title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Gnathostoma spinigerum from the cervix of a woman in Jakarta. | A male Gnathostoma spinigerum was removed from the cervix of a 29-year-old Jakarta resident who suffered from chronic cervicitis. The worm was 6.7 mm in length and had eight rows of spines on the cephalic bulb. This is the third case of gnathostomiasis reported from Indonesia. | 434,307 | [
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Giardiasis in infancy and childhood: a prospective study of 160 cases with comparison of quinacrine (Atabrine) and metronidazole (Flagyl). | The therapeutic effects of quinacrine (Atabrine) and metronidazole (Flagyl) were compared in a 3-year prospective study of 160 infants and children (86 boys and 74 girls ranging in age from 4.5 months to 13 years) with giardiasis. The most common symptom was recurrent abdominal pain. In each study group stool examinati... | 434,310 | [
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Comparison of four species of snails as potential decoys to intercept schistosome miracidia. | Preliminary studies have shown that various species of aquatic snails may be used as decoys or "sponges" to intercept schistosome miracidia, thereby preventing the miracidia from reaching the snails which normally serve as their intermediate host. In this study, four species of snails were evaluated as candidate decoys... | 434,319 | [
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Pyogenic osteomyelitis of axial bones following civilian gunshot wounds. | A series of forty-five patients with low velocity gunshot wounds to the spine and pelvis were followed up for at least eight weeks to determine the incidence of pyogenic osteomyelitis and the role of debridement and fragment removal in its prevention. Four cases of osteomyelitis were found, and although debridement was... | 434,334 | [
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Activity of antibiotics in contaminated wounds containing clay soil. | Most traumatic wounds are contaminated to some degree by soil and run a high risk of infection. The presence of soil in wounds interferes with natural tissue defenses, which include phagocytosis and serum bactericidal capacity. The experimental studies reported herein clearly demonstrate that soil also limits the antib... | 434,335 | [
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[TTC-reducing activity of alveolar macrophages under the influence of halothane and nitrous oxide (author's transl)]. | In order to study the influence of two inhalational anaesthetics on metabolic activity of macrophages, we exposed alveolar macrophages (AM) from guinea pigs to both nitrous oxide (N2O) and halothane-N2O in vitro. We examined the enzymatic activity, which is bound to an intact metabolic phase, by application of the trip... | 434,425 | [
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[Investigations about the influence of halothane and enflurane on the nuclear metabolism of bronchial mucosa cells of the dog (author's transl)]. | The influence of halothane and enflurane on the nuclear metabolism of bronchial mucosa cells was investigated over ten hours on 5 dogs each anaesthetized with halothane or enflurane. Desoxyribonucleinic acid (DNS) and, for the arginine and lysine-rich histone fraction the basic amino-acids arginine and lysine were meas... | 434,426 | [
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[On the problem of optimal warming and moistening of the inspired gases in controlled and assisted artificial ventilation (author's transl)]. | The physiological significance of adequate temperature and humidity of respiratory gases and the problems of technical realization are demonstrated. Humidifying and warming of gases by the principle of bubbling through a heated waterbath are believed to be best. The problems with these techniques e.g. dependence of tem... | 434,427 | [
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[Plasmacortisol and parturition under epidural anaesthesia (author's transl)]. | Plasma cortisol was determined by a radioimmuno assay during labour, at and after delivery in 16 primigravidas und epidural anaesthesia and was compared with 13 primigravidas, who delivered under pentazocine or pethidine and pudendal block. Cortisol levels decreased after effective epidural anaesthesia during the first... | 434,435 | [
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Hepatotoxicity and halothane metabolism in an animal model with application for human toxicity. | Centrilobular necrosis and a ten-fold elevation in serum alanine amino-transferase (ALT) consistently followed 2 hours of 1% halothane anaesthesia in an animal model. Conditional factors were the presence of enzyme induction and moderate hypoxia (14% oxygen), indicating an association between reductive metabolism and h... | 434,454 | [
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Indices of myocardial oxygenation during coronary-artery revascularization in man with morphine versus halothane anesthesia. | A prospective study in 12 adult male patients undergoing coronary-artery revascularization was conducted to compare the effects of a morphine versus a halothane anesthetic technique on several indices of myocardial oxygen supply and demand. Indices reflecting myocardial contractility, preload, afterload, and heart rate... | 434,535 | [
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Hyperkalemia-induced conversion of chronic atrial fibrillation to normal sinus rhythm; a case report. | The electrocardiographic manifestations of hyperkalemia have been well described. We report a patient with chronic congestive heart failure and atrial fibrillation for 6 years. who converted to sinus rhythm during an episode of hyperkalemia. To our knowledge, this is the first report of hyperkalemia-induced conversion ... | 434,570 | [
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Progression of a dural arteriovenous malformation resulting in an intracerebral hematoma. A case report. | A progressing, essentially extracranial arteriovenous malformation with purely external carotid feeders can involve the intracranial vasculature by enlargement of its drainage area. Thus it can cause cerebral dysfunction by an intracranial bleed or raised intracranial pressure due to venous engorgement. A case is descr... | 434,578 | [
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Respiratory allergy to algae: clinical aspects. | A comprehensive investigation was done to evaluate the allergenic algae in the Delhi area. Results of 4,000 skin tests performed on 400 patients suffering from naso-bronchial allergy and 300 skin tests on 30 healthy persons with 10 common algae isolated from the Dehli atmosphere are presented and compared. Positive ski... | 434,586 | [
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Farmer's lung disease: long-term clinical and physiologic outcome. | To determine the long-term effects of farmer's lung disease and the factors influening the outcome, 141 patients with farmer's lung disease were evaluated. At the time of the last follow-up, 29 patients had died and 92 (mean age, 54 years) were studied clinically, physiologically, and radiologically. The mean length of... | 434,591 | [
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Accuracy sensitivity to carboxyhemoglobin, and speed of response of the Hewlett-Packard 47201A ear oximeter. | We have shown that the Hewlett-Packard 47201A ear oximeter measures arterial O2 saturation within 95 per cent confidence limits of +/- 4 per cent when arterial blood saturation is more than 65 per cent, but at lower saturations the oximeter consistently provides a reading that is too low. The oximeter is sensitive to c... | 434,601 | [
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Legionnaires' disease: clinical features of the epidemic in Philadelphia. | A review of the medical records of 123 persons with Legionnaires' disease hospitalized in the 1976 Philadelphia epidemic showed that the manifestations of infection ranged from mild grippe to a severe pneumonia that also involved other organ systems. Early in the illness, constitutional symptoms predominated. Fever, ma... | 434,627 | [
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"Endotoxicity" of the Legionnaires' disease bacterium. | The Legionnaires' disease (LD) bacterium is a gram-negative organism whose "endotoxicity" appears to differ in several respects from the classic endotoxicity generally associated with gram-negative bacteria. Discrepancies were noted between the high activity of LD bacteria in gelating limulus lysate in vitro and their ... | 434,647 | [
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A high molecular weight antigen in Legionnaires' disease bacterium: isolation and partial characterization. | We isolated a high molecular weight antigen of the Legionnaires' disease (LD) bacterium by column chromatography. The antigen was composed of 35% carbohydrate, 2.6% protein, 1.8% phospholipid, and 1% 2-keto-3-deoxyoctonate and was important in the host's antibody response because it inhibited the indirect immunofluores... | 434,650 | [
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[Cerebral manifestations of sarcoidosis (author's transl)]. | Sarcoidosis lesions in the brain are relatively rare and can remain latent, or become evident in various forms: meningitic, encephalitic, neuro-endocrinian, vascular, or tumoral. A case is reported of an Antilles patient aged 35 years, in whom the diagnosis was made by examination of an operation specimen, following th... | 434,731 | [
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Frontal sinus mucocele. | Although not uncommon, and certainly not rare, frontal sinus mucocele was seen in 4 cases by the authors. Since one of the cases was rather unusual, we were prompted to evaluate the subject and prepare this manuscript. Gradual onset of unilateral proptosis should make one suspicious of a mucocele involving the paranasa... | 434,734 | [
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[Comparative study of the distribution of semisynthetic cephalosporins in the body of rats]. | Distribution of 6 cephalosporin antibiotics, i. e. cephaloridin, cephalotin, cephradin cephacetryl, cephazolin and cephapyrin for parenteral use was studied comparatively on rats. The studies showed that all the above cephalosporins were well absorbed into the blood after intramuscular administration. The highest serum... | 434,800 | [
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Treatment of scleromyxedema with melphalan. | Scleromyxedema is an uncommon cutaneous fibromucinous disease with a monoclonal protein, which has resisted a number of therapies. Eight cases followed up for as long as 12 years have provided an opportunity to observe the effects of melphalan treatment in this disease. The fibrohistiocytic and mucinous change of the s... | 434,843 | [
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Necrotizing sialometaplasia. A condition simulating malignancy. | Necrotizing sialometaplasia occurred in a 55-year-old woman. The ulcerated lesion on the hard palate was treated conservatively and resolved spontaneously in about three months. The histology of the lesion consisted of coagulative necrosis of the salivary gland lobules and prominent squamous metaplasia within adjacent ... | 434,849 | [
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Systemic lupus erythematosus. Association with previous neonatal lupus erythematosus. | A patient previously reported to have discoid lupus erythematosus as a neonate eventually developed systemic lupus erythematosus (SLE) at age 19 years. This case illustrates that although neonatal lupus erythematosus is usually self-limited, SLE may develop in selected patients in future years. | 434,854 | [
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Subungual osteochondroma. Differential diagnosis and treatment. | Subungual osteochondroma, a rare disorder of the fingers and toes, occurred in five patients. Clinical features of the condition include nail deformation, history of long, slow growth, and characteristic radiologic features. Surgery is directed toward total tumor resection with preservation of the nailbed to achieve no... | 434,874 | [
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Factors affecting neonatal jaundice. | Plasma bilirubin was estimated on 690 term infants on about the 6th day of life. Perinatal factors were recorded and the results analysed. Hyperbilirubinaemia was defined as a level greater than 205 micromol/1 (12 mg/100 ml) and this was present in 20% of cases. Three factors--epidural analgesia, breast feeding, and po... | 434,885 | [
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Duodenal bile acids in infants with protracted diarrhoea. | Bile acids were estimated in the duodenum of infants with protracted diarrhoea and compared with those in a control group. Significantly lower levels of total bile acids were found in infants with protracted diarrhoea, a finding which may be due to ileal dysfunction. Low concentrations of total bile acids may contribut... | 434,889 | [
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0.08741347,
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0.1919641,
0.184709,
0.1018801,
-0.07564294,
... |
Clinical evaluation and comparison of the Infrasonde, Arteriosonde, and mercury sphygmomanometer in measurement of blood pressure in children. | Both systolic and diastolic pressures can be measured in children with the mercury sphygmomanometer, the Arteriosonde and the Infrasonde. Estimates made blindly with these instruments were compared with directly measured intra-arterial blood pressures in 50 children aged between 4 days and 14 years. Systolic and diasto... | 434,903 | [
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0.03646864,... |
Medulloblastoma--a changing prognosis? | 87 of 90 consecutive cases of medulloblastoma diagnosed at The Hospital for Sick Children, London, in the 10-year period 1965-74 were followed-up until death or until 1 January 1978. Only one patient survived in the 1st 5-year period and is a cure. In the 2nd 5-year period 17 (41%) of 41 patients presenting are alive a... | 434,906 | [
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0.1788307,
0.3873571,
0.3003549,
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... |
Foot length--a new and potentially useful measurement in the neonate. | The foot length, occipito-frontal head circumference (OFC), crown-rump, and crown-heel length (CHL) of 123 neonates of gestational ages 26-42 weeks, were measured between 12 hours and 5 days. A gauge, designed and constructed at St Mary's Hospital, Manchester, was used to measure foot length. In term babies (37-42 week... | 434,910 | [
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0.3515742,
0.1323568,
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Half life of theophylline in the preterm baby with apnoeic attacks. | Plasma theophylline levels were measured by an enzyme immunoassay method in 6 preterm babies. The method gave accurate and rapid results. The study showed a considerably prolonged half life of an oral preparation. | 434,914 | [
0.05416959,
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Changes in the blood count of growing rats irradiated with a microwave pulse field. | A group of 20 male rats of mean initial body weight of 65.53 g were irradiated for 7 wk (5 days per wk, 4 hr per day) with an electromagnetic pulse field of the following parameters: working frequency 2,736.5 MHz; repeated frequency 395 Hz; pulse width 2.6 musec; vertical polarization; mean power density 24.4 mW/cm2; a... | 434,926 | [
0.2028299,
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0.1321844,
... |
Vertebral sclerosis in adults. | Narrowing of the intervertebral disc space with sclerosis of the adjacent vertebral bodies may occur as a consequence of infection, neoplasia, trauma, or rheumatic disease. Some patients have been described with backache and these radiological appearances without any primary cause being apparent. The lesions were almos... | 434,941 | [
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0.2858675,
0.2241527,
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0.2465969,
0.3194446,
0.08656... |
Circulating immune complexes and monocyte Fc function in autoimmune diseases. | The phagocytosis of separated and adherent monocytes of patients with systemic lupus erythematosus is subnormal as compared to controls on the basis of latex and yeast uptake. The monocytes from the same patients react with antibody-coated sheep red blood cells in a significantly higher degree than normal monocytes. Th... | 434,951 | [
-0.002099557,
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0.02230023,
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0.4434702,
0.2528568,
0.1407075,
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Reactive pituitary abnormalities in patients with Klinefelter's and Turner's syndromes. | Ten unselected patients with gonadal dysgenesis, three with Klinefelter's and seven with Turner's syndromes, were studied. Two of the patients with Klinefelter's and two with Turner's syndromes had enlarged pituitary fossae. The other six patients had normal sized sella, but showed localized change in the sellar contou... | 434,974 | [
0.1205643,
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-0.03685952,
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Assessment of severity of mitral stenosis by echocardiographic leaflet separation. | Mitral valve area (MVA) determined at cardiac catheterization was compared with M mode echocardiographic measurements in 44 patients with mitral stenosis and no substantial mitral regurgitation. Despite statistically significant correlations, measurements of anterior leaflet motion, including rate of diastolic closure ... | 434,992 | [
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0.341497,
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0.1827261,
0.3940158,
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0.0461117... |
Diagnosis of miliary tuberculosis by cerebral computerized tomography. | We report a case of miliary tuberculosis with symptoms and signs of an intracranial mass. These were found to be multiple tuberculomas by computerized axial tomography (CT scan). We review the pathophysiologic features of intracranial tuberculomas. The CT scan allows a rapid and sensitive diagnosis of intracranial tube... | 435,004 | [
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0.125332,
0.1404591,... |
Systems of care and treatment outcomes for alcoholic patients. | All admissions to the Singer Mental Health Center, Rockford, Ill, with a diagnosis of alcoholism in a one-year period (N = 466) were randomly assigned to one of two inpatient programs. One program, "intensive incare," had a high staff-patient ratio with the operating assumption that intensive staff-patient interaction ... | 435,014 | [
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0.0928238,
0.1800976,
0.2596485,
0.1493704,
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On the malignant potential of acquired short esophagus. | Esophageal adenocarcinoma developed in an esophagus lined with columnar epithelium. The malignant potential of columnar metaplasia complicating long-standing gastroesophageal reflux and the implications of surgical management of acquired short esophagus are discussed briefly. | 435,030 | [
-0.3023936,
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0.... |
Discontinuity between the heart and the pulmonary circulation. Its management with the use of a valved external conduit. | The Hancock conduit that contains a porcine xenograft valve has been used in part of the cardiac repair of 22 patients with complex congenital heart disease. Five patients had a severe form of tetralogy of Fallot; six had pulmonary atresia; five had transposition of the great vessels, ventricular septal defect (VSD), a... | 435,031 | [
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Gastric bypass in the operative revision of the failed jejunoileal bypass. | Fifty-five patients with failed jejunoileal bypasses underwent reanastomosis and gastric bypass at the same operation. One patient died of undetermined cause three months postoperatively. The 54 surviving patients were all relieved of their preoperative symptoms, and 40 patients achieved satisfactory weight control. Te... | 435,057 | [
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0.2002824,
-0.08822... |
[Electron microscopic study of the innervation of the heart conduction system in rats]. | A systemic quantitative electron microscopic analysis on innervation of the sinus node, the atrioventricular node, the bundle of His and its pedicles within the interventricular septum has been performed in intact hearts of mature rats. The data have been obtained on the size of nonmyelinated and myelinated nerve fibre... | 435,090 | [
0.0107452,
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0.213634,
... |
[Intraspecies features of variants in the structure of the arterial bed in dogs and their importance for hindlimb transplantation]. | As a result of detailed studies of the dog anatomy, the authors have concluded that besides generally accepted subdivision of these animals into flabby, rough, strong, lean and gentle types, it is reasonable to subdivide them according to the type of their habitus (brachy-, meso- and dolichomorphous types). In 95 fresh... | 435,102 | [
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Wernicke's and global aphasia without alexia. | It has been proposed that the comprehension of written language requires transcoding from the visual (grapheme) to the auditory (phoneme). It has also been proposed that visual word images can be comprehended without grapheme-phoneme transcoding. We describe three aphasic patients with left hemisphere impairment who ha... | 435,133 | [
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Visual-motor adaptation. Quantitative demonstration in patients with posterior fossa involvement. | Short-term visual-motor adaptation to magnifying spectacle lenses was studied in normal subjects and in patients with nonacute posterior fossa lesions. When normal subjects, looking through magnifying lenses, pointed open loop to targets without viewing their hands, they initially underestimated the distance (magnifica... | 435,135 | [
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... |
Acute anterior myelitis complicating West Nile fever. | A healthy young man developed acute anterior myelitis resembling the "polio syndrome." He had visited an area (the Gulf of Suez) in which West Nile fever is endemic prior to his illness. The course of his febrile illness, the spinal fluid findings, and complement fixation antibody titers established the diagnosis of We... | 435,138 | [
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0.2221098,
0.1453073,
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Delayed meningitis following stapes surgery. | Perilymphatic fistulae, developing even years after stapedectomy, open a communication between the perilymph and middle ear. These fistulae constitute a potential pathway for flora of the middle ear to invade the subarachnoid space by way of the cochlear aqueduct. Our patient developed pneumococcal meningitis 14 months... | 435,139 | [
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0.... |
Conservation surgery in laryngeal cancer and its role following failed radiotherapy. A histopathological and clinical study of 32 cases. | The partial laryngectomy specimens from 32 patients with laryngeal carcinoma were histologically examined by the technique of whole organ sectioning. Twenty-three of these patients had previous irradiation therapy. We identify local criteria for performing conservation laryngeal surgery based on clinical and histopatho... | 435,145 | [
0.1235973,
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Auditory dysfunction with facial paralysis. | A series of 58 patients with idiopathic facial paralysis were studied to determine if a concomitant cochlear or eight nerve auditory dysfunction could be identified with traditional audiologic tests. Results indicated that only those patients with a facial nerve lesion, proximal to the stapedius branch, experienced red... | 435,151 | [
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0.0988... |
Cochlear otosclerosis. A continuing fantasy. | Sensorineural hearing loss without an associated conductive loss cannot be attributed to otosclerosis. | 435,168 | [
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How do you recognize allergy? | A suggested basic approach to the diagnosis of allergic diseases, which involves the characteristics of allergic diseases themselves, is presented. Using these characteristics as basic guidelines in investigation, not only should the condition be diagnosed but main cause or causes and triggering factors should be demon... | 435,178 | [
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0.07111884,
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Response of cattle to inoculation with atypical mycobacteria isolated from soil. | Nine strains of atypical mycobacteria and a strain of the rhodochrous taxon, originally isolated from soil samples collected on the subcoastal plains of the Northern Territory, were inoculated into cattle. Each strain was injected subcutaneously into one animal and into a mesenteric lymph node of another. At 4 and 10 w... | 435,217 | [
-0.09722367,
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0.03114697,
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0.3842019,
... |
Ligand-induced conformational transitions and secondary structure composition of chicken liver pyruvate carboxylase. | Apparent conformational transitions induced in chicken liver pyruvate carboxylase by substrates, KHCO(3) and MgATP, and the allosteric effector, acetyl-CoA, were studied by using the fluorescent probe, 8-anilinonaphthalene-1-sulphonic acid and c.d. Fluorescence measurements were made with both conventional and stopped-... | 435,260 | [
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Mechanism of activation of glycogen phosphorylase by fructose in the liver. Stimulation of phosphorylase kinase related to the consumption of adenosine triphosphate. | 1. A dose-dependent activation of phosphorylase and consumption of ATP was observed in isolated hepatocytes incubated in the presence of fructose; histone kinase and phosphorylase kinase activities were unchanged at doses of this sugar that were fully effective on phosphorylase. The activation of phosphorylase by fruct... | 435,271 | [
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Nuclear and cytosolic distribution of conjugated cholic acid and radiolabelled glycocholic acid in rat liver. | 1. Normally fed and cholestyramine-treated rats were injected through the superior mesenteric vein with different amounts of radiolabelled glycoholic acid and the appearance of radioactivity in bile was measured. 2. In normally fed rats radioactivity appeared in bile within 30 s of injection and reached a maximum after... | 435,286 | [
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0.3186402,
0.271361,... |
The effects of barbiturates on the metabolism of phosphatidic acid and phosphatidylinositol in rat brain synaptosomes. | Barbiturates and diphenylhydantoin inhibit the carbamoylcholine-stimulated increase in 32P incorporation into phosphatidylinositol and phosphatidic acid, but have a relatively slight effect on the incorporation of 32P into these lipids in the absence of carbamoylcholine and no effect on 32P incorporation into phosphati... | 435,289 | [
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0.2923394,
0.1529863,
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Identification of susceptibility to malignant hyperpyrexia in swine. | In vitro muscle contracture responses in swine susceptible to malignant hyperpyrexia (MH) were similar to those found in muscle from humans susceptible to this anaesthetic complication, confirming the suitability of the pig as an animal model for studying MH. The results suggest that there are different degrees of susc... | 435,338 | [
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... |
A new method for measuring PCO2 during anaesthesia. | We have evaluated a new method for measuring the oxygenated mixed venous PCO2 (PVCO2) in patients undergoing general anaesthesia. The lungs were inflated with a gas mixture containing 0% carbon dioxide and then 12% carbon dioxide and the expired gas was analysed both before and after a brief period of breath-holding. P... | 435,344 | [
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0.1118528,
0.1365414,
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0.1518907,
... |
Pili multigemini. Report of a case in association with cleidocranial dysostosis. | A patient with cleidocranial dysostosis developed extensive pili multigemini over the heavily bearded chin and cheek areas. Histological examination of serial sections revealed complicated follicular structures forming from two to as many eight hair shafts. Each hair is formed by a single branch of dermal papilla which... | 435,391 | [
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0.2404809,
0.1186507,
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... |
Phenytoin dependent fibrosis in polyfibromatosis syndrome. | We have followed up the evolution of a polyfibromatosis syndrome in a 20-year-old male treated with diphenylhydantoin for epileptic convulsions. The main symptoms were attributable to fibrosis of the adventitial dermis associated with camptodactyly, knuckle pads, tendinous calcification, osseous hypoplasia of the face,... | 435,394 | [
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0.3514869,
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... |
A retrospective study of induction of labour. | The labour, delivery and state of the newborn were compared retrospectively in a group of women who had labour induced and a group who started labour spontaneously. There were 200 women at term in each group, individually matched for age, parity and social class and with no medical or obstetric complications prior to l... | 435,409 | [
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0.2155758,
0.2632824,
-0.07710255... |
Effect of intrauterine contraceptive device on uterine haemostasis: a morphological study. | The effect of the intrauterine contraceptive device (IUCD) on uterine haemostasis was studied at various stages of the menstrual cycle in a series of 46 patients by light- and electron-microscopy and by following the distribution of an infusion of 51Cr-labelled autologous platelets. The endometrium in contact with the ... | 435,419 | [
0.0166466,
0.4489078,
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0.03500632,
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0.3315207,
0.193265,
0.3242935,
0.06795235,
0.0... |
Isolation of Chlamydia trachomatis from eye secretion (tears). | Shedding of Chlamydia trachomatis in the eye secretion (tears) of patients with either hyperendemic trachoma or paratrachoma was studied. The method of collection of eye secretion with cellulose sponges is proved to be simple, faster, and more practicable and yielded a higher rate of chlamydial isolation than aspiratio... | 435,443 | [
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0.2948467,
0.07211602,
0.18910... |
Ligand-induced changes in membrane-bound acetylcholine receptor observed by ethidium fluorescence. 1. Equilibrium studies. | The interactions between the fluorescent probe ethidium and acetylcholine receptor enriched membranes from Torpedo californica are described. One class of saturable ethidium sites was blocked by alpha-bungarotoxin and therefore reflects direct binding to the receptor (Kd approximately 3 micrometers; stoichiometry--one ... | 435,452 | [
0.2480543,
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0.0632133,
0.2687231,
0.3457645,
0.07648159,
... |
Purification and properties of the hemagglutinin from Wistaria floribunda seeds. | Extracts of Wistaria floribunda seeds contain separable erythroagglutinating and lymphocyte mitogenic activities. We wish to report the purification and characterization of the erythroagglutinating lectin of these seeds. A phosphate-buffered saline (PBS) extract of the ground seeds was made to 50% ethanol and the preci... | 435,474 | [
-0.1011208,
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0.2470912,
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0.1571091,
0.1511096,
-0.05079702,... |
Repression of rRNA synthesis induced by disaggregation in Dictyostelium discoideum. | Cells disaggregated from the slugs of Dictyostelium discoideum continued to incorporate [3H]uridine or [3H]uracil, though at a lower rate than interphase amoebae. Disaggregation brought about a marked increase in the proportion of labeled poly(A)-containing RNA to labeled total RNA. The proportion reached the maximum i... | 435,496 | [
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0.03989863,
0.170271,
0.6666619,
0.2678125,
0.05230296... |
Metabolism of 2-amino-3-phosphono[3-14C]propionic acid in cell-free preparations of rat liver. | Incubation of 2-amino-3-phosphono[3-14C]propionic acid with cell-free preparations of rat liver yielded labelled 3-phosphonopyruvic acid, 2-phosphonoacetaldehyde, 2-aminoethylphosphonic acid and acetaldehyde. No radioactivity was found in phosphoenolpyruvate, pyruvic acid, alanine, and phosphonoacetic acid. When added ... | 435,513 | [
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0.1829759,
0.2034671,
0.3134418,
0.2298184,
-0.1551008,
0.035... |
[Localization of adenine components in chick myofibrils by the ferritin antibody technic]. | The immunochemical method has been proposed to indicate the adenin compounds in isolated myofibrils of striated muscle. Adenosine--containing antigen was prepared by coupling adenosine with bovine serum albumin (adenosine--BSA). Antibodies against adenosine--BSA were labelled by ferritin. The sites of the antigen antib... | 435,520 | [
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0.275575,
0.4757312,
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-0.4956854,
... |
[Calculation of the quaternary structure of the alpha--beta-dimer of hemoglobin]. | The calculation of the structure of haemoglobin alpha--beta-dimer is performed. Calculation is divided into two steps: at the first step highly hydrophobic regions of the subunit surfaces which can provide the stability of the complex are found; at the second--the fitting of this surface regions is carried out. The cal... | 435,530 | [
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... |
[Temperature characteristics of an object during the process of cryofixation by the "freeze--etching" technic]. | When using low temperature methods for preparing water-containing objects in electron microscopy temperature characteristics of different objects was studied during freezing and defreezing depending on different preparation conditions. Temperature characteristics of the object was estimated by means of a storage oscill... | 435,533 | [
-0.1675449,
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0.126119,
0.2265702,
0.2399218,
-0.370622... |
[Chlorophyll-photosensitized reduction of methyl red in detergent solutions]. | Chlorophyll-photosensitized reduction of methylene red with ascorbic acid was studied in micellar solutions of triton X-100. The maximum value of photosensitization was observed in the region 0.1% of triton, approximating the critical concentration of micelleformation. The rate of photoreduction of methylene red was st... | 435,543 | [
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0.1421244,
-0.09925003,... |
[Relationship between the electron structure of phosphates and the problem of ATP synthesis and utilization]. | The nature of macroergic bonds and some problems of ATP formation and utilization are considered in terms of electron structure of phosphates. The main acting compound in the ATP synthesis and in the reactions of transfer and utilization of the energy of macroergic bonds as well, is ATP terminal phosphate or phosphoryl... | 435,548 | [
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... |
Decarboxylation and carboxylation of pyruvate in the living mice. | Mice received intravenously [1- or 2-14C]acetate, [1-, 2- or 3-14C] or [2-14C]pyruvate and were killed 1, 3, 5 or 15 min later. The radioactivity of CO2 or HCO3- of liver or carcass as well as the radioactivity of blood glucose were measured. The ratio of the radioactivity found in these compounds after [3-14C] or [2-1... | 435,553 | [
-0.2956744,
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0.3436245,
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-0... |
[Investigation of essential SH-groups of bacterial formate dehydrogenase]. | Modification of two SH-groups in the molecule of formate dehydrogenase by dithiobisnitrobenzoate or to dacetamide results in the enzyme inactivation. Coenzymes, but not the substrate, protect the enzyme against the inactivation. NAD in the presence of potassium azide completely preserves the enzyme activity. Two SH-gro... | 435,562 | [
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0.03978985,
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-... |
[Activation of glucocorticoid cytoreceptors in rat heart]. | Accumulation of 3H-dexamethasone by the nuclei in a cell-free system was studied. The increase in temperature from 0 degrees to 20 degrees C and treatment of cytosol by KCl (0.4 M) or theophylline (10mM) significantly increased the absorption the bound hormone by the nuclear fraction. Activation of the steroid-protein ... | 435,564 | [
0.04518243,
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0.2924555,
0.6528515,
0.05119327,
-0.0767389... |
[Kinetic and allosteric properties of L-threonine-L-serine dehydratase from human liver]. | It was shown that low concentrations of ATP (1..10(-4)M) and 10-fold concentrations of AMP (1.10(-3)M) at three constant L-threonine concentrations activated the L-threonine dehydratase activity of L-threonine-L-serine dehydratase from human liver, but had no effect on the L-serine dehydratase activity of this enzyme. ... | 435,568 | [
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0... |
[Changes in the phospholipid content of intact mitochondria under mitochondrial swelling in hypotonic sucrose solutions]. | Mitochondrial swelling in hypotonic sucrose solutions is accompanied by a decrease of the amount of phosphatidyl ethanolamines, cardiolipids and their lyso-derivatives. An addition of dicaine (inhibitor of phospholipase) to the incubation medium results in a considerable decrease of mitochondrial swelling and prevents ... | 435,569 | [
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0.2936614,
0.3757503,
-0.07363272,
-0.10260... |
[Inhibition of human granulocyte proteinases by a heat and acid-stable proteinase inhibitor from rabbit serum]. | Several human granulocyte proteinases sensitive to the thermo- and acid-resistant proteinase inhibitor from rabbit serum (TASPI) were revealed, using TASPI-Sepharose 4B. It was found that TASPI inhibits the following human granulocyte proteinases: granules-localized kininogenase and chymotrypsin-like kininase (serine p... | 435,577 | [
0.1298014,
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0... |
[Accessibility of microsomal membrane proteins for protease K]. | The effect of protease K on the microsomal membrane proteins was studied. It was shown that treatment of the microsomal membranes by low concentrations of protease did not remove more than 35% of total membrane proteins. Treatment by higher protease concentrations removed about 50% of the proteins. The residual protein... | 435,584 | [
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0.4883298,
-0.02752807,
-0.2534178... |
Pyrimidine metabolism in erythrocytes of the newborn. | Activities of orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase were found to be significantly higher in erythrocytes from newborn infants than in erythrocytes from adults, and approximated those observed in patients with deficiency of hypoxanthine-guanine phosphoribosyltransferase. Enzyme acti... | 435,586 | [
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... |
Fetal thyrotoxicosis in utero. | A case of fetal thyrotoxicosis in utero in a boy with familial predisposition to thyrotoxicosis is reported. At 26 weeks of gestation fetal hyperkinesia and fetal tachycardia developed. This was preceded by a significant pathologic increase in long-acting thyroid stimulator (LATS) in the mother. The fetal hyperkinesia ... | 435,593 | [
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0.3090416,
-0.3702267,... |
[Monosynaptic reflexes of the cat spinal cord during the development of insulin hypoglycemia]. | Insulin-induced hypoglycemia caused depression of rhythmic monosynaptic EPSP motoneurons of the lumbar cord in acute experiments on narcotized and spinal cats. It was demonstrated that growing depression of monosynaptic transmission was associated with the exhaustion of mediator operative fraction and not with any pre-... | 435,622 | [
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0.02677381,
0.002139989,
0.136296,... |
[Heterogeneity in the distribution of cytochrome P-450 in the liver lobule revealed on exposure to carbon tetrachloride]. | A comparative study was made of cytochrome P-450 content and the histological pattern of the development and elimination of necrotic foci arising in the liver of CBA mice after inhalation of CCl4 vapour. Two hours after the inhalation the content of cytochrome P-450 was reduced by a factor of 1.7, and in 17, 24, and 48... | 435,631 | [
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0.06075776,
0.03714463,
0.03517715,
-0.2394791,
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0.1560054,
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0.001912842,
0.08035287,
0.1995356,
0.4331,
0.1196759,
0.3282929,
0.02732541,
... |
Identification of megakaryocytes, macrophages, and eosinophils in colonies of human bone marrow containing neurtophilic granulocytes and erythroblasts. | Pluripotent hemopoietic progenitors in human bone marrow can be identified by their ability to give rise in culture to colonies that contain more than one lineage of hemopoietic differentiation. Growth of these mixed colonies is supported by media conditioned by leukocytes in the presence of phytohemagglutinin (PHA-LCM... | 435,638 | [
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0.3181407,
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0.008155255,
... |
No effects of levamisole on cytotoxic drug-induced changes of human granulopoiesis. | The effect of Levamisole on the human granulopoiesis was studied in patients randomized to receive, in addition to adjuvant chemotherapy for primary breast cancer, either no other treatment or additional unspecific immune therapy with Levamisole. The reaction of granulopoiesis to the cytostatic drugs, as characterized ... | 435,650 | [
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0.2666303,
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0.5567944,
0.2210648,
0.1628918,
0.2023663... |
A new theory of cochlear function, Part II. | This composite theory is based on the concept of 'Gestalt Function' i.e. the acoustic needs of the 'whole animal' as the vertebrates evolved out of the primordial fish. During the first two hundred million years of terrestrial life, hearing was directed solely to substrate sound. When belatedly the mammals achieved air... | 435,655 | [
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-0.2219921,
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0.07504388,
-0.1828165... |
Effects of certain muscarinic antagonists on the actions of anticholinesterases on cat skeletal muscle. | 1. The effects of some muscarinic antagonists, namely, N-ethyl-2-pyrrolidylmethyl-cyclopentylphenyl glycollate (PMCG), N-methyl-4-piperidyl-phenylcyclohexyl glycollate (PPCG, racemate and R and S enantiomers) and 4'-N-methyl-piperidyl-1-phenyl-cyclopentane carboxylate (G3063) on organophosphate (sarin, soman)- and carb... | 435,681 | [
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0.4841085,
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0.2910571,
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... |
Action of prostaglandin dehydrogenase inhibitors on prostaglandin uptake in rat isolated lung. | 1. The effects of some inhibitors of 15-hydroxy-prostaglandin dehydrogenase (PGDH) have been studied on the inactivation of prostaglandin E2 (PGE2) and 16, 16-dimethyl PGE2 in rat isolated lung. 2. Bioassay was used to show that the inactivation of PGE2 and its methyl analogue, was inhibited by frusemide (10(-3) M), N-... | 435,688 | [
-0.3086148,
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0.5275199,
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0.2787797,
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0.... |
Intrathoracic rib: radiographic features of two cases. | Two cases of intrathoracic rib are presented. In one of these the anomalous rib was not supernumerary, and the investing layers of pleura caused the rib to appear abnormally dense. The relevant literature is briefly reviewed. | 435,695 | [
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0.308132,
0.01299046,
... |
Disease cost in a surgical ward. | Data relating to the cost of caring for individual patients were collected for all patients in a general surgical ward over a six-month period. From this the cost per patient was calculated for various diseases and was found to be related to duration of stay. Postoperative morbidity was important in determining cost. A... | 435,707 | [
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0.06671371,
0.2288836,
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0.1554107,
0.2279319,
0.007553163,
-0.05950... |
Divergent views of hospital staff on detecting and managing hypertension. | A questionnaire about detecting and managing hypertension was answered by 76 out of 110 (69%) doctors and 116 out of 195 (63%) qualified nurses in a large hospital. There was no general agreement on the method of taking diastolic blood pressures or on the level of hypertension requiring treatment. Most of the clinician... | 435,747 | [
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0.1692912,
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0.08753507,
-0.1824915,
-0.1032714,
0.01302... |
Childhood cancer and drugs in pregnancy. | A study was carried out on 11 169 matched case-control pairs of children aged up to 15 years included in the Oxford Survey of Childhood Cancers to see whether an association exists between cancer in children and drugs given to their mothers during pregnancy. The mothers of children who developed cancer reported about 2... | 435,748 | [
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0.2403689,
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0.02664424,
0.5307496,
-0.1098486,
0.1375565,
0.007985167,
0.2436891,
-0.05084061,
0.271... |
Relatives and friends group in a psychiatric ward. | To enable relatives and friends of psychiatric patients in a 30-bed acute admission ward to meet the staff team together a relatives and friends group was initiated. The group was intended to provide a forum for questions about the patients' illness and treatment; allow feelings, such as anger and anxiety, about the pa... | 435,887 | [
-0.1857107,
0.3070321,
-0.1697793,
0.1021807,
0.2797372,
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0.03480249,
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0.0008669025,
0.3636511,
-0.0364464,
0.3137228,
0.1292424,
0.1629113,
0.1169247... |
Glycosylated haemoglobin concentrations in newly diagnosed diabetics before and during treatment. | Concentrations of total glycosylated haemoglobins (Hb A1) were measured in 40 diabetics at diagnosis and at monthly intervals after treatment with chlorpropamide, insulin, or diet alone was begun. The mean Hb A1 concentration at presentation in 16 patients treated with chlorpropamide was significantly higher than that ... | 435,952 | [
-0.3407274,
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0.09145156,
-0.003286255,
0.1675936,
-0.0552116... |
Glutamate as a CNS transmitter. II. Regulation of synthesis in the releasable pool. | Slices of the molecular layer of the dentate gyrus of rat hippocampus were used to study the regulation of glutamate synthesis and release. Net glutamate synthesis increased dramatically during conditions which stimulated the release of glutamate. The rate of glutamine incorporation into glutamate released into the med... | 435,981 | [
0.06760634,
0.151477,
-0.2457716,
-0.2484142,
0.06843331,
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0.1099284,
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0.5145715,
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0.334219,
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0.1897667,
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0.006952514,
0.3375897,
0.3877987,
0.1435263,
0.37496... |
Synthesis and turnover of sulfogalactoglycerolipid, a membrane lipid, during spermatogenesis. | The synthesis and turnover of sulfogalactoglycerolipid (SGG) were studied by in vivo labelling of SGG with 35S. The loss of [35S]SGG from the testes and its appearance in the vas deferens plus epididymis were followed with time. DNA was labelled by administration of [3H]thymidine and the behavior of the two isotopes wa... | 436,008 | [
-0.03715699,
0.02563061,
-0.4068479,
-0.3037242,
0.2129827,
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0.1671027,
0.06929656,
0.4843084,
0.3145057,
-0.300664... |
Circular dichroism studies of native and chemically modified Ca2+-dependent protein modulator. | The structural features of the native Ca2+-dependent protein modulator and two chemically modified derivatives, namely, nitrotyrosyl modulator and alkylated modulator, were examined by circular dichroism. The binding of Ca2+ to the native molecule was accompanied by an increase in helical content from 40 to 49%, with l... | 436,009 | [
-0.2957415,
0.3746023,
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0.2616583,
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0.191342,
-0.2498267,
... |
Effect of irradiance upon the population of Pseudomonas coronafaciens in leaves and symptom expression of halo blight of rye. | The toxin-induced chlorosis caused by Pseudomonas coronafaciens is influenced by irradiance. Three levels of irradiance caused differences in symptom expression but did not affect the rate of increase or final population of viable cells of P. coronafaciens in rye leaves. Distinct and faint halo blight symptoms appeared... | 436,013 | [
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0.08064231,
0.1151389,
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0.724632,
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0.6366171,
0.6025588,
0.054581,
-0... |
Squamous cell carcinoma arising in chronic osteomyelitis. | Analysis of three cases and a review of the recent literature on squamous cell carcinoma arising in osteomyelitis confirm that this is an uncommon condition which may run a less benign course than was earlier believed. The disease affects chiefly middle-aged and older men, usually involves the lower extremity and most ... | 436,028 | [
-0.1613869,
-0.2160446,
-0.4279733,
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0.3033171,
0.1995181,
0.2043173,
0.2359247,
0.3228687,
0.02520241,
0.03475985,
... |
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