title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Principal cell types in the pancreatic islet of a teleost fish, Xiphorphorus helleri H. | By means of correlative light and electron microscopy, five pancreatic islet cell categories are described in the teleost fish, Xiphophorus helleri, each of which has specific light microscopic appearance and fine structure. Different histochemical techniques have been used, including immunofluorescence with antiporcin... | 318,926 | [
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Clinical relevance of polyamines as biochemical markers of tumor kinetics. | The polyamines, spermidine and spermine, and their diamine precursor, putrescine, constitute a unidirectional biosynthetic pathway whose biosynthetic enzymes and accumulation patterns appear to play important roles in the regulation of growth processes. Concentrations of these compounds in physiological fluids are low ... | 318,939 | [
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Genetic localization of the resistance to fosfomycin. | The possible existence of a transferable resistance to fosfomycin was studied in 50 strains of enterobacteria that were isolated in our hospital and which showed a resistance to fosfomycin of more than 256 mug/ml. E. coli K12 E711 was used as a receptor strain in the conjugation -- the times of conjugation were 20 min ... | 318,972 | [
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Bactericidal activity of tinidazole. An in vitro comparison of the effects of tinidazole and metronidazole against Bacteroides fragilis and other Anaerobic bacteria. | The new antiprotozoal agent, tinidazole, was found to be bactericidal against all 52 isolates of obligate anaerobic bacteria tested, 42 Bacteroides fragilis, 4 clostridia and 6 peptostreptococci. The minimum bactericidal concentrations of tinidazole for B. fragilis ranged from 0.25 to 4 mug/ml, and those of metronidazo... | 318,974 | [
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Amoxycillin and co-trimoxazole in acute purulent exacerbations of chronic bronchitis. | 100 hospital patients suffered from acute exacerbations of chronic bronchitis. 50 were treated with amoxycillin in a dose of 500 mg, three times a day for 10 days and the results compared with 50 patients treated with co-trimoxazole in a dose up to 480 mg trimethoprim and 2,400 mg of sulphamethoxazole daily in males, a... | 318,978 | [
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Plasma-dependent chemotaxis of macrophages toward BCG cell walls and the mycobacterial glycolipid P3. | BCG cell walls, associated with oil droplets in the form of emulsions in saline, generate macrophage chemotactic activity from fresh guinea pig plasma. Serum and heat-inactivated plasma were inactive, suggesting involvement of complement or fibrinogen-derived chemotactic factors. Suspensions of cell walls and oil dropl... | 319,056 | [
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Comparison of enteric identification systems. | An evaluation of methods for identification of Enterobacteriaceae was made employing the new commercial Micro-Media Enteric System (MMES) with that of the Analytab Products Incorporated (API) and the Conventional tube media schema as suggested by the Center for Disease Control (CDS). The MMES system employed 20 biochem... | 319,082 | [
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Development of a lysis-filtration blood culture technique. | A lysed-blood culture system that quickly lyses patients' blood near neutrality and is relatively noninjurious to more delicate pathogens such as Haemophilus influenzae and Bacteroides fragilis is reported. The lysing solution includes culture medium, 0.004 M sodium carbonate and bicarbonate, 0.04% Triton X-100,and 0.6... | 319,108 | [
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Aerosolized terbutaline sulfate--an evalution of efficacy and side effects in patients with reversible airway disease. | Aerosolized terbutaline sulfate at a dose of 0.50 mg has been shown to produce significant bronchodilation in patients with reversible airway disease. The purpose of this study was to evaluate the safety and efficacy of 0.50 mg terbutaline aerosol used on a regular dosage schedule over a six-week period. Sixteen ambula... | 319,119 | [
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Harmful effects of near-ultraviolet radiation used for polymerization of a sealant and a composite resin. | An electronic device used to polymerize a sealant and a composite resin has been found to emit 365-nanometer radiation at levels sufficient to kill the bacterium Escherichia coli rapidly (greater than 14,000 ergs per square millimeter per second). Because of the absence of shielding on the probe, significant amounts of... | 319,134 | [
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Bacteriostasis of Escherichia coli by milk. I. Colonization of breast-fed infants by milk resistant organisms. | Human milk has a bacteriostatic effect on Escherichia coli in vitro. The milks of 40 mothers were tested for this effect against E. coli isolated from their stools, from those of their own babies, and from those of babies not breast-fed. The milks had a direct bacteriostatic effect, not dependent on complement, on some... | 319,169 | [
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Escherichia coli serotypes in the faeces of healthy adults over a period of several months. | The faeces of nine subjects eating mainly at home were collected at regular intervals over periods ranging from 2--5 months. Although a large number of serotypes of E. coli were isolated, the variety per subject was lower than is usually found. In most subjects only a limited number of serotypes persisted over most of ... | 319,170 | [
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Increased reproductive fitness of Escherichia coli lambda lysogens. | Lambda lysogens of Escherichia coli reproduce more rapidly than nonlysogens during aerobic growth in glucose-limited chemostats. If the environment is changed to anaerobic growth, the situation is reversed, and the lysogen reproduces more slowly than the nonlysogen. Based on a tetrazolium dye assay, the increased fitne... | 319,255 | [
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The prevention and treatment of sternum separation following open-heart surgery. | A method to prevent and treat sternum separation following open-heart surgery is presented. The procedure consists of passing parasternal continuous sutures placed alternatingly in front and behind the costal cartilages and then including them in the usual parasternal sutures. | 319,304 | [
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Mapping of a gene for a major outer membrane protein of Escherichia coli K12 with the aid of a newly isolated bacteriophage. | A method is described for the enrichment of phages which can adsorb to a specific determinant of bacterial cell surfaces. A phage was isolated which absorbs to E. coli cells containing the "major outer membrane= protein c but not to strains that are lacking this protein. With the aid of this phage a gene, meoA which is... | 319,339 | [
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Joint molecules of lambda DNA as an intermediate of genetic recombination. | Joint molecules of lambda DNA formed in the absence of DNA replication, which may be involved in the process of genetic recombination can be observed as branched DNA derived from different phage particles. These molecules are associated through base-pair hydrogen bonding in synaptic regions, usually with short single-s... | 319,343 | [
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An overview of nursing research in the United States. | In a four-part article, historical perspectives (part I) are reviewed, the development of nursing research in education (part II) is outlined, the contribution of nursing research to practice (part III) is traced, and research resources (part IV) which made the growth possible are described. | 319,430 | [
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Use of muscular, musculocutaneous and omental flaps to reconstruct difficult defects. | These recently popularized flaps make reconstruction of some difficult defects possible in a single operation, with surprisingly good results. They have significant advantage over free flaps (except, perhaps, in the hands ofa few experts) because the chance of failure is considerably less. We do not propose that these ... | 319,466 | [
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[The isolation of enteritis causing Salmonellae from the sputum]. | In the light of the author's diagnostic experience, attention is drawn to the fact that enteritis Salmonellae appear to be more frequently present in sputum than in generally supposed. The diagnostic and epidemiologic implications of this observation are discussed. | 319,522 | [
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[A physician's everyday life in the Engadin around the year 1700]. | Jachiam Elias Frizzun (1657-1714), a barber-surgeon who practised in his native mountain village of Celerina (Grisons, Switzerland) from 1693 to 1713, has left a case-book written in Rhaeto-Romanic and covering the whole period of his professional activity. This unique source shows, among other things, that this villag... | 319,524 | [
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Group B streptococcal endocarditis. | A retrospective study of group B streptococcal endocarditis during 1965-74 in Aberdeen General Hospitals revealed that group B streptococci how principally affect patients in the older age groups with or without a history of antecedent heart disease. Despite recent reports of increased group G infections in obstetric a... | 319,529 | [
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Host presensitization and renal allograft success at a single institution: First transplants. | From June, 1970, to January, 1975, 399 first transplants were performed at the University of Minnesota. Of these 399, 52 had performed antibodies against HLA antigens. When the results of transplantation to these recipients were compared with the results of transplantation to a recipient group matched for age, sex, pre... | 319,548 | [
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Quantitative studies o the activities of anti-human tonsil sera and anti-human spleen sera against B lymphocyte. | Anti-human B lymphocyte serum (AHBS) was obtained by absorbing rabbit anti-human tonsil serum (ATOS) or rabbit anti-human spleen serum (ASPS) with human red cells, liver, neutrophils, thymocytes and glutaraldehyde insolubilized human serum. Specificities of AHBS were checked by the cytotoxicity test, inhibition test of... | 319,566 | [
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Response of the pituitary-testicular axis to luteinizing hormone-releasing hormone in the immature male rat. | Follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone and androstenedione were measured by radioimmunoassays in the sera of immature male rats treated with luteinizing hormone-releasing hormone (LH-RH). A single dose of 10, 20, 40 or 80 ng of LH-RH produced a prompt increase in serum LH: signfiican... | 319,615 | [
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Fundamental study of automatic cyto-screening for uterine cancer. III. New system of automated apparatus (CYBEST) utilizing the pattern recognition method. | An investigation was carried out, both from the point of view of combining features which are considered as being of the highest reliability based on pattern analysis of the nuclear structure and cytoplasm of cells, and the complexity of the apparatus. Several features such as "ambiguity" function were extracted by mat... | 319,612 | [
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Effect of citrus pectin on blood lipids and fecal steroid excretion in man. | Citrus pectin (15 g/day) was added for 3 weeks to metabolically controlled diets in nine subjects. Pectin was consumed with fruit and sugar as a gel in divided doses with meals. Plasma cholesterol concentrations were reduced by a mean of 13% (P less than 0.001). Fecal fat excretion increased by 44% (P less than 0.001);... | 319,647 | [
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Quantitative counterimmunoelectrophoresis for urinary fibrinogen-related antigens. | A quantitative procedure for urinary fibrinogen-related antigens, applying counterimmunoelectrophoresis to serial dilutions of concentrated samples against standards of known fibrinogen concentrations, is described. It is fast, convenient, sensitive enough (r = 0.8729, p less than 0.001), and can be easily incorporated... | 319,649 | [
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Oxolinic acid therapy for urinary tract infections in children. | Thirty hospitalized children with Gram-negative bacillary urinary tract infections were treated with oxolinic acid for 14 to 21 dyas. Fifteen of 17 patients with uncomplicated and 11 of 13 with complicated urinary infections had favorable bacteriologic responses. Resistant organisms developed in four treatment failures... | 319,651 | [
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... |
Routine processing of ophthalmic tissue for light microscopy. | The techniques for processing ophthalmic tissue in our laboratory are described in detail. The procedure for grossing of specimens, and the different time tables for processing are given. We have been able to achieve easily reproducible results using the methods described. | 319,664 | [
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Corneal endothelium under various storage conditions. | Three rabbit corneas each were stored in McCarey-Kaufman (M-K) medium, rabbit serum, and in a moist chamber at 4 degrees C refrigeration for various lengths of observation. The endothelial cells appeared normal under all conditions for the first 24 hours as compared with control corneas processed concurrently with each... | 319,675 | [
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John Dewey: implications for schooling. | Propositions, whether great and lasting or insignificant and passing, reside in the "guts of the living." Each age rediscovers its Plato, Dickens, Newton, or Dewey. Each age rewrites history, redefines science, develops its own theoretical perspectives. Propositions are tentative, conditional, or relative. They depend ... | 319,676 | [
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A comparative study on the dental health status of five precolumbian Peruvian cultures. | In a survey of dental health status of ancient Southern Peru, 101 skeletal remains were studied from five cultures: Paracas, Nazca, Tiahuanaco, Ica, and Inca. The Paracas and Ica cultures exhibited more missing antemortem teeth per mandible than the other cultures. Frequency of missing one or more third molars was less... | 319,680 | [
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The crisis in mental health research. | The author states that the mental health research program of the United States is facing a threat to its survival as a force for public health. He describes the antecedents of this crisis, which include the separation of the National Institute of Mental Health from the National Institutes of Health and other organizati... | 319,690 | [
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Use of transcutaneous electrical stimulation in the control of postoperative pain. | Perception and relief of pain were studied in a varied group of fifty patients who had undergone laparotomy with upper abdominal midline incisions. Twenty-six patients were supplied with functioning transcutaneous electrical stimulators. Twenty-four received nonfunctioning machines. The controls were randomized by a nu... | 319,697 | [
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Improved oxygenation during thoractomy with selective PEEP to the dependent lung. | In 22 patients during thoracotomy in the lateral position, the effects of selective positive end-expiratory pressure (PEEP) to the dependent lung while simultaneously ventilating the non-dependent lung at zero end-expiratory pressure (ZEEP) on (1) inspired O2 concentration required to maintain adequate Pao2 during thor... | 319,703 | [
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Comparison of the effects of continuous negative external chest pressure and positive end-expiratory pressure on cardiac index in dogs. | Continuous negative external chest pressure was used to increase the functional residual capacity in 6 dogs, and the effects were compared with the effects of increasing functional residual capacity using positive end-expiratory pressure. Cardiac index and mixed venous O2 stauration each decreased from control values d... | 319,716 | [
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Bronchial effects of aerosolized delta 9-tetrahydrocannabinol in healthy and asthmatic subjects. | Effects on airway dynamics, heart rate, and the central nervous system of various doses of delta9-tetrahydrocannabinol administered in a random, double blind fashion using a Freon-propelled, metered-dose nebulizer were evaluated in 11 healthy men and 5 asthmatic subjects. Effects of aerosolized delta9-tetrahydrocannabi... | 319,717 | [
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Effects of dimethyl sulfoxide on ocular inflammation. | The anti-inflammatory properties of topical ocular dimethyl sulfoxide (DMSO) were investigated using a standard experimental model of an acute inflammatory ocular inflammation. Ninety percent and 100% DMSO aggravated the inflammatory response, 50% to 70% DMSO had similar responses as the control eye; however, 30% DMSO ... | 319,730 | [
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Clinical evaluation of a hemagglutination method for microsomal and thyroglobulin antibodies in autoimmune thyroid disease. | A simple and reproducible hemagglutination technique for detecting microsomal and thyroglobulin antibodies has been evaluated in normal subjects and in patients with thyroid disease. Microsomal antibodies were detected in 89 percent of all patients with autoimmune thyroid disease and in 97 percent of patients with biop... | 319,737 | [
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Inhibition of multiplication of Mycobacterium leprae by polyinosinic-polycytidylic acid. | Contrary to the results of an earlier study in which polyinosinic-polycytidylic acid [poly(I:C)] administered intraperitoneally to mice had no effect on multiplication of Mycobacterium leprae in the mouse footpad, the local administration of poly(I:C) every 12 h for 15 doses during logarithmic multiplication was found ... | 319,745 | [
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Comparison of microbial counts on beef carcasses by using the moist-swab contact method and secondary tissue removal technique. | When a tissue removal rinse technique was compared to the moist-swab contact method, significantly greater numbers of bacteria were recovered from beef carcasses, especially when the flora exceeded log10 4.5/6.45 cm2. Secondary treatment of the removed surface tissue by blending resulted in a significantly greater numb... | 319,755 | [
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Relapsing E. coli K1 antigen meningitis in a newborn. | A male infant of 32 weeks' gestational age who presented with recurrent apnoea on the second day of life was shown to have an Escherichia coli K1 antigen meningitis. Relapse occurred 6 days after an adequate systemic course of gentamicin and chloramphenicol and intrathecal gentamicin. This was successfully treated with... | 319,766 | [
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Evaluation of doxapram for arousal from general anaesthesia in outpatients. | In a double-blind study of 100 outpatients receiving methohexitone, nitrous oxide and halothane, the administration of doxapram 80 mg i.v. was associated with a significantly more rapid recovery from anaesthesia, the effect being more obvious in women than men. Doxapram produced a reduction of 3-4 min in the time of re... | 319,815 | [
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Preparation of Escherichia coli tRNAs terminating of modified nucleosides by the use of CTP(ATP):tRNA nucleotidyltransferase and polynucleotide phosphorylase. | Two procedures were investigated for the modification of tRNAs at the 3'-terminal nucleoside. The first involved the incubation of an enzymatically abreviated tRNA (tRNA-C-COH) with appropriate nucleoside triphosphates in the presence of CTP(ATP):tRNA nucleotidyltransferase from Escherichia coli and yeast. The E. coli ... | 319,825 | [
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Outer membrane of Salmonella typhimurium. Identification of proteins exposed on cell surface. | Proteins exposed on the outer surface of the outer membrane of Salmonella typhimurium were identified by reacting intact cells with a covalent labeling reagent. Since the outer membrane permitted the free diffusion of small hydrophilic molecules, we used a macromolecular reagent, CNBr-activated dextran, as the non-pene... | 319,828 | [
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Characterization of ribonucleoprotein particles released from isolated nuclei of regenerating rat liver in two different in vitro systems. | The ribonucleoprotein particles released from isolated nuclei of regenerating rat liver in two in vitro systems were studied and the following results were obtained. 1. When the isolated nuclei of regenerating rat liver labeled in vivo with [14C] orotic acid were incubated in medium containing ATP and an energy-regener... | 319,832 | [
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A factor affecting stimulation of aminocylation in plants. | The presence of a factor stimulating the reaction of aminoacylation tRNAs was found in the seeds of lupin, with a molecular weight of 950 as estimated by gel filtration. The influence of this factor on the kinetics of the aminoacylation reactions of lupin, Escherichia coli, Baker's yeast and heterogeneous systems was i... | 319,834 | [
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Effects of glucose and nitrogen source on the levels of proteinases, peptidases, and proteinase inhibitors in yeast. | In Saccharomyces cerevisiae harvested from early exponential growth on glucose-containing media, the specifc activities of proteinases A and B, carboxypeptidase Y, and the inhibitors IA, IB, IC of these three proteinases, respectively, are found to be 10-30% of the specific activities observed in media without glucose,... | 319,838 | [
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Orthotopic liver transplantation: the first 60 patients. | Between May 1968 and 31 December 1976 60 orthotopic liver allografts were transplanted by the Cambridge-King's College Hospital team. During this period there were changes in the selection of patients and their management. Initially some patients were operated on when they were too ill, often because of a prolonged wai... | 319,875 | [
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Brain protein metabolism and the acquisition of new behaviors. II. Immunological studies of the alpha, beta and gamma proteins of goldfish brain. | In a previous study, the labeling pattern of three proteins (alpha, beta and gamma) in goldfish brain was found to change after the animals successfully acquired a new pattern of behavior. In the present study, these proteins were isolated from the brain cytoplasmic fraction, purified by successive gel electrophoresis ... | 319,879 | [
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Hyperbaric oxygen in radiation therapy. | The importance of oxygen with low LET radiations has been established beyond any doubt in many different systems, both plant and animal. While some studies, especially head and neck tumors, are impressive, it has not been demonstrated unequivocally that radiation under hyperbaric conditions is superior to well fraction... | 319,896 | [
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Endometrial cancer: therapeutic decision and the staging process in "early" disease. | An all inclusive, widely accepted system for correlation of indices of pathophysiology in endometrial cancer with a spectrum of therapeutic management has yet to be developed. Improved understanding of tumor growth should lead to more logical, individualized treatment especially in terms of irradiation. To support thes... | 319,900 | [
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Electron dense plaques (calcium binding sites) in the plasma membrane of the endocrine cells in rodent pancreatic islets and parathyroid glands. | Small electron dense plaques (EDP) were found in the plasma membrane of pancreatic islet A-, B- and D-cells and parathyroid chief cells of mice and gerbils. The identification of the EDP was facilitated by the use of special fixation techniques. The EDP may represent sites of calcium binding in the cell membranes. | 319,904 | [
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Clonal growth and maturation to immunoglobulin secretion in vitro of every growth-inducible B lymphocyte. | The frequency of normal murine B lymphocytes initiating growth in diluted suspension cultures in the presence of a B cell mitogen, such as lipopolysaccharide, can be increased approximately 10(4) fold by the addition of 2 X 10(6) normal thymus cells per ml. This increase in the frequency of growing cells by thymus cell... | 319,912 | [
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Absorption of rifampin from various preparations and pharmaceutic forms. | The absorption of 9 rifampin preparations was measured in two seaparate crossover studies on 10 healthy female volunteers. In the first set of experiments, one of the three capsule preparations was absorbed more slowly than the other ones. The absorption of two syrup preparations was nearly twice that of the best capsu... | 319,939 | [
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Stimulated release of hypothalamic growth hormone-releasing activity by morphine and pentobarbital. | Two minutes after the intravenous administration of 1 ml of sheep somatostatin antiserum in the rat, plasma growth hormone (GH) levels had reached a maximal 10-15-fold increase which remained approximately constant up to 90 min. The injection of sodium pentobarbital (2 mg/100 g body wt) led to a rapid and transient ris... | 320,063 | [
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0.009286757,
0.0678834,
-0.1474618,
0.08392869,
-0.3548046,
0.4121108,
0.337918,
0.2244653,
0.4547666,
0.03133303,
0.07084651,
... |
Proteinase mutants of Saccharomyces cerevisiae. | Fifty-nine mutants with reduced ability to cleave the chymotrypsin substrate N-acetyl-DL-phenylalanine beta-naphthyl ester have been isolated in S. cerevisiae. All have reduced levels of one or more of the three well-characterized proteinases in yeast. All have reduced levels of proteinase C (carboxy-peptidase Y). Thes... | 320,092 | [
-0.09853608,
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0.06336772,
0.06723483,
0.3111622,
0.2436859,
0.1188659,
-0.06929811,
0... |
Morphology and physiology of salivary myoepithelial cells. | Myoepithelial cells, which occur in many but not all exocrine glands, are usually quite conspicuous in salivary glands. Their contractile nature seems established beyond doubt, and the morphological similarities to smooth muscle cells are close enough to suggest that they contract by a similar, if not the same, mechani... | 320,128 | [
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0.2783921,
0.05989615,
-0.02290... |
[The present status of vestibular testing (author's transl)]. | Proceeding from the standard aims of every vestibular test, modern fine-quantitative investigatory methods with or without electronystagmographic recording in opposition to the systematic search for spontaneous and provoked nystagmus are presented with a view to their value for medical practice. Examination of spontane... | 320,167 | [
-0.009051895,
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0.3491844,
-0.1763904,
-0.04138071,
-0.01148416,
-0.06557734,
0.054... |
Mutational biosynthesis by idiotrophs of Micromonospora purpurea. I. Conversion of aminocyclitols to new aminoglycoside antibiotics. | By mutation and strain improvement techniques idiotrophs of Micromonospora purpurea, the gentamicin-producing organism, were obtained which require an exogenous source of 2-deoxystreptamine in order to produce gentamicin. Streptamine incorporation afforded a mixture of 2-hydroxygentamicin C as a complex of essentially ... | 320,170 | [
-0.2030384,
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0.06850644,
0.2012835,
0.3179281,
0.3676368,
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0.1153744,
... |
Accumulation of nucleotides by starved Escherichia coli cells as a probe for the involvement of ribonucleases in ribonucleic acid degradation. | The acid-soluble ribonucleic acid degradation products formed by Escherichia coli cells starved for a carbon source have been identified. They comprise oligonucleotides, nucleoside diphosphates, 5'- and 3'-nucleoside monophosphates, nucleosides, and free bases. The majority of these products are excreted phates, nucleo... | 320,188 | [
-0.2754046,
0.01473158,
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0.07923378,
0.03940021,
0.4663966,
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0.1261113,
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0.1450916,
0.1421589,
0.4270549,
0.1708062,
-0.3378484... |
Mode of action of yeast toxins: energy requirement for Saccharomyces cerevisiae killer toxin. | The role of the energy status of the yeast cell in the sensitivity of cultures to two yeast toxins was examined by using 12K release from cells as a measure of toxin action. The Saccharomyces cerevisiae killer toxin bound to sensitive cells in the presence of drugs that interfered with the generation or use of energy, ... | 320,190 | [
-0.1948292,
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-0.04819999,
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0.5062652,
0.358751,
-0.1387188,
... |
Limited proteolysis of nitrate reductase purified from membranes of Escherichia coli. | The heterogeneous form of nitrate reductase released from the membrane fraction of Escherichia coli by heat treatment was converted to a new electrophoretic form by incubation with trypsin. As a result of the trypsin treatment, the heat-released enzyme was converted from an associating-dissociating system to a nonassoc... | 320,211 | [
-0.3782683,
0.2173499,
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0.1183603,
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0.1341679,
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0.1101735,
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0.2141024,
0.2153606,
-0.1494634,
0.3299... |
Gluconeogenesis in cattle: significance and methodology. | Gluconeogenesis is a continual process that is of great importance in ruminants because almost all dietary carbohydrates are fermented to volatile fatty acids in the rumen. In turn, propionate is the only major volatile fatty acid that contributes to gluconeogenesis. Many different techniques and analytical procedures ... | 320,235 | [
-0.1526024,
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0.3006958,
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0.3964866,
0.1904115,
... |
Identification and purification of immunosuppressive activity in the urine of rats and a human patient treated with niridazole. | Administration of the antischistosomal compound niridazole to mice, guinea pigs, and humans results in the suppression of several manifestations of cell-mediated immunity. Sera from animals treated with niridazole blocked the in vitro production of migration inhibitory factor (MIF) while niridazole itself was inactive,... | 320,258 | [
0.002788351,
0.1067477,
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0.1049833,
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0.3296326,
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0.06668665,
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... |
Ontogeny of the antibody-forming cell line in mice. IV. Appearance of cells bearing Fc receptors, complement receptors, and surface immunoglobulin. | The ontogeny of Ig, FcR, and CR-bearing cells in liver and spleen has been followed by using rosetting procedures. These studies demonstrated a sequential appearance of surface receptors during development. Two types of Ig+ cells could be distinguished according to their rosette morphology and adherence to carbonyl iro... | 320,262 | [
0.006725956,
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0.1347312,
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0.2798954,
0.2342983,
0.1173099,
-0.1738968,
... |
Identification of human peripheral T cell antigens. | A new type of differentiation antigens on human T cells was demonstrated by using a heterologous anti-human T cell serum (ATS). This type of antigen, referred to as human peripheral T cell antigen (HPTA), was found on peripheral T cells and medullary thymocytes, but not on cortical thymocytes and B cells. The percentag... | 320,263 | [
0.2829689,
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0.09282478,
0.1753413,
0.1568684,
0.3407784,
-0.1496075,
0.011... |
A radioimmunoassay for human antibody specific for microbial antigens. | A simple and sensitive method for detecting and quantitating antibody specific for microbial antigens is described. Bacterial, fungal, parasitic or viral antigens attached to bromoacetyl cellulose or the intact cells themselves were added to a series of two-fold dilutions of human serum. After a short incubation period... | 320,268 | [
-0.1788597,
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0.2029095,
0.4621286,
0.1723769,
-0.1226538,
-0.0... |
Quantification of in vitro antibody secretion by immune spleen cells. | A simple method to study 19S anti-SRBC antibody production is described. This technique, performed by incubation of immune spleen cells, SRBC and C in the fluid phase, utilises photomeric estimation of antibody mediated haemoglobin release. The test is quicker and more accurate than the two-step haemolytic plaque assay... | 320,270 | [
-0.05157608,
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0.6909015,
0.6235861,
0.1501009,
0.06116437,
-0.... |
Enterotoxigenic Escherichia coli isolated from food. | Approximately 8% of 240 isolates of Escherichia coli obtained from food of animal origin in the United States were found to be enterotoxigenic, as determined in adrenal cells, rabbit ileal loops, and assays in infant mice. These organisms were of diverse serotypes that are not included among the so-called enteropathoge... | 320,279 | [
-0.194951,
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0.005369851,
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0.1972232,
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0.1524149,
0.09352142,
0.04638472,
-0.069... |
The sharpening of scaling instruments: I. An examination of principles. | The theory and practice of sharpening with particular emphasis upon dental scalers and periodontal curettes have been discussed in Part I of this series. Various cutting modes and edge characteristics are described together with the special requirements they present in sharpening. Different approaches to sharpening are... | 320,305 | [
-0.1240058,
0.3214729,
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0.01053793,
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0.5346819,
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-0.2121404,
... |
Acid and pepsin secretion of separated gastric pouches during perfusion of antral pouches with cholinergic stimulating and blocking agents and lignocaine. | 1. Secretion of HCl and pepsin from abomasal fundic pouches was studied in sheep during perfusion of antral pouches with cholinergic blocking and stimulating agents and lignocaine. 2. Resting secretion was reduced to about 50% of control levels and secretory responses to feeding were largely or completely blocked durin... | 320,308 | [
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0.09568578,
0.07379375,
0.04401884,
0.4576408,
0.175467,
-0.142669,... |
Transfer of R factors from Escherichia coli to salmonellas in the rumen of sheep. | Adult sheep were given into the rumen c. 10(8) cells each of donor strains of E. coli containing an R factor and prospective salmonella-recipient organisms and were maintained on a diet of lucerne chaff; the animals excreted the organisms, remained healthy, and no transfer of the R factor was detected. When the animals... | 320,337 | [
0.02390053,
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0.2135672,
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0.001091684,
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0.007098299,
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0.2411748,
0.3170021,
0.2529797,
0.1399585,
-0.04836563,... |
Xanthogranulomatous pyelonephritis in children. | Xanthogranulomatous pyelonephritis in children, contrary to adult onset, rarely is associated with non-function or calcification. The lesion is predominantly on the left side in children. There appears to be a normal humoral but temporarily impaired cellular immune response in addition to sustained depression of polymo... | 320,349 | [
-0.1887607,
0.1443406,
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0.03742275,
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0.2138444,
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0.039775,
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0.1265992,
-0.1441776,
-0.2716035,
... |
[Bone marrow transplantation in a case of acute lymphoblastic leukemia (author's transl)]. | In a 6-year-old girl with acute lymphoblastic leukemia, pericardial effusion and mediastinal mass remission lasted for 7 wks. only in spite of intensive chemotherapy. Bone marrow transplantation for a HL-A-identical, MLC-negative sister was attempted after antipleukemic therapy (Cytosin-arabinoside, BCNU, Cyclophospham... | 320,374 | [
0.0003341178,
0.07551698,
-0.1478271,
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0.1121748,
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0.09924404,
0.1409239,
0.4789889,
0.09464937,
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0.05393464,
0.1989449,
0.6391168,
-0.273632,
-0.3681335... |
The functional capacity of guinea pig megakaryocytes. II. The uptake of particles and macromolecules and the effect of rabbit antiguinea pig platelet antiserum. | The capacity of megakaryocytes to take up particles and macromolecules was tested by exposing them to homologous erythrocytes, latex particles, Micrococcus lysodeikticus, and horseradish peroxidase. Uptake of particles 1.1 to 7 mum. in size was extensive under the experimental conditions employed. After uptake of each ... | 320,386 | [
0.1889029,
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0.1243655,
0.0936131,
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0.2403454,
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0.06776049,
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0.1445223,
0.3476327,
0.2307165,
0.3112679,
0.5139534,
-0.06980137,
-0... |
Trans--pulmonary artery repair of ventricular septal defect associated with congenitally corrected transposition of the great arteries. | This report documents successful trans-pulmonary artery repair of ventricular septal defect (VSD) in 2 patients with congenitally corrected transposition of the great arteries, one patient having associated subpulmonic stenosis. In selected cases, the method of repair that is described offers significant advantages ove... | 320,393 | [
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0.02117529,
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0.285479,
0.2901282,
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0.1200784,
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-0.1271867,
0.03884474,
0.0613725,
-0.09954719,... |
Immunologic aspects of pulpal-periapical diseases. A review. | The relationship of immunologic concepts to endodontic diseases is discussed. Immunologic mechanisms are considered, including antigens, haptens, antibodies, and cell-mediated responses. Studies of immunologic manifestations in endodontic diseases are given. These include (1) localization of plasma proteins in inflamme... | 320,531 | [
-0.328892,
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0.2306869,
0.2661842,
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0.3642938,
0.3207877,
0.1392873,
-0.07541649,
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0.1758692,
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-0.1354002,
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-0.2635982,
-0.189266,
0.2000216,
-0.01158035,
0.08... |
[Reimplantation and autotransplantation of teeth. Review of the literature]. | The most important factor for a favorable long-time prognosis of replanted and autotransplanted teeth is a short extra-alveolar periode. Implanted teeth should be followed radiographically with special attention to external resorptions as these correspond well with the histological picture. Avulsed teeth replanted with... | 320,556 | [
-0.09662766,
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0.1668915,
0.2963141,
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0.1853943,
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0.1184506,
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0.07865405,
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0.07205128,
-0.1826582,
-0.03504287,
0.3793713,
0.5008481,
-0.13558... |
Isolation of ribosomal protein-RNA complexes by nitrocellulose membrane filtration: equilibrium binding studies. | E. coli ribosomal proteins are retained by nitrocellulose filters. In contrast, 16S RNA passes through nitrocellulose filters. We have found that specific protein-RNA complexes involving single proteins also pass through nitrocellulose filters. Thus, by utilizing radioactively labeled r-proteins, nitrocellulose filtrat... | 320,562 | [
-0.03366941,
0.3053506,
0.06168467,
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0.00287894,
-0.05611889,
-0.4534309,
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0.3063892,
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0.1540145,
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0.08764652,
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-0.3323975,
-0.1993556,
0.1123207,
-0.1665409,
0.3428631,
-0.03938148,
-0.020994... |
Experience with the deltopectoral flap. | The deltopectoral flap is a most versatile source of skin coverage or mucosal lining (or both). There is remarkable safety in the use of this flap in relation to its size, and there is only limited need for delay--because it pedicle is an axial flap. Nonetheless, the terminal part requires the attention to detail which... | 320,613 | [
-0.2029961,
-0.155094,
-0.1998585,
-0.2856148,
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-0.3201548,
0.04753546,
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0.1069516,
0.09044647,
0.05221357,
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0.06775319,
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-0.1592138,
0.00499525,
-0.1307965,
0.03878291,
0.3768388,
0.04566872,
-0.044320... |
Enzyme immunoassay of hepatitis associated antigen (HAA). | Due to its high sensitivity, radioimmunoassay has become of great importance in the detection and measurement of levels of proteins and steroids in body fluids. However, this method involves the use of expensive equipment and radioactive material. Herein is described an alternate method to radioimmunoassay, which uses ... | 320,636 | [
0.05978576,
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-0.2218674,
0.2107263,
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0.1164457,
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0.08249009,
0.3248823,
0.1637758,
0.1659648,
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0.3055178,
0.1302217,
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-0.09960742,
-0.2624487,
0.2588435,
-0.3089396,
-0.2963237,
0... |
Preventive practices in schoolchildren in Oppegard, Norway, related to some background factors. | As part of a clinical trial among schoolchildren in a suburban community just outside Oslo, dental preventive behavior was studied by means of mailed questionnaires. In all, 340 mothers, i.e. 95% of the sample, filled out and returned the forms. The results indicate a distinct and improving preventive attitude in the t... | 320,646 | [
0.06629518,
0.3709512,
-0.06219109,
0.1389964,
-0.1097372,
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-0.3209652,
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0.1110886,
0.003712185,
0.1468868,
0.1322002,
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0.1339812,
-0.14642,
0.4268722,
0.324764,
0.1509712,
0.06758123,
0.129... |
Ubiquity of R factor-mediated antibiotic resistance in the healthy population. | An attempt was made to assess the occurrence of R factor-mediated antibiotic resistance in the healthy population. Samples of aerobic, gram-negative intestinal bacteria from men from various parts of the country at military conscription were analysed for transferable drug resistance. The obtained frequency, about 15% o... | 320,655 | [
-0.01394415,
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0.1824728,
0.2149375,
0.0886514,
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0.04363142,
0.04029882,
0.01222194,
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0.3346325,
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0.004237896,
0.003958599,
0.1851139,
-0.027711,
0... |
A technique for closure of the lesser curvature of the stomach used in the von Eiselberg-Hofmeister reconstruction after subtotal gastrectomy. | A technique for closing the lesser curvature of the stomach after subtotal gastrectomy has been used in 847 subtotal gastrectomies. In this group, one patient had transient postoperative bleeding and none had anastomotic leakage. The technique is recommended as a simple method of obtaining a secure and hemostatic closu... | 320,692 | [
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Harvey Cushing: "From tallow dip to television". | Harvey Cushing was not only a leading founder of neurosurgery, but his work in general surgery provoked research which advanced medical knowledge, and he made substantial contributions to medical education and general literature. He discovered (with L.E. Livinggood) that the stomach and small intestine could be rendere... | 320,698 | [
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Heat illness. I. Epidemiology. | Reliable information on the epidemiology of heat illness has come, until recently, mainly from the armed forces and, to a lesser extent, from some industries and civil communities. Data from the records of the British Army, Royal Navy, Royal Air Force, Indian Armed Forces, U.S. Army and forces engaged in the Arab-Israe... | 320,723 | [
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0.152635,
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Volume limitations of plasmapheresis. | The published specifications of the acceptable limits of the maximum plasma volume to be "harvested" by plasmapheresis from one individual per year vary from 10-15 liters in Europe to 50-60 liters in the United States. To answer the question which of these widely diverging precepts is appropriate, the effects of plasma... | 320,764 | [
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0.3733764,
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The management of gonorrhea in an emergency room. | This study reviews the experience with gonorrhea and "pelvic inflammatory disease" in an emergency room of a university hospital. In spite of the large volume of critically ill patients seen in the emergency room, proper diagnostic methods and appropriate treatment for gonococcal disease were used by these physicians i... | 320,778 | [
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[Amniofetography in antenatal diagnosis of fetal abnormalities]. | The authors report the application of the amniofetography in the field of the antenatal diagnostic of fetale deformities. All pregnant women were investigated by Ultrasonic-B-scan. In cases of unambiguous hydramnios and in cases of pathological findings or findings which are not clear in Ultrasonic-B-scan an amniofetog... | 320,789 | [
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0.3996023,
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... |
Transfer factor and cellular immune response in urinary tract infections in children. | Cellular immune responses in vivo and in vitro were studied in 20 children with chronic or relapsing urinary tract infections. Skin tests revealed decreased immune responses to PPD in cases with chronic or recurrent pyelonephritis and to OM, in these cases and in cases of lower urinary tract infections. Blast transform... | 320,817 | [
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Characterization of Enterobacter agglomerans (Erwinia spp.) from clinical specimens. | The biochemical reactions of 18 anaerogenic and 45 aerogenic isolates of Enterobacter agglomerans are described and used for subdivision in the biogroups suggested by Ewing & Fife. The presence of special cultural characteristics (symplasmata and biconvex bodies) was also recorded and was found to be unrelated to f... | 320,820 | [
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0.3365671,
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Unchanged protein binding and the increase of serum diazepam levels after food intake. | Seven subjects received diazepam 0.3 mg/kg intravenously twice with a 2-week interval between the doses. The subjects ingested a fatty or carbohydrate meal in a cross-over fashion 4 hours after the injection on both experimental days. Venous blood samples were drawn 2, 3, 4, 5 and 6 hours after the injection of diazepa... | 320,825 | [
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0.07601832,
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0.2937219,
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0.3380878,
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-... |
Sleep disorders in patients with severe mental depression: double-blind placebo-controlled evaluation of the value of pipamperone (Dipiperon). | Pipamperone was compared double-blindly with placebo to evaluate its capacity to relieve sleep disorders in 40 depressive inpatients. At the end of the 1-week trial, most of the items relating to sleep disturbances had improved significantly in the 24 patients of the pipamperone group whereas only a few items showed su... | 320,830 | [
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0.1908407,
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0.02823385,
-0.09909043,
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0.3347885,
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0.1205177,
0.07798279,
0.08679783,
0.076844... |
The determination of anticonvulsants in biological samples by use of high-pressure liquid chromatography. | The procedure for anticonvulsant analysis represent use of a relatively new technology. The procedures compare favorably in accuracy and precision with accepted methodology using gas chromatography [14]. It is possible to determine a greater number of anticonvulsants simultaneously with liquid chromatography than with ... | 320,834 | [
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0.03840964,
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0.1348682,
0.2814358,
0.2707134,
0.1331337,
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... |
Engelmann and his laddergram. | Thomas Lewis is alliteratively credited with devising the laddergram. Engelmann, or perhaps Chauveau, truly deserves the honor. Mackenzie and Wenckebach popularized the schema in their books. | 320,858 | [
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-0.3041828,
-0.0283011,
0.3326418,
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Feeding preferences of Triatoma dimidiata maculipennis in Yucatan, Mexico. | To determine whether a low preference for human blood by Triatoma dimidiata maculipennis Stal, 1859, the only known vector of Chagas' disease in Yucatan, Mexico, would account for the low prevalence of antibodies to Trypanosoma cruzi in man in the area, the intestinal contents of 924 bugs were tested against antisera t... | 320,892 | [
0.0462908,
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0.01929592,
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0.1141902,
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0.2465065,
0.009264937,... |
Severe bronchial asthma: factors influencing intensive care management and outcome. | Over a seven year period 2933 patients were admitted with asthma. Respiratory failure occurred on 106 occasions. A total of 26 patients died including 11 of the 106 who developed respiratory failure. The intra-hospital management of asthma is outlined. The experience is analysed to indicate those patients particularly ... | 320,902 | [
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0.1970195,
0.03455786,
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0.02073331,
0.03698041,
-0.042... |
Ultrasound in renal transplantation. | Because of important differences in prognosis and treatment, prompt and accurate diagnosis of fever, decreasing function, and pain and tenderness around a renal allograft is crucial for differentiation between acute rejection and other post-operative conditions which may give a similar picture. Ultrasound examinations ... | 320,950 | [
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... |
Relaxation therapy and high blood pressure. | Thirty-one patients receiving medical treatment for essential hypertension were randomly distributed into three groups: (1) relaxation therapy, (2) nonspecific therapy, and (3) medical treatment only. The nonspecific therapy group spent the same amount of time with the therapists as the relaxation group but was not giv... | 320,955 | [
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0.1127781,
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0.03372975,
-0.1773025,
0.2769298,
-0.1195376,
0.0... |
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