title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Genotype-correlated expression of lysyl oxidase-like 1 in ocular tissues of patients with pseudoexfoliation syndrome/glaucoma and normal patients. | Pseudoexfoliation (PEX) syndrome is a generalized disease of the extracellular matrix and the most common identifiable cause of open-angle glaucoma. Two single nucleotide polymorphisms in the lysyl oxidase-like 1 (LOXL1) gene (rs1048661 and rs3825942) have been recently identified as strong genetic risk factors for bot... | 18,974,306 |
Bat white-nose syndrome: an emerging fungal pathogen? | White-nose syndrome (WNS) is a condition associated with an unprecedented bat mortality event in the northeastern United States. Since the winter of 2006*2007, bat declines exceeding 75% have been observed at surveyed hibernacula. Affected bats often present with visually striking white fungal growth on their muzzles, ... | 18,974,316 |
Structural insights into a circadian oscillator. | An endogenous circadian system in cyanobacteria exerts pervasive control over cellular processes, including global gene expression. Indeed, the entire chromosome undergoes daily cycles of topological changes and compaction. The biochemical machinery underlying a circadian oscillator can be reconstituted in vitro with j... | 18,974,343 |
Presence of donor-derived DNA and cells in the urine of sex-mismatched hematopoietic stem cell transplant recipients: implication for the transrenal hypothesis. | The term "transrenal DNA" was coined in 2000 to signify that DNA in urine may come from the passage of plasma DNA through the kidney barrier. Although DNA in the urine has the potential to provide a completely noninvasive source of nucleic acids for molecular diagnosis, its existence remains controversial. We obtained ... | 18,974,360 |
The physiology and pathophysiology of human breath-hold diving. | This is a brief overview of physiological reactions, limitations, and pathophysiological mechanisms associated with human breath-hold diving. Breath-hold duration and ability to withstand compression at depth are the two main challenges that have been overcome to an amazing degree as evidenced by the current world reco... | 18,974,367 |
Lithium upregulates vascular endothelial growth factor in brain endothelial cells and astrocytes. | We recently reported that delayed lithium therapy can improve stroke recovery in rats by augmenting neurovascular remodeling. We tested the hypothesis that lithium can promote the expression of growth factors in brain endothelial cells and astrocytes. Human brain microvascular endothelial cells and primary rat cortical... | 18,974,377 |
Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis. | Therapeutic angiogenesis using autologous stem/progenitor cells represents a novel strategy for severe ischemic diseases. Recent reports indicated that adipose tissues could supply adipose-derived regenerative cells (ADRCs). Accordingly, we examined whether implantation of ADRCs would augment ischemia-induced angiogene... | 18,974,384 |
Determination of aortic valve opening time and left ventricular peak filling rate from the peripheral pulse amplitude in patients with ectopic beats. | Ectopic beats are common in patients who have heart disease and are associated with reduced peripheral pulse amplitude. This study determined the start of the peripheral pulse increase and from it the opening of the aortic valve. The left ventricular peak filling rate was also estimated from the peripheral pulse. Resul... | 18,974,441 |
[Osteoarthritis of the knee joint as a cause of musculoskeletal ambulation disability symptom complex (MADS)]. | Osteoarthritis is considered as a chronic disease of the whole joint, including articular cartilage, meniscus, ligament, and peri-articular muscle that may result from multiple pathophysiological mechanisms. Osteoarthritis is a painful and disabling disease that affects millions of patients. Its aetiology is largely un... | 18,974,445 |
[Dynamic flamingo therapy]. | A long follow up study of one minute unipedal standing therapy 3 times in a day to prevent femoral neck osteoporosis that have started from 1993 was reported. The registration from July 1993 to March 2004 were 86 cases which measured the femoral neck bone mineral density (BMD) according to dual energy x-ray absorptiome... | 18,974,448 |
Risk of venous thrombosis in patients with hepatic malignancies undergoing surgical resection. | The risk of venous thrombosis is well documented in patients with malignancies, those undergoing abdominal surgery, and those undergoing hepatic resection for malignancy. This study was undertaken to determine whether there was a difference in the risk of thrombosis between those undergoing resection for hepatic metast... | 18,974,467 |
Bio-aerosols in indoor environment: composition, health effects and analysis. | Bio-aerosols are airborne particles that are living (bacteria, viruses and fungi) or originate from living organisms. Their presence in air is the result of dispersal from a site of colonization or growth. The health effects of bio-aerosols including infectious diseases, acute toxic effects, allergies and cancer couple... | 18,974,481 |
High rate of mutation K103N causing resistance to nevirapine in Indian children with acquired immunodeficiency syndrome. | In north India the number of paediatric cases with acquired immunodeficiency syndrome (AIDS) is on the rise. Most drug combinations used for treatment of AIDS incorporate nevirapine, resistance to which develops very fast if given singly or because of unplanned interruptions. This paper investigates presence of mutatio... | 18,974,494 |
Fatal rhino-orbito-cerebral infection caused by Saksenaea vasiformis in an immunocompetent individual: first case report from India. | A 56-year-old female patient presented with history of nasal blockage, nasal bleeding, headache, since one month. On admission the patient developed severe headache, decreased vision of eyes and blindness. Clinical diagnosis of rhino-orbital involvement was confirmed by computerized tomography of the paranasal sinuses.... | 18,974,499 |
Clinical and histopathological features of posttraumatic iris cyst. | Iris cyst excision involves complex surgical maneuvers and may have a variable visual outcome depending upon preexisting and postoperative complications. Hereby, we report a case series of 10 eyes from which posttraumatic iris cysts were excised and proven histopathologically. Histopathology records were reviewed. Data... | 18,974,530 |
Lesch-Nyhan syndrome: a case report. | Lesch-Nyhan syndrome, a rare inborn error of metabolism, is characterized by mental retardation and self-destructive behavior resulting in self-mutilation through biting and scratching. It is a rare anomaly consisting of deficiency in the production of hypoxanthine phosphoribosyltransferase that leads to the overproduc... | 18,974,538 |
Interpretation of electroneuromyographic studies in diseases of neuromuscular junction and myopathies. | Electroneuromyography (ENMG) also called electrodiagnosis or at times simply (and erroneously) electromyography (EMG), has been used for the diagnosis of neuromuscular and muscle diseases. It consists of tests done serially and assessed collectively, to arrive at a diagnosis of neuromuscular weakness. The test should b... | 18,974,561 |
Deletion analysis of spinal muscular atrophy in southern Indian population. | Proximal spinal muscular atrophy (SMA) is a genetically heterogeneous disease with paresis and muscle atrophy due to loss of anterior horn cell function. The survival of motor neuron gene (SMN) and neuronal apoptosis inhibitory protein (NAIP) play a primary role. Both the gene homologues exist as inverted duplications ... | 18,974,562 |
Lipid storage myopathies with unusual clinical manifestations. | We describe the clinical presentation, course and pathologic findings found in three adult patients with lipid storage myopathy. Excessive lipid storage was found in Type 1 fibers of muscle. Clinical improvement on oral levo-carnitine therapy suggests the possibility of carnitine deficiency as the most likely etiology ... | 18,974,571 |
Twenty-two year follow-up of an Indian family with dysferlinopathy-clinical, immunocytochemical, western blotting and genetic features. | Long-term observations over a period of 22 years in an Indian family with primary dysferlinopathy are recorded, defining phenotypic variability. In the propositus, the dystrophy began distally in the tibialis anterior muscles, before involving the gastrocnemius. Transient painful calf hypertrophy, followed by calf wast... | 18,974,570 |
Wasp sting: an unusual fatal outcome. | Wasp stings are not uncommon especially in populations living in proximity of forested areas all over the world. Local manifestations following stings are common and un-usually life threatening anaphylaxis may occur, requiring prompt treatment. Multi organ failure and acute renal failure following wasp stings are rare ... | 18,974,586 |
Hypertension care at primary health care centers: a report from Abha, Saudi Arabia. | It is well known that effective management of hypertension reduces the incidence of myo-cardial infarction, stroke and vascular complications. The Ministry of Health, Kingdom of Saudi Arabia, introduced the Quality Assurance Guidelines with the hope to improve the management of hypertension in its centers. We conducted... | 18,974,594 |
Clinical and immunological manifestations of systemic lupus erythematosus: study on 146 south Tunisian patients. | The objective of this study was to determine the main clinical and laboratory features as well as the morbidity and mortality of systemic lupus erythematosus (SLE) in a population of patients predominantly from the south of Tunisia. A retrospective review of a well documented population of 146 patients with SLE was und... | 18,974,596 |
Chelatable Fe (II) is generated in the rat kidneys exposed to ischemia and reperfusion, and a divalent metal chelator, 2, 2'-dipyridyl, attenuates the acute ischemia/reperfusion-injury of the kidneys: a histochemical study by the perfusion-Perls and -Turnbull methods. | The perfusion-Perls and -Turnbull methods supplemented by diaminobenzidine intensification demonstrated the generation and localization of chelatable Fe (II) which can catalyze the generation of cytotoxic hydroxyl radicals (OH.) during the Fenton reaction in rat kidneys exposed to 40 min ischemia or 40 min-ischemia fol... | 18,974,602 |
Assessment of ileal epithelial P-glycoprotein dysfunction induced by ischemia/reperfusion using in vivo animal model. | We presented the ischemia/reperfusion (I/R) model which can evaluate changes in P-glycoprotein (P-gp) function induced by lipid peroxidation using surgical-sutures connected with the spring balance. The superior mesenteric artery and vein was occluded by hanging itself using surgical-sutures connected with the spring b... | 18,974,613 |
[MucoRice: development of rice-based oral vaccine]. | Parenteral vaccines are used commonly against most of infectious diseases. It is noted that these injection type vaccines are meant to induce protective immunity in the systemic compartment but not aimed at use of the benefits of mucosal immunity as a first line of defense against mucosal infectious diseases such as AI... | 18,974,620 |
[Immunotherapy using IL-6 receptor as the target]. | Monoclonal antibody-based therapy targeting interleukine-6 (IL-6) has been established as a treatment for autoimmune diseases, chronic inflammatory diseases, and lymphoproliferative disease. IL-6 is a multifunctional cytokine which plays pathological roles in Castleman's disease, rheumatoid arthritis, juvenile idiopath... | 18,974,624 |
Somatostatin receptor subtypes 2 and 5 are associated with better survival in well-differentiated endocrine carcinomas. | The majority of gastroenteropancreatic well-differentiated endocrine carcinomas (WDEC) express somatostatin receptors (SSTR). To correlate the expression of SSTR subtypes by reverse transcriptase-polymerase chain reaction (RT-PCR) with clinicopathological features and survival in a group of WDEC patients, 42 WDEC tissu... | 18,974,627 |
Vibration response imaging in the detection of pleural effusions: a feasibility study. | Computerized analysis of the regional distribution of breath sound intensity during respiration has generated interest as a possible diagnostic modality. We hypothesized that pleural effusions would create a dependent region of absent breath sounds and thus vibration response imaging (VRI) could be used in the detectio... | 18,974,633 |
How to best define patients with moderate chronic kidney disease. | The objective of this study was to identify which formula may best identify moderate chronic kidney disease (CKD) (glomerular filtration rate (GFR) cut-off of 60 ml/min/1.73 m(2)). We compared the performances of 14 serum creatinine (S(cr)) and 11 cystatin C (Cys C) estimated GFR equations using inulin clearance (Cl(in... | 18,974,650 |
The impact of prior multidisciplinary predialysis care on mineral metabolic control among chronic hemodialysis patients. | Disordered mineral metabolism is independently associated with mortality among chronic dialysis patients. We hypothesized that, upon dialysis start, biochemical markers of mineral metabolism would be better controlled among patients who had received multidisciplinary predialysis care (MDC). We conducted a retrospective... | 18,974,654 |
Building public support for anti-obesity policy initiatives. | Solving the obesity crisis has less to do with post-partisanship and more to do with increasing public support for strong public policy initiatives that will make the healthy choice the easy choice. The government has an important role in mitigating the toxic food environment created by food manufacturers and restauran... | 18,974,667 |
Psychiatric distress among Asian and European American survivors of the 1994 Northridge earthquake. | Relatively few studies focus on the psychological effects of trauma exposure on Asian Americans. This article presents secondary analyses of a random survey of 118 Asian American and 762 European American survivors of the 1994 Northridge, California earthquake. Asian American participants reported more psychiatric dist... | 18,974,671 |
Mixed-sex wards and patient dignity: nurses and patients perspectives. | With the exception of specialized units, adults have historically been cared for in single-sex hospital wards in the UK. However, over the past two decades, concerns about mixed-sex wards have been reported. Respect and dignity are essential to provide high-quality health care. The issue of whether patients' privacy an... | 18,974,690 |
The problems of alcohol and cigarette abuse: BJN 100 years ago. | The causation of inebriety or drunkenness was thought to be caused by two factors, according to Dr Harry Campbell (a former president of the Society for the Study of Inebriety): low resistance power to the allurement of alcohol and abundant access to alcoholic liquors. | 18,974,692 |
Molecular profiling of heparinase-I resistant glycosaminoglycans in contaminated heparins. Comparative studies with uncontaminated heparin and porcine oversulfated chondroitin sulfate. | Heparin is a widely used anticoagulant which is usually obtained from porcine mucosal tissue. The structure of heparin is comparable to other naturally occurring glycosaminoglycans such as chondroitin sulfate and dermatan sulfate. The commercially available heparin preparations may contain small amounts of dermatan sul... | 18,974,698 |
Specific inspiratory muscle training does not improve performance or VO2max levels in well trained rowers. | The purpose of this study was to examine the effects of specific inspiratory muscle training (IMT) on inspiratory muscle strength, maximal oxygen uptake (VO2max), maximal lactate accumulation (Lmax), dyspnea sensation and rowing performance in rowers. Ninteen well-trained rowers were divided into two groups: IMT (T) an... | 18,974,712 |
Tracking of adult adiposity in early, average and late maturing children: a thirty year longitudinal growth study. | To investigate if predictability of adult adiposity is related to maturation status in youth. Data of the longitudinal ''LEGS''-study (N = 550) from 6 to 18 years were used. At 35 years, 59 men and 60 women participated again. Early (EM), average (AM) and late (LM) maturity groups were established, using tertiles of ag... | 18,974,718 |
The effect of regular long term training on antioxidant enzymatic activities. | It has been reported that exercise induces oxidative stress and causes adaptations in antioxidant defenses. The purpose of the present study was to investigate the effects of regular long term training on antioxidant enzymatic activities consisting of superoxide dismutase (SOD), glutathion peroxidase (GPX) and glutathi... | 18,974,727 |
Calcimimetics, parathyroid hormone, and vascular calcification in chronic kidney disease. | Vascular calcification (VC) occurs frequently in chronic kidney disease, contributing to cardiovascular mortality. Numerous risk factors have been identified, including renal osteodystrophy and bone turnover, with low turnover as a main determinant. Other reports support high turnover as a factor in VC. Calcimimetics, ... | 18,974,757 |
Interactions between HIV-1 reverse transcriptase and the downstream template strand in stable complexes with primer-template. | Human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) forms stable ternary complexes in which RT is bound tightly at fixed positions on the primer-template (P/T). We have probed downstream interactions between RT and the template strand in the complex containing the incoming dNTP (+1 dNTP*RT*P/T complex)... | 18,974,785 |
A new method for forensic DNA analysis of the blood meal in chagas disease vectors demonstrated using Triatoma infestans from Chuquisaca, Bolivia. | Feeding patterns of the vector are important in the epidemiology of Chagas disease, the leading cause of heart disease in Latin America. Chagas disease is caused by the parasite, Trypanasoma cruzi, which is transmitted by blood feeding insects. Historically, feeding behaviours of haematophagous insects have been invest... | 18,974,787 |
A formal ontology of subcellular neuroanatomy. | The complexity of the nervous system requires high-resolution microscopy to resolve the detailed 3D structure of nerve cells and supracellular domains. The analysis of such imaging data to extract cellular surfaces and cell components often requires the combination of expert human knowledge with carefully engineered so... | 18,974,798 |
Library roles in disaster response: an oral history project by the National Library of Medicine. | To develop a knowledgebase of stories illustrating the variety of roles that librarians can assume in emergency and disaster planning, preparedness, response, and recovery, the National Library of Medicine conducted an oral history project during the summer of 2007. The history aimed to describe clearly and compellingl... | 18,974,811 |
Cell groups reveal structure of stimulus space. | An important task of the brain is to represent the outside world. It is unclear how the brain may do this, however, as it can only rely on neural responses and has no independent access to external stimuli in order to "decode" what those responses mean. We investigate what can be learned about a space of stimuli using ... | 18,974,826 |
Mosaic convergence of rodent dentitions. | Understanding mechanisms responsible for changes in tooth morphology in the course of evolution is an area of investigation common to both paleontology and developmental biology. Detailed analyses of molar tooth crown shape have shown frequent homoplasia in mammalian evolution, which requires accurate investigation of ... | 18,974,837 |
Identification of novel single nucleotide polymorphisms in inflammatory genes as risk factors associated with trachomatous trichiasis. | Trachoma is the leading preventable cause of global blindness. A balanced Th1/Th2/Th3 immune response is critical for resolving Chlamydia trachomatis infection, the primary cause of trachoma. Despite control programs that include mass antibiotic treatment, reinfection and recurrence of trachoma are common after treatme... | 18,974,840 |
All-optical anatomical co-registration for molecular imaging of small animals using dynamic contrast. | Optical molecular imaging in small animals harnesses the power of highly specific and biocompatible contrast agents for drug development and disease research1-7. However, the widespread adoption of in vivo optical imaging has been inhibited by its inability to clearly resolve and identify targeted internal organs. Opti... | 18,974,848 |
The treatment of condylar fractures: to open or not to open? A critical review of this controversy. | The treatment of condylar process fractures has generated a great deal of discussion and controversy in oral and maxillofacial trauma and there are many different methods to treat this injury. For each type of condylar fracture, the techniques must be chosen taking into consideration the presence of teeth, fracture hei... | 18,974,859 |
10th Anniversary Focus: an overview of trends related to tropical rainforest depletion and climate change. | Public awareness about the problems related to rainforest depletion increased considerably in the 1990s, but the level of emphasis to the problems faced by the world's tropical rainforests has become conspicuously low in recent years. Yet, there is a heightened sense of urgency in respect of the need to handle the chal... | 18,974,894 |
Assaying baseline status of particulate laden polyaromatic hydrocarbon for a grass root level industrial project. | A study of particulate laden polyaromatic hydrocarbon was conducted at 13 selected locations in a 10 km radial distance of a proposed site for a grass root level industry. Suspended particulate matter samples were continuously monitored for 24 h over a period of 3 months. The Polyaromatic Hydrocarbons (PAHs) were extra... | 18,974,916 |
Remaining lifetime and absolute 10-year probabilities of osteoporotic fracture in Swiss men and women. | Remaining lifetime and absolute 10-year probabilities for osteoporotic fractures were determined by gender, age, and BMD values. Remaining lifetime probability at age 50 years was 20.2% in men and 51.3% in women and increased with advancing age and decreasing BMD. The study validates the elements required to populate a... | 18,974,918 |
Emergence of SCCmec type IV as the most common type of methicillin-resistant Staphylococcus aureus in a university hospital. | The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) has dramatically changed over the last decade by the emergence of community-associated MRSA (CA-MRSA). Recent studies indicate that these strains have already spread to hospitals. To evaluate if SCCmec type IV and Panton-Valentine leukocidin (PVL) a... | 18,974,930 |
Molecular cloning and characterization of a single-chain variable fragment antibody specific for benzoylecgonine expressed in Escherichia coli. | Benzoylecgonine is a major metabolite of cocaine. We generated hybridoma cells (C1303) producing anti-benzoylecgonine monoclonal antibody (mAb) with a single-chain variable fragment (scFv) and an antigen-binding domain from the C1303 cells. Genes encoding an scFv antibody and constant region (Fc) were amplified from a ... | 18,974,960 |
Does stress shielding occur with the use of long-stem prosthesis in total knee arthroplasty? | A retrospective study conducted to evaluate the possible occurrence of stress shielding with the use of long-stem tibial prosthesis in total knee arthroplasty. Forty-one patients were reviewed (twenty-three standard prosthesis, eighteen long-stem prosthesis) and forty-one unoperated knee of the contralateral limb). Pat... | 18,974,974 |
Suitability of muscarinic acetylcholine receptor antibodies for immunohistochemistry evaluated on tissue sections of receptor gene-deficient mice. | Acetylcholine (ACh) is a major regulator of visceral function exerting pharmacologically relevant effects upon smooth muscle tone and epithelial function via five types of muscarinic receptors (M1R-M5R). In this paper, we assessed the specificity of muscarinic receptor (MR) antibodies in immunohistochemical labelling o... | 18,974,978 |
Constitutive expression of bergaptol O-methyltransferase in Glehnia littoralis cell cultures. | We investigated whether exogenously supplied precursors of bergapten, namely umbelliferone, psoralen and bergaptol, could be utilized to produce bergapten without elicitation in Glehnia littoralis cell suspension cultures. The levels of added psoralen and bergaptol in the medium soon decreased, and this was followed by... | 18,974,989 |
Is there a need of custom-made prostheses for total hip arthroplasty? Gait analysis, clinical and radiographic analysis of customized femoral components. | Custom-made prosthesis in primary hip arthroplasty based on the concept of a better press-fitting to reach superior clinical results in comparison to conventional implants. Mid-term results provide a more complete picture with respect to gait and electromyographic analyses. The custom-made femoral component (Adaptiva) ... | 18,974,995 |
Lincomycin, rational selection of high producing strain and improved fermentation by amino acids supplementation. | Based on the report that the introduction of the biosynthetic precursor of lincomycin, propylproline, could increase the production of lincomycin (Bruce et al. in US Patent 3,753,859, 1973), a mutant strain pro10-20, with resistance of feedback suppression of proline (an analog of propylproline) was thus selected and l... | 18,975,015 |
Injury to the ulnar collateral ligament of the thumb. | Injury to the ulnar collateral ligament of the thumb is very common and can be disabling when missed or left untreated. We present a review of literature and our preferred way of management. | 18,975,032 |
Blood glucose monitoring is associated with better glycemic control in type 2 diabetes: a database study. | The value of self-monitoring blood glucose (SMBG) in type 2 diabetes is controversial. To determine SMBG testing rates are positively associated with glycemic control in veterans on oral hypoglycemic agents (OHA). Observational database study. Southwestern Healthcare Network veterans taking OHA in 2002 and followed thr... | 18,975,035 |
Is targeted reconstruction necessary for evaluating contrast-enhanced chest computed tomography using a liquid crystal display monitor? | The aim of this study was to examine whether 20-cm field-of-view (FOV) targeted reconstruction (TR) on contrast-enhanced (CE) chest computed tomography (CT) might improve the diagnostic value compared with simple zooming (SZ) from whole-thorax FOV images using a 2 million (2M)-pixel liquid crystal display (LCD) monitor... | 18,975,048 |
HIV-positive persons' awareness and understanding of their state's criminal HIV disclosure law. | Commentary on the potential impact of HIV-specific disclosure laws on persons living with HIV has been critical, plentiful, and enduring. Yet empirical information with which to answer even the most basic questions about these laws, such as whether HIV-positive persons living in a state with a disclosure law are aware ... | 18,975,069 |
Durability of antiviral response in HBeAg-positive chronic hepatitis B patients who maintained virologic response for one year after lamivudine discontinuation. | The purpose of this study is to determine the long-term relapse rate and associated risk factors in HBeAg-positive chronic hepatitis B (CHB) patients who had maintained virologic response (VR) for 1 year after lamivudine (LMV) discontinuation. We enrolled 55 treatment-naive HBeAg-positive CHB patients who achieved and ... | 18,975,080 |
Regulatory T-cell function is impaired in celiac disease. | Celiac disease (CD) is characterized by intolerance to gluten and high risk of developing autoimmune phenomena. Possible defects in immune tolerance could have a role in the pathogenesis of the disease. As regulatory T-cells (Tregs) are the main population involved in maintaining peripheral tolerance, we investigated t... | 18,975,083 |
Role exchange in medical interpretation. | Prior research has documented that medical interpreters engage in non-conduit roles during medical visits. However, agreement on the appropriateness of these roles and their impact on the medical encounter have not yet been achieved. The purpose of this study was to identify non-conduit behavior (role exchange), elucid... | 18,975,091 |
Immunohistochemical analysis of lens cells on formation of different types of age-related cataract in humans. | The aim of the present work was to perform a comparative immunohistochemical study of the ocular lens in normal conditions and after formation of various type of age-related cataract in humans. The control group consisted of lenses from young men dying from accidents and serving as corneal donors (n = 10, not more than... | 18,975,114 |
Effect of plant trichomes on the vertical migration of Haemonchus contortus infective larvae on five tropical forages. | The influence of trichomes on vertical migration and survival of Haemonchus contortus infective larvae (L3) on different forages was investigated. Four different forages showing different distributions of trichomes (Brachiaria brizantha cv. Marandu, Brachiaria brizantha cv. Xaraes, Andropogon gayanus, and Stylosanthes ... | 18,975,119 |
Effect of hepatic cirrhosis on the pharmacokinetics of theophylline in rats. | The experimental hepatic cirrhosis was induced either by bile duct ligation (BDL) or by pretreatment with dimethylnitrosamine (DMNA). The pharmacokinetics of theophylline were studied after a single intravenous or a single oral administration. Using the ultrafiltration method, protein-drug binding experiments were also... | 18,975,172 |
Chongmyungtang attenuates kainic acid-induced seizure and mortal effect in the mouse. | TheChongmyungtang (CMT; the combination ofAcorus gramineus, polygala tenuifolia andPoria cocos) has been recognized to possess the preventive effect against several neurologic disorders in human. In this study, we examined the effect of CMT on the three parameters associated with kainic acid (KA)-induced neurotoxicitie... | 18,975,183 |
Optimal immobilization of penicillinase for lon-selective electrode. | Penicillin sensor was prepared by immobilizing penicillinase (Pcase) on H(+)-selective carboxylated poly (vinyl chloride) (PVC-COOH) membrane or cellulose filter membrane. The immobilization techniques are as follows. Pcase was immobilized with GTH on H(+)-selective PVC-COOH membrane or some amount of BSA was dropped o... | 18,975,214 |
Synthesis and anti-inflammatory and analgesic activities of phenoxyalkanoic acid derivatives. | The synthesis of phenoxyalkanoic acid derivatives and their anti-inflammatory and analgesic activities are described. Analysis of structure-activity relationships shows that in trichlorophenoxy derivatives anti-edematous potency is associated with the presence of 1-thiopropyl moiety and 2 or 4-aminopyridyl moiety at R'... | 18,975,215 |
Isolation of 4,4'-dihydroxybenzyl sulfoxide fromGastrodia elata. | In the course of continous work on tubers ofGastrodia elata, a new constituent, 4,4'-dihydroxybenzyl sulfoxide was isolated from the ethyl acetate soluble fraction prepared from the methanol extract. The structure of the compound was identified from the elemental analytical and spectroscopic data in comparison with tho... | 18,975,220 |
The relationship between hours worked and partner's disability in opposite- and same-sex couples. | When a partner is disabled and not in the labour force, the need for earnings provided by the non-disabled partner increases. However, the disabled partner's need for care raises the value of time spent at home by the non-disabled partner. The direction of the relation between partner disability and hours worked varies... | 18,975,226 |
Avoiding shame: young LGBT people, homophobia and self-destructive behaviours. | This paper reports on findings from qualitative research conducted in the UK that sought to explore the connections between sexual identities and self-destructive behaviours in young people. International evidence demonstrates that there are elevated rates of suicide and alcohol abuse amongst lesbian, gay, bisexual and... | 18,975,229 |
Plasmalemmal and vesicular gamma-aminobutyric acid transporter expression in the developing mouse retina. | Plasmalemmal and vesicular gamma-aminobutyric acid (GABA) transporters influence neurotransmission by regulating high-affinity GABA uptake and GABA release into the synaptic cleft and extracellular space. Postnatal expression of the plasmalemmal GABA transporter-1 (GAT-1), GAT-3, and the vesicular GABA/glycine transpor... | 18,975,268 |
Failure to fully disclose during pretransplant psychological evaluation in alcoholic liver disease: a driving under the influence corroboration study. | The prevention of recidivism in alcoholic liver disease is one of the aims of pretransplant psychological evaluation (PE). Failure to fully disclose the extent of alcohol use is evidence of ongoing alcoholism. Driving under the influence (DUI) represents objective evidence of alcohol abuse, but verifying DUIs through o... | 18,975,271 |
Graft histology characteristics in long-term survivors of pediatric liver transplantation. | The factors that influence the long-term histological outcome of transplanted liver allografts in children are not yet fully understood, and the role of surveillance biopsies in patients with normal graft function remains controversial. The aims of this study were to describe the long-term graft histology of pediatric ... | 18,975,292 |
Detecting lifetime alcohol problems in individuals referred for liver transplantation for nonalcoholic liver failure. | Transplantation for alcoholic liver disease is becoming increasingly common, and with adequate screening, short- to medium-term outcomes are very good. However, while conducting a prospective study of the outcome of liver transplantation in Birmingham, United Kingdom, we observed that a research diagnosis of alcohol ab... | 18,975,295 |
Liver transplantation for hepatoblastoma. | From October 1993 to February 2007, 25 liver transplantations were performed for hepatoblastoma. Of these 25, 18 children received cadaveric grafts, and 7 received left lateral segments from living donors. Fifteen patients were at level IV in the pretreatment extent of disease staging system for hepatoblastoma (PRETEXT... | 18,975,296 |
Severity of baseline magnetic resonance imaging-evident sacroiliitis and HLA-B27 status in early inflammatory back pain predict radiographically evident ankylosing spondylitis at eight years. | Magnetic resonance imaging (MRI) is increasingly used to detect sacroiliitis earlier. This study was undertaken to investigate what proportion of patients with MRI-evident sacroiliitis develop ankylosing spondylitis (AS) in the long term and whether there are predictors of outcome. Consecutive undiagnosed patients with... | 18,975,311 |
Toll-like receptor 2 variants are associated with acute reactive arthritis. | We previously reported a recent outbreak of salmonellosis in which some individuals developed complications of the enteric infection. The objective of this study was to identify genetic variants that might predispose infected individuals to develop articular and/or extraarticular sequelae after Salmonella enteritidis i... | 18,975,326 |
Borrelia burgdorferi NapA-driven Th17 cell inflammation in lyme arthritis. | Human Lyme arthritis caused by Borrelia burgdorferi is characterized by an inflammatory infiltrate that consists mainly of neutrophils and T cells. This study was undertaken to evaluate the role of the innate and acquired immune responses elicited by the neutrophil-activating protein A (NapA) of B burgdorferi in patien... | 18,975,343 |
No dead certainties? | In July the NHS published mortality rates on four operations. Health professionals are still divided on the benefits of publishing these. How the public will understand and use such outcome rates remains uncertain. | 18,975,435 |
Intracranial epidermoid--a 10-year study. | Twenty-eight cases of intracranial epidermoids were operated over a period of 10 years at the Bangur Institute of Neurology, Kolkata; 17 of them were male and 11 were female with an age range of 11 to 55 (mean 28.21) years. Their locations include--cerebellopontine angle region (n = 15), fourth ventricle (n = 6), later... | 18,975,500 |
Acute intermittent porphyria presenting as acute pancreatitis and posterior reversible encephalopathy syndrome. | Acute intermittent porphyria (AIP) is an inherited metabolic disease that can affect the autonomic, peripheral and central nervous systems. Pancreatic diseases assocated with AIP is rarely reported. We report here a 60-year-old non-alcoholic male who had typical manifestations of AIP, including abdominal pain, constipa... | 18,975,524 |
Hypereosinophilic syndrome with recurrent strokes: a case report. | Hypereosinophilic syndrome is a rare disorder which can cause ischemic stroke. Although cardioembolism is acknowledged as the most common etiology for stroke, the underlying pathogenesis of hypereosinophilic syndrome could be heterogeneous. Herein we describe a patient with persistent hypereosnophillia with recurrent s... | 18,975,525 |
[Sudden vocal cord closure during general anesthesia using remifentanil]. | We experienced three cases of ventilatory difficulty through a Proseal laryngeal mask airway was encountered during general anesthesia using remifentanil and sevoflurane. General anesthesia was induced with propofol and maintained with remifentanil (0.2-0.25 microg x kg(-1) x min(-1)) and sevoflurane (1-1.5%). Increase... | 18,975,534 |
[Comparative study of sublingual midazolam with oral midazolam for premedication in pediatric anesthesia]. | We studied the efficacy of sublingual midazolam compared with oral midazolam for predmedication in children. Forty-two children (9 months-11 years of age) for minor elective surgery were divided into 2 groups; one group treated with sublingual midazolam at 30 minutes before the entrance into operating room, and the oth... | 18,975,537 |
[To distinguish true glottic opening using laryngoscope is very difficult for probationers]. | The video intubating laryngoscope (VIL) can share information with co-workers, that otherwise only one probationer could obtain. Tracheal intubation was reviewed using recorded videotapes via VIL. It was supposed that the esophageal changes by laryngoscope might cause esophageal intubation. In this study, we investigat... | 18,975,551 |
[Relationship between glycated albumin (GA) and glycated hemoglobin (A1c) in 255 patients with liver diseases using cross-sectional laboratory data]. | To investigate how liver disease alter the serum glycated proteins as markers of diabetic control, we studied serum GA, A1c and especially GA/A1c ratio in 255 patients having over 35IU/L in ALT(transaminase) compared with those of 829 type 2 diabetes mellitus (DM) in cross sectional manner. 255 patients with liver dise... | 18,975,554 |
[Neutrophil function tests and oxidative stress detection as clinical examinations]. | We herein introduce several clinically available methods to detect neutrophil function and oxidative stress. The flowcytometric detection of adhesive protein expression, such as CD11b(Mac-1), assessment of phagocytosis activity, and measurement of reactive oxygen species (ROS) production are relatively easy to apply as... | 18,975,558 |
[Role of coil embolization and arterial injection in elderly subarachnoid hemorrhage patients: preliminary report]. | With the recent advanced aging seen in society, the number of elderly patients with aneurismal subarachnoid hemorrhage (SAH) is increasing. We focused on current management of SAH in patients who were over 75 years old. From January 1st, 2004 to the end of June, 2007, we had treated 170 SAH patients including 39 who we... | 18,975,562 |
[Case of large sphenoid ridge meningioma treated by 2-stage surgery]. | Large skull base meningiomas frequently encase the major cerebral vessels and cranial nerves, and receive blood supply from the branches of the internal carotid artery. One-stage resection of these tumors is difficult due to the long time needed for surgery and profuse bleeding from the tumor. We report herein a case o... | 18,975,564 |
[Combination therapy consisting of gemcitabine, docetaxel and carboplatin as a second-line chemotherapy for patients with MVAC-treated metastatic urothelial carcinoma]. | From 2001 to 2006, 11 patients with MVAC-treated metastatic urothelial carcinoma received as a second-line therapy GDC therapy consisting of gemcitabine (1,000 mg/m2) on day land 8, docetaxel (80 mg/m2) on day 1 and carboplatin (AUC 5) on day 1 in each 21-day cycle. The 11 patients received a total of 42 cycles. The me... | 18,975,570 |
[Case of bilateral renal cell carcinoma with the tumor thrombus in the inferior vena cava]. | We describe a case of bilateral renal cell carcinoma with the tumor thrombus in the inferior vena cava. A 71-year-old male was admitted to our department for, careful examination of bilateral renal tumors. Abdominal computed tomography (CT) revealed bilateral solid enhanced renal masses with the tumor thrombus in the i... | 18,975,575 |
[Sensorineural deafness in Guillain-Barré syndrome]. | The patient was a 31-year-old woman in whom facial paralysis occurred 1 week after the onset of pyelonephritis. Peripheral facial paralysis, sensorineural deafness, dysarthria, weakness of the four limbs, loss of tendon reflex, and peripheral sensory disturbance of the four limbs were noted during the initial examinati... | 18,975,606 |
Changes in the properties of secretory granules in the palatine gland acinar cells of the postnatally developing rat. | This study was designed to examine whether or not phospholipid is contained in the secretory granules of the rat palatine gland acinar cells, and if present, to examine the movements of phospholipid in the secretory granules during postnatal development. The palatine glands of male Wistar rats aged 0 to 56 days were us... | 18,975,612 |
Sensory processing patterns and daily activity preferences of Israeli children. | One determinant of participation is activity preferences, which may be influenced by sensory processing patterns. To compare daily activity preferences of Israeli children who have typical versus atypical sensory processing patterns, according to age and gender. Twenty-five children with atypical sensory processing pat... | 18,975,668 |
[Retrospective study of a method of automobile driving evaluation in adult mental health]. | In adult mental health, there are few practice guidelines for occupational therapists with regards to the assessment of driving capacities. This article describes a clinical approach, with regards to driving assessments, in adult mental health. A retrospective study was completed from a chart review of clients seen in ... | 18,975,669 |
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