title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Importance of the spleen for the immuno-inhibitory aciton of linoleic acid in mice. | Certain immuno-inhibitory effects of a polyunsaturated fatty acid, linoleic acid (C18:2), no longer occur after splenectomy of young adult CBA mice. This observation suggest that the spleen is a major intermediary in the action of C18:2 on the lymphoreticular system. Pathways of this action remain to be elucidated. Pos... | 323,155 | [
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A solid-phase radioimmunoassay for polyhedron protein from baculoviruses. | A solid-phase radioimmunoassay has been developed for detecting polyhedron protein of Wiseana spp. nuclear polyhedrosis virus (W.NPV) using antigen fixed to plastic microtiter wells. The direct assay using 125I-labeled rabbit immunoglobulins could detect 0.2 microng of polyhedron protein, and the indirect method using ... | 323,188 | [
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["Pseudoleukemia" in a newborn infant with trisomy 21]. | The increased incidence of leukemia in patients with trisomy 21 is well established. A blood disorder which may be mistaken for acute leukemia may occur in infants with trisomy 21. The authors report a newborn with trisomy 21 and hematologic findings suggesting acute leukemia (hyperleukocytosis, anemia, thrombocytopeni... | 323,201 | [
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Medium-dependent variation of deoxyribonucleic acid segregation in Escherichia coli. | The degree to which deoxyribonucleic acid segregates nonrandomly has been investigated for Escherichia coli B/r growing in different media. The degree of nonrandom segregation observed is dependent on the medium, with segregation becoming less random as the growth rate decreases. This indicates that there must be some ... | 323,220 | [
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Physiological regulation of a decontrolled lac operon. | The expression of the lac operon was studied under a variety of growth conditions in induced and in constitutive cells of Escherichia coli that carried different catabolite-insensitive lac promoters. Use of such "decontrolled" lac operons permitted a study of the expression of an operon that was presumably subject only... | 323,228 | [
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Growth and metabolism of inositol-starved Saccharomyces cerevisiae. | Upon starvation for inositol, a phospholipid precursor, an inositol-requiring mutant of Saccharomyces cerevisiae has been shown to die if all other conditions are growth supporting. The growth and metabolism of inositol-starved cells has been investigated in order to determine the physiological state leading to "inosi... | 323,239 | [
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Further characterization of the recipient ability of Escherichia coli K-12 bacteriophage-resistant mutants. | We extended the study of Escherichia coli mutants defective in conjugation and showed that the mutants with altered lipopolysaccharide, which are defective as recipients with F-like donors, are also defective with the I-like plasmid R64-11. However, the extent of reduction in recipient ability for I-like donors does no... | 323,242 | [
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Comparison of rabies humoral antibody titers in rabbits and humans by indirect radioimmunoassay, rapid-fluorescent-focus-inhibition technique, and indirect fluorescent-antibody assay. | Rabies humoral antibodies were induced in eight New Zealand rabbits by a single intramuscular injection of inactivated suckling mouse brain rabies vaccine. The primary response to immunization was measured in blood samples taken at selected intervals for 6 months. The anamnestic response was measured in blood samples o... | 323,278 | [
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Tellurite reduction test to aid in the recognition of Corynebacterium vaginale. | Corynebacterium vaginale (Haemophilus vaginalis) does not reduce potassium tellurite. When a 1% aqueous solution of tellurite is added to starch agar plates previously inoculated with vaginal discharge material, other starch-fermenting and most non-starch-fermenting bacteria rapidly reduce tellurite to produce black or... | 323,282 | [
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Double-blind comparison of triamterene plus hydrochlorothiazide and spironolactone plus hydrochlorothiazide in the treatment of hypertension. | The results from this double-blind, multi-investigator study showed that a combination of 50 mg triamterene plus 25 mg hydrochlorothiazide and a combination of 25 mg spironolactone plus 25 mg hydrochlorothiazide were equally efficacious in lowering blood pressure in hypertensive outpatients, and that they produced the ... | 323,298 | [
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Detection of functional complement components in gingival crevicular fluid from humans with periodontal diseases. | Crevicular fluid was collected from patients with periodontitis by a capillary tube procedure. Complement component activities were determined by functional assay systems, with human complement, and partially purified human first complement component (C1) as controls. The complement-fixing properties of the dental pla... | 323,317 | [
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Colloidal gold, a useful marker for transmission and scanning electron microscopy. | Electron dense markers of a size suitable for transmission electron microscopy and scanning electron microscopy have been prepared with gold granules labeled with a monolayer of specific macromolecules. The optimum conditions for preparing the markers have been ascertained. The method is simple, rapid and seems to be g... | 323,352 | [
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Labelling of lymphocytes with various radiosotopes for in vivo tracer studies; a review. | Several methods are available for labelling lymphoid cells with radioactive markers e.g. 3H, 14C, 125I, 131I, 35S, 75Se, based on general metabolic processes, involving DNA, RNA and protein synthesis in these cells. Together with methods for labelling lymphoid cells with 51Cr and 99mTc, radioisotopes which are captured... | 323,364 | [
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Emergence of resistance to chloramphenicol in salmonella. | Surveillance of antibiotic resistance of salmonella isolates from humans in the north-eastern United States has detected resistance to chloramphenicol on eight occasions, three of which were hospital outbreaks. Resistance was developed during treatment in five instances, and in another resistance this situation was sus... | 323,380 | [
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Agonist--antagonist interaction on dopamine receptors in brain, as reflected in the rates of tyrosine and tryptophan hydroxylation. | The effect of haloperidol and apomorphine, and both drugs in combination, on the first steps in the synthesis of catecholamines and 5-hydroxytryptamine (5-HT) has been studied in three rat brain regions. The rate of formation of dopa and 5-hydroxytryptophan (5-HTP) was studied by measuring the accumulation of these ami... | 323,424 | [
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A program to compute the sizes and numbers of spherical bodies from observations made on tissue sections. | A computer program, written in standard Fortran, is given to facilitate the computation of the sizes and correct distribution of spheres from the number and size of the circular profiles observed in tissue sections. The method is particularly valuable in cases where it is necessary to determine absolute numbers of cell... | 323,426 | [
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Effect of fat intake on cholesterol turnover and bile acid formation. | Three groups of male rats were maintained on diets containing different amounts of fat. After one week on such regimens, they were injected intraperitoneally with cholesterol-3H. During the following 28 days, the radioactivity and quantity of fecal cholesterol and its metabolities were determined. The coprostanol excre... | 323,430 | [
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Uptake and utilization of vitamin B6 and its phosphate esters by Escherichia coli. | Escherichia coli KG980, a vitamin B6 auxotroph derived from E. coli K12, utilized the three unphosphorylated forms of vitamin B6, more or less effectively, for growth, but did not utilize the three phosphate forms at concentrations ranging from 10(-7) to 10(-5) M in the minimum medium of Davis and Mingioli. The bacteri... | 323,431 | [
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Thymidylate synthetase inhibitors. Synthesis of N-substituted 5-aminomethyl-2'-deoxyuridine 5'-phosphates. | A series of substituted 5-aminomethyl-2'-deoxyuridines was synthesized as analogues of 5-thymidylyltetrahydrofolic acid, a proposed intermediate in the thymidylate synthetase catalyzed reaction. 1-(3,5-Di-O-p-toluoyl-2-deoxy-beta-D-ribofuranosyl)-5-chloromethyluracil (3) was treated with the appropriate amine to give t... | 323,484 | [
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Continuous-culture studies of interactions among human skin-commensal bacteria. | Chemostat studies were made of an antibiotic-producing Staphylococcus epidermidis strain (S6+), a similar, but antibiotic non-producing S. epidermidis strain (S6-), and a sensitive indicator strain of Micrococcus sp. (M7). Pure and mixed continous cultures were investigated at low population levels (in 0-1% peptone wat... | 323,493 | [
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Inhibition of bacteriophage M13 and phix174 duplex DNA replication and single-strand synthesis in temperature-sensitive dnaZ mutants of Escherichia coli. | A functional dnaZ product, known to be essential for host DNA polymerization and for the synthesis of M13 and phiX174 parental replicative-form (RF) DNA, is required also for RF replication and single-strand synthesis by both of these phages. All three stages of M13 and phiX174DNA replication (parental RF formation, RF... | 323,515 | [
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Diffuse histiocytic lymphoma. The need for aggressive restaging. | Fifteen patients with stage III and IV diffuse histiocytic lymphoma were treated with combination chemotherapy: cyclophosphamide, vincristine sulfate, prednisone, and procarbazine hydrochloride (COPP). Eight achieved a complete clinical remission. Of these, five relapsed, but remission was reinduced in three of these. ... | 323,527 | [
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Mitochondrial recombination in crosses of iso- and anisomitochondrial Saccharomyces cerevisiae. | Mitochondrial mutants resistant to erythromycin, neomycin and monomycin were isolated. Mitochondria were transmitted from different natural strains to the cells of the same nuclear genotype. In bifactorial crosses of such isochromosomal and anisomitochondrial yeasts we tested random samples of diploid colonies. The dis... | 323,686 | [
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[To the Treatment of myelomeningocele (author's transl)]. | Social importance of myelomeningocele specially in Great Britain is stressed and surgical treatment in 24 hours after birth is necessary. Severe complications as infections of the CNS and others in consequence of the neurogenic bladder are demonstrated. The manifold problems of these infants and their families need an ... | 323,782 | [
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Fever produced in the rat by intracerebral E. coli endotoxin. | E. coli endotoxin introduced into the brain ventricles or into various brain areas raises the body temperature of conscious rats. Endotoxin-sensitive sites were found within the anterior hypothalamus and the lower brainstem. The increase in temperature (delta T) after microinjection of endotoxin into the anterior hypot... | 323,816 | [
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A study of the effect of povidone-iodine on wound healing. | The effect of dry powder povidone-iodine (Disadine D.P.) on wound healing was assessed experimentally and clinically. It did not interfere with wound healing macroscopically, histologically or mechanically in Wistar rats. One hundred and one patients undergoing 'clean' elective surgery were included in the controlled c... | 323,835 | [
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Brain protein metabolism and the acquisition of new patterns of behavior. | Three cytoplasmic proteins (designated alpha, beta and gamma) in the goldfish brain consistently incorporated more labeled valine in animals that had acquired a new pattern of swimming behavior than in untrained animals. The changes were identified by double labeling techniques ([3H]valine injected into trained experim... | 323,861 | [
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Deltovertebral flap to cover a large scalp defect: case report. | A deltovertebral flap based on the perforating cutaneous branches of the posterior intercostal vessels (the exact opposite of the deltopectoral flap) was used successfully to cover a large scalp defect. The procedure is a rather hazardous one, due to the numerous stages and the awkward postoperative position. However, ... | 323,893 | [
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0.2254777,
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-0.1668522,
0.2542303,
0.2599907,
0.027894,
0.0294... |
Cross-arm triangular flaps for correction of adduction contracture of the first web space in the hand: case report. | We describe the use of two oppositely-based, triangular, cross-arm flaps for primary coverage of a new first web space, created by releasing an abduction contracture of the thumb. | 323,894 | [
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Prostaglandin biosynthesis and catabolism in the developing fetal sheep lung. | The prostaglandin biosynthetic and catabolic capacity of homogenates of lungs from fetal sheep of various gestational ages was measured. Prostaglandin biosynthesis was assayed by the deuterium-isotope dilution technique making use of mass fragmentography whereas prostaglandin catabolism was measured by the radioisotope... | 323,930 | [
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Some experimental surgical techniques on the alimentary tract of young pigs. | The paper describes the surgical techniques used in the preparation of gastric, intestinal and caecal fistulae, intestinal re-entrant fistulae, gastric pouches and Thiry-Vella loops. A total of 189 pigs were used in the study ranging from 1 h to 16 weeks of age. All procedures were carried out under cyclopropane/oxygen... | 323,949 | [
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Germination of Aspergillus fumigatus conidia in the lungs of normal and cortisone-treated mice. | Inhaled conidia of Aspergillus fumigatus germinated in the lungs of mice at a low rate but both germinated and ungerminated spores were cleared. Spores germinated at a high rate in the lungs of cortisone-treated mice. | 323,999 | [
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The wandering bullet. | Most bullets which enter the body usually exit or lodge within the soft tissues having traveled in a straight line. Management of such patients is usually a simple matter of repairing the injuries incurred during the passage of the bullet. Emphasis must be placed on the initial management of the patient and his life-th... | 324,004 | [
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[Retrospective analysis of the clinical relevance of the Kiel classification of malignant non-Hodgkin's lymphomas (author's transl)]. | 405 cases with non-Hodgkin's lymphomas have been diagnosed according to the Kiel classification and analysed retrospectively. 314 patients with non-Hodgkin's lymphomas of low-grade-malignancy (chronic lymphocytic leukemia, lymphoplasmacytoid, centrocytic, centrocytic, centroblastic-centrocytic lymphoma) manifested sign... | 324,031 | [
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Secretory capacity and ultrastructure of rat pancreatic islets after preservation of pancreas in different conditions. | Experiments were performed with rat pancreas to investigate optimum conditions for obtaining and preserving the pancreas for subsequent isolation of islets that were viable by both functional and morphological criteria. After only 30 min of warm ischaemia, the yield and viability of islets that could be isolated were p... | 324,042 | [
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Correlation of spontaneous leukocyte blastogenesis with human renal allograft rejection. | Spontaneous blastogenesis of peripheral blood mononuclear cells in recipients of renal allografts was studied by incorporation of 3H-thymidine. Three different levels of reactivity were observed that correlated with the patient's clinical course. Low levels of blast activity (i.e., median 680 dpm/million cells with 95%... | 324,046 | [
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0.0170... |
[Report of 100 total prostatectomies (author's transl)]. | A total retropubic prostatectomy is an exact, clearly defined operation, which, in our hands, has been extensively standardized: it lasts an average of 1 1/2 h, results in relatively little blood loss-in only 20% of the cases is one or more units of whole blood utilized-and is accompanied by complications that are kept... | 324,083 | [
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[Compensation for disordered functions and the problems of rehabilitative treatment of disabled veterans of World War II who suffered gunshot wounds of the upper extrememities]. | The data of dynamic observations and clincal examination of 128 invalids of the Great Patriotic War having gunshot wounds of the upper extremities after 20 years and longer evidence considerable improvement of the wounded extremity function and a reduced degree of disability in the late period due to compensatory pheno... | 324,109 | [
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[Experimental evaluation of a double-layer anastomosis of the large bowel in the dog following irradiation]. | In our experiments on dogs we study the influence of irradiation on large bowel surgery. 24 dogs were divided in two groups: the control and the irradiated group. The dogs were irradiated and after 4 months the resections of 5 cm of the irradiated large intestine was performed. We used single and double layer anastomos... | 324,203 | [
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0.1256241,
0.21072... |
[Pancreatic injuries]. | Within a constant increase in the number of injured in the last ten years a significant rise in the number of abdominal injuries has been noticeable. From 1,2% of ten years ago, abdomeninal injuries have risen to 4,6% of the total number of treated patients. While in earlier years pancreatic injuries were a rarity, in ... | 324,208 | [
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0.096051... |
[Our experiences in the treatment of burns using the technic of early necrectomy]. | In the last 10 years there were enough oppositions as regards time when to undertake surgical treatment. The tendency existed that the operation should be undertaken earlier. Tangentional excision and immediate covering of transplantations for deep dermal burns and burns the full thickness of the skin is surely the rig... | 324,211 | [
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Effect of minoxidil on blood pressure and hemodynamics in severe hypertension. | Eighteen patients with diastolic hypertension (100 to 120 mm Hg), in addition to propranolol, 160 mg daily, and hydrochlorothiazide, 100 mg daily, received progressively increased doses of either minoxidil or placebo in a double-blind crossover study. With minoxidil (average dose 19.7 mg) blood pressure decreased from ... | 324,257 | [
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Metabolic regulation as a control for lipid disorders. I. Influence of (--)-hydroxycitrate on experimentally induced obesity in the rodent. | The feasibility of treating obesity by metabolic regulation has been explored in this study by examining the effect of (--)-hydroxycitrate on three types of experimentally induced obesity in the rodent.(--)-Hydroxycitrate was utilized because it depressed fatty acid and cholesterol synthesis in vivo through its activit... | 324,261 | [
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Review of current knowledge of plastic intravenous fluid containers. | A review of the features of plastic intravenous fluid containers is presented. The following topics are discussed: (1) handling and storage; (2) environmental and human contamination; (3) particulate matter; (4) water vapor transmission; (5) drug additives; (6) leaching and adsorption; (7) possible toxicity; and (8) co... | 324,274 | [
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Involvement of a humoral factor in regulation of body weight in parabiotic rats. | Excessive food intake and obesity was induced in one member of parabiotic pairs by electrical stimulation (three 30-min sessions/day for 2 wk) of the lateral hypothalamus (LH). The nonstimulated partners reduced spontaneous food intake the fatter the stimulated animals became. This reduced food intake resulted in a dec... | 324,294 | [
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Islet cell hyperplasia localized by pancreatic vein catheterization and insulin radioimmunoassay. | A patient with organic hypoglycemia but with normal pancreatic arteriography was investigated with pancreatic vein catheterization for insulin immunoassay. Very high insulin concentrations (1, 130 micronU/ml) were found in a vein draining part of the pancreatic tail. Even though no tumor was found at operation, distal ... | 324,299 | [
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Ultrastructural and physiological studies of the stalk-sectioned rat pituitary gland. | A pituitary stalk-section rat model was prepared that would be suitable for the study of the direct effects of steroids on the pituitary gland. In this model, the hypophyseal stalk was severed surgically and metal foil was inserted to prevent regeneration of portal vessels. The major portion of the pituitary no longer ... | 324,326 | [
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Congenital chloride diarrhoea. Clinical analysis of 21 Finnish patients. | Clinical findings in 21 Finnish children with congenital chloride diarrhoea are reported. Inheritance of this disease by the autosomal recessive mode is established. All children were born 1-8 weeks prematurely. Hydramnios was present in every case and no meconium was observed; intrauterine onset of diarrhoea is thus a... | 324,405 | [
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[Use of methods of spectral-correlation analysis for studying the temporal and spatial organization of tissues]. | Tissues within the organism represent multidimensional systems organized in time and space and having statistical dispersion in each parameter. Changes in its state may have a character of a monotonous trend and be periodical (the matter of chronobiology). The methods for detection of latent periodicities, developed in... | 324,442 | [
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Recurrent basal cell carcinoma of the facial region -- a clinico-pathological challenge. | The observation that the majority of patients with basal cell carcinomas of the face presenting for surgical treatment did previously have radiotherapy or have undergone inadequate excision due to cosmetic considerations of the surgeon, induced us to review our own case material. According to this reassessment, a conce... | 324,459 | [
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An immunofluorescent method using Crithidia luciliae to detect antibodies to double-stranded DNA. | The immunochemical specificity of the immunofluorescent Crithidia luciliae method for detection of antibodies to double-stranded DNA (dsDNA) was confirmed by demonstrating abolition of staining by DNase digestion and by absorption with dsDNA. This method was less sensitive than a Millipore filter method for detecting a... | 324,482 | [
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Heparin-induced release of lipase activity in the human forearm: an immunological study. | Low doses of heparin were injected into the brachial artery of three volunteers. The lipase activities in the deep vein of the same forearm, draining mainly muscle tissue, and in the artery were monitored over a 10-min period. Lipase activity, rapidly released by heparin in the deep vein, was immunologically similar to... | 324,491 | [
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Comparison of lidoflazine and quindine in prophylactic treatment of arrhythmias. | The efficacy of quinidine versus lidoflazine therapy was compared in the maintenance of sinus rhythm after electrical cardioversion for atrial flutter or fibrillation in a group of 35 patients. Both quinidine and lidoflazine were relatively ineffective in maintaining sinus rhythm after cardioversion. Lidoflazine was al... | 324,502 | [
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0.278723,
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Erysipelas and necrotizing fasciitis. | The clinical course of necrotizing fasciitis in 8 patients is compared with observations on 22 other patients with erysipelas. In necrotizing fasciitis the early erythematous areas turn into a dusky blue colour with later vesiculation and formation of bullae. An important finding is a non-pitting oedema extending outsi... | 324,513 | [
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0.2412076,
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-0.14... |
[Isotherms of globular protein hydration under dynamic conditions]. | The hydration isotherms of alpha-chymotrypsin, lysozyme, pork insulin, pork pepsin and serum albumin were obtained by means of dynamic method. The values of BET-monolayers for processes of water sorption leads to (h) and desorption comes from (h) do not depend on the static or dynamic way of achieving of hydration equi... | 324,524 | [
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0.09934407,
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Pulmonary surfactant and dog lung transplant. | The pulmonary sufactant was studied in the dog after crossed lobe autotransplantation and the influence of graft preservation time before reimplantation was considered. 1) The phospholipid composition of the grafted lobe is unchanged. 2) The incorporation of 32P orthophosphate in phosphatidylcholines is increased in th... | 324,532 | [
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0.137983,
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0.5194569,
-0.04550817,... |
Study of the correlation between glomerular and urinary sediment deposits using immunofluorescent technique. | Correlations between immunofluorescent protein deposits in the glomeruli, urinary sediment and proteinuria selectivity pattern have been attempted in different glomerulonephritis. The overall study showed following results: a) Glomerular and urinary casts deposits of immunoglobulins, C3 and fibrin/fibrinogen are relate... | 324,533 | [
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Cell marker analysis in acute monocytic leukemias. | Leukemic cells from nine cases of acute monocytic leukemia (AMoL) were characterized by multiple differentiation markers. Cells in most cases were phagocytic, carried an Fc receptor, and stained positively for alpha-naphthyl acetate esterase but negatively for naphthol AS-D chloroacetate esterase. However, subtle diffe... | 324,537 | [
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Allergy testing: comparison of skin and in vitro tests of allergic reagin. | Skin tests have been used for many years to detect reaginic antibodies in the investigation of allergic patients. Recently in vitro assays of allergic reagins, including the radioallergosorbent test (RAST) and the rat mast cell test (RMCT) have become available. A comparison of the clinical usefulness of these tests su... | 324,590 | [
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Antibody formation by human tonsil cells in vitro. | The ability of human tonsil lymphocytes to give an anti-SRBC response in conventional cultures and in microcultures was studied. It was found that about two-thirds of tonsils responded with a significant number of plaque-forming cells (PFC), and that in some instances the response could be augmented if allogeneic tonsi... | 324,673 | [
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Immunological studies in the neonate of a mother with Addison's disease and diabetes mellitus. | In a baby born to a mother who had idiopathic (autoimmune) Addison's disease and gestational insulin-dependent diabetes, antibodies to adrenal cortex and to pancreatic islet cells were demonstrated in the cord blood and serum for at least 41 days. There was no clinical or objective evidence of adrenocortical failure or... | 324,676 | [
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Myosin autoantibodies detected by immunofluorescence. | Autoantibodies to striated and smooth muscles myosins were detected by indirect immunofluorescence and confirmed by absorption with purified contractile proteins extracted from human, rabbit and chicken muscle. Myosin antibodies were rare: of fifty-five sera examined from patients with various skeletal and cardiac musc... | 324,677 | [
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Plasma protein binding of phenytoin and warfarin in patients undergoing renal transplantation. | The plasma protein binding of phenytoin and warfarin was studied in vitro by equilibrium dialysis at 37 degrees C in plasma from patients with chronic renal disease before and after renal transplantation. The plasma protein binding of these two drugs (which is decreased in the uraemic state), increased dramatically dur... | 324,689 | [
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[Critical considerations on the development of composite filling materials]. | Following the report given at the FDI congress in Chicago in 1975, the question is raised about the present state of acrylic filling materials, i.e. whether further developments are necessary or even possible. The importance of clinical testing is emphasized and the problems involved in chemical binding to the dental h... | 324,752 | [
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Magnesium modulation of glucose-induced insulin secretion by the perfused rat pancreas. | Increasing levels of magnesium were found to cause a marked depression of glucosestimulated insulin secretion at fixed calcium levels, particularly at levels which bracketed the concentration of ultrafiltrable magnesium found in normal rat plasma (1.3 meq/l), i.e., increasing magnesium from 0.6 to 1.2 meq/l depressed s... | 324,755 | [
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Localization of hormone secreting pathways in the brain by immunohistochemistry and light microscopy: a review. | Immunocytochemical techniques are now being used to localize hypothalamic neurosecretory hormones and related peptides in the mammalian brain. The data are probably incomplete, due primarily to false negative results. A number of previous assumptions concerning these pathways have been confirmed while other unexpected ... | 324,815 | [
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Steroid hormone target cells in the periventricular brain: relationship to peptide hormone producing cells. | Steroid hormone concentrating cells in hypothalamic and extrahypothalamic regions are reviewed and the topographic relationship to the periventricular brain and the ventricular recess organs is discussed. Steroid hormone target cells in the brain are considered feedback sites and production sites of polypeptide hormone... | 324,816 | [
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The effects of long-term therapy with oral hypoglycemic agents on the oral glucose tolerance test dynamics in male chemical diabetics. | The effect of fixed doses of oral hypoglycemic agents and placebo (diet alone) on the blood glucose, serum insulin, triglyceride, and cholesterol responses during oral glucose tolerance tests done annually for up to four years' follow-up was studied, in a double-blind manner, in five groups of mild male chemical diabet... | 324,835 | [
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Effect of anti-thymocyte serum, anti-macrophage serum, and latex particles on the therapeutic efficacy of BCG or Corynebacterium liquefaciens (Propionibacterium acnes C7) in syngeneic mice. | In a syngeneic mouse-tumor system, anti-thymocyte serum, anti-macrophage serum, and latex particles were used for a comparative study of the immunotherapeutic efficacy of intradermal inoculation of tumor cell-BCG and tumor cell-Corynebacterium liquefaciens (=Propionibacterium acnes C7) vaccines. Anti-thymocyte serum tr... | 324,858 | [
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Improved infusion system for intraluminal esophageal manometry. | An improved catheter infusion system is needed for esophageal intraluminal manometry. Using conventional syringe-pump infusion systems undesirably rapid infusion rates of 6 ml per min or more are often needed to achieve accurate recording of esophageal peristaltic pressure. These rapid base line infusion rates are nece... | 324,861 | [
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Association of chromosome loss with centromere-adjacent mitotic recombination in a yeast disomic haploid. | Experiments designed to characterize the association between disomic chromosome loss and centromere-adjacent mitotic recombination were performed. Mitotic gene convertants were selected at two heteroallelic sites on the left arm of disomic chromosome III and tested for coincident chromosome loss. The principal results ... | 324,869 | [
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Antigenic competition between heterologous erythrocytes in mice. Immunological and histological studies exploring mechanisms of the antigenic competition. | To explore the mechanisms of antigenic competition, immunological and histological studies were made on mice using non-crossreacting heterologous erythrocyte antigens, i.e. sheep (SRBC), horse (HRBC) and chicken (CRBC) erythrocytes. Deficiency in the competition-inducing capacity of CRBC which we demonstrated in a prev... | 324,903 | [
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Inhibition of small-intestinal sugar and amino acid transport by the enterotoxin of Shigella dysenteriae I. | The enterotoxin of Shigella dysenteriae I produces fluid and electrolyte secretion in the rabbit ileum. These present studies were designed to evaluate nonelectrolyte transport in rabbit ileal mucosa exposed to Shigella enterotoxin. Both 10 mM galactose and 5 mM L-alanine absorptions were significantly impaired in ente... | 324,910 | [
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Anti-T cell activity of niridazole in experimental autoimmune encephalomyelitis. | The antischistosomal drug niridazole, known to selectively depress cell-mediated immune function, was assessed in experimental autoimmune encephalomyelitis (EAE) in mice. EAE results from an immune attack by activated T lymphocytes on the central nervous system. Niridazole given orally at a dose of 100 mg/kg body weigh... | 324,924 | [
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[Formation of covalent linkages between the nucleic acid and protein constituents of E. coli MRE 600 ribosomes during gamma irradiation]. | Gamma-irrdiation of E. coli MRE 600 ribosomes in aqueous suspensions leads to covalent linkages between the RNA and some ribosomal proteins. The presence of oxygen during the irradiation strongly inhibits this phenomenon. It appears clearly that only a few proteins are able to participate in these cross-linking reactio... | 324,935 | [
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[Plastic surgery of lower lip defects (author's transl)]. | A modification of the Hertig method for reconstruction of the lower lip is reported. The method is suitable for repair of lateral defects of the lower lip, and was performed in 10 patients. The procedure is technically simple to perform, and yeilds good functional and cosmetic results. | 324,953 | [
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Genetics of sensitivity of Salmonella species to colicin M and bacteriophages T5, T1, and ES18. | Nearly all of 62 strains of Salmonella paratyphi B were sensitive to colicin M and phage T5 but resistant to phages T1 and ES18 and to colicin B. All tested S. typhimurium strains were resistant to colicin M and phage T5, and many were sensitive to phage ES18. A rough S. typhimurium LT2 strain given the tonA region of ... | 324,978 | [
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Deoxyribonucleic acid strand breaks during freeze-drying and their repair in Escherichia coli. | Freeze-drying of Escherichia coli cells caused strand breaks of deoxyribonucleic acid (DNA) in both radiation-sensitive and -resistant strains. However, in the radiation-resistant strain E. coli B/r the damaged DNA was repaired after rehydration, whereas in the radiation-sensitive strain E. coli Bs-1 the damaged DNA wa... | 324,987 | [
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Use of 3H and 14C double-labeled glucose to assess in vivo pathways of amino acid biosynthesis in Escherichia coli. | 3H and 14C tracing data concerning amino acid biosynthetic pathways in Escherichia coli K12 are presented. Thirteen acidic and neutral amino acids were isolated from protein hydrolysates of wild type E. coli K12 grown aerobically or anaerobically in the presence of [U-14C]glucose together with [1-3H]glucose, [3-3H]gluc... | 324,995 | [
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Colostral cell-mediated immunity and the concept of a common secretory immune system. | Historically colostrum and milk have been thought to confer immunity on the neonate only by virtue of their immunoglobulin content. Recently we have observed that colostrum also contains viable T lymphocytes capable of expressing cell-mediated immunity in vitro and have employed techniques of lymphocyte culture to eluc... | 325,032 | [
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Pulmonary oedema associated with hydrocarbon inhalation. | A patient with gross pulmonary oedema secondary to inhalation of paint fumes is described. Treatment with mechanical ventilation and positive end expiratory pressure was required. | 325,051 | [
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Technique for the fabrication of a cast post and core with nonprecious metal. | A technique for the construction of a cast post and core with a nonprecious metal is described. The technique is a practical and inexpensive approach to the construction of this type of restoration. | 325,052 | [
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Current publications in gerontology and geriatrics. | THE SUBJECT categories are those in A Classified Bibliography of Gerontology and Geriatrics by Nathan W; Shock, published by Stanford University Press, Stanford, California (1951). Only major headings are used and the Roman numerals correspond to those given in the bibliography. Insofar as possible, references are clas... | 325,062 | [
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Salmonella surveillance with reference to pigs--Cardiff abattoir, 1968-1975. | Between 1968 and 1975, well over 3000 samples of pig faeces and 407 samples of pig mesenteric glands were examined for salmonellas. A very wide range of serotypes was isolated. The material from this survey was used to evaluate certain aspects of salmonella isolations. The factors studied were: selective motility enric... | 325,128 | [
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-0.4368664,
0.03583564,
0.3037358,
-0.1522989,
-0.1604559,
0.09304532,
-0.1019223,
0.3031784,
0.02985771,
-0.232283,
-0.1653849,
-0.4946519,
-0.1116718,
-0.06964274,
0.3526907,
0.3540901,
-0.1704661,
0.1700618,
... |
Acute ascending polyradiculoneuritis in a case of Creutzfeldt-Jakob disease. | A patient is described who showed subacute dementia and ataxia and, finally, acute asending polyradiculoneuritis. At necropsy, together with the cerebral and cerebellar lesions that are typical of Creutzfeldt-Jakob disease, the lesions of the spinal motor neurons, the spinal ganglia, and of the roots and peripheral ner... | 325,182 | [
-0.06136459,
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0.02097047,
-0.1745833,
0.06103252,
0.1142134,
-0.07905988,
0.04064... |
Failure of adjuvant immunotherapy to prevent central nervous system metastases in malignant melanoma patients. | A review of our experience using BCG immunotherapy as a postsurgical adjunct in the treatment of melanoma shows that the incidence of systemic metastases appears to have been reduced. However, central nervous system (CNS) metastases continue to develop in these patients and represent the single most frequent cause of d... | 325,299 | [
-0.1373139,
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0.3169058,
0.01575193,
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0.06312525,
0.... |
Characterization of an E. coli mutant with a thermolabile initiation factor IF3 activity. | A thermosensitive E. coli mutant is described which has at least two defects in vitro: a thermolabile initiation factor IF3 activity and a modified L-phenylalanine: tRNAPhe ligase (EC 6.1.1.20) activity. These two defects cotransduce and are located near 38 min on the new E. coli map. Thermoresistant revertants showing... | 325,363 | [
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0.3054906,
0.1664725,
0.2881326,
-0.0111733... |
Induction of protein synthesis in Escherichia coli following UV- or gamma-irradiation, mitomycin C treatment or tif Expression. | The rate of synthesis of total cellular proteins has been studied by pulse labelling cells at various periods after irradiation with UV or gamma-rays, after treatment with mitomycin C (MMC) or after expression of the temperature sensitive mutation tif. Subsequent gel electrophoresis and autoradiography reveals changes ... | 325,368 | [
0.0830166,
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0.2393482,
0.3311512,
0.229977,
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0.... |
Growth and reactivation of single stranded DNA phage phiX174 in E. coli undergoing "thymineless death". | The thymine requirement of the E. coli strain HF 4704 (uvr A-, rec A+) is thermosensitive i.e. these cells require for their growth 2 microng thymine per ml at 37 degrees C but not at 30 degrees C. Such cells when starved for thymine for 3 h at 37 degrees C are capable of sustaining growth of single stranded DNA phage ... | 325,376 | [
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0.1968159,
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0.1351084,
0.4153162,
0.2780947,
-0.05766422,
-0.04... |
Identifying sites of simultaneous DNA replication in eukaryotes by N-methyl-N'-nitro-N-nitrosoguanidine multiple mutagenesis. | N-methyl-N'-nitro-N-nitrosoguanidine (NG) induces certain classes of multiple mutations in yeast at high frequency. By selecting for mutation at one locus (his4 or leu1) one frequently obtains double mutants where another mutation to temperature sensitivity has also been induced. This multiple mutagenesis exhibits a co... | 325,387 | [
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0.3228672,
0.1832513,
0.4281708,
0.3339657,
-0.1710996,
... |
Relation between the race and economic status of patients and who performs their surgery. | We evaluated the relation between race and economic status of surgical patients and their likelihood of being treated by a surgeon in training rather than by a staff surgeon. Blacks were 2.2 to 4.3 times more likely than whites to be under the care of surgeons in training (P less than 0.001). This relation has remained... | 325,411 | [
0.1746736,
0.1656784,
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0.1039836,
0.102112,
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0.06055321,
0.08486466,
-0.04156202,
-0.2061863,
... |
Platelets and glomerulonephritis. | There is evidence derived from both experimental studies and from observation of human nephritis that platelets are important in the glomerular injury of chronic soluble-complex disease. It is not yet clear if platelets are involved in the events initiating endothelial damage, in perpetuating and amplifying injury, or ... | 325,428 | [
-0.2160936,
0.2980344,
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-0.1744027,
0.0819831,
0.003827679,
0.3287939,
0.05955178,
0.002098297,
-0.077... |
An Aeromonas species implicated in ulcer-disease of the cod (Gadus morhua). | Vibrio anguillarum is the most frequently isolated bacterial species involved in ulcer disease in salt water fish. However, an Aeromonas species was very often incriminated in ulcers and septicaemia in cods (Gadus morhua) in Danish coastal areas. These Aeromonas strains were very uniform in their biochemical activities... | 325,501 | [
-0.2672603,
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0.3308268,
0.09981902,
0.5730398,
0.3472387,
0.07519925,
-0.3076... |
The sequence specificity of a mammalian DNA methylase. | The sequence specificity of an extensively purified DNA methylase preparation from Krebs II mouse ascites cells has been examined. The enzyme appears to be highly sequence dependent. Moreover the sequence distribution of cytosine residues that are methylated, bears a very close resemblance to the sequence distribution ... | 325,523 | [
0.1096211,
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0.1491071,
0.02666448,
0.2594923,
0.2003739,
-0.03015988,
-0.2895543,
0... |
Synthesis of oligonucleotides with sequences identical with or analogous to the 3'-end of 16S ribosomal RNA of Escherichia coli: preparation of A-C-C-U-C-C via the modified phosphotriester method. | A combination of two different methods for the synthesis of oligoribonucleotides, i.e. the two-step phosphotriester method with 2-chlorophenyl phosphate as bifunctional phosphate source and the modified triester method with 2,2,2-trichloroethyl 2-chlorophenyl phosphorochloridate as monofunctional phosphate source, is a... | 325,524 | [
-0.3500237,
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-0.2250711,
0.0883823,
-0.2897278,
0.211403,
0.2891853,
0.05474121,
-0.1421197,
... |
Endogenous E. coli endophthalmitis. | A case of Escherichia coli septicemia with associated metastatic en dophthalmitis and endocarditis is presented. The ocular signs and symptoms were the initial manifestations of sepsis. Irreversible damage to the eye occurred in less than 24 hours. The pattern of metastatic bacterial endophthalmitis has changed since t... | 325,673 | [
-0.3525386,
0.1168878,
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-0.6026598,
0.2702981,
0.3903596,
-0.2268205,
0.3230661,
0.4892957,
-0.06231435,
... |
[Indication and assessment of preprosthetic-surgical technics from the prosthodontist's viewpoint]. | The functioning of a complete lower denture is determined by a series of clinico-anatomical characters of the edentulous mandible. These are commented upon to establish the limits of indication of preprosthetical-surgical techniques. The reflections point to the necessity for paying more attention to really reconstruct... | 325,699 | [
0.1033142,
0.1296899,
-0.1208011,
0.2191216,
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0.1192775,
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-0.3357168,
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0.1478009,
0.06629857,
-0.07738601,
0.3257574,
0.06350722,
0.3044233... |
[Functional disorders following resection of the tongue and mouth floor]. | On observing 20 patients who had underwent total tongue and floor-of-the-mouth resection, the authors stated difficulties in swallowing and breathing that in certain cases called for laryngectomy. To counteract these disorders, floor-of-the-mouth and tongue reconstruction was performed with the aid of an arterialized f... | 325,700 | [
-0.1024216,
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0.2521775,
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-0.02279774,
0.08527621,
0.2999871,
-0.09341422,
-0... |
Relation of immediate post-transplant renal function to long-term function in cadaver kidney recipients. | Renal function studies 12 to 41 months after transplantation have been performed on seven cadaver renal allograft recipients who demonstrated immediate primary function after transplant (group A) and seven similar recipients who had delayed primary function (group B). The groups were matched as closely as possible for ... | 325,704 | [
0.007734914,
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0.2778139,
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0.2031021,
0.110281,
0.1904366,
0.2054603,
0.4241444,
-0.2310... |
[Role of several physico-chemical surface properties of bacteria in the machanism of the initial phases of phagocytosis]. | An attempt was made on E. coli pattern to reveal the role played by the surface charge and the extent of the surface hydration in the mechanism of the initial phagocytosis phases (attraction and submersion). Phagocytosis experiments with washed bacteria and washed rabbit leukocytes demonstrated a marked direct dependen... | 325,969 | [
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-0.3295403,
0.08236502,
0.1206238,
0.1145993,
0.308066,
0.03083408,
-0.081... |
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