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Epstein-Barr virus-associated thymidine kinase.
Superinfection of Raji cells with Epstein-Barr virus induced a new thymidine kinase that was distinguishable from both adult and fetal kinases of the host cell by discontinuous electrophoresis on polyacrylamide gels and glycerol gradients.
206,728
[ -0.167432, -0.1859036, -0.1667556, 0.007724365, 0.3388814, -0.305143, -0.3723513, -0.08246341, 0.05234681, -0.005368679, 0.1807353, 0.01911134, -0.1313731, 0.5023692, -0.3485554, -0.4185776, -0.3016135, -0.109409, -0.2128261, -0.00822951, 0.09686479, 0.282091, -0.1326491,...
[On the ACTH-corticoid relation in essential hypertension in dependence of plasma-renin activity (PRA) (author's transl)].
Patients with essential hypertension were studied for the reaction of the hypophyseal-adrenal-system before and during insulin hypoglycemia test. We found in our results that the mean total corticoid levels in plasma of hypertensive patients with low or high PRA are significantly higher than control levels. In insulin ...
206,764
[ -0.04785333, -0.1259783, -0.1086716, -0.01773372, 0.105033, -0.2275061, -0.2645222, 0.259232, 0.02040321, 0.1756018, 0.1380249, -0.02303314, -0.1235591, -0.1245867, -0.4628585, -0.02419354, -0.1095457, 0.3490957, 0.06723031, 0.3784553, 0.2782648, -0.1531768, 0.09157962, ...
[Effect of histones on a change in the enzymatic activity of Escherichia coli and Staphylococcus aureus cells].
Histones have been found to interfere with the permeability of the cellular membranes of Escherichia coli and Staphylococcus aureus, this resulting in the liberation of 14C-amino acids, the UV-absorbing endogenous material, and the products of RNA degradation. Histones, particularly arginine-rich fractions, stimulated ...
206,806
[ 0.1238078, -0.01581364, 0.1491714, 0.1743933, -0.1863828, -0.3871667, -0.2028344, 0.1324231, 0.3076071, 0.2295944, 0.08520809, 0.01259428, -0.138022, -0.0246154, -0.6253272, 0.05193538, -0.1391483, -0.04626326, -0.1154009, 0.2054843, 0.5154479, -0.04614935, -0.3632247, ...
Detection and kinetic behavior of preproinsulin in pancreatic islets.
Newly synthesized rat islet proteins have been analyzed by polyacrylamide slab gel electrophoresis and fluorography. A minor component having an apparent molecular weight of 11,100 was identified as preproinsulin by the sensitivity of its synthesis to glucose, the pattern of NH2-terminal leucine residues, and the rapid...
206,890
[ 0.07373632, -0.2148985, -0.4163043, -0.2682737, 0.2026923, -0.2942093, -0.07439155, 0.138434, 0.4146487, 0.2129379, 0.1327886, -0.1360386, 0.01487812, -0.2063362, -0.3146453, -0.04694064, -0.4058325, 0.1411369, 0.2409553, 0.150656, 0.3293446, 0.2394836, 0.06825344, 0.13...
Suckling behavior of the infant rat: modulation by a developing neurotransmitter system.
Drugs which alter serotonin receptor activity modified the suckling behavior of 20-day-old rat pups. Suckling could be reinstated in nondeprived pups, which normally do not suckle, by blockade of serotonin receptors with methysergide. Stimulation of serotonin receptors with quipazine inhibited suckling in deprived pup...
206,914
[ 0.0510395, -0.003654202, -0.251271, -0.2653831, 0.233064, -0.2668666, -0.2549825, -0.386948, -0.07634285, 0.01173846, 0.2028764, 0.2615565, -0.2049498, 0.130417, -0.2650067, 0.03430327, -0.632024, 0.1570151, -0.1193306, -0.03422238, 0.1290369, 0.2401988, 0.1088778, -0.3...
[Dynamics of temporary work incapacity and disability caused by tuberculosis in the Braşov district in the 1971-1976 period].
The paper stresses the fact that a decrease by approximately 50% was obtained, of the severity index due to tuberculosis, and by 63,6% of the incidence of invalidity through tuberculosis as a result of decreased morbidity and of the application of more efficient therapies over a shorter period of time. The prevalence o...
206,945
[ -0.0822951, -0.2068824, 0.4700849, 0.3358871, -0.1331363, -0.3791605, 0.04097762, -0.01071846, 0.02012903, -0.1675746, 0.1886224, -0.2619317, -0.1395493, 0.06362507, -0.2505995, -0.338082, -0.1665049, -0.2340554, -0.1648407, 0.2706164, -0.3597659, 0.04735368, -0.0971938, ...
Prevalence of antibodies to a rotavirus in black and white populations in South Africa.
A serological survey of antibodies to a rotavirus in 252 sera from Black and White South Africans was performed by means of an immunofluorescence test using cells infected with simian rotavirus, SA 11, as antigen. The results indicate widespread presence of this agent in South Africa and also that the Black population ...
206,980
[ 0.1015169, -0.2361563, 0.02256954, -0.01752033, -0.1869853, -0.02998155, -0.1346124, 0.09471167, 0.05674108, 0.101935, 0.2790597, 0.1828447, 0.1293596, 0.06766115, 0.03658903, -0.5559013, -0.4788155, 0.2475478, 0.09404019, 0.05308994, 0.2115999, 0.2858949, -0.1293544, -...
alpha 1-antitrypsin in cadmium toxicity: an evaluation of its suggested role.
Chowdhury and Louria [1] reported that cadmium could reduce in vitro the concentration and the trypsin inhibitory capacity of plasma alpha 1-antitrypsin. They suggested that this could explain the emphysema observed in some workers exposed to cadmium. Using the same experimental approach as these authors, we could not ...
206,988
[ -0.1889782, -0.3502568, -0.1330597, 0.1816085, -0.08723151, -0.1258137, -0.4229986, -0.1468909, -0.04237159, -0.1921997, 0.07333644, 0.1455938, 0.194157, -0.2037008, -0.2727079, 0.1758633, -0.3281037, -0.02839071, 0.1728884, -0.05665082, 0.3249263, 0.547429, -0.2329709, ...
[Lung metastases of a malignant giant cell tumour simulating an alveolar carcinosis (author's transl)].
A brief report an lung metastases of a malignant giant cell tumour simulating an alveolar cell carcinoma in peripheric regions is given, and a critical classification of alveolar cell carcinoma is supported.
207,045
[ -0.1972383, -0.2590743, -0.1182268, -0.1552652, 0.02093762, -0.1269625, -0.2912751, -0.07634351, -0.1127006, 0.1249055, 0.07250467, 0.05281417, 0.04642205, -0.0931485, -0.3814446, -0.1985626, -0.2972032, 0.2104183, 0.4580612, 0.03765838, 0.218067, 0.07564692, 0.102172, ...
[Significance of an oral cytogram for the characterization of synthetic sex steroids].
In this study we have found, that the gingiva epithelium is a sensitive hormonal receptor which may present different histologic and cytologic changes in relation to the hormonal influences acting upon this organ. The oral smears can be used as a reliable test for the evaluation of estrogenic effects in monohormonal co...
207,048
[ 0.09895668, -0.1753506, 0.0360404, 0.02636526, -0.04802488, -0.3408867, -0.1201838, -0.07611621, 0.1275948, -0.01595831, -0.01066547, 0.1526476, -0.01801593, 0.03209398, -0.8229078, -0.5221657, -0.2779235, 0.06661292, -0.04347543, 0.2003753, 0.5923913, 0.2804518, -0.15146...
[Use of the reversed passive hemagglutination in detection of Clostridium botulinum type A, B, and E toxin (author's transl)].
With the reversed passive hemagglutination technique it is possible to detect minimal amounts of botulinum type A, B and E toxins (s. Tab. 3). The antisera are used were prepared by foot--pad injection of rabbits with purified toxoids in Freund's complete adjuvant (s. Tab. 1). Antitoxin globulin were prepared from rabb...
207,051
[ -0.1028265, 0.0363416, -0.2818892, 0.2633472, -0.1211861, -0.3705876, -0.1026369, 0.318141, -0.223994, -0.1368122, 0.129026, 0.6211873, 0.28163, -0.03439699, -0.5035448, -0.126799, -0.3435638, -0.1745743, 0.1064925, 0.1681588, 0.3409561, 0.4264155, -0.2712066, -0.186270...
[Antiviral activity of tyrothricin against Sendai virus in suspension tests (author's transl)].
In suspension tests it could be found, that tyrothricin, isolated from bacteria, possesses an anti-infectious activity against Sendai virus. Concentrations of 10(2) to 10(3) ID50-units of Sendai virus were incubated with 0.5 and/or 1.0 mg tyrothricin per 5 ml for 30 minutes at 37 degrees C (pH 7.5). These mixtures were...
207,052
[ -0.04528544, -0.1360409, 0.07325058, 0.07556369, 0.1981849, -0.08859845, -0.2298514, -0.2751609, 0.2373442, -0.1394574, 0.0818474, -0.003577048, 0.02457562, 0.04526556, -0.5924041, -0.01690378, -0.4742168, 0.3846885, 0.01901907, 0.581668, 0.1085346, -0.05223005, 0.0085858...
[Opiate receptors and endogenous morphines: a new approach to the study of the brain].
The paper deals with a range of problems connected with a study of a nature and a function of specific neuronal receptors and endogenous morphines. It is demonstrated that a further development of studies in the given area will be of a principal significance in solving the cardinal problems of psychopharmacology and a ...
207,062
[ 0.02262214, 0.009838992, 0.02132006, 0.1621092, 0.07677786, -0.1222932, -0.304986, 0.0754853, -0.09593152, -0.08119246, 0.05524258, -0.1666712, 0.2510685, 0.04864873, -0.488397, -0.01829275, -0.3504633, 0.3600712, 0.1268075, 0.2651575, 0.2665834, 0.01207062, -0.1769529, ...
Regulation of phosphorylase-phosphatase from skeletal muscle by phosphorylation of a regulator protein.
The inhibitory effect of a heat-stable regulator protein from skeletal muscle on the activity of phosphorylase-phosphatase (EC 3.1.3.17) was studied. The regulator protein was shown to be both phosphorylated and dephosphorylated in vivo as well as in vitro. The incorporation of phosphate into the regulator protein incr...
207,067
[ -0.002356732, -0.1496357, -0.1870206, -0.21405, -0.2718076, -0.05085136, -0.1777699, 0.1603532, -0.04631696, -0.2589815, 0.1930956, 0.1794562, 0.1355658, -0.2008313, -0.7222595, -0.006733759, -0.5200962, -0.1511982, -0.0787781, 0.2853738, 0.1045452, 0.1781095, -0.06539362...
Excitatory effects of the electrical activity of muscle on the contiguous nerve.
Experiments were performed on frog sciatic-gastrocnemius preparations in order to investigate the different conditions under which the excitation can be transmitted from muscle to nerve. The results demonstrate that, on one hand, the proximal part of the m. gastrocnemius is of greater importance in the transmission of ...
207,068
[ -0.1022407, 0.03728024, -0.1847127, -0.06538396, -0.2024503, -0.2272368, -0.3370416, -0.09130687, -0.09071182, -0.04506286, -0.1426909, 0.04933127, 0.1431783, -0.1300058, -0.3438624, -0.2289585, -0.4930897, 0.0904984, -0.2512862, 0.04524183, 0.2535803, -0.005602952, 0.198...
Medullary arteries in cerebral neoplasms.
In cerebral neoplasms, the visibility of long segments of the medullary arteries indicates white matter involvement by infiltrative or compressive disturbances. Relating the mass effect to the position of the medullary arteries should allow for differentiating a primary from a secondary avascular neoplasm. When the neo...
207,096
[ -0.2573524, 0.1367108, -0.0555903, -0.3741863, 0.1364922, -0.2641213, 0.01683194, -0.1175552, -0.08329492, 0.2439965, 0.005230624, 0.2346876, -0.001960138, -0.1957617, -0.2057794, -0.1487577, -0.1466746, 0.07327987, 0.003138816, -0.04656815, 0.1828204, 0.1661753, 0.069698...
[Effect of fractionated pneumoencephalography on intracranial pressure].
The major changes in clinical condition during and after encephalography may be explained by intracranial pressure variations. If neither intracranial hypertension nor CSF dynamic perturbations exist, minimal complications may be predicted, but in intracranial hypertension immediate deterioration may occur. Despite an ...
207,116
[ -0.07694063, -0.08407696, -0.1532137, -0.1026487, 0.3318486, -0.2929841, -0.272075, -0.3798186, -0.01715782, 0.02868194, 0.1496661, 0.008020574, -0.2320143, 0.06942689, -0.2648779, -0.2280403, -0.142442, 0.1757595, -0.1188857, 0.1672127, -0.02195272, 0.07245935, 0.1171155...
Radiology of suprasellar ectopic pinealoma.
The radiographic and clinical findings in twenty-three recently reported cases of suprasellar ectopic pinealoma are reviewed and three previously unreported cases are described. It is concluded that suprasellar calcification is extremely rare; enlargement of the sella turcica was present in approximately 20 to 30 per c...
207,142
[ -0.1653485, 0.08106112, -0.2508433, -0.3089202, -0.1532915, -0.1357769, -0.3846323, -0.2184573, 0.2015468, 0.257134, 0.09638111, 0.1353808, -0.5808505, -0.09328572, -0.405756, -0.1175039, 0.001825599, 0.2112263, -0.08073869, -0.2081882, 0.1403901, 0.01195933, 0.08946902, ...
Accessory meningeal artery.
The accessory meningeal artery, originating from either the internal maxillary or middle meningeal artery, is predominantly an extracranial vessel. A minor branch of the artery enters the skull through the foramen ovale to supply the dura of the temporal fossa as well as the Gasserian ganglion. This intracranial branch...
207,149
[ -0.4596038, 0.1923108, -0.2692833, -0.3875, 0.1251643, -0.3781689, -0.2471221, -0.3046758, -0.1561444, 0.06415754, -0.02676091, 0.2052229, -0.04806356, -0.5127808, -0.5549098, 0.03686934, -0.3975147, 0.2202009, 0.126392, -0.2815046, 0.1586167, -0.003709735, 0.0209963, 0...
Radiologic evaluation of the function of the cervical spine.
Cervical functional examinations initiated in 1965 suggested the need of a correlated, multifactorial expression of the cervical sagittal movement function, allowing comparative evaluations of physiologic-diagnostic significance. Technical aspects of the successive steps of investigation, together with the final morpho...
207,150
[ -0.07588795, 0.09224728, -0.2459032, -0.05828563, -0.04589748, -0.5081887, -0.3380221, -0.09683093, 0.1442578, -0.01807938, -0.1178007, -0.2677041, -0.06937536, -0.2639807, -0.3016291, -0.1385186, -0.1387846, 0.02116092, -0.1712651, 0.1209082, 0.3373178, -0.04566526, -0.0...
Transient metabolic and vascular volume changes following rapid blood pressure alterations which precede the autoregulatory vasodilation of cerebrocortical vessels.
It has been shown by surface fluoro-reflectometry that stepwise decrease of arterial blood pressure causes a biphasic cerebrocortical vascular volume response. After the arterial blood pressure decrease the vascular volume first decreased and later increased. In both parts of the biphasic reflectance change, the cerebr...
207,169
[ -0.08009945, -0.0219281, -0.1805798, 0.04301212, -0.08481686, -0.5760871, 0.05865909, 0.07344043, 0.02103289, 0.0921448, 0.08865235, 0.1240259, 0.1451628, 0.01746647, -0.5381764, -0.06484117, -0.2928735, 0.1519569, 0.1062666, 0.2657518, 0.0712439, 0.0487357, -0.153701, ...
The public health significance of mycotoxins.
Diseases of man and animals associated with foodstuffs contaminated by molds have been known for centuries, but only recently have mycotoxicoses been recognized as a significant hazard to man. A detailed review of the literature involving the major mycotoxin-producing fungi is presented. Because of their hazards to bot...
207,207
[ -0.4195816, -0.4108101, -0.08103622, 0.02996707, 0.07951888, -0.1059173, -0.08128078, 0.1375297, -0.0372121, -0.1505547, 0.2305758, -0.2044805, 0.1467856, 0.0014384, -0.3064968, -0.1267024, -0.2796742, 0.1858231, 0.088916, -0.03167901, 0.1499888, 0.3644586, -0.1518836, ...
[Ultrastructure and clinicopathological aspects of mucoepidermoid tumour of the salivary glands (author's transl)].
The mucoepidermoid tumor of the salivary glands is relatively rare; its ultrastructure is analysed on the basis of four cases. Three secretory tumour cells can be differentiated: one tumour cell with mucous secretion and two tumour cells with abortive secretion which are different in structure. The dysregulated and abo...
207,234
[ -0.1874038, -0.2386388, -0.1602507, -0.1832948, -0.08341766, -0.4410392, -0.06506467, 0.05239692, 0.1928702, 0.3786953, 0.06688185, -0.1475925, -0.09745668, -0.08052971, -0.457133, 0.0002298006, -0.4111878, -0.1763999, -0.1419247, -0.06120394, 0.6545814, 0.278697, -0.1088...
Central retinal artery occlusion complicating Fabry's disease.
A 16-year-old boy had a central retinal artery occlusion and was subsequently diagnosed as a hemizygote with Fabry's disease. The typical ocular manifestations in males with this inborn error of glycosphingolipid metabolism include whorl-like corneal epithelial infiltrates, retinal and conjunctival vessel tortuosity, a...
207,248
[ 0.110271, 0.114505, -0.2409413, -0.008550268, 0.1002266, -0.2212611, -0.1051062, 0.1659579, -0.03482994, 0.2146519, 0.2150481, 0.386271, -0.4102931, 0.04509565, 0.1396458, 0.08546631, -0.4849307, -0.03690964, -0.03844869, -0.4321767, -0.1299923, 0.2324816, 0.01861982, 0...
The pathogenesis of infectious avian encephalomyelitis. 4. The effect of maternal antibody on the development of the disease.
Infectious avian encephalomyelitis virus (IAEV) maternal antibody was detected in the serum of chickens for up to 21 days following hatching. This antibody protected chickens against clinical IAE after intracerebral inoculation with van Roekel strain or oral administration of the NSW-1 strain of IAEV. Maternal antibody...
207,260
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Lack of protection against oxygen toxicity by in vivo protective agents in the isolated toad bladder.
Agents which protect against the development of oxygen toxicity in vivo were tested in an in vitro system, the isolated urinary bladder of the toad Bufo marinus. None of the agents protected against the inhibition of sodium transport across the bladder by hyperbaric oxygen exposure. Two protective agents, disulfiram an...
207,261
[ -0.4049099, 0.01261245, -0.159413, 0.3100116, -0.02378916, 0.008919008, -0.2303314, -0.0651283, -0.07944369, -0.3547989, 0.06393646, 0.2000191, 0.2911525, 0.05364399, -0.317009, -0.2236062, -0.1973612, 0.09710639, -0.1664843, 0.05125605, -0.1120685, 0.1610498, -0.1290628,...
Desensitization of the beta-adrenoceptor of lymphocytes from normal subjects and patients with phaeochromocytoma: studies in vivo.
1 Following the observation that lymphocyte beta-adrenoceptor responsiveness was not depressed in asthmatics treated only with non-adrenergic drugs we have explored the effects of prolonged exposure to beta-adrenoceptor agonists in normal subjects. 2 Treatment with oral salbutamol (12-16 mg/kg/day for 10 days), or with...
207,293
[ -0.3448697, -0.569626, -0.5306445, -0.4023336, 0.124262, -0.2992277, -0.2475805, 0.09501816, -0.01594283, 0.1554412, 0.2183509, -0.1845584, -0.03863866, 0.04614463, -0.3969812, -0.07139064, -0.2634194, 0.1461889, -0.1523399, 0.4632179, 0.2019888, -0.0208238, 0.05078705, ...
Solid tumour models for the assessment of different treatment modalities: VII: single vs fractionated doses of 5-fluorouracil on two solid tumours and their hosts.
The effects of one large single dose of 5-fluorouracil (FU) have been compared to the same amount given in divided doses daily over a 3- or 5-day period. Comparison of the effects of single vs fractionated dosage was made on 2 types of experimental solid tumour with different growth, cell kinetic, histological and meta...
207,298
[ -0.1627835, -0.136527, -0.2868071, -0.5699983, 0.2095038, -0.5301865, 0.3153148, 0.002794371, -0.1962192, -0.05138195, -0.2447098, 0.1368377, -0.2253368, 0.05634904, -0.7063156, -0.209943, 0.09114967, -0.05318764, -0.08742557, 0.4607427, 0.3063757, 0.2271447, -0.08060426,...
DNA unwinding protein from meiotic cells of Lilium.
An ATP-dependent DNA unwinding protein is present at a high level of activity in meiotic cells of lilies. The protein also acts as a DNA-dependent ATPase, the single strand form being the preferred cofactor. It binds in the absence of ATP to single-strand DNA and to ends or nicks in duplex DNA. A 3'-OH terminus is requ...
207,302
[ -0.1121357, -0.2530376, -0.1688305, -0.00154054, 0.2711704, -0.1613833, -0.1855607, -0.0607621, 0.334869, 0.007913046, 0.04449719, 0.5907593, 0.06979293, -0.1930244, -0.8910605, 0.05315588, -0.7531385, -0.2276133, -0.1811316, 0.09799581, 0.5634584, 0.2386799, -0.1498778, ...
Librational motion of an "immobilized" spin label: hemoglobin spin labeled by a maleimide derivative.
The spin label Tempo-maleimide, when "immobilized" in hemoglobin, is shown to exhibit motional fluctuation whose amplitude and/or frequency depend on temperature and solution conditions. These motional fluctuations are observable by several electron spin resonance techniques. For desalted hemoglobin the fluctuations ar...
207,310
[ -0.1456595, 0.4531282, -0.1689293, 0.04324592, 0.01323521, -0.2277592, -0.0606875, -0.202746, 0.07311013, -0.1434726, -0.0845461, -0.05126839, 0.2676719, 0.03030461, -0.2166602, 0.1898232, -0.6555883, -0.1324035, -0.2054127, -0.2830766, 0.118561, 0.04597906, 0.04111377, ...
Regulatory role of insulin in the degradation of low density lipoprotein by cultured human skin fibroblasts.
The degradation of 125I-labeled low density lipoprotein by cultured human skin fibroblasts was enhanced 25% by preincubation of cells with insulin. This effect of insulin appeared to be mediated via stimulation of low density lipoprotein binding to its cell surface receptor, since binding and subsequent internalization...
207,342
[ 0.07586963, -0.3512214, -0.0801584, -0.02220537, 0.06372043, -0.05373947, -0.2908829, 0.3941694, 0.0188784, 0.2055089, 0.2199189, -0.296135, 0.0112424, -0.171842, -0.328024, -0.2464151, -0.4095907, -0.2557237, -0.1305056, 0.3315827, 0.1079952, 0.5195922, -0.1013829, -0....
Specificity of the binding of trifluoperazine to the calcium-dependent activator of phosphodiesterase and to a series of other calcium-binding proteins.
Trifluoperazine inhibits the activation of phosphodiesterase by binding to the calcium-dependent activator. To determine further the specificity by which trifluoperazine binds to activator, we compared the binding of trifluoperazine to activator prepared from several species and tissues and to a number of other calcium...
207,350
[ 0.1000461, 0.03842243, -0.2507564, -0.2763801, 0.3491121, -0.05359671, -0.4134414, -0.0534554, 0.00808332, 0.02984058, -0.1151992, 0.3013471, -0.1712574, -0.0006324269, -0.3183116, 0.2305712, -0.6412577, -0.04562376, -0.19337, 0.4637525, 0.4300078, 0.01227357, -0.1720683,...
Dissociation of lutropin-induced loss of testicular lutropin receptors and lutropin-induced desensitization of testosterone synthesis.
The relationship between changes in testicular lutropin receptors, as measured by specific binding of 125I-labeled human chorionic gonadotropin, and testosterone synthesis in response to lutropin (testicular responsiveness) was studied in intact and hypophysectomized rats. Administration of a single 200-microgram dose ...
207,355
[ 0.389127, -0.162047, -0.3080688, -0.2479706, 0.061383, -0.3597521, -0.2074897, 0.1908984, 0.1190228, 0.1403282, 0.2345312, 0.1379011, -0.0001694417, -0.3706455, -0.08611287, -0.1912121, -0.4114093, -0.2444866, 0.02426202, -0.04333292, -0.02227232, 0.2437813, -0.09286728, ...
[Study of insulin receptors on liver and hepatoma cell plasma membranes].
Plasma membranes (PM) of helathy rats as well as those hepatomas and PM of tumor-bearing rats were found (radioreceptor assay) to have apparently two groups of receptors for insulin with a high and low affinity for the hormone respectively and different insulin-binding capacities. Kass values of the receptors with a hi...
207,360
[ 0.2175889, -0.414227, 0.09242196, -0.2490025, 0.2215, 0.02900778, -0.2455054, 0.4885789, 0.1851619, 0.06047926, 0.06191062, -0.07010899, 0.08039984, -0.2293472, -0.5477234, -0.1567292, -0.5377672, 0.1734415, 0.03226073, 0.1210399, 0.2697896, 0.1892713, 0.1143567, -0.058...
[Change in the concentration of nucleic acids and cAMP in neurogenic dystrophies of the stomach].
There proved to be a reduction of the RNA content in the tissue of the rat stomach in its dystrophic affection induced by traumatization of the duodenum, this pointing to the reconstruction of the cell genetic apparatus under conditions of extreme stimulation. Under the same experimental conditions there was a pronounc...
207,370
[ -0.07576825, -0.4158628, -0.07817046, -0.09886477, 0.1413956, -0.2239818, -0.2661929, 0.05268149, 0.1632309, 0.3387232, 0.1427937, -0.4328311, 0.1013977, -0.04379386, -0.2913588, -0.03311761, -0.2084994, -0.2838078, -0.06967763, 0.2540013, 0.4702475, 0.08660231, -0.050293...
Efficacy of laboratory tests for the detection of enterotoxigenic Clostridium perfringens.
Nineteen Clostridium perfringens strains with positive erythemal and ligated intestinal loop reactions, and 22 strains with negative reactions, originating from food-poisoning cases, were tested comparatively using the fluorescent antibody (FA), reversed passive hemagglutination (RPHA), and immunodiffusion (ID) tests. ...
207,403
[ 0.05041238, -0.5164769, -0.06277583, -0.1316329, 0.2051511, -0.02764265, -0.01034393, 0.4272783, -0.06745458, -0.1275816, 0.2844125, 0.5664337, 0.030146, 0.2114413, -0.3757511, 0.07718766, -0.6121368, 0.1540162, 0.01196316, 0.01149445, 0.4381295, 0.324073, -0.0871665, -...
Identification of a transformation-specific protein induced by a Rous sarcoma virus.
Using antisera obtained from rats bearing Schmidt-Ruppin strain Rous sarcoma virus-induced tumors, we have idnetified a protein with an apparent molecular weight of 56,000 daltons and an isoelectric point of 6.3 in extracts of chick embryo fibroblasts transformed by a wild-type nondefective Rous sarcoma virus (Schmidt-...
207,435
[ -0.05939782, -0.184712, -0.3364913, -0.1731738, 0.2566079, -0.3618729, -0.002604416, 0.03649538, 0.2525987, 0.3011862, 0.1245138, -0.07817865, -0.2466191, -0.1722496, -0.1769863, 0.03364309, 0.05958442, -0.3182393, 0.0138238, 0.3351725, 0.05200674, 0.05305232, -0.2152276,...
Synthesis and infectivity of vesicular stomatitis virus containing nonglycosylated G protein.
The replication of vesicular stomatitis virus (VSV) is inhibited by tunicamycin (TM), an antibiotic that blocks the formation of N-acetylglucosaminelipid intermediates. We had shown previously that the viral glycoprotein (G) synthesized in cells treated with TM is not glycosylated and is not found on the outer surface ...
207,437
[ -0.07186989, -0.1488874, -0.3106785, -0.2151421, 0.1935642, 0.2172725, 0.03128042, 0.1592743, 0.1467008, 0.03442902, 0.06471285, 0.02211106, -0.2167577, 0.0122467, -0.2328591, 0.0315305, -0.4626151, -0.1927491, -0.01927049, 0.1331288, 0.3490225, 0.06028234, -0.2060342, ...
Enzymic determination of cholesterol in serum lipoproteins separated by electrophoresis.
We describe a reliable, straightforward procedure for measuring the cholesterol content of serum lipoproteins separated by electrophoresis on cellulose acetate. The lipoprotein fractions are made visible by use of an enzymic reagent and then quantitated by densitometry. Standard electrophoresis equipment is used and th...
207,466
[ 0.1467027, 0.2459645, -0.2867478, -0.271016, 0.01602269, -0.04169215, -0.1711969, 0.2724551, 0.202792, 0.1194578, 0.1497486, 0.04858181, 0.08558021, 0.07075168, -0.3885366, -0.0238796, -0.5106872, -0.01379161, 0.01423176, 0.3677921, 0.2185791, 0.08771457, -0.126952, 0.0...
Modification of lymphocyte responsiveness in vitro by lambda carrageenan compared with colloidal silica and depletion of surface adherent cells.
The effects of the immunosuppressive sulphated polygalactan lambda carrageenan on in vitro models of allograft immunity were compared with the effects of removing macrophages (surface adherent and/or phagocytic cells) by established methods. Carrageenan depressed the primary mixed lymphocyte reactions, but not to the s...
207,475
[ 0.1406558, 0.08716231, -0.07436078, 0.2336704, 0.2935535, -0.1223201, -0.1454383, 0.07981397, 0.3557702, 0.2109443, 0.02120372, 0.1169024, 0.2510199, -0.0762091, -0.1785465, 0.09594087, -0.4449279, -0.008969497, 0.1290778, 0.2316923, -0.02724496, 0.1771113, 0.01489649, ...
Porphyria cutanea tarda. A rare cutaneous manifestation of hepatic tumors.
Porphyria cutanea tarda (PCT), the most common form of porphyria, may be one of the rare cutaneous manifestations of hepatic tumors, benign, malignant, or metastatic. The liver damage associated with PCT may predispose to the development of hepatocellular carcinoma. Our experience and a review of the literature suggest...
207,491
[ -0.180329, -0.4600512, -0.1404224, -0.07922996, 0.06438196, -0.1219717, -0.4009237, -0.1901145, 0.04417012, 0.3189851, -0.04877905, -0.08881196, -0.05457084, -0.1571873, -0.284887, -0.08197334, -0.218329, 0.08163283, 0.2190612, -0.02570557, -0.02003349, 0.04754594, -0.185...
Amino acid transport in isolated hepatocytes: effect of glucagon.
Amino acid transport was studied in freshly isolated adult rat hepatocytes using non-metabolizable alpha-amino-1-[14C] isobutyric acid and 1-aminocyclopentane-1-[14C] carboxylic acid. In the presence of sodium, hepatocytes concentrated alpha-aminoisobutyric acid; this concentrative component of the transport had proper...
207,495
[ -0.2888387, -0.2906403, -0.2932859, 0.09459739, 0.2610434, -0.1876447, -0.3661888, 0.1023785, 0.02046357, 0.1421676, -0.05373069, -0.06982937, 0.01318178, 0.143244, -0.1017339, -0.1542917, -0.4198691, 0.1972856, -0.1392292, -0.09670674, 0.1922414, 0.1173055, -0.01541422, ...
Shedding of anti-IgM from antibody-coated human lymphoma lines: differences between Epstein-Barr virus-negative lines and their virus-converted sublines.
In vitro converted, Epstein-Barr (EBV) genome-carrying cell lines showed a reduced ability to shed surface-bound antibodies, compared to their EBV-free parental B lymphoma lines. On the other hand, antibody degradation was higher with EBV-positive cells. Analysis of antibody-coated single cells revealed that cells whic...
207,534
[ -0.03312653, -0.01056701, -0.1068813, -0.3933221, -0.02537954, -0.1094396, -0.1711691, 0.1481369, 0.09016702, 0.4990628, 0.2131334, 0.009991895, 0.1519735, 0.158629, -0.2862412, 0.06964412, -0.422916, 0.01705624, 0.02723696, 0.2506353, 0.329469, -0.1404373, -0.1265147, ...
[Clinial picture and localization of skin metastasis of visceral carcinomas].
Seven cases with secondary skin carcinomas are described. The primary tumor was located at the tongue, the larynx, the thyroid, the abdomen, the ovaries, the collum uteri and the rectum. From the literature 60 other patients with secundary skin carcinomas and 100 primary carcinomas were evaluated. Clinical evidences fo...
207,659
[ 0.1933609, -0.2158325, -0.117975, -0.1510964, 0.08356003, -0.2632999, -0.4041947, -0.4659193, -0.08456299, 0.352193, 0.2539305, 0.3102489, 0.01872987, -0.3161166, 0.04908691, -0.06601764, -0.3323731, 0.0773164, 0.3197752, -0.1274886, 0.4145436, 0.4635553, -0.2123061, 0....
Citrobacter O-antigens: structure of the O-antigenic polysaccharide from Citrobacter sp. 396.
The structure of the O-specific polysaccharide moiety of the lipopolysaccharide from Citrobacter 396 was elucidated by composition, methylation, and periodate oxidation studies. The repeating unit consists of four 2-linked mannoses and one 3-linked N-acetylglucosamine. One of the mannose units is substituted at C3 with...
207,667
[ -0.06270304, 0.01376135, -0.1600918, 0.08866811, -0.2397432, -0.1052416, -0.1084321, 0.1488888, 0.07621899, -0.2218303, -0.04720296, -0.08280325, -0.0118045, -0.1924334, -0.07813532, 0.1797566, -0.8589141, 0.1975609, 0.1268662, 0.1184529, 0.2500787, -0.006280407, -0.18038...
Outgrowth and vegetative growth inhibition of Bacillus subtilis spores after transient exposure to polymyxin B.
Polymyxin B combined with the resting spores of Bacillus subtilis and inhibited outgrowth and vegetative growth after germination. The antibiotic was released from the resting spores and its inhibitory action was reversed by the addition of di- and trivalent metallic cations.
207,673
[ -0.1404712, -0.1378009, -0.2773825, 0.05863112, -0.07553893, -0.2710157, -0.1795043, 0.05366149, -0.2044817, -0.1421398, 0.05729386, 0.2972296, -0.1673775, 0.1153196, -0.483924, 0.1477888, -0.06773823, 0.04448244, -0.1591412, 0.1553127, 0.4655045, 0.2497997, 0.06607886, ...
Identification of cytochrome c oxidase subunits in nuclear yeast mutants lacking the functional enzyme.
Yeast mutants specifically lacking cytochrome c oxidase activity were screened for cytochrome c oxidase subunits by one- and two-dimensional electrophoresis, electrophoresis in exponential gradient gels, and immunoprecipitation with antisera against one or more of the cytoplasmically made subunits of the enzyme. Two cy...
207,698
[ 0.04189675, 0.0230778, -0.09011725, 0.01563185, 0.1370921, 0.0352921, -0.07795414, 0.02570685, 0.2807652, 0.004042603, 0.0672484, -0.146866, -0.2294954, 0.0681916, -0.3004762, 0.480667, -0.5387192, -0.06603906, -0.01222362, -0.2225661, 0.3862149, 0.1542362, -0.005194761, ...
Quantitative correlation between simian virus 40 T-antigen synthesis and late viral gene expression in permissive and nonpermissive cells.
The time-course of intranuclear Simian virus 40 (SV40) tumor (T) antigen synthesis and accumulation in permissive CV1 monkey cells and nonpermissive 3T3 mouse cells has been studied by immunofluorescence and cytofluorometry. CV1 cells accumulate T antigen continuously over a period of 48 h after infection, whereas in 3...
207,711
[ -0.1425139, -0.3515753, -0.4590095, -0.1656135, 0.1997641, -0.3436674, -0.2037929, 0.1984832, 0.2196726, 0.1772814, 0.112019, -0.1340268, -0.08879247, -0.07618234, -0.297409, -0.3574045, -0.1544645, -0.119776, 0.06036302, 0.3091726, 0.3157485, 0.198181, -0.1355101, -0.0...
High-performance liquid chromatography determination of potential content of vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol) in resins, oils, dry concentrates and multivitamin formulations.
The determination of potential vitamin D concentrations in raw materials and in multivitamin formulations by high-performance liquid chromatography is reported. Simple experimental conditions allow the rapid separation of the vitamins from their respective pro- and pre-vitamins, from their irradiation side-products and...
207,716
[ -0.4241024, 0.288853, 0.03052836, 0.04062968, 0.3602853, -0.3151366, -0.06169866, -0.04106578, 0.2868544, -0.05695684, 0.3191555, 0.03990748, 0.03497732, -0.1128474, -0.5015106, -0.2204858, -0.1030795, -0.161451, -0.1003955, 0.3041064, 0.2505159, 0.3581551, -0.3106128, ...
Chemiluminescence of human and canine polymorphonuclear leukocytes in the absence of phagocytosis.
Polymorphonuclear leukocytes (PMNs) have increased oxidative metabolism during phagocytosis and emit light (chemiluminescence, CL) as a result of metabolic activation. The present study examined PMN CL in the absence of phagocytosis using sodium fluoride (NaF), a nonparticulate agent and known stimulator of cellular ox...
207,727
[ 0.06641183, 0.1314904, 0.04113493, -0.04153718, -0.1153694, -0.3085005, -0.2535278, 0.2196067, -0.06308501, 0.02104402, -0.2232293, 0.04892302, 0.08942136, -0.08426335, -0.1595084, -0.1702538, -0.5270305, 0.08145554, 0.06760619, 0.3670732, 0.07051442, 0.09172034, -0.01198...
Interacting effects of sulfonylureas and glucose on cyclic AMP metabolism and insulin release in pancreatic islets of the rat.
The effects of tolbutamide and glibenclamide on the metabolism of cyclic AMP were investigated in pancreatic islets of the rat. Changes in cyclic AMP were assessed by measuring [(3)H]cyclic AMP after labeling of the islets with [2-(3)H]adenine. In the presence of a nonstimulatory concentration of glucose (3.3 mM), both...
207,736
[ -0.1584733, -0.1929968, -0.3079948, 0.0001385054, 0.1272074, -0.1195959, -0.00004046899, 0.4919901, 0.001867913, 0.04244621, -0.08222281, -0.1101767, -0.2239502, 0.2235878, -0.4429972, 0.05262412, -0.5937267, 0.2346855, -0.2650276, 0.320335, 0.5689413, 0.1883472, 0.069241...
Effects of dietary polyunsaturated and saturated fat on the properties of high density lipoproteins and the metabolism of apolipoprotein A-I.
In this study we have investigated, in four normal males the effects of dietary saturated and polyunsaturated fat on the chemical composition and thermotropic properties of human high density lipoproteins (HDL) and have measured the influence of the diets on the metabolism of that fraction of HDL apolipoprotein A-I (ap...
207,739
[ 0.01611678, 0.1994748, -0.4043694, 0.03886681, 0.066397, 0.03722877, -0.04461715, 0.3803126, 0.2088219, -0.1292794, -0.03782555, -0.07954234, 0.2280362, -0.1987827, -0.3801883, -0.1808735, -0.4946087, -0.0831821, -0.0483043, 0.1502518, 0.1646134, 0.4317049, 0.1658901, 0...
Endogenous GTP and the regulation of epinephrine stimulation of adenylate cyclase.
Epinephrine increased adenylate cyclase activity 10 to 15 fold in lysates of the cultured human astrocytoma cell line 132-1N1. GTP had little effect on adenylate cyclase activity of lysed cell preparations either with or without added epinephrine. However, the epinephrine stimulation of adenylate cyclase was essentiall...
207,754
[ -0.1980248, 0.07025534, -0.6786171, -0.3526736, 0.04443791, -0.3116937, -0.454965, 0.02533488, 0.3820706, 0.1616647, -0.2050166, -0.03735376, -0.114982, 0.2145222, -0.5934896, 0.01351143, -0.5005334, -0.03133423, -0.1278846, 0.06475388, 0.4688269, -0.1854573, -0.0105076, ...
Flow microfluorometric analysis of herpesvirus infected BHK-21 and BALB/3T3 cell cultures.
The interaction of herpes simplex type 1 with two eukaryotic cell lines (BHK-21 and BALB/3T3) was investigated by flow microfluorometric analysis after cell staining with mithramycin. Uninfected, lytically infected and persistently infected cell populations were examined. Viral replication within an infected cell popul...
207,772
[ -0.2425657, -0.3179758, -0.2259589, 0.1467429, 0.3583649, -0.1924073, -0.1249555, 0.2007336, 0.09977396, -0.172716, 0.169533, -0.2776213, -0.3580038, 0.04045082, -0.3994157, -0.02493487, 0.09477629, 0.3381882, -0.3096489, 0.1909979, 0.5459285, -0.2173917, -0.03098507, -...
Assessment of cell-mediated hypersensitivity against coxsackievirus B3 viral-induced myocarditis utilizing hypertonic salt extracts of cardiac tissue.
Hypertonic KCl extracts prepared from heart tissues of adolescent CD-1 mice inoculated with coxsackievirus B3 (CVB3) were tested for antigenicity in evaluating cell-mediated sensitivity to CVB3 virus utilizing the agarose droplet cell-migration-inhibition assay. Immune mouse peritoneal exudate cells (IMPEC) from mice i...
207,775
[ -0.2341456, -0.2291128, -0.5387395, -0.1944772, 0.02037677, -0.1247725, -0.3060983, 0.2089164, -0.1856583, -0.2814654, -0.2143969, -0.008887455, 0.1980294, -0.004187265, -0.09975931, 0.05090797, -0.3820558, -0.0882628, -0.4458346, 0.2873974, 0.2140188, 0.01607318, -0.3874...
Demonstration of a surface antigen on Epstein-Barr virus genome-carrying lymphoid cells: distinction from the virus-determined membrane antigen.
A surface antigen (SA) was detected on Epstein-Barr virus (EBV)-carrying lymphoid cell lines by indirect membrane immunofluorescence with an antiserum from a rabbit immunized with Raji cells; the antiserum had been extensively absorbed with normal human blood and tonsil cells. The SA was not detected on normal human um...
207,776
[ 0.03871204, -0.3621128, -0.02848953, -0.02890395, 0.2841371, -0.09424624, -0.3264888, 0.04583015, 0.1460102, 0.278793, 0.2393375, -0.04811541, 0.2233213, 0.1043521, -0.5830675, -0.3301693, -0.601076, 0.1410802, -0.2143478, -0.02386181, 0.4067762, 0.02359605, -0.1325751, ...
Spin membrane immunoassay: simplicity and specificity.
The many disadvantages of radioimmunoassay (RIA) have stimulated attempts to develop non-radioactive assays. These include spin immunoassay (SIA), which is simple, specific, and requires no separation procedures but is much less sensitive than RIA. The membrane immunoassay (MIA) described here is more sensitive than th...
207,779
[ 0.2468682, -0.3401194, 0.1046488, -0.2060661, -0.07037945, 0.3275952, -0.08342452, 0.09597209, 0.3055009, 0.01352805, -0.2170421, 0.3641827, 0.1683149, 0.01235239, -0.4220597, -0.179007, -0.7555061, 0.2513931, -0.169103, 0.06878222, 0.2802918, -0.3861669, -0.1151175, -0...
Granular cell myoblastoma of the larynx.
Two cases of granular cell myoblastoma of the larynx are presented. In the first case the tumour was excised by laryngofissure, and in the second case by microlaryngoscopy. Based on this experience a review of this interesting tumour is made, and emphasis is given to the fact that this neoplasm may be mistaken for squa...
207,798
[ -0.3581048, -0.1714635, -0.2714889, -0.3351919, 0.0261092, -0.1075788, -0.2923049, -0.300202, -0.01754208, 0.2021692, 0.3569472, 0.2418615, -0.1727878, -0.3853159, -0.04274627, 0.1028063, -0.1420404, 0.1017673, -0.1920715, -0.1630353, 0.6826998, 0.06801216, 0.04533487, ...
Proteolytic digestion in the elucidation of the structure of low density lipoprotein.
The apoprotein (apoB) of low density lipoprotein (LDL) is reported to be a large polypeptide, and it is proposed that there are two similar-sized subunit proteins in LDL (Smith, Dawson, and Tanford. 1972. J. Biol. Chem. 247: 3376-3381.). When apoB is isolated under conditions that minimize artifactual proteolysis, only...
207,802
[ -0.1050519, 0.2262522, -0.2133446, -0.1788725, 0.1868474, -0.2698475, -0.08433804, 0.1714268, 0.4923199, 0.1669884, 0.04270858, 0.1224136, -0.07739612, -0.1269313, -0.3254141, 0.1175154, -0.4254003, -0.1042138, 0.2228005, 0.183257, -0.07137016, 0.3679745, -0.1335285, 0....
Studies on the replication of KRV single-stranded linear DNA.
The autonomous parvovirus, Kilham rat virus (KRV), is composed of three structural proteins (Salzman & White, 1970) and a single molecule of DNA. The DNA molecule is linear and single-stranded (ss). It is believed to have both 3' and 5'-terminal palindromic sequences (Salzman, 1977). Replication of the ss DNA may i...
207,822
[ -0.3141127, -0.06173022, -0.159682, -0.2018696, 0.4682299, -0.3425135, -0.4185718, -0.0337978, 0.3437284, 0.1948531, 0.0439149, 0.2794563, -0.02713593, 0.2328848, -0.05248357, -0.0986241, -0.5798132, -0.1326949, 0.04795868, -0.2962524, 0.234784, -0.06641681, -0.2743979, ...
Fast-neutron irradiation of glioblastoma multiforme. Neuropathological analysis.
Various modes of therapy, alone or in combination, have had little effect in improving the survival of patients with glioblastoma multiforme. Recently, in a pilot study, 34 patients with glioblastoma were treated by fast-neutron-beam irradiation of the whole brain. Following treatment, the patients became steroid-depen...
207,833
[ -0.1308019, 0.2684037, 0.07708077, -0.09952705, -0.2184419, -0.6059953, -0.125883, 0.1111179, -0.09117541, 0.2665541, -0.2071463, 0.1222476, 0.04466499, 0.2355948, -0.21945, -0.1522354, 0.2208162, -0.006328844, 0.1831705, 0.0006384309, 0.374983, 0.4007584, -0.08868921, ...
Polydipsia, polyuria, and hypertension associated with renin-secreting Wilms tumor.
A 16-month-old black male infant had unusual thirst, polyuria, hyponatremia, and hypertension. His polyuria was unresponsive to vasopressin therapy, and his high blood pressure was not effectively controlled by antihypertensive drugs. Radiographic examinations revealed an occult Wilms tumor in the right kidney. After r...
207,843
[ -0.291838, 0.01986096, -0.2362844, -0.2954603, 0.1263371, -0.3825249, -0.1130029, -0.1033995, 0.2247399, 0.133514, 0.235553, 0.582082, -0.3248188, -0.08074529, -0.4255415, -0.0118519, -0.1059694, 0.03171328, 0.3630946, -0.3264866, 0.2969661, 0.2037038, -0.2969573, 0.110...
Microviscosity of mucosal cellular membranes in toad urinary bladder: relation to antidiuretic hormone action on water permeability.
The microviscosity of cellular membranes (or membrane fluidity) was measured in suspensions of single mucosal cells isolated from the urinary bladder of the toad, Bufo marinus, by the technique of polarized fluorescence emission spectroscopy utilizing the hydrophobic fluorescent probe, perylene. At 23 degrees C, 5 mM d...
207,870
[ -0.2073064, -0.1672707, -0.2467169, -0.07022348, 0.238356, -0.115727, 0.01263624, 0.3385746, 0.2773642, 0.1153373, 0.06007873, -0.06116682, -0.1355906, 0.08042693, -0.118526, -0.1911697, -0.28773, 0.2045027, -0.3923123, 0.2631869, 0.5194044, 0.1601533, 0.07707939, 0.379...
Evidence for involvement of microtubules in the action of vasopressin in toad urinary bladder. I. Functional studies on the effects of antimitotic agents on the response to vasopressin.
The antimitotic agents colchicine, podophyllotoxin, and vinblastine inhibit the action of vasopressin and cyclic AMP on osmotic water movement in the toad urinary bladder. The alkaloids have no effect on either basal or vasopressin-stimulated sodium transport or urea flux across the tissue. Inhibition of vasopressin-in...
207,871
[ -0.3206496, 0.007613218, -0.5180382, -0.1123108, 0.2742178, -0.2340509, -0.05369323, -0.004176726, -0.05443338, 0.1001902, 0.07504345, 0.03619763, 0.02899714, 0.1700783, -0.3370929, -0.16222, -0.4013104, 0.1028003, -0.2460661, 0.0315398, 0.5067616, 0.1491656, 0.01265926, ...
Presence of 5'-terminal cap structures in virus-specific RNA from feline leukemia virus-infected cells.
The F-422 line of feline thymus tumor cells, chronically infected with the Rickard strain of feline leukemia virus (R-FeLV), was labeled with 32P, and the total cytoplasmic RNA was isolated. The RNA was centrifuged through sucrose gradients, and R-FeLV virus-specific RNA (vRNA) was located by hybridization of portions ...
207,884
[ -0.4840969, -0.004166939, -0.07051814, -0.4112445, 0.06300385, -0.1558982, -0.4648197, -0.04394184, -0.07385648, 0.3749539, 0.09347992, -0.05787395, -0.2553541, 0.2420296, -0.4669065, 0.2294021, -0.2487955, -0.2146969, 0.06490042, 0.2144893, 0.1967262, -0.06550333, -0.225...
Purification and characterization of varicella-zoster virus-induced DNA polymerase.
Infection of WI-38 human fibroblasts with varicella-zoster virus led to the stimulation of host cell DNA polymerase synthesis and induction of a new virus-specific DNA polymerase. This virus-induced DNA polymerase was partially purified and separated from host cell enzymes by DEAE-cellulose and phosphocellulose column ...
207,886
[ -0.2002202, -0.08521905, -0.2555782, 0.08335256, 0.4503344, -0.3129911, -0.4537265, 0.2009039, -0.06270293, 0.01046695, -0.100121, -0.04509991, 0.04173702, -0.02161914, -0.5572214, -0.01712305, -0.1101652, 0.3960511, 0.2387401, 0.5072893, 0.5981121, 0.06989878, -0.5276834...
Rescue of endogenous 30S retroviral sequences from mouse cells by baboon type C virus.
Mus musculus SC-1 cells were infected with M7 baboon type C virus. The progeny of this infection included viral pseudotypes that contained M7 helper virus and endogenous 30S retrovirus-associated sequences derived from SC-1 cells (RAS). The RAS sequences are unrelated by nucleic acid hybridization criteria to previousl...
207,887
[ -0.1004421, 0.3345571, -0.3456493, -0.4334215, 0.3948779, -0.2449373, -0.399987, -0.2054475, 0.2408696, -0.2180061, 0.06831304, 0.1955254, -0.03977223, 0.4512189, -0.3337429, -0.3435992, -0.1709744, -0.3206695, 0.2804046, -0.1223335, 0.3212483, 0.1038593, -0.09075656, -...
Bone infections involving anaerobic bacteria.
Over 700 cases of anaerobic osteomyelitis have been reported in the literature. Nonetheless, most reviews of osteomyelitis have paid little attention to the potential role of anaerobes in bone infections. There have, as yet, been no prospective studies of osteomyelitis utlizing optimal anaerobic transport and culture t...
207,946
[ -0.2549381, -0.4196434, -0.03656325, -0.01293292, -0.1423862, -0.4566036, -0.2723805, 0.1368523, -0.02947114, -0.2798009, -0.1548643, -0.07615598, 0.01485044, 0.05514176, -0.08814681, -0.09880826, -0.1650676, 0.04054476, -0.4091662, 0.1719446, -0.01307899, 0.02844968, 0.2...
[Intestinal yersiniosis: 25 cases of infections with Yersinia pseudotuberculosis and Yersinia enterocolitica (author's transl)].
Yersinia infections in 16 adults and 9 children are reported. 15 cases were caused by Yersinia pseudotuberculosis, 8 of them were proved by serological findings. In 4 cases the infection by Yersinia pseudotuberculosis was likely, in 3 other cases possible only. Real infections caused by serotype IV are demonstrated too...
207,960
[ 0.1189483, -0.04142641, -0.04542264, -0.3143125, 0.1243072, -0.171515, -0.009064599, 0.188356, -0.4147959, -0.2827482, 0.1474614, 0.167383, 0.3327112, -0.259639, -0.7486171, -0.360297, -0.3241437, 0.3439147, 0.1024317, 0.1587907, 0.2792972, -0.003484669, -0.1988678, 0.0...
Argentine hemorrhagic fever. Alterations of the complement system and anti-Junin-virus humoral response.
We investigated immunologic mechanisms and the role of complement in the pathogenesis of Argentine hemorrhagic fever, a disease caused by the Junin virus, a member of the arenavirus group. Total serum complement activity was reduced to 68 per cent of control values in patients with severe or moderate disease (P less th...
207,985
[ 0.07321161, 0.008960623, 0.1260629, 0.0623366, -0.09630115, 0.1330555, 0.0289278, 0.1102344, 0.08577894, 0.1293546, 0.04374089, -0.3669516, 0.1920695, -0.2226626, -0.4187894, -0.5353401, 0.2165195, -0.05435935, 0.2995386, 0.3656894, 0.01798611, -0.04132799, -0.3341293, ...
[Whited Addison's disease. Eight cases (author's transl)].
In 8 cases of Addison's disease due to adrenal tuberculosis, the substitutive treatment appeared unnecessary since more than one year. Urinary 17-OHCS were in the normal range but did not rise after ACTH injection except in two cases. In all the cases, plasma ACTH was elevated but lower than in severe adrenal insuffici...
208,057
[ -0.3044944, -0.01741434, -0.3095966, -0.04699273, 0.05331809, -0.3014674, -0.5144404, 0.1725883, 0.178448, 0.02757568, 0.1282398, 0.1290383, -0.03610237, 0.1233081, -0.3134922, -0.2045599, -0.07310674, -0.1682806, 0.0223202, 0.02159454, 0.3746419, 0.09715395, -0.1318128, ...
beta-Lipotropin is the major opioid-like peptide of human pituitary and rat pars distalis: lack of significant beta-endorphin.
beta-Lipotropin is the predominant opioid peptide of the human pituitary and rat pars distalis and is present in concentrations essentially equimolar with corticotropin. When freshly, obtained nonfrozen rat anterior pituitaries were homogenized with 0.2 M HCl, approximately 98% of the immunoreactivity detected utilizin...
208,078
[ 0.1270383, -0.08267445, -0.3164879, 0.1184337, 0.1864918, -0.3004349, -0.2640676, 0.1783726, 0.2548271, 0.1725927, 0.05463628, 0.1048385, 0.2184622, -0.2853678, 0.05739312, -0.14986, -0.1805055, -0.0509328, 0.4467709, 0.04438383, -0.05646559, -0.01174846, -0.2414584, -0...
Ultrastructural localization of gamma-aminobutyric acid receptors in the mammalian central nervous system by means of [3H]muscimol binding.
This study utilizes tritiated muscimol binding and electron microscope autoradiography (Ilford L4 emulsion and phenidone development) to localize gamma-aminobutyric acid (GABA) receptor sites in the cerebellum of the rat. In the cerebellar cortex, silver grains were associated with somata and dendrites of basket and st...
208,082
[ 0.2913885, -0.1243309, 0.03246781, -0.11712, 0.6134661, -0.3283125, -0.6180223, -0.2467972, -0.05059753, -0.06399865, -0.1775644, 0.2412334, 0.043421, 0.1256385, 0.01985279, 0.1610889, -0.3778102, 0.2466357, 0.05457227, 0.0288851, 0.5513585, 0.2976581, 0.0302214, -0.132...
Influence of bile acids and free fatty acids on physicochemical properties of LP-X.
In this study it is demonstrated, that incubation of both, bile acids and free fatty acids with LP-X, the abnormal plasmalipoprotein found in patients suffering from cholestasis or LCAT-deficiency, results in striking alterations of the physico-chemical and immunological properties of LP-X: 1. The cathodic mobility in ...
208,127
[ 0.1014792, 0.06565174, -0.08674672, -0.04035069, 0.2334857, -0.1656691, -0.3831148, 0.1638835, 0.02672416, -0.06935812, 0.1941157, -0.09521641, 0.1905169, 0.3314864, -0.1732798, 0.3603022, -0.2815442, 0.0449466, -0.07748784, 0.1496826, 0.3225144, 0.1803697, -0.1172564, ...
[Primary hyperparthyroidism. Analysis of 152 patients with special reference to acute life threatening complications (acute hyperparathyroidism)].
The findings of 152 patients with proven primary hyperparathyroidism are reportedmthe purpose of the analysis was to find difference between the various clinical manifestations of the disease. Furthermore the occurrence of acute hyperparathyroid crisis in our series as well as in the literature are described. 65.8% of ...
208,139
[ -0.2047286, -0.3645475, -0.06006906, -0.2627246, 0.0919916, -0.5983129, -0.1964734, -0.07353202, 0.1395856, 0.1337664, 0.01218877, -0.1743091, -0.07555939, -0.2830001, -0.4375081, -0.1054807, -0.02635592, 0.06329403, 0.1015999, 0.4275343, 0.2210106, 0.2785288, -0.3180572,...
Pressure-adaptive differences in lactate dehydrogenases of congeneric fishes living at different depths.
The muscle-type (M4) lactate dehydrogenases of Sebastolobus altivelis, a deep-water scorpaenid, and S. alascanus, a shallower species, are electrophoretically indistinguishable, yet differ in pressure sensitivities. The lactate dehydrogenase of S. altivelis exhibits lower pressure sensitivities of substrate and coenzym...
208,149
[ 0.1172433, -0.2415528, -0.09050279, -0.02082389, -0.3529751, -0.148846, -0.2075213, 0.05403385, 0.1370974, 0.04842275, -0.03716818, -0.4173533, 0.05470584, 0.08158481, -0.2572105, -0.01729296, -0.5723536, 0.07632919, 0.1597366, 0.190167, 0.1375843, -0.09713265, -0.3344367...
Retrograde amnesia produced by several treatments: evidence for a common neurobiological mechanism.
This experiment examined the effects on memory of various amnestic treatments in animals earlier treated with the alpha-adrenergic antagonist phenoxybenzamine (PBZ). Thirty minutes before being trained in a one-trial inhibitory (passive) avoidance task, animals received an injection of PBZ or saline. Immediately after ...
208,153
[ -0.2373838, 0.05447015, -0.04507987, -0.2447658, 0.2989727, -0.4423749, -0.2537341, -0.3600976, 0.1022688, 0.07770116, 0.05685883, 0.3886314, 0.1477072, 0.06436738, -0.05698046, 0.03616239, -0.4417817, -0.02819705, -0.1689419, 0.09633175, 0.2758668, -0.2176739, 0.03873423...
[Inhibition of alkaline phosphatase I of Pichia guilliermondii yeast in vitro and in vivo].
The rate of p-nitrophenyl phosphate and flavin mononucleotide (FMN) hydrolysis by the partially purified preparation of alkaline phosphatase I of Pichia guilliermondii flavinogenic yeast was studied as affected by different substrates and inorganic ions. Their Km was established to be 2.0 X 10(-4) m and 2.5 X 10(-4) M,...
208,203
[ -0.168143, -0.4192323, -0.3660993, -0.00348699, 0.07528634, 0.1112511, 0.1708715, 0.3162317, -0.2912508, -0.1214223, 0.05721429, -0.08866626, 0.05785194, -0.1856783, -0.9436843, -0.02377763, -0.3538673, 0.07204534, -0.2804612, 0.5758863, 0.4065716, 0.0852166, -0.1602001, ...
[Effect of ions on determination of 3',5'-AMP by the method of saturation].
The effects of La2+, Pb2+, Ba2+, Zn2+, Ca2+, Mg2+, Mn2+, NH+4 in concentrations of 10(-7), 10(-5), 10(-3) M were studied as applied to the protein binding of cyclic 3' : 5' = AMP. It is shown that Ba2+, La2+, Pb2+ increase the binding, while Zn2+ has no effect, and Mn2+, NH+4 decrease the binding of 3' : 5' = AMP. The ...
208,205
[ 0.05904859, -0.2733079, -0.2687641, 0.03054577, -0.1286359, -0.1532876, -0.2159932, 0.2805793, -0.1448747, -0.05432045, -0.08092142, 0.1312522, 0.2082647, 0.0892667, -0.7549657, -0.2465648, -0.3023899, -0.01010583, -0.3058698, 0.4199049, 0.706255, 0.05076515, -0.1292479, ...
Fluorometric microassays of adenylate kinase, an enzyme important in energy metabolism.
The adenylate kinase system offers a mechanism for the rapid provision of energy by catalysing the production of ATP from ADP. Fluormetric micromethods were developed for determination of the activity of this enzyme using either formation of ADP or ATP, in each case measured by coupling to suitable dehydrogenase reacti...
208,211
[ 0.009034224, -0.08494791, -0.1192386, 0.02446834, 0.2002248, -0.2437343, -0.2422097, 0.5470443, 0.0874119, 0.1060249, 0.1888172, -0.3724431, 0.1904321, 0.007624333, -0.3779116, -0.2395803, -0.2482514, 0.1823722, -0.1896158, 0.1937513, 0.4291815, -0.07339875, -0.03139598, ...
[Effect of the prolonged administration of the atherogenic fractions of lipoproteins on the blood and myocardial lipid picture in rabbits].
Homologous total fraction of pre-beta and beta-lipoproteins, isolated from intact animal blood and administered intravenously into rabbits within 1.5-2 months, caused distinct alterations in lipid spectra of rabbit-recipient blood serum. The phenomenon was manifested as an increase in concentration of all the lipid com...
208,285
[ -0.07252482, -0.04945078, -0.4235979, -0.09927913, 0.4345237, -0.247861, -0.2321719, 0.1265494, 0.0350764, 0.001315323, -0.04264593, 0.06051762, 0.2349366, 0.02113354, -0.6043549, -0.1257877, -0.3825852, 0.01495217, 0.2727206, 0.4052154, 0.3779257, 0.3380192, -0.113526, ...
[Synthesis of RNA fractions in rat liver during single and multiple stimulation of the hypothalamus].
Specific radioactivity of RNA from rat liver tissue, labelled with 14C-orotic acid and fractionated using thermic phenol method, was altered dissimilarly. In single stimulation of hypothalamus the specific radioactivity of nuclear RNA was increased in RNA-40 degrees fraction than in RNA-55 degrees and RNA-63 degrees on...
208,294
[ 0.01883831, -0.05637348, 0.08489455, 0.1106516, 0.1143778, -0.2862563, -0.3558362, 0.01222973, -0.03102726, -0.01060662, 0.2467805, -0.02540357, 0.1495831, -0.1651957, -0.6463073, 0.2266474, 0.09379347, 0.2105964, -0.09352182, 0.3194449, 0.1704921, 0.05109447, -0.344691, ...
[Use of the monkey pox virus for evaluating the intensity of the immunity against smallpox in experiments on M. rhesus].
Monkeypox virus causing in M, rhesus upon aerogenic infection a disease similar to human varioloid was used to evaluate the intensity of immunity against smallpox in immunized M. rhesus monkeys. Postvaccination immunity was solid in all the animals vaccinated intradermally or orally. In 2 out of 14 monkeys immunized or...
208,308
[ -0.09292427, -0.4107849, 0.02522905, -0.2620348, 0.04839966, 0.0980718, -0.4492637, -0.03018178, -0.4241587, -0.1860544, 0.1703743, 0.05250447, 0.2448337, 0.08285582, -0.5134921, -0.2932259, -0.4483626, -0.03762976, 0.1489578, 0.209207, 0.3916141, 0.1320459, -0.0106762, ...
[Rational method of obtaining sera with a high titre of virus-neutralizing antibodies. Report 2].
In addition to report I (ZHMEI, 1977, No. 1) a study was made of 9 more schemes of rabbit immunization with the poliomyelitis virus, type I, for the purpose of obtaining the neutralizing sera of high titre. Vitamins A and C were used in the experiments in the capacity of the activators of the organism reaction; Freund'...
208,328
[ -0.05352812, -0.1125811, -0.1484194, 0.189105, 0.4042273, 0.0263816, -0.3709533, 0.3451322, -0.284963, -0.03133968, 0.1506344, 0.2298696, 0.5208492, 0.05484386, -0.1441035, -0.03003457, -0.2720754, -0.1679243, -0.1426162, 0.5579332, 0.3486866, 0.05217922, -0.0782352, 0....
Conversion of the electrophoretic pattern of type IV hyperlipidaemia to type III by intravenous heparin.
Heparin was given i.v. to subjects with type IV hyperlipoproteinaemia who had only ordinary pre-beta lipoproteins and no late pre-beta lipoproteins (LP-beta) in their very low density lipoproteins (VLDL, d less than 1.006) upon agarose gel lipoprotein electrophoresis. Within 15 min the electrophoretic pattern of VLDL h...
208,351
[ -0.06216595, 0.09630464, -0.370909, 0.05038336, 0.5309194, -0.2234686, -0.1827913, 0.1179113, -0.07016597, 0.1336516, 0.06575112, 0.2974567, -0.02506335, 0.1258098, -0.2765855, -0.171683, -0.3937697, -0.007284578, 0.1303251, -0.1578527, 0.09530035, 0.2788419, -0.1066253, ...
The effects of amphiphilic compounds on phosphatidate metabolism.
Amphiphilic cations interact with phosphatidate and thereby change its physical properties. This interaction can redirect phospholipid metabolism. In the presence of Mg2+ amphiphilic cations inhibit the activity of phosphatidate phosphohydrolase and stimulate that of phosphatidate cytidylyltransferase. Increasing the c...
208,356
[ -0.2526118, 0.04450445, -0.2841488, 0.03044858, 0.005021496, -0.003144149, -0.2589494, 0.1690289, 0.08467729, -0.005385192, -0.06907295, 0.1503571, 0.08332467, 0.3248266, -0.656549, 0.04381295, -0.541517, 0.05432909, -0.1774396, 0.3362031, 0.1709143, 0.1849547, -0.1492843...
Effect of zinc and other chemical agents on foot-and-mouth-disease virus replication.
Chemical agents reported to inhibit the growth of various ribonucleic acid and deoxyribonucleic acid viruses were tested against foot-and-mouth disease virus in cell culture. These included Zn(2+), aurintricarboxylic acid, polyribocytidylic acid, polyriboinosinic acid, phosphonoacetic acid, and the viral contact inacti...
208,461
[ -0.4421917, -0.0365698, -0.2904865, 0.1681047, 0.1929829, 0.1026574, -0.168924, 0.3245304, 0.1842288, 0.1182004, -0.1060106, 0.07630759, 0.1711668, 0.04029921, -0.1454867, 0.008162875, -0.08619581, -0.07591984, -0.3485175, 0.602302, 0.2174616, 0.2080513, -0.3348888, 0.0...
Treatment with levamisole of recurrent herpes genitalis.
A double-blind study was carried out to investigate the possibility of therapeutic effect of levamisole on recurrent progenital herpes. One hundred and nine patients, including 53 females, entered the study, but only 75 completed. Levamisole, 50 mg three times daily for 3 days, was started at the first sign of recurren...
208,462
[ 0.2881131, 0.124527, -0.1507807, -0.2276028, -0.0521839, -0.2191504, 0.01570201, -0.2235093, -0.03721842, -0.2417242, -0.07782903, -0.1704844, -0.0668553, 0.176314, -0.35757, 0.173559, 0.1290863, 0.3187023, -0.02109488, 0.3916996, 0.01851541, 0.2221339, -0.07444457, 0.1...
Male breast cancer: a clinicopathologic study of 97 cases.
From 1949 through 1976, 97 men have been treated at Memorial Hospital for primary operable breast cancer. Seven per cent had intraductal carcinoma. Of the patients with invasive carcinoma 30% were pathologic stage I, 54% stage II, and 16% stage III. Fourty-six per cent had pathologically negative axillary lymph nodes. ...
208,472
[ -0.08012722, -0.01022016, -0.230301, -0.4791086, -0.3592009, 0.03394721, 0.1355479, -0.187435, -0.02909615, 0.2238788, 0.02254136, 0.1754964, -0.007475012, -0.1771598, -0.1292281, -0.5465176, 0.08182748, 0.04342697, 0.297581, -0.2785248, 0.3862944, 0.3025543, 0.02398441, ...
Pathogenesis of Marek's disease in chickens with maternal antibody.
Histopathological lesions were studied in chickens with maternal antibody against MD virus at 14-day intervals after their exposure by contact to HPRS-16 of MD virus in the first-day of life. The first lesions occured 14 days after infection in the liver, kidney, heart, brain and the sciatic nerves. Relatively, the mos...
208,481
[ -0.4292173, 0.009660406, 0.1307606, -0.1368664, 0.07089169, -0.4038594, -0.3098087, 0.1408021, -0.1196963, 0.1761647, 0.06450956, -0.04437097, 0.371796, 0.08709534, -0.3143263, 0.3239664, -0.6064096, -0.3591976, -0.01146508, 0.1661689, 0.3127562, 0.120967, -0.2847918, -...
Detection of Mason-Pfizer monkey virus infection by syncytia formation of human cells doubly transformed by Rous sarcoma virus and simian virus 40.
Human cells doubly transformed by Rous sarcoma virus and SV40 (RSb cells) formed syncytia by cocultivation with Mason-Pfizer monkey virus (MPMV)-producing cells. This cell fusion was blocked by anti-MPMV serum indicating that the phenomenon is MPMV specific. The RSb cells were successfully used for MPMV infectivity ass...
208,492
[ 0.1740118, -0.08161991, -0.03400157, -0.2272563, 0.07728116, 0.1612665, -0.1882816, 0.1447967, 0.1621633, -0.1817056, 0.1470786, 0.225233, -0.05821857, 0.03027916, -0.591207, -0.2351423, -0.2473343, -0.02771885, 0.02733401, -0.03999749, 0.2501953, 0.05128, -0.09036587, ...
Partial purification and properties of branched-chain 2-oxo acid dehydrogenase of ox liver.
1. A branched-chain 2-oxo acid dehydrogenase was partially purified from ox liver mitochondria. 2. The preparation oxidized 4-methyl-2-oxopentanoate, 3-methyl-2-oxobutyrate and D- and L-3-methyl-2-oxopentanoate. The apparent Km values for the oxo acids and for thiamin pyrophosphate, CoA, NAD+ and Mg2+ were determined. ...
208,515
[ -0.3100623, 0.02751931, -0.1952737, 0.01780142, 0.1439998, -0.07312323, -0.01864357, 0.2183103, -0.1988993, -0.2359584, 0.05896835, 0.1182336, 0.1816406, 0.2564979, -0.9465563, 0.2380666, -0.7215223, 0.364848, 0.2220267, 0.6225975, 0.211491, 0.3249043, -0.05246061, 0.20...
Sterol balance in a patient with abetalipoproteinaemia.
Total-body cholesterol synthesis was measured in a woman with abetalipoproteinaemia and in a normal woman of similar age. The rate of synthesis of cholesterol was 15.4 +/- 4.1 mg/kg/day in the patient and 14.3 +/- 2.6 mg/kg/day in the control subject, indicating that cholesterol synthesis in the whole body is not incre...
208,591
[ -0.1468939, 0.107779, -0.1195544, -0.2865253, 0.09571347, -0.1843405, -0.2645292, -0.0543816, 0.01001066, -0.1364067, 0.1524087, 0.1759942, 0.1748522, 0.318597, -0.365845, -0.1094367, -0.5215055, 0.06935272, -0.2402854, 0.3421804, 0.1245573, 0.3289983, -0.0526612, -0.06...
Complex sporadic colobomata.
Sporadic colobomata may be associated with a variety of secondary changes, and these have been classified and discussed with special reference to unusual findings published during recent years. Clinically some cases may appear to be neoplastic, and pathological examination may be important in demonstrating their true n...
208,594
[ -0.1591547, -0.02198929, -0.1125112, -0.2081945, -0.1083493, -0.3215522, -0.2615143, -0.1596936, 0.1515661, 0.2394592, 0.2978503, 0.4143256, 0.06813016, -0.04550515, -0.3072474, -0.1477055, -0.4299914, -0.08758439, 0.1274562, -0.01214472, 0.2743645, 0.1577088, -0.109581, ...
Low-temperature studies of electron transfer between different cytochromes c and cytochrome c oxidase.
The ability of various native and modified cytochromes c to transfer electrons to cytochrome oxidase is compared in cytochrome c depleted beef heart mitochondrial particles. The kinetics are followed at -49 degrees C after the reaction is initiated by photolysis of the CO compound of cytochrome oxidase in the presence ...
208,599
[ -0.03654394, -0.1453754, -0.1841417, 0.2979563, -0.04062138, 0.03063856, -0.1014527, 0.05953831, 0.1804603, 0.1654751, -0.1955895, 0.1641285, 0.3410452, 0.01421908, -0.8583254, 0.2424828, -0.8377294, -0.2023675, 0.07858968, 0.119338, 0.4357194, 0.5897221, 0.00856423, 0....
Asymmetric distribution of phosphatidylethanolamine fatty acyl chains in the membrane of vesicular stomatitis virus.
The membrane of vesicular stomatitis virus (VSV) contains two distinct pools of phosphatidylethanolamine molecules which reside in the inner and outer phospholipid monolayers, respectively. 36% of the total membrane phosphatidylethanolamine is found in the outer monolayer while 64% is found in the inner. The two pools ...
208,607
[ -0.2085885, 0.02164802, -0.505271, -0.3079067, 0.3669143, -0.1769065, 0.08364204, 0.1205429, -0.1498618, 0.05884524, -0.1034322, 0.09196728, -0.03605543, 0.3813686, -0.1601178, -0.2957615, -0.554395, 0.182842, -0.4372877, 0.2665661, -0.005115434, 0.2442939, -0.3133734, ...
Characterization and comparison of poly(adenosine dephosphoribose) synthesis and DNA synthesis in nucleotide-permeable cells.
Using eukaryotic cells that have been rendered permeable to exogenously supplied nucleotides, we have characterized the activity of the poly(adenosine diphosphoribose) (poly(ADPR)) synthesis system and compared it to the DNA synthesis complex. The synthesis of poly(ADPR) is dependent on the presence of NAD and Mg2+. It...
208,614
[ -0.07233394, -0.1209043, -0.1775308, 0.0955097, 0.01624176, -0.2660569, -0.2329754, 0.1920713, -0.02280875, 0.3404951, -0.03606855, 0.1349318, 0.0126904, 0.3419509, -0.4608478, -0.0241871, 0.02894799, 0.3578859, -0.1755517, 0.3299476, 0.5716497, -0.08421841, -0.1519002, ...
Canine pulmonary angiotensin-converting enzyme. Physicochemical, catalytic and immunological properties.
Antiontensin-converting enzyme (peptidyldipeptide hydrolase, EC 3.4.15.1) has been solubilized from canine pulmonary particles and purified to apparent homogeneity. A value of approx. 140000 was estimated for the molecular weight of the native and the reduced, denatured forms of the enzyme. No free NH2-terminal residue...
208,622
[ -0.2626335, -0.02917569, -0.4653783, 0.09960384, -0.1495668, -0.3774933, -0.1584103, 0.1085797, -0.1790096, -0.01692003, 0.2272016, -0.08477067, 0.001531154, -0.5564104, -0.3454013, 0.3832999, -0.3305193, 0.3533632, 0.1600123, 0.3453656, 0.08198643, 0.2280188, -0.4891246,...
Cellular cyclic AMP in dispersed mucosal cells from guinea pig stomach.
In dispersed mucosal cells from guinea pig stomach cyclic AMP was increased 4-fold by theophylline, 5-fold by prostaglandin E2, and 10- to 15-fold by histamine. Theophylline augmented the increase in cellular cyclic AMP caused by histamine or prostaglandin E1 and the actions of histamine and prostaglandin E1 were addit...
208,634
[ -0.2557366, -0.3720261, -0.2478662, 0.003511232, 0.3136363, 0.0650247, -0.1349187, 0.04230438, 0.249349, 0.3040545, 0.2990133, -0.1455075, -0.2470301, 0.1723988, -0.5064876, 0.1339725, -0.7118992, -0.01802933, -0.07736441, 0.3727596, 0.363878, -0.03351922, -0.006364973, ...
Hormone-specific responses and biosynthesis of sulfolipids in cell lines derived from mammalian kidney.
The established cell lines isolated from mammalian kidney were characterized by its receptor activities against hormones and the ability to synthesize sulfolipids localized in the renal tubule. The level of 3':5'-cyclic AMP in JTC-12.P3 (monkey kidney) cells increased in 2 min as much as 2.5-5-fold on activation with 1...
208,643
[ -0.1715976, -0.2702706, -0.1416153, -0.2210766, 0.18279, -0.1414191, -0.1398189, 0.444746, -0.06081013, -0.04005009, 0.01120228, -0.2951356, -0.05605103, 0.1231945, -0.670772, -0.2224114, -0.08575817, 0.09032533, 0.09887201, 0.3206494, 0.2080994, 0.2561097, -0.2841521, ...