title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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The outcome of hepatitis B virus infection in pregnancy. | The literature concerning hepatitis B in pregnancy is reviewed and problems of management of both the acute and chronic infections are discussed. | 339,213 | [
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A comparison of once and twice daily atenolol in hypertension. | The hypertensive action of atenolol has been studied in a randomized double-blind crossover comparison. Twelve patients showed a highly significant reduction in average supine systolic and diastolic blood pressures from pre-treatment values of 196.3/115.9 to 159.1/89.2 mmHg (26.1/15.4 kPa to 22.2/11.9 kPa) after 2 week... | 339,214 | [
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[Recovery from apparently hopeless fresh-water drowning (author's transl)]. | Report of 3 cases of drowning (children). 2 patients survived without severe injury, 1 patient died after 13 days. The protective action of hypothermia to the brain and heart in hypothermic drowning is emphasized. Even in apparently hopeless cases resuscitation should be started immediately and should not be discontinu... | 339,220 | [
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Tissue reactions to breast implants coated with polyurethane. | The histological features noted in the capsules from 7 polyurethane coated silicone breast prostheses are described. The polyurethane provoked a definite foreign body reaction and was slowly degraded, with some particles ejected from the capsule into the surrounding tissues. Separation of the polyurethane coating from ... | 339,248 | [
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The effect of various adjuncts on the surgical treatment of carpal tunnel syndrome secondary to chronic tenosynovitis. | A series of 22 patients with carpal tunnel syndrome secondary to chronic tenosynovitis was divided into two groups. The first group was treated by transverse carpal ligament release alone. The second group was treated by transverse carpal ligament release, external neurolysis of the median nerve, flexor synovectomy, a... | 339,250 | [
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Pulmonary complications of renal transplantation: a survey of patients treated by low-dose immunosuppression. | Sixty-eight episodes of pulmonary complication developed in 52 of 416 renal transplant recipients treated with low-dose immunosuppression. Twenty-four complications were noninfectious (20 were pulmonary edema due to transplant rejection). Forty-four complications were infectious (75% of were wholly bacterial). Nine pat... | 339,267 | [
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[Effect of beta and alpha-lapachone on the production of H202 and on the growth of Trypanosoma cruzi]. | Addition of beta-lapachone to the epimastigote (culture) form of Trypanosoma cruzi, suspended in saline, buffered-isotonic medium (pH 7.2), determined the appearance of large amounts of H2O2 in the suspension medium, as measured spectrophotometrically by formation of the H2O2 horse radish peroxidase complex. Under simi... | 339,293 | [
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Rat gastric secretion and mucosal blood flow during restraint stress--effect of a low dose metiamide. | In rats under either mild stress (= controls) or severe stress (= restraint) gastric secretion (acid; pepsin, volume), mucosal blood flow, serum gastrin and ulcer formation were evaluated without and with additional infusion of a low dose (0.25 mg/kg.h) metiamide over an 8 h experimental period. Calculated constants of... | 339,307 | [
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Canine kidney preservation: comparison of "intracellular", "extracellular," and high molecular weight dextran flushing solutions. | The effects of modified Collins-2 solution, adjusted lactated Ringer's solution, and a solution containing dextran 70 on kidney preservation and red blood cell (RBC) washout in dogs were evaluated. Excised kidneys were stored on ice for 24 hours and then reimplanted, at which time the contralateral kidney was removed. ... | 339,359 | [
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[Use of nuclear-medicine technics in the differential diagnosis of anemias]. | The use of nuclear-medical methods is especially described for the diagnostic of anaemias with different etiology. For the diagnosis of the chronic haemorrhagic anaemias the determination of the blood losses through the gastrointestinal tract with the help of the 51Cr-method and for the course of the acute haemorrhagic... | 339,566 | [
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[Tumours of the skin (author's transl)]. | Clinical oncology as an interdisciplinary subject demands as intensive cooperation in the treatment of tumours of the skin between the dermatologist, the radiologist, and the surgeon. A survey is presented on the systemic order of tumours of the skin especially regarding the differential diagnosis and the surgical trea... | 339,603 | [
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[Clinico-immunological characteristics of dysentery in persons with different blood groups]. | The authors studied the frequency of distribution of the ABO system blood groups in 392 adults and 322 children suffering from acute dysentery. X2 criterion and double-factor dispersion analysis were used for statistical analysis. Deficiency of persons with B III and AB IV blood group. Phagocytosis indices were decreas... | 339,628 | [
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Circulatory reflex responses during the initial stage of feline endotoxin shock. | Cardiovascular and autonomic nervous responses to an injection of E. coli endotoxin were followed for up to 15 min. in cats anesthetized with chloralose and given artificial respiration. Within 60 seconds, endotoxin induced a drop of aortic pressure, with simultaneous cardiac acceleration and slight central venous hype... | 339,668 | [
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An improved technic for examining urinary casts and a review of their significance. | Casts represent an important, diagnostic component of urinary sediment, and may signal renal parenchymal disease in asymptomatic individuals. Accurate, precise identification of certain casts may be difficult due to poor visualization by current technics. Casts from freshly voided urine specimens, cytocentrifuged and s... | 339,708 | [
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Content of luteinizing hormone-releasing factor in the human placenta. | Immunoreactive luteinizing hormone-releasing factor (LRF) was quantitated in the human placenta. It was found that the total placental content as well as the content per milligram of placental tissue varied with the stages of gestation. The fetal sex did not affect the LRF production. These studies establish that the p... | 339,717 | [
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Results of intraocular lens implant surgery. The third Binkhorst medal lecture. | I compared an early series of 162 consecutive Copeland intraocular lens implants with a later series of 650 consecutive Binkhorst implants. Of the eyes with Copeland implants, 76.5% achieved 6/12 (20/40) or better visual acuity compared to 89.8% in the Binkhorst series. There was a striking difference in the incidence ... | 339,724 | [
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The effects of indomethacin on the generalized shwartzman reaction. | The antiflammatory drug indomethacin, an inhibitor of prostaglandin synthesis, prevents the generalized Shwartzman reaction produced in rabbits by two intravenous injections of bacterial endotoxin. Indomethacin has this effect if given before the first but not the second injection of endotoxin. Measurements of circulat... | 339,745 | [
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Vascular access for chronic hemodialysis: polytetrafluoroethylene (PTFE) versus bovine heterograft. | Between May 1975 and March 1977, 193 bovine heterografts and 184 polytetrafluoroethylene (PTFE) grafts (Impragrafts) have been placed for hemodialysis access. A comparison of these materials demonstrates that Impragrafts have significantly fewer late thromboses, increased resistance to infection, and comparable longevi... | 339,765 | [
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Comparison of real and simulated acupuncture and isoproterenol in methacholine-induced asthma. | In a double-blind (patient and evaluator), crossover study effects of real acupuncture, simulated acupuncture, nebulized isoproterenol, nebulized saline and no treatment in reversing methacholine-induced bronchospasm were compared in 12 asthmatics (ages 16 to 64). Saline and simulated acupuncture did not result in any ... | 339,785 | [
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Double-blind one-year clinical study of fenoterol metered dose inhaler: preliminary results of a cooperative study. | As part of a controlled multi-center study 44 chronic asthmatics were treated for one year with either fenoterol (0.4 mg t.i.d. or q.i.d.) or isoproterenol (0.15 mg t.i.d. or q.i.d.) by metered dose inhaler. According to spirometric tests, fenoterol significantly improved pulmonary function until the end; isoproterenol... | 339,787 | [
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[Psychological approach to Céline's obscenity]. | The aim of the psycho-analytical approach the author attempts is the obscene character of Céline's dependent of the writer's whole personality. The obscenity of the celinian language proceeds from several causes. It can be explained by the lucid and the phallic-narcistical features of Céline's personality in relation w... | 339,805 | [
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Microbial metabolic activity in soil as measured by dehydrogenase determinations. | The dehydrogenase technique for measuring the metabolic activity of microorganisms in soil was modified to use a 6-h, 37 degrees C incubation with either glucose of yeast extract as the electron-donating substrate. The rate of formazan production remained constant during this time interval, and cellular multiplication ... | 339,829 | [
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Macromolecule synthesis of Escherichia coli BB at a lower or transient growth state. | Macromolecule synthesis in Escherichia coli BB at lower growth rates was investigated. The results indicate that a deviation in ribonucleic acid (RNA) content per cell at a lower growth rate from the exponential relationship to a specific growth rate is entirely attributable to the presence of nonviable cells, in which... | 339,834 | [
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Double-stranded ribonucleic acid in viruses of Penicillium citrinum. | The nucleic acid content of two viral populations in a strain of Penicillium citrinum is shown to be double-stranded ribonucleic acid, resolved through polyacrylamide gel electrophoresis into 10 size groups ranging from 1.17 to 3.98 megadaltons. | 339,838 | [
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Viability of Rhizobium bacteroids. | Bacteroids prepared from nodules of soybean and bean were tested for viability. Contrary to the prevailing view that bacteroids are nonviable, it was found that bacteroids averaged 90% viability, irrespective of Rhizobium strain, nodule age, or nodule environment. | 339,840 | [
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Interrupted aortic arch complex: successful total correction in the neonate. | Two neonates subjected to definitive repair of interrupted aortic arch complex during the first week of life are presented. Results correlated well with preoperative status. Our definition of complete correction, including direct aortic anastomosis, is discussed along with the surgical strategy employed for successful ... | 339,863 | [
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Ticrynafen: a novel uricosuric antihypertensive natriuretic agent. | Interest in new diuretics with less side effects has led to the synthesis of ticrynafen, an uricosuric diuretic. This agent was compared with hydrochlorothiazide in a crossover design study involving 12 hypertensive men. Both agents significantly decreased mean arterial pressure from 8% to 18% in eight of the 12 patien... | 339,865 | [
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Induction of lymphokines by tilorone. | Serum obtained 16 hr after p.o. application of tilorone [2, 7-bis/2-diethylaminoethoxy/-fluoren-9-one dihydrochloride] to ABD2F1 mice demonstrated both interferon and migration inhibitory (MIF) activity. Kinetic studies showed a close correspondence between interferon and MIF serum levels. The physiochemical characteri... | 339,871 | [
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... |
Primary structure of protein L19 from the large subunit of Escherichia coli ribosomes. | Protein L19, a component of the Escherichia coli 50S ribosomal subunit implicated in 30S-50S subunit interaction was sequenced by the dansyl-Edman method. L19 consists of a single polypeptide chain of 114 amino acids giving a calculated molecular weight of 13 002. Peptides obtained from various enzymatic cleavages were... | 339,951 | [
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[Reactions of antibodies to streptococcus group A antigens with fibroblasts of human heart interstitial connective tissue]. | The indirect immunofluorescence method was applied to the study of the serum of rabbits immunized with fractions containing nontype-specific antigens of streptococcus, group A, belonging to the cell wall proteins. Antibodies reacting with fibroblasts of the interstitial connective tissue of the human heart were reveale... | 339,973 | [
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The effect of the ionophores X-537A and A23187 on the noradrenaline output from peripheral adrenergic neurones in the presence of various divalent cations. | 1 The effects of the ionophores, X-537A and A23187 on the noradrenaline output from peripheral adrenergic neurones of isolated vas deferens of the guinea-pig were investigated in the presence of various divalent cations.2 X-537A (17 muM) caused an increase in the noradrenaline output in the presence of barium, calcium ... | 339,982 | [
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Continuous subcutaneous insulin infusion: an approach to achieving normoglycaemia. | A study was performed to examine the feasibility of achieving long periods of near-normoglycaemia in patients with diabetes mellitus by giving a continuous subcutaneous infusion of insulin solution from a miniature, battery-driven, syringe pump. Twelve insulin-dependent diabetics had their insulin pumped through a subc... | 340,000 | [
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Differential effect of D-glucose anomers on proinsulin biosynthesis by the pancreatic islets. | Pancreatic islets of Langerhans of the rat were used to study effects of D-glucose anomers on the incorporation of [3H]leucine into proinsulin and other islet proteins. At low (1 mg/ml), but not at high (2 mg/ml) glucose concentration, the alpha-anomer stimulated more proinsulin biosynthesis than the beta-anomer. This ... | 340,017 | [
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Serological reactivity in cancer patients to human and mouse fetal liver cells. | The occurrence of antibodies to human and mouse fetal liver cells has been quantitated in the sera from patients with carcinoma of breast, colon, and lung and with malignant melanoma. Also, we have demonstrated cross-reacting murine antibodies in the sera from multiparous, antifetal, and pregnant mice, which bind to mo... | 340,028 | [
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Immunohistochemical and ultrastructural identification of the pancreatic polypeptide-producing cell (PP-cell) in the human pancreas. | The consecutive semithin--thin section method was employed to identify pancreatic-polypeptide-containing cells in the human pancreas. The immunocytochemical staining of semithin sections with the peroxidase-antiperoxidase complex allowed a precise ultrastructural description of the immunoreactive cells on the adjacent ... | 340,043 | [
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[Value of the indirect immunoperoxidase reaction in the sero-diagnosis of amebiasis]. | The number of our findings is still to small to draw definite conclusions. They however show that this technique is very sensitive and highly specific for the diagnostic of tissular amebiasis. Moreover, it significantly reduces the reading difficulty, because the morphologic differences between ameba and the other elem... | 340,070 | [
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Enterotoxin antibodies in relation to diarrhoea in Swedish soldiers in Cyprus. | The development of antibodies to Escherichia coli heat-labile enterotoxin (LT) and its relationship to diarrhoea was studied in two Swedish battalions (one in the winter, WB, and one in the summer, SB) of the United Nations Peace-keeping Force in Cyprus. Whereas only 6-15% of the soldiers had detectable levels of anti-... | 340,076 | [
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Section II: General orthopaedics. Anterior cervical fusion for trauma. | Anterior bone grafts of 24 injured cervical spines were reviewed with respect to early postoperative instability and eventual malunion. Spinal redislocation or graft extrusion occurred in 21% representing failure to attain early stability. In 38%, the late complication of kyphotic malunion occurred, averaging 21%. The ... | 340,095 | [
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The classic: kyphosis dorsalis juvenilis. | Kyphosis dorsalis juvenilis, the so-called apprentice or muscular kyphosis, is caused by disturbances in the vertebral epiphyses and not as originally suggested by muscular spinal insufficiency. The pathology resembles Calvé-Perthes osteochondritis deformans juvenilis coxae and can therefore be labelled as Osteochondri... | 340,099 | [
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Drug trial in rheumatoid arthritis: a new design. | The comparative efficacy and safety of naproxen and ibuprofen were studied in 64 patients with rheumatoid arthritis. A new trial design with three aspirin periods interspersed during the study was used. By passing a smooth curve through the values obtained for the various measures of disease activity during the aspirin... | 340,113 | [
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Tinidazole and metronidazole in the treatment of intestinal amoebiasis. | Sixty adult patients with symptomatic intestinal amoebiasis and with Entamoeba histolytica present in stools were allocated at random to treatment with tinidazole or metronidazole, both administered in a dose of 2 g once daily for 3 consecutive days. The treatment period was extended in patients with stools positive fo... | 340,131 | [
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0.4152947,
0.067877... |
A comparison of an antacid plus antispasmodic combination and aluminium hydroxide in dyspepsia. | A single-blind, between-patient comparative study was carried out in general practice to assess the effectiveness of antacid plus antispasmodic combination tablets (240 mg dried aluminium hydroxide B.P., 144 mg magnesium hydroxide B.P.C., and 5 mg dicyclomine hydrochloride B.P.) and aluminium hydroxide B.P. tablets (50... | 340,140 | [
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0.3004577,
0.134587,
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... |
Measurements of cardiac output in seriously ill patients using a CO2 rebreathing method. | A CO2 rebreathing method for the measurement of cardiac output was evaluated by comparison with the direct Fick O2 method in 26 studies performed in 18 patients who were critically ill. The method requires measurement of CO2 output by collection of expired gas, of arterial PCO2, and of mixed venous PCO2 by rebreathing.... | 340,160 | [
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0.23576,
0.04883118,
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0.15897... |
The management of acute quinidine intoxication. | A 16-year-old patient survived severe intoxication with quinidine. Hypotension, rapidly progressing to oliguria and shock, was resistant to the usual therapeutic interventions but responded favorably to the use of an intra-aortic balloon pump. Some hemodynamic implications are discussed. Pulmonary edema occurred and wa... | 340,161 | [
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Affinity labelling of alcohol dehydrogenases. Chemical modification of the horse liver and the yeast enzymes with alpha-bromo-beta(5-imidazolyl)-propionic acid and 1,3-dibromoacetone. | 1. DL-alpha-Bromo-beta(5-imidazolyl)-propionic acid is a potential affinity labelling reagent for metallo-enzymes. It has been used with the alcohol dehydrogenases from liver and yeast. The liver enzyme is chemically modified and inactivated in a Michaelis-Menten-type reaction, where one molecule of the reagent is boun... | 340,220 | [
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Inhibition of chloramphenicol binding to Escherichia coli 70S ribosomes by 2'(3')-O-aminoacyl-dinucleoside phosphates derived from the aminoacyl-tRNA acceptor terminus. | The effect of 2' and 3'-O-aminoacyl-dinucleoside phosphates cytidylyl(3'-5')-2'(3')-O-L-phenyl-alanyladenosine (I), cytidylyl(3'-5')-3'-deoxy-2'-O-L-phenylalanyladenosine (IIa), cytidylyl(3'-5')-2'-deoxy-3'-O-L-phenylalanyladenosine (IIIa), cytidylyl(3'-5')-3'-deoxy-2'-O-glycyladenosine (IIb), cytidylyl(3'-5')-2'-deoxy... | 340,224 | [
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Distribution of contractile proteins and adrenergic nerves in the adrenal gland of guinea-pig, rat and ox as revealed by immunofluorescence and the glyoxylic acid technique. | Myosin and actin were localized in the adrenal gland, using antibodies against these proteins which were isolated from chicken gizzard. Myosin and actin were preferentially located in vascular walls including endothelial cells and in the capsule. In rat and guinea-pig adrenal cortex, the amount of contractile elements ... | 340,246 | [
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The effect of acutely elevated blood glucose levels on luteinizing hormone and follicle-stimulating hormone release following an intravenous gonadotropin-releasing hormone injection. | The effects of an acute blood glucose increase on the capacity of the pituitary gland to release gonadotropins (luteinzing hormone [LH] and follicle-stimulating hormone [FSH]) were studied in 21 women. Each woman received two intravenous challenges of 100 microgram of gonadotropin-releasing hormone (GNRH). Between thes... | 340,289 | [
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[The fate of people with hypertrichosis throughout history]. | Since the 16th century there are well documented examples for cases of hypertrichosis universalis. They are often confused with legends and stories of wild men. The patients were often shown at courtyards and later on at fairs. The observation of a new case of hypertrichosis universalis lanuginosa combines the descript... | 340,424 | [
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[Unusual picture of a localized argyrosis]. | Blue to black patches appeared in the scar of a sectio caesarea performed 30 years ago. Histology and electron microscopy showed a localized argyrosis due to silver suture material used in the operation. | 340,426 | [
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Formation of ribothymidine from thymine and ribonucleosides by the cell-free extract of tumors and rat tissues. | Formation of ribothymidine by the ribose exchange reaction between thymine and uridine with the cell-free extract of mouse Ehrlich ascites tumor cells was demonstrated. Since phosphate ions appear to be not required for this reaction, perhaps it proceeds by the mechnism of direct exchange of nucleoside N-ribosyltransfe... | 340,451 | [
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Colicins and bacterial membranes: structures and functions. I. Effects of colicins on the protein composition of the membranes of sensitive and tolerant Escherichia coli. | Treatment of Escherichia coli K12 C600 with colicin K or E1, but not E3, caused changes in the protein composition of the bacterial cytoplasmic membrane and an impairment of the membrane-associated ATP-linked transhydrogenase activity. The major compositional changes were loss and/or reduction in the levels of protein ... | 340,463 | [
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0.3162822,
-0.09046658... |
Recognition of right-to-left shunts following closure of low atrial septal defects. | Intraoperative dye curves are routinely employed following closure of all types of intracardiac defects. The technique has been quite helpful in a variety of problems. With atrial defects which are low in the septum or when arterial desaturation occurs immediately postoperatively, it is important that inferior vena cav... | 340,465 | [
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... |
Late results of Linton flap operation. | Linton flap operation was performed in 202 patients with postphlebitic syndrome complicated by evident ulceration 64% of patients were followed up for 1-14 years. Complete cure was obtained in 87.7%. | 340,464 | [
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0.1... |
The use of porcine xenografts on nail beds following total nail avulsion and phenol chemomatrixectomy. | The success of applying split-thickness porcine xenografts to nail beds after nail avulsion with matrix chemocauterization depends on the adherence of the graft to the underlying tissue. When this was obtained, the authors found that porcine xenografts contribute markedly toward reducing postoperative pain and drainage... | 340,498 | [
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0.07543525,
-... |
The use of a fluorescence typing method in an epidemiological study of Klebsiella infection in a London hospital. | The fluorescent antibody technique was used to investigate an epidemic of Klebsiella infection in a urological ward and to trace the probable source to a contaminated sink in the treatment room. It was also shown that cross infections by particular capsular types were very common within each ward. Certain types of Kleb... | 340,582 | [
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The sources of "OH" serotypes of Escherichia coli. | The sources from which different "OH" serotypes of Escherichia coli have been isolated are listed in a series of tables. It is considered that these tables should provide a basis for obtaining a greater understanding of the ecology of E. coli. | 340,583 | [
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Electrocardiographic mapping of the precordium in the coronary care unit. | Precordial electrocardiographic mapping systems comprising a large number of recording sites have been utilized in the Coronary Care Unit for following the natural course of ischemic injury and detecting extension of acute myocardial infarction in patients. These electrocardiographic techniques have also been found use... | 340,604 | [
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Serum protein binding and pharmacokinetics of valproate in man, dog, rat and mouse. | The serum protein binding of valproate (di-n-propylacetate) has been determined at therapeutic concentrations by equilibrium dialysis in man (94.8%), dog (78.5%), rat (63.4%) and mouse (11.9%). In dog serum, the binding was found to be independent of the valproate concentration in the range of 5 to about 70 microgram/m... | 340,640 | [
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Sporadic Legionnaires' disease. | The first case of Legionnaires' disease recognized in Pennsylvania since the Philadelphia epidemic of 1976 was that of a 53-year-old emphysematous man who had extensive unilateral pneumonia accompanied by high fever, hypoxemia, and disorientation. His illness progressed despite treatment with cephalothin, but he recove... | 340,716 | [
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[Connatal malaria (author's transl)]. | A case of connatal malaria due to Plasmodium vivax in a newborn of turkish origin is presented. Most likely the infection was acquired by materno - fetal transfusion during labor. Pathophysiological aspects and mode of transmission of this rare disease are discussed. | 340,774 | [
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[On the problem of praetherapeutic sensitivity testing of human tumours based on incorporation studies of nucleic acid precursors in vitro (author's transl)]. | Praetherapeutic sensitivity tests of human solid tumours based on incorporation studies of nucleic acid precursors have been described by various authors. This review intends to show that such tests may only be of rather limited value for the design of individual chemotherapeutic regimens. In many drugs, a correlation ... | 340,776 | [
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Immunofluorescent study of histone H5 in chick erythroid cells from developing embryos and adults. | Indirect immunofluorescence has been used to detect the presence of histone H5 in single cells during avian erythropoiesis. Evidence is presented which demonstrates that this method specifically detects histone H5. The results show that the increase in the amount of H5 which can be extracted from nuclei during erythrop... | 340,808 | [
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Erythropoiesis in the duck embryo: accumulation of H5 histone during red blood cell maturation. | We have studied the variation in histone composition of the red blood cell during embryonic development of the duck. The problem has been approached by fractionating the cells according to maturity and type in bovine serum albumin density gradients and analyzing electrophoretically histones which have been extracted fr... | 340,809 | [
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[Yeast peroxisomes, their development and operation]. | Yeast peroxisomes (microbodies) were studied, particularly with yeast methylotrophs, using light-optical microscopy, viz. intravitam phase- and anoptral-contrast microscopy, with cytochemical as well as fixed and stained objects. The data obtained were compared with cytochemical as well as fixed and stained objects. Th... | 340,851 | [
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0.00553896... |
What's new in electrosurgical instrumentation? | A 1976 report of the use of radiofrequency current to devitalize carcinomas in man stimulated this review of the historical background, the presently used techniques, and the problems associated with electrosurgery. Difficulties in electrosurgical techniques requiring further research are identified--i.e., the high hea... | 340,856 | [
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The dependence of postreplication repair on uvrB in a recF mutant of Escherichia coli K-12. | Mutants carrying recF143 or recF144 show wild type levels of host cell reactivation of UV-irradiated lambdavir and wild type rates of excision gap closure in repairing UV damage to their own DNA. The same mutants showed reduced rates of postreplication repair strand joining. When uvrA- recF- or uvrB- recF- strains are ... | 340,884 | [
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Induction of lambda prophage and of mutations to streptomycin resistance in separate small fractions of a lysogenic derivative of Escherichia coli B/r by very low doses of ultraviolet light. | The number of induced mutations to streptomycin resistance is compared at doses of ultraviolet (UV) light between 0.2 and 6.4 J/m2 in a Uvr- (excision-deficient) derivative of E. coli B/r, strain WU, and in its lambda lysogen, strain WU(lambda). At UV doses up to about 1 J/m2, which converts about 5% of the lysogenic p... | 340,890 | [
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Effects of chloramphenicol and caffeine on postreplication repair in uvr A- umuC- und uvrA- recF- strains of Escherichia coli K-12. | Postreplication repair and its inhibition by chloramphenicol and caffeine, as seen in alkaline sucrose gradients, were compared between a uv non-mutable strain uvrA- umuC- and normally mutable strains uvrA- recF- and uvrA- umu+rec+ of Escherichia coli K-12. The uvrA- umuC- strain performed postreplication repair as eff... | 340,897 | [
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Suppression of a defective alanyl-tRNA synthetase in Escherichia coli: a compensatory mutation to high alanine affinity. | Among temperature resistant revertants of a temperature sensitive E. Coli alanyl-tRNA synthetase mutant a strain was found which contains an alanyl-tRNA synthetase with an additional mutation in the structural gene of the enzyme. This mutant enzyme has a 9 or 38 fold decreased Km value for alanine compared to that of t... | 340,903 | [
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Genetic mapping of the lexC-113 mutation. | A mutation, previously designated lex-113 and suspected to be situated in the lexA locus, has been positioned by transductional studies to a unique site on the chromosome of E. coli B separate from the lexA102 and uvrA155 mutations. The order of genes in this chromosomal region was demonstrated to be malB-lexA-uvrA-lex... | 340,916 | [
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Interaction of E. coli RNA polymerase with promotors of coliphage T5: the rates of complex formation and decay and their correlation with in vitro and in vivo transcriptional activity. | The genome of virulent coliphage T5 contains about 30 sites which form stable complexes with E. coli RNA polymerase. Some of these sites bind RNA polymerase with high rates, others form extremely stable complexes as compared with promotors of other E. coli systems. The transcriptional activity of these promotors in viv... | 340,927 | [
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Chromatin. | The approximate shape of the chromatin subunit called the nucleosome is now known, but its internal architecture is not well understood. Recent studies reveal details of the organisation of DNA within the nucleosome, and show that the arginine-rich histones are essential to DNA folding. Nucleosomes or structures relate... | 340,956 | [
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A tarsal resection procedure for senile entropion with lid retraction. | 1. A method of tarso-conjunctival resection for correction of spastic entropion associated with lid retraction has been presented which prevents a) the presence of suture knots against the cornea, b) localized trichiasis, and c) tissue reaction to absorbable sutures. 2. These advantages are achieved through the use of ... | 341,017 | [
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0.3483281,
0.... |
[Comparative study of 7 cephalosporins on "Staphylococcus aureus" by the method of population analysis (author's transl)]. | Miscellaneous Staphylococcus aureus populations were tested with seven commercialized cephalosporins. The strains were divided in five groups according to the following criteria: penicillinase production or not: sensitivity to methicillin and cephalosporins; RB type resistance to methicillin; RH and RO type resistance ... | 341,049 | [
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... |
Polynucleotides. L. Synthesis and properties of poly (2'-chloro-2'-deoxyadenylic acid) and poly (2'-bromo-2'-deoxyadenylic acid). | Poly (2'-chloro-2'-deoxyadenylic acid) and poly (2'-bromo-2'-deoxyadenylic acid) were synthesized from the corresponding diphosphates with the aid of polynucleotide phosphorylase from E. coli. UV, CD, acid titration and mixing with poly (U) were investigated. Comparing these properties with those of poly (A) and poly (... | 341,084 | [
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... |
A study of the fate of pairs of cadaver kidneys. | Follow-up data collected by the EDTA Registration Committee have been linked to donor and transplant information recorded by UK Transplant by forming a 'data interface' between the two Registries. The joint data have been used to study the fate of 243 pairs of kidneys used for first cadaver grafts in 1975 and 1976. The... | 341,129 | [
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0.2305385,
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0... |
Antibodies in Escherichia coli urinary tract infection. | In 105 adults with E.Coli urinary tract infections, IgG coated bacteriuria was found in 8/9 with acute pyelonephritis (PN), 17/20 with chronic PN, and in only 2/76 with lower UTI. IgA was present in 66% of PN, but IgA secretory piece in less than 10%. These urinary IgG antibodies were, at least in part, synthesised in ... | 341,144 | [
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Survey of reviewed patients with renal transplantation. | In 110 patients 119 renal transplantations were performed from 1968 until May 1, 1975. In this survey data are given on the recipients and the transplanted kidneys. For the following papers on different complications with renal transplantation the X-ray pictures taken until May 1, 1976 were reviewed and correlated with... | 341,213 | [
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Urological complications after kidney transplantation. | The uroradiological changes and complications with 110 patients who did undergo a total of 119 renal transplantations are discussed under the following 4 topographical headings: perirenal and intrarenal, ureter including the anastomosis, bladder, urethra. In our material we found a lymphocele in 1 patient, papillary ne... | 341,214 | [
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Skeletal changes after renal transplantation. | The skeletal changes which can occur as a result of immunosuppression, and in particular as a result of hypercorticism, are discussed with reference to the findings obtained in 110 patients who received one or more kidney allografts. The hyperparathyroidism which often persists even after renal transplantation, is brie... | 341,218 | [
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... |
Human ecology in understanding environmental health problems. | The role of human ecology in understanding of environmental health problems is discussed, and the importance of study on "regional" ecosystems is emphasized in consideration of recent arguments on theoretical frame work of human ecology. After brief conceptual discussion on "regional" ecosystems, the environmental heal... | 341,240 | [
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[Physiology of the gingivo-dental sulcus]. | The gingival sulcus is formed by the space between the sulcular epithelium, the junctional epithelium, and the wall of the tooth. The functioning of its different parts is important in the early changes taking place when marginal plaque is accumulating. The cellular turnover of the junctional epithelium is very high, w... | 341,307 | [
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-0.3252844,
-0.4177053,
-0.2204502,
-0.02072144,
0.0763612,
0.5424137,
0.06525522,
0.06165012,
... |
Treatment of duodenal ulcers with cimetidine. | A total of 55 patients were treated with the histamine H2-receptor antagonist cimetidine (Tagamet: SKF) in an endoscopically controlled double-blind trial. Cimetide (200 or 300 mg every 6 hours) was administered to 36 patients, and placebo to 19 patients. Only patients who had been confirmed by endoscopy as having unco... | 341,363 | [
0.2268432,
0.2027996,
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0.3158869,
0.3232229,
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0.001129725,
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... |
Influence of HLA matching and blood transfusion on renal allograft survival. | One hundred and seven consecutive cadaver kidney transplants have been followed for up to 6 years. The beneficial effect of HLA matching, shown in previous studies, has been confirmed. The 2-year failure rate from rejection was 29% for grafts with less than two incompatibilities, in comparison with a figure of 52% wher... | 341,429 | [
-0.08586286,
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0.1555571,
0.017319,
0.3047984,
0.3585253,
0.4380302,
-0.2456352,
0.09... |
Characteristics of lymphomas in the BALB/cfRIII mouse strain. | The occurrence of 392 lymphomas in 1607 BALB/cfRIII mice from F0 to F45 is analyzed. Lymphoma incidence increased rapidly in the first 5 generations, reached a high plateau from F6 to F20 and then decreased slowly until it disappeared altogether. After F35, only sporadic cases of lymphoma have been observed. The morpho... | 341,454 | [
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0.3528425,
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... |
[The importance of herpes simplex virus type 2 (HSV-2) infection pregnancy and the period following birth (author's transl)]. | The Type 2 herpes simplex virus is mainly localized in the genital region and is transmitted by sexual intercourse. A distinction must be made between primary and recurrent infection. During pregnancy, infection of the generative tract with HSV-2 can be expected in 0.1% of cases, depending on the patient's social statu... | 341,550 | [
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0.0751778,
0.5761613,
0.2027053,
0.07630096,
0... |
Observations on the distribution of canine distemper virus in the central nervous system of dogs with demyelinating encephalitis. | The distribution of canine distemper virus in the central nervous system was examined in 11 dogs with demyelinating encephalitis by the direct fluorescent antibody technique on paraffin sections of brain and spinal cord. In the grey matter there was a good correlation between the presence and severity of lesions and pr... | 341,634 | [
0.03114607,
0.04939687,
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[Beverages of children and youth in the 16th to 19th century, documented by contemporary recollections (author's transl)]. | 227 remarks on beverages, found in biographies, personal recollections, letters a. s. o. from the 16th to the 19th century are reviewed. As early as in the children's age alcoholic drinks are represented in 27%. There is a slight trend to a reduction of alcoholic drinks in the 19th century compared with three centures ... | 341,671 | [
-0.1239789,
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0.03064357,
0.2506312,
0.03282523,
0.1273942,
0.3401695,
0.2253179,
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... |
A technique for analyzing clinical data to provide patient management guidelines. | This article describes a technique for analyzing clinical data in order to guide patient management decisions. The technique is illustrated by considering a specific decision problem encountered in the management of possible meningitis, namely, whether or not to administer antibiotics while awaiting the results of a CS... | 341,687 | [
0.01429207,
0.07963067,
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0.3253228,
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0.466198,
0.1502167,
-0.1370241,
0.0930... |
Adrenal contribution to coronary regulation in the newborn. | Evidence for adrenergic regulation of the coronary vessels was sought in 27 newborn lambs. Sympathetic activity was altered by temporarily lowering cephalic perfusion pressure (CPP) from 90 to 20 mmHg while aortic pressure was held constant. Heart rate (HR) and left ventricular dP/dt max increased markedly, while end-d... | 341,726 | [
0.1268037,
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0.25608,
0.1369539,
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0.03347293,
-0.... |
[Physiological characteristics of Salmonella typhimurium treated with penicillin]. | Growing bacteria of the two strains of Salmonella typhimurium differing in the sensitivity levels to UV-light formed multinuclear non-septal filaments in the penicillin-containing nutrient medium. The maximum number of the lifefull filaments was formed by the 4th hour of incubation in the beaf-peptone broth at a temper... | 341,800 | [
0.165964,
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0.1783683,
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0.2038686,
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0.3996676,
0.6672521,
0.25511,
0.09386304,
0... |
Bioautography: a general method for the visualization of isozymes. | A new method has been developed for visualization of isozymes which are difficult or impossible to detect with standard histochemical or autoradiographic methods. The principle of this method, bioautography, is the use of a microbial reagent to locate an enzyme after gel electrophoresis. When bioautography was compared... | 341,885 | [
0.1254335,
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0.1936768,
0.0703496,
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0.04527175,
0.3813876,
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0.4396688,
0.1657793,
0.3561012,
-0.04126393,
0.4719694,
-0.04908485,
-0.05... |
Incorporation of methionine-derived methyl groups into sirohaem by Escherichia coli. | Sirohaem is a new type of haem that has been detected as a prosthetic group of several bacterial and plant enzymes that catalyse the six-electron reductions of sulphite to sulphide or of nitrite to NH(3). When a methionine-requiring mutant of Escherichia coli K12 was grown on a minimal medium supplemented with d-glucos... | 341,886 | [
-0.3908151,
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0.2582503,
-0.2668301,
-0.006572473,
0.116262,
0.08990486,
0.4550436,
0.5457186,
-0.0929... |
House dust mite hyposensitization. | A double-blind controlled trial of house dust mite hyposensitization was carried out in 14 patients with asthma, who were hypersensitive on skin testing to the house dust mite alone. Measurements were made, using a Wright's peak flowmeter, during the 15-month trial period. Precautions were taken in the home to reduce t... | 341,952 | [
0.2197723,
0.05849807,
0.1365937,
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0.2666582,
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-0.005484654,
-0.1753088,
0.03595895,
0.125... |
Immunopathological studies on the cutaneous lesions in sarcoidosis. | We examined the immunohistology of the cutaneous granulomas in sarcoidosis. By direct immunofluorescence immunoglobulin deposits were found in the skin lesions of 5 to 8 patients. These consisted of IgM within blood vessel wall (5 patients), IgM at the epidermal-dermal junction (2 patients) and IgG within and around th... | 341,954 | [
0.1011292,
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0.1316734,
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0.04577123,
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0.3451963,
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0.2637875,
0.1354535,
0.03554635,
... |
Cimetidine: prophylaxis against upper gastrointestinal haemorrhage after renal transplantation. | The incidence of upper gastrointestinal haemorrhage within four months of renal transplantation was studied in two groups of patients. Thirty patients who received prophylactic cimetidine suffered no episodes of upper gastrointestinal haemorrhage, while six of the 33 patients who did not receive cimetidine suffered hae... | 342,062 | [
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0.07376704,
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0.3521924,
0.3947656,
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0.1165361,
0.2303488,
0.1448946,
-0.0131... |
Squamous cell carcinoma of the tongue in a nine year renal transplant survivor: a case report with a discussion of the risk of development of epithelial carcinomas in renal transplant survivors. | A case of squamous cell carcinoma of the tongue in a 26-year-old man developing nine years after renal transplantation is presented. This is the first such case to be reported. Within seven months, widespread tumor metastases resulted in death. Pathologic examination of the transplanted kidney demonstrated neither re-e... | 342,080 | [
0.02767875,
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0.257044,
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0.2773639,
0.1853411,
0.1829662,
0.08907061,
0.1580021,
0.5597509,
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0... |
Substructure of inner mitochondrial membranes of myocardial cells as shown by cryo-ultramicrotomy. | The substructure of the inner mitochondrial membranes has been studied by cryo-ultramicrotomy under conditions during which denaturation of proteins by treatment with chemical solutes has been totally avoided. In such preparations, the inner membrane has a substructure consisting of globular subunits. These subunits ha... | 342,101 | [
-0.3535688,
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0.03745599,
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0.03917577,
0.1578801,
0.2745113,
-0.1482774,
0... |
Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat. | Perfusion of rat brain followed by immersion fixation with 2.5% glutaraldehyde-1% paraformaldehyde, purification of the first antisera and application of the unlabelled antibody enzyme method were used to specifically identify vasopressin and oxytocin containing cells and fibres. The conventional sites of production of... | 342,106 | [
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0.1147,
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0.2514553,
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0.2600662,
0.1058726,
0.3355651,
-0.0685937,
-0... |
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