title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Macromolecular secretion into various segments of the guinea pig epididymis. | The secretion of proteins of different segments of the guinea pig epididymis was studied using micropuncture and radiochemical techniques. Tissue and fluid samples were taken 24-48 hr after intraperitoneal injections of 2 mCi of tritiated lysine. Macromolecular secretion was higher in the caput than in the corpus and c... | 518,205 | [
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The amino acid sequence of the peptide moiety of the pseudomurein from Methanobacterium thermoautotrophicum. | The amino acid sequence of the peptide subunits of the peptide moiety of the sacculus polymer (pseudomurein) of Methanobacterium thermoautotrophicum was elucidated by analysing overlapping peptides obtained from partial acid hydrolsates of isolated sacculi. It is suggested that the peptide subunits are attached to gly... | 518,234 | [
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Capnocytophaga: new genus of gram-negative gliding bacteria. II. Morphology and ultrastructure. | Gram-negative, anaerobic gliding bacteria were isolated from normal supragingival plaque and from periodontal lesions. Isolates could be divided into two size classes: small 2.4-4.2 micrograms x 0.38-0.5 microgram and large 4.8-5.8 micrograms x 0.42-0.6 microgram cells. The outer membrane was either loose-fitting and w... | 518,235 | [
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Adenylate nucleotide levels and energy charge in Arthrobacter crystallopoietes during growth and starvation. | The adenylate nucleotide concentrations, based on internal water space, were determined in cells of Arthrobacter crystallopoietes during growth and starvation and the energy charge of the cells was calculated. The energy charge of spherical cells rose during the first 10 h of growth, then remained nearly constant for a... | 518,238 | [
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The psychiatrist shortage. What's the right number? | This report examines the assertion that there is a shortage of psychiatrists in the light of available methodologies for projecting the supply and demand for psychiatrists. We conclude that such projections are of little value and divert attention from other approaches to solving problems in mental health service deliv... | 518,243 | [
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Pain in patients with spinal cord injury. | For this study of intractable pain after spinal cord injury (SCI), a questionnaire was developed, pilot-tested and mailed to 356 previously hospitalized SCI patients, 200 (56%) of whom returned the completed questionnaire. Of the respondents, 160 (80%) reported abnormal sensation and 96 (48%) called the discomfort pain... | 518,270 | [
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[Epithelial neoplasms of the head and neck. Study of 72 cases treated with radiotherapy only or combined with chemotherapy]. | A comparison between the effects of radiotherapy with and without supplementary chemotherapy in 72 cases of head and neck tumours treated Turin, Oncology Department is reported. The overall results were similar to those in the international literature (59.7% local remissions 2 yr after treatment). Personal experience i... | 518,280 | [
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[Physiopathological and clinical features of hypernatremia]. | The observation of hypernatriaemia in a large series under a variety of clinical conditions (gastrointestinal loss, increased "forced loss", and insufficiency parenteral feeding) is made the occasional for an overview of its main physiopathological and clinical features. From the physiopathological standpoint, the synd... | 518,277 | [
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[Treatment of Hodgkin's disease: review of 90 cases]. | 90 patients suffering from Hodgkin's disease, 32 in stages I and II, 42 in stage III and 16 in stage IV have been studied retrospectively. The first were treated with supra and subdiaphragmatic extensive radiotherapy, the second with total nodal or polychemotherapy (MOPP), the third with polychemotherapy. Results were ... | 518,282 | [
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Vitamin A (retinol) status in the rat after a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin. | The effect of a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 10 microgram . kg-1, on the status of vitamin A (retinol) was studied in rats during an eight week period after administration. Retinol was determined spectrophotometrically after separation by means of high pressure liquid chromatography. ... | 518,291 | [
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Spread of infectious virus along the optic nerve into the retina in Borna disease virus-infected rabbits. | Selective damage of the optic nerve of 14 rabbits without interfering with the choroidal blood flow which supplies the retina and without altering the autonomic nerve supply was successfully achieved by Xenon coagulation. This procedure interrupted the axonal pathway between the brain and the eye. After experimental in... | 518,303 | [
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[Role of glycosaminoglycans in altering vascular wall permeability for atherogenic lipoproteins]. | The relationship between the pattern of distribution of lipoproteins and morphological features of atherosclerotic lesions was demonstrated by histoautoradiographic and histochemical methods in experiments using perfusion in vitro of aortas from atherosclerotic rabbits with atherogenic lipoproteins (LP) labeled in vari... | 518,366 | [
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Retinal fluorography using oral fluorescein. | Fluorescein sodium can be administered safely by mouth. The resulting fluorograms are useful in demonstrating many retinal conditions characterized by bright late leakage, such as cystoid macular edema. Oral administration of fluorescein may be preferred in studies of children, patients with difficult veins, and in som... | 518,385 | [
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Sino-orbital polyposis. | A 70-year-old woman with a long history of nasal and sinus polyps developed bilateral proptosis and left total external ophthalmoplegia. She was known to have hypercalcemia, which was later discovered to be caused by a parathyroid adenoma. X-ray studies, including computerized tomography, revealed increased radiodensit... | 518,388 | [
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Intraocular penetration of subconjunctivally administered 14C-fluorouracil in rabbits. | Fluorouracil is given for a variety of neoplasms by various administrative routes. Toxicity of susceptible normal tissue limits systemic dosage, but at this level intraocular tissue may not receive tumor-inhibiting concentrations. Subconjunctival administration of 6.25 mg of 14C-fluorouracil in 0.5-mL dosages resulted ... | 518,392 | [
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Reproductive performance of beef cattle in northwestern Queensland. | The reproductive performance of beef cattle in 5 herds mated all year round in north-west Queensland was examined from 1970 to 1973. Conception rates, conception patterns and branding rates were used to assess annual reproductive performance. The level of loss between the times of confirmed pregnancy and branding was d... | 518,419 | [
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Poisoning of chickens and ducks by pyrrolizidine alkaloids of Heliotropium europaeum. | The disease produced by feeding chickens and ducks a commercial poultry feed containing heliotrine and lasiocarpine, pyrrolizidine alkaloids of Heliotropium europaeum, is described. Illthrift, ascites and degenerative lesions in the liver were the major findings. Similar lesions occurred in chickens fed a diet containi... | 518,422 | [
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Similarity in the number of lifespan heartbeats among non-hibernating homeothermic animals. | An investigation was made of the available data on heart rates and maximum lifespan of a number of vertebrates from a variety of sources; only data pertinent to resting adult non-anesthesized homeothermic mammals and birds in a state of thermal neutrality were subsequently analyzed. All known hibernators were excluded ... | 518,447 | [
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Pilot performance during simulated approaches and landings made with various computer-generated visual glidepath indicators. | Two simulator experiments were conducted to quantify the effectiveness, in terms of pilot performance, of four different visual glidepath indicator systems (the 2-bar VASI, 3-bar VASI, T-VASIS, and PAPI) in the severely reduced nighttime visual environment often referred to as the "black hole." Performance in Experimen... | 518,455 | [
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Genetics and ontogeny of alcohol dehydrogenase isozymes in the mouse: evidence for a cis-acting regulator gene (Adt-i) controlling C2 isozyme expression in reproductive tissues and close linkage of Adh-3 and Adt-i on chromosome 3. | An electrophoretic variant previously reported for the stomach isozyme of alcohol dehydrogenase (ADH-C2) in inbred strains of Mus musculus (Holmes, 1977) has been used to localize the gene encoding this enzyme (Adh-3) on chromosome 3 near Va (varitint) (9.6 +/- 3.6% recombinants). Genetic variation of ADH-C2 activity i... | 518,534 | [
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Interaction of di-iodinated 125I-labelled alpha-bungarotoxin and reversible cholinergic ligands with intact synaptic acetylcholine receptors on isolated skeletal-muscle fibres from the rat. | 1. Intact synaptic acetylcholine receptors on freshly isolated rat skeletal-muscle fibres were characterized by their interaction with di-iodinated 125I-labelled alpha-bungarotoxin, acetylcholine and other cholinergic ligands at room temperature (22 deggrees C). 2. The time course and concentration dependence of 125I-l... | 518,540 | [
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Characterization of an oxygen-stable nitrogenase complex isolated from Azotobacter chroococcum. | In crude cell-free extracts of Azotobacter chroococcum, nitrogenase was much less sensitive to irreversible inactivation by O2 than was the purified enzyme. When nitrogenase was partially purified by anaerobic discontinuous sucrose-density-gradient centrifugation, O2-tolerance was retained. This preparation was conside... | 518,541 | [
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The binding of ferric iron by ferritin. | Equilibrium-dialysis experiments with 59Fe-labelled Fe(III) chelate solutions show that ferritin is capable of binding a limited number of Fe(III) atoms. Some of this Fe(III) is readily removed, but up to about 200 Fe(III) atoms/molecule remain bound after extensive washing. Some exchange of labelled Fe(III) with endog... | 518,550 | [
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Studies on the intracellular segregation of polyribosome-associated messenger ribonucleic acid species in the lactating guinea-pig mammary gland. | 1. Free and membrane-bound polyribosomes were isolated and the associated mRNA species characterized by cell-free protein synthesis, RNA-complexity analysis and polyribosome run-off in vitro. 2. Of the recovered polyribosomal RNA 85% was associated with membrane-bound polyribosomes and contained 87--93% of the total mi... | 518,553 | [
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Incorporation of N-fluoroacetyl-D-glucosamine into hyaluronate by rabbit tracheal explants in organ culture. | 1. Incubation of rabbit tracheal explants with N-[(3)H]acetyl-d-glucosamine and N-acetyl-d-[1-(14)C]glucosamine led to labelling of a number of soluble macromolecular products separable from the medium, after papain digestion, by ion-exchange chromatography. 2. With N-acetyl-d-[1-(14)C]glucosamine in the incubation med... | 518,560 | [
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Inhibition of gluconeogenesis in isolated rat liver cells by methylenecyclopropylpyruvate (ketohypoglycin). | 1. In isolated rat liver cells, hypoglycin is a less effective inhibitor of gluconeogenesis than its transamination product, methylenecyclopropylpyruvate (ketohypoglycin). 2. Methylenecyclopropylpyruvate at 0.3 mM inhibits gluconeogenesis from all substrates tested, except fructose. 3. Methylenecyclopropylpyruvate does... | 518,564 | [
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Casein turnover in rabbit mammary explants in organ culture. | 1. Explants of mammary gland from mid-pregnant rabbits were cultured in medium 199 containing insulin, prolactin and cortisol, and specific anti-casein immunoglobulin G was used to measure the amount, rate of synthesis and rate of degradation of casein in the explants in the presence of hormones and after removal of ho... | 518,567 | [
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N-formyl-L-methionine deformylase activity in human leucocytes and platelets. | Extracts of human neutrophils, lymphocytes and platelets enzymically deformylate N-formyl-L-methionine. Enzyme activity is stimulated by Co2+, inhibited by bivalent-cation chelators and unaffected by inhibitors of serine, thiol and carboxyl proteinases. Leucocyte or platelet N-formylmethionine deformylase may be import... | 518,571 | [
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... |
Atherogenesis in the White Carneau pigeon. Further studies of the role of carbon monoxide and dietary cholesterol. | Two experiments are described. In the first, 3 pairs of groups of 20 female White Carneau pigeons were fed on diets containing 0.5%, 1% or 2% cholesterol. Birds in one group from each pair were exposed to 150 ppm carbon monoxide (CO) for 6 h on 5 days of each week for 52 weeks, sufficient to raise their carboxyhaemoglo... | 518,746 | [
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0.09730873,
0.5782277,
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0.5184642,
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Lipoproteins and plasma cholesterol esterification in normal and diabetic subjects. | Serum lipoproteins, separated by preparative ultracentrifugation and the activity of the plasma enzyme lecithin: cholesterol acyltransferase (LCAT) have been measured in insulin-dependent diabetics, non-insulin-dependent diabetics and in age-matched non-diabetic controls. In the insulin-dependent diabetics, mean total ... | 518,747 | [
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0.2224523,
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0.1241696,
-0.111647... |
[Antibiotic resistance transmissible in "minor" Salmonella strains recently isolated in the Piedmont region]. | The presence of R factors in one hundred (100 strains of Salmonella, recently isolated in Piedmont Region, has been investigated. The resistance to 9 antibiotics has been determined for these strains. 83 proved resistant to one or more antibiotics and in particular 57 of these proved to be multiresistant. Only 18 R fac... | 518,755 | [
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0.1491295,
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... |
[Influence of composition of the culture media on the in vitro determination of the bacterial sensitivity to sulfonamides, trimethoprim and cotrimoxazole]. | The difficulties concerning the interpretation of results of susceptibility tests to sulphonamides, trimethoprim, co-trimoxazole have been investigated. The zones of inhibition produced by discs containing these drugs are peculiar since frequently they contain a light bacterial growth and small colonies. Therefore the ... | 518,756 | [
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0.6597629,
0.5000376,
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0.05513956,... |
[Changes in the bacterial flora of patients under antineoplastic treatment]. | The bacterial flora of the skin from different anatomical sites on cancer patients and a control group of medical personnel was examined. This was done to ascertain if antineoplastic therapy was able to change the pattern of microbial flora of patients and to provide a control for possible infectious complications. The... | 518,758 | [
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-0.03... |
[Effects of ionizing radiations on the ultrastructure of bursa of Fabricius]. | The alterations induced in the lymphoid and epitelial cells of the Bursa of Fabricius in chicks exposed at different doses of gamma rays mainly occur during the interfase. The extent of these alterations appears reduced in comparison with that observed in the chick thymus treated in the same way. | 518,763 | [
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0.3283139,
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0.1957811,
0.0762774... |
Chemical analysis of cryoglobulins observed in a case of essential IgG-IgA cryoglobulinaemia. | In a case of essential mixed (IgG-IgA) cryoglobulinaemia the carbohydrate and aminoacid composition of cryoglobulins was chemically analyzed. A normal aminoacid and sialic acid composition was observed, whereas the glucide percentage was augmented with respect to the normal range for the two classes of Ig. | 518,768 | [
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0.... |
Pericardial effusion complicating psittacosis infection. | A 13-year-old schoolboy developed a moderately large pericardial effusion during the course of infection with psittacosis. The value of echocardiography in differentiating between pericardial effusion and myocarditis is shown. | 518,785 | [
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0.3089899,
0.2744756,
-0.05503... |
Breath-by-breath halothane monitoring during anaesthesia. A study in children. | The use of a halothane meter in routine paediatric anaesthesia with controlled ventilation is described. The results demonstrate the accuracy achieved in the control of the alveolar halothane concentration. Measurement of the alveolar halothane concentration revealed responses to surgical stimulation otherwise obscured... | 518,797 | [
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0.305401,
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... |
Percutaneous cannulation of the dorsalis pedis artery. A prospective study. | Strain-gauge plethysmography was used to determine the systolic arterial pressure in the great toe of 38 patients (aged 23-70 yr) undergoing lung surgery. In eight patients (21%) manual compression of the dorsalis pedis artery reduced the arterial pressure in the great toe to less than 40 mm Hg, and cannulation of the ... | 518,804 | [
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0.08190823,
0.2328494,
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0.1202476,
0.5705273,
0.03922191,
0.0000093006... |
Cardiorespiratory effects of the sitting position in neurosurgery. | The cardiorespiratory effects of raising patients from the supine to the sitting position for neurosurgery were investigated. The change caused marked decreases in cardiac index, stroke volume, PaO2 and Qs/Qt, with a significant increase in (PAO2-PaO2) and total peripheral resistance. It is concluded that patients who ... | 518,805 | [
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0.1629507,
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0.2376081,... |
Intramembrane position of the fluorescent tryptophanyl residue in membrane-bound cytochrome b5. | We have developed a method to measure the intramembrane position of the fluorescent tryptophanyl residue in whole cytochrome b5 and the nonpolar membrane binding segment when these molecules are bound to phospholipid vesicles [Koppel, D.E., Fleming, P., & Strittmatter, P. (1979) Biochemistry (preceding paper in thi... | 518,849 | [
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0.154555,
0.06893367,
0.05717082,
... |
Effect of estrogen on ovalbumin gene expression in differentiated nontarget tissues. | By use of cloned DNA fragments as probes, low levels of ovalbumin RNA sequences (structural and intervening sequences) were detected in nuclear RNA extracts of nontarget tissues, such as liver, spleen, brain, and heart of chicks. The expression of the ovalbumin gene sequences was hormone dependent. In estrogen-stimulat... | 518,866 | [
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0.03356631,
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0.09170293,
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-... |
The biosynthesis of nitrogenase MoFe protein polypeptides in free-living cultures of Rhizobium japonicum. | The biosynthesis of the constituent polypeptides of nitrogenase component I (Rj 1) in free-living cultures of Rhizobium japonicum (strain 110) was investigated under different growth conditions. Cells were pulse-labelled and the proteins analysed by one and two-dimensional gel electrophoresis. The positions of the cons... | 518,887 | [
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0.1817451,
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Effect of even- and odd-numbered saturated fatty acids on glycerolipid synthesis in rat liver slices. | Effect of even- and odd-numbered saturated fatty acids, ranging from lauric to stearic acids, was studied on the de novo synthesis of glycerolipids in rat liver slices. For all fatty acids tested, a marked synthesis of saturated glycerolipids was observed except for phosphatidylethanolamine. When compared at the fixed ... | 518,892 | [
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Basis of thermostability in pig heart lactate dehydrogenase treated with O-methylisourea. | Acetamidination of pig heart lactate dehydrogenase (L-lactate:NAD+ oxidoreductase, EC 1.1.1.27) with ethyl acetimidate resulted in an increase of thermostability, and covalent bridge formation between pairs of lysine residues is observed. Guanidination with O-methylisourea of the enzyme also increases the thermostabili... | 518,917 | [
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0.5243421,
0.2563859,
0.198705,
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-0.0855... |
The primary structure of the asialo-carbohydrate units of the first glycosylation site of human plasma alpha 1-acid glycoprotein. | The elucidation of the structures of the carbohydrate units linked to glycosylation site I of human plasma alpha 1-acid glycoprotein is described. These carbohydrate units can be grouped into compounds with bi- (class A) and triantennary (class B) structures and the triantennary structure with a fucose residue (class B... | 518,919 | [
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... |
Interaction of alpha-actinin, filamin and tropomyosin with F-actin. | The abilities of alpha-actinin, filamin and tropomyosin to bind F-actin were examined by cosedimentation experiments. Results indicated that smooth muscle alpha-actinin and filamin can bind to actin filaments simultaneously with little evidence of competition. In contrast, tropomyosin exhibits marked competition with e... | 518,922 | [
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0.... |
[Electrogenesis of muscular fibers in the rat masseter muscle proper]. | It was established by the method of intracellular lead of membrane rest potentials (MRP) and action potentials (AP) that fibers with high MRP and little overshot are mainly located in superficial layers of the rat masseter muscle proper whereas those with low MRP and high overshot principally in deep layers. Excitabili... | 519,012 | [
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0.5524399,
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0.1318571,
... |
[Experimental studies of parmidin (pyridinolcarbamate) effect on microvascular permeability of the lungs, skin and mesentery]. | The effect of parmidin (pyridinolcarbamate) on microvascular permeability of several organs has been studied on experimental mice and rats using different models of increased vascular permeability, returned to normal by the drug due to its antibradykinine properties. The experimental results correlate with the clinical... | 519,015 | [
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... |
Influence of levamisole on the capacity of neutrophil granulocytes for ingestion and for the reduction of nitrobluetetrazolium. | With the aid of a modification of the NBT test it has been shown in in vitro and in vivo studies that levamisole does not affect the NBT reduction capacity of neutrophil granulocytes. The increased NBT positivity of these cells under the influence of levamisol is due to stimulation of ingestion. | 519,032 | [
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0.5279759,
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0.1984946,
... |
Effects of uptake inhibitors on responses of sheep coronary arteries to catecholamines and sympathetic nerve stimulation. | 1. Transmural stimulation of intrinsic sympathetic nerves and exogenous catecholamines produce beta 1-adrenoceptor mediated relaxant responses in strips of contracted sheep coronary artery. 2. The neuronal uptake inhibitors, metaraminol, cocaine and desipramine and the extraneuronal uptake inhibitor, cortisol, failed t... | 519,107 | [
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0.2208867,
0.2289888,
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-0.201012... |
Statistical errors in papers in the British Journal of Psychiatry. | In the 12 months from July 1977 to June 1978, out of 168 papers in the British Journal of Psychiatry, 139 (83 per cent) presented numerical results. A total of 63 papers contained statistical errors and at least one drew unsupportable conclusions. In many cases the errors were not considered to be severe, but they were... | 519,116 | [
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0.2447914,
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0.1570588,
0.06372026,
... |
Schneider's First Rank Symptoms: their prevalence and diagnostic implications in an Asian population. | In an in-patient population in Sri Lanka, only those receiving a diagnosis of schizophrenia had Schneider's First Rank Symptoms. Amond 65 males and 104 females, the prevalence of FRS was 25.4 per cent. Those patients with FRS in the first episode are likely to develop more during subsequent episodes. An attempt is made... | 519,118 | [
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0.1041558,
0.2059101,
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0.... |
The structure of delinquent values: a repertory grid investigation. | Two experiments are reported, employing repertory grid technique and designed to test predictions derived from Matza & Sykes' (1961) account of the relationship between delinquent and conventional values. These predictions were confirmed. In addition, following the demonstration of equivalence in the structure and ... | 519,137 | [
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0.06672455,
0.1206387,
0... |
Mental imagery, human memory, and the effects of closed head injury. | Several recent experiments suggest that mental imagery is relevant to an explanation of memory impairment resulting from neurological damage. This study compared a group of patients with recent closed head injuries with a control group of orthopaedic patients in their recall of concrete and abstract words. The head-inj... | 519,141 | [
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0.116004,
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0... |
Leucocyte counts in the diagnosis and prognosis of acute appendicitis in children. | Preoperative total and differential leucocyte counts were made in 225 children with acute appendicitis, 50 children with a normal appendix and 100 children with acute abdominal pain which resolved without any therapy. When adjusted to age, neutrophilia in 96 per cent, 30 per cent and 32 per cent and leucocytosis in 41.... | 519,164 | [
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0.1777821,
-0.2050732,
0.04832212,
0.2391309,
-0.04518128,
-0.174780... |
Postoperative hypoxaemia: oesophagectomy with gastric replacement. | Pre- and postoperative arterial blood samples were analysed for oxygen partial pressure (PaO2) and carbon dioxide partial pressure (PaCO2) in a consecutive series of 21 patients subjected to two- or three-stage oesophagectomy for carcinoma of the oesophagus. The forced vital capacity (FVC) was measured at the same time... | 519,170 | [
-0.2256888,
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0.01735221,
0.1714552,
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0.14328,
0.1170935,
0.0... |
Fibreoptic injection of oesophageal varices. | A new technique for injecting sclerosant into oesophageal varices uses a flexible gastroscope. Once the gastroscope has been inserted a flexible tube with a window cut into its distal end is pushed down over the gastroscope until a varix protrudes through the window. The varix can then be injected with a needle passed ... | 519,186 | [
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0.07707479,
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0.2028216,
0.128683,
-0.03395095,
0.... |
Haemorrheological response to plasma exchange in Raynaud's syndrome. | Eight patients with Raynaud's syndrome were treated by weekly plasma exchange for four weeks using a Haemonetics Model 30 Blood Processor. The mean whole-blood viscosity at a shear rate of 0.77/s was significantly lower after treatment, and the mean index of red-cell deformability was significantly improved. In four pa... | 519,354 | [
-0.2394518,
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-0.07697014,
0.2858485,
0.04622019,
0.0280263... |
Long-term survival of patients with breast cancer: a study of the curability of the disease. | A retrospective analysis was made of 3878 cases of breast carcinoma first seen in Edinburgh from 1954 to 1964. During this time there was a policy to treat breast cancer by simple mastectomy and x-ray therapy, and over 90% of cases classified as international stages I and II were so treated. The mortality in these wome... | 519,399 | [
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0.08732775,
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0.3328713,
0.3695192,
-0.07226197,
... |
Muscarinic receptors in the central nervous system of the rat. II. Distribution of binding of [3H]propylbenzilylcholine mustard in the midbrain and hindbrain. | The distribution of muscarinic receptors has been studied in the rat midbrain and hindbrain by counting silver grains in light microscope autoradiographs of the specific (atropine-sensitive) binding of [3H]propylbenzilylcholine mustard in cryostat sections. Of the 78 areas studied 6 had grain counts between 6 and 9 tim... | 519,515 | [
0.2881164,
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0.196437,
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0.2347777,
0.4050875,
0.09932401,
... |
Modes of rouleaux formation of human red blood cells in polyvinylpyrrolidone and dextran solutions. | The mechanics by which normal human erythrocytes join on a plastic cover slip into two cell doublets and larger aggregates of rouleaux were studied microscopically. Polyvinylpyrrolidone (PVP-360) or dextran (DX-70 or DX-110) were used as the rouleau agents. The minimum concentration of the rouleau-inducing agents requi... | 519,523 | [
0.1041022,
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0.09119571,
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0.03726412,
0.1974681,
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-0.0820956,... |
Amino acids and the synaptic pharmacology of granule cells in the dentate gyrus of the rat. | Granule cells in the dentate gyrus in the hippocampi of anaesthetized rats were excited by stimulation of the contralateral hippocampus (the commissural input) and the ipsilateral entorhinal cortex (the perforant path). The cells were also activated by the electrophoretic administration of various amino acids. A select... | 519,538 | [
-0.1016054,
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0.3021018,
0.3356138,
0.2183341,
0.0... |
[Renal and perinephritic abscesses in children]. | One child with a pure perinephric abscess and three with renal abscesses, one of which had perinephric extension, are described. All presented with a long course of subacute infection leading to localizing symptoms or signs in the flank. The diagnosis was confirmed by radiologic examination. All the abscesses were surg... | 519,594 | [
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0.16674,
0.029555,
0.02139057,
0.3377571,
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-0.048111... |
Successful management of quadruplet pregnancy in a perinatal unit. | A case of quadruplet pregnancy is outlined and the management is described to demonstrate the application of monitoring and therapeutic procedures currently available for a multifetal pregnancy. Recording of the nonstressed fetal heart rate, ultrasound monitoring and glucocorticoid stimulation of pulmonary biochemical ... | 519,612 | [
-0.22055,
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0.1557767,
0.05517843,
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0... |
A review of Providencia bacteremia in a general hospital, with a comment on patterns of antimicrobial sensitivity and use. | Six cases of Providencia bacteremia occurring between 1969 and 1978 were reviewed. These cases represented 3% of the gram-negative bacteremias occurring at one hospital. All six cases of Providencia bacteremia were secondary to urinary tract infection with P. stuartii, and in most the infection developed only shortly b... | 519,613 | [
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0.002661916,
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0.06307153,
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0.2714644,
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0.1850464,
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0.1883856,
-0.04040349,
0.1468373,... |
Psychiatric implications of the mitral valve prolapse syndrome (MVPS). | The mitral valve prolapse syndrome (MVPS) is an infrequent outcome of mitral valve prolapse, a common and usually benign structural abnormality. Psychiatric patients often present with symptoms indistinguishable from MVPS, knowledge of which is thus essential for differential diagnosis. Even when prolapse of the mitral... | 519,642 | [
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0.1060017,
0.2148351,
0.1577977,
-0.0466045,
0.0... |
Spontaneous intermittent reversal of blood flow in intrahepatic portal vein branches in cirrhosis of the liver. | The intrahepatic portal venous flow in cirrhosis of the liver was evaluated by percutaneous transhepatic portography and hepatic arteriography. Spontaneous reversal of flow in segmental portal vein branches was documented. Changes in hepatic arterial inflow and portal venous pressure may result in intermittent changes ... | 519,674 | [
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-0.06101175,
0.1316252,... |
Particle-induced erythropoietin-independent effects of erythroid precursor cells in murine bone marrow. | A possible regulatory action of phagocytic cells on erythropoiesis was investigated by infusion of inert polystyrene latex particles (LAT). LAT appeared to induce changes in the femoral content of erythroid progenitor cells. These changes were most pronounced in primitive erythroid progenitor cells (BFUe) and appeared ... | 519,701 | [
0.1097316,
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0.5107825,
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0.1892698,
... |
Cytochemistry and freeze-fracture of membranes isolated from the electrocyte of Electrophorus electricus (L.). | Membranes were isolated from the main electric organ of Electrophorus electricus and studied by means of cytochemistry and freeze-fracture. The membrane fractions consisted of vesicles inside-in as determined by localization of anionic sites using colloidal iron and cationized ferritin particles. The anionic sites were... | 519,706 | [
-0.2707746,
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0.2555009,
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0.1055504,
0.2527747,
-0.29827... |
The culture of tissue from the ovary of the goldfish Carassius auratus. | Small pieces of ovarian tissue derived from immature goldfish have been maintained in culture periods of up to three months. The progress of the culture was monitored by light and electron microscopy and showed that although degenerative changes occurred in the large oocytes the small oocytes and oogonia survived for t... | 519,709 | [
0.2585975,
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0.2805081,
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0.2486293,
0.3815597,
0.1187141,
-0.05584318,
0.... |
Seasonal changes in the reproductive system of the female white-crowned sparrow, Zonotrichia leucophrys gambelii, in captivity and in the field. 2. The incubation patch. | The ventral apterium of free-living female White-crowned Sparrows (Zonotrichia leucophrys gambelii) becomes an incubation patch during the breeding season. At this time, it loses its feathers, increases in wet and defatted dry weight, and undergoes marked histological alterations. At times of year other than the breedi... | 519,711 | [
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0.1875098,
0.3202557,
-0.21661... |
Fine structure of sensory tubes on the antennule of Conchoecia spinirostris (Ostracoda, Crustacea). A new type of sensillum in crustaceans. | In addition to setae, the first antennae of Conchoecia spinirostris also bear soft sensory tubes (female: 4 tubes + 1 seta; male: 2 tubes + 3 setae). These tubes were examined electron microscopically. Each tube is divided into 4 regions: the stem, the bulbous region, the main region, and the tip. A tube contains 40--6... | 519,714 | [
0.1939078,
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0... |
The fine structure of ventral prostatic secretory epithelial cells in older rats. | The ventral prostatic secretory epithelial cells in older rats were studied by light and electron microscopy. The cells vary in height in different parts of the same organ, and ultrastructurally they show the presence of a developed secretory apparatus such as well-developed Golgi body and abundant rough endoplasmic re... | 519,717 | [
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0.5080782,
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0.2555958,
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Effects of stimulation and rest on the ultrastructure of the excitatory neuromuscular junctions of Locusta migratoria L. | The terminals of the fast axon on extensor tibiae muscle fibres of Locusta were examined in untreated nerve-muscle preparations and in preparations stimulated electrically at frequencies varying from 0.5 to 100 Hz. The ultrastructure of the terminals in preparations stimulated at the lower range of these frequencies, w... | 519,727 | [
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0... |
Ultrastructural development of the neurohemal organ joined to the ecdysial gland after imaginal moulting in the male isopod Sphaeroma serratum Fab. (Crustacea Flabellifera). | The present ultrastructural study deals with the lateral cephalic nerve plexus of Sphaeroma serratum, a neurohemal organ joined to the Y organ (ecdysial gland). This plexus acts as a storage centre for neurosecretory products from two sources: the two autochtonous cells (plexus cells) within the plexus itself, and the ... | 519,731 | [
-0.452212,
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0.1346053,
-... |
Separation of RNA transcription and processing activities from X. laevis germinal vesicles. | A procedure suitable for en masse preparation of germinal vesicles (GV) from X.laevis oocytes (Scalenghe et al., 1978) has been adapted for studies of transcription. Extracts from GV contain activities for transcription of tRNA genes and for processing the transcription product. The two activities have been separated b... | 519,751 | [
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0.632901,
0.07321481,
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... |
Nonallelic histone gene clusters of individual sea urchins (Lytechinus pictus): mapping of homologies in coding and spacer DNA. | The linear arrangement and lengths of the spacers and coding regions in the two nonallelic histone gene variant clusters of L. pictus are remarkably homologous by R loop analysis and are similar in general topography to the histone gene repeat units of other sea urchins examined to date. No interventing sequences were ... | 519,758 | [
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0.3889562,
0.06796189,
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The complete sequence of a chromosomal mouse alpha--globin gene reveals elements conserved throughout vertebrate evolution. | The mammalian alpha- and beta--globin genes are thought to have evolved from a common ancestral sequence by a duplication event that occurred over 500 million years ago. We have now determined the entire nucleotide sequence of a cloned mouse alpha--globin gene, including regions that flank and interrupt the coding sequ... | 519,760 | [
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-... |
The linkage arrangement of four rabbit beta-like globin genes. | Four different regions of rabbit beta-like globin gene sequences designated beta 1, beta 2, beta 3 and beta 4 were identified in a set of clones isolated from a bacteriophage lambda library of chromosomal DNA fragments (Maniatis et al., 1978). Restriction mapping and blot hybridization (Southern, 1975) studies indicate... | 519,768 | [
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0.4013574,
0.1706533,
-0.1967987,
... |
Assay of erythrocyte glucose-6-phosphate dehydrogenase on the GEMSAEC analyser. | A procedure for the assay of glucose-6-phosphate dehydrogenase (EC 1.1.1.49) in erythrocytes on the GEMSAEC centrifugal analyzer using a modification of Beutler's procedure is described. Glucose-6-phosphate dehydrogenase activity is corrected for the contributing activity of 6-phosphogluconate dehydrogenase (EC 1.1.1.4... | 519,850 | [
0.2043918,
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0.2730352,
0.597268,
0.2148108,
0.308241,
0.0848... |
Modification of the normal postural changes in plasma renin activity by the application of positive pressure to the legs. | In six normal male subjects plasma renin activity (PRA) rose progressively on standing over a 2 hour period. PRA fell to basal levels after a further 2 hours of recumbency. The rate of rise of PRA on standing was largely abolised following the application of an anti-gravity ('G') suit. Continuous monitoring of blood pr... | 519,867 | [
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0.0754469,
0.01695862,
0.0908877,
-0.2482716,
-0.07015128,
0.03694... |
Inheritance of microtia and aural atresia in a family with five affected members. | Only a few reports of congenital meatal atresia and microtia have been published. Dominant as well as recessive inheritance has been suggested. We report a family with five affected members in two generations. An irregularly dominant transmission seems to be the most likely explanation. | 519,905 | [
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0.08107077,
... |
Properties of inactive renin in human plasma. | 1. "Inactive" renin in human plasma can be revealed by pH 3.3- or cold-mediated activation and in normal plasma represented 76% of the "total" renin. 2. Pregnancy plasma contained considerably more "inactive" renin and consisted of 93% of "total" renin. 3. "Active" renin in normal plasma had an apparent molecular weigh... | 519,909 | [
-0.1024172,
0.2638682,
-0.4886183,
0.268059,
0.1744545,
-0.2228258,
-0.1198883,
0.1684765,
0.4815589,
0.2125203,
-0.003369954,
0.1127895,
0.1227044,
-0.2696969,
-0.1011489,
-0.04105342,
-0.3577437,
0.1496226,
0.3946239,
-0.002050017,
-0.007315482,
0.268204,
-0.2975819,
... |
Clonidine and sympathetic activity during sleep. | 1. Blood pressure, heart rate, plasma noradrenaline and electroencephalographic variables were measured simultaneously during sleep in five healthy males before and after slow-release clonidine (300 micrograms orally) or placebo. 2. The blood pressure fall during sleep correlated significantly with the depth of sleep. ... | 519,960 | [
-0.07926307,
0.2525408,
-0.5823688,
-0.320046,
0.09831246,
-0.4612558,
-0.3638765,
-0.05341147,
-0.01456762,
-0.1474783,
-0.008194365,
0.1609215,
0.154588,
0.1250846,
-0.4296793,
-0.1500221,
-0.4181505,
-0.009086933,
-0.06563728,
0.02547901,
-0.056701,
-0.03750099,
0.0400... |
Orbital trauma evaluation by computed tomography. | Computed tomographic scans are useful for the evaluation of orbital trauma because they provide visualization of fractures, soft tissue damage, and embedded foreign bodies. Six cases are presented to demonstrate the usefulness of these studies in the evaluation of patients with a variety of injuries. By using both coro... | 519,979 | [
-0.2607514,
0.1573967,
-0.005578207,
-0.291089,
-0.1119363,
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-0.2352288,
-0.1870069,
0.1486623,
0.04972142,
0.1732268,
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-0.356816,
-0.1189631,
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-0.2029229,
0.2464001,
0.07329658,
0.1342196,
0.1105067,
0.1461385,
-0.04370511,
... |
Long-term survival of subacute cardiac rupture with tamponade in acute myocardial infarction, without surgical intervention (the role of pericardiocentesis). | Four patients are described with cardiac tamponade caused by subacute cardiac rupture in acute myocardial infarction with long-term survival of two of them. Three patients were treated by pericardiocentesis. Clinical signs and symptoms and diagnostic problems are discussed stressing the need for a well-trained team of ... | 519,997 | [
-0.2230856,
0.09651208,
-0.1523824,
-0.3470587,
0.009822547,
-0.2438041,
-0.01167991,
-0.3375632,
-0.07578792,
-0.02686136,
0.1743544,
0.04040456,
-0.1443755,
-0.02725508,
-0.08071117,
-0.1845725,
-0.3139444,
-0.0003961292,
-0.1076865,
0.2401852,
0.3013739,
0.1233844,
-0.... |
An explication of 'wind illness' in northern Thailand. | 'Wind illness' is a very common complaint among the Northern Thai, yet is rarely recognized by Thai physicians trained in biomedicine. Persons most susceptible to 'wind illness' are adult women who have ever borne a child. Consequently, data were obtained from 415 everparous women, 43% of whom reported ever having had ... | 520,020 | [
-0.1183541,
-0.009093454,
0.2466812,
-0.04336857,
-0.02252226,
-0.09035207,
-0.5296909,
-0.0884827,
0.147411,
-0.03771609,
0.05310354,
0.2084811,
-0.1657026,
0.1953398,
-0.09613619,
-0.01853852,
-0.1872978,
0.2084625,
-0.4930763,
-0.3143807,
-0.1707874,
0.4279924,
-0.2992... |
Folk concepts of mental disorder among the Lao: continuities with similar concepts in other cultures and in psychiatry. | Folk concepts for mental disorder were studied among rural Lao people. While predominatly inferring etiology (e.g. spirit-caused disorder), certain terms also emphasized particular descriptive psychopathology or behavioral abnormality. Preventive strategies were stressed for insanity due to "excessive worry' or "broken... | 520,021 | [
0.009573377,
0.07421001,
0.215429,
0.03208176,
0.126965,
0.004071435,
-0.2010573,
-0.2368608,
-0.08663522,
-0.1318998,
0.1323378,
0.1750251,
-0.04816002,
0.2943967,
-0.1828031,
0.2823305,
-0.6763073,
0.3299566,
0.08370605,
-0.407387,
0.06675171,
0.3569331,
-0.3026534,
-... |
Evaluation of electrofulguration in control of bleeding of experimental gastric ulcers. | The safety and efficacy of electrofulguration for control of bleeding from standard canine experimental gastric ulcers was studied. At settings of 2, 5, and 8 on a Valleylab SSE-3 generator, 0.5-sec applications provided effective hemostasis. However, a setting of 2 required an excessive number of applications. Setting... | 520,104 | [
0.1318204,
0.2429882,
-0.3005305,
-0.4734393,
-0.09199864,
-0.1954614,
-0.07034017,
-0.1535179,
-0.03340152,
-0.04338023,
-0.1316694,
-0.02841462,
-0.1736629,
-0.4333761,
-0.317747,
0.04782281,
0.1599093,
-0.1638298,
0.1839008,
-0.04236931,
0.3905343,
-0.08322456,
-0.0725... |
Congenital hepatic fibrosis (asymptomatic and latent form) and multiple gastric ulcers. | Congenital hepatic fibrosis (asymptomatic and latent form) was diagnosed in a 67-year-old male during laparotomy for a gastric ulcer. The gastrectomy specimen revealed multiple chronic ulcers with healing in the form of villous mucosal hyperplasia. The pathological diagnosis of congenital hepatic fibrosis and similar h... | 520,111 | [
-0.1971892,
-0.07630993,
-0.1559081,
-0.246052,
0.3555459,
-0.1852031,
-0.1925298,
-0.2785805,
0.1582139,
0.3027889,
0.4096209,
0.08480091,
-0.3068197,
-0.1256323,
-0.3225094,
-0.01419306,
-0.4508625,
0.04973269,
0.1776748,
-0.2484616,
-0.006742766,
-0.05530887,
-0.231019... |
[Effect of dihydroergotamine on pulmonary perfusion in acceleration stress (author's transl)]. | An orthostatic circulatory load of varying degree (1-4 G) can be simulated by means of a human centrifuge. This results in a partial shifting of the intrathoracic blood volume into the capacity vessels of the lower extremity. In the pulmonary region, this is associated with a decrease in perfusion from the apical to th... | 520,155 | [
-0.2056428,
0.08964107,
-0.5692521,
0.009756949,
0.1433999,
-0.08734468,
-0.149852,
-0.2823738,
-0.09380295,
-0.3325518,
-0.3048635,
0.006262832,
0.1242969,
-0.008197978,
-0.7755657,
-0.04445106,
-0.03241676,
-0.09171293,
-0.06981291,
0.4274883,
0.2863841,
0.04577114,
0.1... |
[Sulprostone, a new prostaglandin E2 derivative (author's transl)]. | Sulprostone, a new synthetic prostaglandin E2 derivative, was used for interruption of pregnancy in 479 patients with different lengths of pregnancy. Systemic forms of administration (i.v. and i.m.) were superior to non-systemic ones (intraamnial, extraamnial). In comparison with prostaglandins used up to now this subs... | 520,164 | [
-0.2250632,
0.2762514,
-0.05547971,
-0.1414122,
0.2080142,
-0.08905853,
-0.2156636,
-0.04843793,
0.3484269,
0.04678699,
-0.1019152,
0.1816275,
0.3139616,
0.03599267,
-0.2865177,
-0.3399151,
-0.6655307,
-0.04942752,
0.05637579,
0.1333539,
0.08961146,
0.2371862,
-0.1058284,... |
[Paget's osteodystrophia deformans. Occurrence, clinical aspects and complications]. | 33 monostotic and 27 polyostotic manifestations were found in 60 patients with Paget's disease of bone, 30 of whom were females (mean age 65.7 years) and 30 males (mean age 62.8 years). Pelvis, right tibia, lumbar spine, skull and sacrum were most commonly affected. Alkaline phosphatase activity in serum was raised in ... | 520,181 | [
0.01102635,
-0.01445235,
0.1911557,
-0.1076159,
-0.02464961,
-0.5526356,
-0.1869368,
-0.07628498,
0.04061744,
0.03441388,
0.122193,
-0.1158026,
0.1746569,
-0.09962369,
-0.3840823,
-0.06588703,
-0.3436631,
0.1247535,
0.03448768,
0.1204113,
0.3623167,
0.1846951,
-0.1392514,... |
[The influence of food-supply to the concentration of blood ammonia (author's transl)]. | It has been determined of 70 liver-healthy probands the ammonia concentration of capillary blood after poor on protein respectively rich on proteine food in 30 minutes distances. It comes in both groups to a spontaneous ascent the concentration of ammonia. The highest ammonia concentration depends on the content of pro... | 520,270 | [
-0.09399801,
-0.3456638,
-0.03198946,
0.1580771,
0.2951171,
-0.2607453,
-0.1793572,
0.03775954,
-0.1288046,
-0.2118319,
0.2643369,
0.281408,
-0.02445568,
-0.09713734,
-0.7836741,
-0.3440923,
-0.292707,
0.1025626,
-0.3718222,
0.1738586,
0.06198491,
0.165139,
-0.001358926,
... |
A sensitive, convenient radioimmunoassay procedure which demonstrates that serum hTSH is suppressed below the normal range in thyrotoxic patients. | A highly sensitive radioimmunoassay procedures for the measurement of serum hTSH is described which permits delineation of the entire range of values in normal subjects (0.5-4.5 microU/ml). The procedure involves the concentration of hTSH from serum by adsorption to concanavalin A covalently bound to 4B Sepharose, Lact... | 520,279 | [
-0.04994674,
-0.3134597,
0.1102322,
0.06192704,
-0.0128611,
-0.2484879,
-0.2750062,
0.2665839,
0.0466122,
0.07638354,
0.3007401,
0.03815528,
-0.03166793,
0.161224,
-0.1990499,
-0.1303055,
-0.4443593,
0.03760545,
0.01181527,
0.0791929,
0.2293038,
0.217434,
-0.05893232,
-... |
Glycosulphatase from Pseudomonas carrageenovora. Purification and some properties. | A glycosulphatase present in the soluble fraction of disrupted Pseudomonas carrageenovora has been purified 500-fold by gel filtration on Sephacryl S-200 and ion-exchange chromatography on DEAE-Sepharose CL-6B. By dodecylsulphate/polyacrylamide gel electrophoresis the enzyme is practically homogeneous and has a molecul... | 520,310 | [
0.0884275,
0.09021937,
-0.06754938,
0.1197696,
-0.2533085,
-0.1378359,
-0.05165828,
0.05972131,
-0.004674484,
-0.1121001,
-0.03471118,
0.04306263,
-0.3288098,
-0.1854461,
-0.1710294,
0.1082717,
-0.07061075,
0.3215738,
0.2019754,
0.1784257,
0.2722261,
0.157218,
-0.2592428,... |
Differences in the interactions of liver alcohol dehydrogenases with probes binding into the substrate pocket. | The interactions of three groups of probes (berberine alkaloids, tricyclic psychopharmaca and acridine derivatives) with isoenzymes of horse liver alcohol dehydrogenase and with rat liver alcohol dehydrogenase have been examined. These compounds inhibit the activity of the EE isoenzyme of horse liver alcohol dehydrogen... | 520,311 | [
-0.1160187,
0.2398292,
-0.5478614,
0.103292,
-0.1551383,
0.07137565,
-0.2220621,
-0.09369154,
0.09955934,
-0.06683298,
-0.08046296,
-0.3063878,
0.1983572,
0.4763492,
-0.3708559,
0.2336735,
-0.9612122,
0.01560621,
0.2669935,
0.2879134,
-0.04812073,
0.1843873,
-0.08489048,
... |
Genes and mRNAs coding for zein polypeptides in Zea mays. | Zein messenger RNAs from maize endosperm were purified by successive oligo(dT)-cellulose chromatography and sucrose gradient centrifugation. Polyacrylamide gel electrophoresis under denaturing conditions revealed the presence of two size classes of zein messenger RNAs of Mr 3.5 x 10(5) and 4.10 x 10(5). The mRNA was sh... | 520,323 | [
0.1135357,
0.04433859,
0.0002034984,
0.02408373,
0.3173668,
-0.2094838,
-0.1795401,
-0.06506134,
0.4307135,
0.2931236,
0.1449907,
-0.1937399,
0.1176222,
0.1719251,
-0.542231,
-0.05528061,
0.1323801,
0.07060458,
0.1492608,
0.09602559,
0.6145861,
0.3074701,
-0.2413383,
-0... |
A morphometric analysis of microtubules in relation to the inhibition of lysosome movement caused by colchicine. | Colchicine was administered intraperitoneally to rats in doses which are known to inhibit the basal migration of lysosomes in uterine epithelial cells. The fractional volume of microtubules in the cells was then measured by morphometry. Colchicine at 0.10 mg/kg reduced the microtubule content of the cells from 0.22% do... | 520,337 | [
0.2228833,
0.2305689,
-0.4091568,
0.2227616,
0.1617874,
-0.1622774,
0.3135484,
-0.01714375,
0.2438152,
0.1687904,
-0.1768266,
-0.05506676,
-0.1370855,
0.2393933,
-0.248493,
0.2380823,
-0.558426,
0.3387466,
0.1713234,
0.2130912,
0.2761395,
0.4266013,
0.1529036,
0.2345652... |
The application of radioactive labeled leucocytes for the proof of inflammations. | The methods we have tested are reliable for the labeling of granulocytes and monocytes as well as with colloidal substances and with soluble 99mTc-phytate. Supravital colorations and electronmicroscopic pictures do not show any damage of the cells caused by the labeling procedures. In the clinical application after the... | 520,344 | [
-0.003070271,
0.1780096,
-0.1937717,
0.1048619,
-0.04818258,
-0.1182821,
-0.1783588,
0.1160884,
0.1088979,
-0.0464426,
0.02421815,
-0.3699352,
-0.04803867,
0.1023548,
-0.7366509,
-0.1566439,
-0.03020166,
0.0282574,
-0.01122255,
0.4658058,
0.05724712,
0.243975,
-0.04491246... |
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