title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Separation of normal human bone marrow cells by counterflow centrifugal elutriation. I. Morphological analysis and subfractionation of neutrophilic granulocytes. | We have used counterflow centrifugal elutriation to separate the nucleated cells of normal human bone marrow into their major morphologically identifiable cellular components. Human bone marrow cells were separated simultaneously into the major cell types--lymphocytes, monocytes, granulocytes, and erythroid precursors.... | 510,435 | [
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Biotransformation of polyprenols by the larvae of Pieris rapae crucivora. | The biotransformation of cleomeprenols-1-3H by the larvae of Pieris rapae crucivora Boisduval has been investigated. It was found that cleomeprenols fed to the larvae are transformed into long chain fatty acid esters that are excreted in the feces. | 510,462 | [
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The metabolism of the soil fumigant 1,2-dibromo-3-chloropropane in the rat. | The soil fumigant 1,2-dibromo-3-chloropropane (I) undergoes hydrolysis in the rat to a series of epoxide metabolites. Alkylation of glutathione by these epoxides produces 2 urinary metabolites identified as the mercapturic acids VI (R=COCH3) and VII (R-COCH3). Hydrolysis of the epoxides produces the male antifertility ... | 510,467 | [
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Karyology of the primitive salamanders, family Hynobiidae. | Karyotypes have been studied in 3 species of Hynobius and in 1 species each of the remaining genera of Hynobiids (Ranodon, Batrachuperus, Salamandrella and Onychodactylus). All species have large diploid numbers, between 56 and 66, and asymmetrical and bimodal karyotypes. DNA contents (2C) were found to vary between 33... | 510,468 | [
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Cytogenetics of South American akodont rodents (Cricetidae). V. Segregation of chromosome No. 1 polymorphism in Akodon molinae. | Akodon molinae is polymorphic with 2n=42, 43, 44, where the metacentric autosome No. 1 is homologous to 2 acrocentrics 1a and 1b. Matings between 2n=43 heterozygotes 1/1a, 1b gave a surplus of 1/1 offspring, a moderate reduction of heterozygous and a strong reduction of homozygous 1a, 1b/1a, 1b offspring. The latter ty... | 510,469 | [
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Lemming cycles in captivity. | 2 freely growing confined populations of Norwegian lemmings displayed population peaks and declines which were similar to natural populations. In most other studies of confined populations of rodents, the number of animals stabilized and maintained fairly constant numbers. Juvenile mortality and reduced pregnancy rate ... | 510,481 | [
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The excretion of urea by the larvae of Spodoptera mauritia Boisd. (Noctuidae: Lepidoptera) during development. | The concentration of urea in the excreta of the 6th instar larvae of Spodoptera mauritia varies from 4.017 +/- 0.541 to 31.052 +/- 1.193 mumoles/g dry excreta (mean +/- SE). The observation confirms that urea excreted is of metabolic origin. | 510,484 | [
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Doxorubicin 14-ethers. | The synthesis and the antitumor activities of a group of doxorubicin (adriamycin) 14-ethers are reported. The new compounds were found to have an activity similar to that of daunorubicin, at somewhat higher doses, but inferior to that of doxorubicin. | 510,533 | [
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[Changes in brain temperature in dogs while running]. | Brain temperatures in different sites, rectal, aortal temperatures, and ventilation rate were measured in 3 dogs during treadmill running at 90 m/min, ambient temperature being 19-24 degrees C. External sites of the brain had a higher temperature than internal ones. Approximately the same temperature gradient was obser... | 510,627 | [
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[Effect of urea on the mechanism of percutaneous permeation]. | The influence of urea on the percutaneous permeation under different conditions of application and on the epidermal effectiveness of 5-fluorouracil (FU) as an example for water-soluble agents is reported. The proceedings of permeation of FU are accelerated by admixture of, or pretreatment with, urea and by increasing t... | 510,648 | [
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Genetic selection for diabetogenic traits in Yucatan miniature swine. | Yucatan miniature pigs have been selectively bred for reduced and increased glucose clearance during an intravenous glucose tolerance test. Pigs with low glucose clearance rates (low K) have been selected through the F-5 generation. They have a significantly reduced rate of glucose clearance and a blunted peripheral IR... | 510,807 | [
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Long-term experiment of maximal non-carcinogenic dose of dimethylnitrosamine for carcinogenesis in rats. | Studies were made on the maximal non-carcinogenic dose of dimethylnitrosamine (DMN) in rats. Groups of Wistar strain rats of both sexes, 6 weeks old, were given standard diet without DMN (group 1), or containing 0.1 ppm DMN (group 2), 1.0 ppm DMN (group 3), or 10 ppm DMN (group 4) for 96 weeks and then sacrificed for h... | 510,853 | [
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Zollinger-Ellison syndrome presenting as esophageal stricture. | A case of Zollinger-Ellison syndrome in an elderly man who presented with dysphagia and subsequently developed esophageal stricture is described. This is an infrequent concomitant of the Zollinger-Ellison syndrome, especially as a presenting complaint. The literature on esophageal involvement in the Zollinger-Ellison s... | 510,871 | [
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[Surgical treatment of tubal sterility macrosurgery versus microsurgery? (author's transl)]. | Results of surgical treatment of tubal sterility obtained via "microsurgery" are compared with those of "microscopic microsurgery", as far as it is possible at this stage. Preliminary resumé: Microscopic technique obviously produces better results in reanastomoses after sterilisation, whereas in the case of salpingosto... | 510,894 | [
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Performance on three cognitive tasks by patients with dementia, depression or Korsakov's syndrome. | Perception, attention and recall were measured in geriatric subjects and patients suffering from dementia, Korsakov's psychosis or depression. Dementia patients were unable to perceive, attend and recall; depressed patients were unable to attend; and patients with Korsakov's psychosis were unable to attend and recall. ... | 510,928 | [
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Linear skeletal growth in male and female turkeys. | Growth in the maximum length of the skull, humerus, ulna + radius, carpometacarpus + phalanges, pelvis, femur, tibiotarsus and tarsometatarsus + phalanges was measured by dissection of male and female white turkeys taken at 14 day intervals from hatching to 20 weeks. In all skeletal units except carpometacarpus + phala... | 510,955 | [
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Albumin-bound fatty acids, platelets and endothelial cells in thrombogenesis. | Changes in the types and concentrations of albumin-bound fatty acids in plasma have been related to subsequent changes in platelet and endothelial cell function both in vitro and in vivo. Fatty acids in the linoleate and linolenate sequences with the potential to act as prostaglandin and thromboxane precursors, seem to... | 511,009 | [
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The role of endothelial cells and subendothelial components in the initiation of blood coagulation. | The effect of collagen on isolated platelets, platelet-rich plasma and whole blood has been studied. Collagen failed to generate factor XIa-like activity in mixtures of isolated platelets, collagen and Ca++. Moreover, collagen added to whole blood or platelet-rich plasma containing 125I-factor IX and Ca++, also failed ... | 511,012 | [
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The vascular wall and fibrinolysis. | A survey is given of recent data pertaining to the presence of components of the fibrinolytic system in the vascular wall. Activators and inhibitors of fibrinolysis were shown to be present in the vessel wall, while activators were mainly found in the endothelial cells, and inhibitors in the media. Activators will be r... | 511,013 | [
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Alcohol abuse programs in the military. | Human resource programs generally have a low priority in the military, but in 1971 the armed forces began a major program to control alcohol abuse. In 1980 the program will spend $50 million. This article discusses the program's successes and problems and the part social workers play in it. | 511,028 | [
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Ecology of sympatric gibbons. | Ecological compatibility of sympatric gibbons is achieved by a difference in diet resulting from the effect of differing body sizes on the efficiency of harvesting different foods. In addition, differences in feeding apparatus and body size between the large and small species maximise the rate at which each can eat its... | 511,046 | [
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Assay of major and minor constituents of opium samples and studies of their origin. | Samples of opium from different countries as well as from various regions of India were studied for their morphine and codeine content by gas-liquid chromatography (GLC) as their silyl ethers in a single step. Non-phenolic alkaloids (thebaine, papaverine and narcotine) were extracted with dichloromethane for GLC after ... | 511,051 | [
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[Osteonecrosis morbus Friedrich]. | This report presents in detail the aseptic bone necrosis of the sternal end of the clavicle, the so-called M. Friedrich. When pain persists this relatively rare illness can be operated successfully. | 511,061 | [
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[Screening for elevated creatine kinase activities for the early diagnosis of Duchenne muscular dystrophy]. | A screening test for the determination of creatine kinase in a dry spot of the whole blood is used for the early identification of boys with Duchenne muscular dystrophy and girls with carrier properties of this hereditary disease. In the absence of an effective medical therapy, such screening leads to genetic counselli... | 511,067 | [
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[Profiles of polycyclic aromatic hydrocarbon metabolites after treatment with various inducers of microsomal rat liver monoxygenases (author's transl)]. | The microsomal oxidation of 12 frequently occurring environmental polycyclic aromatic hydrocarbons after incubation with rat-liver microsomes has been studied and their metabolites characterized by means of gas-liquid chromatography/mass spectrometry. The method enables the detection and characterisation of phenols, di... | 511,090 | [
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Self-association of band-protein from human erythrocyte membranes in aqueous solutions. | Band 3, the main integral protein of the human erythrocyte membrane, was solubilized and purified in high concentrations of acetic acid. After removal of the organic solvent by dialysis, the self-association of the protein in aqueous solutions was studied by analytical ultracentrifugation. Sedimentation velocity and se... | 511,096 | [
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The genetic hypothesis for susceptibility to lepromatous leprosy. | Evidence for genetic influence of the host response to infection with Mycobacterium leprae is reviewed. A complex segregation analysis is performed on data for 91 families from Mactan, Philippines, in each of which at least one offspring developed lepromatous leprosy. The data are not found to be inconsistent with an a... | 511,131 | [
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Structural differences in reciprocal translocations. Potential for a model of risk in Rcp. | Interchange segment sizes and the sizes of chromosome imbalance arising from the different modes of meiotic segregation were measured in a selected sample of 20 reciprocal translocations (Rep). The Rep were selected by two modes of ascertainment: (I) neonates with an unbalanced form of the translocation, and (II) coupl... | 511,145 | [
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0.3474413,
-0.3406906,
0.2593248,
0.33111,
-0.002382024,
... |
Trisomy 9p resulting from de novo 9/15 translocation and a 9p isochromosome. | Trisomy 9p with de novo 9/15 translocation and 9p isochromosome was observed in a mentally defective boy with typical clinical features for this syndrome. This chromosomal aberration is probably caused by the pericentric inversion of chromosome 9 of the patient's father. | 511,173 | [
-0.4235969,
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Expression of esterase D and other gene markers in trisomy 13. | A gene dosage effect was observed for esterase D in a patient with trisomy 13. Isoelectric focusing of hemoglobin from the same patient showed three unidentified bands. A gene dosage effect for several other enzymes was not observed in two other patients with trisomy 13. | 511,174 | [
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-... |
HLA-GLO linkage analysis in 57 informative families. | The HLA-GLO linkage relationship was investigated among 37 single backcross families with 97 children and 20 double intercross families with 51 children. For the total number of families the value Zmas = 14.600 for theta = 0.060 was found. A total of 11 cross-overs between HLA and GLO were found leading to a recombinat... | 511,191 | [
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Kinetics of humoral responsiveness and antigenic distribution in operated rats. | Wistar R/A rats were injected intravenously with 10(9) sheep red blood cells (SRBC) prior to, during or after a standard laparotomy. Stimulation of anti-SRBC antibody synthesis was already observed when the antigen was given 4 h prior to surgery and was maximal if SRBC were administered at the time of operation. The en... | 511,217 | [
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0.0984... |
In vitro transfer of cellular immunity in experimental allergic orchitis by means of immune RNA. | Ribonucleic acid (RNA) extracts were obtained from lymph nodes of guinea-pigs that had previously been immunized with a purified testicular antigen emulsified in Freund's complete adjuvant. The RNA extracts were incubated with normal guinea-pig peritoneal exudate cells (NGP-PEC). After treatment, the NGP-PEC cells show... | 511,220 | [
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Permeability factor contaminating hyaluronidase preparations. | Both crude and highly purified testicular hyaluronidase preparations have been shown to contain a component which increases the permeability of the microcirculation in rat skin. This permeability activity had an isoelectric point of 7.4 while hyaluronidase was 9.4. It also could be separated from hyaluronidase by acryl... | 511,298 | [
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0... |
Infectious episodes in severely granulocytopenic patients. | In a prospective study, 40 episodes of granulocytopenia (granulocytes less than 500/mm3) in 34 patients were analyzed. During 52.5% of these episodes there was proven infection; these infections were present for only 24.4% of the 1,435 granulocytopenic days. The risk of infection and mortality were closely linked with ... | 511,334 | [
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0.0933428,
0.15928... |
25-hydroxycholecalciferol in the treatment of renal osteodystrophy in haemodialysed patients. | The effects of 25-OHD3 on renal osteodystrophy have been studied in 6 patients on maintenance haemodialysis. Administration of 25-OHD3, 50 microgram/day, did not improve biochemical data and intestinal absorption of calcium. With a dose of 100 microgram/day in all patients an increase in blood calcium levels eventually... | 511,368 | [
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An iterative algorithm for analysis of variance. | In this paper, an iterative algorithm is proposed for computing estimates of parameters and sums of squares in non-orthogonal multivariate analysis of variance, without inverting any matrix. It is useful in the case of a large design matrix for it saves memory and computation time. It was first proposed by Stevens (194... | 511,387 | [
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Changes of electrolyte excretion, renin activity, angiotensin-II and aldosterone concentrations during administration of 3-amino-1-(3,4-dichloro-a-methyl-benzyl)-2-pyrazolin-5-one (Bay g 2821). | After the administration of 40 mg Bay g 2821, a new potent diuretic substance, a significant increase of sodium and water diuresis occurred. There was only a short rise in potassium excretion. In contrast to the sodium and water diuresis no significant increase of renin-activity, angiotensin-II or aldosterone concentra... | 511,420 | [
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Patterns and intensity of autofluorescence and its relation to melanin in human epidermis and hair. | The skin of 41 patients including 16 blacks, 15 Caucasians, and 10 Hispanics, was observed using a fluorescent microscope. Three patterns of autofluorescence were observed: intercellular, cytoplasmic, and a combination of intercellular and cytoplasmic. The hair of 75 subjects, including 18 Negroes and 55 Caucasians, wa... | 511,435 | [
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Substance P-like immunoreactive nerves in mammalian lung. | Substance P-like immunoreactivity was located in nerves in the lungs of guinea pig, rat, mouse and neonatal pigs. These nerves were regularly observed in association with both airways and blood vessels in all region of the lung. They appeared to be more numerous in the guinea pig than in the other mammals studied and d... | 511,607 | [
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0.09957451,
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Recovery characteristics of the acoustic reflex. | Acoustic-reflex recovery time was measured as a function of activator intensity level and duration for broad-band noise and a 500-Hz tone in 10 normal-hearing subjects. The activating signals were presented at 5 and 10 dB above individual acoustic reflex thresholds for durations ranging from 0.25 to 100 sec. Reflex-rec... | 511,646 | [
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... |
Influence of ear canal air pressure on acoustic reflex threshold. | This study was undertaken to investigate the effects of ear canal air pressure variation on the threshold of acoustic reflex. The acoustic reflex threshold was obtained to 500 and 1000 Hz activating signals as pressure was varied between +/- 200 mm H2O. The results demonstrated a reduction in sensitivity of the acousti... | 511,654 | [
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0.2679... |
Influence of skin temperature on sweating and aerobic performance during severe work. | Two male subjects were measured over a range of work intensities at dry-bulb temperature (Tdb) = 21 degrees C (relative humidity, rh less than 50%) and at approximately 65 and 85% VO2max for 1 h at Tdb at 5,10,15,21, and 25 degrees C with high convective airflow (2.5-5 m/s). The results showed that mean skin temperatur... | 511,684 | [
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Effect of anemia on oxygen transport in hemorrhagic shock. | Effect of anemia on tolerance of hemorrhagic shock in rats was studied to examine opposing effects of altered oxygen capacity and viscosity on oxygen delivery at reduced blood flow. Hematocrit was first reduced by exchange transfusion. Hypotension (BP = 30 Torr) was induced and maintained at this level by controlled he... | 511,697 | [
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Protein metabolism in lung. II. Influence of amino acids and glucose on protein degradation. | We used the isolated perfused lung to study protein degradation. Proteins were labeled in vivo during 10 min (fast) or 5 h (slow). The absence of exogenous amino acids lowered the rate of proteolysis of fast but not of slowly turning over proteins. Addition of normal rat plasma levels of amino acids, after 45 min of pe... | 511,706 | [
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Polioencephalomalacia in goats. | Of six goats with polioencephalomalacia, three responded to thiamin therapy, whereas three died 2 to 7 days after onset of signs. The goats were 2 months to 2 1/2 years old. They were affected during the winter or early spring, and concentrate feeding was a prominent part of the history. Transketolase activity values w... | 511,735 | [
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Herbicidins F and G, two new nucleoside antibiotics. | A mutant of Streptomyces saganonensis No. 4075, obtained with N-methyl-N'-nitro-N-nitrosoguanidine treatment, produced herbicidins F and G without herbicidins A and B. Isolation of the antibiotics was performed by adsorption on resinous adsorbent followed by elution with aqueous MeOH. Herbicidin F was obtained as color... | 511,776 | [
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Conglobatin, a novel macrolide dilactone from Streptomyces conglobatus ATCC 31005. | Fermentation of deposited cultures of Streptomyces conglobatus, known to produce the polyether antibiotic, ionomycin has resulted in the isolation and characterization of a second metabolite, conglobatin (C28H38N2O6). X-Ray analysis revealed a dimeric macrolide dilactone structure for conglobatin, similar to the struct... | 511,778 | [
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Occurrence of hematoside with two moles of N-acetyl-neuraminic acid in a certain breed of Persian cat. | The glycolipids of erythrocytes from individual cats were examined. The main glycolipid of cat erythrocytes was generally NeuGc-NeuGc-Gal-Glc-ceramide (NeuGc-GD3), but among 41 cats of 5 breeds and 2 mongrels examined, 2 Persian cats were found to have NeuAc-NeuAc-Gal-Glc-ceramide (NeuAc-GD3). This is the first report ... | 511,844 | [
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Studies on the glycosphingolipids of the starfish, Asterina pectinifera. III. Isolation and structural studies of two novel gangliosides containing internal sialic acid residues. | Two gangliosides, provisionally named Gangliosides 1 and 2 in previous studies, were isolated from starfish, Asterina pectinifera by silicic acid, DEAE-Sephadex, and Iatrobeads column chromatography procedures, and preparative thin-layer chromatography, and their structures were established. On the basis of the results... | 511,847 | [
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Contact pressure dependence of wear rates of ultra high molecular weight polyethylene. | Wear rates of orthopaedic polyethylene in 37 degrees C water are not very contact stress dependent below 1000 psi (6.9 MPa) but above that level they accelerate substantially. The pressure dependence overall follows an exponential function. Creep in the contact pressure range of 3--17 MPa and above is a much larger fac... | 511,863 | [
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Giant ureteral calculi. | Giant ureteral calculi are defined as weighing at least 50 g or measuring more than 5 cm in greatest diameter. Two patients with this rare entity are described. | 511,906 | [
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Surgical management of carotid artery aneurysm with ball valve thrombus. | Operative repair of extracranial carotid artery aneurysms has been infrequently reported. A unique case is presented in which an aneurysm of the cervical internal carotid artery contained a ball valve thrombus. The patient experienced transient ischemic attacks whenever a position was assumed which permitted occlusion ... | 511,910 | [
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Atrial septal defect: repair in patients over thirty-five years of age. | Fifty-eight patients over age 35 underwent repair of atrial septal defect. The operative mortality was zero for the seven N.Y.H.A. class I and 26 N.Y.H.A. class II patients. One of 16 class III patients and two of nine class IV patients died; consequently, overall hospital mortality was five percent. The operative mort... | 511,926 | [
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Regional differentiation of the sperm surface as studied with 125I-diiodofluorescein isothiocyanate, an impermeant reagent that allows isolation of the labeled components. | The regional differentiation of the sperm surface has been studied with the aid of a novel covalent labeling technique that permits concurrent cytological, biochemical, and immunological analyses. For these studies isothiocyanate derivatives of fluorescein (FITC) and diiodofluorescein (IFC) were employed: the latter ca... | 511,933 | [
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0.2943475,
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Involvement of membrane calcium in the response of rabbit neutrophils to chemotactic factors as evidenced by the fluorescence of chlorotetracycline. | We have utilized the fluorescent chelate probe chlorotetracycline to investigate the possible involvement of membrane calcium in the response of rabbit peritoneal neutrophils to chemotactic factors. Two chemotactic factors, the small molecular weight fragment of the fifth component of complement C5a and the synthetic p... | 511,938 | [
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-0.2585009,
0.1769626,
0.09619355,
-0.1348819,
0.07934008,
0.154911,
0.05164745,
0.0753787,
-0.2546525,
0.06190168,
0.085765,
0.132674,
-0.1476674,
-0.2381997,
-0.3346431,
0.157522,
-0.2110877,
0.3432209,
0.2771902,
0.2573838,
-0.01670275,
0.00... |
Microsomal T system: a stereological analysis of purified microsomes derived from normal and dystrophic skeletal muscle. | Heterogeneous populations of microsomes obtained from normal and dystrophic chicken pectoralis muscle were separated into two subfractions by an iterative loading technique. The buoyant density of the sarcoplasmic reticulum (SR) microsomes was increased after loading them with calcium oxalate. Several incubations in th... | 511,940 | [
-0.279546,
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0.039324,
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0.09364551,
0.4105829,
0.05133108,
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0.10... |
Inhibition by glucocorticoids and choleragen of the conditional growth of poorly adherent mononuclear phagocytes of newborn hamster liver and lung (hormonal control of macrophage growth). | Conditions for in vitro growth of mononuclear phagocytes from newborn hamster liver and lung were studied. In the primary cultures of liver and lung, round cells outgrew and frequently floated off into the culture medium. They were separated from fibroblast-like cells adherent to plastic by collecting the medium. The r... | 511,948 | [
-0.006715687,
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0.02709129,
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0.3869014,
0.17299,
0.1065467,
-0.3376951,... |
Cholesterol metabolism in diabetes: the effect of insulin on the kinetics of plasma squalene. | The turnover of isotopically labeled squalene formed in plasma from [14C]mevalonate has been used to measure cholesterol synthesis in diabetics over a 7-h period. Five patients were studied while in poor diabetic control (mean daytime glycemia, 349 mg/dl) and at a later date once improved control was established by mul... | 511,973 | [
-0.02772911,
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0.1435825,
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0.4458123,
0.2350263,
0.4080852,
0.2316638,
-0... |
Absence of measurable 2-hydroxyestrone in the rat brain: evidence for rapid turnover. | The free 2-hydroxyestrone content of female rat brains was measured by two independent methods, including a direct radioimmunoassay and enzymatic conversion to stable O-methylated derivatives followed by a specific radioimmunoassay for the latter. The sensitivities of the two procedures were 10 pg and 5 pg respectively... | 511,982 | [
-0.05493879,
0.1527717,
-0.009893959,
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0.08658332,
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0.07649767,
0.1082755,
0.09706458,
0.4015453,
0.09508117,
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0.416929,
0.2140091,
0.1434826,
0.2061325,
0.1722089,
-0.1086232,
... |
A mid-day surge in cortisol levels. | A dramatic mid-day surge of cortisol with its onset concomitant with food intake was observed. Cortisol levels were unaffected by the evening meal. The magnitude and time course of the initiation of this mid-day peak of cortisol are markedly attenuated by food deprivation. These observations establish that within the c... | 511,983 | [
-0.1926342,
0.114258,
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0.0730783,
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0.06906616,
0.168295,
0.1900108,
0.05608729,
0.02352178,
0.05797309,
0.1233856,
... |
Evidence for organicity in concrete vs. overinclusive thought-disordered schizophrenics. | Matched 20 overinclusive schizophrenics, 13 schizophrenics with a concrete thought disorder, defined in terms of performance errors on a conceptual ability test, and 11 brain-damaged patients on age, education, vocabulary proficiency, severity of illness and length of hospitalization. Ss then were given the Combined Te... | 511,992 | [
-0.3333255,
0.3070106,
0.1202611,
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0.3457722,
-0.1938886,
-0.2131415,
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0.1169473,
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0.3121546,
-0.02190708,
0.1774594,
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0.1758033,
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0.09971225,
-0.4532335,
0.1227904,
-0.1171116,
0.09193779,
-0.163779,
... |
Anomie and United States Suicide rates, 1973--1976. | Related annual variations in United States suicide rates between 1973 and 1976 to concomitant annual variations in expressions of anomie obtained on the 5-item Srole anomie scale by a representative sample of the United States population. Expressions of anomie increased significantly for persons in the age groups (15--... | 511,993 | [
-0.5467484,
-0.2630053,
0.08471574,
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0.1881896,
-0.2538203,
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0.1856607,
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-0.12202,
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-0.4652588,
-0.002201518,
0.2750249,
-0.2145228,
-0.002352078,
0.4052081,
0.0688339... |
A comparison of response exaggeration techniques. | Compared the effectiveness of several response exaggeration techniques. Socially anxious college males (N = 34) were instructed to exaggerate some component of social anxiety onset. One group exaggerated their attending to manifestations of their anxiety, two groups exaggerated either a relevant or irrelevant anxiety r... | 512,005 | [
-0.2295763,
0.3234248,
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0.03255145,
0.196749,
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0.3095693,
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0.05104293,
-0.4349071,
0.1810612,
0.2919789,
0.3365698,
0.001957502,
0... |
Ethylene oxide sterilisation--is it safe? | Tests show that ethylene oxide penetrates and can sterilise long narrow tubes in a hospital ethylene oxide steriliser. Residual ethylene oxide levels in plastic tubing after sterilisation have been estimated. Although initially the levels were very high, storage for four days at room temperature reduced them to a safe ... | 512,032 | [
-0.1747151,
0.1625908,
0.1805958,
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0.06904525,
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0.02603109,
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0.05796489,
-0.2333136,
0.03092796,
0.01454445,
0.1682946,
0.03789032,
... |
Occurrence and cultural features of Streptococcus milleri in various body sites. | An investigation was made into the habitat of commensal strains of Streptococcus milleri. These showed distinctive patterns of cultural features, dependent on their sites of origin, which were compared with those prevalent in strains grown from the appendix, 'anal' lesions, and Bartholin's abscesses. A biotype, which s... | 512,036 | [
0.1136168,
0.01237866,
-0.2004121,
-0.04866925,
-0.08479133,
-0.1852797,
-0.3280842,
-0.3611942,
-0.147241,
-0.4400474,
0.1128535,
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0.06008703,
0.2926083,
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-0.07127447,
0.1170013,
-0.1169668,
0.6899236,
0.2110191,
-0.154258,
... |
An inter-laboratory survey of paediatric bilirubin analyses. | A regional quality control trial of paediatric bilirubin analyses is described. The overall performance of the group was unsatisfactory with an unacceptably high inter-laboratory variation. The use of a common standard produced improvement in performance but it is concluded that the poor performance was also due to met... | 512,039 | [
-0.006649035,
0.08702219,
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0.1096141,
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0.05603688,
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0.04074709,
-0.118502,
0.1044829,
0.1942476,
0.01637683,
-0.0398635... |
Immunity in wart resolution. | The involvement of the humoral and cell-mediated immune systems in the regression of wart infection has been investigated extensively in recent years. This review examines the supporting evidence for the roles of humoral and cellular immunity in wart regression and its possible implications. From the available data it ... | 512,079 | [
-0.09246219,
-0.2325648,
-0.3440657,
-0.143209,
0.05121455,
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-0.1948832,
-0.03689352,
0.1424789,
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0.3402297,
0.03945564,
0.07887531,
-0.09372004,
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-0.1126324,
0.03898306,
-0.1657441,
0.1116698,
0.2397442,
0.01666278,
-0.225692... |
Schedule-induced polydipsia suppresses pituitary-adrenal activity in rats. | The effects of schedule-induced polydipsia (SIP) on pituitary-adrenal activity, as indicated by plasma levels of corticosterone, were examined in a series of experiments. Male (Experiments 1 and 3) and female (Experiment 2) rats were reduced to 80% of their free-feeding weight and given daily sessions on an intermitten... | 512,102 | [
-0.1402946,
-0.001969067,
-0.175789,
-0.1738091,
0.1933191,
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-0.01318966,
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-0.0964562,
0.06425833,
0.3104669,
-0.0680089,
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0.1459038,
0.04234426,
0.005514289,
0.1718607,
-0.03427922,
-0.0509... |
Sagittal and coronal image reconstruction: application in pancreatic computed tomography. | The application of coronal and sagittal image reconstruction in the display of the normal pancreas and peripancreatic region is illustrated. The use of standard reproducible reference points for multiplanar reconstruction is suggested. Reconstruction computed tomography displays more anatomic structures in the coronal ... | 512,103 | [
-0.08290105,
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-0.004182836,
-0.2301621,
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0.1800856,
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0.1701664,
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0.06216786,
0.006989415,
0.2182819,
0.1624453... |
Contrast enhancement of the pancreas in computed tomography. | Contrast enhancement of pancreas, liver, kidney, muscle, and blood was measured from computed tomography scans of 46 patients, including patients with normal pancreas (20), pancreatitis (20), and pancreatic carcinoma (6). A bolus injection of contrast agent was given intravenously. Contrast enhancement and contrast dis... | 512,104 | [
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0.2258553,
0.2069314,
0.2064232,
0.1104102,
0.3690114,
-0.04916174,... |
Evaluation of automatic mastitis detection equipment. | An electronic sensor was evaluated as an instrument for early detection of mastitis. This method involved measuring the conductivity of milk continuously throughout the milking process and then establishing a conductivity ratio. The lowest conductivity measurement of the four quarters was a basis for assessing the degr... | 512,133 | [
0.09478168,
0.06407003,
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0.0100133,
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0.2750801,
0.2076425,
0.1568683,
-... |
Measurement of estrogens in cow's milk, human milk, and dairy products. | Free natural estrogens in raw and commercial whole milk were quantitated by radioimmunoassay. The ranges of concentration of estrone, estradiol 17-beta, and estriol were 34 to 55, 4 to 14, and 9 to 31 pg/ml. Proportions of active estrogens (estrone and estradiol) in the fat phases of milk by radioactive tracer on separ... | 512,140 | [
-0.01918101,
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0.3789138,
0.3676158,
-0.07651672,... |
A simple method for incorporating single pass dialysate delivery and controlled ultrafiltration with the RP-6 high flux dialyzer. | A simple hemodialysis protocol has been developed to permit significant "middle molecule" clearance, yet retain normal low molecular weight clearance. The high flux RP-6 dialyzer has been combined with a single pass dialysate delivery system to provide accurate control of ultrafiltration without resorting to specialize... | 512,178 | [
-0.2790896,
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0.01398368,
-0.1749856,
0.1281603,
0.09677008,
-0.0774008,
... |
Comparison of the spectra of the cochlear microphonic and of the sound-elicited electrical impedance changes measured in scala media of the guinea pig. | The harmonic structure of the cochlear microphonic (CM) and that of a sound-elicited signal which we have considered as an (apparent) changing resistance (CR) were simultaneously determined in scala media of the first turn of the guinea pig cochlea. We analyzed our data in the context of the Davis variable resistance h... | 512,204 | [
-0.02206404,
-0.3361306,
-0.3461554,
-0.1472674,
0.1506745,
-0.1604163,
-0.294324,
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-0.1054428,
-0.525108,
0.007463466,
0.2710238,
-0.2233365,
0.1004647,
... |
Relationship between airways response to allergens and nonspecific bronchial reactivity. | Bronchial inhalation challenges to histamine, methacholine, and at least one antigen were performed on 183 asthmatic patients who previously had received skin tests to at least 16 different antigens. Individuals with a positive skin test and a positive antigen inhalation challenge to the same antigen had lower threshol... | 512,267 | [
0.06755061,
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-0.07679942,
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-0.08987157,
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0.1874394,
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0.07245923,
0.05309728,
0.2055185,
0.03189905,
-... |
Epidemiology of hyperuricemia in an ambulatory elderly population. | The relationship of serum uric acid concentration to age and sex was assessed in 1,701 participants in a geriatric multiphasic screening clinic. Included were 1,067 women and 634 men. The mean uric acid level for men was 6.35 mg/100 ml compared to 5.44 mg/100 ml for women. No statistically significant increases in seru... | 512,283 | [
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-0.09406988,
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-0.06078409,
-0.0590088,
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0.06104401,
0.28019,
0.1217843,
-0.1826958,
0.06462382,
0.3768367,
-0.06785799... |
Life changes and perceptions of life and death among older men and women. | Although social scientists have suggested that feelings about life and death may be related, for the most part, theories of social gerontology have developed independently of conceptions of death and finitude. This study examines whether life changes are associated with concurrent life and death attitude types among ol... | 512,307 | [
-0.09064069,
-0.06683589,
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0.2411026,
0.3459695,
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-0.2821899,
0.06010811,
0.319903,
-0.2733476,... |
A fluorescent assay of proteinases in cultured mammalian cells. | We have demonstrated proteinase activity in unfixed cells grown on tissue culture plates with a technique using 5-nitrosalicylaldehyde and peptide derivatives of 4-methoxy-2-naphthylamine. The 4-methoxy-2-naphthylamine liberated by proteinase activity reacts with 5-nitrosalicylaldehyde to form a fluorescent product. Th... | 512,330 | [
-0.1495667,
-0.3318062,
-0.3015006,
0.1297964,
0.1065353,
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-0.2579925,
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0.1494931,
0.02689718,
0.4183273,
0.5416467,
0.3622905,
0.09781041,
-... |
Freezing of tissue-limits for the autoradiographic localization of diffusible substances. | Frozen thin sections and sections from freeze-dried and embedded tissue are used for the autoradiographic localization of diffusible substances at the electron microscope level. The presence of ice crystals in such sections may limit the autoradiographic resolution. Ice crystals are formed during freezing and may grow ... | 512,336 | [
-0.1326901,
0.0371544,
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0.02269659,
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0.3639427,
0.2739391,
0.1899198,
-0.3074082,
... |
Potential risk of salivary-mediated viral hepatitis type B transmission from oral exposure to fomites. | Twelve grade school and junior high school students had oral exposures to hepatitis B surface antigen (HBsAg) positive saliva via contact with contaminated musical instruments. The 12 exposed students and 18 students who served as age and sex matched controls were tested for the presence of HBsAg and antibody to the he... | 512,356 | [
-0.1952025,
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-0.08538161,
0.09139878,
0.2175457,
-0.2650878,
... |
Laboratory breeding of the European rabbit flea, Spilopsyllus cuniculi (Dale). | A method is described for the laboratory breeding of the rabbit flea in which the immature stages are reared at constant temperature and humidity. Eggs are obtained by confining fleas taken from a rabbit and her nest shortly after parturition with two of her nestlings in an incubator for 24 h. The eggs are transferred ... | 512,357 | [
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0.003775496,
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0.154327,
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0.01681079,
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0.1121542,
-0.0200807,
-0.2592765,
0.5114553,
-0.2048446,
... |
Crossed radioimmunoelectrophoresis for the analysis of lymphocyte surface antigens. | A sensitive crossed radioimmunoelectrophoreses technique is described as a model tool for studying lymphocyte surface antigens, using Triton X-100 solubilized sufface radiolabeled human peripheral blood lymphocytes as the antigen source and experimental antiserum produced by hyperimmunization of rabbits as the antibod... | 512,364 | [
-0.02672858,
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0.03694448,
0.2064872,
0.08829593,
-0.04873218... |
Abnormal proliferation of uninvolved psoriatic epidermis: differential induction by saline, propranolol, and tape stripping in vivo. | Cell proliferation of the uninvolved psoriatic skin was compared with normal skin of volunteers following stimulation by the intradermal injections of saline or propranolol, or stripping of the stratum corneum with pressure-sensitive tape. Initially, no significant in vivo difference in tritiated thymidine labeling ind... | 512,406 | [
0.09114604,
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-0.08173545,
0.1475999,
-0.2918893,
-0.03420584,
-0.08555975,
-0.1278086,
0.3887909,
-0.297837,
0.2221012,
-0.2916175,
-0.09632845,
-0.3230037,
0.05014689,
0.2619407,
0.3015607,
-0.106865... |
Multiple forms and glycoprotein nature of acid phosphatase, alpha-fucosidase and alpha-mannosidase of psoriatic scales. | Isoelectric focusing and concanavalin A-Sepharose chromatography were used to study the multiple forms and glycoprotein natures of so-called lysosomal hydrolases from psoriatic scales. Acid phosphatase appeared as 5 different forms with pI values of 6.5, 6.1, 5.8, 5.6 and 5.45. Seven isoenzymes of alpha-fucosidase were... | 512,407 | [
-0.1517612,
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0.2463554,
0.2506066,
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0.1354124,
0.1808104,
0.140077,
0.1979989,
0.1267442,
-0.5373732,
-0.... |
The influence of dosage regimen on experimental gentamicin nephrotoxicity: dissociation of peak serum levels from renal failure. | Peak serum levels of gentamicin were varied in rats by administering a standard nephrotoxic dosage of 40 mg/kg per day in one (QD), two, or three (TID) daily doses. The QD animals had the highest peak serum levels but showed no appreciable increase of serum creatinine concentrations over a 10-day treatment period. The ... | 512,417 | [
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0.03815885,
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-0.06828374,
-0.1606137,
0.1795767,
0.07198361,
0.1245561,
0.1221428,... |
Mortality of steelworkers employed in hot jobs. | This paper investigates possible relationships between heat stress of steelworkers and cause-specific mortality patterns. Prior to field investigation, jobs were identified which appeared to involve heat stress exposure. A selected sample of these jobs was surveyed for assessing the workers' environmental and metabolic... | 512,565 | [
-0.3440181,
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0.06547063,
0.1071701,
0.1330124,
0.3130175,
0.1958039,
0.688499,
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0.0... |
Oscillatory membrane potential changes in cells of mesenchymal origin: the role of an intracellular calcium regulating system. | A number of mesenchymal cells (fibroblasts, macrophages and megakaryocytes) respond to a variety of stimuli with large hyperpolarizations lasting several seconds (the H.A. response). The H.A. responses can occur as repetitive trains or oscillations. These hyperpolarizations are due to an increase of the surface membran... | 512,579 | [
-0.362211,
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-0.1501054,
-0.0383056,
0.3507259,
-0.1387056,
-0.0728287... |
Determination of sex by discriminant function analysis of postcranial skeletal measurements. | Thieme and Schull [16] took measurements of seven postcranial traits from black skeletons of known sex to devise a method for accurately sexing human remains. With a linear discriminant function analysis of the data they obtained a 98.5% accuracy. The research reported here was designed to assess the accuracy of their ... | 512,599 | [
0.1031896,
0.3329736,
0.03567731,
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0.08716492,
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0.4687487,
0.2772791,
-0.1946271,
-0.2701806,
... |
Determination at the nanogram range of rilatinic acid in urine after ion-pair extraction. | Ion-pair extraction and extractive alkylation of urine allows a simple, rapid, and very sensitive detection by TLC as well as EC-GLC tecnhiques, of rilatinic acid in small urine samples after the oral intake of therapeutic doses of methylphenidate. | 512,616 | [
0.0913802,
0.07767675,
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0.312788,
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0.01799677,
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0.2742837,
0.05157473,
0.1954041,
0.3774008,
0.1356061,
0.08784634,
... |
The structure and function of serially homologous leg motor neurons in the locust. II. Physiology. | Simultaneous intracellular recordings were made from pairs of motor neurons in the pro- or mesothoracic ganglion of the locust. Though central connections were sought between pairs of motor neurons, none were found. This is in sharp contrast to the findings that flexor and extensor tibiae neurons in the metathoracic ga... | 512,655 | [
0.262927,
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0.1794742,
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0.1117984,
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0.0795948,
0.1682529,
0.2165063,
-0.02323312,
0.1585324,
... |
Autophosphorylation of chick brain synaptic polypeptides. Phosphorylation of proteins during incubation of intact synaptosomes with 32PO4. | Chick brain synaptosomes incorporated phosphate into proteins when incubated in physiological buffer containing energy sources. Sodium dodecyl sulfate polyacrylamide gel electrophoresis indicated that three synaptosomal polypeptides were significantly phosphorylated after 15 sec incubation while at least fifteen polype... | 512,656 | [
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0.3372618,
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0.1958632,
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-0.06826583,
0.2953523,
0.1221335,
0.2140436,
-0.01227849... |
Reduction of methemerythrin-anion adducts by dithionite ion. | The reduction by dithionite ion (in excess) of methemerythrin-anion adducts, Hr+X-, to deoxyhemerythrin, Hr degree, has been examined at 25 degrees and pH 6.3 and 8.2. The results accord with the scheme: S2O42- in equilibrium 2SO2- rapid Hr+X- in equilibrium Hr++X- k-1, k1 Hr++SO2- leads to PRODUCT k2 with X- = Br-, HC... | 512,658 | [
-0.2573992,
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0.1795508,
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0.006747276,
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0.03364319,
0.007340217,
0.04112642,
0.2728763,
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0.2820023,
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-0.3888064,
0.1636958,
0.4745832,
0.2413965,
0.1485404,
0.02155225,
-0.1079942... |
Abnormalities of cerebrospinal fluid amino-acids in purulent meningitis. | Serial measurements were made of the cerebrospinal fluid and plasma amino-acid concentrations in 12 patients with purulent meningitis. Marked increases in the concentrations of most CSF amino-acids were found, possibly caused by altered transport mechanisms in the inflamed meninges and choroid plexuses. | 512,663 | [
-0.0813472,
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0.006122608,
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0.09929341,
0.09707398,
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0.343841,
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0.03997879,
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0.05713538,
0.2660483,
-0.04827384,
0.1075958... |
Recurrent demyelination in chronic central nervous system infection produced by Theiler's murine encephalomyelitis virus. | A morphologic study of demyelination produced by Theiler's encephalomyelitis virus (TMEV) infection in C3H/He mice was performed. Demyelination in this strain of mouse was less intense and had a milder gliomesodermal response than that observed in SJL mice. As early as 80 days after infection numerous remyelinated axon... | 512,673 | [
0.1706552,
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0.1013297,
0.1612785,
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0.05024962,
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0.225908,
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0.4311898,
0.1752972,
0.2985019,
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0.05452072,
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-0.01224441,
0.04828671,
0.3094133,
-0.006889668,
... |
Degenerative changes at the neuromuscular junctions of red, white and intermediate muscle fibers. Part 1. Response to short stump nerve section. | Degeneration at the neuromuscular function following cutting the phrenic nerve at the 9th intercostal space differs in red, white and intermediate skeletal muscle fibers. The ultrastructure of the nerve terminal and the muscle fiber between 12 hours and 21 days following denervation suggests that lack of neurotrophic i... | 512,680 | [
-0.03616122,
-0.1364895,
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0.2291835,
0.2254293,
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0.1760276,
0.219951,
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-0.690573,
-0.2889319,
0.1807666,
-0.1211209,
0.3659629,
0.4723926,
0.2591791,
... |
Chronic form of childhood spinal muscular atrophy. Are the problems of its genetics really solved? | The authors discuss the differences between the two large series of chronic childhood spinal muscular atrophies (SMA)--their own comprising 273 cases, and that of Pearn et al. comprising 141 cases. The main difference concerns the predominance of males in the clinically milder later-onset group in the present series. T... | 512,685 | [
-0.02314916,
0.02349936,
0.1057132,
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0.1089542,
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0.1081218,
0.0526657,
0.1595466,
0.2084902,
0.2884796,
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0.166685,
0.09977791,
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0.2653485,
0.3516486,
0.1410657,
-0.2643733,
0.036... |
Peripheral intraaxonal storage in Tay-Sachs' disease (GM2-gangliosidosis type 1. | Considerable intraaxonal lipid storage was observed in intramuscular nerve fibres mainly of the extraocular muscles and less frequently in limb muscles of a 3-year-old child, which had suffered from Tay-Sachs' disease. Many axons of the small intramuscular nerve twigs and of the terminal and preterminal nerve endings s... | 512,688 | [
-0.1979326,
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0.1590404,
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0.147812,
0.1050624,
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0.01163272,
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0.05923891,
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-0.008930887,
0.4024864,
0.5579011,
0.1865218,... |
Normal human aging and cerebral vasoconstrictive responses to hypocapnia. | Cerebral vasoconstrictive capacitance was measured during voluntary hyperventilation hypocapnia in 22 healthly normal volunteers aged 21--65 years by serial 133Xe inhalation estimates of rCBF by the initial slope index method of Risberg (ISI2) in the steady state followed by the hypocapnic state. End-tidal PCO2 was mon... | 512,693 | [
0.01923462,
0.1363816,
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0.2631719,
0.05710357,
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0.1023941,
0.1824167,
0.1114011,
0.2215325,
0.2508542,
... |
Adipocyte cholesterol storage: effect of experimental hypercholesterolemia in the rat. | In order to more clearly define the influence of adipocyte size and plasma cholesterol on adipose tissue cholesterol storage, hypercholesterolemia was induced in male Fisher rats at a time when body weight and adipocyte size become fixed. In one experiment (experiment 1), increasing amounts (0, 0.05, 0.5 and 5.0%) of d... | 512,709 | [
0.2019172,
0.3587961,
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0.09453616,
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0.3497894,
0.09897681,
0.08656194,
0.2521293,
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0.002515801,
0.04747181,
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0.014857,
-0.1920097,
-0.07349812,
0.2050588,
0.06902026,
0.2522724,
0.01322309,... |
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