title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Side-chain monofluorinated analogs of amphetamine and p-chloroamphetamine. Effects on release of dopamine and 5-hydroxytryptamine from rat striatum. | Monofluorinated analogs of (+/-)-amphetamine and (+/-)-p-chloroamphetamine, in which the methyl group was replaced with a monofluoromethyl group, have pKa values approximately 1.65 units lower than those of their amphetamine counter-parts but retain some ability to stimulate release of dopamine and 5-hydroxytryptamine,... | 432,436 | [
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Pharmacokinetics of verapamil in man. | Verapamil was given intravenously (10 mg) and orally (120 mg) in six healthy subjects. After intravenous administration, the serum levels in all subjects declined bi-exponentially. Thereupon, pharmacokinetic parameters were calculated using a two-compartment open model. The half-lives of distribution (T 1/2 alpha) and ... | 432,439 | [
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[Phantom substances for the simulation of tissue of the soft parts in ultrasonic diagnostics (author's transl)]. | The image-transmitting methods using ultrasound are gaining ground in medicine and are being increasingly used alongside the methods of diagnosis based on x-ray film. Whereas the use of phantoms for purposes of measurement and instruction has been common for a long time, there have so far been hardly any suitable phant... | 432,482 | [
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[Explatory roentgen examination of the anal canal (author's transl)]. | Endoscopy is supplemented by a roentgenographic exploration of the anal canal via single and double-contrast methods, as part of routine irrigoscopy. A brief description is given of the technique employed in the examination of 256 patients. Normal roentgen anatomy is described in detail, followed by a definition of the... | 432,485 | [
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[Exceptional diabetic arthropathy of the foot (author's transl)]. | The osteopathy of the foot is a rare complication of diabetes mellitus. It is seen in the distal parts mostly. The arthropathy ("Charcot-joint") is even more rare, and is regularly combined with a neuropathy. The roentgen signs of the "diabetic foot" are demonstrated, as there are osteoporosis, iuxta-articular cortical... | 432,486 | [
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Transient right bundle branch block during His bundle electrogram in a case with ventricular parasystole. | A case with ventricular parasystole and transient right bundle branch block during His bundle electrogram is reported. Although on surface electrocardiogram no preexisting atrioventricular (A--V) conduction disturbances could be noted, His bundle electrogram showed latent infrahisian conduction changes. This suggests a... | 432,503 | [
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Radioimmunoassay of group I pepsinogens (PGI) and the effect of food on serum PGI. | A sensitive and precise radioimmunoassay of group I pepsinogens (PGI) in serum is described. The method is a modification of the one described by Samloff and Liebman. The most important improvement is that 125I-labeled PGI can be stored diluted for at least 7 weeks without loss of immunoreactivity. The present method h... | 432,546 | [
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Lymphocyte studies in rheumatoid arthritis. III. A comparative study of the responses of peripheral blood and synovial fluid lymphocytes to phytomitogens. | The response of peripheral blood and synovial fluid lymphocytes to three non-specific mitogens has been studied. The paired samples were taken from patients with a range of inflammatory arthritides. Unstimulated synovial fluid lymphocytes (SFL) tended to have a greater uptake of tritiated thymidine than had unstimulate... | 432,557 | [
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[Isoelectric electroencephalography approximately 6 hours after ventricular fibrillation due to myocardial infarct. Apropos of a case with favorable development]. | A 59-year-old patient was resuscitated after ventricular fibrillation due to anterior myocardial infarction. Ventilatory and cardiac arrest lasted for more than 20 minutes. 5 h 50 min later the EEG was isoelectric. The evolution was nevertheless favourable and the patient was able to leave hospital one month later and ... | 432,585 | [
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[Essential bone cyst and its therapy]. | Twenty-nine cases of unicameral bone cyst treated surgically are reported. The literature is reviewed and different methods of treatment are discussed. Important factors contributory to the risk of recurrence are identified and stressed. | 432,602 | [
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[The primary ovarian carcinoid. Case report]. | A rare primary carcinoid tumor of the ovary, found incidentally in a 68-year-old woman, is reported. There had been no symptoms of carcinoid syndrome. Grossly, the unilateral tumor was cystic, measuring 13 cm in greatest diameter. Microscopically it consisted mainly of solid epithelial cords. The demonstration of argen... | 432,604 | [
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[The hand in diabetes. Study of 97 diabetics compared to a control group]. | To determine whether there is hand involvement specific to diabetes, 97 diabetics were compared with the same number of matched controls. Hands were examined with particular emphasis on skin, intrinsic muscles, articular mobility, sense of touch and vibration, digital systolic pressure, and radiological analysis of bon... | 432,605 | [
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Studies on purification of oestrogen-induced protein from rat uterus and its physiological role in cultured cells. | This paper presents evidence to show the presence of an oestrogen-induced protein (IP) from rat uterus which is able to stimulate the incorporation of 3H-thymidine into DNA of 3T6 fibroblasts in vitro. The purified uterine protein fraction has been shown th contain less than 10 detectable proteins. The molecular weight... | 432,624 | [
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Anomalous amide I infrared absorption of purple membrane. | Infrared absorption of purple membrane reveals an amide I frequency that falls outside the range normally found for alpha helices. This may indicate along with x-ray diffraction the existence of bacteriorhodopsin alpha helices with unusual structure. | 432,645 | [
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Clomid administration to pregnant rats causes abnormalities of the reproductive tract in offspring and mothers. | In rats, a single injection of clomiphene citrate (Clomid) during pregnancy causes multiple abnormalities of the reproductive tract in the offspring and mothers. These abnormalities probably result from the ability of Clomid to cause long-term estrogenic stimulation. | 432,668 | [
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Respiratory failure secondary to Mycoplasma pneumoniae infection. | Three previously healthy patients presented with bilateral pulmonary infiltrates, hypoxemia, and respiratory failure associated with Mycoplasma pneumoniae infection. None had underlying pulmonary or immune deficiency diseases. One died with dense fibrotic reorganization of the lungs, and another survived after prolonge... | 432,684 | [
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Pulmonary infection with Petriellidium boydii. | A 52-year-old woman with pulmonary involvement with Petriellidium boydii in a bronchiectatic lung segment is described. Pulmonary involvement with this organism has been most frequently described in patients with underlying systemic diseases or compromised immune systems. This patient apparently had neither problem and... | 432,688 | [
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Mechanical properties of human lumbar spine motion segments. Influence of age, sex, disc level, and degeneration. | The influences of age, sex, disc level, and degree of degenration on the mechanical behavior of 42 fresh cadaver lumbar motion segments are reported. The motions and intradiscal pressure changes that result from the application of flexion, extension, lateral bending, and torsional moments; compression; and anterior, po... | 432,710 | [
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Neurologic recovery of paraplegia following use of salmon calcitonin in a patient with Paget's disease of spine. | A case report of spastic paraparesis due to Paget's disease of the dorsal spine is presented. The patient became almost completely paralyzed in the lower limbs in spite of a decompressive laminectomy. He was treated with salmon calcitonin with very rapid neurologic recovery. The limits of the regimen and possible compl... | 432,714 | [
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The problem of the cystic duct remnant. | Symptoms persisting after cholecystectomy for gallbladder disease are often attributed to a long residual cystic duct. Of 30 patients who underwent excision of their cystic duct remnant, 15 were found to have common duct stones which accounted for their symptoms, while an additional four patients had had previous episo... | 432,764 | [
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Experimental and clinical hepatorenal bypass as a means of revascularization of the right renal artery. | In patients with severe atherosclerosis of the abdominal aorta or previous operations on the abdominal aorta, right renal revascularization may be difficult to achieve using aortorenal bypass. An experimental study was performed demonstrating the efficacy of hepatorenal bypass as an alternative operative procedure in t... | 432,770 | [
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In vivo use of human umbilical vessels and the ductus venosus arantii. | Clinical use of umbilical vessels in the neonate is commonplace. In the adult, surgical reopening of the umbilical vein is feasible in the majority of patients, providing direct access to the portal circulation. Umbilical vein catheterization allows for portal manometry in the intact, unanesthetized state. Prolonged ca... | 432,777 | [
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Experimental and clinical postnatal craniofacial skeletal changes. | An understanding of normal and abnormal postnatal skeletal changes can aid in the prevention, early recognition and proper surgical treatment of craniofacial deformities. Research findings may have important implications and applications in relation not only to the basic problem of change of bone form but also to the c... | 432,778 | [
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The effects of the concentration and function of hemoglobin on the survival of rats after hemorrhage. | Hemodilutional techniques of resuscitation, which are becoming popular, add anemia to the acute increase in the affinity of hemoglobin for oxygen that occurs in massively transfused patients when old liquid stored blood is used. A model simulating these conditions was established in rats, using blood stored in citrate ... | 432,803 | [
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Gardner's syndrome complicated by mesenteric desmoid tumors. | Mesenteric desmoid tumors present difficult management problems among patients with Gardner's syndrome. Appearance of the problem is associated with prior abdominal surgery and with pregnancy. In the authors' experience, radical surgery alone has failed to control the disease and they recommend that it should be avoide... | 432,809 | [
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Perilobular fibrosis in chronic bovine fascioliasis. | The character, extent, and localization of perilobular fibrosis were studied in cattle experimentally infected with Fasciola hepatica. Such fibrosis is indirectly due to the liver flukes. The regionally localized fibrosis results from cholestasis due to transient occlusion of branches of the biliary tree. In periobular... | 432,878 | [
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[Diagnosis of tumors of the parotid gland by sialography and saialoscintigraphy. A comparative study on 49 patients (author's transl)]. | 169 patients with different diseases of the salivary glands were examined by means of sialography and sialoscintigraphy. The results of these examinations were analysed by a blindfold test. The sialographic diagnosis was correct for 47 of 49 tumors checked by histologic examinations. There is no specific criterium for ... | 432,889 | [
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Platelet behavior in extracorporeal circulation (ECC). | Compatibility of blood with nonphysiologic materials is of increasing importance. The basis of estimating such compatibility has shifted from the determination of hemolysis to the estimation of the clotting capacity. This can be specified in terms of number and function of curculating thrombocytes and the resulting ble... | 432,915 | [
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Plasma adenine and cellular ATP in red cell concentrates collected and stored in modified CPD at 4 C. | Eight units of blood were drawn into modified CPD containing 25 per cent higher glucose and 17.3 mg adenine (0.25 mM in blood). Red blood cell concentrates (RCC) were prepared to a mean hematocrit (Hct) of 70, the cells stored at 4 C, and plasma adenine and red blood cell adenosine triphosphate (ATP) were measured week... | 432,914 | [
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0.110985,
0.4079701,
0.1469447,
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0... |
[Effect of glycerin and urea on rat skeletal muscle twitches]. | The dynamics of changes in the amplitude of isometric twitches of isolated EDL and SOL muscles of young rats influenced by low molecular non-electrolytes has been studied. Incubation of EDL in hypertonic glycerol or urea solution (400 mM) leads to a 80 and 60% decrease of twitches, respectively, within 15 minutes. Duri... | 432,956 | [
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0.04269435,
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0.03708352,
0.09111632,
0.118755,
-0.004793... |
[Ultrastructure of goose intestinal epithelial cells infected with Eimeria kotlani]. | The ultrastructure of goose intestinal epithelial cells infected with various stages of E. kotlani has been described. No changes in the ultrastructure of the nucleus and cytoplasm were detected in cells, containing asexual stages. Damage of host cell structures, except Golgi complex, was not observed until gamogenesis... | 432,966 | [
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0.2163277,
0.1441471,
0.1011215,
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0.240959,
0.06796922,... |
Fibrous contracture of bladder neck: cause, prevention, and treatment. | Through a retrospective study of bladder neck contracture it was found that bladder neck resection and incision were equally effective for treatment of postoperative bladder neck contractures. It was also found that incising the bladder neck at the end of transurethral resection of the prostate (TURP) did not cause ves... | 433,044 | [
0.2755481,
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0.1161166,
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0.07573025,
0.06589374,
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Gray scale ultrasound in identification of lymphoma complicating lymphomatoid granulomatosis. | Lymphomatoid granulomatosis is a necrotizing vasculitis involving multiple organs which may be associated with lymphomatous transformation. A case of lymphomatoid granulomatosis is presented in which gray scale ultrasound identified lymphomatous transformation involving the right kidney and retroperitoneum, thus preven... | 433,061 | [
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0.2754551,
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0.4572233,
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0.116182,
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[Problems in the surgical treatment of the thromboembolic complications of rheumatism]. | After having studied the results of the surgical and conservative treatment in thromboses and emboli of the aorta and main arteries of the limbs in 32 patients with rheumatism the authors note a high percentage of mortality and postoperative complications. A valuable intense antirheumatic therapy, complex of measures c... | 433,089 | [
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0.2648928,
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0.4578751,
0.3964862,
0.02865813,
-0... |
[Skin reactions of delayed hypersensitivity in melanoblastoma]. | Cell factors of nonspecific immunity were estimated in 99 patients with different stages of melanoblastoma by delayed hypersensitivity skin test to tuberculin and DNCB (2,4-dinitrochlorobenzene). The skin test to DNCB is found to correlate with the clinical manifestations of the disease, while the skin test to tubercul... | 433,214 | [
-0.1100562,
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0.2830245,
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0.01246558,
0.4295589,
0.4600803,
-0.06116797,
-0.06730387,
... |
[Breast cancer in combination with other malignant tumors]. | Since 1950 to 1968 in the Nikolaevsk Province Oncological dispensary 1006 breast cancer patients were radically operated upon. 943 patients were followed up, primary multiple tumors being observed in 52 of them (5.5%). Primary multiple tumors in stage I were noted in 2.3% of cases, in stage II--in 7.7%, in stage III--i... | 433,218 | [
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0.4319214,
0.002783052,
0.5613064,
0.2007367,
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0.54... |
[Repeated operations in pancreatic cancer]. | Twenty four reoperations were performed for cancer of the pancreas. The indications were as follows: gastroduodenal obstruction, recurrent jaundice, external biliary fistulas and uneffective primary operations. In 20 patients palliative measures were performed, which improved considerably the patents' state. Reoperatio... | 433,221 | [
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0.09192242,
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0.08697738,
0.03545375,
0.08298... |
[B group and ascorbic acid vitamin allowance of the therapeutic rations of phenylketonuria patients]. | The allowance of the vitamin group B and ascorbic acid in specialized rations for children suffering from phenylketonuria was studied. A significant deficiency in a number of the study vitamins (thiamine, riboflavin, pyridoxine, niacin, ascorbic acid) was detected, this being confirmed by the excretary findings. Inclus... | 433,228 | [
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0.207164,
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0.3598306,
0.2402368,
0.1216502,
0.0727015... |
[Bicycle spoke injuries in children (author's transl)]. | 140 typical bicycle spoke injuries in children were seen during two years in the Pediatric Surgical Hospital of the University of Graz (Austria). 15% of the patients had bone fractures. In order to prevent such accidents satisfactory child seats, special foot supports and protective canvas over the upper half of the wh... | 433,294 | [
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0.396532,
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-0.01324032... |
Metabolism of chlorodiphenyl ethers and Irgasan DP 300. | 1. In the rat chlorodiphenyl ethers are metabolized via two routes. The predominant reaction is aromatic hydroxylation; scission of the ether bond is a minor metabolic process. 2. In all cases, primary hydroxylation takes place ortho and meta to the ether bond. Ortho-hydroxylation leads to the formation of 'predioxins'... | 433,312 | [
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0.1243114,
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0.4235125,
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... |
[Contribution to aetiology by the primary pulmonary sarcoma in comparison to the pulmonary carcinoma (author's transl)]. | On 41 primary pulmonary sarcomas in the years 1957 till 1974 and on 192 pulmonary carcinomas in the year 1969 cancerogene noxes and endogene factors were analysed, compared and discussed with literature. Smoking of cigarettes, chronic bronchitis and radioactive radiation at underground mining are also significantly acc... | 433,329 | [
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0.2548089,
0.3196152,
0.4070098,
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-0... |
[Small bowel biopsy as a cause of pseudomonas aeruginosa septicemia in a patient with intestinal lymphoma? (author's transl)]. | A patient with intestinal lymphoma developed a gram-negative septicemia 48 hours following a peroral biopsy of the small intestine. The bacteriological examination of the instrument proved the same bacteria (Pseudomonas aeruginosa) which was the cause of septicemia. On the basis of our observation and of other reports ... | 433,373 | [
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0.1020399,
0.02472205,
0.1649857,
0.1666331,
0.1338771,
-0.013681... |
[Interaction of the somatosensory and auditory systems in awake cats at the level of the cortical projection zones]. | A comparative study of somato-acoustic interactions has been brought out by EP method in the auditory area A1 several projection areas of S1 and in S2 of non-immobilized cats with chronically implanted electrodes. Single cutaneous stimulation of the contralateral fore-leg with an intensity equal to 1.5 to 3 thresholds ... | 433,433 | [
-0.04981465,
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0.047077,
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0.01541877,
0.0130779,
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0.04297799... |
[Textile fibres under the prepuce--criminalistic proof for a sexual assault (author's transl)]. | 1. One day after a sexual assault the male suspect was investigated by a physician who found yellow textile fibres on his penis. 2. The police secured yellow fibres from the bed-cover, the socks and the panties of the victim. 3. At the laboratory the four kinds of fibres were analyzed. The fibres from the bed and the p... | 433,457 | [
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0.1273809,
0.05319903,
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0.2874359,
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-0.005527771,... |
The significance of drug analysis of sweat in respect to rapid screening for drug abuse. | Morphine and methamphetamine, which are excreted in the sweat, are detected by the use of routine serological and physicochemical techniques for urinary examinations. Screening for drug abuse can be done with the same accuracy of that of urine. Rapid excretion of the drug via kidney (within one day) is followed by a sl... | 433,459 | [
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0.2224346,
0.212033,
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0.1224174,
-0.06... |
[Bronchial carcinoma; late results (author's transl)]. | In the last 20 years 482 patients underwent surgery for bronchial carcinoma: mortality rate 5,8%. Pneumonectomy was performed in 172--, bilobectomy in 24--, lobectomiy in 254-- and segmental resection in 32 patients. 5 year survival rate is 36,0%. The late results depend on the size of the tumour, presence or absence o... | 433,486 | [
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0.2949234,
0.2943664,
0.6661792,
0.02169402,
0.07175149,
... |
[Dislocation of the os lunatum and associated injuries (author's transl)]. | 234 cases of dislocation of the lunate and its associated injuries taken from literature are statistically examined. The outcome shows that the number of false diagnoses is still high. With immediate reduction the late results are good, whereas the treatment of old dislocations is not satisfactory. | 433,488 | [
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0.04851273,
-0.1626288,... |
[Disease of metalgrinding workers (author's transl)]. | It is a specific clinical picture with extensive soft tissue gas and swelling of the forearm. Usually, the clinical course is without any other symptoms. Therapy is not necessary because gas disappears in few days. The etiology of the disease is not clear. Gas can be generated by the chemical reaction between a metalli... | 433,489 | [
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0.3078447,
0.1186854,
0.2963375,
-0.02100... |
Non-operative management of splenic rupture. | A splenectomized patient is at a significant increased risk of serious infection. Consequently, it is mandatory to avoid splenectomy whenever possible. In selective trauma cases this is feasible, either by surgical repair of the ruptured spleen or by non-operative management. Nine typical cases of splenic rupture diagn... | 433,516 | [
-0.2246875,
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0.02605763,
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Changes in laser-irradiated retina in the first 24 h after irradiation. | Retinas of laser-irradiated mice were studied in the first 24 h after irradiation. Decrease in Na+ and K+ concentrations and in phagosome number and increase in pyknotic cells were observed several hours after irradiation. | 433,565 | [
-0.04587003,
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0.1426982,
0.4148158,
0.2109731,
0.1330543,
... |
Total hip replacement in juvenile rheumatoid arthritis. Analysis of 59 hips. | The results of 59 Charnley low friction arthroplasties in 41 patients with juvenile rheumatoid arthritis are presented. Mean follow-up was 30 months and mean age at operation 30.5 years. At review 90 per cent had an excellent result and 10 per cent a good result as regards pain relief. Mobility was significantly improv... | 433,583 | [
0.04650266,
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0.1359307,
0.02602084,
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0.2475718,
0.05465531,
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Quantitative evaluation of hypertensive pulmonary arterial change. | A new method to quantitatively evaluate pulmonary arterial change in pulmonary hypertension is presented in this paper. Hypertensive pulmonary arterial changes are classified into four grades according to severity and a score from 1 to 4 is given to each arterial change according to the grading. An index of pulmonary v... | 433,591 | [
-0.0734922,
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Modulation by macrophages of lymphocyte responses to phytohaemagglutinin, concanavalin A and semiallogeneic cells. | To investigate the effect of macrophages on rat lymphocyte activation by phytohaemagglutinin (PHA), concanavalin A (Con A) and semiallogeneic cells (uniderectional MLR), increasing concentrations of peritoneal cells (PC) were added to cultures of lymph node lymphocytes. Lymph node cell preparations contained 2-4% ester... | 433,602 | [
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0.1535167,
... |
Precipitating antibodies in dermatophytosis demonstrated by crossed immunoelectrophoresis. | A total of 289 serum specimens from 262 patients with dermatophytosis were studied, using crossed immunoelectrophoresis with an intermediate gel. Rabbit antidermatophyte antisera were used as reference, and the antigens were water soluble extracts of Trichophyton (T) rubrum, T. mentagrophytes, Microsporum (M.) canis or... | 433,603 | [
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0.47284,
0.2622947,
-0.2698585,
... |
The timing of the immune response in relation to virus growth determines the outcome of the LCM infection. | In the present study earlier observations of a dual role of the immune response against lymphocytic choriomeningitis (LCM) virus were confirmed and extended. At different times after intracerebral (i.c.) inoculation of the virus, groups of immunosuppressed recipients were transplanted with primary effector cells or mem... | 433,605 | [
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0.3820755,
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... |
Effects of the GABA receptor agonist muscimol on the turnover of brain dopamine and on the motor activity of rats. | Muscimol (3-hydroxy-5-aminomethylisoxazole) at a high dose (10 mg/kg intraperitoneally) elevated the concentration of brain dopamine in rats, decreased the utilization of dopamine and increased the synthesis of dopamine. The utilization of noradrenaline was acclerated rather than retarded by muscimol. Local application... | 433,609 | [
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0.1448108,
... |
Inhibition of ATP-induced contraction in the guinea-pig urinary bladder in vitro and in vivo. | Contractions were elicted by adenosine 5'-triphosphate (ATP) in the guinea-pig urinary bladder in vitro and in vivo. In isolated detrusor strips, tetrodotoxin (3.1 x 10(-6)--4.4 x 10(-5) M) did not affect contractions induced by a submaximum concentration (10(-3) M) of ATP, nor did atropine (1.7 X 10(-6)--2.1 x 10(-4) ... | 433,613 | [
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... |
Lithium treatment and glucose tolerance in manic-melancholic patients. | Intravenous glucose tolerance was measured in manic-melancholic patients given one daily lithium-dose for relapse prevention. It was found that glucose tolerance was increased for some hours after each lithium administration. In the first week of treatment glucose disposal rate was increased up to 12 h after lithium in... | 433,629 | [
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Mortality in psychiatric hospitals in Norway 1950--74. | The present investigation comprises all deaths in Norwegian psychiatric hospitals 1950--74: 10,413 deaths. Mortality in men declined from 361 per 10,000 before 1950 to 252 per 10,000 in 1969--74 and in women from 324 per 10,000 to 215 per 10,000 during the same periods. In the organic and symptomatic psychoses (mainly ... | 433,634 | [
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The 'sprained wrist'. | "Sprain of the wrist" is a precarious diagnosis. Although true ligamentous injuries do occur, it is important for the physician who first sees the patient to make a more specific and accurate diagnosis. In most instances, this can be done by locating the precise area of maximum tenderness and obtaining appropriate radi... | 433,714 | [
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0... |
The single precordial lead for ST segment monitoring: comparison with the multiple lead map. | ST segment elevation, used as an index of the relative extent of myocardial ischemic injury, was measured using a single precordial lead located at the point of maximum ST elevation. ST changes were followed for two hours after acute coronary occlusion in pigs, and were compared to the sum of ST elevation recorded with... | 433,752 | [
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Effect of isosorbide dinitrate on response to submaximal and maximal exercise in patients with congestive heart failure. | Isosorbide dinitrate is an effective vasodilator that improves resting left ventricular performance in patients with congestive heart failure, but little is known of the effect of the drug on the response to exercise. Bicycle exercise to symptomatic maximum was performed by 18 patients with class II to IV congestive he... | 433,762 | [
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Disopyramide-induced ventricular fibrillation. | Three cases are described with documented ventricular fibrillation shortly after the patients received disopyramide in moderate dosage. Electrocardiograms showed markedly prolonged Q-T intervals in two patients and a prominent U wave with a prolonged Q-U interval in one patient, but no change in QRS width. Disopyramide... | 433,766 | [
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Unusual vascular anomalies causing persistent pulmonary hypertension in a newborn. | A unique case of pulmonary vascular anomalies causing persistent pulmonary hypertension in a newborn is described. The child died 3 days after birth. Necropsy revealed marked hypoplasia of the right and left pulmonary arteries with a normal main pulmonary artery, patent ductus arteriosus, bilateral systemic arteries to... | 433,778 | [
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Monitoring ventricular function at rest and during exercise with a nonimaging nuclear detector. | A portable nonimaging device, the nuclear stethoscope, for measuring beat to beat ventricular time-activity curves in normal people and patients with heart disease, both at rest and during exercise, is being developed and evaluated. The latest device has several operating modes that facilitate left ventricular and back... | 433,780 | [
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Effects of digoxin on sinus nodal function before and after vagal blockade in patients with sinus nodal dysfunction: a clue to the mechanisms of the action of digitalis on the sinus node. | To increase the limited knowledge of the effects of digitalis on sinus nodal function in patients with sinus nodal dysfunction and to initiate an investigation into the mechanisms underlying its effects, 34 patients with sinus nodal dysfunction were studied. Twenty patients underwent determination of sinus cycle length... | 433,782 | [
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Functional heterogeneity in a multipinnate muscle. | Many mammalian muscles have a complex internal architecture. This type of structure could allow a single muscle to produce a variety of force vectors through selective regional contractions. This hypothesis was tested electromyographically in the multipinnate pig masseter by recording simultaneously from several intram... | 433,798 | [
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Total free amino acids, ammonia, and protein in the sweat of children. | The concentrations of total free amino acids, ammonia and protein in sweat of 44 children, 20 males, and 24 females, 6 to 8 years old, were determined. The children were divided into three groups according to their height, weight, and body weight/height ratio; group I children had heights and weights below the 10th per... | 433,807 | [
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Functional assessment of nutritional status: heart rate response to submaximal work. | The heart rate response to submaximal treadmill work been calculated using the heart rates and oxygen intakes obtained from normally nourished and undernourished adult male subjects during a maximal oxygen consumption test. Increased severity of malnutrition was associated with an increased heart rate response to the s... | 433,809 | [
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Zinc retention and losses of zinc in sweat by preadolescent girls. | Preadolescent girls, ages 7 to 9 years, were fed levels of zinc ranging from 5.61 to 14.61 mg/day during an 18-day metabolic study. All other nutrients were provided at or above Recommended Dietary Allowance levels. The sweat loss of zinc was measured using an arm-bag method and whole body zinc loss was calculated from... | 433,811 | [
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4q- syndrome. | To our knowledge, there have been three prior reports of patients found, with trypsin-Giemsa banding, to be monosomic for the terminal q segment of chromosome 4. Described herein is a fourth patient with this chromosome abnormality. Comparison of these four patients suggests a characteristic phenotype in the 4q- syndro... | 433,854 | [
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... |
Ultrasound in the diagnosis of cholestatic jaundice. | A total of 70 cases of cholestatic jaundice have been studied by gray scale ultrasonography in order to evaluate how this technic may be used to differentiate between intra- and extrahepatic cholestasis. In 37 out of 42 patients (88.1%) with jaundice of extrahepatic origin, dilatation of the biliary tree was demonstrat... | 433,899 | [
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Idiopathic calcific pancreatitis, CRST syndrome and progressive systemic sclerosis. | A 43-year old man with CRST syndrome (calcinosis, Raynaud's phenomenon, sclerodactyly and telangiectasia) and progressive systemic sclerosis presented with a four-year history of relapsing abdominal pain, the result of chronic pancreatitis, not associated with alcoholism, biliary disease, or any of the known causes of ... | 433,900 | [
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Colonic intussusception in uremia. | Colonic intussusception is a condition primarily found in infants and young children. In adults, it is usually associated with a colonic neoplasm. The following report illustrates a case of colonic intussusception in an adult uremic patient in whom postmortem examination showed evidence only of intramural colonic hemor... | 433,910 | [
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The UCLA population studies of chronic obstructive respiratory disease. I. Methodology and comparison of lung function in areas of high and low pollution. | The prevalence of symptoms of chronic obstructive respiratory disease and of functional respiratory impairment was determined in 3465 residents (70 per cent of enumerated) of an area historically exposed to photochemical/oxidant pollutants and 4509 residents (79 per cent of enumerated) of an area exposed to low levels ... | 433,916 | [
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Pericardial disease in rheumatoid arthritis. | Six patients with rheumatoid constrictive pericarditis, five seen in a two and one half year period, are described. All patients were male, all had rheumatoid factor, and all had active arthritis. Diagnosis was suspected from careful physical examination and confirmed in five patients by cardiac catheterization. Perica... | 433,944 | [
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0.0668823... |
Human fetal breathing activity during electively induced labor at term. | Human fetal breathing movements were measured during the first stage of electively induced labor in 20 healthy term pregnancies. Fetuses made breathing movements 25.6% of the time during a 1 hour control period and breathing decreased significantly to 8.3% during latent-phase labor and further decreased to 0.8% during ... | 433,983 | [
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The clinical prediction of intrauterine growth retardation. | From a total study group of 8,030 deliveries, 2,788 patients with risk factors and 292 representative patients from the 5,242 patients without risk factors were selected for detailed analysis of predictors of intrauterine growth retardation (IUGR). Two thirds of the IUGR infants came from the population with risk facto... | 433,988 | [
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Marlex gauze hammock sling operation with Cooper's ligament attachment in the management of recurrent urinary stress incontinence. | In 1970 Morgan described an operation designed to meet the problem created by scarring and fibrosis resulting from previous operative procedures to the urethra and bladder neck. In the method, a 2 cm wide polypropylene (Marlex) mesh is placed as a broad hammock to elevate and support the urethrovesical junction with la... | 433,990 | [
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Remission of uterine leiomyosarcomas treated with vincristine, Adriamycin, and dimethyl-triazeno-imidazole carboximide. | Six patients with metastatic uterine leiomyosarcoma have been treated with the combination of vincristine, Adriamycin, and DTIC. Complete remissions were obtained in three patients and a partial remission in a fourth. The average duration of response was 15.6 months and one patient is free of disease at 24 months. Seve... | 433,999 | [
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... |
Further evidence for the role of prolactin on human fetoplacental osmoregulation. | The addition of ovine prolactin (oPRL) to the fetal side of human term amnion in vitro is associated with a decrease in membrane permeability to tritiated water (THO). As the concentration of oPRL is increased from 2.5 to 20.0 micrograms per milliliter, permeability is progressively impaired. The addition of a specific... | 434,010 | [
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Meperidine and normeperidine levels following meperidine administration during labor. I. Mother. | Because of the unavailability of sensitive analytic techniques, the pharmacokinetics of meperidine have not been clearly delineated in obstetric patients during labor. Moreover, the production of the active meperidine metabolite--normeperidine--has not been investigated. By means of gas chromatographic and mass spectro... | 434,034 | [
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Exacerbation of senile macular degeneration following cataract extraction. | Six eyes in four patients had hemorrhagic detachment of the retinal pigment epithelium following cataract extraction. All eyes had evidence of nonexudative senile macular degeneration preoperatively as manifested by drusen or alterations in the retinal pigment epithelium, or both. Postoperatively, all eyes had evidence... | 434,056 | [
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Opticociliary veins in a primary optic nerve sheath meningioma. | A 59-year-old man developed painless visual loss in his left eye over a one-year period, with rapid progression to blindness over three months. Ocular examination of the left eye revealed proptosis, marked optic disk pallor, dilated retinal veins, and congeries of vessels at the disk margin (opticociliary veins). His r... | 434,059 | [
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0.01312547,
... |
Familial exudative vitreoretinopathy. | At age 26 years a woman who had been blind in the left eye from birth had visual acuity of R.E.: 6/18 (20/60); L.E.: 6/120 (20/400), with 40 prism diopters of left exotropia. The left eye showed a decreased anteroposterior diameter of the globe and a complete retinal detachment behind a cataractous lens. The right eye ... | 434,067 | [
-0.2409019,
0.02194717,
-0.02331157,
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0.1697119,
0.01320214,
-0.5001819,
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0.3155109,
-0.1075102,
... |
Anterior polar cataracts associated with bilateral retinoblastoma. | A 13-month-old girl had bilateral congenital cataracts at four days after birth. At age 4 months the cataract in her right eye was observed by her mother to enlarge and change in color. Examination of the fundus disclosed a large yellow mass. The eye was subsequently enucleated and histopathology confirmed the diagnosi... | 434,085 | [
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0.2678513,
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0.2786601,
0.2588036,
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0.1798... |
Clinical evaluation of an inexpensive ultrasound oculometer for ocular biometry. | We measured anterior chamber depth and axial length in 200 human eyes with the Echo-Oculometer and the Digital Biometric Ruler. There was good agreement between measurements with the two instruments. The echo-Oculometer is much less expensive than any other instrument available for measuring ocular axial length and sat... | 434,088 | [
-0.06756147,
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Role of endothelium and hypercholesterolemia in intimal thickening and lipid accumulation. | In experiments reported here we tested the hypothesis that persistent absence of endothelium favors intimal thickening, lipid accumulation, and atherosclerosis. Rabbit aortas were de-endothelialized with a balloon catheter at Day 0. Initially, all rabbits were fed a diet low in lipid. Some rabbits (Group I) were contin... | 434,106 | [
0.007450088,
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0.04260705,
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0.5063919,
0.02481802,
... |
Absence of neutral protease and alkaline phosphatase in neutrophils of a case of hairy cell leukemia. | Enzymaticaly homogeneous fractions of lymphocytes, monocytes, and neutrophils were isolated by zonal centrifugation from peripheral blood of a patient with hairy cell leukemia, or leukemic reticuloendotheliosis, LRE,(with leukopenia, neutropenia, lymphocytosis, and massive splenomegaly). To detect enzymatic deficiencie... | 434,113 | [
0.08671166,
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0.0008361411,
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0.00508307,
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0.2150789,
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0.3198653,
-0.208449... |
Differential effects of television programming on preschoolers' cognition, imagination, and social play. | Three groups of preschoolers were exposed over two weeks to daily programs of Misterogers Neighborhood, Sesame Street, or a control series of nature and animal films. Specific hypotheses about the effects of program format upon recall of content and upon subsequent behavior were tested. The apparently more slow-paced f... | 434,121 | [
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0.1455196,
0.08825251,
0.2742576,
0.207948,
0.08353... |
Shared parenting after separation and divorce: a study of joint custody. | Intensive case studies of four families in which divorced parents have maintained joint custody of their children suggest that this arrangement works well under certain conditions. Components of a successful joint custody arrangement are considered, limitations are discussed, and support is urged for divorcing parents ... | 434,126 | [
-0.2954186,
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0.3295577,
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0.01103795,
0.1812346,
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0.14793... |
EMG comparison of quadriceps femoris activity during knee extension and straight leg raises. | Both knee extension and straight leg raises have been used to rehabilitate atrophied quadriceps musculature following knee immobilization. A comparison of the tension developed during these two exercises was made in each of the three surface quadriceps muscles (quadriceps femoris, vastus lateralis, vastus medialis) at ... | 434,132 | [
-0.358632,
0.180333,
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0.1373646,
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0.2266531,
-0.1939401,
0.2746311,... |
Measurement of myocardial PCO2 with a microelectrode: its relation to coronary sinus PCO2. | A micro-PCO2 electrode, with dimensions of 1 x 10 mm, and a 63% response time of 14 s was inserted into the left ventricular myocardium of the pentobarbital-anesthetized dog. Continuous recordings were made of myocardial PCO2 (PmCO2), arterial PCO2 (PaCO2), and coronary sinus PCO2 (CSPCO2) during variation of respirato... | 434,171 | [
-0.1899048,
0.1333463,
-0.2554726,
-0.04869495,
-0.1546571,
0.03603153,
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0.04214942,
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0.1474298,
0.06078121,
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0.03095342,
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0.1510178,
0.1402987,
0.08284396,
0.01214487,
-0.05171279,
0.4348771... |
Effect of estrogen on rate of 59Fe uptake by hemopoietic tissue in Japanese quail. | Injection of 2 mg estradiol valerate into male Japanese quail caused the rate of 59Fe uptake by the skeleton to drop 70% within 48 h. This phenomenon was due to an increase in the iron-binding capacity of the plasma induced by estrogen that caused a substantial decline in the availability of the label for hematopoiesis... | 434,196 | [
-0.3042195,
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0.1648699,
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-0.0680867,
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0.2254846,
0.001243881,
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0.01545441,
0.04788142,
0.4135982,
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0.0625003,
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0.3484487,
-0.08587169,
0.1966486,
0.1750471,
0.4255947,
-0.1321829,
... |
Microvascular responses to norepinephrine in renovascular and spontaneously hypertensive rats. | Closed-circuit television microscopy was used to quantitate the responses of in vivo small arteries (50-140 micrometer diam) and veins (95-265 micrometer) to topically applied norepinephrine in the cremaster muscle of four groups of urethan-chloralose anesthetized rats. The rat groups were: Sprague-Dawley control (SDC)... | 434,218 | [
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0.01300101,
0.1243965,
0.2533326,
0.2524026,
0.1110761,
0.06070412,
0.028... |
Awareness and disengagement in cancer patients. | The authors found that cancer patients (N = 44) did not differ from patients with other chronic illnesses (N = 27) with respect to awareness of their condition or ratings on an unobtrusive, nonverbal measure of disengagement. Cancer patients who were aware were more engaged than those who were not, but this was equally... | 434,237 | [
-0.2596208,
0.1117369,
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0.06924473,
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0.4097977,
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0.1499222,
-0.01985309,
0.1558082,
0.07852636,
0.04578649,
-0.08909337,... |
Characteristics and disposition of persons found not guilty by reason of insanity in New York State, 1971-1976. | In order to develop an empirical profile of persons acquitted by reason of insanity from which policy could be developed, the authors studied all acquittals in New York State from 1971-1976. During this period 196 men and 29 women were found not guilty by reason of insanity. In contrast to adults admitted to state corr... | 434,242 | [
-0.3167809,
-0.01126825,
-0.1511294,
0.142487,
0.2482402,
0.06956021,
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0.05601628,
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0.2030934,
0.02770253,
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0.1334759,
0.2250834,
0.09613606,
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0.1052196,
0.06281823,
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0.3440778,
-0.1008136,
... |
Psychiatry and the rhetoric of models. | The term "medical model" has been increasingly used in discussions about the future course of psychiatry. The author examines various types of models and suggests that "medical model" is a rhetorical device which tends to obscure many important issues. He suggests that psychiatry avoid overrestricting its area of exper... | 434,243 | [
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-0.1021264,
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0.0387546,
0.2413087,
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0.01577818,
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0.2685173,
0.1732574,
0.0691155,
0.3086692,
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0.2638966,
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0.1432768,
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0.03304559,
0.2341539,
-0.1335237,
-0.1888272,
-0... |
An attempt to objectify the therapeutic process: a working model. | On the basis of their observations in daily psychoanalytic work the authors developed five objective criteria for "bad" analytic hours. These criteria involve affect, intellectualization, isolation, lack of feedback, and dissatisfaction. The authors developed a formulation to help them preconsciously recognize the pres... | 434,250 | [
-0.2038018,
0.1536434,
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0.07174172,
0.2124906,
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0.035485,
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0.09260321,
0.152983,
0.2850971,
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... |
The community meeting: a comparative study. | In this study of two identical open wards, the author found that in ward 1's highly structured meetings a higher proportion of patients participated, and they distributed their participation in more direct proportion to the relative numbers of each present than in the open meetings on ward 2, where patients directed th... | 434,254 | [
-0.1235742,
0.32104,
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0.1747021,
-0.3240006,
0.2102146,
-0.008606235,
0.2125386,
0.1138032,
... |
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