title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Nephrotoxicity and ototoxicity following irrigation of wounds with neomycin. | Renal failure and ototoxicity developed in two patients following wound irrigation with neomycin. In both patients the renal failure was reversible, but the deafness was progressive despite withdrawal of the neomycin. In one patient the serum neomycin concentration was still markedly elevated (42 microgram/ml) 2 days a... | 436,029 | [
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Analysis of sudden unexpected death in southern Ontario, with emphasis on myocarditis. | The records of all 2427 autopsies performed at the Brantford (Ont.) General and Paris (Ont.) Willett hospitals from Jan. 1, 1969 to Aug. 15, 1978 were reviewed. Of the 1299 cases of sudden unexpected death investigated by a coroner almost 28% were due to unnatural causes--violence or poisoning. The main cause of natura... | 436,050 | [
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"Dislocation of expectations" (management of violence on a general hospital psychiatric unit). | An approach to the management of potential violence on a General Hospital Psychiatric Unit is described as it evolved following analysis of the successful handling of a series of problem patients. The importance of an attitude of acceptance towards potentially violent persons is emphasized as is an orientation towards ... | 436,090 | [
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Hemodynamic adjustments in hypertensive patients developing circulatory congestion during beta-adrenergic blockade. | In the course of chronic treatment with a cardioselective beta-blocking agent (atenolol) 6 patients out of a series of 38 hypertensives developed signs of circulatory congestion. In spite of this, maximal exercise capacity was maintained. This resulted from hemodynamic readjustments at rest and exercise, where an incre... | 436,128 | [
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[Meconial peritonitis. Recordings about six observations. Diagnostic and prognostic value of calcifications. Therapeutic given off (author's transl)]. | The authors report six cases of meconium peritonitis with intra-abdominal calcifications; surgical intervention was successful in four. In five patients, fibrocystic desease of pancreas was eliminated. Presenting this report, it is their intention to underline the good prognosis of calcifications which generally elimin... | 436,191 | [
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[Reversed gastric tube oesophagoplasty in children (author's transl)]. | Over the last two years the authors performed 6 oesophagoplasties with reversed gastric tube, no splenectomy, retrosternal placement of the gastric tube and cervical termino-terminal anstomosis within a single operating interval. Only one death occurred, independent of the oesophagoplasy technique, as well as two minor... | 436,196 | [
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[Sphincter-oriented gluteal myoplasty, in the treatment of faecal incontinence in sacral agenesis and surgically treated anorectal malformations (author's transl)]. | The treatment of anal incontinence associated with anorectal malformations and sacral agenesis uses, in general, the levator ani. The role of the latter muscle can, however, only be passive, since it provides only suspension and angulation of the anorectal junction. Active control of continence may be obtained by means... | 436,199 | [
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The conduction system in hypoplasia of the aortic tract complex. | This is a study of the course of the conduction system in two cases of hypoplasia of the aortic tract complex, one with mitral stenosis and the other with mitral atresia. In both there was a posterior atrioventricular (AV) node which formed the AV bundle. In case 1 the bundle was short and bifurcated early. The branchi... | 436,223 | [
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Outliers in clinical chemistry quality-control schemes. | Results submitted to large-scale quality-control schemes are commonly judged against the mean and standard deviation (SD) of the results from other laboratories. It is desirable to ignore outlying values in estimating this mean and standard deviation, and results more than 2.5 or 3 SD from the mean are commonly rejecte... | 436,232 | [
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Method for determining thiocyanate in serum and urine. | We describe a method for rapid and specific measurement of thiocyanate in serum or urine. We separate thiocyanate from interfering compounds by adsorbing it on an anion-exchange resin that has special affinity for thiocyanate, then eluting with sodium perchlorate. The eluted thiocyanate is quantified by a modified Köni... | 436,233 | [
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Microchemical analysis for 13 constituents of plasma from healthy children. | Normal values for 13 chemical constituents of plasma were estimated from results for 837 presumably healthy children. Ninety microliters of specimen was analyzed for lactate dehydrogenase, aspartate aminotransferase, alkaline phosphatase, inorganic phosphorus, total calcium, total cholesterol, total proteins, albumin, ... | 436,235 | [
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Significance of "high" acid phosphatase activity in the serum of normal children. | Serum acid phosphatase activity in normal children (newborn to 18 years) is several fold that in normal adults. Activity is age-related but not sex-related. The isoenzyme pattern in children is similar to that in adults and contains no prostatic fraction. Quantitatively, most of the enzyme activity in the serum of chil... | 436,239 | [
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An automated amidolytic assay of thrombin generation: an alternative for the prothrombin-time test. | An automated method is presented for the determination of thrombin generation in plasma during activation by thromboplastin. The thrombin generated is allowed to split the chromogenic substrate Tol-Gly-Pro-Arg-pNA yielding p-nitroaniline. The increase in absorbance at 410 nm is recorded. This assay may serve as a speci... | 436,285 | [
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Increased CK-BB concentrations in serum following cardiac surgery. | We measured the BB isoenzyme of creatine kinase by a specific radioimmunoassay in the serum of 47 patients following cardiac surgery. A sharp increase in CK-BB occurred immediately after surgery, with rapid return to baseline by the fourth post-operative day. This data, along with other reports in the literature, sugge... | 436,298 | [
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L-thyroxine treatment of diffuse non-toxic goitre evaluated by ultrasonic determination of thyroid volume. | The effect of a daily dose of 150 micrograms l-thyroxine for one year was studied in forty-five patients with diffuse non-toxic goitre. Thyroid volume was evaluated by ultrasonic scanning. A decrease in the median value of the thyroid volume of about 20% was found after 3 months of therapy and no further change in the ... | 436,302 | [
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Acute dapsone intoxication: a case with prolonged symptoms. | A 45-year-old man ate about 10 gm of dapsone (DDS). After initial vomiting marked methemoglobinemia with cyanosis, headache, and confusion developed. Methemoglobinemia subsided 7 days after ingestion when the concentrations of DDS and monoacetyldapsone (MADDS) were at the therapeutic level. Signs of hemolysis appeared ... | 436,385 | [
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Fenfluramine poisoning. | In a series of 53 fenfluramine intoxications (15 taken from the literature), 10 were lethal after doses of 28.7--70 mg/kg of body weight. Cardiac arrest occurred 1--4 hr after ingestion in 9 cases; all these 9 patients died. Two out of 3 patients with more than 15 mg/kg had coma and convulsions. Other frequent signs we... | 436,387 | [
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A prospective study of mitral valvular prolapse in young men. | A cardiac history, a physical examination, an electrocardiogram, phonocardiograms in the supine and standing positions, and an M-mode echocardiogram were obtained in 100 randomly selected, presumably healthy, male medical students (mean age, 26 years). Four percent met standard echocardiographic criteria for mitral val... | 436,482 | [
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Irradiation-induced pericarditis. | Three patients with pericarditis following therapeutic irradiation for malignant tumors were studied at autopsy. In one subject, death occurred five days after the last dose of radiation. The pericardial involvement was characterized by fibrinous exudation. This was more marked in degree over the right side of the hear... | 436,483 | [
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Bronchostenosis due to sarcoidosis: a cause of atelectasis and airway obstruction simulating pulmonary neoplasm and chronic obstructive pulmonary disease. | Ninety-nine patients with clinically and histopathologically established sarcoidosis were studied during the period of January 1971 to October 1977 using the bronchoscope. In 32 patients, biopsy of the bronchial mucosa showed a microscopic picture typical of sarcoidosis. In eight (8 percent) of the 99 patients, severe ... | 436,515 | [
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Historic and angiographic features of young adults surviving myocardial infarction. | Sixty-eight survivors of myocardial infarction occurring before the age of 36 years were studied using selective coronary cinearteriograms, regardless of symptoms. Three groups of patients were delineated; 56 patients (82 percent) had obstructive coronary arterial disease, nine (13 percent) had normal coronary arteries... | 436,516 | [
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Pulmonary reaction to upper mantle radiation therapy for Hodgkin's disease. | To study the effects of upper mantle radiation therapy on pulmonary function, forced expiratory volume in one second (FEV1), vital capacity (VC), inspiratory capacity (IC), diffusing capacity for CO (DLCO) and diffusion per unit of alveolar volume (DL/VA were determined in 28 patients with Hodgkin's disease, stages 1--... | 436,520 | [
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Secundum atrial septal defect and significant mitral regurgitation: incidence, management and morphologic basis. | To better understand the association between mitral regurgitation and secundum atrial septal defect and to clarify the evaluation and management of these patients, the records of 235 adult patients with atrial septal defect were reviewed. Ten patients (4 percent) had significant mitral regurgitation defined by clinical... | 436,522 | [
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On the pathology of experimental hydrocephalus induced by artificial increase in endoventricular CSF pulse pressure. | In lambs, acute and chronic communicating hydrocephalus has been created by merely increasing the amplitude of the intraventricular cerebrospinal fluid (CSF) pulsations, leaving the mean CSF pressure unchanged. The pathologic changes occurring in this type of hydrocephalus do not differ qualitatively from those observe... | 436,567 | [
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[A simple method for determining blood-glucose levels in diabetic out-patients (author's transl)]. | 24 hour blood-sugar profiles were obtained in 25 diabetic out-patients. The samples were obtained by the patients themselves even when at work, the glucose-level measurements in the laboratory. The relative differences between duplicate values was less than 10%. The results obtained made it possible to alter the treatm... | 436,653 | [
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Characterization of cholinergic control of vasopressin release by the organ-cultured rat hypothalamo-neurohypophyseal system. | Acetylcholine and nicotine stimulated vasopressin (VP) release from the organ-cultured rat hypothalamo-neurohypophyseal system (HNS). Nicotinic antagonists, hexamethonium, tetraethylammonium chloride, and trimethaphan blocked VP release in response to acetylcholine and nicotine. A muscarinic agonist, methacholine, was ... | 436,724 | [
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Steroid metabolism by the lung: conversion of dihydrotestosterone to 5 alpha-androstan-3 alpha, 17 beta-diol by rat lung tissue in vitro. | The potential of lung tissue of adult male rats metabolize dihydrotestosterone (DHT) in vitro was examined. Within 3 min, a homogenate of 100 mg lung tissue, cleared of blood by perfusion before homogenization, metabolized 90% of the [3H]DHT substrate. Appoximately 80% of the DHT was converted to 5 alpha-androstan- alp... | 436,725 | [
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Aldosterone, deoxycorticosterone, corticosterone, and prolactin changes during the lifespan of chronically and spontaneously hypertensive rats. | Male and female spontaneously hypertensive rats (SHR), which develop hypertension spontaneously with maturation, were autopsied at select time intervals from weaning to 28 months. Their blood pressure began to rise steeply at 4--5 weeks, reaching a zenith of 180--240 mm Hg after 4 months. Elevated blood pressures were ... | 436,781 | [
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0.2328953,
0.08842053,
0.0136049,
0.00833251,
-0.3827315,
0.1197217,
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0.01792493,
0.5710427,
0.3083091,
0.284298,
0.06805545,
-0.2630817,
... |
Effects of calcitonin and other hormones on bile calcium excretion in thyroparathyroidectomized rats. | The effects of calcitonin (CT) and other hormones on the bile calcium excretion after a single intraperitoneal administration of calcium (4.0 mg/100 g BW) was investigated in thyroparathyroidectomized rats. Porcine, salmon, and synthetic eel CT (80 MRCmU/100 g BW, respectively) markedly increased the bile calcium excre... | 436,794 | [
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... |
Fluctuations in proline and other free amino acids during the mitotic cycle of the myxomycete Physarum polycephalum. | 1. During synchronous growth of the acellular slime mould Physarum polycephalum the free amino pool had two maxima, one of 650 units [nmol/plasmodium dry weight (mg)] at metaphase and the other of 780 units in mid G2 with minima of 550 units before and after mitosis. 2. Proline formed 20--25% of the total pool with asp... | 436,826 | [
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0.4208118,
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The polysomal proteins of L cells. Discrimination between the structural ribosomal proteins, the exchangeable ribosomal proteins and the non-ribosomal proteins by two-dimensional dodecylsulfate electrophoresis and autoradiography. | Three groups of proteins can be clearly discriminated in the total protein of L cell polysomes by selective labelling in the presence of low doses of actinomycin D and two-dimensional polyacrylamide/dodecylsulfate gel electrophoresis followed by autoradiography: (a) structural ribosomal proteins which are not labelled ... | 436,829 | [
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0.2391245,
0.1126088,
-0.0587705... |
Property and activity of mycoloyl esters of methyl glucoside and trehalose. Effect on mitochondrial oxidative phosphorylation related to organization of suspensions and to acyl-chain structures. | Methyl alpha-D-glucoside and alpha, alpha'-D-trehalose acylated on their primary hydroxyl group by alpha-alkyl-beta-hydroxy acids (mycolic acids) with 18, 32 and more than 80 carbon atoms were studied. These cord factors and analogues when dispersed in water gave hydrated and organized phases which bore resemblances an... | 436,835 | [
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... |
Fast kinetic studies on the allosteric interactions between acetylcholine receptor and local anesthetic binding sites. | Preincubation of receptor-rich membrane fragments from Torpedo marmorata with tertiary amine local anesthetics and several toxins such as histrionicotoxin, crotoxin and cerulotoxin, modifies the amplitude and time course of the relaxation processes monitored upon rapid mixing of the membrane fragments with the fluoresc... | 436,844 | [
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0.4043013,
0.3071342,
-0.04817886... |
Detrusor hyperreflexia in multiple sclerosis. Alleviation by a combination of imipramine and propantheline, a clinico-laboratory study. | 16 patients with multiple sclerosis, complaining of urgency, frequency and urge incontinence were studied urologically. They all suffered from detrusor hyperreflexia. We managed to improve this disturbance by lowering the parasympathetic tone and at the same time increasing the sympathetic tone of the urinary outlet, u... | 436,862 | [
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0.1211478,... |
Histological grading of prostatic carcinoma and its clinical evaluation. | The clinical control of patients with T1--T3, N0--M0 prostatic carcinomas allows us to draw the following conclusions regarding the grading. (1) The grading of the primary tumor is of great help in establishing the prognosis. (2) The results of the various applied treatments, like radical prostatectomy, radiation, and ... | 436,866 | [
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0.1111874,
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0.1884476,
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0.... |
Experimental ureteral replacement with a vascularized gastric tubule. | Total ureteral substitution had been performed with a pedicled gastric flap shaped as a tubule in 6 dogs. No dilatation was found at X-ray controls. No metabolic changes were recorded. The HCl secretion diminished the possibility of an infecting reflux. | 436,879 | [
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0.03286067,
0.01971183,
0.2430741,
0.05370303,
0.01109... |
Pharmacologic response to pentobarbital in passively immunized mice. | Rabbits were actively immunized using a barbiturate--BGG conjugate as the immunogen. The antiserum obtained from actively immunized rabbits was administered intravenously to mice to accomplish passive immunization. The antibody binding capacity for 3H-phenobarbital was shown to be sustained in passively immunized mice ... | 436,935 | [
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0.4564662,
0.08503268,
0.4476743,
0.04788394,
0.01772414,
0.0241864... |
Digoxin-induced decrease in intraocular pressure in the cat. | A constant intravenous infusion of digoxin (2 micrograms/kg/min) to alpha-chloralose-anesthetized cats produced a progressive decrease in intraocular pressure with increasing doses of digoxin between 60 micrograms/kg and drug-induced ventricular arrhythmia which occurred at a mean dose of 172 micrograms/kg. Digoxin eli... | 436,941 | [
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0.1136533,
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0.004021925,
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Disparity tuning and binocularity of single neurons in cat visual cortex. | Activity from single neurons in the visual cortex of anaesthetized and paralyzed cats were recorded in response to monocular and binocular stimuli of different retinal disparities. Three different types of disparity sensitive neurons were found, characterized by (1) a response maximum near zero disparity, (2) a respons... | 436,983 | [
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0.00218056,
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0.4534514,
0.2300001,
... |
Ascending projections of nociceptor-driven Lamina I neurones in the cat. | Single unit activity has been recorded from nociceptor-driven Lamina I neurones in the lumbar spinal cord of chloralose anaesthetized and gallamine paralysed cats. Ninety-four nociceptor-driven Lamina I neurones were identified by their superficial location in the dorsal horn and their ability to respond only to noxiou... | 436,985 | [
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... |
Oscillatory after-potentials and triggered-automaticity in mammalian ventricular muscle fibres at high resting potentials. | Oscillatory after-potentials and triggered-automaticity were observed in dog ventricular muscle fibres when the fibres were exposed to K+-free,high-Ca++-solutions after K+-free,Ca++-free perfusion. They appeared at membrane potentials more negative than--60 m V. | 437,031 | [
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-0.0702... |
Lead metabolism in lactation. | A 2-fold increase in lead absorption was observed in lactating animals which received 2 mg Pb/l in drinking water. About one-half of the absorbed lead was transferred to the litters. | 437,043 | [
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0.... |
Evidence for synergism in steroid hormone-receptor association. | A number of glucocorticoids stimulated oestradiol binding to liver cytosol receptor; oestradiol activated glucocorticoid receptor association at a time when it reversed triamcinolone mediated increase in liver glycogen synthesis. | 437,056 | [
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... |
[Effect of phenobarbital on the embryotoxic action of 2-methyl-4-chlorophenoxyacetic acid]. | Single administration of 2-methyl-4-chlorophenoxyacetic acid (2M-4C) to albino rats on the 9th and 10th day of gestation produces a teratogenic and embryotoxic action. A preliminary administration of phenobarbital in a dose of 80 mg/kg for 3 days largely reduced the embryotoxic effect of the drug, this manifesting itse... | 437,086 | [
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0.2976033,
0.3488746,
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0.... |
The structural organization of mouse chromatin as a function of age. | Chromatin is organized into a repeating structure (nucleosome) made up of proteins and DNA. Micrococcal nuclease and DNAase I have been used to probe this structure in nuclear populations from three tissues (liver, brain, and heart) of the inbred mouse strain C57BL at different ages. For those parameters examined, for ... | 437,140 | [
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0.1508748,
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-0.317... |
Age-related changes in function of transfer ribonucleic acid of rat livers. | Changes in transfer ribonucleic acids during aging could be caused by alterations in regulation or mutation and give rise to slower and less accurate protein synthesis. Rodent liver parenchymal cells, purified from disaggregated livers, do decrease in ability to incorporate labeled amino acids during aging. Moreover, o... | 437,142 | [
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... |
Hormonal considerations in early normal pregnancy and blighted ovum syndrome. | The hormonal profiles of six pregnancies which terminated in miscarriage with the blighted ovum syndrome have been studied and compared with those of a group of patients similarly studied who had clinically normal pregnancies terminating in live birth at term. The serum chorionic gonadotropin (HCG) values were below no... | 437,159 | [
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0.1263793,
0.2516219,
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-0.06130063,
0... |
[Cerebral water and electrolytes during changes in the osmolarity and volume of the extracellular fluid]. | The increase of osmolarity in the blood serum after administration of polyethylenglycol-400 (PEG) as well as the sharp increase of the renal loss of fluid under the influence of furosemide insignificantly affected the water contents in the white and grey brain substance. A slight dehydration of the grey substance occur... | 437,191 | [
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0.3714682,
0.1657903,
0.04623216,
-0.09557778... |
[Hemodynamic structure of pressor reactions to vasoactive substances]. | In cats, similar changes of the blood pressure had different hemodynamic structures under the influence of catecholamines or angiotensin. Adrenalin was able to evoke a pressor response by means to either caridac or vascular factor. In the former case, the increase in the cardiac output was induced both by an increasing... | 437,201 | [
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... |
A comparison of controlled-release aminophylline (Phyllocontin Continus tablets) and sympathomimetic bronchodilators. | In a crossover trial on twenty-four patients with reversible airways obstruction the rise in FEV1 on Phyllocontin Continus tablets (15%) was comparable to that achieved with Alupent tablets (14%). The usage of inhaled salbutamol and frequency of attacks of wheeziness were both greater when the patients were taking Alup... | 437,308 | [
-0.02334438,
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0.1833242,
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0.04080949,
-0.04473079,... |
Behavioral effects of rotation between lactating and nonlactating females. | Rat pups stunted by housing only 8 hr daily with lactating females and 16 hr with nonlactating foster mothers showed a delay in returning to their nest from other parts of the home cage. This delay was not due to changes in activity level or to lack of attraction to the nest, but appeared to be perceptual in nature. Bo... | 437,363 | [
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0.1922588,
0.1835915,
... |
The effect of age on insulin-degrading activity in rat tissue. | Insulin-degrading activity was measured in the 100,000g supernatant fraction of muscle, liver, and kidney from rats of varying ages. Young animals (four weeks old) had the highest activity in all three tissues. By seven weeks of age the activity in both muscle and liver had decreased significantly as compared with four... | 437,372 | [
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0.08721606,
0.6259331,
0.1524771,
0.2239685,
-0.02840023... |
Theophylline: potentiation of arginine-induced somatostatin release from the isolated rat pancreas. | Somatostatin's release from the isolated rat pancreas was studied using a perfusion technique. Arginine at a concentration of 19 mM produced a biphasic increase in somatostatin release from the perfused rat pancreas. Both first and second phases of somatostatin's increase are significantly higher in the presence of 1 m... | 437,374 | [
-0.09077671,
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0.1763955,
0.06224323,
0.0950145... |
Small intestinal biopsy in a patient with Crohn's disease of the duodenum. The spectrum of abnormal findings in the absence of granulomas. | The case is reported of a patient who presented with an occult anemia that was due to Crohn's disease of the duodenum. The initial evaluation revealed low serum levels of iron, folate, and carotene, and a small bowel series was abnormal but not diagnostic of Crohn's disease. Numerous small intestinal biopsy specimens w... | 437,405 | [
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Comparison of acid secretion rates measured by gastric aspiration and by in vivo intragastric titration in healthy human subjects. | In nine healthy subjects acid secretion rates, measured first by gastric aspiration and then by in vivo intragastric titration to pH 5, were compared. In vivo intragastric titration was initiated by instilling 50, 100, or 700 ml saline (pH 5) into the stomach, followed by a continuous intragastric saline infusion at 3.... | 437,422 | [
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0.1366719,
-0.1075098,
0.0174... |
Permeability of the diaphragm and fluid resorption from the peritoneal cavity in the rat. | The ability to remove fluid from the peritoneal cavity is greatly impaired in rats after sealing the diaphragm (abrading such that fibrous tissue forms). The in vivo resorptive capacity of rats with sealed diaphragms was significantly reduced from 12.3 +/- 1.77% . hr-1 in controls to 5.05 +/- 2.53% . hr-1 in rats with ... | 437,426 | [
-0.004838534,
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0.04386069,
0.1049... |
Leukocyte migration inhibition in response to biliary antigens in primary biliary cirrhosis, sclerosing cholangitis, and other chronic liver diseases. | The leukocyte migration inhibition test has been used to investigate cellular immune responses to antigens in a protein fraction (BPF) of normal human gallbladder bile in patients with a variety of intra- and extrahepatic diseases. Inhibition of leukocyte migration in the presence of BPF was observed in 30 (81%) of 37 ... | 437,430 | [
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... |
Epidemic gastritis with hypochlorhydria. | Seventeen of 37 healthy volunteers participating in studies of acid secretion and 1 patient with Zollinger-Ellison syndrome became rapidly and profoundly hypochlorhydric. A mild illness with epigastric pain occurred in 9 subjects, usually several days before detection of hypochlorhydria. Gastric mucosal biopsy specimen... | 437,444 | [
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0.... |
[Discussion of a spontaneous uretero-colonic fistula with stone formation in the rectum (author's transl)]. | The unusual course of a vesico vagino-rectal fistula with spontaneous development of a uretero-colonic fistula in a patient with carcinoma of the cervix is presented. After a double-barrel colostomy had been performed kidney function remained normal for many years. Because of incontinence of the anal sphincter the urin... | 437,455 | [
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0.5206878,
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0.53... |
[Seasonal fluctuations in the sex ratio of new borns and the influence of the declining birth rate on the sex ratio (author's transl)]. | Seasonal fluctuations in the sex ratio of new borns are investigated. The largest predominance of male deliveries over female deliveries was found to be during the conception months May-June with an almost constant number of deliveries. The highest value was in June. Seasonal maximum of the male to female sex ratio is ... | 437,460 | [
0.003347558,
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0.4482601,
0.1742448,
-0.05157617,... |
[Folate- and iron-deficiency in pregnancy (author's transl)]. | In an open study the influence of a pure iron-therapy (Aktiferrin) and a combined iron-folic-therapy (Aktiferrin F) on the blood and the folate levels in the serum of 60 anaemic pregnant women was compared. The prophylactic administration and the therapy of iron and folate acid in pregnancy is demanded because of the r... | 437,473 | [
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0.23... |
[Pregnancy and delivery combined with hereditory angioneurotic edema (author's transl)]. | Two deliveries in a patient combined with hereditory angioneurotic edema are reported. Although even the smallest trauma can lead to life threatening edema the tendency to edema is reduced during pregnancy. Neither in the vagina nor the vulva the deliveries caused edema. The episiotomy did not cause a concomitant edema... | 437,476 | [
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... |
[The increasing number of extra marital deliveries a sociological phenomenon (author's transl)]. | Recent statistical results show an increase in extra-marital life birth. The number of older women between 26 and 28 years of age who have extra-marital deliveries has especially increased. The number of single parent families has more than doudled in the last three decades. The number of 26--28 year-old women who marr... | 437,477 | [
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0.1492628,
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0.3500803,
0.2369741,
0.14403... |
Aldolase activity and cross-reacting material in lymphocytes of aged individuals. | Aldolase activity was determined in human lymphocytes from 21 donors aged 18-84 years. The lymphocyte extracts contained exclusively aldolase A isozyme. No significnat difference in enzyme activity between adult (18-41 years) and old (56-84 years) age groups was observed. There was also no significant decrease with age... | 437,507 | [
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0.6174768,
0.2304177,
0.3622233,
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... |
Relationship between endotoxaemia and protein concentration of ascites in cirrhotic patients. | Endotoxaemia was investigated by the Limulus assay in 42 cirrhotic patients with ascites and in 33 without ascites. The incidence of endotoxaemia in the former group (59.5%) was significantly (P less than 0.05) higher than in the latter (36.4%). Correlation between endotoxaemia and specific gravity and concentrations o... | 437,553 | [
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0.06018798,
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-0.0... |
Amylase activity in human bile. | The mean amylase level in 42 human bile samples was 154 IU/l and there was no significant difference in the amylase activity of 32 paired serum and bile samples. Estimation of the amylase thermolability of bile showed it to be similar to that of serum. This suggests that the amylase activity in bile may have filtered t... | 437,555 | [
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-0.0286932... |
Demonstration of dehydrogenase activities in paraffin sections. | The possibility of demonstrating the activity of respiratory enzymes in paraffin sections was studied. Unfixed pieces of nervous tissue were incubated at 4 degrees C, 20 degrees C, 37 degrees C and 56 degrees C for various periods ranging from 1 to 24 hours. After dehydration, the tissue pieces were mounted in paraffin... | 437,580 | [
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... |
[Decrease of ACh response in isolated duodenum from SART stressed (repeated cold stressed) mice (author's transl)]. | ACh response in the isolated duodenum from SART stressed (repeated cold stressed) mice was remarkably decreased in comparison to normal mice 5 days after onset of loading SART stress, and maximal contraction in SART stress mice duodenum was about 37% of that in non-stressed mice. Pilocarpine and KCl responses were also... | 437,583 | [
-0.08336773,
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0.4784499,
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-0.129621... |
[Effects of vitamin B complex in functional changes of the peripheral nerves of alloxan-induced diabetic rats (author's transl)]. | Neurophysiological properties of the peripheral nerves of alloxan-induced diabetic rats and effects of vitamin B complex (V) were studied. Alloxan monohydrate was administered to Wistar (38 mg/kg, i.v.) and Sprague-Dawley (SD, 45 mg/kg, i.v.) rats. In Wistar diabetic rats (blood sugar level: more than 400 mg/dl for 6--... | 437,585 | [
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0.0... |
A chromatography system for drug identification. | A classification system is described for drugs using thin-layer chromatography (TLC), gas-liquid chromatography (GLC) and ultraviolet (UV) spectrophotometry. The TLC classifications are based on division of the plate into zones relative to a set of mixed drug standards. The GLC classification is based on Kovats' retent... | 437,620 | [
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0.1347317... |
Effects of possible beta-cell membrane label, metahexamide-isothiocyanate, on insulin release. | To synthetize a specifically and covalently reacting label for the sulfonylurea receptor site, the sulfonylurea metahexmide was converted to its isothiocyano-derivative (MITC), and the effects of MITC on insulin release from the perfused rat pancreas were studied. MITC (2 micrometer) stimulated a large insulin release ... | 437,672 | [
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... |
Absorption of protamine-insulin in diabetic patients. I. Preparation and characterization of protamine-125I-insulin. | Protamine-125I-insulin with low specific radioactivity was prepared using 125, 127I-insulin, 0.2 I/mole. The preparations were characterized by disc electrophoresis, isoelectric focusing and analytical gel chromatography in order to evaluate the suitability of 125I-insulin as marker for insulin in protamine-insulin. Th... | 437,686 | [
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... |
Role of ovarian secretion in the development of dysfunction in the regulation of luteinizing hormone secretion in female rats exposed to constant illumination. | Female rats in constant illumination (LL) fail to show the facilitation of LH release following steroid administration that is characteristic of animals in normal lighting. To determine whether this effect is mediated through changes in ovarian function, rats were spayed either at the time of placement into different l... | 437,689 | [
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Failure to demonstrate antigonadotrophic activities of arginine vasotocin in the mouse. | Arginine vasotocin (AVT) has previously been proposed to be a pineal hormone which reduces reproductive competency in mammals. The effects of AVT on the growth of immature reproductive organs of the mouse have been studied using blind study techniques. Evidence is presented which fails to support the proposed role of A... | 437,691 | [
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... |
Extended hospital care as treatment of choice. | A review of the histories of six patients who failed to adapt to community living after hospital discharge identified six factors that are predictive of serious maladjustment in the community. The are the absence of a family or soical network, repeated threats of violent behavior, previous hospitalization, poor previou... | 437,713 | [
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... |
Israeli delivery system provides outreach care for nomadic Bedouins. | Israeli's Ministry of health and the Kupat Holim have penetrated cultural barriers, solved logistics, and extended curative and preventive care to a Bedouin population living in Beersheba, outlying villages and small cities, and the Negev Desert. | 437,730 | [
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0... |
When enough is enough. | The goals of hospitals and hospices are not necessarily incompatible, and hospice care may be an opportunity for hospitals to further humanize their services. | 437,732 | [
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0.154304... |
Checklist for materials managements. | Two-part report from the General Accounting Office shows how to evaluate and improve the materials management function in hospitals. | 437,736 | [
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... |
New concepts of chronic pain and their implications. | When chronic pain fails to respond to therapy, the approach often have been based on outmoded concepts of the nature of pain. The current unified pain theory takes into account recent biochemical advances and can serve as a basis for more effective diagnostic and therapeutic approaches. Various treatment modalities are... | 437,749 | [
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... |
Immunologic mechanisms in nephritogenesis. | At least two different immunopathologic pathways that together account for most clinical nephritis have been delineated. Most common is the situation in which antigen-antibody complexes form in the circulation and lodge in renal basement membranes. The second involves antibodies to specific kidney structures. Both may ... | 437,758 | [
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... |
Antibiotic-associated colitis. | Pseudomembranous colitis, a relatively uncommon and sometimes severe diarrheal disease, recently has been linked to the administration of a number of broad-spectrum antibiotics. The cause has now been identified as a spore-forming clostridial species not previously recognized as a human pathogen. Since the organism is ... | 437,759 | [
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... |
"Complete" trisomy 5p; de novo translocation t(2;5)(q36;p11) with isochromosome 5p. Case report and review of the literature. | A case of complete trisomy 5p due to a de novo translocation t(2;5)(q36;p11) with an isochromosome 5p is described. Complete trisomy 5p has been reported only once (Brimblecombe et al., 1977). The confusing literature relating to partial trisomy 5p is reviewed. Comparison of our case with the patients reported by Brimb... | 437,770 | [
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... |
Trisomy 6q25 to 6qter in a severely retarded 7-year-old boy with turricephaly, bow-shaped mouth, hypogenitalism and club feet. | Trisomy for a small terminal segment of chromosome 6q produces a characteristic syndrome of malformations and dysmorphic signs which, on the basis of comparison with a previously published case, may be suspected on clinical grounds. The present case concerns a 7-year-old boy, the son of a carrier mother t(6;14)(q25;qte... | 437,771 | [
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0.3365641,
0.1343714,
0.1296847,
-0.07... |
Neuraminidase treatment reveals sialic acid differences in certain genetic variants of the Gc system (vitamin-D-binding protein). | Common and rare Gc phenotypes were analyzed by agarose gel electrophoresis immunofixation and by isoelectric focusing immunofixation before and after neuraminidase treatment. There is a difference between Gc types with double-band and with single-band patterns. Neuraminidase affects only Gc types with a double-band pat... | 437,784 | [
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0.2127628,
0.1110642,
0.4081038,
-0.4327352,
... |
The relative capacity of corneal, heart, kidney and skin cells to stimulate allogeneic lymphocytes. | In stimultaneous experiments, the ability of inbred Wistar-Furth rat corneal cells to stimulate inbred Fisher rat lymphocytes in mixed culture was compared with the stimulatory capacity of the same number of Wistar-Furth skin, kidney, heart and lymphocyte cells. The tissue cells were dissociated and after inhibition by... | 437,826 | [
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0.3546733,
0.5557868,
0.3323543,
-0.05980818,
-... |
Stability of peripheral blood lymphocyte count and E-rosette forming lymphocytes in healthy adults. | Highly reproducible peripheral blood lymphocyte (PBL) count and percent E-rosette forming lymphocyte (%E-RFL) assays were developed by modifying existing procedures. PBL count assay variation was reduced by using replicate electronic white blood cell (WBC) counting and 2,000 WBC differentials. The %E-RFL assay modifica... | 437,827 | [
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0.4141727,
0.03507621,
0.1663036,
0.1640564,
-0... |
Uptake of 125I-labelled C3a by cultured human endothelial cells. | The interactions of C3a anaphylatoxin with vascular endothelium were studied in vitro using human endothelial cells in culture and 125I-labelled human C3a. Cultured endothelial cells took up 125I-C3a in a time- and concentration-dependent manner and inactivated it. Uptake was not associated with binding to specific rec... | 437,829 | [
0.04506536,
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0.2804546,
0.06939527,
0.6155924,
0.1210065,
... |
The metabolism of nucleic acids in mice. | The metabolism of three forms of nucleic acid, native-DNA (N-DNA), single strand DNA (SS-DNA), and polyinosinic-polycytidylic acid (poly I : C), was investigated in vivo in randomly bred Swiss-Webster mice. Clearance of these substances from the circulation and tissue localization were determined at selected time inter... | 437,834 | [
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0.1823611,
0.1095091,
-0.1698333,
... |
The localization of allogeneic lymphoid cells in relation to antibody-mediated immunosuppression. | Carbon blockade of mice did not affect cytotoxic antibody production after immunization with allogeneic cells, nor did it affect the immunosuppressive activity of alloantibody. Though it inhibited the alloantibody-mediated increase in hepatic localization of allogeneic lymphoid cells it had no effect on the normal hepa... | 437,842 | [
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0.02810339,
0.02035716,
0.4445253,
0.1294882,
0.3514604,
-0.04045232,
... |
Synthetic peptide chemotactic factors for neutrophils: the range of active peptides, their efficacy and inhibitory activity, and susceptibility of the cellular response to enzymes and bacterial toxins. | The chemotactic activity for neutrophil leucocytes of twenty-six peptides of varied sequence, of which the majority were N-formylated, was assessed by determining the concentration at which each was maximally active and the efficacy of each peptide at that concentration. These two measures of activity did not correlate... | 437,845 | [
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0.1129589,
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0.06631017,
0.571759,
-0.01978303,
0.003414082,
-0.1203764,
... |
Alterations of some chemical constituents in blood and liver of jowar fed chicks. | The affect of feeding jowar (Sorghum vulgare) was investigated in day old chicks for the periods of 10 and 30 days. Similar chicks serving as controls were fed on Hindlever Poultry feed. The jowar fed chicks showed marked reduction in growth, poor development of comb and feathers, and symptoms of nicotinic acid deficie... | 437,868 | [
-0.04710491,
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0.2330716,
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0.06312796,
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0.4934434,
0.2660462,
0.38674,
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0.2794535,
0.2783395,
0.1873132,
0.2942252,
0.4335474,
-0.2782539,
-0... |
Lognormal distribution in physical work capacity in young healthy males. | This paper evaluates the statistical distribution of physical work capacity (Vo2 max) in young healthy males. For this purpose, the normally of Vo2 max data, collected on two random samples consisting of 123 and 120 young healthy male volunteers was tested. It is concluded that physical work capacity follows lognormal ... | 437,869 | [
-0.04092428,
0.0775295,
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0.04045592,
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-0.3545009,
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0.2145641,
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-0.1975814,
0.4973051,
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0.2395312,
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0.2783801,
0.3055189,
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-0.170025,
-0.0825586,
0.3055348,
-0.2155933,
... |
[Infections caused by the so-called atypical mycobacteria (author's transl)]. | A number of cases of patients in whom the so-called atypical mycobacteria were identified in our institute are presented briefly in this report. Predisposing factors such as occupation and existing tissue damage, particularly in prolonged respiratory tract diseases, play a significant role in the establishment of the i... | 437,896 | [
-0.2343105,
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0.09632524,
0.1431882,
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-0.1124081,
0.1617241,
0.0328622,
0.1371554,
0.1206508,
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-0.2919813,
0.07524987,
0.1250365,
0.2906303,
0.2808884,
0.1083614,
-0.05188508,
... |
Chemotaxis inhibition induced in polymorphonuclear neutrophils by soluble immune complexes. | Complement-independent chemotactic factor(s) may be generated in fresh guinea pig serum by contact with soluble Ab1Ag1 immune complexes. This activated serum is equally efficient in inducing an unresponsive state in polymorphonuclear neutrophils (PMN) to subsequent chemotaxis challenge with sera containing C-dependent ... | 437,907 | [
-0.01744975,
0.121616,
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0.1235316,
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0.0738127,
-0.03527251,
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0.04465801,
-0.2371724,
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-0.6811541,
-0.08890288,
0.02323848,
0.3810078,
-0.09250163,
0.05855443,
-0.2044014... |
Inverse correlation between cell-surface adhesiveness and malignancy in mouse fibroblastoid cell lines. | The correlation between tumorigenicity and cell-surface adhesiveness was investigated in eight mouse fibroblastoid cell lines. Four of the lines (Mc 11-Mc 15) were derived from mouse MC-induced fibrosarcomas, two were derivatives of L cells (A9, A9HT), and two (clone 3 and clone 7 H7F4) were obtained by fusion of A9HT ... | 437,920 | [
-0.3521442,
0.07007612,
0.1546326,
-0.3316923,
0.1027149,
0.02733877,
-0.0621307,
0.2999761,
0.2832907,
0.2788639,
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0.03580299,
0.1817644,
-0.06234061,
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-0.2910319,
-0.1388584,
-0.09976046,
-0.1415059,
0.2897578,
0.5600309,
0.0763466,
-0.2726099,
-... |
Oesophageal cancer and alcohol consumption; importance of type of beverage. | The role of alcohol consumption in oesophageal cancer in Normandy has been studied by a retrospective study of 312 male cases and 869 controls. The linear relationship between the logarithm of risk and overall daily alcohol consumption was confirmed after adjustment for tobacco. The role of each specific alcoholic beve... | 437,923 | [
-0.3662472,
-0.03309051,
-0.5043814,
0.01938935,
0.1404064,
-0.2221915,
-0.2387861,
0.2498562,
0.1540934,
0.05134597,
0.3299946,
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0.3565398,
-0.4647089,
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0.04538376,
0.1908747,
-0.1709886,
-0.2056707,
0.2589103,
0.009816967,
-0.171522,
... |
Neuroendocrine cells in serially passaged rat stomach cancers induced by MNNG. | Five gastric carcinomas, induced in inbred Wistar rats by oral administration of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) dissolved in drinking water, were successfully transplanted to isologous rats. The transplants grew to a size of 10 to 35 mm in diameter within 8 to 25 weeks of implantation. In one case, serial ... | 437,928 | [
-0.2962736,
-0.03828144,
-0.2973857,
-0.6560683,
0.3240393,
-0.2361028,
-0.1420704,
-0.1476395,
0.2052252,
0.2290458,
0.2387335,
-0.06746112,
-0.1519405,
-0.2267202,
-0.1397426,
-0.01563719,
-0.02748893,
0.05778683,
0.2603103,
0.3225191,
0.3255555,
0.1072361,
-0.1282973,
... |
Circadian rhythmicity in rat intestinal villus length and cell number. | Circadian rhythmicity has been reported in various small intestinal digestive-absorptive functions and in the mitotic activity of intestinal crypt cells. These functional activity rhythms and perhaps the mitotic rhythms are cued by the feeding schedule. We now report that circadian rhythms also occurred in both the vil... | 437,929 | [
0.009887327,
-0.1148022,
-0.3836231,
0.03370148,
0.2374239,
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0.09567858,
0.1423275,
0.2086927,
0.1732865,
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-0.09300232,
0.02573337,
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0.193902,
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0.1268427,
-0.1179052,
0.1465021,
... |
Circadian rhythm of cholesterol biosynthesis: dietary regulation in the liver and small intestine of hamsters. | Sixty three hamsters were divided into two groups which were exposed to the same rigid lighting schedule (06(00)--18(00)) but fed at different time intervals (18(00)--22(00), and 08(00)--12(00), respectively) for five weeks. The cholesterol synthetic activity was then determined in liver, gastrointestinal tract, and ki... | 437,931 | [
-0.0378702,
0.25742,
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-0.003203199,
0.1135972,
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0.2789477,
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-0.08699057,
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0.1460911,
0.1028831,
0.2631876,
-0.1186069,
... |
The theory of social services in disaccumulationist capitalism. | The theory of social services today must be based on a more general theory of the "disaccumulation" of capitalist society. Capitalist society disaccumulates as new productive forces emerge within the framework of the capitalist labor market. These forces are expressed abstractly in new sources of productivity based on ... | 437,937 | [
-0.2670049,
0.1431438,
0.2583681,
0.02878243,
0.3336865,
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0.08655756,
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0.07929453,
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-0.06827503,
-0.1328848,
0.1540911,
-0.27942,
0.06603678,
0.4142015,
-0.1540557,
... |
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