title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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[Presence of extracranial cerebral arterial lesions in patients undergoing open heart surgery: a planned approach to a single stage operation (author's transl)]. | The combined approach of extracranial arterial lesions in patients undergoing open heart surgery decreases the high cardiac and neurological morbidity and mortality presented by patients operated sequentially. Besides the anatomically sound simultaneous approach of arch lesions and heart surgery, both to be operated by... | 463,455 | [
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Gastric basal secretion during exercise and restitution in patients with chronic duodenal ulcer. | Gastric basal secretion was studied at rest, in the course of one hour's exertion and one hour's restitution in 10 patients with chronic duodenal ulcer, aged 21-52. The subject performed exercise on a Monark ergometer under a load that gave constant pulse rate acceleration equal to 50% of the age-related maximum. Gastr... | 463,491 | [
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Following eye movements on the absence of central vision. | Following responses to constant velocity and sinusoidally oscillating movements of the whole visual environment were examined in normal subjects wearing blinkers to obscure central vision or subjected to a photo flash to induce a central scotoma, in patients with central scotomas of pathological origin and in one patie... | 463,520 | [
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Smoking during pregnancy--effects on the fetus and on thiocyanate levels in mother and baby. | Twenty-eight mothers smoking 10--20 cigarettes daily during pregnancy had significantly higher serum thiocyanate concentrations at delivery compared in 25 non-smoking controls. The thiocyanate levels were positively correlated to cigarette consumption and inversely correlated to the birth weights of the infants. A high... | 463,536 | [
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Spontaneous labour and elective induction--a prospective randomized study. Behavioural assessment and neurological examination in the newborn period. | The effect of induction of labour on the foetus and the newborn was investigated in a prospective randomized study. 41 neonates were studied after induction at full term by amniotomy and intravenous oxytocin infusion. The infusion rate was regulated by the intraamniotic pressure using the Cardiff infusion pump system. ... | 463,537 | [
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Adynamia episodica hereditaria. Treatment with salbutamol. | Three sibs with adynamia episodica hereditaria are described. Treatment with salbutamol inhalation had a beneficial effect on the duration of their adynamic attacks. Continuous peroral treatment with salbutamol has been tried in these patients resulting in the almost complete prevention of attacks. No serious adverse e... | 463,542 | [
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Different histological manifestation of glomerular lesions in familial systemic lupus erythematosus. | Lupus nephritis in a sister and brother pair was histologically analyzed. The 12-year-old sister showed clinically progressive renal failure and her renal pathology disclosed segmental necrotizing and disorganizing glomerulonephritis. On the contrary, the 14-year-old brother exhibited nephrotic syndrome and his renal b... | 463,557 | [
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C cell carcinoma of the thyroid--papillary type. | Two cases of papillary type of C cell carcinoma of the thyroid were reported. They showed papillary arrangement with fibrovascular stalk in properly fixed tissues. Histochemically argyrophil reaction was positive in the cytoplasm and amyloid deposited in the stroma. Ultrastructurally secretory granules were found in th... | 463,561 | [
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Prolactin and 3-methylcholanthrene induced cervical carcinoma. Effect of bromocriptine. | Female mice of the NMRI strain were injected with estradil for the first five days after birth (estrogenized animals) and ovariectomized at the ages of 6-9 weeks. One week later, a cotton thread impregnated with 3-methylcholanthrene was inserted into the uterine cervix. Starting on the day of insertion of the thread, a... | 463,562 | [
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Weight changes with depot neuroleptic maintenance therapy. | A prospective study of schizophrenic patients prescribed injectable depot neuroleptic drugs as maintenance therapy showed a clinically significant weight gain in 55% of patients. No significant difference was shown between flupenthixol decanoate and fluphenazine decanoate, nor was a clinically meaningful relationship s... | 463,589 | [
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Pathophysiology of blood pressure in the elderly. | Several of the factors responsible for circulatory control are modified in the elderly. Loss of elasticity of the aortic wall produces a widened pulse pressure and a high incidence of systolic hypertension. Attempts to normalize this may be associated with disabling diastolic hypotension. Arterial baroreceptor sensitiv... | 463,675 | [
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The prevalence, severity and factors associated with urinary incontinence in a random sample of the elderly. | A study to determine the prevalence of urinary incontinence in a random sample of a total elderly community is described. The prevalence of incontinence in women aged 65 years or more was found to be 17% and in men 11%. The findings show that the prevalence of incontinence is particularly high among residents of old pe... | 463,679 | [
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Will drugs help patients with Alzheimer's disease? | Recent studies have shown a defect in the cholinergic system of the cerebral cortex of patients suffering from nonvascular senile dementia. This observation suggests the possibility of instituting some kind of replacement therapy and trial have been carried out. At this juncture it seem pertinent to ask what lessons ca... | 463,680 | [
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Vascular pathology in hypertension. | The pathological changes in blood vessels observed in primary (essential hypertension) are similar to those seen in secondary hypertension due to renal disease or other causes. In benign hypertension, the major changes are in the small arteries and arterioles especially in the kidney. Interlobular arteries exhibit inti... | 463,685 | [
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Dysphagia: an evaluation and treatment program for the adult. | Dysphagia, or difficulty swallowing, can interfere with independent feeding in the physically disabled adult. The physiology of normal swallowing and neuromuscular pathology of dysphagia applicable to the occupational therapist are reviewed in this paper. Pertinent nursing care of the respiratory and gastrointestinal t... | 463,718 | [
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Q-aTc interval as a clinical indicator of hypercalcemia. | The charts were reviewed of more than 200 patients discharged from the hospital between 1972 and 1977 with a diagnosis implying abnormal calcium metabolism. When all other variables known to affect the Q-T interval were eliminated, serum calcium concentrations on 65 occasions in 39 patients were found to correlate sign... | 463,762 | [
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The habenular nuclei of the elasmobranch "Scyllium stellare": myelinated perikarya. | Some habenular cells of the elasmobranch, Scyllium stellare, have a perikaryon completely enveloped by myelin of the compact type. They are found only in the left habenula and not in the right. The myelin sheath accompanies the proximal segment of the process arising from the perikaryon, in a node of Ranvier-like patte... | 463,789 | [
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The Clara cell: a comparative ultrastructural study in mammals. | Clara cells in the terminal bronchoiles of mouse, rat, rabbit, calf and human were compared by light, transmission and scanning microscopy, and species-differences were clearly present. Mouse Clara cells were most numerous and mouse and rabbit Clara cells had large dense mitochondria. Rabbit and calf had glycogen in Cl... | 463,790 | [
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Nitrogen balance in obese patients receiving a very low calorie liquid formula diet. | Eleven obese patients were placed on a liquid formula diet containing 320 kcal (1.34 MJ), 31 g protein, 44 g oligosaccharides, 1.5 g fat, vitamins, and essential minerals for a period of 4 weeks under metabolic ward conditions. The diet was well tolerated, and mean weight loss was 2.49 kg/week during the 4-week period.... | 463,799 | [
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Trisomy in the distal end of the long arm of chromosome 3. A condition clinically similar to the Cornelia de Lange syndrome. | A patient had a trisomy for the distal portion of the third chromosome. The major clinical features were failure to thrive, profound mental retardation, dysmorphic head shape, a short nose, anteverted nares, long eyelashes, synophrys, characteristic mouth, and short stature. The similarities between the clinical pictur... | 463,821 | [
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Familial asymmetric crying facies. Its occurrence secondary to hypoplasia of the anguli oris depressor muscles. | Asymmetric crying facies is a common neonatal problem with multiple causes. Asymmetric crying facies occurred in a newborn, secondary to familial hypoplasia of the anguli oris depressor muscle. The differential diagnosis of asymmetric crying facies should include this genetic cause. | 463,824 | [
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Clinical and physiological manifestations of bronchiolitis and pneumonia. Outcome of respiratory syncytial virus. | The physiological abnormalities and clinical correlates of 32 infants consecutively hospitalized with lower respiratory tract disease from respiratory syncytial virus (RSV) were studied in an attempt to characterized the infant most at risk for the acute and long-term complications of RSV infection. Arterial oxygen sat... | 463,835 | [
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Surgical management of ileosigmoid fistula in Crohn's disease. | Seventeen cases with Crohn's disease and ileosigmoid fistula were reviewed. They have been subdivided into four groups according to the anatomic site and extent of disease. Seven patients had disease localized to the terminal ileum and a fistula to normal sigmoid. Five were treated by ileocolic resection and simple of ... | 463,844 | [
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Two cases of complicated intestinal lipoma. Review of small intestinal lipomas. | Two cases of solitary small intestinal lipoma are presented. One occured in the duodenum as a submucosal pedunculated polyp with a bleeding ulcerated surface. This was diagnosed by means of the fiberoptic duodenoscope (Olympus D1G2). The second involved a large massive submucosal lipoma which formed the leading edge of... | 463,854 | [
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The radiology corner. Segmental lymphangiectasia of the small bowel. | A case of intestinal lymphangiectasia, limited to a small segment of jejunum, is reported. This finding reflects part of the spectrum of generalized dysplasia of the lymphatic system. A discussion of the pathogenesis, pathophysiology and roentgen features of intestinal lymphangiectasia as part of a systemic disorder is... | 463,857 | [
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An outbreak of influenza aboard a commercial airliner. | A jet airliner with 54 persons aboard was delayed on the ground for three hours because of engine failure during a takeoff attempt. Most passengers stayed on the airplane during the delay. Within 72 hours, 72 per cent of the passengers became ill with symptoms of cough, fever, fatigue, headache, sore throat and myalgia... | 463,858 | [
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Laterality of breast cancer in families. | A new method for analyzing concordance for a binary variable in extended pedigrees was developed to study tumor laterality in families with high incidence of breast cancer. It was found that related breast cancer patients in 15 high-risk Midwestern US families did not have their tumors on the same side more frequently ... | 463,867 | [
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Acquaintance networks among leukemia and lymphoma patients. | A case-control study of clustering through acquaintanceship among lymphoma and leukemia patients was conducted for the years 1967 through 1972 in Orleans County, New York. Twenty lymphoma and 17 leukemia cases met criteria for inclusion in the study. Data on acquaintanceship linkage were gathered from the source cases ... | 463,871 | [
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Hemolytic anemia due to pyruvate kinase deficiency: characterization of the enzymatic activity from eight patients. | We have studied the red cell pyruvate kinase (PK) variants from eight patients representing five families with pyruvate kinase deficiency-associated hemolytic anemia. The kinetic properties, electrophoretic mobilities, and immunological reactivity with anti-normal red cell pyruvate kinase were determined. The patients ... | 463,878 | [
-0.1303111,
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... |
Testicular sarcoidosis. | A 20 year old black man presented with shortness of breath, hilar adenopathy, monoarticular arthritis, polydipsia and polyuria, and bilateral testicular masses. Transbronchial biopsy revealed noncaseating granulomas consistent with sarcoidosis. Subsequent work-up demonstrated hypothalamic dysfunction, and joint fluid a... | 463,907 | [
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Familial recurrent rhabdomyolysis due to carnitine palmityl transferase deficiency. | Muscle carnitine palmityltransferase (CPT) activity was very low (0 to 14 per cent of controls) in two brothers with a syndrome of recurrent rhabdomyolysis and myoglobulinuria. In isolated muscle mitochondria the majority (87.5 per cent) of total measurable CPT enzyme activity could be attributed to external membrane C... | 463,910 | [
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0.283374,
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-0.... |
How to be less invasive. | Unless cardiac output is reduced, alveolar ventilation can be monitored without arterial blood gas analysis by estimating arterial carbon dioxide tension (PaO2) from rebreathing measurement of mixed venous carbon dioxide tension (PvCO2) (PaCO2 = 0.8 PvCO2). If cardiac output is reduced, the PvCO2 - PaCO2 difference inc... | 463,922 | [
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0.04634142,
0.153094,
... |
Fever and pulmonary thromboembolism. | Fever patterns associated with pulmonary thromboembolism have not been well characterized. Upon review of 35 consecutive patients with angiographically documented pulmonary emboli, fever was present in 24 patients; and in 20, it was attributed solely to pulmonary thromboembolism. Analysis of these cases indicates that ... | 463,928 | [
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0.1072055,
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Modern management of the breech delivery. | Retrospective review of 457 breech deliveries failed to reveal a significant improvement in neonatal mortality and morbidity rates for those delivered by cesarean section vs. vaginal delivery. A slight but insignificant improvement in salvage was found for the 1,000 to 1,500 gram weight category when delivery was by ce... | 463,950 | [
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Case report. Clinical manifestations and treatment of Legionnaires' disease. | Eight patients with atypical pneumonia caused by the Legionnaires' disease organism were seen during the spring and summer of 1977. Two died of the acute illness. All patients were febrile and presented with symptoms of acute respiratory infection. Other symptoms included malaise, anorexia, chills, myalgia, and headach... | 463,949 | [
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0.01137751,
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Premature rupture of the membranes: a conservative approach. | A conservative approach was followed in 188 patients with premature rupture of the membranes (PROM) over a 2 year period. There were no neonatal deaths from sepsis, and only one infant showed a positive central bacteriologic culture. Fifty-seven percent of all patients less than 37 weeks' gestation had a latent period ... | 463,957 | [
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0.1316468,
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The effect of pregnancy on the cervical squamocolumnar junction in patients with abnormal cervical cytology. | During a 6 1/2 year study period the author used colposcopy to evaluate 174 pregnant patients with abnormal cervical cytology. Of these patients, 42% had an exocervical squamocolumnar junction. In those patients beyond the age of 25, or with a parity greater than 1, 80% had endocervical junctions. The predominant effec... | 463,976 | [
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0.0966792,
... |
Estriol determinations in diabetic pregnancies complicated by nephropathy. | In order to study the effect of renal disease on urinary estriol clearance rate, we have measured the concentrations of plasma and urinary estriol (E3) in pregnancies of 69 diabetic patients, 25 of whom had nephropathy. No correlation was found between endogenous creatinine clearance (CCr) and estriol clearance (CE3) r... | 463,978 | [
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0.07926003,
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0.1913892,
0.1029276,
... |
Time analysis of corneal endothelial cell density after cataract extraction. | Serial endothelial photographs were taken preoperatively and postoperatively in 200 eyes; 111 eyes contained a Rayner iris clip lens, 54 eyes contained a Fyodorov Sputnik lens, and 35 eyes had no lens. Central endothelial cell density was changed in all instances, with counts in implanted eyes declining 25 to 30%, and ... | 464,015 | [
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0.1225405,
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0.06560698,
0.1110... |
A phenomenologic description of clot lysis in dilute human plasma correlating structure and function of platelets. | Platelets in a dilute platelet-rich plasma clot formed by the addition of thrombin at 4 C do not lose their alpha-granules or develop platelet-fibrin interconnections. These clots do not retract or lyse. If after clot formation for 30 minutes the clots are transferred to 37 C, the alpha-granules then disappear from the... | 464,023 | [
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0.02057152,
-... |
Treatment with a position feedback-controlled head stabilizer. | A position feedback-controlled head stabilizer has been developed to provide cerebral palsied individuals with resistive exercise to strengthen the neck musculature. This apparatus detects "involuntary" head motion and stabilizes the head by applying opposing forces; it also can be used to facilitate muscular contracti... | 464,029 | [
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... |
Telemetered electromyography of flexor digitorum profundus and flexor digitorum superficialis in Pan troglodytes and implications for interpretation of the O. H. 7 hand. | The importance of knuckle-walking in the locomotor repertoire of African apes raises the possibility that the long digital flexors may be specially adapted more to meet the demands of ground quadrupedalism than those of suspension. To investigate this possibiltiy, the activities of the flexor digitorum superficialis an... | 464,032 | [
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0.003789418,
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Placental alkaline phosphatase: population studies in Sardinia and data on the anthropological value of this genetic marker. | The analysis of human placental alkaline phosphatase polymorphism in Sardinia has shown a further difference in the genetic structure of this population in comparison with the populations of Continental Italy and Western Europe. Ethnic and geographic variations in world distribution of placental alkaline phosphatase ge... | 464,033 | [
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Effect of chemotactic factors on calcium levels of rabbit neutrophils. | Studies were undertaken to provide a systematic investigation of the effect of the chemotactic factor, formyl-methionyl-leucyl-phenylalanine (F-Met-Leu-Phe), on the levels of total and exchangeable calcium in rabbit neutrophils. The 45Ca2+ specific activity of the cells was thus determined before and after stimulation ... | 464,041 | [
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Depressed responsiveness of the carotid sinus reflex in conscious newborn animals. | The responsiveness of the carotid sinus reflex was evaluated by comparing the effects of bilateral carotid occlusion (BCO) in conscious adult dogs and puppies on measurements of arterial pressure, cardiac output, heart rate, and calculations of total peripheral resistance (TPR). In eight adult dogs, BCO increased mean ... | 464,068 | [
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0.08528268,... |
Renal vascular resistance and reactivity in the spontaneously hypertensive rat. | Renal vascular resistance is elevated in spontaneously hypertensive rats (SHR) when compared to normotensive control Wistar-Kyoto rats (WKY). The present study examined possible determinants of this raised vascular resistance in in situ autoperfused kidneys of pentobarbital-anesthetized, 12- to 16-wk-old SHR and WKY. O... | 464,097 | [
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-0.1033... |
Effect of sympathetic nerves on cerebral vessels during seizures. | The purpose of this study was to determine the effect of activation of sympathetic pathways during seizures on cerebral blood flow and integrity of the blood-brain barrier. We measured cerebral blood flow with microspheres and disruption of the blood-brain barrier with labeled albumin in cats. One cerebral hemisphere w... | 464,110 | [
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Quantitative study of intramyocardial compression in the fibrillating heart. | Extravascular compression inhibits coronary blood flow in fibrillating hearts. Pressure-flow curves from spontaneously fibrillating hearts whose coronary arteries were maximally dilated were examined to see whether this inhibition involves a vascular waterfall mechanism as has been found in the beating heart. Waterfall... | 464,112 | [
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... |
Myocardial adenosine salvage rates and restoration of ATP content following ischemia. | The isolated perfused rat heart was utilized to determine the maximum rate of adenosine incorporation into adenine nucleotides and the effect of ischemia on this rate. In aerobic hearts, the rates of [8-14C]adenosine incorporation into nucleotides in nanomoles/minute per gram dry tissue were ATP 34 +/- 2, ADP 6 +/- 0.4... | 464,118 | [
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0... |
Intramural PCO2: a reliable index of the severity of myocardial ischemic injury. | The present study was performed to evaluate the usefulness of changes in intramural oxygen (PmO2) and carbon dioxide (PmCO2) tensions shortly after coronary artery occlusion as indices of the severity of myocardial ischemic injury. In 14 open-chest, anesthetized dogs, a 60-min coronary artery occlusion was performed, d... | 464,119 | [
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Nonpressor mechanisms in CNS-induced natriuresis. | Ventriculocisternal perfusion was performed in pentobarbital-anesthetized dogs. Perfusion of high Na (300 mM NaCl) artificial cerebrospinal fluid (CSF) (E) for 2 h was preceded by 2 h of control (C) and was followed by 2 h of recovery (R) during which normal (150 mM NaCl) artificial CSF was perfused. A time-control gro... | 464,123 | [
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... |
Human hyperthermic therapy: relation between tumor type and capacity to induce hyperthermia by radiofrequency. | There is mounting evidence that hyperthermia of 42 degrees C or greater is tumoricidal to cell cultures and to animal and human tumors. However, temperatures of 45 degrees C or greater may have greater potential therapeutic benefit. The ability to selectively achieve such highintratratumor temperatures without injury t... | 464,205 | [
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A new method of preclotting fabric prostheses. A preliminary report. | A new method of preclotting arterial fabric prostheses is described. The preclotting process depends on infusion of blood into a polyethylene bag containing the prosthesis. Massage of the bag aids permeation of the graft, and a second infusion of blood over a 1 minute period seals the fraft completely. Rapid preclottin... | 464,232 | [
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... |
A simple method for atraumatic control of small vessels. | The use of a surgical clip to maintain tension on an elastic band provides gentle temporary occlusion without special instruments or equipment. | 464,243 | [
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Evidence for an input to the molecular layer and the stratum granulosum of the dentate gyrus from the supramammillary region of the hypothalamus. | Injections of a mixture of tritiated amino acids were made into the posterior hypothalamus in a series of rats and cats. In every case in which the injection involved a significant proportion of the cells in the supramammillary region, labeled fibers could be followed to the dentate gyrus, the anterior hippocampal rudi... | 464,319 | [
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... |
Hemodynamic effects of phentolamine in mitral stenosis and congestive cardiomyopahty. | Nine patients with alcoholic cardiomyopathy and 8 patients with mitral stenosis were studied by right and left heart catheterization. Hemodynamic observations were made during control period and during the infusion of phentolamine at a rate of 0.3 mg per minute. The patients with the cardiomyopathy responded to phentol... | 464,340 | [
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Medical management of hypertension. | In a paper like this, with such diverse information, it is impossible to summarize the content completely. Suffice it to say that a stepwise approach to the management of essential hypertension has been presented, beginning with a diuretic agent as the cornerstone of management for most patients. Recommendations for th... | 464,344 | [
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Efficacy of an inactivated virus vaccine for prevention of porcine parvovirus-induced reproductive failure. | Gilts vaccinated IM either once (4 gilts) or twice (2 gilts) with an acetylethyleneimine-inactivated porcine parvovirus (PPV) vaccine before they were bred were subsequently exposed intranasally and orally to virulent PPV at about the 40th day of gestation (from 37 to 43 days). At 2 weeks after vaccination, all had hem... | 464,358 | [
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Evaluation of a cuprimyxin-hydrocortisone acetate suspension in the treatment of otitis externa in dogs and cats. | The therapeutic efficacy of a 0.5% cuprimyxin plus 1% hydrocortisone acetate-water-base suspension was evaluated in 130 clinical cases of otitis externa in dogs and cats in various geographic areas of the United States. The otic microbial flora was studied before treatment in 125 (96%) of the dogs and cats, with multip... | 464,367 | [
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Disseminated Mycobacterium chelonei infection: response to sulfonamides. | A disseminated infection due to Mycobacterium chelonei occurred in a hemodialysis patient after rejection of his second renal transplant. Painful subcutaneous nodules and abscesses were found on both legs. Therapy with sulfisoxaxole and kanamycin produced a prompt response twice, as did sulfisoxazole alone on 2 additio... | 464,378 | [
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Lung function in children with sickle cell anemia. | Lung volumes and expiratory flows were measured in 12 children with sickle cell anemia and 12 height-matched black control subjects. Diffusing capacity of the lung for CO, pulmonary capillary blood volume, the membrane component of diffusing capacity, arterial blood gases on breathing room air and 100 per cent O2 were ... | 464,381 | [
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Reactive hyperreninemia in renovascular hypertension after angiotensin blockage with saralasin or converting enzyme inhibitor. | Baseline plasma renin activity and responses to saralasin and converting enzyme inhibitor SQ 20881 (teprotide) in 47 untreated patients with surgically correctable renovascular hypertension were compared to those in 100 patients with high- and normal-renin essential hypertension. All 32 renovascular patients on normal ... | 464,461 | [
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Obstruction of the proximal right coronary artery with acute inferior infarction due to blunt chest trauma. | Two patients developed an acute transmural myocardial infarction due to severe obstruction of the proximal right coronary artery after blunt chest trauma. Neither had a history of ischemic heart disease, and both had an arteriographically normal left coronary artery. In one patient significant resolution of the subtota... | 464,463 | [
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[Surgery of the facial nerve (author's transl)]. | The indication of facial nerve surgery are wider than currently believed. The incision of the fibrous sheath, the suture termino-terminal, the nervous graft even very long, the hypoglosso anastomosis give all better results than all other surgical technics. The potentiality of nervous regeneration exist in old people a... | 464,520 | [
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0.110223,
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Fibrinolytic activity in patients with acute tonsillitis. | Three parameters in blood fibrinolysis, viz, the levels of fibrinogen, plasminogen, and fibrinogen and/or fibrin degradation products (FDP), were measured in patients with acute tonsillitis and the results were compared with those for healthy adults. The fibrinogen content in acute tonsillitis increased significantly (... | 464,529 | [
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A simple micromethod for 25-hydroxyvitamin D estimation. | A quick and simple method for estimating 25-hydroxyvitamin D is described, It involves dichloromethane extraction followed by competitive protein-binding assay without chromatography. This assay can be performed on 100 microliter of serum and enables 50 samples to be estimated in one working day. The simplicity, speed,... | 464,537 | [
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0.14748... |
Re-examination of effect of paracetamol on serum uric acid measured by phosphotungstic acid reduction. | The drug paracetamol (N-acetyl-p-aminophenol; acetaminophen) caused a spurious increase in serum uric acid measured by phosphotungstic acid reduction methods. However, the increase was less than 0.12 mmol/1 at plasma levels of paracetamol found in overdosage (40 mg/100 ml) and was small at therapeutic concentrations (l... | 464,539 | [
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... |
Carcinogen activation by human uterine enzymes. | Three topics are briefly reviewed relating to carcinogenesis of estrogen responsive tissues: (a) enzymology of benzo(a)pyrene activation by human tissues, (b) microsomal activation of estrogens to estrogen arene oxides and (c) estrogen and progesterone receptor studies in endometrial carcinoma. The following working hy... | 464,542 | [
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In vitro activity of mezlocillin and its related compounds against aerobic and anaerobic bacteria. | A total of 900 clinical isolates of aerobic (462 isolates) and anaerobic (438 isolates) bacteria were tested against mezlocillin in comparison with other penicillins, and the aerobes were also tested against cephalothin, cefoxitin, and cefamandole. Among penicillins, mezlocillin was the most effective against Escherich... | 464,578 | [
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0.2469... |
Comparison between agar and broth minimum inhibitory concentrations of cefamandole, Cefoxitin, and cefuroxime. | The in vitro susceptibility to cefamandole, cefoxitin, and cefuroxime of clinical isolates of Streptococcus faecalis, Klebsiella, and indole-positive Proteus was assayed using minimum inhibitory concentration (MIC) determinations in broth and on solid media. It could be demonstrated that the agar dilution MICs obtained... | 464,588 | [
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Lowered cutaneous and urinary levels of polyamines with clinical improvement in treated psoriasis. | Polyamine metabolism is important in cell proliferation and may play a role in the epidermal cell hyperproliferation of psoriasis. We have determined changes in polyamine levels in skin and urine accompanying clinical improvement in psoriasis following topical therapy. Nine hospitalized patients were examined at the be... | 464,623 | [
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[Skin impedance and phoreographic index in psoriasis. Relationship with action kinetics of three treatments]. | In a previous study, impedance measurements and phoreographic response were shown to quantify significant differences between involved and non-involved skin in psoriasis. The same techniques were used to objectivate the evolution on skin condition on patients treated with dioxyanthranol, difluprednate, and photochemoth... | 464,640 | [
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Interaction of methotrexate and betamethasone with experimental phototoxic inflammation to PUVA (Psoralen and UVA) in mice. | The influence of methotrexate and of betamethasone on a following phototoxic reaction to 8-methoxypsoralen and long-wave ultraviolet light (PUVA) was studied in the mouse. High PUVA doses were not influenced by the two drugs tested. Both methotrexate and betamethasone tended to diminish the PUVA response when psoralen ... | 464,643 | [
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Infusion of the branched chain amino acids in postoperative patients. Anticatabolic properties. | Postinjury metabolism is characterized by breakdown of muscle protein as substrate for energy production and gluconeogenesis and by the resultant loss of lean body mass and weight loss. The branched chain amino acids (BCAAs) which are principally oxidized by the skeletal muscle have been implicated in recent in vitro a... | 464,673 | [
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Initial treatment of sigmoid volvulous by colonoscopy. | The initial management of acute, nonstrangulated sigmoid volvulous is to attempt proctosigmoidoscopic, rectal tube, or barium enema reduction and evacuation. If unsuccessful emergency surgery is necessary. The flexible colonoscope offers an additional therapeutic modality to effectuate preoperative reduction of the twi... | 464,675 | [
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Recurrence after a surgically induced remission. | In December 1976, an 18-year-old woman had symptoms typical of Cushing's syndrome. Laboratory evaluations and roentgenograms documented pituitary-dependent Cushing's disease in a patient with a pituitary microadenoma. In May 1977, she underwent transsphenoidal pituitary exploration. A 2-mm pituitary microadenoma was re... | 464,713 | [
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Specific lamellar structures of agranular endoplasmic reticulum in the senile mouse adrenal cortex. | In the adrenal cortex of old mice, lamellar bodies of various shapes frequently appear in the zona reticularis cells. These structures consist of electron dense plates, about 20 nm in width, closely piled at regular distances of about 25 nm. Each plate displays two sheets of unit membranes enclosing a dense material an... | 464,752 | [
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Total subperiosteal resection treatment of solitary bone cysts of the humerus. | The solitary bone cyst is most frequently located in the upper arm and the average age of the affected patients is between 7 and 9 years, thus perceptibly lower than in cases where solitary bone cyst occurs elsewhere, where the average age is 15. The tendency towards recurrence before 10 years of age is twice as great ... | 464,758 | [
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Femoral neck fractures following surface replacement. | A femoral neck fracture following surface replacement of the hip has been studied and five potential causes of failure were noted. These consisted of; removal of a hip nail during surgery, use of a too small femoral cup, initial reaming in varus, notching of the femoral neck, and failure to completely seat the cup. | 464,766 | [
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0.0495825... |
EMG needle electrodes: electrical impedance. | The electrical impedance of samples of stainless-steel monopolar needle electrodes and concentric electrodes from 3 manufacturers were measured in 154mM saline solution using sine-wave excitation at 4 frequencies from 10Hz to 10kHz. Current densities of less than 2.5x10(-5) amp/cm2 were used. Measurements on both needl... | 464,781 | [
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[Formation of the microcirculatory bed of the muscle coat of the wall of the sigmoid colon during human fetal development]. | During intrauterine life microcirculatory bed of the muscular coat is forming and developing in accordance with its differentiation, growth and functional changes at various steps of its ontogenesis. This step-like differentiation in the parts composing the microcirculatory bed and the whole microcirculatory network of... | 464,822 | [
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[Insecticide poisoning. Microdissection of nerves and muscle histochemistry in 10 cases]. | A sural nerve and a muscle biopsy study of patients with chronic insecticides poisoning, with teased fiber preparations, routine pathologic studies of nerves and histochemistry of muscle is reported. The sural nerves of ten patients were studied and a teased fiber preparation was done in nine. The tenth patient had onl... | 464,859 | [
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The Leboyer method. | The method described is the reception of the newborn on the assumption that the baby is a sensitive, feeling being. The reasons for Leboyer's concept are discussed and the benefits to the parent-child bond are emphasized. | 464,900 | [
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An evaluation of salivary scintigraphy in Sjögren's syndrome. | Sequential salivary scintigraphy, labial salivary gland biopsy, and measurement of stimulated parotid flow rate were performed in 50 patients suspected of having Sjögren's syndrome. The value of these tests in the diagnosis of this disease was compared. Salivary scintigraphy and labial salivary gland biopsy can be used... | 465,095 | [
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0.4406885,
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0.140... |
Pharmacokinetic monitoring of salicylate therapy in children with juvenile rheumatoid arthritis. | Free and total (sum of free and protein bound) salicylate concentrations in serum were determined in 17 children (age: 4-17 years) with definite juvenile rheumatoid arthritis. These measurements were carried out immediately before and 2, 4, and 8 hours after the morning dose during a strict 8 hourly aspirin treatment r... | 465,097 | [
-0.1578661,
0.1878636,
-0.1966353,
-0.1776145,
0.1998654,
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0.2640382,
0.04356139,
-0.07888449,
0.1290175,
0.2190228,
-0.04415686,
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0.2060868,
-0.1585929,
0.3452127,
0.0005436054,
0.4255436,
0.4994119,
0.02720252,
0.06610435,
0... |
[False tumor of the posterior mediastinum in a case of portal hypertension (author's transl)]. | A man of 37 years of age developed portal hypertension which was observed on radiological examination as a mediastinal opacity having the appearance of a tumor. No oesophageal varices were seen on barium meal examination or by endoscopy. A smooth liver was seen during laparoscopy. Pre-operative hemodynamic studies show... | 465,146 | [
-0.2139872,
-0.2009154,
-0.4860501,
-0.0801935,
0.03389462,
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-0.3462364,
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0.1116918,
-0.0224076,
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-0.3286408,
0.313826,
0.1778726,
-0.2655644,
0.4860066,
0.05570972,
-0.2050749,
... |
[Microglia-type cells in normal and pathologic human embryonic brains]. | The brains of 7--12 week embryos, developing in normal and mentally ill females (normal--14, schizophrenia--12, other mental disorders--10) were studied by means of electron microscopy. It was established that the cells of the microglia type may be encountered in the brain of embryos beginning from 7 weeks. In the brai... | 465,151 | [
-0.0346368,
0.3059718,
-0.1252112,
0.1342531,
0.320095,
-0.2345298,
-0.1435318,
0.007562032,
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0.07319164,
-0.09115613,
0.1330354,
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0.239902,
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-0.5059506,
0.09733601,
0.06167666,
0.2234474,
0.09622732,
0.3435815,
-0.02276974,
... |
[Evolutionary study of 81 children with celiac disease]. | A review of 81 children with celiac disease over a period of 5 years is presented. These cases were seen at the Gastroenterological Unit of the Hospital de Nińos Roberto del Río, during years 1970 through 1972. 62% of the patients (50) were placed under control of their disease, the rest were studied and diagnosed only... | 465,175 | [
-0.1511323,
-0.5070441,
0.09937817,
0.1974343,
0.01015606,
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0.07167105,
0.0364916,
-0.2715699,
0.1094427,
0.465307,
-0.1105318,
-0.07669197,
-0.4078834,
-0.3376707,
-0.2527296,
0.09627207,
-0.2201783,
0.1949873,
-0.159522,
0.09282534,
-0.1012838,
... |
[The battered child syndrome. Preliminary review in a Bolivian pediatric hospital]. | Taking into account the prevalence of child abuse in countries with different socioeconomic levels, the authors review this entity through the casuistics in a Bolivian pediatric hospital. Besides confirming unquestionable clinical findings, it was observed that among twenty-seven cases there was a predominance in presc... | 465,194 | [
-0.3643016,
0.03857111,
0.2866871,
0.01334666,
-0.1831985,
-0.1519183,
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0.1049674,
0.2155775,
0.2019768,
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-0.1141602,
-0.332617,
0.1417009,
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0.04627,
0.04737726,
0.09254058,
-0.155174,
0.1527993,
-0.1246407,
-0.1337148,
-0.03... |
Mitral stenosis with high left ventricular diastolic pressure. | Three patients with mitral stenosis are described, in whom the haemodynamic findings at cardiac catheterisation were more suggestive of left ventricular myocardial disease, in that the left ventricular diastolic pressure was high and the mitral valve gradient small. However, their echocardiograms showed abnormal wall m... | 465,208 | [
-0.3495499,
0.3885153,
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-0.1101832,
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0.07767168,
0.0381775,
0.1297934,
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0.1018909,
0.2466468,
-0.1171412,
-0.1834463,
0.3732326,
-0.08431681,
-0.07215339,
0.3620326,
-0.09831053,
0.0085425... |
Reduction of early ventricular arrhythmia by acebutolol in patients with acute myocardial infarction. | To assess the effects of intravenously administered acebutolol (1-20 mg every 4 hours for 24 hours) on cardiac rhythm and performance, we studied 72 patients with evolving myocardial infarction. Twenty-five patients were treated with acebutolol beginning 6 hours after the first increase in the level of plasma creatine ... | 465,240 | [
0.007927323,
0.2080783,
-0.8177404,
-0.4636462,
-0.1411142,
-0.4554724,
0.02780367,
-0.1264026,
-0.1124999,
-0.3939002,
-0.0869216,
0.4266217,
-0.1276417,
0.3318313,
0.123066,
0.1111042,
-0.1408181,
0.1304816,
0.1982794,
0.2667997,
-0.02438424,
-0.008164249,
-0.1672932,
... |
Clinical electrophysiological effects of propranolol on normal sinus node function. | In 35 patients aged 18 to 69 years (mean 48) with clinical, electrocardiographic, or electrophysiological evidence of normal sinus node function, the effect of intravenous propranolol (0.1 mg/kg) was assessed on 3 indices of sinus node function. The drug significantly prolonged sinus node cycle length (12%), slightly p... | 465,245 | [
-0.03813596,
0.000193111,
-0.7162049,
-0.2238302,
0.1854845,
-0.3384911,
-0.03210745,
-0.1461609,
-0.1170782,
-0.147987,
-0.1731825,
0.1872937,
-0.2211915,
0.05165456,
0.06966443,
-0.3697327,
-0.3239567,
-0.008482289,
0.1084446,
0.1392251,
0.1187312,
0.1963108,
-0.0342518... |
Alternating atrial and ventricular tachycardia. | A patient with alternating atrial and ventricular tachycardia is described. He had an acute myocardial infarction and was taking digitalis. The atrial tachycardia, which was occasionally associated with aberrant ventricular conduction, was able to interrupt the ventricular tachycardia though the reverse was not true, s... | 465,249 | [
-0.5233434,
0.3435611,
-0.5113855,
-0.3755831,
0.2838435,
-0.2012646,
-0.3311258,
-0.1454308,
-0.1797951,
-0.1467376,
0.2619939,
0.6453568,
-0.199454,
-0.03425746,
-0.131262,
-0.3947272,
-0.5398014,
-0.02779571,
-0.1347964,
-0.7659848,
0.1674361,
-0.08210524,
-0.1582833,
... |
Presynaptic effect of I.V. anaesthetic agents at the neuromuscular junction. | The effect of Althesin, diazepam, ketamine, propanidid and thiopentone on the release of acetylcholine was tested at the mouse neuromuscular junction. Althesin, diazepam and thiopentone increased the quantal content of the end-plate potential. Ketamine at low concentration (3.6 micromol litre-1) had a similar effect, b... | 465,258 | [
-0.4380991,
-0.3956628,
-0.4705581,
-0.112383,
-0.1447258,
-0.2838213,
-0.1834995,
-0.007604006,
0.04725666,
-0.1321338,
-0.1330135,
0.5090901,
0.1847263,
0.2531308,
-0.2669663,
0.03113055,
-0.4178315,
-0.01908001,
0.02397699,
0.5025274,
0.1483994,
-0.009547288,
0.3688342... |
Extradural analgesia for caesarean section: a comparison with general anaesthesia. | Thirty-two patients received lumbar extradural anaesthesia for elective Caesarean section. The results obtained from this series were compared with those from a similar (control) group of parturients who received general anaesthesia. The extradural group (mothers and infants) were metabolically acidaemic relative to co... | 465,260 | [
0.1664637,
0.04252142,
-0.1862067,
-0.1651843,
-0.280147,
-0.2240022,
-0.3367082,
-0.3565513,
-0.1809797,
-0.02081608,
-0.1133712,
0.1449863,
0.01818085,
0.039652,
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-0.2662514,
-0.3073905,
0.0881935,
-0.1137842,
-0.01034862,
0.1518625,
0.2664995,
0.01633037,
... |
Pharmacokinetics, pharmacology of atenolol and effect of renal disease. | 1. The pharmacokinetics of intravenous and oral atenolol (50 mg) in six healthy volunteers was studied. Plasma, saliva and urine were collected up to 24 h after each dose. 2. There was no significant difference in atenolol half-life when administered by the two routes. Bioavailability of the orally administered atenolo... | 465,278 | [
-0.1804288,
-0.005459751,
-0.5155852,
-0.2147102,
0.2334211,
-0.1815735,
-0.2129532,
-0.01677956,
-0.2051085,
-0.2332665,
0.1543659,
0.1834662,
0.06919213,
0.3060647,
-0.4089004,
-0.2138014,
-0.5644637,
0.3179577,
-0.03988077,
0.09568829,
0.209594,
0.3739429,
0.01660625,
... |
Total urinary and free serum hydroxyproline in metastatic bone disease. | The present study examines the possibility of correlation between free serum and urinary total hydroxyproline and whether this correlation can be applied to clinical conditions. The correlation between the two indices was 0.80 (P less than 0.001) in 18 patients, mostly suffering from malignant disease. On comparing the... | 465,297 | [
-0.2343138,
0.06161279,
-0.2451498,
-0.2192816,
-0.1748634,
-0.5548934,
-0.1016007,
0.1958566,
-0.1663057,
0.171452,
0.1990823,
0.3209871,
-0.05013967,
-0.059814,
-0.6539555,
-0.2395018,
-0.0584192,
0.1785843,
-0.1198916,
0.1804527,
0.3349249,
-0.003487127,
-0.03807893,
... |
Rupture strength of skin wounds in jaundiced rats. | The rupture strength of 7-day-old wounds in normal rats, in rats in which there had been a previous skin incision, and in sham bile-duct-ligated and bile-duct-ligated jaundiced groups of rats was studied. It was found that wounds in jaundiced rats were significantly weaker than the wounds in the normal group of rats. S... | 465,303 | [
0.2689065,
-0.237357,
-0.1436469,
-0.1076382,
0.1267382,
-0.1354648,
-0.3617328,
-0.1879989,
0.04292041,
-0.03962086,
0.1857391,
-0.1194611,
-0.02650641,
-0.01903667,
-0.3439603,
-0.3094725,
-0.341877,
0.1491453,
-0.2408834,
0.02709715,
0.1139141,
-0.160494,
0.1614347,
... |
HLA system in relation to carbohydrate metabolism in lichen planus. | HLA antigens were determined in a group of fifty-two patients with lichen planus. In the group as a whole the frequency of A28 was increased but not significantly so. When the patients were subdivided according to the results of an oral glucose tolerance test, however, a highly significant increase in the frequency of ... | 465,316 | [
0.2003394,
-0.22016,
0.03531078,
0.2281166,
0.1382959,
-0.6266333,
-0.03638671,
0.3717043,
0.2667305,
-0.06104926,
0.009576482,
-0.04144768,
0.1579178,
-0.0008029034,
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-0.2273197,
0.2532661,
-0.06929221,
-0.3184633,
0.1584855,
0.3352944,
-0.288622,... |
Ferritin as a cytosol iron transport intermediate in human reticulocytes. | The major iron-bearing cytosol components of human reticulocytes identified after incubation with 59 Fe-125I-transferrin have been studied further. Component C previously found to behave consistently as an intermediate in the iron transport pathway to haem is shown to consist entirely of ferritin. After a short pulse o... | 465,371 | [
-0.3311757,
-0.0334261,
-0.2028965,
0.1016911,
0.3387327,
0.01363237,
-0.08759221,
0.1722775,
-0.06897563,
0.3146304,
-0.09861936,
0.4419669,
0.1270998,
-0.007359131,
-0.2791724,
-0.1763476,
-0.1275075,
-0.03828886,
-0.1672877,
0.06308226,
0.01076657,
0.194385,
0.03783695... |
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