title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Congenital heart disease in the first month of life. | During the years 1963--73, 276 children with congenital heart disease were admitted to this hospital during their first month of life. Ventricular septal defect was the most common cardiac anomaly and this lesion, together with transposition of the great arteries, comprised 35% of all cardiovascular malformations. Extr... | 472,669 | [
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Multiple pulmonary hamartomas; a case report and review of the literature. | Bilateral multiple hamartomas were found in a woman suspected of having metastatic malignancy of the lung. As extensive investigation for the primary tumour was unrevealing, a left exploratory thoracotomy and histological examination established the diagnosis. In view of the benign character of the tumours, local excis... | 472,676 | [
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Determination of inorganic fiber density in human lung tissue by scanning electron microscopy after low temperature ashing. | The concentration of asbestos fibers in lung tissue may give information about previous occupational asbestos exposure. A procedure for the preparation, quantification and identification of asbestos fibers in human tissue is presented in this report. The procedure is based on low-temperature plasma ashing of dry tissue... | 472,686 | [
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[Echocardiography. Advantages and limitations related to unidimensional and bidimensional technics in real time]. | Mode-M echocardiography is the most valuable non invasive technique in cardiology, but as a one-dimensional technique it displays the cardiac structure in an unfamiliar form without resemblance to the cardiac anatomy. Two-dimensional ultrasonic imaging of the heart overcomes this disadvantage. However, the definition o... | 472,691 | [
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[Experiences with an oral cocaine-morphine solution (Brompton mixture) in the treatment of severe pain in patients with neoplasms]. | One year's experience is reported in the treatment of terminally ill cancer patients with an oral solution of morphine and cocaine on a fixed schedule. 36 consecutive patients were treated for an average of 51 days. Excellent or good pain relief was achieved with 26 patients (72%). The initial mean daily dose of morphi... | 472,705 | [
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Memory load and event rate control sensitivity decrements in sustained attention. | The capacity to sustain attention at an efficient level deteriorates over time in discrimination and monitoring tasks. This "vigilance decrement" results from a decrement in perceptual sensitivity only if (i) target discrimination loads memory and (ii) stimulus events occur rapidly; otherwise, the decrement reflects te... | 472,714 | [
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Cerebral specialization, writing posture, and motor control of writing in left-handers. | It has been suggested that the inverted hand position of left-handers during writing indicates the left hemisphere of their brain is linguistically specialized and that the writing of these left-handers may be controlled via ipsilateral pathways. Electroencephalograph alpha asymmetry measures at central and parietal le... | 472,745 | [
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Pseudohermaphroditism in Ilyanassa obsoleta (Mollusca: Neogastropoda). | Field studies, a rearing and maintenance program, and a transfer experiment have shown that anomalous male traits found in some female Ilyanassa obsoleta are an expression of environmentally controlled psuedohermaphroditism. The particular pattern of pseudohermaphroditism discovered in this species has not been reporte... | 472,758 | [
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Systemic sarcoidosis presenting with a testicular nodule. | A patient presenting with the clinical and radiographic picture of pulmonary sarcoidosis was found to have a testicular nodule. Orchiectomy was done, and the pathologic specimen revealed only granulomatous inflammation. The involvement of the testis in sarcoidosis is reviewed, and recommendations are made regarding sur... | 472,795 | [
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Multifocal malignant melanoma of the esophagus. | We have described a case of primary melanoma of the esophagus in an asymptomatic patient. The tumor presented as a multinodular filling defect on a routine barium swallow. The distal esophagus and a proximal portion of the stomach were resected. The patient died ten days postoperatively of Klebsiella sepsis. Grossly, t... | 472,796 | [
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Adverse effects of pancuronium in patients with hemorrhagic shock. | Thirty-five patients with hemorrhagic shock had surgical repair of trauma to the great vessels using a ketamine-pancuronium-nitrous oxide sequence for anesthesia. The data of the cardiovascular and respiratory changes occurring during anesthesia and the operation were tabulated and subjected to multifactorial computer ... | 472,832 | [
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Sputum cytology in the diagnosis and treatment of lung cancer. | To evaluate the contribution of sputum cytology to the diagnosis and treatment of lung cancer, 918 cases of lung cancer were reviewed. Of 105 patients with positive sputum cytology, 93 had other invasive procedures to establish the cell type or stage or to attempt to cure the disease. In 12 patients the presence of pos... | 472,834 | [
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Histoplasmosis: clinical manifestations and surgical management. | In this retrospective study of 115 cases of histoplasmids, there were 66 male and 49 female patients ranging in age from 2 months to 79 years. The most common presenting symptoms were cough, chest pain, wheezing, weight loss, hemoptysis, and shortness of breath. Thirty-five patients (30%) were asymptomatic. Two patient... | 472,835 | [
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Cutaneous horns: a histopathologic study. | We report a series of 230 cutaneous horns, of which fewer than one fourth were frankly malignant. Actinic keratoses were the lesions most commonly found underlying cutaneous horns (37.39%). Cutaneous horns overlying a benign lichenoid keratosis, epidermolytic hyperkeratosis, trichilemmoma, an epidermal inclusion cyst, ... | 472,837 | [
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Lymphocyte toxicity in retinoblastoma. | Cytotoxicity can be used in the determination of patients with retinoblastoma. With further refinement, this type of test may become useful in aiding the physician in the detection of retinoblastoma. | 472,839 | [
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Screening for colorectal cancer. | A voluntary colorectal screening program was carried out in North Carolina to evaluate the public's willingness to perform a do-it-yourself bowel test, to educate the public on the importance of routine colorectal screening, and to assess the efficacy of a small-scale screening program in detecting colorectal cancer. A... | 472,841 | [
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Relationship between spray adhesives and congenital malformations. | Evidence from clinical impressions and laboratory slides that spray adhesive products could have a potentially dangerous mutagenic or teratogenic effect was first reported in 1973. However, similar laboratory slides observed by others revealed no significant difference between chromosomal slides of malformed infants an... | 472,845 | [
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Anterior reduction of interlocking facets in the lower cervical spine. | Twelve patients with locked facets of the lower cervical spine were surgically treated through an anterior approach. The interlocking was bilateral in 2 cases and unilateral in 10; in all patients, skull traction failed to obtain the reduction. The technique of anterior reduction is described, with particular attention... | 472,890 | [
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A krypton-81m generator for organ ventilation and perfusion investigations. | A sterile pyrogen-free generator for ultra-short half-life 81mKr has been developed. During initial loading, the binding efficiency of 81Rb is 90--99%. The count rate during perfusion is 3 x 10(5) counts per minute for a 1,9 GBq (50 mCi) 81Rb generator. The generator has been used for routine and special investigations... | 472,931 | [
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Folate metabolism and in vivo radiofolate binding in normal, folate-deficient and folate-saturated subjects. | After ingestion of 14C-CH3H4Pte Glu by folate-deficient and folate-saturated subjects, and 14C-CH3H4PteGlu as well as 3H-PteGlu by a normal control subject, the dialysis-resistant (bound) plasma radiofolate fraction appeared increased in folate saturation and decreased in folate deficiency (compared with normal folate ... | 472,932 | [
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The radiological features of primary pulmonary tuberculosis. | A very brief review is given of the pathology of primary pulmonary tuberculosis. Numerous characteristic, but not pathognomonic, radiological appearances of primary pulmonary tuberculosis are briefly described and some of them are illustrated. The final diagnosis, however, depends on correlating the radiological pictur... | 472,953 | [
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Yersinia enterocolitica biotype 1 in South Africa. | Two clinical isolates of Yersinia enterocolitica biotype 1, positive for indole and lecithinase production, xylose and salicin fermentation, and aesculin hydrolysis, are reported. One strain, serotype 0 6, was recovered from a healthy food handler, while the other, serotype 0 5, was associated with a diarrhoeal illness... | 472,961 | [
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Absorption of iron polymaltose and ferrous sulphate in rats and humans. A comparative study. | Free iron in the circulation in contrast to iron complexed with protein or carbohyrdate, is intensely toxic. The annual morbidity and mortality from accidental overdose with iron salts is significant and has directed attention to the evaluation of safer forms of therapy. Comparative studies between oral ferrous sulphat... | 472,964 | [
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Circulatory effects of endotoxin on unanesthetized sheep and the response to dopamine. | The cardiovascular effects of endotoxin in the unanesthetized chronically instrumented sheep were investigated. The observations were extended to include the response to intravenous infusions of dopamine to the same sheep at the height of endotoxin action. When the cardiovascular effects of endotoxin in the unanestheti... | 472,992 | [
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Hemodynamic studies before and after extended bypass grafts to the tibial and personeal arteries. | Thirty-ones limbs of 29 consecutive patients undergoing bypass grafts to the tibial or peroneal arteries were studied. Twenty-five limbs had ischemic rest pain with or without localized gangrene, and six had incapacitating claudication. The mean segmental pressure indices were upper thigh, 1.16 +/- 0.36; above knee, 0.... | 473,030 | [
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Results of subtotal parathyroidectomy for primary chief cell hyperplasia. | Analysis of the long-term results of subtotal parathyroidectomy in patients with primary chief cell hyperplasia provides evidence that refutes the recent assertion that such treatment is often ineffective. With the use of rigid criteria, 55 patients with unequivocal chief cell hyperplasia were culled from 1,576 patient... | 473,032 | [
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Teratogenic effects of nickel chloride on embryonic mice and its transfer to embryonic mice. | Administration of nickel chloride to the pregnant mice on the seventh to eleventh day of their gestational period, resulted in significant embryotoxic effects in terms of an increased resorption rate, a decreased fetal weight, delay in skeletal ossification and high incidence of malformation. Among the cases of fetal m... | 473,066 | [
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An aberrant nucleus in the telencephalon following administration of ENU during neuroembryogenesis. | Administration of ENU to rats during embryonic development caused the emergence of aberrant nuclei in the dorsal telencephalon. They were located in the corpus callosum, and were composed of pyramidal and stellate neurons. This suggested that the aberrant nuclei arose out of the neurons of cerebral cortex that had fail... | 473,069 | [
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Prenatal ethanol exposure in mice: teratogenic effects. | C57BL/6J mice were fed a liquid diet in which 17, 25, or 30% of the calories were derived from ethanol from the fifth through the tenth day of gestation. Control mice were fed lab chow or pair-fed identical diets, except that sucrose substituted isocalorically for ethanol. At term the fetuses were removed and, followin... | 473,082 | [
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Plastic casts of embryonic respiratory and cardiovascular system: a technique. | This report describes a technique for producing plastic casts of the cardiovascular and respiratory systems of the chick embryo at Stage 36 or older. For casts of the cardiovascular system, polymerization compound is injected in the right ventricle filling the heart, venous, and arterial system. A two stage injection p... | 473,087 | [
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Organ culture of adult amphibian heart: a fine structural analysis. | Pieces of hearts from adult newts were cultured up to 2 months. Within 7 days of culture, approximately 37% of the cardiac explants were attached to the substrate and more than 33% of the attached explants and approximately 15% of the unattached explants established pulsation rates ranging from 3 to 67 beats/min. The c... | 473,159 | [
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0.1850804,
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Post natal side effects in rats induced by hypolipidaemic treatment during pregnancy. | Maternal, foetal and peri- and post-natal toxicity studies of a hypolipidaemic agent, 2-[p-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl propionic acid (WIN 35833), were performed on different animal species during animal evaluation of this new drug. In teratology studies in rats, mice and rabbits, no adverse effects were... | 473,221 | [
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... |
Chromium-induced hyperglycemia in the rat. | The acute administration of chromium chloride (Cr) produces hyperglycemia in rats. Adrenalectomy prevents the hyperglycemic effect but not the glucose intolerance. Subacute exposure of rats to Cr for 7--23 days does not change the resting blood glucose nor is there an acute or subacute effect on tolerance to glucose lo... | 473,224 | [
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0.377278... |
Absorption, distribution and metabolism of propyl anthranilate. | Analysis of the gut contents of rats killed at intervals after dosage with propyl anthranilate or anthranilic acid suggested that both acid and ester were absorbed rapidly; the chief site of absorption was the stomach. Not more than a trace of the ester was hydrolysed in the stomach but of the dosed ester detected in t... | 473,227 | [
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[Electroencephalographic findings in the late stage after CNS-irradiation for malignant neoplasms in children (author's transl)]. | Of forty children having undergone two or more years ago an irradiation of the brain case with cobalt-60 delivering doses between 1800 and 2400 R TD (n = 20) or a dose above 3500 R TD (n = 20), as a matter of fact ten presented pathological EEG findings which, however, may be interpreted as genetically determined chara... | 473,253 | [
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0... |
Black suicide in the seventies: current trends. | In the most recent decade, the suicide rate among young blacks has risen to the point where it is nearly as high as that of their white peers. The data in this analysis reflect the striking contrast in age distribution in the suicide patterns of whites and blacks. Whereas white suicide increases in direct relation with... | 473,285 | [
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Malaria and haemoglobin A2 levels in northern Liberia. | The influence of malaria on HbA2 levels was investigated in two groups of children aged two to nine years from the Mano tribe of northern Liberia. One group, 174 children living in a town where there is malaria control, had a parasite rate of 6.5%, only a few having palpable spleens, but 282 children living in an area ... | 473,309 | [
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0.2562664,
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A regional blood management system with prescheduled deliveries. | The prescheduling of blood deliveries from regional blood centers can improve blood availability at all transfusion services while reducing outdating, delivery costs and inventories maintained at region blood centers. A procedure for determining optimal distribution policies that maintain the highest possible blood ava... | 473,347 | [
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[Age peculiarities in the content of nucleic acids, collagen (as oxyproline) and other proteins in rat skin and lung tissues]. | It is established that in old animals, as compared to the young ones, the content of nucleic acids, the total content of protein and the content of the peptide-bound oxyproline in the collagen soluble fractions in the skin and lungs tissues decrease, whereas the content of peptide-bound oxyproline in the insoluble coll... | 473,393 | [
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0.2483971,
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Serum xanthine oxidase in bladder carcinoma. | This study comprises of 48 normal men as control group and 49 patients with various stages of bladder carcinoma. Serum xanthine oxidase and uric acid levels were determined. Assessment in terms of changes of the enzyme xanthine oxidase was carried out prior and after surgery as a short-term follow-up. There was a signi... | 473,429 | [
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[The conservative therapy of urolithiasis (author's transl)]. | Some common conservative treating methods of urolithiasis are critically discussed. Based on physico-chemical relationships of solubility and cristallisation of stone-forming compounds our own methods of conservative treatment of urolithiasis is presented. | 473,452 | [
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Oncocytoma of kidney. | Two cases of oncocytoma of the kidney are presented. The clinical and pathologic characteristics of this rare tumor are described and compared with those of renal cell carcinoma. | 473,471 | [
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The pregnant Syrian hamster as a model to study intravascular trophoblasts and associated maternal blood vessel changes. | In pregnant Syrian hamsters (Mesocricetus auratus) used as an animal model for studying the migration of fetal trophoblasts and the associated changes in maternal blood vessels, intravascular trophoblasts migrated well beyond the blood vessels of the uterus and into the vessels of the mesometrium. They migrated beyond ... | 473,486 | [
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Mesotheliomas and proliferative lesions of the testicular mesothelium produced in Fischer, Sprague-Dawley and Buffalo rats by methyl(acetoxymethyl)nitrosamine (DMN-OAc). | A single intraperitoneal dose of methyl(acetoxymethyl)nitrosamine (13 mg/kg body weight) given to 78 5-week-old male rats induced 25 mesotheliomas; two mesotheliomas were found in 67 control rats. All mesotheliomas arose from the peritesticular mesothelium and had a typical microscopic appearance of branching papillary... | 473,488 | [
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An outbreak of ringworm in a group of young cattle. | In an outbreak of ringworm, 30 out of 32 bull calves being reared intensively for beef showed infection. Weekly observations were made from their arrival at the farm at about one week old until slaughter at approximately 10 1/2 to 12 months of age. The outbreak lasted for 33 weeks and appeared to originate from two ani... | 473,565 | [
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[Effect of the total flavonoids from red clover and chick-pea on the lipid content in the blood and liver of rats]. | Total flavonoids from clover red and nut, containing isoflavones, decreased the content of cholesterol and triglycerides in intact rats, inhibited the development of hyperlipidemia, caused by Triton WR-1339, prevented accumulation of triglycerides in rat liver and blood caused by ethanol administration. The flavonoids ... | 473,686 | [
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... |
[The evaluation of patients with urinary calculi discloses disturbances of metabolism in 75% of all cases (author's transl)]. | The causes of, and physiopathological factors underlying the most common metabolic disorders implicated in the formation of renal stones are reviewed. These include hypercalciuria, hyperoxaluria, renal tubular acidosis, cystinuria and disturbances of purine metabolism. Apart from metabolic disorders the risk of stone f... | 473,769 | [
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[Analysis of respiration in the sleeping infant. Possible relationship to sudden infant death]. | Preliminary results are indicating, that disorders of the control of respiration during sleep may be an explanation of the sudden infant death syndrome (SIDS). It should be possible to determine individual risk factors for SIDS by means of improved and extended studies, leading finally to a successful prevention of inf... | 473,776 | [
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[Differential diagnosis of interstitial lung diseases]. | It is reported on the different forms of the interstitial pulmonary diseases. Apart from the clinical examination the establishment of the professional and hobby anamnesis play an important part for the differential diagnosis. Allergologic and immunologic examination methods may contribute to the etiologic clarificatio... | 473,817 | [
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... |
[Adjuvant DNCB immunotherapy in malignant melanoma]. | Report on the application of a dinitrochlorobenzene ointment of 61 postoperative melanoma patients exhibiting clinical stages I and II. After contact sensitization the erythemogenic threshold concentrations of DNCB were mostly found in the range of 0,05% and 0,1%. Patients with reactions at low concentrations of 0,01% ... | 473,840 | [
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-0.0906937... |
[Long-time follow-up scintigraphy with 99m Tc pyrophosphate after myocardial infarction (author's transl)]. | Follow-up scintigraphies with 99m Tc pyrophosphate 3--4 weeks and 6--12 months after a myocardial infarction revealed the possibility of persisting a myocardial tracer activity in cases in which reinfarction can be excluded. There was a relation between the persistence of the tracer activity and the pressure in the pul... | 473,846 | [
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[The applicability of systolic time intervals in patients before and after aortic valve replacement (author's transl)]. | In order to evaluate the systolic time intervals (STI) for characterizing the left ventricular pump function and the clinical course in patients with aortic valve disease, 35 patients with aortic stenosis (AS) and 25 patients with aortic insufficiency (AI class III or IV (NYHA) were studied before and 1 year after valv... | 473,848 | [
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0... |
[EEG correlation and cortical neurons spike activity during elaboration of a defensive conditioned reflex]. | Elaboration of electro-defensive conditioned reflex to light in rabbits has shown, that the values of summary cross-correlation coefficients between EEG and impulse activity of cortical neurones do not change significantly as compared to the control. In these conditions does not change either the part of the neurones t... | 473,907 | [
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0.0474... |
[The value of morphology in the diagnosis of chronic polyarthritis]. | The clinician's question concerning the value of morphological findings in diagnosis of rheumatoid arthritis is answered by the pathologist. After a short discussion of clinical problems and the ARA-criteria, at first the diagnostic importance of synovial cytology in RA is dealt with. The patient's history, biopsy tech... | 473,927 | [
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[The therapeutic effect of glycosaminoglycan polysulfate (Arteparon) in arthroses depending on the mode of administration (intraarticular or intramuscular)]. | The effect of GAGPS (Arteparon) was investigated on patients with osteoarthritis of hip-joints in dependence from the method of application. By that way 50 patients got each 6 injections with 125 mg/0,5 ml Arteparon intraarticular and 50 patients each 10 injections with 125 mg/0,5 ml Arteparon intramuscular. We have do... | 473,929 | [
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Associative symbiosis of Azotobacter chroococcum and higher plants. | The association between a selected strain of Azotobacter chroococcum and seven plants was investigated in water cultures under sterile conditions. Azotobacter population progressively increased in the nutrient solution and on the rhizoplane. Microbial propagation depends on the type of plant, being much higher in prese... | 473,964 | [
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0.3174236,
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The effect of temperature and age of strains of Fusarium oxysporum on its enzymatic activity. | The activities of pectin-methyl-esterase, polygalacturonase, cellulase, amylase, saccharase, and protease of strains of Fusarium oxysporum (Schlecht.) f.sp. pisi (Linford) were studied. The selected strains showed different symptoms and different degrees of pathogenicity on the host plant. The measurements were perform... | 473,966 | [
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... |
[RNAse activity as an indirect index of the enterotoxigenicity of staphylococci]. | On the basis of investigations carried out there was revealed a direct relationship between the capacity of staphylococci to produce enterotoxin and the extent of their RNA-ase activity. The activity of RNA-ase can serve as a significant indirect sign pointing to the enterotoxigenicity of staphylococcus. | 474,003 | [
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... |
[Pain phenomenon in the structure of a seizure as a symptom of subcortical epilepsy]. | A long-term dynamic study of epilepsy permitted one to distinguish a group of patients (21), who had undergone cortical surgical operations in the sensomotor area. In this group of patients the epileptical seizures were not only arrested, but preserved their previous structure. In all observations, the attack included ... | 474,017 | [
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... |
Study on the reproducibility of human prolactin response to sulpiride, benserazide, insulin hypoglycaemia and arginine infusion. | In order to evaluate the spontaneous variability of prolactin (PRL) release in response to various stimuli applied repeatedly on different occasions, groups of 5 to 12 subjects each underwent consecutive identical tests with one of the following stimuli applied at 3-6 days' intervals: sulpiride (100 mg im), benserazide... | 474,034 | [
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0.06197... |
[Experimental evidence for motoric rehabilitation in lymphoedema (author's transl)]. | The authors distinguish three modalities of lymphtransport in lymphoedema. 1. Enhanced evacuation by existing lymphatics. 2. Enhanced evacuation by regenerated lymphatics. 3. Enhanced evacuation by lympho-lymphatic anastomoses. Experiments with 500 white mice indicate that the resorption of lymphoedema is increased by ... | 474,032 | [
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0.1... |
Left chylothorax complicating a translumbar aortography. | The authors report a case of left chylothorax after a translumbar aortography, successfully managed by conservative means. As far as they known 16 similar cases are described. They review the literature on this subject. | 474,030 | [
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0.0367... |
[Treatment of patients with hemophilia A having antibodies to factor VIII]. | Four haemophiliacs with antibodies to factor VIII were treated on 7 occasions with fraction FEIBA. Satisfactory clinical results were achieved in patients receiving large doses of the preparation (63-105 units/kg). The administration of fraction FEIBA produced shortening of the whole blood clotting time but there was o... | 474,044 | [
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0.04635558,
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Asymmetric retinitis pigmentosa, luetic retinopathy and the question of unilateral retinitis pigmentosa. | A seropositive patient with the fundus appearance of monocular luetic retinopathy is presented. Electrophysiologically, this patient shows a late-onset form of progressive tapetoretinal degeneration (retinitis pigmentosa) presenting in an extremely asymmetric manner. The differential diagnosis of luetic and other infla... | 474,081 | [
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Incorporation of radioactive calcium into otolithic membranes of the guinea pig after aminoglycoside treatment. | The influence of neomycin and streptomycin on the calcium metabolism of the otolithic membranes was investigated in the guinea pig. After chronic treatment with either drug, animals were injected intraperitoneally with radioactive calcium. Retention of calcium in the serum was unaffected by drug treatment, as was the i... | 474,121 | [
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0... |
Ochratoxin A-induced mycotoxic porcine nephropathy: alterations in enzyme activity in tubular cells. | Mycotoxic porcine nephropathy was induced by p.o. administration of crystalline ochratoxin A for periods of 5 days, 3 months and 2 years. Enzyme activities of the renal tissue were studied histochemically. These were NADH-tetrazolium reductase, NADPH-tetrazolium reductase, lactate dehydrogenase, isocitrate dehydrogenas... | 474,126 | [
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0.0... |
Ascitic fluid modifying the distribution of sulphafurazole in rats with intestinal occlusion. | In order to confirm our previous findings of increased sulphafurazole (sulfisoxazole, SF) inactivation by intestinal occlusion, SF was given intravenously 20 mg/kg to rats with a low small intestinal occlusion and to sham-operated controls 40-45 hours after the operation. Occlusion did not cause major changes in the di... | 474,157 | [
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... |
Glomerulonephritis and exposure to organic solvents. A case-control study. | Fifty patients with biopsy-proven glomerulonephritis and 100 sex- and age-matched controls (50 patients each with non-glomerular renal disease or acute appendicitis) were asked by questionnaire and a telephone interview whether they had been exposed to organic solvents. The questioning and the evaluation of the exposur... | 474,184 | [
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0.33... |
Renal function and plasma aldosterone during acute lithium intoxication. | Studies on plasma aldosterone, total serum protein, electrolytes, osmolal concentrations in serum and urine, creatinine, lithium and osmolal clearances were carried out on 14 patients suffering from lithium intoxication. The determinations were done on samples obtained on admission and during the following twelve days ... | 474,187 | [
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0.0627... |
Inhibition of cell division and stimulation of progesterone receptor synthesis in rat oestrogen target tissues by non-steroidal antioestrogens. | Recent studies from this laboratory have demonstrated oestradiol-oestrogen receptors associated with the nuclear compartment of the rat uterine cell will initiate protein synthesis, as evidenced by a rise in progesterone receptor concentrations, and cell division whereas the anti-oestrogen - oestrogen receptor complex ... | 474,275 | [
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... |
Electrophysiological studies on the effects of the neurotoxin apamin on cultured neurons. | Primary cultures of rat embryonic central nervous system were grown for 3 to 4 weeks in vitro. Impalement of neurons by means of high-resistance glass pipettes revealed that firing of action potentials could either be elicited by application of short square pulses or occurred spontaneously. The presence of the neurotox... | 474,302 | [
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0.4652904,
0.1404788,
0.023682... |
A comparison of the carrageenan edema test and ultraviolet light-induced erythema test as predictors of the clinical dose in rheumatoid arthritis. | Twelve non-steroidal anti-inflammatory agents (NSAI's) and one steroidal anti-inflammatory agent, dexamethasone, were examined in the carrageenan edema test (CET) in the rat and in the ultraviolet light-induced erythema test (UVE) in the guinea pig to evaluate the correlation between those models of inflammation and th... | 474,303 | [
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Olfaction and muscle activity: an EMG pilot study. | The therapeutic significance of limbic system structures in general, and olfactory structures specifically, has been described by Fox, Ayres, Moore, and Farber in their professional presentations and publications. No data have yet been provided to substantiate claims of the effects of olfactory stimulation on muscle ac... | 474,334 | [
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The association of amorphous mineral deposits with the plasma membrane of pre- and young odontoblasts and their relationship to the origin of dentinal matrix vesicles in rat incisor teeth. | Young and preodontoblasts and matrix vesicles which occur in the presecretory region of incisor teeth of growing rats were examined in stained and unstained ultrathin sections in order to characterize sites involved in the initial mineralization of dentin. Common to pre- and young odontoblasts in the presecretory regio... | 474,446 | [
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Effects of a vigorous walking program on body composition, and carbohydrate and lipid metabolism of obese young men. | With no attempt made to influence their diet, six sedentary obese men ages 19 to 31 completed 16 weeks of vigorous walking 90 min, 5 days/week, on a treadmill at up to 3.2 mph on a 10% grade, expending about 1100 kcal per session. Body composition studies indicated a loss of 5.9 kg of body fat and a gain of 0.2 kg of l... | 474,467 | [
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Adipose tissue cellularity in obese nondiabetic men in an urbanized Pacific island (Polynesian) population. | In a Pacific island (Polynesian) population exposed to Westernized food-stuffs and sedentary life during adulthood, the fat cell size in the gluteal region in obese men was 71% higher than in age-matched nonobese controls. Rough estimations of body fat from anthropometric measurements suggest that the obesity of these ... | 474,468 | [
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... |
Bile acid metabolism in ascorbic acid-deficient guinea pigs. | Sterol balance techniques have been used to determine the effect of short-term ascorbic acid (AA) deprivation on bile acid excretion in the guinea pig. The effects of a brief (2-week) AA deficiency on bile acid pool sizes and the activity of the rate controlling enzyme in bile acid biosynthesis have been determined. It... | 474,473 | [
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Dietary fiber and nutrient intake in Crohn's disease. | The mean daily intake of dietary fiber, sugar, starch, fat, protein, and total energy was determined in 35 patients with Crohn's disease and 70 normal controls by obtaining individual dietary histories. For each patient with Crohn's disease there two controls, matched for age, sex, and socioeconomic background. In the ... | 474,481 | [
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0.4162474,
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A precision study of a photo-optical factor VIII assay technic. | Various methods of factor VIII analysis with a wide range of accuracies as confirmed by calculated coefficients of variation have been devised. The authors report a technic of factor VIII assay using a photo-optical clot-detection instrument with commercially available sources of factor VIII-deficient plasma and lyophi... | 474,495 | [
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0... |
An investigation of coronary heart disease in families. The Framingham offspring study. | The Framingham Heart Study (FHS) was started in 1948 as a prospective investigation of cardiovascular disease in a cohort of adult men and women. Continuous surveillance of this sample of 5209 subjects has been maintained through biennial physical examinations. In 1971 examinations were begun on the children of the FHS... | 474,565 | [
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The use of correlation and regression in the analysis of family resemblance. | The use of correlation and regression as applied to the analysis of family resemblance is discussed. The application of these statistical techniques to family data is not routine because the number of siblings per family is in general variable. Topics dealt with include estimation of sib-sib (intraclass) correlation, p... | 474,569 | [
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Marked hypodiploidy in a case of acute undifferentiated leukemia. | A-29-year-old white man with acute undifferentiated leukemia had bone marrow cells with predominantly 42 chromosomes including several rearrangements. Following a brief induced "complete" remission, during which normal chromosomes were observed, bone marrow cells with 42 chromosomes but a different karyotype than befor... | 474,573 | [
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Immunologically-mediated acute renal failure of nonglomerular origin in the course of systemic lupus erythematosus [SLE]. Report of two cases. | Acute anuric renal failure was observed in two patients with systemic lupus erythematosus (SLE) during the clinical and serologic active phase of the disease. Renal biopsies, performed during the acute episodes, showed only mild and focal mesangial cell proliferation without deposits. In contrast, tubulointerstitial le... | 474,602 | [
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A ladder curriculum in clinical microbiology. | A continuum of four microbiology courses for medical technology majors has been developed by the Medical Laboratory Science Program at Northeastern University. Using a system approach to curriculum design, the academic and clinical faculty identified career-entry capabilities, delineated appropriate subject content, an... | 474,608 | [
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0.07287978,
0.1196852,
0.09894936,
-0.05155205,
... |
H-Y antigen in 46,XY pure testicular dysgenesis. | Clinical, cytogenetic, pathologic, and histocompatibility-Y (H-Y) antigen studies were performed on a phenotype female with primary amenorrhea and streak gonads. Pathological examination of tissues removed at total hysterectomy and bilateral salpinog-gonadectomy showed gonadoblastoma and dysgerminoma of left streak. A ... | 474,628 | [
-0.05574826,
0.114554,
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0.09476769,
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0.2197391,
0.1505876,
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... |
An examination of the spectrum of anatomic defects and variations found in eight cases of trisomy 13. | We report the anatomic variations found in four additional cases of trisomy 13. Data from these and four previous cases [Colacino and Pettersen, 1978] are utilized to define a muscle phenotype. Previously unreported defects include the bilateral presence of cervical ribs and the bilateral absence of 12th thoracic ribs ... | 474,630 | [
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0.2008911,
0.08595677,
-0.0867... |
Gerodermia osteodysplastica hereditaria: report of three affected brothers and literature review. | Gerodermia osteodysplastica hereditaria was diagnosed in three Mexican brothers 6, 7, and 8 years old, respectively, who had the distinct facial appearance with sagging cheeks, premature wrinkling of the skin of face, abdomen, and dorsum of hands and feet; malocclusion, span greater than height; hyperextensibility; win... | 474,638 | [
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0.002366365,
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0.23306,
0.0896994,
-0.08034411... |
Serial relaxin concentrations in human pregnancy. | Relaxin is a peptide hormone produced by the corpus luteum during pregnancy in human beings. There are no extraluteal sites of production of relaxin in women. By means of a heterologous porcine radioimmunoassay, serial serum relaxin concentrations were determined in three women throughout pregnancy and into labor. All ... | 474,660 | [
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0.03905149,
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0.104867,
0.4371696,
0.01453899... |
Activity and work during pregnancy and the postpartum period: a cross-cultural study of 202 societies. | Cross-cultural information on 202 traditional societies was perused for data on customs surrounding the expected work load of pregnant and postpartum women. The most common single pattern of work activity during pregnancy was that of continuing full duties until the onset of labor. A bare majority of societies did enco... | 474,666 | [
0.1206245,
0.1117762,
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0.1199598,
0.4147,
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... |
Vessel density in endometrium of women with and without intrauterine contraceptive devices: a morphometric evaluation. | Increased vascularity was found in the endometrial functionalis in uteri of women wearing intrauterine contraceptive devices (IUDs) as compared to uteri of women without IUDs (control subjects). Vessel concentration was highest in endometrial tissue adjacent to that tissue which was depressed by the IUD. In control tis... | 474,672 | [
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0.3062866,
0.1820827,
0.1551491,
0.2561851,
0.1169172,
0.5565671,
0.2038188,
0.0879... |
HLA antigens and acute angle-closure glaucoma. | Thirty-five unrelated white patients with acute angle-closure glaucoma and 126 previously healthy unrelated white cadaveric kidney donors were typed for histocompatibility (HLA) antigens. Upon Z-ratio proportionality testing, no association between acute angle closure glaucoma and any specific HLA antigen was noted. | 474,693 | [
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0.09166703,
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0.2776954,
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0.03316697,
0.02913922,
-0.17060... |
The effects of intravitreal irrigation during vitrectomy on the electroretinogram. | Intravitreal irrigation with Balanced Salt Solution Plus (BSS Plus) produced less decrease in b-wave amplitude than either normal saline solution or Balanced Salt Solution. BSS Plus was more suitable for intravitreal irrigation because it contained the appropriate bicarbonate, pH, and ionic composition necessary for ma... | 474,695 | [
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0.05061333,
0.3947774,
0.03235536,
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0.04868066,
0.108788,... |
Increased myocardial catalase in rats fed ethanol. | The effects of chronic intake of dietary ethanol upon catalase, an enzyme capable of metabolizing ethanol, as well as upon myocardial morphology and hemodynamics, were studied in the rat. Ethanol, comprising 36% of dietary calories, administered to rats for 5 weeks, was associated with increased myocardial catalase of ... | 474,705 | [
-0.01057731,
0.2579444,
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0.2693751,
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0.1762123,
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0.1542509,
0.01250167,
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0.3361964,
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0.3556567,
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0.02209397,
0.2582375,
-0.04404612,
0.2983188,
-0.08271705,... |
The Chédiak-Higashi syndrome: ring-shaped lysomomes in circulating monocytes. | The giant inclusion anomaly of leukocytes from three patients with the Chédiak-Higashi syndrome (CHS) has been reexamined by the ultrastructural and cytochemical techniques placing emphasis on the monocyte. Contrary to previous assumptions that all CHS leukocytes shared a common form of giant granule with similar mecha... | 474,718 | [
-0.004894947,
0.07928856,
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0.1945748,
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0.1865172,
0.2454473,
0.03559698,
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0.3257419,
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0.06873776,
-0.3703499,
-0.0491995,
0.1393923,
0.02275556,
0.1587746,
0.2603529,
0.120328... |
Gastric pacemaker rhythm in conscious dog. | The pacemaker rhythm in the stomach of six healthy conscious dogs was studied by means of the measurement of sequential electrical control activity (ECA) intervals. Only the rhythm originating in the normal pacemake area was studied. An electrical response activity (ERA) score was used to assess contractile activity. W... | 474,754 | [
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0.1781704,
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0.09978069,
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0.1702249,
0.07403719,
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0.1158921,
-0.07767095,
0.2139713,
-0.... |
Acute and chronic effects of vasopressin on blood pressure, electrolytes, and fluid volumes. | Physiological levels of arginine vasopressin (AVP) were continuously infused 24 h/day into six dogs for periods ranging from 7 to 34 days. The acute and chronic responses of the mean arterial pressure (MAP), body fluid volumes, renal function indices, plasma electrolyte concentrations, plasma renin activity, and urinar... | 474,764 | [
-0.5080828,
0.08923538,
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0.261548,
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0.4416246,
0.1157546,
-0.4001016,
-0.1481224,
-0.007871483,
-0.23445... |
Forum on osmosis. II. A criticism of "solvent tension" in osmosis. | Concepts about the liquid state that are inconsistent with the facts are noted, and solvent under tension is one of them. Osmosis is not present in a solution: it is a process in the presence of a semipermeable membrane that can be quantified by the operation of applying a hydrostatic pressure. The classical derivation... | 474,781 | [
-0.2189491,
-0.5788651,
-0.2437605,
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0.2661228,
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0.008513716,
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0.02620443,
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0.331244,
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0.009381915,
-0.2711079,
-0.1446845,
0.2846644,
0.08865942,
-0.1014... |
Computer simulation of metabolism in pyruvate-perfused rat heart. IV. Model behavior. | The behavior of a computer model of energy metabolism was determined for perfused rat hearts utilizing pyruvate as sole exogenous fuel and subjected to a rapid increase in work load. Computer-generated metabolite profiles, which are solutions of the differential equations for 1 min elapsed time, closely match 12 experi... | 474,789 | [
-0.3215224,
0.1033134,
-0.5055289,
0.2853742,
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0.1438154,
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0.06617662,
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0.0271,
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0.1139037,
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0.08537678,
-0.008985584,
0.0526563,
0.3651444,
-0.1135636,
0.15... |
Adults' reactions to the death of a parent: a preliminary study. | The authors conducted a systematic psychodynamic investigation directed explicitly toward the bereavement reactions of people who have lost a parent during their adult life. They conducted a single in-depth interview of 14 people with a mean age of 32.4 years who had experienced the death of a parent in the last 3--20 ... | 474,802 | [
-0.483767,
-0.06234987,
-0.05207901,
0.03484739,
0.2735211,
-0.03086351,
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-0.05821011,
0.3795143,
0.1272663,
0.2345702,
0.3140089,
0.4419127,
0.01009... |
The risk of low birthweight. | Descriptive analyses of birthweight for single live births in the United States during 1974, using birth certificate information, show that several factors are associated with a high incidence of low birthweight babies. Multivariate analyses were performed to determine correlates of low birthweight. When other factors ... | 474,844 | [
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0.02375024,
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0.3344797,
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0.005920205,
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0.09285335,
0.04948395,
0.08546258,
-0.1744321,
0.2455783,
0.1207257,
-0.060554... |
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