title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Motor nerve conduction velocities in Leigh's encephalomyelopathy. | Slowed motor nerve conduction velocities were found in 3 of 4 cases of Leigh's subacute necrotising encephalopathy. 2 of the patients are sibs, one of whom is clinically normal apart from lactic acidosis and slowed motor nerver conduction velocities. | 626,521 | [
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Psychological determinants of infantile pyloric stenosis. | In order to investigate the possible contribution of maternal emotional stress to the aetiology of infantile pyloric stenosis, 100 mothers of affected infants, 100 "normal" controls who had not sought medical advice at any time concerning feeding problems, and 50 mothers of children with spina bifida were interviewed. ... | 626,522 | [
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Thoracic traction for median sternotomy dehiscence. | Standard management of median sternotomy dehiscence sometimes fails to achieve lasting reduction and fixation of the sternal halves. An effective method of external thoracic traction that augments internal fixation of the sternal fracture is presented. | 626,536 | [
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Appendiceal abscess revisited. | Appendiceal abscess developed in 2% of 2,621 patients with acute appendicitis seen between 1962 and 1976. While representing a commendable decline in frequency from earlier studies, in view of the demonstrated prolonged delay in seeking medical care, further decreases in incidence could be affected by increased patient... | 626,573 | [
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Abnormalities of phenylalanine and tyrosine kinetics. Significance in septic and nonseptic burned patients. | The flow of phenylalanine, the essential amino acid precursor of thyroid hormone and catecholamines, was severely elevated in five septic burned patients (6.70 +/- 1.07 mg/kg) and six nonseptic burned patients (5.00 +/- 0.44 mg/kg) when compared with seven normal controls (2.10 +/- 0.33 mg/kg). Fasting serum concentrat... | 626,574 | [
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Evidence for phenotypic mixing between newcastle disease virus (NDV) and a latent virus of BHK 21/WI-2 cells in the early passaged BHK21/WI-2 cells persistently infected with NDV. | NDV variants released from the early passaged BHK21/WI-2 cells persistently infected with NDV carry the structural antigen of a latent virus of BHK21/WI-2 cells as a result of phenotypic mixing between NDV and the latent virus. | 626,590 | [
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[Mathematical relationship between the dimensions of the auditory ossicles and fetal age]. | Having applied morphometric data obtained on more than 400 auditory ossicles from prefetuses and fetuses at different stages of intrauterine development, the dynamic changes of the greatest size of the malleus, incus and stapes were investigated in age aspect. Increase in size of the auditory ossicles was stated to occ... | 626,599 | [
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[Cytophotometric study of the DNA concentration in the supraoptic neurosecretory nuclei of the hypothalamus]. | DNA content and distribution in supraoptic neuronal nuclei and in their satellites was studied in human subjects died under different conditions of hypothalamo-hypo-physeal neurosecretory activity: moderate (control) and high. In control observations, prevalence of diploid and paradiploid nuclei both in the secretory n... | 626,602 | [
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[Gammagraphic diagnosis of diaphragmatic abnormalities in children]. | Hepatic and lung scanning were evaluated as complement methods of congenital defects in the diaphragm, 14 cases were evaluated in which the scan showed alteration on the morphology and function of the liver or lung. On 13 cases correlation was found between the surgical diagnosis and the scan. In 4 cases with diaphragm... | 626,649 | [
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Demonstration of pulmonary arteries by contrast injection into pulmonary vein. | Pulmonary venous injection of contrast medium in the near-wedge position produced a flow into the pulmonary arterial tree in 15 out of 21 children with cyanotic congenital heart disease. In 5 there was good opacification of both sides from a single injection. The technique provides an additional method of demonstrating... | 626,663 | [
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[Myopathy and hypothyroidism]. | Muscular disturbances in hypothyroid children are: generalized muscular weakness of proximal predominance, muscular hypotonicity, pseudohypertrophy (of gastrocnemius muscles chiefly), slow relaxation stage of osteotendinous reflexes, rise of muscular enzymes (CPK andaldolase), unspecific electromyographic changes and h... | 626,657 | [
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Computer-assisted review of digoxin therapy in the elderly. | Current practice with digoxin was assessed in a group of 42 elderly patients by comparing plasma digoxin concentrations attained on previously established maintenance doses with those generated by a computer programme designed to calculate dosage schedules to suit individual patients. Discrepancies between measured and... | 626,668 | [
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Suxamethonium-induced muscle contracture following traumatic denervation in man. | The effects of the systemic and of the i.v. regional administration of suxamethonium were investigated in 23 patients with traumatic nerve injury. Following the systemic administration of suxamethonium 100 mg, normally innervated muscles showed muscle fasciculations initially, followed by muscular relaxation. On the ot... | 626,701 | [
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Oral psoralen photochemotherapy of atopic eczema. | Oral administration of 8-methoxypsoralen followed by exposure to a high-intensity longwave ultraviolet treatment system resulted in clearing of atopic eczema in 15 patients. Paired-comparison studies demonstrated that this treatment was superior both to conventional ultraviolet light therapy and to no treatment. Short-... | 626,712 | [
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Lymphocytotoxicity in mycosis fungoides. | The phenomenon of lymphocytotoxicity was demonstrated in 29 patients with mycosis fungoides, using a newly described epithelial cell culture system and an isotope marker, 125Iododeoxyuridine (125IUdR). Lymphocytotoxicity was demonstrated in patients in the generalized plaque and the erythroderma phases of the disease (... | 626,717 | [
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Risk of pre-term delivery in patients with previous pre-term delivery and/or abortion. | Patients with a history of two or more pregnancies which ended spontaneously before 37 weeks gestation had an increased risk of spontaneous pre-term labour and delivery in future pregnancies. This increased risk related mainly to previous second trimester abortions and not to previous first trimester abortions. Patient... | 626,728 | [
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Charge-pulse relaxation studies with lipid bilayer membranes modified by alamethicin. | Charge-pulse relaxation studies with the alamethicin-lipid membrane system reveal a triphasic decay of membrane voltage. At short times (resolution time 2 microseconds), where a voltage decay due to the orientation of alamethicin dipoles from the interface into the membranes interior ("gating current") could possibly b... | 626,734 | [
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Spin-orbit couplings in the DNA base pairs. | The radiative lifetimes of the phosphorescent states of the adenine.thymine (A.T) and guanine.cytosine (G.C) base pairs were calculated on the basis of the singlet-triplet transition probability induced by spin-orbit couplings. The calculated radiative lifetimes averaged over the triplet sublevels of spin state were in... | 626,750 | [
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Reduced glucose transport and increased binding of insulin in adipocytes from diabetic and fasted rats. | 1. Animals made diabetic by injection of streptozotocin or animals after 3 days of fasting show decreased insulin levels and a decrease in mean cell diameter of adipocytes from epidydymal fat pads in comparison with cells from normal animals. 2. 14CO2 production from D-[U-14C]glucose is impaired in diabetic and fasted ... | 626,754 | [
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Direct measurement of pure absorbance spectra of living phototrophic microorganisms. | The pure absorbance of turbid cell suspensions of various phototrophic microorganisms were determined by collecting the scattered light. A conventional spectrophotometer was used, equipped with an intergrating sphere as receiver unit, which allowed precise measurements of the absorbance in the range from zero to 0.1. I... | 626,755 | [
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[Spermine and spermidine polyamines in the brain and liver of rats under hyperoxic action]. | The effect of hyperbaric oxygenation (6 atmospheres) on the content of polyamines spermine and spermidine in the rat brain and liver was studied. A decrease of the spermidine content in the brain and liver during oxygen convulsions and four hours after decompression was revealed. The spermine content in the brain durin... | 626,775 | [
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[Reduction of the prereplicative period of the mitotic cycle in hepatocytes on repeated stimulation of divisions]. | Repeated stimulation of division soon after the primary one (2--3 days later) induces a shorteining of the prereplicative phase of the mitotic cylce of hepatocytes to 9--10 hours in the regenerating rat liver. The cells dividing repeatedly after one stimulation were found to pass through the G1-phase of the second mito... | 626,784 | [
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[Characteristics of the estradiol receptor system of the anterior hypothalamus and adenohypophysis in guinea pigs]. | The presence of a specific receptor system (E2-R) wthith low capacity and high stability of the E2-R complex formation was shown in the guinea pig adenohypophysis and anterior hypothalamus cytozols under the vivo and in vitro conditions. Some parameters of the physico-chemical properties of the E2-R system in these tis... | 626,786 | [
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Work analysis by random sampling. | Random sampling of work activities using an electronic random alarm mechanism provided a simple and effective way to determine how time was divided between various activities. At each random alarm the subject simply recorded the time and the activity. Analysis of the data led to reassignment of staff functions and also... | 626,793 | [
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Ioglycamide (Biligram) studies in man--relation between plasma concentration and billary excretion. | Plasma ioglycamide concentration was linearly related to the rate of intravenous infusion over a dose range of from 1 to 4 mg per kg per min. The relation between plasma and biliary concentration of ioglycamide was studied in 15 anicteric patients with a T-tube in situ. Peak biliary concentrations and excretory rates o... | 626,810 | [
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Radiological findings in neurosarcoidosis. | The radiological investigation of neurosarcoidosis is discussed in relation to a series of 32 patients presenting to a neurological hospital. Cranial computed axial tomography, performed in 13 of these cases, was the most frequently positive procedure (77%). The indications for air studies are now limited but in cases ... | 626,816 | [
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Endoscopic retrograde cholangiography in hepatic hydatid disease. | Endoscopic retrograde cholangiography provides safe preoperative documentation of the relationship of hepatic hydatid cysts to the biliary ductal system and accurate distinction from coincident calculus disease. | 626,820 | [
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Duodenal ulcer and working-class mobility in an African population in South Africa. | The number of Africans in Johannesburg presenting with duodenal ulcers has steadily increased over the past 50 years. The characteristics of 105 patients with duodenal ulcer who presented a Baragwanath Hospital were compared with those of matched and unmatched samples of patients without gastrointestinal conditions in ... | 626,837 | [
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Qualitative and quantitative odour discrimation by mitral cells as compared to anterior olfactory nucleus cells. | The responses to odour stimulation of 61 single mitral cells and of 64 single anterior olfactory nucleus (AON) units were simultaneously recorded from rabbits. The test battery consisted of 6 chemical stimuli delivered at two intensity levels corresponding to a hundred-fold difference in concentration. The odour discri... | 626,912 | [
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... |
Value of 111Indium chloride bone marrow scanning in the differential diagnosis of blood count depression in lymphoma. | In patients with Hodgkin's disease or non-Hodgkin's lymphoma, the etiology of low peripheral blood counts is often difficult to determine. Often it is based on the results of a "random" bone marrow biopsy and/or aspirate, plus evaluation of circulating peripheral blood elements. However, these tests may be misleading. ... | 626,925 | [
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0.3288429,
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0.1347236... |
The significance of vascular invasion and lymphocytic infiltration in invasive cervical cancer. | Surgical specimens from 100 patients with stage I B cervical cancer undergoing radical hysterectomy and pelvic lymphadenectomy were reviewed with respect to vascular invasion and lymphoplasmacytic infiltration. Lymph nodes from these patients were classified morphologically according to the criteria proposed by Cottier... | 626,931 | [
0.2739256,
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... |
Clear cell sarcoma with melanin: report of two cases. | Two cases of clear cell sarcoma, one with many melanin pigmented cells and the other scanty, are described. Both are associated with tendons of the lower extremities of young Chinese adults. Their clinical behaviour differed vastly; one patient was dead seven months after local excision and block dissection of regional... | 626,932 | [
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0.2... |
Is the risk of morbidity and rare mortality worth the cure? | Many more children with cancer are being cured, often as a result of aggressive treatment regimens. These employ several modalities and multiple chemotherapeutic agents. The acute complications resulting from this type of treatment are relatively well known. Those that develop later are becoming better understood; some... | 626,942 | [
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0... |
The influence of 5-fluorouracil on cellular and humoral immunity in cancer patients. | The effects of 5-fluorouracil (5-FU) on the immune functions of twelve patients with disseminated cancer were studied, using as parameters the peripheral blood lymphocyte count, serum immunoglobulin levels, titers of natural blood group antibodies, percentages of E and EAC rosette forming cells, and lymphocyte prolifer... | 626,944 | [
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Glucocorticoid-binding components in human thymus hyperplasia. | Preliminary experiments on thymocyte suspensions derived from human thymus hyperplasia indicated the presence of specific cytoplasmic receptors binding [3H]-dexamethasone with high affinity and specificity. The receptor was rapidly transferred into the nuclei at 28 degrees but not at 2 degrees. With cell-free preparati... | 626,957 | [
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0.5528172,
0.1303646,
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Skin tumor-initiating activities of the twelve isomeric phenols of benzo(a)pyrene. | The skin tumor-initiating activities of the 12 isomeric phenols of benzo(a)pyrene (BP) were determined in mice by use of a two-stage system of tumorigenesis. 11-Hydroxybenzo(a)pyrene was moderately active, whereas 2-hydroxybenzo(a)pyrene and BP were strong tumor initiators when applied topically to CD-1 mice and follow... | 626,971 | [
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0.4997668,
0.3674005,
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... |
Exceptional carcinogenic activity of benz[a]anthracene 3,4-dihydrodiol in the newborn mouse and the bay region theory. | Benz[a]anthracene and the five metabolically possible trans-dihydrodiols of benz[a]anthracene were tested for carcinogenicity in newborn Swiss-Webster mice. Four hundred, 800, and 1600 nmoles hydrocarbon i.p. were sequentially injected on Days 1, 8, and 15 of life. The mice were killed at 22 weeks of age. Of the mice t... | 626,973 | [
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0.4858833,
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... |
Leukemoid reaction in BALB/c mice bearing primary tumors induced by 3-methylcholanthrene. | During the growth of five of ten primary tumors that were induced by 3-methylcholanthrene in BALB/cMk and BALB/cMk X C57BL/6F1 mice, leukemoid reactions, characterized by increase in number of granulocytes in peripheral blood, and splenomegaly were observed. However, no such reactions occurred in five C57BL/6 mice bear... | 626,975 | [
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Alterations in serum glycosyltransferases and 5'-nucleotidase in breast cancer patients. | We have measured sialyltransferase, galactosyltransferase, and fucosyltransferase as sell as 5'-nucleotidase in the serum of breast cancer patients. Serum sialyltransferase values in 65 normal healthy females ranged from 2.6 to 8.5 units, with a mean of 5.4. In 25 women with operable primary breast cancer, serum sialyl... | 626,976 | [
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0.2867203,
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DNA repair in normal and preneoplastic mammary tissues. | The purpose of this investigation was to obtain a comparative measure of DNA repair synthesis in hormone-dependent normal mammary tissue and hormone-independent D1 hyperplastic alveolar nodule (HAN) outgrowth. Treatment of mammary fragments in culture with 5 mM hydroxyurea inhibits 98% of the semiconservative DNA synth... | 626,977 | [
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Retinoic acid inhibition of the comitogenic action of mezerein and phorbol esters in bovine lymphocytes. | 12-O-Tetradecanoylphorbol-13-acetate (TPA) is an effective comitogen in phytohemagglutinin-treated bovine lymphocytes. Concurrent addition of 10(-8) M TPA gives a greater than 6-fold increase in DNA synthesis over cultures treated with the lectin alone. The delayed addition of phorbol ester, relative to the start of th... | 626,980 | [
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Early steps in mutagenesis by hycanthone. | Hycanthone, the most potent mutagen in a series of nine thiaxanthenones, is a potent inducer of nuclear immunoreactivity to antinucleoside antibodies in HeLa cells. This response indicates exposure of single-stranded DNA regions. All classes of mutagens thus far tested share this property with hycanthone. Immunoreactiv... | 626,982 | [
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0.2388764,
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Metastatic cloacogenic carcinoma of the anus: sequential responses to adriamycin and cis-dichlorodiammineplatinum(II). | A case of cloacogenic carcinoma of the anus with pulmonary metastases successfully treated with adriamycin and subsequently with cis-dichlorodiammineplatinum(II) (CDP) is reviewed. Cloacogenic carcinoma of the anus is a very uncommon tumor, and this is the first report of a major response to chemotherapy alone. Adriamy... | 627,000 | [
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Pharmaceutical assessment of amygdalin (Laetrile) products. | The National Cancer Institute (NCI) recently acquired a large supply of formulated products of amygdalin manufactured by Cyto Pharma of Mexico, for possible use in a clinical trial in the US. Tablets for oral administration and ampules of the injectable produce were obtained. Both forms were extensively analyzed and ev... | 627,001 | [
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... |
Coronary involvement after a single myocardial infarction. Coronary angiography study. | Coronary angiography was performed in 95 patients 3 months to 3 years after a single myocardial infarction. The patients were categorized into 4 groups according to coronary angiography findings: group I with three or four vessels diseased; group II with two vessels diseased; group III with one vessel diseased, and gro... | 627,002 | [
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Electrocardiographic findings before and after surgery for atrial septal defect of the secundum type in middle-aged patients. | Surgery for atrial septal defect of the secundum type was performed in 84 patients over 40 years of age. Electrocardiograms were studied preoperatively and at a follow-up visit 74 months (range 22-174 months) after surgery. Preoperatively, atrial fibrillation was observed in 13% of the patients, complete right bundle b... | 627,006 | [
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... |
An ultrastructural study of the larval integument of the midge, Chironomus riparius Meigen (diptera: chironomidae). | The larval integument of the midge, Chironomus riparius Mg., is unusually thin although it conforms with the normal insect pattern. The cuticle of the post-cephalic segments is about 3 micrometer thick and overlies an epidermis which has an irregular basal plasma membrane resulting in spaces occurring between it and th... | 627,023 | [
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... |
The growth of follicles in the rat ovary under the influence of busulphan and endoxan. | Busulphan and Endoxan inhibit the normal course of ovarian follicular growth. Older secondary as well as an antral follicles perish within a very short time. Growing follicles, which at the beginning of the experiment exhibited only one layer, remained intact and single-layered during the entire duration of the experim... | 627,024 | [
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Ultrastructural changes in the fat body of adult female Aedes aegypti in relationship to vitellogenin synthesis. | The ultrastructure of the fat body of Aedes aegypti was followed from emergence through a blood meal. Changes in the volume of protein granules and lipid droplets were also examined. The relationship of these events to the known endocrinology of vitellogenin synthesis in mosquitoes is discussed. | 627,029 | [
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The danger of "yellow dyes" (tartrazine) to allergic subjects. | Oral administration of 50 mg tartrazine to 122 patients with a variety of allergic disorders caused the following reactions: general weakness, heatwaves, palpitations, blurred vision, rhinorrhoea, feeling of suffocation, pruritus and urticaria. There was activation of the fibrinolytic pathway as shown by reduction of p... | 627,044 | [
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0.... |
Pitfalls of the alcohol dehydrogenase procedure for the emergency assay of alcohol: a case study of isopropanol overdose. | We describe a case of ethanol and isopropanol ingestion that resulted in coma. The concentration of ethanol and isopropanol was 0.90 and 1.65 g/liter in serum and 3.12 and 5.34 g/liter in gastric contents. With an enzymatic (alcohol dehydrogenase) method for ethanol determination we obtained erroneous analytical result... | 627,079 | [
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0.407831,
0.1344715,
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-0.01327768... |
Osteopathia striata with cranial sclerosis. An autosomal dominant entity. | The syndromic association of striae in the long bones and pelvis, together with sclerosis of the base of the skull, has been investigated in four families. Impairment of hearing and alteration in the shape of the head are the most important clinical manifestations. Spinal abnormalities are an inconsistent feature. The ... | 627,110 | [
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0.3661189,
0.2040122,
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Prenatal diagnosis of 5p-. | With the combination of the various banding techniques (G,Q, and R), a small deletion of the short arm of a No.5 chromosome was detected prenatally in the pregnancy of a 39-year-old woman. The deletion appeared to be either intersitial in nature, involving part of p13 and p14, or the result of a translocation with dele... | 627,112 | [
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0.3113156,
0.007799795,... |
Increase in diuretic effect of chlorothiazide by probenecid. | Thiazide diuretics reach their presumed intraluminal site of action by active transport at the organic acid secretory site of the proximal tubule. Probenecid competes for this transport and might therefore affect the diuresis induced by thiazide at that site. Doses of 500 mg and 1 gm of chlorothiazide (CTZ) intravenous... | 627,130 | [
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0.1067772,
-... |
Hemodynamic and respiratory effects of morphine and butorphanol. | The hemodynamic effects of butorphanol, a potent synthetic narcotic-antagonist analgesic, were investigated and compared with those of morphine. A total of 20 patients were studied (8 butorphanol, 12 morphine) at the time of diagnostic cardiac catheterization. Butorphanol decreased pH, PCO2, and systemic artery pressur... | 627,133 | [
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0.06131651,
0.07193... |
Phenobarbital pharmacokinetics in neonates. | Phenobarbital pharmacokinetics after intravenous injection were studied in 8 neonates with seizures. Subjects ranged in gestational age from 30 to 40 wk. Plasma concentrations of phenobarbital were measured by enzyme-multiplied immunoassay (EMIT). The volume of distribution (Vd) of phenobarbital was 0.97 +/- .15 L/kg w... | 627,141 | [
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[Transcutaneous PO2 measurement in postoperative monitoring following thoracic surgery]. | Continuous transcutaneous PO2 measurement controlling the arterial PO2 was performed in 40 patients undergoing thoracotomy. The close correlation between the PO2 levels measured transcutaneously and those found in the capillary blood prove that the method is very suitable for monitoring the postoperative course after t... | 627,159 | [
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Association of binding sites for guanine nucleotides with adenylate cyclase activation in rat pancreatic plasma membranes. Interaction of gastrointestinal hormones. | 1. The activation of rat pancreatic adenylate cyclase by guanosine 5'-(beta-gamma-imido)triphosphate (p[NH]ppG) and GTP, and by the two gastrointestinal hormones pancreozymin (as C-terminal octapeptide) and secretin was correlated with the binding of [8-3H]guanosine 5'-(beta-gamma-imido)triphosphate to rat pancreatic p... | 627,213 | [
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A simple screening method for detecting gastrointestinal protein loss in intestinal lymphangiectasia. | A ten month old female Turkish child with chylous ascites, diarrhea, steatorrhea, peripheral edema and hypoproteinemia was investigated for protein losing enteropathy which probably dated from the first weeks of life. Gastrointestinal protein loss appeared to be due to abnormalities of the intestinal lymphatics. In ord... | 627,217 | [
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Hemolytic pattern of erythrocytes in the newborn measured by the coil planet centrifuge system and its relationship to neonatal jaundice. | Dynamic osmotic fragility of erythrocytes in cord blood and its changes during the neonatal period were studied by means of a coil planet centrifuge system. The starting-point for hemolysis in the newborn become similar to that of adult blood after approximately a week, while the shift of the end-point to the adult ran... | 627,218 | [
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Megakaryocytic responses to thrombocytopenia and thrombocytosis in Sl/Sld mice. | Sl/Sld mice maintain normal platelet counts in spite of a reduced number of megakaryocytes, but their megakaryocytes are macrocytic. The present studied were done to analyze platelet turnover in the steady state and thrombocytopoietic responses to perturbations of the platelet count. Platelet production, estimated with... | 627,255 | [
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Calcium and secretin as provocative stimuli in the Zollinger-Ellison syndrome. | The effects of calcium and secretin were studied in 8 patients with the Zollinger-Ellison syndrome and 18 patients with duodenal ulcer disease. Intravenous infusion of calcium gluconate produced marked increases in serum gastrin levels in the patients with Zollinger-Ellison syndrome (4,350 +/- 1,625 pg/mg) and very sli... | 627,316 | [
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Lysosomal bis (monoacylglycero)phosphate of rat liver, its induction by chloroquine and its structure. | Since chloroquine is able to induce phospholipidosis, and in particular formation of bis(monoacylglycero)phosphate [(MAG)2P] in rat liver lysosomes, we tested the influence of the drug on this acidic phospholipid 1) after application of the drug for different periods, 3, 7, 14, 21 and 28 days, and 2) after application ... | 627,403 | [
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0.064... |
Life table analysis of the effectiveness of contraceptive methods using an APL computer program. | An APL computer program has been developed to perform life table analysis without the tedium and error associated with manual computation. Life table analysis is proposed as the standard method of reporting and analysing the effectiveness of contraceptive methods of all types. | 627,419 | [
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[How should mycoses by most effectively treated in dermatological practice?]. | An appropriate antimycetic therapy in the office is based on the following prerequisites: 1. demonstration and identification or at least determination of species of the causative germ, 2. selection of an adequate antimycetic medicament with a) least possible rate of sensitisation, b) greatest possible effectiveness an... | 627,482 | [
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[Problems of hearing aid fitting in elderly adults (author's transl)]. | To provide optimum hearing aid fitting in elderly adults, certain factors are necessary which may affect the frequency response curves of the hearing aids. In cases of presbyacusis, an objective fitting of hearing aids can be based on accurate audiometry (via headphone and loudspeaker) with careful interpretation of te... | 627,488 | [
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G2201-C, a new cyclopentenedione antibiotic, isolated from the fermentation broth of Streptomyces cattleya. | Streptomyces cattleya produced a new cyclopentenedione antibiotic, G2201-C [C6H6O4(I)], which is moderatley active in vitro against Gram-positive bacteria, weakly active against Gram-negative bacteria, and inactive against fungi. G2201-C is toxic to mice. | 627,519 | [
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The management of the foot and ankle in arthrogryposis multiplex congenita. | Sixty-six deformities of the foot and ankle in forty-two patients with arthrogryposis multiplex congenita were reviewd. Pes equinovarus proved particularly difficult to treat as there was a tendency for the deformity to recur because of the thick and rigid capsule. Intracapsular procedures were more successful than tho... | 627,587 | [
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Pseudoaneurysm of the axillary artery following a modified Bristow operation: report of a case and review. | The Bristow operation with its modifications has become a popular therapeutic modality for recurrent subluxation of the humerus. A patient was recently treated for a false aneurysm of the axillary artery six months after such a procedure. The artery had been lacerated by the dislodged fixation screw. The clinical prese... | 627,594 | [
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The effect of oxygen tension and mechanical stress on the outcome of fresh autogenous tissue implants in the canine blood stream. | Fresh autogenous collagenous tissue grafts were implanted in the lumen of the aorta, vena cava, pulmonary artery and vein of thirty dogs. Grafts were studied at varying periods postimplantation. Grafts in the latter three situations were vascularized and absorbed early and were replaced by host fibrous tissue; whereas ... | 627,598 | [
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Colostral constituents including immunoglobulins in the first three milkings postpartum. | Colostral changes in immunoglobulin (IgG), dry matter, ash, total protein, and whey protein were studied over the first three milkings postpartum. Immunoglobulin IgG concentration in colostrum from Holstein cows beginning their first, second, or third lactation was similar. However, older animals had more IgG in colost... | 627,642 | [
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The social behavior of elderly aphasic versus nonaphasic long-term patients. | A study was made of the social consequences of communicative disorders among 51 elderly hospitalized long-term patients. Independent variables used to account for variations in social behavior were: 1) the presence or absence of aphasia, an impairment resulting in varying degrees of loss of verbal recognition, comprehe... | 627,688 | [
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Orienting task effects on EDR and free recall in three age groups. | The present investigation was designed to examine the effects of orienting task-controlled processing on electrodermal response and free recall at two delay intervals for 94 young, 49 young-old (age 55 to 70), and 61 old-old (age 71 to 85) individuals. Subjects were presented with a list of 25 words and performed one o... | 627,707 | [
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A method for testing for synergy with any number of agents. | The standard checkerboard titration for detecting synergy between antibiotics is practicable for combinations of two antibiotics, laborious for combinations of three, and not feasible for combinations of four or more. Nevertheless, methods for testing of combinations of several antibiotics are urgently needed because s... | 627,734 | [
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Cyclic thrombocytopenia induced by a Rickettsia-like agent in dogs. | Hematologic manifestations and the ultrastructure of a platelet-specific microorganism isolated from a dog in Florida were studied. The agent was readily transmitted experimentally to adult dogs by intravenous inoculation with infected blood. Parasitemias and concomitant thrombocytopenias were cyclic in that both recur... | 627,738 | [
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Quantitative binding of penicillin G to tissue homogenates as determined with the preparative ultracentrifuge. | The preparative ultracentrifuge was used to determine quantitative binding of penicillin G to rabbit serum and homogenates of muscle, liver, kidney, bone, lung, spleen, brain, skin, heart, and pancreas. At 10 U/ml rabbit serum bound 46.7% of penicillin G, and all tissues bound 9.0% or less. The ultracentrifuge method w... | 627,749 | [
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Determinants of baroreflex sensitivity in man. | To determine the relationship of BRS to age, ACI, TPRI, and MBP, 61 male subjects, 19 to 65 years of age, whose MBP ranged from 77 to 134 mm Hg, were investigated. Partial correlative analysis was used to hold individual variables constant so that the effect of each on a given BRS relationship could be observed. An ind... | 627,752 | [
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The influence of nitrous oxide anaesthetic on middle-ear fluid. | Nitrous oxide anaesthesia invades the middle-ear cavity, resulting in a positive pressure within this cavity. It has been suggested that the pressure may be sufficient to force open the Eustachian tube and evacuate fluid from the middle ear. This study examined the possible influence of nitrous oxide on middle-ear flui... | 627,766 | [
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Arterio-venous fistula of the ear. | A case of congenital arterio-venous fistula involving the external ear in a 33-year-old female patient is described in this paper. She presented to the hospital with severe haemorrhage from the swelling over the ear necessitating immediate admission into hospital and transfusion of whole blood. The treatment of the cas... | 627,771 | [
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Precocious 'feminization' of rat liver enzymes in the presence of ectopic pituitary tissue. | The presence of ectopic pituitary tissue (derived from an adult rat) in prepubertal male and female rats caused the immature, masculine-type hepatic steroid metabolism to develop into female-type metabolism. It is concluded that the hypothalamus-pituitary system controls the ontogenesis of sex-dependent steroid metabol... | 627,814 | [
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Internal quality control of radioimmunoassays. | A modified cumulative sum technique has been applied to radioimmunoassay quality control data. The method is approximately 50% more efficient in detecting systematic changes in the mean and variance of quality control values for plasma samples than more widely used conventional methods. The salient features of the tech... | 627,815 | [
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Radioimmunoassay of oxytocin. | The evaluation of a radioimmunoassay of oxytocin is described. The method involved careful collection and transportation of blood at 4 degrees C, acidification of the plasma, extraction with Fuller's earth and radioimmunoassay using antisera raised in rabbits immunized against oxytocin conjugated to bovine serum albumi... | 627,820 | [
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... |
Perinatal changes in plasma and adrenal corticosterone and aldosterone concentrations in the mouse. | The concentrations of corticosterone and aldosterone in the plasma and adrenal glands of foetal, newborn and mother mice were estimated during the last 4 days of pregnancy and throughout the perinatal period. The level of corticosterone in the maternal and foetal plasma fell from day 17 of gestation until birth, and th... | 627,822 | [
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0.06271356,
0.1913164,
0.09852684,
0.09107628,
0.06058218,
0.02624065,
-0.0295054,
... |
Neurohypophysial hormonal control of kidney function in the Furopean eel (Anguilla anguilla L.) adapted to sea-water or fresh water. | Low doses of arginine-vasotocin (AVT), isotocin and oxytocin (1 pg-1 ng/kg body weight) were antidiuretic in eels adapted to fresh water but not in those adapted to sea-water. High doses (more than 10 ng/kg) were always diuretic. No effects on tubular water reabsorption were observed and the glomerular filtration rate ... | 627,824 | [
0.1415268,
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0.09889337,
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... |
Complement-mediated killing of schistosomula of Schistosoma mansoni by rat eosinophils in vitro. | Eosinophils from the peritoneal cavity of normal rats, in the presence of fresh normal rat serum (NRS), adhered to schistosomula of Schistosoma mansoni in vitro and killed the majority of parasites within 18 h. The reaction differed from the previously described antibody-mediated eosinophil adherence to schistosomula w... | 627,834 | [
0.2792842,
0.09641731,
0.02441801,
0.01964069,
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0.08341003,
0.3796292,
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-0.2607852,
-... |
Documentation of resident exposure to disease entities. | The medical privilege application forms of hospitals in 15 southern states were examined for the degree of privilege delineation required. Forty-nine percent of the responding hospitals require extensive delineation of privileges. Residents in the Anderson, South Carolina Family Practice Center have instituted a method... | 627,861 | [
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0.2627287,
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0.02848044,
0.1835485,
-0.014088... |
Elevated blood pressures in infants and children. | Blood pressure should be routinely measured in all infants and children. Measurements should be performed with an appropriate size cuff and observed pressures compared to normal values for age. Elevated blood pressure is seen in one to ten percent of children, depending on the age group surveyed and the definition of h... | 627,865 | [
-0.1081497,
0.02687342,
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0.04122444,
0.1052415,
0.06379002,
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Further observations on the incremental stimulus intensity effect and habituation of the human electrodermal response. | Two studies are reported which examined the relative effectiveness of an incremental series of stimulus intensities for reducing electrodermal responsiveness to a test stimulus. In the first study, employing five pairs of male undergraduates matched on electrodermal responsiveness, habituation to a 100 db (re 20muN/m2)... | 627,878 | [
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0.05565108,
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-0.01799875,
0.1596... |
The interpretative validity of the FAM: long-term psychotherapists' ratings of psychiatric inpatients. | Newmark, Conger, and Faschingbauer (1976) found a significant difference between mean ratings of MMPI and FAM (Faschingbauer's Abbreviated MMPI) based interpretations. Since this may have been specific to lack of rater experience, the present study attempted a replication using long-term psychotherapists as raters. The... | 627,986 | [
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0.2248903,
0.1636965,
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0.2525395,
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0.007766399,
-0.3348933,
... |
The laugh of Satan: a study of a familial murderer. | A teenage murderer who killed his mother, his tiny half-brother, and his step-father was studied through the imagery he associated to three different editions of inkblots. These sets included the Rorschach, Behn-Rorschach, and Ka-Ro plates. The data were used to theorize about clues, dynamics, and diagnosis in this ext... | 627,988 | [
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0.4813216,
0.1200087,
0.4505701,
0.1260067,
-0.1672282,
... |
Synthesis and antitumor activity of halogen-substituted 4-(3,3-dimethyl-1-triazeno)quinolines. | Halogenated 4-(3,3-dimethyl-1-triazeno)quinolines were synthesized as potential antitumor agents on the basis of the biochemical pharmacological properties of existing triazenes, their structural-activity relationships, and the high melanin binding of chloroquine and iodoquine in vivo and in vitro. They were synthesize... | 628,002 | [
-0.5138901,
0.103553,
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0.05786346,
0.1246802,
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0.1952665,
0.04932024,
0.2572359,
0.3048662,
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-0.4290679,
-... |
Statistical aspects of extrapolation of dichotomous dose-response data. | A mathematical model based on the hypothesis that carcinogenesis is a multistage process was proposed for the statistical problem of extrapolating the results of bioassay experiments performed at high dose levels of the carcinogenic risk at lower dose levels. This general multistage model had extrapolation characterist... | 628,012 | [
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0.03570261,
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0.04554937,
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0.1111791,
0.228365,
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0.1867646,
0.2778532,
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0.1434709,
0.2724151,
0.1386082,
0.1... |
Isolation from a murine fibrosarcoma of cell lines with enhanced plating efficiency in vitro. | The technique for the isolation of mutants was applied to establish highly clonogenic cells from a fibrosarcoma (FSA) that had an extremely poor growth capacity in vitro (10(-6)--10(-7) of surviving fraction of cells). After consecutive clonings, the surviving fraction of cells increased to 1--5 X 10(-1), whereas that ... | 628,015 | [
0.09947061,
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0.22579,
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0.07921851,
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0.08233193,
0.02928859,
0.03768516,
0.7549627,
0.4159906,
0.1754608,
-0.4050102,
0.... |
Androgenesis as a cause of hydatidiform mole. | Q-band chromosome studies were done in 3 molar conceptuses and their parents, with special attention to six pairs of chromosomes (No. 3, 13--15, 21, and 22) in which polymorphic variants occur frequently. Those six pairs of chromosomes were uniformly homomorphic in moles, whereas at least one of them was heteromorphic ... | 628,023 | [
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0.1104034,
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0.5732013,
0.1867457,
-0.2597392,
-... |
What to do about tic douloureux. | Tic douloureux is a common disease that causes excruciating pain. It is a central pain due to a lesion within the trigeminal nerve or brain stem. The majority of patients with tic douloureux are successfully treated by pharmacotherapy with phenytoin or carbamazepine. Those who fail under medical management should promp... | 628,068 | [
0.08289911,
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-0.3072626,
0.1527652,
-0.4370835,
... |
[Intensive therapy and resuscitation of heart rhythm disorders in myocardial infarct patients and the role of express methods of controlling respiratory function]. | The authors used a complex of express methods to examine respiration and acid-base equilibrium in the unit of intensive care and therapy. Examination by means of these methods during intensive therapy and resuscitation helps in individualizing the therapeutic measures. Various individual disorders of respiration were r... | 628,139 | [
-0.1474326,
0.1336524,
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-0.09375265,
-0.1766542,
0.2240631,
0.4126799,
-0.1542843,
0.195... |
[Lesion of the heart in exotoxic shock]. | The functional condition of the heart in exotoxic shock, the most severe complication in the early toxicogenic form of acute poisoning, was studied in 230 patients in whom shock had developed on the background of severe acute poisoning with fluid caustics, dichloroethane, organophosphoric insecticides or soporifics. Th... | 628,149 | [
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0.02710612,
0.1282851,
0.098117,
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0.1725796,
0.1982828,
-0.2963316,
... |
[A suggestion on the microsurgical treatment of the persistent hyperplastic primary vitreous body (PHPV) (author's transl)]. | Three children suffering from PHPV are described, who originally had been sent to the hospital because of suspected retinoblastoma. Exstirpation of the PHPV after opening the anterior chamber with a corneal cut of 180 degrees under the microscope seems a recommendable treatment. The A. hyaloidea has to be observed care... | 628,183 | [
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0.09777625,
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0.6165882,
0.114162,
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0.1... |
[Studies of the lymph drainage of the eye. 4. Drainage of lymphotropic radioactive tracers (99mTc-Microcolloid) after intravitreal injection (author's transl)]. | In 7 rabbits the drainage of 99mTc-labelled Micro-colloid from the vitreous body of the eye was studied. In vivo measurements with an Anger-type camera were undertaken as well as in vitro measurements after dissection and excision of tissue-probes. From the data followed that indicator's elimination half-life from the ... | 628,188 | [
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0.5949712,
0.3806229,
0.5649427,
0.1856515,
0.1551695,
0... |
A possible mechanism of demyelination of the Syrian hamster with hindleg paralysis. | Electron microscopic studies of the spinal roots and the sciatic nerves of mutant hamsters with hindleg paralysis and of similar age control animals are reported. Fibrillary accumulations, some of which showed a crystalloid organization, were found in the inner loops of the myelin sheath. These changes were severe in t... | 628,201 | [
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0.2339479,
0.2811582,
0.1171301,... |
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