 0.52, 0.5, 0.73, 0.67, 0.66, 0.57, 0.64, 0.6, 0.54, 0.48, 0.53, 0.57, 0.54, 0.55, 0.59, 0.44, 0.6, 0.53, 0.61, 0.56, 0.59, 0.53, 0.47, 0.42, 0.61, 0.8, 0.83, 0.78]
RING finger
Component of the RNF20/40 E3 ubiquitin-protein ligase complex
RNF20/40
null
H2B, RB1, WAC
H2B
mono
null
UBE2E1, UBE2B, UBE2A
null
null
72.436484
0.620949
84.767604
0.412986
2,434
O75150
Q16778
16307923
UbiNet, UbiBrowser, 31181401
RNF40
MSGPGNKRAAGDGGSGPPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSSAPEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPPLSEPALAFVVALGASSSEEVELELQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLATKNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAHSTPNLGHPEDSGVSAPAPGKEEGGPGPVSTPDNRKEMAPVPGTTTTTTSVKKEELVPSEEDFQGITPGAQGPSSRGREPEARPKRELREREGPSLGPPPVASALSRADREKAKVEETKRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS
Homo sapiens
Nucleus
Low tissue specificity
{'Ciliated cells': '17.9', 'Basal respiratory cells': '10.3', 'Club cells': '16.3', 'Ionocytes': '9.6', 'Mucus glandular cells': '14.5', 'Serous glandular cells': '14.6', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '22.1', 'Paneth cells': '26.2', 'Distal enterocytes': '30.4', 'Intestinal goblet cells': '25.6', 'Exocrine glandular cells': '-0.664', 'Basal prostatic cells': '26.0', 'Prostatic glandular cells': '18.7', 'Breast glandular cells': '0.601', 'Breast myoepithelial cells': '0.577', 'Glandular and luminal cells': '27.3', 'Secretory cells': '16.8', 'Basal keratinocytes': '19.2', 'Suprabasal keratinocytes': '21.2', 'Basal squamous epithelial cells': '18.0', 'Squamous epithelial cells': '20.6', 'Alveolar cells type 1': '0.193', 'Alveolar cells type 2': '0.263', 'Salivary duct cells': '16.0', 'Ductal cells': '0.618', 'Hepatocytes': '0.565', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.208', 'Distal tubular cells': '64.5', 'Collecting duct cells': '25.3', 'Mesothelial cells': '0.426', 'Sertoli cells': '0.081', 'Granulosa cells': '13.8', 'Enteroendocrine cells': '29.5', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '-0.048', 'Excitatory neurons': '10.0', 'Inhibitory neurons': '10.7', 'Cone photoreceptor cells': '17.0', 'Rod photoreceptor cells': '9.5', 'Bipolar cells': '11.7', 'Horizontal cells': '16.4', 'Astrocytes': '17.3', 'Oligodendrocyte precursor cells': '12.3', 'Oligodendrocytes': '8.0', 'Microglial cells': '4.5', 'Muller glia cells': '16.6', 'Schwann cells': '0.053', 'Spermatogonia': '0.256', 'Spermatocytes': '0.525', 'Early spermatids': '0.441', 'Late spermatids': '0.100', 'Oocytes': '14.0', 'Cytotrophoblasts': '16.2', 'Syncytiotrophoblasts': '20.6', 'Extravillous trophoblasts': '16.0', 'Endothelial cells': '16.3', 'Lymphatic endothelial cells': '13.5', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '-0.278', 'Smooth muscle cells': '14.8', 'Adipocytes': '12.9', 'Melanocytes': '0.259', 'Fibroblasts': '14.8', 'Peritubular cells': '-0.022', 'Endometrial stromal cells': '19.9', 'Ovarian stromal cells': '14.0', 'Undifferentiated cells': '22.9', 'T-cells': '16.4', 'B-cells': '17.4', 'Plasma cells': '20.0', 'Nk-cells': '16.3', 'Granulocytes': '8.8', 'Monocytes': '17.6', 'Macrophages': '18.8', 'Hofbauer cells': '20.7', 'Kupffer cells': '20.4', 'Dendritic cells': '18.3', 'Langerhans cells': '0.357', 'Erythroid cells': '-0.165', 'Adipocytes (Subcutaneous)': '-0.241', 'Adipocytes (Visceral)': '-0.070', 'Breast glandular cells (progenitors)': '0.525', 'Adipocytes (Breast)': '-0.522', 'Colon enterocytes': '0.060', 'Colon enteroendocrine cells': '0.199', 'Enteric glia cells': '-0.333', 'Mitotic cells (Colon)': '0.017', 'Mitotic cells (Heart)': '0.487', 'Podocytes': '-0.142', 'Ascending Loop of Henle cells': '0.480', 'Intercalated cells': '0.015', 'Cholangiocyte': '0.343', 'NK-cells (Liver)': '-0.361', 'Respiratory ciliated cells': '-0.021', 'Mitotic cells (Lung)': '0.064', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.177', 'Alpha cells': '0.421', 'Beta cells': '0.208', 'Prostate glandular cells': '0.231', 'Prostate basal glandular cells': '0.379', 'Urothelial cells': '0.144', 'Keratinocyte (other)': '0.412', 'Keratinocyte (granular)': '0.060', 'Hair cortex cells': '-0.020', 'Inner root sheath cells': '-0.005', 'Outer root sheath cells': '0.092', 'Sebaceous gland cells': '0.034', 'Eccrine sweat gland cells': '-0.115', 'Adipocytes (Skin)': '-0.134', 'Mitotic cells (Skin)': '0.294', 'Parietal cells': '-0.521', 'Chief cells': '-0.459', 'Gastric mucous cells': '-0.223', 'Gastric enteroendocrine cells': '-0.355', 'Mitotic cells (Stomach)': '0.171', 'Parafollicular cells': '0.135', 'Thyroid glandular cells': '0.508', 'Mitotic cells (Thyroid)': '-0.079', 'Adrenal cortex cells': '0.597', 'Adrenal medulla cells': '0.033', 'Mitotic cells (Adrenal gland)': '0.445', 'Minor salivary glandular cells': '0.475', 'Minor salivary gland ductal cells': '0.114', 'Minor salivary gland basal cells': '0.410', 'Mitotic cells (Minor salivary gland)': '0.369', 'Adipocytes (Minor salivary gland)': '0.171', 'Somatotropes': '-0.052', 'Lactotropes': '-0.082', 'Gonadotropes': '0.059', 'Corticotropes': '-0.087', 'Thyrotropes': '0.020', 'Undifferentiated cells (Pituitary gland)': '0.313', 'Mitotic cells (Spleen)': '-0.010', 'Platelets': '-0.035', 'Erythrocytes': '-0.068', 'Hematopoietic stem cells': '-0.175', 'B-cells (Spleen)': '0.282', 'NK-cells (Spleen)': '0.212', 'Amygdala excitatory': '15.9', 'Cerebellar inhibitory': '16.9', 'Cge interneuron': '17.8', 'Deep-layer corticothalamic and 6b': '15.2', 'Deep-layer intratelencephalic': '15.1', 'Deep-layer near-projecting': '16.1', 'Eccentric medium spiny neuron': '16.9', 'Hippocampal ca1-3': '18.4', 'Hippocampal ca4': '16.8', 'Hippocampal dentate gyrus': '13.9', 'Lamp5-lhx6 and chandelier': '17.2', 'Lower rhombic lip': '10.6', 'Mammillary body': '12.5', 'Medium spiny neuron': '15.9', 'Mge interneuron': '17.6', 'Midbrain-derived inhibitory': '18.7', 'Miscellaneous': '16.2', 'Splatter': '14.0', 'Thalamic excitatory': '16.0', 'Upper rhombic lip': '16.0', 'Upper-layer intratelencephalic': '15.1', 'Astrocyte': '22.9', 'Bergmann glia': '21.5', 'Central nervous system macrophage': '17.7', 'Choroid plexus epithelial cell': '12.2', 'Committed oligodendrocyte precursor': '19.3', 'Ependymal cell': '19.0', 'Oligodendrocyte': '11.2', 'Oligodendrocyte precursor cell': '17.7', 'Endothelial cell': '16.8', 'Pericyte': '19.8', 'Vascular associated smooth muscle cell': '17.8', 'Fibroblast': '17.6', 'Leukocyte': '16.3', 'Basophil': '88.5', 'Eosinophil': '17.2', 'Neutrophil': '140.5', 'Classical monocyte': '33.0', 'Non-classical monocyte': '24.4', 'Intermediate monocyte': '86.7', 'T-reg': '52.8', 'GdT-cell': '13.2', 'MAIT T-cell': '79.6', 'Memory CD4 T-cell': '7.2', 'Naive CD4 T-cell': '18.0', 'Memory CD8 T-cell': '10.0', 'Naive CD8 T-cell': '24.5', 'Memory B-cell': '8.1', 'Naive B-cell': '16.9', 'Plasmacytoid DC': '68.0', 'Myeloid DC': '69.2', 'NK-cell': '38.9', 'Total PBMC': '59.4', 'Vd2 gdTCR': '70.5', 'Memory CD4 T-cell Th1\\/Th17': '19.1', 'Memory CD4 T-cell Th17': '21.5', 'Memory CD4 T-cell Th2': '22.8', 'Non-Vd2 gdTCR': '78.7', 'Memory CD4 T-cell Th1': '28.1', 'Memory CD4 T-cell TFH': '33.1', 'Terminal effector memory CD4 T-cell': '69.4', 'Central memory CD8 T-cell': '62.9', 'Effector memory CD8 T-cell': '83.9', 'Terminal effector memory CD8 T-cell': '74.8', 'Non-switched memory B-cell': '49.5', 'Plasmablast': '59.3', 'Switched memory B-cell': '59.0', 'Exhausted memory B-cell': '63.9', 'Progenitor cell': '78.3', 'Naive CD4 T-cell activated': '13.9', 'Naive CD8 T-cell activated': '24.6', 'Memory T-reg': '32.7', 'Naive T-reg': '25.3'}
8GUI, 8GUJ, 8IEJ
{'Adipose Tissue': 35.89617940199336, 'Adrenal Gland': 35.863279069767444, 'Bladder': 38.30285714285714, 'Blood': 35.896346609257265, 'Blood Vessel': 42.135866666666665, 'Brain': 24.48113580620742, 'Breast': 40.03095860566449, 'Cervix Uteri': 52.26894736842105, 'Colon': 31.54429396662388, 'Esophagus': 34.059725259515574, 'Fallopian Tube': 48.76555555555555, 'Heart': 13.445284552845528, 'Kidney': 20.505415730337077, 'Liver': 12.66583628318584, 'Lung': 40.21266435986159, 'Muscle': 14.072226650062266, 'Nerve': 48.54226171243942, 'Ovary': 54.63477777777778, 'Pancreas': 14.481707317073171, 'Pituitary': 38.49226148409894, 'Prostate': 39.41742857142857, 'Salivary Gland': 35.94524691358025, 'Skin': 48.537831951354335, 'Small Intestine': 33.137647058823525, 'Spleen': 32.4444398340249, 'Stomach': 27.62590529247911, 'Testis': 73.01493074792243, 'Thyroid': 54.08897396630934, 'Uterus': 54.04042253521126, 'Vagina': 42.33967948717949}
H2BC21
MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
Homo sapiens
Nucleus, Chromosome
Low tissue specificity
{'Ciliated cells': '18.0', 'Basal respiratory cells': '16.8', 'Club cells': '25.7', 'Ionocytes': '27.2', 'Mucus glandular cells': '5.0', 'Serous glandular cells': '7.1', 'Gastric mucus-secreting cells': '13.0', 'Proximal enterocytes': '22.1', 'Paneth cells': '21.6', 'Distal enterocytes': '12.7', 'Intestinal goblet cells': '22.2', 'Exocrine glandular cells': '-0.127', 'Basal prostatic cells': '8.7', 'Prostatic glandular cells': '59.8', 'Breast glandular cells': '0.539', 'Breast myoepithelial cells': '0.547', 'Glandular and luminal cells': '15.7', 'Secretory cells': '11.2', 'Basal keratinocytes': '5.5', 'Suprabasal keratinocytes': '14.5', 'Basal squamous epithelial cells': '15.1', 'Squamous epithelial cells': '21.4', 'Alveolar cells type 1': '0.038', 'Alveolar cells type 2': '-0.484', 'Salivary duct cells': '4.0', 'Ductal cells': '0.116', 'Hepatocytes': '0.030', 'Cholangiocytes': '7.6', 'Proximal tubular cells': '-0.010', 'Distal tubular cells': '24.6', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.187', 'Sertoli cells': '0.479', 'Granulosa cells': '4.8', 'Enteroendocrine cells': '43.1', 'Pancreatic endocrine cells': '10.2', 'Leydig cells': '0.440', 'Excitatory neurons': '0.4', 'Inhibitory neurons': '0.8', 'Cone photoreceptor cells': '25.5', 'Rod photoreceptor cells': '36.4', 'Bipolar cells': '58.6', 'Horizontal cells': '21.4', 'Astrocytes': '9.9', 'Oligodendrocyte precursor cells': '0.5', 'Oligodendrocytes': '6.3', 'Microglial cells': '2.7', 'Muller glia cells': '13.9', 'Schwann cells': '0.012', 'Spermatogonia': '0.109', 'Spermatocytes': '-0.198', 'Early spermatids': '-0.475', 'Late spermatids': '-0.467', 'Oocytes': '2.9', 'Cytotrophoblasts': '24.2', 'Syncytiotrophoblasts': '233.7', 'Extravillous trophoblasts': '23.4', 'Endothelial cells': '6.1', 'Lymphatic endothelial cells': '0.4', 'Cardiomyocytes': '0.709', 'Skeletal myocytes': '-0.125', 'Smooth muscle cells': '8.6', 'Adipocytes': '6.6', 'Melanocytes': '0.158', 'Fibroblasts': '7.1', 'Peritubular cells': '0.366', 'Endometrial stromal cells': '8.8', 'Ovarian stromal cells': '17.9', 'Undifferentiated cells': '9.1', 'T-cells': '10.3', 'B-cells': '6.1', 'Plasma cells': '13.2', 'Nk-cells': '5.6', 'Granulocytes': '1.4', 'Monocytes': '12.4', 'Macrophages': '12.6', 'Hofbauer cells': '24.9', 'Kupffer cells': '10.7', 'Dendritic cells': '20.0', 'Langerhans cells': '0.069', 'Erythroid cells': '0.230', 'Adipocytes (Subcutaneous)': '-0.152', 'Adipocytes (Visceral)': '-0.355', 'Breast glandular cells (progenitors)': '0.464', 'Adipocytes (Breast)': '-0.631', 'Colon enterocytes': '-0.006', 'Colon enteroendocrine cells': '0.084', 'Enteric glia cells': '-0.133', 'Mitotic cells (Colon)': '0.104', 'Mitotic cells (Heart)': '0.352', 'Podocytes': '0.069', 'Ascending Loop of Henle cells': '0.201', 'Intercalated cells': '0.060', 'Cholangiocyte': '0.215', 'NK-cells (Liver)': '0.023', 'Respiratory ciliated cells': '0.162', 'Mitotic cells (Lung)': '-0.118', 'NK-cells (Lung)': '0.418', 'B-cells (Lung)': '0.269', 'Alpha cells': '0.207', 'Beta cells': '0.139', 'Prostate glandular cells': '0.430', 'Prostate basal glandular cells': '0.300', 'Urothelial cells': '0.306', 'Keratinocyte (other)': '0.267', 'Keratinocyte (granular)': '-0.340', 'Hair cortex cells': '0.053', 'Inner root sheath cells': '0.069', 'Outer root sheath cells': '0.289', 'Sebaceous gland cells': '-0.038', 'Eccrine sweat gland cells': '-0.013', 'Adipocytes (Skin)': '-0.306', 'Mitotic cells (Skin)': '0.257', 'Parietal cells': '-0.415', 'Chief cells': '-0.390', 'Gastric mucous cells': '-0.391', 'Gastric enteroendocrine cells': '-0.238', 'Mitotic cells (Stomach)': '-0.136', 'Parafollicular cells': '0.017', 'Thyroid glandular cells': '0.122', 'Mitotic cells (Thyroid)': '0.130', 'Adrenal cortex cells': '0.296', 'Adrenal medulla cells': '0.001', 'Mitotic cells (Adrenal gland)': '-0.052', 'Minor salivary glandular cells': '-0.108', 'Minor salivary gland ductal cells': '-0.097', 'Minor salivary gland basal cells': '0.119', 'Mitotic cells (Minor salivary gland)': '0.199', 'Adipocytes (Minor salivary gland)': '-0.003', 'Somatotropes': '0.053', 'Lactotropes': '0.131', 'Gonadotropes': '0.168', 'Corticotropes': '0.015', 'Thyrotropes': '0.213', 'Undifferentiated cells (Pituitary gland)': '0.140', 'Mitotic cells (Spleen)': '0.069', 'Platelets': '-0.122', 'Erythrocytes': '0.184', 'Hematopoietic stem cells': '-0.107', 'B-cells (Spleen)': '0.009', 'NK-cells (Spleen)': '0.204', 'Amygdala excitatory': '0.4', 'Cerebellar inhibitory': '2.9', 'Cge interneuron': '1.7', 'Deep-layer corticothalamic and 6b': '0.4', 'Deep-layer intratelencephalic': '0.6', 'Deep-layer near-projecting': '0.1', 'Eccentric medium spiny neuron': '0.9', 'Hippocampal ca1-3': '1.2', 'Hippocampal ca4': '1.5', 'Hippocampal dentate gyrus': '1.3', 'Lamp5-lhx6 and chandelier': '2.3', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.6', 'Medium spiny neuron': '0.7', 'Mge interneuron': '1.3', 'Midbrain-derived inhibitory': '2.6', 'Miscellaneous': '0.5', 'Splatter': '1.0', 'Thalamic excitatory': '0.6', 'Upper rhombic lip': '3.1', 'Upper-layer intratelencephalic': '0.4', 'Astrocyte': '14.0', 'Bergmann glia': '1.9', 'Central nervous system macrophage': '34.3', 'Choroid plexus epithelial cell': '4.6', 'Committed oligodendrocyte precursor': '6.3', 'Ependymal cell': '11.0', 'Oligodendrocyte': '7.8', 'Oligodendrocyte precursor cell': '1.6', 'Endothelial cell': '8.4', 'Pericyte': '0.8', 'Vascular associated smooth muscle cell': '4.1', 'Fibroblast': '1.2', 'Leukocyte': '10.8', 'Basophil': '48.1', 'Eosinophil': '8.2', 'Neutrophil': '301.2', 'Classical monocyte': '48.3', 'Non-classical monocyte': '49.1', 'Intermediate monocyte': '69.6', 'T-reg': '8.0', 'GdT-cell': '1.4', 'MAIT T-cell': '8.5', 'Memory CD4 T-cell': '1.9', 'Naive CD4 T-cell': '39.9', 'Memory CD8 T-cell': '2.2', 'Naive CD8 T-cell': '34.7', 'Memory B-cell': '1.6', 'Naive B-cell': '21.8', 'Plasmacytoid DC': '27.1', 'Myeloid DC': '22.0', 'NK-cell': '29.4', 'Total PBMC': '60.3', 'Vd2 gdTCR': '5.8', 'Memory CD4 T-cell Th1\\/Th17': '45.2', 'Memory CD4 T-cell Th17': '42.1', 'Memory CD4 T-cell Th2': '43.8', 'Non-Vd2 gdTCR': '10.3', 'Memory CD4 T-cell Th1': '38.9', 'Memory CD4 T-cell TFH': '26.1', 'Terminal effector memory CD4 T-cell': '5.4', 'Central memory CD8 T-cell': '5.8', 'Effector memory CD8 T-cell': '6.8', 'Terminal effector memory CD8 T-cell': '4.6', 'Non-switched memory B-cell': '11.3', 'Plasmablast': '6.2', 'Switched memory B-cell': '4.6', 'Exhausted memory B-cell': '13.0', 'Progenitor cell': '121.2', 'Memory T-reg': '33.1', 'Naive CD4 T-cell activated': '8.1', 'Naive CD8 T-cell activated': '6.9', 'Naive T-reg': '35.6'}
4NFT, 6A7U, 6KBB, 6M4D, 6M4G, 6M4H, 7BXT, 7EA8, 7U0G, 7U0I, 7U0J, 8DK5, 8EVG, 8EVH, 8EVI, 8EVJ, 8H1T, 8SPS, 8SPU, 8SYP, 8UQ8, 8UQ9, 8UQA, 8UQB, 8UQC, 8UQD, 8UQE, 8YJF
{}
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[61.74, 74.45, 71.22, 74.93, 74.98, 75.29, 78.65, 79.02, 75.48, 78.22, 79.33, 78.37, 78.68, 71.32, 75.39, 76.83, 78.07, 74.62, 77.91, 81.26, 75.92, 76.06, 73.98, 64.66, 69.2, 64.11, 58.88, 56.37, 57.75, 55.82, 59.58, 56.27, 55.84, 61.91, 69.34, 76.0, 90.0, 93.4, 92.58, 93.08, 93.96, 95.81, 95.58, 95.25, 95.77, 97.29, 97.68, 96.54, 97.68, 97.47, 97.49, 97.5, 97.03, 96.42, 97.29, 97.36, 95.49, 97.14, 97.62, 95.99, 95.67, 97.36, 97.42, 95.28, 96.3, 96.84, 96.44, 95.84, 96.76, 96.07, 96.34, 97.11, 97.75, 97.64, 97.69, 97.93, 98.01, 98.12, 97.91, 97.91, 97.9, 97.65, 97.26, 97.0, 96.55, 96.91, 96.61, 96.04, 97.19, 96.82, 94.01, 91.73, 92.84, 95.19, 95.97, 94.88, 96.22, 97.34, 97.23, 96.03, 96.89, 96.8, 95.58, 95.89, 95.4, 95.68, 95.62, 95.71, 95.23, 95.71, 95.1, 94.29, 94.58, 93.67, 92.46, 91.42, 92.01, 90.29, 89.99, 90.84, 92.69, 90.35, 92.98, 93.46, 88.16, 64.87]
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RING finger
Component of the RNF20/40 E3 ubiquitin-protein ligase complex
RNF20/40
null
H2B, RB1, WAC
H2B
mono
null
UBE2E1, UBE2B, UBE2A
null
null
72.436484
0.620949
88.224603
0.605714
2,841
O75150
Q96A08
16307923, E3Net
UbiNet, UbiBrowser, 31181401
RNF40
MSGPGNKRAAGDGGSGPPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSSAPEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPPLSEPALAFVVALGASSSEEVELELQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLATKNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAHSTPNLGHPEDSGVSAPAPGKEEGGPGPVSTPDNRKEMAPVPGTTTTTTSVKKEELVPSEEDFQGITPGAQGPSSRGREPEARPKRELREREGPSLGPPPVASALSRADREKAKVEETKRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS
Homo sapiens
Nucleus
Low tissue specificity
{'Ciliated cells': '17.9', 'Basal respiratory cells': '10.3', 'Club cells': '16.3', 'Ionocytes': '9.6', 'Mucus glandular cells': '14.5', 'Serous glandular cells': '14.6', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '22.1', 'Paneth cells': '26.2', 'Distal enterocytes': '30.4', 'Intestinal goblet cells': '25.6', 'Exocrine glandular cells': '-0.664', 'Basal prostatic cells': '26.0', 'Prostatic glandular cells': '18.7', 'Breast glandular cells': '0.601', 'Breast myoepithelial cells': '0.577', 'Glandular and luminal cells': '27.3', 'Secretory cells': '16.8', 'Basal keratinocytes': '19.2', 'Suprabasal keratinocytes': '21.2', 'Basal squamous epithelial cells': '18.0', 'Squamous epithelial cells': '20.6', 'Alveolar cells type 1': '0.193', 'Alveolar cells type 2': '0.263', 'Salivary duct cells': '16.0', 'Ductal cells': '0.618', 'Hepatocytes': '0.565', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.208', 'Distal tubular cells': '64.5', 'Collecting duct cells': '25.3', 'Mesothelial cells': '0.426', 'Sertoli cells': '0.081', 'Granulosa cells': '13.8', 'Enteroendocrine cells': '29.5', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '-0.048', 'Excitatory neurons': '10.0', 'Inhibitory neurons': '10.7', 'Cone photoreceptor cells': '17.0', 'Rod photoreceptor cells': '9.5', 'Bipolar cells': '11.7', 'Horizontal cells': '16.4', 'Astrocytes': '17.3', 'Oligodendrocyte precursor cells': '12.3', 'Oligodendrocytes': '8.0', 'Microglial cells': '4.5', 'Muller glia cells': '16.6', 'Schwann cells': '0.053', 'Spermatogonia': '0.256', 'Spermatocytes': '0.525', 'Early spermatids': '0.441', 'Late spermatids': '0.100', 'Oocytes': '14.0', 'Cytotrophoblasts': '16.2', 'Syncytiotrophoblasts': '20.6', 'Extravillous trophoblasts': '16.0', 'Endothelial cells': '16.3', 'Lymphatic endothelial cells': '13.5', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '-0.278', 'Smooth muscle cells': '14.8', 'Adipocytes': '12.9', 'Melanocytes': '0.259', 'Fibroblasts': '14.8', 'Peritubular cells': '-0.022', 'Endometrial stromal cells': '19.9', 'Ovarian stromal cells': '14.0', 'Undifferentiated cells': '22.9', 'T-cells': '16.4', 'B-cells': '17.4', 'Plasma cells': '20.0', 'Nk-cells': '16.3', 'Granulocytes': '8.8', 'Monocytes': '17.6', 'Macrophages': '18.8', 'Hofbauer cells': '20.7', 'Kupffer cells': '20.4', 'Dendritic cells': '18.3', 'Langerhans cells': '0.357', 'Erythroid cells': '-0.165', 'Adipocytes (Subcutaneous)': '-0.241', 'Adipocytes (Visceral)': '-0.070', 'Breast glandular cells (progenitors)': '0.525', 'Adipocytes (Breast)': '-0.522', 'Colon enterocytes': '0.060', 'Colon enteroendocrine cells': '0.199', 'Enteric glia cells': '-0.333', 'Mitotic cells (Colon)': '0.017', 'Mitotic cells (Heart)': '0.487', 'Podocytes': '-0.142', 'Ascending Loop of Henle cells': '0.480', 'Intercalated cells': '0.015', 'Cholangiocyte': '0.343', 'NK-cells (Liver)': '-0.361', 'Respiratory ciliated cells': '-0.021', 'Mitotic cells (Lung)': '0.064', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.177', 'Alpha cells': '0.421', 'Beta cells': '0.208', 'Prostate glandular cells': '0.231', 'Prostate basal glandular cells': '0.379', 'Urothelial cells': '0.144', 'Keratinocyte (other)': '0.412', 'Keratinocyte (granular)': '0.060', 'Hair cortex cells': '-0.020', 'Inner root sheath cells': '-0.005', 'Outer root sheath cells': '0.092', 'Sebaceous gland cells': '0.034', 'Eccrine sweat gland cells': '-0.115', 'Adipocytes (Skin)': '-0.134', 'Mitotic cells (Skin)': '0.294', 'Parietal cells': '-0.521', 'Chief cells': '-0.459', 'Gastric mucous cells': '-0.223', 'Gastric enteroendocrine cells': '-0.355', 'Mitotic cells (Stomach)': '0.171', 'Parafollicular cells': '0.135', 'Thyroid glandular cells': '0.508', 'Mitotic cells (Thyroid)': '-0.079', 'Adrenal cortex cells': '0.597', 'Adrenal medulla cells': '0.033', 'Mitotic cells (Adrenal gland)': '0.445', 'Minor salivary glandular cells': '0.475', 'Minor salivary gland ductal cells': '0.114', 'Minor salivary gland basal cells': '0.410', 'Mitotic cells (Minor salivary gland)': '0.369', 'Adipocytes (Minor salivary gland)': '0.171', 'Somatotropes': '-0.052', 'Lactotropes': '-0.082', 'Gonadotropes': '0.059', 'Corticotropes': '-0.087', 'Thyrotropes': '0.020', 'Undifferentiated cells (Pituitary gland)': '0.313', 'Mitotic cells (Spleen)': '-0.010', 'Platelets': '-0.035', 'Erythrocytes': '-0.068', 'Hematopoietic stem cells': '-0.175', 'B-cells (Spleen)': '0.282', 'NK-cells (Spleen)': '0.212', 'Amygdala excitatory': '15.9', 'Cerebellar inhibitory': '16.9', 'Cge interneuron': '17.8', 'Deep-layer corticothalamic and 6b': '15.2', 'Deep-layer intratelencephalic': '15.1', 'Deep-layer near-projecting': '16.1', 'Eccentric medium spiny neuron': '16.9', 'Hippocampal ca1-3': '18.4', 'Hippocampal ca4': '16.8', 'Hippocampal dentate gyrus': '13.9', 'Lamp5-lhx6 and chandelier': '17.2', 'Lower rhombic lip': '10.6', 'Mammillary body': '12.5', 'Medium spiny neuron': '15.9', 'Mge interneuron': '17.6', 'Midbrain-derived inhibitory': '18.7', 'Miscellaneous': '16.2', 'Splatter': '14.0', 'Thalamic excitatory': '16.0', 'Upper rhombic lip': '16.0', 'Upper-layer intratelencephalic': '15.1', 'Astrocyte': '22.9', 'Bergmann glia': '21.5', 'Central nervous system macrophage': '17.7', 'Choroid plexus epithelial cell': '12.2', 'Committed oligodendrocyte precursor': '19.3', 'Ependymal cell': '19.0', 'Oligodendrocyte': '11.2', 'Oligodendrocyte precursor cell': '17.7', 'Endothelial cell': '16.8', 'Pericyte': '19.8', 'Vascular associated smooth muscle cell': '17.8', 'Fibroblast': '17.6', 'Leukocyte': '16.3', 'Basophil': '88.5', 'Eosinophil': '17.2', 'Neutrophil': '140.5', 'Classical monocyte': '33.0', 'Non-classical monocyte': '24.4', 'Intermediate monocyte': '86.7', 'T-reg': '52.8', 'GdT-cell': '13.2', 'MAIT T-cell': '79.6', 'Memory CD4 T-cell': '7.2', 'Naive CD4 T-cell': '18.0', 'Memory CD8 T-cell': '10.0', 'Naive CD8 T-cell': '24.5', 'Memory B-cell': '8.1', 'Naive B-cell': '16.9', 'Plasmacytoid DC': '68.0', 'Myeloid DC': '69.2', 'NK-cell': '38.9', 'Total PBMC': '59.4', 'Vd2 gdTCR': '70.5', 'Memory CD4 T-cell Th1\\/Th17': '19.1', 'Memory CD4 T-cell Th17': '21.5', 'Memory CD4 T-cell Th2': '22.8', 'Non-Vd2 gdTCR': '78.7', 'Memory CD4 T-cell Th1': '28.1', 'Memory CD4 T-cell TFH': '33.1', 'Terminal effector memory CD4 T-cell': '69.4', 'Central memory CD8 T-cell': '62.9', 'Effector memory CD8 T-cell': '83.9', 'Terminal effector memory CD8 T-cell': '74.8', 'Non-switched memory B-cell': '49.5', 'Plasmablast': '59.3', 'Switched memory B-cell': '59.0', 'Exhausted memory B-cell': '63.9', 'Progenitor cell': '78.3', 'Naive CD4 T-cell activated': '13.9', 'Naive CD8 T-cell activated': '24.6', 'Memory T-reg': '32.7', 'Naive T-reg': '25.3'}
8GUI, 8GUJ, 8IEJ
{'Adipose Tissue': 35.89617940199336, 'Adrenal Gland': 35.863279069767444, 'Bladder': 38.30285714285714, 'Blood': 35.896346609257265, 'Blood Vessel': 42.135866666666665, 'Brain': 24.48113580620742, 'Breast': 40.03095860566449, 'Cervix Uteri': 52.26894736842105, 'Colon': 31.54429396662388, 'Esophagus': 34.059725259515574, 'Fallopian Tube': 48.76555555555555, 'Heart': 13.445284552845528, 'Kidney': 20.505415730337077, 'Liver': 12.66583628318584, 'Lung': 40.21266435986159, 'Muscle': 14.072226650062266, 'Nerve': 48.54226171243942, 'Ovary': 54.63477777777778, 'Pancreas': 14.481707317073171, 'Pituitary': 38.49226148409894, 'Prostate': 39.41742857142857, 'Salivary Gland': 35.94524691358025, 'Skin': 48.537831951354335, 'Small Intestine': 33.137647058823525, 'Spleen': 32.4444398340249, 'Stomach': 27.62590529247911, 'Testis': 73.01493074792243, 'Thyroid': 54.08897396630934, 'Uterus': 54.04042253521126, 'Vagina': 42.33967948717949}
H2BC1
MPEVSSKGATISKKGFKKAVVKTQKKEGKKRKRTRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIASEASRLAHYSKRSTISSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
Homo sapiens
Nucleus, Chromosome
Tissue enriched (testis)
{'Ciliated cells': '0.0', 'Basal respiratory cells': '0.0', 'Club cells': '0.0', 'Ionocytes': '0.0', 'Mucus glandular cells': '0.0', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '0.021', 'Basal prostatic cells': '0.0', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '0.006', 'Breast myoepithelial cells': '-0.153', 'Glandular and luminal cells': '0.0', 'Secretory cells': '0.0', 'Basal keratinocytes': '0.0', 'Suprabasal keratinocytes': '0.0', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '-0.059', 'Alveolar cells type 2': '0.040', 'Salivary duct cells': '0.0', 'Ductal cells': '0.059', 'Hepatocytes': '0.324', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.555', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.053', 'Sertoli cells': '-0.177', 'Granulosa cells': '0.0', 'Enteroendocrine cells': '0.0', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '-0.258', 'Excitatory neurons': '0.0', 'Inhibitory neurons': '0.0', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '0.0', 'Bipolar cells': '0.0', 'Horizontal cells': '0.0', 'Astrocytes': '0.0', 'Oligodendrocyte precursor cells': '0.0', 'Oligodendrocytes': '0.0', 'Microglial cells': '0.0', 'Muller glia cells': '0.0', 'Schwann cells': '-0.049', 'Spermatogonia': '-0.192', 'Spermatocytes': '0.024', 'Early spermatids': '0.254', 'Late spermatids': '0.270', 'Oocytes': '2.9', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.0', 'Extravillous trophoblasts': '0.0', 'Endothelial cells': '0.1', 'Lymphatic endothelial cells': '0.0', 'Cardiomyocytes': '-0.038', 'Skeletal myocytes': '-0.031', 'Smooth muscle cells': '0.0', 'Adipocytes': '0.0', 'Melanocytes': '0.071', 'Fibroblasts': '0.0', 'Peritubular cells': '-0.229', 'Endometrial stromal cells': '0.0', 'Ovarian stromal cells': '0.0', 'Undifferentiated cells': '0.0', 'T-cells': '0.0', 'B-cells': '0.0', 'Plasma cells': '0.0', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.1', 'Hofbauer cells': '0.0', 'Kupffer cells': '0.0', 'Dendritic cells': '0.0', 'Langerhans cells': '-0.089', 'Erythroid cells': '-0.053', 'Adipocytes (Subcutaneous)': '0.094', 'Adipocytes (Visceral)': '0.021', 'Breast glandular cells (progenitors)': '-0.003', 'Adipocytes (Breast)': '0.004', 'Colon enterocytes': '0.021', 'Colon enteroendocrine cells': '-0.157', 'Enteric glia cells': '-0.010', 'Mitotic cells (Colon)': '-0.067', 'Mitotic cells (Heart)': '-0.047', 'Podocytes': '0.115', 'Ascending Loop of Henle cells': '-0.144', 'Intercalated cells': '0.140', 'Cholangiocyte': '-0.116', 'NK-cells (Liver)': '0.175', 'Respiratory ciliated cells': '-0.019', 'Mitotic cells (Lung)': '0.003', 'NK-cells (Lung)': '-0.094', 'B-cells (Lung)': '-0.075', 'Alpha cells': '0.158', 'Beta cells': '0.167', 'Prostate glandular cells': '-0.033', 'Prostate basal glandular cells': '-0.078', 'Urothelial cells': '-0.013', 'Keratinocyte (other)': '0.054', 'Keratinocyte (granular)': '0.015', 'Hair cortex cells': '-0.052', 'Inner root sheath cells': '0.000', 'Outer root sheath cells': '-0.069', 'Sebaceous gland cells': '0.021', 'Eccrine sweat gland cells': '-0.054', 'Adipocytes (Skin)': '-0.047', 'Mitotic cells (Skin)': '0.035', 'Parietal cells': '-0.013', 'Chief cells': '0.025', 'Gastric mucous cells': '-0.009', 'Gastric enteroendocrine cells': '-0.012', 'Mitotic cells (Stomach)': '-0.038', 'Parafollicular cells': '0.133', 'Thyroid glandular cells': '0.019', 'Mitotic cells (Thyroid)': '0.054', 'Adrenal cortex cells': '-0.010', 'Adrenal medulla cells': '0.005', 'Mitotic cells (Adrenal gland)': '-0.018', 'Minor salivary glandular cells': '0.017', 'Minor salivary gland ductal cells': '-0.007', 'Minor salivary gland basal cells': '-0.081', 'Mitotic cells (Minor salivary gland)': '-0.072', 'Adipocytes (Minor salivary gland)': '0.025', 'Somatotropes': '0.091', 'Lactotropes': '-0.001', 'Gonadotropes': '-0.050', 'Corticotropes': '-0.037', 'Thyrotropes': '0.003', 'Undifferentiated cells (Pituitary gland)': '0.058', 'Mitotic cells (Spleen)': '-0.068', 'Platelets': '-0.015', 'Erythrocytes': '-0.026', 'Hematopoietic stem cells': '-0.018', 'B-cells (Spleen)': '-0.009', 'NK-cells (Spleen)': '-0.010', 'Amygdala excitatory': '0.0', 'Cerebellar inhibitory': '0.0', 'Cge interneuron': '0.0', 'Deep-layer corticothalamic and 6b': '0.0', 'Deep-layer intratelencephalic': '0.0', 'Deep-layer near-projecting': '0.0', 'Eccentric medium spiny neuron': '0.0', 'Hippocampal ca1-3': '0.0', 'Hippocampal ca4': '0.0', 'Hippocampal dentate gyrus': '0.0', 'Lamp5-lhx6 and chandelier': '0.0', 'Lower rhombic lip': '0.0', 'Mammillary body': '0.0', 'Medium spiny neuron': '0.0', 'Mge interneuron': '0.0', 'Midbrain-derived inhibitory': '0.0', 'Miscellaneous': '0.0', 'Splatter': '0.0', 'Thalamic excitatory': '0.0', 'Upper rhombic lip': '0.0', 'Upper-layer intratelencephalic': '0.0', 'Astrocyte': '0.0', 'Bergmann glia': '0.0', 'Central nervous system macrophage': '0.0', 'Choroid plexus epithelial cell': '0.0', 'Committed oligodendrocyte precursor': '0.0', 'Ependymal cell': '0.0', 'Oligodendrocyte': '0.0', 'Oligodendrocyte precursor cell': '0.0', 'Endothelial cell': '0.0', 'Pericyte': '0.0', 'Vascular associated smooth muscle cell': '0.0', 'Fibroblast': '0.0', 'Leukocyte': '0.0', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
3WKJ, 5GSU, 5GT3, 6BIY
{}
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[56.59, 60.83, 48.63, 52.75, 46.07, 52.72, 51.81, 43.63, 52.35, 53.04, 58.61, 59.24, 55.25, 51.9, 52.78, 57.76, 60.61, 65.98, 61.69, 68.22, 69.82, 62.14, 62.62, 61.08, 54.81, 59.75, 53.68, 55.99, 59.18, 60.28, 58.55, 63.13, 60.77, 61.59, 64.86, 70.6, 79.16, 90.72, 94.33, 93.69, 94.36, 95.79, 96.92, 96.56, 97.35, 97.21, 97.76, 98.02, 97.68, 97.96, 97.86, 97.67, 97.72, 97.25, 96.9, 97.72, 97.65, 96.18, 97.41, 97.96, 96.49, 96.09, 97.61, 97.73, 96.08, 96.91, 97.51, 97.14, 96.41, 97.27, 97.03, 97.42, 97.54, 98.12, 98.1, 98.04, 98.2, 98.16, 98.27, 97.95, 97.89, 97.86, 97.67, 96.9, 96.55, 95.33, 96.44, 95.7, 95.72, 97.33, 97.37, 96.23, 94.72, 94.89, 96.55, 97.75, 96.7, 97.22, 97.9, 97.97, 96.89, 97.38, 97.43, 96.42, 96.73, 95.88, 96.61, 96.83, 97.02, 96.98, 97.46, 97.28, 97.0, 97.18, 96.9, 96.57, 96.08, 96.06, 95.13, 94.38, 94.69, 96.07, 94.79, 94.75, 95.23, 93.1, 76.46]
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RING finger
Component of the RNF20/40 E3 ubiquitin-protein ligase complex
RNF20/40
null
H2B, RB1, WAC
H2B
mono
null
UBE2E1, UBE2B, UBE2A
null
null
72.436484
0.620949
85.44252
0.602362
2,841
O75150
Q9UQ80
22199232, BioGrid E3Net
UbiNet, UbiBrowser, 31181401
RNF40
MSGPGNKRAAGDGGSGPPEKKLSREEKTTTTLIEPIRLGGISSTEEMDLKVLQFKNKKLAERLEQRQACEDELRERIEKLEKRQATDDATLLIVNRYWAQLDETVEALLRCHESQGELSSAPEAPGTQEGPTCDGTPLPEPGTSELRDPLLMQLRPPLSEPALAFVVALGASSSEEVELELQGRMEFSKAAVSRVVEASDRLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLATKNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQNLAANEQAGPINREMRHLISSLQNHNHQLKGDAQRYKRKLREVQAEIGKLRAQASGSAHSTPNLGHPEDSGVSAPAPGKEEGGPGPVSTPDNRKEMAPVPGTTTTTTSVKKEELVPSEEDFQGITPGAQGPSSRGREPEARPKRELREREGPSLGPPPVASALSRADREKAKVEETKRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLSEMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQIHKLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKAVEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLKRAQEDISRLRRKLEKQRKVEVYADADEILQEEIKEYKARLTCPCCNTRKKDAVLTKCFHVFCFECVRGRYEARQRKCPKCNAAFGAHDFHRIYIS
Homo sapiens
Nucleus
Low tissue specificity
{'Ciliated cells': '17.9', 'Basal respiratory cells': '10.3', 'Club cells': '16.3', 'Ionocytes': '9.6', 'Mucus glandular cells': '14.5', 'Serous glandular cells': '14.6', 'Gastric mucus-secreting cells': '23.6', 'Proximal enterocytes': '22.1', 'Paneth cells': '26.2', 'Distal enterocytes': '30.4', 'Intestinal goblet cells': '25.6', 'Exocrine glandular cells': '-0.664', 'Basal prostatic cells': '26.0', 'Prostatic glandular cells': '18.7', 'Breast glandular cells': '0.601', 'Breast myoepithelial cells': '0.577', 'Glandular and luminal cells': '27.3', 'Secretory cells': '16.8', 'Basal keratinocytes': '19.2', 'Suprabasal keratinocytes': '21.2', 'Basal squamous epithelial cells': '18.0', 'Squamous epithelial cells': '20.6', 'Alveolar cells type 1': '0.193', 'Alveolar cells type 2': '0.263', 'Salivary duct cells': '16.0', 'Ductal cells': '0.618', 'Hepatocytes': '0.565', 'Cholangiocytes': '22.9', 'Proximal tubular cells': '0.208', 'Distal tubular cells': '64.5', 'Collecting duct cells': '25.3', 'Mesothelial cells': '0.426', 'Sertoli cells': '0.081', 'Granulosa cells': '13.8', 'Enteroendocrine cells': '29.5', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '-0.048', 'Excitatory neurons': '10.0', 'Inhibitory neurons': '10.7', 'Cone photoreceptor cells': '17.0', 'Rod photoreceptor cells': '9.5', 'Bipolar cells': '11.7', 'Horizontal cells': '16.4', 'Astrocytes': '17.3', 'Oligodendrocyte precursor cells': '12.3', 'Oligodendrocytes': '8.0', 'Microglial cells': '4.5', 'Muller glia cells': '16.6', 'Schwann cells': '0.053', 'Spermatogonia': '0.256', 'Spermatocytes': '0.525', 'Early spermatids': '0.441', 'Late spermatids': '0.100', 'Oocytes': '14.0', 'Cytotrophoblasts': '16.2', 'Syncytiotrophoblasts': '20.6', 'Extravillous trophoblasts': '16.0', 'Endothelial cells': '16.3', 'Lymphatic endothelial cells': '13.5', 'Cardiomyocytes': '0.608', 'Skeletal myocytes': '-0.278', 'Smooth muscle cells': '14.8', 'Adipocytes': '12.9', 'Melanocytes': '0.259', 'Fibroblasts': '14.8', 'Peritubular cells': '-0.022', 'Endometrial stromal cells': '19.9', 'Ovarian stromal cells': '14.0', 'Undifferentiated cells': '22.9', 'T-cells': '16.4', 'B-cells': '17.4', 'Plasma cells': '20.0', 'Nk-cells': '16.3', 'Granulocytes': '8.8', 'Monocytes': '17.6', 'Macrophages': '18.8', 'Hofbauer cells': '20.7', 'Kupffer cells': '20.4', 'Dendritic cells': '18.3', 'Langerhans cells': '0.357', 'Erythroid cells': '-0.165', 'Adipocytes (Subcutaneous)': '-0.241', 'Adipocytes (Visceral)': '-0.070', 'Breast glandular cells (progenitors)': '0.525', 'Adipocytes (Breast)': '-0.522', 'Colon enterocytes': '0.060', 'Colon enteroendocrine cells': '0.199', 'Enteric glia cells': '-0.333', 'Mitotic cells (Colon)': '0.017', 'Mitotic cells (Heart)': '0.487', 'Podocytes': '-0.142', 'Ascending Loop of Henle cells': '0.480', 'Intercalated cells': '0.015', 'Cholangiocyte': '0.343', 'NK-cells (Liver)': '-0.361', 'Respiratory ciliated cells': '-0.021', 'Mitotic cells (Lung)': '0.064', 'NK-cells (Lung)': '-0.063', 'B-cells (Lung)': '-0.177', 'Alpha cells': '0.421', 'Beta cells': '0.208', 'Prostate glandular cells': '0.231', 'Prostate basal glandular cells': '0.379', 'Urothelial cells': '0.144', 'Keratinocyte (other)': '0.412', 'Keratinocyte (granular)': '0.060', 'Hair cortex cells': '-0.020', 'Inner root sheath cells': '-0.005', 'Outer root sheath cells': '0.092', 'Sebaceous gland cells': '0.034', 'Eccrine sweat gland cells': '-0.115', 'Adipocytes (Skin)': '-0.134', 'Mitotic cells (Skin)': '0.294', 'Parietal cells': '-0.521', 'Chief cells': '-0.459', 'Gastric mucous cells': '-0.223', 'Gastric enteroendocrine cells': '-0.355', 'Mitotic cells (Stomach)': '0.171', 'Parafollicular cells': '0.135', 'Thyroid glandular cells': '0.508', 'Mitotic cells (Thyroid)': '-0.079', 'Adrenal cortex cells': '0.597', 'Adrenal medulla cells': '0.033', 'Mitotic cells (Adrenal gland)': '0.445', 'Minor salivary glandular cells': '0.475', 'Minor salivary gland ductal cells': '0.114', 'Minor salivary gland basal cells': '0.410', 'Mitotic cells (Minor salivary gland)': '0.369', 'Adipocytes (Minor salivary gland)': '0.171', 'Somatotropes': '-0.052', 'Lactotropes': '-0.082', 'Gonadotropes': '0.059', 'Corticotropes': '-0.087', 'Thyrotropes': '0.020', 'Undifferentiated cells (Pituitary gland)': '0.313', 'Mitotic cells (Spleen)': '-0.010', 'Platelets': '-0.035', 'Erythrocytes': '-0.068', 'Hematopoietic stem cells': '-0.175', 'B-cells (Spleen)': '0.282', 'NK-cells (Spleen)': '0.212', 'Amygdala excitatory': '15.9', 'Cerebellar inhibitory': '16.9', 'Cge interneuron': '17.8', 'Deep-layer corticothalamic and 6b': '15.2', 'Deep-layer intratelencephalic': '15.1', 'Deep-layer near-projecting': '16.1', 'Eccentric medium spiny neuron': '16.9', 'Hippocampal ca1-3': '18.4', 'Hippocampal ca4': '16.8', 'Hippocampal dentate gyrus': '13.9', 'Lamp5-lhx6 and chandelier': '17.2', 'Lower rhombic lip': '10.6', 'Mammillary body': '12.5', 'Medium spiny neuron': '15.9', 'Mge interneuron': '17.6', 'Midbrain-derived inhibitory': '18.7', 'Miscellaneous': '16.2', 'Splatter': '14.0', 'Thalamic excitatory': '16.0', 'Upper rhombic lip': '16.0', 'Upper-layer intratelencephalic': '15.1', 'Astrocyte': '22.9', 'Bergmann glia': '21.5', 'Central nervous system macrophage': '17.7', 'Choroid plexus epithelial cell': '12.2', 'Committed oligodendrocyte precursor': '19.3', 'Ependymal cell': '19.0', 'Oligodendrocyte': '11.2', 'Oligodendrocyte precursor cell': '17.7', 'Endothelial cell': '16.8', 'Pericyte': '19.8', 'Vascular associated smooth muscle cell': '17.8', 'Fibroblast': '17.6', 'Leukocyte': '16.3', 'Basophil': '88.5', 'Eosinophil': '17.2', 'Neutrophil': '140.5', 'Classical monocyte': '33.0', 'Non-classical monocyte': '24.4', 'Intermediate monocyte': '86.7', 'T-reg': '52.8', 'GdT-cell': '13.2', 'MAIT T-cell': '79.6', 'Memory CD4 T-cell': '7.2', 'Naive CD4 T-cell': '18.0', 'Memory CD8 T-cell': '10.0', 'Naive CD8 T-cell': '24.5', 'Memory B-cell': '8.1', 'Naive B-cell': '16.9', 'Plasmacytoid DC': '68.0', 'Myeloid DC': '69.2', 'NK-cell': '38.9', 'Total PBMC': '59.4', 'Vd2 gdTCR': '70.5', 'Memory CD4 T-cell Th1\\/Th17': '19.1', 'Memory CD4 T-cell Th17': '21.5', 'Memory CD4 T-cell Th2': '22.8', 'Non-Vd2 gdTCR': '78.7', 'Memory CD4 T-cell Th1': '28.1', 'Memory CD4 T-cell TFH': '33.1', 'Terminal effector memory CD4 T-cell': '69.4', 'Central memory CD8 T-cell': '62.9', 'Effector memory CD8 T-cell': '83.9', 'Terminal effector memory CD8 T-cell': '74.8', 'Non-switched memory B-cell': '49.5', 'Plasmablast': '59.3', 'Switched memory B-cell': '59.0', 'Exhausted memory B-cell': '63.9', 'Progenitor cell': '78.3', 'Naive CD4 T-cell activated': '13.9', 'Naive CD8 T-cell activated': '24.6', 'Memory T-reg': '32.7', 'Naive T-reg': '25.3'}
8GUI, 8GUJ, 8IEJ
{'Adipose Tissue': 35.89617940199336, 'Adrenal Gland': 35.863279069767444, 'Bladder': 38.30285714285714, 'Blood': 35.896346609257265, 'Blood Vessel': 42.135866666666665, 'Brain': 24.48113580620742, 'Breast': 40.03095860566449, 'Cervix Uteri': 52.26894736842105, 'Colon': 31.54429396662388, 'Esophagus': 34.059725259515574, 'Fallopian Tube': 48.76555555555555, 'Heart': 13.445284552845528, 'Kidney': 20.505415730337077, 'Liver': 12.66583628318584, 'Lung': 40.21266435986159, 'Muscle': 14.072226650062266, 'Nerve': 48.54226171243942, 'Ovary': 54.63477777777778, 'Pancreas': 14.481707317073171, 'Pituitary': 38.49226148409894, 'Prostate': 39.41742857142857, 'Salivary Gland': 35.94524691358025, 'Skin': 48.537831951354335, 'Small Intestine': 33.137647058823525, 'Spleen': 32.4444398340249, 'Stomach': 27.62590529247911, 'Testis': 73.01493074792243, 'Thyroid': 54.08897396630934, 'Uterus': 54.04042253521126, 'Vagina': 42.33967948717949}
PA2G4
MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQSSASRKTQKKKKKKASKTAENATSGETLEENEAGD
Homo sapiens
Cytoplasm, Nucleus, nucleolus, Cytoplasm
Low tissue specificity
{'Ciliated cells': '109.3', 'Basal respiratory cells': '176.4', 'Club cells': '132.4', 'Ionocytes': '110.4', 'Mucus glandular cells': '131.8', 'Serous glandular cells': '143.2', 'Gastric mucus-secreting cells': '106.7', 'Proximal enterocytes': '119.2', 'Paneth cells': '122.3', 'Distal enterocytes': '99.0', 'Intestinal goblet cells': '116.3', 'Exocrine glandular cells': '-0.794', 'Basal prostatic cells': '138.0', 'Prostatic glandular cells': '96.9', 'Breast glandular cells': '0.183', 'Breast myoepithelial cells': '-0.007', 'Glandular and luminal cells': '155.3', 'Secretory cells': '226.0', 'Basal keratinocytes': '415.5', 'Suprabasal keratinocytes': '487.8', 'Basal squamous epithelial cells': '248.4', 'Squamous epithelial cells': '282.6', 'Alveolar cells type 1': '-0.055', 'Alveolar cells type 2': '-0.006', 'Salivary duct cells': '136.0', 'Ductal cells': '0.532', 'Hepatocytes': '0.421', 'Cholangiocytes': '108.7', 'Proximal tubular cells': '0.233', 'Distal tubular cells': '227.4', 'Collecting duct cells': '138.1', 'Mesothelial cells': '0.011', 'Sertoli cells': '-0.443', 'Granulosa cells': '137.6', 'Enteroendocrine cells': '111.9', 'Pancreatic endocrine cells': '222.4', 'Leydig cells': '-0.457', 'Excitatory neurons': '12.4', 'Inhibitory neurons': '12.5', 'Cone photoreceptor cells': '42.5', 'Rod photoreceptor cells': '37.3', 'Bipolar cells': '45.3', 'Horizontal cells': '25.2', 'Astrocytes': '9.3', 'Oligodendrocyte precursor cells': '9.9', 'Oligodendrocytes': '13.8', 'Microglial cells': '6.3', 'Muller glia cells': '107.9', 'Schwann cells': '0.031', 'Spermatogonia': '-0.244', 'Spermatocytes': '0.084', 'Early spermatids': '0.839', 'Late spermatids': '0.612', 'Oocytes': '202.9', 'Cytotrophoblasts': '257.4', 'Syncytiotrophoblasts': '198.2', 'Extravillous trophoblasts': '301.2', 'Endothelial cells': '152.9', 'Lymphatic endothelial cells': '156.3', 'Cardiomyocytes': '0.568', 'Skeletal myocytes': '-0.299', 'Smooth muscle cells': '165.0', 'Adipocytes': '145.3', 'Melanocytes': '0.305', 'Fibroblasts': '146.8', 'Peritubular cells': '-0.347', 'Endometrial stromal cells': '229.8', 'Ovarian stromal cells': '183.5', 'Undifferentiated cells': '291.5', 'T-cells': '160.0', 'B-cells': '109.9', 'Plasma cells': '197.2', 'Nk-cells': '167.8', 'Granulocytes': '198.0', 'Monocytes': '116.2', 'Macrophages': '133.7', 'Hofbauer cells': '194.6', 'Kupffer cells': '120.1', 'Dendritic cells': '163.0', 'Langerhans cells': '0.162', 'Erythroid cells': '-0.117', 'Adipocytes (Subcutaneous)': '0.191', 'Adipocytes (Visceral)': '0.055', 'Breast glandular cells (progenitors)': '0.143', 'Adipocytes (Breast)': '0.010', 'Colon enterocytes': '-0.164', 'Colon enteroendocrine cells': '0.182', 'Enteric glia cells': '-0.125', 'Mitotic cells (Colon)': '-0.127', 'Mitotic cells (Heart)': '0.485', 'Podocytes': '-0.027', 'Ascending Loop of Henle cells': '0.355', 'Intercalated cells': '-0.017', 'Cholangiocyte': '0.333', 'NK-cells (Liver)': '-0.395', 'Respiratory ciliated cells': '-0.080', 'Mitotic cells (Lung)': '-0.038', 'NK-cells (Lung)': '-0.041', 'B-cells (Lung)': '-0.146', 'Alpha cells': '0.315', 'Beta cells': '0.115', 'Prostate glandular cells': '-0.211', 'Prostate basal glandular cells': '0.176', 'Urothelial cells': '0.220', 'Keratinocyte (other)': '0.416', 'Keratinocyte (granular)': '0.165', 'Hair cortex cells': '0.015', 'Inner root sheath cells': '0.078', 'Outer root sheath cells': '-0.064', 'Sebaceous gland cells': '-0.064', 'Eccrine sweat gland cells': '-0.373', 'Adipocytes (Skin)': '-0.285', 'Mitotic cells (Skin)': '0.232', 'Parietal cells': '-0.589', 'Chief cells': '-0.411', 'Gastric mucous cells': '-0.270', 'Gastric enteroendocrine cells': '-0.357', 'Mitotic cells (Stomach)': '0.194', 'Parafollicular cells': '0.091', 'Thyroid glandular cells': '0.305', 'Mitotic cells (Thyroid)': '-0.085', 'Adrenal cortex cells': '0.380', 'Adrenal medulla cells': '0.063', 'Mitotic cells (Adrenal gland)': '0.162', 'Minor salivary glandular cells': '0.253', 'Minor salivary gland ductal cells': '-0.312', 'Minor salivary gland basal cells': '0.725', 'Mitotic cells (Minor salivary gland)': '0.775', 'Adipocytes (Minor salivary gland)': '0.242', 'Somatotropes': '-0.123', 'Lactotropes': '-0.246', 'Gonadotropes': '-0.233', 'Corticotropes': '-0.034', 'Thyrotropes': '-0.004', 'Undifferentiated cells (Pituitary gland)': '0.230', 'Mitotic cells (Spleen)': '0.181', 'Platelets': '-0.071', 'Erythrocytes': '-0.063', 'Hematopoietic stem cells': '-0.075', 'B-cells (Spleen)': '0.272', 'NK-cells (Spleen)': '-0.035', 'Amygdala excitatory': '19.2', 'Cerebellar inhibitory': '30.7', 'Cge interneuron': '34.9', 'Deep-layer corticothalamic and 6b': '21.1', 'Deep-layer intratelencephalic': '21.7', 'Deep-layer near-projecting': '23.1', 'Eccentric medium spiny neuron': '23.6', 'Hippocampal ca1-3': '19.7', 'Hippocampal ca4': '28.4', 'Hippocampal dentate gyrus': '27.1', 'Lamp5-lhx6 and chandelier': '31.9', 'Lower rhombic lip': '25.8', 'Mammillary body': '20.4', 'Medium spiny neuron': '20.4', 'Mge interneuron': '23.5', 'Midbrain-derived inhibitory': '29.7', 'Miscellaneous': '26.6', 'Splatter': '25.9', 'Thalamic excitatory': '26.6', 'Upper rhombic lip': '44.6', 'Upper-layer intratelencephalic': '23.6', 'Astrocyte': '19.2', 'Bergmann glia': '36.8', 'Central nervous system macrophage': '33.8', 'Choroid plexus epithelial cell': '19.9', 'Committed oligodendrocyte precursor': '37.4', 'Ependymal cell': '29.2', 'Oligodendrocyte': '37.0', 'Oligodendrocyte precursor cell': '34.8', 'Endothelial cell': '39.3', 'Pericyte': '58.0', 'Vascular associated smooth muscle cell': '49.0', 'Fibroblast': '26.4', 'Leukocyte': '56.2', 'Basophil': '114.4', 'Eosinophil': '54.7', 'Neutrophil': '15.7', 'Classical monocyte': '36.3', 'Non-classical monocyte': '37.8', 'Intermediate monocyte': '180.2', 'T-reg': '269.0', 'GdT-cell': '130.2', 'MAIT T-cell': '317.9', 'Memory CD4 T-cell': '137.2', 'Naive CD4 T-cell': '64.3', 'Memory CD8 T-cell': '141.3', 'Naive CD8 T-cell': '62.8', 'Memory B-cell': '98.4', 'Naive B-cell': '29.8', 'Plasmacytoid DC': '279.0', 'Myeloid DC': '243.0', 'NK-cell': '69.2', 'Total PBMC': '236.2', 'Vd2 gdTCR': '290.9', 'Memory CD4 T-cell Th1\\/Th17': '63.7', 'Memory CD4 T-cell Th17': '60.4', 'Memory CD4 T-cell Th2': '57.3', 'Non-Vd2 gdTCR': '277.6', 'Memory CD4 T-cell Th1': '57.2', 'Memory CD4 T-cell TFH': '55.6', 'Terminal effector memory CD4 T-cell': '218.0', 'Central memory CD8 T-cell': '274.4', 'Effector memory CD8 T-cell': '309.0', 'Terminal effector memory CD8 T-cell': '310.7', 'Non-switched memory B-cell': '195.4', 'Plasmablast': '306.4', 'Switched memory B-cell': '200.2', 'Exhausted memory B-cell': '179.4', 'Progenitor cell': '222.3', 'Memory T-reg': '61.5', 'Naive CD4 T-cell activated': '235.8', 'Naive CD8 T-cell activated': '237.4', 'Naive T-reg': '62.7'}
2Q8K, 3J2I, 6CHT, 6LSR, 6SXO, 6WM8, 6Z6L, 6Z6M, 6Z6N, 6ZM7, 6ZME, 6ZMI, 6ZMO, 7BHP
{'Adipose Tissue': 90.47207641196012, 'Adrenal Gland': 58.96748062015504, 'Bladder': 93.04761904761904, 'Blood': 80.00492895586652, 'Blood Vessel': 96.90147565543072, 'Brain': 45.94096669190007, 'Breast': 86.34485838779956, 'Cervix Uteri': 94.52368421052633, 'Colon': 80.48509627727856, 'Esophagus': 99.44723183391004, 'Fallopian Tube': 97.79777777777775, 'Heart': 41.08832288037166, 'Kidney': 41.81966292134831, 'Liver': 34.67757522123894, 'Lung': 90.2344982698962, 'Muscle': 79.71844333748444, 'Nerve': 104.98930533117932, 'Ovary': 92.76011111111112, 'Pancreas': 38.63761280487805, 'Pituitary': 50.65381625441697, 'Prostate': 71.68359183673469, 'Salivary Gland': 67.6138888888889, 'Skin': 144.12140409065782, 'Small Intestine': 70.27235294117648, 'Spleen': 75.45228215767635, 'Stomach': 65.27108635097493, 'Testis': 97.14650969529086, 'Thyroid': 80.04434915773354, 'Uterus': 97.12478873239436, 'Vagina': 103.96089743589744}
[38.7, 39.64, 35.6, 37.72, 36.84, 33.09, 39.61, 33.17, 40.8, 37.22, 38.94, 36.15, 31.2, 34.39, 36.06, 33.43, 38.09, 42.58, 37.78, 37.92, 37.38, 38.75, 37.56, 38.45, 37.77, 39.04, 41.48, 39.52, 42.67, 40.01, 45.24, 40.63, 45.89, 42.49, 51.66, 56.27, 59.87, 58.29, 61.8, 67.6, 66.44, 77.0, 84.15, 80.25, 81.31, 80.93, 77.46, 81.44, 81.19, 83.14, 84.25, 86.73, 82.46, 83.13, 86.45, 85.63, 89.79, 88.2, 90.08, 90.71, 89.8, 92.18, 91.51, 92.6, 89.77, 93.05, 94.32, 92.24, 92.95, 92.42, 93.89, 93.15, 93.25, 94.71, 93.58, 94.28, 91.37, 93.75, 91.69, 91.71, 91.64, 89.96, 90.12, 86.16, 84.0, 82.27, 84.18, 84.53, 81.8, 81.92, 80.86, 80.4, 78.14, 78.72, 79.45, 80.08, 77.37, 80.76, 79.78, 76.81, 78.32, 78.97, 79.75, 76.57, 77.2, 78.96, 77.49, 74.62, 77.22, 78.98, 70.18, 67.31, 70.61, 57.3, 52.23, 51.12, 47.49, 41.16, 41.55, 33.33, 32.22, 37.04, 31.7, 33.25, 30.97, 30.54, 29.87, 33.58, 30.28, 24.57, 38.28, 26.8, 33.71, 31.22, 27.2, 33.42, 31.43, 29.19, 35.76, 30.56, 33.26, 30.28, 32.35, 32.05, 33.8, 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[32.2, 40.14, 37.53, 43.93, 42.95, 46.27, 62.72, 75.04, 89.77, 96.24, 97.69, 97.98, 97.5, 97.72, 97.21, 97.27, 98.32, 98.44, 98.32, 98.63, 98.81, 98.68, 98.46, 98.77, 98.84, 98.75, 98.84, 98.9, 98.86, 98.67, 98.85, 98.86, 98.72, 98.72, 98.84, 98.59, 98.21, 98.55, 98.59, 98.37, 98.48, 98.42, 98.69, 98.73, 98.77, 98.64, 98.58, 98.85, 98.83, 98.65, 98.77, 98.87, 98.83, 98.75, 98.78, 98.84, 98.4, 98.51, 98.58, 98.09, 97.52, 97.86, 97.7, 96.28, 96.03, 96.5, 95.55, 92.44, 93.24, 95.72, 95.87, 97.2, 98.17, 98.76, 98.81, 98.88, 98.8, 98.91, 98.87, 98.86, 98.81, 98.84, 98.81, 98.6, 98.69, 98.74, 98.36, 98.52, 98.61, 98.56, 97.63, 97.97, 96.95, 96.47, 93.97, 94.01, 94.27, 98.18, 98.73, 98.82, 98.69, 98.22, 98.21, 98.79, 98.85, 98.89, 98.91, 98.9, 98.91, 98.86, 98.85, 98.89, 98.74, 98.51, 97.63, 97.87, 98.7, 98.88, 98.9, 98.86, 98.88, 98.9, 98.86, 98.9, 98.75, 98.69, 98.55, 97.45, 96.64, 92.56, 90.38, 92.46, 95.0, 96.93, 98.12, 98.21, 97.98, 98.4, 98.63, 98.65, 98.63, 98.81, 98.83, 98.36, 98.63, 98.79, 98.48, 98.25, 98.61, 98.47, 97.97, 98.11, 98.34, 97.27, 97.25, 97.64, 98.05, 96.68, 97.23, 97.07, 97.85, 98.2, 98.23, 97.75, 98.0, 98.53, 98.39, 97.36, 97.85, 98.55, 97.65, 97.71, 98.25, 98.42, 97.8, 97.93, 98.32, 98.18, 98.72, 98.77, 98.82, 98.77, 98.44, 97.75, 98.05, 98.36, 98.75, 98.67, 98.74, 98.75, 98.35, 98.12, 97.32, 97.92, 98.23, 96.07, 96.81, 96.21, 98.51, 98.68, 98.75, 98.56, 98.71, 98.1, 97.92, 97.32, 96.53, 97.1, 97.34, 95.76, 96.34, 96.53, 97.44, 96.69, 96.87, 97.42, 98.38, 98.5, 98.32, 97.78, 98.12, 98.62, 98.82, 98.89, 98.85, 98.83, 98.8, 98.86, 98.86, 98.93, 98.9, 98.79, 98.42, 97.9, 98.19, 97.78, 97.04, 96.76, 94.06, 88.55, 89.89, 93.48, 95.87, 97.92, 98.39, 98.75, 98.79, 98.65, 98.42, 97.58, 95.7, 95.15, 96.41, 95.44, 97.09, 97.26, 97.81, 97.73, 97.49, 97.59, 97.59, 98.2, 98.13, 97.97, 98.49, 98.29, 97.79, 97.91, 97.99, 96.07, 95.36, 95.26, 96.67, 94.86, 97.08, 98.47, 98.74, 98.8, 98.64, 98.55, 98.05, 98.0, 98.06, 95.26, 96.82, 97.12, 96.8, 97.21, 98.07, 97.3, 97.42, 97.55, 98.11, 98.08, 98.35, 98.49, 98.12, 98.07, 98.12, 97.97, 98.31, 98.59, 98.04, 98.12, 98.2, 97.74, 98.11, 98.28, 98.6, 98.23, 97.44, 96.62, 97.26, 98.61, 98.85, 98.91, 98.91, 98.88, 98.84, 98.9, 98.88, 98.9, 98.75, 98.66, 98.31, 97.29, 94.83, 92.14, 92.32, 97.22, 97.65, 98.25, 98.65, 98.84, 98.06, 96.78, 96.55, 97.25, 95.92, 93.61, 95.09, 97.46, 98.11, 97.97, 97.68, 97.1, 97.08, 95.67, 95.97, 90.55, 92.65, 94.2, 92.28, 93.07, 94.51, 94.77, 94.44, 93.27, 91.22, 88.81, 81.24, 73.0, 66.87, 58.74, 53.3, 53.32, 54.77, 55.2, 54.81, 57.19, 57.77, 54.0, 57.17, 61.5, 58.02, 54.56, 60.59, 56.85, 53.99, 55.18, 53.48, 54.59, 48.77, 34.91, 38.69, 34.37, 42.32, 41.22, 37.66, 42.9, 36.42, 48.83, 39.31, 42.59]
[1.0, 0.89, 0.9, 0.87, 0.83, 0.91, 0.87, 0.89, 0.55, 0.32, 0.3, 0.03, 0.58, 0.49, 0.74, 0.54, 0.01, 0.1, 0.44, 0.05, 0.02, 0.41, 0.29, 0.0, 0.0, 0.54, 0.03, 0.0, 0.15, 0.52, 0.01, 0.0, 0.43, 0.24, 0.0, 0.2, 0.79, 0.24, 0.06, 0.39, 0.42, 0.62, 0.23, 0.27, 0.0, 0.16, 0.44, 0.03, 0.0, 0.36, 0.37, 0.0, 0.1, 0.52, 0.26, 0.0, 0.54, 0.61, 0.2, 0.01, 0.46, 0.48, 0.21, 0.22, 0.68, 0.95, 0.44, 0.88, 0.92, 0.18, 0.43, 0.26, 0.02, 0.2, 0.0, 0.05, 0.02, 0.0, 0.02, 0.01, 0.02, 0.11, 0.16, 0.18, 0.04, 0.0, 0.05, 0.2, 0.09, 0.01, 0.03, 0.0, 0.65, 0.61, 0.19, 0.86, 0.31, 0.31, 0.54, 0.02, 0.58, 0.75, 0.21, 0.07, 0.0, 0.0, 0.01, 0.0, 0.05, 0.0, 0.0, 0.0, 0.1, 0.0, 0.18, 0.0, 0.01, 0.0, 0.0, 0.03, 0.0, 0.03, 0.02, 0.0, 0.09, 0.12, 0.01, 0.47, 0.33, 0.57, 0.96, 0.96, 0.5, 0.52, 0.09, 0.64, 0.52, 0.34, 0.24, 0.0, 0.07, 0.0, 0.0, 0.26, 0.0, 0.0, 0.24, 0.26, 0.01, 0.04, 0.18, 0.01, 0.01, 0.12, 0.17, 0.11, 0.01, 0.41, 0.23, 0.53, 0.13, 0.29, 0.01, 0.37, 0.36, 0.01, 0.13, 0.62, 0.09, 0.01, 0.22, 0.45, 0.0, 0.0, 0.61, 0.23, 0.02, 0.63, 0.02, 0.23, 0.03, 0.0, 0.35, 0.23, 0.22, 0.34, 0.0, 0.26, 0.09, 0.04, 0.21, 0.3, 0.3, 0.34, 0.12, 0.46, 0.04, 0.68, 0.23, 0.12, 0.0, 0.09, 0.02, 0.24, 0.13, 0.32, 0.63, 0.6, 0.3, 0.56, 0.79, 0.65, 0.26, 0.86, 0.63, 0.15, 0.5, 0.02, 0.54, 0.54, 0.35, 0.1, 0.03, 0.01, 0.08, 0.0, 0.13, 0.01, 0.03, 0.01, 0.0, 0.09, 0.25, 0.49, 0.0, 0.52, 0.29, 0.64, 0.55, 0.63, 0.81, 0.32, 0.42, 0.16, 0.01, 0.0, 0.1, 0.04, 0.17, 0.13, 0.55, 0.83, 0.45, 0.93, 0.41, 0.66, 0.09, 0.71, 0.49, 0.75, 0.29, 0.0, 0.47, 0.53, 0.05, 0.17, 0.59, 0.3, 0.0, 0.44, 0.83, 0.55, 0.21, 0.22, 0.09, 0.03, 0.02, 0.02, 0.05, 0.02, 0.14, 0.35, 0.09, 0.97, 0.39, 0.22, 0.75, 0.56, 0.01, 0.38, 0.46, 0.0, 0.06, 0.66, 0.12, 0.0, 0.32, 0.83, 0.36, 0.53, 0.01, 0.02, 0.33, 0.55, 0.22, 0.35, 0.02, 0.2, 0.21, 0.08, 0.59, 0.9, 0.74, 0.32, 0.18, 0.0, 0.0, 0.03, 0.08, 0.11, 0.03, 0.0, 0.01, 0.0, 0.0, 0.22, 0.48, 0.55, 0.12, 0.15, 0.28, 0.32, 0.12, 0.01, 0.47, 0.26, 0.3, 0.21, 0.68, 0.52, 0.79, 0.3, 0.05, 0.46, 0.17, 0.84, 0.26, 0.55, 0.07, 0.66, 0.31, 0.66, 0.73, 0.05, 0.31, 0.55, 0.21, 0.18, 0.7, 0.34, 0.24, 0.24, 0.34, 0.48, 0.7, 0.44, 0.42, 0.72, 0.75, 0.56, 0.76, 0.7, 0.73, 0.56, 0.45, 0.68, 0.63, 0.51, 0.6, 0.68, 0.74, 0.78, 0.52, 0.76, 0.86, 0.84, 0.93, 0.89, 0.97, 0.98, 1.0, 0.93, 1.0, 1.0]
RING finger
Component of the RNF20/40 E3 ubiquitin-protein ligase complex
RNF20/40
null
H2B, RB1, WAC
H2B
mono
null
UBE2E1, UBE2B, UBE2A
null
null
72.436484
0.620949
92.648401
0.316827
2,002
O75159
P00533
15590694, E3Net
UbiNet, UbiBrowser, 31181401
SOCS5
MDKVGKMWNNFKYRCQNLFGHEGGSRSENVDMNSNRCLSVKEKNISIGDSTPQQQSSPLRENIALQLGLSPSKNSSRRNQNCATEIPQIVEISIEKDNDSCVTPGTRLARRDSYSRHAPWGGKKKHSCSTKTQSSLDADKKFGRTRSGLQRRERRYGVSSVHDMDSVSSRTVGSRSLRQRLQDTVGLCFPMRTYSKQSKPLFSNKRKIHLSELMLEKCPFPAGSDLAQKWHLIKQHTAPVSPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYKLGPKLAPGMTEISGDSSAIPQANCDSEEDTTTLCLQSRRQKQRQISGDSHTHVSRQGAWKVHTQIDYIHCLVPDLLQITGNPCYWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYNRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGLLEHYKDPSSCMFFEPLLTISLNRTFPFSLQYICRAVICRCTTYDGIDGLPLPSMLQDFLKEYHYKQKVRVRWLEREPVKAK
Homo sapiens
null
Low tissue specificity
{'Ciliated cells': '6.9', 'Basal respiratory cells': '7.7', 'Club cells': '8.2', 'Ionocytes': '3.3', 'Mucus glandular cells': '14.3', 'Serous glandular cells': '10.5', 'Gastric mucus-secreting cells': '9.4', 'Proximal enterocytes': '4.0', 'Paneth cells': '6.8', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '6.3', 'Exocrine glandular cells': '-0.552', 'Basal prostatic cells': '13.3', 'Prostatic glandular cells': '12.2', 'Breast glandular cells': '0.426', 'Breast myoepithelial cells': '0.656', 'Glandular and luminal cells': '10.8', 'Secretory cells': '10.6', 'Basal keratinocytes': '10.2', 'Suprabasal keratinocytes': '9.3', 'Basal squamous epithelial cells': '13.1', 'Squamous epithelial cells': '8.1', 'Alveolar cells type 1': '0.015', 'Alveolar cells type 2': '-0.316', 'Salivary duct cells': '16.0', 'Ductal cells': '0.618', 'Hepatocytes': '0.172', 'Cholangiocytes': '19.1', 'Proximal tubular cells': '0.065', 'Distal tubular cells': '12.3', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.533', 'Sertoli cells': '0.181', 'Granulosa cells': '12.1', 'Enteroendocrine cells': '5.6', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.244', 'Excitatory neurons': '41.9', 'Inhibitory neurons': '49.3', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '4.0', 'Bipolar cells': '11.5', 'Horizontal cells': '12.0', 'Astrocytes': '18.0', 'Oligodendrocyte precursor cells': '35.8', 'Oligodendrocytes': '23.7', 'Microglial cells': '17.9', 'Muller glia cells': '8.9', 'Schwann cells': '0.153', 'Spermatogonia': '0.433', 'Spermatocytes': '0.429', 'Early spermatids': '0.141', 'Late spermatids': '-0.193', 'Oocytes': '0.0', 'Cytotrophoblasts': '3.5', 'Syncytiotrophoblasts': '2.8', 'Extravillous trophoblasts': '3.0', 'Endothelial cells': '24.7', 'Lymphatic endothelial cells': '20.1', 'Cardiomyocytes': '0.511', 'Skeletal myocytes': '0.038', 'Smooth muscle cells': '20.8', 'Adipocytes': '17.8', 'Melanocytes': '0.069', 'Fibroblasts': '19.0', 'Peritubular cells': '0.213', 'Endometrial stromal cells': '25.2', 'Ovarian stromal cells': '17.3', 'Undifferentiated cells': '6.2', 'T-cells': '8.1', 'B-cells': '13.7', 'Plasma cells': '6.4', 'Nk-cells': '7.8', 'Granulocytes': '6.7', 'Monocytes': '5.6', 'Macrophages': '9.3', 'Hofbauer cells': '4.5', 'Kupffer cells': '8.0', 'Dendritic cells': '40.6', 'Langerhans cells': '0.131', 'Erythroid cells': '0.141', 'Adipocytes (Subcutaneous)': '-0.439', 'Adipocytes (Visceral)': '-0.392', 'Breast glandular cells (progenitors)': '0.291', 'Adipocytes (Breast)': '-0.562', 'Colon enterocytes': '-0.186', 'Colon enteroendocrine cells': '0.302', 'Enteric glia cells': '0.238', 'Mitotic cells (Colon)': '0.027', 'Mitotic cells (Heart)': '0.520', 'Podocytes': '-0.062', 'Ascending Loop of Henle cells': '0.414', 'Intercalated cells': '-0.062', 'Cholangiocyte': '0.284', 'NK-cells (Liver)': '-0.142', 'Respiratory ciliated cells': '-0.076', 'Mitotic cells (Lung)': '-0.011', 'NK-cells (Lung)': '0.117', 'B-cells (Lung)': '0.037', 'Alpha cells': '0.425', 'Beta cells': '0.262', 'Prostate glandular cells': '-0.457', 'Prostate basal glandular cells': '-0.022', 'Urothelial cells': '0.153', 'Keratinocyte (other)': '-0.122', 'Keratinocyte (granular)': '-0.305', 'Hair cortex cells': '0.193', 'Inner root sheath cells': '0.253', 'Outer root sheath cells': '0.404', 'Sebaceous gland cells': '0.179', 'Eccrine sweat gland cells': '0.283', 'Adipocytes (Skin)': '0.163', 'Mitotic cells (Skin)': '0.314', 'Parietal cells': '-0.649', 'Chief cells': '-0.534', 'Gastric mucous cells': '-0.545', 'Gastric enteroendocrine cells': '-0.405', 'Mitotic cells (Stomach)': '-0.126', 'Parafollicular cells': '0.020', 'Thyroid glandular cells': '0.118', 'Mitotic cells (Thyroid)': '0.166', 'Adrenal cortex cells': '0.587', 'Adrenal medulla cells': '0.034', 'Mitotic cells (Adrenal gland)': '0.379', 'Minor salivary glandular cells': '0.639', 'Minor salivary gland ductal cells': '0.363', 'Minor salivary gland basal cells': '0.072', 'Mitotic cells (Minor salivary gland)': '0.135', 'Adipocytes (Minor salivary gland)': '0.120', 'Somatotropes': '-0.244', 'Lactotropes': '-0.017', 'Gonadotropes': '0.088', 'Corticotropes': '-0.098', 'Thyrotropes': '0.213', 'Undifferentiated cells (Pituitary gland)': '0.399', 'Mitotic cells (Spleen)': '-0.244', 'Platelets': '-0.208', 'Erythrocytes': '-0.113', 'Hematopoietic stem cells': '-0.195', 'B-cells (Spleen)': '0.192', 'NK-cells (Spleen)': '0.169', 'Amygdala excitatory': '0.2', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.2', 'Eccentric medium spiny neuron': '0.2', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.1', 'Lamp5-lhx6 and chandelier': '0.2', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.2', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.2', 'Miscellaneous': '0.2', 'Splatter': '0.2', 'Thalamic excitatory': '0.1', 'Upper rhombic lip': '1.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '0.2', 'Bergmann glia': '0.1', 'Central nervous system macrophage': '0.3', 'Choroid plexus epithelial cell': '0.8', 'Committed oligodendrocyte precursor': '0.2', 'Ependymal cell': '0.1', 'Oligodendrocyte': '0.2', 'Oligodendrocyte precursor cell': '0.2', 'Endothelial cell': '0.3', 'Pericyte': '1.0', 'Vascular associated smooth muscle cell': '0.2', 'Fibroblast': '0.1', 'Leukocyte': '0.3', 'Basophil': '17.2', 'Eosinophil': '2.5', 'Neutrophil': '6.9', 'Classical monocyte': '11.8', 'Non-classical monocyte': '9.8', 'Intermediate monocyte': '5.1', 'T-reg': '9.8', 'GdT-cell': '0.9', 'MAIT T-cell': '11.8', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '19.9', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '18.3', 'Memory B-cell': '1.8', 'Naive B-cell': '33.1', 'Plasmacytoid DC': '6.9', 'Myeloid DC': '6.2', 'NK-cell': '19.2', 'Total PBMC': '6.0', 'Vd2 gdTCR': '11.3', 'Memory CD4 T-cell Th1\\/Th17': '22.5', 'Memory CD4 T-cell Th17': '16.2', 'Memory CD4 T-cell Th2': '17.7', 'Non-Vd2 gdTCR': '10.2', 'Memory CD4 T-cell Th1': '17.1', 'Memory CD4 T-cell TFH': '14.8', 'Terminal effector memory CD4 T-cell': '7.9', 'Central memory CD8 T-cell': '9.9', 'Effector memory CD8 T-cell': '9.2', 'Terminal effector memory CD8 T-cell': '10.5', 'Non-switched memory B-cell': '10.3', 'Plasmablast': '4.0', 'Switched memory B-cell': '7.5', 'Exhausted memory B-cell': '8.3', 'Progenitor cell': '22.8', 'Memory T-reg': '11.6', 'Naive CD4 T-cell activated': '13.0', 'Naive CD8 T-cell activated': '12.8', 'Naive T-reg': '22.4'}
null
{'Adipose Tissue': 20.25867275747508, 'Adrenal Gland': 12.75481007751938, 'Bladder': 17.15285714285714, 'Blood': 3.2172663078579116, 'Blood Vessel': 23.02793707865169, 'Brain': 11.608470704012111, 'Breast': 20.39918300653595, 'Cervix Uteri': 24.532894736842103, 'Colon': 14.292567394094991, 'Esophagus': 14.687253287197231, 'Fallopian Tube': 20.69, 'Heart': 7.649941114982578, 'Kidney': 6.783460674157303, 'Liver': 4.284588495575221, 'Lung': 17.046, 'Muscle': 6.806485678704857, 'Nerve': 21.98428109854604, 'Ovary': 27.972055555555556, 'Pancreas': 3.755094512195122, 'Pituitary': 11.138766784452296, 'Prostate': 14.877085714285714, 'Salivary Gland': 13.492506172839509, 'Skin': 18.830433388612494, 'Small Intestine': 11.817288770053477, 'Spleen': 13.593684647302904, 'Stomach': 9.558523676880224, 'Testis': 15.72264542936288, 'Thyroid': 16.437451761102604, 'Uterus': 25.595985915492957, 'Vagina': 17.663628205128205}
EGFR
MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA
Homo sapiens
Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus membrane, Nucleus membrane, Endosome, Endosome membrane, Nucleus, Secreted
Tissue enhanced (placenta)
{'Ciliated cells': '23.3', 'Basal respiratory cells': '96.6', 'Club cells': '57.1', 'Ionocytes': '40.5', 'Mucus glandular cells': '109.0', 'Serous glandular cells': '72.1', 'Gastric mucus-secreting cells': '25.9', 'Proximal enterocytes': '13.4', 'Paneth cells': '11.6', 'Distal enterocytes': '30.6', 'Intestinal goblet cells': '23.0', 'Exocrine glandular cells': '-0.656', 'Basal prostatic cells': '78.0', 'Prostatic glandular cells': '46.6', 'Breast glandular cells': '0.211', 'Breast myoepithelial cells': '0.205', 'Glandular and luminal cells': '34.1', 'Secretory cells': '26.2', 'Basal keratinocytes': '96.1', 'Suprabasal keratinocytes': '94.9', 'Basal squamous epithelial cells': '98.8', 'Squamous epithelial cells': '66.9', 'Alveolar cells type 1': '0.340', 'Alveolar cells type 2': '0.385', 'Salivary duct cells': '235.0', 'Ductal cells': '0.527', 'Hepatocytes': '0.477', 'Cholangiocytes': '42.0', 'Proximal tubular cells': '0.138', 'Distal tubular cells': '0.0', 'Collecting duct cells': '17.5', 'Mesothelial cells': '0.207', 'Sertoli cells': '0.459', 'Granulosa cells': '9.1', 'Enteroendocrine cells': '11.1', 'Pancreatic endocrine cells': '0.0', 'Leydig cells': '0.597', 'Excitatory neurons': '1.2', 'Inhibitory neurons': '102.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '2.8', 'Bipolar cells': '4.4', 'Horizontal cells': '10.7', 'Astrocytes': '140.0', 'Oligodendrocyte precursor cells': '59.4', 'Oligodendrocytes': '1.3', 'Microglial cells': '38.5', 'Muller glia cells': '77.5', 'Schwann cells': '0.084', 'Spermatogonia': '0.449', 'Spermatocytes': '0.089', 'Early spermatids': '-0.464', 'Late spermatids': '-0.634', 'Oocytes': '0.7', 'Cytotrophoblasts': '278.2', 'Syncytiotrophoblasts': '428.1', 'Extravillous trophoblasts': '34.3', 'Endothelial cells': '15.3', 'Lymphatic endothelial cells': '4.5', 'Cardiomyocytes': '0.263', 'Skeletal myocytes': '0.043', 'Smooth muscle cells': '42.6', 'Adipocytes': '13.0', 'Melanocytes': '0.171', 'Fibroblasts': '110.9', 'Peritubular cells': '0.654', 'Endometrial stromal cells': '56.6', 'Ovarian stromal cells': '23.7', 'Undifferentiated cells': '24.5', 'T-cells': '2.7', 'B-cells': '2.1', 'Plasma cells': '4.5', 'Nk-cells': '0.0', 'Granulocytes': '8.0', 'Monocytes': '0.0', 'Macrophages': '3.8', 'Hofbauer cells': '10.3', 'Kupffer cells': '11.0', 'Dendritic cells': '0.0', 'Langerhans cells': '0.135', 'Erythroid cells': '0.084', 'Adipocytes (Subcutaneous)': '0.200', 'Adipocytes (Visceral)': '0.149', 'Breast glandular cells (progenitors)': '0.322', 'Adipocytes (Breast)': '0.004', 'Colon enterocytes': '-0.029', 'Colon enteroendocrine cells': '0.188', 'Enteric glia cells': '-0.216', 'Mitotic cells (Colon)': '-0.088', 'Mitotic cells (Heart)': '0.181', 'Podocytes': '-0.193', 'Ascending Loop of Henle cells': '0.489', 'Intercalated cells': '-0.040', 'Cholangiocyte': '0.193', 'NK-cells (Liver)': '-0.291', 'Respiratory ciliated cells': '-0.085', 'Mitotic cells (Lung)': '-0.089', 'NK-cells (Lung)': '-0.209', 'B-cells (Lung)': '-0.261', 'Alpha cells': '0.299', 'Beta cells': '0.162', 'Prostate glandular cells': '0.116', 'Prostate basal glandular cells': '0.636', 'Urothelial cells': '0.452', 'Keratinocyte (other)': '0.346', 'Keratinocyte (granular)': '0.197', 'Hair cortex cells': '-0.243', 'Inner root sheath cells': '-0.161', 'Outer root sheath cells': '-0.212', 'Sebaceous gland cells': '-0.107', 'Eccrine sweat gland cells': '-0.170', 'Adipocytes (Skin)': '-0.145', 'Mitotic cells (Skin)': '0.180', 'Parietal cells': '-0.552', 'Chief cells': '-0.576', 'Gastric mucous cells': '-0.519', 'Gastric enteroendocrine cells': '-0.440', 'Mitotic cells (Stomach)': '-0.160', 'Parafollicular cells': '-0.012', 'Thyroid glandular cells': '0.391', 'Mitotic cells (Thyroid)': '-0.068', 'Adrenal cortex cells': '0.614', 'Adrenal medulla cells': '-0.076', 'Mitotic cells (Adrenal gland)': '0.295', 'Minor salivary glandular cells': '0.387', 'Minor salivary gland ductal cells': '0.295', 'Minor salivary gland basal cells': '0.546', 'Mitotic cells (Minor salivary gland)': '0.424', 'Adipocytes (Minor salivary gland)': '0.316', 'Somatotropes': '-0.329', 'Lactotropes': '-0.309', 'Gonadotropes': '-0.009', 'Corticotropes': '-0.035', 'Thyrotropes': '0.052', 'Undifferentiated cells (Pituitary gland)': '0.332', 'Mitotic cells (Spleen)': '-0.282', 'Platelets': '-0.185', 'Erythrocytes': '-0.103', 'Hematopoietic stem cells': '-0.256', 'B-cells (Spleen)': '0.147', 'NK-cells (Spleen)': '0.162', 'Amygdala excitatory': '7.7', 'Cerebellar inhibitory': '1.3', 'Cge interneuron': '314.5', 'Deep-layer corticothalamic and 6b': '3.0', 'Deep-layer intratelencephalic': '1.2', 'Deep-layer near-projecting': '0.9', 'Eccentric medium spiny neuron': '8.6', 'Hippocampal ca1-3': '5.3', 'Hippocampal ca4': '0.5', 'Hippocampal dentate gyrus': '1.0', 'Lamp5-lhx6 and chandelier': '210.8', 'Lower rhombic lip': '0.9', 'Mammillary body': '3.3', 'Medium spiny neuron': '97.6', 'Mge interneuron': '14.2', 'Midbrain-derived inhibitory': '44.0', 'Miscellaneous': '2.7', 'Splatter': '71.9', 'Thalamic excitatory': '5.2', 'Upper rhombic lip': '2.9', 'Upper-layer intratelencephalic': '2.0', 'Astrocyte': '363.8', 'Bergmann glia': '419.5', 'Central nervous system macrophage': '3.4', 'Choroid plexus epithelial cell': '71.2', 'Committed oligodendrocyte precursor': '39.9', 'Ependymal cell': '61.2', 'Oligodendrocyte': '1.9', 'Oligodendrocyte precursor cell': '242.8', 'Endothelial cell': '273.8', 'Pericyte': '236.2', 'Vascular associated smooth muscle cell': '150.2', 'Fibroblast': '213.5', 'Leukocyte': '3.2', 'Basophil': '0.1', 'Eosinophil': '0.0', 'Neutrophil': '0.0', 'Classical monocyte': '0.0', 'Non-classical monocyte': '0.0', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.0', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.0', 'Memory T-reg': '0.0', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Naive T-reg': '0.0'}
1IVO, 1M14, 1M17, 1MOX, 1NQL, 1XKK, 1YY9, 1Z9I, 2EB2, 2EB3, 2GS2, 2GS6, 2GS7, 2ITN, 2ITO, 2ITP, 2ITQ, 2ITT, 2ITU, 2ITV, 2ITW, 2ITX, 2ITY, 2ITZ, 2J5E, 2J5F, 2J6M, 2JIT, 2JIU, 2JIV, 2KS1, 2M0B, 2M20, 2N5S, 2RF9, 2RFD, 2RFE, 2RGP, 3B2U, 3B2V, 3BEL, 3BUO, 3C09, 3G5V, 3G5Y, 3GOP, 3GT8, 3IKA, 3LZB, 3NJP, 3OB2, 3OP0, 3P0Y, 3PFV, 3POZ, 3QWQ, 3UG1, 3UG2, 3VJN, 3VJO, 3VRP, 3VRR, 3W2O, 3W2P, 3W2Q, 3W2R, 3W2S, 3W32, 3W33, 4G5J, 4G5P, 4HJO, 4I1Z, 4I20, 4I21, 4I22, 4I23, 4I24, 4JQ7, 4JQ8, 4JR3, 4JRV, 4KRL, 4KRM, 4KRO, 4KRP, 4LI5, 4LL0, 4LQM, 4LRM, 4R3P, 4R3R, 4R5S, 4RIW, 4RIX, 4RIY, 4RJ4, 4RJ5, 4RJ6, 4RJ7, 4RJ8, 4TKS, 4UIP, 4UV7, 4WD5, 4WKQ, 4WRG, 4ZAU, 4ZJV, 4ZSE, 5C8K, 5C8M, 5C8N, 5CAL, 5CAN, 5CAO, 5CAP, 5CAQ, 5CAS, 5CAU, 5CAV, 5CNN, 5CNO, 5CZH, 5CZI, 5D41, 5EDP, 5EDQ, 5EDR, 5EM5, 5EM6, 5EM7, 5EM8, 5FED, 5FEE, 5FEQ, 5GMP, 5GNK, 5GTY, 5GTZ, 5HCX, 5HCY, 5HCZ, 5HG5, 5HG7, 5HG8, 5HG9, 5HIB, 5HIC, 5J9Y, 5J9Z, 5JEB, 5LV6, 5SX4, 5SX5, 5U8L, 5UG8, 5UG9, 5UGA, 5UGB, 5UGC, 5UWD, 5WB7, 5WB8, 5X26, 5X27, 5X28, 5X2A, 5X2C, 5X2F, 5X2K, 5XDK, 5XDL, 5XGM, 5XGN, 5XWD, 5Y25, 5Y9T, 5YU9, 5ZTO, 5ZWJ, 6ARU, 6B3S, 6D8E, 6DUK, 6JRJ, 6JRK, 6JRX, 6JWL, 6JX0, 6JX4, 6JXT, 6JZ0, 6LUB, 6LUD, 6P1D, 6P1L, 6P8Q, 6S89, 6S8A, 6S9B, 6S9C, 6S9D, 6TFU, 6TFV, 6TFW, 6TFY, 6TFZ, 6TG0, 6TG1, 6V5N, 6V5P, 6V66, 6V6K, 6V6O, 6VH4, 6VHN, 6VHP, 6WA2, 6WAK, 6WXN, 6XL4, 6Z4B, 6Z4D, 7A2A, 7A6I, 7A6J, 7A6K, 7AEI, 7AEM, 7B85, 7ER2, 7JXI, 7JXK, 7JXL, 7JXM, 7JXP, 7JXQ, 7JXW, 7K1H, 7K1I, 7KXZ, 7KY0, 7LEN, 7LFR, 7LFS, 7LG8, 7LGS, 7LTX, 7OM4, 7OXB, 7SI1, 7SYD, 7SYE, 7SZ0, 7SZ1, 7SZ5, 7SZ7, 7T4I, 7T4J, 7TVD, 7U98, 7U99, 7U9A, 7UKV, 7UKW, 7VRA, 7VRE, 7ZYM, 7ZYN, 7ZYP, 7ZYQ, 8A27, 8A2A, 8A2B, 8A2D, 8D73, 8D76, 8DSW, 8EME, 8F1H, 8F1W, 8F1X, 8F1Y, 8F1Z, 8FV3, 8FV4, 8G63, 8GB4, 8H7X, 8HGO, 8HGP, 8HGS, 8HV1, 8HV2, 8HV3, 8HV4, 8HV5, 8HV6, 8HV7, 8HV8, 8HV9, 8HVA, 8HY7, 8PNZ, 8PO0, 8PO1, 8PO2, 8PO3, 8PO4, 8SC7, 8TJL, 8UKV, 8UKW, 8UKX, 8WD4
{'Adipose Tissue': 35.088890365448506, 'Adrenal Gland': 14.852748062015504, 'Bladder': 22.928571428571427, 'Blood': 0.1194507814854682, 'Blood Vessel': 28.20932808988764, 'Brain': 5.374201854655563, 'Breast': 34.68822004357298, 'Cervix Uteri': 32.50157894736842, 'Colon': 18.234400513478818, 'Esophagus': 32.41759792387543, 'Fallopian Tube': 28.95111111111111, 'Heart': 4.491854471544715, 'Kidney': 7.693157303370787, 'Liver': 19.139805309734516, 'Lung': 23.70114532871973, 'Muscle': 8.04806600249066, 'Nerve': 43.8245169628433, 'Ovary': 21.16551666666667, 'Pancreas': 7.779060975609757, 'Pituitary': 5.113484452296819, 'Prostate': 29.221767346938773, 'Salivary Gland': 31.635135802469136, 'Skin': 74.08426202321725, 'Small Intestine': 14.30631550802139, 'Spleen': 7.164622821576764, 'Stomach': 14.548278551532034, 'Testis': 6.923576177285319, 'Thyroid': 25.804085758039815, 'Uterus': 23.39450704225352, 'Vagina': 43.12352564102565}
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SOCS box
substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex
ECS
Yes
IL4, IL4R, EGFR, ELOC, ELOB, CUL2, CUL5
EGFR
null
null
null
null
null
60.818489
0.658134
76.177843
0.433917
258
O75159
P42224
33391546
UbiBrowser
SOCS5
MDKVGKMWNNFKYRCQNLFGHEGGSRSENVDMNSNRCLSVKEKNISIGDSTPQQQSSPLRENIALQLGLSPSKNSSRRNQNCATEIPQIVEISIEKDNDSCVTPGTRLARRDSYSRHAPWGGKKKHSCSTKTQSSLDADKKFGRTRSGLQRRERRYGVSSVHDMDSVSSRTVGSRSLRQRLQDTVGLCFPMRTYSKQSKPLFSNKRKIHLSELMLEKCPFPAGSDLAQKWHLIKQHTAPVSPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYKLGPKLAPGMTEISGDSSAIPQANCDSEEDTTTLCLQSRRQKQRQISGDSHTHVSRQGAWKVHTQIDYIHCLVPDLLQITGNPCYWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYNRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGLLEHYKDPSSCMFFEPLLTISLNRTFPFSLQYICRAVICRCTTYDGIDGLPLPSMLQDFLKEYHYKQKVRVRWLEREPVKAK
Homo sapiens
null
Low tissue specificity
{'Ciliated cells': '6.9', 'Basal respiratory cells': '7.7', 'Club cells': '8.2', 'Ionocytes': '3.3', 'Mucus glandular cells': '14.3', 'Serous glandular cells': '10.5', 'Gastric mucus-secreting cells': '9.4', 'Proximal enterocytes': '4.0', 'Paneth cells': '6.8', 'Distal enterocytes': '8.5', 'Intestinal goblet cells': '6.3', 'Exocrine glandular cells': '-0.552', 'Basal prostatic cells': '13.3', 'Prostatic glandular cells': '12.2', 'Breast glandular cells': '0.426', 'Breast myoepithelial cells': '0.656', 'Glandular and luminal cells': '10.8', 'Secretory cells': '10.6', 'Basal keratinocytes': '10.2', 'Suprabasal keratinocytes': '9.3', 'Basal squamous epithelial cells': '13.1', 'Squamous epithelial cells': '8.1', 'Alveolar cells type 1': '0.015', 'Alveolar cells type 2': '-0.316', 'Salivary duct cells': '16.0', 'Ductal cells': '0.618', 'Hepatocytes': '0.172', 'Cholangiocytes': '19.1', 'Proximal tubular cells': '0.065', 'Distal tubular cells': '12.3', 'Collecting duct cells': '5.8', 'Mesothelial cells': '0.533', 'Sertoli cells': '0.181', 'Granulosa cells': '12.1', 'Enteroendocrine cells': '5.6', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.244', 'Excitatory neurons': '41.9', 'Inhibitory neurons': '49.3', 'Cone photoreceptor cells': '10.2', 'Rod photoreceptor cells': '4.0', 'Bipolar cells': '11.5', 'Horizontal cells': '12.0', 'Astrocytes': '18.0', 'Oligodendrocyte precursor cells': '35.8', 'Oligodendrocytes': '23.7', 'Microglial cells': '17.9', 'Muller glia cells': '8.9', 'Schwann cells': '0.153', 'Spermatogonia': '0.433', 'Spermatocytes': '0.429', 'Early spermatids': '0.141', 'Late spermatids': '-0.193', 'Oocytes': '0.0', 'Cytotrophoblasts': '3.5', 'Syncytiotrophoblasts': '2.8', 'Extravillous trophoblasts': '3.0', 'Endothelial cells': '24.7', 'Lymphatic endothelial cells': '20.1', 'Cardiomyocytes': '0.511', 'Skeletal myocytes': '0.038', 'Smooth muscle cells': '20.8', 'Adipocytes': '17.8', 'Melanocytes': '0.069', 'Fibroblasts': '19.0', 'Peritubular cells': '0.213', 'Endometrial stromal cells': '25.2', 'Ovarian stromal cells': '17.3', 'Undifferentiated cells': '6.2', 'T-cells': '8.1', 'B-cells': '13.7', 'Plasma cells': '6.4', 'Nk-cells': '7.8', 'Granulocytes': '6.7', 'Monocytes': '5.6', 'Macrophages': '9.3', 'Hofbauer cells': '4.5', 'Kupffer cells': '8.0', 'Dendritic cells': '40.6', 'Langerhans cells': '0.131', 'Erythroid cells': '0.141', 'Adipocytes (Subcutaneous)': '-0.439', 'Adipocytes (Visceral)': '-0.392', 'Breast glandular cells (progenitors)': '0.291', 'Adipocytes (Breast)': '-0.562', 'Colon enterocytes': '-0.186', 'Colon enteroendocrine cells': '0.302', 'Enteric glia cells': '0.238', 'Mitotic cells (Colon)': '0.027', 'Mitotic cells (Heart)': '0.520', 'Podocytes': '-0.062', 'Ascending Loop of Henle cells': '0.414', 'Intercalated cells': '-0.062', 'Cholangiocyte': '0.284', 'NK-cells (Liver)': '-0.142', 'Respiratory ciliated cells': '-0.076', 'Mitotic cells (Lung)': '-0.011', 'NK-cells (Lung)': '0.117', 'B-cells (Lung)': '0.037', 'Alpha cells': '0.425', 'Beta cells': '0.262', 'Prostate glandular cells': '-0.457', 'Prostate basal glandular cells': '-0.022', 'Urothelial cells': '0.153', 'Keratinocyte (other)': '-0.122', 'Keratinocyte (granular)': '-0.305', 'Hair cortex cells': '0.193', 'Inner root sheath cells': '0.253', 'Outer root sheath cells': '0.404', 'Sebaceous gland cells': '0.179', 'Eccrine sweat gland cells': '0.283', 'Adipocytes (Skin)': '0.163', 'Mitotic cells (Skin)': '0.314', 'Parietal cells': '-0.649', 'Chief cells': '-0.534', 'Gastric mucous cells': '-0.545', 'Gastric enteroendocrine cells': '-0.405', 'Mitotic cells (Stomach)': '-0.126', 'Parafollicular cells': '0.020', 'Thyroid glandular cells': '0.118', 'Mitotic cells (Thyroid)': '0.166', 'Adrenal cortex cells': '0.587', 'Adrenal medulla cells': '0.034', 'Mitotic cells (Adrenal gland)': '0.379', 'Minor salivary glandular cells': '0.639', 'Minor salivary gland ductal cells': '0.363', 'Minor salivary gland basal cells': '0.072', 'Mitotic cells (Minor salivary gland)': '0.135', 'Adipocytes (Minor salivary gland)': '0.120', 'Somatotropes': '-0.244', 'Lactotropes': '-0.017', 'Gonadotropes': '0.088', 'Corticotropes': '-0.098', 'Thyrotropes': '0.213', 'Undifferentiated cells (Pituitary gland)': '0.399', 'Mitotic cells (Spleen)': '-0.244', 'Platelets': '-0.208', 'Erythrocytes': '-0.113', 'Hematopoietic stem cells': '-0.195', 'B-cells (Spleen)': '0.192', 'NK-cells (Spleen)': '0.169', 'Amygdala excitatory': '0.2', 'Cerebellar inhibitory': '0.2', 'Cge interneuron': '0.4', 'Deep-layer corticothalamic and 6b': '0.3', 'Deep-layer intratelencephalic': '0.1', 'Deep-layer near-projecting': '0.2', 'Eccentric medium spiny neuron': '0.2', 'Hippocampal ca1-3': '0.1', 'Hippocampal ca4': '0.3', 'Hippocampal dentate gyrus': '0.1', 'Lamp5-lhx6 and chandelier': '0.2', 'Lower rhombic lip': '0.2', 'Mammillary body': '0.2', 'Medium spiny neuron': '0.2', 'Mge interneuron': '0.1', 'Midbrain-derived inhibitory': '0.2', 'Miscellaneous': '0.2', 'Splatter': '0.2', 'Thalamic excitatory': '0.1', 'Upper rhombic lip': '1.1', 'Upper-layer intratelencephalic': '0.1', 'Astrocyte': '0.2', 'Bergmann glia': '0.1', 'Central nervous system macrophage': '0.3', 'Choroid plexus epithelial cell': '0.8', 'Committed oligodendrocyte precursor': '0.2', 'Ependymal cell': '0.1', 'Oligodendrocyte': '0.2', 'Oligodendrocyte precursor cell': '0.2', 'Endothelial cell': '0.3', 'Pericyte': '1.0', 'Vascular associated smooth muscle cell': '0.2', 'Fibroblast': '0.1', 'Leukocyte': '0.3', 'Basophil': '17.2', 'Eosinophil': '2.5', 'Neutrophil': '6.9', 'Classical monocyte': '11.8', 'Non-classical monocyte': '9.8', 'Intermediate monocyte': '5.1', 'T-reg': '9.8', 'GdT-cell': '0.9', 'MAIT T-cell': '11.8', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '19.9', 'Memory CD8 T-cell': '0.6', 'Naive CD8 T-cell': '18.3', 'Memory B-cell': '1.8', 'Naive B-cell': '33.1', 'Plasmacytoid DC': '6.9', 'Myeloid DC': '6.2', 'NK-cell': '19.2', 'Total PBMC': '6.0', 'Vd2 gdTCR': '11.3', 'Memory CD4 T-cell Th1\\/Th17': '22.5', 'Memory CD4 T-cell Th17': '16.2', 'Memory CD4 T-cell Th2': '17.7', 'Non-Vd2 gdTCR': '10.2', 'Memory CD4 T-cell Th1': '17.1', 'Memory CD4 T-cell TFH': '14.8', 'Terminal effector memory CD4 T-cell': '7.9', 'Central memory CD8 T-cell': '9.9', 'Effector memory CD8 T-cell': '9.2', 'Terminal effector memory CD8 T-cell': '10.5', 'Non-switched memory B-cell': '10.3', 'Plasmablast': '4.0', 'Switched memory B-cell': '7.5', 'Exhausted memory B-cell': '8.3', 'Progenitor cell': '22.8', 'Memory T-reg': '11.6', 'Naive CD4 T-cell activated': '13.0', 'Naive CD8 T-cell activated': '12.8', 'Naive T-reg': '22.4'}
null
{'Adipose Tissue': 20.25867275747508, 'Adrenal Gland': 12.75481007751938, 'Bladder': 17.15285714285714, 'Blood': 3.2172663078579116, 'Blood Vessel': 23.02793707865169, 'Brain': 11.608470704012111, 'Breast': 20.39918300653595, 'Cervix Uteri': 24.532894736842103, 'Colon': 14.292567394094991, 'Esophagus': 14.687253287197231, 'Fallopian Tube': 20.69, 'Heart': 7.649941114982578, 'Kidney': 6.783460674157303, 'Liver': 4.284588495575221, 'Lung': 17.046, 'Muscle': 6.806485678704857, 'Nerve': 21.98428109854604, 'Ovary': 27.972055555555556, 'Pancreas': 3.755094512195122, 'Pituitary': 11.138766784452296, 'Prostate': 14.877085714285714, 'Salivary Gland': 13.492506172839509, 'Skin': 18.830433388612494, 'Small Intestine': 11.817288770053477, 'Spleen': 13.593684647302904, 'Stomach': 9.558523676880224, 'Testis': 15.72264542936288, 'Thyroid': 16.437451761102604, 'Uterus': 25.595985915492957, 'Vagina': 17.663628205128205}
STAT1
MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKTLQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLNVTELTQNALINDELVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPITKNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEVHPSRLQTTDNLLPMSPEEFDEVSRIVGSVEFDSMMNTV
Homo sapiens
Cytoplasm, Nucleus
Low tissue specificity
{'Ciliated cells': '33.0', 'Basal respiratory cells': '29.9', 'Club cells': '30.5', 'Ionocytes': '23.2', 'Mucus glandular cells': '27.9', 'Serous glandular cells': '21.2', 'Gastric mucus-secreting cells': '52.5', 'Proximal enterocytes': '23.5', 'Paneth cells': '21.5', 'Distal enterocytes': '40.3', 'Intestinal goblet cells': '32.6', 'Exocrine glandular cells': '-0.610', 'Basal prostatic cells': '23.0', 'Prostatic glandular cells': '33.4', 'Breast glandular cells': '0.141', 'Breast myoepithelial cells': '0.192', 'Glandular and luminal cells': '39.8', 'Secretory cells': '23.0', 'Basal keratinocytes': '22.9', 'Suprabasal keratinocytes': '29.6', 'Basal squamous epithelial cells': '23.3', 'Squamous epithelial cells': '29.0', 'Alveolar cells type 1': '0.002', 'Alveolar cells type 2': '-0.161', 'Salivary duct cells': '29.6', 'Ductal cells': '0.627', 'Hepatocytes': '0.456', 'Cholangiocytes': '43.9', 'Proximal tubular cells': '0.272', 'Distal tubular cells': '6.1', 'Collecting duct cells': '48.6', 'Mesothelial cells': '0.200', 'Sertoli cells': '0.388', 'Granulosa cells': '22.6', 'Enteroendocrine cells': '14.4', 'Pancreatic endocrine cells': '20.4', 'Leydig cells': '0.579', 'Excitatory neurons': '8.7', 'Inhibitory neurons': '11.7', 'Cone photoreceptor cells': '8.5', 'Rod photoreceptor cells': '20.5', 'Bipolar cells': '12.7', 'Horizontal cells': '8.2', 'Astrocytes': '13.3', 'Oligodendrocyte precursor cells': '23.6', 'Oligodendrocytes': '11.1', 'Microglial cells': '30.4', 'Muller glia cells': '13.7', 'Schwann cells': '0.142', 'Spermatogonia': '0.656', 'Spermatocytes': '0.350', 'Early spermatids': '-0.206', 'Late spermatids': '-0.552', 'Oocytes': '38.2', 'Cytotrophoblasts': '13.7', 'Syncytiotrophoblasts': '7.9', 'Extravillous trophoblasts': '60.8', 'Endothelial cells': '41.2', 'Lymphatic endothelial cells': '32.6', 'Cardiomyocytes': '0.581', 'Skeletal myocytes': '-0.093', 'Smooth muscle cells': '25.3', 'Adipocytes': '45.1', 'Melanocytes': '0.312', 'Fibroblasts': '35.8', 'Peritubular cells': '0.465', 'Endometrial stromal cells': '45.2', 'Ovarian stromal cells': '22.8', 'Undifferentiated cells': '26.0', 'T-cells': '71.6', 'B-cells': '41.2', 'Plasma cells': '63.4', 'Nk-cells': '48.6', 'Granulocytes': '24.5', 'Monocytes': '66.6', 'Macrophages': '85.4', 'Hofbauer cells': '110.3', 'Kupffer cells': '62.8', 'Dendritic cells': '55.2', 'Langerhans cells': '0.428', 'Erythroid cells': '-0.150', 'Adipocytes (Subcutaneous)': '-0.095', 'Adipocytes (Visceral)': '-0.030', 'Breast glandular cells (progenitors)': '-0.104', 'Adipocytes (Breast)': '-0.179', 'Colon enterocytes': '-0.106', 'Colon enteroendocrine cells': '0.315', 'Enteric glia cells': '-0.017', 'Mitotic cells (Colon)': '0.092', 'Mitotic cells (Heart)': '0.527', 'Podocytes': '-0.027', 'Ascending Loop of Henle cells': '0.270', 'Intercalated cells': '-0.046', 'Cholangiocyte': '0.352', 'NK-cells (Liver)': '-0.226', 'Respiratory ciliated cells': '0.004', 'Mitotic cells (Lung)': '0.154', 'NK-cells (Lung)': '0.392', 'B-cells (Lung)': '0.196', 'Alpha cells': '0.284', 'Beta cells': '0.117', 'Prostate glandular cells': '-0.052', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.152', 'Keratinocyte (other)': '0.437', 'Keratinocyte (granular)': '-0.132', 'Hair cortex cells': '-0.088', 'Inner root sheath cells': '0.005', 'Outer root sheath cells': '0.134', 'Sebaceous gland cells': '-0.020', 'Eccrine sweat gland cells': '-0.077', 'Adipocytes (Skin)': '-0.271', 'Mitotic cells (Skin)': '0.432', 'Parietal cells': '-0.656', 'Chief cells': '-0.540', 'Gastric mucous cells': '-0.247', 'Gastric enteroendocrine cells': '-0.390', 'Mitotic cells (Stomach)': '0.213', 'Parafollicular cells': '0.059', 'Thyroid glandular cells': '0.086', 'Mitotic cells (Thyroid)': '0.340', 'Adrenal cortex cells': '0.571', 'Adrenal medulla cells': '0.055', 'Mitotic cells (Adrenal gland)': '0.314', 'Minor salivary glandular cells': '0.514', 'Minor salivary gland ductal cells': '0.031', 'Minor salivary gland basal cells': '0.313', 'Mitotic cells (Minor salivary gland)': '0.461', 'Adipocytes (Minor salivary gland)': '0.132', 'Somatotropes': '-0.197', 'Lactotropes': '-0.249', 'Gonadotropes': '0.027', 'Corticotropes': '-0.234', 'Thyrotropes': '0.038', 'Undifferentiated cells (Pituitary gland)': '0.396', 'Mitotic cells (Spleen)': '0.129', 'Platelets': '-0.072', 'Erythrocytes': '0.052', 'Hematopoietic stem cells': '-0.067', 'B-cells (Spleen)': '-0.012', 'NK-cells (Spleen)': '0.149', 'Amygdala excitatory': '119.1', 'Cerebellar inhibitory': '120.1', 'Cge interneuron': '113.2', 'Deep-layer corticothalamic and 6b': '124.1', 'Deep-layer intratelencephalic': '163.1', 'Deep-layer near-projecting': '160.0', 'Eccentric medium spiny neuron': '108.4', 'Hippocampal ca1-3': '109.6', 'Hippocampal ca4': '216.9', 'Hippocampal dentate gyrus': '275.8', 'Lamp5-lhx6 and chandelier': '132.2', 'Lower rhombic lip': '350.6', 'Mammillary body': '210.8', 'Medium spiny neuron': '110.4', 'Mge interneuron': '109.0', 'Midbrain-derived inhibitory': '140.9', 'Miscellaneous': '136.8', 'Splatter': '118.3', 'Thalamic excitatory': '149.1', 'Upper rhombic lip': '202.4', 'Upper-layer intratelencephalic': '205.9', 'Astrocyte': '52.6', 'Bergmann glia': '50.2', 'Central nervous system macrophage': '189.1', 'Choroid plexus epithelial cell': '99.1', 'Committed oligodendrocyte precursor': '95.8', 'Ependymal cell': '50.6', 'Oligodendrocyte': '91.8', 'Oligodendrocyte precursor cell': '127.4', 'Endothelial cell': '268.5', 'Pericyte': '130.9', 'Vascular associated smooth muscle cell': '122.1', 'Fibroblast': '113.8', 'Leukocyte': '198.1', 'Basophil': '163.3', 'Eosinophil': '106.0', 'Neutrophil': '861.0', 'Classical monocyte': '157.3', 'Non-classical monocyte': '148.0', 'Intermediate monocyte': '467.5', 'T-reg': '349.9', 'GdT-cell': '51.9', 'MAIT T-cell': '317.8', 'Memory CD4 T-cell': '130.9', 'Naive CD4 T-cell': '202.7', 'Memory CD8 T-cell': '78.4', 'Naive CD8 T-cell': '176.8', 'Memory B-cell': '39.2', 'Naive B-cell': '52.8', 'Plasmacytoid DC': '426.2', 'Myeloid DC': '246.3', 'NK-cell': '109.4', 'Total PBMC': '280.0', 'Vd2 gdTCR': '236.8', 'Memory CD4 T-cell TFH': '160.6', 'Memory CD4 T-cell Th2': '191.1', 'Memory CD4 T-cell Th17': '168.9', 'Memory CD4 T-cell Th1\\/Th17': '198.4', 'Non-Vd2 gdTCR': '195.9', 'Memory CD4 T-cell Th1': '189.6', 'Terminal effector memory CD4 T-cell': '187.9', 'Central memory CD8 T-cell': '359.0', 'Effector memory CD8 T-cell': '359.3', 'Terminal effector memory CD8 T-cell': '203.8', 'Switched memory B-cell': '152.1', 'Plasmablast': '226.0', 'Non-switched memory B-cell': '179.2', 'Exhausted memory B-cell': '137.5', 'Progenitor cell': '152.1', 'Memory T-reg': '227.8', 'Naive CD4 T-cell activated': '627.6', 'Naive CD8 T-cell activated': '808.5', 'Naive T-reg': '170.1'}
1BF5, 1YVL, 2KA6, 3WWT, 7NUF, 8D3F
{'Adipose Tissue': 50.47876245847176, 'Adrenal Gland': 41.741511627906974, 'Bladder': 43.53142857142857, 'Blood': 131.40868891280948, 'Blood Vessel': 52.140711610486896, 'Brain': 22.11497615442846, 'Breast': 43.084945533769066, 'Cervix Uteri': 49.96526315789474, 'Colon': 40.31694480102696, 'Esophagus': 36.73342283737024, 'Fallopian Tube': 37.52222222222222, 'Heart': 17.118678745644598, 'Kidney': 43.45974157303371, 'Liver': 22.487460176991153, 'Lung': 73.2406401384083, 'Muscle': 19.9420099626401, 'Nerve': 50.33907915993538, 'Ovary': 39.602333333333334, 'Pancreas': 13.675429878048782, 'Pituitary': 41.25586572438163, 'Prostate': 44.60583673469388, 'Salivary Gland': 34.556234567901235, 'Skin': 92.85099502487564, 'Small Intestine': 46.47556149732621, 'Spleen': 74.0811203319502, 'Stomach': 31.32184679665738, 'Testis': 28.428947368421053, 'Thyroid': 47.69983154670751, 'Uterus': 42.921619718309856, 'Vagina': 43.66641025641026}
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[0.75, 0.23, 0.13, 0.06, 0.49, 0.46, 0.01, 0.47, 0.69, 0.19, 0.49, 0.68, 0.47, 0.08, 0.27, 0.54, 0.44, 0.05, 0.49, 0.53, 0.33, 0.12, 0.59, 0.76, 0.38, 0.04, 0.16, 0.32, 0.32, 0.0, 0.01, 0.47, 0.37, 0.05, 0.05, 0.69, 0.2, 0.0, 0.3, 0.83, 0.23, 0.5, 0.02, 0.53, 0.44, 0.0, 0.16, 0.82, 0.35, 0.57, 0.56, 0.21, 0.0, 0.35, 0.54, 0.2, 0.0, 0.53, 0.34, 0.0, 0.07, 0.5, 0.25, 0.01, 0.42, 0.46, 0.08, 0.35, 0.53, 0.57, 0.05, 0.34, 0.81, 0.68, 0.74, 0.32, 0.75, 0.69, 0.18, 0.16, 0.48, 0.24, 0.02, 0.62, 0.54, 0.07, 0.2, 0.56, 0.4, 0.02, 0.31, 0.75, 0.64, 0.04, 0.54, 0.97, 0.42, 0.07, 0.23, 0.45, 0.0, 0.0, 0.49, 0.19, 0.01, 0.25, 0.53, 0.08, 0.06, 0.43, 0.35, 0.0, 0.43, 0.44, 0.05, 0.11, 0.53, 0.49, 0.01, 0.6, 0.67, 0.35, 0.53, 0.73, 0.8, 0.41, 0.79, 0.7, 0.53, 0.7, 0.76, 0.69, 0.55, 0.49, 0.45, 0.51, 0.5, 0.41, 0.24, 0.58, 0.52, 0.05, 0.34, 0.5, 0.34, 0.03, 0.59, 0.39, 0.0, 0.51, 0.53, 0.22, 0.03, 0.55, 0.48, 0.05, 0.46, 0.67, 0.16, 0.02, 0.6, 0.43, 0.0, 0.25, 0.55, 0.16, 0.03, 0.42, 0.46, 0.12, 0.41, 0.69, 0.33, 0.16, 0.51, 0.32, 0.21, 0.58, 0.6, 0.59, 0.71, 0.86, 0.8, 0.88, 1.0, 0.9, 0.6, 0.48, 0.77, 0.64, 0.47, 0.4, 0.66, 0.7, 0.32, 0.63, 0.65, 0.46, 0.22, 0.69, 0.62, 0.06, 0.31, 0.57, 0.43, 0.01, 0.1, 0.54, 0.42, 0.01, 0.48, 0.34, 0.01, 0.06, 0.65, 0.26, 0.01, 0.33, 0.45, 0.0, 0.0, 0.4, 0.2, 0.03, 0.4, 0.68, 0.01, 0.0, 0.38, 0.21, 0.0, 0.12, 0.61, 0.49, 0.09, 0.04, 0.53, 0.32, 0.04, 0.42, 0.37, 0.27, 0.08, 0.02, 0.2, 0.33, 0.2, 0.02, 0.25, 0.22, 0.62, 0.95, 0.31, 0.56, 0.67, 0.04, 0.29, 0.38, 0.05, 0.05, 0.51, 0.01, 0.0, 0.13, 0.19, 0.0, 0.0, 0.48, 0.06, 0.02, 0.18, 0.24, 0.05, 0.15, 0.55, 0.07, 0.05, 0.41, 0.22, 0.02, 0.22, 0.36, 0.0, 0.13, 0.83, 0.48, 0.26, 0.59, 0.15, 0.98, 0.68, 0.02, 0.07, 0.04, 0.47, 0.62, 0.26, 0.34, 0.66, 0.59, 0.05, 0.2, 0.51, 0.29, 0.03, 0.34, 0.55, 0.07, 0.06, 0.3, 0.41, 0.0, 0.01, 0.38, 0.19, 0.0, 0.02, 0.03, 0.05, 0.24, 0.5, 0.06, 0.0, 0.14, 0.01, 0.59, 0.76, 0.3, 0.67, 0.44, 0.12, 0.12, 0.01, 0.0, 0.0, 0.25, 0.23, 0.55, 0.21, 0.48, 0.02, 0.15, 0.01, 0.11, 0.0, 0.06, 0.0, 0.0, 0.0, 0.31, 0.09, 0.72, 0.5, 0.01, 0.23, 0.69, 0.55, 0.0, 0.56, 0.0, 0.52, 0.08, 0.31, 0.09, 0.0, 0.27, 0.82, 0.08, 0.67, 0.13, 0.33, 0.89, 0.75, 0.24, 0.58, 0.66, 0.11, 0.13, 0.34, 0.03, 0.44, 0.23, 0.44, 0.69, 0.46, 0.59, 0.3, 0.44, 0.39, 0.0, 0.3, 0.24, 0.29, 0.99, 0.53, 0.98, 0.57, 0.11, 0.03, 0.0, 0.0, 0.0, 0.2, 0.02, 0.62, 0.62, 0.01, 0.28, 0.02, 0.62, 0.27, 0.45, 0.76, 0.67, 0.98, 0.74, 0.91, 0.59, 0.48, 0.86, 0.61, 0.41, 0.63, 0.23, 0.53, 0.35, 0.09, 0.02, 0.1, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.24, 0.05, 0.46, 0.01, 0.6, 0.26, 0.88, 0.85, 0.03, 0.6, 0.0, 0.62, 0.02, 0.46, 0.15, 0.19, 0.01, 0.07, 0.0, 0.0, 0.0, 0.0, 0.01, 0.49, 0.55, 0.46, 0.69, 0.24, 0.12, 0.16, 0.22, 0.0, 0.02, 0.0, 0.0, 0.02, 0.03, 0.0, 0.01, 0.01, 0.04, 0.32, 0.14, 0.67, 0.65, 0.47, 0.35, 0.35, 0.07, 0.35, 0.05, 0.04, 0.5, 0.84, 0.32, 0.43, 0.44, 0.0, 0.54, 0.09, 0.39, 0.34, 0.02, 0.13, 0.52, 0.05, 0.02, 0.17, 0.18, 0.02, 0.0, 0.41, 0.5, 0.18, 0.1, 0.69, 0.33, 0.32, 0.11, 0.42, 0.68, 0.45, 0.02, 0.17, 0.48, 0.11, 0.0, 0.0, 0.41, 0.14, 0.04, 0.3, 0.31, 0.84, 0.9, 0.37, 0.43, 0.58, 0.59, 0.17, 0.57, 0.0, 0.37, 0.03, 0.37, 0.41, 0.01, 0.17, 0.45, 0.44, 0.56, 0.08, 0.71, 0.97, 0.36, 0.81, 0.05, 0.14, 0.0, 0.0, 0.31, 0.01, 0.0, 0.18, 0.12, 0.0, 0.03, 0.36, 0.03, 0.0, 0.44, 0.77, 0.34, 0.0, 0.33, 0.49, 0.02, 0.0, 0.24, 0.5, 0.44, 0.12, 0.04, 0.24, 0.02, 0.04, 0.07, 0.27, 0.6, 0.79, 0.41, 0.06, 0.6, 0.6, 0.24, 0.0, 0.49, 0.87, 0.3, 0.54, 0.49, 0.06, 0.0, 0.0, 0.02, 0.01, 0.12, 0.02, 0.03, 0.23, 0.64, 0.17, 0.68, 0.57, 0.0, 0.0, 0.0, 0.01, 0.0, 0.04, 0.05, 0.02, 0.35, 0.58, 0.48, 0.87, 0.87, 0.85, 0.63, 0.81, 0.18, 0.37, 0.34, 0.19, 0.62, 0.12, 0.92, 0.33, 0.1, 0.2, 0.5, 0.83, 0.41, 0.07, 0.69, 0.73, 0.21, 0.43, 0.01, 0.04, 0.09, 0.04, 0.0, 0.46, 0.38, 0.02, 0.41, 0.15, 0.41, 0.27, 0.89, 0.64, 0.54, 0.51, 0.55, 0.46, 0.17, 0.1, 0.01, 0.54, 0.26, 0.04, 0.36, 0.68, 0.62, 0.38, 0.56, 0.11, 0.62, 0.75, 0.09, 0.0, 0.33, 0.79, 0.21, 0.14, 0.48, 0.91, 0.72, 0.94, 0.94, 0.88, 0.9, 0.93, 0.87, 0.87, 0.95, 0.87, 0.99, 0.77, 0.95, 0.97, 0.87, 0.93, 0.94, 0.94, 0.86, 0.71, 0.88, 0.66, 0.69, 0.56, 0.31, 0.64, 0.39, 0.95, 0.36, 0.75, 0.66, 0.77, 0.64, 0.53, 0.85, 0.71, 0.71, 0.84, 0.84, 0.77, 0.93, 0.92, 0.65, 0.37, 0.76, 0.79, 0.51, 0.55, 0.53, 0.64, 0.4, 0.37, 0.81, 0.77, 0.38, 0.6, 0.97, 0.92, 0.71, 0.53, 0.86, 0.76, 0.82, 0.86, 0.86, 0.9, 0.97]
SOCS box
substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex
ECS
Yes
IL4, IL4R, EGFR, ELOC, ELOB, CUL2, CUL5
EGFR
null
null
null
null
null
60.818489
0.658134
87.709773
0.36164
724
O75382
P04637
33292295
UbiBrowser
TRIM3
MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ
Homo sapiens
Cytoplasm, Early endosome, Golgi apparatus, trans-Golgi network, Cell projection, dendrite
Tissue enhanced (brain)
{'Ciliated cells': '8.6', 'Basal respiratory cells': '2.9', 'Club cells': '6.0', 'Ionocytes': '3.7', 'Mucus glandular cells': '3.6', 'Serous glandular cells': '12.3', 'Gastric mucus-secreting cells': '5.3', 'Proximal enterocytes': '25.8', 'Paneth cells': '5.4', 'Distal enterocytes': '18.9', 'Intestinal goblet cells': '17.5', 'Exocrine glandular cells': '-0.523', 'Basal prostatic cells': '2.4', 'Prostatic glandular cells': '8.0', 'Breast glandular cells': '0.656', 'Breast myoepithelial cells': '0.445', 'Glandular and luminal cells': '6.1', 'Secretory cells': '2.9', 'Basal keratinocytes': '4.6', 'Suprabasal keratinocytes': '3.2', 'Basal squamous epithelial cells': '4.2', 'Squamous epithelial cells': '3.5', 'Alveolar cells type 1': '0.138', 'Alveolar cells type 2': '-0.547', 'Salivary duct cells': '3.9', 'Ductal cells': '0.534', 'Hepatocytes': '0.259', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.216', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.436', 'Sertoli cells': '0.330', 'Granulosa cells': '2.6', 'Enteroendocrine cells': '6.9', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.450', 'Excitatory neurons': '12.7', 'Inhibitory neurons': '11.7', 'Cone photoreceptor cells': '11.9', 'Rod photoreceptor cells': '9.4', 'Bipolar cells': '9.4', 'Horizontal cells': '6.3', 'Astrocytes': '9.3', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '9.4', 'Microglial cells': '10.7', 'Muller glia cells': '2.1', 'Schwann cells': '0.335', 'Spermatogonia': '0.359', 'Spermatocytes': '0.030', 'Early spermatids': '-0.540', 'Late spermatids': '-0.543', 'Oocytes': '11.0', 'Cytotrophoblasts': '1.7', 'Syncytiotrophoblasts': '1.1', 'Extravillous trophoblasts': '2.2', 'Endothelial cells': '6.7', 'Lymphatic endothelial cells': '9.3', 'Cardiomyocytes': '0.422', 'Skeletal myocytes': '-0.193', 'Smooth muscle cells': '9.6', 'Adipocytes': '8.0', 'Melanocytes': '-0.172', 'Fibroblasts': '6.6', 'Peritubular cells': '0.545', 'Endometrial stromal cells': '4.3', 'Ovarian stromal cells': '4.6', 'Undifferentiated cells': '4.8', 'T-cells': '3.6', 'B-cells': '2.5', 'Plasma cells': '1.1', 'Nk-cells': '4.0', 'Granulocytes': '2.1', 'Monocytes': '2.0', 'Macrophages': '4.0', 'Hofbauer cells': '4.7', 'Kupffer cells': '1.0', 'Dendritic cells': '0.8', 'Langerhans cells': '-0.051', 'Erythroid cells': '-0.017', 'Adipocytes (Subcutaneous)': '-0.432', 'Adipocytes (Visceral)': '-0.417', 'Breast glandular cells (progenitors)': '0.413', 'Adipocytes (Breast)': '-0.486', 'Colon enterocytes': '-0.078', 'Colon enteroendocrine cells': '0.167', 'Enteric glia cells': '0.327', 'Mitotic cells (Colon)': '-0.142', 'Mitotic cells (Heart)': '0.491', 'Podocytes': '-0.134', 'Ascending Loop of Henle cells': '0.378', 'Intercalated cells': '-0.125', 'Cholangiocyte': '0.253', 'NK-cells (Liver)': '-0.136', 'Respiratory ciliated cells': '0.184', 'Mitotic cells (Lung)': '-0.141', 'NK-cells (Lung)': '0.372', 'B-cells (Lung)': '0.116', 'Alpha cells': '0.484', 'Beta cells': '0.359', 'Prostate glandular cells': '0.186', 'Prostate basal glandular cells': '0.112', 'Urothelial cells': '-0.104', 'Keratinocyte (other)': '-0.341', 'Keratinocyte (granular)': '-0.270', 'Hair cortex cells': '0.154', 'Inner root sheath cells': '0.093', 'Outer root sheath cells': '0.280', 'Sebaceous gland cells': '0.020', 'Eccrine sweat gland cells': '0.405', 'Adipocytes (Skin)': '0.264', 'Mitotic cells (Skin)': '0.019', 'Parietal cells': '-0.612', 'Chief cells': '-0.460', 'Gastric mucous cells': '-0.476', 'Gastric enteroendocrine cells': '-0.327', 'Mitotic cells (Stomach)': '-0.171', 'Parafollicular cells': '0.022', 'Thyroid glandular cells': '-0.034', 'Mitotic cells (Thyroid)': '0.046', 'Adrenal cortex cells': '0.159', 'Adrenal medulla cells': '0.213', 'Mitotic cells (Adrenal gland)': '0.107', 'Minor salivary glandular cells': '0.442', 'Minor salivary gland ductal cells': '0.351', 'Minor salivary gland basal cells': '-0.273', 'Mitotic cells (Minor salivary gland)': '-0.421', 'Adipocytes (Minor salivary gland)': '-0.075', 'Somatotropes': '-0.278', 'Lactotropes': '-0.011', 'Gonadotropes': '0.214', 'Corticotropes': '-0.086', 'Thyrotropes': '0.219', 'Undifferentiated cells (Pituitary gland)': '0.333', 'Mitotic cells (Spleen)': '-0.397', 'Platelets': '-0.171', 'Erythrocytes': '-0.086', 'Hematopoietic stem cells': '-0.354', 'B-cells (Spleen)': '0.226', 'NK-cells (Spleen)': '0.281', 'Amygdala excitatory': '20.5', 'Cerebellar inhibitory': '12.7', 'Cge interneuron': '20.3', 'Deep-layer corticothalamic and 6b': '25.9', 'Deep-layer intratelencephalic': '23.3', 'Deep-layer near-projecting': '21.2', 'Eccentric medium spiny neuron': '16.6', 'Hippocampal ca1-3': '21.1', 'Hippocampal ca4': '16.6', 'Hippocampal dentate gyrus': '12.7', 'Lamp5-lhx6 and chandelier': '21.0', 'Lower rhombic lip': '21.7', 'Mammillary body': '15.4', 'Medium spiny neuron': '12.8', 'Mge interneuron': '19.3', 'Midbrain-derived inhibitory': '34.0', 'Miscellaneous': '21.1', 'Splatter': '16.7', 'Thalamic excitatory': '20.7', 'Upper rhombic lip': '31.4', 'Upper-layer intratelencephalic': '22.1', 'Astrocyte': '10.1', 'Bergmann glia': '9.2', 'Central nervous system macrophage': '9.5', 'Choroid plexus epithelial cell': '3.7', 'Committed oligodendrocyte precursor': '12.6', 'Ependymal cell': '5.2', 'Oligodendrocyte': '15.5', 'Oligodendrocyte precursor cell': '11.2', 'Endothelial cell': '14.0', 'Pericyte': '16.6', 'Vascular associated smooth muscle cell': '13.9', 'Fibroblast': '13.5', 'Leukocyte': '6.7', 'Basophil': '6.7', 'Eosinophil': '0.5', 'Neutrophil': '2.1', 'Classical monocyte': '13.4', 'Non-classical monocyte': '7.6', 'Intermediate monocyte': '4.5', 'T-reg': '2.1', 'GdT-cell': '0.5', 'MAIT T-cell': '4.4', 'Memory CD4 T-cell': '0.4', 'Naive CD4 T-cell': '10.2', 'Memory CD8 T-cell': '0.4', 'Naive CD8 T-cell': '9.3', 'Memory B-cell': '0.1', 'Naive B-cell': '7.4', 'Plasmacytoid DC': '1.4', 'Myeloid DC': '6.2', 'NK-cell': '18.4', 'Total PBMC': '2.7', 'Vd2 gdTCR': '4.2', 'Memory CD4 T-cell Th1\\/Th17': '11.0', 'Memory CD4 T-cell Th17': '13.4', 'Memory CD4 T-cell Th2': '12.3', 'Non-Vd2 gdTCR': '6.9', 'Memory CD4 T-cell Th1': '12.9', 'Memory CD4 T-cell TFH': '13.6', 'Terminal effector memory CD4 T-cell': '9.2', 'Central memory CD8 T-cell': '1.1', 'Effector memory CD8 T-cell': '3.7', 'Terminal effector memory CD8 T-cell': '3.4', 'Non-switched memory B-cell': '1.9', 'Plasmablast': '0.3', 'Switched memory B-cell': '2.0', 'Exhausted memory B-cell': '1.7', 'Progenitor cell': '3.9', 'Memory T-reg': '14.2', 'Naive CD4 T-cell activated': '4.1', 'Naive CD8 T-cell activated': '4.7', 'Naive T-reg': '9.9'}
7O0B, 7QRW, 8AMR
{'Adipose Tissue': 15.995526578073092, 'Adrenal Gland': 6.926104651162791, 'Bladder': 20.767619047619046, 'Blood': 3.0819308934337997, 'Blood Vessel': 26.789330337078653, 'Brain': 28.75113349735049, 'Breast': 21.02602396514161, 'Cervix Uteri': 25.929263157894734, 'Colon': 20.822940949935816, 'Esophagus': 14.713867820069204, 'Fallopian Tube': 23.26555555555556, 'Heart': 6.1021161440185825, 'Kidney': 7.885269662921348, 'Liver': 5.314053097345133, 'Lung': 21.31820242214533, 'Muscle': 7.669161892901618, 'Nerve': 31.077915993537964, 'Ovary': 19.07497777777778, 'Pancreas': 4.9334847560975605, 'Pituitary': 12.569254416961131, 'Prostate': 21.015779591836736, 'Salivary Gland': 14.29141975308642, 'Skin': 13.737883360972912, 'Small Intestine': 21.71072192513369, 'Spleen': 12.217771784232363, 'Stomach': 14.288077994428969, 'Testis': 8.707102493074792, 'Thyroid': 16.040655436447167, 'Uterus': 29.908732394366197, 'Vagina': 19.93869871794872}
TP53
MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD
Homo sapiens
Cytoplasm, Nucleus, Nucleus, PML body, Endoplasmic reticulum, Mitochondrion matrix, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Nucleus, Cytoplasm, Cytoplasm
Low tissue specificity
{'Ciliated cells': '9.7', 'Basal respiratory cells': '24.5', 'Club cells': '17.3', 'Ionocytes': '15.5', 'Mucus glandular cells': '17.4', 'Serous glandular cells': '17.1', 'Gastric mucus-secreting cells': '11.2', 'Proximal enterocytes': '10.3', 'Paneth cells': '26.0', 'Distal enterocytes': '18.1', 'Intestinal goblet cells': '35.3', 'Exocrine glandular cells': '-0.708', 'Basal prostatic cells': '22.3', 'Prostatic glandular cells': '18.3', 'Breast glandular cells': '0.568', 'Breast myoepithelial cells': '0.559', 'Glandular and luminal cells': '21.5', 'Secretory cells': '38.8', 'Basal keratinocytes': '34.6', 'Suprabasal keratinocytes': '32.5', 'Basal squamous epithelial cells': '31.0', 'Squamous epithelial cells': '34.2', 'Alveolar cells type 1': '-0.172', 'Alveolar cells type 2': '0.210', 'Salivary duct cells': '19.8', 'Ductal cells': '0.627', 'Hepatocytes': '0.473', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.199', 'Distal tubular cells': '15.4', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.355', 'Sertoli cells': '0.685', 'Granulosa cells': '20.0', 'Enteroendocrine cells': '29.3', 'Pancreatic endocrine cells': '20.4', 'Leydig cells': '0.655', 'Excitatory neurons': '2.0', 'Inhibitory neurons': '3.0', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '7.6', 'Bipolar cells': '5.3', 'Horizontal cells': '2.5', 'Astrocytes': '15.5', 'Oligodendrocyte precursor cells': '8.5', 'Oligodendrocytes': '7.4', 'Microglial cells': '7.2', 'Muller glia cells': '9.8', 'Schwann cells': '0.115', 'Spermatogonia': '0.447', 'Spermatocytes': '0.010', 'Early spermatids': '-0.537', 'Late spermatids': '-0.647', 'Oocytes': '4.4', 'Cytotrophoblasts': '39.7', 'Syncytiotrophoblasts': '20.4', 'Extravillous trophoblasts': '40.6', 'Endothelial cells': '26.1', 'Lymphatic endothelial cells': '20.1', 'Cardiomyocytes': '0.292', 'Skeletal myocytes': '-0.271', 'Smooth muscle cells': '18.8', 'Adipocytes': '22.1', 'Melanocytes': '0.378', 'Fibroblasts': '15.8', 'Peritubular cells': '0.544', 'Endometrial stromal cells': '28.3', 'Ovarian stromal cells': '20.5', 'Undifferentiated cells': '65.7', 'T-cells': '20.5', 'B-cells': '28.3', 'Plasma cells': '12.2', 'Nk-cells': '24.3', 'Granulocytes': '15.2', 'Monocytes': '23.2', 'Macrophages': '22.3', 'Hofbauer cells': '25.4', 'Kupffer cells': '28.1', 'Dendritic cells': '37.3', 'Langerhans cells': '0.416', 'Erythroid cells': '-0.142', 'Adipocytes (Subcutaneous)': '-0.285', 'Adipocytes (Visceral)': '-0.318', 'Breast glandular cells (progenitors)': '0.579', 'Adipocytes (Breast)': '-0.562', 'Colon enterocytes': '0.130', 'Colon enteroendocrine cells': '0.043', 'Enteric glia cells': '-0.338', 'Mitotic cells (Colon)': '0.199', 'Mitotic cells (Heart)': '0.516', 'Podocytes': '-0.175', 'Ascending Loop of Henle cells': '0.423', 'Intercalated cells': '-0.083', 'Cholangiocyte': '0.275', 'NK-cells (Liver)': '-0.251', 'Respiratory ciliated cells': '-0.071', 'Mitotic cells (Lung)': '0.244', 'NK-cells (Lung)': '-0.182', 'B-cells (Lung)': '-0.197', 'Alpha cells': '0.374', 'Beta cells': '0.172', 'Prostate glandular cells': '0.093', 'Prostate basal glandular cells': '0.400', 'Urothelial cells': '0.283', 'Keratinocyte (other)': '0.597', 'Keratinocyte (granular)': '-0.067', 'Hair cortex cells': '-0.039', 'Inner root sheath cells': '-0.007', 'Outer root sheath cells': '0.116', 'Sebaceous gland cells': '0.053', 'Eccrine sweat gland cells': '-0.248', 'Adipocytes (Skin)': '-0.383', 'Mitotic cells (Skin)': '0.447', 'Parietal cells': '-0.422', 'Chief cells': '-0.314', 'Gastric mucous cells': '-0.080', 'Gastric enteroendocrine cells': '-0.187', 'Mitotic cells (Stomach)': '0.363', 'Parafollicular cells': '0.045', 'Thyroid glandular cells': '0.117', 'Mitotic cells (Thyroid)': '0.058', 'Adrenal cortex cells': '0.509', 'Adrenal medulla cells': '-0.014', 'Mitotic cells (Adrenal gland)': '0.423', 'Minor salivary glandular cells': '0.553', 'Minor salivary gland ductal cells': '-0.053', 'Minor salivary gland basal cells': '0.505', 'Mitotic cells (Minor salivary gland)': '0.616', 'Adipocytes (Minor salivary gland)': '0.268', 'Somatotropes': '-0.284', 'Lactotropes': '-0.362', 'Gonadotropes': '0.004', 'Corticotropes': '-0.175', 'Thyrotropes': '-0.048', 'Undifferentiated cells (Pituitary gland)': '0.537', 'Mitotic cells (Spleen)': '-0.087', 'Platelets': '0.030', 'Erythrocytes': '-0.192', 'Hematopoietic stem cells': '-0.087', 'B-cells (Spleen)': '0.501', 'NK-cells (Spleen)': '0.140', 'Amygdala excitatory': '3.7', 'Cerebellar inhibitory': '6.2', 'Cge interneuron': '5.2', 'Deep-layer corticothalamic and 6b': '3.9', 'Deep-layer intratelencephalic': '4.3', 'Deep-layer near-projecting': '3.7', 'Eccentric medium spiny neuron': '3.7', 'Hippocampal ca1-3': '5.1', 'Hippocampal ca4': '5.7', 'Hippocampal dentate gyrus': '3.9', 'Lamp5-lhx6 and chandelier': '6.2', 'Lower rhombic lip': '4.4', 'Mammillary body': '4.7', 'Medium spiny neuron': '3.4', 'Mge interneuron': '5.6', 'Midbrain-derived inhibitory': '3.2', 'Miscellaneous': '4.1', 'Splatter': '4.9', 'Thalamic excitatory': '4.3', 'Upper rhombic lip': '3.5', 'Upper-layer intratelencephalic': '3.3', 'Astrocyte': '44.6', 'Bergmann glia': '33.2', 'Central nervous system macrophage': '29.3', 'Choroid plexus epithelial cell': '15.7', 'Committed oligodendrocyte precursor': '19.1', 'Ependymal cell': '8.2', 'Oligodendrocyte': '14.6', 'Oligodendrocyte precursor cell': '13.8', 'Endothelial cell': '19.0', 'Pericyte': '18.3', 'Vascular associated smooth muscle cell': '13.0', 'Fibroblast': '21.1', 'Leukocyte': '28.2', 'Basophil': '11.5', 'Eosinophil': '3.4', 'Neutrophil': '7.2', 'Classical monocyte': '18.8', 'Non-classical monocyte': '38.8', 'Intermediate monocyte': '57.9', 'T-reg': '41.2', 'GdT-cell': '13.0', 'MAIT T-cell': '47.7', 'Memory CD4 T-cell': '13.4', 'Naive CD4 T-cell': '35.3', 'Memory CD8 T-cell': '14.6', 'Naive CD8 T-cell': '33.9', 'Memory B-cell': '21.7', 'Naive B-cell': '39.1', 'Plasmacytoid DC': '77.7', 'Myeloid DC': '108.7', 'NK-cell': '34.9', 'Total PBMC': '42.1', 'Vd2 gdTCR': '50.5', 'Memory CD4 T-cell Th1\\/Th17': '29.2', 'Memory CD4 T-cell Th17': '31.4', 'Memory CD4 T-cell Th2': '32.4', 'Non-Vd2 gdTCR': '44.9', 'Memory CD4 T-cell Th1': '33.4', 'Memory CD4 T-cell TFH': '41.7', 'Terminal effector memory CD4 T-cell': '37.7', 'Central memory CD8 T-cell': '50.6', 'Effector memory CD8 T-cell': '44.8', 'Terminal effector memory CD8 T-cell': '36.8', 'Non-switched memory B-cell': '67.9', 'Plasmablast': '55.7', 'Switched memory B-cell': '69.3', 'Exhausted memory B-cell': '61.4', 'Progenitor cell': '66.7', 'Memory T-reg': '44.7', 'Naive CD4 T-cell activated': '50.4', 'Naive CD8 T-cell activated': '57.4', 'Naive T-reg': '53.9'}
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{'Adipose Tissue': 20.93964202657807, 'Adrenal Gland': 12.759116279069769, 'Bladder': 25.428571428571427, 'Blood': 21.223136490850376, 'Blood Vessel': 20.479797752808988, 'Brain': 3.727845155185465, 'Breast': 25.228115468409587, 'Cervix Uteri': 29.012105263157896, 'Colon': 16.55034788189987, 'Esophagus': 18.857026297577853, 'Fallopian Tube': 26.596666666666668, 'Heart': 5.263052032520325, 'Kidney': 8.437685393258427, 'Liver': 7.446044247787611, 'Lung': 17.59700346020761, 'Muscle': 6.559450809464508, 'Nerve': 24.945169628432957, 'Ovary': 33.661611111111114, 'Pancreas': 7.645850609756097, 'Pituitary': 9.726681978798586, 'Prostate': 21.03564081632653, 'Salivary Gland': 20.003833333333333, 'Skin': 35.77461967938087, 'Small Intestine': 20.144877005347595, 'Spleen': 26.64536514522822, 'Stomach': 13.411871866295265, 'Testis': 15.452573407202216, 'Thyroid': 20.29615007656968, 'Uterus': 32.07880281690141, 'Vagina': 25.855192307692302}
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[40.87, 42.37, 37.34, 41.12, 36.28, 39.25, 37.74, 35.43, 38.07, 38.7, 46.99, 46.82, 45.44, 48.46, 60.33, 52.54, 56.28, 62.33, 59.05, 65.74, 66.79, 68.31, 67.62, 70.23, 70.74, 58.72, 62.81, 57.24, 45.04, 38.19, 39.44, 33.54, 35.19, 33.9, 34.62, 34.62, 30.98, 36.77, 36.14, 33.82, 35.11, 37.0, 37.65, 35.35, 40.22, 36.67, 36.17, 45.38, 43.43, 45.47, 43.32, 41.86, 42.46, 37.48, 40.19, 39.08, 41.84, 41.57, 40.13, 45.33, 44.83, 40.61, 46.68, 41.99, 40.66, 48.37, 45.35, 40.78, 42.77, 44.99, 51.82, 46.66, 45.09, 49.92, 48.07, 49.39, 51.88, 47.88, 49.9, 52.31, 51.53, 55.41, 52.55, 57.59, 53.56, 48.88, 50.01, 52.51, 44.8, 58.58, 57.48, 58.84, 61.16, 64.5, 60.79, 87.3, 91.9, 93.67, 94.32, 93.13, 95.4, 97.18, 97.88, 97.4, 96.19, 96.67, 97.18, 96.81, 98.03, 97.53, 97.93, 96.29, 97.14, 93.15, 88.03, 89.09, 89.98, 92.31, 92.8, 87.74, 91.82, 95.69, 96.78, 97.3, 97.82, 97.98, 97.12, 95.58, 94.67, 95.91, 97.14, 98.1, 98.31, 98.5, 98.18, 98.01, 96.93, 95.45, 96.64, 97.02, 97.5, 97.23, 98.15, 97.6, 97.97, 97.91, 97.61, 96.64, 95.78, 95.83, 96.75, 96.44, 96.11, 96.41, 98.18, 98.07, 98.41, 98.38, 98.48, 98.0, 97.91, 97.3, 97.85, 96.96, 94.5, 92.99, 93.51, 93.35, 93.17, 93.17, 94.24, 95.19, 96.58, 94.61, 96.38, 96.44, 95.0, 94.74, 94.02, 92.98, 91.38, 83.44, 68.18, 69.78, 67.73, 69.29, 75.66, 81.41, 90.73, 92.74, 93.45, 93.42, 95.71, 97.01, 97.65, 96.53, 96.51, 92.67, 89.17, 89.46, 90.95, 94.56, 95.63, 96.0, 96.57, 95.27, 94.47, 93.19, 90.89, 90.66, 92.07, 93.48, 95.39, 96.54, 97.45, 97.61, 97.79, 97.71, 97.66, 97.45, 96.01, 95.46, 95.62, 94.54, 94.69, 93.84, 94.06, 93.35, 95.04, 96.63, 96.93, 97.67, 97.32, 97.96, 96.97, 97.83, 96.66, 97.08, 98.03, 98.05, 97.54, 97.24, 96.47, 93.39, 94.32, 96.83, 97.3, 96.76, 97.44, 97.88, 98.33, 98.19, 98.49, 98.41, 98.58, 98.54, 98.43, 98.32, 97.12, 96.11, 95.91, 94.03, 96.55, 97.67, 98.11, 97.99, 98.54, 98.08, 98.0, 98.3, 98.38, 98.62, 98.43, 98.6, 97.98, 97.23, 96.83, 97.83, 97.02, 96.53, 97.06, 97.21, 95.97, 95.98, 96.28, 95.87, 95.03, 93.39, 91.91, 91.08, 89.16, 80.7, 66.19, 54.71, 45.53, 49.48, 47.5, 39.17, 48.58, 45.3, 47.53, 39.52, 44.86, 46.58, 47.5, 43.75, 40.22, 48.29, 42.5, 44.9, 43.14, 44.26, 44.27, 42.59, 38.35, 47.81, 48.47, 45.67, 49.67, 50.03, 50.54, 50.85, 53.27, 70.22, 79.25, 87.32, 88.32, 91.36, 93.43, 94.53, 95.74, 96.13, 96.15, 94.94, 95.04, 95.21, 94.23, 96.83, 95.75, 95.17, 96.92, 94.59, 95.14, 95.57, 95.21, 91.98, 93.68, 92.45, 88.86, 86.47, 88.93, 87.81, 82.92, 80.11, 79.44, 65.74, 59.35, 45.38, 48.65, 36.69, 34.67, 38.46, 39.41, 38.67, 38.97, 38.67, 43.72, 39.99, 39.85, 43.24, 38.88, 46.62, 42.32, 36.07, 39.71, 36.23, 42.3, 45.0, 45.17, 44.05, 45.61, 46.83, 37.81, 49.59, 48.5, 45.24, 50.91, 45.34, 59.46, 52.4, 43.13, 50.82, 47.63]
[1.0, 0.99, 0.99, 0.97, 0.97, 0.94, 0.91, 0.96, 0.91, 0.91, 0.98, 0.88, 0.89, 0.83, 0.48, 0.91, 0.84, 0.44, 0.6, 0.59, 0.57, 0.51, 0.64, 0.76, 0.78, 0.61, 0.83, 0.92, 0.92, 0.96, 0.97, 0.94, 1.0, 0.95, 0.95, 0.95, 0.94, 0.94, 1.0, 0.99, 0.99, 1.0, 0.9, 1.0, 0.89, 0.73, 0.92, 0.8, 0.94, 0.85, 0.9, 0.93, 0.97, 0.92, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 0.97, 0.98, 0.93, 0.95, 0.98, 0.94, 0.92, 0.93, 0.92, 0.9, 0.94, 0.89, 0.91, 0.95, 0.89, 0.95, 0.87, 0.67, 0.92, 0.72, 0.51, 0.65, 0.03, 0.88, 0.47, 0.46, 0.32, 0.41, 0.44, 0.75, 0.58, 0.45, 0.54, 0.36, 0.88, 0.21, 0.08, 0.0, 0.41, 0.17, 0.16, 0.14, 0.49, 0.89, 0.38, 0.59, 0.27, 0.53, 0.82, 0.8, 0.17, 0.37, 0.18, 0.01, 0.17, 0.0, 0.56, 0.7, 0.25, 0.38, 0.07, 0.01, 0.0, 0.0, 0.24, 0.37, 0.44, 0.46, 0.38, 0.0, 0.22, 0.0, 0.18, 0.04, 0.24, 0.2, 0.66, 0.47, 0.74, 0.09, 0.52, 0.94, 0.51, 0.06, 0.24, 0.02, 0.18, 0.01, 0.15, 0.1, 0.0, 0.01, 0.5, 0.41, 0.73, 0.88, 0.19, 0.17, 0.34, 0.32, 0.12, 0.05, 0.21, 0.04, 0.04, 0.41, 0.82, 0.17, 0.37, 0.84, 0.38, 0.82, 0.54, 0.48, 0.7, 0.75, 0.59, 0.08, 0.27, 0.37, 0.28, 0.01, 0.03, 0.08, 0.04, 0.12, 0.47, 0.95, 0.2, 0.8, 0.53, 0.17, 0.47, 0.19, 0.38, 0.45, 0.39, 0.88, 0.85, 0.22, 0.4, 0.03, 0.13, 0.06, 0.01, 0.01, 0.02, 0.31, 0.14, 0.49, 0.69, 0.35, 0.84, 0.98, 0.99, 0.48, 0.59, 0.13, 0.13, 0.45, 0.09, 0.39, 0.01, 0.11, 0.0, 0.1, 0.0, 0.24, 0.09, 0.55, 0.13, 0.8, 0.66, 0.09, 0.0, 0.54, 0.8, 0.18, 0.3, 0.01, 0.11, 0.01, 0.04, 0.0, 0.12, 0.0, 0.09, 0.27, 0.69, 0.76, 0.52, 0.53, 0.4, 0.17, 0.0, 0.15, 0.19, 0.12, 0.0, 0.09, 0.02, 0.35, 0.03, 0.08, 0.71, 0.43, 0.0, 0.01, 0.63, 0.13, 0.11, 0.43, 0.34, 0.23, 0.24, 0.21, 0.46, 0.45, 0.51, 0.35, 0.63, 0.77, 0.55, 0.5, 0.77, 0.87, 0.9, 0.91, 0.94, 0.95, 0.84, 0.98, 0.9, 0.99, 0.98, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.93, 0.96, 0.92, 0.91, 0.93, 0.89, 0.93, 0.92, 0.7, 0.69, 0.78, 0.47, 0.54, 0.67, 0.68, 0.9, 0.69, 0.93, 0.33, 0.82, 0.56, 0.78, 0.78, 0.5, 0.5, 0.38, 0.62, 0.46, 0.41, 0.69, 0.56, 0.49, 0.53, 0.52, 0.51, 0.53, 0.58, 0.67, 0.6, 0.22, 0.62, 0.59, 0.67, 0.6, 0.78, 0.81, 0.94, 0.88, 0.83, 0.94, 0.86, 0.87, 0.81, 0.81, 0.82, 0.91, 0.86, 0.94, 0.95, 1.0, 0.97, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.84, 0.97, 0.84, 0.84, 0.9, 0.83, 0.98, 1.0, 1.0, 1.0, 1.0]
RING finger
Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3
CART
null
TRIM2, MYO5B,ACTN4, ZFYVE28, KIF21B , HGS TRIM3
GKAP, CDKN1A, TLR3
63
null
null
Homooligomer
null
83.98836
0.421976
74.332875
0.582494
1,067
O75382
Q14457
32021240
UbiBrowser
TRIM3
MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ
Homo sapiens
Cytoplasm, Early endosome, Golgi apparatus, trans-Golgi network, Cell projection, dendrite
Tissue enhanced (brain)
{'Ciliated cells': '8.6', 'Basal respiratory cells': '2.9', 'Club cells': '6.0', 'Ionocytes': '3.7', 'Mucus glandular cells': '3.6', 'Serous glandular cells': '12.3', 'Gastric mucus-secreting cells': '5.3', 'Proximal enterocytes': '25.8', 'Paneth cells': '5.4', 'Distal enterocytes': '18.9', 'Intestinal goblet cells': '17.5', 'Exocrine glandular cells': '-0.523', 'Basal prostatic cells': '2.4', 'Prostatic glandular cells': '8.0', 'Breast glandular cells': '0.656', 'Breast myoepithelial cells': '0.445', 'Glandular and luminal cells': '6.1', 'Secretory cells': '2.9', 'Basal keratinocytes': '4.6', 'Suprabasal keratinocytes': '3.2', 'Basal squamous epithelial cells': '4.2', 'Squamous epithelial cells': '3.5', 'Alveolar cells type 1': '0.138', 'Alveolar cells type 2': '-0.547', 'Salivary duct cells': '3.9', 'Ductal cells': '0.534', 'Hepatocytes': '0.259', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.216', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.436', 'Sertoli cells': '0.330', 'Granulosa cells': '2.6', 'Enteroendocrine cells': '6.9', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.450', 'Excitatory neurons': '12.7', 'Inhibitory neurons': '11.7', 'Cone photoreceptor cells': '11.9', 'Rod photoreceptor cells': '9.4', 'Bipolar cells': '9.4', 'Horizontal cells': '6.3', 'Astrocytes': '9.3', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '9.4', 'Microglial cells': '10.7', 'Muller glia cells': '2.1', 'Schwann cells': '0.335', 'Spermatogonia': '0.359', 'Spermatocytes': '0.030', 'Early spermatids': '-0.540', 'Late spermatids': '-0.543', 'Oocytes': '11.0', 'Cytotrophoblasts': '1.7', 'Syncytiotrophoblasts': '1.1', 'Extravillous trophoblasts': '2.2', 'Endothelial cells': '6.7', 'Lymphatic endothelial cells': '9.3', 'Cardiomyocytes': '0.422', 'Skeletal myocytes': '-0.193', 'Smooth muscle cells': '9.6', 'Adipocytes': '8.0', 'Melanocytes': '-0.172', 'Fibroblasts': '6.6', 'Peritubular cells': '0.545', 'Endometrial stromal cells': '4.3', 'Ovarian stromal cells': '4.6', 'Undifferentiated cells': '4.8', 'T-cells': '3.6', 'B-cells': '2.5', 'Plasma cells': '1.1', 'Nk-cells': '4.0', 'Granulocytes': '2.1', 'Monocytes': '2.0', 'Macrophages': '4.0', 'Hofbauer cells': '4.7', 'Kupffer cells': '1.0', 'Dendritic cells': '0.8', 'Langerhans cells': '-0.051', 'Erythroid cells': '-0.017', 'Adipocytes (Subcutaneous)': '-0.432', 'Adipocytes (Visceral)': '-0.417', 'Breast glandular cells (progenitors)': '0.413', 'Adipocytes (Breast)': '-0.486', 'Colon enterocytes': '-0.078', 'Colon enteroendocrine cells': '0.167', 'Enteric glia cells': '0.327', 'Mitotic cells (Colon)': '-0.142', 'Mitotic cells (Heart)': '0.491', 'Podocytes': '-0.134', 'Ascending Loop of Henle cells': '0.378', 'Intercalated cells': '-0.125', 'Cholangiocyte': '0.253', 'NK-cells (Liver)': '-0.136', 'Respiratory ciliated cells': '0.184', 'Mitotic cells (Lung)': '-0.141', 'NK-cells (Lung)': '0.372', 'B-cells (Lung)': '0.116', 'Alpha cells': '0.484', 'Beta cells': '0.359', 'Prostate glandular cells': '0.186', 'Prostate basal glandular cells': '0.112', 'Urothelial cells': '-0.104', 'Keratinocyte (other)': '-0.341', 'Keratinocyte (granular)': '-0.270', 'Hair cortex cells': '0.154', 'Inner root sheath cells': '0.093', 'Outer root sheath cells': '0.280', 'Sebaceous gland cells': '0.020', 'Eccrine sweat gland cells': '0.405', 'Adipocytes (Skin)': '0.264', 'Mitotic cells (Skin)': '0.019', 'Parietal cells': '-0.612', 'Chief cells': '-0.460', 'Gastric mucous cells': '-0.476', 'Gastric enteroendocrine cells': '-0.327', 'Mitotic cells (Stomach)': '-0.171', 'Parafollicular cells': '0.022', 'Thyroid glandular cells': '-0.034', 'Mitotic cells (Thyroid)': '0.046', 'Adrenal cortex cells': '0.159', 'Adrenal medulla cells': '0.213', 'Mitotic cells (Adrenal gland)': '0.107', 'Minor salivary glandular cells': '0.442', 'Minor salivary gland ductal cells': '0.351', 'Minor salivary gland basal cells': '-0.273', 'Mitotic cells (Minor salivary gland)': '-0.421', 'Adipocytes (Minor salivary gland)': '-0.075', 'Somatotropes': '-0.278', 'Lactotropes': '-0.011', 'Gonadotropes': '0.214', 'Corticotropes': '-0.086', 'Thyrotropes': '0.219', 'Undifferentiated cells (Pituitary gland)': '0.333', 'Mitotic cells (Spleen)': '-0.397', 'Platelets': '-0.171', 'Erythrocytes': '-0.086', 'Hematopoietic stem cells': '-0.354', 'B-cells (Spleen)': '0.226', 'NK-cells (Spleen)': '0.281', 'Amygdala excitatory': '20.5', 'Cerebellar inhibitory': '12.7', 'Cge interneuron': '20.3', 'Deep-layer corticothalamic and 6b': '25.9', 'Deep-layer intratelencephalic': '23.3', 'Deep-layer near-projecting': '21.2', 'Eccentric medium spiny neuron': '16.6', 'Hippocampal ca1-3': '21.1', 'Hippocampal ca4': '16.6', 'Hippocampal dentate gyrus': '12.7', 'Lamp5-lhx6 and chandelier': '21.0', 'Lower rhombic lip': '21.7', 'Mammillary body': '15.4', 'Medium spiny neuron': '12.8', 'Mge interneuron': '19.3', 'Midbrain-derived inhibitory': '34.0', 'Miscellaneous': '21.1', 'Splatter': '16.7', 'Thalamic excitatory': '20.7', 'Upper rhombic lip': '31.4', 'Upper-layer intratelencephalic': '22.1', 'Astrocyte': '10.1', 'Bergmann glia': '9.2', 'Central nervous system macrophage': '9.5', 'Choroid plexus epithelial cell': '3.7', 'Committed oligodendrocyte precursor': '12.6', 'Ependymal cell': '5.2', 'Oligodendrocyte': '15.5', 'Oligodendrocyte precursor cell': '11.2', 'Endothelial cell': '14.0', 'Pericyte': '16.6', 'Vascular associated smooth muscle cell': '13.9', 'Fibroblast': '13.5', 'Leukocyte': '6.7', 'Basophil': '6.7', 'Eosinophil': '0.5', 'Neutrophil': '2.1', 'Classical monocyte': '13.4', 'Non-classical monocyte': '7.6', 'Intermediate monocyte': '4.5', 'T-reg': '2.1', 'GdT-cell': '0.5', 'MAIT T-cell': '4.4', 'Memory CD4 T-cell': '0.4', 'Naive CD4 T-cell': '10.2', 'Memory CD8 T-cell': '0.4', 'Naive CD8 T-cell': '9.3', 'Memory B-cell': '0.1', 'Naive B-cell': '7.4', 'Plasmacytoid DC': '1.4', 'Myeloid DC': '6.2', 'NK-cell': '18.4', 'Total PBMC': '2.7', 'Vd2 gdTCR': '4.2', 'Memory CD4 T-cell Th1\\/Th17': '11.0', 'Memory CD4 T-cell Th17': '13.4', 'Memory CD4 T-cell Th2': '12.3', 'Non-Vd2 gdTCR': '6.9', 'Memory CD4 T-cell Th1': '12.9', 'Memory CD4 T-cell TFH': '13.6', 'Terminal effector memory CD4 T-cell': '9.2', 'Central memory CD8 T-cell': '1.1', 'Effector memory CD8 T-cell': '3.7', 'Terminal effector memory CD8 T-cell': '3.4', 'Non-switched memory B-cell': '1.9', 'Plasmablast': '0.3', 'Switched memory B-cell': '2.0', 'Exhausted memory B-cell': '1.7', 'Progenitor cell': '3.9', 'Memory T-reg': '14.2', 'Naive CD4 T-cell activated': '4.1', 'Naive CD8 T-cell activated': '4.7', 'Naive T-reg': '9.9'}
7O0B, 7QRW, 8AMR
{'Adipose Tissue': 15.995526578073092, 'Adrenal Gland': 6.926104651162791, 'Bladder': 20.767619047619046, 'Blood': 3.0819308934337997, 'Blood Vessel': 26.789330337078653, 'Brain': 28.75113349735049, 'Breast': 21.02602396514161, 'Cervix Uteri': 25.929263157894734, 'Colon': 20.822940949935816, 'Esophagus': 14.713867820069204, 'Fallopian Tube': 23.26555555555556, 'Heart': 6.1021161440185825, 'Kidney': 7.885269662921348, 'Liver': 5.314053097345133, 'Lung': 21.31820242214533, 'Muscle': 7.669161892901618, 'Nerve': 31.077915993537964, 'Ovary': 19.07497777777778, 'Pancreas': 4.9334847560975605, 'Pituitary': 12.569254416961131, 'Prostate': 21.015779591836736, 'Salivary Gland': 14.29141975308642, 'Skin': 13.737883360972912, 'Small Intestine': 21.71072192513369, 'Spleen': 12.217771784232363, 'Stomach': 14.288077994428969, 'Testis': 8.707102493074792, 'Thyroid': 16.040655436447167, 'Uterus': 29.908732394366197, 'Vagina': 19.93869871794872}
BECN1
MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK
Homo sapiens
Cytoplasm, Golgi apparatus, trans-Golgi network membrane, Endosome membrane, Endoplasmic reticulum membrane, Mitochondrion membrane, Endosome, Cytoplasmic vesicle, autophagosome, Mitochondrion, Nucleus, Cytoplasm, Mitochondrion
Low tissue specificity
{'Ciliated cells': '35.9', 'Basal respiratory cells': '36.8', 'Club cells': '35.7', 'Ionocytes': '22.8', 'Mucus glandular cells': '35.9', 'Serous glandular cells': '26.2', 'Gastric mucus-secreting cells': '44.2', 'Proximal enterocytes': '46.3', 'Paneth cells': '36.1', 'Distal enterocytes': '62.8', 'Intestinal goblet cells': '62.2', 'Exocrine glandular cells': '-0.572', 'Basal prostatic cells': '24.9', 'Prostatic glandular cells': '32.2', 'Breast glandular cells': '0.259', 'Breast myoepithelial cells': '0.166', 'Glandular and luminal cells': '33.8', 'Secretory cells': '27.3', 'Basal keratinocytes': '31.1', 'Suprabasal keratinocytes': '49.2', 'Basal squamous epithelial cells': '36.1', 'Squamous epithelial cells': '46.0', 'Alveolar cells type 1': '0.108', 'Alveolar cells type 2': '0.269', 'Salivary duct cells': '29.6', 'Ductal cells': '0.487', 'Hepatocytes': '0.621', 'Cholangiocytes': '38.2', 'Proximal tubular cells': '0.239', 'Distal tubular cells': '58.4', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.131', 'Sertoli cells': '0.342', 'Granulosa cells': '9.8', 'Enteroendocrine cells': '45.4', 'Pancreatic endocrine cells': '42.4', 'Leydig cells': '0.394', 'Excitatory neurons': '11.7', 'Inhibitory neurons': '11.2', 'Cone photoreceptor cells': '6.8', 'Rod photoreceptor cells': '14.3', 'Bipolar cells': '11.7', 'Horizontal cells': '6.3', 'Astrocytes': '11.1', 'Oligodendrocyte precursor cells': '5.2', 'Oligodendrocytes': '9.1', 'Microglial cells': '3.6', 'Muller glia cells': '30.0', 'Schwann cells': '0.098', 'Spermatogonia': '0.560', 'Spermatocytes': '0.538', 'Early spermatids': '0.025', 'Late spermatids': '-0.306', 'Oocytes': '14.0', 'Cytotrophoblasts': '23.5', 'Syncytiotrophoblasts': '40.1', 'Extravillous trophoblasts': '34.3', 'Endothelial cells': '36.0', 'Lymphatic endothelial cells': '26.7', 'Cardiomyocytes': '0.685', 'Skeletal myocytes': '-0.187', 'Smooth muscle cells': '32.8', 'Adipocytes': '40.5', 'Melanocytes': '0.181', 'Fibroblasts': '25.6', 'Peritubular cells': '0.336', 'Endometrial stromal cells': '28.7', 'Ovarian stromal cells': '19.6', 'Undifferentiated cells': '49.7', 'T-cells': '39.4', 'B-cells': '34.9', 'Plasma cells': '45.6', 'Nk-cells': '48.4', 'Granulocytes': '26.6', 'Monocytes': '64.0', 'Macrophages': '44.0', 'Hofbauer cells': '44.0', 'Kupffer cells': '63.5', 'Dendritic cells': '36.1', 'Langerhans cells': '0.296', 'Erythroid cells': '-0.103', 'Adipocytes (Subcutaneous)': '0.183', 'Adipocytes (Visceral)': '0.062', 'Breast glandular cells (progenitors)': '0.129', 'Adipocytes (Breast)': '-0.085', 'Colon enterocytes': '-0.080', 'Colon enteroendocrine cells': '0.108', 'Enteric glia cells': '-0.443', 'Mitotic cells (Colon)': '-0.006', 'Mitotic cells (Heart)': '0.461', 'Podocytes': '0.009', 'Ascending Loop of Henle cells': '0.391', 'Intercalated cells': '0.090', 'Cholangiocyte': '0.325', 'NK-cells (Liver)': '-0.403', 'Respiratory ciliated cells': '-0.020', 'Mitotic cells (Lung)': '0.134', 'NK-cells (Lung)': '-0.202', 'B-cells (Lung)': '-0.248', 'Alpha cells': '0.274', 'Beta cells': '0.117', 'Prostate glandular cells': '-0.019', 'Prostate basal glandular cells': '0.160', 'Urothelial cells': '-0.007', 'Keratinocyte (other)': '0.168', 'Keratinocyte (granular)': '-0.011', 'Hair cortex cells': '0.086', 'Inner root sheath cells': '0.200', 'Outer root sheath cells': '0.223', 'Sebaceous gland cells': '0.114', 'Eccrine sweat gland cells': '-0.015', 'Adipocytes (Skin)': '-0.059', 'Mitotic cells (Skin)': '0.290', 'Parietal cells': '-0.427', 'Chief cells': '-0.388', 'Gastric mucous cells': '-0.256', 'Gastric enteroendocrine cells': '-0.398', 'Mitotic cells (Stomach)': '0.098', 'Parafollicular cells': '0.066', 'Thyroid glandular cells': '0.272', 'Mitotic cells (Thyroid)': '0.088', 'Adrenal cortex cells': '0.792', 'Adrenal medulla cells': '0.052', 'Mitotic cells (Adrenal gland)': '0.475', 'Minor salivary glandular cells': '0.477', 'Minor salivary gland ductal cells': '-0.037', 'Minor salivary gland basal cells': '0.402', 'Mitotic cells (Minor salivary gland)': '0.411', 'Adipocytes (Minor salivary gland)': '0.093', 'Somatotropes': '0.047', 'Lactotropes': '-0.141', 'Gonadotropes': '-0.103', 'Corticotropes': '-0.233', 'Thyrotropes': '-0.021', 'Undifferentiated cells (Pituitary gland)': '0.254', 'Mitotic cells (Spleen)': '-0.126', 'Platelets': '-0.010', 'Erythrocytes': '-0.172', 'Hematopoietic stem cells': '-0.093', 'B-cells (Spleen)': '0.228', 'NK-cells (Spleen)': '0.192', 'Amygdala excitatory': '19.3', 'Cerebellar inhibitory': '21.5', 'Cge interneuron': '18.6', 'Deep-layer corticothalamic and 6b': '20.3', 'Deep-layer intratelencephalic': '22.3', 'Deep-layer near-projecting': '19.4', 'Eccentric medium spiny neuron': '19.2', 'Hippocampal ca1-3': '20.9', 'Hippocampal ca4': '20.1', 'Hippocampal dentate gyrus': '21.3', 'Lamp5-lhx6 and chandelier': '20.0', 'Lower rhombic lip': '21.5', 'Mammillary body': '23.5', 'Medium spiny neuron': '21.5', 'Mge interneuron': '23.1', 'Midbrain-derived inhibitory': '19.7', 'Miscellaneous': '20.4', 'Splatter': '19.4', 'Thalamic excitatory': '23.7', 'Upper rhombic lip': '17.5', 'Upper-layer intratelencephalic': '21.2', 'Astrocyte': '24.1', 'Bergmann glia': '17.8', 'Central nervous system macrophage': '24.4', 'Choroid plexus epithelial cell': '24.6', 'Committed oligodendrocyte precursor': '17.4', 'Ependymal cell': '21.3', 'Oligodendrocyte': '20.4', 'Oligodendrocyte precursor cell': '14.8', 'Endothelial cell': '21.9', 'Pericyte': '19.3', 'Vascular associated smooth muscle cell': '20.1', 'Fibroblast': '20.3', 'Leukocyte': '24.6', 'Basophil': '141.3', 'Eosinophil': '122.5', 'Neutrophil': '284.4', 'Classical monocyte': '37.5', 'Non-classical monocyte': '52.2', 'Intermediate monocyte': '228.9', 'T-reg': '183.8', 'GdT-cell': '103.4', 'MAIT T-cell': '148.3', 'Memory CD4 T-cell': '114.7', 'Naive CD4 T-cell': '49.8', 'Memory CD8 T-cell': '111.6', 'Naive CD8 T-cell': '48.1', 'Memory B-cell': '113.1', 'Naive B-cell': '48.3', 'Plasmacytoid DC': '181.1', 'Myeloid DC': '180.3', 'NK-cell': '55.4', 'Total PBMC': '176.2', 'Vd2 gdTCR': '172.1', 'Memory CD4 T-cell Th1\\/Th17': '50.1', 'Memory CD4 T-cell Th17': '53.4', 'Memory CD4 T-cell Th2': '53.8', 'Non-Vd2 gdTCR': '181.4', 'Memory CD4 T-cell Th1': '53.0', 'Memory CD4 T-cell TFH': '57.4', 'Terminal effector memory CD4 T-cell': '217.3', 'Central memory CD8 T-cell': '174.6', 'Effector memory CD8 T-cell': '202.1', 'Terminal effector memory CD8 T-cell': '180.3', 'Non-switched memory B-cell': '163.0', 'Plasmablast': '228.7', 'Switched memory B-cell': '169.5', 'Exhausted memory B-cell': '168.5', 'Progenitor cell': '97.2', 'Memory T-reg': '60.5', 'Naive CD4 T-cell activated': '46.3', 'Naive CD8 T-cell activated': '53.5', 'Naive T-reg': '46.3'}
2P1L, 2PON, 3DVU, 4DDP, 4MI8, 5EFM, 5HHE, 5VAU, 5VAX, 5VAY, 6DCN, 6DCO, 6HOI, 6HOJ, 6HOK, 7BL1, 8SOR, 8SRQ
{'Adipose Tissue': 47.237915282392024, 'Adrenal Gland': 36.50977131782946, 'Bladder': 54.96666666666666, 'Blood': 33.65780516684607, 'Blood Vessel': 57.91269662921348, 'Brain': 23.576771915215748, 'Breast': 46.54520697167756, 'Cervix Uteri': 43.93, 'Colon': 53.48463286264442, 'Esophagus': 52.16688027681661, 'Fallopian Tube': 43.95666666666667, 'Heart': 22.353779907084785, 'Kidney': 25.891764044943823, 'Liver': 12.622491150442478, 'Lung': 42.12282006920415, 'Muscle': 47.73143212951432, 'Nerve': 49.03636510500807, 'Ovary': 39.117, 'Pancreas': 15.508756097560976, 'Pituitary': 25.99188339222615, 'Prostate': 39.544734693877544, 'Salivary Gland': 42.093271604938266, 'Skin': 48.119773355445, 'Small Intestine': 45.32465240641711, 'Spleen': 36.083734439834025, 'Stomach': 40.40699164345404, 'Testis': 32.47005540166205, 'Thyroid': 39.45241960183768, 'Uterus': 46.47894366197183, 'Vagina': 41.65596153846154}
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[1.0, 1.0, 0.83, 0.94, 0.9, 0.91, 0.86, 0.88, 0.88, 0.79, 0.89, 0.85, 0.85, 0.67, 0.64, 0.2, 0.43, 0.0, 0.53, 0.48, 0.37, 0.61, 0.65, 0.75, 0.22, 0.97, 0.32, 0.57, 0.59, 0.53, 0.26, 0.63, 0.85, 0.29, 0.63, 0.85, 0.6, 0.42, 0.25, 0.74, 0.72, 0.51, 0.33, 0.55, 0.66, 0.81, 0.86, 0.85, 0.88, 0.84, 0.97, 0.97, 0.98, 0.92, 0.92, 0.94, 0.97, 1.0, 0.97, 0.97, 0.95, 0.93, 0.96, 0.92, 0.93, 0.98, 0.98, 0.99, 0.94, 0.99, 0.86, 0.88, 0.88, 0.94, 0.95, 0.87, 0.97, 0.67, 0.93, 0.86, 0.92, 0.84, 0.89, 0.8, 0.86, 0.8, 0.94, 0.91, 0.93, 0.95, 0.93, 1.0, 0.99, 0.94, 0.99, 0.87, 0.95, 0.84, 0.78, 0.91, 0.81, 0.96, 0.97, 0.87, 0.96, 1.0, 0.82, 0.68, 0.83, 0.73, 0.63, 0.46, 0.61, 0.69, 0.4, 0.26, 0.67, 0.31, 0.03, 0.25, 0.44, 0.1, 0.09, 0.68, 0.3, 0.4, 0.2, 0.78, 0.6, 0.45, 1.0, 0.32, 0.63, 0.22, 0.11, 0.2, 0.17, 0.75, 0.74, 0.12, 0.37, 0.5, 0.42, 0.24, 0.54, 0.63, 0.53, 0.46, 0.61, 0.59, 0.64, 0.62, 0.64, 0.54, 0.46, 0.55, 0.51, 0.5, 0.47, 0.41, 0.41, 0.64, 0.63, 0.53, 0.5, 0.57, 0.55, 0.57, 0.6, 0.82, 0.79, 0.4, 0.52, 0.75, 0.66, 0.32, 0.33, 0.67, 0.58, 0.5, 0.55, 0.65, 0.49, 0.68, 0.65, 0.67, 0.55, 0.45, 0.7, 0.34, 0.6, 0.52, 0.6, 0.52, 0.43, 0.52, 0.57, 0.57, 0.51, 0.48, 0.57, 0.46, 0.52, 0.54, 0.73, 0.6, 0.53, 0.63, 0.48, 0.58, 0.46, 0.55, 0.68, 0.6, 0.61, 0.53, 0.52, 0.52, 0.41, 0.6, 0.51, 0.54, 0.59, 0.67, 0.48, 0.54, 0.34, 0.55, 0.67, 0.52, 0.69, 0.43, 0.6, 0.57, 0.5, 0.61, 0.41, 0.52, 0.46, 0.49, 0.58, 0.47, 0.65, 0.41, 0.66, 0.6, 0.65, 0.59, 0.44, 0.5, 0.49, 0.58, 0.63, 0.57, 0.58, 0.63, 0.54, 0.57, 0.44, 0.35, 0.5, 0.48, 0.54, 0.7, 0.5, 0.77, 0.6, 0.24, 0.68, 0.18, 0.51, 0.73, 0.58, 0.06, 0.45, 0.07, 0.61, 0.69, 0.48, 0.68, 0.56, 0.05, 0.02, 0.07, 0.0, 0.3, 0.71, 0.34, 0.24, 0.0, 0.0, 0.32, 0.06, 0.7, 0.81, 0.44, 0.63, 0.03, 0.76, 0.12, 0.68, 0.21, 0.0, 0.07, 0.18, 0.0, 0.0, 0.06, 0.26, 0.0, 0.0, 0.39, 0.0, 0.0, 0.4, 0.28, 0.0, 0.02, 0.72, 0.5, 0.29, 0.65, 0.18, 0.9, 0.14, 0.81, 0.54, 0.26, 0.6, 0.05, 0.2, 0.35, 0.67, 0.54, 0.46, 0.47, 0.0, 0.23, 0.0, 0.28, 0.1, 0.45, 0.87, 0.43, 0.83, 0.79, 0.5, 0.61, 0.06, 0.16, 0.01, 0.39, 0.08, 0.9, 0.17, 0.67, 0.74, 0.75, 0.08, 0.64, 0.8, 0.28, 0.41, 0.58, 0.03, 0.07, 0.52, 0.0, 0.0, 0.18, 0.03, 0.0, 0.0, 0.06, 0.0, 0.01, 0.18, 0.08, 0.01, 0.13, 0.47, 0.36, 0.01, 0.31, 0.7, 0.7, 0.42, 0.91, 0.94, 0.16, 0.6, 0.07, 0.29, 0.19, 0.59, 0.06, 0.19, 0.23, 0.92, 0.57, 0.0, 0.34, 0.0, 0.3, 0.13, 0.64, 0.89, 0.76, 0.65, 0.71, 0.19, 0.45, 0.17, 0.15, 0.0, 0.34, 0.1, 0.45, 1.0, 0.22, 0.51, 0.2, 0.53, 0.41, 0.02, 0.01, 0.35, 0.0, 0.0, 0.29, 0.13, 0.0, 0.01, 0.26, 0.01, 0.01, 0.39, 0.48, 0.0, 0.03, 0.51, 0.12, 0.01, 0.14, 0.45, 0.4, 0.41, 0.59, 0.87, 0.79]
RING finger
Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3
CART
null
TRIM2, MYO5B,ACTN4, ZFYVE28, KIF21B , HGS TRIM3
GKAP, CDKN1A, TLR3
63
null
null
Homooligomer
null
83.98836
0.421976
76.585267
0.510178
1,770
O75382
Q5VSY0
20352094
UbiNet, UbiBrowser
TRIM3
MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKAVRRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ
Homo sapiens
Cytoplasm, Early endosome, Golgi apparatus, trans-Golgi network, Cell projection, dendrite
Tissue enhanced (brain)
{'Ciliated cells': '8.6', 'Basal respiratory cells': '2.9', 'Club cells': '6.0', 'Ionocytes': '3.7', 'Mucus glandular cells': '3.6', 'Serous glandular cells': '12.3', 'Gastric mucus-secreting cells': '5.3', 'Proximal enterocytes': '25.8', 'Paneth cells': '5.4', 'Distal enterocytes': '18.9', 'Intestinal goblet cells': '17.5', 'Exocrine glandular cells': '-0.523', 'Basal prostatic cells': '2.4', 'Prostatic glandular cells': '8.0', 'Breast glandular cells': '0.656', 'Breast myoepithelial cells': '0.445', 'Glandular and luminal cells': '6.1', 'Secretory cells': '2.9', 'Basal keratinocytes': '4.6', 'Suprabasal keratinocytes': '3.2', 'Basal squamous epithelial cells': '4.2', 'Squamous epithelial cells': '3.5', 'Alveolar cells type 1': '0.138', 'Alveolar cells type 2': '-0.547', 'Salivary duct cells': '3.9', 'Ductal cells': '0.534', 'Hepatocytes': '0.259', 'Cholangiocytes': '1.9', 'Proximal tubular cells': '0.216', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.436', 'Sertoli cells': '0.330', 'Granulosa cells': '2.6', 'Enteroendocrine cells': '6.9', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.450', 'Excitatory neurons': '12.7', 'Inhibitory neurons': '11.7', 'Cone photoreceptor cells': '11.9', 'Rod photoreceptor cells': '9.4', 'Bipolar cells': '9.4', 'Horizontal cells': '6.3', 'Astrocytes': '9.3', 'Oligodendrocyte precursor cells': '4.7', 'Oligodendrocytes': '9.4', 'Microglial cells': '10.7', 'Muller glia cells': '2.1', 'Schwann cells': '0.335', 'Spermatogonia': '0.359', 'Spermatocytes': '0.030', 'Early spermatids': '-0.540', 'Late spermatids': '-0.543', 'Oocytes': '11.0', 'Cytotrophoblasts': '1.7', 'Syncytiotrophoblasts': '1.1', 'Extravillous trophoblasts': '2.2', 'Endothelial cells': '6.7', 'Lymphatic endothelial cells': '9.3', 'Cardiomyocytes': '0.422', 'Skeletal myocytes': '-0.193', 'Smooth muscle cells': '9.6', 'Adipocytes': '8.0', 'Melanocytes': '-0.172', 'Fibroblasts': '6.6', 'Peritubular cells': '0.545', 'Endometrial stromal cells': '4.3', 'Ovarian stromal cells': '4.6', 'Undifferentiated cells': '4.8', 'T-cells': '3.6', 'B-cells': '2.5', 'Plasma cells': '1.1', 'Nk-cells': '4.0', 'Granulocytes': '2.1', 'Monocytes': '2.0', 'Macrophages': '4.0', 'Hofbauer cells': '4.7', 'Kupffer cells': '1.0', 'Dendritic cells': '0.8', 'Langerhans cells': '-0.051', 'Erythroid cells': '-0.017', 'Adipocytes (Subcutaneous)': '-0.432', 'Adipocytes (Visceral)': '-0.417', 'Breast glandular cells (progenitors)': '0.413', 'Adipocytes (Breast)': '-0.486', 'Colon enterocytes': '-0.078', 'Colon enteroendocrine cells': '0.167', 'Enteric glia cells': '0.327', 'Mitotic cells (Colon)': '-0.142', 'Mitotic cells (Heart)': '0.491', 'Podocytes': '-0.134', 'Ascending Loop of Henle cells': '0.378', 'Intercalated cells': '-0.125', 'Cholangiocyte': '0.253', 'NK-cells (Liver)': '-0.136', 'Respiratory ciliated cells': '0.184', 'Mitotic cells (Lung)': '-0.141', 'NK-cells (Lung)': '0.372', 'B-cells (Lung)': '0.116', 'Alpha cells': '0.484', 'Beta cells': '0.359', 'Prostate glandular cells': '0.186', 'Prostate basal glandular cells': '0.112', 'Urothelial cells': '-0.104', 'Keratinocyte (other)': '-0.341', 'Keratinocyte (granular)': '-0.270', 'Hair cortex cells': '0.154', 'Inner root sheath cells': '0.093', 'Outer root sheath cells': '0.280', 'Sebaceous gland cells': '0.020', 'Eccrine sweat gland cells': '0.405', 'Adipocytes (Skin)': '0.264', 'Mitotic cells (Skin)': '0.019', 'Parietal cells': '-0.612', 'Chief cells': '-0.460', 'Gastric mucous cells': '-0.476', 'Gastric enteroendocrine cells': '-0.327', 'Mitotic cells (Stomach)': '-0.171', 'Parafollicular cells': '0.022', 'Thyroid glandular cells': '-0.034', 'Mitotic cells (Thyroid)': '0.046', 'Adrenal cortex cells': '0.159', 'Adrenal medulla cells': '0.213', 'Mitotic cells (Adrenal gland)': '0.107', 'Minor salivary glandular cells': '0.442', 'Minor salivary gland ductal cells': '0.351', 'Minor salivary gland basal cells': '-0.273', 'Mitotic cells (Minor salivary gland)': '-0.421', 'Adipocytes (Minor salivary gland)': '-0.075', 'Somatotropes': '-0.278', 'Lactotropes': '-0.011', 'Gonadotropes': '0.214', 'Corticotropes': '-0.086', 'Thyrotropes': '0.219', 'Undifferentiated cells (Pituitary gland)': '0.333', 'Mitotic cells (Spleen)': '-0.397', 'Platelets': '-0.171', 'Erythrocytes': '-0.086', 'Hematopoietic stem cells': '-0.354', 'B-cells (Spleen)': '0.226', 'NK-cells (Spleen)': '0.281', 'Amygdala excitatory': '20.5', 'Cerebellar inhibitory': '12.7', 'Cge interneuron': '20.3', 'Deep-layer corticothalamic and 6b': '25.9', 'Deep-layer intratelencephalic': '23.3', 'Deep-layer near-projecting': '21.2', 'Eccentric medium spiny neuron': '16.6', 'Hippocampal ca1-3': '21.1', 'Hippocampal ca4': '16.6', 'Hippocampal dentate gyrus': '12.7', 'Lamp5-lhx6 and chandelier': '21.0', 'Lower rhombic lip': '21.7', 'Mammillary body': '15.4', 'Medium spiny neuron': '12.8', 'Mge interneuron': '19.3', 'Midbrain-derived inhibitory': '34.0', 'Miscellaneous': '21.1', 'Splatter': '16.7', 'Thalamic excitatory': '20.7', 'Upper rhombic lip': '31.4', 'Upper-layer intratelencephalic': '22.1', 'Astrocyte': '10.1', 'Bergmann glia': '9.2', 'Central nervous system macrophage': '9.5', 'Choroid plexus epithelial cell': '3.7', 'Committed oligodendrocyte precursor': '12.6', 'Ependymal cell': '5.2', 'Oligodendrocyte': '15.5', 'Oligodendrocyte precursor cell': '11.2', 'Endothelial cell': '14.0', 'Pericyte': '16.6', 'Vascular associated smooth muscle cell': '13.9', 'Fibroblast': '13.5', 'Leukocyte': '6.7', 'Basophil': '6.7', 'Eosinophil': '0.5', 'Neutrophil': '2.1', 'Classical monocyte': '13.4', 'Non-classical monocyte': '7.6', 'Intermediate monocyte': '4.5', 'T-reg': '2.1', 'GdT-cell': '0.5', 'MAIT T-cell': '4.4', 'Memory CD4 T-cell': '0.4', 'Naive CD4 T-cell': '10.2', 'Memory CD8 T-cell': '0.4', 'Naive CD8 T-cell': '9.3', 'Memory B-cell': '0.1', 'Naive B-cell': '7.4', 'Plasmacytoid DC': '1.4', 'Myeloid DC': '6.2', 'NK-cell': '18.4', 'Total PBMC': '2.7', 'Vd2 gdTCR': '4.2', 'Memory CD4 T-cell Th1\\/Th17': '11.0', 'Memory CD4 T-cell Th17': '13.4', 'Memory CD4 T-cell Th2': '12.3', 'Non-Vd2 gdTCR': '6.9', 'Memory CD4 T-cell Th1': '12.9', 'Memory CD4 T-cell TFH': '13.6', 'Terminal effector memory CD4 T-cell': '9.2', 'Central memory CD8 T-cell': '1.1', 'Effector memory CD8 T-cell': '3.7', 'Terminal effector memory CD8 T-cell': '3.4', 'Non-switched memory B-cell': '1.9', 'Plasmablast': '0.3', 'Switched memory B-cell': '2.0', 'Exhausted memory B-cell': '1.7', 'Progenitor cell': '3.9', 'Memory T-reg': '14.2', 'Naive CD4 T-cell activated': '4.1', 'Naive CD8 T-cell activated': '4.7', 'Naive T-reg': '9.9'}
7O0B, 7QRW, 8AMR
{'Adipose Tissue': 15.995526578073092, 'Adrenal Gland': 6.926104651162791, 'Bladder': 20.767619047619046, 'Blood': 3.0819308934337997, 'Blood Vessel': 26.789330337078653, 'Brain': 28.75113349735049, 'Breast': 21.02602396514161, 'Cervix Uteri': 25.929263157894734, 'Colon': 20.822940949935816, 'Esophagus': 14.713867820069204, 'Fallopian Tube': 23.26555555555556, 'Heart': 6.1021161440185825, 'Kidney': 7.885269662921348, 'Liver': 5.314053097345133, 'Lung': 21.31820242214533, 'Muscle': 7.669161892901618, 'Nerve': 31.077915993537964, 'Ovary': 19.07497777777778, 'Pancreas': 4.9334847560975605, 'Pituitary': 12.569254416961131, 'Prostate': 21.015779591836736, 'Salivary Gland': 14.29141975308642, 'Skin': 13.737883360972912, 'Small Intestine': 21.71072192513369, 'Spleen': 12.217771784232363, 'Stomach': 14.288077994428969, 'Testis': 8.707102493074792, 'Thyroid': 16.040655436447167, 'Uterus': 29.908732394366197, 'Vagina': 19.93869871794872}
GKAP1
MASAVLSSVPTTASRFALLQVDSGSGSDSEPGKGKGRNTGKSQTLGSKSTTNEKKREKRRKKKEQQQSEANELRNLAFKKIPQKSSHAVCNAQHDLPLSNPVQKDSREENWQEWRQRDEQLTSEMFEADLEKALLLSKLEYEEHKKEYEDAENTSTQSKVMNKKDKRKNHQGKDRPLTVSLKDFHSEDHISKKTEELSSSQTLSHDGGFFNRLEDDVHKILIREKRREQLTEYNGTDNCTAHEHNQEVVLKDGRIERLKLELERKDAEIQKLKNVITQWEAKYKEVKARNAQLLKMLQEGEMKDKAEILLQVDESQSIKNELTIQVTSLHAALEQERSKVKVLQAELAKYQGGRKGKRNSESDQCR
Homo sapiens
Golgi apparatus
Tissue enriched (testis)
{'Ciliated cells': '12.1', 'Basal respiratory cells': '2.2', 'Club cells': '11.0', 'Ionocytes': '1.5', 'Mucus glandular cells': '8.3', 'Serous glandular cells': '8.1', 'Gastric mucus-secreting cells': '5.9', 'Proximal enterocytes': '8.7', 'Paneth cells': '6.9', 'Distal enterocytes': '3.2', 'Intestinal goblet cells': '9.9', 'Exocrine glandular cells': '-0.420', 'Basal prostatic cells': '17.2', 'Prostatic glandular cells': '18.1', 'Breast glandular cells': '0.257', 'Breast myoepithelial cells': '0.232', 'Glandular and luminal cells': '13.0', 'Secretory cells': '23.7', 'Basal keratinocytes': '6.3', 'Suprabasal keratinocytes': '4.3', 'Basal squamous epithelial cells': '5.1', 'Squamous epithelial cells': '3.3', 'Alveolar cells type 1': '0.335', 'Alveolar cells type 2': '-0.400', 'Salivary duct cells': '9.7', 'Ductal cells': '0.434', 'Hepatocytes': '0.260', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.123', 'Distal tubular cells': '12.3', 'Collecting duct cells': '19.4', 'Mesothelial cells': '0.395', 'Sertoli cells': '-0.498', 'Granulosa cells': '48.9', 'Enteroendocrine cells': '12.4', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '-0.539', 'Excitatory neurons': '19.1', 'Inhibitory neurons': '31.3', 'Cone photoreceptor cells': '49.3', 'Rod photoreceptor cells': '73.3', 'Bipolar cells': '54.9', 'Horizontal cells': '51.6', 'Astrocytes': '30.3', 'Oligodendrocyte precursor cells': '34.0', 'Oligodendrocytes': '39.2', 'Microglial cells': '25.9', 'Muller glia cells': '46.8', 'Schwann cells': '0.208', 'Spermatogonia': '-0.287', 'Spermatocytes': '0.121', 'Early spermatids': '0.920', 'Late spermatids': '0.619', 'Oocytes': '206.6', 'Cytotrophoblasts': '8.9', 'Syncytiotrophoblasts': '3.0', 'Extravillous trophoblasts': '2.7', 'Endothelial cells': '11.4', 'Lymphatic endothelial cells': '9.4', 'Cardiomyocytes': '0.696', 'Skeletal myocytes': '-0.185', 'Smooth muscle cells': '13.4', 'Adipocytes': '13.5', 'Melanocytes': '-0.114', 'Fibroblasts': '8.3', 'Peritubular cells': '-0.337', 'Endometrial stromal cells': '4.2', 'Ovarian stromal cells': '28.9', 'Undifferentiated cells': '13.1', 'T-cells': '14.6', 'B-cells': '16.9', 'Plasma cells': '12.4', 'Nk-cells': '12.4', 'Granulocytes': '13.3', 'Monocytes': '3.7', 'Macrophages': '7.1', 'Hofbauer cells': '3.5', 'Kupffer cells': '4.2', 'Dendritic cells': '10.3', 'Langerhans cells': '0.041', 'Erythroid cells': '0.170', 'Adipocytes (Subcutaneous)': '0.236', 'Adipocytes (Visceral)': '-0.048', 'Breast glandular cells (progenitors)': '0.086', 'Adipocytes (Breast)': '-0.185', 'Colon enterocytes': '-0.291', 'Colon enteroendocrine cells': '0.166', 'Enteric glia cells': '0.336', 'Mitotic cells (Colon)': '-0.301', 'Mitotic cells (Heart)': '0.378', 'Podocytes': '0.142', 'Ascending Loop of Henle cells': '0.378', 'Intercalated cells': '0.168', 'Cholangiocyte': '0.067', 'NK-cells (Liver)': '0.132', 'Respiratory ciliated cells': '0.166', 'Mitotic cells (Lung)': '-0.219', 'NK-cells (Lung)': '0.362', 'B-cells (Lung)': '0.122', 'Alpha cells': '0.318', 'Beta cells': '0.280', 'Prostate glandular cells': '0.097', 'Prostate basal glandular cells': '-0.022', 'Urothelial cells': '-0.098', 'Keratinocyte (other)': '-0.211', 'Keratinocyte (granular)': '-0.312', 'Hair cortex cells': '0.144', 'Inner root sheath cells': '0.163', 'Outer root sheath cells': '0.416', 'Sebaceous gland cells': '0.100', 'Eccrine sweat gland cells': '0.418', 'Adipocytes (Skin)': '0.165', 'Mitotic cells (Skin)': '0.237', 'Parietal cells': '-0.596', 'Chief cells': '-0.458', 'Gastric mucous cells': '-0.595', 'Gastric enteroendocrine cells': '-0.363', 'Mitotic cells (Stomach)': '-0.242', 'Parafollicular cells': '0.087', 'Thyroid glandular cells': '0.345', 'Mitotic cells (Thyroid)': '-0.079', 'Adrenal cortex cells': '0.247', 'Adrenal medulla cells': '0.010', 'Mitotic cells (Adrenal gland)': '0.097', 'Minor salivary glandular cells': '0.315', 'Minor salivary gland ductal cells': '0.292', 'Minor salivary gland basal cells': '-0.201', 'Mitotic cells (Minor salivary gland)': '-0.146', 'Adipocytes (Minor salivary gland)': '0.022', 'Somatotropes': '0.443', 'Lactotropes': '0.084', 'Gonadotropes': '0.104', 'Corticotropes': '-0.069', 'Thyrotropes': '0.121', 'Undifferentiated cells (Pituitary gland)': '0.000', 'Mitotic cells (Spleen)': '-0.182', 'Platelets': '-0.338', 'Erythrocytes': '-0.026', 'Hematopoietic stem cells': '-0.274', 'B-cells (Spleen)': '0.319', 'NK-cells (Spleen)': '0.334', 'Amygdala excitatory': '36.9', 'Cerebellar inhibitory': '49.5', 'Cge interneuron': '48.6', 'Deep-layer corticothalamic and 6b': '40.3', 'Deep-layer intratelencephalic': '34.6', 'Deep-layer near-projecting': '47.4', 'Eccentric medium spiny neuron': '57.9', 'Hippocampal ca1-3': '27.6', 'Hippocampal ca4': '14.5', 'Hippocampal dentate gyrus': '25.4', 'Lamp5-lhx6 and chandelier': '46.3', 'Lower rhombic lip': '51.8', 'Mammillary body': '61.0', 'Medium spiny neuron': '25.8', 'Mge interneuron': '49.8', 'Midbrain-derived inhibitory': '50.3', 'Miscellaneous': '34.8', 'Splatter': '57.2', 'Thalamic excitatory': '38.7', 'Upper rhombic lip': '98.0', 'Upper-layer intratelencephalic': '27.7', 'Astrocyte': '76.4', 'Bergmann glia': '72.9', 'Central nervous system macrophage': '71.5', 'Choroid plexus epithelial cell': '141.7', 'Committed oligodendrocyte precursor': '66.7', 'Ependymal cell': '95.7', 'Oligodendrocyte': '68.1', 'Oligodendrocyte precursor cell': '82.1', 'Endothelial cell': '58.6', 'Pericyte': '29.7', 'Vascular associated smooth muscle cell': '43.4', 'Fibroblast': '58.6', 'Leukocyte': '43.7', 'Basophil': '4.1', 'Eosinophil': '0.2', 'Neutrophil': '4.7', 'Classical monocyte': '2.2', 'Non-classical monocyte': '3.2', 'Intermediate monocyte': '0.6', 'T-reg': '3.1', 'GdT-cell': '0.5', 'MAIT T-cell': '4.9', 'Memory CD4 T-cell': '0.5', 'Naive CD4 T-cell': '18.5', 'Memory CD8 T-cell': '0.5', 'Naive CD8 T-cell': '15.5', 'Memory B-cell': '0.7', 'Naive B-cell': '17.0', 'Plasmacytoid DC': '1.5', 'Myeloid DC': '0.9', 'NK-cell': '9.2', 'Total PBMC': '2.7', 'Vd2 gdTCR': '5.9', 'Memory CD4 T-cell Th1\\/Th17': '14.6', 'Memory CD4 T-cell Th17': '12.3', 'Memory CD4 T-cell Th2': '13.5', 'Non-Vd2 gdTCR': '3.9', 'Memory CD4 T-cell Th1': '12.1', 'Memory CD4 T-cell TFH': '10.3', 'Terminal effector memory CD4 T-cell': '3.8', 'Central memory CD8 T-cell': '3.8', 'Effector memory CD8 T-cell': '4.6', 'Terminal effector memory CD8 T-cell': '5.9', 'Non-switched memory B-cell': '3.1', 'Plasmablast': '1.9', 'Switched memory B-cell': '4.8', 'Exhausted memory B-cell': '5.7', 'Progenitor cell': '4.2', 'Memory T-reg': '6.6', 'Naive CD4 T-cell activated': '6.4', 'Naive CD8 T-cell activated': '8.5', 'Naive T-reg': '15.8'}
null
{'Adipose Tissue': 6.307179651162791, 'Adrenal Gland': 4.517725968992248, 'Bladder': 8.565809523809524, 'Blood': 1.4369566523143165, 'Blood Vessel': 9.417029962546817, 'Brain': 8.413218281604845, 'Breast': 6.809124183006536, 'Cervix Uteri': 10.576947368421052, 'Colon': 9.252126187419767, 'Esophagus': 6.940737370242214, 'Fallopian Tube': 11.412333333333333, 'Heart': 5.17599268292683, 'Kidney': 3.928677528089888, 'Liver': 4.034180088495575, 'Lung': 5.5915, 'Muscle': 19.073826899128267, 'Nerve': 6.565547657512116, 'Ovary': 16.64192222222222, 'Pancreas': 3.5477073170731703, 'Pituitary': 14.53549116607774, 'Prostate': 10.561477551020408, 'Salivary Gland': 4.353836419753087, 'Skin': 1.837809922609176, 'Small Intestine': 5.837459893048129, 'Spleen': 4.714983402489627, 'Stomach': 6.3774456824512535, 'Testis': 188.5903047091413, 'Thyroid': 11.640450229709035, 'Uterus': 13.268422535211268, 'Vagina': 6.070602564102564}
[38.99, 37.18, 33.31, 37.88, 36.18, 35.06, 33.8, 34.58, 34.12, 35.78, 32.01, 34.63, 33.04, 40.01, 47.16, 50.61, 55.19, 62.37, 72.9, 82.07, 86.64, 89.06, 88.07, 87.68, 90.44, 89.2, 87.11, 86.38, 88.36, 86.18, 86.85, 90.75, 89.41, 91.13, 88.57, 85.76, 85.44, 88.44, 88.7, 89.98, 92.38, 92.46, 91.37, 91.6, 93.15, 89.99, 88.5, 88.3, 87.15, 82.73, 75.55, 68.36, 71.5, 77.27, 80.85, 85.08, 83.49, 89.15, 86.04, 86.88, 86.24, 86.65, 88.77, 85.08, 87.0, 82.63, 85.02, 81.57, 79.77, 78.56, 78.86, 82.21, 85.81, 83.96, 84.07, 84.37, 83.89, 84.72, 83.87, 79.46, 78.09, 80.61, 79.48, 75.78, 75.72, 76.43, 76.75, 71.68, 68.65, 68.46, 61.22, 50.45, 48.1, 45.0, 42.14, 39.09, 39.3, 42.66, 51.36, 47.34, 41.05, 40.91, 43.26, 43.79, 46.0, 47.14, 45.14, 50.49, 51.37, 56.41, 64.17, 66.88, 72.25, 77.77, 79.98, 75.39, 78.81, 80.21, 79.34, 78.57, 83.64, 84.92, 85.07, 85.86, 88.68, 90.23, 88.64, 85.77, 86.27, 83.88, 86.16, 85.91, 86.15, 87.9, 89.57, 87.05, 88.24, 86.39, 87.37, 86.35, 87.72, 83.73, 84.19, 84.88, 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[1.0, 0.98, 0.88, 0.91, 0.86, 0.9, 0.9, 0.85, 0.85, 0.91, 0.87, 0.95, 0.81, 0.64, 0.99, 0.9, 0.66, 0.88, 0.83, 0.84, 0.72, 0.87, 0.78, 0.87, 1.0, 0.85, 0.96, 0.93, 0.95, 0.93, 0.91, 0.85, 0.95, 0.88, 0.99, 0.93, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 0.96, 0.61, 0.83, 0.77, 0.62, 0.58, 0.72, 0.68, 0.54, 0.69, 0.75, 0.73, 0.59, 0.73, 0.62, 0.7, 0.7, 0.66, 0.53, 0.64, 0.53, 0.56, 0.51, 0.5, 0.6, 0.58, 0.69, 0.53, 0.65, 0.82, 0.76, 0.78, 0.9, 0.84, 0.82, 0.88, 0.92, 0.84, 0.93, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.91, 0.99, 0.87, 0.99, 0.8, 0.68, 0.63, 0.83, 0.82, 0.53, 0.5, 0.71, 0.5, 0.56, 0.51, 0.61, 0.44, 0.63, 0.69, 0.63, 0.63, 0.71, 0.61, 0.62, 0.62, 0.56, 0.56, 0.52, 0.62, 0.64, 0.71, 0.62, 0.49, 0.55, 0.52, 0.63, 0.6, 0.48, 0.62, 0.63, 0.47, 0.53, 0.6, 0.55, 0.54, 0.71, 0.53, 0.6, 0.55, 0.56, 0.62, 0.51, 0.75, 0.52, 0.45, 0.5, 0.73, 0.64, 0.57, 0.73, 0.82, 0.94, 0.81, 0.99, 0.93, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.96, 0.99, 0.99, 1.0, 1.0, 1.0, 0.97, 1.0, 0.83, 0.92, 0.87, 0.73, 0.5, 0.74, 0.8, 0.62, 0.82, 0.7, 0.76, 0.87, 0.97, 0.92, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.96, 0.82, 0.93, 0.91, 0.8, 0.97, 0.72, 0.96, 0.61, 0.91, 0.2, 0.67, 0.75, 0.61, 0.55, 0.41, 0.59, 0.56, 0.43, 0.53, 0.56, 0.55, 0.5, 0.61, 0.5, 0.59, 0.51, 0.64, 0.66, 0.61, 0.68, 0.54, 0.53, 0.62, 0.8, 0.8, 0.6, 0.53, 0.82, 0.88, 0.91, 1.0, 0.75, 0.52, 0.75, 0.79, 0.68, 0.59, 0.49, 0.5, 0.54, 0.67, 0.6, 0.54, 0.48, 0.22, 0.64, 0.64, 0.43, 0.64, 0.55, 0.59, 0.61, 0.34, 0.61, 0.51, 0.56, 0.52, 0.54, 0.57, 0.48, 0.44, 0.57, 0.7, 0.53, 0.53, 0.53, 0.39, 0.55, 0.54, 0.58, 0.65, 0.51, 0.52, 0.5, 0.68, 0.7, 0.68, 0.54, 0.64, 0.54, 0.67, 0.53, 0.54, 0.6, 0.45, 0.66, 0.58, 0.58, 0.53, 0.68, 0.54, 0.42, 0.67, 0.69, 0.67, 0.54, 0.66, 0.53, 0.53, 0.56, 0.65, 0.58, 0.52, 0.58, 0.69, 0.54, 0.55, 0.4, 0.55, 0.59, 0.54, 0.48, 0.52, 0.52, 0.54, 0.62, 0.45, 0.64, 0.6, 0.55, 0.68, 0.63, 0.46, 0.41, 0.49, 0.45, 0.61, 0.5, 0.51, 0.45, 0.51, 0.46, 0.64, 0.55, 0.54, 0.57, 0.48, 0.45, 0.58, 0.56, 0.74, 0.76, 0.77, 0.59, 0.65, 0.89, 0.92, 0.9, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0]
RING finger
Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3
CART
null
TRIM2, MYO5B,ACTN4, ZFYVE28, KIF21B , HGS TRIM3
GKAP, CDKN1A, TLR3
63
null
null
Homooligomer
null
83.98836
0.421976
71.290355
0.711257
2,112
O75592
P49815
14559897, E3NethUbiquitome
UbiNet, UbiBrowser, 31181401
MYCBP2
MMMCAATASPAAASSGLGGDGFYPAATFSSSPAPGALFMPVPDGSVAAAGLGLGLPAADSRGHYQLLLSGRALADRYRRIYTAALNDRDQGGGSAGHPASRNKKILNKKKLKRKQKSKSKVKTRSKSENLENTVIIPDIKLHSNPSAFNIYCNVRHCVLEWQKKEISLAAASKNSVQSGESDSDEEEESKEPPIKLPKIIEVGLCEVFELIKETRFSHPSLCLRSLQALLNVLQGQQPEGLQSEPPEVLESLFQLLLEITVRSTGMNDSTGQSLTALSCACLFSLVASWGETGRTLQAISAILTNNGSHACQTIQVPTILNSLQRSVQAVLVGKIQIQDWFSNGIKKAALMHKWPLKEISVDEDDQCLLQNDGFFLYLLCKDGLYKIGSGYSGTVRGHIYNSTSRIRNRKEKKSWLGYAQGYLLYRDVNNHSMTAIRISPETLEQDGTVMLPDCHTEGQNILFTDGEYINQIAASRDDGFVVRIFATSTEPVLQQELQLKLARKCLHACGISLFDLEKDLHIISTGFDEESAILGAGREFALMKTANGKIYYTGKYQSLGIKQGGPSAGKWVELPITKSPKIVHFSVGHDGSHALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSVISKDGELYMFGKDAIYSDSSSLVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCGRDTGAMNQGGKGFGVENMATAMDEDLEEELDEKDEKSMMCPPGMHKWKLEQCMVCTVCGDCTGYGASCVSSGRPDRVPGGICGCGSGESGCAVCGCCKACARELDGQEARQRGILDAVKEMIPLDLLLAVPVPGVNIEEHLQLRQEEKRQRVIRRHRLEEGRGPLVFAGPIFMNHREQALARLRSHPAQLKHKRDKHKDGSGERGEKDASKITTYPPGSVRFDCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGASGDQTFLRIDEALINSHVLATSEIFASKHIIGLVPASISEPPPFKCLLINKVDGSCKTFNDSEQEDLQGFGVCLDPVYDVIWRFRPNTRELWCYNAVVADARLPSAADMQSRCSILSPELALPTGSRALTTRSHAALHILGCLDTLAAMQDLKMGVASTEEETQAVMKVYSKEDYSVVNRFESHGGGWGYSAHSVEAIRFSADTDILLGGLGLFGGRGEYTAKIKLFELGPDGGDHETDGDLLAETDVLAYDCAAREKYAMMFDEPVLLQAGWWYVAWARVSGPSSDCGSHGQASITTDDGVVFQFKSSKKSNNGTDVNAGQIPQLLYRLPTSDGSASKGKQQTSEPVHILKRSFARTVSVECFESLLSILHWSWTTLVLGVEELRGLKGFQFTATLLDLERLRFVGTCCLRLLRVYTCEIYPVSATGKAVVEETSKLAECIGKTRTLLRKILSEGVDHCMVKLDNDPQGYLSQPLSLLEAVLQECHNTFTACFHSFYPTPALQWACLCDLLNCLDQDIQEANFKTSSSRLLAAVMSALCHTSVKLTSIFPIAYDGEVLLRSIVKQVSTENDSTLVHRFPLLVAHMEKLSQSEENISGMTSFREVLEKMLVIVVLPVRNSLRRENELFSSHLVSNTCGLLASIVSELTASALGSEVDGLNSLHSVKASANRFTKTSQGRSWNTGNGSPDAICFSVDKPGIVVVGFSVYGGGGIHEYELEVLVDDSEHAGDSTHSHRWTSLELVKGTYTTDDSPSDIAEIRLDKVVPLKENVKYAVRLRNYGSRTANGDGGMTTVQCPDGVTFTFSTCSLSSNGTNQTRGQIPQILYYRSEFDGDLQSQLLSKANEEDKNCSRALSVVSTVVRASKDLLHRALAVDADDIPELLSSSSLFSMLLPLIIAYIGPVAAAIPKVAVEVFGLVQQLLPSVAILNQKYAPPAFNPNQSTDSTTGNQPEQGLSACTTSSHYAVIESEHPYKPACVMHYKVTFPECVRWMTIEFDPQCGTAQSEDVLRLLIPVRTVQNSGYGPKLTSVHENLNSWIELKKFSGSSGWPTMVLVLPGNEALFSLETASDYVKDDKASFYGFKCFAIGYEFSPGPDEGVIQLEKELANLGGVCAAALMKKDLALPIGNELEEDLEILEEAALQVCKTHSGILGKGLALSHSPTILEALEGNLPLQIQSNEQSFLDDFIACVPGSSGGRLARWLQPDSYADPQKTSLILNKDDIRCGWPTTITVQTKDQYGDVVHVPNMKVEVKAVPVSQKKMSLQQDQAKKPQRIPGSPAVTAASSNTDMTYGGLASPKLDVSYEPMIVKEARYIAITMMKVYENYSFEELRFASPTPKRPSENMLIRVNNDGTYCANWTPGAIGLYTLHVTIDGIEIDAGLEVKVKDPPKGMIPPGTQLVKPKSEPQPNKVRKFVAKDSAGLRIRSHPSLQSEQIGIVKVNGTITFIDEIHNDDGVWLRLNDETIKKYVPNMNGYTEAWCLSFNQHLGKSLLVPVDESKTNTDDFFKDINSCCPQEATMQEQDMPFLRGGPGMYKVVKTGPSGHNIRSCPNLRGIPIGMLVLGNKVKAVGEVTNSEGTWVQLDQNSMVEFCESDEGEAWSLARDRGGNQYLRHEDEQALLDQNSQTPPPSPFSVQAFNKGASCSAQGFDYGLGNSKGDRGNISTSSKPASTSGKSELSSKHSRSLKPDGRMSRTTADQKKPRGTESLSASESLILKSDAAKLRSDSHSRSLSPNHNTLQTLKSDGRMPSSSRAESPGPGSRLSSPKPKTLPANRSSPSGASSPRSSSPHDKNLPQKSTAPVKTKLDPPRERSKSDSYTLDPDTLRKKKMPLTEPLRGRSTSPKPKSVPKDSTDSPGSENRAPSPHVVQENLHSEVVEVCTSSTLKTNSLTDSTCDDSSEFKSVDEGSNKVHFSIGKAPLKDEQEMRASPKISRKCANRHTRPKKEKSSFLFKGDGSKPLEPAKQAMSPSVAECARAVFASFLWHEGIVHDAMACSSFLKFHPELSKEHAPIRSSLNSQQPTEEKETKLKNRHSLEISSALNMFNIAPHGPDISKMGSINKNKVLSMLKEPPLHEKCEDGKTETTFEMSMHNTMKSKSPLPLTLQHLVAFWEDISLATIKAASQNMIFPSPGSCAVLKKKECEKENKKSKKEKKKKEKAEVRPRGNLFGEMAQLAVGGPEKDTICELCGESHPYPVTYHMRQAHPGCGRYAGGQGYNSIGHFCGGWAGNCGDGGIGGSTWYLVCDRCREKYLREKQAAAREKVKQSRRKPMQVKTPRALPTMEAHQVIKANALFLLSLSSAAEPSILCYHPAKPFQSQLPSVKEGISEDLPVKMPCLYLQTLARHHHENFVGYQDDNLFQDEMRYLRSTSVPAPYISVTPDASPNVFEEPESNMKSMPPSLETSPITDTDLAKRTVFQRSYSVVASEYDKQHSILPARVKAIPRRRVNSGDTEVGSSLLRHPSPELSRLISAHSSLSKGERNFQWPVLAFVIQHHDLEGLEIAMKQALRKSACRVFAMEAFNWLLCNVIQTTSLHDILWHFVASLTPAPVEPEEEEDEENKTSKENSEQEKDTRVCEHPLSDIVIAGEAAHPLPHTFHRLLQTISDLMMSLPSGSSLQQMALRCWSLKFKQSDHQFLHQSNVFHHINNILSKSDDGDSEESFSISIQSGFEAMSQELCIVMCLKDLTSIVDIKTSSRPAMIGSLTDGSTETFWESGDEDKNKTKNITINCVKGINARYVSVHVDNSRDLGNKVTSMTFLTGKAVEDLCRIKQVDLDSRHIGWVTSELPGGDNHIIKIELKGPENTLRVRQVKVLGWKDGESTKIAGQISASVAQQRNCEAETLRVFRLITSQVFGKLISGDAEPTPEQEEKALLSSPEGEEKVYNATSDADLKEHMVGIIFSRSKLTNLQKQVCAHIVQAIRMEATRVREEWEHAISSKENANSQPNDEDASSDAYCFELLSMVLALSGSNVGRQYLAQQLTLLQDLFSLLHTASPRVQRQVTSLLRRVLPEVTPSRLASIIGVKSLPPADISDIIHSTEKGDWNKLGILDMFLGCIAKALTVQLKAKGTTITGTAGTTVGKGVTTVTLPMIFNSSYLRRGESHWWMKGSTPTQISEIIIKLIKDMAAGHLSEAWSRVTKNAIAETIIALTKMEEEFRSPVRCIATTRLWLALASLCVLDQDHVDRLSSGRWMGKDGQQKQMPMCDNHDDGETAAIILCNVCGNLCTDCDRFLHLHRRTKTHQRQVFKEEEEAIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREHTGKPTTSSSEACRFCGSRSGTELSAVGSVCSDADCQEYAKIACSKTHPCGHPCGGVKNEEHCLPCLHGCDKSATSLKQDADDMCMICFTEALSAAPAIQLDCSHIFHLQCCRRVLENRWLGPRITFGFISCPICKNKINHIVLKDLLDPIKELYEDVRRKALMRLEYEGLHKSEAITTPGVRFYNDPAGYAMNRYAYYVCYKCRKAYFGGEARCDAEAGRGDDYDPRELICGACSDVSRAQMCPKHGTDFLEYKCRYCCSVAVFFCFGTTHFCNACHDDFQRMTSIPKEELPHCPAGPKGKQLEGTECPLHVVHPPTGEEFALGCGVCRNAHTF
Homo sapiens
Nucleus, Cell projection, axon, Cytoplasm, cytoskeleton
Low tissue specificity
{'Ciliated cells': '36.2', 'Basal respiratory cells': '30.5', 'Club cells': '53.6', 'Ionocytes': '28.7', 'Mucus glandular cells': '71.8', 'Serous glandular cells': '103.1', 'Gastric mucus-secreting cells': '39.5', 'Proximal enterocytes': '12.1', 'Paneth cells': '13.8', 'Distal enterocytes': '12.7', 'Intestinal goblet cells': '15.7', 'Exocrine glandular cells': '-0.498', 'Basal prostatic cells': '49.1', 'Prostatic glandular cells': '119.8', 'Breast glandular cells': '-0.244', 'Breast myoepithelial cells': '-0.357', 'Glandular and luminal cells': '62.9', 'Secretory cells': '71.9', 'Basal keratinocytes': '139.0', 'Suprabasal keratinocytes': '233.8', 'Basal squamous epithelial cells': '80.2', 'Squamous epithelial cells': '134.8', 'Alveolar cells type 1': '0.015', 'Alveolar cells type 2': '-0.253', 'Salivary duct cells': '73.8', 'Ductal cells': '0.544', 'Hepatocytes': '0.502', 'Cholangiocytes': '28.6', 'Proximal tubular cells': '0.190', 'Distal tubular cells': '6.1', 'Collecting duct cells': '35.0', 'Mesothelial cells': '-0.242', 'Sertoli cells': '0.212', 'Granulosa cells': '37.2', 'Enteroendocrine cells': '31.9', 'Pancreatic endocrine cells': '13.6', 'Leydig cells': '0.251', 'Excitatory neurons': '411.2', 'Inhibitory neurons': '451.5', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '103.7', 'Bipolar cells': '219.1', 'Horizontal cells': '218.4', 'Astrocytes': '150.5', 'Oligodendrocyte precursor cells': '317.9', 'Oligodendrocytes': '197.8', 'Microglial cells': '270.2', 'Muller glia cells': '113.6', 'Schwann cells': '0.291', 'Spermatogonia': '0.467', 'Spermatocytes': '0.526', 'Early spermatids': '-0.048', 'Late spermatids': '-0.304', 'Oocytes': '43.4', 'Cytotrophoblasts': '46.7', 'Syncytiotrophoblasts': '43.2', 'Extravillous trophoblasts': '32.7', 'Endothelial cells': '94.0', 'Lymphatic endothelial cells': '55.4', 'Cardiomyocytes': '0.613', 'Skeletal myocytes': '-0.134', 'Smooth muscle cells': '93.8', 'Adipocytes': '90.1', 'Melanocytes': '0.263', 'Fibroblasts': '101.5', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '58.3', 'Ovarian stromal cells': '84.2', 'Undifferentiated cells': '25.1', 'T-cells': '139.4', 'B-cells': '187.6', 'Plasma cells': '115.3', 'Nk-cells': '120.8', 'Granulocytes': '90.0', 'Monocytes': '158.5', 'Macrophages': '113.7', 'Hofbauer cells': '48.8', 'Kupffer cells': '88.8', 'Dendritic cells': '105.7', 'Langerhans cells': '0.350', 'Erythroid cells': '-0.073', 'Adipocytes (Subcutaneous)': '0.355', 'Adipocytes (Visceral)': '0.420', 'Breast glandular cells (progenitors)': '-0.257', 'Adipocytes (Breast)': '0.606', 'Colon enterocytes': '-0.140', 'Colon enteroendocrine cells': '0.306', 'Enteric glia cells': '-0.037', 'Mitotic cells (Colon)': '-0.065', 'Mitotic cells (Heart)': '0.494', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.498', 'Intercalated cells': '-0.003', 'Cholangiocyte': '0.231', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '0.033', 'Mitotic cells (Lung)': '0.018', 'NK-cells (Lung)': '0.145', 'B-cells (Lung)': '0.092', 'Alpha cells': '0.363', 'Beta cells': '0.200', 'Prostate glandular cells': '-0.204', 'Prostate basal glandular cells': '0.017', 'Urothelial cells': '0.100', 'Keratinocyte (other)': '0.446', 'Keratinocyte (granular)': '0.334', 'Hair cortex cells': '-0.162', 'Inner root sheath cells': '-0.114', 'Outer root sheath cells': '-0.158', 'Sebaceous gland cells': '0.022', 'Eccrine sweat gland cells': '-0.293', 'Adipocytes (Skin)': '-0.162', 'Mitotic cells (Skin)': '0.202', 'Parietal cells': '-0.648', 'Chief cells': '-0.512', 'Gastric mucous cells': '-0.496', 'Gastric enteroendocrine cells': '-0.416', 'Mitotic cells (Stomach)': '-0.054', 'Parafollicular cells': '-0.017', 'Thyroid glandular cells': '0.232', 'Mitotic cells (Thyroid)': '0.223', 'Adrenal cortex cells': '0.673', 'Adrenal medulla cells': '0.215', 'Mitotic cells (Adrenal gland)': '0.411', 'Minor salivary glandular cells': '0.050', 'Minor salivary gland ductal cells': '-0.120', 'Minor salivary gland basal cells': '0.642', 'Mitotic cells (Minor salivary gland)': '0.672', 'Adipocytes (Minor salivary gland)': '0.370', 'Somatotropes': '0.320', 'Lactotropes': '0.078', 'Gonadotropes': '-0.024', 'Corticotropes': '-0.198', 'Thyrotropes': '0.046', 'Undifferentiated cells (Pituitary gland)': '0.134', 'Mitotic cells (Spleen)': '-0.072', 'Platelets': '-0.081', 'Erythrocytes': '-0.151', 'Hematopoietic stem cells': '-0.196', 'B-cells (Spleen)': '0.435', 'NK-cells (Spleen)': '0.203', 'Amygdala excitatory': '723.8', 'Cerebellar inhibitory': '645.2', 'Cge interneuron': '607.8', 'Deep-layer corticothalamic and 6b': '482.7', 'Deep-layer intratelencephalic': '668.6', 'Deep-layer near-projecting': '435.6', 'Eccentric medium spiny neuron': '671.6', 'Hippocampal ca1-3': '625.3', 'Hippocampal ca4': '594.4', 'Hippocampal dentate gyrus': '848.5', 'Lamp5-lhx6 and chandelier': '672.9', 'Lower rhombic lip': '636.4', 'Mammillary body': '648.1', 'Medium spiny neuron': '678.3', 'Mge interneuron': '687.8', 'Midbrain-derived inhibitory': '520.2', 'Miscellaneous': '559.6', 'Splatter': '577.7', 'Thalamic excitatory': '580.4', 'Upper rhombic lip': '508.1', 'Upper-layer intratelencephalic': '708.8', 'Astrocyte': '328.1', 'Bergmann glia': '352.2', 'Central nervous system macrophage': '849.4', 'Choroid plexus epithelial cell': '198.8', 'Committed oligodendrocyte precursor': '308.4', 'Ependymal cell': '837.2', 'Oligodendrocyte': '323.3', 'Oligodendrocyte precursor cell': '545.1', 'Endothelial cell': '331.6', 'Pericyte': '422.3', 'Vascular associated smooth muscle cell': '296.0', 'Fibroblast': '398.4', 'Leukocyte': '570.1', 'Basophil': '10.6', 'Eosinophil': '1.5', 'Neutrophil': '12.7', 'Classical monocyte': '41.8', 'Non-classical monocyte': '70.0', 'Intermediate monocyte': '29.9', 'T-reg': '23.7', 'GdT-cell': '1.9', 'MAIT T-cell': '21.0', 'Memory CD4 T-cell': '2.1', 'Naive CD4 T-cell': '143.1', 'Memory CD8 T-cell': '1.4', 'Naive CD8 T-cell': '114.2', 'Memory B-cell': '3.1', 'Naive B-cell': '170.9', 'Plasmacytoid DC': '11.7', 'Myeloid DC': '27.0', 'NK-cell': '86.3', 'Total PBMC': '20.1', 'Vd2 gdTCR': '23.1', 'Memory CD4 T-cell Th1\\/Th17': '109.1', 'Memory CD4 T-cell Th17': '108.8', 'Memory CD4 T-cell Th2': '118.9', 'Non-Vd2 gdTCR': '21.3', 'Memory CD4 T-cell Th1': '109.7', 'Memory CD4 T-cell TFH': '108.6', 'Terminal effector memory CD4 T-cell': '27.3', 'Central memory CD8 T-cell': '27.0', 'Effector memory CD8 T-cell': '28.1', 'Terminal effector memory CD8 T-cell': '21.8', 'Non-switched memory B-cell': '33.2', 'Plasmablast': '23.7', 'Switched memory B-cell': '33.2', 'Exhausted memory B-cell': '30.4', 'Progenitor cell': '17.8', 'Memory T-reg': '99.8', 'Naive CD4 T-cell activated': '109.3', 'Naive CD8 T-cell activated': '106.4', 'Naive T-reg': '129.1'}
5O6C, 6T7F
{'Adipose Tissue': 28.831866279069768, 'Adrenal Gland': 8.582108527131783, 'Bladder': 16.713809523809523, 'Blood': 11.589389235737352, 'Blood Vessel': 25.14011835205992, 'Brain': 16.480912187736564, 'Breast': 23.59864705882353, 'Cervix Uteri': 23.956315789473685, 'Colon': 12.481729139922978, 'Esophagus': 15.357815224913496, 'Fallopian Tube': 18.05777777777778, 'Heart': 6.1763454123112655, 'Kidney': 6.056449438202248, 'Liver': 3.7727477876106192, 'Lung': 16.354984429065745, 'Muscle': 7.081652552926526, 'Nerve': 26.11060743134087, 'Ovary': 26.55622222222222, 'Pancreas': 5.381393292682927, 'Pituitary': 15.922915194346292, 'Prostate': 13.769273469387755, 'Salivary Gland': 13.314876543209875, 'Skin': 32.49827860696517, 'Small Intestine': 16.56797860962567, 'Spleen': 21.57757676348548, 'Stomach': 9.303451253481894, 'Testis': 16.818326869806096, 'Thyroid': 17.588114854517613, 'Uterus': 19.83394366197183, 'Vagina': 22.515583333333332}
TSC2
MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNSPPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
Homo sapiens
Lysosome membrane, Cytoplasm, cytosol
Low tissue specificity
{'Ciliated cells': '32.7', 'Basal respiratory cells': '11.5', 'Club cells': '29.6', 'Ionocytes': '25.4', 'Mucus glandular cells': '24.6', 'Serous glandular cells': '26.6', 'Gastric mucus-secreting cells': '48.9', 'Proximal enterocytes': '26.6', 'Paneth cells': '18.8', 'Distal enterocytes': '35.7', 'Intestinal goblet cells': '30.4', 'Exocrine glandular cells': '-0.609', 'Basal prostatic cells': '143.0', 'Prostatic glandular cells': '29.2', 'Breast glandular cells': '0.623', 'Breast myoepithelial cells': '0.497', 'Glandular and luminal cells': '56.1', 'Secretory cells': '14.2', 'Basal keratinocytes': '17.7', 'Suprabasal keratinocytes': '21.4', 'Basal squamous epithelial cells': '13.1', 'Squamous epithelial cells': '14.2', 'Alveolar cells type 1': '0.124', 'Alveolar cells type 2': '-0.121', 'Salivary duct cells': '24.2', 'Ductal cells': '0.513', 'Hepatocytes': '0.309', 'Cholangiocytes': '24.8', 'Proximal tubular cells': '0.080', 'Distal tubular cells': '6.1', 'Collecting duct cells': '15.6', 'Mesothelial cells': '0.364', 'Sertoli cells': '0.083', 'Granulosa cells': '26.4', 'Enteroendocrine cells': '35.8', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '0.008', 'Excitatory neurons': '22.0', 'Inhibitory neurons': '21.5', 'Cone photoreceptor cells': '71.4', 'Rod photoreceptor cells': '158.9', 'Bipolar cells': '98.5', 'Horizontal cells': '124.0', 'Astrocytes': '41.5', 'Oligodendrocyte precursor cells': '17.5', 'Oligodendrocytes': '24.0', 'Microglial cells': '15.2', 'Muller glia cells': '35.1', 'Schwann cells': '0.361', 'Spermatogonia': '0.349', 'Spermatocytes': '0.343', 'Early spermatids': '0.005', 'Late spermatids': '-0.087', 'Oocytes': '52.2', 'Cytotrophoblasts': '16.0', 'Syncytiotrophoblasts': '13.4', 'Extravillous trophoblasts': '9.7', 'Endothelial cells': '28.6', 'Lymphatic endothelial cells': '37.8', 'Cardiomyocytes': '0.641', 'Skeletal myocytes': '-0.297', 'Smooth muscle cells': '24.3', 'Adipocytes': '22.2', 'Melanocytes': '-0.080', 'Fibroblasts': '22.8', 'Peritubular cells': '0.171', 'Endometrial stromal cells': '23.6', 'Ovarian stromal cells': '35.4', 'Undifferentiated cells': '20.2', 'T-cells': '22.8', 'B-cells': '21.0', 'Plasma cells': '15.0', 'Nk-cells': '32.4', 'Granulocytes': '11.6', 'Monocytes': '15.0', 'Macrophages': '17.0', 'Hofbauer cells': '17.1', 'Kupffer cells': '14.5', 'Dendritic cells': '13.3', 'Langerhans cells': '0.108', 'Erythroid cells': '-0.062', 'Adipocytes (Subcutaneous)': '-0.049', 'Adipocytes (Visceral)': '-0.076', 'Breast glandular cells (progenitors)': '0.524', 'Adipocytes (Breast)': '-0.480', 'Colon enterocytes': '-0.187', 'Colon enteroendocrine cells': '0.213', 'Enteric glia cells': '0.329', 'Mitotic cells (Colon)': '-0.240', 'Mitotic cells (Heart)': '0.464', 'Podocytes': '-0.104', 'Ascending Loop of Henle cells': '0.574', 'Intercalated cells': '-0.002', 'Cholangiocyte': '0.187', 'NK-cells (Liver)': '-0.116', 'Respiratory ciliated cells': '0.152', 'Mitotic cells (Lung)': '-0.012', 'NK-cells (Lung)': '0.079', 'B-cells (Lung)': '-0.039', 'Alpha cells': '0.450', 'Beta cells': '0.340', 'Prostate glandular cells': '0.081', 'Prostate basal glandular cells': '0.331', 'Urothelial cells': '0.239', 'Keratinocyte (other)': '-0.174', 'Keratinocyte (granular)': '-0.034', 'Hair cortex cells': '0.092', 'Inner root sheath cells': '0.080', 'Outer root sheath cells': '0.262', 'Sebaceous gland cells': '0.155', 'Eccrine sweat gland cells': '0.064', 'Adipocytes (Skin)': '0.154', 'Mitotic cells (Skin)': '0.068', 'Parietal cells': '-0.496', 'Chief cells': '-0.423', 'Gastric mucous cells': '-0.222', 'Gastric enteroendocrine cells': '-0.276', 'Mitotic cells (Stomach)': '0.056', 'Parafollicular cells': '0.096', 'Thyroid glandular cells': '0.325', 'Mitotic cells (Thyroid)': '-0.085', 'Adrenal cortex cells': '0.275', 'Adrenal medulla cells': '0.343', 'Mitotic cells (Adrenal gland)': '0.255', 'Minor salivary glandular cells': '0.386', 'Minor salivary gland ductal cells': '0.434', 'Minor salivary gland basal cells': '-0.038', 'Mitotic cells (Minor salivary gland)': '-0.110', 'Adipocytes (Minor salivary gland)': '0.055', 'Somatotropes': '0.253', 'Lactotropes': '0.284', 'Gonadotropes': '-0.030', 'Corticotropes': '0.514', 'Thyrotropes': '0.207', 'Undifferentiated cells (Pituitary gland)': '-0.284', 'Mitotic cells (Spleen)': '-0.375', 'Platelets': '-0.179', 'Erythrocytes': '-0.106', 'Hematopoietic stem cells': '-0.343', 'B-cells (Spleen)': '0.328', 'NK-cells (Spleen)': '0.315', 'Amygdala excitatory': '35.6', 'Cerebellar inhibitory': '35.2', 'Cge interneuron': '35.0', 'Deep-layer corticothalamic and 6b': '37.8', 'Deep-layer intratelencephalic': '37.3', 'Deep-layer near-projecting': '34.5', 'Eccentric medium spiny neuron': '38.5', 'Hippocampal ca1-3': '39.8', 'Hippocampal ca4': '28.0', 'Hippocampal dentate gyrus': '29.4', 'Lamp5-lhx6 and chandelier': '30.7', 'Lower rhombic lip': '21.5', 'Mammillary body': '28.3', 'Medium spiny neuron': '39.0', 'Mge interneuron': '32.8', 'Midbrain-derived inhibitory': '28.9', 'Miscellaneous': '34.3', 'Splatter': '29.8', 'Thalamic excitatory': '31.7', 'Upper rhombic lip': '36.6', 'Upper-layer intratelencephalic': '36.7', 'Astrocyte': '73.6', 'Bergmann glia': '46.8', 'Central nervous system macrophage': '26.9', 'Choroid plexus epithelial cell': '26.4', 'Committed oligodendrocyte precursor': '48.4', 'Ependymal cell': '39.2', 'Oligodendrocyte': '47.2', 'Oligodendrocyte precursor cell': '42.2', 'Endothelial cell': '36.3', 'Pericyte': '39.2', 'Vascular associated smooth muscle cell': '30.0', 'Fibroblast': '28.9', 'Leukocyte': '25.3', 'Basophil': '29.8', 'Eosinophil': '2.8', 'Neutrophil': '30.4', 'Classical monocyte': '20.7', 'Non-classical monocyte': '20.7', 'Intermediate monocyte': '25.9', 'T-reg': '20.3', 'GdT-cell': '3.1', 'MAIT T-cell': '22.8', 'Memory CD4 T-cell': '1.9', 'Naive CD4 T-cell': '25.0', 'Memory CD8 T-cell': '1.7', 'Naive CD8 T-cell': '30.8', 'Memory B-cell': '1.8', 'Naive B-cell': '20.9', 'Plasmacytoid DC': '19.5', 'Myeloid DC': '19.9', 'NK-cell': '35.6', 'Total PBMC': '18.5', 'Vd2 gdTCR': '26.1', 'Memory CD4 T-cell Th1\\/Th17': '24.9', 'Memory CD4 T-cell Th17': '33.9', 'Memory CD4 T-cell Th2': '35.8', 'Non-Vd2 gdTCR': '35.2', 'Memory CD4 T-cell Th1': '39.3', 'Memory CD4 T-cell TFH': '50.1', 'Terminal effector memory CD4 T-cell': '34.9', 'Central memory CD8 T-cell': '25.8', 'Effector memory CD8 T-cell': '29.3', 'Terminal effector memory CD8 T-cell': '28.5', 'Non-switched memory B-cell': '25.5', 'Plasmablast': '28.7', 'Switched memory B-cell': '22.8', 'Exhausted memory B-cell': '22.0', 'Progenitor cell': '29.0', 'Memory T-reg': '52.5', 'Naive CD4 T-cell activated': '21.3', 'Naive CD8 T-cell activated': '25.8', 'Naive T-reg': '33.6'}
7DL2
{'Adipose Tissue': 36.53642857142857, 'Adrenal Gland': 30.212945736434108, 'Bladder': 52.913333333333334, 'Blood': 16.20875995694295, 'Blood Vessel': 48.646801498127346, 'Brain': 37.77624829674489, 'Breast': 44.235511982570806, 'Cervix Uteri': 78.39473684210526, 'Colon': 45.814069319640566, 'Esophagus': 41.6055017301038, 'Fallopian Tube': 71.01888888888888, 'Heart': 17.254009291521484, 'Kidney': 29.789089887640447, 'Liver': 17.942393805309734, 'Lung': 46.16290657439446, 'Muscle': 29.963922789539225, 'Nerve': 67.05111470113086, 'Ovary': 79.465, 'Pancreas': 20.655225609756094, 'Pituitary': 95.35706713780918, 'Prostate': 59.97763265306123, 'Salivary Gland': 43.391481481481485, 'Skin': 40.675754560530685, 'Small Intestine': 39.97299465240641, 'Spleen': 48.85937759336099, 'Stomach': 39.031671309192205, 'Testis': 85.90531855955679, 'Thyroid': 88.4304134762634, 'Uterus': 75.77908450704224, 'Vagina': 53.332051282051275}
null
null
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RING finger
null
null
null
RAN, RAE1, FBXO45, MYC, CPNE4, TSC2, ATP13A2, USP11, CPNE1, VWFA, RANGAP1]
MAP3K12, NMNAT2, TSC2, NR1D1
null
null
UBE2D3, UBE2D1, UBE2E1, UBE2L3
null
Thr, Ser
null
null
68.37425
0.484156
134
O75592
Q9BZQ4
29997255
UbiBrowser
MYCBP2
MMMCAATASPAAASSGLGGDGFYPAATFSSSPAPGALFMPVPDGSVAAAGLGLGLPAADSRGHYQLLLSGRALADRYRRIYTAALNDRDQGGGSAGHPASRNKKILNKKKLKRKQKSKSKVKTRSKSENLENTVIIPDIKLHSNPSAFNIYCNVRHCVLEWQKKEISLAAASKNSVQSGESDSDEEEESKEPPIKLPKIIEVGLCEVFELIKETRFSHPSLCLRSLQALLNVLQGQQPEGLQSEPPEVLESLFQLLLEITVRSTGMNDSTGQSLTALSCACLFSLVASWGETGRTLQAISAILTNNGSHACQTIQVPTILNSLQRSVQAVLVGKIQIQDWFSNGIKKAALMHKWPLKEISVDEDDQCLLQNDGFFLYLLCKDGLYKIGSGYSGTVRGHIYNSTSRIRNRKEKKSWLGYAQGYLLYRDVNNHSMTAIRISPETLEQDGTVMLPDCHTEGQNILFTDGEYINQIAASRDDGFVVRIFATSTEPVLQQELQLKLARKCLHACGISLFDLEKDLHIISTGFDEESAILGAGREFALMKTANGKIYYTGKYQSLGIKQGGPSAGKWVELPITKSPKIVHFSVGHDGSHALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSVISKDGELYMFGKDAIYSDSSSLVTDLKGHFVTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCGRDTGAMNQGGKGFGVENMATAMDEDLEEELDEKDEKSMMCPPGMHKWKLEQCMVCTVCGDCTGYGASCVSSGRPDRVPGGICGCGSGESGCAVCGCCKACARELDGQEARQRGILDAVKEMIPLDLLLAVPVPGVNIEEHLQLRQEEKRQRVIRRHRLEEGRGPLVFAGPIFMNHREQALARLRSHPAQLKHKRDKHKDGSGERGEKDASKITTYPPGSVRFDCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGASGDQTFLRIDEALINSHVLATSEIFASKHIIGLVPASISEPPPFKCLLINKVDGSCKTFNDSEQEDLQGFGVCLDPVYDVIWRFRPNTRELWCYNAVVADARLPSAADMQSRCSILSPELALPTGSRALTTRSHAALHILGCLDTLAAMQDLKMGVASTEEETQAVMKVYSKEDYSVVNRFESHGGGWGYSAHSVEAIRFSADTDILLGGLGLFGGRGEYTAKIKLFELGPDGGDHETDGDLLAETDVLAYDCAAREKYAMMFDEPVLLQAGWWYVAWARVSGPSSDCGSHGQASITTDDGVVFQFKSSKKSNNGTDVNAGQIPQLLYRLPTSDGSASKGKQQTSEPVHILKRSFARTVSVECFESLLSILHWSWTTLVLGVEELRGLKGFQFTATLLDLERLRFVGTCCLRLLRVYTCEIYPVSATGKAVVEETSKLAECIGKTRTLLRKILSEGVDHCMVKLDNDPQGYLSQPLSLLEAVLQECHNTFTACFHSFYPTPALQWACLCDLLNCLDQDIQEANFKTSSSRLLAAVMSALCHTSVKLTSIFPIAYDGEVLLRSIVKQVSTENDSTLVHRFPLLVAHMEKLSQSEENISGMTSFREVLEKMLVIVVLPVRNSLRRENELFSSHLVSNTCGLLASIVSELTASALGSEVDGLNSLHSVKASANRFTKTSQGRSWNTGNGSPDAICFSVDKPGIVVVGFSVYGGGGIHEYELEVLVDDSEHAGDSTHSHRWTSLELVKGTYTTDDSPSDIAEIRLDKVVPLKENVKYAVRLRNYGSRTANGDGGMTTVQCPDGVTFTFSTCSLSSNGTNQTRGQIPQILYYRSEFDGDLQSQLLSKANEEDKNCSRALSVVSTVVRASKDLLHRALAVDADDIPELLSSSSLFSMLLPLIIAYIGPVAAAIPKVAVEVFGLVQQLLPSVAILNQKYAPPAFNPNQSTDSTTGNQPEQGLSACTTSSHYAVIESEHPYKPACVMHYKVTFPECVRWMTIEFDPQCGTAQSEDVLRLLIPVRTVQNSGYGPKLTSVHENLNSWIELKKFSGSSGWPTMVLVLPGNEALFSLETASDYVKDDKASFYGFKCFAIGYEFSPGPDEGVIQLEKELANLGGVCAAALMKKDLALPIGNELEEDLEILEEAALQVCKTHSGILGKGLALSHSPTILEALEGNLPLQIQSNEQSFLDDFIACVPGSSGGRLARWLQPDSYADPQKTSLILNKDDIRCGWPTTITVQTKDQYGDVVHVPNMKVEVKAVPVSQKKMSLQQDQAKKPQRIPGSPAVTAASSNTDMTYGGLASPKLDVSYEPMIVKEARYIAITMMKVYENYSFEELRFASPTPKRPSENMLIRVNNDGTYCANWTPGAIGLYTLHVTIDGIEIDAGLEVKVKDPPKGMIPPGTQLVKPKSEPQPNKVRKFVAKDSAGLRIRSHPSLQSEQIGIVKVNGTITFIDEIHNDDGVWLRLNDETIKKYVPNMNGYTEAWCLSFNQHLGKSLLVPVDESKTNTDDFFKDINSCCPQEATMQEQDMPFLRGGPGMYKVVKTGPSGHNIRSCPNLRGIPIGMLVLGNKVKAVGEVTNSEGTWVQLDQNSMVEFCESDEGEAWSLARDRGGNQYLRHEDEQALLDQNSQTPPPSPFSVQAFNKGASCSAQGFDYGLGNSKGDRGNISTSSKPASTSGKSELSSKHSRSLKPDGRMSRTTADQKKPRGTESLSASESLILKSDAAKLRSDSHSRSLSPNHNTLQTLKSDGRMPSSSRAESPGPGSRLSSPKPKTLPANRSSPSGASSPRSSSPHDKNLPQKSTAPVKTKLDPPRERSKSDSYTLDPDTLRKKKMPLTEPLRGRSTSPKPKSVPKDSTDSPGSENRAPSPHVVQENLHSEVVEVCTSSTLKTNSLTDSTCDDSSEFKSVDEGSNKVHFSIGKAPLKDEQEMRASPKISRKCANRHTRPKKEKSSFLFKGDGSKPLEPAKQAMSPSVAECARAVFASFLWHEGIVHDAMACSSFLKFHPELSKEHAPIRSSLNSQQPTEEKETKLKNRHSLEISSALNMFNIAPHGPDISKMGSINKNKVLSMLKEPPLHEKCEDGKTETTFEMSMHNTMKSKSPLPLTLQHLVAFWEDISLATIKAASQNMIFPSPGSCAVLKKKECEKENKKSKKEKKKKEKAEVRPRGNLFGEMAQLAVGGPEKDTICELCGESHPYPVTYHMRQAHPGCGRYAGGQGYNSIGHFCGGWAGNCGDGGIGGSTWYLVCDRCREKYLREKQAAAREKVKQSRRKPMQVKTPRALPTMEAHQVIKANALFLLSLSSAAEPSILCYHPAKPFQSQLPSVKEGISEDLPVKMPCLYLQTLARHHHENFVGYQDDNLFQDEMRYLRSTSVPAPYISVTPDASPNVFEEPESNMKSMPPSLETSPITDTDLAKRTVFQRSYSVVASEYDKQHSILPARVKAIPRRRVNSGDTEVGSSLLRHPSPELSRLISAHSSLSKGERNFQWPVLAFVIQHHDLEGLEIAMKQALRKSACRVFAMEAFNWLLCNVIQTTSLHDILWHFVASLTPAPVEPEEEEDEENKTSKENSEQEKDTRVCEHPLSDIVIAGEAAHPLPHTFHRLLQTISDLMMSLPSGSSLQQMALRCWSLKFKQSDHQFLHQSNVFHHINNILSKSDDGDSEESFSISIQSGFEAMSQELCIVMCLKDLTSIVDIKTSSRPAMIGSLTDGSTETFWESGDEDKNKTKNITINCVKGINARYVSVHVDNSRDLGNKVTSMTFLTGKAVEDLCRIKQVDLDSRHIGWVTSELPGGDNHIIKIELKGPENTLRVRQVKVLGWKDGESTKIAGQISASVAQQRNCEAETLRVFRLITSQVFGKLISGDAEPTPEQEEKALLSSPEGEEKVYNATSDADLKEHMVGIIFSRSKLTNLQKQVCAHIVQAIRMEATRVREEWEHAISSKENANSQPNDEDASSDAYCFELLSMVLALSGSNVGRQYLAQQLTLLQDLFSLLHTASPRVQRQVTSLLRRVLPEVTPSRLASIIGVKSLPPADISDIIHSTEKGDWNKLGILDMFLGCIAKALTVQLKAKGTTITGTAGTTVGKGVTTVTLPMIFNSSYLRRGESHWWMKGSTPTQISEIIIKLIKDMAAGHLSEAWSRVTKNAIAETIIALTKMEEEFRSPVRCIATTRLWLALASLCVLDQDHVDRLSSGRWMGKDGQQKQMPMCDNHDDGETAAIILCNVCGNLCTDCDRFLHLHRRTKTHQRQVFKEEEEAIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREHTGKPTTSSSEACRFCGSRSGTELSAVGSVCSDADCQEYAKIACSKTHPCGHPCGGVKNEEHCLPCLHGCDKSATSLKQDADDMCMICFTEALSAAPAIQLDCSHIFHLQCCRRVLENRWLGPRITFGFISCPICKNKINHIVLKDLLDPIKELYEDVRRKALMRLEYEGLHKSEAITTPGVRFYNDPAGYAMNRYAYYVCYKCRKAYFGGEARCDAEAGRGDDYDPRELICGACSDVSRAQMCPKHGTDFLEYKCRYCCSVAVFFCFGTTHFCNACHDDFQRMTSIPKEELPHCPAGPKGKQLEGTECPLHVVHPPTGEEFALGCGVCRNAHTF
Homo sapiens
Nucleus, Cell projection, axon, Cytoplasm, cytoskeleton
Low tissue specificity
{'Ciliated cells': '36.2', 'Basal respiratory cells': '30.5', 'Club cells': '53.6', 'Ionocytes': '28.7', 'Mucus glandular cells': '71.8', 'Serous glandular cells': '103.1', 'Gastric mucus-secreting cells': '39.5', 'Proximal enterocytes': '12.1', 'Paneth cells': '13.8', 'Distal enterocytes': '12.7', 'Intestinal goblet cells': '15.7', 'Exocrine glandular cells': '-0.498', 'Basal prostatic cells': '49.1', 'Prostatic glandular cells': '119.8', 'Breast glandular cells': '-0.244', 'Breast myoepithelial cells': '-0.357', 'Glandular and luminal cells': '62.9', 'Secretory cells': '71.9', 'Basal keratinocytes': '139.0', 'Suprabasal keratinocytes': '233.8', 'Basal squamous epithelial cells': '80.2', 'Squamous epithelial cells': '134.8', 'Alveolar cells type 1': '0.015', 'Alveolar cells type 2': '-0.253', 'Salivary duct cells': '73.8', 'Ductal cells': '0.544', 'Hepatocytes': '0.502', 'Cholangiocytes': '28.6', 'Proximal tubular cells': '0.190', 'Distal tubular cells': '6.1', 'Collecting duct cells': '35.0', 'Mesothelial cells': '-0.242', 'Sertoli cells': '0.212', 'Granulosa cells': '37.2', 'Enteroendocrine cells': '31.9', 'Pancreatic endocrine cells': '13.6', 'Leydig cells': '0.251', 'Excitatory neurons': '411.2', 'Inhibitory neurons': '451.5', 'Cone photoreceptor cells': '66.3', 'Rod photoreceptor cells': '103.7', 'Bipolar cells': '219.1', 'Horizontal cells': '218.4', 'Astrocytes': '150.5', 'Oligodendrocyte precursor cells': '317.9', 'Oligodendrocytes': '197.8', 'Microglial cells': '270.2', 'Muller glia cells': '113.6', 'Schwann cells': '0.291', 'Spermatogonia': '0.467', 'Spermatocytes': '0.526', 'Early spermatids': '-0.048', 'Late spermatids': '-0.304', 'Oocytes': '43.4', 'Cytotrophoblasts': '46.7', 'Syncytiotrophoblasts': '43.2', 'Extravillous trophoblasts': '32.7', 'Endothelial cells': '94.0', 'Lymphatic endothelial cells': '55.4', 'Cardiomyocytes': '0.613', 'Skeletal myocytes': '-0.134', 'Smooth muscle cells': '93.8', 'Adipocytes': '90.1', 'Melanocytes': '0.263', 'Fibroblasts': '101.5', 'Peritubular cells': '0.295', 'Endometrial stromal cells': '58.3', 'Ovarian stromal cells': '84.2', 'Undifferentiated cells': '25.1', 'T-cells': '139.4', 'B-cells': '187.6', 'Plasma cells': '115.3', 'Nk-cells': '120.8', 'Granulocytes': '90.0', 'Monocytes': '158.5', 'Macrophages': '113.7', 'Hofbauer cells': '48.8', 'Kupffer cells': '88.8', 'Dendritic cells': '105.7', 'Langerhans cells': '0.350', 'Erythroid cells': '-0.073', 'Adipocytes (Subcutaneous)': '0.355', 'Adipocytes (Visceral)': '0.420', 'Breast glandular cells (progenitors)': '-0.257', 'Adipocytes (Breast)': '0.606', 'Colon enterocytes': '-0.140', 'Colon enteroendocrine cells': '0.306', 'Enteric glia cells': '-0.037', 'Mitotic cells (Colon)': '-0.065', 'Mitotic cells (Heart)': '0.494', 'Podocytes': '-0.114', 'Ascending Loop of Henle cells': '0.498', 'Intercalated cells': '-0.003', 'Cholangiocyte': '0.231', 'NK-cells (Liver)': '-0.278', 'Respiratory ciliated cells': '0.033', 'Mitotic cells (Lung)': '0.018', 'NK-cells (Lung)': '0.145', 'B-cells (Lung)': '0.092', 'Alpha cells': '0.363', 'Beta cells': '0.200', 'Prostate glandular cells': '-0.204', 'Prostate basal glandular cells': '0.017', 'Urothelial cells': '0.100', 'Keratinocyte (other)': '0.446', 'Keratinocyte (granular)': '0.334', 'Hair cortex cells': '-0.162', 'Inner root sheath cells': '-0.114', 'Outer root sheath cells': '-0.158', 'Sebaceous gland cells': '0.022', 'Eccrine sweat gland cells': '-0.293', 'Adipocytes (Skin)': '-0.162', 'Mitotic cells (Skin)': '0.202', 'Parietal cells': '-0.648', 'Chief cells': '-0.512', 'Gastric mucous cells': '-0.496', 'Gastric enteroendocrine cells': '-0.416', 'Mitotic cells (Stomach)': '-0.054', 'Parafollicular cells': '-0.017', 'Thyroid glandular cells': '0.232', 'Mitotic cells (Thyroid)': '0.223', 'Adrenal cortex cells': '0.673', 'Adrenal medulla cells': '0.215', 'Mitotic cells (Adrenal gland)': '0.411', 'Minor salivary glandular cells': '0.050', 'Minor salivary gland ductal cells': '-0.120', 'Minor salivary gland basal cells': '0.642', 'Mitotic cells (Minor salivary gland)': '0.672', 'Adipocytes (Minor salivary gland)': '0.370', 'Somatotropes': '0.320', 'Lactotropes': '0.078', 'Gonadotropes': '-0.024', 'Corticotropes': '-0.198', 'Thyrotropes': '0.046', 'Undifferentiated cells (Pituitary gland)': '0.134', 'Mitotic cells (Spleen)': '-0.072', 'Platelets': '-0.081', 'Erythrocytes': '-0.151', 'Hematopoietic stem cells': '-0.196', 'B-cells (Spleen)': '0.435', 'NK-cells (Spleen)': '0.203', 'Amygdala excitatory': '723.8', 'Cerebellar inhibitory': '645.2', 'Cge interneuron': '607.8', 'Deep-layer corticothalamic and 6b': '482.7', 'Deep-layer intratelencephalic': '668.6', 'Deep-layer near-projecting': '435.6', 'Eccentric medium spiny neuron': '671.6', 'Hippocampal ca1-3': '625.3', 'Hippocampal ca4': '594.4', 'Hippocampal dentate gyrus': '848.5', 'Lamp5-lhx6 and chandelier': '672.9', 'Lower rhombic lip': '636.4', 'Mammillary body': '648.1', 'Medium spiny neuron': '678.3', 'Mge interneuron': '687.8', 'Midbrain-derived inhibitory': '520.2', 'Miscellaneous': '559.6', 'Splatter': '577.7', 'Thalamic excitatory': '580.4', 'Upper rhombic lip': '508.1', 'Upper-layer intratelencephalic': '708.8', 'Astrocyte': '328.1', 'Bergmann glia': '352.2', 'Central nervous system macrophage': '849.4', 'Choroid plexus epithelial cell': '198.8', 'Committed oligodendrocyte precursor': '308.4', 'Ependymal cell': '837.2', 'Oligodendrocyte': '323.3', 'Oligodendrocyte precursor cell': '545.1', 'Endothelial cell': '331.6', 'Pericyte': '422.3', 'Vascular associated smooth muscle cell': '296.0', 'Fibroblast': '398.4', 'Leukocyte': '570.1', 'Basophil': '10.6', 'Eosinophil': '1.5', 'Neutrophil': '12.7', 'Classical monocyte': '41.8', 'Non-classical monocyte': '70.0', 'Intermediate monocyte': '29.9', 'T-reg': '23.7', 'GdT-cell': '1.9', 'MAIT T-cell': '21.0', 'Memory CD4 T-cell': '2.1', 'Naive CD4 T-cell': '143.1', 'Memory CD8 T-cell': '1.4', 'Naive CD8 T-cell': '114.2', 'Memory B-cell': '3.1', 'Naive B-cell': '170.9', 'Plasmacytoid DC': '11.7', 'Myeloid DC': '27.0', 'NK-cell': '86.3', 'Total PBMC': '20.1', 'Vd2 gdTCR': '23.1', 'Memory CD4 T-cell Th1\\/Th17': '109.1', 'Memory CD4 T-cell Th17': '108.8', 'Memory CD4 T-cell Th2': '118.9', 'Non-Vd2 gdTCR': '21.3', 'Memory CD4 T-cell Th1': '109.7', 'Memory CD4 T-cell TFH': '108.6', 'Terminal effector memory CD4 T-cell': '27.3', 'Central memory CD8 T-cell': '27.0', 'Effector memory CD8 T-cell': '28.1', 'Terminal effector memory CD8 T-cell': '21.8', 'Non-switched memory B-cell': '33.2', 'Plasmablast': '23.7', 'Switched memory B-cell': '33.2', 'Exhausted memory B-cell': '30.4', 'Progenitor cell': '17.8', 'Memory T-reg': '99.8', 'Naive CD4 T-cell activated': '109.3', 'Naive CD8 T-cell activated': '106.4', 'Naive T-reg': '129.1'}
5O6C, 6T7F
{'Adipose Tissue': 28.831866279069768, 'Adrenal Gland': 8.582108527131783, 'Bladder': 16.713809523809523, 'Blood': 11.589389235737352, 'Blood Vessel': 25.14011835205992, 'Brain': 16.480912187736564, 'Breast': 23.59864705882353, 'Cervix Uteri': 23.956315789473685, 'Colon': 12.481729139922978, 'Esophagus': 15.357815224913496, 'Fallopian Tube': 18.05777777777778, 'Heart': 6.1763454123112655, 'Kidney': 6.056449438202248, 'Liver': 3.7727477876106192, 'Lung': 16.354984429065745, 'Muscle': 7.081652552926526, 'Nerve': 26.11060743134087, 'Ovary': 26.55622222222222, 'Pancreas': 5.381393292682927, 'Pituitary': 15.922915194346292, 'Prostate': 13.769273469387755, 'Salivary Gland': 13.314876543209875, 'Skin': 32.49827860696517, 'Small Intestine': 16.56797860962567, 'Spleen': 21.57757676348548, 'Stomach': 9.303451253481894, 'Testis': 16.818326869806096, 'Thyroid': 17.588114854517613, 'Uterus': 19.83394366197183, 'Vagina': 22.515583333333332}
NMNAT2
MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQLYINASG
Homo sapiens
Golgi apparatus membrane, Cytoplasmic vesicle membrane, Cytoplasm, Cell projection, axon
Tissue enriched (brain)
{'Ciliated cells': '2.0', 'Basal respiratory cells': '0.5', 'Club cells': '0.1', 'Ionocytes': '0.4', 'Mucus glandular cells': '0.6', 'Serous glandular cells': '0.0', 'Gastric mucus-secreting cells': '0.0', 'Proximal enterocytes': '0.0', 'Paneth cells': '0.0', 'Distal enterocytes': '0.0', 'Intestinal goblet cells': '0.0', 'Exocrine glandular cells': '-0.375', 'Basal prostatic cells': '0.7', 'Prostatic glandular cells': '0.0', 'Breast glandular cells': '-0.287', 'Breast myoepithelial cells': '-0.164', 'Glandular and luminal cells': '2.9', 'Secretory cells': '1.1', 'Basal keratinocytes': '0.6', 'Suprabasal keratinocytes': '0.1', 'Basal squamous epithelial cells': '0.4', 'Squamous epithelial cells': '0.1', 'Alveolar cells type 1': '0.078', 'Alveolar cells type 2': '-0.211', 'Salivary duct cells': '6.4', 'Ductal cells': '0.397', 'Hepatocytes': '0.040', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.212', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.071', 'Sertoli cells': '0.635', 'Granulosa cells': '0.9', 'Enteroendocrine cells': '0.6', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.316', 'Excitatory neurons': '189.0', 'Inhibitory neurons': '254.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '2.1', 'Bipolar cells': '9.0', 'Horizontal cells': '27.7', 'Astrocytes': '3.7', 'Oligodendrocyte precursor cells': '92.4', 'Oligodendrocytes': '5.6', 'Microglial cells': '10.7', 'Muller glia cells': '0.4', 'Schwann cells': '0.580', 'Spermatogonia': '0.293', 'Spermatocytes': '0.034', 'Early spermatids': '-0.359', 'Late spermatids': '-0.319', 'Oocytes': '0.0', 'Cytotrophoblasts': '0.9', 'Syncytiotrophoblasts': '1.2', 'Extravillous trophoblasts': '15.5', 'Endothelial cells': '4.1', 'Lymphatic endothelial cells': '42.9', 'Cardiomyocytes': '0.533', 'Skeletal myocytes': '0.017', 'Smooth muscle cells': '10.0', 'Adipocytes': '19.7', 'Melanocytes': '0.213', 'Fibroblasts': '1.5', 'Peritubular cells': '0.208', 'Endometrial stromal cells': '0.2', 'Ovarian stromal cells': '0.1', 'Undifferentiated cells': '0.0', 'T-cells': '0.1', 'B-cells': '0.0', 'Plasma cells': '0.2', 'Nk-cells': '0.0', 'Granulocytes': '0.0', 'Monocytes': '0.0', 'Macrophages': '0.4', 'Hofbauer cells': '0.2', 'Kupffer cells': '1.1', 'Dendritic cells': '0.0', 'Langerhans cells': '0.149', 'Erythroid cells': '-0.046', 'Adipocytes (Subcutaneous)': '-0.119', 'Adipocytes (Visceral)': '-0.103', 'Breast glandular cells (progenitors)': '-0.275', 'Adipocytes (Breast)': '0.390', 'Colon enterocytes': '-0.034', 'Colon enteroendocrine cells': '0.630', 'Enteric glia cells': '0.308', 'Mitotic cells (Colon)': '-0.139', 'Mitotic cells (Heart)': '0.308', 'Podocytes': '-0.018', 'Ascending Loop of Henle cells': '0.099', 'Intercalated cells': '0.096', 'Cholangiocyte': '0.368', 'NK-cells (Liver)': '-0.027', 'Respiratory ciliated cells': '0.116', 'Mitotic cells (Lung)': '0.009', 'NK-cells (Lung)': '0.212', 'B-cells (Lung)': '0.205', 'Alpha cells': '0.657', 'Beta cells': '0.709', 'Prostate glandular cells': '-0.229', 'Prostate basal glandular cells': '-0.187', 'Urothelial cells': '-0.113', 'Keratinocyte (other)': '0.015', 'Keratinocyte (granular)': '-0.264', 'Hair cortex cells': '0.174', 'Inner root sheath cells': '0.246', 'Outer root sheath cells': '0.451', 'Sebaceous gland cells': '0.059', 'Eccrine sweat gland cells': '0.233', 'Adipocytes (Skin)': '0.113', 'Mitotic cells (Skin)': '0.309', 'Parietal cells': '-0.699', 'Chief cells': '-0.612', 'Gastric mucous cells': '-0.614', 'Gastric enteroendocrine cells': '-0.477', 'Mitotic cells (Stomach)': '-0.244', 'Parafollicular cells': '0.007', 'Thyroid glandular cells': '0.367', 'Mitotic cells (Thyroid)': '-0.064', 'Adrenal cortex cells': '0.279', 'Adrenal medulla cells': '0.560', 'Mitotic cells (Adrenal gland)': '0.060', 'Minor salivary glandular cells': '0.007', 'Minor salivary gland ductal cells': '-0.046', 'Minor salivary gland basal cells': '0.353', 'Mitotic cells (Minor salivary gland)': '0.392', 'Adipocytes (Minor salivary gland)': '0.301', 'Somatotropes': '0.361', 'Lactotropes': '0.323', 'Gonadotropes': '-0.098', 'Corticotropes': '0.271', 'Thyrotropes': '0.157', 'Undifferentiated cells (Pituitary gland)': '-0.354', 'Mitotic cells (Spleen)': '-0.073', 'Platelets': '0.047', 'Erythrocytes': '-0.163', 'Hematopoietic stem cells': '0.026', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.122', 'Amygdala excitatory': '372.9', 'Cerebellar inhibitory': '226.9', 'Cge interneuron': '418.9', 'Deep-layer corticothalamic and 6b': '315.7', 'Deep-layer intratelencephalic': '342.2', 'Deep-layer near-projecting': '267.6', 'Eccentric medium spiny neuron': '471.5', 'Hippocampal ca1-3': '329.1', 'Hippocampal ca4': '288.3', 'Hippocampal dentate gyrus': '272.6', 'Lamp5-lhx6 and chandelier': '367.5', 'Lower rhombic lip': '193.8', 'Mammillary body': '266.1', 'Medium spiny neuron': '414.1', 'Mge interneuron': '363.1', 'Midbrain-derived inhibitory': '190.0', 'Miscellaneous': '303.4', 'Splatter': '283.4', 'Thalamic excitatory': '279.3', 'Upper rhombic lip': '503.9', 'Upper-layer intratelencephalic': '331.6', 'Astrocyte': '15.0', 'Bergmann glia': '75.7', 'Central nervous system macrophage': '5.9', 'Choroid plexus epithelial cell': '2.6', 'Committed oligodendrocyte precursor': '44.2', 'Ependymal cell': '87.6', 'Oligodendrocyte': '5.4', 'Oligodendrocyte precursor cell': '166.0', 'Endothelial cell': '5.6', 'Pericyte': '5.1', 'Vascular associated smooth muscle cell': '162.2', 'Fibroblast': '47.5', 'Leukocyte': '4.3', 'Basophil': '0.1', 'Eosinophil': '0.0', 'Neutrophil': '0.2', 'Classical monocyte': '0.2', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '0.0', 'GdT-cell': '0.0', 'MAIT T-cell': '0.0', 'Memory CD4 T-cell': '0.0', 'Naive CD4 T-cell': '0.0', 'Memory CD8 T-cell': '0.0', 'Naive CD8 T-cell': '0.0', 'Memory B-cell': '0.0', 'Naive B-cell': '0.0', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.0', 'Total PBMC': '0.1', 'Vd2 gdTCR': '0.0', 'Memory CD4 T-cell TFH': '0.0', 'Memory CD4 T-cell Th2': '0.0', 'Memory CD4 T-cell Th17': '0.0', 'Memory CD4 T-cell Th1\\/Th17': '0.0', 'Non-Vd2 gdTCR': '0.0', 'Memory CD4 T-cell Th1': '0.0', 'Terminal effector memory CD4 T-cell': '0.0', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.0', 'Terminal effector memory CD8 T-cell': '0.0', 'Switched memory B-cell': '0.1', 'Plasmablast': '0.0', 'Non-switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.2', 'Progenitor cell': '0.1', 'Naive CD4 T-cell activated': '0.0', 'Naive CD8 T-cell activated': '0.0', 'Memory T-reg': '0.0', 'Naive T-reg': '0.0'}
null
{'Adipose Tissue': 6.24141096345515, 'Adrenal Gland': 1.543878449612403, 'Bladder': 1.200947619047619, 'Blood': 0.3269637556512378, 'Blood Vessel': 1.780982584269663, 'Brain': 46.385378728236184, 'Breast': 7.58057908496732, 'Cervix Uteri': 2.015315789473684, 'Colon': 2.8846612323491656, 'Esophagus': 1.304561972318339, 'Fallopian Tube': 1.834422222222222, 'Heart': 6.724729012775843, 'Kidney': 0.3925473033707864, 'Liver': 0.0597913407079646, 'Lung': 0.89035, 'Muscle': 0.3883472727272727, 'Nerve': 1.9401303715670437, 'Ovary': 0.9123721666666668, 'Pancreas': 0.6752867073170732, 'Pituitary': 30.90078798586573, 'Prostate': 0.4994902040816327, 'Salivary Gland': 0.7199080246913581, 'Skin': 3.351376340519624, 'Small Intestine': 1.5045497326203208, 'Spleen': 0.2466604564315352, 'Stomach': 1.5793857103064066, 'Testis': 21.95278393351801, 'Thyroid': 11.652087595712098, 'Uterus': 1.7201936619718308, 'Vagina': 1.723375}
null
null
[38.52, 48.68, 57.08, 64.17, 82.01, 89.88, 92.99, 94.31, 96.46, 97.9, 98.77, 98.77, 98.79, 98.52, 97.84, 97.84, 98.34, 97.62, 97.91, 98.61, 98.11, 97.46, 96.38, 97.85, 97.91, 96.48, 96.87, 98.3, 97.46, 96.63, 97.74, 97.88, 96.8, 96.99, 96.91, 96.37, 95.2, 93.91, 93.64, 93.39, 95.86, 96.14, 97.48, 95.97, 97.79, 98.62, 98.74, 98.85, 98.74, 98.63, 98.39, 98.37, 97.14, 96.56, 94.04, 84.67, 90.41, 91.1, 92.09, 95.97, 96.24, 97.04, 97.46, 97.8, 98.32, 98.54, 98.61, 98.69, 98.76, 98.79, 98.72, 98.71, 98.6, 98.45, 98.06, 97.22, 98.13, 97.59, 98.41, 98.62, 98.25, 98.66, 98.28, 98.18, 98.49, 98.44, 97.79, 97.06, 97.92, 96.89, 96.91, 97.58, 98.14, 97.72, 98.3, 98.36, 98.18, 98.56, 98.44, 97.88, 97.65, 96.73, 94.81, 93.25, 91.2, 86.82, 85.59, 83.34, 78.83, 76.33, 67.06, 59.87, 59.72, 57.75, 53.64, 52.02, 55.19, 46.75, 38.23, 41.42, 41.95, 39.85, 40.47, 42.03, 38.47, 43.35, 36.37, 31.44, 40.88, 39.0, 34.49, 37.47, 42.22, 40.71, 42.71, 42.82, 36.23, 38.12, 40.34, 37.1, 40.91, 38.92, 42.15, 34.99, 41.16, 37.68, 39.67, 36.39, 35.28, 36.95, 35.36, 36.97, 33.69, 32.97, 37.13, 33.43, 31.41, 35.54, 34.33, 33.32, 34.15, 38.37, 35.62, 36.52, 38.68, 39.06, 35.22, 38.64, 39.03, 42.36, 39.46, 34.82, 35.76, 34.05, 34.5, 39.51, 41.66, 47.18, 51.18, 50.03, 48.03, 43.38, 33.22, 40.14, 39.59, 38.59, 38.93, 47.84, 52.95, 61.8, 72.94, 85.22, 90.56, 94.48, 97.32, 98.45, 98.76, 98.75, 97.98, 95.68, 94.47, 94.43, 96.48, 97.03, 96.8, 96.67, 96.92, 96.03, 96.08, 94.4, 94.3, 95.42, 97.11, 96.54, 96.11, 97.48, 97.96, 97.69, 97.71, 98.08, 98.34, 97.38, 97.27, 96.55, 97.77, 97.94, 98.28, 98.33, 97.81, 96.66, 94.75, 90.13, 86.0, 83.68, 90.2, 93.78, 94.48, 94.87, 95.76, 95.74, 95.91, 95.35, 95.05, 95.26, 95.96, 96.92, 97.42, 96.8, 97.67, 97.33, 96.47, 95.97, 97.2, 97.79, 97.49, 96.82, 95.92, 88.44, 82.28, 80.01, 76.48, 82.7, 89.11, 90.78, 91.94, 89.52, 91.19, 93.29, 93.7, 95.22, 93.2, 92.78, 94.92, 94.8, 92.93, 93.04, 93.14, 91.0, 89.96, 85.63, 81.52, 84.42, 89.06, 93.13, 95.0, 94.63, 96.09, 97.18, 97.33, 97.16, 98.31, 98.36, 97.14, 97.16, 98.27, 97.22, 94.63, 96.84, 96.94, 94.45, 95.01, 92.7, 80.23, 73.09, 59.96, 46.13, 41.08]
[0.98, 0.91, 0.92, 0.77, 0.66, 0.46, 0.12, 0.24, 0.0, 0.11, 0.0, 0.0, 0.02, 0.17, 0.31, 0.17, 0.04, 0.03, 0.0, 0.02, 0.04, 0.35, 0.18, 0.2, 0.23, 0.31, 0.13, 0.0, 0.25, 0.1, 0.0, 0.26, 0.5, 0.22, 0.0, 0.41, 0.68, 0.3, 0.36, 0.63, 0.11, 0.36, 0.1, 0.48, 0.14, 0.01, 0.05, 0.01, 0.0, 0.0, 0.08, 0.1, 0.38, 0.6, 0.48, 0.69, 0.53, 0.87, 0.5, 0.23, 0.18, 0.43, 0.13, 0.72, 0.18, 0.0, 0.08, 0.3, 0.0, 0.0, 0.54, 0.26, 0.22, 0.08, 0.56, 0.99, 0.32, 0.95, 0.14, 0.06, 0.61, 0.21, 0.21, 0.32, 0.22, 0.03, 0.08, 0.74, 0.3, 0.91, 0.66, 0.5, 0.24, 0.37, 0.17, 0.03, 0.27, 0.0, 0.0, 0.36, 0.23, 0.04, 0.26, 0.45, 0.34, 0.13, 0.58, 0.56, 0.52, 0.35, 0.41, 0.53, 0.58, 0.57, 0.53, 0.7, 0.56, 0.73, 0.73, 0.78, 0.83, 0.89, 0.85, 0.83, 0.94, 0.88, 0.8, 0.98, 0.94, 0.99, 0.98, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 0.96, 1.0, 0.95, 0.99, 1.0, 0.97, 0.9, 1.0, 0.96, 0.82, 0.9, 0.79, 0.92, 0.86, 0.88, 0.95, 0.87, 0.89, 0.91, 0.84, 0.61, 0.88, 0.64, 0.73, 0.93, 0.73, 0.86, 0.84, 0.85, 0.72, 0.84, 0.6, 0.69, 0.92, 0.65, 0.5, 0.3, 0.26, 0.05, 0.01, 0.0, 0.01, 0.04, 0.11, 0.05, 0.55, 0.27, 0.0, 0.57, 0.12, 0.04, 0.32, 0.54, 0.92, 0.88, 0.64, 0.22, 0.58, 0.65, 0.55, 0.23, 0.04, 0.36, 0.25, 0.0, 0.0, 0.35, 0.66, 0.03, 0.0, 0.0, 0.0, 0.0, 0.05, 0.08, 0.27, 0.65, 0.67, 0.28, 0.51, 0.09, 0.41, 0.65, 0.1, 0.04, 0.49, 0.63, 0.1, 0.69, 0.1, 0.0, 0.49, 0.74, 0.31, 0.41, 0.94, 0.18, 0.07, 0.1, 0.1, 0.01, 0.65, 0.41, 0.57, 0.46, 0.83, 0.2, 0.72, 0.25, 0.09, 0.48, 0.06, 0.2, 0.16, 0.52, 0.42, 0.0, 0.2, 0.44, 0.05, 0.12, 0.33, 0.77, 0.77, 0.39, 0.63, 0.54, 0.09, 0.43, 0.52, 0.27, 0.02, 0.29, 0.54, 0.35, 0.01, 0.05, 0.5, 0.16, 0.0, 0.48, 0.84, 0.32, 0.66, 0.11, 0.06, 0.4, 0.95, 0.48, 0.9, 0.77]
RING finger
null
null
null
RAN, RAE1, FBXO45, MYC, CPNE4, TSC2, ATP13A2, USP11, CPNE1, VWFA, RANGAP1]
MAP3K12, NMNAT2, TSC2, NR1D1
null
null
UBE2D3, UBE2D1, UBE2E1, UBE2L3
null
Thr, Ser
null
null
79.870945
0.463029
2,358
O75717
Q15555
32426268
UbiBrowser
WDHD1
MPATRKPMRYGHTEGHTEVCFDDSGSFIVTCGSDGDVRIWEDLDDDDPKFINVGEKAYSCALKSGKLVTAVSNNTIQVHTFPEGVPDGILTRFTTNANHVVFNGDGTKIAAGSSDFLVKIVDVMDSSQQKTFRGHDAPVLSLSFDPKDIFLASASCDGSVRVWQISDQTCAISWPLLQKCNDVINAKSICRLAWQPKSGKLLAIPVEKSVKLYRRESWSHQFDLSDNFISQTLNIVTWSPCGQYLAAGSINGLIIVWNVETKDCMERVKHEKGYAICGLAWHPTCGRISYTDAEGNLGLLENVCDPSGKTSSSKVSSRVEKDYNDLFDGDDMSNAGDFLNDNAVEIPSFSKGIINDDEDDEDLMMASGRPRQRSHILEDDENSVDISMLKTGSSLLKEEEEDGQEGSIHNLPLVTSQRPFYDGPMPTPRQKPFQSGSTPLHLTHRFMVWNSIGIIRCYNDEQDNAIDVEFHDTSIHHATHLSNTLNYTIADLSHEAILLACESTDELASKLHCLHFSSWDSSKEWIIDLPQNEDIEAICLGQGWAAAATSALLLRLFTIGGVQKEVFSLAGPVVSMAGHGEQLFIVYHRGTGFDGDQCLGVQLLELGKKKKQILHGDPLPLTRKSYLAWIGFSAEGTPCYVDSEGIVRMLNRGLGNTWTPICNTREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAILSFKLPYCQIATEKGQMEEQFWRSVIFHNHLDYLAKNGYEYEESTKNQATKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVNLAIKYASRSRKLILAQKLSELAVEKAAELTATQVEEEEEEEDFRKKLNAGYSNTATEWSQPRFRNQVEEDAEDSGEADDEEKPEIHKPGQNSFSKSTNSSDVSAKSGAVTFSSQGRVNPFKVSASSKEPAMSMNSARSTNILDNMGKSSKKSTALSRTTNNEKSPIIKPLIPKPKPKQASAASYFQKRNSQTNKTEEVKEENLKNVLSETPAICPPQNTENQRPKTGFQMWLEENRSNILSDNPDFSDEADIIKEGMIRFRVLSTEERKVWANKAKGETASEGTEAKKRKRVVDESDETENQEEKAKENLNLSKKQKPLDFSTNQKLSAFAFKQE
Homo sapiens
Nucleus, nucleoplasm
Tissue enhanced (lymphoid)
{'Ciliated cells': '2.4', 'Basal respiratory cells': '3.1', 'Club cells': '1.7', 'Ionocytes': '2.6', 'Mucus glandular cells': '1.1', 'Serous glandular cells': '4.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '0.4', 'Paneth cells': '0.2', 'Distal enterocytes': '0.9', 'Intestinal goblet cells': '2.8', 'Exocrine glandular cells': '-0.547', 'Basal prostatic cells': '1.2', 'Prostatic glandular cells': '0.8', 'Breast glandular cells': '0.414', 'Breast myoepithelial cells': '0.451', 'Glandular and luminal cells': '2.5', 'Secretory cells': '2.9', 'Basal keratinocytes': '5.8', 'Suprabasal keratinocytes': '2.5', 'Basal squamous epithelial cells': '4.2', 'Squamous epithelial cells': '5.8', 'Alveolar cells type 1': '-0.213', 'Alveolar cells type 2': '0.162', 'Salivary duct cells': '2.6', 'Ductal cells': '0.524', 'Hepatocytes': '0.152', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.133', 'Distal tubular cells': '3.1', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.288', 'Sertoli cells': '0.314', 'Granulosa cells': '4.0', 'Enteroendocrine cells': '1.0', 'Pancreatic endocrine cells': '1.7', 'Leydig cells': '0.315', 'Excitatory neurons': '9.9', 'Inhibitory neurons': '6.2', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '2.3', 'Bipolar cells': '3.4', 'Horizontal cells': '0.6', 'Astrocytes': '3.7', 'Oligodendrocyte precursor cells': '4.2', 'Oligodendrocytes': '9.4', 'Microglial cells': '5.4', 'Muller glia cells': '1.4', 'Schwann cells': '0.042', 'Spermatogonia': '0.735', 'Spermatocytes': '0.763', 'Early spermatids': '-0.059', 'Late spermatids': '-0.383', 'Oocytes': '12.5', 'Cytotrophoblasts': '9.1', 'Syncytiotrophoblasts': '2.2', 'Extravillous trophoblasts': '8.0', 'Endothelial cells': '2.2', 'Lymphatic endothelial cells': '1.3', 'Cardiomyocytes': '0.464', 'Skeletal myocytes': '0.008', 'Smooth muscle cells': '2.2', 'Adipocytes': '2.7', 'Melanocytes': '0.396', 'Fibroblasts': '2.4', 'Peritubular cells': '0.229', 'Endometrial stromal cells': '3.0', 'Ovarian stromal cells': '1.7', 'Undifferentiated cells': '10.3', 'T-cells': '3.1', 'B-cells': '4.2', 'Plasma cells': '8.6', 'Nk-cells': '2.6', 'Granulocytes': '1.5', 'Monocytes': '1.5', 'Macrophages': '2.8', 'Hofbauer cells': '3.2', 'Kupffer cells': '2.2', 'Dendritic cells': '2.6', 'Langerhans cells': '0.314', 'Erythroid cells': '-0.015', 'Adipocytes (Subcutaneous)': '-0.311', 'Adipocytes (Visceral)': '-0.357', 'Breast glandular cells (progenitors)': '0.314', 'Adipocytes (Breast)': '-0.397', 'Colon enterocytes': '0.029', 'Colon enteroendocrine cells': '0.112', 'Enteric glia cells': '0.038', 'Mitotic cells (Colon)': '0.319', 'Mitotic cells (Heart)': '0.543', 'Podocytes': '-0.162', 'Ascending Loop of Henle cells': '0.493', 'Intercalated cells': '-0.011', 'Cholangiocyte': '0.344', 'NK-cells (Liver)': '-0.156', 'Respiratory ciliated cells': '0.028', 'Mitotic cells (Lung)': '0.571', 'NK-cells (Lung)': '-0.122', 'B-cells (Lung)': '-0.060', 'Alpha cells': '0.326', 'Beta cells': '0.123', 'Prostate glandular cells': '-0.284', 'Prostate basal glandular cells': '0.222', 'Urothelial cells': '0.339', 'Keratinocyte (other)': '0.321', 'Keratinocyte (granular)': '-0.321', 'Hair cortex cells': '0.100', 'Inner root sheath cells': '0.201', 'Outer root sheath cells': '0.333', 'Sebaceous gland cells': '0.151', 'Eccrine sweat gland cells': '0.023', 'Adipocytes (Skin)': '-0.197', 'Mitotic cells (Skin)': '0.680', 'Parietal cells': '-0.436', 'Chief cells': '-0.372', 'Gastric mucous cells': '0.049', 'Gastric enteroendocrine cells': '-0.182', 'Mitotic cells (Stomach)': '0.557', 'Parafollicular cells': '0.062', 'Thyroid glandular cells': '0.089', 'Mitotic cells (Thyroid)': '0.338', 'Adrenal cortex cells': '0.447', 'Adrenal medulla cells': '0.056', 'Mitotic cells (Adrenal gland)': '0.512', 'Minor salivary glandular cells': '0.317', 'Minor salivary gland ductal cells': '-0.160', 'Minor salivary gland basal cells': '0.725', 'Mitotic cells (Minor salivary gland)': '0.791', 'Adipocytes (Minor salivary gland)': '0.263', 'Somatotropes': '-0.278', 'Lactotropes': '-0.168', 'Gonadotropes': '0.044', 'Corticotropes': '-0.192', 'Thyrotropes': '-0.005', 'Undifferentiated cells (Pituitary gland)': '0.329', 'Mitotic cells (Spleen)': '0.679', 'Platelets': '0.044', 'Erythrocytes': '0.182', 'Hematopoietic stem cells': '0.115', 'B-cells (Spleen)': '0.158', 'NK-cells (Spleen)': '0.026', 'Amygdala excitatory': '17.2', 'Cerebellar inhibitory': '10.2', 'Cge interneuron': '11.0', 'Deep-layer corticothalamic and 6b': '17.4', 'Deep-layer intratelencephalic': '15.4', 'Deep-layer near-projecting': '12.6', 'Eccentric medium spiny neuron': '21.6', 'Hippocampal ca1-3': '17.1', 'Hippocampal ca4': '14.0', 'Hippocampal dentate gyrus': '22.4', 'Lamp5-lhx6 and chandelier': '10.9', 'Lower rhombic lip': '10.7', 'Mammillary body': '9.8', 'Medium spiny neuron': '24.0', 'Mge interneuron': '9.9', 'Midbrain-derived inhibitory': '9.1', 'Miscellaneous': '16.0', 'Splatter': '9.3', 'Thalamic excitatory': '12.4', 'Upper rhombic lip': '11.5', 'Upper-layer intratelencephalic': '16.3', 'Astrocyte': '8.5', 'Bergmann glia': '9.4', 'Central nervous system macrophage': '11.7', 'Choroid plexus epithelial cell': '5.5', 'Committed oligodendrocyte precursor': '9.9', 'Ependymal cell': '7.5', 'Oligodendrocyte': '14.0', 'Oligodendrocyte precursor cell': '9.0', 'Endothelial cell': '6.2', 'Pericyte': '4.3', 'Vascular associated smooth muscle cell': '3.9', 'Fibroblast': '5.6', 'Leukocyte': '10.2', 'Basophil': '3.4', 'Eosinophil': '0.6', 'Neutrophil': '0.9', 'Classical monocyte': '0.5', 'Non-classical monocyte': '1.3', 'Intermediate monocyte': '3.3', 'T-reg': '10.7', 'GdT-cell': '0.9', 'MAIT T-cell': '5.4', 'Memory CD4 T-cell': '1.1', 'Naive CD4 T-cell': '3.9', 'Memory CD8 T-cell': '1.3', 'Naive CD8 T-cell': '3.5', 'Memory B-cell': '1.2', 'Naive B-cell': '5.1', 'Plasmacytoid DC': '4.5', 'Myeloid DC': '1.2', 'NK-cell': '5.0', 'Total PBMC': '2.9', 'Vd2 gdTCR': '4.2', 'Memory CD4 T-cell Th1\\/Th17': '3.5', 'Memory CD4 T-cell Th17': '3.3', 'Memory CD4 T-cell Th2': '3.4', 'Non-Vd2 gdTCR': '4.9', 'Memory CD4 T-cell Th1': '3.3', 'Memory CD4 T-cell TFH': '2.9', 'Terminal effector memory CD4 T-cell': '9.2', 'Central memory CD8 T-cell': '6.4', 'Effector memory CD8 T-cell': '7.5', 'Terminal effector memory CD8 T-cell': '6.3', 'Non-switched memory B-cell': '6.8', 'Plasmablast': '14.6', 'Switched memory B-cell': '3.7', 'Exhausted memory B-cell': '6.8', 'Progenitor cell': '11.1', 'Memory T-reg': '4.3', 'Naive CD4 T-cell activated': '7.3', 'Naive CD8 T-cell activated': '5.3', 'Naive T-reg': '3.9'}
2D7L, 5GVA, 5GVB, 5OGS, 6XTY, 7PFO, 7PLO, 8B9D
{'Adipose Tissue': 1.6275238621262458, 'Adrenal Gland': 1.177625968992248, 'Bladder': 1.522095238095238, 'Blood': 4.658325041980625, 'Blood Vessel': 1.2865683146067417, 'Brain': 1.1499497047691143, 'Breast': 1.7335008714596951, 'Cervix Uteri': 2.351684210526316, 'Colon': 1.3807397946084723, 'Esophagus': 2.0458381314878893, 'Fallopian Tube': 2.5835555555555554, 'Heart': 0.4865351103368176, 'Kidney': 0.7071224719101123, 'Liver': 0.357617610619469, 'Lung': 1.8880449826989616, 'Muscle': 0.4692139227895392, 'Nerve': 2.2514588045234247, 'Ovary': 2.247271666666667, 'Pancreas': 0.381781006097561, 'Pituitary': 0.9843024734982332, 'Prostate': 1.1874559183673468, 'Salivary Gland': 1.4253722222222225, 'Skin': 5.277421724709785, 'Small Intestine': 1.8943796791443852, 'Spleen': 2.192741908713693, 'Stomach': 1.0815935933147631, 'Testis': 7.00828808864266, 'Thyroid': 1.1931758039816234, 'Uterus': 2.8056669014084505, 'Vagina': 2.6626955128205125}
MAPRE2
MPGPTQTLSPNGENNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASKSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY
Homo sapiens
Cytoplasm, cytoskeleton
Tissue enhanced (brain)
{'Ciliated cells': '6.6', 'Basal respiratory cells': '1.7', 'Club cells': '5.4', 'Ionocytes': '1.8', 'Mucus glandular cells': '13.8', 'Serous glandular cells': '14.3', 'Gastric mucus-secreting cells': '43.6', 'Proximal enterocytes': '10.2', 'Paneth cells': '12.7', 'Distal enterocytes': '16.6', 'Intestinal goblet cells': '24.2', 'Exocrine glandular cells': '-0.513', 'Basal prostatic cells': '4.7', 'Prostatic glandular cells': '3.5', 'Breast glandular cells': '0.199', 'Breast myoepithelial cells': '0.414', 'Glandular and luminal cells': '11.4', 'Secretory cells': '2.5', 'Basal keratinocytes': '14.7', 'Suprabasal keratinocytes': '21.0', 'Basal squamous epithelial cells': '28.8', 'Squamous epithelial cells': '5.6', 'Alveolar cells type 1': '0.310', 'Alveolar cells type 2': '-0.330', 'Salivary duct cells': '13.5', 'Ductal cells': '0.558', 'Hepatocytes': '0.346', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.004', 'Distal tubular cells': '3.1', 'Collecting duct cells': '3.9', 'Mesothelial cells': '0.350', 'Sertoli cells': '0.490', 'Granulosa cells': '7.2', 'Enteroendocrine cells': '20.5', 'Pancreatic endocrine cells': '6.8', 'Leydig cells': '0.671', 'Excitatory neurons': '157.8', 'Inhibitory neurons': '135.7', 'Cone photoreceptor cells': '28.9', 'Rod photoreceptor cells': '9.9', 'Bipolar cells': '92.1', 'Horizontal cells': '51.0', 'Astrocytes': '99.4', 'Oligodendrocyte precursor cells': '91.5', 'Oligodendrocytes': '405.8', 'Microglial cells': '67.1', 'Muller glia cells': '37.6', 'Schwann cells': '0.154', 'Spermatogonia': '0.595', 'Spermatocytes': '0.135', 'Early spermatids': '-0.446', 'Late spermatids': '-0.643', 'Oocytes': '38.2', 'Cytotrophoblasts': '0.4', 'Syncytiotrophoblasts': '0.4', 'Extravillous trophoblasts': '10.9', 'Endothelial cells': '25.3', 'Lymphatic endothelial cells': '31.7', 'Cardiomyocytes': '0.708', 'Skeletal myocytes': '0.451', 'Smooth muscle cells': '64.2', 'Adipocytes': '26.5', 'Melanocytes': '0.217', 'Fibroblasts': '25.1', 'Peritubular cells': '0.707', 'Endometrial stromal cells': '12.0', 'Ovarian stromal cells': '10.9', 'Undifferentiated cells': '10.9', 'T-cells': '71.0', 'B-cells': '70.1', 'Plasma cells': '17.6', 'Nk-cells': '117.7', 'Granulocytes': '22.5', 'Monocytes': '74.6', 'Macrophages': '42.5', 'Hofbauer cells': '27.1', 'Kupffer cells': '37.3', 'Dendritic cells': '61.0', 'Langerhans cells': '0.333', 'Erythroid cells': '0.096', 'Adipocytes (Subcutaneous)': '-0.508', 'Adipocytes (Visceral)': '-0.399', 'Breast glandular cells (progenitors)': '0.213', 'Adipocytes (Breast)': '-0.298', 'Colon enterocytes': '-0.163', 'Colon enteroendocrine cells': '0.475', 'Enteric glia cells': '0.796', 'Mitotic cells (Colon)': '-0.162', 'Mitotic cells (Heart)': '0.461', 'Podocytes': '0.017', 'Ascending Loop of Henle cells': '0.584', 'Intercalated cells': '0.132', 'Cholangiocyte': '0.424', 'NK-cells (Liver)': '-0.153', 'Respiratory ciliated cells': '0.071', 'Mitotic cells (Lung)': '-0.061', 'NK-cells (Lung)': '0.483', 'B-cells (Lung)': '0.126', 'Alpha cells': '0.506', 'Beta cells': '0.324', 'Prostate glandular cells': '-0.421', 'Prostate basal glandular cells': '-0.274', 'Urothelial cells': '-0.205', 'Keratinocyte (other)': '0.290', 'Keratinocyte (granular)': '0.135', 'Hair cortex cells': '0.020', 'Inner root sheath cells': '-0.003', 'Outer root sheath cells': '0.062', 'Sebaceous gland cells': '-0.081', 'Eccrine sweat gland cells': '0.073', 'Adipocytes (Skin)': '-0.133', 'Mitotic cells (Skin)': '0.269', 'Parietal cells': '-0.539', 'Chief cells': '-0.532', 'Gastric mucous cells': '-0.322', 'Gastric enteroendocrine cells': '-0.355', 'Mitotic cells (Stomach)': '0.087', 'Parafollicular cells': '0.045', 'Thyroid glandular cells': '0.338', 'Mitotic cells (Thyroid)': '0.205', 'Adrenal cortex cells': '0.617', 'Adrenal medulla cells': '0.006', 'Mitotic cells (Adrenal gland)': '0.309', 'Minor salivary glandular cells': '0.260', 'Minor salivary gland ductal cells': '0.172', 'Minor salivary gland basal cells': '0.065', 'Mitotic cells (Minor salivary gland)': '0.183', 'Adipocytes (Minor salivary gland)': '0.123', 'Somatotropes': '-0.306', 'Lactotropes': '0.101', 'Gonadotropes': '0.116', 'Corticotropes': '0.288', 'Thyrotropes': '0.471', 'Undifferentiated cells (Pituitary gland)': '0.128', 'Mitotic cells (Spleen)': '-0.133', 'Platelets': '-0.083', 'Erythrocytes': '-0.212', 'Hematopoietic stem cells': '-0.185', 'B-cells (Spleen)': '0.409', 'NK-cells (Spleen)': '0.337', 'Amygdala excitatory': '295.0', 'Cerebellar inhibitory': '201.5', 'Cge interneuron': '177.4', 'Deep-layer corticothalamic and 6b': '259.7', 'Deep-layer intratelencephalic': '272.0', 'Deep-layer near-projecting': '326.0', 'Eccentric medium spiny neuron': '226.1', 'Hippocampal ca1-3': '266.4', 'Hippocampal ca4': '242.2', 'Hippocampal dentate gyrus': '244.0', 'Lamp5-lhx6 and chandelier': '194.2', 'Lower rhombic lip': '229.5', 'Mammillary body': '253.7', 'Medium spiny neuron': '235.0', 'Mge interneuron': '222.1', 'Midbrain-derived inhibitory': '310.9', 'Miscellaneous': '259.5', 'Splatter': '212.1', 'Thalamic excitatory': '300.9', 'Upper rhombic lip': '215.0', 'Upper-layer intratelencephalic': '258.1', 'Astrocyte': '215.7', 'Bergmann glia': '179.6', 'Central nervous system macrophage': '186.1', 'Choroid plexus epithelial cell': '135.1', 'Committed oligodendrocyte precursor': '243.3', 'Ependymal cell': '78.5', 'Oligodendrocyte': '634.4', 'Oligodendrocyte precursor cell': '170.3', 'Endothelial cell': '73.3', 'Pericyte': '182.4', 'Vascular associated smooth muscle cell': '454.0', 'Fibroblast': '128.6', 'Leukocyte': '227.6', 'Basophil': '121.9', 'Eosinophil': '46.8', 'Neutrophil': '56.0', 'Classical monocyte': '36.1', 'Non-classical monocyte': '58.0', 'Intermediate monocyte': '103.9', 'T-reg': '91.0', 'GdT-cell': '63.9', 'MAIT T-cell': '129.6', 'Memory CD4 T-cell': '44.5', 'Naive CD4 T-cell': '86.2', 'Memory CD8 T-cell': '58.3', 'Naive CD8 T-cell': '80.1', 'Memory B-cell': '61.1', 'Naive B-cell': '68.7', 'Plasmacytoid DC': '214.6', 'Myeloid DC': '87.5', 'NK-cell': '184.2', 'Total PBMC': '136.0', 'Vd2 gdTCR': '154.0', 'Memory CD4 T-cell Th1\\/Th17': '71.5', 'Memory CD4 T-cell Th17': '64.6', 'Memory CD4 T-cell Th2': '67.8', 'Non-Vd2 gdTCR': '244.2', 'Memory CD4 T-cell Th1': '74.0', 'Memory CD4 T-cell TFH': '76.9', 'Terminal effector memory CD4 T-cell': '158.9', 'Central memory CD8 T-cell': '121.0', 'Effector memory CD8 T-cell': '161.0', 'Terminal effector memory CD8 T-cell': '194.5', 'Non-switched memory B-cell': '148.5', 'Plasmablast': '32.7', 'Switched memory B-cell': '109.8', 'Exhausted memory B-cell': '115.2', 'Progenitor cell': '182.7', 'Memory T-reg': '70.9', 'Naive CD4 T-cell activated': '251.6', 'Naive CD8 T-cell activated': '265.3', 'Naive T-reg': '76.3'}
null
{'Adipose Tissue': 25.14169019933555, 'Adrenal Gland': 46.13066279069767, 'Bladder': 39.17142857142857, 'Blood': 17.552686975242196, 'Blood Vessel': 64.41851685393259, 'Brain': 68.20622558667677, 'Breast': 21.175727668845315, 'Cervix Uteri': 25.45263157894737, 'Colon': 25.586857509627727, 'Esophagus': 20.440526643598616, 'Fallopian Tube': 22.43911111111111, 'Heart': 37.16147224157956, 'Kidney': 10.065662921348316, 'Liver': 9.45779203539823, 'Lung': 33.463494809688584, 'Muscle': 24.64939601494396, 'Nerve': 39.520468497576736, 'Ovary': 29.45895, 'Pancreas': 5.691396341463415, 'Pituitary': 25.08773851590106, 'Prostate': 19.826595918367342, 'Salivary Gland': 14.101395061728397, 'Skin': 23.72639303482587, 'Small Intestine': 24.37651336898396, 'Spleen': 24.69583817427386, 'Stomach': 19.463777158774377, 'Testis': 7.488094182825486, 'Thyroid': 25.444313935681468, 'Uterus': 22.365422535211263, 'Vagina': 23.30874358974359}
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[43.63, 49.6, 47.95, 46.15, 37.28, 40.38, 38.91, 35.06, 40.1, 36.49, 38.95, 36.39, 40.62, 37.98, 43.03, 42.36, 40.5, 41.41, 40.0, 33.89, 45.61, 48.88, 50.71, 44.56, 43.11, 41.28, 43.95, 42.85, 38.88, 47.13, 38.4, 41.2, 35.94, 32.41, 31.4, 30.02, 30.91, 33.42, 37.27, 40.63, 43.46, 54.11, 63.02, 84.76, 93.2, 94.11, 94.52, 92.91, 88.75, 75.07, 70.13, 67.39, 65.28, 54.91, 58.72, 66.07, 77.96, 86.73, 90.93, 91.28, 93.25, 95.24, 95.49, 95.95, 95.85, 96.22, 96.73, 94.73, 94.46, 94.04, 91.91, 90.8, 89.49, 91.66, 93.55, 93.74, 93.57, 95.83, 95.66, 95.83, 97.24, 97.52, 96.77, 97.75, 96.9, 97.37, 98.41, 97.86, 96.4, 97.67, 97.29, 95.58, 94.87, 95.7, 94.67, 92.7, 90.72, 94.07, 96.02, 93.95, 94.04, 92.98, 95.66, 96.39, 95.22, 94.03, 92.29, 93.46, 93.2, 93.83, 95.44, 96.45, 97.71, 98.28, 98.14, 98.44, 98.38, 98.61, 98.28, 98.29, 98.46, 98.1, 97.27, 96.8, 97.15, 95.45, 94.83, 94.84, 95.0, 96.39, 94.52, 96.9, 96.94, 97.76, 97.18, 97.99, 96.95, 97.08, 98.02, 97.57, 96.19, 93.93, 92.96, 94.43, 93.45, 95.84, 96.82, 95.22, 93.96, 97.0, 96.75, 93.7, 95.68, 97.08, 95.19, 93.33, 95.73, 96.09, 93.83, 93.47, 95.28, 94.96, 91.33, 91.43, 90.67, 93.19, 94.29, 93.45, 92.43, 90.69, 91.65, 91.5, 90.39, 83.3, 71.9, 74.17, 70.16, 68.7, 74.29, 73.2, 74.1, 77.25, 69.68, 62.27, 56.46, 54.94, 52.27, 51.42, 48.78, 41.41, 46.25, 46.58, 46.3, 43.88, 44.16, 49.82, 46.24, 46.23, 45.7, 50.77, 48.16, 53.7, 46.8, 47.57, 47.68, 49.04, 51.2, 58.68, 61.31, 49.95, 55.42, 51.99, 58.21, 50.88, 51.09, 53.95, 54.1, 53.31, 52.37, 49.46, 51.69, 50.89, 48.27, 47.18, 47.49, 45.38, 39.92, 49.17, 42.92, 51.4, 52.79, 54.5, 55.81, 59.21, 60.14, 71.25, 78.77, 81.53, 82.52, 85.02, 86.53, 87.58, 86.75, 89.54, 90.49, 86.99, 90.46, 90.56, 89.95, 87.16, 91.65, 89.54, 86.84, 91.37, 91.07, 87.55, 87.97, 91.17, 91.05, 86.11, 91.21, 93.83, 91.72, 93.4, 95.47, 94.25, 93.87, 95.91, 94.98, 95.74, 95.11, 95.46, 93.55, 94.32, 91.88, 91.44, 91.97, 90.17, 89.47, 87.2, 86.76, 78.25, 69.53, 68.26, 69.65, 70.5, 82.95, 87.23, 87.56, 88.95, 87.11, 88.65, 90.04, 87.69, 90.19, 90.94, 91.15, 90.6, 90.07, 80.68, 70.63, 58.82, 56.51, 52.08, 44.81, 40.0, 42.18, 39.46, 39.76, 41.75, 37.47, 42.05, 37.13, 39.72, 36.16, 41.09, 38.73, 36.61, 39.34, 37.81, 49.34, 40.55, 39.56, 44.44, 39.91, 49.76, 44.19]
[0.99, 1.0, 0.91, 0.94, 0.91, 0.94, 0.89, 0.94, 0.9, 0.94, 0.77, 0.94, 0.72, 0.71, 0.76, 0.7, 0.62, 0.61, 0.62, 0.82, 0.49, 1.0, 0.84, 0.72, 0.49, 0.61, 0.58, 0.59, 0.57, 0.62, 0.79, 0.73, 0.92, 0.9, 0.96, 0.98, 0.92, 0.97, 0.82, 0.71, 0.8, 0.31, 0.23, 0.58, 0.1, 0.41, 0.28, 0.18, 0.69, 0.68, 0.64, 0.67, 0.74, 0.94, 0.61, 0.92, 0.71, 0.31, 0.43, 0.37, 0.76, 0.48, 0.0, 0.08, 0.42, 0.12, 0.01, 0.19, 0.76, 0.34, 0.0, 0.45, 0.12, 0.59, 0.06, 0.77, 0.43, 0.03, 0.2, 0.1, 0.01, 0.02, 0.04, 0.0, 0.02, 0.01, 0.0, 0.0, 0.0, 0.0, 0.0, 0.15, 0.02, 0.01, 0.06, 0.3, 0.53, 0.04, 0.1, 0.43, 0.1, 0.74, 0.6, 0.04, 0.33, 0.05, 0.37, 0.02, 0.53, 0.58, 0.36, 0.66, 0.22, 0.05, 0.35, 0.38, 0.0, 0.0, 0.57, 0.17, 0.0, 0.32, 0.47, 0.0, 0.03, 0.82, 0.61, 0.05, 0.47, 0.1, 0.49, 0.3, 0.84, 0.06, 0.35, 0.13, 0.83, 0.53, 0.0, 0.06, 0.52, 0.09, 0.59, 0.33, 0.55, 0.23, 0.0, 0.14, 0.57, 0.01, 0.0, 0.29, 0.02, 0.0, 0.17, 0.26, 0.0, 0.05, 0.56, 0.29, 0.13, 0.35, 0.59, 0.63, 0.22, 0.99, 0.26, 0.54, 0.08, 0.55, 0.72, 0.23, 0.07, 0.67, 0.72, 0.44, 0.69, 0.17, 0.51, 0.28, 0.06, 0.37, 0.31, 0.31, 0.64, 0.66, 0.55, 0.83, 0.9, 0.76, 0.86, 0.83, 0.9, 0.77, 0.83, 0.79, 0.88, 0.89, 0.94, 0.94, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.9, 0.98, 0.9, 0.75, 0.78, 0.64, 0.61, 0.73, 0.46, 0.62, 0.67, 0.64, 0.51, 0.62, 0.57, 0.57, 0.62, 0.52, 0.33, 0.51, 0.64, 0.58, 0.45, 0.47, 0.59, 0.28, 0.67, 0.63, 0.55, 0.5, 0.56, 0.45, 0.36, 0.47, 0.38, 0.6, 0.45, 0.62, 0.63, 0.62, 0.62, 0.65, 0.32, 0.47, 0.5, 0.4, 0.63, 0.41, 0.17, 0.38, 0.54, 0.1, 0.53, 0.83, 0.6, 0.16, 0.97, 0.9, 0.6, 0.7, 0.6, 0.6, 0.17, 0.55, 0.59, 0.34, 0.15, 0.53, 0.72, 0.31, 0.59, 0.5, 0.57, 0.85, 0.92, 0.75, 0.78, 0.88, 0.79, 0.9, 0.82, 0.88, 0.92, 0.88, 0.83, 0.8, 0.9, 0.78, 0.82, 0.79, 0.87, 0.78, 0.89, 0.91, 0.99, 0.97, 0.99, 0.98, 0.98, 1.0]
null
null
null
null
POLA1, MCM10, DNA2, CDC45, GINS2
null
null
null
null
Trimer
null
74.106794
0.493543
73.856544
0.553394
2,277
O75928
P42224
12764129, E3Net
UbiNet, UbiBrowser, 31181401
PIAS2
MADFEELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIRELYRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGSVLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFIFALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFPLPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLTSAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQEDGSWCPMRPKKEAMKVSSQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSDEEEDPPAKRKCIFMSETQSSPTKGVLMYQPSSVRVPSVTSVDPAAIPPSLTDYSVPFHHTPISSMSSDLPGLDFLSLIPVDPQYCPPMFLDSLTSPLTASSTSVTTTSSHESSTHVSSSSSRSETGVITSSGSNIPDIISLD
Homo sapiens
Nucleus speckle, Nucleus, PML body, Nucleus
Tissue enriched (testis)
{'Ciliated cells': '18.1', 'Basal respiratory cells': '22.3', 'Club cells': '22.0', 'Ionocytes': '30.2', 'Mucus glandular cells': '21.2', 'Serous glandular cells': '24.4', 'Gastric mucus-secreting cells': '17.7', 'Proximal enterocytes': '10.4', 'Paneth cells': '12.6', 'Distal enterocytes': '23.4', 'Intestinal goblet cells': '17.9', 'Exocrine glandular cells': '-0.426', 'Basal prostatic cells': '28.6', 'Prostatic glandular cells': '59.4', 'Breast glandular cells': '0.432', 'Breast myoepithelial cells': '0.441', 'Glandular and luminal cells': '13.9', 'Secretory cells': '16.5', 'Basal keratinocytes': '21.9', 'Suprabasal keratinocytes': '16.5', 'Basal squamous epithelial cells': '26.6', 'Squamous epithelial cells': '22.5', 'Alveolar cells type 1': '-0.019', 'Alveolar cells type 2': '-0.375', 'Salivary duct cells': '23.1', 'Ductal cells': '0.490', 'Hepatocytes': '0.278', 'Cholangiocytes': '9.5', 'Proximal tubular cells': '0.132', 'Distal tubular cells': '15.4', 'Collecting duct cells': '21.4', 'Mesothelial cells': '0.361', 'Sertoli cells': '-0.510', 'Granulosa cells': '18.1', 'Enteroendocrine cells': '17.5', 'Pancreatic endocrine cells': '11.9', 'Leydig cells': '-0.523', 'Excitatory neurons': '133.2', 'Inhibitory neurons': '129.2', 'Cone photoreceptor cells': '56.1', 'Rod photoreceptor cells': '40.0', 'Bipolar cells': '41.0', 'Horizontal cells': '73.6', 'Astrocytes': '57.3', 'Oligodendrocyte precursor cells': '125.5', 'Oligodendrocytes': '87.5', 'Microglial cells': '69.8', 'Muller glia cells': '21.0', 'Schwann cells': '0.086', 'Spermatogonia': '-0.255', 'Spermatocytes': '0.158', 'Early spermatids': '0.920', 'Late spermatids': '0.651', 'Oocytes': '45.6', 'Cytotrophoblasts': '2.4', 'Syncytiotrophoblasts': '1.2', 'Extravillous trophoblasts': '2.3', 'Endothelial cells': '24.4', 'Lymphatic endothelial cells': '15.0', 'Cardiomyocytes': '0.631', 'Skeletal myocytes': '-0.207', 'Smooth muscle cells': '16.9', 'Adipocytes': '25.4', 'Melanocytes': '0.019', 'Fibroblasts': '20.0', 'Peritubular cells': '-0.316', 'Endometrial stromal cells': '22.3', 'Ovarian stromal cells': '17.2', 'Undifferentiated cells': '23.3', 'T-cells': '20.3', 'B-cells': '22.8', 'Plasma cells': '19.2', 'Nk-cells': '39.7', 'Granulocytes': '12.5', 'Monocytes': '19.9', 'Macrophages': '28.8', 'Hofbauer cells': '27.1', 'Kupffer cells': '38.8', 'Dendritic cells': '35.7', 'Langerhans cells': '0.056', 'Erythroid cells': '0.124', 'Adipocytes (Subcutaneous)': '-0.032', 'Adipocytes (Visceral)': '-0.319', 'Breast glandular cells (progenitors)': '0.277', 'Adipocytes (Breast)': '-0.408', 'Colon enterocytes': '-0.130', 'Colon enteroendocrine cells': '0.287', 'Enteric glia cells': '0.367', 'Mitotic cells (Colon)': '-0.011', 'Mitotic cells (Heart)': '0.504', 'Podocytes': '0.042', 'Ascending Loop of Henle cells': '0.427', 'Intercalated cells': '0.074', 'Cholangiocyte': '0.290', 'NK-cells (Liver)': '-0.174', 'Respiratory ciliated cells': '0.113', 'Mitotic cells (Lung)': '0.033', 'NK-cells (Lung)': '0.297', 'B-cells (Lung)': '0.184', 'Alpha cells': '0.411', 'Beta cells': '0.301', 'Prostate glandular cells': '0.152', 'Prostate basal glandular cells': '0.329', 'Urothelial cells': '0.210', 'Keratinocyte (other)': '0.003', 'Keratinocyte (granular)': '-0.375', 'Hair cortex cells': '-0.065', 'Inner root sheath cells': '-0.022', 'Outer root sheath cells': '0.213', 'Sebaceous gland cells': '0.086', 'Eccrine sweat gland cells': '0.127', 'Adipocytes (Skin)': '-0.017', 'Mitotic cells (Skin)': '0.165', 'Parietal cells': '-0.524', 'Chief cells': '-0.483', 'Gastric mucous cells': '-0.393', 'Gastric enteroendocrine cells': '-0.320', 'Mitotic cells (Stomach)': '-0.043', 'Parafollicular cells': '0.122', 'Thyroid glandular cells': '0.188', 'Mitotic cells (Thyroid)': '-0.047', 'Adrenal cortex cells': '0.300', 'Adrenal medulla cells': '-0.075', 'Mitotic cells (Adrenal gland)': '0.117', 'Minor salivary glandular cells': '0.423', 'Minor salivary gland ductal cells': '0.375', 'Minor salivary gland basal cells': '-0.044', 'Mitotic cells (Minor salivary gland)': '-0.087', 'Adipocytes (Minor salivary gland)': '0.095', 'Somatotropes': '0.019', 'Lactotropes': '-0.124', 'Gonadotropes': '0.008', 'Corticotropes': '-0.215', 'Thyrotropes': '0.038', 'Undifferentiated cells (Pituitary gland)': '0.160', 'Mitotic cells (Spleen)': '-0.199', 'Platelets': '-0.035', 'Erythrocytes': '-0.053', 'Hematopoietic stem cells': '-0.104', 'B-cells (Spleen)': '0.273', 'NK-cells (Spleen)': '0.302', 'Amygdala excitatory': '210.8', 'Cerebellar inhibitory': '185.7', 'Cge interneuron': '186.0', 'Deep-layer corticothalamic and 6b': '200.5', 'Deep-layer intratelencephalic': '199.5', 'Deep-layer near-projecting': '201.2', 'Eccentric medium spiny neuron': '207.0', 'Hippocampal ca1-3': '202.5', 'Hippocampal ca4': '165.2', 'Hippocampal dentate gyrus': '191.2', 'Lamp5-lhx6 and chandelier': '186.5', 'Lower rhombic lip': '164.9', 'Mammillary body': '228.9', 'Medium spiny neuron': '216.1', 'Mge interneuron': '198.3', 'Midbrain-derived inhibitory': '156.7', 'Miscellaneous': '194.1', 'Splatter': '169.8', 'Thalamic excitatory': '175.9', 'Upper rhombic lip': '196.0', 'Upper-layer intratelencephalic': '200.0', 'Astrocyte': '126.0', 'Bergmann glia': '103.3', 'Central nervous system macrophage': '177.6', 'Choroid plexus epithelial cell': '174.1', 'Committed oligodendrocyte precursor': '119.3', 'Ependymal cell': '106.1', 'Oligodendrocyte': '142.2', 'Oligodendrocyte precursor cell': '184.1', 'Endothelial cell': '212.9', 'Pericyte': '70.4', 'Vascular associated smooth muscle cell': '76.1', 'Fibroblast': '123.8', 'Leukocyte': '95.9', 'Basophil': '1.9', 'Eosinophil': '1.2', 'Neutrophil': '9.7', 'Classical monocyte': '5.3', 'Non-classical monocyte': '4.6', 'Intermediate monocyte': '11.9', 'T-reg': '14.2', 'GdT-cell': '2.0', 'MAIT T-cell': '15.2', 'Memory CD4 T-cell': '1.8', 'Naive CD4 T-cell': '13.4', 'Memory CD8 T-cell': '2.3', 'Naive CD8 T-cell': '12.4', 'Memory B-cell': '1.6', 'Naive B-cell': '14.2', 'Plasmacytoid DC': '11.6', 'Myeloid DC': '16.8', 'NK-cell': '11.3', 'Total PBMC': '11.6', 'Vd2 gdTCR': '18.0', 'Memory CD4 T-cell Th1\\/Th17': '9.7', 'Memory CD4 T-cell Th17': '7.5', 'Memory CD4 T-cell Th2': '10.2', 'Non-Vd2 gdTCR': '12.2', 'Memory CD4 T-cell Th1': '8.8', 'Memory CD4 T-cell TFH': '8.6', 'Terminal effector memory CD4 T-cell': '17.9', 'Central memory CD8 T-cell': '19.5', 'Effector memory CD8 T-cell': '13.6', 'Terminal effector memory CD8 T-cell': '13.9', 'Non-switched memory B-cell': '13.9', 'Plasmablast': '13.8', 'Switched memory B-cell': '12.5', 'Exhausted memory B-cell': '12.1', 'Progenitor cell': '19.0', 'Memory T-reg': '5.7', 'Naive CD4 T-cell activated': '10.1', 'Naive CD8 T-cell activated': '9.1', 'Naive T-reg': '13.5'}
2ASQ, 4FO9
{'Adipose Tissue': 4.388922342192691, 'Adrenal Gland': 4.221116279069768, 'Bladder': 4.650761904761905, 'Blood': 2.4698632292787943, 'Blood Vessel': 4.738003745318352, 'Brain': 5.345703179409538, 'Breast': 4.464736383442266, 'Cervix Uteri': 6.278, 'Colon': 4.3603530166880615, 'Esophagus': 3.8689568166089967, 'Fallopian Tube': 5.788111111111111, 'Heart': 2.244122764227642, 'Kidney': 2.928967415730337, 'Liver': 1.8024977876106196, 'Lung': 5.046228373702422, 'Muscle': 4.860178082191781, 'Nerve': 6.048297253634895, 'Ovary': 6.044716666666667, 'Pancreas': 1.4900079268292683, 'Pituitary': 6.315487632508834, 'Prostate': 6.391844897959183, 'Salivary Gland': 4.655388888888889, 'Skin': 4.4644571586511885, 'Small Intestine': 4.059080213903743, 'Spleen': 5.5481244813278, 'Stomach': 3.335621169916435, 'Testis': 27.603548476454293, 'Thyroid': 7.279647779479325, 'Uterus': 6.194323943661972, 'Vagina': 5.0930256410256405}
STAT1
MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKTLQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLNVTELTQNALINDELVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPITKNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEVHPSRLQTTDNLLPMSPEEFDEVSRIVGSVEFDSMMNTV
Homo sapiens
Cytoplasm, Nucleus
Low tissue specificity
{'Ciliated cells': '33.0', 'Basal respiratory cells': '29.9', 'Club cells': '30.5', 'Ionocytes': '23.2', 'Mucus glandular cells': '27.9', 'Serous glandular cells': '21.2', 'Gastric mucus-secreting cells': '52.5', 'Proximal enterocytes': '23.5', 'Paneth cells': '21.5', 'Distal enterocytes': '40.3', 'Intestinal goblet cells': '32.6', 'Exocrine glandular cells': '-0.610', 'Basal prostatic cells': '23.0', 'Prostatic glandular cells': '33.4', 'Breast glandular cells': '0.141', 'Breast myoepithelial cells': '0.192', 'Glandular and luminal cells': '39.8', 'Secretory cells': '23.0', 'Basal keratinocytes': '22.9', 'Suprabasal keratinocytes': '29.6', 'Basal squamous epithelial cells': '23.3', 'Squamous epithelial cells': '29.0', 'Alveolar cells type 1': '0.002', 'Alveolar cells type 2': '-0.161', 'Salivary duct cells': '29.6', 'Ductal cells': '0.627', 'Hepatocytes': '0.456', 'Cholangiocytes': '43.9', 'Proximal tubular cells': '0.272', 'Distal tubular cells': '6.1', 'Collecting duct cells': '48.6', 'Mesothelial cells': '0.200', 'Sertoli cells': '0.388', 'Granulosa cells': '22.6', 'Enteroendocrine cells': '14.4', 'Pancreatic endocrine cells': '20.4', 'Leydig cells': '0.579', 'Excitatory neurons': '8.7', 'Inhibitory neurons': '11.7', 'Cone photoreceptor cells': '8.5', 'Rod photoreceptor cells': '20.5', 'Bipolar cells': '12.7', 'Horizontal cells': '8.2', 'Astrocytes': '13.3', 'Oligodendrocyte precursor cells': '23.6', 'Oligodendrocytes': '11.1', 'Microglial cells': '30.4', 'Muller glia cells': '13.7', 'Schwann cells': '0.142', 'Spermatogonia': '0.656', 'Spermatocytes': '0.350', 'Early spermatids': '-0.206', 'Late spermatids': '-0.552', 'Oocytes': '38.2', 'Cytotrophoblasts': '13.7', 'Syncytiotrophoblasts': '7.9', 'Extravillous trophoblasts': '60.8', 'Endothelial cells': '41.2', 'Lymphatic endothelial cells': '32.6', 'Cardiomyocytes': '0.581', 'Skeletal myocytes': '-0.093', 'Smooth muscle cells': '25.3', 'Adipocytes': '45.1', 'Melanocytes': '0.312', 'Fibroblasts': '35.8', 'Peritubular cells': '0.465', 'Endometrial stromal cells': '45.2', 'Ovarian stromal cells': '22.8', 'Undifferentiated cells': '26.0', 'T-cells': '71.6', 'B-cells': '41.2', 'Plasma cells': '63.4', 'Nk-cells': '48.6', 'Granulocytes': '24.5', 'Monocytes': '66.6', 'Macrophages': '85.4', 'Hofbauer cells': '110.3', 'Kupffer cells': '62.8', 'Dendritic cells': '55.2', 'Langerhans cells': '0.428', 'Erythroid cells': '-0.150', 'Adipocytes (Subcutaneous)': '-0.095', 'Adipocytes (Visceral)': '-0.030', 'Breast glandular cells (progenitors)': '-0.104', 'Adipocytes (Breast)': '-0.179', 'Colon enterocytes': '-0.106', 'Colon enteroendocrine cells': '0.315', 'Enteric glia cells': '-0.017', 'Mitotic cells (Colon)': '0.092', 'Mitotic cells (Heart)': '0.527', 'Podocytes': '-0.027', 'Ascending Loop of Henle cells': '0.270', 'Intercalated cells': '-0.046', 'Cholangiocyte': '0.352', 'NK-cells (Liver)': '-0.226', 'Respiratory ciliated cells': '0.004', 'Mitotic cells (Lung)': '0.154', 'NK-cells (Lung)': '0.392', 'B-cells (Lung)': '0.196', 'Alpha cells': '0.284', 'Beta cells': '0.117', 'Prostate glandular cells': '-0.052', 'Prostate basal glandular cells': '0.085', 'Urothelial cells': '0.152', 'Keratinocyte (other)': '0.437', 'Keratinocyte (granular)': '-0.132', 'Hair cortex cells': '-0.088', 'Inner root sheath cells': '0.005', 'Outer root sheath cells': '0.134', 'Sebaceous gland cells': '-0.020', 'Eccrine sweat gland cells': '-0.077', 'Adipocytes (Skin)': '-0.271', 'Mitotic cells (Skin)': '0.432', 'Parietal cells': '-0.656', 'Chief cells': '-0.540', 'Gastric mucous cells': '-0.247', 'Gastric enteroendocrine cells': '-0.390', 'Mitotic cells (Stomach)': '0.213', 'Parafollicular cells': '0.059', 'Thyroid glandular cells': '0.086', 'Mitotic cells (Thyroid)': '0.340', 'Adrenal cortex cells': '0.571', 'Adrenal medulla cells': '0.055', 'Mitotic cells (Adrenal gland)': '0.314', 'Minor salivary glandular cells': '0.514', 'Minor salivary gland ductal cells': '0.031', 'Minor salivary gland basal cells': '0.313', 'Mitotic cells (Minor salivary gland)': '0.461', 'Adipocytes (Minor salivary gland)': '0.132', 'Somatotropes': '-0.197', 'Lactotropes': '-0.249', 'Gonadotropes': '0.027', 'Corticotropes': '-0.234', 'Thyrotropes': '0.038', 'Undifferentiated cells (Pituitary gland)': '0.396', 'Mitotic cells (Spleen)': '0.129', 'Platelets': '-0.072', 'Erythrocytes': '0.052', 'Hematopoietic stem cells': '-0.067', 'B-cells (Spleen)': '-0.012', 'NK-cells (Spleen)': '0.149', 'Amygdala excitatory': '119.1', 'Cerebellar inhibitory': '120.1', 'Cge interneuron': '113.2', 'Deep-layer corticothalamic and 6b': '124.1', 'Deep-layer intratelencephalic': '163.1', 'Deep-layer near-projecting': '160.0', 'Eccentric medium spiny neuron': '108.4', 'Hippocampal ca1-3': '109.6', 'Hippocampal ca4': '216.9', 'Hippocampal dentate gyrus': '275.8', 'Lamp5-lhx6 and chandelier': '132.2', 'Lower rhombic lip': '350.6', 'Mammillary body': '210.8', 'Medium spiny neuron': '110.4', 'Mge interneuron': '109.0', 'Midbrain-derived inhibitory': '140.9', 'Miscellaneous': '136.8', 'Splatter': '118.3', 'Thalamic excitatory': '149.1', 'Upper rhombic lip': '202.4', 'Upper-layer intratelencephalic': '205.9', 'Astrocyte': '52.6', 'Bergmann glia': '50.2', 'Central nervous system macrophage': '189.1', 'Choroid plexus epithelial cell': '99.1', 'Committed oligodendrocyte precursor': '95.8', 'Ependymal cell': '50.6', 'Oligodendrocyte': '91.8', 'Oligodendrocyte precursor cell': '127.4', 'Endothelial cell': '268.5', 'Pericyte': '130.9', 'Vascular associated smooth muscle cell': '122.1', 'Fibroblast': '113.8', 'Leukocyte': '198.1', 'Basophil': '163.3', 'Eosinophil': '106.0', 'Neutrophil': '861.0', 'Classical monocyte': '157.3', 'Non-classical monocyte': '148.0', 'Intermediate monocyte': '467.5', 'T-reg': '349.9', 'GdT-cell': '51.9', 'MAIT T-cell': '317.8', 'Memory CD4 T-cell': '130.9', 'Naive CD4 T-cell': '202.7', 'Memory CD8 T-cell': '78.4', 'Naive CD8 T-cell': '176.8', 'Memory B-cell': '39.2', 'Naive B-cell': '52.8', 'Plasmacytoid DC': '426.2', 'Myeloid DC': '246.3', 'NK-cell': '109.4', 'Total PBMC': '280.0', 'Vd2 gdTCR': '236.8', 'Memory CD4 T-cell TFH': '160.6', 'Memory CD4 T-cell Th2': '191.1', 'Memory CD4 T-cell Th17': '168.9', 'Memory CD4 T-cell Th1\\/Th17': '198.4', 'Non-Vd2 gdTCR': '195.9', 'Memory CD4 T-cell Th1': '189.6', 'Terminal effector memory CD4 T-cell': '187.9', 'Central memory CD8 T-cell': '359.0', 'Effector memory CD8 T-cell': '359.3', 'Terminal effector memory CD8 T-cell': '203.8', 'Switched memory B-cell': '152.1', 'Plasmablast': '226.0', 'Non-switched memory B-cell': '179.2', 'Exhausted memory B-cell': '137.5', 'Progenitor cell': '152.1', 'Memory T-reg': '227.8', 'Naive CD4 T-cell activated': '627.6', 'Naive CD8 T-cell activated': '808.5', 'Naive T-reg': '170.1'}
1BF5, 1YVL, 2KA6, 3WWT, 7NUF, 8D3F
{'Adipose Tissue': 50.47876245847176, 'Adrenal Gland': 41.741511627906974, 'Bladder': 43.53142857142857, 'Blood': 131.40868891280948, 'Blood Vessel': 52.140711610486896, 'Brain': 22.11497615442846, 'Breast': 43.084945533769066, 'Cervix Uteri': 49.96526315789474, 'Colon': 40.31694480102696, 'Esophagus': 36.73342283737024, 'Fallopian Tube': 37.52222222222222, 'Heart': 17.118678745644598, 'Kidney': 43.45974157303371, 'Liver': 22.487460176991153, 'Lung': 73.2406401384083, 'Muscle': 19.9420099626401, 'Nerve': 50.33907915993538, 'Ovary': 39.602333333333334, 'Pancreas': 13.675429878048782, 'Pituitary': 41.25586572438163, 'Prostate': 44.60583673469388, 'Salivary Gland': 34.556234567901235, 'Skin': 92.85099502487564, 'Small Intestine': 46.47556149732621, 'Spleen': 74.0811203319502, 'Stomach': 31.32184679665738, 'Testis': 28.428947368421053, 'Thyroid': 47.69983154670751, 'Uterus': 42.921619718309856, 'Vagina': 43.66641025641026}
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96.96, 97.14, 95.26, 92.82, 91.65, 92.09, 92.98, 93.73, 93.52, 93.51, 93.64, 93.79, 91.49, 86.98, 91.24, 90.91, 91.56, 91.6, 96.08, 97.12, 96.37, 97.75, 97.33, 97.53, 94.86, 92.25, 89.56, 91.46, 91.2, 89.34, 91.91, 96.49, 97.7, 96.75, 96.13, 95.54, 95.05, 93.54, 89.19, 82.3, 71.34, 67.89, 62.81, 66.85, 71.07, 81.16, 85.59, 88.6, 91.58, 92.09, 92.41, 92.8, 92.59, 94.78, 95.76, 95.76, 94.28, 93.57, 93.0, 94.23, 92.63, 91.44, 91.9, 93.82, 96.27, 95.75, 93.78, 94.52, 95.38, 94.06, 91.42, 91.51, 88.23, 84.44, 75.31, 69.65, 66.63, 66.19, 71.53, 75.75, 82.0, 85.26, 88.54, 91.62, 94.1, 94.21, 96.33, 96.32, 92.98, 88.92, 91.5, 93.2, 95.64, 95.39, 94.14, 92.12, 92.22, 95.51, 92.88, 90.17, 93.28, 93.38, 87.94, 77.48, 62.08, 52.99, 39.24, 39.48, 40.12, 38.98, 44.24, 41.38, 37.88, 45.32, 37.87, 48.73, 43.16, 40.67, 42.43, 43.92, 48.01, 49.26, 46.96, 53.25, 49.83, 62.21, 69.39, 67.44, 70.17, 66.33, 66.06, 57.14, 53.79, 45.0, 31.38, 38.83, 45.16, 35.61, 35.21, 33.39, 40.3, 42.33, 42.76, 40.95, 45.32, 55.27, 54.59, 69.61, 67.84, 72.52, 68.47, 70.07, 70.62, 71.62, 62.97, 62.91, 68.24, 66.07, 55.67, 44.4, 48.26, 50.12, 48.15, 46.23, 46.55, 46.08, 43.03, 45.27, 41.19, 39.81, 39.23]
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null
null
null
null
SUMO1 , UBE2I, AXIN1, JUN, MDM2, PARK7, TP53 , TP73 isoform alpha, STAT4, GTF2I, GTF2IRD1, IKFZ1, DAB2 , MSX2, ESR1, ESR2, NR3C1, PGR, AR, NCOA2, sumoylated ELK1, PLAG1, KLF8, PRDM1
null
null
null
UBE2I
null
null
70.4343
0.60934
87.709773
0.36164
724
O76050
O76083
31068605
UbiNet, UbiBrowser
NEURL1
MGNNFSSIPSLPRGNPSRAPRGHPQNLKDSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDPLLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
Homo sapiens
Cytoplasm, perinuclear region, Cell membrane, Perikaryon, Cell projection, dendrite, Postsynaptic density
Tissue enhanced (brain, skeletal muscle, tongue)
{'Ciliated cells': '0.8', 'Basal respiratory cells': '0.2', 'Club cells': '0.7', 'Ionocytes': '4.8', 'Mucus glandular cells': '0.4', 'Serous glandular cells': '0.1', 'Gastric mucus-secreting cells': '10.6', 'Proximal enterocytes': '5.8', 'Paneth cells': '210.3', 'Distal enterocytes': '7.3', 'Intestinal goblet cells': '127.0', 'Exocrine glandular cells': '-0.415', 'Basal prostatic cells': '1.2', 'Prostatic glandular cells': '0.7', 'Breast glandular cells': '0.586', 'Breast myoepithelial cells': '0.427', 'Glandular and luminal cells': '0.1', 'Secretory cells': '6.0', 'Basal keratinocytes': '0.6', 'Suprabasal keratinocytes': '1.1', 'Basal squamous epithelial cells': '0.0', 'Squamous epithelial cells': '0.0', 'Alveolar cells type 1': '0.101', 'Alveolar cells type 2': '-0.242', 'Salivary duct cells': '5.6', 'Ductal cells': '0.372', 'Hepatocytes': '0.256', 'Cholangiocytes': '0.0', 'Proximal tubular cells': '0.157', 'Distal tubular cells': '0.0', 'Collecting duct cells': '0.0', 'Mesothelial cells': '0.080', 'Sertoli cells': '-0.564', 'Granulosa cells': '6.6', 'Enteroendocrine cells': '44.9', 'Pancreatic endocrine cells': '5.1', 'Leydig cells': '-0.585', 'Excitatory neurons': '46.3', 'Inhibitory neurons': '31.5', 'Cone photoreceptor cells': '98.6', 'Rod photoreceptor cells': '84.4', 'Bipolar cells': '53.3', 'Horizontal cells': '20.1', 'Astrocytes': '1.2', 'Oligodendrocyte precursor cells': '0.9', 'Oligodendrocytes': '3.9', 'Microglial cells': '0.0', 'Muller glia cells': '7.9', 'Schwann cells': '0.580', 'Spermatogonia': '-0.217', 'Spermatocytes': '0.109', 'Early spermatids': '0.580', 'Late spermatids': '0.774', 'Oocytes': '56.6', 'Cytotrophoblasts': '4.4', 'Syncytiotrophoblasts': '132.2', 'Extravillous trophoblasts': '14.2', 'Endothelial cells': '1.5', 'Lymphatic endothelial cells': '0.2', 'Cardiomyocytes': '0.251', 'Skeletal myocytes': '0.478', 'Smooth muscle cells': '0.7', 'Adipocytes': '0.4', 'Melanocytes': '0.084', 'Fibroblasts': '0.9', 'Peritubular cells': '-0.482', 'Endometrial stromal cells': '0.6', 'Ovarian stromal cells': '4.3', 'Undifferentiated cells': '12.2', 'T-cells': '1.9', 'B-cells': '1.1', 'Plasma cells': '0.9', 'Nk-cells': '1.1', 'Granulocytes': '0.9', 'Monocytes': '53.3', 'Macrophages': '4.0', 'Hofbauer cells': '6.1', 'Kupffer cells': '4.6', 'Dendritic cells': '4.4', 'Langerhans cells': '0.149', 'Erythroid cells': '0.072', 'Adipocytes (Subcutaneous)': '-0.214', 'Adipocytes (Visceral)': '-0.076', 'Breast glandular cells (progenitors)': '0.356', 'Adipocytes (Breast)': '-0.448', 'Colon enterocytes': '0.608', 'Colon enteroendocrine cells': '0.340', 'Enteric glia cells': '0.091', 'Mitotic cells (Colon)': '0.322', 'Mitotic cells (Heart)': '0.346', 'Podocytes': '0.303', 'Ascending Loop of Henle cells': '-0.077', 'Intercalated cells': '0.422', 'Cholangiocyte': '0.090', 'NK-cells (Liver)': '0.113', 'Respiratory ciliated cells': '0.115', 'Mitotic cells (Lung)': '-0.030', 'NK-cells (Lung)': '0.516', 'B-cells (Lung)': '0.285', 'Alpha cells': '0.555', 'Beta cells': '0.479', 'Prostate glandular cells': '-0.290', 'Prostate basal glandular cells': '0.080', 'Urothelial cells': '0.115', 'Keratinocyte (other)': '0.077', 'Keratinocyte (granular)': '0.151', 'Hair cortex cells': '-0.064', 'Inner root sheath cells': '-0.050', 'Outer root sheath cells': '-0.023', 'Sebaceous gland cells': '0.174', 'Eccrine sweat gland cells': '-0.175', 'Adipocytes (Skin)': '-0.094', 'Mitotic cells (Skin)': '-0.089', 'Parietal cells': '0.448', 'Chief cells': '0.526', 'Gastric mucous cells': '0.654', 'Gastric enteroendocrine cells': '0.781', 'Mitotic cells (Stomach)': '0.276', 'Parafollicular cells': '0.418', 'Thyroid glandular cells': '-0.073', 'Mitotic cells (Thyroid)': '0.049', 'Adrenal cortex cells': '0.062', 'Adrenal medulla cells': '0.764', 'Mitotic cells (Adrenal gland)': '0.096', 'Minor salivary glandular cells': '0.068', 'Minor salivary gland ductal cells': '0.430', 'Minor salivary gland basal cells': '0.128', 'Mitotic cells (Minor salivary gland)': '0.012', 'Adipocytes (Minor salivary gland)': '0.330', 'Somatotropes': '0.450', 'Lactotropes': '0.486', 'Gonadotropes': '0.176', 'Corticotropes': '0.063', 'Thyrotropes': '0.194', 'Undifferentiated cells (Pituitary gland)': '-0.284', 'Mitotic cells (Spleen)': '-0.292', 'Platelets': '0.134', 'Erythrocytes': '-0.126', 'Hematopoietic stem cells': '-0.035', 'B-cells (Spleen)': '0.124', 'NK-cells (Spleen)': '0.118', 'Amygdala excitatory': '104.0', 'Cerebellar inhibitory': '10.9', 'Cge interneuron': '63.6', 'Deep-layer corticothalamic and 6b': '87.1', 'Deep-layer intratelencephalic': '79.5', 'Deep-layer near-projecting': '71.3', 'Eccentric medium spiny neuron': '106.3', 'Hippocampal ca1-3': '78.3', 'Hippocampal ca4': '45.0', 'Hippocampal dentate gyrus': '76.5', 'Lamp5-lhx6 and chandelier': '52.8', 'Lower rhombic lip': '41.2', 'Mammillary body': '43.4', 'Medium spiny neuron': '98.3', 'Mge interneuron': '59.0', 'Midbrain-derived inhibitory': '71.3', 'Miscellaneous': '108.0', 'Splatter': '52.7', 'Thalamic excitatory': '36.3', 'Upper rhombic lip': '84.7', 'Upper-layer intratelencephalic': '105.8', 'Astrocyte': '2.3', 'Bergmann glia': '0.5', 'Central nervous system macrophage': '2.1', 'Choroid plexus epithelial cell': '1.3', 'Committed oligodendrocyte precursor': '9.8', 'Ependymal cell': '4.4', 'Oligodendrocyte': '11.7', 'Oligodendrocyte precursor cell': '8.5', 'Endothelial cell': '1.9', 'Pericyte': '7.8', 'Vascular associated smooth muscle cell': '8.3', 'Fibroblast': '8.9', 'Leukocyte': '18.9', 'Basophil': '3.1', 'Eosinophil': '0.5', 'Neutrophil': '7.7', 'Classical monocyte': '3.9', 'Non-classical monocyte': '102.4', 'Intermediate monocyte': '81.1', 'T-reg': '3.5', 'GdT-cell': '0.7', 'MAIT T-cell': '1.6', 'Memory CD4 T-cell': '1.0', 'Naive CD4 T-cell': '0.9', 'Memory CD8 T-cell': '1.0', 'Naive CD8 T-cell': '1.1', 'Memory B-cell': '1.0', 'Naive B-cell': '0.2', 'Plasmacytoid DC': '5.2', 'Myeloid DC': '4.1', 'NK-cell': '0.5', 'Total PBMC': '11.2', 'Vd2 gdTCR': '1.9', 'Memory CD4 T-cell Th1\\/Th17': '0.9', 'Memory CD4 T-cell Th17': '1.2', 'Memory CD4 T-cell Th2': '1.2', 'Non-Vd2 gdTCR': '2.0', 'Memory CD4 T-cell Th1': '1.1', 'Memory CD4 T-cell TFH': '2.1', 'Terminal effector memory CD4 T-cell': '1.3', 'Central memory CD8 T-cell': '2.2', 'Effector memory CD8 T-cell': '2.0', 'Terminal effector memory CD8 T-cell': '1.3', 'Non-switched memory B-cell': '4.1', 'Plasmablast': '1.5', 'Switched memory B-cell': '2.7', 'Exhausted memory B-cell': '3.6', 'Progenitor cell': '5.2', 'Memory T-reg': '1.2', 'Naive CD4 T-cell activated': '4.3', 'Naive CD8 T-cell activated': '3.3', 'Naive T-reg': '1.2'}
null
{'Adipose Tissue': 0.4564397840531561, 'Adrenal Gland': 1.204162441860465, 'Bladder': 18.47709523809524, 'Blood': 1.7706772228202368, 'Blood Vessel': 0.4057119400749064, 'Brain': 43.1193561317184, 'Breast': 0.717380522875817, 'Cervix Uteri': 19.224526315789475, 'Colon': 7.70521245186136, 'Esophagus': 0.5956358546712802, 'Fallopian Tube': 4.1434444444444445, 'Heart': 0.186807862950058, 'Kidney': 1.7366550561797751, 'Liver': 0.5106267876106194, 'Lung': 1.0154645328719722, 'Muscle': 39.288688667496885, 'Nerve': 1.5445885298869142, 'Ovary': 3.848353888888889, 'Pancreas': 9.153310975609756, 'Pituitary': 24.111098586572435, 'Prostate': 2.094164081632653, 'Salivary Gland': 2.5744364197530865, 'Skin': 0.8497301713653953, 'Small Intestine': 11.16527219251337, 'Spleen': 1.934723651452282, 'Stomach': 2.8787005571030644, 'Testis': 23.71963988919668, 'Thyroid': 0.4649907044410413, 'Uterus': 31.573427464788733, 'Vagina': 3.7810717948717953}
PDE9A
MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Homo sapiens
Cell projection, ruffle membrane, Cytoplasm, perinuclear region, Golgi apparatus, Endoplasmic reticulum, Cell membrane, sarcolemma, Cell projection, ruffle membrane, Cytoplasm, perinuclear region, Cytoplasm, Endoplasmic reticulum, Cytoplasm, Endoplasmic reticulum
Tissue enhanced (intestine)
{'Ciliated cells': '6.9', 'Basal respiratory cells': '4.5', 'Club cells': '5.4', 'Ionocytes': '7.0', 'Mucus glandular cells': '11.2', 'Serous glandular cells': '3.9', 'Gastric mucus-secreting cells': '1.8', 'Proximal enterocytes': '213.7', 'Paneth cells': '72.0', 'Distal enterocytes': '75.7', 'Intestinal goblet cells': '25.5', 'Exocrine glandular cells': '-0.648', 'Basal prostatic cells': '5.5', 'Prostatic glandular cells': '108.8', 'Breast glandular cells': '0.500', 'Breast myoepithelial cells': '0.472', 'Glandular and luminal cells': '24.5', 'Secretory cells': '15.4', 'Basal keratinocytes': '0.3', 'Suprabasal keratinocytes': '0.5', 'Basal squamous epithelial cells': '3.1', 'Squamous epithelial cells': '0.3', 'Alveolar cells type 1': '0.178', 'Alveolar cells type 2': '-0.250', 'Salivary duct cells': '12.6', 'Ductal cells': '0.576', 'Hepatocytes': '-0.057', 'Cholangiocytes': '5.7', 'Proximal tubular cells': '-0.030', 'Distal tubular cells': '15.4', 'Collecting duct cells': '9.7', 'Mesothelial cells': '0.254', 'Sertoli cells': '0.323', 'Granulosa cells': '8.8', 'Enteroendocrine cells': '30.0', 'Pancreatic endocrine cells': '8.5', 'Leydig cells': '0.469', 'Excitatory neurons': '5.3', 'Inhibitory neurons': '10.4', 'Cone photoreceptor cells': '0.0', 'Rod photoreceptor cells': '1.4', 'Bipolar cells': '25.0', 'Horizontal cells': '18.3', 'Astrocytes': '41.2', 'Oligodendrocyte precursor cells': '27.4', 'Oligodendrocytes': '15.4', 'Microglial cells': '30.4', 'Muller glia cells': '11.2', 'Schwann cells': '-0.040', 'Spermatogonia': '0.365', 'Spermatocytes': '-0.046', 'Early spermatids': '-0.450', 'Late spermatids': '-0.505', 'Oocytes': '197.8', 'Cytotrophoblasts': '0.0', 'Syncytiotrophoblasts': '0.4', 'Extravillous trophoblasts': '0.1', 'Endothelial cells': '13.0', 'Lymphatic endothelial cells': '10.5', 'Cardiomyocytes': '0.267', 'Skeletal myocytes': '0.106', 'Smooth muscle cells': '5.2', 'Adipocytes': '19.0', 'Melanocytes': '-0.247', 'Fibroblasts': '5.2', 'Peritubular cells': '0.503', 'Endometrial stromal cells': '8.0', 'Ovarian stromal cells': '2.4', 'Undifferentiated cells': '23.1', 'T-cells': '3.9', 'B-cells': '0.7', 'Plasma cells': '0.4', 'Nk-cells': '0.5', 'Granulocytes': '0.3', 'Monocytes': '0.4', 'Macrophages': '1.7', 'Hofbauer cells': '7.0', 'Kupffer cells': '0.7', 'Dendritic cells': '0.4', 'Langerhans cells': '-0.283', 'Erythroid cells': '0.025', 'Adipocytes (Subcutaneous)': '-0.398', 'Adipocytes (Visceral)': '-0.360', 'Breast glandular cells (progenitors)': '0.525', 'Adipocytes (Breast)': '-0.575', 'Colon enterocytes': '-0.030', 'Colon enteroendocrine cells': '0.270', 'Enteric glia cells': '-0.052', 'Mitotic cells (Colon)': '-0.173', 'Mitotic cells (Heart)': '0.368', 'Podocytes': '-0.161', 'Ascending Loop of Henle cells': '0.634', 'Intercalated cells': '-0.060', 'Cholangiocyte': '0.281', 'NK-cells (Liver)': '-0.142', 'Respiratory ciliated cells': '0.074', 'Mitotic cells (Lung)': '-0.165', 'NK-cells (Lung)': '0.399', 'B-cells (Lung)': '0.195', 'Alpha cells': '0.466', 'Beta cells': '0.289', 'Prostate glandular cells': '0.742', 'Prostate basal glandular cells': '0.294', 'Urothelial cells': '-0.162', 'Keratinocyte (other)': '-0.588', 'Keratinocyte (granular)': '-0.362', 'Hair cortex cells': '0.373', 'Inner root sheath cells': '0.307', 'Outer root sheath cells': '0.350', 'Sebaceous gland cells': '0.066', 'Eccrine sweat gland cells': '0.915', 'Adipocytes (Skin)': '0.536', 'Mitotic cells (Skin)': '-0.031', 'Parietal cells': '-0.643', 'Chief cells': '-0.589', 'Gastric mucous cells': '-0.612', 'Gastric enteroendocrine cells': '-0.515', 'Mitotic cells (Stomach)': '-0.280', 'Parafollicular cells': '0.103', 'Thyroid glandular cells': '0.260', 'Mitotic cells (Thyroid)': '0.060', 'Adrenal cortex cells': '0.292', 'Adrenal medulla cells': '-0.055', 'Mitotic cells (Adrenal gland)': '0.145', 'Minor salivary glandular cells': '0.405', 'Minor salivary gland ductal cells': '0.596', 'Minor salivary gland basal cells': '-0.167', 'Mitotic cells (Minor salivary gland)': '-0.368', 'Adipocytes (Minor salivary gland)': '0.115', 'Somatotropes': '0.163', 'Lactotropes': '-0.121', 'Gonadotropes': '0.084', 'Corticotropes': '-0.237', 'Thyrotropes': '0.062', 'Undifferentiated cells (Pituitary gland)': '0.227', 'Mitotic cells (Spleen)': '-0.476', 'Platelets': '-0.270', 'Erythrocytes': '-0.136', 'Hematopoietic stem cells': '-0.290', 'B-cells (Spleen)': '0.174', 'NK-cells (Spleen)': '0.300', 'Amygdala excitatory': '35.8', 'Cerebellar inhibitory': '83.8', 'Cge interneuron': '21.9', 'Deep-layer corticothalamic and 6b': '29.6', 'Deep-layer intratelencephalic': '12.6', 'Deep-layer near-projecting': '140.2', 'Eccentric medium spiny neuron': '74.4', 'Hippocampal ca1-3': '18.3', 'Hippocampal ca4': '0.5', 'Hippocampal dentate gyrus': '3.2', 'Lamp5-lhx6 and chandelier': '33.3', 'Lower rhombic lip': '1.0', 'Mammillary body': '60.3', 'Medium spiny neuron': '62.2', 'Mge interneuron': '17.9', 'Midbrain-derived inhibitory': '99.7', 'Miscellaneous': '37.2', 'Splatter': '44.4', 'Thalamic excitatory': '22.2', 'Upper rhombic lip': '43.1', 'Upper-layer intratelencephalic': '3.0', 'Astrocyte': '104.8', 'Bergmann glia': '77.2', 'Central nervous system macrophage': '125.0', 'Choroid plexus epithelial cell': '5.4', 'Committed oligodendrocyte precursor': '29.6', 'Ependymal cell': '36.2', 'Oligodendrocyte': '34.2', 'Oligodendrocyte precursor cell': '65.7', 'Endothelial cell': '87.0', 'Pericyte': '18.7', 'Vascular associated smooth muscle cell': '18.4', 'Fibroblast': '21.1', 'Leukocyte': '6.7', 'Basophil': '0.0', 'Eosinophil': '0.0', 'Neutrophil': '0.1', 'Classical monocyte': '0.1', 'Non-classical monocyte': '0.1', 'Intermediate monocyte': '0.0', 'T-reg': '2.7', 'GdT-cell': '0.3', 'MAIT T-cell': '0.9', 'Memory CD4 T-cell': '0.9', 'Naive CD4 T-cell': '16.7', 'Memory CD8 T-cell': '0.2', 'Naive CD8 T-cell': '12.2', 'Memory B-cell': '0.0', 'Naive B-cell': '0.3', 'Plasmacytoid DC': '0.0', 'Myeloid DC': '0.0', 'NK-cell': '0.4', 'Total PBMC': '0.4', 'Vd2 gdTCR': '1.5', 'Memory CD4 T-cell Th1\\/Th17': '6.5', 'Memory CD4 T-cell Th17': '3.2', 'Memory CD4 T-cell Th2': '4.7', 'Non-Vd2 gdTCR': '0.2', 'Memory CD4 T-cell Th1': '10.3', 'Memory CD4 T-cell TFH': '6.3', 'Terminal effector memory CD4 T-cell': '1.4', 'Central memory CD8 T-cell': '0.0', 'Effector memory CD8 T-cell': '0.2', 'Terminal effector memory CD8 T-cell': '0.3', 'Non-switched memory B-cell': '0.0', 'Plasmablast': '0.0', 'Switched memory B-cell': '0.0', 'Exhausted memory B-cell': '0.0', 'Progenitor cell': '0.8', 'Memory T-reg': '7.0', 'Naive CD4 T-cell activated': '3.1', 'Naive CD8 T-cell activated': '4.6', 'Naive T-reg': '17.6'}
2HD1, 2YY2, 3DY8, 3DYL, 3DYN, 3DYQ, 3DYS, 3JSI, 3JSW, 3K3E, 3K3H, 3N3Z, 3QI3, 3QI4, 4E90, 4G2J, 4G2L, 4GH6, 4Y86, 4Y87, 4Y8C, 6A3N, 6LZZ, 7F0I, 8BPY
{'Adipose Tissue': 12.813147840531562, 'Adrenal Gland': 11.665903100775193, 'Bladder': 26.37842857142857, 'Blood': 0.735783638320775, 'Blood Vessel': 3.686001700374532, 'Brain': 12.593436411809234, 'Breast': 15.554030501089326, 'Cervix Uteri': 11.91157894736842, 'Colon': 94.5223863928113, 'Esophagus': 19.98899453287197, 'Fallopian Tube': 12.617555555555557, 'Heart': 2.0677188153310104, 'Kidney': 15.61426966292135, 'Liver': 2.5566991150442475, 'Lung': 7.970814878892734, 'Muscle': 1.5035789539227895, 'Nerve': 49.73311793214862, 'Ovary': 5.966866666666667, 'Pancreas': 2.299498780487805, 'Pituitary': 14.899572438162544, 'Prostate': 60.74801224489796, 'Salivary Gland': 14.862666666666666, 'Skin': 7.351489049198452, 'Small Intestine': 85.15547058823529, 'Spleen': 23.584029045643156, 'Stomach': 15.189565459610028, 'Testis': 4.1795124653739615, 'Thyroid': 11.309897396630934, 'Uterus': 10.888077464788733, 'Vagina': 10.07598076923077}
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null
null
null
null
CPEB3, DLL1
JAG1, CPEB3
mono
null
null
null
null
69.187596
0.505122
81.374654
0.423019
1,277
O76064
O14773
22101936
UbiNet, UbiBrowser
RNF8
MGEPGFFVTGDRAGGRSWCLRRVGMSAGWLLLEDGCEVTVGRGFGVTYQLVSKICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLENKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDELAGPGAEGPSNLKSKINKVSCESGQPVKSQGKGEVASTPSDNLDPKLTALEPSKTTGAPIYPGFPKVTEVHHEQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKGNSKKVVQMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGLEIAQGEKDLKQQLAQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERKAKRLF
Homo sapiens
Nucleus, Cytoplasm, Midbody, Chromosome, telomere
Low tissue specificity
{'Ciliated cells': '32.7', 'Basal respiratory cells': '25.8', 'Club cells': '21.1', 'Ionocytes': '14.7', 'Mucus glandular cells': '22.1', 'Serous glandular cells': '22.6', 'Gastric mucus-secreting cells': '17.7', 'Proximal enterocytes': '10.5', 'Paneth cells': '15.1', 'Distal enterocytes': '10.0', 'Intestinal goblet cells': '16.0', 'Exocrine glandular cells': '-0.639', 'Basal prostatic cells': '20.0', 'Prostatic glandular cells': '17.9', 'Breast glandular cells': '0.548', 'Breast myoepithelial cells': '0.568', 'Glandular and luminal cells': '55.4', 'Secretory cells': '20.7', 'Basal keratinocytes': '26.6', 'Suprabasal keratinocytes': '36.6', 'Basal squamous epithelial cells': '26.4', 'Squamous epithelial cells': '35.6', 'Alveolar cells type 1': '0.317', 'Alveolar cells type 2': '-0.116', 'Salivary duct cells': '32.2', 'Ductal cells': '0.590', 'Hepatocytes': '0.475', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.086', 'Distal tubular cells': '24.6', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.464', 'Sertoli cells': '0.410', 'Granulosa cells': '33.8', 'Enteroendocrine cells': '22.9', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '0.234', 'Excitatory neurons': '16.4', 'Inhibitory neurons': '15.3', 'Cone photoreceptor cells': '23.8', 'Rod photoreceptor cells': '28.9', 'Bipolar cells': '24.0', 'Horizontal cells': '33.4', 'Astrocytes': '12.7', 'Oligodendrocyte precursor cells': '11.8', 'Oligodendrocytes': '19.1', 'Microglial cells': '10.7', 'Muller glia cells': '24.2', 'Schwann cells': '0.051', 'Spermatogonia': '0.378', 'Spermatocytes': '0.279', 'Early spermatids': '0.119', 'Late spermatids': '-0.231', 'Oocytes': '48.5', 'Cytotrophoblasts': '26.4', 'Syncytiotrophoblasts': '4.6', 'Extravillous trophoblasts': '26.8', 'Endothelial cells': '19.7', 'Lymphatic endothelial cells': '20.6', 'Cardiomyocytes': '0.619', 'Skeletal myocytes': '-0.121', 'Smooth muscle cells': '23.0', 'Adipocytes': '20.2', 'Melanocytes': '0.232', 'Fibroblasts': '24.9', 'Peritubular cells': '0.077', 'Endometrial stromal cells': '33.0', 'Ovarian stromal cells': '30.3', 'Undifferentiated cells': '21.0', 'T-cells': '18.9', 'B-cells': '16.3', 'Plasma cells': '14.9', 'Nk-cells': '29.2', 'Granulocytes': '26.0', 'Monocytes': '7.6', 'Macrophages': '12.8', 'Hofbauer cells': '17.3', 'Kupffer cells': '11.9', 'Dendritic cells': '2.4', 'Langerhans cells': '0.124', 'Erythroid cells': '-0.012', 'Adipocytes (Subcutaneous)': '-0.436', 'Adipocytes (Visceral)': '-0.390', 'Breast glandular cells (progenitors)': '0.348', 'Adipocytes (Breast)': '-0.563', 'Colon enterocytes': '-0.240', 'Colon enteroendocrine cells': '0.233', 'Enteric glia cells': '0.133', 'Mitotic cells (Colon)': '-0.099', 'Mitotic cells (Heart)': '0.484', 'Podocytes': '-0.044', 'Ascending Loop of Henle cells': '0.513', 'Intercalated cells': '-0.001', 'Cholangiocyte': '0.376', 'NK-cells (Liver)': '-0.277', 'Respiratory ciliated cells': '0.004', 'Mitotic cells (Lung)': '0.045', 'NK-cells (Lung)': '0.113', 'B-cells (Lung)': '-0.101', 'Alpha cells': '0.425', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '0.127', 'Urothelial cells': '0.140', 'Keratinocyte (other)': '0.153', 'Keratinocyte (granular)': '-0.072', 'Hair cortex cells': '0.151', 'Inner root sheath cells': '0.238', 'Outer root sheath cells': '0.191', 'Sebaceous gland cells': '-0.083', 'Eccrine sweat gland cells': '-0.018', 'Adipocytes (Skin)': '-0.127', 'Mitotic cells (Skin)': '0.363', 'Parietal cells': '-0.661', 'Chief cells': '-0.525', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.388', 'Mitotic cells (Stomach)': '0.107', 'Parafollicular cells': '0.052', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '0.048', 'Adrenal cortex cells': '0.419', 'Adrenal medulla cells': '-0.060', 'Mitotic cells (Adrenal gland)': '0.248', 'Minor salivary glandular cells': '0.280', 'Minor salivary gland ductal cells': '-0.198', 'Minor salivary gland basal cells': '0.681', 'Mitotic cells (Minor salivary gland)': '0.719', 'Adipocytes (Minor salivary gland)': '0.238', 'Somatotropes': '-0.119', 'Lactotropes': '-0.073', 'Gonadotropes': '-0.014', 'Corticotropes': '-0.061', 'Thyrotropes': '0.233', 'Undifferentiated cells (Pituitary gland)': '0.337', 'Mitotic cells (Spleen)': '-0.155', 'Platelets': '-0.175', 'Erythrocytes': '-0.025', 'Hematopoietic stem cells': '-0.189', 'B-cells (Spleen)': '0.376', 'NK-cells (Spleen)': '0.258', 'Amygdala excitatory': '29.0', 'Cerebellar inhibitory': '39.4', 'Cge interneuron': '30.6', 'Deep-layer corticothalamic and 6b': '32.4', 'Deep-layer intratelencephalic': '28.1', 'Deep-layer near-projecting': '24.6', 'Eccentric medium spiny neuron': '32.5', 'Hippocampal ca1-3': '25.5', 'Hippocampal ca4': '28.2', 'Hippocampal dentate gyrus': '28.6', 'Lamp5-lhx6 and chandelier': '37.6', 'Lower rhombic lip': '16.6', 'Mammillary body': '30.7', 'Medium spiny neuron': '28.0', 'Mge interneuron': '25.4', 'Midbrain-derived inhibitory': '31.2', 'Miscellaneous': '25.9', 'Splatter': '26.5', 'Thalamic excitatory': '31.9', 'Upper rhombic lip': '39.0', 'Upper-layer intratelencephalic': '31.1', 'Astrocyte': '27.4', 'Bergmann glia': '29.1', 'Central nervous system macrophage': '21.1', 'Choroid plexus epithelial cell': '30.8', 'Committed oligodendrocyte precursor': '23.7', 'Ependymal cell': '22.5', 'Oligodendrocyte': '35.3', 'Oligodendrocyte precursor cell': '24.5', 'Endothelial cell': '34.2', 'Pericyte': '18.1', 'Vascular associated smooth muscle cell': '19.0', 'Fibroblast': '21.5', 'Leukocyte': '23.3', 'Basophil': '1.5', 'Eosinophil': '2.5', 'Neutrophil': '1.5', 'Classical monocyte': '3.7', 'Non-classical monocyte': '5.5', 'Intermediate monocyte': '8.2', 'T-reg': '7.3', 'GdT-cell': '9.5', 'MAIT T-cell': '7.7', 'Memory CD4 T-cell': '7.0', 'Naive CD4 T-cell': '10.8', 'Memory CD8 T-cell': '9.1', 'Naive CD8 T-cell': '8.8', 'Memory B-cell': '8.1', 'Naive B-cell': '6.3', 'Plasmacytoid DC': '3.8', 'Myeloid DC': '6.4', 'NK-cell': '13.1', 'Total PBMC': '9.1', 'Vd2 gdTCR': '11.1', 'Memory CD4 T-cell Th1\\/Th17': '10.8', 'Memory CD4 T-cell Th17': '10.8', 'Memory CD4 T-cell Th2': '9.7', 'Non-Vd2 gdTCR': '10.4', 'Memory CD4 T-cell Th1': '10.4', 'Memory CD4 T-cell TFH': '10.4', 'Terminal effector memory CD4 T-cell': '6.4', 'Central memory CD8 T-cell': '7.0', 'Effector memory CD8 T-cell': '8.2', 'Terminal effector memory CD8 T-cell': '10.0', 'Non-switched memory B-cell': '9.8', 'Plasmablast': '10.4', 'Switched memory B-cell': '6.9', 'Exhausted memory B-cell': '7.2', 'Progenitor cell': '9.2', 'Memory T-reg': '10.2', 'Naive CD4 T-cell activated': '6.2', 'Naive CD8 T-cell activated': '8.5', 'Naive T-reg': '10.5'}
2CSW, 2PIE, 4AYC, 4ORH, 4WHV
{'Adipose Tissue': 5.842281561461794, 'Adrenal Gland': 7.026077519379845, 'Bladder': 7.759809523809524, 'Blood': 3.220500215285253, 'Blood Vessel': 8.356130337078651, 'Brain': 7.779572937168812, 'Breast': 6.3104291938997825, 'Cervix Uteri': 9.987631578947369, 'Colon': 6.505412066752247, 'Esophagus': 8.088813840830449, 'Fallopian Tube': 9.497888888888887, 'Heart': 4.124628919860627, 'Kidney': 4.606573033707865, 'Liver': 2.3945101769911505, 'Lung': 7.91575259515571, 'Muscle': 4.271328767123288, 'Nerve': 8.343988691437803, 'Ovary': 10.546722222222222, 'Pancreas': 2.164347865853659, 'Pituitary': 8.595367491166078, 'Prostate': 8.065632653061224, 'Salivary Gland': 6.157123456790123, 'Skin': 8.770229961304588, 'Small Intestine': 5.831320855614974, 'Spleen': 5.645, 'Stomach': 4.767988857938719, 'Testis': 19.702216066481995, 'Thyroid': 6.970906584992344, 'Uterus': 10.236056338028169, 'Vagina': 10.048794871794872}
TPP1
MGLQACLLGLFALILSGKCSYSPEPDQRRTLPPGWVSLGRADPEEELSLTFALRQQNVERLSELVQAVSDPSSPQYGKYLTLENVADLVRPSPLTLHTVQKWLLAAGAQKCHSVITQDFLTCWLSIRQAELLLPGAEFHHYVGGPTETHVVRSPHPYQLPQALAPHVDFVGGLHRFPPTSSLRQRPEPQVTGTVGLHLGVTPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSGRHQFRPTFPASSPYVTTVGGTSFQEPFLITNEIVDYISGGGFSNVFPRPSYQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPVFGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLLNP
Homo sapiens
Lysosome, Melanosome
Low tissue specificity
{'Ciliated cells': '16.0', 'Basal respiratory cells': '29.2', 'Club cells': '27.5', 'Ionocytes': '24.7', 'Mucus glandular cells': '52.0', 'Serous glandular cells': '25.9', 'Gastric mucus-secreting cells': '16.5', 'Proximal enterocytes': '91.6', 'Paneth cells': '37.5', 'Distal enterocytes': '46.6', 'Intestinal goblet cells': '34.0', 'Exocrine glandular cells': '-0.494', 'Basal prostatic cells': '24.0', 'Prostatic glandular cells': '39.1', 'Breast glandular cells': '0.099', 'Breast myoepithelial cells': '0.201', 'Glandular and luminal cells': '24.5', 'Secretory cells': '13.6', 'Basal keratinocytes': '23.2', 'Suprabasal keratinocytes': '19.6', 'Basal squamous epithelial cells': '18.8', 'Squamous epithelial cells': '27.5', 'Alveolar cells type 1': '-0.061', 'Alveolar cells type 2': '0.248', 'Salivary duct cells': '25.0', 'Ductal cells': '0.682', 'Hepatocytes': '0.644', 'Cholangiocytes': '47.7', 'Proximal tubular cells': '0.588', 'Distal tubular cells': '3.1', 'Collecting duct cells': '13.6', 'Mesothelial cells': '0.306', 'Sertoli cells': '0.668', 'Granulosa cells': '28.3', 'Enteroendocrine cells': '22.4', 'Pancreatic endocrine cells': '32.3', 'Leydig cells': '0.661', 'Excitatory neurons': '12.1', 'Inhibitory neurons': '11.8', 'Cone photoreceptor cells': '20.4', 'Rod photoreceptor cells': '22.9', 'Bipolar cells': '25.7', 'Horizontal cells': '22.0', 'Astrocytes': '30.0', 'Oligodendrocyte precursor cells': '7.5', 'Oligodendrocytes': '20.4', 'Microglial cells': '15.2', 'Muller glia cells': '39.0', 'Schwann cells': '0.057', 'Spermatogonia': '0.552', 'Spermatocytes': '0.131', 'Early spermatids': '-0.611', 'Late spermatids': '-0.693', 'Oocytes': '8.8', 'Cytotrophoblasts': '33.8', 'Syncytiotrophoblasts': '105.4', 'Extravillous trophoblasts': '49.6', 'Endothelial cells': '42.7', 'Lymphatic endothelial cells': '37.5', 'Cardiomyocytes': '0.652', 'Skeletal myocytes': '-0.236', 'Smooth muscle cells': '26.3', 'Adipocytes': '32.3', 'Melanocytes': '0.250', 'Fibroblasts': '41.6', 'Peritubular cells': '0.494', 'Endometrial stromal cells': '29.6', 'Ovarian stromal cells': '29.1', 'Undifferentiated cells': '24.2', 'T-cells': '40.6', 'B-cells': '59.7', 'Plasma cells': '26.7', 'Nk-cells': '48.0', 'Granulocytes': '63.0', 'Monocytes': '165.9', 'Macrophages': '205.8', 'Hofbauer cells': '273.8', 'Kupffer cells': '364.8', 'Dendritic cells': '135.5', 'Langerhans cells': '0.273', 'Erythroid cells': '-0.013', 'Adipocytes (Subcutaneous)': '0.008', 'Adipocytes (Visceral)': '-0.189', 'Breast glandular cells (progenitors)': '0.103', 'Adipocytes (Breast)': '-0.081', 'Colon enterocytes': '-0.115', 'Colon enteroendocrine cells': '0.328', 'Enteric glia cells': '0.063', 'Mitotic cells (Colon)': '0.068', 'Mitotic cells (Heart)': '0.532', 'Podocytes': '0.060', 'Ascending Loop of Henle cells': '0.193', 'Intercalated cells': '-0.012', 'Cholangiocyte': '0.433', 'NK-cells (Liver)': '-0.344', 'Respiratory ciliated cells': '-0.218', 'Mitotic cells (Lung)': '0.362', 'NK-cells (Lung)': '-0.160', 'B-cells (Lung)': '-0.173', 'Alpha cells': '0.450', 'Beta cells': '0.296', 'Prostate glandular cells': '-0.214', 'Prostate basal glandular cells': '0.115', 'Urothelial cells': '0.059', 'Keratinocyte (other)': '0.174', 'Keratinocyte (granular)': '0.049', 'Hair cortex cells': '-0.080', 'Inner root sheath cells': '-0.046', 'Outer root sheath cells': '-0.021', 'Sebaceous gland cells': '-0.067', 'Eccrine sweat gland cells': '-0.025', 'Adipocytes (Skin)': '0.052', 'Mitotic cells (Skin)': '0.223', 'Parietal cells': '-0.676', 'Chief cells': '-0.597', 'Gastric mucous cells': '-0.382', 'Gastric enteroendocrine cells': '-0.433', 'Mitotic cells (Stomach)': '0.116', 'Parafollicular cells': '0.001', 'Thyroid glandular cells': '0.144', 'Mitotic cells (Thyroid)': '0.262', 'Adrenal cortex cells': '0.682', 'Adrenal medulla cells': '0.017', 'Mitotic cells (Adrenal gland)': '0.410', 'Minor salivary glandular cells': '0.641', 'Minor salivary gland ductal cells': '0.039', 'Minor salivary gland basal cells': '0.212', 'Mitotic cells (Minor salivary gland)': '0.504', 'Adipocytes (Minor salivary gland)': '0.141', 'Somatotropes': '0.087', 'Lactotropes': '-0.197', 'Gonadotropes': '-0.081', 'Corticotropes': '-0.290', 'Thyrotropes': '-0.042', 'Undifferentiated cells (Pituitary gland)': '0.262', 'Mitotic cells (Spleen)': '-0.246', 'Platelets': '0.151', 'Erythrocytes': '-0.251', 'Hematopoietic stem cells': '-0.015', 'B-cells (Spleen)': '-0.025', 'NK-cells (Spleen)': '0.129', 'Amygdala excitatory': '17.0', 'Cerebellar inhibitory': '16.0', 'Cge interneuron': '13.9', 'Deep-layer corticothalamic and 6b': '13.7', 'Deep-layer intratelencephalic': '14.2', 'Deep-layer near-projecting': '13.0', 'Eccentric medium spiny neuron': '12.8', 'Hippocampal ca1-3': '20.4', 'Hippocampal ca4': '13.4', 'Hippocampal dentate gyrus': '14.2', 'Lamp5-lhx6 and chandelier': '8.6', 'Lower rhombic lip': '20.9', 'Mammillary body': '20.5', 'Medium spiny neuron': '14.7', 'Mge interneuron': '15.7', 'Midbrain-derived inhibitory': '14.9', 'Miscellaneous': '16.5', 'Splatter': '19.5', 'Thalamic excitatory': '23.1', 'Upper rhombic lip': '11.2', 'Upper-layer intratelencephalic': '12.5', 'Astrocyte': '41.6', 'Bergmann glia': '27.2', 'Central nervous system macrophage': '43.7', 'Choroid plexus epithelial cell': '33.8', 'Committed oligodendrocyte precursor': '19.8', 'Ependymal cell': '18.2', 'Oligodendrocyte': '33.2', 'Oligodendrocyte precursor cell': '11.2', 'Endothelial cell': '26.1', 'Pericyte': '14.5', 'Vascular associated smooth muscle cell': '23.9', 'Fibroblast': '27.5', 'Leukocyte': '34.0', 'Basophil': '77.4', 'Eosinophil': '38.5', 'Neutrophil': '97.3', 'Classical monocyte': '521.2', 'Non-classical monocyte': '394.3', 'Intermediate monocyte': '347.1', 'T-reg': '71.7', 'GdT-cell': '40.2', 'MAIT T-cell': '57.8', 'Memory CD4 T-cell': '31.8', 'Naive CD4 T-cell': '113.5', 'Memory CD8 T-cell': '41.3', 'Naive CD8 T-cell': '103.5', 'Memory B-cell': '35.4', 'Naive B-cell': '163.0', 'Plasmacytoid DC': '363.5', 'Myeloid DC': '365.3', 'NK-cell': '253.2', 'Total PBMC': '236.3', 'Vd2 gdTCR': '105.7', 'Memory CD4 T-cell Th1\\/Th17': '154.0', 'Memory CD4 T-cell Th17': '141.9', 'Memory CD4 T-cell Th2': '134.8', 'Non-Vd2 gdTCR': '104.9', 'Memory CD4 T-cell Th1': '166.5', 'Memory CD4 T-cell TFH': '133.2', 'Terminal effector memory CD4 T-cell': '72.8', 'Central memory CD8 T-cell': '25.1', 'Effector memory CD8 T-cell': '133.9', 'Terminal effector memory CD8 T-cell': '124.4', 'Non-switched memory B-cell': '104.4', 'Plasmablast': '54.2', 'Switched memory B-cell': '79.1', 'Exhausted memory B-cell': '106.1', 'Progenitor cell': '120.3', 'Memory T-reg': '223.8', 'Naive CD4 T-cell activated': '97.0', 'Naive CD8 T-cell activated': '98.0', 'Naive T-reg': '156.3'}
3EDY, 3EE6
{'Adipose Tissue': 90.72033222591362, 'Adrenal Gland': 172.38313953488372, 'Bladder': 84.79523809523809, 'Blood': 93.59514639397202, 'Blood Vessel': 88.82203745318353, 'Brain': 60.25842278576835, 'Breast': 67.66226579520698, 'Cervix Uteri': 99.32631578947368, 'Colon': 80.96296534017972, 'Esophagus': 65.93249134948097, 'Fallopian Tube': 87.82222222222222, 'Heart': 35.999148664343785, 'Kidney': 57.413595505617984, 'Liver': 41.962938053097346, 'Lung': 137.36693771626298, 'Muscle': 20.59274470734745, 'Nerve': 84.47143780290791, 'Ovary': 88.29583333333333, 'Pancreas': 20.65553048780488, 'Pituitary': 103.23240282685512, 'Prostate': 65.24085714285714, 'Salivary Gland': 56.17635802469135, 'Skin': 79.34377003869541, 'Small Intestine': 99.65213903743316, 'Spleen': 192.90323651452283, 'Stomach': 56.425905292479115, 'Testis': 34.566163434903046, 'Thyroid': 85.48633996937212, 'Uterus': 124.42232394366198, 'Vagina': 73.1076923076923}
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RING finger
null
null
null
RXRA,MDC1,HERC2, PIWIL1, WRAP53
H2A,H2AX, H2B, PCNA,CHEK2, JMJD2A , KU80, POLD4
63, 48
null
UBE2N, UBE2E1, UBE2E2, UBE2E3, UBE2V2, UBE2L6
Homodimer
null
74.943402
0.531773
90.393748
0.273499
1,375
O76064
O60934
23115235
UbiNet, UbiBrowser, 31181401
RNF8
MGEPGFFVTGDRAGGRSWCLRRVGMSAGWLLLEDGCEVTVGRGFGVTYQLVSKICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLENKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDELAGPGAEGPSNLKSKINKVSCESGQPVKSQGKGEVASTPSDNLDPKLTALEPSKTTGAPIYPGFPKVTEVHHEQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKGNSKKVVQMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGLEIAQGEKDLKQQLAQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERKAKRLF
Homo sapiens
Nucleus, Cytoplasm, Midbody, Chromosome, telomere
Low tissue specificity
{'Ciliated cells': '32.7', 'Basal respiratory cells': '25.8', 'Club cells': '21.1', 'Ionocytes': '14.7', 'Mucus glandular cells': '22.1', 'Serous glandular cells': '22.6', 'Gastric mucus-secreting cells': '17.7', 'Proximal enterocytes': '10.5', 'Paneth cells': '15.1', 'Distal enterocytes': '10.0', 'Intestinal goblet cells': '16.0', 'Exocrine glandular cells': '-0.639', 'Basal prostatic cells': '20.0', 'Prostatic glandular cells': '17.9', 'Breast glandular cells': '0.548', 'Breast myoepithelial cells': '0.568', 'Glandular and luminal cells': '55.4', 'Secretory cells': '20.7', 'Basal keratinocytes': '26.6', 'Suprabasal keratinocytes': '36.6', 'Basal squamous epithelial cells': '26.4', 'Squamous epithelial cells': '35.6', 'Alveolar cells type 1': '0.317', 'Alveolar cells type 2': '-0.116', 'Salivary duct cells': '32.2', 'Ductal cells': '0.590', 'Hepatocytes': '0.475', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.086', 'Distal tubular cells': '24.6', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.464', 'Sertoli cells': '0.410', 'Granulosa cells': '33.8', 'Enteroendocrine cells': '22.9', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '0.234', 'Excitatory neurons': '16.4', 'Inhibitory neurons': '15.3', 'Cone photoreceptor cells': '23.8', 'Rod photoreceptor cells': '28.9', 'Bipolar cells': '24.0', 'Horizontal cells': '33.4', 'Astrocytes': '12.7', 'Oligodendrocyte precursor cells': '11.8', 'Oligodendrocytes': '19.1', 'Microglial cells': '10.7', 'Muller glia cells': '24.2', 'Schwann cells': '0.051', 'Spermatogonia': '0.378', 'Spermatocytes': '0.279', 'Early spermatids': '0.119', 'Late spermatids': '-0.231', 'Oocytes': '48.5', 'Cytotrophoblasts': '26.4', 'Syncytiotrophoblasts': '4.6', 'Extravillous trophoblasts': '26.8', 'Endothelial cells': '19.7', 'Lymphatic endothelial cells': '20.6', 'Cardiomyocytes': '0.619', 'Skeletal myocytes': '-0.121', 'Smooth muscle cells': '23.0', 'Adipocytes': '20.2', 'Melanocytes': '0.232', 'Fibroblasts': '24.9', 'Peritubular cells': '0.077', 'Endometrial stromal cells': '33.0', 'Ovarian stromal cells': '30.3', 'Undifferentiated cells': '21.0', 'T-cells': '18.9', 'B-cells': '16.3', 'Plasma cells': '14.9', 'Nk-cells': '29.2', 'Granulocytes': '26.0', 'Monocytes': '7.6', 'Macrophages': '12.8', 'Hofbauer cells': '17.3', 'Kupffer cells': '11.9', 'Dendritic cells': '2.4', 'Langerhans cells': '0.124', 'Erythroid cells': '-0.012', 'Adipocytes (Subcutaneous)': '-0.436', 'Adipocytes (Visceral)': '-0.390', 'Breast glandular cells (progenitors)': '0.348', 'Adipocytes (Breast)': '-0.563', 'Colon enterocytes': '-0.240', 'Colon enteroendocrine cells': '0.233', 'Enteric glia cells': '0.133', 'Mitotic cells (Colon)': '-0.099', 'Mitotic cells (Heart)': '0.484', 'Podocytes': '-0.044', 'Ascending Loop of Henle cells': '0.513', 'Intercalated cells': '-0.001', 'Cholangiocyte': '0.376', 'NK-cells (Liver)': '-0.277', 'Respiratory ciliated cells': '0.004', 'Mitotic cells (Lung)': '0.045', 'NK-cells (Lung)': '0.113', 'B-cells (Lung)': '-0.101', 'Alpha cells': '0.425', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '0.127', 'Urothelial cells': '0.140', 'Keratinocyte (other)': '0.153', 'Keratinocyte (granular)': '-0.072', 'Hair cortex cells': '0.151', 'Inner root sheath cells': '0.238', 'Outer root sheath cells': '0.191', 'Sebaceous gland cells': '-0.083', 'Eccrine sweat gland cells': '-0.018', 'Adipocytes (Skin)': '-0.127', 'Mitotic cells (Skin)': '0.363', 'Parietal cells': '-0.661', 'Chief cells': '-0.525', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.388', 'Mitotic cells (Stomach)': '0.107', 'Parafollicular cells': '0.052', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '0.048', 'Adrenal cortex cells': '0.419', 'Adrenal medulla cells': '-0.060', 'Mitotic cells (Adrenal gland)': '0.248', 'Minor salivary glandular cells': '0.280', 'Minor salivary gland ductal cells': '-0.198', 'Minor salivary gland basal cells': '0.681', 'Mitotic cells (Minor salivary gland)': '0.719', 'Adipocytes (Minor salivary gland)': '0.238', 'Somatotropes': '-0.119', 'Lactotropes': '-0.073', 'Gonadotropes': '-0.014', 'Corticotropes': '-0.061', 'Thyrotropes': '0.233', 'Undifferentiated cells (Pituitary gland)': '0.337', 'Mitotic cells (Spleen)': '-0.155', 'Platelets': '-0.175', 'Erythrocytes': '-0.025', 'Hematopoietic stem cells': '-0.189', 'B-cells (Spleen)': '0.376', 'NK-cells (Spleen)': '0.258', 'Amygdala excitatory': '29.0', 'Cerebellar inhibitory': '39.4', 'Cge interneuron': '30.6', 'Deep-layer corticothalamic and 6b': '32.4', 'Deep-layer intratelencephalic': '28.1', 'Deep-layer near-projecting': '24.6', 'Eccentric medium spiny neuron': '32.5', 'Hippocampal ca1-3': '25.5', 'Hippocampal ca4': '28.2', 'Hippocampal dentate gyrus': '28.6', 'Lamp5-lhx6 and chandelier': '37.6', 'Lower rhombic lip': '16.6', 'Mammillary body': '30.7', 'Medium spiny neuron': '28.0', 'Mge interneuron': '25.4', 'Midbrain-derived inhibitory': '31.2', 'Miscellaneous': '25.9', 'Splatter': '26.5', 'Thalamic excitatory': '31.9', 'Upper rhombic lip': '39.0', 'Upper-layer intratelencephalic': '31.1', 'Astrocyte': '27.4', 'Bergmann glia': '29.1', 'Central nervous system macrophage': '21.1', 'Choroid plexus epithelial cell': '30.8', 'Committed oligodendrocyte precursor': '23.7', 'Ependymal cell': '22.5', 'Oligodendrocyte': '35.3', 'Oligodendrocyte precursor cell': '24.5', 'Endothelial cell': '34.2', 'Pericyte': '18.1', 'Vascular associated smooth muscle cell': '19.0', 'Fibroblast': '21.5', 'Leukocyte': '23.3', 'Basophil': '1.5', 'Eosinophil': '2.5', 'Neutrophil': '1.5', 'Classical monocyte': '3.7', 'Non-classical monocyte': '5.5', 'Intermediate monocyte': '8.2', 'T-reg': '7.3', 'GdT-cell': '9.5', 'MAIT T-cell': '7.7', 'Memory CD4 T-cell': '7.0', 'Naive CD4 T-cell': '10.8', 'Memory CD8 T-cell': '9.1', 'Naive CD8 T-cell': '8.8', 'Memory B-cell': '8.1', 'Naive B-cell': '6.3', 'Plasmacytoid DC': '3.8', 'Myeloid DC': '6.4', 'NK-cell': '13.1', 'Total PBMC': '9.1', 'Vd2 gdTCR': '11.1', 'Memory CD4 T-cell Th1\\/Th17': '10.8', 'Memory CD4 T-cell Th17': '10.8', 'Memory CD4 T-cell Th2': '9.7', 'Non-Vd2 gdTCR': '10.4', 'Memory CD4 T-cell Th1': '10.4', 'Memory CD4 T-cell TFH': '10.4', 'Terminal effector memory CD4 T-cell': '6.4', 'Central memory CD8 T-cell': '7.0', 'Effector memory CD8 T-cell': '8.2', 'Terminal effector memory CD8 T-cell': '10.0', 'Non-switched memory B-cell': '9.8', 'Plasmablast': '10.4', 'Switched memory B-cell': '6.9', 'Exhausted memory B-cell': '7.2', 'Progenitor cell': '9.2', 'Memory T-reg': '10.2', 'Naive CD4 T-cell activated': '6.2', 'Naive CD8 T-cell activated': '8.5', 'Naive T-reg': '10.5'}
2CSW, 2PIE, 4AYC, 4ORH, 4WHV
{'Adipose Tissue': 5.842281561461794, 'Adrenal Gland': 7.026077519379845, 'Bladder': 7.759809523809524, 'Blood': 3.220500215285253, 'Blood Vessel': 8.356130337078651, 'Brain': 7.779572937168812, 'Breast': 6.3104291938997825, 'Cervix Uteri': 9.987631578947369, 'Colon': 6.505412066752247, 'Esophagus': 8.088813840830449, 'Fallopian Tube': 9.497888888888887, 'Heart': 4.124628919860627, 'Kidney': 4.606573033707865, 'Liver': 2.3945101769911505, 'Lung': 7.91575259515571, 'Muscle': 4.271328767123288, 'Nerve': 8.343988691437803, 'Ovary': 10.546722222222222, 'Pancreas': 2.164347865853659, 'Pituitary': 8.595367491166078, 'Prostate': 8.065632653061224, 'Salivary Gland': 6.157123456790123, 'Skin': 8.770229961304588, 'Small Intestine': 5.831320855614974, 'Spleen': 5.645, 'Stomach': 4.767988857938719, 'Testis': 19.702216066481995, 'Thyroid': 6.970906584992344, 'Uterus': 10.236056338028169, 'Vagina': 10.048794871794872}
NBN
MWKLLPAAGPAGGEPYRLLTGVEYVVGRKNCAILIENDQSISRNHAVLTANFSVTNLSQTDEIPVLTLKDNSKYGTFVNEEKMQNGFSRTLKSGDGITFGVFGSKFRIEYEPLVACSSCLDVSGKTALNQAILQLGGFTVNNWTEECTHLVMVSVKVTIKTICALICGRPIVKPEYFTEFLKAVESKKQPPQIESFYPPLDEPSIGSKNVDLSGRQERKQIFKGKTFIFLNAKQHKKLSSAVVFGGGEARLITEENEEEHNFFLAPGTCVVDTGITNSQTLIPDCQKKWIQSIMDMLQRQGLRPIPEAEIGLAVIFMTTKNYCDPQGHPSTGLKTTTPGPSLSQGVSVDEKLMPSAPVNTTTYVADTESEQADTWDLSERPKEIKVSKMEQKFRMLSQDAPTVKESCKTSSNNNSMVSNTLAKMRIPNYQLSPTKLPSINKSKDRASQQQQTNSIRNYFQPSTKKRERDEENQEMSSCKSARIETSCSLLEQTQPATPSLWKNKEQHLSENEPVDTNSDNNLFTDTDLKSIVKNSASKSHAAEKLRSNKKREMDDVAIEDEVLEQLFKDTKPELEIDVKVQKQEEDVNVRKRPRMDIETNDTFSDEAVPESSKISQENEIGKKRELKEDSLWSAKEISNNDKLQDDSEMLPKKLLLTEFRSLVIKNSTSRNPSGINDDYGQLKNFKKFKKVTYPGAGKLPHIIGGSDLIAHHARKNTELEEWLRQEMEVQNQHAKEESLADDLFRYNPYLKRRR
Homo sapiens
Nucleus, Chromosome, Nucleus, PML body, Chromosome, telomere
Low tissue specificity
{'Ciliated cells': '33.8', 'Basal respiratory cells': '19.1', 'Club cells': '27.1', 'Ionocytes': '16.2', 'Mucus glandular cells': '33.7', 'Serous glandular cells': '33.3', 'Gastric mucus-secreting cells': '19.5', 'Proximal enterocytes': '9.2', 'Paneth cells': '9.8', 'Distal enterocytes': '12.8', 'Intestinal goblet cells': '17.1', 'Exocrine glandular cells': '-0.560', 'Basal prostatic cells': '25.7', 'Prostatic glandular cells': '35.0', 'Breast glandular cells': '0.396', 'Breast myoepithelial cells': '0.423', 'Glandular and luminal cells': '33.6', 'Secretory cells': '38.1', 'Basal keratinocytes': '19.9', 'Suprabasal keratinocytes': '28.6', 'Basal squamous epithelial cells': '28.8', 'Squamous epithelial cells': '30.2', 'Alveolar cells type 1': '0.099', 'Alveolar cells type 2': '0.152', 'Salivary duct cells': '28.3', 'Ductal cells': '0.599', 'Hepatocytes': '0.498', 'Cholangiocytes': '11.4', 'Proximal tubular cells': '0.242', 'Distal tubular cells': '27.7', 'Collecting duct cells': '27.2', 'Mesothelial cells': '0.408', 'Sertoli cells': '0.378', 'Granulosa cells': '34.6', 'Enteroendocrine cells': '19.7', 'Pancreatic endocrine cells': '18.7', 'Leydig cells': '0.481', 'Excitatory neurons': '43.5', 'Inhibitory neurons': '38.2', 'Cone photoreceptor cells': '5.1', 'Rod photoreceptor cells': '8.1', 'Bipolar cells': '20.2', 'Horizontal cells': '15.1', 'Astrocytes': '23.2', 'Oligodendrocyte precursor cells': '38.2', 'Oligodendrocytes': '37.5', 'Microglial cells': '31.3', 'Muller glia cells': '23.9', 'Schwann cells': '0.139', 'Spermatogonia': '0.566', 'Spermatocytes': '0.392', 'Early spermatids': '-0.032', 'Late spermatids': '-0.508', 'Oocytes': '22.1', 'Cytotrophoblasts': '23.8', 'Syncytiotrophoblasts': '10.5', 'Extravillous trophoblasts': '20.6', 'Endothelial cells': '24.9', 'Lymphatic endothelial cells': '23.7', 'Cardiomyocytes': '0.607', 'Skeletal myocytes': '-0.094', 'Smooth muscle cells': '30.1', 'Adipocytes': '34.2', 'Melanocytes': '0.112', 'Fibroblasts': '35.6', 'Peritubular cells': '0.392', 'Endometrial stromal cells': '47.3', 'Ovarian stromal cells': '39.3', 'Undifferentiated cells': '23.2', 'T-cells': '34.8', 'B-cells': '32.7', 'Plasma cells': '48.4', 'Nk-cells': '37.7', 'Granulocytes': '66.4', 'Monocytes': '359.0', 'Macrophages': '46.3', 'Hofbauer cells': '28.2', 'Kupffer cells': '22.5', 'Dendritic cells': '12.9', 'Langerhans cells': '0.255', 'Erythroid cells': '-0.063', 'Adipocytes (Subcutaneous)': '-0.046', 'Adipocytes (Visceral)': '-0.167', 'Breast glandular cells (progenitors)': '0.218', 'Adipocytes (Breast)': '-0.276', 'Colon enterocytes': '-0.097', 'Colon enteroendocrine cells': '0.189', 'Enteric glia cells': '-0.152', 'Mitotic cells (Colon)': '-0.027', 'Mitotic cells (Heart)': '0.498', 'Podocytes': '-0.030', 'Ascending Loop of Henle cells': '0.425', 'Intercalated cells': '0.015', 'Cholangiocyte': '0.313', 'NK-cells (Liver)': '-0.271', 'Respiratory ciliated cells': '-0.045', 'Mitotic cells (Lung)': '0.176', 'NK-cells (Lung)': '0.018', 'B-cells (Lung)': '-0.119', 'Alpha cells': '0.342', 'Beta cells': '0.163', 'Prostate glandular cells': '-0.238', 'Prostate basal glandular cells': '0.047', 'Urothelial cells': '0.033', 'Keratinocyte (other)': '0.025', 'Keratinocyte (granular)': '-0.314', 'Hair cortex cells': '0.093', 'Inner root sheath cells': '0.155', 'Outer root sheath cells': '0.349', 'Sebaceous gland cells': '0.273', 'Eccrine sweat gland cells': '0.242', 'Adipocytes (Skin)': '0.076', 'Mitotic cells (Skin)': '0.414', 'Parietal cells': '-0.687', 'Chief cells': '-0.611', 'Gastric mucous cells': '-0.455', 'Gastric enteroendocrine cells': '-0.479', 'Mitotic cells (Stomach)': '0.043', 'Parafollicular cells': '0.130', 'Thyroid glandular cells': '0.595', 'Mitotic cells (Thyroid)': '0.118', 'Adrenal cortex cells': '0.664', 'Adrenal medulla cells': '0.123', 'Mitotic cells (Adrenal gland)': '0.486', 'Minor salivary glandular cells': '0.303', 'Minor salivary gland ductal cells': '0.318', 'Minor salivary gland basal cells': '0.223', 'Mitotic cells (Minor salivary gland)': '0.270', 'Adipocytes (Minor salivary gland)': '0.085', 'Somatotropes': '0.206', 'Lactotropes': '-0.234', 'Gonadotropes': '-0.087', 'Corticotropes': '-0.292', 'Thyrotropes': '-0.130', 'Undifferentiated cells (Pituitary gland)': '0.185', 'Mitotic cells (Spleen)': '0.032', 'Platelets': '-0.046', 'Erythrocytes': '-0.035', 'Hematopoietic stem cells': '-0.134', 'B-cells (Spleen)': '0.239', 'NK-cells (Spleen)': '0.264', 'Amygdala excitatory': '65.3', 'Cerebellar inhibitory': '50.0', 'Cge interneuron': '40.6', 'Deep-layer corticothalamic and 6b': '45.2', 'Deep-layer intratelencephalic': '49.6', 'Deep-layer near-projecting': '41.2', 'Eccentric medium spiny neuron': '70.9', 'Hippocampal ca1-3': '74.3', 'Hippocampal ca4': '53.8', 'Hippocampal dentate gyrus': '83.7', 'Lamp5-lhx6 and chandelier': '61.7', 'Lower rhombic lip': '43.5', 'Mammillary body': '62.0', 'Medium spiny neuron': '101.2', 'Mge interneuron': '60.7', 'Midbrain-derived inhibitory': '52.2', 'Miscellaneous': '56.4', 'Splatter': '52.3', 'Thalamic excitatory': '51.7', 'Upper rhombic lip': '47.1', 'Upper-layer intratelencephalic': '72.5', 'Astrocyte': '49.4', 'Bergmann glia': '63.1', 'Central nervous system macrophage': '53.6', 'Choroid plexus epithelial cell': '26.0', 'Committed oligodendrocyte precursor': '50.8', 'Ependymal cell': '45.3', 'Oligodendrocyte': '71.3', 'Oligodendrocyte precursor cell': '60.0', 'Endothelial cell': '45.7', 'Pericyte': '59.7', 'Vascular associated smooth muscle cell': '42.5', 'Fibroblast': '63.3', 'Leukocyte': '48.9', 'Basophil': '18.3', 'Eosinophil': '16.8', 'Neutrophil': '189.9', 'Classical monocyte': '40.5', 'Non-classical monocyte': '80.9', 'Intermediate monocyte': '49.8', 'T-reg': '9.4', 'GdT-cell': '5.2', 'MAIT T-cell': '18.6', 'Memory CD4 T-cell': '5.6', 'Naive CD4 T-cell': '34.8', 'Memory CD8 T-cell': '5.5', 'Naive CD8 T-cell': '29.0', 'Memory B-cell': '9.6', 'Naive B-cell': '44.4', 'Plasmacytoid DC': '20.7', 'Myeloid DC': '26.4', 'NK-cell': '45.4', 'Total PBMC': '19.0', 'Vd2 gdTCR': '16.0', 'Memory CD4 T-cell TFH': '27.4', 'Memory CD4 T-cell Th2': '28.2', 'Memory CD4 T-cell Th17': '30.8', 'Memory CD4 T-cell Th1\\/Th17': '42.8', 'Non-Vd2 gdTCR': '20.1', 'Memory CD4 T-cell Th1': '30.9', 'Terminal effector memory CD4 T-cell': '21.6', 'Central memory CD8 T-cell': '12.8', 'Effector memory CD8 T-cell': '14.1', 'Terminal effector memory CD8 T-cell': '14.3', 'Switched memory B-cell': '13.4', 'Plasmablast': '25.9', 'Non-switched memory B-cell': '10.6', 'Exhausted memory B-cell': '18.8', 'Progenitor cell': '34.2', 'Memory T-reg': '19.8', 'Naive CD4 T-cell activated': '51.7', 'Naive CD8 T-cell activated': '50.3', 'Naive T-reg': '31.2'}
5WQD, 7SID, 8BAH
{'Adipose Tissue': 17.317490033222594, 'Adrenal Gland': 12.429961240310076, 'Bladder': 17.752380952380953, 'Blood': 21.698388159311087, 'Blood Vessel': 19.194573033707865, 'Brain': 10.0807963663891, 'Breast': 17.97827450980392, 'Cervix Uteri': 23.347368421052632, 'Colon': 22.94196405648267, 'Esophagus': 30.44680830449827, 'Fallopian Tube': 22.077777777777776, 'Heart': 6.2083454123112665, 'Kidney': 9.931629213483143, 'Liver': 6.980986725663716, 'Lung': 21.865846020761246, 'Muscle': 7.840823163138231, 'Nerve': 38.12250403877221, 'Ovary': 19.681805555555556, 'Pancreas': 6.822875, 'Pituitary': 17.67214487632509, 'Prostate': 17.72652244897959, 'Salivary Gland': 15.560814814814814, 'Skin': 17.925264787175234, 'Small Intestine': 18.951005347593583, 'Spleen': 19.13919917012448, 'Stomach': 12.032554317548746, 'Testis': 13.986817174515236, 'Thyroid': 20.844704441041348, 'Uterus': 38.79978873239436, 'Vagina': 19.381352564102563}
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[0.02, 0.05, 0.13, 0.01, 0.32, 0.16, 0.55, 0.72, 0.38, 0.84, 0.88, 0.5, 0.46, 0.54, 0.26, 0.3, 0.2, 0.03, 0.07, 0.18, 0.64, 0.39, 0.69, 0.14, 0.28, 0.0, 0.0, 0.44, 0.74, 0.96, 0.24, 0.3, 0.0, 0.43, 0.08, 0.74, 0.92, 0.08, 0.76, 0.03, 0.02, 0.2, 0.76, 0.46, 0.0, 0.0, 0.14, 0.02, 0.12, 0.03, 0.46, 0.28, 0.4, 0.88, 0.82, 0.34, 0.78, 0.86, 0.62, 0.35, 0.75, 0.31, 0.58, 0.01, 0.41, 0.01, 0.31, 0.0, 0.41, 0.01, 0.34, 0.07, 0.93, 0.44, 0.03, 0.0, 0.2, 0.0, 0.58, 0.63, 0.55, 0.57, 0.11, 0.69, 0.56, 0.48, 0.6, 0.69, 0.32, 0.65, 0.04, 0.74, 0.55, 0.41, 0.15, 0.27, 0.02, 0.09, 0.0, 0.01, 0.59, 0.62, 0.81, 0.09, 0.41, 0.12, 0.58, 0.01, 0.39, 0.16, 0.47, 0.57, 0.1, 0.03, 0.01, 0.0, 0.09, 0.08, 0.61, 0.11, 0.62, 0.75, 0.63, 0.22, 0.43, 0.57, 0.49, 0.04, 0.37, 0.59, 0.06, 0.01, 0.28, 0.32, 0.0, 0.01, 0.01, 0.12, 0.27, 0.11, 0.74, 0.73, 0.1, 0.48, 0.58, 0.61, 0.0, 0.18, 0.11, 0.0, 0.0, 0.0, 0.52, 0.22, 0.04, 0.38, 0.26, 0.21, 0.24, 0.19, 0.02, 0.05, 0.01, 0.0, 0.02, 0.0, 0.06, 0.25, 0.37, 0.27, 0.07, 0.0, 0.35, 0.17, 0.54, 0.05, 0.0, 0.36, 0.42, 0.09, 0.11, 0.47, 0.09, 0.12, 0.58, 0.48, 0.68, 0.67, 0.75, 0.4, 0.22, 0.73, 0.28, 0.64, 0.76, 0.16, 0.46, 0.14, 0.52, 0.49, 0.47, 0.18, 0.72, 0.29, 0.13, 0.51, 0.97, 0.7, 0.87, 0.17, 0.35, 0.28, 0.47, 0.47, 0.37, 0.5, 0.54, 0.01, 0.33, 0.52, 0.14, 0.0, 0.66, 0.73, 0.17, 0.16, 0.0, 0.0, 0.0, 0.0, 0.2, 0.49, 0.71, 0.11, 0.23, 0.87, 0.36, 0.03, 0.21, 0.3, 0.0, 0.0, 0.6, 0.2, 0.0, 0.35, 0.14, 0.46, 0.27, 0.36, 0.4, 0.02, 0.29, 0.4, 0.91, 0.69, 0.68, 0.44, 0.7, 0.64, 0.64, 0.22, 0.04, 0.36, 0.39, 0.91, 0.27, 0.07, 0.01, 0.02, 0.0, 0.18, 0.12, 0.39, 0.31, 0.48, 0.91, 0.79, 0.5, 0.68, 0.74, 0.19, 0.58, 0.57, 0.48, 0.26, 0.28, 0.7, 0.1, 0.06, 0.55, 0.54, 0.07, 0.19, 0.36, 0.13, 0.02, 0.73, 0.7, 0.62, 0.55, 0.18, 0.22, 0.3, 0.0, 0.23, 0.19, 0.37, 0.13, 0.0, 0.1, 0.2, 0.0, 0.0, 0.1, 0.39, 0.33, 0.22, 0.21, 0.83, 0.71, 0.26, 0.0, 0.26, 0.12, 0.73, 0.22, 0.81, 0.76, 0.73, 0.61, 0.85, 0.93, 0.77, 0.81, 0.88, 0.88, 0.87, 0.9, 0.9, 0.9, 0.9, 0.91, 0.97, 0.97, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.98, 1.0, 0.96, 0.99, 0.99, 0.96, 0.98, 0.95, 0.99, 0.96, 1.0, 1.0, 0.84, 1.0, 0.88, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 1.0, 0.94, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.97, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 0.99, 0.97, 1.0, 0.99, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.95, 0.99, 0.93, 0.97, 0.96, 0.93, 0.97, 0.93, 0.84, 0.68, 0.83, 0.85, 0.84, 0.87, 0.84, 0.91, 0.9, 0.96, 0.95, 0.97, 0.8, 0.94, 0.88, 0.97, 0.99, 0.97, 1.0, 0.95, 0.99, 0.9, 0.98, 0.95, 0.97, 0.8, 0.89, 0.8, 0.81, 0.47, 0.74, 0.73, 0.63, 0.54, 0.86, 0.8, 0.87, 0.8, 0.9, 0.88, 0.96, 0.93, 0.82, 0.92, 0.74, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 1.0, 0.9, 0.85, 0.93, 0.74, 0.98, 0.95, 0.99, 0.96, 1.0, 1.0, 1.0, 1.0, 0.97, 0.97, 0.98, 0.87, 1.0, 0.95, 0.99, 0.99, 0.97, 1.0, 0.95, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.73, 1.0, 0.82, 1.0, 0.98, 0.96, 0.99, 0.97, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 0.99, 0.94, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.94, 0.7, 0.81, 0.77, 0.61, 0.76, 0.64, 0.72, 0.56, 0.49, 0.55, 0.5, 0.63, 0.72, 0.55, 0.74, 0.75, 0.86, 0.91, 0.97, 0.92, 0.98, 0.87, 0.66, 0.74, 0.72, 0.81, 0.86, 0.79, 0.92, 0.82, 1.0, 0.99, 0.91, 0.98, 0.91, 1.0, 0.96, 1.0, 0.95, 0.91, 0.95, 0.82, 0.93, 1.0, 1.0, 1.0, 0.97, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.99, 0.99, 0.99, 0.96, 0.99, 0.94, 0.91, 0.99, 0.91, 0.99, 0.89, 0.91, 0.95, 0.84, 0.98, 0.93, 0.97, 0.8, 0.92, 0.81, 0.97, 0.9, 0.96, 0.94, 0.85, 0.76, 0.74, 0.34, 0.89, 0.92, 0.7, 0.69, 0.65, 0.93, 0.78, 0.87, 0.93, 0.69, 0.65, 0.87, 0.73, 0.65, 0.89, 0.76, 0.86, 0.86, 0.79, 0.84, 0.86, 0.81, 0.96, 0.85, 0.91, 0.9, 0.92, 0.88, 0.97, 0.74, 0.92, 0.87, 0.87, 0.92, 0.92, 0.77, 0.92, 0.62, 0.79, 0.72, 0.78, 0.87, 0.85, 0.83, 0.82, 0.67, 0.99, 0.73, 0.38, 0.76, 0.91, 0.89, 0.72, 0.72, 0.82, 0.61, 0.37, 0.94, 0.79, 0.66, 0.76, 0.86, 0.73, 0.88, 0.81, 0.72, 0.86, 0.71, 0.49, 0.52, 0.77, 0.5, 0.42, 0.58, 0.56, 0.59, 0.55, 0.63, 0.4, 0.7, 0.52, 0.38, 0.55, 0.45, 0.49, 0.59, 0.51, 0.54, 0.67, 0.61, 0.51, 0.62, 0.34, 0.42, 0.6, 0.66, 0.83, 0.68, 0.74, 0.53, 0.71, 0.89, 0.74, 0.9, 0.94, 0.97, 0.99]
RING finger
null
null
null
RXRA,MDC1,HERC2, PIWIL1, WRAP53
H2A,H2AX, H2B, PCNA,CHEK2, JMJD2A , KU80, POLD4
63, 48
null
UBE2N, UBE2E1, UBE2E2, UBE2E3, UBE2V2, UBE2L6
Homodimer
null
74.943402
0.531773
63.431101
0.641552
898
O76064
O75164
22199232, UNIPROT
UbiNet, UbiBrowser, 31181401
RNF8
MGEPGFFVTGDRAGGRSWCLRRVGMSAGWLLLEDGCEVTVGRGFGVTYQLVSKICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLENKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDELAGPGAEGPSNLKSKINKVSCESGQPVKSQGKGEVASTPSDNLDPKLTALEPSKTTGAPIYPGFPKVTEVHHEQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKGNSKKVVQMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGLEIAQGEKDLKQQLAQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERKAKRLF
Homo sapiens
Nucleus, Cytoplasm, Midbody, Chromosome, telomere
Low tissue specificity
{'Ciliated cells': '32.7', 'Basal respiratory cells': '25.8', 'Club cells': '21.1', 'Ionocytes': '14.7', 'Mucus glandular cells': '22.1', 'Serous glandular cells': '22.6', 'Gastric mucus-secreting cells': '17.7', 'Proximal enterocytes': '10.5', 'Paneth cells': '15.1', 'Distal enterocytes': '10.0', 'Intestinal goblet cells': '16.0', 'Exocrine glandular cells': '-0.639', 'Basal prostatic cells': '20.0', 'Prostatic glandular cells': '17.9', 'Breast glandular cells': '0.548', 'Breast myoepithelial cells': '0.568', 'Glandular and luminal cells': '55.4', 'Secretory cells': '20.7', 'Basal keratinocytes': '26.6', 'Suprabasal keratinocytes': '36.6', 'Basal squamous epithelial cells': '26.4', 'Squamous epithelial cells': '35.6', 'Alveolar cells type 1': '0.317', 'Alveolar cells type 2': '-0.116', 'Salivary duct cells': '32.2', 'Ductal cells': '0.590', 'Hepatocytes': '0.475', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.086', 'Distal tubular cells': '24.6', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.464', 'Sertoli cells': '0.410', 'Granulosa cells': '33.8', 'Enteroendocrine cells': '22.9', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '0.234', 'Excitatory neurons': '16.4', 'Inhibitory neurons': '15.3', 'Cone photoreceptor cells': '23.8', 'Rod photoreceptor cells': '28.9', 'Bipolar cells': '24.0', 'Horizontal cells': '33.4', 'Astrocytes': '12.7', 'Oligodendrocyte precursor cells': '11.8', 'Oligodendrocytes': '19.1', 'Microglial cells': '10.7', 'Muller glia cells': '24.2', 'Schwann cells': '0.051', 'Spermatogonia': '0.378', 'Spermatocytes': '0.279', 'Early spermatids': '0.119', 'Late spermatids': '-0.231', 'Oocytes': '48.5', 'Cytotrophoblasts': '26.4', 'Syncytiotrophoblasts': '4.6', 'Extravillous trophoblasts': '26.8', 'Endothelial cells': '19.7', 'Lymphatic endothelial cells': '20.6', 'Cardiomyocytes': '0.619', 'Skeletal myocytes': '-0.121', 'Smooth muscle cells': '23.0', 'Adipocytes': '20.2', 'Melanocytes': '0.232', 'Fibroblasts': '24.9', 'Peritubular cells': '0.077', 'Endometrial stromal cells': '33.0', 'Ovarian stromal cells': '30.3', 'Undifferentiated cells': '21.0', 'T-cells': '18.9', 'B-cells': '16.3', 'Plasma cells': '14.9', 'Nk-cells': '29.2', 'Granulocytes': '26.0', 'Monocytes': '7.6', 'Macrophages': '12.8', 'Hofbauer cells': '17.3', 'Kupffer cells': '11.9', 'Dendritic cells': '2.4', 'Langerhans cells': '0.124', 'Erythroid cells': '-0.012', 'Adipocytes (Subcutaneous)': '-0.436', 'Adipocytes (Visceral)': '-0.390', 'Breast glandular cells (progenitors)': '0.348', 'Adipocytes (Breast)': '-0.563', 'Colon enterocytes': '-0.240', 'Colon enteroendocrine cells': '0.233', 'Enteric glia cells': '0.133', 'Mitotic cells (Colon)': '-0.099', 'Mitotic cells (Heart)': '0.484', 'Podocytes': '-0.044', 'Ascending Loop of Henle cells': '0.513', 'Intercalated cells': '-0.001', 'Cholangiocyte': '0.376', 'NK-cells (Liver)': '-0.277', 'Respiratory ciliated cells': '0.004', 'Mitotic cells (Lung)': '0.045', 'NK-cells (Lung)': '0.113', 'B-cells (Lung)': '-0.101', 'Alpha cells': '0.425', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '0.127', 'Urothelial cells': '0.140', 'Keratinocyte (other)': '0.153', 'Keratinocyte (granular)': '-0.072', 'Hair cortex cells': '0.151', 'Inner root sheath cells': '0.238', 'Outer root sheath cells': '0.191', 'Sebaceous gland cells': '-0.083', 'Eccrine sweat gland cells': '-0.018', 'Adipocytes (Skin)': '-0.127', 'Mitotic cells (Skin)': '0.363', 'Parietal cells': '-0.661', 'Chief cells': '-0.525', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.388', 'Mitotic cells (Stomach)': '0.107', 'Parafollicular cells': '0.052', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '0.048', 'Adrenal cortex cells': '0.419', 'Adrenal medulla cells': '-0.060', 'Mitotic cells (Adrenal gland)': '0.248', 'Minor salivary glandular cells': '0.280', 'Minor salivary gland ductal cells': '-0.198', 'Minor salivary gland basal cells': '0.681', 'Mitotic cells (Minor salivary gland)': '0.719', 'Adipocytes (Minor salivary gland)': '0.238', 'Somatotropes': '-0.119', 'Lactotropes': '-0.073', 'Gonadotropes': '-0.014', 'Corticotropes': '-0.061', 'Thyrotropes': '0.233', 'Undifferentiated cells (Pituitary gland)': '0.337', 'Mitotic cells (Spleen)': '-0.155', 'Platelets': '-0.175', 'Erythrocytes': '-0.025', 'Hematopoietic stem cells': '-0.189', 'B-cells (Spleen)': '0.376', 'NK-cells (Spleen)': '0.258', 'Amygdala excitatory': '29.0', 'Cerebellar inhibitory': '39.4', 'Cge interneuron': '30.6', 'Deep-layer corticothalamic and 6b': '32.4', 'Deep-layer intratelencephalic': '28.1', 'Deep-layer near-projecting': '24.6', 'Eccentric medium spiny neuron': '32.5', 'Hippocampal ca1-3': '25.5', 'Hippocampal ca4': '28.2', 'Hippocampal dentate gyrus': '28.6', 'Lamp5-lhx6 and chandelier': '37.6', 'Lower rhombic lip': '16.6', 'Mammillary body': '30.7', 'Medium spiny neuron': '28.0', 'Mge interneuron': '25.4', 'Midbrain-derived inhibitory': '31.2', 'Miscellaneous': '25.9', 'Splatter': '26.5', 'Thalamic excitatory': '31.9', 'Upper rhombic lip': '39.0', 'Upper-layer intratelencephalic': '31.1', 'Astrocyte': '27.4', 'Bergmann glia': '29.1', 'Central nervous system macrophage': '21.1', 'Choroid plexus epithelial cell': '30.8', 'Committed oligodendrocyte precursor': '23.7', 'Ependymal cell': '22.5', 'Oligodendrocyte': '35.3', 'Oligodendrocyte precursor cell': '24.5', 'Endothelial cell': '34.2', 'Pericyte': '18.1', 'Vascular associated smooth muscle cell': '19.0', 'Fibroblast': '21.5', 'Leukocyte': '23.3', 'Basophil': '1.5', 'Eosinophil': '2.5', 'Neutrophil': '1.5', 'Classical monocyte': '3.7', 'Non-classical monocyte': '5.5', 'Intermediate monocyte': '8.2', 'T-reg': '7.3', 'GdT-cell': '9.5', 'MAIT T-cell': '7.7', 'Memory CD4 T-cell': '7.0', 'Naive CD4 T-cell': '10.8', 'Memory CD8 T-cell': '9.1', 'Naive CD8 T-cell': '8.8', 'Memory B-cell': '8.1', 'Naive B-cell': '6.3', 'Plasmacytoid DC': '3.8', 'Myeloid DC': '6.4', 'NK-cell': '13.1', 'Total PBMC': '9.1', 'Vd2 gdTCR': '11.1', 'Memory CD4 T-cell Th1\\/Th17': '10.8', 'Memory CD4 T-cell Th17': '10.8', 'Memory CD4 T-cell Th2': '9.7', 'Non-Vd2 gdTCR': '10.4', 'Memory CD4 T-cell Th1': '10.4', 'Memory CD4 T-cell TFH': '10.4', 'Terminal effector memory CD4 T-cell': '6.4', 'Central memory CD8 T-cell': '7.0', 'Effector memory CD8 T-cell': '8.2', 'Terminal effector memory CD8 T-cell': '10.0', 'Non-switched memory B-cell': '9.8', 'Plasmablast': '10.4', 'Switched memory B-cell': '6.9', 'Exhausted memory B-cell': '7.2', 'Progenitor cell': '9.2', 'Memory T-reg': '10.2', 'Naive CD4 T-cell activated': '6.2', 'Naive CD8 T-cell activated': '8.5', 'Naive T-reg': '10.5'}
2CSW, 2PIE, 4AYC, 4ORH, 4WHV
{'Adipose Tissue': 5.842281561461794, 'Adrenal Gland': 7.026077519379845, 'Bladder': 7.759809523809524, 'Blood': 3.220500215285253, 'Blood Vessel': 8.356130337078651, 'Brain': 7.779572937168812, 'Breast': 6.3104291938997825, 'Cervix Uteri': 9.987631578947369, 'Colon': 6.505412066752247, 'Esophagus': 8.088813840830449, 'Fallopian Tube': 9.497888888888887, 'Heart': 4.124628919860627, 'Kidney': 4.606573033707865, 'Liver': 2.3945101769911505, 'Lung': 7.91575259515571, 'Muscle': 4.271328767123288, 'Nerve': 8.343988691437803, 'Ovary': 10.546722222222222, 'Pancreas': 2.164347865853659, 'Pituitary': 8.595367491166078, 'Prostate': 8.065632653061224, 'Salivary Gland': 6.157123456790123, 'Skin': 8.770229961304588, 'Small Intestine': 5.831320855614974, 'Spleen': 5.645, 'Stomach': 4.767988857938719, 'Testis': 19.702216066481995, 'Thyroid': 6.970906584992344, 'Uterus': 10.236056338028169, 'Vagina': 10.048794871794872}
KDM4A
MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFLKESELPPRAGNEEECPEEDMEGVEDGEEGDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEDLSSEQYEMTECPAALAPVRPTHSSVRQVEDGLTFPDYSDSTEVKFEELKNVKLEEEDEEEEQAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETSEPLSCRAQGQTGVLTVHSYAKGDGRVTVGEPCTRKKGSAARSFSERELAEVADEYMFSLEENKKSKGRRQPLSKLPRHHPLVLQECVSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQTYHQVEFGGFNQNCGNASDLAPQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME
Homo sapiens
Nucleus
Low tissue specificity
{'Ciliated cells': '13.8', 'Basal respiratory cells': '7.2', 'Club cells': '13.1', 'Ionocytes': '6.6', 'Mucus glandular cells': '10.9', 'Serous glandular cells': '11.4', 'Gastric mucus-secreting cells': '13.0', 'Proximal enterocytes': '15.4', 'Paneth cells': '13.4', 'Distal enterocytes': '24.5', 'Intestinal goblet cells': '16.2', 'Exocrine glandular cells': '-0.449', 'Basal prostatic cells': '12.7', 'Prostatic glandular cells': '14.6', 'Breast glandular cells': '0.568', 'Breast myoepithelial cells': '0.534', 'Glandular and luminal cells': '6.3', 'Secretory cells': '5.9', 'Basal keratinocytes': '11.2', 'Suprabasal keratinocytes': '9.7', 'Basal squamous epithelial cells': '8.2', 'Squamous epithelial cells': '10.1', 'Alveolar cells type 1': '0.071', 'Alveolar cells type 2': '0.303', 'Salivary duct cells': '14.1', 'Ductal cells': '0.600', 'Hepatocytes': '0.465', 'Cholangiocytes': '9.5', 'Proximal tubular cells': '0.268', 'Distal tubular cells': '0.0', 'Collecting duct cells': '1.9', 'Mesothelial cells': '0.446', 'Sertoli cells': '0.569', 'Granulosa cells': '10.5', 'Enteroendocrine cells': '10.8', 'Pancreatic endocrine cells': '3.4', 'Leydig cells': '0.619', 'Excitatory neurons': '20.6', 'Inhibitory neurons': '17.1', 'Cone photoreceptor cells': '11.9', 'Rod photoreceptor cells': '19.4', 'Bipolar cells': '15.3', 'Horizontal cells': '18.3', 'Astrocytes': '12.1', 'Oligodendrocyte precursor cells': '16.5', 'Oligodendrocytes': '22.1', 'Microglial cells': '5.4', 'Muller glia cells': '9.8', 'Schwann cells': '0.052', 'Spermatogonia': '0.594', 'Spermatocytes': '0.201', 'Early spermatids': '-0.521', 'Late spermatids': '-0.588', 'Oocytes': '2.2', 'Cytotrophoblasts': '7.3', 'Syncytiotrophoblasts': '7.9', 'Extravillous trophoblasts': '6.2', 'Endothelial cells': '7.8', 'Lymphatic endothelial cells': '7.1', 'Cardiomyocytes': '0.649', 'Skeletal myocytes': '-0.102', 'Smooth muscle cells': '6.9', 'Adipocytes': '4.7', 'Melanocytes': '0.376', 'Fibroblasts': '7.8', 'Peritubular cells': '0.549', 'Endometrial stromal cells': '8.4', 'Ovarian stromal cells': '6.2', 'Undifferentiated cells': '12.7', 'T-cells': '6.8', 'B-cells': '6.3', 'Plasma cells': '8.0', 'Nk-cells': '8.9', 'Granulocytes': '5.5', 'Monocytes': '4.6', 'Macrophages': '7.9', 'Hofbauer cells': '7.5', 'Kupffer cells': '9.5', 'Dendritic cells': '13.0', 'Langerhans cells': '0.467', 'Erythroid cells': '-0.087', 'Adipocytes (Subcutaneous)': '0.004', 'Adipocytes (Visceral)': '-0.111', 'Breast glandular cells (progenitors)': '0.472', 'Adipocytes (Breast)': '-0.440', 'Colon enterocytes': '0.147', 'Colon enteroendocrine cells': '0.073', 'Enteric glia cells': '-0.308', 'Mitotic cells (Colon)': '0.143', 'Mitotic cells (Heart)': '0.481', 'Podocytes': '-0.171', 'Ascending Loop of Henle cells': '0.520', 'Intercalated cells': '0.045', 'Cholangiocyte': '0.137', 'NK-cells (Liver)': '-0.119', 'Respiratory ciliated cells': '0.067', 'Mitotic cells (Lung)': '0.256', 'NK-cells (Lung)': '-0.131', 'B-cells (Lung)': '-0.182', 'Alpha cells': '0.415', 'Beta cells': '0.284', 'Prostate glandular cells': '0.150', 'Prostate basal glandular cells': '0.452', 'Urothelial cells': '0.255', 'Keratinocyte (other)': '0.629', 'Keratinocyte (granular)': '-0.059', 'Hair cortex cells': '-0.087', 'Inner root sheath cells': '-0.013', 'Outer root sheath cells': '0.158', 'Sebaceous gland cells': '0.036', 'Eccrine sweat gland cells': '-0.191', 'Adipocytes (Skin)': '-0.371', 'Mitotic cells (Skin)': '0.522', 'Parietal cells': '-0.225', 'Chief cells': '-0.288', 'Gastric mucous cells': '0.085', 'Gastric enteroendocrine cells': '-0.178', 'Mitotic cells (Stomach)': '0.403', 'Parafollicular cells': '0.066', 'Thyroid glandular cells': '0.551', 'Mitotic cells (Thyroid)': '0.028', 'Adrenal cortex cells': '0.719', 'Adrenal medulla cells': '-0.015', 'Mitotic cells (Adrenal gland)': '0.486', 'Minor salivary glandular cells': '0.537', 'Minor salivary gland ductal cells': '0.191', 'Minor salivary gland basal cells': '0.273', 'Mitotic cells (Minor salivary gland)': '0.349', 'Adipocytes (Minor salivary gland)': '0.089', 'Somatotropes': '-0.262', 'Lactotropes': '-0.069', 'Gonadotropes': '0.174', 'Corticotropes': '-0.042', 'Thyrotropes': '0.164', 'Undifferentiated cells (Pituitary gland)': '0.476', 'Mitotic cells (Spleen)': '-0.010', 'Platelets': '0.009', 'Erythrocytes': '-0.071', 'Hematopoietic stem cells': '-0.124', 'B-cells (Spleen)': '0.260', 'NK-cells (Spleen)': '0.326', 'Amygdala excitatory': '33.5', 'Cerebellar inhibitory': '35.6', 'Cge interneuron': '27.4', 'Deep-layer corticothalamic and 6b': '28.7', 'Deep-layer intratelencephalic': '30.9', 'Deep-layer near-projecting': '26.5', 'Eccentric medium spiny neuron': '38.2', 'Hippocampal ca1-3': '37.5', 'Hippocampal ca4': '25.0', 'Hippocampal dentate gyrus': '33.5', 'Lamp5-lhx6 and chandelier': '20.8', 'Lower rhombic lip': '31.3', 'Mammillary body': '29.4', 'Medium spiny neuron': '42.8', 'Mge interneuron': '29.3', 'Midbrain-derived inhibitory': '30.2', 'Miscellaneous': '32.2', 'Splatter': '25.4', 'Thalamic excitatory': '25.1', 'Upper rhombic lip': '27.1', 'Upper-layer intratelencephalic': '40.3', 'Astrocyte': '31.4', 'Bergmann glia': '26.7', 'Central nervous system macrophage': '39.0', 'Choroid plexus epithelial cell': '35.3', 'Committed oligodendrocyte precursor': '32.8', 'Ependymal cell': '39.3', 'Oligodendrocyte': '40.6', 'Oligodendrocyte precursor cell': '33.7', 'Endothelial cell': '25.7', 'Pericyte': '20.2', 'Vascular associated smooth muscle cell': '22.8', 'Fibroblast': '26.9', 'Leukocyte': '31.4', 'Basophil': '78.0', 'Eosinophil': '9.0', 'Neutrophil': '22.6', 'Classical monocyte': '24.7', 'Non-classical monocyte': '27.2', 'Intermediate monocyte': '26.0', 'T-reg': '20.1', 'GdT-cell': '4.4', 'MAIT T-cell': '23.5', 'Memory CD4 T-cell': '4.3', 'Naive CD4 T-cell': '29.9', 'Memory CD8 T-cell': '3.6', 'Naive CD8 T-cell': '27.2', 'Memory B-cell': '4.3', 'Naive B-cell': '38.4', 'Plasmacytoid DC': '25.9', 'Myeloid DC': '26.2', 'NK-cell': '49.3', 'Total PBMC': '21.0', 'Vd2 gdTCR': '20.0', 'Memory CD4 T-cell Th1\\/Th17': '36.0', 'Memory CD4 T-cell Th17': '39.0', 'Memory CD4 T-cell Th2': '40.8', 'Non-Vd2 gdTCR': '25.2', 'Memory CD4 T-cell Th1': '39.3', 'Memory CD4 T-cell TFH': '42.7', 'Terminal effector memory CD4 T-cell': '28.4', 'Central memory CD8 T-cell': '27.1', 'Effector memory CD8 T-cell': '31.7', 'Terminal effector memory CD8 T-cell': '27.7', 'Non-switched memory B-cell': '27.7', 'Plasmablast': '41.6', 'Switched memory B-cell': '22.8', 'Exhausted memory B-cell': '28.4', 'Progenitor cell': '47.3', 'Memory T-reg': '45.7', 'Naive CD4 T-cell activated': '19.0', 'Naive CD8 T-cell activated': '24.4', 'Naive T-reg': '28.1'}
2GF7, 2GFA, 2GP3, 2GP5, 2OQ6, 2OQ7, 2OS2, 2OT7, 2OX0, 2P5B, 2PXJ, 2Q8C, 2Q8D, 2Q8E, 2QQR, 2QQS, 2VD7, 2WWJ, 2YBK, 2YBP, 2YBS, 3NJY, 3PDQ, 3RVH, 3U4S, 4AI9, 4BIS, 4GD4, 4URA, 4V2V, 4V2W, 5A7N, 5A7O, 5A7P, 5A7Q, 5A7S, 5A7W, 5A80, 5ANQ, 5D6W, 5D6X, 5D6Y, 5F2S, 5F2W, 5F32, 5F37, 5F39, 5F3C, 5F3E, 5F3G, 5F3I, 5F5I, 5FPV, 5FWE, 5FY8, 5FYC, 5FYH, 5FYI, 5LY1, 5LY2, 5TVR, 5TVS, 5VAR, 5VGI, 5VMP, 6CG1, 6CG2, 6G5W, 6G5X, 6H4O, 6H4P, 6H4Q, 6H4R, 6H4S, 6H4T, 6H4U, 6H4V, 6H4W, 6H4X, 6H4Y, 6H8P, 6HGT, 7D4A, 7EQV, 8WD3
{'Adipose Tissue': 14.372023255813954, 'Adrenal Gland': 24.17133720930233, 'Bladder': 19.16409523809524, 'Blood': 9.748194402583422, 'Blood Vessel': 14.065113857677902, 'Brain': 10.738904125662378, 'Breast': 17.09700871459695, 'Cervix Uteri': 22.681578947368426, 'Colon': 15.167788189987164, 'Esophagus': 14.380433217993078, 'Fallopian Tube': 20.04111111111111, 'Heart': 5.161816957026714, 'Kidney': 8.719460674157304, 'Liver': 7.69579203539823, 'Lung': 16.826657439446365, 'Muscle': 7.088404732254046, 'Nerve': 19.023063004846527, 'Ovary': 24.13888888888889, 'Pancreas': 5.787734756097561, 'Pituitary': 16.73671731448763, 'Prostate': 17.8578612244898, 'Salivary Gland': 17.462827160493827, 'Skin': 26.26300221116639, 'Small Intestine': 16.880962566844918, 'Spleen': 17.90554356846473, 'Stomach': 11.89083844011142, 'Testis': 10.090393351800554, 'Thyroid': 20.960574272588055, 'Uterus': 23.64907042253521, 'Vagina': 19.454884615384618}
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0.11, 0.52, 0.24, 0.02, 0.58, 0.34, 0.0, 0.37, 0.49, 0.23, 0.46, 0.71, 0.79, 0.8, 0.88, 0.96, 0.93, 0.97, 0.97, 0.98, 0.97, 1.0, 1.0, 0.99, 0.99, 0.95, 0.98, 0.91, 1.0, 0.91, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 0.93, 1.0, 0.97, 1.0, 0.9, 0.94, 0.92, 0.85, 0.91, 0.87, 0.69, 0.87, 0.66, 0.76, 0.49, 0.54, 0.13, 0.66, 0.28, 0.31, 0.68, 0.47, 0.42, 0.75, 0.65, 0.9, 0.78, 0.98, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.81, 1.0, 0.73, 1.0, 1.0, 0.97, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 1.0, 0.97, 1.0, 0.97, 0.99, 0.99, 0.98, 1.0, 0.92, 0.96, 0.87, 0.94, 0.82, 0.97, 0.87, 0.73, 0.96, 0.71, 0.95, 0.86, 0.77, 0.87, 0.78, 0.95, 0.97, 0.91, 0.98, 0.93, 0.98, 0.94, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 0.99, 0.99, 0.98, 0.98, 1.0, 1.0, 0.98, 1.0, 0.96, 0.95, 0.94, 0.96, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.99, 1.0, 0.99, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.96, 1.0, 0.92, 1.0, 0.95, 1.0, 0.8, 1.0, 0.84, 1.0, 1.0, 1.0, 1.0, 0.97, 1.0, 0.97, 1.0, 0.98, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 0.98, 0.97, 0.9, 0.94, 0.72, 0.45, 0.83, 0.77, 0.39, 0.64, 0.5, 0.59, 0.64, 0.46, 0.6, 0.7, 0.66, 0.6, 0.6, 0.47, 0.55, 0.7, 0.73, 0.81, 0.85, 0.92, 1.0, 1.0, 0.99, 0.99, 1.0, 0.98, 1.0, 1.0, 1.0, 1.0, 0.97, 0.89, 0.98, 0.94, 0.67, 0.95, 0.82, 0.74, 0.99, 0.87, 0.94, 0.94, 0.87, 0.93, 0.9, 0.87, 0.97, 0.83, 0.87, 0.92, 0.86, 0.77, 0.51, 0.75, 0.78, 0.41, 0.73, 0.54, 0.29, 0.35, 0.84, 0.42, 0.73, 0.25, 0.05, 0.68, 0.71, 0.07, 0.19, 0.5, 0.02, 0.06, 0.21, 0.54, 0.42, 0.87, 0.62, 0.33, 0.22, 0.73, 0.15, 0.01, 0.36, 0.64, 0.21, 0.04, 0.4, 0.48, 0.15, 0.11, 0.75, 0.39, 0.64, 0.11, 0.24, 0.0, 0.21, 0.01, 0.0, 0.05, 0.05, 0.01, 0.16, 0.19, 0.19, 0.4, 0.58, 0.32, 0.62, 0.65, 0.53, 0.79, 0.73, 0.85, 0.62, 0.88, 0.68, 0.83, 0.88, 0.87, 0.88, 1.0, 0.98, 0.79, 0.94, 0.84, 0.64, 0.52, 0.48, 0.28, 0.61, 0.21, 0.17, 0.07, 0.37, 0.12, 0.4, 0.0, 0.02, 0.08, 0.14, 0.25, 0.66, 0.65, 0.55, 0.79, 0.93, 0.43, 0.81, 0.6, 0.65, 0.49, 0.18, 0.27, 0.34, 0.34, 1.0, 0.53, 0.37, 0.11, 0.0, 0.11, 0.13, 0.03, 0.35, 0.03, 0.63, 0.33, 0.08, 0.15, 0.03, 0.28, 0.0, 0.0, 0.02, 0.02, 0.01, 0.03, 0.15, 0.06, 0.32, 0.39, 0.95, 0.63, 0.09, 0.54, 0.85, 0.62, 0.11, 0.51, 0.04, 0.3, 0.06, 0.05, 0.56, 0.57, 0.61, 0.13, 0.28, 0.77, 0.45, 0.24, 0.04, 0.23, 0.0, 0.02, 0.01, 0.06, 0.08, 0.02, 0.18, 0.03, 0.04, 0.05, 0.48, 0.04, 0.51, 0.49, 0.59, 0.42, 0.05, 0.0, 0.06, 0.01, 0.15, 0.0, 0.01, 0.0, 0.07, 0.0, 0.22, 0.15, 0.02, 0.26, 0.06, 0.58, 0.38, 0.22, 0.28, 0.51, 0.0, 0.27, 0.39, 0.0, 0.07, 0.06, 0.75, 0.55, 0.07, 0.26, 0.71, 0.5, 0.11, 0.26, 0.78, 0.13, 0.52, 0.03, 0.42, 0.14, 0.06, 0.6, 0.76, 0.18, 0.19, 0.81, 0.86, 0.57, 0.52, 0.06, 0.0, 0.0, 0.04, 0.19, 0.0, 0.1, 0.31, 0.29, 0.75, 0.11, 0.67, 0.13, 0.05, 0.0, 0.03, 0.01, 0.17, 0.0, 0.0, 0.27, 0.29, 0.19, 0.25, 0.0, 0.12, 0.0, 0.29, 0.24, 0.19, 0.84, 0.57, 0.75, 0.21, 0.01, 0.09, 0.2, 0.02, 0.08, 0.02, 0.42, 0.86, 0.19, 0.34, 0.75, 0.84, 0.34, 0.73, 0.76, 0.81, 0.32, 0.63, 0.78, 0.69, 0.32, 0.48, 0.87, 0.06, 0.63, 0.56, 0.53, 0.27, 0.5, 0.0, 0.08, 0.0, 0.5, 0.17, 0.7, 0.56, 0.1, 0.56, 0.04, 0.24, 0.42, 0.04, 0.41, 0.01, 0.42, 0.59, 0.36, 0.24, 0.71, 0.25, 0.35, 0.04, 0.03, 0.25, 0.0, 0.49, 0.11, 0.6, 0.8, 0.85, 0.4, 0.71, 0.02, 0.5, 0.57, 0.03, 0.41, 0.1, 0.66, 0.22, 0.05, 0.35, 0.49, 0.33, 0.45, 0.06, 0.65, 0.86, 0.77, 0.27, 0.59, 0.09, 0.58, 0.8, 0.52, 0.42, 0.68, 0.03, 0.52, 0.0, 0.49, 0.37, 0.99, 0.39, 0.5, 0.46, 0.47, 0.4, 0.34, 0.0, 0.51, 0.05, 0.29, 0.24, 0.41, 0.36, 0.69, 0.26, 0.51, 0.07, 0.04, 0.15, 0.0, 0.38, 0.05, 0.73, 0.66, 0.54, 0.2, 0.4, 0.25, 0.45, 0.11, 0.36, 0.14, 0.48, 0.33, 0.0, 0.1, 0.01, 0.5, 0.84, 0.15, 0.86, 0.11, 0.36, 0.56, 0.51, 0.0, 0.49, 0.78, 0.52, 0.34, 0.25, 0.88, 0.58, 0.71, 0.91, 1.0, 0.95, 0.99, 0.98, 0.98, 0.97, 0.97, 1.0, 0.95, 0.98, 0.98, 0.93, 0.93, 0.93, 0.84, 0.95, 0.91, 0.75, 0.86, 0.51, 0.16, 0.33, 0.28, 0.27, 0.46, 0.39, 0.57, 0.55, 0.54, 0.41, 0.51, 0.6, 0.52, 0.54, 0.57, 0.51, 0.57, 0.66, 0.63, 0.71, 0.74]
RING finger
null
null
null
RXRA,MDC1,HERC2, PIWIL1, WRAP53
H2A,H2AX, H2B, PCNA,CHEK2, JMJD2A , KU80, POLD4
63, 48
null
UBE2N, UBE2E1, UBE2E2, UBE2E3, UBE2V2, UBE2L6
Homodimer
null
74.943402
0.531773
71.940498
0.481523
418
O76064
O76064
22199232, hUbiquitome
UbiNet, UbiBrowser, 31181401
RNF8
MGEPGFFVTGDRAGGRSWCLRRVGMSAGWLLLEDGCEVTVGRGFGVTYQLVSKICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLENKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDELAGPGAEGPSNLKSKINKVSCESGQPVKSQGKGEVASTPSDNLDPKLTALEPSKTTGAPIYPGFPKVTEVHHEQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKGNSKKVVQMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGLEIAQGEKDLKQQLAQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERKAKRLF
Homo sapiens
Nucleus, Cytoplasm, Midbody, Chromosome, telomere
Low tissue specificity
{'Ciliated cells': '32.7', 'Basal respiratory cells': '25.8', 'Club cells': '21.1', 'Ionocytes': '14.7', 'Mucus glandular cells': '22.1', 'Serous glandular cells': '22.6', 'Gastric mucus-secreting cells': '17.7', 'Proximal enterocytes': '10.5', 'Paneth cells': '15.1', 'Distal enterocytes': '10.0', 'Intestinal goblet cells': '16.0', 'Exocrine glandular cells': '-0.639', 'Basal prostatic cells': '20.0', 'Prostatic glandular cells': '17.9', 'Breast glandular cells': '0.548', 'Breast myoepithelial cells': '0.568', 'Glandular and luminal cells': '55.4', 'Secretory cells': '20.7', 'Basal keratinocytes': '26.6', 'Suprabasal keratinocytes': '36.6', 'Basal squamous epithelial cells': '26.4', 'Squamous epithelial cells': '35.6', 'Alveolar cells type 1': '0.317', 'Alveolar cells type 2': '-0.116', 'Salivary duct cells': '32.2', 'Ductal cells': '0.590', 'Hepatocytes': '0.475', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.086', 'Distal tubular cells': '24.6', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.464', 'Sertoli cells': '0.410', 'Granulosa cells': '33.8', 'Enteroendocrine cells': '22.9', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '0.234', 'Excitatory neurons': '16.4', 'Inhibitory neurons': '15.3', 'Cone photoreceptor cells': '23.8', 'Rod photoreceptor cells': '28.9', 'Bipolar cells': '24.0', 'Horizontal cells': '33.4', 'Astrocytes': '12.7', 'Oligodendrocyte precursor cells': '11.8', 'Oligodendrocytes': '19.1', 'Microglial cells': '10.7', 'Muller glia cells': '24.2', 'Schwann cells': '0.051', 'Spermatogonia': '0.378', 'Spermatocytes': '0.279', 'Early spermatids': '0.119', 'Late spermatids': '-0.231', 'Oocytes': '48.5', 'Cytotrophoblasts': '26.4', 'Syncytiotrophoblasts': '4.6', 'Extravillous trophoblasts': '26.8', 'Endothelial cells': '19.7', 'Lymphatic endothelial cells': '20.6', 'Cardiomyocytes': '0.619', 'Skeletal myocytes': '-0.121', 'Smooth muscle cells': '23.0', 'Adipocytes': '20.2', 'Melanocytes': '0.232', 'Fibroblasts': '24.9', 'Peritubular cells': '0.077', 'Endometrial stromal cells': '33.0', 'Ovarian stromal cells': '30.3', 'Undifferentiated cells': '21.0', 'T-cells': '18.9', 'B-cells': '16.3', 'Plasma cells': '14.9', 'Nk-cells': '29.2', 'Granulocytes': '26.0', 'Monocytes': '7.6', 'Macrophages': '12.8', 'Hofbauer cells': '17.3', 'Kupffer cells': '11.9', 'Dendritic cells': '2.4', 'Langerhans cells': '0.124', 'Erythroid cells': '-0.012', 'Adipocytes (Subcutaneous)': '-0.436', 'Adipocytes (Visceral)': '-0.390', 'Breast glandular cells (progenitors)': '0.348', 'Adipocytes (Breast)': '-0.563', 'Colon enterocytes': '-0.240', 'Colon enteroendocrine cells': '0.233', 'Enteric glia cells': '0.133', 'Mitotic cells (Colon)': '-0.099', 'Mitotic cells (Heart)': '0.484', 'Podocytes': '-0.044', 'Ascending Loop of Henle cells': '0.513', 'Intercalated cells': '-0.001', 'Cholangiocyte': '0.376', 'NK-cells (Liver)': '-0.277', 'Respiratory ciliated cells': '0.004', 'Mitotic cells (Lung)': '0.045', 'NK-cells (Lung)': '0.113', 'B-cells (Lung)': '-0.101', 'Alpha cells': '0.425', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '0.127', 'Urothelial cells': '0.140', 'Keratinocyte (other)': '0.153', 'Keratinocyte (granular)': '-0.072', 'Hair cortex cells': '0.151', 'Inner root sheath cells': '0.238', 'Outer root sheath cells': '0.191', 'Sebaceous gland cells': '-0.083', 'Eccrine sweat gland cells': '-0.018', 'Adipocytes (Skin)': '-0.127', 'Mitotic cells (Skin)': '0.363', 'Parietal cells': '-0.661', 'Chief cells': '-0.525', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.388', 'Mitotic cells (Stomach)': '0.107', 'Parafollicular cells': '0.052', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '0.048', 'Adrenal cortex cells': '0.419', 'Adrenal medulla cells': '-0.060', 'Mitotic cells (Adrenal gland)': '0.248', 'Minor salivary glandular cells': '0.280', 'Minor salivary gland ductal cells': '-0.198', 'Minor salivary gland basal cells': '0.681', 'Mitotic cells (Minor salivary gland)': '0.719', 'Adipocytes (Minor salivary gland)': '0.238', 'Somatotropes': '-0.119', 'Lactotropes': '-0.073', 'Gonadotropes': '-0.014', 'Corticotropes': '-0.061', 'Thyrotropes': '0.233', 'Undifferentiated cells (Pituitary gland)': '0.337', 'Mitotic cells (Spleen)': '-0.155', 'Platelets': '-0.175', 'Erythrocytes': '-0.025', 'Hematopoietic stem cells': '-0.189', 'B-cells (Spleen)': '0.376', 'NK-cells (Spleen)': '0.258', 'Amygdala excitatory': '29.0', 'Cerebellar inhibitory': '39.4', 'Cge interneuron': '30.6', 'Deep-layer corticothalamic and 6b': '32.4', 'Deep-layer intratelencephalic': '28.1', 'Deep-layer near-projecting': '24.6', 'Eccentric medium spiny neuron': '32.5', 'Hippocampal ca1-3': '25.5', 'Hippocampal ca4': '28.2', 'Hippocampal dentate gyrus': '28.6', 'Lamp5-lhx6 and chandelier': '37.6', 'Lower rhombic lip': '16.6', 'Mammillary body': '30.7', 'Medium spiny neuron': '28.0', 'Mge interneuron': '25.4', 'Midbrain-derived inhibitory': '31.2', 'Miscellaneous': '25.9', 'Splatter': '26.5', 'Thalamic excitatory': '31.9', 'Upper rhombic lip': '39.0', 'Upper-layer intratelencephalic': '31.1', 'Astrocyte': '27.4', 'Bergmann glia': '29.1', 'Central nervous system macrophage': '21.1', 'Choroid plexus epithelial cell': '30.8', 'Committed oligodendrocyte precursor': '23.7', 'Ependymal cell': '22.5', 'Oligodendrocyte': '35.3', 'Oligodendrocyte precursor cell': '24.5', 'Endothelial cell': '34.2', 'Pericyte': '18.1', 'Vascular associated smooth muscle cell': '19.0', 'Fibroblast': '21.5', 'Leukocyte': '23.3', 'Basophil': '1.5', 'Eosinophil': '2.5', 'Neutrophil': '1.5', 'Classical monocyte': '3.7', 'Non-classical monocyte': '5.5', 'Intermediate monocyte': '8.2', 'T-reg': '7.3', 'GdT-cell': '9.5', 'MAIT T-cell': '7.7', 'Memory CD4 T-cell': '7.0', 'Naive CD4 T-cell': '10.8', 'Memory CD8 T-cell': '9.1', 'Naive CD8 T-cell': '8.8', 'Memory B-cell': '8.1', 'Naive B-cell': '6.3', 'Plasmacytoid DC': '3.8', 'Myeloid DC': '6.4', 'NK-cell': '13.1', 'Total PBMC': '9.1', 'Vd2 gdTCR': '11.1', 'Memory CD4 T-cell Th1\\/Th17': '10.8', 'Memory CD4 T-cell Th17': '10.8', 'Memory CD4 T-cell Th2': '9.7', 'Non-Vd2 gdTCR': '10.4', 'Memory CD4 T-cell Th1': '10.4', 'Memory CD4 T-cell TFH': '10.4', 'Terminal effector memory CD4 T-cell': '6.4', 'Central memory CD8 T-cell': '7.0', 'Effector memory CD8 T-cell': '8.2', 'Terminal effector memory CD8 T-cell': '10.0', 'Non-switched memory B-cell': '9.8', 'Plasmablast': '10.4', 'Switched memory B-cell': '6.9', 'Exhausted memory B-cell': '7.2', 'Progenitor cell': '9.2', 'Memory T-reg': '10.2', 'Naive CD4 T-cell activated': '6.2', 'Naive CD8 T-cell activated': '8.5', 'Naive T-reg': '10.5'}
2CSW, 2PIE, 4AYC, 4ORH, 4WHV
{'Adipose Tissue': 5.842281561461794, 'Adrenal Gland': 7.026077519379845, 'Bladder': 7.759809523809524, 'Blood': 3.220500215285253, 'Blood Vessel': 8.356130337078651, 'Brain': 7.779572937168812, 'Breast': 6.3104291938997825, 'Cervix Uteri': 9.987631578947369, 'Colon': 6.505412066752247, 'Esophagus': 8.088813840830449, 'Fallopian Tube': 9.497888888888887, 'Heart': 4.124628919860627, 'Kidney': 4.606573033707865, 'Liver': 2.3945101769911505, 'Lung': 7.91575259515571, 'Muscle': 4.271328767123288, 'Nerve': 8.343988691437803, 'Ovary': 10.546722222222222, 'Pancreas': 2.164347865853659, 'Pituitary': 8.595367491166078, 'Prostate': 8.065632653061224, 'Salivary Gland': 6.157123456790123, 'Skin': 8.770229961304588, 'Small Intestine': 5.831320855614974, 'Spleen': 5.645, 'Stomach': 4.767988857938719, 'Testis': 19.702216066481995, 'Thyroid': 6.970906584992344, 'Uterus': 10.236056338028169, 'Vagina': 10.048794871794872}
RNF8
MGEPGFFVTGDRAGGRSWCLRRVGMSAGWLLLEDGCEVTVGRGFGVTYQLVSKICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLENKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKELRTKRKFSLDELAGPGAEGPSNLKSKINKVSCESGQPVKSQGKGEVASTPSDNLDPKLTALEPSKTTGAPIYPGFPKVTEVHHEQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKHEAVMNVKKQTQKGNSKKVVQMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGLEIAQGEKDLKQQLAQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRERKAKRLF
Homo sapiens
Nucleus, Cytoplasm, Midbody, Chromosome, telomere
Low tissue specificity
{'Ciliated cells': '32.7', 'Basal respiratory cells': '25.8', 'Club cells': '21.1', 'Ionocytes': '14.7', 'Mucus glandular cells': '22.1', 'Serous glandular cells': '22.6', 'Gastric mucus-secreting cells': '17.7', 'Proximal enterocytes': '10.5', 'Paneth cells': '15.1', 'Distal enterocytes': '10.0', 'Intestinal goblet cells': '16.0', 'Exocrine glandular cells': '-0.639', 'Basal prostatic cells': '20.0', 'Prostatic glandular cells': '17.9', 'Breast glandular cells': '0.548', 'Breast myoepithelial cells': '0.568', 'Glandular and luminal cells': '55.4', 'Secretory cells': '20.7', 'Basal keratinocytes': '26.6', 'Suprabasal keratinocytes': '36.6', 'Basal squamous epithelial cells': '26.4', 'Squamous epithelial cells': '35.6', 'Alveolar cells type 1': '0.317', 'Alveolar cells type 2': '-0.116', 'Salivary duct cells': '32.2', 'Ductal cells': '0.590', 'Hepatocytes': '0.475', 'Cholangiocytes': '15.3', 'Proximal tubular cells': '0.086', 'Distal tubular cells': '24.6', 'Collecting duct cells': '23.3', 'Mesothelial cells': '0.464', 'Sertoli cells': '0.410', 'Granulosa cells': '33.8', 'Enteroendocrine cells': '22.9', 'Pancreatic endocrine cells': '17.0', 'Leydig cells': '0.234', 'Excitatory neurons': '16.4', 'Inhibitory neurons': '15.3', 'Cone photoreceptor cells': '23.8', 'Rod photoreceptor cells': '28.9', 'Bipolar cells': '24.0', 'Horizontal cells': '33.4', 'Astrocytes': '12.7', 'Oligodendrocyte precursor cells': '11.8', 'Oligodendrocytes': '19.1', 'Microglial cells': '10.7', 'Muller glia cells': '24.2', 'Schwann cells': '0.051', 'Spermatogonia': '0.378', 'Spermatocytes': '0.279', 'Early spermatids': '0.119', 'Late spermatids': '-0.231', 'Oocytes': '48.5', 'Cytotrophoblasts': '26.4', 'Syncytiotrophoblasts': '4.6', 'Extravillous trophoblasts': '26.8', 'Endothelial cells': '19.7', 'Lymphatic endothelial cells': '20.6', 'Cardiomyocytes': '0.619', 'Skeletal myocytes': '-0.121', 'Smooth muscle cells': '23.0', 'Adipocytes': '20.2', 'Melanocytes': '0.232', 'Fibroblasts': '24.9', 'Peritubular cells': '0.077', 'Endometrial stromal cells': '33.0', 'Ovarian stromal cells': '30.3', 'Undifferentiated cells': '21.0', 'T-cells': '18.9', 'B-cells': '16.3', 'Plasma cells': '14.9', 'Nk-cells': '29.2', 'Granulocytes': '26.0', 'Monocytes': '7.6', 'Macrophages': '12.8', 'Hofbauer cells': '17.3', 'Kupffer cells': '11.9', 'Dendritic cells': '2.4', 'Langerhans cells': '0.124', 'Erythroid cells': '-0.012', 'Adipocytes (Subcutaneous)': '-0.436', 'Adipocytes (Visceral)': '-0.390', 'Breast glandular cells (progenitors)': '0.348', 'Adipocytes (Breast)': '-0.563', 'Colon enterocytes': '-0.240', 'Colon enteroendocrine cells': '0.233', 'Enteric glia cells': '0.133', 'Mitotic cells (Colon)': '-0.099', 'Mitotic cells (Heart)': '0.484', 'Podocytes': '-0.044', 'Ascending Loop of Henle cells': '0.513', 'Intercalated cells': '-0.001', 'Cholangiocyte': '0.376', 'NK-cells (Liver)': '-0.277', 'Respiratory ciliated cells': '0.004', 'Mitotic cells (Lung)': '0.045', 'NK-cells (Lung)': '0.113', 'B-cells (Lung)': '-0.101', 'Alpha cells': '0.425', 'Beta cells': '0.257', 'Prostate glandular cells': '-0.279', 'Prostate basal glandular cells': '0.127', 'Urothelial cells': '0.140', 'Keratinocyte (other)': '0.153', 'Keratinocyte (granular)': '-0.072', 'Hair cortex cells': '0.151', 'Inner root sheath cells': '0.238', 'Outer root sheath cells': '0.191', 'Sebaceous gland cells': '-0.083', 'Eccrine sweat gland cells': '-0.018', 'Adipocytes (Skin)': '-0.127', 'Mitotic cells (Skin)': '0.363', 'Parietal cells': '-0.661', 'Chief cells': '-0.525', 'Gastric mucous cells': '-0.366', 'Gastric enteroendocrine cells': '-0.388', 'Mitotic cells (Stomach)': '0.107', 'Parafollicular cells': '0.052', 'Thyroid glandular cells': '0.320', 'Mitotic cells (Thyroid)': '0.048', 'Adrenal cortex cells': '0.419', 'Adrenal medulla cells': '-0.060', 'Mitotic cells (Adrenal gland)': '0.248', 'Minor salivary glandular cells': '0.280', 'Minor salivary gland ductal cells': '-0.198', 'Minor salivary gland basal cells': '0.681', 'Mitotic cells (Minor salivary gland)': '0.719', 'Adipocytes (Minor salivary gland)': '0.238', 'Somatotropes': '-0.119', 'Lactotropes': '-0.073', 'Gonadotropes': '-0.014', 'Corticotropes': '-0.061', 'Thyrotropes': '0.233', 'Undifferentiated cells (Pituitary gland)': '0.337', 'Mitotic cells (Spleen)': '-0.155', 'Platelets': '-0.175', 'Erythrocytes': '-0.025', 'Hematopoietic stem cells': '-0.189', 'B-cells (Spleen)': '0.376', 'NK-cells (Spleen)': '0.258', 'Amygdala excitatory': '29.0', 'Cerebellar inhibitory': '39.4', 'Cge interneuron': '30.6', 'Deep-layer corticothalamic and 6b': '32.4', 'Deep-layer intratelencephalic': '28.1', 'Deep-layer near-projecting': '24.6', 'Eccentric medium spiny neuron': '32.5', 'Hippocampal ca1-3': '25.5', 'Hippocampal ca4': '28.2', 'Hippocampal dentate gyrus': '28.6', 'Lamp5-lhx6 and chandelier': '37.6', 'Lower rhombic lip': '16.6', 'Mammillary body': '30.7', 'Medium spiny neuron': '28.0', 'Mge interneuron': '25.4', 'Midbrain-derived inhibitory': '31.2', 'Miscellaneous': '25.9', 'Splatter': '26.5', 'Thalamic excitatory': '31.9', 'Upper rhombic lip': '39.0', 'Upper-layer intratelencephalic': '31.1', 'Astrocyte': '27.4', 'Bergmann glia': '29.1', 'Central nervous system macrophage': '21.1', 'Choroid plexus epithelial cell': '30.8', 'Committed oligodendrocyte precursor': '23.7', 'Ependymal cell': '22.5', 'Oligodendrocyte': '35.3', 'Oligodendrocyte precursor cell': '24.5', 'Endothelial cell': '34.2', 'Pericyte': '18.1', 'Vascular associated smooth muscle cell': '19.0', 'Fibroblast': '21.5', 'Leukocyte': '23.3', 'Basophil': '1.5', 'Eosinophil': '2.5', 'Neutrophil': '1.5', 'Classical monocyte': '3.7', 'Non-classical monocyte': '5.5', 'Intermediate monocyte': '8.2', 'T-reg': '7.3', 'GdT-cell': '9.5', 'MAIT T-cell': '7.7', 'Memory CD4 T-cell': '7.0', 'Naive CD4 T-cell': '10.8', 'Memory CD8 T-cell': '9.1', 'Naive CD8 T-cell': '8.8', 'Memory B-cell': '8.1', 'Naive B-cell': '6.3', 'Plasmacytoid DC': '3.8', 'Myeloid DC': '6.4', 'NK-cell': '13.1', 'Total PBMC': '9.1', 'Vd2 gdTCR': '11.1', 'Memory CD4 T-cell Th1\\/Th17': '10.8', 'Memory CD4 T-cell Th17': '10.8', 'Memory CD4 T-cell Th2': '9.7', 'Non-Vd2 gdTCR': '10.4', 'Memory CD4 T-cell Th1': '10.4', 'Memory CD4 T-cell TFH': '10.4', 'Terminal effector memory CD4 T-cell': '6.4', 'Central memory CD8 T-cell': '7.0', 'Effector memory CD8 T-cell': '8.2', 'Terminal effector memory CD8 T-cell': '10.0', 'Non-switched memory B-cell': '9.8', 'Plasmablast': '10.4', 'Switched memory B-cell': '6.9', 'Exhausted memory B-cell': '7.2', 'Progenitor cell': '9.2', 'Memory T-reg': '10.2', 'Naive CD4 T-cell activated': '6.2', 'Naive CD8 T-cell activated': '8.5', 'Naive T-reg': '10.5'}
2CSW, 2PIE, 4AYC, 4ORH, 4WHV
{'Adipose Tissue': 5.842281561461794, 'Adrenal Gland': 7.026077519379845, 'Bladder': 7.759809523809524, 'Blood': 3.220500215285253, 'Blood Vessel': 8.356130337078651, 'Brain': 7.779572937168812, 'Breast': 6.3104291938997825, 'Cervix Uteri': 9.987631578947369, 'Colon': 6.505412066752247, 'Esophagus': 8.088813840830449, 'Fallopian Tube': 9.497888888888887, 'Heart': 4.124628919860627, 'Kidney': 4.606573033707865, 'Liver': 2.3945101769911505, 'Lung': 7.91575259515571, 'Muscle': 4.271328767123288, 'Nerve': 8.343988691437803, 'Ovary': 10.546722222222222, 'Pancreas': 2.164347865853659, 'Pituitary': 8.595367491166078, 'Prostate': 8.065632653061224, 'Salivary Gland': 6.157123456790123, 'Skin': 8.770229961304588, 'Small Intestine': 5.831320855614974, 'Spleen': 5.645, 'Stomach': 4.767988857938719, 'Testis': 19.702216066481995, 'Thyroid': 6.970906584992344, 'Uterus': 10.236056338028169, 'Vagina': 10.048794871794872}
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RING finger
null
null
null
RXRA,MDC1,HERC2, PIWIL1, WRAP53
H2A,H2AX, H2B, PCNA,CHEK2, JMJD2A , KU80, POLD4
63, 48
null
UBE2N, UBE2E1, UBE2E2, UBE2E3, UBE2V2, UBE2L6
Homodimer
null
74.943402
0.531773
74.943402
0.531773
1,639