title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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[Effect of the color of visual stimuli on evoked human cortical potentials]. | In subjects with normal colour vision and in those with its acquired defects, evoked potentials (EPs) were recorded in the primary and secondary areas of the visual cortex in response to monochromatic stimuli of equal energy and equal brightness. It is shown statistically that in case of stimuli of equal energy the EPs... | 315,139 | [
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The epidemiology of forcible rape. | Problems of measurement of the incidence of rape are considered, and empirical findings are summarized regarding prevalence, demographic and psychiatric characteristics of offenders, spatial and temporal distribution of offenses, victim-offender relationships, and evidence about recidivism and progression of crimes. Fi... | 315,167 | [
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Late coronary bypass graft flow: quantitative assessment by roentgendensitometry. | Quantitative assessment of the flow in 45 saphenous vein aortocoronary bypass grafts in 30 patients was performed by a roentgendensitometric technique. Detalis of the technique are given. Mean graft flow for all grafts measured in the early postoperative period (two weeks) and again in the late postoperative period (si... | 315,217 | [
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The analgesic activity of imidazopyridine derivatives. | Analgesic and antipyretic activities of 2-(4-(2-imidazo-[1,2-a]pyridylphenyl)propionic acid (Y-9213) were studied with various experimental models. The analgesic activity of Y-9213 was found to be more potent than that of indometacin and morphine in the silver nitrate, Randall-Selitto, and phenylquinone writhing tests.... | 315,230 | [
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Log-linear models in the analysis of disease prevalence data from survival/sacrifice experiments. | This paper considers the problem of analyzing disease prevalence data from survival experiments in which there may also be some serial sacrifice. The assumptions needed for "standard" analyses are reviewed in the context of a general model recently proposed by the authors. This model is then reparametrized in log-linea... | 315,241 | [
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[Effect of thymectomy on induction of immunologic tolerance in the effectors of delayed hypersensitivity]. | The influence of thymectomy (Tx) on induction of tolerance of delayed type hypersensitivity effectors (DHE) was examined. Tx did not interfere with induction of tolerance to sheep red blood cells (SRBC) achieved with combined injections of the massive dose of the antigen and cyclophosphamide (Cy). Tx resulted in prolon... | 315,242 | [
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The binding of ouabain to normal and chronic lymphocytic leukemic lymphocytes. | The binding of the cardiac glycoside, ouabain, to cells had been used to quantify the number of active cation pumps. In this study, lymphocytes were incubated with 3H-ouabain and the equilibrium binding analyzed for the maximal number of specific binding sites. Lymphocytes from normal peripheral blood bound 44,200 +/- ... | 315,246 | [
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The T-lymphocyte as a diploid reference standard for flow cytometry. | T-lymphocytes prepared from the peripheral blood of normal individuals exhibit uniform postmitotic DNA contents that are constant from individual to individual when fixed in ethanol and stained with mithramycin, or when fixed in formalin and stained with acriflavine-Feulgen and analyzed by flow microfluorometry. T-lymp... | 315,268 | [
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Paralytic poliomyelitis in a child with agammaglobulinemia. | This paper gives the clinical, immunological and virological data on a patient with agammaglobulinemia who developed paralytic poliomyelitis. The patient was a 3 year-old boy who had a typical B-cell defect without a T-cell defect. He had profound hypogammaglobulinemia and defective plasma cells and had repeated pyogen... | 315,313 | [
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Pharmacokinetics of fenbufen in man. | The pharmacokinetics of fenbufen (3,4-biphenylcarbonyl proprionic acid) a new antiinflammatory agent, and its metabolites, gamma-hydroxy-4-biphenylbutyric acid and 4-biphenylacetic acid have been studied after oral administration to seven patients with rheumatoid arthritis. Fenbufen was administered as a single oral do... | 315,314 | [
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Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. III. Human diploid fibroblasts. | The induction of inactivation and mutation to thioguanine-resistance in cultured human diploid fibroblasts was studied after exposure to ionising radiations with LET's in the range 20--470 keV micrometer-1. Unique r.b.e. values were obtained for inactivation and mutation induction with nine different qualities of radia... | 315,389 | [
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Correlation of in vitro susceptibility with in vivo efficacy in mice for cefoxitin in comparison with cephalosporins. | Agar minimal inhibitory concentrations and mouse protection test effective doses were determined for each of four beta-lactam antibiotics against each of 12 Gram-negative and 3 Gram-positive bacterial cultures. The beta-lactamase activity of these cultures also was studied. The data were examined to determine whether r... | 315,403 | [
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Characterization of a peptide released during the reaction of human alpha 1-antitrypsin and bovine alpha-chymotrypsin. | The release of a peptide (molecular weight: about 3,600) was observed during complex formation between human alpha 1-antitrypsin (alpha 1-AT) and bovine alpha-chymotrypsin, when monitored by gel-electrophoresis in the presence of sodium lauryl sulfate. Release of the peptide was proportional to the extent of complex fo... | 315,407 | [
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Demonstration in vitro of cytotoxic T cells with apparent specificity toward tumor-specific transplantation antigens on chemically induced tumors. | Chemically induced tumors of mice exhibit apparently unique antigenicity upon syngeneic transplantation into appropriately immunized hosts. An in vitro counterpart of this pattern in terms of specificity has not been reported. Data are presented that demonstrate that immune peritoneal exudates contain cells cytotoxic f... | 315,425 | [
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Subpopulations of human T lymphocytes. XII. In vitro effect of agents modifying intracellular levels of cyclic nucleotides on T cells with receptors for IgM (T mu), IgG (T gamma), or IgA (T alpha). | Purified peripheral blood T lymphocytes were incubated with inducers of cyclic nucleotides and examined for the numbers of T cells with receptors for IgM (T mu), IgG (T gamma), or IgA (T alpha). Isoproterenol and theophylline, agents known to increase cAMP levels at 10(-3) to 10(-6) M concentrations, significantly decr... | 315,428 | [
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Clonal distribution of HLA-restricted antigen-reactive T cells in man. | The [3H]thymidine suicide technique was used to test the hypothesis that the response of immune human T cells from HLA-D/DR heterozygous donors to the soluble protein antigen purified protein derivative (PPD) is clonally expressed and consists of the concurrent proliferation of at least two separable subpopulations of ... | 315,445 | [
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The heat produced by frog muscle in a series of contractions with shortening. | 1. Heat production has been measured in muscles undergoing rapid shortening 1 sec after the start of stimulation in a 2 sec tetanus. In a series of three such tetani where the periods of shortening were separated by 5 sec the shortening heats in the second and third tetani were 111 (+/- 4)% and 116 (+/- 6)% respectivel... | 315,460 | [
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Maturation in B lymphocytic leukaemia. | Surface markers were studied serially in two cases presenting as acute B cell lymphocytic leukaemia. The leukaemic lymphocytes in both cases had the mouse erythrocyte receptor (MER) and surface immunoglobulin (SIg) with lambda light chain. Changes interpreted as an increase in immunological differentiation were observe... | 315,471 | [
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Spinal epidural neurostimulation for treatment of acute and chronic intractable pain: initial and long term results. | Spinal epidural neurostimulation, which evolved from dorsal column stimulation, has been found to be effective in the treatment of acute and chronic intractable pain. Urban and Hashold have shown that it is a safe, simplified alternative to dorsal column stimulation, especially because laminectomy is not required if th... | 315,523 | [
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Implications of Ewald's second law for evaluation of vestibular function. | The significance of Ewald's second law in the evaluation of the vestibulo-ocular reflex (VOR) was investigated using the transfer characteristics of the vestibular and VOR systems in normal rabbits and rabbits in which one horizontal semicircular canal had been blocked. The transfer characteristics of the vestibular sy... | 315,530 | [
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Evidence for a large internal pressure in biological membranes. | We have developed a method (hygroscopic desorption) for measuring the binding of small molecules to membranes. With this method, we have found that the binding of the amphipathic compounds chlorpromazine, 2,4-dinitrophenol, and 1-decanol to various cell membranes is remarkably low, with partition coefficients, Kp, no l... | 315,559 | [
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Localization of spontaneously hyperactive B cells of NZB mice to a specific B cell subset. | NZB mice produce numerous autoantibodies and have a subpopulation of B cells characterized by marked spontaneous hypersecretion of IgM. The latter trait is determined by autosomal genes, in F1 hybrids of NZB and normal strains. We tested the hypothesis that the hypersecreting B cells of NZB mice are contained within a ... | 315,562 | [
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Cardiac arrhythmias in the anesthetized patient. | Continuous monitoring of the electrocardiogram provides an opportunity for the veterinary surgeon to perform the surgical procedure in a safe and controlled manner. Arrhythmias can usually be eliminated by lowering the concentration of anesthetic and administering additional oxygen. Antiarrhythmic drugs are required wh... | 315,646 | [
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[Studies on sensitization after repeated topic application of live attenuated influenza vaccine (Gripovax) (author's transl)]. | A long term study with bivalent live influenza vaccine was carried out in 18 subjects with no previous history of egg protein hypersensitivity. Experimental conditions included a nine-fold vaccination schedule with collection of serum and nasal fluid. The parameters studied were determination of serium and local antibo... | 315,676 | [
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Structural difference between the normal PiM1 and the common PiM2 variant of human alpha 1-antitrypsin. | The common PiM2 variant of human alpha 1-antitrypsin (alpha 1-AT) which can be distinguished from the wild type PiM1 by isoelectric focusing (IEF) in a narrow pH gradient, was purified to homogeneity from plasma of a homozygous PiM2/PiM2 subject. The specific trypsin inhibitory activity and the amino acid and carbohydr... | 315,709 | [
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Bilateral endophthalmitis in acute bacterial endocarditis. | A 53-year-old diabetic woman had ketoacidosis, urinary tract infection, and bilateral endophthalmitis. She subsequently developed a ruptured chorda tendineae of the mitral valve, and a diagnosis of acute bacterial endocarditis was made. No organisms were cultured during life or at autopsy. At autopsy, bilateral nongran... | 315,718 | [
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The effect of exposure to heat on intraocular pressure. | During exposure to heat there is an increase of the intraocular pressure in nonacclimatized persons. This increase is not found after heat acclimatization has been carried out. The increase of the intraocular pressure in the nonacclimatized persons can be attributed to the increase of the body temperature due to insuff... | 315,728 | [
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Pulmonary function in heterozygotes for alpha,-antitrypsin deficiency: a case-control study. | In this paper we present the initial cross-sectional data from a prospective study of lung aging in heterozygotes for alpha 1-antitrypsin deficiency. Using a case-control design, our cases included 37 heterozygotes for alpha 1-antitrypsin deficiency, protease inhibitor phenotypes MZ and MS, selected because they were p... | 315,737 | [
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0.4496884,
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0.1483195,
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0.162527,
0.06989944,
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... |
Vascular complications as a result of intra-aortic balloon pumping. | Intra-aortic balloon conterpulsation (IABP) was used to assist 109 patients with extensive myocardial infarcts, unstable angina, cardiogenic shock, and unstable cardiodynamic states after cardiopulmonary bypass over a six year period. Severe vascular occlusion occurred in three patients (3%) which required an above the... | 315,743 | [
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Ocular tilt reaction with peripheral vestibular lesion. | Following inadvertent destruction of the left vestibular labyrinth during stapedectomy, a patient developed a transient abnormality of posture consisting of leftward ocular counterrolling, leftward had tilting, and a right-over-left skew deviation. This postural pattern, known as the "ocular tilt reaction," is the norm... | 315,752 | [
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Limited effect of trimethoprim-sulfamethoxazole prophylaxis on Pneumocystis carinii. | Trimethoprim-sulfamethoxazole has been proven effective in the treatment and prevention of Pneumocystis carinii pneumonitis in lower animals and humans. How effective the drug combination is in eradicating P. carinii from the host is not known. The immunosuppressed rat model was used to determine whether or not trimeth... | 315,754 | [
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Naloxone reversal of drug-induced diarrhea in mice. | The potential role of endogenous opiates in the mediation of the diarrheal actions of prostaglandin-F2 alpha (PGF2 alpha), 5-hydroxytryptophan (5-HTP) and methacholine was investigated. The interaction of the antidiarrheal agents morphine, propantheline bromide and cyproheptadine on the course of PGF2 alpha-induced dia... | 315,764 | [
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... |
Hereditary multiple exostoses with myelopathy. | A 58-year-old woman with hereditary multiple exostoses had slowly progressive myelopathy due to a vertebral exostosis that compressed the spinal cord at T1-2. She did not show skeletal deformities, but had numerous palpable long-bone exostoses. While CNS complications are rare in hereditary multiple exostosis, 17 other... | 315,766 | [
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[Factors influencing the changes in liver melanin content of amphibia. I. Effect of breeding temperature]. | Frogs caught in winter and kept at summer temperatures, show an increase in the melanic content of the liver. Frogs caught in summer and kept at winter temperatures do not show variations in hepatic melanins with respect to the summer control specimes. This data does not correspond with the natural course of hepatic me... | 315,778 | [
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Identification of lymphoblastic lymphoma cells using a dual assay for T cell differentiation markers. | An assay that simultaneously detects two differentiation markers found in thymocytes is described. There markers include the membrane receptor for sheep erythrocytes (E) and the nuclear enzyme, terminal deoxynucleotidyl transferase (TdT). Cells are incubated with E, pelleted onto slides and then stained for TdT by an i... | 315,815 | [
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Scintigraphic findings of uncommon focal manifestations of Haemophilus influenzae septicemia. | Haemophilus influenzae septicemia is usually associated with a clinical focus of infection. The investigators describe early scintigraphic findings in some uncommon manifestations of H. influenzae septicemia. | 315,856 | [
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... |
Natriuretic and kaliuretic effect of melanocyte-stimulating hormones in hamsters. | The effect of synthetic melanocyte-stimulating hormones (MSH) on urinary excretion of sodiu, potassium and water was studied in hamsters. Synthetic alpha-MSH and synthetic human beta-MSH showed a marked natriuretic and diuretic effect depending on the dosage of hormone. The natriuretic effect of both hormones was appro... | 315,865 | [
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[Intensive care medicine in severe eclampsia (author's transl)]. | The intricacies of the pathophysiology of eclampsia are still unknown. The major symptoms of our 37 year old para 3 are convulsions, hypertension, complete anuria and gastro-intestinal haemmorhage as a result of disseminated ;ntra-vascular coagulation (D.I.C.). The interdisciplinary therapeutic measures are discussed, ... | 315,902 | [
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Human pancreatic amylase polymorphism: formal genetics and population genetics. | The genetically determined polymorphism of human pancreatic amylase (E.C. 3.2.1.1), AMY2, is demonstrated in serum specimens by agarose gel electrophoresis. We investigated 325 mother-child pairs and 2594 unrelated individuals from southwestern Germany. This study confirms the formal hypothesis of two common alleles AM... | 315,910 | [
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One-stage stimulation of human T-lymphocyte colony-forming units (TL-CFU) in a micro agar culture in glass capillaries. | A one-stage micro-culture assay in glass capillary tubes was developed for colony growth of human T lymphocytes. Colony growth by this method did not depend on the addition of growth factors, human serum and erythrocytes. Advantages of this method are its low consumption of materials and the fact that high numbers of c... | 315,924 | [
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A clinical comparison of ampicillin, ampicillin esters (bacampicillin and pivampicillin) and amoxycillin in acute exacerbations of chronic bronchitis. | The results of antibiotic therapy in 271 patients suffering from acute exacerbations of chronic bronchitis are presented. The effectiveness of the better absorbed ampicillin esters (pivampicillin and bacampicillin) is confirmed, but side-effects from the pivampicillin present problems whereas bacampicillin is excellent... | 315,931 | [
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0.089962... |
[Idiopathic scoliosis and equilibrium disturbance (author's transl)]. | The body balance is maintained by the complexed nervous system in the brain stem and the cerebellum. However, the amount of neurological information obtained from this area is relatively small, so that a fine abnormality is easily overlooked or could not be definitely elicited. Examination of the ocular movement become... | 315,979 | [
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Biochemical and biological characterization of lymphocyte regulatory molecules. I. Purification of a class of murine lymphokines. | Murine spleen cells activated by concanavalin A (Con A) in culture produce a class of lymphokine molecules which possess biological activity in a number of lymphocyte response assays. Lymphokines with a mol wt of 30,000, as estimated from gel filtration studies, can be resolved into two components which differ by charg... | 315,987 | [
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Pancreatic elastase and serum alpha 1-antitrypsin levels in beagle dogs smoking high- and low-nicotine cigarettes: possible mechanism of pancreatic cancer in cigarette smokers. | Beagle dogs exposed to cigarette smoke for 600 d experience a significant change in pancreatic elastase levels, as measured in tissue homogenates, compared with their sham-exposed controls. Greater elastase activity was found in the high-nicotine cigarette smokers than in the low-nicotine cigarette smokers. Levels of s... | 316,012 | [
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0.006317879... |
Cigarette smoke inhalation decreases alpha 1-antitrypsin activity in rat lung. | Brief inhalation exposure of rats to three or six puffs of cigarette smoke significantly decreases elastase inhibitory capacity per milligram of alpha 1-antitrypsin in lung lavage fluid. This effect is not observed in ozone-tolerant rats and can be reversed by treating the lung lavage fluid from smoke-exposed rats with... | 316,187 | [
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Cigarette smoking induces functional antiprotease deficiency in the lower respiratory tract of humans. | Current concepts of the pathogenesis of emphysema suggest that it results from an imbalance of elastase and antielastase activity within the alveolar structures. Although emphysema that is associated with hereditary deficiency of serum alpha 1-antitrypsin conforms to this scheme, the major risk factor in the more commo... | 316,188 | [
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Aortoenteric fistula: a mandatory early operative diagnosis. | The records of eight patients with aortoenteric fistulas from 1961 to 1976 were reviewed. The aortoenteric fistulas were primary in three patients and secondary in the remaining five. The most common symptom was gastrointestinal hemmorrhage, seen in seven of eight patients. Four patients also had fever. Seventy percent... | 316,191 | [
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Maximal electrical stimulation for urinary incontinence: report of 98 cases. | Ninety-eight patients with urinary incontinence have been treated with maximal electrical stimulation (MES) The MES method used is a modification of previously used similar methods of maximal stimulation with respect to reduced intensity of stimulation and reduced number of electrodes. Thus, discomfort to the patient d... | 316,213 | [
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[Immunologic properties of malignant and non-malignant L cell sublines. II. Immunogenicity, sensitivity to complement and T-lymphocytes, cell secretions modifying immune reactions]. | The malignant subline of L cells did not differ from the initial benign subline in such immunological parameters as immunogenicity, ability for modigying immunological reactions by their metabolic products, sensitivity to the lyzing action of the complement, ability for surface adsorption of lymphocytes. The cells of t... | 316,241 | [
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Molecular properties of cytochrome P-45011 beta from adrenal cortex mitochondria. | Cytochrome P-45011 beta has been solubilized and partially purified from bovine adrenal cortex mitochondria using chromatography on Octyl-Sepharose CL-4B or DEAE-Sepharose CL-6B. The partially purified P-450 preparations were about 90% pure as judged by SDS-polyacrylamide gel electrophoresis. In the presence of purifie... | 316,244 | [
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Acquired hydrocephalus VI. The influence of some competitive diseases in the treatment of acquired hydrocephalus. | Based on the results of quantitative isotope ventriculography (QIV) a group of 25 patients was divided into 17 hydrocephalic and 8 non- or doubtfully hydrocephalic patients. An atrio-ventricular shunt (A-V shunt) was inserted in all 25 patients. Eight of the hydrocephalic patients improved or became well, while nine hy... | 316,265 | [
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... |
Percutaneous epidural neurostimulation in modulation of paraplegic spasticity. Six case reports. | Six cases of paraplegic, post-traumatic spasticity, alleviated by percutaneous epidural neurostimulation with temporary or permanent implanted neuroelectrodes from the L1 to L4 intervertebral levels are presented. Modulation of this spasticity and secondary beneficial physiological effects were achieved, including regu... | 316,266 | [
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0.1139114,
0.1835711,
0.091628... |
Fever in systemic lupus erythematosus. | The frequency, causes, clinical and laboratory features, and outcome of febrile episodes in 160 hospitalized patients with systemic lupus erythematosus were reviewed. Eighty-three febrile episodes were identified in 63 patients and were ascribed to active lupus erythematosus alone (60 per cent), infections (23 per cent... | 316,284 | [
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0.3019255,
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0.01917201,
-0.38087... |
A visual profile of the alcoholic driver. | Some visual characteristics of the chronic alcoholic were investigated in a sample of 100 male alcoholic patients and 100 matched controls. The purpose of the retrospective study was to determine whether these characteristics may contribute to an increased motor vehicle accident rate among alcoholics. Significant diffe... | 316,286 | [
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0.3690095,
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Vitreous seeds in retinoblastoma, clinical significance and ultrastructure. | Vitreous seeds in retinoblastoma were studied clinically and pathologically. Vitreous seeds were found in 36.6% of retinoblastoma eyes. When tumors involved more than three quadrants of the retina and vitreous seeds were present, the prognosis was poor. When the tumor involved less than one-quarter of the retina, vitre... | 316,288 | [
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0.05554055,
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Infantile glaucoma in unilateral uveal ectropion. | Two case reports are presented where a unilateral uveal ectropion was associated with congenital and late infantile glaucoma. Ipsilateral to the anterior segment anomaly a dysgenetic angle was found to be the basis of the glaucomatous process. The clinical implication that when such an iris malformation is found in a y... | 316,289 | [
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Color blindness linkage to bipolar manic-depressive illness. New evidence. | Linkage between protanopia and deuteranopia and bipolar manic-depressive illness is demonstrated in a sample of eight informative families ascertained in Brussels. Genetic heterogeneity of bipolar affective disorders is also shown in the present study. These results add new evidence to the hypothesis of X-linked domina... | 316,316 | [
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0.2007829,
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[Immunity and neoplasms. Behavior of E rosette-forming lymphocytes in patients with malignant neoplasms]. | The per cent and absolute figures of E rosette forming lymphocytes have been evaluated in the blood of normal subject and of patients with non-neoplastic diseases and with epithelial and lymphoreticular tumours. The percentage of rosetting lymphocytes was not affected by non-neoplastic diseases, whilst it was by tumour... | 316,319 | [
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Ultrastructural development of the vestibular system under conditions of simulated weightlessness. | Electronmicroscopy was used to track the development of the gravity system of frog embryos and larvae which have bred for 5, 7, and 10 d after egg fertilization under conditions of simulated weightlessness on the fast-running horizontal clinostat. Although no differences in the morphologic structure of the organ betwee... | 316,324 | [
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[Electrophoretic separation of rat spleen and thymus leukocytes and their reactions to mitogens in vitro]. | Electrophoretic mobility (EPM) of lymphocytes from the thymus and spleen of August and Wistar rats as well as capacity of lymphocytes with different surface hemagglutinin (PHA) and concanavalin A (Con A) were studied by the method of free flow electrophoresis. Lymphocytes of the rat spleen were shown, depending on the ... | 316,341 | [
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Emergency treatment of variceal haemorrhage. | For the initial control of haemorrhage from oesophageal varices, two methods of vasopressin administration have been compared--the conventional bolus of 20 units and a low dose infusion of 0.4 units per minute. Twenty patients bleeding from oesophageal varices, confirmed by endoscopy, were allocated into either treatme... | 316,346 | [
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Demonstration of surface membrane immunoglobulin on L lymphocytes by the mixed antiglobulin rosetting reaction (MARR) and by the direct antiglobulin rosetting reaction (DARR). | Various preparations of human peripheral blood lymphocytes were examined for the presence of membrane-incorporated immunoglobulin (Ig) molecules using the direct antiglobulin rosetting reaction (DARR) and/or the mixed antiglobulin rosetting reaction (MARR). In an initial study, 97% of lymphocytes depleted of sheep eryt... | 316,413 | [
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[Diseases associated with chronic bronchopathies and plasma alpha-1-antitrypsin deficiency (author's transl)]. | Two groups of patients were selected according to their plasma levels of alpha-1-antitrypsin deficiency from among 58 patients with a chronic bronchopathy. Group I had normal plasma levels of alpha-1-antytrypsin; group II had plasma values lower than normal. The pathologic conditions associated with chronic bronchopath... | 316,492 | [
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The pattern of human lymph node involvement by the non-Hodgkin lymphomas of B-cell lineage. | A total of 93 lymph nodes from 24 patients with a primary malignant non-Hodgkin lymphoma of B-cell lineage was assessed histologically with special reference to the presence or absence of neoplastic B-cells in the lymph node cortex and medulla (B-cell areas) as well as in the paracortical (T-cell area) area, and in the... | 316,500 | [
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0.4330751,
0.2818239,
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0.13... |
Head twitches produced by serotonergic drugs and opiates after lesion of the mesostriatal serotonergic system of the rat. | Electrolytical lesions of the dorsal raphe nucleus in the rat did not change frequency of head twitches produced by codeine and apocodeine. The action of serotonergic drugs was affected differently: the lesion depressed the frequency of head twitch episodes produced by 5-hydroxytryptophan (5-HTP), LSD and quipazine, bu... | 316,525 | [
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Is trisomy cause or consequence of murine T cell leukemia development? Studies on Robertsonian translocation mice. | Trypsin-Giemsa banding studies on T cell leukemias induced in Robertsonian translocation mice by dimethylbenz[a]anthracene and Moloney leukemia virus show a trisomy of chromosome 15 even in cases in which chromosome 15 has undergone centromeric fusion with chromosomes 1, 5, or 6. These results suggest that the duplicat... | 316,545 | [
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... |
Effects of oral administration of D-penicillamine on T- and B-lymphocytes in peripheral blood of rheumatoid patients. | The effects of D-penicillamine on T-lymphocytes (rosette forming cells) and B-lymphocytes (surface IgG- and surface IgM-bearing cells) in peripheral blood of 13 patients with classical or definite rheumatoid arthritis were investigated at 4 weeks, 12 weeks and 24 weeks of treatment. At the same time, the determination ... | 316,588 | [
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alpha-I antitrypsin enzyme deficiency in Indian childhood cirrhosis. | Antitrypsin activity was measured in 50 healthy controls and 100 cases of Indian Childhood Cirrhosis (ICC). The incidence of alpha-I anti-trypsin (Alpha I-AT) enzyme deficiency was strinkingly higher in cases of cirrhosis (39.0%) than in healthy controls (4%). The enzyme deficiency was more prevalent in severe grades o... | 316,592 | [
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Human parotid alpha-amylase secretion as a function of chronic hyperbaric exposure. | Secretion of alpha-amylase by the human parotid gland increased significantly during eight days of hyperbaric exposure. This hyperactivity of the parotid gland presumably resulted from increased autonomic nervous system (ANS) activity attributable to (1)psychological stress in the form of anticipation; (2) dive-related... | 316,598 | [
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Activated silver coatings for surgical implants. | Increase in current from 1.8 to 3 and then to 9 microAH+DC/cm2 controlled respectively 25%, 37%, and 69% of S aureus on intramedullary silver pins (too soft in practice) in femurs of rabbits. Then optimal current of 12 muAH+DC/cm2 was used. On stainless steel pins with intramedullary injection of AgCl or AgNO3, a 25% o... | 316,624 | [
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0... |
Fetoscopy. | A brief report is given on fetal blood sampling by fetoscopy in three fetuses at risk for severe congenital bleeding disorder; hemophilia A in two cases, von Willebrand's disease in one. Published reports on complications of fetoscopy are reviewed. Out of all together about one hundred pregnancies that have been allowe... | 316,637 | [
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0.1934725,
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Sézary cells in ascitic fluid. | Sézary's syndrome is a neoplasm of T-lymphocytes characterized by skin lesions histologically typical of mycosis fungoides together with the presence of malignant (Sézary) cells in the peripheral blood. These cells have a characteristic appearance in tissues, peripheral blood and body fluids, and their presence in larg... | 316,632 | [
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Influence of a mycoplasma respiratory tract infection on sheep erythrocyte and complement receptor-bearing cell composition in the respiratory tract of swine. | Pulmonic and peripheral blood lymphocyte subpopulations in healthy and Mycoplasma suipneumoniae-infected pigs were compared. The T- and the B-lymphocyte populations were counted, the B cells by the complement receptor (zymosan-complement rosettes) technique and the T cells by the ED-rosette technique (sheep RBC-dextran... | 316,662 | [
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Clinical significance of the satellited short arm of human chromosome 17 (17ps +) : a rare heteromorphism? | A 43-year-old impotent male Caucasian had a chromosomal constitution of 46,XY,17ps+. The satellited chromosome 17 was also present in his sister. There is no suggestive evidence that this satellited chromosome causes any clinical abnormality. Based on multiple banding techniques, it is concluded that the 17ps+ is a rar... | 316,666 | [
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Type and contretype signs in monosomy and trisomy 9p. On a case 46,XY, del (9) (pter yields p12:). | A 15-month-old male with a partial monosomy 9p is reported. The comparative analysis with other cases of 9p monosomy demonstrates a typical phenotype which when compared to that of 9p trisomy, permits the delineation of fifteen "type and contretype" signs. | 316,671 | [
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[46,XX/46,XX,del (10) (p13)/47,XX,+r/47,XX,del (10) (p13), + r mosaicism and partial trisomy 10p phenotype (author's transl)]. | The mosaicism 46,XX/46,XX,del(10)(p13)/47,XX, +r/47,XX,del(10)(p13), +r was found in the lymphocytes and the fibroblasts of a patient with the following : profound mental retardation; craniofacial dysmorphism with frontal bossing, fine eyebrows, a large hypoplastic nasal bridge, prognathism of the upper jaw, thick lips... | 316,677 | [
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... |
Role of the von Willebrand factor in atherogenesis. | The von Willebrand factor is a high molecular weight protein which is synthesized by endothelial cells and appears in plasma and platelets. The main function of the factor is in mediating the adherence of platelets to the deendothelialized vessel wall. Animals with congenital deficiency of the factor do not develop the... | 316,693 | [
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[Pediatric metrizamide CT cisternography and CT ventriculography (author's transl)]. | We have studied the diagnostic value of computed tomography with metrizamide CSF enhancement in 37 infants. According to the method of injection, we called CT cisternography, CT ventriculography and CT cystography. These methods were useful for the morphologic and dynamic evaluation of the CSF pathways. We used them es... | 316,706 | [
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Standardization of measures prior to cluster analysis. | A common problem in cluster analysis is the determination of a scale-free measure of distance between individuals. This paper presents a procedure for scaling measurements using a reference individual as a standard of comparison. The procedure is particularly useful in classification of the results of laboratory proced... | 316,712 | [
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Surface glycoproteins from human T, B and chronic lymphatic leukemia lymphocytes isolated by 3 different lectins. | Glycoproteins from the surface of human T. B and leukemic lymphocytes were isolated and partially characterized by using three different lectins, Lens culinaris lectin (Lc), wheat germ agglutinin (WGA) and phytohemagglutinin from Phaseolus vulgaris (PHA). Cells were labelled either with I125 or 3H-fucose and lysed with... | 316,713 | [
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... |
Antibody--antigen complex stimulated lysis of non-sensitized sheep red cells by human lymphocytes. I. Requirements for IgG complexes. | IgG antibody--antigen complexes stimulated lysis of non-sensitized sheep erythrocytes (SRBC) by normal human peripheral blood lymphocytes (PBL). Heat-aggregated human IgG, rabbit IgG-ovalbumin complexes and rabbit IgG-sensitized ox erythrocytes (ORBC) were effective in the induction of SRBC lysis by PBL. However, IgM-s... | 316,751 | [
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Abdominal emergencies. | This brief review of abdominal emergencies is by no means encyclopedic. Indeed, it simply reflects the multiplicity of problems that can occur and suggests the need for a high index of suspicion and an optimistic attitude toward their solution. In addition, the surgeon must keep in mind the fact that cancer patients ma... | 316,758 | [
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-0.143275,
0.114146... |
Subsensitivity of the norepinephrine receptor-coupled adenylate cyclase system in brain: effects of nisoxetine versus fluoxetine. | Chronic administration of the norepinephrine (NE) reuptake inhibitor nisoxetine reduced the sensitivity of the NE receptor-coupled adenylate cyclase system in rat cortex. This subsensitivity, unlike that caused by desipramine (DMI), was not related to a reduction in specific beta-adrenergic receptor binding. The specif... | 316,774 | [
-0.0326216,
-0.140295,
0.04901757,
-0.3263552,
0.1934405,
-0.388485,
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-0.1250085,
-0.01879194,
-0.2305609,
-0.0070123,
-0.01948197,
0.1206947,
0.2225666,
-0.6937458,
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-0.2489016,
0.288471,
-0.311768,
0.1171598,
-0.137429,
0.1163752,
-0.04350838,
-0.... |
Transcriptionally active and inactive regions of nucleolar chromatin in amplified nucleoli of fully grown oocytes of hibernating frogs, Rana pipiens (Amphibia, Anura). A quantitative electron microscopic study. | Chromatin structures contained in nuclei of full-grown oocytes of hibernating northern leopard frogs, Rana pipiens, kept at 4 degrees C were examined by light and electron microscopy, with special emphasis on the morphology of spread nucleoli. Light microscopic inspection of the in situ arrangement revealed that at thi... | 316,784 | [
0.2120728,
0.5846072,
0.01077138,
0.07557778,
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0.08706191,
-0.1428595,
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0.03624328,
-0.09746348,
-0.04401598,
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0.1506575,
-0.4196458,
0.2950298,
0.5129393,
-0.1491617,
0.7354653,
0.2122962,
-0.09848999,... |
Complete elimination of mitosis and DNA synthesis in the lens of the hypophysectomized frog: effects on cell migration and fiber growth. | Three weeks after hypophysectomy mitosis and DNA synthesis are absent in the lens of the leopard frog (Rana iiens). By labeling germinative zone cells in their last DNA synthetic period we were able to follow them in the absence of further proliferation. By this means it has been demonstrated that migration of epitheli... | 316,785 | [
0.08905259,
-0.09506284,
-0.06030119,
0.3476216,
0.0471474,
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-0.2676306,
0.2180721,
0.3009348,
0.007041701,
0.1598247,
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0.149691,
0.01368238,
0.08652267,
0.361849,
0.05714508,
-0.1779006,
... |
Immunobiology of primary neoplasms of the C.N.S. Preliminary results. | A preliminary report on the immunological monitoring of primary intracranial neoplasms is presented. The most important findings concerning B-cells and T-cells mediated immunity and delayed hypersensitivity reactions in this kind of patients, are discussed. Among the fairly significant immunobiological pictures, the Au... | 316,820 | [
-0.2201237,
-0.1005708,
-0.09578229,
-0.1353396,
0.1365542,
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0.06318838,
0.4931642,
0.04277144,
0.1952244,
0.07476369,
0.06341162,
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0.02954362,
0.3359182,
0.05706409,
0.6327732,
0.2790589,
0.2151506,
0.02112165,
... |
Voltage fluctuations at the frog sartorius motor endplate produced by a covalently attached activator. | The depolarization that develops after covalent attachment of trimethylammonium benzoyl to the dithiothreitol-reduced frog sartorius acetylcholine receptor is accompanied by a small increase in voltage fluctuations. The amplitude of the elementary voltage event produced by the covalently attached activator is about 0.0... | 316,828 | [
0.1504635,
0.2208333,
-0.1403133,
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0.1127338,
0.1680253,
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0.1263169,
-0.1288294,
-0.01048854,
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-0.6665155,
0.06069689,
0.3246359,
-0.05731941,
0.2051666,
0.2217942,
-0.01020425... |
Serum proteins--transferrin, ceruloplasmin, albumin, alpha 1-acid glycoprotein, alpha 1-antitrypsin--in rheumatic disorders. | Serum levels of carrier proteins, transferrin, ceruloplasmin and albumin were determined in patients with rheumatic disorders, along with serum levels of acute phase proteins, ceruloplasmin, alpha 1-acid glycoprotein and alpha 1-antitrypsin. Depressed levels of transferrin occurred in rheumatoid arthritis (RA) and syst... | 316,826 | [
0.2643386,
-0.2144523,
-0.3735852,
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0.1950768,
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-0.1124993,
0.0009386752,
-0.2274397,
0.1531398,
0.00540125,
0.2954893,
-0.05906319,
0.1835256,
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0.125038,
-0.04156931,
-0.1080064,
0.2487434,
0.1066048,
-0.3338551,
-0.2691281,
-0.4596488,
... |
IgM anti-IgM cold lymphocytotoxins to B cells. | Cytotoxic antibodies to B lymphocytes have been shown to be IgM. They are not absorbed by red blood cells and therefore not absorbed by red blood cells and therefore not directed against the I antigen of red cells. They are also not inhibited by mannose, as are certain natural cytotoxins against lymphocytes. Methods fo... | 316,939 | [
-0.20293,
-0.1809887,
-0.1938769,
-0.0986281,
0.02313293,
-0.01698225,
-0.2961592,
0.2359536,
0.03818747,
0.2374804,
0.1597262,
0.4006416,
0.2109985,
-0.04545405,
-0.2743062,
-0.1390938,
-0.4030756,
-0.01898789,
-0.02682278,
0.3515348,
0.2910753,
-0.03077009,
-0.1747308,
... |
Epiglottis acuta treated with nasotracheal intubation. | Twenty children, ranging in age from 1--9 years, and one adult suffering from epiglottis acuta were treated with nasotracheal intubation performed under general anaesthesia and with ampicillin. Clinical cure was obtained in all cases with a mean intubation time of 34 hours. The diagnosis, epiglottis acuta, was suspecte... | 316,956 | [
0.1358672,
-0.3271391,
-0.1598341,
-0.2639584,
0.1841364,
-0.2585048,
-0.2547127,
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-0.3011526,
0.1731036,
0.2297173,
0.1244206,
0.01900999,
0.1358235,
-0.2476063,
-0.63758,
0.3908456,
-0.1883788,
-0.190127,
0.3239612,
-0.1675026,
-0.177706,
0.2394... |
Histiocytosis X. V. Serum calcitonin concentrations and osteolytic activity. | Serum calcitonin determinations were carried out in 11 patients with histiocytosis X, 5 having lytic bone lesions. All serum calcitonin concentrations were within normal range. This makes serum calcitonin determinations useless as a marker of osteolytic activity in patients with histiocytosis X. | 316,966 | [
-0.1191852,
-0.2455693,
0.1720634,
-0.3440621,
-0.005143486,
-0.3622535,
-0.3506695,
0.02721108,
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0.07356033,
0.03097771,
0.2680949,
0.1759667,
0.18424,
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-0.1529416,
-0.01358447,
0.1028956,
0.1490531,
-0.08243391,
-0.1820573,... |
Affinity chromatography in the separation of human alpha 1-antitrypsin (alpha 1-AT) and antithrombin-III (AT-III). | The two antiproteases alpha 1-antitrypsin (alpha 1-AT) and antithrombin-III (AT-III) have been purified simultaneously from human plasma. Purification procedure consisted of gel filtration on Sephadex G-200 after initial processing of plasma, followed by ion exchange chromatography on DEAE-Sephadex A50 and DEAE-Cellulo... | 316,999 | [
-0.0393788,
0.3372788,
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0.01106164,
0.1732794,
0.1459323,
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0.1204739,
0.2831373,
-0.01947001,
0.2962444,
0.09241875,
-0.2445208,
-0.5112228,
-0.1018837,
-0.02793132,
0.2281984,
0.3274635,
0.006338884,
0.4291196,
0.1626753,
-0.2825893,
... |
[Morphologic indication for the participation of neutrophil granulocytes in rheumatic cartilage destruction]. | Cartilage destruction in rheumatoid arthritis may be mediated by enzymes of the synovial fluid and by cells of the proliferating pannus tissue. Neutrophilic granulocytes are usually said to affect the cartilage via the synovial fluid, and their local occurrence in the pannus-cartilage border is denied. However, a morp... | 317,005 | [
0.2792741,
-0.002300739,
0.004704738,
0.2811001,
-0.04602715,
-0.3883062,
0.1396953,
0.07812321,
-0.05737158,
0.05424852,
-0.2003764,
-0.196221,
0.09440883,
-0.2499434,
0.08837186,
-0.1594101,
-0.124545,
0.3802038,
0.2230869,
0.4059605,
0.6266745,
-0.1830496,
0.02908729,
... |
Pattern analysis in the study of infantile diarrhoea and other epidemiological problems. | The patterns imposed on records of epidemiological variables by spatial, temporal, and other factors demand a special approach for their identification, characterization, and interpretation. Over the last 10 years, a methodology based on pattern analysis has been developed and put to the test in elucidating selected ep... | 317,018 | [
0.04309227,
-0.2245639,
-0.03365925,
0.04436256,
-0.08243926,
-0.3404195,
-0.2206976,
-0.3830546,
-0.03526835,
-0.2127938,
0.03567088,
-0.1459852,
-0.1259875,
0.06236014,
-0.4682971,
0.1878574,
-0.0777861,
0.2644165,
0.03957963,
0.1056072,
0.1836082,
0.1366321,
-0.1378712... |
An analysis of factors leading to a reduction in iron deficiency in Swedish women. | The prevalence of iron deficiency anaemia among Swedish women of child-bearing age has fallen markedly since the mid-1960s. At that time, population studies in Göteborg and Uppsala showed that iron deficiency anaemia was present in about 25-30% of women. Later, in population studies in Göteborg in 1968-69 and 1974-75, ... | 317,022 | [
-0.1613691,
0.2353706,
0.01514384,
0.2424181,
0.3023034,
-0.1039106,
0.1246091,
-0.1569291,
0.1689954,
-0.1494806,
0.1522883,
0.06855907,
0.06544671,
-0.1836473,
-0.3588705,
-0.09986981,
0.06838091,
0.3278709,
-0.2573086,
0.4465213,
0.3734745,
0.5978487,
-0.299776,
0.15... |
Occupational factors in hypertension in the Nigerian African. | In cross-sectional surveys of arterial blood pressure carried out in rural and urban communities in the Bendel State of Nigeria, mean systolic and diastolic pressure was generally higher in urban than in rural subjects but the differences in particular age groups were statistically significant only in some of them. Two... | 317,086 | [
0.2416273,
-0.04926829,
-0.01683991,
0.2024892,
0.002909708,
-0.2031644,
-0.1009652,
-0.1203461,
0.08656323,
0.2211435,
0.3037628,
-0.03300178,
-0.09325839,
0.02923428,
-0.4480797,
-0.1061346,
-0.335668,
0.09766176,
-0.2808715,
0.2949027,
-0.0662163,
0.359015,
-0.1648816,... |
Carbon-11-labeled amino acids for the rectilinear and positron tomographic imaging of the human pancreas. | Modification of the Bücherer-Strecker amino acid synthesis facilitated the production of DL-[11C]tryptophan and DL-[11C]valine for clinical trials in patients with proven or suspected pancreatic disease. Examples of rectilinear scans and tomographic images of the pancreas are presented in this initial paper. Positron c... | 317,098 | [
0.07748641,
-0.02637612,
-0.3013143,
-0.2354643,
-0.2744848,
-0.2943037,
-0.251147,
0.131681,
0.1777276,
0.2778305,
0.08867255,
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0.1194951,
0.1560905,
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0.1007205,
0.4950789,
0.1524862,
-0.1138571,
0.4549026,
-0.06566317,
-0.... |
Evidence for the failure of IgA specific T helper activity in a patient with immunodeficiency with hyper IgM. | A 28-year-old man with immunodeficiency with hyper IgM was studied. His serum immunoglobulins were characterized by the absence of IgA and low level of IgG associated with high level of IgM. The in vitro pokeweed mitogen (PWM)-induced immunoglobulin synthesis by his peripheral blood lymphocytes was depressed completely... | 317,110 | [
-0.2992494,
-0.2706417,
-0.2468458,
-0.2767932,
0.2086581,
-0.07984929,
-0.03423919,
0.2732458,
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0.141795,
0.1013095,
0.4967602,
0.128848,
0.1754396,
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0.07193751,
-0.05950156,
-0.2122911,
0.1290786,
0.1666927,
0.1699989,
-0.05648739,
0.02... |
[Angiography in posterior fossa extra-axial arachnoid cyst (author's transl)]. | The clinical and roentgenographic findings in two patients with posterior fossa extra-axial cysts are presented, a detailed analysis of the angiographic findings of this congenital retrocerebellar leptomeningeal malformations reported and their differential diagnosis discussed. | 317,143 | [
-0.06863818,
-0.05314641,
-0.1398519,
-0.3074949,
0.09020562,
-0.2879073,
-0.4037351,
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-0.1235948,
0.2492435,
0.07540135,
0.1941071,
-0.08858521,
-0.2999647,
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-0.4965593,
0.3499776,
0.006264457,
-0.1467554,
0.3970815,
0.09257486,
0.037747... |
Composition of human granulocytic colonies as a function of the purification stage of CSF. | Granulopoietic colonies grown in presence of human placental conditioned medium (HPCM), before and after partial purification, were characterized in terms of number of colonies, colony size and cellular composition. Our data demonstrate that the removal of inhibitors present in crude HPCM preparations results in a high... | 317,163 | [
0.1758229,
0.2962853,
-0.1085509,
-0.1392031,
0.1093161,
0.01288172,
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0.001435252,
0.325818,
0.1493981,
-0.2812086,
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0.05450369,
0.1935452,
-0.09814718,
-0.09463381,
-0.01651195,
0.1826938,
-0.1519513,
0.5457781,
0.3260922,
0.1530038,
0.1315486,
0... |
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