title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Bone ingrowth and stress shielding with a porous surface coated fracture fixation plate. | The extent of bone remodelling under metal fixation plates attached to bone by (i) normal screw fixation and (ii) bone ingrowth into a porous metallic surface underlayer sintered to the metal plate was investigated. Extensive bone remodelling was observed under the integrally bonded porous surface layered plate. This r... | 383,716 | [
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Isolation of the pericellular matrix of human fibroblast cultures. | The pericellular matrix of human fibroblast cultures was isolated, using sequential extraction with sodium deoxycholate and hypotonic buffer in the presence of protease inhibitor. The matrix attached to the growth substratum had a "sackcloth-like" structure as seen by phase contrast, immunofluorescence, and scanning el... | 383,722 | [
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Localization of an endogenous lectin in chicken liver, intestine, and pancreas. | Extracts of adult chicken liver, pancreas, and intestine contain high levels of a lectin which appears to be identical to one previously purified from embryonic chick muscle. This lectin is virtually absent from adult muscle, but is highly concentrated in cells lining liver sinusoids, intestinal goblet cells, and the e... | 383,728 | [
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A morphological study of the interaction between Trypanosoma cruzi and rat eosinophils, neutrophils and macrophages in vitro. | The interaction between trypomastigotes of T. cruzi and purified rat eosinophils, neutrophils and macrophages has been studied. Macrophages induced by dextran, became infected and the parasites multiplied as amastigotes, eventually being released as trypomastigotes into the medium. Eosinophils show an antibody-dependen... | 383,733 | [
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Effect of LRH on gonadotropin secretion in newborn male infants. | The concentrations of LH and FSH were measured in eight male newborn babies, aged 4-6 h, before and after the administration of 25 micrograms synthetic LHR. A comparison was performed with six control newborns receiving normal saline. Both LH and FSH rose significantly in all subjects after LHR administration. Their va... | 383,738 | [
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Considerations for establishing the validity of immunocytological studies. | Immunocytology has wide spread applications for localizing tissue antigens, as evidenced by the recent exploitation of this technique in biological studies. Documenting the immunological specificity of the staining reaction is one of the most important technical considerations in validating the accrued data in immunocy... | 383,826 | [
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Identification of immunoreactive sites in bovine parathyroid cells to antibodies raised against the NH2-terminal sequence of parathyroid hormone. | The NH2-terminal sequence of bovine parathyroid hormone (1-84) was localized with different immunocytochemical methods on the light and electron microscopic level in bovine parathyroid glands and in isolated bovine parathyroid parenchymal cells. The peroxidase labeled staphylococcal protein A and the peroxidase anti-pe... | 383,828 | [
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An alternative method of expressing results of lymphocyte transformation experiments. | The use of counts per minute, disintegrations per minute and stimulated index as a means of expressing lymphocyte transformation is discussed. An alternative method is proposed, namely, that the degree of transformation is more effectively measured by the difference in incorporation of nucleoprotein base by stimulated ... | 383,845 | [
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In vitro induction of cytotoxic effector cells against human neoplasms. I. Sensitization conditions and effect of cryopreservation on the induction and expression of cytotoxic responses to allogeneic leukemia cells. | Peripheral blood lymphocytes (PBL) from normal human donors were sensitized in vitro against allogeneic human acute myelocytic leukemia (AML) cells by means of an unidirectional mixed lymphocyte-tumor cell culture (MLTC) technique. The cytotoxic responsiveness of the sensitized lymphocytes, as determined in vitro by th... | 383,844 | [
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[Artificial endocrine pancreas (author's transl)]. | 16 years ago Kadish (1963) Trans. Amer. Soc. Artif. Org. 9, 363--367) published his first pioneering experiments with an extracorporal blood glucose regulating machine. These experiments were fundamental to the development of an artificial endocrine pancreas that replaces the natural regulator of the blood glucose. Eno... | 383,880 | [
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High and low toxin production by a non-toxigenic strain of Clostridium botulinum type C following infection with type C phages of different passage history. | Toxin production in Clostridium botulinum types C and D is governed by specific bacteriophages. Prior passages of a phage controlling type C toxin production caused subsequently lysogenized bacteria to become variably toxigenic. This appears to be one of the causes of the decrease in toxigenicity which is common in som... | 383,896 | [
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Salmonella phage glycanases: substrate specificity of the phage P22 endo-rhamnosidase. | Interaction between phage P22 and phenol-water extracted lipopolysaccharides from sensitive Salmonella bacteria belonging to serogroups A, B and Di results in hydrolysis of the alpha-L-rhamnosyl linkages within the tetrasaccharide repeating unit of the O-antigenic polysaccharide chain. These O-antigens have identical s... | 383,902 | [
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Cellular survival of human marrow during placement of marrow-cancellous bone grafts. | The survival of human marrow cells during the placement of marrow-cancellous bone grafts was studied by three independent viability assays. Marrow cells are resistant cells able to survive the surgical harvest from the ilium. Salt solutions such as normal saline solution and 5% dextrose in water (D5W) were superior to ... | 383,921 | [
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Tissue response to posterior denture base-type pontics. | Several factors have been presented that must be evaluated when selecting an appropriate posterior pontic design. Because of the controversy that exists with regard to using posterior denture base pontics, a long-span fixed partial denture was followed for 14 months. Results indicate that tissue health can be maintaine... | 383,958 | [
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Simplified method for removing intraradicular posts. | A technique for post removal prior to endodontic or restorative retreatment procedures has been presented. This simplified procedure is not only highly efficient, but also reduces or eliminates risks encountered in other treatment modalities. | 383,968 | [
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Effect of suppression of plasma prolactin on ovulation, plasma gonadotrophins and corpus luteum function in LH-RH-treated anoestrous ewes. | Nineteen Scottish Blackface ewes were given LH-RH (3 X 30 micrograms i.v., 90-min intervals) during anoestrus when prolactin levels were elevated. Plasma levels of prolactin were suppressed with CB 154 (twice daily, i.m.) on Days -5 to 0 (N = 5), 0 to +5 (N = 5) or -5 to +5 (N = 5) around the day of LH-RH treatment (Da... | 383,978 | [
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Concentration-dependent mutation by alkylating agents in human lymphoblasts and Salmonella typhimurium: N-methyl-N-nitrosourethane and beta-propiolactone. | The toxic and mutagenic effects of the alkylating agents N-methyl-N-nitrosourethane (MNUT) and beta-propiolactone (BPL) were quantitatively measured in human lymphoblasts and Salmonella typhimurium. Forward mutation to 6-thioguanine resistance was measured in the human lymphoblasts, and forward mutation to 8-azaguanine... | 384,009 | [
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Antimicrobial resistant Salmonella spp. isolated from double-crested cormorants (Phalacrocorax auritus) and common loons (Gavia immer) in Florida. | Antimicrobial resistant Salmonella spp. were found in double-crested cormorants and common loons in Florida. Single or multiple resistance occurred in all Salmonella agona isolates from cormorants, primarily to ampicillin, sulfonamids, streptomycin, neomycin, and kanamycin. Similar patterns of resistance were found in ... | 384,026 | [
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[Netherton-Comel's syndrome]. | Two cases of the so-called Netherton's syndrome are described and the relevant literature is reviewed. On the author's opinion there exists no relationship between the disease and ichthyosiform dermatoses. It fits more adequately in the group of the "Génodermatoses érythémato-desquamatives circinées variables" of Bazex... | 384,113 | [
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[Immunothermistor unit]. | An immunotermistor has been devised for studying immunological reactions. It includes a probe pack, a measuring pack and an automatic potentiometer. The adoption of analogue integral microcircuits enabled the authors to make a unit with high reliability, small size and mass. The error in assessing immunological reactio... | 384,137 | [
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Studies of colicin induction with an imm- col+ mutant of the plasmid colicin E1. | A mutant of a derivative of the colicin E1 plasmid has been isolated that does not confer immunity to colicin E1 on its host (imm-) although it is still capable of producing colicin (col+). Cells carrying the col+, imm- plasmid are capable of forming colonies and grow best in liquid culture in the presence of trypsin. ... | 384,154 | [
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Tandem and inverted repeats of arginine genes in Escherichia coli: structural and evolutionary considerations. | Duplications of arg genes produced in the Rec+ and in the recA genetic backgrounds are shown by heteroduplex analysis to be strictly tandem at the level of resolution of this technique. The formation of these particular rearrangements therefore does not require the inclusion of transposons or other sequences of an appr... | 384,163 | [
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Structure of the malB region in Escherichia coli K12. II. Genetic map of the malE,F,G operon. | Starting with a strain containing a malK-lacZ fusion, a series of lambda plaque-forming phages which carry varying amounts of the malE,F operon have been isolated. We have used these phages to construct a deletion map of the malE,F operon. The construction of this deletion map has led to the identification of a new gen... | 384,167 | [
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Repair promoted by plasmid pKM101 is different from SOS repair. | In E. coli K12 bacteria carrying plasmid pKM101, prophage lambda was induced at UV doses higher than in plasmid-less parental bacteria. UV-induced reactivation per se was less effective. Bacteria with pKM101 showed no alteration in their division cycle. Plasmid pKM101 coded for a constitutive error-prone repair differe... | 384,220 | [
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Mutagens in the feces of 3 South-African populations at different levels of risk for colon cancer. | The incidence of mutagens in the feces of 3 South-African populations at different risk levels for colon cancer has been determined. Lyophilized fecal samples were extracted with ether and the mutagenicity of the extracts determined using the Salmonella/mammalian microsome mutagenicity test. 19% of the samples from urb... | 384,227 | [
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Failure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer. A controlled trial. | One hundred and fifty patients with advanced cancer participated in a controlled double-blind study to evaluate the effects of high-dose vitamin C on symptoms and survival. Patients were divided randomly into a group that received vitamin C (10 g per day) and one that received a comparably flavored lactose placebo. Six... | 384,241 | [
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Clinical genetics and pediatric neoplasms: pathogenetic and etiologic perspectives. | Clinical and genetic aspects of pediatric neoplasms were reviewed from pathogenetic and etiologic perspectives. Developmental principles and phenomena common to several tumors and tumor syndromes were identified, summarized, and critically evaluated. Their enumeration may be useful in future cancer research. No single ... | 384,265 | [
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Fetal cardiac arrhythmias. | Fetal cardiac arrhythmias have been classified and the current literature reviewed. Emphasis is placed on antepartum diagnosis and appropriate therapy. The incidence of congenital heart disease varies with the type of arrhythmia. The differential diagnosis of fetal cardiac arrhythmias and management are discussed. | 384,305 | [
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0.01380233,
0.09081632,
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0.05830833,
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Electron microscopy of adipose tissue tumors: comparative features of hibernomas, myxoid and pleomorphic liposarcomas. | Two hibernomas, 16 myxoid, and eight pleomorphic liposarcomas were studied by transmission electron microscopy. Neoplastic cells in hibernomas and the type I cells--adipocytes--in myxoid liposarcomas consistently display abundant lipid droplet populations and prominent basal lamina deposition. Despite some variability ... | 384,339 | [
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Nucleotide sequence of the mitochondrial structural genes for cysteine-tRNA and histidine-tRNA of yeast. | We have determined the nucleotide sequence of a segment of Saccharomyces cerevisiae mtDNA that contains the structural genes for a cysteine-tRNA and a histidine-tRNA. The genes are approximately 85 bp apart, they do not contain intervening sequences or sequences coding for the 3'-CCA terminus and they are surrounded by... | 384,365 | [
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A transpositional skin flap for release of volar contractures of a finger at the MP joint. | We describe a finger flap which, in properly selected patients, and with careful planning of the incision design, has been useful for covering small defects over the volar aspects of the MP joint. The donor site can be closed without skin grafting. | 384,434 | [
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Moral treatment reconsidered: some sociological comments on an episode in the history of British psychiatry. | A reappraisal is offered of the precise sense in which the introduction of moral treatment at the end of the eighteenth century marked a decisive shift in our characteristic ways of responding to and coping with the mentally disturbed. Some connections are explored between this new approach to the 'mad' and larger soci... | 384,444 | [
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Effects of relaxation therapy on cardiac performance and sympathetic activity in patients with organic heart disease. | Six patients, with surgically implanted tantalum myocardial markers, were trained in deep muscle relaxation therapy. Analysis of individual responses and group means of blood pressure and ventricular dimensions during relaxation showed a decrease in plasma norepinephrine levels and indices of myocardial contractility c... | 384,447 | [
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Psychopathology and psychotherapy in chronic physically ill patients. | Within the scope of psychosomatic medicine somato-psychic diseases are of great importance theoretically as well as practically, especially in view of problems dealing with the patient's attitude toward his illness and his coping with the disease. Among the somato-psychic illnesses chronic physical diseases are of prim... | 384,449 | [
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Materialism and spiritualism: the dualistic way of Western thinking. | Ever since the beginning of Western philosophy in ancient Greece there have been two fundamental approaches to life in general: materialism and spiritualism. In the Renaissance this basic question came into discussion again. In the 19th century the real fight began. On the one hand we have had the materialistic 'leftis... | 384,451 | [
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Spontaneous argyrophil cell carcinoid in the glandular stomach: immunohistochemical study of gastric endocrine cells in normal and tumour-bearing mastomys. | Endocrine tumours (argyrophil cell carcinoids) are frequent in the oxyntic mucosa of mastomys. The tumour is notable for its high histamine content and for its high histidine decarboxylase activity. The tumour is thought to arise from the histamine-storing, enterochromaffin-like cells of the oxyntic mucosa. They are of... | 384,503 | [
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[Stimulation for a "personal history of behavior modification" as well as further thoughts]. | The intention of this article is not to make a contribution to the historical analysis of the complex structure of conditions which eventually led to the development of the many techniques of Behavior Modification. Due to the increasing interests -- especially recently -- for the real and true fathers, grand-fathers an... | 384,694 | [
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[Investigation on the presence of salmonella in drinking water from water supplies and distribution systems in Togo (author's transl)]. | Bacteriological drinking water examination of samples from water works and wells as well as from their distribution systems revealed that from 26 samples, where Salmonella organisms could be isolated, in 16 cases E. coli- and coliforms could not be found and that in 9 of these cases even the colony count was below 100 ... | 384,726 | [
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Scanning electron microscopy of epiplexus macrophages responding to challenge by bacillus Calmette-Guerin. | The present investigation examined the morphological characteristics of epiplexus macrophages following a single intracisternal injection of the antigen, bacillus Calmette-Guerin (BCG). Three days following injection of BCG (0.5 - 4.0 X 10(8) viable microorganisms), mongrel dogs were perfused with buffered aldehydes. T... | 384,740 | [
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Complications of cerclage. | The published results of cervical cerclage are almost invariably good and there is little mention of complications. Forty per cent of 52 pregnancies, with 38 early "prophylactic" and 14 late "therapeutic" operations, ended after 260 days' gestation. In 73 per cent a viable infant was born. The most frequent complicatio... | 384,742 | [
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[The anodically moving thermolabile antigen (ATA) of Gram negative bacteria. Protection of mice by immunization with ATA (author's transl)]. | Mice are protected against lethal doses of Salmonella typhi-murium by vaccination with ATA extracted from Providencia. No protective effect is observed when the S. typhi-murium strains are enterotoxigenic. Thus protection is antibacterial, but not antitoxic. | 384,750 | [
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The magazine picture collage: its clinical use and validity as an assessment device. | To contribute to an understanding of the magazine picture collage as a clinical assessment device, experienced psychiatric staff from various disciplines were asked to distinguish the collages of hospitalized psychiatric patients from those of paired controls, to note whatever descriptive and dynamic features about the... | 384,776 | [
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Myelomatous pleural effusion: clinical course and immunologic characterization of the pleural fluid cells. | Multiple myeloma is a disease that infrequently involves nonreticuloendothelial tissues and rarely causes pleural effusion. A 59-year-old woman had pleural effusion as the major manifestation of multiple myeloma. Light microscopy of her pleural fluid with Wright stained preparations showed all cells to be bizarre and o... | 384,784 | [
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Experimental fibrogenesis: enhancement by chronic ethanol administration. | The authors have presented a new, simple, and reproducible model of fibrogenesis and have shown that chronic alcohol treatment clearly stimulates the production of fibrous tissue in this model. | 384,829 | [
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Congenital diaphragmatic hernia. | A description of the pathology, clinical presentation and management of congenital diaphragmatic hernia is given together with the results obtained in Newcastle during the last seven years. Some suggestions are made for improved management. | 384,841 | [
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Recurrent urinary tract infections in men. Characteristics and response to therapy. | All men with recurrent urinary tract infections entered into a study had a positive antibody-coated bacteria test, and 52% had evidence for prostate infection. Escherichia coli infection was present in 74% and urinary tract symptoms in 57% of those randomized. Thirty-eight patients were randomized in a double-blind cli... | 384,858 | [
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The muscle content and contractile capability of the common bile duct. | The supraduodenal portion of the human and canine common bile duct has been shown by indirect immunofluorescent staining with anti-actin sera to contain scattered bundles of smooth muscle arranged predominantly in a longitudinal direction with respect to the axis of the bile duct. Isolated strips of canine common bile ... | 384,884 | [
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Comparison of EC broth and medium A-1 for the recovery of Escherichia coli from frozen shucked snow crab. | Two variations of the multiple-tube fermentation technique were used to enumerate fecal coliforms in commercially processed, frozen crab meat. These were the EC confirmation test and a more rapid method that requires medium A-1. The method with medium A-1 was more specific than the EC confirmation test for detecting Es... | 384,899 | [
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Enzyme-linked immunosorbent assay for detection of Clostridium botulinum type E toxin. | The enzyme-linked immunosorbent assay using the "double-sandwich" technique was utilized to determine Clostridium botulinum type E toxin. With this technique, about 80 mouse intraperitoneal 50% lethal doses of toxin could be detected. Cross-reaction was hardly observed with C. botulinum type A and B toxins. No cross-re... | 384,908 | [
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Thoracic duct fistula and renal transplantation. | Thoracic duct drainage (TDD) was established for 21-115 days in 40 kidney recipients with an average removal per patient day of 4.7 1 lymph and 1.88 billion cells. Cellular and humoral immunity were depressed. TDD and immunosuppressive drugs were started at transplantation in 35 recipients of cross-match negative graft... | 384,943 | [
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Alimentary tract complications after renal transplantation. | A computer analysis of post renal transplantation gastrointestinal problems was performed to identify important associated clinical factors. Thirty-seven per cent of all transplant recipients developed one or more significant problems. Hemorrhage, nondiverticular intestinal perforation, and esophagitis occurred most fr... | 384,945 | [
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Relaxed mutants of Serratia marcescens SM-6. Biochemical traits and relevance of the rel+ allele for the formation of exoenzymes. | Serratia marcescens SM-6 when starved for a required amino acid stops synthesizing protein and RNA and accumulates two nucleotides which co-chromatograph with ppGpp and pppGpp. These features are characteristic of bacterial strains with stringent RNA control (rel+). Two independent mutants were isolated which resemble ... | 384,954 | [
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Exploratory psychotherapy in the treatment of psoriasis. Twelve hundred years ago. | Twelve hundred years ago, Jasaliq, a Persian physician, treated a patient who was suffering from psoriasis. Although psoriasis was not clearly differentiated from leprosy in the West until the 1840s, it was clinically described and differentiated as a separate entity in Persia in the eighth century AD. In this case his... | 384,957 | [
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Electron-dense subepithelial glomerular deposits in Henoch-Schönlein purpura syndrome. | A case of Henoch-Schönlein purpura (HSP) with renal lesions is presented. The clinical, laboratory, and morphologic findings revealed features commonly described in HSP. A renal biopsy revealed diffuse, generalized, proliferative glomerulonephritis. The unusual findings in this case were numerous electron-dense subepit... | 384,959 | [
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Primary excision and grafting of burns located over an open fracture. | Early excision of the burn, immediate autografting, reduction of the fracture, and stabilization with a plaster-of-paris cast is offered as an alternative method for managing burns with associated long-bone fractures. The opportunity to excise and immediately autograft a burn wound requires rethinking of the entire pro... | 384,962 | [
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A clinical and laboratory evaluation of a polyurethane foam: a new donor site dressing. | A polyurethane foam (Lyofoam) has been reported to accelerate epithelization of a wound. The purpose of this study was to evaluate its efficacy as a donor-site dressing for thermally injured patients. Thus, partial-thickness injuries were made in ten pigs and covered with Lyofoam, Xeroform, Telfa, Scarlet Red, and fine... | 384,963 | [
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0.1335496,
0.133957,
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0.1... |
Meiges disease: a clinical form of facial convulsion, bilateral and medial. | In 1910 the French neurologist Henry Meige described in detail a disorder characterized chiefly by symmetric dystonic spasms of the facial muscles, which he called "spasm facial median." Cases with this disorder are rare, and frequently misdiagnosed and inappropriately treated. We report here a translation of Meige's o... | 384,981 | [
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Interferometric visual acuity testing in anterior segment disease. | Preoperative and posteroperative visual acuities for Landolt ring targets and for a grating target of comparable retinal illuminance produced by two-beam interference were assessed in patients with anterior segment disease. Good preoperative interferometric acuities (6/12 or better) were found in over half of the cases... | 384,983 | [
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Quaternary structure of DNA-dependent RNA polymerase from Escherichia coli. Measurement of distances by fluorescence energy transfer. | Distances between the subunits in Escherichia coli RNA polymerase (core and holo enzyme) and the rifamycin binding site have been determined using the nonradiative energy transfer technique. The appropriate donor and acceptor labels have been chosen in order to optimize the spectral overlap and maximize the energy tran... | 385,059 | [
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Library school education for medical librarianship. | This paper reviews the current situation in library school education for medical librarianship in the United States and Canada based on information from a questionnaire sent to teachers of courses in medical librarianship in accredited library schools. Since 1939, when the first course devoted entirely to medical libra... | 385,086 | [
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Assessment of patients for psychotherapy. | Factors in the patient which have been commonly cited by therapists as relevant in assessment for psychotherapy are examined as well as the research done on them. These factors are discussed under four categories: (a) factors related to the illness, (b) personal factors related to the treatment, (c) personal factors no... | 385,092 | [
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Basal forebrain facilitation of reflex swallowing in the cat. | In adult cats anaesthetized with urethane, electrical and chemical stimulation of the basal forebrain facilitated reflex swallowing elicited by electrical stimulation of the superior laryngeal nerve. A systematic stereotaxic mapping study using electrical stimulation revealed that the facilitatory sites were distribute... | 385,108 | [
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Sets of neurons in somatic cerebral cortex of the cat and their ontogeny. | The process of set formation is briefly reviewed and five monothetic schemes for classification of neurons in the somatic cerebral cortex are described. Criteria for evaluation of neuronal sets are presented and applied to the five different monothetic classification schemes. Classification by size and distribution of ... | 385,112 | [
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Bacterial filters - are they necessary on anaesthetic machines? | At the Vancouver General Hospital the effectiveness of the system for decontamination of anaesthetic equipment was evaluated to determine the need for bacterial filters on anaesthetic machines. Two groups of patients were studied. Group I consisted of 33 patients, none of whom had clinical symptoms of respiratory tract... | 385,119 | [
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Studies on experimental enteric salmonellosis in ponies. | Clinical, bacteriological, serological and haematological observations were made on 13 adult ponies orally inoculated with Salmonella typhimurium. The results were compared to two control ponies and four others infected by accidental transmission. The clinical responses in inoculated ponies included pyrexia lasting fou... | 385,122 | [
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Evaluation of in vitro incubation systems for the study of gonadotropin release. | A detailed study was undertaken in order to determine if a pituitary-half incubation system were a suitable model for the study of anterior pituitary response to estradiol and LHRH. Considerable variation in the gonadotropin content of randomized pituitary halves was observed. Much less variation was found in matched h... | 385,298 | [
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50-S subunit from Escherichia coli ribosomes. Isolation of active ribosomal proteins and protein complexes. | A method is described for the isolation of highly purified proteins from the 50-S subunit of Escherichia coli ribosomes. All the proteins from the large subunit could be isolated with the exception of L14, L26, L31 and L34. The isolated proteins are functionally active in reconstituted particles. The method consists of... | 385,308 | [
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Irreversible inactivation of pyruvate decarboxylase in the presence of substrate and an oxidant. An example of paracatalytic enzyme inactivation. | Pyruvate decarboxylase from yeast is progressively inactivated in the presence of pyruvate and an extrinsic oxidant such as 2,6-dichloroindophenol or hexacyanoferrate(III). The inactivation is linked to the oxidation of the hydroxyethylthiamine diphosphate intermediate to acetate. Removal of low-molecular compounds by ... | 385,313 | [
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Protein . nucleic-acid reaction kinetics. Theoretical analysis of the binding reaction between DNA and RNA polymerase. | This paper presents methods developed in order to analyze experimental results concerning the binding of Escherichia coli DNA-dependent RNA polymerase to DNA at high and at low DNA concentrations, using the filter retention assay. The basis hypotheses, under which the mathematical expressions for describing the kinetic... | 385,315 | [
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Reconstitution of active 30-S ribosomal subunits in vitro using heat-denatured 16-S rRNA. | 30-S ribosomal subunits which have been reconstituted using heat-denatured 16-S rRNA can participate in the synthesis of lysosyme in vitro. Therefore all the information contributed by 16-S rRNA to the reconstitution process is carried in the primary sequence of this RNA. The specific protein-synthesizing activity of 3... | 385,316 | [
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Iron supply of Escherichia coli with polymer-bound ferricrocin. | Uptake of ferric iron from ferricrocin was studied in Escherichia coli using a polymer-coupled ferricrocin that was unable to penetrate into the cell. Ferricrocinyl polyethylene glycol succinate (Mr 7000 -- 8500) promoted growth of E. coli K-12 AB2847 aroB under iron-limiting conditions. In iron-starved cells, uptake o... | 385,320 | [
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Effect of D-leucine-6-luteinizing hormone-releasing hormone ethylamide in patients with hypogonadotropic hypogonadism with anosmia. | Four men with hypogonadotropic hypogonadism and anosmia were tested with acute intravenous injections of luteinizing hormone-releasing hormone (LH-RH) and D-leucine-6-LH-RH-ethylamide (D-L eu-6-LH-RH-EA) with a 1-week interval. Each patient was then treated with this drug for 60 days and tested again after this period ... | 385,362 | [
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A controlled comparative trial of mianserin and diazepam in the treatment of anxiety states in psychiatric out-patients. | Forty psychiatric out-patients with primary anxiety entered a double-blind trial comparing 2 weeks of treatment with mianserin 30--60 mg daily or diazepam 15--30 mg daily, followed by 2 weeks of single-blind placebo administration. Both drugs were effective anti-anxiety agents, but mianserin was significantly superior ... | 385,399 | [
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Effect of 2-deoxyglucose on [32P] phosphate and insulin release from perifused rat pancreatic islets. | The effect of 2-deoxyglucose on glucose mediated insulin and [32P]phosphate release was studied by perifusion of isolated rat pancreatic islets. When islets were perifused with media containing 2.8 mmol/l glucose and 20 mmol/l 2-deoxyglucose for 60 minutes and then exposed to media containing 8.3 or 16.7 mmol/l glucose... | 385,404 | [
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Immunogenicity of a killed E. coli 0111:K58 vaccine administered orally to children. | A killed E. coli 0111:K58 vaccine was administered by the oral route to 16 children ranging from 3 months to 7 years of age. The antibody response was measured at different times after the vaccination through the titration of agglutinating antibodies in serum and in fecal extracts, and the detection of specific IgA imm... | 385,407 | [
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[Protective action of colicinogenic factor Ib-P9 on Escherichia coli cells defective in known repair functions after ultraviolet irradiation]. | The presence of the plasmid colicinogenic factor Ib-P9 in Escherichia coli wild type cells is shown to increase bacterial survival after UV irradiation and the action of N-methyl-N'-nitro-N-nitrosoguanidine. The ability of the plasmid to cause the UV protection is observed in uvrA, uvrB, uvrC, polA, recB, recF E. coli ... | 385,450 | [
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Double-blind controlled trial of cimetidine in the healing of gastric ulcer. | Sixty patients with gastric ulcers were treated for four weeks with either 1 g cimetidine per day or with identical tablets containing lactose. The healing rate, assessed by endoscopy, was 23 out of 35 (66%) in the patients given cimetidine and 13 out of 25 (52%) in those given placebo. The difference between the group... | 385,458 | [
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Effect of estrogen and testosterone on the gastric secretion of rats and conscious rabbits. | Shay rats and conscious rabbits were used to study the effect of sex hormones on gastric secretion. Daily injections of estradiol-di propionate and testosterone-propionate were given separately to each set of animals, while the control animals received solvent alone for the same duration of time. Estrogen inhibited gas... | 385,496 | [
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C. parvum treatment of transplanted rat tumours of spontaneous origin. | C. parvum (Wellcome CN6134) has been examined for suppression of a range of transplanted rat tumours of spontaneous origin. With five tumours (three mammary carcinomas and two fibrosarcomas) growth of comparatively high cell inocula (with respect to the minimum for growth in control rats) was suppressed by admixture wi... | 385,514 | [
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Psychiatric presentation of Jakob-Creutzfeldt disease. | A case of presenile dementia, which on a post-mortem examination proved to be due to Jakob-Creutzfeldt Disease, is described. The most dramatic early clinical feature was that of hysterical aphonia, temporarily removable by hypnotic suggestion. Anxiety symptoms and irritability also occurred early on, followed by a tra... | 385,584 | [
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Membrane receptors for aspartate and serine in bacterial chemotaxis. | High affinity binding sites for serine and aspartate have been characterized in membranes from Salmonella typhimurium and Escherichia coli. Greater than 80% of these sites have been identified as chemotaxis receptors. Mutants lacking binding sites for these amino acids have been shown to have corresponding defects in t... | 385,590 | [
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[Original removing technique of the kidneys for transplantation. An experimental study (author's transl)]. | The depicted procedure minimizes the hazards of aggressive manipulations, and excludes any possibility of so-called "warm ischaemia". The kidneys are flushed out in situ with cool pulsatile perfusion through an aortic cannula. Kidneys, aorta and inferior vena cava are then removed en-bloc without interrupting the perfu... | 385,608 | [
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Quantitative assay of soluble beta-hemolytic streptococcal antigens via an immunochemical turbidimetric method with a spectrophotometer. | Soluble, group A, B, C, and G beta-hemolytic streptococcal antigens were successfully identified in a prototype spectrophotometric system by an immunochemical turbidimetric assay. Any spectrophotometic system which can take a zero reading followed by a second reading 2 or more min later can be used for the assay. Maxim... | 385,619 | [
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Evaluation of the new API 20C strip for yeast identification against a conventional method. | The new API 20C yeast identification system together with appropriate microscopic morphology determinations achieved a 97% correlation with a rapid conventional method. Whereas a group composed of Candida, Torulopsis, Saccharomyces, and Rhodotorula was identified with ease (98% overall correlation), a second group, con... | 385,621 | [
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0.1295489,
-0.1485679,
-0.01225964,
-0.2187421,
-0.334022,
0.1563713,
-0.5154075,
-0.1415715,
-0.3068228,
0.305627,
-0.1318845,
-0.2336957,
0.3773736,
0.6027386,
0.22514,
0.2735... |
[Keratoplasty. Urgent treatment of the corneal perforation (author's transl)]. | Sixteen keratoplasties (15 perforating, 1 lamellar) were performed on 12 perforated corneas and on 2 eyes threatened by imminent corneal perforation. The causal disease was metaherpetic kératitis (6 cases), chronic and recurrent ulcers (4 cases), acute keratoconus (1 case) and corneal traumas (3 cases). Enucleation has... | 385,700 | [
-0.1677026,
-0.2627032,
-0.2259279,
0.1311301,
0.1778301,
-0.3917148,
-0.4010293,
-0.2104161,
0.4823699,
0.09608346,
0.07729947,
-0.1892269,
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0.04704218,
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-0.2589296,
0.0544393,
-0.2381086,
0.03430507,
0.1440408,
-0.1194782,
0.004148007,
... |
Combined orthodontic-periodontal treatment of an infrabony defect. A case report. | A case presentation involving the combined orthodontic-periodontic treatment of a distally inclined mandibular left central incisor with a mesial infrabony defect is reported. Treatment was performed in three phases: (a) the tooth was moved upright (b) periodontal surgery with osseous grafting of the infrabony defect w... | 385,827 | [
-0.3040247,
0.3288133,
-0.05729659,
-0.04905341,
0.1263196,
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0.03070136,
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0.1383445,
0.06345861,
0.08397309,
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0.03217389,
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-0.3929018,
0.02573597,
-0.628408,
-0.224916,
0.02412676,
0.1858321,
0.1791375,
... |
The grinding efficiency of diamond burs. | Deterioration of round diamond burs during 8 minutes of operation was found to be more pronounced for burs with low particle densities than for burs with high particle density. No definitive relationship was found between the initial grinding rate and initial particle density. | 385,844 | [
-0.06753314,
0.3398197,
-0.009357965,
-0.1983372,
0.1285801,
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0.1736168,
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0.03889432,
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0.19504,
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0.1603144,
-0.2032384,
0.106218,
0.1952084,
0.1222672,
... |
Relationship of the incisive papilla to the maxillary central incisors. | The average distance between the most anterior point of the maxillary central incisors and the most posterior point of the incisive papilla was 12.454 mm with a standard deviation of 3.867 mm. This distance was measured when these two points were projected on a plane which was parallel to the reference plane formed by ... | 385,848 | [
-0.1671148,
0.1523612,
-0.05312538,
-0.09894366,
0.2855888,
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-0.1262739,
0.2006437,
0.2547349,
0.281321,
0.153262,
-0.03228442,
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-0.009994742,
-0.1653381,
-0.3090645,
-0.4007943,
0.0970428,
-0.4247355,
-0.2329571,
0.233585,
0.1190711,
0.2335119,
-0... |
Comparison of the retentive strength of two cast gold pin techniques. | The retention contributed by the use of pins with gold castings can be substantially increased by the technique of placing a threaded pin in the dentin and making a casting with a threaded receptacle to fit the pin. The basis for the improvement is the greater retention of threaded pins to dentin compared to that of sm... | 385,851 | [
0.1735687,
0.4151966,
-0.08119991,
-0.1551457,
-0.2942594,
-0.3968003,
-0.04410281,
0.0178727,
0.02905569,
0.5691491,
0.0190066,
0.1783038,
-0.09158774,
0.0077441,
-0.4879015,
-0.4946309,
-0.08889252,
-0.2766668,
-0.05797118,
-0.3254013,
0.001415241,
0.008302478,
0.076445... |
A simplified approach to the complete porcelain margin. | The technique described produces a metal-ceramic crown exhibiting excellent esthetic qualities and marginal accuracy superior to that achieved on the cast metal margin. A platinum foil apron or refractory dies are not necessary. A precise shoulder preparation, preferably with two master dies, is required. A chamfer wit... | 385,853 | [
-0.03029862,
0.5073122,
0.1468263,
0.02378034,
-0.1720888,
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0.1515293,
0.07480647,
0.4108483,
0.2391215,
0.02269582,
-0.321438,
0.1719994,
-0.2008196,
-0.2230208,
-0.170638,
-0.2075103,
-0.2049025,
-0.2859389,
0.06134062,
0.3506367,
-0.09571686,
0.2288687,
0... |
[Antibiotic treatment of pneumococcal meningitis (author's transl)]. | Pneumococcal meningitis, which represents the third in frequency among the purulent forms of meningitis, continues to be, in spite of antibiotic therapy, a serious problem due to its high mortality rate, which reaches 50 per cent in patients of advanced age. The antibiotic treatment of choice is penicillin G, using chl... | 386,009 | [
-0.03187657,
-0.1445898,
0.07518078,
-0.02748137,
-0.2055273,
-0.076252,
-0.2901998,
-0.245731,
-0.1001625,
-0.090591,
0.07596385,
0.2047906,
-0.299408,
0.2147844,
-0.3338958,
-0.1719876,
-0.0209045,
0.1688053,
-0.2193342,
0.3473161,
0.516119,
-0.3146665,
0.05583347,
-0... |
An interactive computer program to teach and investigate diagnostic processing. | An interactive computer program designed to present information about a patient taken from a history, physical examination and investigations is described. The application and advantages of the technique for the purposes of teaching and investigating medical (diagnostic) problem-solving are briefly discussed. | 386,011 | [
-0.2594335,
0.01963746,
-0.1934003,
0.04689113,
0.1595973,
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-0.262693,
-0.1939932,
0.1513801,
-0.06174316,
0.1325129,
0.1091325,
0.004045349,
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0.07660985,
-0.2808214,
0.0004928045,
-0.3090291,
0.3076267,
0.224728,
-0.1011851,
-0.1181313,
... |
Post-translational modification of Escherichia coli ribosomal protein S6. | Escherichia coli has multiple forms of ribosomal protein S6, differing in number of glutamyl resideus at the C-terminal end. Three forms are revealed when crude cell extracts are fractionated by a two-dimensional gel electrophoresis technique. Pulse-chase experiments show that the shortest and most alkaline form of S6 ... | 386,035 | [
0.02487139,
0.1576431,
-0.3640643,
0.02612065,
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0.02895042,
0.182901,
0.1146509,
0.07362746,
0.1189845,
0.05541039,
0.09793181,
-0.182259,
0.08852521,
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0.3082728,
-0.1862668,
0.1200394,
0.08336624,
0.08369453,
0.2905105,
0.1393578,
0.03587268,
0.01... |
Saccharomyces cerevisiae mutants defective in the maturation of ribosomal RNA. | Slow-growing mutants were isolated after mutagenesis of the osmotic-sensitive strain Saccharomyces cerevisiae VY1160. The isolated mutants in rich media have generation times from 300 to 400 min at 30 degrees C. Studies on the biosynthesis of rRNAX have shown, that the processing of 37S pre-rRNA in 6 of the slow-growin... | 386,037 | [
-0.1021501,
-0.1571824,
-0.2648298,
-0.2182388,
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0.041883,
-0.1523706,
0.1458687,
0.2947173,
0.1259825,
0.2111211,
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-0.2778403,
0.07670192,
-0.2800654,
0.2364433,
-0.04124589,
-0.08945789,
0.08170324,
0.09137124,
0.6980175,
0.1287973,
-0.08524123,
... |
Construction of an HpaI and HindII plasmid vector allowing direct selection of transformants harboring recombinant plasmids. | The construction of the vector plasmid PKN80 is described, which can be used as HpaI or HindII cloning vehicle with direct selection on transformants harboring hybrid plasmids. pKN80 carries the EcoRI.C fragment of phage Mu DNA coding for a killing function which is efficiently expressed upon transformation of pKN80 in... | 386,044 | [
-0.05339922,
-0.1484484,
-0.1464847,
-0.1105908,
0.228742,
-0.2962332,
-0.2216106,
0.174705,
0.2554199,
0.08478749,
0.04436177,
0.1446603,
0.01287998,
-0.07243843,
-0.1852627,
-0.05082265,
-0.4549564,
0.2225316,
-0.1580321,
0.30833,
0.04209627,
0.03144079,
0.06623452,
0... |
Membranous nephropathy: a radioimmunologic search for anti-renal tubular epithelial antibodies and circulating immune complexes. | In an effort to elucidate immunopathogenic of membranous nephropathy (MN), freshly collected sera from patients with biopsy proven MN were assayed of circulating immune complexes (ICs) by the Raji cell method and for anti-renal tubular epithelial (RTE) antibodies by a newly established radioimmunoassay (RIA) and by ind... | 386,150 | [
-0.01123272,
-0.0673359,
0.2060378,
-0.1525113,
0.07316155,
0.07572763,
-0.3572338,
0.3362558,
0.1106483,
0.06813621,
0.08060724,
0.3840176,
-0.04196391,
0.1451043,
-0.4143032,
-0.3124326,
-0.16575,
0.26685,
0.0600374,
0.02485183,
0.2115373,
0.07500228,
0.03939439,
-0.2... |
A detailed analysis of the 1-hour posttransplant renal biopsy. Its value in predicting future outcome of kidney transplants. | A detailed histological assessment of the 1-hour posttransplant biopsy has been made in 65 cadaver and related renal transplants. There was a lack of correlation between the numbers of polymorphonoclear leucocytes per glomerulus, the prescence and severity of thrombi, vascular changes, interstitial scars, the presence ... | 386,151 | [
-0.02901497,
0.02565273,
-0.6237208,
-0.1595013,
0.1511129,
-0.3221107,
0.2563006,
-0.08943094,
-0.2513909,
-0.1270083,
-0.04498608,
0.2116092,
0.1740568,
0.114248,
-0.3994176,
-0.2755445,
0.2504043,
0.3057115,
0.3192489,
0.5210568,
0.4509706,
0.3565844,
-0.1406171,
0.1... |
[Markers of type B viral hepatitis]. | The discovery of Australian antigen (HBsAg) has led to an increasing deal of knowledges about the virus of type B hepatitis (HBV); several markers of HBV have been detected and are becoming disposable for clinical and epidemiological purposes. The HBsAg is carried by 3 types of particulate structures discovered by elec... | 386,166 | [
-0.1329792,
0.1839628,
0.1340957,
0.2830583,
-0.1170102,
-0.5070558,
-0.08710578,
0.1092787,
0.09019727,
0.2193309,
-0.1459729,
0.168208,
0.01044451,
0.3245096,
-0.2405377,
-0.3651872,
-0.3451879,
0.03890982,
0.3021617,
0.2050761,
0.1147568,
0.1541989,
-0.3305076,
0.016... |
[Electrophoretic mobility of lymphocytes in multiple myeloma and bronchial cancer]. | The electrophoretic mobility of peripheral lymphocytes was studied in normal subjects and patients with myeloma and bronchial carcinoma. Distinct differences in anodic mobility were noted between the sub-populations in all three groups. Total lymphocyte migration was significantly slower in the two tumour groups. | 386,169 | [
-0.1929661,
-0.2126627,
-0.1601004,
-0.1925918,
-0.06250215,
-0.2509537,
-0.2638691,
0.1429506,
-0.1805812,
0.176035,
-0.04549311,
0.06826922,
0.1291779,
0.06155433,
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-0.4504377,
0.1046794,
0.1383617,
0.009078505,
0.4915341,
0.05998446,
0.1422361,
... |
[The hyperaminoacidurias with special reference to cystinuria]. | Increased urinary excretion of free amino acids is a sign which requires determination of the underlying cause. Physiological aspects of tubular transport with emphasis on the role played by transport proteins or carriers are briefly discussed. Subsequently we present a resumptive classification. In prerenal hyperamino... | 386,173 | [
-0.4043957,
-0.101691,
-0.1220446,
-0.05076639,
0.349646,
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-0.2342852,
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0.09271558,
0.2063013,
0.2724483,
0.1563882,
0.345883,
-0.4065998,
0.1299996,
-0.3671172,
0.08815114,
-0.1222923,
0.02075939,
-0.009341991,
0.2171559,
-0.07729756,
0... |
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