title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Analysis and comparison of root canal filling techniques. | Although much as been written about the filling of root canals, the subject is still dominated by vagueness, and there is no analytic and comparative study in the literature of the techniques in use. Furthermore, long-term results (not just for 2 or 3 years) are lacking. The inconveniences of all filling techniques, di... | 289,083 | [
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Aspects of corneal wound healing in health and disease. | The paper reviews current aspects of repair processes of the epithelial, stromal, and endothelial layers for both the normal and diseased cornea. | 289,215 | [
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A pathological study of eye involvement in acute leukemia of childhood. | The eyes of 60 children dying of acute leukemia between 1968 and 1976 at the Children's Hospital Medical Center have been examined pathologically. An attempt has been made to relate eye findings to the state of the systemic disease at the time of death. Eight of the 60 patients had leukemia retinal infiltrates and all ... | 289,224 | [
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Chromosome changes in a patient achieving complete remission in the acute phase of chronic myelogenous leukemia. | A patient with chronic myelogenous leukemia (CML) had a Philadelphia chromosome (Ph') [t(9q+;22q-)] in all cells and trisomy C in 13% of cells (later determined to be trisomy 8) at the time of diagnosis. After 21 months of intermittent treatment with busulfan, the acute phase developed with the appearance of an additio... | 289,290 | [
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Cardiomyopathy of hamster dystrophy. | Investigations of the fine structural changes observed in the hearts of cardiomyopathic hamsters at very early stages of the disease indicate that the initial changes involve the pericapillary mesenchymal cells. Other prominent features consist of hypercontraction of cardiocytes, disruption of intercalated disks, and e... | 289,324 | [
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The carcinoid tumour. | Carcinoid tumours are by no means rare. The wide range of sites in which they occur is explained by their origin from APUD cells of the neural crest. These cells migrate to all parts of the alimentary tract during embryonic life, and ultimately are found as well in various gut derivatives such as the respiratory, pancr... | 289,371 | [
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Haemangiopericytoma: problems in diagnosis and management. | Three cases of haemangiopericytoma with diverse modes of presentation are reported. The difficulties with clinical diagnosis are emphasized. There is no consensus on the best mode of treatment, and we have chosen radical surgical excision in the first instance, but have not hesitated to employ radiotherapy or chemother... | 289,377 | [
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Improved survival in young children with acute granulocytic leukemia treated with combination therapy using cyclophosphamide, oncovin, cytosine arabinoside, and prednisone. | Seven of 17 children (41%) under 5 years of age with acute granulocytic leukemia (AGL) treated with either cytosine arabinoside-cytoxan (CA-CYT) or Mini-COAP (CA-CYT with vincristine sulfate [VCR] and prednisone) have been in continuous complete remission 4 years or more. CA and CYT were each given in the dosage of 120... | 289,434 | [
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[Solubility and absorption of magnesium fluoride in the intestinal tract]. | The solubility rate of various substances was determined via solubility experiments using magnesium fluoride on various specific surfaces. This rate controls the resorption of fluorine ions from MgF2 during its passage through the intestinal tract. The solubility rate for MgF2, as for other hard-to-dissolve substances,... | 289,492 | [
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Demonstration of antibody-associated cellular cytotoxicity in patients with acute myelogenous leukemia before and after chemotherapy. | This study demonstrates that a cytotoxic serum reactivity not requiring the presence of complement appears in the sera of patients with acute myelogenous leukemia. The reaction is detected upon short-term incubation of sera in vitro with autochthonous mononuclear white blood cells from peripheral venous blood of patien... | 289,631 | [
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Sedation of the autistic patient for dental procedures. | It would be wrong to draw firm conclusions in this paper, because the methodology was highly subjective. However, the authors are of the opinion that certain conclusions can be drawn: Autistic individuals, even those with wildly aberrant behavior, can frequently receive dental treatment in a routine manner, if adequate... | 289,661 | [
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"Outpatient hyperkalemia" syndrome in renal and hypertensive patients with suppressed aldosterone production. | "Outpatient hyperkalemia" is a new clinical syndrome in which high serum potassium levels (SK) are found in the outpatient condition returning toward normal without any specific treatment after admission to the hospital. We report here of six patients with high blood pressure of various origin (chronic glomerulonephrit... | 289,714 | [
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Lymphocytic infiltration in murine tumors. | Histologic grading of the histiolymphocytic reaction in nodules of T241 or B16 murine tumors in 94 C57BL/6J mice was performed at various time intervals post-inoculation. The infiltrate occurring in the first four days was generally sparse and no significant difference was observed between two different dose control in... | 289,717 | [
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Dilemmas in diagnosis and treatment of Gilles de la Tourette syndrome. | Gilles de la Tourette syndrome (TS) is a neurological disorder which has an inordinate risk of being diagnosed as psychogenic in nature because of commonly shared behavioral symptomes with syndromes of psychological origin. An overview of TS is presented including its history, symptomatology, and treatment of choice. T... | 289,759 | [
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Testicular measurements and reproductive characteristics in stallions. | Factors affecting testicular measurements in situ and the relationships among the measurements and various reproductive characteristics were studied using data from 48 stallions. Mean values during the breeding season are provided for scrotal width, widths and lengths of individual testes, combined weight of testicular... | 289,781 | [
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Prolonged interovulatory interval after oestradiol treatment in mares. | This study was designed to test if oestradiol treatment would prevent or delay luteolysis in mares. Mares (5/group) received 0, 0.1, 1.0 or 10.0 mg oestradiol-17 beta daily from the day of ovulation until the next ovulation or for a maximum of 32 days. This treatment did not prevent luteolysis which occurred 15.8, 16.8... | 289,791 | [
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The epidemiology of contagious equine metritis (CEM) in England 1977--1978). | Following an outbreak of CEM in England during 1977 a Code of Practice was introduced to control the disease in 1978. The Code recommended a bacteriological screening programme for Thoroughbred mares and stallions and improved standards of hygiene on the stud farm. As a result of the implementation of the Code a number... | 289,806 | [
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Responses of pony mares to the agent of contagious equine metritis 1977. | Reproduction of contagious equine metritis 1977 in Pony mares was achieved with cultures of an unclassified Gram-negative coccobacillus. Infected mares developed a vaginal discharge and associated inflammatory changes of the cervix and vagina. There was evidence of variation in pathogenicity between different strains o... | 289,811 | [
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Centrifugation of stallion semen and its storage in large volume straws. | In a study of different methods of handling stallion semen for deep freezing, ejaculates were divided into 3 portions, the first of which was diluted 1:2 with lactose--egg yolk--glycerol diluent and frozen in pellet form. The second aliquot was centrifuged without any diluent and the third portion was initially diluted... | 289,825 | [
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The role of the fetal gonads and placenta in steroid production, maintenance of pregnancy and parturition in the mare. | The effects of fetal gonadectomy on steroid production and the maintenance of pregnancy in the mare were studied. Removal of the fetal gonads resulted in an immediate fall in maternal plasma concentrations of conjugated and unconjugated oestrogens whereas progestagen levels remained unchanged. Hormone profiles in mares... | 289,829 | [
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The use of synthetic prostaglandin analogue (fluprostenol) to induce foaling. | The synthetic prostaglandin (PG) analogue fluprostenol was used to induce parturition in mares and its mode of action was investigated by measuring endocrine changes before and during the induction period. Progestagens and unconjugated oestrogens showed little change during the induction period, but two different patte... | 289,831 | [
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Evaluation of deep-frozen semen in stallions. | The sperm-rich fraction of stallion semen was collected in an AV and, after dilution in an extender, was cooled to 2--5 degrees C before placing in aluminium tubes for freezing in liquid nitrogen for several hours or months. The spermatozoa in about 200 ejaculates from 36 stallions were examined to compare their surviv... | 289,832 | [
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Regulation of s-amino acids biosynthesis in Saccharomycopsis lipolytica. | ATP-sulfurylase, cysteine synthase, homocysteine synthase, arylsulfatase and beta-cystathionase in Saccharomycopsis lipolytica are repressed on the addition of methionine, homocysteine or cysteine to the growth medium. The use of appropriate mutants enabled us to demonstrate that the synthesis of these enzymes is regul... | 289,901 | [
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Accidental swallowing of an endodontic instrument. A report of two cases. | Two cases of the accidental swallowing of endodontic instruments have been reported. The instrument passed naturally through the alimentary canal within 4 days in the first case and within 2 weeks in the second case. Routine use of the rubber dam will prevent this type of accident. | 289,931 | [
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Changes in brain levels of NE and 5-HT are not responsible for attenuation of audiogenic seizures by spinal cordotomy. | Spinal cord transection affords protection from audiogenic seizures (anterior to paralysis) in 21 day-old DBA/2J mice. To test the possibility that altered brain levels of NE or 5-HT are involved in mediating this effect, whole brain levels of these amines were assayed in cordotomized and control DBA/2J mice, aged 21 d... | 289,980 | [
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Expression of oncornavirus antigens in peripheral leucocytes of patients with chronic myeloid leukaemia. | Peripheral leucocytes from 16 patients with chronic myeloid leukaemia (CML) were examined for the presence of oncornavirus p30 antigens by indirect cytoplasmic immunofluorescence. The leucocytes of 12 patients who could be kept in balance by chemotherapy proved to be negative or contained the p30 antigen of mammalian e... | 290,130 | [
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Prognostic information from EEG and ICP monitoring after severe closed head injuries in the early post-traumatic phase. A clinical and experimental study. | Neither the EEG investigations on the first post-traumatic day after severe enclosed brain injury nor evaluation of the clinical finding on the first day permit a pronosis. Measurement of intracranial pressure is necessary for monitoring of intracranial complications, but can only make a contribution to prognosis when ... | 290,187 | [
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Newest ultrastructural findings after the use of a CO2-laser on CNS tissue. | The first use of a "bloodless" knife in neurosurgery was a real revolution in surgical technique. This innovation enables us to reach non-accessable regions of the brain with less damage to the surrounding tissue. | 290,258 | [
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Functional and morphological motor regeneration after different periods of denervation and following microsurgical suture of the peroneal nerve. Experimental study in the rabbit. | The morphological and functional recovery of the peripheral nerve, motor endplate, and muscle has been studied in rabbits after different periods of denervation of the muscles and secondary suture of the supplying nerve, by electrophysiological (electromyography and electroneurography) and histological methods (electro... | 290,261 | [
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... |
Use of an incisor diagnostic triangle for evaluating incisor positions relative to the APo line. | Angular values of the upper and lower incisors to the APo line were measured in a sample of fifty subjects with clinically acceptable occlusions, ranging from 10 to 14 years of age. Correlations were high between both upper and lower incisor angulations to the APo line and the interincisal angle. The correlation was lo... | 290,278 | [
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0.3302684,
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Ready-to-eat cereals and dental caries in children: a three-year study. | In a three-year study of 145 adolescent males in a boarding school in Wisconsin, there were no statistically significant differences in dental caries experience between a group consuming phosphates added to pre-sweetened and non-presweetened ready-to-eat cereals, and the control group, or between cereal eaters and non-... | 290,650 | [
-0.3867123,
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0.2... |
Cerebrovascular changes in migraine: secondary manifestations of a circulating humoral agent? | The cerebrovascular concomitants of migraine, initial vasoconstrictriction succeeded by vasodilatation, have long been considered the primary event in the pathogenesis of headache. In recent years, certain physicochemical concomitants of the attack have been identified, all involving blood platelets: these include hype... | 290,740 | [
-0.1322949,
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Effects of portocaval anastomosis on behaviour and brain tryptophan metabolism. | The rat with portocaval anastomosis represents a convenient took for the investigation of (a) factors determining the availability of tryptophan to the brain and (b) the role, if any, that altered tryptophan metabolism may have in the development of hepatic encephalopathy. It was found that increases in brain tryptopha... | 290,742 | [
0.05458416,
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Primary tumors of the jaws in children. | Reports on primary tumors of the jaw in children are infrequent. This article reports 24 cases of primary tumors and tumor-like conditions of the jaws in children. All varieties of odontogenic and nonodontogenic tumors are seen in the jaw; fibro-osseous lesions are the most common. A possible explanation for the high i... | 290,771 | [
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Replicability of chinpoint-guidance and anterior programmer for recording centric relation. | The chinpoint-guidance technique, using an anterior programmer, as performed in this study, seems to be a replicable method of locating centric relation. Sequential registration of centric relation was repeatable in 60% of the patients studied. The average variability found in 40% of the patients of this study was abou... | 290,792 | [
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0.02885473,
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Comparative evaluation of the 30-gauge dental needle. | The results of these tests demonstrated that aspiration through 30-gauge needles is possible, but since the flow rate is so diminished its clinical application is questionable. The evaluation of the physical properties of these needles proved them to be tough, durable, and suprisingly resistant to breakage, even under ... | 290,936 | [
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0.0712... |
Nodular fasciitis of the orofacial region. | The clinical and histologic findings from a study of forty-one cases of nodular fasciitis occurring in the orofacial region are presented. These findings reveal no essential differences in the biologic conduct of nodular fasciitis, whether it occurs in the orofacial area or in its preferred sites, i.e., the extremities... | 290,944 | [
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Purification and distribution of a major protein in rat prostate that binds estramustine, a nitrogen mustard derivative of estradiol-17 beta. | A protein in rat ventral prostate cytosol that binds estramustine [estradiol 3-bis(2-chloroethyl)carbamate) was purified to homogeneity by using chromatography on DEAE-cellulose, Sephadex G-100 (superfine), octyl-Sepharose (CL-4B, and polyacrylamide gel electrophoresis. The estramustine-binding protein was found to hav... | 290,993 | [
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0.09414... |
Nucleoside triphosphate regeneration decreases the frequency of translation errors. | The addition of naturally occurring polyamines and inorganic ions to an in vitro protein-synthesizing system improved the extent and fidelity of translation. In such an optimized system, regeneration of the nucleoside triphosphates with phosphoenolpyruvate and pyruvate kinase (ATP:pyruvate 2-O-phosphotransferase, EC 2.... | 290,995 | [
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A factor in serum and amniotic fluid is a substrate for the tRNA-modifying enzyme tRNA-guanine transferase. | Q factor, a substance found in animal serum that enables cultured mammalian cells (L-M) to produce tRNA containing queuine (the base of "nucleoside Q", queuosine), has been purified to homogeneity from bovine amniotic fluid. Q factor causes the appearance of Q-containing tRNAAsp in the L-M cells cultivated in serum-fre... | 291,001 | [
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0.3481191,
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... |
Bimane fluorescent labels: labeling of normal human red cells under physiological conditions. | The bimane fluorescent labels, monobromobimane, dibromobimane, and monobromotrimethylammoniobimane, are derivatives of syn-9,10-dioxabimane:1,5-diazabicyclo[3.3.0]octa-3,6-diene-2,8-dione. They efficiently label hemoglobin (reactive thiol groups), membrane proteins, and glutathione of normal human red cells under physi... | 291,011 | [
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-0.0016... |
Tyrosine administration reduces blood pressure and enhances brain norepinephrine release in spontaneously hypertensive rats. | Administration of L-tyrosine to normotensive or spontaneously hypertensive rats reduces blood pressure. The effect is maximal within 2 hr of injection. In spontaneously hypertensive rats, a dose of 50 mg/kg, intraperitoneally, reduces blood pressure by about 12 mm Hg (1 mm Hg = 1.33 x 10(2) pascals); a dose of 200 mg/k... | 291,018 | [
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... |
Proton magnetic resonance studies of cholinergic ligand binding to the acetylcholine receptor in its membrane environment. | Proton magnetic resonance has been used to monitor binding of choline, a known partial agonist, to acetylcholine receptor-enriched membrane preparations from Torpedo californica electroplax. The interaction between choline and receptor led to a broadening of the resonance of the choline methyl groups and this effect wa... | 291,025 | [
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0.... |
Adenine aminohydrolase: occurrence and possible significance in trypanosomid flagellates. | Adenine aminohydrolase (EC 3.5.4.2) from four species of Leishmania and from Crithidia fasciculata was examined for specific activities, affinity for substrate (adenine), and stability to heat. All were found to be strongly and non-competitively inhibited by both coformycin and deoxycoformycin, two tight-binding inhibi... | 291,031 | [
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Production and characterization of a monoclonal antibody to chicken type I collagen. | We have shown that lymphocyte-myeloma cell hybridization can be used to produce large amounts of extremely high-titer specific antibodies against type I collagen, a macromolecule normally of low immunogenicity. In a passive hemagglutination assay the antibody had a high titer against chicken type I collagen but showed ... | 291,035 | [
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... |
[Dental amalgam corrosion]. | Corrosion of amalgam is a natural phenomenon of the behaviour of a metallic substance in the oral environment. Corrosion is a process in which we have a anodic reaction resulting in a loss of electrons and a cathodic reaction resulting in a captation of electrons. One single amalgam restoration in a electrolitic enviro... | 291,078 | [
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[Kaposi's disease (author's transl)]. | A case of Kaposi's disease is reported with a lesion in the buccal mucosa, and the history, classification, signs and symptoms, and treatment of this disease are described. | 291,111 | [
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Fanconi's anaemia developing erythroleukaemia. | A 15-year-old boy with Fanconi's anaemia (FA) for 10 years developed acute erythroleukaemia. During the leukaemic phase, granulopoietic stem cells (CFUc) were absent from his bone marrow and blood, but proliferation and differentiation of bone marrow cells could be seen in semipermeable diffusion chambers in vivo, and ... | 291,120 | [
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[Dental caries and pregnancy]. | In a Berlin population comprising 588 women aged between 18 to 50 years, no increase of the DMF index was observed in multiparae. Nevertheless, complete dental treatment was stated in them less often. | 291,196 | [
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Hemodilution and oxygen transport to tissue in shock. | Shock was induced in sixty dogs by laparotomy, splenectomy and exteriorization of the small intestine for three hours. Resuscitation following different plasma substitutes was assessed by measuring hemodynamic parameters (mean arterial blood pressure, plasma volume, oxygen consumption, cardiac output and hematocrit). T... | 291,260 | [
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Child-environment supervisors--a new strategy for prevention of childhood accidents. | This paper is a provisional report from an ongoing field experiment in Uppsala, Sweden, with the aim to reduce the number of serious childhood accidents. Groups of parents have been systematically trained to function as child-environment supervisors. The experiences have been very positive so far. The child-environment... | 291,281 | [
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Dealing with suspicions of malformation frequency increase. Experience with the Swedish register of congenital malformations. | Strategies in dealing with data obtained from malformation monitoring based on experiences with the Swedish monitoring systems, operating since 1965 (Register of Congenital Malformations) and 1973 (Medical Birth Register) are discussed. The importance of checking data that have sounded an alarm is stressed. Experience ... | 291,291 | [
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Studies on vagal activation of gastric acid secretion in man. | Vagal activation produces a gastric acid secretory response by direct nervous stimulation of the parietal cell area and, at least in dogs, by gastrin released mainly from the antrum. In duodenal ulcer (DU) patients antrectomy reduces the acid response to sham feeding slightly more than the maximal acid output in respon... | 291,298 | [
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0.3003882... |
55 Nitinol wire: force developed as a function of "elastic memory". | Closing spaces is done either by translation of the edgewise brackets over an archwire or by the use of closing loops of some common design. This investigation suggests the concept of the further refinement of the "wire rubber band" as a means of closing spaces. Advantages of such a wire hypothetically would be to leve... | 291,389 | [
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Mental symptoms and electrolyte imbalance. | A 75-year-old woman on long term diuretic therapy presented with depression. She was found to have hyponatraemia and hypochloraemia. There was no improvement in her condition with antidepressant medication but she responded promptly to cessation of spironolactone and prescription of potassium chloride. | 291,429 | [
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0.1039285... |
Chromosomes and causation of human cancer and leukemia. XXXIV. A case of "hypereosinophilic syndrome" with unusual cytogenetic findings in a chloroma, terminating in blastic transformation and CNS leukemia. | A 47-year-old white male developed massive hepatosplenomegaly, a pleural effusion, leucocytosis, and a left parasternal mass following a relatively symptom-free persistent hypereosinophilia for about 5 years. Bone marrow aspiration and biopsy and peripheral blood differential showed eosinophilia and a shift to the left... | 291,466 | [
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0.158012,
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0.07832829,
0.2532968,
0.2240216,
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0.... |
Cytotoxic thresholds of vincristine in a murine and a human leukemia cell line in vitro. | L1210 murine leukemia and CEM human lymphoblastoid leukemia cells were exposed to vincristine sulfate in vitro. The response of these cell lines to this agent was measured by the colony-forming ability of L1210 cells in soft agar and inhibition of growth of CEM in suspension culture. Incremental increases of vincristin... | 291,476 | [
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0.03... |
Clinical and pharmacologic studies with adriamycin-DNA complex in children with malignant disease. | During the last 4 years, we have studied the adriamycin-DNA complex originally developed by Trouet and co-workers (1972). This paper summarizes the results of our pharmacologic and clinical studies. The complex is taken up by cells through an adsorptive pinocytosis, with DNA as the binding molecule. Excess DNA prevents... | 291,502 | [
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-... |
Peer review for nonphysicians. | The inclusion of nonphysician health care practitioners in hospital quality assurance programs is being called for by the new JCAH standards and PSRO regulations/PSRO guidelines require that nonphysicians be reviewed by peers. | 291,568 | [
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0.04852427... |
Analysis of genetic control of chylous ascites in ragged mice. | Chylous ascites is a disorder visible as a white fluid in the peritoneal cavity of suckling mice. It is due to inadequate lymphatic drainage from the small intestine. An initial genetic study showed it to be a pleiotropic effect of ragged, Ra. There were four main studies. These involved seven major mutants segregating... | 291,594 | [
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0.0985937... |
Multiple skeletal metastases of osteogenic sarcoma in a dog. | A 9-year-old male German Shepherd Dog with osteogenic sarcoma involving the right humerus was treated by scapulohumeral disarticulation and adjuvant chemotherapy. Doxorubicin was used, at a dosage of 30 mg/m2 of body surface. Chemotherapy was unsuccessful, and 4 months after surgery, the dog developed multiple metastas... | 291,598 | [
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Benign cementoblastoma. | A case of benign cementoblastoma in a 20-year-old man has been reviewed. The lesion was typical and was associated with the mandibular right first molar. The patient initially reported symptoms related to that tooth. Radiographically, the lesion was 1.5 cm in diameter and had a peripheral radiolucent border. Histopatho... | 291,659 | [
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0.05338996,
0... |
Effects of cyanate, thiocyanate, and amygdalin on metabolite uptake in normal and neoplastic tissues of the rat. | Thiocyanate was found to resemble cyanate in its inhibitory effects on [3H]thymidine incorporation and the uptake of [32P]phosphate and [3H]amino acids in transplanted tumors of the BUF rat. The capacity to inhibit metabolite uptake in hepatomas and a colon tumor under conditions in which uptake was unchanged or increa... | 291,753 | [
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0.2242319,
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Phosphorylase isoenzymes in normal and myophosphorylase-deficient human heart. | Phosphorylase isoenzymes were studied by acrylamide-slab electrophoresis in normal tissues and in the heart of a child with a fatal infantile form of myophosphorylase deficiency. Of the three bands present in normal human heart, two were missing in the patient's heart: the slow "muscle" isoenzyme and the intermediate b... | 291,791 | [
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0.017... |
Rubber-base impression material as a foreign body. Report of a case. | This case history describes the problems that may arise when foreign materials are injected subperiosteally during a dental procedure. The diagnosis might have been more difficult if the material had not been sufficiently radiopaque to be detected on a radiograph. | 291,864 | [
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0.1414017... |
Role of mammalian RNase inhibitor in cell-free protein synthesis. | Addition of the human placental RNase inhibitor at 10 mu/ml to a mixture of wheat germ extract and translation components, prior to the addition of mRNA from dog pancreas or influenza virus-infected cells, resulted in a significant increase in the yield of proteins synthesized. Analysis of the translation products by s... | 291,894 | [
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Translation and characterization of messenger RNAs in differentiating chicken cartilage. | Total RNA, prepared from chicken limb bud cultures undergoing differentiation to cartilage, has been translated in a wheat germ cell-free protein-synthesizing system. Antibodies against chondroitin sulfate proteoglycan core protein immunoprecipitate a single component which migrates as a protein of 340,000 daltons in s... | 291,903 | [
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Peptide maps comparing subunits of maize chloroplast and type II nuclear DNA-dependent RNA polymerases. | Both one- and two-dimensional peptide mapping techniques have been used to compare the 180-kilodalton subunits from maize chloroplast and type II nuclear DNA-dependent RNA polymerases (nucleosidetriphosphate:RNA nucleotidyltransferase, EC 2.7.7.6). Despite their similar molecular mass, these 180-kilodalton subunits are... | 291,906 | [
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Synthesis and turnover of globin mRNA in murine erythroleukemia cells induced with hemin. | When murine erythroleukemia (MEL) cells are induced with hemin, they carry out several early functions of the erythroid program. However, they do not become committed to terminal differentiation nor do they become benzidine positive. This is in contrast to MEL cells induced with dimethyl sulfoxide (Me(2)SO) which under... | 291,931 | [
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0.07235035,
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Long-term culture of capillary endothelial cells. | Capillary endothelial cells from rats, calves, and humans, have been carried in long-term culture. Bovine capillary endothelial cells have been cloned and maintained by serial passage for longer than 8 months. This prolonged culture was accomplished by using tumor-conditioned medium, gelatin-coated plates, and a method... | 291,937 | [
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Gene mutations (de novo) found in electrophoretic studies of blood protein of infants with anomalous development. | Twelve proteins of enzymic and nonenzymic nature in blood samples of infants that deviate from the average population in physical development (50 premature and 177 full-term infants with rough and multiple developmental defects) were studied by electrophoresis in polyacrylamide and starch gels. The control group consis... | 291,938 | [
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-... |
Manganese and zinc blockade of enzyme induction: studies with microsomal heme oxygenase. | Heme oxygenase (decyclizing) [heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating), EC 1.14.99.3] is greatly induced in the kidney by the administration of nickel or tin. Manganese, when administered simultaneously with nickel or tin in an equimolar amount, substantially inhibited the indu... | 291,950 | [
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beta-Endorphin: analgesic and hormonal effects in humans. | The pharmacokinetics and the hormonal, analgesic, and behavioral effects of several doses of human beta-endorphin were evaluated after intravenous administration to three patients and intracerebroventricular administration to one patient with pain caused by cancer. These effects were compared to the hormonal effects of... | 291,954 | [
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In vitro maturation of mesencephalic dopaminergic neurons from mouse embryos is enhanced in presence of their striatal target cells. | Long-term survival of mesencephalic and striatal cells from mouse embryos in dissociated primary cultures is described. Catecholaminergic neurons in mesencephalic culutres were identified histochemically and by measuring [3H]dopamine uptake and synthesis from [3H]tyrosine. According to experiments using specific inhibi... | 291,955 | [
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1H nuclear magnetic resonance investigation of flexibility in DNA. | In this paper we report successful observations of proton NMR spectra of native double helical salmon sperm and calf thymus DNA of various lengths. Measurements of the linewidths arising from proton--proton dipolar interactions are used to obtain information about the dynamic behavior of DNA helices in solution. Depend... | 291,958 | [
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... |
Differential activities of glycolipid glycosyltransferases in Tay-Sachs disease: studies in cultured cells from cerebrum. | Four different glycolipid:glycosyltransferase activities involved in the biosynthesis in vitro of gangliosides and blood group-related glycosphingolipids have been tested in a simian virus 40-transformed glial cell culture derived from the cerebrum of a fetus with Tay-Sachs disease (TSD). The TSD cultured brain cells c... | 291,963 | [
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Determination of fluoride and chlorhexidine from chlorhexidine/fluoride-containing dentifrices. | The intention of the present experiment was to study the effects of a possible interaction between fluoride and chlorhexidine when both agents were incorporated in the same vehicle. The amount of fluoride extractable from dentrifrices containing 0.1% NaF and the fluoride ion activity were not reduced by the addition of... | 292,158 | [
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... |
Effect of long-term administration of fluoride on plasma fluoride and calcium in relation to forming enamel and dentin in rats. | Three groups of 1-month-old rats were kept on water containing 0.2, 56.5 and 113 parts/10(6) F-, respectively, for a period of 2 months. These groups were set up in order to study the relationship between long-term administration of high doses of waterborne fluoride, plasma values of fluoride and calcium and changes in... | 292,162 | [
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... |
Disseminated cryptococcosis with ocular involvement. | A case of disseminated cryptococcosis with extensive ocular involvement is reported. The patient had pulmonary, meningeal, cerebral, cutaneous, lymph node, renal, adrenal and thyroid lesions, as well as granulomatous endophthalmitis. | 292,387 | [
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0.07385762,
... |
The immunobiology of placentation. | A review of the current theories on the nature of the placental allograft and the evolution of placentation in the presence of a cellular immune response highlights the inability of current hypotheses to explain the success of both invertebrate and vertebrate placentation. Only one theory -- "the anatomical separation ... | 292,417 | [
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-0.07066... |
Proliferating ovarian "epithelial" tumours: a clinico-pathological analysis of 144 cases. | In a 25-year period, 144 patients with proliferating epithelial ovarian tumours were treated at the King George V Memorial Hospital. These tumours were classified according to the World Health Organisation (WHO) Histological Classification of Ovarian Tumours and subsequently divided into 4 grades of proliferation, agai... | 292,420 | [
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0.5... |
A simple operation for postcoital urethrotrigonitis in women. | Definitive treatment of postcoital urethrotrigonitis, or "honeymoon cystitis", as it is commonly called, has only been paid serious attention since 1967. It has been suggested (O'Donnell, 1959) that the introduction of bacteria into the urethra is more likely when the urethra assumes a relatively hypospadiac position d... | 292,430 | [
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0.07933666,
0.09975939... |
t(8;14) translocation in a Burkitt's type of lymphoblastic leukaemia (L3). | Cytogenetic findings on five patients with ALL Burkitt's type are reported. A t(8;14) (q23;q32) translocation identical to that found in Burkitt's lymphoma cells was found in each case. The relationship between ALL, L3 type and Burkitt's tumours is discussed. | 292,454 | [
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Studies on the mechanism of action of hexamethylene bisacetamide, a potent inducer of erythroleukemic differentiation. | Hexamethylene bisacetamide (diacetyldiamino hexane) is a potent inducer of erythroid differentiation in murine erythroleukemia cells. Hexamethylene bisacetamide and the closely related pentamethylene bisacetamide were synthesized with radioactive labels in various portions of the molecule and the uptake, metabolism, an... | 292,456 | [
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-0.2332829,
0.01080818,
-0.3088111,
0.4359427,
0.3102778,
0.2569424,
-0.1146229,
0.... |
Quantitation of human thymus/leukemia-associated antigen by radioimmunoassay in different forms of leukemia. | Using a radioimmunoassay, increased levels of a human thymus/leukemia-associated antigen (HThy-L) have been detected in leukemic cells and plasma from most patients with E-rosette-positive acute lymphoblastic leukemia (ALL) and a number of patients with E-rosette-negative ALL, acute myeloblastic leukemia (AML), acute m... | 292,458 | [
-0.115937,
-0.1667781,
-0.2715102,
-0.3136374,
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-0.238652,
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0.3057725,
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0.3946529,
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0.02723377,
-0.324585,
-0.000178436,
0.4998824,
-0.04303806,
-0.1214466,
... |
[Marginal cleft and solubility]. | Studies of extracted teeth showed that, when the width of the interval is increased by 0.1 mm, the depth of the interval enlarged an average of 0.067 mm. It would seem that, in terms of cement caries, the attachment cement loosens more quickly under the effect of carious processes. The loss of substance is less when th... | 292,585 | [
0.1611255,
0.2239233,
0.04497262,
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0.1021319,
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0.1266314,
0.06734212,
0.3178564,
0.3239601,
0.1626974,
0.1561074,
0.123... |
[Heat expansion of composite resins stored in water]. | Thermal expansion coefficients between 10 C and 60 C were determined in 10 degree increments with 10 plastic filling materials and two plastics used for protheses (3 specimens each). The coefficients became larger as the temperature increased. The composites with 20 to 60.10(-6)/C are closest to the thermal expansion c... | 292,589 | [
-0.2743217,
0.2947485,
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0.003489857,
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0.3335205,
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0.1072589,
0.5140738,
0.1212003,
-0.06674132,
... |
[Prosthetic rehabilitation after loss of the tongue]. | By fitting defect prosthesis, the act of swallowing, normalization of speech, and improvement in mastication were restored in many patients with tongue loss. The defect prosthesis also served to increase the volume and mobility of the tongue. | 292,592 | [
-0.1433405,
0.1118877,
-0.005694116,
0.1060608,
0.1967901,
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0.2450002,
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-0.3122312,
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0.242275,
-0.1845218,
0.140643... |
Factors influencing capacity to judge direction of tactile stimulus movement on the face. | The influence of stimulus velocity and traverse length on a subject's ability to indicate direction of brush movement across perioral skin was determined using a forced-choice procedure. The data show that correct identification of brush direction increases with traverse length and is optimal for velocities between 3 a... | 292,673 | [
-0.09135544,
-0.1835663,
-0.4170573,
-0.05178667,
0.3890492,
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0.07530455,
0.01427891,
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0.1325817,
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-0.2126807,
-0.5732356,
0.04312113,
-0.2906183,
0.1954247,
0.2488384,
0.08440341,
0.0233... |
Modification by salivary pellicles of in vitro enamel remineralization. | The effectiveness of inorganic calcifying solutions to remineralize enamel with subsurface demineralization decreased with saliva pre-treatments conducive to the formation of enamel pellicles. Greater reductions in remineralization rates occurred with longer pellicle formation times. It is suggested that enamel pellicl... | 292,675 | [
-0.1813479,
0.04338165,
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0.01093787,
0.2350155,
0.0917645,
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0.2961507,
0.1123735,
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-0.2645442,
-0.1611542,
-0.1495801,
-0.01195084,
0.09690551,
-0.073038... |
Clinical performance of a gold-containing amalgam. | In this study, the clinical performance (marginal fracture) of a gold-containing amalgam was compared to five traditional gamma 2-containing amalgams and one non-gamma 2 amalgam. The results showed that the performance of this gold-containing amalgam was bettered by the non-gamma 2 amalgam and four of the five gamma 2-... | 292,678 | [
-0.610434,
0.2533081,
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0.07307594,
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0.02471557,
0.1687101,
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0.1872205,
0.1947902,
0.09029751,
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0.04608945,
0.004537293,
-0.3356953,
0.06292669,
0.3540136,
-0.1394296,
0.1565692,... |
Amelogenesis imperfecta: local hypoplastic type with pulpal calcification. | A case report of a patient with local hypoplastic type of amelogenesis imperfecta is presented. Developmentally absent canines and unerupted teeth in the anterior maxilla and calcifications in the apical third of the pulp chambers of the molars were noticed and discussed. A family history was analyzed as consistent wit... | 292,722 | [
-0.3074619,
0.2172694,
0.05345803,
0.09576543,
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0.08266844,
0.1623705,
0.3996795,
0.3194376,
-0.3150586,
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0.07135073,
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-0.5903481,
0.5090688,
0.1606249,
0.02909281,
0.... |
Multiple basal cell carcinomas and keratocysts - the Gorlin and Goltz syndrome. | This paper is based on our experience with the Gorlin-Goltz syndrome and on data from 14 patients of the Nordwestdeutsche Kieferklinik in whom this disorder was detected, treated and followed up. A clinical concept has been produced, with a diagnostic check list including a genetic and a dermatological routine work up ... | 292,745 | [
-0.03867402,
-0.04385713,
-0.08583909,
-0.4307918,
0.3105382,
-0.3505978,
-0.1474975,
0.07475797,
0.220972,
0.5495011,
0.2188572,
-0.1087344,
0.07755115,
-0.1117161,
-0.3790034,
-0.132961,
-0.3658889,
0.0502326,
0.1891472,
0.03203658,
0.4176751,
0.2686949,
0.1047245,
0.... |
Mandibular movements of young adults recorded by intraorally placed light-emitting diodes. | Mandibular chewing movements of 10 young adults were registered with LED. The registrations were performed manually, and the following observations were made: 1. The mean cycle duration was reduced from 1.12 seconds for cycle 1 to 0.76 second for cycle 16. 2. The duration of the opening phase appeared to be shorter tha... | 292,778 | [
-0.1463099,
0.5191197,
-0.3151008,
0.1176364,
0.1541143,
-0.3591856,
-0.3827799,
-0.04061773,
0.02585561,
-0.382789,
0.06925116,
-0.147201,
-0.2111894,
-0.3911394,
-0.700123,
-0.2540361,
-0.6293538,
0.2335484,
0.1147413,
-0.208073,
0.2354071,
-0.02263802,
-0.1631378,
0.... |
Linkage studies in hereditary angio-oedema. | The locus for hereditary angio-oedema must lie well outside the limits of the HLA complex. Linkage tests with 16 marker loci gave no hint of linkage. In particular, close linkage is excluded for C6, PGM1 MNSs, Gm, Rh, Km, Hp, and ABO. | 292,793 | [
-0.1574074,
0.04797278,
0.1417468,
-0.1459297,
-0.05287207,
0.01070991,
0.2446206,
-0.114805,
-0.06267603,
0.1851744,
-0.1099666,
0.397606,
0.095621,
-0.2826398,
-0.7109029,
-0.01697495,
-0.08573736,
0.2705584,
0.05203598,
-0.005657211,
0.2334171,
0.01075403,
-0.2165857,
... |
Murine leukemia virus-associated cell surface antigens in rats neonatally infected with Gross murine leukemia virus. | The inoculation of newborn W/F, Lew, AS and DA rats with Gross murine leukemia virus (G-MuLV) resulted in the prompt appearance of cells with viral protein antigens (VPA) on their surfaces. These were first found in the bone marrow and spleen and later in the thymus gland. As the animals developed, the VPA-positive pop... | 292,817 | [
0.1868188,
-0.2826362,
-0.3058078,
-0.2479617,
0.1678528,
-0.2085475,
0.003419237,
0.1386969,
-0.02284665,
0.1577642,
0.02490084,
0.2869401,
0.06457534,
0.09616306,
-0.1768626,
-0.3274796,
-0.5026951,
0.07275523,
0.2381946,
-0.001947312,
0.2808873,
-0.02555955,
-0.2150593... |
Ribosomal proteins of the dimorphic fungus, Mucor racemosus. | Ribosomal proteins of the dimorphic fungus Mucor racemosus were isolated and characterized by 2-dimensional gel electrophoresis. Proteins from ribosomes of the yeast and mycelial phase were compared, and were found to be qualitatively indistinguishable. The only consistent difference in the patterns of proteins was in ... | 292,824 | [
0.03765275,
-0.2195888,
-0.09048442,
-0.1160483,
-0.113374,
0.005757678,
0.275107,
0.1899399,
0.1760279,
0.08601259,
-0.01397742,
-0.0312976,
-0.4142958,
-0.03513079,
0.03745031,
0.1708923,
-0.06964242,
-0.159873,
0.289553,
-0.1518674,
0.313277,
0.09651777,
-0.1132393,
... |
A case of advanced abdominal pregnancy. | A case of advanced abdominal pregnancy is described, with survival of both the mother and a normal infant. Reasons for the failure to establish the correct preoperative diagnosis are discussed. | 292,854 | [
-0.1111879,
-0.1016917,
-0.357431,
-0.2662371,
0.1453293,
-0.1452644,
-0.2713532,
-0.3709856,
0.1966006,
-0.1588861,
0.1431512,
0.0330667,
-0.01066594,
0.1332022,
-0.1520141,
-0.2960795,
-0.4996264,
0.105671,
-0.2491802,
0.04589452,
-0.03931826,
0.09971557,
0.04156448,
... |
Infant circumcision. | A prospective one year study of a birth cohort of 1262 infants indicates that the rate of infant circumcision has decreased substantially and is now about 25 percent. Most are performed at parental request and for family and traditional reasons rather than medical indications. | 292,883 | [
0.04924266,
0.04851487,
-0.1470047,
0.07710814,
0.01234586,
-0.2309482,
-0.373635,
-0.09199943,
-0.01605402,
-0.09576286,
0.1410689,
-0.03799077,
0.1333599,
-0.08052354,
-0.0677439,
-0.1464258,
-0.1686645,
0.09046704,
-0.1354346,
0.01513318,
0.4383438,
0.07666931,
-0.0773... |
Eczema herpeticum: atopic dermatitis complicated by primary herpetic gingivostomatitis. | Various aspects of eczema herpeticum are discussed, and a case of eczema herpeticum secondary to atopic dermatitis complicated by primary herpetic gingivostomatitis in a young adult is presented. The lesions cleared, and the patient was discharged after treatment via a multiphasic approach directed at the management of... | 292,955 | [
-0.07838105,
0.1756482,
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-0.30087,
0.05883405,
-0.1533747,
-0.09824421,
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-0.1324124,
-0.0464635,
0.2001392,
0.1767852,
-0.1114595,
-0.03334076,
-0.2268525,
0.0131172,
-0.3149621,
0.1890588,
-0.1266453,
-0.1089584,
-0.2671202,
0.3037362,
0.06968949,
... |
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