title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Prostaglandin synthesis in isolated rat kidney glomeruli. | Isolated rat kidney glomeruli converted octatritiated arachidonic acid to several prostaglandins whose production was inhibited by meclofenamate. These were, in order of decreasing abundance, prostaglandin F2 alpha, prostaglandin E2, 6-oxo-prostaglandin F1 alpha, thromboxane B2, and prostaglandin D2. These products wer... | 286,300 | [
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Models of fibrin. | High-symmetry models of the fibrin fiber are proposed that reproduce the experimentally observed high specific volume of the fiber. The models meet the following criteria: fibrin monomers have the three-domain Hall and Slayter structure; the monomers are arranged lengthwise into strands (protofibrils) in which successi... | 286,304 | [
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Nerve growth factor-induced transformation of immature chromaffin cells in vivo into sympathetic neurons: effect of antiserum to nerve growth factor. | Pre- and postnatal injections of nerve growth factor, initiated with one dose on day 17 of gestation and continued after birth with daily subcutaneous administration until day 10 of life, produce massive transformation of chromaffin in sympathetic nerve cells in the rat adrenal medulla. Large sympathetic ganglia, absen... | 286,308 | [
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Retrograde transport of nerve growth factor in chicken embryo. | We have demonstrated retrograde transport of nerve growth factor to the dorsal root ganglia in the chicken embryo. Polyacrylamide gel pellets impregnated with 125I-labeled nerve growth factor were implanted subcutaneously in the leg of stage 36 (10-day) chicken embryos. The embryos were killed 8 hr after implantation a... | 286,335 | [
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Biochemical effects of and bacteriological response to sugar substitutes in the oral environment. | The problems of the biochemical effects of sugar substitutes and bacteriologic response to such substitutes in the oral cavity may fill a whole book. Therefore, considerable restrictions in the presentation are necessary. Noncaloric sweeteners and additives are not utilized by the oral microorganisms for metabolism and... | 286,372 | [
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New hypothesis of developmental anomalies of the anterior chamber associated with glaucoma. | The group of congenital and developmental anomalies of the anterior chamber associated with increased intraocular pressure has been difficult to interpret from an embryologic perspective which would take into account the ocular defects as well as associated systemic abnormalities. A new hypothesis is presented which su... | 286,450 | [
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Progeny of survivors of acute lymphocytic leukemia. | Eight successful pregnancies and one spontaneous abortion have been observed in 5 women belonging to a group of 212 Nordic children who had their antileukemic therapy discontinued before January 1, 1978. Furthermore a young leukemic man was the father of a healthy child after 4 years of intensive cytostatic therapy. No... | 286,498 | [
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Technical aspects of single transducer echocardiography. | In echocardiographic recordings optimal amplification and A-mode control should be used. In wall motion analysis greater accuracy is obtained by utilization of enlarged display scale. When these technical aspects are taken into consideration accurate and reproducible recordings are obtained. | 286,523 | [
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Combined orthodontic-surgical correction of moderate mandibular deficiency. | Carefully planned, coordinated, and executed orthodontic and surgical treatment is a viable alternative to traditional orthodontic treatment of patients with moderate mandibular deficiency. Recognition of their clinical manifestations is essential to distinguish between relative and absolute mandibular deficiency. If a... | 286,551 | [
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A comparative cephalometric study of Class II, Division 1 nonextraction and extraction cases. | 1. Cephalometric tracings of thirty Class II, Division 1 cases without extraction and twenty-five Class II, Division 1 cases with extraction were evaluated and statistically compared by means of the overbite depth indicator (ODI) and the anteroposterior dysplasia indicator (APDI). 2. The mean ODI in the nonextraction g... | 286,568 | [
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Beneficial effects of hepatitis in patients with acute myelogenous leukemia. | Of 50 consecutive patients admitted with acute myelogenous leukemia, 30 developed complete remissions on antileukemic therapy. Nineteen of the 30 repeatedly had elevated serum glutamic oxalacetic transaminase (SGOT) concentrations 3 to 14 weeks after the start of therapy. Patients with SGOT elevations had a significant... | 286,572 | [
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A survey of the elemental composition of alloy for dental amalgam. | Analyses of 51 alloys (conventional, 41, and high-copper, 10) currently available in Australia were made. A rapid and precise procedure was developed that relied on wet-way methods for silver and tin while copper, zinc, mercury, indium and low-level constituents, such as lead, cadmium and antimony, were determined by a... | 286,592 | [
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Preparation of uniform cylindrical amalgam test pieces. | A simple die made from inexpensive materials for use in the preparation of uniform test pieces of amalgam is described. | 286,594 | [
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[Normal and modified nucleobases excreted in urine of patients with chronic nyeloproliferative disorders (author's transl)]. | The qualitative and quantitative analysis by high performance liquid chromatography of the normal and modiefied nucleobases excreted in urine represents a new and versatile tool, especially in oncology. The excretion of 2 normal (adenine, guanine) and 4 modified nucleobases (methylated guanine derivatives) in urine was... | 286,610 | [
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The concentrations of free fatty acids, triglycerides and phospholipids in submandibular salivary glands of rats in essential fatty acid deficiency. | EFA deficiency was created in young weanling rats by feeding for 16 weeks purified diets containing 0% fat or 7% hydrogenated coconut oil (HCO). Control rats were fed similar diets which contained 7% corn oil or 5% HCO + 2% corn oil. Submandibular salivary gland (SMSG) lipids were extracted and analyzed for the concent... | 286,707 | [
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False aneurysm of the cheek: report of two cases. | Two cases of false aneurysm that occurred in the cheek are described. The clinical and histological findings indicated the lesions were due to hemorrhage caused by blunt and iatrogenic trauma. In addition, a continuous supply of blood into the cystic spaces through small veins or dilated capillaries in the wall was pos... | 286,768 | [
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Diagnosis and treatment of pansinusitis: report of case. | A case of acute pansinusitis with the complication of orbital cellulitis has been described. The patient initially had pain around the maxillary right first molar. Accurate diagnosis allowed for prompt, vigorous treatment, culminating in surgical intervention. The need for dental and oral surgical practitioners to be t... | 286,782 | [
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Effect of dietary alfalfa, pectin, and wheat bran on azoxymethane-or methylnitrosourea-induced colon carcinogenesis in F344 rats. | The effect of dietary alfalfa, pectin, and wheat bran on colon carcinogenesis was studied in female inbred F344 rats. Weanling rats were fed semipurified diets containing 0 or 15% alfalfa, pectin, or wheat bran. At 7 weeks of age, all animals except controls were given azoxymethane (AOM) sc at a dose rate of 8 mg/kg bo... | 286,824 | [
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Mitochondrial DNA from Podospora anserina. II. Properties of mutant DNA and multimeric circular DNA from senescent cultures. | Mitochondrial (Mt) DNA from mitochondrial mutants of race s Podospora anserina and from senescent cultures of races s and A was examined. In mutants, we observed that fewer full length circles (31 mu) were present; instead, smaller circles characteristic for each mutant studied were found. Eco R1 digestion of these mut... | 286,868 | [
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The nucleotide sequence of the region surrounding the replication origin of an R100 resistance factor derivative. | The replication origin of a group of small plasmids derived from R100 was previously determined by electron microscopy (Ohtsubo et al., 1977). This region was subjected to extensive restriction enzyme analysis and the nucleotide sequence of the region containing the replication origin was determined using the Maxam and... | 286,869 | [
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Acute nonlymphocytic leukemia: expression in cells restricted to granulocytic and monocytic differentiation. | Two patients with acute nonlymphocytic leukemia who were heterozygous for the X-chromosome-linked enzyme glucose-6-phosphate dehydrogenase were studied to determine the number and type of cells in which the disease arises. Both type A and B isoenzymes were found in normal tissues, but the myeloblasts showed only one en... | 286,882 | [
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Regulation of DNA replication in S phase nuclei by ATP and ADP pools. | Synchronized 3T6 (mouse fibroblast) ghost monolayers (isolated nuclei) were utilized to study the effects of ATP and ADP levels on DNA replication in vitro. A system yielding discontinuous semiconservative DNA replication (without any detectable repair) in synchronized S phase nuclei has been developed. Lack of initiat... | 287,004 | [
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Presence of chondroitin sulfate in the neuronal cytoplasm. | The distribution of glycosaminoglycans and glycoproteins has been studied in cytoplasmic and particulate fractions of neurons isolated in bulk from rat cerebrum. Lysis of the neurons in 25 mM sodium phosphate buffer at pH 7.5 released 20% of the protein and over 90% of the lactate dehydrogenase in a soluble form. Eight... | 287,011 | [
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In vitro regulation of DNA-dependent synthesis of Escherichia coli ribosomal protein L12. | The DNA of the transducing phage lambdarifd18 contains, among others, the genes for the ribosomal proteins L11, L1, L10, and L12 and the beta and beta' subunits of RNA polymerase (nucleosidetriphosphate:RNA nucleotidyltransferase, EC 2.7.7.6). In a coupled in vitro protein-synthesis system, lambdarifd18 DNA directs the... | 287,012 | [
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Conditions for inhibiting and enhancing effects of the protease inhibitor antipain on x-ray-induced neoplastic transformation in hamster and mouse cells. | Using cultured normal hamster embryo cells and the heterploid mouse C3H cell line 10T1/2, clone 8, we have studied the effect of the protease inhibitor antipain on x-ray-induced neoplastic transformation. We found in both cell systems that, while there was no effect on cell survival as compared to irradiated controls, ... | 287,021 | [
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Migratory patterns of cloned neural crest melanocytes injected into host chicken embryos. | Cloned quail melanocytes grown in tissue culture for 8 days or more were injected into 2 1/2-day-old chicken embryos. The pigment cells were placed directly into the somitic lumen by means of an injection micropipette. This technique for introducing marked neural crest cells into host embryos causes far less damage tha... | 287,025 | [
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Biliary transport of IgA: role of secretory component. | Biliary transport of rat immunoglobulin was studied by perfusion of isolated rat liver with blood containing radiolabeled immunoglobulin. Transport to bile was selective for polymeric IgA. Between 15 and 27% of polymeric IgA was transported from blood to bile during a 210-min perfusion period, and approximately 60% of ... | 287,039 | [
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Measles and subacute sclerosing panencephalitis virus proteins: lack of antibodies to the M protein in patients with subacute sclerosing panencephalitis. | Studies on the immunoprecipitation of the proteins of several different measles and subacute sclerosing panencephalitis (SSPE) virus strains from lysates of infected cells have revealed a relative lack of antibodies to the nonglycosylated viral membrane protein (M) in the sera of patients with SSPE, in contrast to a hi... | 287,042 | [
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-0.0960... |
Further studies on the mode of action of the heme-controlled translational inhibitor: stimulating protein acts at level of binary complex formation. | Previous work has shown that (i) at physiological concentrations of eukaryotic initiation factor 2 (eIF-2), formation of the ternary complex eIF-2-GTP-Met-tRNAi, which precedes the assembly of a 40S initiation complex, requires the presence of eIF-2 stimulating protein (ESP) and (ii) the interaction of eIF-2 with ESP i... | 287,053 | [
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0.32254,
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0.2365399,
0.04190129... |
Cell-free translation of the mRNAs for the heavy and light chains of HLA-A and HLA-B antigens. | Cell-free translation of poly(A)-containing RNA from the JY lymphoblastoid cell line followed by immunoprecipitation has indicated the presence of mRNAs for both the heavy and light chains of HLA-A and HLA-B antigens in these preparations. Both chains are synthesized with an NH2-terminal extension, approximately 20 res... | 287,067 | [
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0.8568882,
0.06087846,
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... |
Pregnant mice are not primed but can be primed to fetal alloantigens. | In this report we present evidence gathered from various stages of murine pregnancy that indicates that pregnant females have no demonstrable immune effector function directed against their semiallogeneic fetuses. Specifically, by using in vitro assays we found that cytotoxic lymphocytes were not present in pregnant mi... | 287,081 | [
-0.1409986,
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0.09386615,
0.0340352,
... |
Chronic granulocytic leukemia: long-term remission in a patient with familial sarcoidosis. | A patient is described who has chronic granulocytic leukemia (CGL) and familial sarcoidosis, and who has been in complete remission for six years after a single course of busulfan therapy. Her bone marrow Philadelphia chromosome persists and the leukocyte alkaline phosphatase activity remains subnormal. Leukocyte alkal... | 287,201 | [
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0.3244573,
0.05998303,
0.0362798,
-0.0469662,
0.07548548... |
[Otorhinologic and endoscopic findings in cleft palate patients with special reference to velopharyngoplasty]. | Our findings (190 patients of whom 45 underwent follow-up examination) permit the conclusion that the velopharyngoplasty according to the principle of Sanvenero-Roselli, as modified by Heiner, does not lead to an increase in tympanic findings (preoperatively, 73%; postoperatively, 71%). The evaluation of the results fr... | 287,267 | [
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0.04719608,
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Aspects on ripening of the cervix and induction of labor by intracervical application of PGE2 in viscous gel. | In this survey the effect of intracervically applied prostaglandin E2 (PGE2) on the pregnant uterus is outlined. It is concluded that PGE2 decreases cervical resistance and stimulates the myometrium to contract. In small doses (0.25 mg and 0.5 mg) PGE2 produces a rapid and prominent ripening of the cervix without syste... | 287,314 | [
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0.2986908,
0.311526,
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... |
The noise protection effect of the stapedius reflex. | The purpose was to estimate the attenuation and protection effect of the acoustic stapedius reflex on the inner ear. The acoustic stapedius reflex was recorded by means of extratympanic manometry (ETM). This method was used, as it is able to differ between the stapedius and the tensor reflex. Patients with unilateral B... | 287,319 | [
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0.1054624,
0.2022284,
... |
Impedance screening for middle ear disease. | Pure tone audiometry has hitherto been employed as the sole means of indentifying ear pathology. During the last decade it has been demonstrated that even hearing which is normal according to pure tone sweep check screening audiometry (20 dB) can be associated with middle ear pathology. With the intention of identifyin... | 287,339 | [
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0.3943909,
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0.300651... |
Mesiodistal crown diameters of permanent teeth in male American Negroes. | The mesiodistal crown diameters were measured in a group of fifty-six male American Negroes from the recruit population at the Great Lakes Naval Training Center and compared with previously reported data on Caucasians from the same population. The results indicate that tooth size is consistently larger in the Negro sam... | 287,387 | [
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Loaiasis (Loa loa) in an African student in Indiana. | Loaiasis was seen in an African student in Indiana, who had non-specific complaints, leukocyte count of 8,400/mm3, a 47% eosinophilia, and a high Loa loa microfilaremia. Successful treatment with diethylcarbamazine (Hetrazan) produced no allergic manifestations and no reactions to the adult parasites were evident. | 287,388 | [
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0.09469611,
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0... |
Human health effects from accidental release of tetrachlorodibenzo-p-dioxin (TCDD) at Seveso, Italy. | This paper is a progress report of the epidemiologic work carried out under the supervision of the Lombardy Regional Authority during the two years elapsed from the accident in a TCP-producing factory (ICMESA) in Meda (Italy), which resulted in the contamination of several towns of a large, densely populated area calle... | 287,395 | [
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0.5625573,
0.05547706,
0.4830782,
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... |
[Pathomorphology of the lymph nodes and the genesis of myeloid infiltrates in them in acute granulocyte-type leukemia]. | Five hundred lymph nodes taken from various parts of the body in 89 patients who had died of acute granulocytic leukemia at the age of 3 to 71 years were examined. The degree of involvement of lymph nodes of the same patient was different and depended of their site: more frequent and pronounced changes were found in su... | 287,418 | [
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0... |
Progressive polyradiculoneuropathy: treatment with Azathioprine. | A case is presented of a 64-year-old male with chronic inflammatory polyradiculoneuropathy (CIP) relentlessly progressing (despite steroids) to virtually complete quadriplegia over seven months. Once commenced on Azathioprine he dramatically improved over a six week period. The truly progressive form of CIP is rare. It... | 287,463 | [
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0.2480485,
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0.1450985,
0.07035234,
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0.1702004,
... |
Juvenile Reiter's syndrome. | A case of Reiter's syndrome occurring in an 11-year-old, pre-pubertal boy is described. The boy was a heterozygote for the histocompatibility antigen B27 and other arthritic members of his family included his mother with colitic arthritis and an aunt with ankylosing spondylitis. His HLA-B27 negative sibs have remained ... | 287,465 | [
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0.2343988,
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Eosinophilia, chloromas and a chromosome abnormality in a patient with a myeloproliferative syndrome. | The existence of eosinophilic leukemia remains controversial since many authors challenge the existence of this entity. We present a patient with a hypereosinophilic syndrome whose findings were consistent with a leukemic process. The patient's course was marked my signs and symptoms of myeloblastoma formation and his ... | 287,548 | [
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0.09072287,
0.02608347,
-0.068... |
Prolongation of survival time of mice inoculated with myeloid leukemia cells by inducers of normal differentiation. | Studies were made on the effects of inducers on the leukemogenicity of sensitive mouse myeloid leukemia cells (M1) that could be induced to undergo cell differentiation into mature granulocytes and macrophages in vitro by incubation with inducers (certain proteins, bacterial lipopolysaccharides, or glucocorticoids) and... | 287,553 | [
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0.3727583,
0.4160318,
0.0786963,
-0.059202... |
Biochemical parameters of growth inhibition of human leukemia cells by antitumor anthracycline agents. | Ten antitumor anthracycline derivatives used in this study inhibit growth of a human leukemia cell line over a range of potencies exceeding four orders of magnitude. The agents vary from each other at C-4 and C-13, with stereochemical differences at C-4' and substitutions at C-14 and N. Drug retention, DNA damage, and ... | 287,555 | [
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... |
Clinical studies with rubidazone. | One hundred and thirty-three patients, 94 with acute luekemia and 39 with solid tumors, received rubidazone, alone or in combination, at M. D. Anderson Hospital. The initial study, a phase I--II study carried out in 39 patients with acute leukemia, revealed substantial antileukemic activity with optimal results at a do... | 287,557 | [
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The craniofacial complex in cleft lip and palate: an update review of anatomy and function. | This report has been prepared for the purpose of updating the previous State-of-the-Art reports on the status of research on the anatomy and physiology of cleft lip and palate (Dickson, et al,. 1974, 1975; Maude-Dickson, 1977). It covers the literature from August, 1976 to August, 1978, on middle ear musculature, the a... | 287,579 | [
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0.01255583,
-0.3776304... |
A two-wave interview study of frequency of dental visits and dental complaints. | A panel of 268 persons were interviewed twice at an interval of 2 years concerning their visits to dentists and their dental status. The answers they gave on the two occasions agreed well, except for the year of the last visit if it had taken place long ago. This was true both for the people who had gone to the dentist... | 287,581 | [
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0.337802,
0.2186782,
-0.00308... |
Self-regulation in the dental profession. | Structured and open-ended questions were posed in a survey of dentists in solo and nonsolo practices to test assumptions concerning clinical norms and the self-regulatory aspect of the health professions. The importance of autonomy in their perceptions of practice influenced the dentists' responses to several developme... | 287,710 | [
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0.04356173,
-0.08415265,... |
Transpositional flap technique for mandibular vestibuloplasty. | Various surgical techniques for a mandibular vestibuloplasty have been advocated. A transpositional labial flap technique used by us for 23 patients since May 1976, and based on a procedure described by Edlan, has been presented with results of nine-month follow-up examinations of six patients. Clinical, radiographic, ... | 287,712 | [
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0.1608775,
... |
Change in the gonial angle. | Cross-sectional studies have promoted the view that the gonial angle is increased by age and by the edentulous state. Longitudinal studies do not support this view. It is proposed that the data support the concept that the gonial angle may show enlargement or reduction, as may be expected of any bony angular relationsh... | 287,769 | [
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0.0205295... |
Color stability of temporary restorative materials. | In this study it was shown that: 1. There was a statistically significant initial color difference in materials labeled shade 65. 2. Rough materials darkened significantly more than polished materials. 3. There was not statistically significant over all difference in the amount of staining between air-cured and pressur... | 287,790 | [
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... |
Antecedents of dental fear. | Early dental experiences were described in essay form by 225 college students reporting either "high" or "low" fear of dentistry. Antecedent factors which appeared to differentiate the two groups most clearly included pain experiences and dentist behaviors. Results were interpreted as supportive of a social-learning mo... | 287,803 | [
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Mitogen-induced changes in the fluorescence polarization of fluorescein in normal human lymphocytes: a membrane event? | The fluorescence polarization of human lymphocytes undergoing fluorescein fluorochromasia was measured in a system in which antifluorescein IgG was used to quench the extracellular emission of fluorescein leaked from the cells. The polarization values obtained from control cells were similar to those obtained by other ... | 287,826 | [
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... |
Transmission electron microscopy of fetal rat brain cells during neoplastic transformation in cell culture. | Fetal rat brain cells were investigated by transmission electron microscopy during neoplastic transformation in long-term cell culture. Before transfer of the cells to culture, BD IX rat fetuses were treated with a single transplacental pulse of N-ethyl-N-nitrosourea (75 micrograms/g body wt) on the 18th day of gestati... | 287,834 | [
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0.4864341,
0.01692585,... |
Geographic distribution of peptic ulcer disease in Western Samoa. | A survey of peptic ulcer disease in Western Samoa is described. As compared with New Zealand experience, an unusually high prevalence of peptic ulceration is documented. A remarkable and significant variation in the geographic distribution of cases is reported. Regions of high prevalence were significantly associated w... | 287,948 | [
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0.2368278,
0.3387618,
-0.08804519,
0.1647302,
0.3871058,
-0.1318848,
... |
The passive hamstring stretch test: a comparison of clinical estimates with tension gauge measurements. | A comparison of the clinical estimate of the available passive stretch in the hamstring muscles is made against the changing tension in a spring gauge, as the leg is raised. It was found that the angle at which rotation was palpable in the contralateral anterior superior spine occurred after there was a sharp rise in t... | 287,950 | [
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... |
Cold agglutinin disease. Report of a case. | Cold agglutinin disease is an autoimmune hemolytic anemia with varying causes. Two major types are recognized, with different clinical manifestations. Cold agglutinins are circulating antibodies capable of erythrocyte agglutination. However, the reaction is readily reversible. Treatment of the disease is variable. A ca... | 287,986 | [
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0... |
Delimitation of a promoter for RNA polymerase III by means of a functional test. | A Xenopus laevis DNA segment containing the structural gene for tRNA1Met and 22 base pairs at the 5' side of the gene is active in tRNA production. The DNA segment was ligated to sea urchin histone DNA and was also inserted into plasmid pCR1. Both recombinant DNAs were shown to produce mature tRNA1Met at a high rate wh... | 288,049 | [
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... |
De novo biosynthesis of an enzymatically active precursor form of bovine pancreatic RNase. | The de novo biosynthesis of RNase (ribonucleate 3'-pyrimidino-oligonucleotidohydrolase, EC 3.1.4.22) was studied in a cell-free rabbit reticulocyte translation system using a polyadenylylated fraction of mRNA isolated from bovine pancreas. Analysis of the [35S]methionine-labeled translation products of pancreas mRNA by... | 288,056 | [
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Initial glycosylation of proteins with acetylgalactosaminylserine linkages. | Epithelial glycoprotein like that produced by the gastric surface consists of a polypeptide chain rich in serine and threonine; to these amino acid residues oligosaccharide chains of variable length are linked. The linking sugar is acetylgalactosamine. To find out whether the initial glycosylation takes place at the ri... | 288,057 | [
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... |
Arachidonic acid is responsible for the smooth muscle-contracting activity of G-acid. | G-acid, a smooth-muscle-contracting substance isolated from human blood plasma, was previously identified as 3-octadecenoic acid. Synthetic cis- and trans-3-octadecenoic acid, however, are biologically inactive. G-acid actually consists of a mixture of fatty acids, characteristic of animal tissues. The biological activ... | 288,059 | [
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0.0333... |
Modulation of binding and bioactivity of insulin by anti-insulin antibody: relation to possible role of receptor self-aggregation in hormone action. | Incubation of physiological concentrations of 125I-labeled insulin with liver membranes in the presence of anti-insulin IgG results in a 7- to 15-fold increase in the specific binding of the hormone. The low-affinity/high-capacity binding sites are replaced by an apparently homogeneous class of high-affinity sites, and... | 288,060 | [
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Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester. | When suspension cultures of human promyelocytic leukemia cells (line HL60) were treated with 12-O-tetradecanoylphorbol 13-acetate (TPA; 1.6-160 nM), more than 80% of the cells adhered to the plastic substrate within 24 hr. Within the same time period the immature azurophilic granulations typical of HL60 promyelocytic c... | 288,066 | [
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0.0681... |
Cell surface antigens of human melanoma identified by monoclonal antibody. | Mouse NS-1 myeloma cells were fused with spleen cells from mice that had been immunized with cells from a human melanoma, M1804. Hybrid cells were grown in selective medium and tested for production of antibody to surface antigens of M1804 cells. Three hybrids that produced antibodies that bound to the melanoma cells b... | 288,077 | [
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Iontophoresis of Li+ antagonizes noradrenergic synaptic inhibition of rat cerebellar Purkinje cells. | Li salts provide effective therapy for manic-depressive psychosis, but the site and mechanism of this effect are not known. We have tested the ability of Li, applied by microiontophoresis, to modify the responsiveness of rat cerebellar Purkinje neurons to iontophoretic applications of norepinephrine and gamma-aminobuty... | 288,083 | [
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[Maxillofacial radiation-induced cancers (author's transl)]. | Radiation-induced cancers are fortunately a very rare complication of radiotherapy for cancers. Sagerman, however, reported 21 cases in a series of 243 patients with retinoblastomas, examined after a period of at least 5 years, and 6 cases were observed in a similar series of 112 children seen at the Curie Institute. T... | 288,162 | [
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0.4481779,
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... |
Bronchial carcinoma. IV. A methodological evaluation of the vitagram index for measurement of quality of survival. | The validity of the Carlens Vitagram Index was tested by using the result of therapy in 48 patients with bronchial carcinoma in advanced disease, 54 patients with localized disease and 34 deceased treated surgically. The Carlens Vitagram Index, which is additional and composed of six items, was correlated to a set of a... | 288,169 | [
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0.0391... |
Bronchial carcinoma. I. A prospective five year study on an unselected carcinoma population in a Swedish county. | No prospective clinical investigations of unselected total materials of bronchial carcinoma have been reported. The clinical profile of 273 patients with histologically verified bronchial carcinoma from a Swedish county during 1971-1976 is presented. The difficulties in making valid comparisons with other literature re... | 288,172 | [
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Serologic analysis of human tumor antigens. II. Reactivity of sera from eleven osetogenic sarcoma patients against autologous and allogeneic tumor cells. | Sera from eleven patients bearing osteogenic sarcomas were tested for reactivity against autologous and allogeneic normal and tumor cells using a sensitive microcytotoxicity assay. Following absorption with human fetal tissue cultured lines, sera from all 11 patients lost reactivity to autologous and allogeneic normal ... | 288,177 | [
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0.1235855,
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Lysozyme activity in saliva from children with various degree of gingivitis. | The lysozyme activity was determined in paraffin stimulated whole saliva from 51 randomly selected children. The average age was 6.5 years. The children were divided into four groups according to their degree of gingival inflammation. An agardiffusion method was used with Micrococcus lysodeikticus as indicator of the l... | 288,181 | [
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... |
[Myoarthropathies: findings and therapy]. | Im myoarthropathies the interplay of the functions of articulation, mandibular joints, muscles and periodontium is disturbed. They are due to occlusal disorders. The oral examination is carried out according to Krogh-Poulsen. The therapeutic procedure involves three steps. Step 1 : elimination of gross occlusal disorde... | 288,226 | [
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[Headache due to functional disorders of the masticatory organ. Headache due to tension of the masticatory muscles]. | Headache in the temporal, frontal and suboccipital regions are described as to case history, findings and differential diagnosis. With due respect to possible further symptoms of dysfunction, the author indicates as principles to treatment: 1. restoration of the continuity of the rows of teeth, and of the occlusal rela... | 288,229 | [
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0.03170809,
... |
[Prosthetic diagnosis within the framework of morbidity analyses]. | In the framework of a morbidity analysis, the author determined in 500 subjects from the working population the frequency distribution of the various types of incomplete dentition and the proportion of actual prosthetic treatment. From this some suggestions were deduced for prosthetic treatment which should be consider... | 288,232 | [
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... |
Hematological side effects from antihypertensive drugs. | To sum up, some hematological side effects are seen after antihypertensive drugs. They are, however, few, usually not severe and furthermore reversible. And so, from the viewpoint of the hematologist, there are no contraindications against antihypertensive treatment. The prevalence of side effects on blood and blood-fo... | 288,302 | [
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Pyoderma gangrenosum and myeloproliferative disorders. Report of a case and review of the literature. | The exact mechanism involved in the pathogenesis of pyoderma gangrenosum (PG) still remains unclear, yet there is an increasing number of reports associating PG with immunologic abnormalities. A correlation between PG and myeloproliferative disorders has also been described. We describe a patient with chronic myelocyti... | 288,320 | [
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0.05300588,
0.03605254,... |
Accentuation of white phosphorus induced fatty liver by phenobarbitone in male rats compared to female rats. | The possible influence of a potent enzyme inducer, phenobarbitone, on white phosphorus fatty liver, was studied. Pretreatment by phenobarbitone for four days in white phosphorus poisoned rats provoked a decrease in mortality and an increase in hepatic triglycerides (fatty liver) in male rats. The activity of uridine di... | 288,340 | [
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0.384293,
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Effects of subacute toluene inhalation on its metabolism and disposition in rat. | Exposure of adult male rats to 300 ppm of toluene for 1 to 15 weeks 6 h daily caused accumulation of the solvent in brain and in perirenal fat. The body solvent content tended to decrease during extended exposure which might be explained by the enhanced activity of drug-metabolizing enzymes in liver. Our findings also ... | 288,342 | [
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... |
Polycystic changes in rat kidney induced by biphenyl fed in different diets. | Groups of rats were fed biphenyl at various dose levels in a semisynthetic diet and in a commercial chow. The effect levels for induction of polycystic kidney lesions were established by means of urinalysis, organ weight changes, light and electron microscopy, and enzyme histochemistry. The no-effect level, was less th... | 288,367 | [
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Osteomalacia due to unusual causes presenting in adults. | Severe osteomalacia due to causes other than malabsorption and, where renal function was impaired, disproportionate to the degree of renal failure, is described in 15 adults. Only one was younger than 46 years, the median age being 59 years. The diagnosis was not made for months in most patients. After investigation, t... | 288,391 | [
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0.1981022,
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The technique of advancement flap haemorrhoidectomy. | Surgery is still the mainstay of treatment for large, prolapsing haemorrhoids. The teaching of Sir Alan Parks, and more recently the work of W.H.F. Thompson, have shown that degeneration of the supportive tissue of the anal canal and the subsequent sliding of the anal lining, was the greatest contributing factor in the... | 288,414 | [
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0.2279901,
0.3210384,
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Bleeding stomal ulceration. | In a prospective study of patients with haematemesis and melaena, there were 22 admissions of patients with bleeding stomal ulceration, representing 2.5% of total admissions to the Unit. In 16 patients the bleeding was from superficial stomal lesions. These lesions, endoscopically and histologically, resembled alkaline... | 288,421 | [
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0.5446071,
0.0619288,
-0.065271... |
Portal hypertension due to arteriovenous fistula of the gastroduodenal artery. | The record is presented of a patient with severe recurrent bleeding due to portal hypertension. Surgical control of the feeding vessels of a fistulous communication between the gastroduodenal artery and its companion vein arrested the haemorrhage and controlled the portal hypertension. | 288,437 | [
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The need for epidemiological research in road trauma. | This paper discusses the application of epidemiological methods to the public health problem of road trauma. The complex nature of the system is stressed, and some consequent difficulties in the formulation of appropriate hypotheses are outlined. Examples are given. To solve these problems, the paper proposes the forma... | 288,445 | [
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0.1150142,
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0.1803878,
0.2830027,
0.1492995,
-0.0736527... |
Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia. | In a prelminary communication, we described the establishment of a continuous human myeloid cell line (HL-60). Here we report the detailed properties of this cell line and document its derivation from the peripheral blood leukocytes of a patient with acute promyelocytic leukemia. As characterized by light and electron ... | 288,488 | [
-0.1584188,
0.2007901,
0.01558527,
-0.06771498,
0.1994388,
-0.096283,
-0.2668116,
0.1346516,
0.06372894,
0.1118389,
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0.1320117,
0.1018042,
0.08987111,
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-0.3066103,
-0.2643351,
-0.2896598,
0.05808092,
0.2869357,
-0.05225424,
-0.04292214,
... |
[Uses of the occlusal registration instrument (ORI)]. | By means of the occlusal recording instrument (ORI), jaw models can be measured three-dimensionally and filed with respect to axes and skull. In clinical trials evaluated with the ORI, it was shown that the position of the maxilla in the skull can be transferred to the articulator with great accuracy. Suggestions are g... | 288,562 | [
-0.0487833,
0.2713805,
0.197281,
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0.02952748,
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-0.1377196,
0.2015368,
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0.1464152,
0.2652144,
-0.1571437,
-0.1891464... |
[Hypocycloidal tomography of the temporomandibular joint region]. | Tomography has become an important diagnostic method today. Clinically it is necessary to recognize the interpretative problems with tomographs. The reason for and the development of a few frequent tomographic phenomena were described using the results of comparative anatomic and roentgenographic examinations. | 288,565 | [
-0.08670084,
0.0865742,
0.1768382,
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0.3934136,
0.02423891,
0.1686055,
0.3618645,
-0.04456996,
-0.006952843... |
[Patient motivation for oral hygiene from the dentist's viewpoint]. | Inhibiting factors to patient motivation for oral hygiene are found both with the patient and the dentist. These factors were considered in terms of the daily practice. The concept of oral hygiene motivation, described used primarily with children was. | 288,568 | [
-0.1658928,
0.1482523,
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0.1578555,
0.3345853,
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0.1132411,
0.2506154,
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0.03541138,
... |
[Methods for the partial preservation of teeth (hemisection etc.)]. | The term hemisection, root amputation and tooth separation are defined. These methods of treatment should be employed after other proven therapeutic measures have failed and there is justification in the total situation for partial tooth preservation. Correct root canal filling of the remaining dental stumps is essenti... | 288,570 | [
-0.00336824,
0.236269,
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0.0410656,
0.05261772,
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0.1921354,
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0.03132983,
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-0.03557339,
0.1380821,
-0.4177768,
-0.003102195,
0.3228014,
0.1940935,
0.2252922... |
Decrease in insulin receptors during Friend erythroleukemia cell differentiation. | The Friend erythroleukemia cell has an insulin receptor with all the properties of mammalian insulin receptors: rapid, reversible, and saturable binding of insulin; specific for insulin and insulin analogs; inversely proportional to temperatures; sharply pH dependent (optimum = 8.0); and demonstrated ligand-induced acc... | 288,716 | [
-0.1256723,
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0.259887,
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0.2380138,
0.1234244,
0.3241773,
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0.08350607,
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0.1282781,
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0.2870965,
0.3166287,
-0.03699221,
0.1639871... |
Tourette's syndrome symptom onset at age thirty-five. | It is apparent to the authors that the primary factors influencing this particular case of Tourette's Syndrome are psychological. The condition appeared to result from threatening environmental conditions causing repression. The repressed material manifested itself in multiple tics, echolalia and coprolalia. Because of... | 288,726 | [
0.1857785,
0.3078932,
0.06891955,
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0.042505,
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0.2320903,
0.469198,
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0.02117077,
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0.1121632,
0.03985512,
-0.2221133,
0.20437,
0.2890068,
-0.01122921,
-0.2597606,
0.014214... |
Storage stability of dental composites. | Composites made from powder-liquid constituents and subjected to elevated temperatures during storage are more stable than those employing pastes. The decomposition of the benzoyl peroxide ingredient is mainly responsible for the increased setting time and the decreased mechanical properties of the resulting composite. | 288,756 | [
-0.1542771,
0.403084,
0.1727478,
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0.1641441,
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0.1834568,
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0.05410981,
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0.03579935,
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0.317146,
0.5460939,
0.138314,
0.05361756,
0.19... |
Hemangiopericytoma of the oral cavity: report of case and review of the literature. | A case of hemangiopericytoma of the tongue has been described. The literature regarding hemangiopericytoma of the oral cavity has been reviewed; 35 cases have now been reported. There is essentially no difference in clinical behavior, treatment, or recurrence rate reported in the oral cavity and, because of the high re... | 288,888 | [
-0.1731285,
-0.1571258,
-0.2672476,
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0.08108316,
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0.4008031,
0.1402292,
-0.1767099,
-0.1942423,
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-0.2786731,
0.2898769,
0.196557,
-0.193605,
0.2289773,
0.2586482,
-0.08827345,
... |
The papilla rotation flap. | A new technique is described for correction of specific mucogingival defects which is designed to encourage rapid healing of the defect and donor areas. Further, this approach often yields a greater width of attached gingiva than other techniques, and is well tolerated by the patient. | 288,906 | [
-0.3128472,
-0.1803659,
-0.137198,
-0.2859901,
0.02879564,
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0.04097431,
0.09509411,
0.375943,
0.1878708,
0.05621679,
-0.2535156,
-0.09164946,
0.02710845,
-0.3667843,
-0.3321909,
-0.4021155,
-0.1333423,
-0.4030589,
0.018172,
0.1256126,
0.1913413,
-0.001816253,
... |
Periodontosis: a case report with scanning electron microscopic observations. | A tooth and associated periodontal tissues from a patient with the diagnosis of periodontosis was subjected to scanning electron microscopic evaluation after reflection of the soft tissue portion of the lingual defect. The cemental surface of the apical portion of the lesion was found to be populated by markedly simila... | 288,908 | [
-0.06996762,
-0.09985786,
0.07263967,
0.2435689,
-0.08446124,
-0.0984235,
-0.1810225,
-0.006707451,
0.3617916,
0.3102961,
0.02755335,
0.07598761,
-0.1961056,
0.4470396,
-0.2922028,
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-0.459341,
-0.03885555,
-0.09847055,
-0.2274162,
0.1220703,
0.4544773,
0.244310... |
Tumor-associated immunity in bovine ocular squamous cell carcinoma detected by leukocyte adherence inhibition microassay. | A microplate modification of the leukocyte adherence inhibition (LAI) assay was used with blood leukocytes from cattle with ocular squamous cell carcinomas (OSCC); control groups were cattle with ocular or cutaneous lesions (not carcinoma) and healthy normal cattle. For the assay, saline extracts of OSCC and skin from ... | 288,934 | [
-0.06987266,
-0.005294624,
0.007420463,
-0.4810639,
-0.1989522,
-0.2740872,
-0.2801762,
0.3130607,
0.09202182,
-0.03898878,
0.03632986,
0.2034645,
0.2556071,
-0.5387514,
-0.4207705,
0.352529,
-0.5091052,
0.1346967,
0.04019624,
0.3907594,
0.3771347,
0.1486084,
-0.03962864,... |
Extreme leucocytosis and prognosis of newly diagnosed patients with acute non-lymphocytic leukaemia. | A group of 87 consecutive patients with acute non-lymphocytic leukaemia (ANLL) who had been treated with large doses of hydroxyurea (HU) as a preliminary to protocol combination chemotherapy is reviewed. The outcome in patients whose initial leucocyte count was 100x10(9)/L or higher (HC group) is compared with that in ... | 288,967 | [
-0.1157379,
0.1403903,
-0.001949919,
-0.5503215,
0.09528644,
-0.2287737,
-0.09676573,
0.0516475,
-0.3567236,
0.1077295,
-0.2976933,
0.5715313,
0.1958849,
0.3482259,
-0.08469386,
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0.1423855,
0.1572563,
-0.09973698,
0.3329007,
0.1798623,
0.07489397,
-0.02271218,
... |
[Ambulatory therapy with fosfomycin in dentistry and stomatology]. | 1-2 g/day or 3-4 g/day phosphomycin were administered per os to children and adults respectively for an average of 5.2 days in the outpatient treatment of 28 males and 18 females with parodontitis, gingivitis and dysodontiasis of bacterial origin. All patients presented swelling of the soft parts and 34 (74%) had hyper... | 288,976 | [
-0.116488,
0.003540829,
-0.1924824,
0.2977543,
0.05758737,
-0.480123,
-0.2496313,
-0.104501,
-0.0289991,
-0.3192575,
0.2194818,
0.1533087,
-0.04247301,
0.2499365,
-0.3769801,
-0.6896788,
-0.2281156,
0.01095439,
-0.05894687,
0.09766562,
0.2163067,
0.06774108,
-0.1802994,
... |
The Tokelau Islands children's study: atoll and New Zealand comparisons: physical growth. | A comparison is made between the birth weights, weights, heights, skinfold thicknesses, and head circumferences of two groups of Tokelauan children aged under 15 years. One group was living in Tokelau on their three home atolls and the other group was living in New Zealand. The children living in New Zealand were in ge... | 289,015 | [
0.3291841,
0.1190552,
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0.1211141,
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0.03467277,
0.1206852,
0.03773201,
-0.5251361,
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0.4420914,
0.01040859,
-0.03554811,
-0.01641604,
-0.06030072,
-0.331... |
Skin diving fatalities in New Zealand. | A review of skin diving fatalities in New Zealand for the period 1961--1973 revealed 28 deaths of which 21 were scuba divers. Two-thirds of the scuba deaths occurred in water less than 15m deep. Running out of air and lack of essential equipment were frequent contributory factors. The pathological findings are presente... | 289,023 | [
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0.1560376,
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0.07136741,
-0.2057558,
-0.03096602,
0.05318672,
0.07049602,
0.064607,
0.08003435,
0.51927,
-0.1517081,
... |
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