title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Lifetime and during pregnancy experience of violence and the risk of low birth weight and preterm birth. | In order to assess the relationship between lifetime and during pregnancy experience of violence and low birth weight (LBW) and preterm birth outcomes, we designed a prospective cohort study in which the birth outcomes of women who experienced violence before their pregnancy or who experienced violence during pregnancy... | 18,984,508 |
Perceived changes in health and safety following participation in a health care-based domestic violence program. | This descriptive study explores perceived changes in health and safety and the potential process by which these changes occur. Forty-nine women experiencing intimate partner abuse participated in a health care-based domestic violence (DV) advocacy program for 6 months or more. An analysis of structured interviews in En... | 18,984,511 |
Rural mothers experiencing the stress of intimate partner violence or not: their newborn health concerns. | Pregnancy and the postpartum period is a time of great physical, psychological, and emotional upheaval. Women who experience intimate partner violence experience more depression and anxiety and a higher risk of adverse pregnancy outcomes (such as those related to the abuse). While the literature supports the presence o... | 18,984,512 |
Who is willing to use complementary and alternative medicine? | The aim of this study was to identify individual differences associated with the willingness to use complementary and alternative medicine (CAM). A questionnaire was administered and the relationship between individual differences and the willingness to use CAM was examined using correlation and multiple regression ana... | 18,984,547 |
Exploring biological relationships between calving traits in primiparous cattle with a Bayesian recursive model. | Structural equation models (SEMs) of a recursive type with heterogeneous structural coefficients were used to explore biological relationships between gestation length (GL), calving difficulty (CD), and perinatal mortality, also known as stillbirth (SB), in cattle, with the last two traits having categorical expression... | 18,984,571 |
Population genetic inference from resequencing data. | This article is concerned with statistical modeling of shotgun resequencing data and the use of such data for population genetic inference. We model data produced by sequencing-by-synthesis technologies such as the Solexa, 454, and polymerase colony (polony) systems, whose use is becoming increasingly widespread. We sh... | 18,984,575 |
Molecular basis of the interaction of Saccharomyces cerevisiae Eaf3 chromo domain with methylated H3K36. | Eaf3 is a component of both NuA4 histone acetyltransferase and Rpd3S histone deacetylase complexes in Saccharomyces cerevisiae. It is involved in the regulation of the global pattern of histone acetylation that distinguishes promoters from coding regions. Eaf3 contains a chromo domain at the N terminus that can bind to... | 18,984,594 |
G2Cdb: the Genes to Cognition database. | Neuroscience databases linking genes, proteins, (patho)physiology, anatomy and behaviour across species will be valuable in a broad range of studies of the nervous system. G2Cdb is such a neuroscience database aiming to present a global view of the role of synapse proteins in physiology and disease. G2Cdb warehouses se... | 18,984,621 |
Acute toxicity of organophosphorus compounds in guinea pigs is sex- and age-dependent and cannot be solely accounted for by acetylcholinesterase inhibition. | This study was designed to test the hypothesis that the acute toxicity of the nerve agents S-[2-(diisopropylamino)ethyl]-O-ethyl methylphosphonothioate (VX), O-pinacolyl methylphosphonofluoridate (soman), and O-isopropyl methylphosphonofluoridate (sarin) in guinea pigs is age- and sex-dependent and cannot be fully acco... | 18,984,651 |
Effect of novel negative allosteric modulators of neuronal nicotinic receptors on cells expressing native and recombinant nicotinic receptors: implications for drug discovery. | Allosteric modulation of nAChRs is considered to be one of the most promising approaches for drug design targeting nicotinic acetylcholine receptors (nAChRs). We have reported previously on the pharmacological activity of several compounds that seem to act noncompetitively to inhibit the activation of alpha3beta4(*) nA... | 18,984,653 |
Absence of somatic SQSTM1 mutations in Paget's disease of bone. | Paget's disease is a common focal bone disorder that appears to be caused by a combination of genetic and environmental factors. Mutations in the SQSTM1 gene are found in about one third of families with Paget's disease and 8% of sporadic cases. Other potential loci linked to the disease have also been identified, and ... | 18,984,666 |
Hellea balneolensis gen. nov., sp. nov., a prosthecate alphaproteobacterium from the Mediterranean Sea. | A novel aerobic, heterotrophic, prosthecate bacterium, designated 26III/A02/215(T), was isolated from surface water of the north-western Mediterranean Sea. Cells stained Gram-negative and were straight to slightly curved rods, forming red colonies on agar plates. The strain grew at 15-37 degrees C inclusive (optimum 30... | 18,984,685 |
Thermoanaerobacter uzonensis sp. nov., an anaerobic thermophilic bacterium isolated from a hot spring within the Uzon Caldera, Kamchatka, Far East Russia. | Several strains of heterotrophic, anaerobic thermophilic bacteria were isolated from hot springs of the Uzon Caldera, Kamchatka, Far East Russia. Strain JW/IW010(T) was isolated from a hot spring within the West sector of the Eastern Thermal field, near Pulsating Spring in the Winding Creek area. Cells of strain JW/IW0... | 18,984,694 |
Leucobacter tardus sp. nov., isolated from the phyllosphere of Solanum tuberosum L. | In the course of studying the composition of the microbial community in the phyllosphere of potato plants, a Gram-positive bacterium, strain K 70/01(T), was isolated. On the basis of 16S rRNA gene sequence analysis, it was shown that the investigated isolate represents a novel species in the genus Leucobacter; the clos... | 18,984,695 |
Photorhabdus temperata subsp. cinerea subsp. nov., isolated from Heterorhabditis nematodes. | During the characterization of symbiotic bacteria of Hungarian entomopathogenic nematode isolates, a number of bacteria (including strain 3107(T)) isolated from Heterorhabditis downesi and Heterorhabditis megidis showed only moderate 16S rRNA gene sequence similarity to the type strains of all described Photorhabdus sp... | 18,984,696 |
Bacillus alkalitelluris sp. nov., an alkaliphilic bacterium isolated from sandy soil. | A Gram-positive, alkaliphilic bacterium, designated strain BA288(T), was isolated from sandy soil. Cells were facultatively anaerobic, endospore-forming rods that were motile by means of peritrichous flagella. The strain grew at 15-40 degrees C and pH 7.0-11.0 (optimally at 30 degrees C and pH 9.0-9.5) and at salinitie... | 18,984,705 |
Taxonomic analysis of Sorangium strains based on HSP60 and 16S rRNA gene sequences and morphology. | The taxonomy of myxobacteria is based mainly on their morphological characteristics. The genus Sorangium belongs to the myxobacterial suborder Sorangiineae. Strains in the genus were classified either as one species, Sorangium cellulosum, by ignoring divergent morphological characteristics, or into several species; how... | 18,984,709 |
All-trans retinoic acid inhibits type 1 diabetes by T regulatory (Treg)-dependent suppression of interferon-gamma-producing T-cells without affecting Th17 cells. | All-trans retinoic acid (ATRA), a potent derivative of vitamin A, can regulate immune responses. However, its role in inducing immune tolerance associated with the prevention of islet inflammation and inhibition of type 1 diabetes remains unclear. We investigated the mechanisms underlying the potential immunoregulatory... | 18,984,738 |
Can 64-row computed tomography replace angiography after coronary bypass? | Multi-detector (64-row) computed tomography has become an alternative to coronary angiography to diagnose graft occlusion and stenosis after coronary artery bypass. We compared the power of evaluation of multi-detector computed tomography with that of conventional coronary angiography in 60 patients who underwent coron... | 18,984,751 |
Off-pump coronary revascularization for left main coronary artery stenosis. | Experience of on- and off-pump coronary artery bypass in 379 patients with significant left main coronary artery stenosis was retrospectively reviewed. Beating-heart operations were performed on 219 patients between January 2001 and October 2007. Their results were compared with 160 who underwent revascularization unde... | 18,984,757 |
Smooth or attached solid indeterminate nodules detected at baseline CT screening in the NELSON study: cancer risk during 1 year of follow-up. | To retrospectively determine whether baseline nodule characteristics at 3-month and 1-year volume doubling time (VDT) are predictive for lung cancer in solid indeterminate noncalcified nodules (NCNs) detected at baseline computed tomographic (CT) screening. The study, conducted between April 2004 and May 2006, was inst... | 18,984,780 |
Plasticity of cloned canine mammary spindle cell tumor, osteosarcoma and carcinoma cells. | Female dogs are frequently affected by mammary tumors, both carcinomas and sarcomas. The mechanisms behind mammary-tumor formation and the high degree of heterogeneity are not understood. To provide insight into this issue, it is important to determine the properties of the cells forming the different types of tumors. ... | 18,984,783 |
Review paper: modulation of mononuclear phagocyte function by Mycobacterium avium subsp. paratuberculosis. | Pathogenic mycobacteria are highly adapted for survival within host mononuclear phagocytes. This is largely due to the organism's capacity to prevent macrophage activation, block phagosome acidification and maturation, and attenuate presentation of antigens to the immune system. Mycobacterium avium subsp. paratuberculo... | 18,984,786 |
Review paper: a review of the pathology of abnormal placentae of somatic cell nuclear transfer clone pregnancies in cattle, sheep, and mice. | Cloning of cattle, sheep, and mice by somatic cell nuclear transfer (SCNT) can result in apparently healthy offspring, but the probability of a successful and complete pregnancy is less than 5%. Failures of SCNT pregnancy are associated with placental abnormalities, such as placentomegaly, reduced vascularisation, hypo... | 18,984,789 |
Staphylococcus-associated abortions in ewes with long-term central venous catheterization. | Forty-two ewes had an intravenous catheter sewn in place in a prepared area over the jugular vein and beginning at 60 days of gestation received an infusion 3 times daily. The infusion consisted of sterile saline or sterile saline containing arginine. Twenty-six ewes in both control and treatment groups aborted between... | 18,984,790 |
Biphasic malignant testicular sex cord-stromal tumor in a cotton-top tamarin (Saguinus oedipus) with review of the literature. | A 20-year old male cotton-top tamarin (Saguinus oedipus) was presented with unilateral enlargement of an intrascrotal testicle. Fine-needle aspiration cytology demonstrated a neoplastic population with Call-Exner-like bodies and features of malignancy. The animal was castrated, and histologic examination revealed a bip... | 18,984,797 |
Anaplastic astrocytoma in the spinal cord of an African pygmy hedgehog (Atelerix albiventris). | A 2-year-old, female hedgehog presented with an 8-month history of progressive, ascending paresis/paralysis and was tentatively diagnosed with wobbly hedgehog syndrome. She died awaiting further diagnostic tests, and the owners consented to postmortem examination. Grossly, the bladder was large and flaccid and the cerv... | 18,984,799 |
Genetic structure of the asiatic black bear in Japan using mitochondrial DNA analysis. | The genetic structure of the Asiatic black bear (Ursus thibetanus) in Japan was studied to understand the events that occurred during its evolution. The left domain of the mitochondrial control region (about 240 bp) was sequenced, defining 27 haplotypes that consisted of 23 haplotypes from 333 bears in Japan and 22 bea... | 18,984,857 |
NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity. | Understanding the pathways that regulate the human T-cell acute lymphoblastic leukemia (T-ALL) initiating cells (T-LiC) activity has been hampered by the lack of biologic assays in which this human disease can be studied. Here we show that coculture of primary human T-ALL with a mouse stromal cell line expressing the N... | 18,984,862 |
Challenges in conducting a hospital-randomized trial of an educational quality improvement intervention in rural and small community hospitals. | The study design for this hospital-randomized controlled trial of an educational quality improvement intervention in rural and small community hospitals, following the implementation of a Web-based quality benchmarking and case review tool, specified a control group and a rapid-cycle quality improvement education group... | 18,984,908 |
Study of Prevalence, Awareness,and control of Hypertension in a Suburban Area of Kathmandu, Nepal. | BACKGROUND, In the context of rapidly raising occurrence of cardiovascular diseases in the developing countries, it becomes imperative to study the scenario in its various aspects. The present study in Nepal deals with the hypertension as it is one of the major risk factors of cardiovascular diseases. METHODS AND RESUL... | 18,984,928 |
Alveolar macrophage from cigarette smoke-exposed mice inhibits B lymphocyte proliferation stimulated with LPS. | Smokers have higher incidences of pulmonary diseases. This increased susceptibility may result from cigarette smoke (CS)-induced impairment of the pulmonary immune system. However, the mechanism(s) is not fully understood. The aim of this study was to investigate the mechanism of the effect of alveolar macrophages (AM)... | 18,984,945 |
Noninvasive depiction of the lenticulostriate arteries with time-of-flight MR angiography at 7.0 T. | The lenticulostriate arteries (LSAs) are small penetrating branches which are feeding the basal ganglia. Thus far, no noninvasive imaging method has been capable of visualizing the LSAs. We explore the possibilities of three-dimensional time-of-flight (TOF) MR angiography (MRA) at 7 T to visualize the LSAs. We included... | 18,984,947 |
Heparin-induced thrombocytopenia: a serious complication of heparin therapy for acute stroke. | Despite the lack of supporting evidence, unfractionated heparin (UFH) is frequently given to acute ischemic stroke patients. This study was designed to determine the incidence of heparin-induced thrombocytopenia (HIT) during acute stroke and to elucidate the clinical features of stroke patients with HIT. Of 1,078 conse... | 18,984,950 |
Presence and extent of cardiac magnetic resonance microvascular obstruction in reperfused non-ST-elevated myocardial infarction and correlation with infarct size and myocardial enzyme release. | Microvascular obstruction (MO) is a factor of adverse outcome in patients with ST-elevated myocardial infarction (STEMI). We assessed the presence and extent of MO and its relationship with infarct size and left ventricular (LV) functional parameters after acute non-ST-elevated myocardial infarction (NSTEMI). Twenty-fi... | 18,984,954 |
The effect of volume of chorionic villi on long-term cell culture. | It was the aim of our study to investigate the association between culture time and weight of villi obtained by transabdominal chorionic villus sampling (CVS). We analyzed 1,442 villus samples. The gestational age at sampling ranged from 10 to 14 weeks. The weight of villi in these samples ranged from 1 to 80 mg (media... | 18,984,962 |
[A case of Hennekam syndrome presenting with massive pericardial effusion]. | Hennekam syndrome is an autosomal recessive disease characterized by intestinal lymphangiectasia accompanied by severe lymphedema of the limbs, genitalia, and face, and learning difficulties. A 38-month-old boy was admitted with breathing difficulty. He had facial abnormalities and preputial hyperplasia consistent with... | 18,984,984 |
A case of simultaneous anterior, inferior, and right ventricular ST-segment elevation myocardial infarction due to occlusion of the wrapped left anterior descending coronary artery. | Simultaneous anterior, inferior, and right ventricular ST-segment elevation myocardial infarction is an unusual condition. A 50-year-old male patient presented with severe, squeezing chest pain of an hour onset. ST-segment elevations were detected in all precordial derivations, DII, DIII, aVF and V3R, V4R. Coronary ang... | 18,984,987 |
Development of left ventricular apical akinesis and thrombus during pericardiocentesis for pericardial tamponade. | Although pericardiocentesis is a more practical and comfortable alternative to surgical drainage in patients with pericardial tamponade, it may sometimes be associated with transient ventricular dysfunction due to rapid drainage of the fluid. We presented a 42-year-old female patient who developed left ventricular syst... | 18,984,988 |
[Audiological evaluation of a child with Klippel-Feil syndrome]. | A 6-year-old boy with formerly diagnosed Klippel-Feil syndrome (KFS) presented with complaints of hearing loss, speech disorder, and problems related to his hearing aid. Clinical examination and computed tomography showed bilateral external and middle ear anomalies and audiological examination revealed bilateral severe... | 18,984,999 |
RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells. | Osteopontin (OPN) is a secreted phosphoprotein which mediates tumorigenesis, local growth, and metastasis in a variety of cancers. It is a potential therapeutic target for the regulation of cancer metastasis. RNA aptamer technology targeting OPN may represent a clinically viable therapy. In this study, we characterize ... | 18,985,031 |
Robust prognostic value of a knowledge-based proliferation signature across large patient microarray studies spanning different cancer types. | Tumour proliferation is one of the main biological phenotypes limiting cure in oncology. Extensive research is being performed to unravel the key players in this process. To exploit the potential of published gene expression data, creation of a signature for proliferation can provide valuable information on tumour stat... | 18,985,037 |
2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: a potential treatment for breast and prostate cancer. | Drug combination therapy is a key strategy to improve treatment efficacy and survival of cancer patients. In this study the effects of combining 2-methoxyoestradiol-3,17-O,O-bis-sulphamate (STX140), a microtubule disruptor, with 2-deoxy-D-glucose (2DG) were assessed in MCF-7 (breast) and LNCaP (prostate) xenograft mode... | 18,985,042 |
Structural variation in Xq28: MECP2 duplications in 1% of patients with unexplained XLMR and in 2% of male patients with severe encephalopathy. | Duplications in Xq28 involving MECP2 have been described in patients with severe mental retardation, infantile hypotonia, progressive spasticity, and recurrent infections. However, it is not yet clear to what extent these and accompanying symptoms may vary. In addition, the frequency of Xq28 duplications including MECP... | 18,985,075 |
Alternative mechanisms for regulating racial responses according to internal vs external cues. | Personal (internal) and normative (external) impetuses for regulating racially biased behaviour are well-documented, yet the extent to which internally and externally driven regulatory processes arise from the same mechanism is unknown. Whereas the regulation of race bias according to internal cues has been associated ... | 18,985,098 |
Increased feelings with increased body signals. | Since the beginning of psychology as a scientific endeavour, the question of whether the body plays a role in how a person experiences emotion has been the centre of emotion research. Patients with structural gastrointestinal disorders, such as Crohn's disease, provide an intriguing opportunity to study the influence o... | 18,985,099 |
Model syndromes for investigating social cognitive and affective neuroscience: a comparison of Autism and Williams syndrome. | Autism and Williams syndrome are genetically based neurodevelopmental disorders that present strikingly different social phenotypes. Autism involves fundamental impairments in social reciprocity and communication, whereas people with Williams syndrome are highly sociable and engaging. This article reviews the behaviora... | 18,985,104 |
The liver and the moral organ. | Drawing on an analogy to language, I argue that a suite of novel questions emerge when we consider our moral faculty in a similar light. In particular, I suggest the possibility that our moral judgments are derived from unconscious, intuitive processes that operate over the causal-intentional structure of actions and t... | 18,985,108 |
Music and mirror neurons: from motion to 'e'motion. | The ability to create and enjoy music is a universal human trait and plays an important role in the daily life of most cultures. Music has a unique ability to trigger memories, awaken emotions and to intensify our social experiences. We do not need to be trained in music performance or appreciation to be able to reap i... | 18,985,111 |
Mechanisms underlying sexual and affiliative behaviors of mice: relation to generalized CNS arousal. | The field of social neuroscience has grown dramatically in recent years and certain social responses have become amenable to mechanistic investigations. Toward that end, there has been remarkable progress in determining mechanisms for a simple sexual behavior, lordosis behavior. This work has proven that specific hormo... | 18,985,112 |
Studying mind and brain with fMRI. | The explosion in publications using functional magnetic resonance imaging (fMRI) warrants an examination of how the technique is being used to study processes of mind and brain. Here, we propose a classification of fMRI studies that reveals how this technique is being used in the service of understanding psychological ... | 18,985,126 |
No global processing deficit in the Navon task in 14 developmental prosopagnosics. | Faces are represented in a more configural or holistic manner than other objects. Substantial evidence indicates that this representation results from face-specific mechanisms, but some have argued that it is produced by configural mechanisms that can be applied to many objects including words. The face-specific hypoth... | 18,985,129 |
Elevated stress-hemoconcentration in major depression is normalized by antidepressant treatment: secondary analysis from a randomized, double-blind clinical trial and relevance to cardiovascular disease risk. | Major depressive disorder (MDD) is an independent risk factor for cardiovascular disease (CVD); the presence of MDD symptoms in patients with CVD is associated with a higher incidence of cardiac complications following acute myocardial infarction (MI). Stress-hemoconcentration, a result of psychological stress that mig... | 18,985,146 |
Allene-alkyne cross-coupling for stereoselective synthesis of substituted 1,4-dienes and cross-conjugated trienes. | Titanium-mediated cross-coupling of allenic alcohols with alkynes has been investigated. Divergent reaction pathways were discovered that provide either stereodefined 1,4-dienes or substituted cross-conjugated trienes. In short, allene substitution plays a critical role in the determination of reaction pathway. | 18,985,173 |
Evaluating the human likeness of an android by comparing gaze behaviors elicited by the android and a person. | Our research goal is to discover the principles underlying natural communication among individuals and to establish a methodology for the development of expressive humanoid robots. For this purpose we have developed androids that closely resemble human beings. The androids enable us to investigate a number of phenomena... | 18,985,174 |
Pre-programmed bicomponent porous networks at the solid-liquid interface: the low concentration regime. | The control over the formation of a bicomponent porous network was attained by self-assembly at the solid-liquid interface, exploiting triple H-bonds between melamine and bis-uracyl modules. | 18,985,186 |
An unexpected ruthenium complex and its unique behavior as catalyst in dynamic kinetic resolution of secondary alcohols. | A ruthenium complex was accidentally synthesized and its unique catalytic behavior in dynamic kinetic resolution of various types of secondary alcohols, particularly for those bearing additional functional groups, is described. | 18,985,201 |
A metallopolymer case-history: polymer, ring or ligand reaction? | Multinuclear cobalt(II) complexes of ditopic ligands with alpha,omega-dioxy spacers linking two tpy metal-binding domains react with alcohols to generate mononuclear 4'-alkoxy-species. | 18,985,210 |
Rhodium-catalysed cyclisation reaction of allenynes with arylboronic acids. | Allenynes having malonate-based tethers reacted with arylboronic acids in the presence of a rhodium(I) catalyst to sequentially form three carbon-carbon bonds, and arylated bicyclic skeletons were constructed in a stereoselective manner. | 18,985,212 |
Deprotonative cadmation of functionalized aromatics. | This communication describes the deproto-metalation of a large range of aromatics including heterocycles using a newly developed lithium-cadmium base; the reaction proceeds at room temperature with an excellent chemoselectivity and efficiency, and proved to be regioselective in most cases. | 18,985,215 |
Self-assembly of amphiphilic poly(phenylene ethynylene)s in water-potassium dodecanoate-decanol lyotropic liquid crystals. | Poly(phenylene ethynylene)s bearing a high density of branched amphiphilic side-chains self-assemble at the air-water interface and in water-potassium dodecanoate-decanol lyotropic liquid crystals. | 18,985,219 |
Different effects of Fe2+ and Fe3+ on conjugated polymer PPESO3: a novel platform for sensitive assays of hydrogen peroxide and glucose. | Fe(2+) and Fe(3+) as a redox pair showing different effects on a water-soluble conjugated polymer PPESO(3) is definitely an interesting and useful phenomenon in view of signal transduction and has been utilized to develop sensitive assays of hydrogen peroxide and glucose. | 18,985,228 |
A novel type of N-formylation and related reactions of amines via cyanides and esters as formylating agents. | A novel N-formylation and related reactions proceed from cyanides promoted by esters. | 18,985,233 |
The role of "external" lone pairs in the chemical bonding of bare post-transition element clusters: the Wade-Mingos rules versus the jellium model. | The jellium sphere model of a volume of electrons, counterbalanced by a positive charge throughout the sphere, leads to an energy level sequence corresponding to special stabilities of bare post-transition element clusters with 20 valence electrons such as the known P4 and clusters with 40 valence electrons such as the... | 18,985,236 |
Reactivity of UH3 with mild oxidants. | Addition of 2 equiv of I2 to a stirring suspension of UH3 in Et2O results in vigorous gas evolution and the formation of UI4(OEt2)2 (1), which can be isolated in good yields as an air- and moisture-sensitive brick-red powder. Addition of 3 equiv of AgBr to UH3 in DME produces UBr3(DME)2 (2), while addition of 4 equiv o... | 18,985,243 |
Bisursodeoxycholate(ethylenediamine)platinum(II): a new autofluorescent compound. Cytotoxic activity and cell cycle analysis in ovarian and hematological cell lines. | The present paper describes for the first time an intrinsic fluorescent square-planar platinum(II) complex carrying two ursodeoxycholate ligands ([Pt(UDC)2(en)], where UDC(-) = ursodeoxycholate), that emits at room temperature once free in solution. Kinetic studies were carried out in aqueous solution and in the presen... | 18,985,248 |
Urinary symptoms and impact on quality of life in women after treatment for endometrial cancer. | The primary objective of our study is to describe urinary symptoms in women treated for endometrial cancer. We performed a cross-sectional survey of women who had undergone surgical treatment for endometrial cancer. Three validated questionnaires were utilized: the Sandvik Severity Index, the Urinary Distress Inventory... | 18,985,266 |
Analysis of the extent of resection for adenocarcinoma of the gallbladder. | Gallbladder cancer has historically been considered an incurable malignancy; although, extended resection has been associated with cure in selected patients. However, the optimal extent of resection is unknown. The objective of this study was to analyze the impact of the extent of resection for gallbladder adenocarcino... | 18,985,272 |
Abortiporus biennis tolerance to insoluble metal oxides: oxalate secretion, oxalate oxidase activity, and mycelial morphology. | The ability of Abortiporus biennis to tolerate and solubilize toxic metal oxides (Cu(2)O, Al(2)O(3), ZnO, CuFe(2)O(4)Zn, CdO, and MnO(2)) incorporated into agar media was investigated and the growth rate, oxalic acid secretion, and mycelial morphology were monitored. Among the tested metal oxides, formation of clear zo... | 18,985,279 |
The role of the "International Classification of Functioning, Disability and Health, ICF" in the description and classification of mental disorders. | Diagnoses according to ICD-10 or DSM are conclusions derived from diagnostic algorithms, based on symptoms, but also illness course, history and consequences of the illness state. But, there is only limited consensus about the definitions of the criteria which are the basis of diagnostic algorithms. In DSM there is onl... | 18,985,301 |
Interaction between noradrenaline and corticotrophin-releasing factor in the reinstatement of cocaine seeking in the rat. | Corticotropin-releasing factor (CRF) and noradrenaline (NA) have been shown in independent studies to mediate stress-induced reinstatement of drug seeking. To date, however, a functional interaction between the systems in reinstatement has not been demonstrated. The objectives of this study were to determine whether CR... | 18,985,323 |
Osteolysis with a cementless second generation metal-on-metal cup in total hip replacement. | This study examined the long-term results of a metal-on-metal total hip replacement with a Metasul-lined cup. Twenty-nine total hip arthroplasties were performed in 27 young patients (mean age 49 years). Twenty-two patients (23 hips) were available for clinical and radiographic analysis after a mean duration of 99 mont... | 18,985,349 |
Seasonal variations of pH, pCO2, pO2, HCO3- and Ca2+ in the haemolymph: implications on the calcification physiology in Anodonta cygnea. | A study about the relationship between the physical-chemical parameters and the calcium carbonate balance between the haemolymph fluid and mantle calcareous structures was carried out in Anodonta cygnea. An intense peak of HCO(3) (-) and a highest pH in December-January months may be understood as a preparation period ... | 18,985,356 |
Significance of pulmonary artery size and blood flow as a predictor of outcome in congenital diaphragmatic hernia. | To determine if pulmonary artery size and blood flow have prognostic value in congenital diaphragmatic hernia (CDH). Twenty-eight consecutive left-sided CDH patients treated according to a standard protocol with high frequency oscillatory ventilation (HFOV) + nitric oxide (NO) had right and left pulmonary artery (RPA, ... | 18,985,361 |
Detailed analysis of retinal function and morphology in a patient with autosomal recessive bestrophinopathy (ARB). | The objective of the paper is to study the retinal microstructure and function in a patient with autosomal recessive bestrophinopathy (ARB). Retinal function and morphology assessment in a patient diagnosed with a biallelic mutation in the BEST1 gene (heterozygote mutations: Leu88del17 and A195V) included: full-field e... | 18,985,398 |
[Validation of secondary data. Strengths and limitations]. | Medical records databases (such as the General Practice Research Database-GPRD) and administrative databases (such as German Statutory Health Insurance (SHI) claims data) are useful sources for pharmacoepidemiology and health services research. However, these data are not primarily collected for research purposes. Vali... | 18,985,405 |
Cell volume as a factor limiting the replicative lifespan of the yeast Saccharomyces cerevisiae. | The number of cell divisions of the yeast Saccharomyces cerevisiae is limited, referred to as "replicative lifespan" of this organism and believed to be due to aging mechanisms similar to those of mammalian cells. We demonstrate, using three pairs of isogenic yeast strains (standard and a mutant deficient in an antioxi... | 18,985,429 |
Octreotide uptake in intracranial metastasis of pancreatic ductal adenocarcinoma origin in a patient with a prolonged clinical course. | We describe a case with prolonged survival of 2 years in a female patient with pancreatic ductal adenocarcinoma who, at diagnosis, already had liver spread and eventually succumbed to brain metastases which scanned positive with [(111)In-DTPA] octreotide scintiscan (OctreoScan). Subsequently, the patient underwent a cr... | 18,985,450 |
Risperidone safety in pregnancy. A case report. | The use of risperidone and other antipsychotic drugs during pregnancy is sometimes essential, although it is impossible to design clinical trials to demonstrate the safety of these kinds of drugs. The common method to communicate the absence of drug-related events is through case reports, even though they might be insu... | 18,985,459 |
Accurate ALSFRS-R scores can be generated from retrospective review of clinic notes. | Retrospective studies are important in ALS but require markers of disease severity to enable risk adjustment and to allow fair comparisons between patient groups. The ALSFRS-R could be used as such a measure. This study aimed to determine if accurate ALSFRS-R scores could be generated by reviewing clinic notes. Five in... | 18,985,465 |
Fetal liver-conditioned medium induces hepatic specification from mouse bone marrow mesenchymal stromal cells: a novel strategy for hepatic transdifferentiation. | Although different strategies have been established for hepatic differentiation of mesenchymal stromal cells (MSC), further studies are required to define an efficient strategy to produce hepatocytes from stem cells and uncover the mechanisms of hepatic differentiation. Bone marrow mesenchymal stromal cells (BMMSC), is... | 18,985,473 |
Pre-clinical safety testing supporting clinical use of allogeneic multipotent adult progenitor cells. | Successful clinical development of novel cellular therapeutics requires the evaluation of clinical acute toxicity endpoints in scoring patient adverse events (AE) contributing to dose-limiting toxicity (DLT) for establishment of the maximum-tolerated dose (MTD). However, many clinical pathology parameters are not routi... | 18,985,479 |
A new C21 steroidal glycoside from Cynanchum inamoenum (Maxim.) Loes. | A new C21 steroidal glycoside, 5beta,6beta-epoxy-glaucogenin C-3-O-beta-D-glucopyranosyl-(1 --> 4)-beta-d-glucopyranosyl-(1 --> 4)-beta-D-cymaropyranosyl-(1 --> 4)-beta-D-oleandropyranosyl-(1 --> 4)-beta-D-oleandropyranoside, named inamoside D (1), was isolated from the MeOH extract of the roots of Cynanchu... | 18,985,499 |
[Investigation of Demodex sp. using cellophane tape method among university students]. | Demodex sp. is an obligatory ectoparasite of pilosebaceous units in humans. This study was carried out in order to investigate the frequency of Demodex sp. among high school students. For this purpose 75 women and 96 men, making a total of 171 students, were studied. Cellophane-tape preparations taken from their face, ... | 18,985,578 |
Characterization of hepatocellular carcinoma developed after achieving sustained virological response to interferon therapy for hepatitis C. | Interferon (IFN) reduces the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis C (CHC). However, HCC develops in the some patients who have achieved a sustained virological response (SVR). The aim of this study was to clarify the features and prognosis of SVR patients who developed HCC. Twenty-s... | 18,985,618 |
Solid-state natural abundance 25Mg NMR studies of Na2MgEDTA x 4 H2O--a possible new reference compound for 25Mg NMR spectroscopy. | Natural abundance solid-state (25)Mg NMR measurements were made of the disodium salt of magnesium ethylenediaminetetraacetate tetrahydrate (Na(2)MgEDTA x 4 H(2)O). Both magic angle spinning (MAS) and static experiments were employed to determine the quadrupole coupling constant (C(q)) and the asymmetry parameter (eta(q... | 18,985,623 |
Tetramethyl-m-benziporphodimethene and isomeric alpha,beta-unsaturated gamma-lactam embedded N-confused tetramethyl-m-benziporphodimethenes. | The condensation reaction of alpha,alpha'-dihydroxy-1,3-diisopropylbenzene, pyrrole, and an aldehyde leads to the formation of tetramethyl-m-benziporphodimethene and outer alpha-pyrrolic carbon oxygenated N-confused tetramethyl-m-benziporphodimethenes containing a gamma-lactam ring in the macrocycle. Two isomers with t... | 18,985,649 |
Remodeling of fracture callus in mice is consistent with mechanical loading and bone remodeling theory. | During the remodeling phase of fracture healing in mice, the callus gradually transforms into a double cortex, which thereafter merges into one cortex. In large animals, a double cortex normally does not form. We investigated whether these patterns of remodeling of the fracture callus in mice can be explained by mechan... | 18,985,689 |
Nodal signaling promotes the speed and directional movement of cardiomyocytes in zebrafish. | Members of the Nodal family regulate left-right asymmetry during vertebrate organogenesis, but it is unclear how Nodal signaling controls asymmetric morphogenesis at the cellular level. We used high-resolution time-lapse imaging in zebrafish to compare the movements of cardiomyocytes in the presence or absence of Nodal... | 18,985,714 |
Phosphorylation of tropomyosin extends cooperative binding of myosin beyond a single regulatory unit. | Tropomyosin (Tm) is one of the major phosphoproteins comprising the thin filament of muscle. However, the specific role of Tm phosphorylation in modulating the mechanics of actomyosin interaction has not been determined. Here we show that Tm phosphorylation is necessary for long-range cooperative activation of myosin b... | 18,985,725 |
Reversal of iron-induced dilated cardiomyopathy during therapy with deferasirox in beta-thalassemia. | A 15-year-old male with beta-thalassemia major developed dilated cardiomyopathy secondary to iron-overload (Z-scores of left ventricle (LV) dimensions >3, ejection fraction (EF) 33%). Treatment with deferoxamine was unsuccessful, presumably due to poor compliance. After 15 months of using deferasirox (DFX), LV end-d... | 18,985,743 |
Aggressive and prosocial children's emotion attributions and moral reasoning. | Aggressive and prosocial children's emotion attributions and moral reasoning were investigated. Participants were 235 kindergarten children (M=6.2 years) and 136 elementary-school children (M=7.6 years) who were selected as aggressive or prosocial based on (kindergarten) teacher ratings. The children were asked to eval... | 18,985,747 |
Immobilization and controlled release of prostaglandin E2 from poly-L-lactide-co-glycolide microspheres. | Prostaglandin E(2) (PGE(2)) is an arachidonic acid metabolite involved in physiological homeostasis and numerous pathophysiological conditions. Furthermore, it has been demonstrated that prostaglandins have a stimulating effect not only on angiogenesis in situ and in vitro but also on chondrocyte proliferation in vitro... | 18,985,760 |
Nutritional management of newborn infants: practical guidelines. | The requirements of growth and organ development create a challenge in nutritional management of newborn infants, especially premature newborn and intestinal-failure infants. Since their feeding may increase the risk of necrotizing enterocolitis, some high-risk infants receive a small volume of feeding or parenteral nu... | 18,985,802 |
Inhibition of pancreatic carcinoma cell growth in vitro by DPC4 gene transfection. | To detect the expression of DPC4 in malignant and non-malignant specimens of human pancreas, and observe the inhibition of retroviral pLXSN containing DPC4 on pancreatic carcinoma cells in vitro. The expression of DPC4 was determined in 40 pancreatic adenocarcinoma and 36 non-malignant pancreatic specimens by reverse-t... | 18,985,820 |
Recurrent Mycoplasma pneumoniae infection in a human immunodeficiency virus-positive child. | Mycoplasma pneumoniae is a frequent cause of community-acquired respiratory infections, especially in young children and adolescents. The significance of M. pneumoniae infection in HIV-positive patients, particularly children, is not well described. This report describes an HIV-positive female child with recurrent B-ce... | 18,985,833 |
Republicans advocate change in the U.S. health care system including greater use of home and community-based care. | Senator John McCain is determined to implement changes to the U.S. health care system by making it more efficient and more responsive to consumers. Like the 50 state governors who on average see one fifth or more of their budgets taken up by Medicaid (their largest single expense), he has asserted that there is a crisi... | 18,985,874 |
Rapid effect of dexamethasone on the permeability of visceral sheep peritoneum. | The peritoneal mesothelium is a biologic barrier to water and ion transport. Its functional and structural integrity is crucial for peritoneal dialysis treatment. In vivo studies have shown that corticosteroids increase transcellular water transport and ultrafiltration of the rat peritoneum. In the present study, we us... | 18,985,993 |
Surgical techniques for prevention of recurrence after total enterolysis in encapsulating peritoneal sclerosis. | We performed total enterolysis in 130 patients with encapsulating peritoneal sclerosis (EPS) between 1993 and 2007. The postoperative survival rate was 93.1%. However, 33 of the patients (25.4%) required additional surgery for recurrent bowel obstruction. To prevent recurrent bowel obstruction, we investigated various ... | 18,986,001 |
Enrollment fluid status is independently associated with long-term survival of peritoneal dialysis patients. | Fluid overload is a common complication in peritoneal dialysis (PD) patients. The prognostic importance of enrollment fluid status in long-term PD patients remains to be investigated. The objective of the present study was to investigate the prognostic importance of enrollment fluid status in the long-term survival of ... | 18,986,007 |
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