title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Major surgery in patients with chronic renal failure. | To determine the risks of performing major surgical procedures on patients with chronic renal failure, the charts of twenty-nine hemodialysis patients who underwent thirty-eight elective and nine emergency operations were reviewed. Preoperative preparation included adequate hemodialysis of the patients, 88 per cent of ... | 596,544 | [
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The asymptomatic bruit. | A review of 144 carotid endarterectomies performed in 108 patients at the Oklahoma Health Science Center over the past six years showed an acceptable operative morbidity and mortality in group of patients with an asymptomatic midcervical bruit who underwent prophylactic carotid endarterectomy prior to anticipated elect... | 596,551 | [
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[Intraoperative autotransfusion and haemolysis (author's transl)]. | In 29 patients (12 vascular and 17 trauma cases) receiving autotransfusion the effects of haemolysis caused by the Bentley ATS-system were examined. The following parameters were monitored: 1. Overall haemolysis rate and fractions in serum and urine, --2. Total and direct bilirubin in all patients with or without preex... | 596,608 | [
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Body fluid compartments. | The terms mole, molality, molarity, osmole, osmolality, osmolarity, osmolar gap and anion gap are defined and their clinical usefulness indicated. The following body fluid compartments are described: total body water (TBW), extracellular fluid (ECF), intracellular fluid (ICF), transcellular fluid TCF), plasma volume, r... | 596,611 | [
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Intra-operative fluid and electrolyte requirements. | The intravenous administration of Hartmann's solution at a rate sufficient to maintain the hourly urine volume between 0.5 and 1.0 ml/kg/hr is recommended during major operations. Intra-operative extracellular volume expansion followed by the administration of sodium containing fluids for 48 hours postoperatively decre... | 596,615 | [
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A versatile computing system for sampling, manipulation and display of biological signals using high-level language. | A medium sized minicomputer system is presented as an attractive way of balancing the cost of computing equipment with that of programme development. A versatile circuit has been coupled to a computer system and programmes have been developed to control the functions of this circuit. With such a system it is possible f... | 596,620 | [
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[Low frequency vibration on human hollow bone (author's transl)]. | With the aid of a stable fixation and a hammer system was removed the bone in vibrations which was registered. The vibrations have relations to the regions of the bone and have a practical connexion to the knowledge of the fracturation of the bone. | 596,646 | [
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Neonatal muscle: an electron microscopic study. | A spaced serial section, electron microscopic study of the extensor digitorum longus of the 2-day-old rat was undertaken to determine whether all cells wedged between the basement membrane and the sarcolemma of a muscle fiber, regardless of their morphology, were true myosatellite cells. The muscle was relatively immat... | 596,655 | [
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[Small mammal helminths in Neusiedlersee region]. | 153 small mammals belonging to 22 species were investigated during the year 1975. On this occasion, 29 different species of helminths were found. Parallel-infection of one host by different helminths was common. All age-groups and both sexes of hosts were infested. Pathological symptoms like eosinophile infiltration of... | 596,674 | [
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The brown dog tick Rhipicephalus sanguineus and the dog as experimental hosts of Ehrlichia canis. | Adult Rhipicephalus sanguineus ticks efficiently transmitted Ehrlichia canis to susceptible dogs for 155 days after detachment as engorged nymphs from a dog in the acute phase of ehrlichiosis. Adult ticks that had similarly engorged on a dog in the chronic phase of ehrlichiosis failed to transmit E canis to susceptible... | 596,693 | [
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Ultrastructure of hyaline microthrombi in myocardial capillaries of pigs with spontaneous "mulverry heart disease". | Three 5-week-old pigs from an Indiana farm died of the cardiac form ("mulberry heart disease") of selenium-vitamin E deficiency. Grossly, the hearts had prominent hydropericardium and extensive serosal and myocardial hemorrhage. Histopathologic study demonstrated marked myocardial edema, congestion, and hemorrhage, wit... | 596,707 | [
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Vertical partial laryngectomy for glottic carcinoma with posterior subglottic extension. | Posterior subglottic extension of glottic carcinoma has been a contraindication for partial laryngectomy because of the proximity of the cricoid cartilage. Resection of the upper portion of the posterior aspect of the cricoid is necessary for adequate tumor resection but is complicated by persistent aspiration. This pa... | 596,767 | [
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Late recurrence of a frontal sinus cholesteatoma. | The longest recorded recurrence of a frontal sinus cholesteatoma with involvement of the orbit, frontal bone, and floor of the anterior cranial fossa is presented. Radical surgery is required and often craniotomy is necessary. Bony reconstruction of defects should not be undertaken until recurrence has not been present... | 596,787 | [
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Myocardial protection by continuous coronary perfusion during aortic valve replacement. | The coronary perfusion system used at Oulu University Central Hospital is described and the importance of physiological coronary perfusion stressed. Our method of protecting the myocardium from ischemic injury during aortic valve replacement included the following: phasic constant-pressure coronary perfusion, maintenan... | 596,806 | [
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The distribution of body fat in relation to habitual activity. | 42 young female subjects aged 19-24 years were selected to form 3 groups based on the estimated hours of physical activity taken each week. They represented 1. very active, 2. active, and 3. sedentary people. Their body fat and fat-free mass (FFM) were estimated from densitometry (corrected for the lung residual volume... | 596,819 | [
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A Monte Carlo test of weight as a critical factor in menarche, compared with bone age and measures of height, width, and sexual development. | The correlation coefficients for each of nine traits measured at menarche (bone age, pubic hair and breast stages, and five physical measurements) have been calculated. These have been compared with the corresponding correlation coefficients obtained by using a Monte Carlo technique, where the ages of menarche are rand... | 596,822 | [
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Relative importance of the effect of family environment and heredity on obesity. | In a study using data from 254 families with 546 non-biologically related children and 10 337 families with 25 554 biologically related children an analysis of variance technique was used to evaluate the effect of family environment and heredity for children ages 4-11. Family environment accounted for 32% of the variat... | 596,825 | [
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Bioassay of kinship in northwestern Europe. | Kinship of Barra (Outer Hebrides) is bioassayed as 0.0096 relative to northwestern Europe, in reasonable agreement with prediction of 0.008 relative to Britain. The exponential decline of kinship with distance is similar to Scandinavia. Kinship of larger populations is consistent with predictions from isolates. Kinship... | 596,833 | [
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[Sensitivity of Sherman's propionic acid bacilli to antibacterial preparations and vitamin B12 synthesis]. | Sherman propionic acid bacilli were sensitive to benzylpenicillin, ampicillin, ceporin, tetracyclines, oleandomycin, oletetrin, tetraolean, sigmamycin, levomycetin and furadonine. Methicillin, oxacillin, monomycin, kanamycin, polymyxin and furazolidone had an insignificant effect on the above organism. The subbacterios... | 596,839 | [
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[Formation of peroxide compounds and their role in the inactivation of polyene antibiotics levorin and mycoheptin]. | The kinetics of peroxide formation in the process of levorin and mycoheptin oxidation at a temperature of 57 degrees C was studied. It was shown that the peroxide compounds actively participated in the processes of levorin and mycoheptin inactivation as intermediate products of their transformation. Addition of the per... | 596,845 | [
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Auxotrophic mutants in the selection of the rubomycin producer, Actinomyces coeruleorubidus. | A total of 351 auxotrophic mutants with different antibiotic activity, including several mutants with activity higher than that of the parent prototrophic strains were obtained under the effect of gamma-rays from 3 prototrophic strains of Act. coeruleorubidus. It was shown that most of the auxotrophic mutants did not p... | 596,854 | [
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Killer-sensitive relationships in yeasts from natural habitats. | Yeast strains (157) belonging to at least 9 genera were isolated from natural habitats and screened for killer-sensitive relationships. Killer and sensitive characteristics were exhibited by 17 and 11% of the isolates, respectively. The strains belong to either one of two mutually exclusive killer-sensitive groups. | 596,861 | [
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Ploidy, ascus formation and recombination in Torulaspora (Debaryomyces) hansenii. | X-ray inactivation studies on the type strain of Torulaspora hansenii carried out to determine ploidy, provided proof that the species has a haplontic life cycle, a fact which hitherto has only been presumed. Observations on the genesis of the ascus by light microscopy and transmission electron microscopy provide no ev... | 596,863 | [
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Isolation and identification of pathogenic Naegleria from Florida lakes. | Five cases of primary amoebic meningoencephalitis associated with swimming in freshwater lakes have been recorded in Florida over the past 14 years. The present study demonstrated that pathogenic Naegleria, the causative agent, is relatively widespread. Twelve of 26 lakes sampled only once yielded the amoeba. Populatio... | 596,870 | [
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Limitations of diagnostic value of the sweat test. | The sweat test, even if carried out by an experienced technician, sometimes lacks reproducibility owing presumably to physiological variations (patient's diet, temperature, and other factors at present unrecognized). Some patients are particularly prone to exhibit this variability and in them a single sweat test is alm... | 596,925 | [
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Bladder emptying in neonates. | Ultrasound scanning was used to determine whether bladder emptying is complete when a newborn baby micturates. Residual urine was detected in 6 females and 9 males while one female emptied her bladder completely. The residual volume was estimated in 11 subjects and ranged from 3.9 to 13.9 ml. Incomplete bladder emptyin... | 596,928 | [
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Paraproteinaemia in erythema elevatum diutinum. | Paraproteinaemia (IgGkappa) was observed in a 68 year-old patient with erythema elevatum diutinum. The association of this skin disease with paraproteinaemia as already reported by other authors may indicate a pathogenetic relationship. | 596,932 | [
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Rheumatoid involvement of the lumbar spine. | On stereoscopic examination of the lumbar spines of 6 patients with rheumatoid arthritis and spinal disease we found typical rheumatoid erosions in the apophyseal joints. 2 also had severe asymmetrical disc destruction with associated involvement of the vertebral bodies and scoliosis. In one of these patients who devel... | 596,945 | [
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Behavioral despair in mice: a primary screening test for antidepressants. | A depressed state can be induced in mice by forcing them to swim in a narrow cylinder from which they cannot escape. After a brief period of vigorous activity the mice adopt a characteristic immobile posture which is readily identifiable. Immobility was reduced by tricyclic antidepressants, monoamine oxidase inhibitors... | 596,982 | [
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... |
Induction and properties of guinea pig serum interferon. Preliminary report. | Guinea pigs, 250-350 g body weight, both sexes, were injected with 5X10(8.5) EID50 NDV (Radom strain) intracardially and intraperitoneally simultaneously. The animals were bled by cardiac puncture 0, 3, 6, 12, 24 and 48 hours after injection. After virus inactivation, serum interferon titration was performed in culture... | 597,011 | [
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0.3650758,
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Electromyographic insertional activity mechanically provoked in the biceps brachii. | Clinically, some electromyographers have felt that electrical activity provoked by needle insertion becomes prolonged prior to the development of positive sharp waves and fibrillation potentials in pathologic conditions. The significance of this is unclear as this electrical activity has not been quantitatively studied... | 597,024 | [
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[Perception and evaluation of symptoms in hypochondria (author's transl)]. | Hypochondriacal perception and evaluation of symptoms are discussed as an abnormal cognitive process. From a phenomenological viewpoint, a self-centered focussing on the perception of bodily sensations and a restriction of risk-taking behaviour is emphasized. In behavioral terms, several cognitive mechanisms and concep... | 597,029 | [
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0... |
[Changes in the blood vessels of the spinal cord and spinal ganglia following chronic stimulation of the lumbar regions of the sympathetic trunks and gangliosympathectomy]. | Morphological studies in 40 rabbits demonstrated that chronic irritation of the lumbar sympathetic trunks resulted in more pronounced architectonic changes, in vessel walls and in neurons of the lumbar sympathetic ganglia in 15 days than did the bilateral lumbar gangliosympathectomy at the same time. In both series of ... | 597,045 | [
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... |
[Detection of enterochromaffin cells by the luminescence method with lighting from the side]. | A method is suggested to detect luminescence of enterochromaffin cells of the intestinal tract after a routine fixation of sections in 10% formalin, imbedding in paraffin, and examination under the microscope when the light is directed to the preparation laterally, at the angle of 30--40 degrees. The sections fixed on ... | 597,046 | [
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0.2103468,
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[Histophysiological analysis of adaptation of ecologically different species of sturgeons to hypertonic medium]. | In saplings of Acipensar güldenstädti Brandt while adapting to sea water with salinity of 12.5%, the main functional changes in the chloride cells of the branchiae, the thyroid gland and interrenal tissue occur within the first 12 hours. During this period, concentration of osmotically active substances in blood serum ... | 597,063 | [
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... |
Occurrence of myofibroblasts in the different phases of morbus Dupuytren (Dupuytren's contracture). | Twenty-one surgically removed specimens of Morbus Dupuytren (M. D.) were studied by light and electron microscopy. The cell type observed in the proliferative phase shows the basic ultrastructural features of fibroblasts, while the majority of the cells in the involutional phase resemble myofibroblasts. Myofibroblasts ... | 597,102 | [
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0.4492992,
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Iron-sulphur centres in mitochondria from Arum maculatum spadix with very high rates of cyanide-resistant respiration. | X-band electron-paramagnetic-resonance spectroscopy at 4.2--77K combined with measurements of oxidation-reduction potential was used to identify iron--sulphur centres in Arum maculatum (cuckoo-pint) mitochondria. In the oxidized state a signal with a derivative maximum at g = 2.02 was assigned to succinate dehydrogenas... | 597,230 | [
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0.1178947,
... |
The effects of inhibition of fatty acid oxidation in suckling newborn rats. | Inhibition of fatty acid oxidation with pent-4-enoate in suckling newborn rats caused a fall in blood [glucose] and blood [ketone bodies] and inhibition of gluconeogenesis from lactate. Glucose utilization was not increased in newborn rats injected with pent-4-enoate. Active fatty acid oxidation appears to be essential... | 597,245 | [
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0.3371833,
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Skeletal-muscle sarcolemma from normal and dystrophic mice. Isolation, characterization and lipid composition. | 1. Mouse skeletal-muscle sarcolemma was isolated, and the preparations obtained from normal mouse muscle and from muscle of mice with hereditary muscular dystrophy were characterized with respect to appearance under the optical and electron microscopes, distribution of marker enzymes, histochemical properties and bioch... | 597,270 | [
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0.253011,
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Regression of atheroma in the rabbit. | Ten studies in the literature concerning regression of rabbit atheroma were re-examined. In studies where cholesterol content was referred to weight, a degree of regression was noted in 3/4 studies. Such regression might at least partly have resulted from the dilution effect of the atheroma contents when results were e... | 597,348 | [
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Strain differences in response to dietary cholesterol by JAX rabbits: correlation with esterase patterns. | Six strains of genetically defined JAX rabbits were tested for their serum cholesterol levels (total and free) in response to a 0.5% cholesterol diet. Marked differences in response between the 6 strains were found. IIIVO/J and WH/J are low responding strains, X/J and ACEP/J are intermediate responding strains, and OS/... | 597,351 | [
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Environmental quality induced predicted by evolutionary theory. | The use of evolutionary theory to understand and predict environmental quality indices has been described. Three specific examples concerning the environmental health implications of black skin, heat stress adaptation, and G-6-PD deficiency have been discussed in which evolutionary theory provides the conceptual framew... | 597,389 | [
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0.3786874,
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[Changes in the vaginal mucosal bacterial flora ecosystem during the menstrual cycle in women]. | It was shown that bacteria of mucosae of higher organisms, mostly have specific receptors for chemical complementary structures of cell surface. On the other hand it is known already that vaginal flora changes during ovulation and afterwards, some infections begin and reveal during some periods of the ovulatory cycle. ... | 597,394 | [
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Mononuclear cell-membrane "fluidity": a study in some haematological malignancies. | The polarization of fluorescence from diphenyl hexatriene embedded in the membranes of intact peripheral-blood mononuclear cells has been measured and used to assess the "microviscosity" or fluidity of the membrane. Cell preparations were examined from patients with various types of leukaemia and related conditions in ... | 597,474 | [
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0... |
Polypeptide composition of purified QH2:cytochrome c oxidoreductase from beef-heart mitochondria. | 1. The polypeptide composition of purified QH2: cytochrome c oxidoreductase prepared by three different methods from beef-heart mitochondria has been determined. Polyacrylamide gel electrophoresis in the presence of dodecyl sulphate resolves eight intrinsic polypeptide bands; when, in addition, 8 M urea is present and ... | 597,492 | [
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... |
[Biosynthesis of mitochondrial protein in rat liver under conditions of vitamin B 1 deficiency following oxythiamine injection]. | The incorporation of labelled precursors into mitochondrial proteins of liver under different duration of oxythiamine (antivitamin B1) effect was studied in the whole organism and in a cell-free system. After 24 hrs following the injection, oxythiamine at a dose of 400 mg/kg of body weight increases the mitochondrial p... | 597,522 | [
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0.41... |
Effect of limb restraints on serum creatine phosphokinase activity in normal volunteers. | Increased serum creatine phosphokinase (CPK) activity is sometimes found in acutely psychotic patients. In order to study factors affecting CPK activity, we investigated in normal subjects the effect on serum CPK activity of resistance to being restrained and to struggle against leather limb restraints (LLR) sometimes ... | 597,527 | [
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In vivo metabolism of cannabinol by the mouse and rat and a comparison with a metabolism of delta 1-tetrahydrocannabinol and cannabidiol. | The in vivo liver metabolism of cannabinol has been studied in the mouse and rat by combined gas chromatography and mass spectrometry. Cannabinol glucuronide was the major metabolite of cannabinol in the mouse and was accompanied by relatively large amounts of 7-hydroxycannabinol, cannabinol-7-oic acid and their corres... | 597,586 | [
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On the mapping of chains of first order chemical reactions on random walks. | We present the transient solution to a random walk problem which characterizes chemical kinetic processes in which a particular state may have a finite number of internal states. While there are many chemical and physical examples, we introduce the solution through models of biophysical interest. | 597,589 | [
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[Damage to the isolated heart due to adrenaline perfused with a saline solution]. | Perfusion of the isolated heart with Krebs solution containing 5 and 20 microgram/ml of adrenaline induced cardiocyte micronecrosis. Perfusion with 0.5 microgram/ml of adrenaline induced no micronecrosis. Dispersion analysis showed a statistically significant effect of adrenaline concentrations on the degree of the car... | 597,604 | [
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0.1477697,
... |
[Ultrastructural changes in the parietal cells of persons suffering gastric ulcers]. | Ultrastructural changes taking place in various phases of secretion in the gastric fundus parietal cells after histamine adminstration were studied in patients suffering from gastric and duodenal ulcers, having different gastric acidity. Parietal cells of patients with normal and hyperacidity of the gastric juice after... | 597,615 | [
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0.2560985,
0.07921008,
... |
[Effect of bronchodilators on density dependence of expiratory flow-volume curves. An attempt to localize bronchodilators site of activity (author transl)]. | In order to localize bronchodilators site of activity we studied the maximal expiratory flow-volume curves breathing air and 80 percent-20 percent helium-oxygen mixture in 11 normal and 23 asthmatic children. We measured delta Vmax. 60 percent TLC. delta Vmax. 45 percent TLC and VisoV. Half of the subjects received 400... | 597,640 | [
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A study of predictive factors in depressive disorders of poor outcome. | A retrospective comparison was made between two groups, each consisting of 30 depressed patients, one in which the outcome following discharge had been good, the other where it had been poor. A previous psychiatric history, earlier admission for psychiatric illness, particularly for affective disorders and a poorer per... | 597,686 | [
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0.0174867,
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Social skills training of out-patient groups. A controlled study of rehearsal and homework. | Fifty-one out-patients with social skills deficits (two-thirds men) completed ten weekly sessions of 75-minute group treatment; 44 were followed up for a mean of 16 months. Random assignment was to one of three conditions: (I) Cohesive group discussion; (2) Modelling and role-rehearsal; or (3) Modelling and role-rehear... | 597,688 | [
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0.... |
Long-term follow-up 100 cases of renal calculi. | Phosphatic calculi form in infected urine. Complete clearance is associated with sterile urine. This disease is distinct from metabolic stone disease and should be curable if all stones are removed and postoperative infection is prevented. | 597,694 | [
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Early diagnosis of prostatic carcinoma: the role of transurethral resection. | The exclusion of prostatic carcinoma in TUR specimens represents a considerable problem for the histopathologist. A technique for the separation of tissue on an anatomical basis which has been carried out on 50 patients is presented. It permits more representative histological sampling of TUR specimens and more accurat... | 597,711 | [
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0.1160621,
0.3228566,
0.06556364,
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0.3578182,
0.1457749,
-0.07591295,
... |
The measurement of Ca2+ effluxes from bone. | To facilitate the study of membrane function in the control of the flow of ions into and out of bone, it was desirable to develop a system for the direct quantitation of unidirectional effluxes of calcium and phosphate from bones. Based on a mathematical analysis of the problem, a specially designed Ussing chamber was ... | 597,749 | [
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0.3642615,
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-0.12396... |
Ultrastructural study of amelogenesis imperfecta. | An ultrastructural study of teeth with amelogenesis imperfecta revealed various aspects of microcavities in the enamel surface, which ranged from isolated imprints of ameloblasts corresponding to the mildest lesions at the end of amelogenesis, to pits caused by the death of 20 to 30 ameloblasts at the beginning of amel... | 597,757 | [
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0.4795761,
0.06252573,
0.1006145,
-0.... |
Demonstration of enamel matrix proteins on root-analogue surfaces of rabbit permanent incisor teeth. | The continuously erupting rabbit incisor tooth is normally thought of as having an enamel covered "crown" on its labial surface and a cementum covered "root" on its lingual surface. We have examined both surfaces of continuously erupting rabbit incisor teeth taken from near term embryos by a variety of means, including... | 597,761 | [
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Further observations on the fine structure of cellular cementum from deciduous teeth of pigs. | Examination of microradiographs from the deciduous teeth of pigs revealed large lacunae or radiolucent zones close to the cemento-dentinal junction. Electron microscopic studies of the ground sections showed areas of irregularly shaped zones devoid of mineral and filled with collagen fibers. In the wide unmineralized z... | 597,763 | [
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-... |
Luminescence quantum yields of sound and carious dental enamel. | The absorption and emission spectra of slabs of human and bovine dental enamel were determined. The absorption and scattering coefficients and emission quantum yields were computed according to theoretical models. The samples were gradually demineralized. The absorption, scattering, and emission parameters were determi... | 597,765 | [
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Effect of the linoleic acid concentration of mother's diet on adenyl cyclase activity of fetal and neonatal rat brown adipose tissue. | An adenyl cyclase activity was measurable in the brown adipose tissue of fetal rat, and could be stimulated in vitro by noradrenaline during the last 3 days of fetal life. The stimulating effect of noradrenaline was maximal at birth and decreased during the first days of extrauterine life. Ingestion by mother of a high... | 597,775 | [
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... |
Ultrastructural changes in the mitochondria of brown adipose cells during the hibernation cycle of Citellus lateralis. | The mitochondrial structure in the brown adipose cells of the golden mantled squirrel, Citellus lateralis, was examined throughout the year in biopsy samples. The mitochondria showed remarkable and apparently reversible changes in size and internal structure related to the physiologic activity of the animal. In the act... | 597,844 | [
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Testicular involution following optic enucleation: the Leydig cell. | The testes of Syrian hamsters underwent pronounced involution within six weeks after blinding. The seminiferous tubules were devoid of all stages of spermatid development and mature spermatozoa were absent from the tubule lumina. The diameter of of the Leydig cells was 25% less than that of controls. Examination with t... | 597,849 | [
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Unstable, heterogeneous physical states of nuclear bodies during the post-hepatectomy dedifferentiation-replication-redifferentiation sequence. | Nuclei are shown to undergo generalized changes of state during regeneration, as reflected by changes in equilibrium density of sucrose density gradients. The time-course of these phenomena suggests an association with changes occurring after S-phase and mitosis. Such changes are no longer observable in extensively pur... | 597,867 | [
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[Benign lymphoepithelial lesion of the salivary glands]. | A series of eight observations serves for demonstrating the clinico-pathological picture of the benign lymphoepithelial lesion of salivary glands. The glandular lesion was associated with joint symptoms, one of the female patients developed malignant lymphoma. | 597,920 | [
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... |
A method for the analysis of chlorhexidine in serum. | A colorimetric method for the determination of chlorhexidine in serum or plasma has been elaborated; the limit of detection of the method is 25 ng/ml, based on 10 ml of serum or plasma. | 598,008 | [
-0.221528,
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0.059... |
Serum prolactin and oestradiol levels at different stages of puberty. | Serum prolactin and oestradiol levels were measured in 183 children who were staged for pubertal development. Mean serum prolactin levels are higher in girls than in boys at stage 3 of pubertal development. In girls prolactin levels rise at stage 2, and are higher after menarche; in boys there is no change in prolactin... | 598,012 | [
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Clofibrate treatment of hyperlipidemia in chronic renal failure. | The pharmacokinetics of the hypolipidemic agent, clofibrate have been studied in anuric patients on intermittent hemodialysis. In addition we have tried to determine whether the treatment of hyperlipidemia of chronic renal failure with clofibrate was safe and efficacious. Seven healthy volunteers and five uremic patien... | 598,055 | [
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Compression fractures of the thoracic and lumbar spine from compensable injuries. | Compression fractures of the thoracic and lumbar spine have a worse prognosis than is commonly realized. A study of 142 patients with this type of injury reveals several important features which affect the long term prognosis in these injuries. Severe compression, comminution, disc space narrowing adjacent to the fract... | 598,072 | [
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-0.062142... |
The external compression syndrome of the ulnar nerve at the cubital tunnel. | Diagnosis of the cubital tunnel external compression syndrome, and subsequent avoidance of further external pressure, minimizes the possibility of progressive crippling of the hand. The usual clinical features are local tenderness over the cubital tunnel, often accompanied by distal paresthesias, and neurological defic... | 598,076 | [
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Electrical callus and callus formation by electret. | The callus formed by passing an electric current through bone is called electrodynamic callus. The amount of electrical current determines the quality of the callus (osseous, cartilagenous, or fibrous). Callus forms first at the negative pole and grows toward the positive pole. The callus formed by placing a teflon fil... | 598,093 | [
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... |
Results of posterior iliopsoas transfer for hip instability caused by cerebral palsy. | The incidence of subluxation or dislocation of the hip in 185 cerebral palsied patients was 25.4%. Posterior iliopsoas transfer will decrease hip deformities but complications such as weakness of hip flexion or abduction contracture are to be expected in some cases. Posterior iliopsoas transfer did not give uniformly s... | 598,114 | [
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Diastasis of the tibiofibular mortise, hypoplasia of the tibia, and clubfoot, in a neonate with cleft hand and cardiac anomalies. A case report. | In a newborn girl diastasis of the distal tibiofibula joint was associated with cleft hand deformity, and cardiac anomalies. While at least 3 cases of congenital distal tibiofibular diastasis have been reported previously, this patient seems to be the first to have had hand and cardiac defects. The diastasis is believe... | 598,121 | [
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Salmonella spondylitis. Report of 2 cases. | Two cases of Salmonella spondylitis with unusual features appeared in patients who have no sickle cell disease and no history of typhoid fever. One case presented with paraparesis, was misdiagnosed and originally treated for Pott's disease. The other case was diagnosed correctly by specific laboratory tests, but failed... | 598,125 | [
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-0.01050981,
-0.0163988... |
Milwaukee brace treatment of idiopathic scoliosis: late results. | Forty-seven patients returned for examination, X-ray and statistical analysis of the results more than 5 years after Milwaukee braces had been discontinued. The mean curves showed a characteristic pattern of rapid improvement after the brace was applied and then gradual loss of correction during the follow-up. There wa... | 598,139 | [
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Acute elevation of intracranial pressure following transection of non-functional spinal cord. | A spinal cord which is neurologically nonfunctional may be functioning as a conduit for CSF between the ventricular system and the spinal subarachnoid space. Interruption of this pathway can have catastrophic consequences unless there is an adequately functioning shunt. | 598,174 | [
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0.2397... |
Analysis of sudden deaths in a district of Bohemia in the period 1971--1973. | A clinico-pathologico-anatomical analysis of 150 cases of sudden death in a district of Bohemia in the period 1971--1973 revealed coronary atherosclerosis as the most frequent cause of sudden death(87.3%); stenosing coronary atherosclerosis without postmortally detectable myocardial necrosis participated by 71.7% in th... | 598,200 | [
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Investigations of capillary network in the myocardium, skeletal muscles, and other organs by modified Gomori's method for determination of acid phosphatase activity. | A modification of Gomori's sulfide method for the determination of acid phosphatase activity is presented, which visualizes the walls of all capillaries in the myocardium, skeletal muscles, synovial membranes, and some other organs (liver, kidney). Blocks of investigated organs (edge lengths 2--3 mm) are cold-fixed in ... | 598,209 | [
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... |
An equation illustrating the relationship between haemodynamic factors and renal sodium excretion. | An equation is presented permitting to assess quantitatively the interrelationships between principal haemodynamic factors (mean blood pressure, renal venous pressure, filtration fraction, renal vascular resistance) and factors influencing the renal sodium excretion (glomerular filtration rate, fractional tubular sodiu... | 598,212 | [
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-0.0720517... |
Five early milestones in premature infants. | The onset of five early milestones was studied in premature and full-term infants. The milestones are: recognition of mother's voice and face, 3-month smile, following through 180 degrees, and two hand-eye coordination. It was hypothesized that premature infants would show delay in acquiring milestones related to time ... | 598,258 | [
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... |
The respiratory tract and the environment. | The primary determinants of pulmonary disease are environmental. The same thinness and delicacy of the air-blood barrier which allows rapid exchange of oxygen and carbon dioxide also reduce its effectiveness as a barrier to inhaled allergens, carcinogens, toxic particles, and noxious gases, and micro-organisms. Adults ... | 598,343 | [
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Background information on high voltage fields. | The increased demand for power has led to higher voltages for overhead transmission lines. Environmentalists, governmental agencies, and some members of the scientific community have questioned if past biological effects research and experience with lower voltage lines provide adequate bases for predicting the possible... | 598,346 | [
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Environmental factors and the development of disease and injury in the alimentary tract. | This review examines interactions between the alimentary tract and environmental agents. In these intera"ctions the alimentary tract is considered as an integrated organ system extending from mouth to anus. The alimentary tract shares with the skin and its appendages and the respiratory system the distinction of being ... | 598,351 | [
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-0.4071408,
... |
Exercise-induced changes in blood ammonia levels in humans. | Five male and two female subjects each performed a maximal aerobic capacity (VO2 max) test, and two to four submaximal aerobic exercise bouts (requiring approximately 50 and 80% of the individual's measured VO2 max) on a motor-driven treadmill. Pre-exercise resting oxygen uptakes (VO2) and heart rates were determined a... | 598,363 | [
-0.3527816,
0.1961638,
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0.1440063,
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0.1146111,
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0.3078221,
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0.3333071,
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... |
Stereochemistry of olefinic bond formation in defensive steroids of Acilius sulcatus (Dytiscidae). | The defensive secretion of Acilius sulcatus contains a number of pregnane derivates: cortexone, 20alpha-hydroxy-4-pregnen-3-one, together with the unusual delta4,6 dienes, 6,7-dehydrocortexone, 20alpha-hydroxy-4,6-pregnadien-3-one and 4,6-pregnadien-3,20-dione. The synthesis of all these steroids except cortexone is de... | 598,371 | [
-0.07690353,
0.1876543,
0.2058353,
0.02107876,
0.04233969,
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0.2719225,
0.09604893,
0.04032658,
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0.08070498,
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0.2291034,
0.1819731,
0.2844951,
0.5919838,
-0.1291113,
-0.2736436,
... |
Comparison of the pharmacodynamic effects of furosemide and BAY g 2821 and correlation of the pharmacodynamics and pharmacokinetics of BAY g 2821 (muzolimine). | In a biometrically planned, double-blind study on 12 Oedema-free male patients the saluretic effect of muzolimine 30 mg was compared with furosemide 40 mg. The plasma level of muzolimine was determined and correlated with its pharmacodynamics. In terms of excretion during the 12-hour observation period muzolimine 30 mg... | 598,405 | [
-0.09413853,
0.1770518,
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0.004822264,
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0.1323656,
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0.0704302,
0.2743205,
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0.1823204,
0.3817843,
0.3811328,
0.006111709... |
Human pharmacokinetics and bioavailability of temazepam administered in soft gelatin capsules. | Plasma levels of temazepam were determined in healthy subjects after single oral administration of soft and hard gelatin capsules, and after 7 consecutive night-time doses in soft capsules. Absorption from soft gelatin capsules was significantly faster and produced earlier and higher peak plasma levels. The two pharmac... | 598,411 | [
-0.1719884,
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0.2224394,
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0.4273574,
0.2591627,
0.08986051,
-0.1... |
The pharmacokinetics of carbamazepine. | The time-courses of plasma carbamazepine concentrations were followed in six apparently healthy adult subjects who, at different times, took single oral drug doses of 200, 400, 500, 600, 700, 800 and 900 mg. There were some suggestions of impaired bioavailability of the drug when given in tablet form. The following val... | 598,420 | [
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0.1154796,
0.2490006,
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0.2527047,
0.07541203,
-0.004442203,
0.05425118,
0.5236829,
0.01952178,
0... |
Pharmacokinetic and concentration-effect relationships of clonidine in essential hypertension. | The effect of oral doses of 300 microgram of clonidine hydrochloride on blood pressure, sedation and saliva production in 5 essential hypertensives were qualitatively similar to the effects in normotensive subjects. Peak plasma clonidine concentration (1.34 +/- 0.28 ng/ml) and plasma half-life (10.0 +/- 0.8 h) were sim... | 598,422 | [
0.1141593,
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0.2307435,
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0.06090628,
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0.06210058,
0.2268789,
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0.2384481,
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0.03951843,
0.02548082,
0.1971871,
-0.05439933,
0.1576235,
0.1709031,
... |
The retinal input to cells in area 17 of the cat's cortex. | The activity of retinal ganglion cells and cortical cells with overlapping receptive fields was simultaneously recorded. The responses to moving stimuli of individual simple cortical cells could be accounted for on the basis of the cell receiving either on-centre or off-centre afferents; instances in which it was neces... | 598,438 | [
-0.005754136,
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0.1118984,
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0.03114962,
0.2319935,
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0.2085193,
0.2419461,
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0.1647526,
0.2185381,
0.05507586,
0.2091543,
0.392282,
0.06264803,
... |
Human cell cultures infected by tumor-inducing and non-tumor-inducing viruses, an electron microscopic study. | This study is dealing with the infection patterns of adenovirus type 2 and type 12 on human fibroblast cell lines, KB, WI and MAF. With the exception of Ad -12 leads to WI, many intranuclear viral particles were present. None of these second passages (Ad-2 WI-WI, Ad-12 WI-WI, Ad-2 MAF-MAF, Ad-12 MAF-MAF) was found to h... | 598,460 | [
-0.3931424,
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0.3327099,
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0.2723483,
0.01970001,
0.03414384,
0.03481942,
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0.1496742,
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-0.2046416,
0.001715515,
0.1669332,
0.1392291,
0.5493656,
0.007674056,
-0.3136343,
... |
[Effect of phentolamine on the electroencephalogram and pulse activity of the cortical neurons]. | In tests with vigilant immobilized and also urethan anesthetized rabbits the influence of intravenous injection of phentolamine (3--10 mg/kg) on the EEG waves parameters was studied. It is shown that within 45 to 75 minutes following introduction of phentolamine there is observed either shortening or elimination of the... | 598,491 | [
0.1379799,
-0.09725854,
-0.2697699,
-0.2584823,
0.2720498,
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-0.3283848,
-0.005807815,
0.04074292,
0.1206614,
-0.04209476,
-0.01653366,
-0.5360068,
-0.04062612,
-0.8430901,
0.3063025,
0.06074817,
0.1973287,
0.3930055,
0.0789165,
0.2977653... |
[Effect of imipramine on the vasomotor tone, blood supply and activity of the heart]. | In tests conducted on anesthetized cats it was shown that imipramine used in doses of 1 and 3 mg/kg causes hypertension, increases the vascular tone in the kidneys and limbs. In doses of 5 and 10 mg/kg the drug provokes a short-lived (1--3 minutes) hypertension with a subsequent prolonged drop of the arterial pressure.... | 598,497 | [
-0.3256801,
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-0.09649605,
-0.2393999,
0.02376534,
-0.3889304,
-0.2661334,
-0.1480633,
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-0.4087908,
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0.06486057,
0.1447011,
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-0.5792048,
0.1565487,
-0.1075548,
0.4340189,
0.03878122,
0.07077201,
0.0971700... |
[Effect of prostaglandins E1 and E2 on the adrenergic reactions of the cerebral vessels]. | Prostaglandins E1 and E2 were found to lower the pressor effects of norepinephrine and sympathetic stimulation with respect to the cerebral vessels in cats. This property is more marked in prostaglandin E1. Inhibition of the prostaglandins biosynthesis with indometacin leads to intensification of the described antagoni... | 598,494 | [
-0.06932899,
-0.07052577,
0.07321937,
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0.2044128,
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0.09110735,
0.06432673,
-0.0406597,
-0.3090406,
0.213596,
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-0.3497365,
-0.02230363,
-0.1795289,
0.502463,
0.114733,
-0.1406326,
-0.0659553... |
[Trace effects of short-term cooling and their importance in the adaptation to cold]. | The thermoregulation traces (O2 consumption, electrical activity of cervical muscles deep rectal temperature and subcutis temperature) were observed to 30 min. at ambient temperatures + 20--24 degrees and + 6--7 degrees through 1, 5, 10 and 30 days after cooling. The after-effect (traces) of cooling depends on conditio... | 598,545 | [
-0.05177239,
-0.4083505,
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0.1478665,
0.04087862,
-0.1504797,
0.05519451,
0.3380723,
-0.4477651,
-0.5863082,
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-0.5763704,
-0.1093794,
-0.1240771,
0.2413515,
0.2393419,
0.3773453,
-0.04501468... |
The measurement of obsessionality: first validation studies of the Lynfield obsessional/compulsive questionnaires. | The difficulties encountered in attempts at the rating and quantification of obsessional behaviour are outlined and some of the reasons for such difficulties are mentioned. The development of the Lynfield Obsessional-Compulsive Questionnaire from the Leyton Obsessional Inventory is discussed together with the advantage... | 598,601 | [
0.06116997,
0.2267223,
-0.08996694,
-0.1328879,
0.132528,
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-0.1653598,
-0.009642712,
-0.07731698,
0.1039734,
0.05439404,
0.0779423,
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-0.4658842,
0.222321,
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0.3690866,
0.1261751,
0.0440173,
0.09879486,
... |
Clomipramine (Anafranil) in depressive patients with obsessive neurosis. | The authors express the view that, clinically, clomipramine (Anafranil, Geigy Pharmaceuticals) seems to be the treatment of choice for obsessive-compulsive illness. Clomipramine possesses a specific anti-obsessional property which is distinct from its antidepressant property. The optimal therapeutic dose from this stud... | 598,603 | [
-0.3053628,
0.06747211,
-0.2016485,
0.02748773,
0.4637097,
-0.292764,
-0.2952752,
-0.1153035,
-0.1484271,
-0.2338839,
0.06882187,
0.6988766,
0.3876488,
0.0336818,
-0.3387524,
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0.2610917,
0.04804519,
0.1201232,
-0.03660314,
0.1797951,
-0.06041547,
... |
Clinical experience in the treatment of phobic disorders. | The author describes his experience in treating phobic disorders with both parenteral and oral clomipramine. Other techniques are mentioned and it is suggested that it is not only possible, but also desirable, to incorporate some of these in a regime of parenteral therapy for hospital in-patients. It is recommended tha... | 598,606 | [
-0.443671,
-0.08083478,
-0.3308528,
-0.1137325,
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-0.2207125,
0.3328959,
0.5701766,
0.04715843,
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0.1631047,
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0.01211551,
0.3190306,
0.06410698,
0.07988168,
... |
Damage and repair of DNA in urinary bladder epithelium of rats treated with N-butyl-N-(4-hydroxybutyl) nitrosamine. | N-Butyl-N-(4-hydroxybutyl) nitrosamine (BBN), which selectively induced urinary bladder tumors in several experimental animal species, was found to cause damage of DNA in the bladder epithelium. Wistar strain rats were given 100 mg/kg of BBN intravesically and killed after 2, 6, 12, 24, or 48 hr. DNA damage was examine... | 598,647 | [
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0.2545468,
0.2129511,
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0.001278371,
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0.06311371,
0.4611239,
0.191843,
0.5159717,
0.3254519,
0.1578776,
... |
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