title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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[Antisociality and school failure as judged by elementary school teachers (author's transl)]. | 126 elementary school teachers were interviewed in respect to their concepts of school failure and antisociality. According to their opinions antisociality finds its expression especially in the following behaviour: delinquent and/or destructive actions against others or the state, deliberate disturbance of social peac... | 478,737 | [
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Transcatheter electrocoagulation: experimental evaluation of the anode. | Transcatheter electrocoagulation using direct current has been shown to be an effective method for vessel occlusion. To date, the stainless steel anode has not been entirely satisfactory. Thus, an evaluation of bipolar platinum electrodes and a comparison of monopolar platinum and stainless steel electrodes have been p... | 478,795 | [
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Metrizamide, the ideal radiopaque filling material for detachable silicone balloon embolization. | Porcine visceral and extremity arteries were embolized with detachable silastic balloons; 10 balloons were filled with isoosmolar metrizamide, five were filled with 30% meglumine-sodium diatrizoate and five were filled with 3:1 mixtures of blood and 76% meglumine-sodium diatrizoate. Follow-up radiographs were obtained ... | 478,793 | [
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Bone mineral analysis using single-energy computed tomography. | We present a new method for evaluating in vivo changes in bone mineralization in the peripheral skeleton, using computed tomography (CT). A set of bone mineralization indices are generated from numerous CT images of the patient's distal radius. The cross-sectional anatomy displayed by the CT scan allows for separate ev... | 478,800 | [
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Steady-state serum quinidine concentration: role in prophylactic therapy following acute myocardial infarction. | Steady-state serum quinidine concentrations were monitored in 24 patients with acute myocardial infarction who were on a 1,300-mg daily dosing regimen. Mean serum concentrations spanned the therapeutic range, from 2 to 6 microgram/ml in 21 patients. In no patient was the level of 7 microgram/ml exceeded. Mean levels we... | 478,822 | [
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Investigation of crystallosis of the kidney by means of polarization, scanning, transmission and high-voltage electron microscopy. | This report deals with the investigation of renal crystallosis in the autopsy tissue of a fatal human case of ethylene glycol poisoning. A previously healthy 22-year-old man consumed about one liter of Prestone antifreeze, which contains 95% by weight of ethylene glycol. He died in coma 48 h later with clinical evidenc... | 478,828 | [
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[Paratibial symetric muscle hernias]. | Two cases of uncommon tumor-like alterations on the lower legs are discussed to be related to peizongenic pedal papules and diagnosed as myoceles. | 478,860 | [
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Resolution of a gold latensification-elon ascorbic acid developer for Ilford L4 emulsion. | The electron-microscopical autoradiographical resolution of a gold latensification-elon ascorbic acid (GEA) developer for Ilford L4 emulsion was determined experimentally, using radioactive line sources of tritiated albumin (Heijnen and Geuze, 1977). For sections with a thickness of 62 nm (SD +/- 11), which were covere... | 478,993 | [
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Detection of Salmonella in onion and garlic powders: collaborative study. | The relative efficiency of trypticase soy broth with added 0.5% K2SO3 and lactose broth as pre-enrichment media for recovering Salmonella from onion powder and garlic powder was collaboratively studied. For each spice, 13 collaborators each received 5 duplicate samples; 4 of the 5 replicate samples were inoculated with... | 479,071 | [
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DC polarography of cephradine and its application to capsules. | A polarographic method has been developed for the quantitative analysis of cephradine and its dosage forms. Direct determinations on capsules are carried out; excipients and coloring matter do not interfere in the determination. The electroactive product is formed by acidic hydrolysis with 5.0N HCl and heating at 80 de... | 479,077 | [
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Determination of amprolium in feeds: collaborative study. | The official final action method, 42.028--42.032, for determining amprolium in feeds was modified by a change in the preparation of aluminum oxide for chromatography. A premix containing 0.5% amprolium was collaboratively studied by the modified and the official methods. Compared with the modified method, 87.7% of the ... | 479,090 | [
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Cognitive impairment and treatment outcome with alcoholics: preliminary findings. | The relationship of cognitive impairment to treatment outcome in a sample of male alcoholics (N = 30) was explored. The Brain-Age Quotient (BAQ), an index of problem solving and adaptive abilities based on a battery of neuropsychological tests, was used as the summary measure of cognitive impairment. High BAQ scores we... | 479,116 | [
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Crystallization and preliminary crystallographic data of chicken gizzard G-actin . DNase I complex and Physarum G-actin . DNase I complex. | Smooth muscle G-actin from chicken gizzard and Physarum plasmodium G-actin both interact with DNase I and form 1 : 1 complexes. These complexes were crystallized by using polyethylene glycol 6000 as a precipitant. Both crystals belong to the same orthorhombic space group P2(1)2(1)2(1). The cell dimensions of chicken gi... | 479,124 | [
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Isolation and amino acid sequences of proline-rich peptides of human whole saliva. | Three basic peptides with extremely high proline contents were isolated from human whole saliva. The amino acid sequences of two of these proline-rich peptides comprising 57 and 38 residues were determined by conventional methods. The sequence suggested that the smaller peptide was derived from the larger one and also ... | 479,131 | [
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Characteristics of D-leucine uptake by mouse Ehrlich ascites tumor cells. | In a previous paper, we reported that various D-amino acids were taken up several times more effectively than the corresponding L-isomers into several tumors tested in vivo. In order to investigate this further, the in vitro uptake of D-[14C]leucine by Ehrlich ascites tumor cells was investigated in comparison with tha... | 479,135 | [
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Molecular arrangement of troponin-T in the thin filament. | 1. Chymotrypsin cleaved troponin-T of skeletal muscle into two subfragments, i.e., troponin-T1 and -T2, each of which could be isolated by the use of DEAE-Sephadex. Troponin-T1 was a single subfragment with a molecular weight of 26,000 (chicken) or 22,000 (rabbit) daltons. Troponin-T2 consisted of two subfragments with... | 479,140 | [
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Adenine nucleotide degradation during energy depletion in human lymphoblasts. Adenosine accumulation and adenylate energy charge correlation. | Adenine nucleotide breakdown to nucleosides and purine bases was measured in cultures of human lymphoblastoid cells following: 1) the inhibition of oxidative phosphorylation in the absence of glucose or 2) the addition of 2-deoxyglucose. A mutant cell line, deficient in adenosine kinase, in the presence of an adenosine... | 479,172 | [
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The insulin-like effect of hydrogen peroxide on pathways of lipid synthesis in rat adipocytes. | In addition to the well known insulin-like effects of certain concentrations of H2O2 on glucose transport and oxidation in isolated rat adipocytes, the present work demonstrates that lipid synthesis from glucose is also enhanced over a narrow range of H2O2 concentrations (0.15 to 0.5 mM) added to the incubation medium.... | 479,177 | [
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Characteristics of tissue growth into Proplast and porous polyethylene implants in bone. | (1) Bone does not form within internal pores of undistorted Proplast implants because of the small interconnecting pore size of the material; (2) the nonosseous, fibrous tissue which exists in the pores of Proplast implants in bone is not attached to the surrounding bone (i.e., Sharpey's fibers are not present). The lo... | 479,215 | [
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Degradation resistance of some candidate composite biomaterials. | The degradation resistance of matrix, fiber and composite systems which we have been studying as candidate orthopedic materials has been examined in two appropriate environments. Both resistance to steam sterilization in an autoclave environment and resistance to a simulated physiologic solution have been studied. In t... | 479,222 | [
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Serratus anterior paralysis in the young athlete. | Ten cases of isolated, complete paralysis of the serratus anterior muscle were diagnosed in young athletes during a three-year period. One patient had recurrent partial paralysis of the serratus anterior muscle, the first such case reported. From studies on cadavera and clinical observations, we concluded that paralysi... | 479,228 | [
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Tennis elbow. The surgical treatment of lateral epicondylitis. | Of the 1,213 clinical cases of lateral tennis elbow seen during the time period from December 19, 1971, to October 31, 1977, eighty-eight elbows in eighty-two patients had operative treatment. The lesion that was consistently identified at surgery was immature fibroblastic and vascular infiltration of the origin of the... | 479,229 | [
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Two-stage corrective surgery for congenital deformities of the spine. | Sixty patients with congenital deformities of the spine were operated upon in the past fifteen years using a two-stage procedure. In the fifty patients with scoliosis half of the deformities were due to hemivertebrae and half to unilateral bars. The average correction of the deformity was 47 per cent. Early neurologica... | 479,255 | [
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A comparison of the Freeman-Swanson (ICLH) and Walldius prostheses in total knee replacement. | Seventy-five Freeman-Swanson (ICLH) Mark I total knee replacements, all performed in one orthopaedic unit between 1972 and 1975, were independently reviewed. The fifty-eight surviving patients, with sixty-eight arthroplasties, have been interviewed and examined and the clinical records of the deceased patients inspecte... | 479,260 | [
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[Neoplastic and preneoplastic lesions in rats after oral administration of a single dose of N-nitrosomorpholine (author's transl)]. | The administration of a single oral dose of 320 mg/kg body wt. N-nitrosomorpholine (NNM) to 62 Sprague-dawley rats resulted in neoplastic and preneoplastic changes in different organs, especially in liver and kidney. After a lag period of 4 weeks, nearly all experimental animals developed preneoplastic (clear cell, aci... | 479,263 | [
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[Malignant interstitial cell tumor of testis with a marker enzyme (author's transl)]. | Metastatic interstitial cell tumor of the testis is one of the rarest human neoplasms. This is the nineteenth case to be reported. While most of these tumors are combined with hormonal dysfunction, the present tumor, apart from its uncommon hormonal profile, is remarkable because of its capacity of producing and secret... | 479,270 | [
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Correction of tetralogy of Fallot after Waterston shunt. | The authors have reviewed their experience concerning twenty-seven patients who underwent intracardiac repair of Fallot's Tetralogy after a previous Waterston shunt. They are divided into 4 groups according to the classification of Shinebourne, Anderson and Bowyer. The risk factors are analyzed in group 1 patients in w... | 479,278 | [
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Generation of asymmetry during development. Segregation of type-specific proteins in Caulobacter. | An essential event in developmental processes is the introduction of asymmetry into an otherwise undifferentiated cell population. Cell division in Caulobacter is asymmetric; the progeny cells are structurally different and follow different sequences of development, thus providing a useful model system for the study of... | 479,286 | [
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-0.1602343,
-0.051653,
0.4182829,
0.2571594,
-0.2272383,... |
Requirements for the insertion of the Sindbis envelope glycoproteins into the endoplasmic reticulum membrane. | Previous work has shown that the Sindbis structural proteins, core, the internal protein, and PE2 and E1, the integral membrane glycoproteins are synthesized as a polyprotein from a 26S mRNA; core PE2 and E1 are derived by proteolytic cleavage of a nascent chain. Newly synthesized core protein remains on the cytoplasmi... | 479,287 | [
-0.1610053,
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0.3675842,
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... |
Sperm binding and fertilization envelope formation in a cell surface complex isolated from sea urchin eggs. | An isolated surface complex consisting of the vitelline layer, plasma membrane, and attached secretory vesicles has been examined for its ability to bind sperm and to form the fertilization envelope. Isolated surface complexes (or intact eggs) fixed in glutaraldehyde and then washed in artificial sea water are capable ... | 479,292 | [
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0.4030872,
0.2710225,
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... |
Fate of plasma membrane during endocytosis. II. Evidence for recycling (shuttle) of plasma membrane constituents. | Cultured rat embryo fibroblasts were first allowed to store for 24 h fluorescein-labeled goat immunoglobulins directed against rabbit immunoglobulins (F anti-R IgG), and were subsequently exposed for 24 h to [(3)H]acetylated rabbit immunoglobulins known to bind to the cell membrane either specifically (anti-plasma memb... | 479,310 | [
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0.03284743,
0.0542473,
0.2985757,
0.1651486,
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... |
Morphological alterations in the mitochondria of Amoeba proteus induced by uncoupling agents. | Ultrastructural changes in mitochondrial morphology were observed in amoebae exposed to the uncoupling agents dinitrophernol (DNP), pentachlorophenol (PCP), and m-chlorocarbonyl cyanide phenylhydrazone (CCCP). These alterations occurred with rapidity and were present before whole-cell activity changes could be detected... | 479,326 | [
-0.2901786,
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0.3989692,
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0.2051854,
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0.1249918,
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0.116048,
0.3150472,
0.06248209,
0.003696625... |
Localization of aldosterone-producing adenoma by computed tomography. | Abdominal computed tomography (CT) was performed on nine patients with primary aldosteronism in an attempt to evaluate the utility of this noninvasive procedure in localizing aldosterone-producing adenomas. Confirmation of the diagnosis of primary aldosteronism was made by demonstrating elevated urinary aldosterone exc... | 479,353 | [
-0.194428,
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0.2892216,
0.2004958,
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0.08366999,
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Selective medium for Corynebacterium equi isolation. | The development of a selective medium for the isolation of Corynebacterium equi is described. The medium has been used to examine fecal samples from 127 horses of which 90 have been found to carry the organism. | 479,362 | [
-0.391022,
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0.04660402,
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0.1... |
Modification of hemoglobin H disease by sickle trait. | The rarity of hemoglobin (Hb) H disease in combination with sickle trait may be due in part to the absence of actual Hb H in individuals who, nonetheless, have inherited the deletion of three alpha-globin genes. We describe here a boy with persistent microcytic, hypochromic anemia despite adequate iron stores, who exhi... | 479,366 | [
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0.2816043,
0.234946,
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Activation of human factor VII in plasma and in purified systems: roles of activated factor IX, kallikrein, and activated factor XII. | Factor VII can be activated, to a molecule giving shorter clotting times with tissue factor, by incubating plasma with kaolin or by clotting plasma. The mechanisms of activation differ. With kaolin, activated Factor XII (XII(a)) was the apparent principal activator. Thus, Factor VII was not activated in Factor XII-defi... | 479,368 | [
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Staphylococci-induced human platelet injury mediated by protein A and immunoglobulin G Fc fragment receptor. | Bloodstream infections with staphylococci are accompanied by thromboembolic complications. We have studied the mechanism of the interaction of staphylococci with human blood platelets. Staphylococci that possess protein A, a bacterial receptor for the Fc fragment of immunoglobulin G (IgG), caused aggregation of human p... | 479,376 | [
-0.1569941,
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0.03437622,
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0.03830276,
0.4047748,
0.4268427,
0.1564065,
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0... |
Taste aversions to mother's milk: the age-related role of nursing in acquisition and expression of a learned association. | The development of taste aversion learning to novel cues contained in mother's milk was examined in rat pups. Pups receiving distinctive mild by experimenter-delivered oral infusions followed by toxicosis formed an aversion to the dam's diet. Robust aversions were learned as early as Day 10 and were retained for at lea... | 479,392 | [
0.1065613,
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0.1192026,
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0.1766121,
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0.1877243,
0.1175092,
0.1181073... |
Pectus excavatum deformities simulating mediastinal masses. | Three patients with various pectus excavatum deformities in whom radiographic findings suggested hilar and mediastinal masses are presented. Computed tomography of the chest yielded valuable diagnostic information and made it possible to exclude the existence of these masses. Compression deformity of the heart and grea... | 479,410 | [
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0.3870838,
0.1299186,
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0.12... |
Applications of perfluorinated compounds as contrast agents in computed tomography. | Perfluorohexylbromide, a nonionic and biologically inert radiodense compound, was evaluated as a potential contrast agent. Pulmonary and gastrointestinal administration of the neat liquid form was tested in dogs in conjunction with computed tomographic body scans. Contrast enhancement was demonstrable in one organ, the... | 479,415 | [
-0.3802879,
0.1853716,
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0.0634485,
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0.2062484,
-0.09463302,... |
Diagnosis of retro-esophageal right aortic arch by computed tomography. | A case of retro-esophageal right aortic arch was clearly demonstrated by computed tomography and confirmed by arch aortography. | 479,421 | [
-0.1053247,
0.2384872,
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0.3078704,
0.2968314,
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Biopsies of the Janeway lesion of infective endocarditis. | Janeway lesions in three patients with infective endocarditis caused by Staphylococcus aureus were biopsied. Two taken before therapy, showed evidence of suppuration and microabscesses. The other lesion which developed while the patient was on appropriate therapy, showed minimal inflammatory reaction. | 479,431 | [
-0.2275416,
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0.1044489,
0.271931,
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... |
Clinical and pathological correlation of malignant melanoma. | We have attempted to review virtually all forms of cutaneous and mucocutaneous melanomas. Superficial spreading, lentigo maligna and nodular melanomas have been more thoroughly investigated and documented in previous studies. Lentigo maligna melanoma appears to have a longer duration and better prognosis than SSM or NM... | 479,437 | [
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0.7738582,
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... |
Immune derangement in patients with malignant melanoma. | The interaction between immune system and growing tumor can be expressed differently at different stages of the disease. This presentation covers three facets of these reactions in melanoma patients. A. The Primary Tumor. Time-lapse cinematography, with an analysis of lymphocyte movement demonstrated positive and negat... | 479,438 | [
-0.1519259,
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0.2144619,
0.4607888,
0.01142227,
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Further characterization and biologic activity of ragweed antigen--induced neutrophil chemotactic activity in man. | We have previously described the appearance in serum of increased neutrophil chemotactic activity (NCA) during bronchospasm induced by inhalation of ragweed antigen in ragweed-sensitive subjects. This NCA is non-complement derived, appears within 1 min after antigen inhalation, and is not seen after methacholine-induce... | 479,476 | [
-0.2577249,
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0.1489291,
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0.3109032,
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Histopathology of experimental Schistosoma incognitum infection in mice following exposure to normal and irradiated cercariae. | The tissue reactions in mice, experimentally infected with normal and irradiated cercariae of S. incognitum were studied. The lesions observed in the skin, liver, lungs and the intestine of mice infected with normal cercariae are briefly described, and compared with those observed with cercariae irradiated at 3000 r of... | 479,540 | [
-0.3459963,
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0.3059142,
0.2744641,
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0.08750033,
-... |
Effect of rabbit strain on activity level and cytotoxicity of serum complement. III. Comparison of four tumor target cells. | Serum samples from about 10 males and 10 females from each of 15 genetically defined strains of rabbits and from one hybrid were tested as sources of complement for the microtiter lymphocytotoxicity test using tumor cells from SaI-A, 6C3HED-A, BW5147, and L-cells as target cells. The tumor cells were tested with approp... | 479,548 | [
-0.1943233,
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0.4744698,
0.4118421,
0.2964318,
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0.170... |
Immunocytochemical localization of hepatic legandin and Z protein utilizing frozen sections for light and electron microscopy. | Ligandin (glutathione-s-transferase) and Z protein are soluble hepatocellular proteins that are involved in the transfer of organic ions, including bilirubin and some hormones and carcinogens from the plasma to the liver. The intracellular distribution of ligandin and Z protein was studied by applying the peroxidase-an... | 479,557 | [
0.153904,
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0.2060747,
0.08621524,
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0.1653574,
-0.180741,
-0.0385... |
The use of lectins and cholera toxin for the detection of surface carbohydrates of cultured neurons and neuroblastoma. | Conjugates of horseradish peroxidase with the lectins ricin (d-galactose), wheat germ agglutinin (N-acetylglucosamine), phytohemagglutinin (N-acetylgalactosamine), and with cholera toxin (GM1 ganglioside) were used for a cytochemical detection of corresponding termin al carbohydrates, or glycolipids on cell surfaces of... | 479,560 | [
0.124626,
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0.2127262,
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0.475008,
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0.3074013,
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0.5154238,
0.1347091,
-0.05129557,
0.10... |
[Enzymatic chemoarchitecture of the isocortex of humans (area 10 of Brodmann)]. | The distributions of some oxidoreductases, esterases and phosphatases were investigated in the area 10 (lobus frontalis cerebri) of old human brains by means of histoenzymatic methods. It was possible to observe a different spread of enzymatic activites of hydrolases and oxidoreductases in the several layers of human f... | 479,578 | [
-0.009866671,
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0.1649015,
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0.2123334,
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0.02729269,
0.3993589,
0.3126113,
0.2966128,
0.2543243,
0.0243952... |
Antibody-mediated immunosuppression of a cytotoxic cell response not involving a simple antigen-masking mechanism. | An in vitro cytotoxic cell response against alloantigens was inhibited by antibody directed against the alloantigens and also by anti-trinitrophenyl antibody provided that the allogeneic stimulator cells were modified with trinitrophenyl. Inhibition of an anti-allogeneic cytotoxic cell response against trinitrophenyl-c... | 479,591 | [
-0.1235315,
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0.2381241,
0.09870882,
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0.05670887,
0.2793365,
0.2959841,
0.04029296,
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-0.... |
Measurement of cell-mediated inflammation in experimental murine autoimmune encephalomyelitis by radioisotopic labeling. | A radioisotopic index test was used to detect that time of onset and intensity of cell-mediated immune inflammation of experimental autoimmune encephalomyelitis (EAE) in mice. Mice were tested at various time intervals after an encephalitogenic immunization with mouse spinal cord to homogenate for delayed-type hypersen... | 479,599 | [
-0.1413148,
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0.3997287,
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0.07211243,
0.05784339,
0.3005656,
0.095086... |
Genetic control of sensitivity to Moloney leukemia virus in mice. II. Mapping of three resistant genes within the H-2 complex. | The level of viremia and the appearance of leukemias were studied after inoculation wtih Moloney leukemia virus (M-MuLV) in different H-2 congenic strains of mice. The viremia was regularly measured on individual mice with a radioimmunoassay of the major internal virion component p30. Three genes within the major histo... | 479,600 | [
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0.3150928,
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0.07638519,
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0.1310598,
0.5139798,
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... |
Antibody-dependent cellular cytotoxicity effector cell capability among normal individuals. | Nonadherent peripheral blood lymphocytes (PBL) from 110 normal individuals were evaluated for their capability to mediate antibody-dependent cellular cytotoxicity (ADCC) against rabbit antibody-sensitized chicken erythrocytes (CRBC). Titration of PBL against a constant number of chromium-51 labeled CRBC allowed for con... | 479,605 | [
-0.007567844,
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0.03470254,
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0.2132505,
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0.3061251,
0.4323557,
0.1511661,
-0.007794794... |
DNA-cytophotometry of lymph node imprints from patients with mycosis fungoides. | To obtain objective criteria for early diagnosis of lymph node involvement in patients with mycosis fundoides, Feulgen DNA-cytophotometry was carried out in lymph node imprints from patients with mycosis fungoides. The lymph nodes of 3 patients with lymph nodes, showing partial or total replacement by atypical lymphore... | 479,630 | [
-0.0166738,
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0.4154759,
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0.1171349,
0.1332268,
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0.5850732,
0.1142066,
-0.2176474,
... |
Local and systemic effects on the epidermal melanocyte population in UV-irradiated mouse skin. | Local and systemic effects of repeated UVB irradiation on the epidermal melanocytes have been studied in the C57Bl mice. A daily dose of 0.1 joule/cm2 for 10 days induced a 4-fold increase in the epidermal melanocyte population of the irradiated right ear. During the first weeks after the irradiation period, there was ... | 479,635 | [
-0.2122462,
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0.2862715,
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0.1964871,
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0.09253039,
0.2258008,
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0.2292077,
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0.1828846,
0.3676909,
0.1931992,
-0.1977357,
... |
Selection of small-colony variants of Enterobacteriaceae by in vitro exposure to aminoglycosides: pathogenicity for experimental animals. | Small-colony variants of gram-negative genera of Enterobacteriaceae were selected by in vitro exposure to gentamicin. These variants were shown to have decreased susceptibility in vitro to aminoglycosides. They were lethal for mice following intraperitoneal injection, with the LD50 (50% lethal dose) being the same as, ... | 479,639 | [
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Removal of bile acids and bilirubin by plasmaperfusion of U.S.P. charcoal-coated glass beads. | Removal of protein-bound cholephilic substances such as BA by sorbent perfusion might improve the quality of life of patients with severe inoperable cholestasis where the accumulation of BA is thought to be responsible for the often distressing pruritus. Since hemoperfusion is associated with hematological side effects... | 479,668 | [
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... |
The ultrastructure of the dorsal yolk-free cytoplasm and the immediately surrounding cytoplasm in the symmetrized egg of Xenopus laevis. | Cytoplasmic segregation and subsequent dorsad displacement of the segregated cytoplasm lead to symmetrization of the egg of Xenopus laevis. At 60 min post-fertilization (p.f.) the 'dorsal yolk-free cytoplasm' (DYFC) is located in the dorso-animal part of the egg. Its ultrastructure and that of the immediately surroundi... | 479,742 | [
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0.0... |
Cell surface antigens of human renal cancer defined by autologous typing. | Sera from 28 patients with renal cancer were tested for reactivity with surface antigens of cultured autologous renal cancer cells. Four serological assays were used to survey sera for autologous antibody. Immune adherence, protein A, and C3-mixed hemadsorption assays detected reactivity in a high percentage of patient... | 479,762 | [
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0.08956606,
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Site of binding of mouse IgG2b to the Fc receptor on mouse macrophages. | Three mouse immunoglobulins with altered heavy chains have been used to study the specificity of the mouse IgG2b Fc receptor on mouse macrophages. These immunoglobulins were synthesized by variant clones derived from the MPC 11, IgG2b-producing mouse myeloma cell line. One variant, whose Fc receptor. A second variant, ... | 479,765 | [
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0.1355257,
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0.05533404,
0.041694... |
The ionic basis of oscillatory responses of skate electroreceptors. | When physiological conditions are simulated, skate electroreceptors produce small maintained oscillatory currents. Larger damped oscillations of similar time-course are observed in voltage clamp. Subtraction of leakage in voltage clamp data shows that the oscillations involve no net outward current across the lumenal s... | 479,811 | [
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... |
Organotin-mediated exchange diffusion of anions in human red cells. | Organotin cations (R3Sn+) form electrically neutral ion pairs with monovalent anions. It is demonstrated that the tin derivatives induce exchange diffusion of chloride in red cells and resealed ghosts, without any detectable increase of membrane permeability to net movements of chloride ions. The obligatory anion excha... | 479,814 | [
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High molecular weight virus DNA in KB cells infected with ts mutants of adenovirus type 2 under permissive and non-permissive conditions. | Temperature-sensitive (ts) mutants of adenovirus type 2 (Ad2), which are deficient in virus DNA synthesis at the non-permissive temperature, have been used to investigate whether virus DNA replication is required for the occurrence of high mol. wt. Ad2 DNA (greater than 100S, 50 to 90S) in human cells productively infe... | 479,842 | [
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... |
The absence of differences in cellular immunity in elderly individuals with and without delayed local cutaneous reactions to influenza vaccine. | Two groups of elderly subjects who received bivalent influenza virus vaccine were identified. Those in Group I manifested marked local reactions, suggestive of delayed hypersensitivity reactions, whereas those in Group II, matched with Group I for vaccine preparation, had no cutaneous reactions. In vitro assays of immu... | 479,858 | [
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Role loss and working-class manic depression. | This first part of a multiphase longitudinal study looks at life events implicated in manic depression among an American working class, bipolar sample. Three turning points are identified. a) Stressful life events occurred that resulted in loss of significant social roles. b) Attempts to regain or replace the roles or ... | 479,865 | [
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0.02777833,
0.09859399,
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The interrelationship between self-image disparity and social competence, defensive style, and adjustment status. | Groups of 40 psychiatric and 40 nonpsychiatric male patients were subdivided into equal groups of high and low social competence. Each patient completed a task battery which included three measures of self-image disparity and the Byrne repression-sensitization scale. High competence patients of both types were found to... | 479,868 | [
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A highly sensitive and precise radioenzymatic assay for plasma epinephrine and norepinephrine. | A modification of the procedures for simultaneous radiometric determinations of plasma epinephrine (E) and norepinephrine (NE) was developed. High performance liquid chromatography (HPLC) is excellently suited to separate the radioactive products of the enzymatic methylation of catecholamines. The time-saving procedure... | 479,874 | [
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An in situ study of the hypothalamo-neurohypophysial complex of the freshwater teleost Ompok bimaculatus (Bloch) with a note on the tetrapodan features of its vascularization. | In Ompok bimaculatus the neurosecretory axons of both the pars magnocellularis and pars parvocellularis component of the nucleus preopticus contribute to the formation of the left and right main tracts. At rostral levels, one third of the tracts are loosely built forming a king of curtain, while they become more compac... | 479,875 | [
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Influence of fluoride on the uptake of 51Cr-chromate by human erythrocytes. | Uptake of 51Cr-chromate by freshly collected human erythrocytes was inhibited by 90 mM sodium fluoride only in cells preincubated with fluoride. In vitro storage also increased the sensitivity of the cells: 90 mM NaF clearly inhibited the uptake of chromate in cells stored in vitro for 5 weeks. Gel chromatography revea... | 479,876 | [
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Involvement of peripheral vasomotor fibres in carpal tunnel syndrome. | It is often assumed that large diameter nerve fibres are affected selectively in patients with compressive peripheral nerve lesions. However, in five of 13 patients with the carpal tunnel syndrome, plethysmography revealed that the normal digital vasoconstrictor response to inspiration was abolished in the index finger... | 479,905 | [
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0.2497806,
... |
Cluster headache: trial of a combined histamine H1 and H2 antagonist treatment. | Fifteen patients with symptomatic cluster headache participated in a double-blind crossover trial of a combined histamine H1 and H2 antagonist treatment. The trial lasted six weeks. There was no significant improvement on active treatment as regards mean number of headache attacks per week, intensity, or duration of at... | 479,908 | [
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Superficial temporal-middle cerebral artery bypass. A detailed analysis of multiple pre- and postoperative angiograms in 40 consecutive patients. | Pre- and postoperative angiograms on 40 patients undergoing superficial temporal-middle cerebral artery (STA-MCA) bypass surgery have been examined in detail. Multiple postoperative angiograms have been obtained to evaluate the change in both the bypass circuit and the intracranial circulation over time. A reproducible... | 479,932 | [
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Xanthogranuloma of the third ventricle. Case report. | The case history of a patient with a xanthogranuloma of the third ventricle is presented. This type of lesion formed by desquamation of epithelium is usually noted as an incidental autopsy finding in the choroid plexus of the lateral ventricles. Total removal via a transcortical transventricular route led to complete r... | 479,942 | [
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0.3137091,
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Long term pancreatic response to feeding heat damaged casein in rats. | Rats were fed a heat damaged casein (autoclaved 24 hours, 121 degrees, 2 atm) diet to determine the effect of poorly digested protein on pancreatic enzyme levels and response to a meal. After 10 days of feeding, the pancreas showed no signs of atrophy, however, chymotrypsin and amylase activities were lower in proporti... | 479,954 | [
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-... |
Autoantibodies to Tamm-Horsfall protein associated with urinary tract infections in girls. | Girls with various forms of urinary tract infections and a reference material were analyzed for autoantibodies in serum to the Tamm-Horsfall glycoprotein. Such antibodies could be detected in all sera analyzed. In the control subjects cord blood contained very low IgA and IgM anti-TH, which increased significantly up t... | 480,012 | [
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Refractory hypoxemia associated with neonatal pulmonary disease: the use and limitations of tolazoline. | Thirty-nine critically ill infants with pulmonary disease received tolazoline because of severe hypoxemia refractory to administration of 100% O2 and mechanical ventilation. Twenty-seven (69%) of the infants responded with an increase in PaO2 greater than or equal to 20 torr in the first umbilical arterial gas after co... | 480,041 | [
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0.0564649,
0.07756439,... |
Aspirin dosage for infants and children. | The labeled dosage schedule that has long been on pediatric aspirin preparations is at variance with the recommendation in authoritative medical references, studies demonstrating antipyretic effectiveness in children, and the prescribing habits of pediatricians as revealed by a poll conducted by the authors. Aspirin ph... | 480,047 | [
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0.4602382,
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... |
The effects of miracidal aging and dilution of snail-conditioned water on responses of miracidia of Megalodiscus temperatus. | Miracidia of Megalodiscus temperatus from newly hatched until 10 hr old were tested for their ability to react to Helisoma trivolvis snail-conditioned water (SCW) by contact with return (CR) to agar blocks and by percentage of miracidia reacting to a point inoculation of SCW as determined by a photographic time exposur... | 480,075 | [
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0.1565705,
... |
Diclidophora embiotocae sp. n. (Monogenea, Diclidophoridae), a parasite of embiotocid fishes of Oregon. | Diclidophora embiotocae sp. n. is described from adult specimens obtained from the gills of three species of embiotocid fishes from the central coast of Oregon. It differs from all other members of the genus in hosts, geographic location, and in possessing pre- and para-ovarian, as well as post-ovarian testes. Diagnosi... | 480,078 | [
-0.04632699,
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0.1186922,
-0.05... |
Bronchogenic cyst. | Two recent patients with bronchogenic cysts, presenting in an atypical manner, stimulated our review of this subject. Twenty patients with bronchogenic cysts have been treated at the Boston Floating Hospital over the past 20 yr. Of these patients, 19 out of 20 were symptomatic, the most common symptom being fever (6 ou... | 480,084 | [
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0.1154945,
0.01341172,
-0.300101... |
Examination of blood clobazam levels and several pupillary measures in humans. | The State-Trait Anxiety Inventory was administered to 15 subjects before initiation of the experiment. Three subgroups of five subjects were defined by computing the unweighted sum of the state and trait anxiety scores. A 40-mg dose of clobazam, a 1.5-benzodiazepine, was administered to each subject and repeated with t... | 480,152 | [
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0.4477775,
0.03231007,
0.1280869,
0.03131249,
... |
High-pressure liquid chromatographic analysis of antipyrine in small plasma samples. | A high-pressure liquid chromatographic (HPLC) method was developed for the assay of antipyrine in small (0.1-ml) plasma samples using aminopyrine as the internal standard and a reversed-phase microparticulate column. The assay sensitivity (1 microgram/ml) permits development of a plasma level--time curve using a single... | 480,161 | [
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0.236512,
0.08569795,
0.1096491,
0.06483429,
-0.... |
Effect of enzyme-inducing and enzyme-inhibiting agents on drug absorption. II. Influence in proadifen on 3-O-methylglucose transport in rats. | Studies utilizing the in vitro everted rat jejunum were performed to investigate the effects of proadifen pretreatment and fasting on active and passive intestinal transfer of 3-O-methylglucose. Animals were pretreated 24 hr prior to the experiments with 100 mg of proadifen/kg ip. With mucosal concentrations of 0.1 mM ... | 480,172 | [
-0.1180122,
-0.2061672,
-0.4153754,
-0.2383401,
0.009953296,
-0.2515098,
0.2028781,
-0.02004558,
0.01863663,
-0.4058989,
0.2928953,
0.1563436,
0.1989819,
0.1464389,
-0.4881366,
0.0999314,
-0.6132856,
0.1139266,
-0.2221349,
0.3739696,
0.151238,
0.1649131,
-0.1926443,
0.2... |
Simple field test for marijuana. | A simple, rapid, sensitive, and specific field test for marijuana and its products is described. The test employs an extracting-eluting ssolvent and an inert adsorbent microcolumn coated with Fast Blue B salt as the reagent. One milligram or less of the suspect material can be tested within 1 min. Of greater than nonma... | 480,177 | [
-0.02146325,
0.2900282,
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0.1279221,
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0.4330689,
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0.04675086,
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0.08271164,
0.2605446,
0.1388943,
0.1704814,
0.40084,
-0.2615403,
0.00364311,
-0... |
Mechanism of frequency-dependent broadening of molluscan neurone soma spikes. | 1. Action potentials recorded from isolated dorid neurone somata increase in duration, i.e. broaden, during low frequency repetitive firing. Spike broadening is substantially reduced by external Co ions and implicates an inward Ca current. 2. During repetitive voltage clamp steps at frequencies slower than 1 Hz, in 100... | 480,247 | [
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0.09589921,
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0.06192735,
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0.08542311,
0.02405958,
0.7183337,
0.2789013,
0.31... |
Effects of model warmth on acquisition and performance of modeled behavior in chronic psychotics. | Hypotheses derived from an earlier study were tested in experimental dyads with 32 adult chronic psychotic state hospital residents of both sexes. Patients either interacted with an adult model who was noncontingently warm and rewarding, or were not exposed initially to a model. In a second phase, the model displayed t... | 480,266 | [
-0.3510557,
0.06190154,
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0.0007439867,
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-0.4665486,
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-0.2610623,
0.01941771,
0.2050064,
0.08093888,
0.0623... |
Discrimination learning in preschool children as a function of the stimulus and relevant dimension. | The purpose of the present study was to determine discrimination learning rates as a function of the nature of the stimulus and the relevant dimension. Ss were 160 preschool boys and girls. The design consisted of two stimuli (faces and cups), two constant dimensions (size and form), and two relevant dimensions (form a... | 480,271 | [
-0.02422436,
0.2392561,
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0.2300857,
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0.1344826,
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0.04652553,
0.1119106,
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0.1067343,
0.3832356,
-0.03850471,
-0.192... |
Attempted cross-transmission of coccidia between sheep and goats and description of Eimeria ovinoidalis sp. n. | Attempted infection of 2 young lambs with oocysts of Eimeria christenseni from a goat was unsuccessful. Negative results were obtained also when young kids were fed oocysts of Eimeria ninakohlyakimovae from sheep. There was no difficulty in infecting lambs with the sheep coccidium resembling E. ninakohlyakimovae nor go... | 480,272 | [
-0.1686622,
0.1216171,
0.167945,
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0.2391119,
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0.07304242,
0.1605721,
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0.2071206,
0.149917,
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0.3243681,
0.04776162,
-0.2010639,
0.2734998,
0.3141314,
-0.3391819,
0.233... |
An experimental investigation of the modifiability of the temporal structure of spontaneous speech. | This study attempted to test the hypothesis that the temporal structure of spontaneous speech is modifiable by reinforcing and punishing pauses, of a certain duration, in an operant conditioning situation. Pause rate was significantly affected by these contingencies: moreover, rate of change was rapid, indicating a "pr... | 480,274 | [
0.01157909,
0.1225207,
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0.3386792,
0.4707792,
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0.03684326,
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0.09710145,
0.1276344,
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0.1589917,
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0.1716846,
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0.05856225,
... |
Urine microscopy and infection in general practice. | To test the value of urine microscopy 100 consecutive specimens were examined in the surgery and the results correlated with the subsequent laboratory culture reports.An assessment of the degree of pyuria was made by low power microscopy of a thick drop of fresh urine. A second specimen was examined under high power fo... | 480,294 | [
0.004140918,
0.2054296,
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0.0251906,
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0.1126782,
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0.2022047,
0.2877396,
0.01790561,
0.08525872,
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0.08594511,
0.2272535,
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0.1509636,
0.3630168,
-0.0172443,
0.1520457,
0.0... |
Synthesis of steroids by echidna (Tachyglossus aculeatus) testis and the effects of gonadotrophin administration. | After administration of hCG and PMSG to male echidnas (in non-breeding state) the testis to body weight ratio increased 3-fold and the diameter of the seminiferous tubules doubled, but spermatogenesis was not induced. The major conversion product of testicular homogenate with [4-14C]progesterone as substrate was 17 alp... | 480,305 | [
-0.09021231,
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0.05905376,
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0.05586952,
0.01888878,
0.302113,
0.4108884,
0.1444654,
-0.1303087,
... |
Time requirement for capacitation of boar spermatozoa assessed by their ability to penetrate the zona-free hamster egg. | Boar spermatozoa were preincubated for various times in the isolated uterus and oviduct from a maturing gilt and used to inseminate zona-free hamster eggs. The proportions of eggs penetrated and activated were increased, and the interval between insemination and sperm penetration was shortened when the spermatozoa were... | 480,306 | [
0.1449739,
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0.2146431,
0.3069785,
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0.2264851,
0.2510393,
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0.206098,
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0.04753552,
0.02235759,
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-0.5718259,
0.2053386,
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-0.2420843,
0.5659301,
0.2044445,
0.07833051,
... |
Electrical properties of the cellular transepithelial pathway in Necturus gallbladder: III. Ionic permeability of the basolateral cell membrane. | The ionic permeability of the basolateral membrane of Necturus gallbladder epithelium was studied with intracellular microelectrode techniques. After removal of most of the subepithelial tissue (to reduce unstirred layer thickness), impalements were performed from the serosal side, and ionic substitutions were made in ... | 480,334 | [
-0.110363,
-0.0576113,
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0.03060692,
0.1243269,
0.1194308,
0.04479358,
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0.08715525,
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-0.5562655,
-0.003996731,
-0.2996787,
0.3167886,
0.497472,
-0.07991064,
0.288701... |
Reversible electrical breakdown of lipid bilayer membranes: a charge-pulse relaxation study. | Charge-pulse experiments were performed with lipid bilayer membranes from oxidized cholesterol/n-decane at relatively high voltages (several hundred mV). The membranes show an irreversible mechanical rupture if the membrane is charged to voltages on the order of 300 mV. In the case of the mechanical rupture, the voltag... | 480,336 | [
0.03713745,
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0.1180818,
0.3244203,
0.2738187,
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0.06045542,
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-0.05418509,
0.4371974,
0.3485186,
0.0140149,
0.0001127... |
Intracellular ionic activities and transmembrane electrochemical potential differences in gallbladder epithelium. | Intracellular ion activities in Necturus gallbladder epithelium were measured with liquid ion-exchanger microelectrodes. Mean values for K, Cl and Na activities were 87, 35 and 22 mM, respectively. The intracellular activities of both K and Cl are above their respective equilibrium values, whereas the Na activity is fa... | 480,341 | [
-0.2364167,
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0.03131577,
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0.1022402,
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0.1138126,
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-0.02207203,
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0.6292443,
-0.1619543,
0.2313... |
A case of ovarian pregnancy. | Ovarian pregnancy is an uncommon event, the cause of which is unknown. The use of the intrauterine device (IUD) has increased the incidence of ovarian pregnancy. This is due to the decreasing contraceptive effect of the IUD on the fallopian tube and the ovary. This case satisfies the four criteria of Spiegelberg. It al... | 480,394 | [
-0.01801554,
0.06574951,
0.11295,
0.1632174,
0.1153579,
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0.2775065,
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0.02645214,
0.3052964,
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0.2082048,
0.08392975,
-0.3709309,
0.06701218,
0.2301491,
-0.1470625,
... |
Reproduction study of carteolol hydrochloride in mice. Part 2. Peri -and postnatal toxicity. | Carteolol was orally administered to mice once a day at doses of 3, 30 and 150 mg/kg/day during the perinatal and lactation periods and evaluated on its adverse effects on pregnant animals and their offspring. No appreciably abnormal findings related to the drug administration were revealed. Therefore, it was concluded... | 480,406 | [
-0.1044815,
0.004930441,
-0.2971672,
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0.1490625,
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-0.1867526,
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0.2261599,
-0.2583948,
-0.2264045,
0.2370979,
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0.1971746,
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0.3547344,
0.2140134,
0.1540288,
-0.1131425,
0.5352154,
-0.02301158,
... |
Generation of defective interfering particles of Semliki Forest virus in a clone of Aedes albopictus (mosquito) cells. | Serial undiluted passage of Semliki Forest virus in a clone of Aedes albopictus cells resulted in a marked decrease in infectious virus yields due to the generation and accumulation of defective interfering particles. Virus from the third passage had a high particle/infectivity ratio and interfered specifically with ho... | 480,458 | [
-0.03807657,
0.26869,
0.1462997,
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0.4446732,
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0.1180158,
0.3752327,
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0.2021237,
-0.3868765,
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0.169543,
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0.1531318,
0.02134915,
-0.1475246,
0.2311584,
-0.1234355,
-0.03242806,
0.0... |
RNA-directed DNA synthesis in Moloney murine leukemia virus: interaction between the primer tRNA and the genome RNA. | Initiation of RNA-directed DNA synthesis in virions of Moloney murine leukemia virus requires a cellular tRNAPro as primer. The site(s) on the Moloney murine leukemia virus genome RNA at which functional primer molecules are bound and at which purified tRNAPro hybridizes has been located near (within 20%) the 5' end of... | 480,476 | [
-0.3762536,
-0.1021003,
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0.2858319,
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0.1818954,
0.1528021,
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0.07264446,
0.06424955,
0.01302912,
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0.0004712194,
-0.0736445,
0.003344096,
-0.3311867,
0.3109146,
0.5204223,
-0.0900538,
-0.2409... |
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