title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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In vivo antitumor activity of various forms of delayed-type hypersensitivity in mice. | Relationships among various forms of delayed-type hypersensitivity (DTH) and nonspecific resistance to Lewis lung tumor were studied in syngeneic and semisyngeneic mice. Only the tuberculin type of DTH obviated a virulent inoculum of 10(6) tumor cells. The Jones-Mote type of DTH, even modified by cyclophosphamide pretr... | 283,275 | [
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Antiviral effect of N-phenylacetoaminomethylene-DL-p-nitrophenylalanine (A-101) on murine leukemia viruses. | N-Phenylacetoaminomethylene-DL-p-nitrophenylalanine (A-101), when administered ip to male DDY mice infected with Friend leukemia virus, significantly inhibited virus-induced splenomegaly, reduced viable virus titers in spleen and plasma, and significantly prolonged survival time. A-101 also inhibited multiplication of ... | 283,285 | [
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Correlation between concanavalin A agglutinability and cytotoxic sensitivity to antiserum against tumor-associated antigen in rat fibrosarcoma cells. | An ip transplantation of 3-methylcholanthrene-induced, transplanted fibrosarcoma KMT-17 cells (1 X 10(8)) grew rapidly and killed syngeneic WKA rats in 3-4 days. Agglutinability induced by concanavalin A (Con A) and antigenic expression of KMT-17 cells were investigated in relation to days after ip transplantation. Agg... | 283,287 | [
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Abortion: some observations on the contraceptive practice of women referred for psychiatric assessment in Dunedin. | Factors associated with the contraceptive practice of 31 women referred for psychiatric assessment prior to therapeutic termination of pregnancy are analysed. Poor contraceptive practice is a significant contributing factor to the increasing rate of unwanted pregnancy and abortion. More research at a psychological leve... | 283,327 | [
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Pre-anaesthetic administration of dantrolene sodium to a patient at risk from malignant hyperthermia: case report. | The pre-anaesthetic administration of dantrolene sodium to individuals at risk from malignant hyperthermia has not yet found an accepted place in human anaesthetic practice, although the effectiveness of dantrolene sodium as a prophylactic drug has been clearly shown in animal studies. In the patient described in this ... | 283,330 | [
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Delayed healing of mandibular fracture in idiopathic myxedema. | Lack of adequate amount of thyroid hormone may interfere with healing. A patient in whom a fracture of the mandible failed to heal in the 2 years following surgical treatment is presented. When thyroid hormone supplementation was introduced, the fracture progressed to union. The physical findings of hypothyroidism and ... | 283,355 | [
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Microscopic study of standardized gutta-percha points. | Eleven brands of gutta-percha cones were analyzed with the optical microsocpy, showing deformations in the apical thirds which would not allow the correct adaptation of them in the apical section of the root canal. | 283,357 | [
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The free focus concept in dental and maxillofacial radiography. The present status of the miniaturized dental x-ray machines. | "Free focus" radiography has shown promise in the examination of complex anatomy in many parts of the body, where conventional and tomographic exposures provide limited information. The approach was introduced in dentistry three decades ago and applied clinically from the time the miniaturized x-ray machines with rod a... | 283,359 | [
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Effect of anesthetics and pressure on the thermotropic behavior of multilamellar dipalmitoylphosphatidylcholine liposomes. | The effects of gaseous anesthetics and pressure on the thermotropic behavior of multilamellar dipalmitoyl-phosphatidylcholine liposomes were studied by using a high-sensitivity differential scanning calorimeter. It was found that halothane and enflurane decreased the transition temperature and increased the width of th... | 283,401 | [
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Mid-G1 marker protein(s) in 3T3 mouse fibroblast cells. | Quiescent 3T3 mouse fibroblast cells in a state of growth arrest due to serum deprivation were exposed to [14C]isoleucine. The cell cultures were then stimulated by the addition of 10% fetal calf serum. At various times after stimulation, the 14C-labeled cells were exposed to [3H]isoleucine. Cytoplasmic extracts from t... | 283,406 | [
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Induction of ornithine decarboxylase activity in a temperature-sensitive cell cycle mutant of Chinese hamster cells. | We have investigated the induction of ornithine decarboxylase (L-ornithine carboxy-lyase, EC 4.1.1.17) activity in a temperature-sensitive cell cycle mutant of Chinese hamster fibroblasts. This activity is not induced at the nonpermissive temperature, although the synthesis of the majority of proteins is normal. From a... | 283,409 | [
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Primary treatment of craniofacial injuries. | This presentation offers analysis of findings and treatment of 15 patients who suffered cranio-facial injury. 4 of them sustained isolated fractures of the glabella and supra-orbital margin; the remainder suffered disruption of the facial and cranial skeleton. In all cases, the possibility of dural tear with C. S. F. l... | 283,524 | [
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[Study of the variability of pre-maxillary angulation in relation to maxillo-mandibular basal separation in an antero-posterior direction. 109 orthodontic cases (author's transl)]. | On the basis of a routine study in 109 children of variations in pre-maxillary angulation, the authors feel that the pre-maxilla is a typical example of a basic osseous structure whose direction of growth is adapted to the muscular conditions which surround it. | 283,525 | [
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[A new case of basal cell naevomatosis (author's transl)]. | The authors, in the light of a new case of naevomatosis, review the description of the disease, emphasising its symptoms and signs, and inheritance, drawing attention to the need for surveillance of such patients in view of the risk of malignant change in the naevi. The other signs of the disease must be sought followi... | 283,529 | [
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[Use of a semi-rigid plastic material: value and possibilities]. | The use of semirigid plastic material is shown in its use in orthodontia, in the chair and in the laboratory. The products: vestibular screen, shaped in the mouth, the "bumper" for the correction of fan shaped lower anteriors, tooth positioners which serve to correct slight positional occlusal dysharmonies. The use of ... | 283,554 | [
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Gilles de la Tourette syndrome. Interactions with other neuropsychiatric disorders. | Gilles de la Tourette syndrome is a neuropsychiatric disease with a childhood onset below age 16, characterized by chronic involuntary movements, obsessions, compulsions, utterances, echolalia, coprolalia and aggressive behavior symptoms. Two unique case histories are described in this report, one with an intercurrent ... | 283,685 | [
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A family with acute leukemia, hypoplastic anemia and cerebellar ataxia: association with bone marrow C-monosomy. | The eldest brother in a sibship of five children died of acute myelogenous leukemia at 10 years of age. The second and third eldest brothers died of hypoplastic anemia at ages five and nine years, respectively. A surviving 6 year old brother, the proband of the study, has abnormalities that suggest a preleukemic state:... | 283,689 | [
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Effects of orthodontic intermaxillary class III mechanics on craniofacial structures. Part II - computerized cephalometrics. | The relation between active growth and induced anatomic changes was examined using a computerized cephalometric analysis of ten Class III cases treated with intermaxillary traction. The following can be concluded from this investigation: 1. Mandibular growth was redirected and mandibular opening was observed due to max... | 283,707 | [
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Facial growth associated with a cranial base defect - a case report. | A skull was described possessing posterior cranial base defect and resultant asymmetric growth of this structure. It was hypothesized that compensatory restraining influences of surrounding soft tissues prevented a more severe facial malformation from occurring. | 283,709 | [
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Clinical features and plasma hormone levels after surgical menopause. | This study reports the plasma levels of follicle stimulating hormone, luteinising hormone, oestradiol and testosterone in 43 women who had undergone bilateral oöphorectomy. Age was the only variable of those investigated which appeared to influence a hormone level; testosterone levels were found to decrease with increa... | 283,784 | [
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Perceptions of dentofacial morphology by laypersons, general dentists, and orthodontists. | Line drawings of facial profiles and color photographs of dentitions were evaluated subjectively by 1,150 parents, 72 general practictioners of dentistry, and 54 orthodontists with regard to the normality and abnormality in dentofacial morphology and the need for orthodontic treatment. A significant difference was foun... | 284,066 | [
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Human serum hexosaminidase: elevated B form isozyme in cancer patients. | The activity of N-acetyl hexosaminidase (beta-2-acetamido-2-deoxy-D-glucoside:N-acetamido-deoxyglucohydrolase, E.C. 3.2.1.30) was significantly greater in sera of patients with solid malignant tumors than in sera of healthy volunteers or of patients with nonmalignant ailments. The increased activity was found in the tw... | 284,076 | [
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Dupuytren's disease presenting as palmar pits. | A 37 year old man with a non-Hodgkin's lymphoma and a history of heavy alcohol use presented with bilateral palmar pits. Similar lesions were noted in several family members, some of whom had limited use of the hands. Although the patient was referred for evaluation of the palmar pits of the basal cell nevus syndrome, ... | 284,078 | [
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[Free gingival graft in mucogingival surgery]. | Palatine grafts, which today represent the simplest and most reliable technique for enhancing the adherent gum--a problem of great importance in periodontal treatment--are discussed together with other techniques designed for the same purpose. Bone site palatine grafts which restore adherent gum on the alveolar bone, a... | 284,174 | [
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[Lateral sliding flaps in mucogingival surgery]. | Reference is made to parodontal surgery techniques employing lateral sliding flaps mucogingival for the treatment of gingival schisis. Grupe & Warren (1965) proposed the use of a flap from the parts contiguous to that affected by the schisis. The technique was then developed by the introduction of bipapillar flaps ... | 284,173 | [
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Gilles de la Tourette syndrome after long-term chlorpromazine therapy. | Following 6 years of continuous chlorpromazine therapy for schizophrenia, a young woman developed multifocal tics and vocalizations characteristic of Tourette syndrome. The symptoms first appeared when chlorpromazine was withdrawn. They were permanent, although partially ameliorated by chronic haloperidol therapy. Beca... | 284,201 | [
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Cryosurgical and thermal monitoring system for management of malignancy. | A comprehensive evaluation of the major aspects of cryosurgery has been explored in this preliminary study. A thermal monitoring system has been used concomitantly with cryosurgery, and characteristic freezing pattern differences between normal and malignant tissue have been demonstrated. Morphologic examination of the... | 284,272 | [
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Fibrosarcoma of maxilla. Report of a case with histochemical studies. | A case of fibrosarcoma of the maxilla with strong alkaline phosphatase activity in the tumor cells is described, and the significance of this enzyme is discussed. | 284,280 | [
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0.09019709,
0.3000673,
0.3612414,
-0.07500026,
-0.0217289... |
DNA sequencing and melting curve. | The dependence of DNA absorbance (for light at about 260 nm) on temperature is related to a specific DNA sequence structure in the vicinity of DNA thermal denaturation (the so-called DNA melting or coiling). A straightforward analysis of the experimental DNA melting curve allows us to determine the lengths, the A+T con... | 284,324 | [
-0.2851529,
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0.09820929,
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0.2846088,
0.5912133,
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-0.27542... |
Location of the regulatory site for establishment of repression by bacteriophage lambda. | During the lysogenic response to infection by bacteriophage lambda, the phage-specified cII and cIII proteins provide for the coordinate establishment of repression and integration of the viral DNA. One critical regulatory function of cII/cIII is an activation of synthesis of the cI protein, the repressor that maintain... | 284,327 | [
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0.08819208,
0.2024468,
-0.2376061,
... |
Caulobacter crescentus nucleoid: analysis of sedimentation behavior and protein composition during the cell cycle. | The envelope-associated nucleoid (EAN) of Caulobacter crescentus has been isolated during major developmental stages in the cell cycle. The sedimentation coefficient of the Caulobacter EAN changes as a function of development and is closely correlated with the periodicity of DNA synthesis in this bacterium. The contrib... | 284,329 | [
-0.06729464,
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0.36615,
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... |
Helical repeat of DNA in solution. | The helical repeat of DNA in solution has been measured directly by analyzing the gel electrophoretic patterns of pairs of covalently closed DNAs with length differences between 1 and 58 base pairs, out of a total length of about 4350 base pairs per DNA molecule. The method is based on the observation that for a covale... | 284,332 | [
-0.08026114,
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0.1899241,
0.389773,
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-0.... |
Procollagen segment-long-spacing crystallites: their role in collagen fibrillogenesis. | Naturally occurring segment-long-spacing crystallites of procollagen collagen have been found in the culture medium of fibroblasts from chick embryo tendon, human skin, and dermatosparaxic calf skin; in whole-mount preparations of cultured human skin fibroblasts; in homogenates of lathyritic chick embryo tendon, cartil... | 284,347 | [
-0.2004091,
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0.4733979,
0.1734368,
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Conservative segregation of parental histones during replication in the presence of cycloheximide. | Long stretches of protein-free, nonbeaded DNA were observed electron microscopically in nuclear spreads prepared from cells that had replicated their DNA in the absence of protein synthesis. The amount of this DNA increased with increasing time of replication in the presence of cycloheximide and was greatly decreased w... | 284,348 | [
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0.401031,
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-0... |
Evolutionary change in 5S RNA secondary structure and a phylogenic tree of 54 5S RNA species. | Secondary structure models of 54 5S RNA species are constructed based on the comparative analyses of their primary structure. All 5S RNAs examined have essentially the same secondary structure. However, there are revealing characteristic differences between eukaryotic and prokaryotic types. The prokaryotic 5S RNAs may ... | 284,354 | [
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0.06527761,
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0.2030252,
-0.0916... |
Identification of a non-H-2 gene (Rfv-3) influencing recovery from viremia and leukemia induced by Friend virus complex. | The dominant C57BL/10 allele of a single autosomal, non-H-2 gene (Rfv-3) was found to be required for recovery from viremia and leukemia induced by Friend virus complex in H-2b/b mice. In H-2a/a mice, the Rfv-3 gene apparently influenced recovery from viremia in the presence of persistent leukemia because these mice la... | 284,359 | [
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0.04726784,
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... |
Distribution of binding sites for 125I-labeled alpha-bungarotoxin in normal and deafferented antennal lobes of Manduca sexta. | 125I-Labeled alpha-bungarotoxin has been used to determine the distribution of putative acetylcholine receptors in normal and chronically deafferented antennal lobes in the brain of the moth Manduca sexta. Toxin-binding sites are confined to synaptic regions in deafferented lobes. These findings suggest that receptors ... | 284,367 | [
0.137031,
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0.1641717,
0.1642001,
0.07985874,
-0... |
Prolyl-leucyl-glycinamide, cyclo(leucylglycine), and derivatives block development of physical dependence on morphine in mice. | Pro-Leu-Gly-NH2 (MIF) and several structural analogues, all injected in 50-microgram doses daily in mice receiving morphine chronically, were found to prevent development of physical dependence as measured by changes in body temperature associated with naloxone-induced withdrawal. Dose-response studies, using again a p... | 284,370 | [
-0.09191458,
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0.479917,
0.2435016,
0.8938132,
-0.007360796,
0.07681888,
0.0351059... |
Amino-acid sequence of Tetrahymena histone H4 differs from that of higher eukaryotes. | A partial amino-acid sequence of Tetrahymena histone H4 has been determined and differs significantly from the sequence of calf or pea H4. The amino terminus of Tetrahymena H4, unlike that of other H4s so far examined, is not acetylated. Of 66 residues determined, one is a single-residue insertion, one a single-residue... | 284,382 | [
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0.1351996,
0.4431566,
0.05294027,
-0.1... |
Preparative and analytical purification of DNA from agarose. | Two procedures were developed for removing DNA from agarose after electrophoretic separation of DNA fragments according to size. Both involve dissolving the DNA-containing agarose in NaI. The preparative technique uses binding of DNA to glass in the presence of NaI. The method is rapid and convenient, and DNA of all mo... | 284,385 | [
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0.262853,
0.458027,
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Human leukocyte interferon: production, purification to homogeneity, and initial characterization. | A method of fractionating proteins by high-performance liquid partition chromatography has been developed and used for isolation and purification to homogeneity of one of the species of human leukocyte interferon. The homogeneous interferon exhibited a sharp peak on high-performance liquid chromatography and a single n... | 284,389 | [
-0.08348662,
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0.02080755,
0.1553583,
0.4353371,
0.02591065,
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Adenovirus DNA replication in vitro. | A soluble extract from the nuclei of HeLa cells infected with adenovirus 5 (Ad5) carries out the semiconservative replication of exogenously added Ad5 DNA in vitro. Maximal DNA synthesis is observed when DNA-protein complex, isolated from Ad5 virions, is added as template. DNA-protein complex from virions of the closel... | 284,391 | [
-0.3266918,
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0.2047331,
-0.05625905,
0.08012015,
0.3397732,
-0.01597291,
-0.253733... |
Electrical currents through full-grown and maturing Xenopus oocytes. | An extracellular vibrating electrode was used to map the current pattern around Xenopus laevis oocytes. Current was found to enter the animal hemisphere and leave the vegetal hemisphere; in fully grown oocytes from which the follicle cells had been removed, the maximal current density was about 1 microamperemeter/cm2. ... | 284,407 | [
-0.01728246,
0.02088091,
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0.09640052,
0.3027876,
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0.4553001,
-0.008334775,
-0.03487788,
0.2903739,
0.19839,
0.007466... |
Genetic heterogeneity of "normal" human erythrocyte glucose-6-phosphate dehydrogenase: an isoelectrophoretic polymorphism. | Quantitative determination of glucose-6-phosphate dehydrogenase (G6PD; D-glucose-6-phosphate: NADP+ 1-oxidoreductase, EC 1.1.1.49) activity was carried out in 214 male Nigerian children of 84 mothers with known Gd genotype. The relative intrasibship difference in G6PD activity (normalized to the lowest value within the... | 284,409 | [
0.02063849,
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0.0790125,
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0.08527806,
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0.308906,
0.0677825,
0.... |
IgM receptors on human lymphocytes: detection by direct binding. | Radioiodinated IgM isolated from a patient with Waldenström macroglobulinemia binds with high avidity (apparent Ka = 2.5 x 10(9) M-1) to freshly isolated human peripheral blood lymphocytes. Binding occurred through the Fc region of the molecule and involved a receptor specific for immunoglobulins of the IgM class. The ... | 284,416 | [
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0.2181906,
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0.02505573,
-0.02897466,... |
Saliva secretion following long-term antidepressant treatment with nortriptyline controlled by plasma levels. | Eight patients undergoing antidepressant therapy with nortriptyline for 1--4 years were investigated. The period of the investigation was 7 weeks and included a 2-week placebo period, blind for the patients. Total saliva secretion measurement, the nortriptyline plasma level, and signs and symptoms of depression and sid... | 284,578 | [
-0.03730255,
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0.1209075,
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0.01617592,
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0.2745315,
0.0514... |
Morphologic studies of the erythropoietic part of bone marrow in myeloid leukaemias. | The erythropoietic part of the bone marrow has been morphologically analyzed in 147 patients with various forms of myeloid leukaemias and in 20 healthy controls. In all the patients the percentage of basophilic erythroblasts was abnormally high and correlated to elevated mitotic indices. Megaloblastic changes were foun... | 284,582 | [
0.02275955,
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0.3253735,
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0.1894837,
0.15973,
... |
Skeletal maturation of the hand in Iceland. | The mean time at onset of the stages of skeletal maturation of the hand, PP2=, MP3=, S, MP3cap, DP3u, PP3u, and MP3u, in a cross-sectional sample of Icelandic school chidren in Reykjavík, a total of 1426 (690 boys and 736 girls), was assessed on radiographs of the hand and compared with results published from Denmark a... | 284,704 | [
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0.2143434,
0.3287016,
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-0.3370803,
... |
Impairment of vitamin D and bone metabolism in patients with bypass operation for obesity. | Thirty-four patients were studied 2--6 years after jejunoileal bypass for morbid obesity. The serum concentration of 25-hydroxyvitamin D (25-OHD) were reduced and related to the frequency fo stools and to the weight reduction. Fifteen patients were not able to normalize serum 25-OHD following a long-term regular vitami... | 284,717 | [
-0.1851408,
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0.1744006,
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0.5624645,
0.134531,
0.4618513,
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0.... |
Clinical evaluation of hepatic scintigraphy. | The diagnostic accuracy of liver scintigraphy concerning focal liver diseases was evaluated. Two groups of patients were examined. The first group was examined with a rectilinear scanner and a definite diagnosis was obtained in 176 cases. The predictive diagnostic values of the scintigraphic diagnosis: focal liver lesi... | 284,718 | [
-0.1574854,
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0.4207358,
0.3376241,
-0.03786973,
0.1663941,
-0.006316646,
-0.1490266... |
Serum ferritin in pregnancy. | Serum ferritin levels were measured in 200 consecutive pregnant women at their first antenatal visit; 64 (32%) were found to have levels below the normal range. The results were correlated with haemoglobin concentration, serum iron levels, gestation, parity, and social class. The results indicate that low iron stores o... | 284,762 | [
-0.2557757,
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0.04523979,
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0.2158119,
-0.2518405,
0.3139504,
-0.2424295,... |
Prognostic aspects of endometrial carcinoma. | A retrospective analysis of 91 patients with endometrial carcinoma is presented with emphasis on important factors in relation to survival. Patients with Stage 1 carcinoma were treated with a standardized mode of preoperative radiation and extended abdominal hysterectomy. An 87.1% 5-year survival rate was obtained for ... | 284,770 | [
-0.1517397,
-0.1747032,
-0.5392062,
-0.5354528,
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0.1497921,
0.3306154,
0.390424,
-0.05348435,... |
Quantitative assay of the N-methylated metabolites of tryptamine and serotonin by gas chromatography mass spectrometry as applied to the determination of lung indoleethylamine N-methyltransferase activity. | A specific and sensitive method is described for the identifcation and quantification of the N-mono- and dimethylated derivatives of tryptamine and serotonin by gas chromatography mass spectrometry. Deuterated analogues of the amines have been prepared for use as internal standards. The technique has been applied to th... | 284,808 | [
-0.4420716,
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0.3635312,
-0.07442184,
0.2196912,
0.1720874,
0.2544259,
-0.069396... |
Analysis of 5-methoxytryptamine in brain by gas chromatography mass spectrometry. | A quantitative gas chromatographic mass spectrometric method using a deuterated analogue as internal standard were developed for the analysis of 5-methoxytryptamine in brain. The internal standard was synthesized in two steps and possessed high isotopic purity. The analytical procedure involves the addition of the inte... | 284,809 | [
-0.5831128,
0.1919302,
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0.1172399,
0.03990681,
0.1812506,
-0.2335654,
-0.1... |
Internal hemipelvectomy--excision of the hemipelvis with limb preservation. An alternative to hemipelvectomy. | Our results indicate that it is technically possible to resect the hemipelvis and maintain a viable extremity. Functional results are remarkably good and tumor control has been equivalent to standard hemipelvectomy. Excision of the ilium with preservation of the extremity in selected cases would appear to be a reasonab... | 284,841 | [
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0.07477276,
0.01569545,
0.03802558,
0.1473127... |
Information and experience with cleft palate: students, parents, professionals. | More than 1,200 students, parents, and professionals completed a questionnaire designed to assess knowledge and experience with cleft palate. Professionals knew more about cleft palate and had had more experience with it than either parents or students. Parents, however, knew more about cleft palate and had had more ex... | 284,871 | [
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-0.3461824,
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-0.2985859,
0.08464328,
-0.266475,
0.1554302,
-0.2075857,
0.002658315,
0.1651281,
-0.06742671,
0.0488... |
Attitudes concerning water fluoridation among graduating Swedish dentists. | The purpose of the investigation was to assess the attitudes concerning water fluoridation among Swedish dentists just having completed their dental education. All senior dental students (168) at the four Swedish dental schools were handed a questionnaire during the last week of November 1974. By the end of February 19... | 284,881 | [
-0.472838,
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0.3442... |
[Dental caries and the necessity of treatment in pre-school children]. | A study concerning the intensity of caries, the oral hygiene, and the necessity for treatment was carried out with 816 children between the ages of three and five. The findings indicated age-related relationships, which are independent of sex and kindergarten enrollment. On the basis of the results, the conclusion was ... | 284,897 | [
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0.04935371,
0.5514286,
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0.0251... |
Distribution patterns of DNA template activity in the embryonic tooth organ: an acridine orange ultracytochemical study. | The ultracytochemical acridine orange (AO) method has been employed to demonstrate DNA template activity within embryonic incisor tooth organs excised from New Zealand White rabbits during the 25th day of gestation. Survey ultrastructural examination revealed characteristic distribution patterns of AO positive cell pop... | 285,073 | [
-0.03537257,
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0.5450708,
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Tooth morphogenesis: the role of the innervation during induction and pattern formation. | The hypothesis is discussed that the innervation of the early mandibular and maxillary processes influences the initiation and patterning of tooth germs. Silver staining of embryonic mouse tissue supports the notion that the innervation is present before tooth buds appear. Data from other experimental studies is discus... | 285,074 | [
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0.3654174,
0.3225523,
-0.04346444... |
Cariostatic activity of (1,6-bis-[2-ethylhexylbiguanido]-hexane) in conventional rats. | The antimicrobial and cariostatic activities of the dihydrochloride and dihydrofluoride salts of alexidine (1,6-bis-[2-ethylhexylbiguanido]hexane) were compared to those of chlorhexidine acetate and sodium fluoride in rats implanted orally with Streptococcus mutans 6715 and fed a cariogenic diet. Experimental caries wa... | 285,110 | [
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0.2090072,
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0.3093742,
0.09... |
Effect of acrylonitrile on primary Syrian golden hamster embryo cells in culture: transformation and DNA fragmentation. | Application of acrylonitrile to primary Syrian golden hamster embryo cells (HEC) in culture produced foci of morphologically transformed cells. When similar cells were pretreated with simian adenovirus (SA7) and subsequently treated with acrylonitrile, up to an 8.9-fold increase in frequency of virus-transformed foci w... | 285,274 | [
-0.1730978,
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Neoplasms and pigmentation of thyroid glands in F344 rats exposed to 2,4-diaminoanisole sulfate, a hair dye component. | 2,4-Diaminoanisole sulfate was fed at dietary levels of 0.12% (low dose) or 0.5% (high dose) to groups of 50 male and 50 female inbred F344 rats for 78 weeks. By 107 weeks after the initial exposure, 58% of the male rats and 42% of the female rats administered the high dose had thyroid neoplasms, whereas only 7--8% of ... | 285,280 | [
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Effect of dietary fiber on azoxymethane-induced intestinal carcinogenesis in rats. | The effect of alfalfa, bran, and cellulose on intestinal tumor formation and fecal billary steroid levels was studied in male Sprague-Dawley rats given injections of azoxymethane (AOM). Animals received weekly injections of 8 mg AOM/kg and were fed diets containing 10% fiber (wt/wt) and 35% beef fat or 20 or 30% fiber ... | 285,283 | [
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0.03510388,
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Statistical issues in interpretation of chronic bioassay tests for carcinogenicity. | The interpretation of chronic bioassay tests for carcinogenicity requires that the data be appropriately recorded. A "case history" for each animal links the pathology data for each organ of each animal to the length of its life. This information can be used in interpretation of the tumor incidences in light of the sur... | 285,297 | [
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[Inherited hemolytic anemia due to pyruvate kinase deficiency: II. Density-layer centrifugation of erythrocytes (author's transl)]. | Heterogeneous clinical features of inherited hemolytic anemia due to pyruvate kinase (PK) deficiency were observed in three related homozygous patients. Erythrocytes were separated into old and young cells by means of density-layer centrifugation using a new supporting medium: Stractan-Urografin gradients. Those fracti... | 285,328 | [
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0... |
Nonmetastatic superior sagittal sinus thrombosis complicating systemic cancer. | Seven patients with cancer complicated by nonmetastatic sagittal sinus thrombosis were encountered in a 7-year period. Five had hematologic malignancies and two had solid tumors. There were two different presentations. In the first, neurologic signs and symptoms (e.g., headaches, seizures, hemiparesis, lethargy) occurr... | 285,338 | [
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0.2748954,
0.1190951,
0.42... |
Prospective study of convulsions in childhood. | One hundred and five children admitted to hospital with convulsions were studied prospectively. A convulsion was designated febrile if an axillary temperature of 38 degrees C or more occurred after the fit. Twenty-two children had an initial non-febrile convulsion and five of them (22.7 percent) have developed recurren... | 285,362 | [
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... |
Study of some erythrocytic enzymes in extracorpuscular hemolytic anemias. | Investigations on the activity of three erythrocytic enzymes i.e., glucose-6-phosphate dehydrogenase (G-6-PDH), catalase and lactate dehydrogenase (LDH), in 20 patients with extracorpuscular hemolytic anemias of various origins showed a general tendency to decrease of G-6-PDH and catalase, with a concomitant increase i... | 285,454 | [
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0.1593419,
0.1312985,
0.1531632,
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... |
[Viral hepatitis and dental practice]. | A description of the clinical features and epidemiology of viral hepatitis is followed by a literature survey of the problems concerning the relevance of viral hepatitis to dental practice. Most investigators have found, that in comparison to the general population dentists do have an increased risk of viral hepatitis.... | 285,471 | [
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0.02936082,
... |
Long-term follow-up of patients after retinal detachment surgery. | The value of long-term follow-up of patients after retinal detachment surgery depends on the number of further detachments prevented. This in turn depends on the frequency with which predisposing lesions are found and treated and also the risk of leaving them untreated. In a retrospective study of 128 patients who had ... | 285,501 | [
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0.241533,
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0... |
Intrascleral thermocautery. | Because of failure of trabeculectomy to normalize intraocular pressure in a significant number of patients, intrascleral thermocautery has been preferred since 1972. Over 200 eyes have been operated on and the results so far are satisfactory regarding the control of intraocular pressure and the absence of complications... | 285,504 | [
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0.001859829,
0.2458209,
0.1664715,... |
Congenital anophthalmos. Problems in management. | The management of congenital anophthalmos is difficult under the best of circumstances. Therapy is directed towards enlargement of the sorbet by expansion and/or surgical techniques. Early expansion therapy within the first year of life appears to be warranted in view of the differential orbital growth rates. | 285,505 | [
-0.09865852,
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Variable focus spectacles. | The history of prostheses for presbyopia is reviewed with an account of the development of variable focus spectacles. They have fluid-filled cells, with one flexible wall on the back of the base lens. The curvature of the flexible wall can be varied by operating a bellows in one side-arm. Their use for presbyopia, apha... | 285,517 | [
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0... |
A key to the understanding of extraoral forces. | By following certain basic principles, the effects, advantages, and disadvantages of the wide assortment of extraoral assemblies marketed are easily understood. The key to this understanding is the appreciation of the relationship of the line of action of the force application to the center of resistance of the tooth. ... | 285,613 | [
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0.1215... |
Surgical access: the access-line concept. | Adequacy of surgical access is determined by the position of the access line and not by the size of the flap as commonly believed. The case for small flaps in surgery is strongly argued for. | 285,666 | [
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Hypnotherapy in the treatment of oro-facial pain. | A continuing study at the Oro-Facial Pain Clinic. The Royal Dental Hospital of Melbourne has demonstrated that hypnotherapy is a useful tool in the management of previously resistant, chronic facial pain disorders, discomfort conditions and dental phobic illness. | 285,672 | [
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Intermittent atrioventricular block: procainamide administration as a provocative test. | Twelve patients with clinical features suggesting possible intermittent high degree atrioventricular block were studied. All 12 patients had basic 1:1 atrioventricular conduction but nine had an electrocardiographic pattern of bifascicular distal conduction disease (right bundle branch block with left anterior or poste... | 285,680 | [
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0.2... |
Surgical division of an accessory atrioventricular connection in the posterior septal region following ventricular fibrillation in the Wolff-Parkinson-White syndrome. | A young man presented with atrial fibrillation and a rapid ventricular response which degenerated into ventricular fibrillation. Electrophysiological study demonstrated an accessory atrioventricular connection in the posterior septal region. This was sectioned to prevent recurrence of his arrhythmia. Post-operative ele... | 285,687 | [
-0.1047946,
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... |
Spontaneous perforation of the common bile duct: report of a case. | A case is reported of spontaneous perforation of the common bile duct in a 59-year-old woman. Recurrent episodes of epigastric and right hypochondriac pain over one year culminated in the onset of obstructive jaundice. There were not signs of peritonitis, and laparotomy revealed an abscess surrounding a perforation in ... | 285,702 | [
-0.07114767,
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0.1625286,
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-0.07823834,
-0.0777... |
Aneurysmal bone cysts of the jaws: a case report and review of the literature. | A case of aneurysmal bone cyst of the mandible in a 21-year-old female has been presented, and the pertinent literature reviewed. Conservative surgery in the treatment of this type of jaw lesion is recommended. | 285,727 | [
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[Ectodermal dysplasia and exocrine pancreatic insufficiency--a familial syndrome]. | A syndrome was observed in two sisters which was characterized by a median defect of the hair of the head, hypoplasia of the ala nasi, absence of the permanent teeth, microdontia of the deciduous teeth, and exocrine insufficiency of the pancreas. This syndrome is probably autosomal regressive; the symptoms are similar ... | 285,801 | [
0.1385322,
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0.1737884,
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0.2637505,
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0.1550771,
0... |
Recent advances in EEG data processing. | It is argued that the most interesting advances in EEG signal processing are with methods based on descriptive mathematical models of the process. Formulation of auto-regressive (AR) and mixed autoregressive and moving average (ARMA) models is reviewed for the scalar and the multidimensional cases and extensions to all... | 285,831 | [
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Diagnostic value of quantitative electromyography. Its scope and limitations. | On the evidence of 951 cases of the 10,500 investigated with the aid of quantitative electromyography the author shows the value of the method for diagnosing muscle activity. Statistical analysis was applied to check the diagnostic value of EMG parameters separately and jointly in the identification of the pathology an... | 285,850 | [
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-0.3332536,
0.01845839... |
Periodic acid-Schiff reaction and prognosis in lymphoblastic leukaemia. | Diagnostic bone marrow smears from 132 patients with acute lymphoblastic leukaemia, (ALL) were stained simultaneously by the periodic acid-Schiff (PAS) reaction, and the blast cell positivity was assessed quantitatively. The patients fell naturally into two unequal groups: those with more than 20% PAS-positive blast ce... | 285,941 | [
0.3196529,
-0.2715332,
-0.3914134,
0.1142021,
0.05521719,
-0.1318987,
-0.007170263,
0.06049339,
-0.0066468,
-0.1162017,
-0.03119929,
0.560276,
-0.05187568,
0.3746904,
0.2092575,
-0.3257687,
-0.01440039,
0.007879318,
-0.2553973,
0.247161,
0.6413677,
0.07113607,
-0.2298682,... |
The alveolar flap for the repair of the cleft alveolus -- related to the development of the upper jaw. | A new method for the repair of the cleft alveolus employing the alvolar flap, was carried out in 33 patients with a unilateral total cleft. Alternating primary osteoplastic repairs were performed in in aqual number of patients. The postoperative interval varies between 8 and 9 years. The patients were followed up with ... | 286,004 | [
-0.3437154,
-0.1670817,
0.03695915,
-0.2366311,
0.08805147,
-0.3260366,
-0.2806652,
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0.2114269,
0.1895999,
0.0339962,
0.3048199,
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0.2555812,
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-0.05177352,
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-0.03604472,
-0.3167355,
-0.3183529,
0.2424338,
0.1354218,
-0.0692864,
... |
Some subjective-experiential parameters in experimental tooth clenching in man. | Experimental tooth clenching was performed by fourteen human subjects in order to determine the onset of the subjective sensations of jaw muscle fatigue and jaw muscle pains, the ability to endure jaw muscle pains, and other discomforts. During production of maximal voluntary isometric tension by the elevator jaw muscl... | 286,020 | [
-0.01777139,
0.06975733,
-0.2202058,
0.05109549,
-0.06966233,
-0.1995563,
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0.04096918,
0.01288532,
-0.4411839,
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-0.2708763,
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-0.7168525,
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-0.1816121,
0.2877373,
0.01859939,
0.2426211,
-0.1459... |
Physiologic dimensions of the periodontium significant to the restorative dentist. | When treating patients, the objectives of restorative therapy must be clear. The first and most basic objective is preservation of the teeth. The attainment of this objective would be far less complex if it could be considered independent of restoration of function, comfort and esthetics, but such is not the case. The ... | 286,038 | [
-0.2567903,
0.1242001,
-0.2081906,
0.01734436,
-0.01524337,
-0.3290204,
0.1534203,
0.123217,
0.3634809,
0.008343501,
-0.07604527,
-0.1408463,
-0.2280515,
-0.1955699,
-0.2735509,
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-0.414936,
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-0.03788355,
0.02376096,
0.01482338,
0.3545029,
0.1130957,
... |
Iatrogenic TMJ difficulty: cervical traction may be the etiology. | Patients in cervical traction for the treatment of cervical spine syndromes frequently complain that the traction makes them worse. It is possible that such patients may be suffering from TMJ symptoms. The physician treating a patient with cervical traction should consider prescribing an occlusal splint for patients wi... | 286,045 | [
-0.1882398,
0.4969037,
0.236733,
0.1326623,
0.08227155,
-0.2762694,
-0.2878769,
-0.1299783,
-0.002238574,
-0.03709376,
0.1297808,
0.06550308,
-0.1184957,
-0.38634,
-0.4296888,
-0.03385496,
-0.347033,
0.09501784,
-0.4206114,
-0.1887134,
0.06155521,
-0.08651083,
0.02806524,... |
The reproducibility of pantographic tracings on medicated and nonmedicated subjects. | Tracings were made on three patients using a modified pantographic device. The tracings were made on glass flags with wax, etched, and superimposed. The effects of body position and modification were investigated. From this research project the following can be concluded: 1. A precise method has been developed which pe... | 286,050 | [
-0.1478135,
0.01816911,
-0.3183645,
-0.3424238,
-0.1415943,
-0.2007159,
0.03533508,
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-0.2192654,
-0.06427336,
0.01528228,
0.1674502,
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-0.07510149,
0.2293331,
-0.1055473,
0.4359775,
-0.06723343,
-0.1352719,
0.07917628,
-0.1655666,
0.119266... |
Simplified Class V matrix for resin restorations. | A matrix technique and its modifications to assist in the restoration of Class V lesions occurring in the gingival third of the teeth are described. This technique is applicable for filled and unfilled restorative resins. | 286,058 | [
-0.2286679,
0.5810362,
-0.0238001,
-0.04569032,
0.1866356,
-0.2373418,
0.2416154,
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0.3273874,
0.1906831,
0.06863097,
0.3261912,
0.00362871,
0.05628909,
-0.4360992,
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-0.2566105,
-0.0478662,
-0.2359601,
-0.1189749,
0.2255794,
-0.01902279,
-0.03111673,... |
A tumor-associated organ-specific antigen characteristic of spontaneously metastatic rat mammary carcinomas. | An organ-specific tumor-associated antigen (TAA) was present in several metastatic and nonmetastatic mammary carcinomas induced in WF female rats by 3-methylcholanthrene. The level of TAA was high in 2 metastatic carcinomas tested (TMT-081 and SMT-2A) and much lower--by a factor of 50--200--in 2 nonmetastatic mammary c... | 286,100 | [
0.04886502,
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-0.7852099,
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-0.03887011,
0.1349028,
0.1550619,
0.084159,
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0.3070543,
0.2880436,
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0.006482043,
-0.3709432,
-0.2073505,
0.01447998,
0.1934354,
0.4050604,
0.1579928,
-0.3326126,
... |
Use of artificial sweeteners by cancer patients. | Current daily use of artificial sweeteners (AS) and diet drinks was evaluated for 1,862 patients hospitalized for cancer and for 10,874 "control" patients hospitalized for other conditions believed not to be associated with use of these substances. The data were derived from an ongoing survey in seven countries. For ca... | 286,112 | [
-0.2180104,
0.1721115,
-0.3557039,
0.3115259,
0.1103906,
-0.2090582,
-0.266063,
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0.0696023,
-0.04974457,
0.3232862,
0.009196664,
0.1471728,
0.08854547,
-0.1508362,
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0.02255424,
0.2947142,
-0.1719764,
0.04109291,
0.2449406,
0.1073032,
-0.3694215,
0... |
Linoleic acid inhibition of naturally occurring lymphocytotoxicity to breast cancer-derived cells measured by a chromium-51 release assay. | Long-chain unsaturated free fatty acids have been shown to inhibit the immune responses of lymphocytes in vivo and in transformation and macrophage inhibition factor assays in vitro. The purpose of this study was to test the effect of linoleic acid on naturally occurring lymphocytotoxicity in a 51Cr release microcytoto... | 286,114 | [
0.09437308,
0.01086186,
-0.2655147,
0.0591034,
0.2507922,
0.0301322,
-0.01864675,
0.1676175,
-0.02284586,
0.03439447,
-0.08334752,
0.3406306,
0.2680724,
0.01391251,
0.06991986,
-0.1145119,
-0.4076878,
0.04120313,
0.1948403,
0.431233,
0.3180066,
0.4541461,
0.06072189,
0.... |
Complement-dependent cytotoxic antitumor antibody. II. Quantitative determination of cell-bound immunoglobulin M1. | A method for the quantitative determination of rabbit IgM bound to cell surfaces has been developed. This method was based on the ability of goat IgG specific for rabbit IgM heavy chains to bind 125I-labeled protein A when bound to the antigen. With the use of this technique the production of specific IgM antitumor ant... | 286,124 | [
0.0406268,
0.004685787,
-0.07175902,
-0.2000484,
0.1141356,
-0.1192625,
0.07563715,
0.3223003,
0.06243955,
0.1211624,
-0.05997374,
0.1043341,
0.1449307,
-0.2169368,
-0.2353664,
-0.2394931,
-0.5047916,
-0.02058736,
-0.007920565,
0.1840456,
0.4622814,
-0.2536995,
-0.1596732... |
Transposon-facilitated recombination in Vibrio cholerae. | Improved Vibrio cholerae donors were constructed by introducing the ampicillin transposon, Tn1, into both the conjugative plasmid, P, and the bacterial chromosome to provide "portable regions of homology." The resulting Tfr (Transposon-facilitated recombination) donors transferred genes at high frequency from origins s... | 286,148 | [
-0.1901721,
-0.2570375,
-0.3050796,
0.09221144,
-0.1676466,
-0.1554537,
0.05151299,
-0.08187384,
0.1396463,
0.01128191,
0.3261331,
0.1853138,
-0.361595,
0.334362,
-0.3318345,
-0.3699398,
-0.5288703,
-0.2039831,
-0.06717447,
0.1791389,
0.1756539,
0.1564501,
-0.2036193,
-... |
A method which facilitates the ordering of DNA restriction fragments. | The Southern transfer technique has been used to provide a generally applicable method for ordering DNA restriction fragments. It involves electrophoresis of partially digested DNA, transfer to nitrocellulose filter paper and annealing to a 32P-labelled fragment. Only those partials containing that particular fragment ... | 286,149 | [
-0.2104822,
0.1179262,
-0.06588785,
-0.01704857,
0.2563677,
-0.1968622,
-0.1276711,
-0.03055953,
0.3937766,
0.1987044,
0.129548,
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0.1222526,
0.2144987,
-0.6169076,
-0.001531227,
-0.5839956,
-0.05313502,
-0.060709,
0.1247628,
0.2197629,
-0.03303766,
-0.1921477,
... |
The prognostic significance of radiological and symptomatic bone involvement in childhood acute lymphoblastic leukaemia. | Full skeletal survey was performed on 193 consecutive children presenting over a 6-year period with acute lymphoblastic leukaemia (ALL). A record was made of the degree of bone pain in these patients and 60 others presenting immediately prior to the availability of skeletal surveys. Bone pain was present in 76 out of 2... | 286,156 | [
0.1956039,
0.04878744,
-0.03415398,
-0.3365102,
-0.4379416,
-0.2859237,
-0.04267636,
0.08906028,
-0.2101004,
-0.1696183,
0.2037349,
-0.0657643,
-0.31901,
0.139338,
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-0.3026007,
0.05535644,
0.1968222,
0.1887136,
0.2696998,
0.420709,
0.05478453,
-0.1533788,
0.2... |
Talon cusps: a dental anomaly in the Rubinstein-Taybi syndrome. | Dental casts of fourteen cases of Rubinstein-Taybi syndrome (RTS) were studied. Two exhibited talon cusps, a dental anomaly which is rare in the normal population. Three others exhibited prominent cingula, which were interpreted as representing a tendency toward talon cusp formation. While additional cases should be ex... | 286,273 | [
-0.1256977,
0.4259101,
-0.1973008,
-0.05268784,
-0.1886198,
-0.106984,
-0.1545546,
-0.1680835,
0.0523475,
0.3666829,
0.2758752,
0.6150457,
-0.3254954,
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0.02228067,
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0.1417794,
-0.02987345,
-0.1938419,
0.4797106,
0.390287,
0.2367317,
0.... |
Angiolymphoid hyperplasia with eosinophils in oral mucosa. | Angiolymphoid hyperplasia with eosinophils is a rare, benign angioproliferative lesion with a predilection for the facial skin. A unique instance of the lesion in oral mucosa is described, and the classification, differential diagnosis, and pathogenesis of the lesion are reviewed. | 286,276 | [
-0.344524,
-0.2881946,
-0.1631214,
-0.1311196,
0.06982806,
-0.1848982,
-0.2471696,
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-0.09469053,
-0.02407454,
0.1609862,
0.06115855,
-0.007758397,
-0.2899424,
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-0.1458187,
-0.06850922,
0.1346165,
-0.2062539,
0.1110144,
0.2649234,
-0.02881... |
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