title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Gastroenteritis in London and Jamaica: a clinical and bacteriological study. | The flora of both faeces and small bowel lumen was studied in children with gastroenteritis from London, England, and Kingston, Jamaica. Clinical and laboratory differences between these two groups are described. All bacterial groups in the faeces were greatly altered during gastroenteritis and this particularly affect... | 762,400 | [
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Persistence and pathogenicity of defective Friend spleen focus-forming virus. Decreased transplantability of hemopoietic cells as a marker for preleukemic change. | A latent form of persistent infection can be established in susceptible adult mice inoculated with a preparation of defective Friend spleen focus-forming virus (SFFV) purified free from standard leukemia-inducing helper virus (LLV-F). SFFV persistence was initially observed using an in vivo rescue technique in which SF... | 762,497 | [
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Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes. | The frequencies and absolute numbers of B and T cells in the lymphoid organs of five murine strains (NZB, (NZB X NZW)F1, BXSB, MRL/l, and MRL/n) with SLE-like syndromes were examined. We assessed the frequencies of cells bearing surface Ig, C3d and IgG Fc receptors, and theta-antigen. The sequential expression of Ig is... | 762,500 | [
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Variation of trace element contents in a single human liver. | Multi element analysis of homogenised samples taken from three different areas of a single human liver was performed for 18 elements by proton induced X-ray emission (PIXE). Small (10--20%) but statistically significant variations between the element contents of these areas were found for Cl, K, Ca, Fe, Cu, Zn, Br, Rb ... | 762,503 | [
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Regional impairment of cerebral oxidative metabolism in Parkinson's disease. | Twenty-two patients affected by idiopathic Parkinsonism were studied using the oxygen-15 inhalation technique. The production of labelled metabolic water was found to be decreased in the parietal cerebral cortex, indicating an impairment in oxidative metabolism. This metabolic defect was localised mainly to the parieta... | 762,585 | [
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Serial recording of visual and somatosensory evoked potentials in multiple sclerosis. | Pattern reversal visual evoked potentials (VEP) and short-latency somatosensory evoked potentials (SEP) were recorded at frequent intevals in 7 patients with multiple sclerosis (MS). A persistent increase in latency of VEP was found to accompany evanescent visual symptoms. SEP, whether normal or abnormal, remained stab... | 762,589 | [
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Increased prostaglandin synthesis in childhood diabetes mellitus. | Prostaglandins are synthesized from the fatty acids, linoleic and arachidonic acids, and are associated with increased platelet aggregation as has been found in blood from patients with diabetes mellitus. In the present study blood was obtained from 40 children with diabetes and from 20 control children for measurement... | 762,604 | [
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A BSc level option in biomedical electronics. | 1. The application of electronic instruments in medical diagnosis and therapy is well established. 2. There is a demand for electronic engineers both in industry and in the Health Service at all ranges of educational attainment. 3. It is possible to identify a set of objectives for a first degree course in Biomedical E... | 762,700 | [
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Displaced transverse fracture of the sacrum with nerve root injury: report of a case with successful operative management. | A displaced transverse fracture of the sacrum occurred in a young woman along with lumbar transverse process fractures, displacement suggesting instability in flexion, and nerve root injury, all features common to this injury. Open decompression, reduction, and Harrington rod fixation were successful for this patient, ... | 762,727 | [
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The epidemiology of sudden infant death in upstate New York. | The epidemiology of sudden infant death among infants born during 1974 to mothers residing in upstate New York was studied. Death-certificate characteristics for 190 infants with sudden infant death syndrome (SIDS) are compared with those for 434 infants dying of other causes in the same age range. The overall incidenc... | 762,763 | [
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Screening for sickle cell hemoglobinopathies. | Screening for sickle cell hemoglobin can detect carriers, who can benefit from education and genetic counseling, and can bring about early diagnosis, supportive care, and management for patients with established disease. However, such screening programs should be designed and supervised properly by health professionals... | 762,766 | [
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Hepatitis B virus. Inappropriate reactions to transmission risks. | Ten patients designated as hepatitis B surface antigen (HBsAg) carriers were screened for inappropriate reactions to their disease. Assessment with a 32-item questionnaire showed three carriers to have underreacted to the risks of HBsAg transmission through misunderstandings or denial concerning the disease. One carrie... | 762,815 | [
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Helping hemiparetics to help themselves. Sensory feedback therapy. | Despite the presence of some voluntary movement, the loss of discrete control impairs functioning of the arm and hand in most hemiparetics. Seventy hemiparetic patients, aged 12 to 78 years, were treated and followed up for six months to three years. Electromyographic activity monitored from dysfunctional primary mover... | 762,847 | [
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Comparison of phenytoin determinations in plasma, plasma dialysate and saliva for control of antiepileptic therapy in children. | Phenytoin was determined in plasma or serum, dialysate from plasma or serum and saliva in 45 children and 7 adults by gas chromatography. 200 microliter of plasma were necessary for dialysis. Close correlations were found between phenytoin concentrations in the different media (r greater than or equal to 0.95). Since i... | 762,949 | [
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Morphologic changes in arterial grafts in rabbit ears. | The morphology of auto- and allografted segments of rabbit central ear arteries was studied at various times after grafting. Autografts showed thrombosis only in the immediate postoperative period. Autografts developed intimal thickenings whose cellular elements at all stages were almost exclusively myointimal in type.... | 762,951 | [
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The spectrum of Ebstein's anomaly of the tricuspid valve. | The structure of the tricuspid valve in 14 cases of Ebstein's malformation is described and compared with that in the normal heart. The anomalous hearts showed a spectrum of malformation, varying from minimal displacement of the adjacent parts of the septal and inferior leaflets of the tricuspid valve to presence of an... | 762,960 | [
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Transmural eosinophilic gastroenteritis with ascites. | An atopic patient with recurrent abdominal pain, diarrhea, and ascites was shown to have eosinophilic gastroenteritis. Transmural involvement was inferred from the findings of dense eosinophilic infiltrates in the jejunal mucosa and eosinophilia in the ascitic fluid. An impressive response to steroid treatment occurred... | 762,993 | [
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Unilateral essential hematuria. | At the Mayo Clinic between 1961 and 1975, 54 patients presenting with gross hematuria had "essential hematuria" of unilateral origin diagnosed. Criteria for this diagnosis included normal findings on excretory urogram, unilateral bleeding demonstrated at cystoscopic examination, the absence of infection, and a negative... | 762,999 | [
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[Tracheotomy superior, media and inferior? (author's transl)]. | The traditional classification of tracheotomy in superior, media and inferior is not important. It only is important that the tracheotomy tube is in a tensionless position and does neither irritate the larynx nor the thyreoid gland. This can be obtained by strict conservation of at least the first tracheal ring and by ... | 763,052 | [
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[How to prevent the various neuralgic complaints after operation of maxillary sinus? (author's transl)]. | In order to avoid multiple neuralgic complaints after operations of maxillary sinus the following advice for cautions operative procedures is as follows: 1. A vertical incision in the mucosa of the fossa canine behind the eye-tooth instead of the usual horizontal section. 2. A small dorsolateral fenestration in a part ... | 763,053 | [
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[Possibility of using DST-30 thermoelastoplast in blood transfusion systems]. | Investigating possible application of the DCT-30 thermoelastoplastic shows advantages of some physico-technical properties of this product based on natural caoutchouc and latex by comparison with base-rubber onene. It justifies recommending the former for making injection tubes in the blood transfusion systems. | 763,103 | [
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[Metastases to the bone. Diagnosis, treatment, prognosis (author's transl)]. | The prognosis of cancer patients with metastases to the bone has changed little during the past 10 years despite improvement of diagnostic and therapeutic possibilities. A review of the patients treated at the Surgical Clinic of the Erlangen University between 1969 and 1975 showed that out of 78 patients with metastase... | 763,204 | [
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[Reaction of blood sugar and serum insulin to intravenous longterm treatment with Actovegin. Clinical double-blind study (author's transl)]. | In a randomised double-blind study involving 20 diabetics and 20 patients with normal carbohydrate metabolism, the influence of a 14 days' course of intravenous infusion of protein-free calf blood extract (0.5 ml Actovegin/kg/day) and equivalent amounts of physiological saline solution on blood sugar and serum insulin ... | 763,217 | [
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[Parents of children dialysed at home. Psychological assessment (author's transl)]. | Ten married couples with children undergoing home dialysis were examined by means of different tests used in family interaction diagnosis (Joint Rorschach, SIMFAM, Giessen Test, Bales Scale, Expert Rating). The couples showed a similar cooperation as found in a group of psychologically "ordinary" couples, but emotional... | 763,246 | [
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[Plasma renin activity in diabetic children (author's transl)]. | In 10 healthy and 27 diabetic children aged 11--17 years plasma renin activity was determined in horizontal position (PRA-I) and after stimulation by furosemid and upright position (PRA-II). In diabetic children with or without hypertension and protein-uria, and a normal or only slightly elevated plasma creatinine leve... | 763,247 | [
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Lack of correlation of lymphoblast cell size with presence of T-cell markers or with outcome in childhood acute lymphoblastic leukaemia. | The proportion of pretreatment bone marrow macrolymphoblasts was determined in a total of 93 children with acute lymphoblastic leukaemia (ALL) in order to assess the validity of cell size as a prognostic indicator. A macrolymphoblast (MLb) was defined as having a diameter greater than 12 mum, and patient samples were d... | 764,854 | [
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Conformational changes of transfer RNA. The role of magnesium(II). | Magnesium ions added to tRNAfMET1 selectively stabilize the dihydrouridine helix-tertiary structural region. Low Mg2+ levels have little direct effect on the remaining three cloverleaf helices, but these are prevented from melting independently when their intrinsic Tm is surpassed by the Tm of the tertiary structure. A... | 764,858 | [
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Preparation and properties of the repeating sequence polymers d(A-I-C)n-d(I-C-T)n and d(A-G-C)n-d(G-C-T)n. | The repeating sequence polymer d(A-I-C)n-d(I-C-T)n has been prepared using the chemically synthesized oligomers d(A-G-C)4 and d(C-T-G)4 and the DNA polymerase from Micrococcus luteus. The enzymatically synthesized polymer was used as template for preparation of d(A-G-C)n-d(G-C-T)n. Both deoxyribonucleotide polymers wer... | 764,859 | [
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0.11... |
Mechanism of yeast cytochrome b2 action. II. Steady-state kinetics of oxalate inhibition. | From a careful steady-state kinetic study it is shown that the inhibition of L-lactate oxidation by cytochrome b2 with ferricyanide as acceptor is of the mixed competitive-noncompetitive type, indicating the formation of an active ternary complex between enzyme, substrate, and inhibitor. With a large excess of acceptor... | 764,861 | [
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Fluorescence energy transfer measurements between ligand binding sites of the pyruvate dehydrogenase multienzyme complex. | The interaction of the pyruvate dehydrogenase multienzyme complex from Escherichia coli with 8-anilino-1-naphthalenesulfonate (ANS), pyruvate, and acetyl-CoA has been investigated using equilibrium binding, steady-state fluorescence, and fluorescence lifetime measurements. The fluorescnece of ANS is greatly enhanced wh... | 764,864 | [
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Inactivation by detergents of the proline transport system in membrane vesicles from Escherichia coli and its reactivation by bovine serum albumin. | The proline transport system of membrane vesicles from Escherichia coli was inactivated by a low concentration of detergents such as deoxycholate, dodecyl sulfate and Triton X-100. The addition of a large amount of bovine serum albumin to membrane vesicles which had been treated with one of these detergents resulted in... | 764,873 | [
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Ionophores X537A and A23187. Effects on the permeability of lipid bimolecular membranes to dopamine and calcium. | X537A carries dopamine across lipid bimolecular membranes. The rate of transport increases linearly with the X537A concentration and is independent of an electric field across the membrane. The evidence suggests that the permeating species is a neutral 1:1 complex between dopamine and X537A. A23187 does not transport d... | 764,880 | [
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Median facial malformations and their implications for brain malformations. | For purposes of identifying craniofacial syndromes which predict brain malformations the face can be regarded as developing from 2 sources. The median and paramedian structures derive from the embryonic segment of the face, termed the frontonasal prominence. The lateral structures of the face derive from the branchial ... | 764,897 | [
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[Morphometry of the juxtaglomerular apparatus of allo-transplanted human kidneys]. | Juxtaglomerular appartus of 17 allotransplanted human kidneys was studied by the karyometric method at various periods of existence in the recipient's organism. Kidneys of persons who died of craniocerebral trauma or acute cardiac incompetence served as control. At the early periods (up to 2 months) there was revealed ... | 764,900 | [
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Transmission of hepatitis type B from healthy HBsAg-positive mothers. | Seventeen mothers, all apparently healthy carriers of hepatitis-B surface antigen (HBsAg) during pregnancy, and their children were studied for four to five years to determine the transmission rate of hepatitis-B virus infection. All the mothers had antibody against hepatitis-B core antigen in addition to HBsAg. One of... | 764,911 | [
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Renin concentrations and effects of propranolol and spironolactone in patients with hypertension. | In a crossover study 32 patients with hypertension were randomly allocated to treatment with spironolactone 200 mg/day for two months, propranolol 320 mg/day for two months, and a combination of both drugs at half the dose. Between the treatments placebo was given for two months. Both spironolactone and propranolol low... | 764,929 | [
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Growth of medical laboratory work during 1920-2000. | The volume of work carried out by pathology departments has grown exponentially since they were first opened, and this is likely to continue to the end of the century. Computer diagnosis may modify the process. | 764,939 | [
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Adaptation of the cells of Escherichia coli to the presence of hydroxyurea increases the level of inorganic pyrophosphatase acttivity. | Hydroxyurea, an inhibitor of ribonucleoside diphosphate reductase, completely arrested the net synthesis of DNA for 3-4 h, when it was added in 30 mM concentration to growing cultures of Escherichia coli K12. Thereafter the net synthesis of DNA started again, although slowly, and simultaneously with it the formation of... | 764,988 | [
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A study of multiracial malocclusions. | The prevalance of a number of malocclusion traits was investigated for 1,000 modern British caucasoid, 70 medieval British, 60 Anglo-Saxon, 100 negroid and 100 mongoloid dentitions. Marked contrasts were evident in the sagittal, vertical and transverse occlusal and spacing anomalies between the various samples, with de... | 765,054 | [
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Somatostatinergic neurons in anterior hypothalamus: immunohistochemical localization. | The distribution of somatostatin was studied in the rat with an immunoperoxidase technique and rabbit anti-somatostatin. Somatostatinergic neurons were identified in the preoptic and anterior periventricular hypothalamus between the anterior commissure, optic chiasm, and the anterior portion of the ventromedial nucleus... | 765,116 | [
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The functioning and interrelationships of blood capillaries and lymphatics. | The structure and function of blood capillaries, as related to permeability, depends on tight, close and (in injured vessels) open junctional regions, small vesicles, vacuoles (in injured vessels) and fenestrae. The basement membrane presents a hindrance to the larger macromolecules, at high flow rates, but not to smal... | 765,142 | [
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[The hypermobile skin- and soft-tissue tube in thumb reconstruction]. | Reconstruction of an amputated thumb using a bone graft covered by a tubed skin pedicle gives good results if sufficient vascular supply and sensory innervation is transferred to the reconstructed thumb by a neruovascular island pedicle flap and if the skin and soft tissue tube is fixed well enough to the bone graft. H... | 765,236 | [
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On structural formulas of basic fuchsin and aldehyde-Schiff reaction products. | A variety of structural formulas has been suggested for the basic fuchsin moiety of aldehyde-Schiff reaction products. It was therefore deemed of interest to review the development of these different concepts of dye structure. Formulation of basic fuchsin as an ammonium salt preceded the quinonoid theory; however, chem... | 765,308 | [
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On-line cardiac output by digital computer. | Many devices for fast cardiac output calculations employ special assumptions and departures from the Stewart-Hamilton method. These assumptions and departures can cause substantial errors. This publication describes an on-line computer system for evaluating dye-dilution curves according to the classical Stewart-Hamilto... | 765,318 | [
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Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 6. Synthesis of the deoxyribopolynucleotide segments corresponding to the nucleotide sequence 100-126. | Chemical syntheses of the tridecanucleotide, d(G-C-T-T-C-C-C-G-A-T-A-A-G), the dodecanucleotide, d(G-C-T-C-C-C-T-T-A-T-C-G), the decanucleotide, d(G-G-A-G-C-A-G-G-C-C), the nonanucleotide, d(T-A-C-T-G-G-C-C-T), and the hexanucleotide, d(G-G-A-A-G-C), are described. Together, these syntheses represent the nucleotide seq... | 765,331 | [
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Regulation of carbohydrate uptake and adenylate cyclase activity mediated by the enzymes II of the phosphoenolpyruvate: sugar phosphotransferase system in Escherichia coli. | The uptake of various carbohydrates and the synthesis of adenosine 3':5'-monophosphate (cyclic AMP) are subject to inhibition by sugar substrates of the phosphoenolpyruvate:sugar phosphotransferase system in Escherichia coli. The induced synthesis of the sugar-specific components of the phosphotransferase system was st... | 765,335 | [
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Superoxide dismutase. Reversible removal of manganese and its substitution by cobalt, nickel or zinc. | The maganese-containing superoxide dismutase, from Escherichia coli, lost metal and activity when dialyzed against 20 mM-8-hydroxyquinoline and 2.5 M guanidinium chloride in 5 mM Tris-chloride buffer at pH 7.8. Subsequent dialysis against 0.01 m M McCl2, in this buffer, caused a restoration of manganese and activity. R... | 765,340 | [
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Computer-based modeling in the teaching of steady-state enzyme kinetics. | Equations are derived for the steady-state treatment of enzyme reactions with one type of inhibitor, consisting of one reaction cycle or two connected cycles. Computerized stimulation programs are described which are designed to acquaint the student thoroughly with the behavior of enzyme systems. The user has freedom i... | 765,350 | [
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[Nomographical determination of brain wet weight of small mammals (albino rats) from weight of brain fixed in different ways]. | Some nomograms have been designed, based upon albino rat brains, which are fixated by several liquids (Bouin, Carnoy, formaldehyde, Golgi-Cox according to Ramon-Moliner). These nomograms allow to determine the weight of fresh unfixated brains (HFG) in a simplified manner, if it was possible only to determine the weight... | 765,396 | [
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Current status of luteinizing hormone-releasing hormone in diagnosis and treatment of disorders in reproductive function. | The concept of the hypothalamic regulation of the function of the anterior pituitary was established by experiments involving the interruption of blood supply from the hypothalamus to the pituitary, transplantation of pituitary to sites away frm the hypothalamus and the effects of various lesion and electrical stimulat... | 765,458 | [
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Inhibitors of the luteinizing hormone-releasing hormone based upon modifications in the 2, 3, and 6 positions. | [Leu2,Leu3,D-Ala6]-LH-RH (less than Glu-Leu-Leu-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-[NH2) and [Val2,Leu3,D-Ala6]-LH-RH completely inhibited the release of LH and FSH induced by 0.3 ng/ml of medium of LH-RH on isolated rat pituitaries, at a dosage of 10 mug. [Leu2,Val3,D-Ala6]-LH-RH and [Val2,Val3,D-Ala6]-LH-RH also completel... | 765,459 | [
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0.12... |
Bacterial contamination of skin used as a biological dressing. A potential hazard. | Bacterially contaminated skin used as a biological dressing on burn wounds can cause serious or even lethal infections, three examples of which are cited. Cadaver-skin allografts were frequently found to contain pathogenic bacteria. The frequency of infections due to the use of contaminated skin grafts on open wounds i... | 765,519 | [
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... |
Long-term metaproterenol therapy in asthmatic children. | The bronchodilator efficacy and safety of metaproterenol sulfate were evaluated by double-blind crossover tests against placebo at three intervals during a 90-day treatment period in 50 asthmatic children. One group of 25 patients was continuously treated with metaproterenol syrup, and the other 25 with placebo syrup. ... | 765,528 | [
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[Tissue culture investigations on the distinction between hereditary and sporadic retinoblastoma (author's transl)]. | The growth pattern in tissue culture of cells derived from retinoblastoma is different for all cases with known heredity and most of the cases with unknown heredity. It is concluded that those of the latter, that show a growth pattern that is identical with that of the hereditary cases, represent the hereditary cases i... | 765,605 | [
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[Automatic analysis of electrocardiograph signals in the diagnosis of myocardial infarct]. | At present the work of automatization of the processes of the ECG analysis for diagnosing myocardial infarction with the help of computer technique is going forward on an ever broader scale. For an automatic identification of the focal changes syndrome on the ECG, which in the clinical practice is considered to be tant... | 765,669 | [
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... |
[Effect of cultivation conditions on the electrophoretic spectrum of various dehydrogenases in Saccharomyces cerevisiae]. | The activity and electrophoretic spectrum of glucose-6-phosphate dehydrogenase, alcohol dehydrogenase, and malate dehydrogenase in Saccharomyces cerevisiae 14 depended on the conditions of cultivation, i. e. the sources of carbon and their concentration, the content of nitrogen, and aeration of the medium. A heterogene... | 765,685 | [
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... |
[Antibody differentiation in human toxoplasmosis experiments on model cases (author's transl)]. | Human sera with antibodies against Toxoplasma gondii were investigated-before and after gel filtration (Sephadex G 200)-by IgM-and IgG-specific immunofluorescent reactions as well as well by complement fixation tests.-In sera from patients with "latent" infections IgM-antibodies could not be demonstrated neither by the... | 765,711 | [
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0.3084767,
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Stimulation in trans of synthesis of E. coli gal operon enzymes by lambdoid phages during low catabolite repression. | The infection of E. coli cells with different lambdoïd prophages triggers a stimulation of galactokinase synthesis when cells are grown in a medium giving rise to a mild catabolite repression (tryptone broth) with an inducer of the gal operon (fucose). These results show that during phage infection (or induction) some ... | 765,754 | [
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0.2010573,
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The role of tissue typing in corneal transplantation. | The ABO relationships of 150 corneal transplant recipients and their donors were evaluated as were IgG and IgM isoagglutinins in recipients receiving grafts from ABO-incompatible donors. The HL-A antigens of 43 corneal transplant recipients and their donors were determined as were the cross-matches of donor lymphocytes... | 765,781 | [
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Some remarks on the immunopathology of toxoplasmic uveitis. | Data obtained from prospective studies of congenital toxoplasmosis and from serological examination of patients with uveitis suggest that ocular toxoplasmosis is mostly congenital in origin. It is mainly related to the immunological clearance of residual cysts persisting after a subclinical congenital toxoplasmosis. | 765,785 | [
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Effect of caffeine on recovery from DEB-induced cell inactivation in UV-sensitive mutants of Saccharomyces cerevisiae. | The UV-sensitive yeast mutants rad3 and rad6 are highly sensitive to diepoxybutane (DEB) as compared with the RAD strain. The two mutants show differential response to liquid holding (LH) after exposure to DEB and UV. The survival of rad3 increases markedly after DEB and decreases after UV. Caffeine significantly affec... | 765,799 | [
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Genetic effects of formaldehyde in yeast. I. Influence of the growth stages on killing and recombination. | In random cultures, stationary phase cells of Saccharomyces cerevisiae are more resistant to killing induced by formaldehyde than are exponentially growing cells. It is shown that this compound induces intra- and intergenic recombination in this eucaryotic organism. In synchronized populations the lag and G1 phases dem... | 765,800 | [
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Induction of mitotic recombination with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in Saccharomyces cerevisiae. A comparison between treatment in vitro and in the host-mediated assay. | Two methods, treatment in vitro and the host-mediated assay method, were compared in their ability to demonstrate the induction of MNNG of nitotic recombination in a diploid strain of Saccharomyces cerevisiae. MNNG had a strong activity in vitro but not in the host-mediated assay at the concentrations tested. When the ... | 765,810 | [
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Induction of chronic progressive glomerulonephritis with immunofluorescent "mesangial pattern" in rats. | Morphologic changes of extracapillary and chronic progressive glomerulonephritis with contracted kidneys, resembling those of adult human chronic glomerulonephritis, were induced in rats by a single injection of the purified glycopeptide and Freund's incomplete adjuvant into the hind footpads. The purified glycopeptide... | 765,872 | [
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A simplified method of percutaneous allograft biopsy. | Although the renal allograft represents only a single-functioning kidney, it lends itself readily to biopsy from a percutaneous approach. Previous contraindications to percutaneous biopsy of a single normally situated kidney do not apply to the renal allograft because of its altered extraperitoneal and superficial loca... | 765,876 | [
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0.04099268... |
[A case of primary reticulum cell sarcoma of the brain with uveitis (author's transl)]. | In 1972, Neault and his co-workers reported seven cases of uveitis associated with intracranial reticulum cell sarcoma. Recently we have experienced a similar case for the first time in Japan. A 32-year-old woman registered on March 10, 1971, complaining of blurred vision in the left eye for about two weeks. By ophthal... | 765,882 | [
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0.... |
[Alport's-syndrome: diagnosis, light- and electronmicroscopic findings (author's transl)]. | Alport's syndrome is a hereditary nephropathy with grave prognostic consequences. The occurrence of this disease is probably more frequent than was assumed until now - many cases are not immediately recognized as such. It is possible to make a clinical diagnosis from detailed family histories and through careful examin... | 765,939 | [
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... |
Self-inhibiting action of nortriptylin's antidepressive effect at high plasma levels: a randomized double-blind study controlled by plasma concentrations in patients with endogenous depression. | Below the toxic plasma level of nortriptyline (NT) an upper therapeutic limit has been postulated in patients with endogenous depression. If so the clinical significance is obvious and a double-blind, randomized study was performed in order to solve this problem. Two groups of patients were controlled at different plas... | 766,041 | [
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Preponderance of postsystolic period in the positive inotropic effects of increases in (Ca++). | If the frequency of stimulation of isolated kitten right ventricular papillary muscles is progressively reduced, the size of contractions decreases until a frequency is reached (rested state rate) where further reduction produces no change (rested state contraction, Koch-Weser and Blinks, 1963). At 30 degrees C and 2.2... | 766,127 | [
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0.0004709613,
0.2133097,
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0.03... |
[Treatment of arthrosis with a new non-steroid anti-rheumatic agent (Voltaren). A double blind comparison with indomethacin]. | The new antirheumatic agent diclofenac sodium (Voltaren) has been compared with indometacin with respect to tolerance and effect on osteoarthritic symptoms. In a double blind trial two groups of 30 arthritic patients each received Voltaren and indometacin respectively for 12 weeks. The initial dose for both drugs was 7... | 766,164 | [
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0.1190939,
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0.001000411,... |
[Viewpoints on the pharmacological suppression of immunologic reactivity]. | The pharmacological alteration of immunological reactivity is considered. The immunosuppressive drugs may be classified according to their chemical class and their antigen- or cycle-dependency. A relative specificity towards the lymphoid system is cyclophosphamide. New vistas are opened by the modulation of immunologic... | 766,172 | [
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[Proceedings: Microbiology of endocarditis]. | The classical paper published by Schottmüller in 1903 has shown beyond doubt that blood cultures are a crucial diagnostic procedure for the diagnosis of endocarditis. Positive blood cultures also make it possible to distinguish between bacteremia and endocarditis: in the latter condition the number of organisms per ml ... | 766,174 | [
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... |
[Determination of antibody specificity to a new influenza B virus variant by means of the immunoadsorption test]. | Immunoadsorption test was used for determination of the strainspecificity of antibody to a new antigenic variant of influenza B virus (B/Hong Kong/5/72 and B/Yamagata/1/73) in human sera collected in April, 1973--March, 1974. The new strains were shown to be circulating in Moscow City only late in February and in March... | 766,407 | [
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... |
[The frequency of sex chromatine occurring in cell nuclei of internal organs determined by the smear method (author's transl)]. | The frequency of sex chromatine occurring in cell nuclei of twelve organs from 25 male and female corpses was determined using the smear method. It was found to be about 60% in the case of female, and about 6% in the case of male corpses. | 766,492 | [
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[New serological investigations into O-antigenic relations between Escherichia coli, Salmonella, Arizona and Citrobacter (author's transl)]. | During a systemic investigation into O-antigenic relations within the family Enterobacteriaceae, with special emphasis on serological relationships between O-antigens (or O-groups) of E. coli and various O-groupps of Salmonella, Arizona, and Citrobacter, our tests confirmed some findings previously descried by other au... | 766,500 | [
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... |
Reactivity of lipopolysaccharides from various salmonella SR and R chemotypes Ra-Re mutants with concanavalin A. | Lipopolysaccharides from different R mutants of Salmonella minnesota and Salmonella typhimurium belonging to chemotypes Ra to Re, as well as from three SR mutants of Salmonella typhimurium were selected for a study of their precipitability with Concanavalin A. Predictions as to the outcome of the reaction could be made... | 766,503 | [
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Receptors for T2, T4 and T6 phages in Sh. dysenteriae 7 and other serotypes of Sh. dysenteriae. | The sensitivity of four strains of Sh. dysenteriae and of nine strains representing other serotypes of Sh. dynsenteriae to phages T2, T4 and T6 was examined. Different extracts, prepared from sensitive strains were tested for their capacity of phage inactivation. We found that the receptor substance for phage T2 is loc... | 766,504 | [
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0.1025424,
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0.0935... |
[Comparative study of the antigens of Streptococcus group A. Rport I. Comparative characteristics of the immunologic activity of partially purified M-protien and the cytoplasmic protective antigen]. | Experiments were conducted on mice. A study was made of the protective properties of the cytoplasmic fraction of streptococcus, group A, Type 1 and of an antigen isolated from it by sedimentation with ammonium sulfate, in comparison with M-protein partially purified by the method of Lancefield and Perlman. Cytoplasmic ... | 766,524 | [
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0.2123014,
0.5527451,
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-0.05642... |
[Condition of microflora of the nasopharynx in immunization with live influenza vaccine for oral administration]. | The authors present data concerning the state of the microflora of the nasopharynx in the immunization of adults and schoolchildren with the living influenza vaccine for oral administration. During the vaccinal process there occurred qualitative changes in the microbial pattern of the nasopharynx and a reduction in the... | 766,528 | [
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0.09729078,
0.5296125,
0.3524613,
-0.02226873... |
Study of the suppression of lactation and the influence on blood clotting with bromocriptine (CB 154) (Parlodel): a double blind comparison with diethylstilboestrol. | Inhibition of lactation was studied in 38 puerperal women in a double blind trial to assess the effect of bromocriptine in comparison with diethylstilboestrol (DS). Simultaneously the influence of both compounds on blood clotting was studied, along with a control group of 20 women not receiving any medication. Bromocri... | 766,555 | [
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Three-dimensional reconstruction of the human heart by video technique. | Three-dimensional reconstruction of different plastic phantoms, organic material and beating human heart was achieved by utilizing a standard roentgen-television system. In continuous stabilized fluoroscopy the television images of the object obtained from different projections were digitized in real time and computeri... | 766,569 | [
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... |
Bubbles in samples for blood gas determinations. A potential source of error. | The presence of small gas bubbles in devices used to collect blood gas samples is considered. A gas bubble whose relative volume is 0.5 to 1% or more that of the liquid in the collection device is a potential source of significant error. Relationships describing the possible magnitude of this error are derived and subs... | 766,610 | [
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0.1078595,
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-0.077977... |
Unusual manifestation of tuberculosis: TE fistula. | Fistulas between the tracheobronchial tree and the esophagus (TE fistula) caused by tuberculosis are rare; usually they are associated with readily apparent pulmonary and/or mediastinal infection, and require surgical management. The patient we describe presented with a TE fistula as the only manifestation of active tu... | 766,627 | [
-0.1352446,
-0.2535296,
-0.1036354,
-0.09866203,
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0.01168354,
0.01126369,
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0.01814208,
0.04467297,
0.023737... |
Immunochemical studies on the serotype of Shigella flexneri and its recombinant. | Chemical and serologic analysis of polysaccharides of Shigella flexneri 2b and its recombinant revealed complete defect of the gene responsible for type II specificity as a result of recombination. At the same time, function of the gene in the same locus responsible for 7,8 group specificity was partially inhibited. At... | 766,721 | [
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0.1689322,
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0.2734904,
0.1969785,
0.3146072,
-0.093582... |
[The distribution of B-lymphocytes in lymphoepithelial tissues as well as in tumors of the neck-, nose-, and throat region derived from lymphoreticular and lymphoepithelial tissues (author's transl)]. | B-Lymphocytes carrying IgG-, IgM,- and IgA-surface receptors were estimated by fluorescence microscopy in the palatine tonsil of 50 patients aged 3 to 18 years as well as in 44 patients with various types of malignant lymphoms and lymphoepithelial carcinomas. Hyperplastic tonsillartissue contains large numbers of B-cel... | 766,742 | [
0.07548117,
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0.06192134,
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0.06185338,
-0.03149941,
0.05437852,
0.3717855,
0.5115678,
0.1198656,
-0.194492,
... |
Recent studies on the role of the thymus in early stages of lymphopoiesis and immune differentiation. | The influence of thymus deprivation and thymus restoration was studied: a) on the cycling capacity of colony forming cells (CFU-S) in the bone marrow and b) on the establishment of tolerance in liver radiation chimeras. After neonatal thymectomy a reduction in the number of CFU-S in the bone marrow was observed. This r... | 766,782 | [
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0.2934546,
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0.01489453,
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0.6114542,
0.4445772,
0.09492875,
0.01951631,
... |
A study of inflatable cuffs on endotracheal tubes. Pressures exerted on the trachea. | A simple method of measuring the pressure exerted by the cuff of an endotracheal tube on the trachea is described and has been used to measure the pressures exerted by 16 commercially available cuffs on the wall of a model trachea. The Shiley, Portex soft-seal, Kamen-Wilkinson (Bivona Fome) tubes had the lowest trachea... | 766,796 | [
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-0.4694969,
-0.3307711,
0.06119963,
-0.3268229,
0.1130541... |
A fluidically controlled ventilator for bronchoscopy. | A simple time-cycled device uses an oscillating, fluidic, bistable element to control the high-pressure oxygen, supply to the ejector of a ventilating bronchoscope. Both manual and automatic modes of function are available, and inflation pressure and respiratory rate are controlled. Its construction is simple, the cost... | 766,797 | [
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0.1219564,
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0.2676592,
0.06262364,
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0.08391801,
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0.04052798,
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0.1310385,
0.001867708,
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-0.211474,
0.05738698,
-0.07610591,
-0.3063587,
0.1474942,
-0.02927425,
-0.0027327... |
Alteration of the allosteric properties of aspartate transcarbamoylase by pyridoxylation of the catalytic and regulatory subunits. | Extension modification of aspartate transcarbamoylase from Escherichia coli with pyridoxal 5'-phosphate followed by reduction of the Schiff base with sodium borohydride caused only partial inactivation of the enzyme. Under comparable conditions, virtually complete loss of enzyme activity is obtained with the free catal... | 766,834 | [
-0.03719549,
0.4415803,
0.04227913,
0.260631,
0.07260172,
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0.1989269,
0.08153005,
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-0.18852,
0.1958205,
0.1480935,
0.2549569,
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0.3879756,
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-0.2123653,
-0.2258497,
0.2084005,
0.2485446,
0.1814356,
-0.05859135,
0.13... |
Influence of geometry on control of cell growth. | The assembled evidence suggests that geometry plays an important role in regulation of cell growth, at least at two levels: (1) For non-transformed individual cells in culture, there may be a continuous range of shapes, from spherical all the way to extremely flat or extended, which correlates with increasing prolifera... | 766,836 | [
-0.1376803,
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0.176384,
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0.2077003,
0.1689466,
0.2732511,
0.2127753,
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-0.1743395,
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0.02918286,
-0.2690433,
0.0137175,
-0.1052298,
0.4412972,
0.3895883,
0.2211017,
-0.2675973,
0... |
[The importance of the density of spleen cell suspensions in cultures for development of immune reactions]. | A relationship was revealed between the number of cells in the suspension of the splenic tissue taken for induction of primary immunization of the reaction outside the organism and the number of the plaque-forming cells (PFC) formed by the end of incubation. It was shown that with increase of the cell density in the cu... | 766,853 | [
-0.0119187,
-0.2466683,
0.2217723,
-0.1579764,
0.1953377,
-0.3066652,
-0.01888254,
0.09823889,
-0.1350002,
-0.03469561,
-0.004986946,
0.06565914,
0.02988162,
-0.04712357,
-0.7943546,
-0.2773342,
-0.2366841,
-0.06247514,
0.007052543,
0.7645496,
0.6335257,
0.2810143,
-0.082... |
[A comparative immunofluorescent study of carcino-embryonic antigen in pseudomucinous cystoma of the ovary and adenocarcinoma of the large intestine]. | The indirect method of immunofluorescent analysis was applied to the study of the localization of the carcinoembryonic antigen (CEA) in pseudomucinous cystoma of the ovary and adenocarcinoma of the large intestine. CEA proved to be concentrated in the membranes and the basal part of the epithelial cells both in the pse... | 766,854 | [
0.2187485,
-0.291748,
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0.09881567,
-0.04985662,
-0.1382512,
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0.09330184,
0.06170474,
0.210837,
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0.2185117,
0.2381692,
-0.320437,
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0.01375972,
0.01279467,
0.358487,
-0.176535,
0.01905384,
0... |
[Oxygen transport in shock (author's transl)]. | This review considers functional repercussions of shock state on the different stages of oxygen transport from alveolus to mitochondria. At the pulmonary level, the decrease in perfusion pressure induces disturbances in the distribition of VA/Q ratio, and therefore leads to aerial hypoxaemia. Prolonged ischemia injures... | 766,877 | [
-0.2233613,
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0.1558663,
0.2083895,
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0.2202146,
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0.0672077,
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-0.1517017,
-0.08546861,
0.3721774,
-0.1334027,
0.2570042,
0.04127641,
0.1929854,
... |
Long survival after renal transplantation in man. | The indications for transplantation, complications, management and results in 127 consecutive patients who had received renal transplants between October 1960 and December 1974 are presented. In 2 cases the donor was an identical twin, in 22 a living relative other than a twin, in 2 an unrelated individual in whom neph... | 766,892 | [
-0.2137634,
0.2323736,
-0.3569835,
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0.2428736,
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0.1078301,
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0.04818982,
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-0.0008748724,
0.2598666,
-0.3462342,
0.1295298,
0.22472,
0.5454242,
-0.1844701,
... |
Cardiovascular effects of insulin. | Insulin increased the heart rates of seven diabetics with normal cardiovascular reflexes. This effect, which was not due to hypoglycaemia, was greater in the upright than in the supine position and was produced by as little as one unit given intravenously. This increase in heart rate may be a compensatory response to m... | 766,895 | [
-0.2287347,
-0.02076409,
-0.5878135,
-0.2448774,
0.2470354,
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0.1023559,
0.04492123,
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-0.3826017,
0.09909191,
-0.1867127,
0.01834108,
-0.1575335,
-0.008489205,
0.3... |
Squamous cell carcinoma of the skin and lip in renal homograft recipients. | Forty-four squamous cell carcinomas (SCC) of the skin and lip were observed in 9 of 464 renal homograft recipients. Clinically and histologically the SCC's fell into two groups. Two patients with widespread warts, suggestive of epidermodysplasia verruciformis, showed multiple SCC's predominantly on the upper extremitie... | 766,948 | [
0.0202961,
-0.1571406,
-0.2137151,
-0.1381271,
0.262896,
-0.4953904,
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0.05222578,
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0.02133153,
0.006081813,
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0.08237163,
0.1589708,
-0.07062992,
0.1252795,
0.3588168,
0.4534637,
-0.184503,
0.00736268... |
Febrile neutrophilic dermatosis in acute myelogenous leukemia. | Three patients with acute myelogenous leukemia and adequate granulocyte reserves developed fever and painful indurated erythematous plaques on their extremities and faces. The plaques became studded with vesicles or bullae and occasionally became necrotic. Histologic examination revealed dermal edema, infiltration with... | 766,949 | [
-0.08611457,
-0.06891848,
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0.06050987,
0.1926194,
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0.2199688,
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0.2901966,
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-0.167961,
-0.02741346,
0.104767,
-0.2701002,
0.3062571,
0.02023971,
-0.04491... |
Prevention of Marek's disease: a review. | Marek's disease (MD) is a highly infectious neoplastic condition of chickens caused by a herpesvirus. The virus is cell associated in tumors and in all organs except in the feather follicle where enveloped infectious virions egress from the body. From this source, infection is spread horizontally by the airborne route ... | 766,959 | [
-0.3187721,
-0.4835162,
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0.184461,
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0.06441601,
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0.01749995,
0.02440586,
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0.2949013,
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0.1217177,
0.2857174,
0.2220433,
-0.3130612,
-... |
Mechanical and surgical interventions for the reduction of myocardial ischemia. | To reduce myocardial ischemia effectively, mechanical or surgical interventions must achieve either augmentation in coronary blood flow, a reduction in myocardial oxygen demand, or a combination of both. Coronary bypass graft procedures can achieve an immediate augmentation in coronary blood flow distally through the i... | 767,016 | [
-0.1823736,
0.0974626,
-0.3061154,
-0.1973592,
0.07072538,
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0.04654225,
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-0.06868786,
-0.3400027,
-0.1480963,
0.02528044,
-0.1150263,
-0.05733347,
0.0649... |
Immunotherapy for allergic disease. | Although immunotherapy initially was purely empirical, immunologic studies of treated patients in more recent years have shown several types of responses that might be beneficial to patients. Likewise, double-blind clinical trials have documented some clinical improvement if sufficiently large doses of certain allergen... | 767,045 | [
-0.1503656,
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0.1056841,
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0.02031255,
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-0.1599099,
0.09269223,
-0.2094312,
0.2521293,
-0.06556331,
0.215914,
-0.0754165... |
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