title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Ultrasound appearance of myositis ossificans. | Ultrasonic evaluation of a soft tissue mass of the thigh was performed and suggested the diagnosis of myositis ossificans. Correlation with routine radiographic studies is made, as well as with the follow-up radiographic examination. | 515,745 | [
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Osgood-Schlatter's disease, an emphasis on soft tissue changes in roentgen diagnosis. | Osgood-Schlatter's disease is a well known entity affecting the adolescent knee. Radiologic examination of the knee has been an integral part of the diagnosis of this condition for decades. However, the soft tissue changes have not been appreciated sufficiently. Emphasis is placed on the use of optimum radiographic tec... | 515,746 | [
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Periosteal bone apposition in chondroblastoma. | Periosteal bone apposition in chondroblastoma of long bones is more frequent than generally recognized. This should not cause confusion in differential diagnosis. The findings does not seem to have prognostic significance. | 515,749 | [
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The effect of intravenous domperidone on the resting lower oesophageal sphincter pressure in dogs and baboons. | Domperidone (Motilium), a dopamine receptor blocking agent, increased the resting tone of the lower oesophageal sphincter in 15 dogs and 6 baboons. It is therefore a potentially useful drug in the management of gastrooesophageal reflux due to incompetence of the lower oesophageal sphincter. | 515,866 | [
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Porphyria and the dangerous life-threatening drugs. | The dangerous life-threatening drugs have been identified in 153 acute attacks in 138 porphyric patients by establishing a consistent temporal relationship between the administration of a specific drug and the development of an acute attack. The drugs so identified have been supplemented by a number of others found to ... | 515,871 | [
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Gycosuria as an indication for glucose tolerance testing during pregnancy. | The indications for and results of all glucose tolerance tests (GTTs) performed at the Antenatal Clinic, Groote Schuur Hospital, Cape Town, over a period of 1 year, and the indications for a GTT in the first 80 newly diagnosed diabetics over a 4-year period are analysed. Out of 558 GTTs, only 17 tentative diagnoses of ... | 515,873 | [
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Benign tumours of the larynx. | Over the 8-year period 1971--1978, 743 benign lesions of the larynx, of which 551 were pseudotumors and 192 were benign neoplasms, were surgically treated at Groote Schuur Hospital. In comparison, during the same period 402 malignant tumours of the larynx were also seen. The commonest benign lesions were vocal cord nod... | 515,875 | [
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Costs in a clinical pharmacological laboratory. | As a measure of the efficiency of service provided to the Groote Schuur group of hospitals by the Department of Clinical Pharmacology, certain costs were analaysed. The approximate annual cost of routine analytical work was R40 000 $45 000 or 22 000 pounds). The average cost per assy was R9,50 ($11,30 or 5,50 pounds). ... | 515,880 | [
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Hearing impairment: a family crisis. | This paper reviews the initial crisis for hearing impaired children and their families from the perspective of the clinician who must assess their adjustment at the point of entry into a school for the deaf. The use of crisis theory as it relates to the special needs of this client group is discussed. | 515,888 | [
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Sensitivity patterns for the induction of homeotic shifts in a favorable strain of mice. | In an effort to develop a prescreening system that is sensitive, is compatible with in-vivo administration of presumptive teratogens, and utilizes morphological endpoints, we are studying the induction of homeotic shifts in the axial skeleton. Our earlier work had demonstrated the existence of critical periods for cert... | 515,957 | [
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Histocompatibility antigens in asthma: population and family studies. | One hundred and twenty-two patients with intrinsic asthma, extrinsic atopic asthma, or asthma with allergic bronchopulmonary aspergillosis were tissue typed for the HLA A, B, and C loci. No associations were found with any of the clinical groups, or with serum total IgE concentrations. Sixty-eight members of 10 familie... | 515,989 | [
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[Investigations into the clinical significance of beta-glucuronidase as tumour indicator during radiation therapy of patients with carcinoma of the bladder (author's transl)]. | We examined the activity of beta-glucuronidase in serum and urine in two different patient groups with carcinoma of the bladder. In one group the tumour was excised totally, in the other group tumour material was left. There was no correlation to be found between extension of the tumour and enzyme activity, or between ... | 516,097 | [
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RBE of d(50)-Be neutrons for induction of chromosome aberrations in Allium cepa onion roots. | RBE/absorbed dose relationship of d(50)-Be neutrons was determined for the induction of chromosome aberrations in Allium cepa onion roots. Neutrons are produced at the cyclotron "Cyclone" by bombarding a thick beryllium target with 50 MeV deuterons. Two biological criteria were selected: (1) mean number of aberrations ... | 516,100 | [
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Effect of cystamine on rat tissue GSH level and glutathione reductase activity. | Reduced glutathione (GSH) level and glutathione reductase activity were determined by means of the spectrophotometric method in various rat tissues after i.p. administration of cystamine (50 mg/kg and 20 mg/kg). GSH amount dropped in the spleen and kidney at 10 and 20 min; following this interval, an increase of GSH le... | 516,110 | [
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Rat thymic dihydrotestosterone receptor: preparation, location and physiochemical properties. | Castration in the male rat has been shown to produce enlargement of the thymus gland while treatment with dihydrotestosterone (DHT) results in a decrease in thymic size in these animals. To determine if these changes might be receptor mediated, thymus tissue from castrate male rats was removed and homogenized in buffer... | 516,117 | [
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[Antibody-dependent cytotoxic activity of the lymphocytes and the cytological characteristics of immune cell complexes in vitro]. | Bovine blood lymphocytes showed a high antibody-dependent (AD) cytotoxicity against target cultured L cells. The cytological analysis of immune cellular complexes, formed by affector lymphocytes with target cells during the cytotoxic reaction in vitro, revealed that adsorption of AD lymphocytes to target cells was comp... | 516,166 | [
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[Ultrastructural equivalents of postburn anuria]. | Dystrophic and degenerative disturbances in tubular epithelium are established by electron microscopy. Ultrastructural changes suggested that transport mechanisms in the proximal tubule are enhanced by cytoplasm vesiculation and dilation of intercellular spaces. Transepithelial pinocytosis is the basic process in dista... | 516,162 | [
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[UV-sensitive mutants of Streptomyces olivaceus VKX]. | 14 UV-sensitive (uvs) mutants of S. olivaceus VKX isolated by replica-plating technique among 45780 survivors after the induction of mutations nitrosoguanidine or UV (about 0.03%). The sensitivity of uvs-mutants to UV-irradiation was 5-10 times higher than in the initial strains and in 4 uvs-mutants it was 100 and more... | 516,163 | [
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[Peculiarities of histones H1, H2b and H4 structure and aggregation in the presence of glycine]. | The efficiency of intramolecular and intermolecular interactions of histons H1, H2b and H4 was studied as affected by the glycine concentration in the composition of the glycine-HCl buffer (pH 3.0). It is shown that the concentration of glycine less than 0.01m should be used in experiments with the glycine buffer. Glyc... | 516,180 | [
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[Therapeutic procedure in severe craniocerebral trauma combined with skeletal injuries in children]. | The article is devoted to a complex and scantily explored problem of treatment of patients with a severe cranio-cerebral injury in the acute period. The analysis of a considerable material (129 cases) showed the early and valuable treatment of fractures of skeletal bones to have favourable effect upon the course of the... | 516,259 | [
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[Adhesive processes in large and huge postoperative ventral hernias]. | High incidence, severity and wide distribution of adhesive processes affecting the abdominal organs and the content of the hernial sacs in 250 patients with big and great postoperative ventral hernias were closely associated with the features, clinical manifestations of the disease and character of treatment. The autho... | 516,272 | [
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A probable congenital diaphragmatic defect in an adult pony. | The presenting signs exhibited by a pony with a large diaphragmatic defect of probable developmental origin are described. The results of clinical examination, laparotomy and post mortem examination are presented. | 516,300 | [
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[Encephalomalacia in partridges, quails and pheasants raised in warrens]. | With the introduction of industrial methods of breeding game animals, resp., birds in confinement some new diseases have arisen, such as encephalomalacia. Due to its peculiar character this disease was first referred to as B-complex avitaminosis, respective therapeutic measures being taken. Recent studies have ruled ou... | 516,445 | [
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[Effect of cooling on liver phospholipids]. | Phospholipid composition of rat liver tissue was distinctly altered in cooling. Single-term cooling caused a decrease in content of phosphatidic acids, cardiolipin, phosphatidyl diethanolamine, phosphatidyl serine but it increased the sphingomyelin level. Content of phosphatidyl choline and of lysolecithins was markedl... | 516,527 | [
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[Enzymatic activity in the enterolysed portions of the human gastric mucosa in peptic ulcer and the effect of bile]. | Activities of lactate dehydrogenase /LDH/, glucose-6-phosphate dehydrogenase /G6PD/, transaminases, alkaline phosphatase as well as content of lactic acid were studied in enterolysed parts of gastric mucose and in normal mucose. The LDH activity and content of lactic acid were decreased in the enterolysed mucose. As co... | 516,530 | [
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[Mechanism of the change in energy and electrolyte metabolism in the respiratory musculature in experimental botulism]. | Distinct decrease in concentrations of creatine phosphate and K+ was observed in various respiratory muscles of cat in generalized botulism, accompanied by the syndrom of asphyxia. Content of glycogen and Na+ was unaltered in these cases. In local botulinic paralysis concentrations of creatine phosphate, glycogen and K... | 516,537 | [
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[Isolation of cathepsin D from the aorta using pepstatin sepharose]. | Affinity chromatography on pepstatin-Sepharose was used for isolation of cathepsin D from pig aorta. The enzyme was purified 800-fold. The proteolytic activity of cathepsin D was completely inhibited by pepstatin, suggesting that there were no other proteinases in the enzyme preparation obtained. | 516,535 | [
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[Various cellular immunity indices in patients with esophageal cancer]. | It was found that 75.8% of patients with esophageal cancer respond positively to percutaneous injection of the antigen polysaccharid fraction. In patients with esophagitis the positive reaction was noted in 25% of cases. The rosette-forming capacity of lymphocytes is suppressed in 91.2% of patients with esophageal canc... | 516,576 | [
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[Clinico-radiological features of incipient esophageal cancer]. | One hundred and five patients with esophageal cancer were observed. A retrospective analysis has shown that clinico-radiological examination associated with fiberoptic esophagescopy failed to reveal any typical clinical manifestations of early esophageal cancer. The diagnosis at early stages of the disease is possible ... | 516,577 | [
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0.1... |
[Causes for refusing surgical treatment among gastric cancer patients]. | The data on 26 gastric cancer patients who refused to be treated at different Moscow City hospitals are reported. A questionnaire method was employed to study the cause of such refusals. Some practical recommendations are given to reduce the number of the latter. | 516,585 | [
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0.... |
[Surgical treatment of benign bone neoplasms and its results]. | The results of treatment of 404 patient with benign bone tumors are analysed, in 232 of them tumors being of osteogenic origin and in 172--of cartilaginous one. 382 patients were subjected to surgery. Late results of the treatment were studied in 313 (77%) patients. The recovery was noted in 297 (94.9%) patients, the r... | 516,586 | [
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0.03365898,
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... |
[Effect of time of administration of food supplement amino acids on protein utilization and the body composition of rats]. | The effect of administration of amino acids enriching the diet on protein utilization and rat body composition was investigated. Net protein utilization (NPU) of the diet enriched by tryptophane, lysine or sulphur-containing amino acids comprised 0.408, 0.335 and 0.664. Changes in the time of administering the amino ac... | 516,595 | [
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0.09004565,
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0.3052808,
-0.136703... |
[Heterogeneity of the kappa-casein glycomacropeptide and physiological activity of its fractions]. | A number of fractions with differing intensity of the inhibitory action on the gastric secretion were obtained by gel filtration in a column with biogels P-30 and P-2 of cappa-casein glycomacropeptide. A low-molecular fraction displays the greatest capacity for inhibiting gastric secretion. Desialism, heating and parti... | 516,596 | [
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[Food and biological value of the adapted acidophilous mixtures, Maliutka and Malysh]. | The new acidophilus liquid mixtures "Malyutka" and "Malysh" manufactured under industrial conditions were subjected to comprehensive physicochemical, microbiological and biological studies. Amino acids and fatty acids contained by the mixtures as well as their biological value were also examined. | 516,609 | [
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[HL-A and ankylosing spondylarthritis]. | With the investigation of HL A phenotypes of 133 patients with an akylozing spondylarthritis, 110 males and 23 females, confirmed incidence of antigen B 27 was established in 87.96 per cent versus 10.78 per cent of 1085 control healthy subjects. The families of 24 patients were also examined with a total of 27 subjects... | 516,653 | [
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Suicide in general hospitals. | Of 14 medical and surgical patients who committed suicide in a general hospital, there were ten men and four women, ranging in age from 19 to 82. The patients had not made statements of suicidal intent; however, their hospital records showed there had been symptoms of depression and contained indirect references to a p... | 516,665 | [
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Functional overlay: an illegitimate diagnosis? | Functional overlay is not a recognized psychiatric diagnosis. Evaluating functional overlay and differentiating between this concept and organic conditions is important in medicolegal areas in which financial values are placed on pain and disability. Functional overlay is not malingering: the former is based on precons... | 516,698 | [
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Cimetidine treatment of acute and chronic Zollinger-Ellison syndrome. | Thirteen patients with Zollinger-Ellison syndrome (ZES) were treated with cimetidine. This population could be divided into chronic forms, mostly presenting as a common duodenal ulcer, and acute forms resulting in critical problems requiring intensive medical care. Among the 7 patients with chronic ZES, cimetidine trea... | 516,777 | [
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... |
The metabolism of nitrophenolic and 5-arylazorhodanine anthelmintics by Ascaris suum, Moniezia expansa and by mouse- and sheep-liver enzymes. | 1. The anthelmintics disophenol (2,6-diiodo-4-nitrophenol), nitroxynil (3-iodo-4-hydroxy-5-nitrobenzonitrile) and nitrodan (3-methyl-5-(4-nitrophenylazo)rhodanine) were reduced in vitro to the corresponding amines by intact Ascaris suum, Moniezia expansa, by enzymes prepared from these helminths, and by mouse- and shee... | 516,789 | [
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... |
Inhibition by glycine of the catabolic reduction of proline in Clostridium sticklandii: evidence on the regulation of amino acid reduction. | The growth of Clostridium sticklandii on the substrate pair L-alanine-L-proline (reductant-oxidant each 40 mM) in a medium containing 2 g/l yeast extract was completely inhibited by equimolar amounts of glycine, although glycine itself should be used as oxidant by the cells. The effect of glycine was the same, whether ... | 516,795 | [
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-0... |
[Present state and further development of bronchology in the GDR (author's transl)]. | Bronchoscopy and bronchography are further important diagnostic methods in lung diseases. Their development to a high level was influenced by the construction of Friedel's bronchoscope. In the future it will be necessary to extend these methods to general hospitals under special pressuppositions. | 516,808 | [
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-0.1716676... |
[Efficacy of systemic rehabilitation in patients with myocardial infarct--a 4 years' study]. | Form and results of the rehabilitation of patients with myocardial infarction during and after clinical treatment are described in a 4-year-study. According to the form a system rehabilitation is concerned. It comprises a continuous course of early mobilisation during clinical treatment, immediately following group exe... | 516,836 | [
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... |
[Effect of phenoxybenzamine on the renal and general circulation in the hypovolemic hypotonic dog]. | For the estimation of the haemodynamic and metabolic effect of 1 mg/kg phenoxybenzamine in a kidney donor with craniocerebral trauma model experiments were performed on dogs with hypovolaemic hypotension. The results show that phenoxybenzamine leads to vasodilatation in a constant aortic pressure of 80 mm Hg in the sys... | 516,924 | [
-0.09597231,
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... |
[Localization of the receptors that initiate and maintain flight in the cockroach, Periplaneta americana]. | Using local air streams, screening and surgical removal of the cerci and antennae, studies have been made on the receptors which provide for initiation and maintenance of the flight in the cockroach. It was shown that in suspended insect which lacks any contacts of legs with the base, the flight may be initiated by dir... | 516,944 | [
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0.07722159,
... |
[Epidemic of influenza A (H1Ni), 1977--1978]. | The work deals with the peculiarities of the spread of influenza A/USSR77 (H1N1) in the USSR and in the world. The authors point out that the most outstanding feature of the epidemic in the USSR was low morbidity rate among adults, persons aged up to 25 years being most affected. This suggests the existence of prolonge... | 516,952 | [
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0.3387994,
0.2468694,
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0.0892... |
Quantum chemical interpretation of the spectral properties of the CO and O2 complexes of hemoglobin and cytochrome P-450. | The electronic transitions of CO and O2 complexes of hemoglobin and cytochrome P-450 were calculated using a PPP method extended for metal complexes. The calculations show that the unusual spectral properties of cytochrome P-450 are very sensitive to the iron-sulfur bond distance. It is suggested from these calculation... | 517,008 | [
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-0.004584778,
-0.0528497... |
The screening value of the amylase-creatinine clearance ratio in acute pancreatitis. | The screening value of the amylase creatinine clearance ratio in acute pancreatitis is studied. A series of 28 patients with pancreatic disease is compared with 80 controls and 82 patients with other intra-abdominal disease. The greatest specificity of the amylase creatinine clearance ratio value is reached at the 3.5 ... | 517,018 | [
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0.0714451... |
The effect of pregnancy and lactation on pituitary prolactin-secreting tumours. | Management of the amenorrhoea-galactorrhoea syndrome due to pituitary tumour is still controversial. However, in cases of pituitary prolactin-producing adenomas, ovulation and pregnancy are readily induced medically with bromocriptine. In our series of 14 patients conception occurred in all cases within 6 months of tre... | 517,046 | [
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... |
TSH synthesis and release in the thyroidectomized rat: b) effect of T3. | The time and dose dependent effects of T3 on the anterior pituitary (AP) TSH release and synthesis were studied in rats 5 days after thyroidectomy (T-5d). T3, in various doses, was injected iv to animals which were kileed at various times later. Plasma and AP TSH were measured. T3 lowered plasma TSH to a minimum within... | 517,051 | [
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... |
Unusual heterozygotes of congenital adrenal hyperplasia due to 21-hydroxylase deficiency confirmed by HLA tissue typing. | In a previous publication, three relatives of patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency from two families were considered to be unusual heterozygotes rather than homozygotes with mild clinical manifestations. Their heterozygosity could now be confirmed by HLA tissue typing. | 517,053 | [
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0.2773586,
-0.2654605... |
[Lung function studies with the bronchodilator terbutaline]. | The acute bronchodilator effect of the beta 2-adrenoceptor agonist terbutaline was tested single-blind cross-over in out-patients with chronic obstructive airways disease (intrinsic asthma). In 7 series comparisons were made with other marketed bronchodilators. Airways resistance was measured by whole body plethysmogra... | 517,068 | [
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... |
[Morphology of coronary vessels in coronary heart disease. An analysis of 930 coronary angiograms]. | Coronary anatomy was analyzed in 930 patients who underwent coronary arteriography because of coronary artery disease. There was a slight predominance of single vessel disease, whereas double and triple vessel disease were equally distributed. A left main (LM) lesion was found in 5.2%, with an additional right coronary... | 517,069 | [
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0... |
A fluorescence energy transfer system for studying the functional properties of chromatin. | 3YI-B-1 rat embryo fibroblasts were used for double fluorescent labeling. The labeling was carried out with fluorescamine and ethidium bromide as an energy donor-acceptor pair. The fluorimetric measurements proved the existence of an energy transfer process. The parameters of this transfer depended on both cell and dye... | 517,107 | [
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IgG subclasses, barrier function for albumin and production of immunoglobulin G in the central nervous system. | Cerebrospinal fluids from patients with neurological diseases have been studied. It appeared that the detectability of immunoglobulin G subclasses 1, 2, 3, 4, and the occurrence of oligoclonal bands in the IgG region increased with increasing concentration of IgG in the spinal fluid. No specific pattern emerged in the ... | 517,112 | [
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... |
Juvenile amyotrophic lateral sclerosis. A report of two cases in a single family. | This paper presents two juvenile cases of familial amyotrophic lateral sclerosis. They are the first and fourth child in a family with seven children from the eastern part of Finland. All seven children, as well as the parents, were examined by our group. In the first case the disease showed a rather mild course, while... | 517,116 | [
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Vasoconstriction of external carotid arteries after rupture of intracranial aneurysms. | Vasoconstriction of the external carotid arteries, which has not been previously reported, was investigated angiographically in 23 patients who had intracranial vasospasm after aneurysm rupture. In about 50% of these patients vasoconstrictive change in the external carotid arteries was also found. These changes were no... | 517,197 | [
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0.04865206,
0.1511745,
0.06412736,
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0.01871316,
... |
The transmission and acquisition of values in the residential treatment of emotionally disturbed adolescents. | A discussion about (1) the role of values in adolescent development and (2) the various value pathologies found in adolescents in residential treatment was presented. A descriptive study of the transmission and acquisition of three values described how values are not only transmitted by unvarying routines, decrees, tra... | 517,219 | [
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The kinin-forming acid protease system in murine fibroblasts L-929. | Components of an acid protease kinin-forming enzyme system were isolated and purified from the murine fibroblast L-929 cell line grown in stationary cell culture. The enzyme, was purified from the 10,000 g supernatant cell fraction by sequential passage through G-200 Sephadex, hydroxylapatite, DEAE-A50 Sephadex and aff... | 517,235 | [
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Molecular mechanisms of surface-dependent activation of Hageman factor (Factor XII). | Based on studies using 3H-DFP as an active site titrant, it is suggested that surface binding in itself does not result in the formation of new active sites in the Hageman factor molecule. Moreover, it was found that surface-binding of human and bovine Hageman factor renders these molecules 100 to 1000 times more susce... | 517,240 | [
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Partial purification of prorenin and activation by kallikreins: a possible new link between renin and kallikrein systems. | With the objective of identifying prorenin and its physiological activation mechanism, human plasma prorenin was completely separated from active renin for the first time. It was shown that prorenin has no activity whereas active renin has no potential for further activation. Urinary kallikreins were found to activate ... | 517,242 | [
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Variation of urinary kallikrein excretion during pregnancy and the effects of hypertension. | In normal pregnant women the excretion of urinary kallikrein diminishes between the second and the third trimester and such reduction is maintained during the first ten days of puerperium. A comparison between normal women and those suffering from hypertension during the first, second and third trimester of pregnancy s... | 517,257 | [
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Homologous insemination with the addition of pancreatic kallikrein. | Hog pancreatic kallikrein does improve sperm motility and sperm migration in vitro. Kallikrein can be used for artificial insemination to improve cervical mucus sperm penetration ability of spermatozoa with reduced motility. Homologous insemination in 52 couples during a period of one year yields a conception rate of 3... | 517,261 | [
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Autoradiographic studies on the cellular localization of GABA and beta-alanine uptake by neurones and glia in tissue culture. | Nervous tissue cultures have proved to be an excellent tool for investigating the cellular localization of the uptake of transmitter substances using autoradiography. The uptake of [3H]GABA and [3H]beta-alanine was studied in cultures of cerebellum, brain stem, spinal cord and dorsal root ganglia (DRG) of the rat. In c... | 517,268 | [
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Peripheral sensory stimulation and the release of transmitter amino acids in vivo from specific regions of cerebral cortex. | The effects of sensory stimulation on the release of amino acids from sensori-motor and visual cortices have been studied using a superfusion technique. Electrical stimulation of the brachial plexus contra-lateral to the superfusion cannula increased significantly the release of glutamate and glutamine from the sensori... | 517,270 | [
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GABA binding processes in rat brain and liver. | Although these studies have provided some further insight into GABA binding processes associated with transport and receptor-activation, such attempts remain limited due to the lack of specificity of the ligands used to displace these components. Thus, BMI appeared to interact with both transport and synaptic receptor ... | 517,277 | [
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An outbreak of infection caused by trimethoprim-resistant coliform bacilli in a geriatric unit. | An outbreak of infections, particularly of the urinary tract, caused by coliform bacilli resistant to trimethoprim, and originating in a geriatric unit, is described. The investigation of the outbreak and the analysis of factors predisposing to asymptomatic carriage of trimethoprim-resistant coliform bacilli enabled su... | 517,316 | [
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Myringotomy: a neglected office procedure. | An office myringotomy is an easily performed, underused procedure which has definite clinical applications. The family physician should become familiar with the technique, its indications and its complications. Indications include otitis media with concomitant meningitis, with matoiditis or with cranial nerve involveme... | 517,378 | [
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Inhalation toxicity studies with 1,3-butadiene -- 1. Atmosphere generation and control. | 1,3-butadiene, which is used extensively in the synthetic rubber industry, is a highly reactive, potentially explosive compound, presenting particular problems for the design and execution of inhalation toxicity studies. Before undertaking inhalation studies with butadiene, it was necessary to develop safe systems for ... | 517,437 | [
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Binding of concanavalin-A to critical-point-dried and freeze-dried human lymphocytes. | When human lymphocytes are treated with concanavalin-A (con A) and hemocyanin, the hemocyanin marker, which demonstrates con A binding sites, can be visualized by scanning (SEM) and transmission electron microscopy (TEM) on both critical-point-dried and freeze-dried cells. The ability to visualize the hemocyanin marker... | 517,445 | [
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0.028... |
Stability of refrigerated and frozen solutions of doxorubicin hydrochloride. | The stability of refrigerated and frozen solutions of doxorubicin hydrochloride was studied. Vials of doxorubicin hydrochloride with lactose (Adriamycin) were reconstituted with Sterile Water for Injection, USP, to provide a drug concentration of 2 mg/ml. Samples were refrigerated (4 C) for up to one year and frozen (-... | 517,541 | [
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Developing self-instructional learning materials--a case study. | A case study in the development of a self-instructional learning unit is presented. A seven-step systems approach "Design for Learning Programs" was followed in the development of a self-instructional unit on "The Direct Coombs' Test." Each step of the process as well as the problems encountered in producing a self-ins... | 517,560 | [
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Christ-Siemens-Touraine syndrome--a clinical and genetic analysis of a large Brazilian kindred: III. Carrier detection. | Detection of carriers of the Christ-Siemens-Touraine syndrome on the basis of data of physical examination has been possible in about 60--70% of the cases reported in 44 papers, including a large Brazilian kindred studied by the authors. Partial data, however, showed detection values ranging from 42% to 84%. | 517,572 | [
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Segregation of noisy Mendelian traits and the effect of age-dependence: a prolegomenon. | A discussion of the primordial confusion between the multiplicative Galtonian ("lognormal") trait and the imperfectly segregating Mendelian trait is laid out from a probabilistic standpoint. Several criteria used in comparing them (bimodality; bitangentiality; goodness of fit to the multinomialized form of the distribu... | 517,574 | [
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0.03828... |
Rapid assessment of fetal pulmonary maturity. | The absorbance of amniotic fluid at 653 nm has been measured in 300 specimens and found to have a significant correlation with the L/S ratio. Then 118 patients were further evaluated for neonatal outcome. RDS was absent in 99% of patients with mature absorbance values. This determination has the advantage of rapid perf... | 517,588 | [
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External ocular toxicity of dipivalyl epinephrine. | Of 26 patients enrolled in a study designed to assess the usefulness of dipivalyl epinephrine 0.1%, administered topically at 12-hour intervals, for lowering intraocular pressure in patients with glaucoma and ocular hypertension, six patients (23.1%) developed adverse external ocular side effects severe enough to requi... | 517,603 | [
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Calcium oxalate crystals in the aqueous. | We found octohedral crystals in the aqueous of a patient with phacolytic glaucoma. They were identified as calcium oxalate by their physical and chemical characteristics. | 517,605 | [
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Vasoactive intestinal polypeptide in vagally mediated pancreatic secretion of fluid and HCO3. | The role of nerves that liberate vasoactive intestinal polypeptide (VIP) in the porcine pancrease as mediators of the atropine-resistant action of the vagus on flow and bicarbonate (HCO3) secretion was examined. Efferent electrical stimulation of the vagus in atropinized pigs produced a profuse flow of pancreatic juice... | 517,650 | [
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Image latency and recall as functions of array size. | A comparison of image latencies and recall as a function of increasing arrays of objects involved three groups of subjects listening to descriptions of arrangements of objects and responding when they had visualized each array as a whole. After each latency response, one group of subjects indicated if they had visualiz... | 517,677 | [
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Some problems encountered in the psychoanalytic treatment of overt male homosexuality. | This article describes certain theoretical and clinical problems commonly met with during the psychoanalytic treatment of adult homosexual patients. Difficulties discussed are selected out of extensive clinical experience and are described under several headings: general problems, such as selection of patients, motivat... | 517,682 | [
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The therapeutic relationship in brief psychotherapy. | Brief psychotherapy is predicated upon a thorough knowledge of psychodynamics and careful conceptualization of each individual's psychopathology. Areas and methods of intervention must be concisely selected and clearly goal-related. As a modality, I see brief therapy relating to traditional therapy the way a short stor... | 517,686 | [
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Anti-acrosin antibodies in sera, colostrum and genital organs of vaccinated ewes: estimation and correlation with fertility. | Three ewes were vaccinated with boar sperm acrosin. Despite the presence of antiacrosin antibodies which crossreact with ram acrosin in the sera of the immunized sheep, no significant reduction in fertility was observed. Incubation of ejaculated or capacitated boar spermatozoa with anti-acrosin serum or IgG did not red... | 517,772 | [
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A rapid, sensitive method for quantifying enflurane in whole blood. | Thermal conductively detection (TCD) in conjunction with gas-liquid chromatography was employed for the analysis of enflurane in n-heptane extracts of whole blood. Enflurane was estimated to be 98 per cent extracted from whole blood by n-heptane. Analysis of enflurane standards ranging in concentration from 4.1 to 813 ... | 517,782 | [
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0.4389138,
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0.1522148,
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Biophysical and serologic comparison of four equine adenovirus isolates. | Four equine adenovirus isolates have been characterized with regard to their biophysical and serologic properties. Electron microscopic studies demonstrated that purified virions have a typical adenovirus morphologic characteristic, with 50-nm-long fiber projections at each vertex of an 80-nm-diameter icosahedron. Extr... | 517,826 | [
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-0.03875... |
The effect of increased ventilation on resistive load discrimination. | The ability of normal subjects to detect the addition of external resistive loads was determined both at rest and when ventilation was increased to more than 30 L/min by CO2 administration or exercise. Tidal volume, flow, and mouth and transpulmonary pressures were recorded during resistive load discrimination using st... | 517,855 | [
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0.00294... |
Postulated sources of Mycobacterium intracellulare and Mycobacterium scrofulaceum infection: isolation of mycobacteria from estuaries and ocean waters. | Mycobacteria biochemically and serologically similar to those isolated from humans have been found in estuaries and ocean waters in the south-eastern United States. This is consistent with the hypothesis that aerosols from these waters are one potential source of infection with these mycobacteria. | 517,862 | [
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0.1835275,
-0.0303142... |
Complete remissions in metastatic breast cancer treated with combination drug therapy. | One hundred sixteen patients with metastatic breast cancer who achieved complete remission with combination chemotherapy were analyzed to ascertain the factors that affect the duration of complete remission and the patterns of relapse. The median duration of complete remission was 17 months. Disease recurred in 81 pati... | 517,883 | [
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0.05400685,
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Guidelines for the care of patients hospitalized with viral hepatitis. | For years patients hospitalized with viral hepatitis have been placed in two categories of isolation--enteric precautions and blood precautions. This strategy was based on the inability to differentiate between hepatitis A and B and on the assumption that feces and blood from patients with either type might be infectiv... | 517,890 | [
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0.0836659,
0.10... |
The drug regulation process and the challenge of regulatory reform. | After 17 years of experience with the far-reaching 1962 amendments to the law regulating new drugs, a major effort is underway to overhaul the law. Important questions of health policy are involved. An extensive recent study by the Department of Health, Education, and Welfare's Review Panel on New Drug Regulation concl... | 517,893 | [
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0.2276139,
0.0108573,
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0.09... |
Traveling waves demonstrated by a revolving helix: a simple teaching aid. | A simple procedure for the demonstration of traveling waves in actual motion in the classroom is described. Using a matched set of experimental data on a) peak amplitude of basilar membrane oscillations, and b) phase-lag along the membrane, both for a given frequency of stimulation, it is possible to construct a solid ... | 517,919 | [
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0.4730784,
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-0.106... |
[Thyroid protein synthesis and insulin: influence of the hormone concentration (author's transl)]. | Canine thyroid slices were preincubated at 37 degrees C in the glucose-free TC 199 medium following in vitro addition of monocomponent insulin at increasing concentrations: from 10(-5) to 1 IU/ml. After 30 minutes, the incubation was continued in the presence of 3H-leucine (20 microCi/ml) for 1 h. The incorporation of ... | 518,026 | [
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0.001862113,
0.2211497,
0.4211099,
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... |
Ethnic diversity in Punjab as based on finger dermatoglyphics. | Four ethnic groups of Punjab having same dialect viz. Khatris, Jats, Brahmins and Muslims were taken to see ethnic differences in regards to the distribution of whorls, loops, and arches of finger dermatoglyphics. The results show that there is a great diversity in the four groups for these parameters. These groups wer... | 518,046 | [
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0.2213234,
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... |
In vitro activity of LY127935. | LY127935 is a unique new beta-lactam antibiotic. Its activity against 536 clinical isolates was studied by using microdilution methods of susceptibility testing and compared with the activities of cefamandole, cefoxitin, and cephalothin. The lowest concentrations required to inhibit at least 90% of strains tested (MIC(... | 518,080 | [
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0.1185071,
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0.3380403,
0.3195833,
0.02314566,
0.5228758,
... |
Vertical transmission of hepatitis B surface antigen in carrier mothers in two west London hospitals. | 126 children of 102 hepatitis B surface antigen (HBsAg) carrier mothers were delivered at Hammersmith Hospital and Queen Charlotte's Maternity Hospital, between 1971 and mid-1978. Blood tests on 110 of these children showed that 8 out of the 18 with Chinese mothers, but only 6 out of the 92 other children, have become ... | 518,104 | [
-0.1056596,
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0.02933161,
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0.1614476,
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Rectal aspirin--absorption and antipyretic effect. | Rectal acetylsalicylic acid was given to 14 children who had undergone open heart surgery. The effect on their temperatures was similar whether 15--30 or 30--50 mg/kg was given. Either dose was more effective than no treatment. The greatest fall in temperature occurred after 4 or 5 hours. Rectal aspirin in a triglyceri... | 518,111 | [
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0.4373153,
0.2724172,
0.122472,
-0.2863193,
0... |
Pulmonary alterations in rats exposed to 0.2 and 0.1 ppm ozone: a correlated morphological and biochemical study. | Weanling male Sprague-Dawley rats were fed either a synthetic diet supplemented with 11 mg vitamin E/kg body weight (to approximate average U.S. human dietary intake) or a commercial rat chow for 5 wk. At 2 months of age, rats were exposed to either 0.0, 0.1, or 0.2 ppm ozone continuously for 7 days. Morphological lesi... | 518,118 | [
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0.1512035,
0.6536831,
0.292779,
0.04487424,
0.5514054,
-0.04762421,... |
Chromosome aberrations induced by occupational exposure to mercury. | The incidence of chromosome aberrations was studied by peripheral blood incubation (52 hr, the last 4 hr in the presence of Colcemid) using a modification of the Evans' technique in twenty-two men exposed to either vapors of metallic mercury (Group I) or organic mercury (Group II). Mercury concentrations of the work ar... | 518,128 | [
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0.1820547,
0.2477647,
0.4490061,
-0.008809371,... |
Antagonistic effects of zinc and aluminum on lead inhibition of delta-aminolevulinic acid dehydratase. | In vitro and in vivo studies regarding the influence of metals on delta-aminolevulinic acid dehydratase activity in erythrocytes indicate that a lead concentration of 4 micrometer/l completely inhibits the enzyme. Zinc activates the enzyme both in vitro and in vivo at concentrations greater than 76 micrometer/l. Alumin... | 518,129 | [
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0.4513274,
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0.2049525,
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... |
Studies with clonidine (dixarit) in menopausal women. | Eleven women with menopausal symptoms were treated with 150 micrograms Clonidine (dixarit) daily. Before and during therapy, plasma estradiol-17 beta, LH, FSH and prolactin levels were measured by specific radio-immunoassays. In addition, each patient recorded the number of hot flushes a day and symptoms were monitored... | 518,136 | [
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... |
Hypercalcaemia in rheumatoid arthritis: investigation of its causes and implications. | When correction was made for hypoalbuminaemia, 23 of 50 ambulant patients with definite or classical rheumatoid arthritis were found to have hypercalcaemia. When these 23 patients were studied 6 months later, 7 had hypercalcaemia as defined by the correction factor for a low serum albumin level, and 6 of these patients... | 518,139 | [
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Perforated stress ulcer in infants: a silent threat. | Stress ulcer has become an important clinical entity and its two major complications--bleeding and perforation--are among the most baffling problems, in terms of management, in clinical practice. Perforation, though the less common of the two, is perhaps the most formidable particularly when this occurs in a very sick ... | 518,170 | [
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0.01656095,
0.2465961,
0.2105009,
0.3558282,
-0.05060051,
-0.1400787... |
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