title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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[The symptom hemobilia (author's transl)]. | A 46-year-old woman with a histologically, immunoserologically and biochemically confirmed chronic destructive non-suppurative cholangitis in the stage of incipient primary biliary cirrhosis developed an erosive, hemorrhagic cholangitis of obscure etiology with massive life-threatening bleeding from the biliary tracts.... | 810,696 | [
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[A child is not a small adult (author's transl)]. | Any drug treatment must be examined separately for each age group. Physiological transitional situations such as the lowered hemoglobin value of the neonate or the knock knee and pes valgus of the infant must not be regarded as pathological, any more than nocturnal enuresis beyond the 4th year of life means emotional d... | 810,702 | [
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Radioimmunoassay of bovine parathyroid hormone. | A radioimmunoassay of bovine parathyroid hormone (PTH) was developed, using guinea pig antiserum against bovine PTH and highly purified 125I-labeled bovine PTH. The 125I-labeled PTH which had been purified by antiserum against PTH had higher sensitivity than that purified by the adsorption method with microfine precipi... | 810,731 | [
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Cerebral toxicity of penicillins in relation to their hydrophobic character. | The neurotoxic effects of ticarcillin, methicillin, phenthicillin, oxacillin, cloxacillin and dicloxacillin were studied in the conscious rabbit. During and after intravenous administration of 1.2 and 2.4 g/kg, resp., over 50 min the blood concentrations of the drugs were determined and the neurotoxicity assessed by co... | 810,732 | [
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Effects of iontophoretically-applied prolactin on unit activity of the rat brain. | The effects of prolactin and other hormones applied electrophoretically to 400 neurons in the brain were studied in rats under urethane anesthesia. 51 prolactinactivated neurons were distributed mainly in the nucleus dorsomedialis, the upper part of the nucleus ventromedialis, and the nucleus habenulae. 26 prolactin-in... | 810,735 | [
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The effect of neutralizing agents on aqueous parachlorophenol. | The effect of possible neutralizing agents on aqueous parachlorophenol were studied. Results indicated that saline, EDTAC, dentin, saliva, prolonged light exposure, and thermal extremes do not appreciably affect the antibacterial properties of aqueous parachlorophenol. The presence of blood and necrotic tissue demonstr... | 810,757 | [
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Ribonucleic acid synthesis in Plasmodium knowlesi maintained both in vivo and in vitro. | RNA extracted from purified parasites of Plasmodium knowlesi was fractionated using agarose gel electrophoresis. Preparations from para sites grown both in vivo and in vitro contained species of RNA with sedimentation coefficients of 4-0S, 5-0S, 16-6S, 24-2S, 31-4S, 38-0S and 48-3S. There was less RNA present in parasi... | 810,760 | [
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Residues of organochlorine pesticides and polychlorinated biphenyls and autopsy data for bald eagles, 1971-72. | Thirty-seven bald eagles found sick or dead in 18 States during 1971-72 were analyzed for organochlorine pesticides and polychlorinated biphenyls (PCB's). DDE and PCB's were detected in all bald eagle carcasses; 30 carcasses contained DDD and 28 contained dieldrin. Four eagles contained possibly lethal levels of dieldr... | 810,769 | [
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Thermal denaturation of B. subtilis DNA in H2O and D2O observed by electron microscopy. | In the present work we studied the initial part of thermal denaturation curves of B. subtilis DNA in normal and heavy water, observing, by electron microscopy, the "opening" of DNA as a function of temperature. The results support the hypothesis that D(2)O plays a stabilizing role on strands separation during thermal d... | 810,777 | [
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Classification of diabetic ketoacidosis. | An analysis of 1000 cases of diabetic ketoacidosis has suggested to the authors their classification into four evolutive stages: incipient ketoacidosis (normal pH, decrease of total CO2, between 20--26 mMol/l and of excess bases between -2 and -5 mMol/l), moderate ketoacidosis (pH 7.31-7.35, total CO2, between 15--19.9... | 810,878 | [
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Neisseria gonorrhoeae and neisseria meningitidis: extracellular enzyme cleaves human immunoglobulin A. | The gonococcus and meningococcus, which infect human mucosal surfaces, elaborate a highly specific proteolytic enzyme which cleaves the immunoglobulin A1 subclass of the principal mucosal antibody, immunoglobulin A (IgA). The susceptible Pro-Thr bond lies in a unique region of the IgA heavy chain; the IgA2 subclass, la... | 810,892 | [
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[Effect of dietary proteins on the multiplication of the protozoon Nosema apis Z]. | By counting the spores of protozoon Nosema apis Z. in Bürker's chamber the author was able to find, in 1495 caged bees sacrificed one week after the parasite invasion, from altogether 26 samples of various feeds statistically sifnificant differences of influencing the protozoon development only in sallow pollen. The di... | 810,939 | [
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Histochemical study on systemic amyloid microdeposits with special reference to parathyroid intrafollicular deposits. | This study was carried out in order to define the histochemical behaviour of the substance present in follicles of normal parathyroid glands obtained at routine autopsies. It was noticed that these follicles with typical amyloid staining properties are constantly present in old persons; furthermore the amyloid in quest... | 810,944 | [
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Absence of a circadian rhythm in crypt cell mitotic rate following chemical sympathectomy in rats. | The circadian rhythms in both consumption of food by rats and in the mitotic rate in epithelial cells lining the bases of the crypts of Lieberkühn of the proximal jejunum were studied in normal and in chemically sympathectomised rats. In normal rats both food consumption and crypt cell mitotic rat showed a distinct cir... | 810,959 | [
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Influence of route of administration on metabolism of [14C]nicotine in four species. | 1. The metabolism of [14C]nicotine has been studied in four species of animals, rabbit, rat, cat and squirrel monkey, after administration by different routes. 2. Intravenous injection of 4 mug/kg [14C]nicotine every 60 s for 1 h results in peak blood levels of approximately 100 ng/ml in all species but the rabbit. [14... | 810,976 | [
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[Changes in the kidney in a case of neurofibromatosis (author's transl)]. | In a case of an 18-yr-old girl with generalized neurofibromatosis there was an unilateral hydronephrosis due to polypoid neurofibromas in the ureter and urinary bladder. In the kidney were interstitial neurofibromas, a great number of dysontogenetic adenomas and also neurofibromatosis of the vessels. | 810,993 | [
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[Comparative study of four national disinfectant testing techniques (author's transl)]. | Four methods for the evaluation of the bactericidal property of disinfectants have been compared. These methods are (1) the qualitative suspension test of the directives for the testing of disinfectants of the German Society for Hygiene and Microbiology, (2) the quantitative suspension test of the dutch committee on ph... | 811,005 | [
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[Transfer of organisms during exchange of heat and moisture in air conditioning installations (author's transl)]. | With the exhaust air from ventilation and air conditioning installations escaping into the open, the heat content is also lost which fresh air from outside obtains at considerable expense of energy and technical equipment. The heat content, on the other hand, consists of about equal proportions of sensible heat and lat... | 811,009 | [
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[Occurrence and function of a proteinase inhibitor in the hemolymph of insects]. | The presence of proteinase inhibitor has been proved in the hemolymph of a number of insect species from seven different insect orders. The amount of proteinase inhibitor in the hemolymph significantly increases after injection of inactivated bacteria into the hemocoelom of Galleria mellonella-larvae. Moreover the larv... | 811,027 | [
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[Changes in the ultrastruct of the rat kidney after intoxication with organophosphates (author's transl)]. | The kidneys of female Sprague Dawley rats were examined by electronmicroscopical and histochemical methods after intoxication with O-pinacolyl-methyl-phosphonylfluoride. The same explorations were made with control animals, with animals after hypoxia for 24 h, and starving for 36 h. The epithelial cells of the proximal... | 811,039 | [
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Electron microscopic studies on the aryl-sulphatase activity of the pineal gland. | On applying p-Nitrocatechinsulphate (2-Hydroxy-5-nitrophenylsulphate) as substrate, characteristic positivity was demonstrable in the pineal gland. The reaction was localized to the Golgi system and to the smooth endoplasmic reticulum, producing in them a homogenous, in the primary lysosomes a fine granulated strongly ... | 811,051 | [
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[The presence and isolation of a highly zinc activated acid phosphatase in the rat brain (author's transl)]. | The paper describes an acid phosphatase from rat brain extracts, which is highly activated by zinc acetate. The separation of the different acid phosphatases was performed by gel electrofocusing. After staining with 1-naphthyl phosphate and hexazonium pararosanilin or stabilized diazonium salts in the presence of zinc ... | 811,057 | [
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Cataracta ossea and other intraocular ossifications. A case report and a thirty-year Danish material. | Cataracta ossea is described in a 5-year-old Danish boy, representing a sequal to a unilateral measles-endophthalmitis 3 years earlier. Ossification was not demonstrated elsewhere in the eye. Further, cases of intraocular ossification over a 30-year period were reviewed, based on the files of the Eye Pathology Institut... | 811,078 | [
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Production of gibberellin-like substances by bacteria and fungi isolated from the roots of pine seedlings (Pinus silvestris L.). | The production of gibberellin-like substances by bacteria and fungi was investigated. A considerable number of the microorganisms studied produced these substances (55 and 86% of bacterial and fungal isolates respectively). Most of the organisms tested synthesized biologically active substances located on the chromatog... | 811,087 | [
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Oral nitroglycerin as a prophylactic antianginal drug: clinical, physiologic, and statistical evidence of efficacy based on a three-phase experimental design. | With the use of a three-phase experimental design, the efficacy of oral nitroglycerin has been evaluated in a total of 53 patients with documented angina pectoris due to coronary artery disease. The study were a double-blind, randomized, and cross-over comparison of controlled-release nitroglycerin (2.6 mg. tablets adm... | 811,102 | [
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Long-term parenteral nutrition in the home. | A program to train patients to self-administer total parenteral nutrition solutions at home is described. The method of training, equipment used, results obtained and the role of the pharmacist in this program are discussed. | 811,113 | [
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[Isolation of "Brucella suis" biotype 5 from a bitch, in Madagascar. Validity of the species name "Brucella canis" (author's transl)]. | A Gram-negative organism isolated from a btich, in Madagascar, was examined by bacteriologic, immunologic and metabolic methods, in parallel with cultures representative of the Brucella species. The organism fits well into the genus Brucella on the basis of its growth, biochemical and antigenic characteristics and was ... | 811,148 | [
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[Prolactinemia in primary hypothyroïdism : basal and dynamic studies--signification of galactorrhea associated with myxedema (author's transl)]. | PRL and TSH were measured by radioimmuno-assay in 14 persons wth myxoedema aged 16 to 65 years. Three of them had galactorrhea. In 13 patients the circadian rhythm of PRL was studied, and in 8 patients PRL was measured after TRH administration. All these patients have a high value of serum TSH, with a mean value +/- SE... | 811,155 | [
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Production of aflatoxins B1 and G1 by Aspergillus flavus and Aspergillus parasiticus isolated from market pecans. | One hundred and forty-eight isolates of Aspergillus flavus and A. parasiticus were isolated from 5,608 pecans obtained from Chicago and Georgia markets. The percentage of internal contamination by these species was 7.3% in the Chicago market pecans and 1.7% in those from markets in Georgia. Of the 148 isolates, 93% of ... | 811,163 | [
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... |
Mitral valve replacement with the Hancock stabilized glutaraldehyde valve. Clinical and laboratory evaluation. | From March 1971 through April 1975, one hundred twenty patients underwent mitral valve replacement with a Hancock "stabilized glutaraldehyde process" porcine aortic xenograft. A simultaneous canine experimental series was also carried out. In the clinical series, the early mortality was 8.3%. Actuarial analyses of all ... | 811,195 | [
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0.1... |
Enzymatic repair of UV-irradiated DNA in vitro. | Excision repair of UV-damaged Bacillus subtilis transforming DNA has been carried out by a sequential enzyme system in vitro. Incision adjacent to the pyrimidine dimer in the DNA strand by correndonuclease II-initiated excision of the damage by the 5' in equilibrium 3'-directed exonuclease of the Micrococcus luteus DNA... | 811,206 | [
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0.1... |
Further studies on the effect of aldosterone on electrical resistance of toad bladder. | The fall in transepithelial electrical resistance which accompanies aldosterone stimulation of short-circuit current (Isc) in toad urinary bladder has been studied further to evaluate the possible causal role of this response in hormonal stimulation of Na+ transport. A steady-state change in tissue conductance was foun... | 811,257 | [
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Carotenoid triplet states in reaction centers from Rhodopseudomonas sphaeroides and Rhodospirillum rubrum. | Purified photochemical reaction centers from three strains of Rhodopseudomonas sphaeroides and two of Rhodospirillium rubrum were reduced with Na2S2O4 so as to block their photochemical electron transfer reactions. They then were excited with flashes lasting 5-30 ns. In all cases, absorbance measurements showed that th... | 811,259 | [
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Simultaneous determination of albumin and IgG in serum and CSF: comparison of electro-immunodiffusion and immunonephelometry. | Simultaneous determination of albumin and IgG has been made on 50 sera and 100 CSF of neurological patients by electroimmunodiffusion (EID) and an automated immunonephelometry (AIN). A new type of gel (mixture of carboxymethyl-cellulose and agarose) was used for the determination of IgG by EID. The statistical comparis... | 811,272 | [
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[Changes in the metabolism of the liver and skeletal muscle in parenteral nutrition]. | A study was made of the content of nucleic acids and of the readily-extracted protein in the liver and the skeletal muscle of rats with alloxan diabetes fed parenterally by various hydrolyzates. Administration of various nitrogen media activated nucleic metabolism and thus promoted restoration of protein metabolism. | 811,286 | [
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0.2840043,
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The potential of californium-252 in radiotherapy. Preclinical measurements in physics and radiobiology. | Californium-252 is a man-made radionuclide (half-life 2-65 years) which emits a mixture of neutrons and gamma rays. It is used in radiotherapy as an alternative to radium and extends the potential benefits of neutrons to interstitial and intracavitary applications. Gamma rays account for a variable proportion of the do... | 811,295 | [
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Reduced severity of Rh-haemolytic disease after anti-D immunoglobulin. | A total of 2459 Rh-negative women who received anti-D immunoglobulin after a Rh-positive pregnancy were followed up in at least one subsequent pregnancy. There was a failure of protection rate of 1-6%. Follow-up of 53 subsequent infants of mother in whom protection had failed showed that the infants were less severely ... | 811,308 | [
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... |
The fine structure and the protein composition of gamma phage of Bacillus anthracis. | The fine structure of gamma phage of Bacillus anthracis was studied by electron microscopy with a negative-staining technique. The phage has a hexagonal head and a long tail without a sheath. By electrophoresis on polyacrylamide gels, the proteins of the phage particles are separate into 10 polypeptides with molecular ... | 811,348 | [
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Possible role of nutrients in neoplasia. | The relationship between cancer and diet is supported by epidemiological evidence suggesting that diet is a factor in the development of cancer of various organs including the esophagus, stomach, liver, and large bowel. The role of depressed immunocompetency, especially during critical periods of growth and development... | 811,351 | [
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... |
Comparative ultrastructure of the nerves innervating the muscle of the body of the bladder. | The distribution and structure of the nerves supplying the muscle of the body of the bladder in mammals such as the mouse, guinea-pig, rabbit, cat and dog was compared with that previously demonstrated in the rat. The muscle of the arterioles located between the muscle bundles is innervated by a fine perivascular plexu... | 811,358 | [
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... |
[Role of phosphorylcholine group on inhibiting capacity of lecithin-cholesterol liposomes on streptolysin O]. | Cholesterol inhibition of the hemolytic activity of streptolysin O was used for testing the presence of cholesterol on the surface of lecithin-cholesterol liposomes. Cholesterol as a liposome component is not available for streptolysin inhibition when the molar ratio lecithin-cholesterol greater than 1,25. Incubation o... | 811,390 | [
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0.2064488,
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-0.0130062... |
[Adjuvant and mitogenic effects of detoxified lipopolysaccharides]. | McIntire and al. have observed that a lipopolysaccharide (LPS) extracted from E. coli could be detoxified by succinylation or phtalylation and remained capable of enhancing the immune respose to serum albumins. The data reported here confirm that several LPS preparations after treatment by phtalylation retained their a... | 811,394 | [
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0.4113789,
0.1542062,
-0.1935938,
-0.0350... |
[Neuron projection from the preoptic region and the anterior hypothalamic area towards the mediobasal hypothalamus in the male guinea pig]. | In the male guinea-pig, preoptic and anterior hypothalamic neurons, located in dorsal or ventral position, enter ventrally into the medial basal hypothalamus. | 811,400 | [
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0.080186... |
[Demonstration of a single form of alpha-acetohydroxy acid synthetase in Bacillus cereus T]. | Existence of one form of alpha-acetohydroxyacid synthetase shown by sucrose density gradient ultracentrifugation analysis, and inhibition in vitro by valine studies on the enzyme of Bacillus cereus T. | 811,404 | [
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... |
[Effects of cyclophosphamide on rabies infection in the mouse. Protection confered by serotherapy]. | A very low pathogenic strain of "fixe" rabies (HEP-Flury) gives a rise in mortality in mice immunodepressed with cyclophosphamide. In this experiment model, the rabies antiserum gives efficient protection against the virus. | 811,405 | [
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Biosynthesis of thyrotropin-releasing hormone in organ cultures of the guinea pig median eminence. | Guinea pig median eminence tissue was put into organ culture for periods up to 13 days. The cultured tissue was examined in 3 ways at various ages: a) morphologically, by transmission electron microscopy and light microscopic autoradiography; b) biochemically, by determination of the ability of the cultures to accumula... | 811,456 | [
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(Pro-) insulin biosynthesis and release of newly synthesized (pro-) insulin from isolated islets of rat pancreas in the presence of amino acids and sulphonylureas. | The influence of arginine, lysine, tolbutamide and glibenclamide on (pro-) insulin biosynthesis and release of newly synthesized (pro-) insulin was studied in isolated islets of rat pancreas. Islets were incubated with 3H-leucine and glucose in the presence and absence of the test agents. Proinsulin and insulin of isle... | 811,472 | [
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... |
Free and bound magnesium in fungi and yeasts. | The content of total, bound and osmotically free magnesium was estimated in various fungi and in the yeast Saccharomyces cerevisiae. Total magnesium increases at lower growth rates of Endomyces magnusii and Penicillium chrysogenum 140A as well as during the logarithmic stage of growth of Penicillium chrysogenum Q-176. ... | 811,509 | [
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Enterotoxigenic intestinal bacteria in tropical sprue. IV. Effect of linoleic acid on growth interrelationships of Lactobacillus acidophilus and Klebsiella pneumoniae. | The factors responsible for colonization of the small intestine by enterotoxigenic coliform bacteria in Puerto Ricans with tropical sprue are unknown, but epidemiological observations have suggested that they may be related to an increased dietary intake of long-chain unsaturated fatty acids, particularly linoleic acid... | 811,564 | [
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Modulation of the formation and release of bovine SRS-A in vitro by several anti-anaphylactic drugs. | Slow-reacting substance of anaphylaxis (SRS-A) is released immunologically from bovine lung in vitro. Various drugs known to protect calves and other animals during anaphylaxis were tested to investigate their modulation of the formation and release of SRS-A. The anti-inflammatory drugs, meclofenamate and aspirin, pote... | 811,569 | [
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-... |
The effect of sulfonamides on pain and swelling following removal of ectopic third molars. | A double-blind, placebo-controlled trial was carried out to study the value of cones containing sulfanilamide and sulfathiazole in the healing of third molar sockets. On the seventh postoperative day, 94 patients were examined regarding pain, swelling and the overall effect of the operation. Trials were run to compare ... | 811,573 | [
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... |
Penicillin treatment in oral surgery in patients with coagulation disorders. | There are clinical observations indicating that the frequency of postoperative bleeding after oral surgery in patients with coagulation disorders is reduced by prophylactic antibiotic treatment. To assess this effect, the concentrations of phenoxymethylpenicillin in plasma and saliva were determined during treatment an... | 811,575 | [
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The mechanism of ischemia in anteroposterior compression of the spinal cord. | Intraspinal balloons were used in monkeys to simulate lateral and posterior epidural masses. Posterior masses flatten the cord and occlude the central vasculature while lateral balloons have less effect on central cord perfusion. The significance of these findings in relation to spondylotic myelopathy is discussed. | 811,584 | [
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0.2699326,
0.1847... |
In vitro activity of ticarcillin, carbenicillin and ampicillin against some gram-negative bacilli. | alpha-Carboxy-3-thienylmethyl penicillin (ticarcillin) is a relatively new semisynthetic penicillin which is more active than carbenillin against Pseudomonas aeruginosa. Among the strains tested, those isolated from the respiratory tract showed an increased susceptibility to carbenicillin and ticarcillin. As with carbe... | 811,636 | [
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0.2350805,
0.4172387,
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0.372106,
-... |
Purification and properties of an acidic protein from rat skin. | An acidic protein, extractable in neutral salt solutions from rat skin, was markedly enriched when precipitated by dialysis against 0.5 M acetic acid. After dissolving the precipitate in 0.5 M Tris-HCl buffer, pH 8.0, the protein was disaggregated by the addition of the nonionic detergent Triton X-100 and purified by c... | 811,654 | [
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0.02413881,
0.09199359,
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0.1867801,
-0.100896... |
Comparison of four culture media for the isolation of Mycobacterium tuberculosis: a 2-year study. | Four media, Lowenstein-Jensen, Middlebrook, Petragnani, and ribonucleic acid, were tested for comparative ability to detect Mycobacterium tuberculosis. Specimens used included sputum, urine, tissue, and gastric washings. Three types of comparison were used: (i) comparison derived from randomized specimens; (ii) compari... | 811,686 | [
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Behavioral study of the visual cortex of Galago senegalensis. | An ablation study of the visual cortex of Galago senegalensis was undertaken in the hope of finding clues about the evolution of primate visual cortex. Removal of area 17 resulted in a profound sensory loss manifested by, first, the failure to discriminate between simple patterns; second, a deficit in localizing object... | 811,692 | [
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A two-stage method for cross-linking antibody globulin to ferritin by glutaraldehyde. III. Size and antibody activity of the conjugates. | Immunoferritin conjugates consist of conjugates of different size. They can be separated in 4.5% polyacrylamide gel electrophoresis into at least 4 bands. The amount of the smallest 1:1 conjugate, in which one antibody molecule is linked to one ferritin molecule, is highest in coupling products with low overall yields ... | 811,708 | [
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Use of horseradish peroxidase-labelled antiglobulin for the colorimetric quantitation of erythrocyte antibodies. | Horseradish peroxidase (HRP)-labelled antiglobulin has been used extensively as a histochemical marker. In the method described the stable reaction product formed by using 3,3'-diaminobenzidine (DAB) as the hydrogen donor in the peroxidase reaction was dissolved in a fluoro alcohol, 1,1,1,3,3,3-hexafluoroisopropanol (H... | 811,709 | [
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Isolation of poxvirus from an African Rodent. | A poxvirus was isolated from a wild gerbil (Tatera kempii) caught in northern Dahomey, Africa at the time of an epidemic of human smallpox. Electron microscopic appearance and serologic reactions placed it in the vaccinia subgroup of poxviruses. The isolate differed from ectromelia, rabbitpox, vaccinia, monkeypox, and ... | 811,713 | [
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Spinal cord blood flow as affected by changes in systemic arterial blood pressure. | The authors used the hydrogen clearance method to measure focal spinal cord blood flow (SCBF) in the rhesus monkey over a wide range of mean arterial blood pressures (MAP) in an attempt to test the hypothesis of autoregulation. The MAP was either lowered by bleeding or raised by the intravenous infusion of norepinephri... | 811,767 | [
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Amino acid analogs. III: New syntheses of monomethyl- and monophenylglutamic acids. | Glutamic acid analogs containing 3- and 4-methyl and 2-, 3-, and 4-phenyl substituents were prepared. The 3- and 4-methyl- and 3- and 4-phenylglutamic acids did not inhibit Plasmodium berghei and were nontoxic to the host (mice) at 640 mg/kg. The five analogs in addition to 2-methlglutamic acid were inactive against La... | 811,786 | [
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Changes of particle frequency in freeze-etched erythrocyte membranes after fixation. | The frequency of particles on the membrane fracture faces of freeze-etched human erythrocytes was measured, and the effect of fixation procedures on the particle frequencies was studied. Fresh blood, buffer washed cells and cells fixed in one of the following ways were examined: glutaraldehyde, glutaraldehyde followed ... | 811,805 | [
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Prevalence and distribution of Leucocytozoon smithi and Haemoproteus meleagridis in wild turkeys in South Carolina. | A survey of 76 hunter-killed wild turkeys from all geographic regions in South Carolina during 1972 revealed that 33 of 76 (43%) were infected with Leucocytozoon smithi. Ten turkeys in the Coastal area had multiple infections with both L. smithi and Haemoproteus meleagridis. | 811,815 | [
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Meningococcal disease. Secondary attack rate and chemoprophylaxis in the United States, 1974. | Three hundred twenty-six reported cases of meningococcal disease in the United States from November 1973 through March 1974 were investigated. Three household members became ill with meningococcal disease following onset of the initial case in their household. The secondary attack rate was approximately 3/1,000 househo... | 811,822 | [
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Pancreatic extract lung sensitivity. | Seven patients with respiratory tract sensitivity to powdered pig pancreatic extract were studied with regard to their atropic status and the immunological nature of this sensitivity. The results confirmed the role of allergen specific antibodies to pig pancreatic extract in this sensitization and underlined susceptibi... | 811,964 | [
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[Some properties of carrier strains of Listeria monocytogenes (author's transl)]. | About 60 characteristics have been investigated in 7 hemolyzing and 12 nonhemolyzing strains of L. monocytogenes. From these investigations resulted inter alia that the organism grows well under strictly anaerobic conditions, esculin is split at 45 degrees C,NH3 is produced from peptone, but not from arginin, and H2S c... | 811,965 | [
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Model for the calculation of output for elongated fields at nonstandard distances for a 25-MV betatron and for radiocobalt teletherapy units. | Output-area factors are usually provided only for square fields at one standard distance. To calculate dose for mantle, extended field, total nodal, subtotal body, and total body irradiation, output-area factors are required for a continuous range of shapes and distances. Dose rate measurements have been made for diff... | 811,968 | [
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[Clinico-electroencephalographic observations in epileptic patients during long-term treatment with benzonal]. | Benzonal was given to 52 epileptics. In 50 cases the duration of treatment ranged from 3 months to 7 years (mean 18 months) in doses of 100-500 mg daily, in 2 cases it had to be withdrawn after a short-term treatment because of intolerance. In all cases the drug was given together with other anticonvulsants: hydantoin,... | 812,001 | [
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Antibiotic treatment of secretory otitis media assessed by impedence audiometry. | Impedence audiometry was used to assess the response to treatment with antibiotics of children with secretory otitis media. Only ears with pressure at maximum compliance of less than --150mm water were included. There was a significant improvement with Bactrim, ampicillin and Vibramycin. There was no change without tre... | 812,030 | [
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[Prolactin adenoma. Hypophysectomy during pregnancy]. | The authors report a case of amenorrhoea with galatorrheoa due to a prolactin adenoma secondary to an inducer of ovulation (HMG and HCG) and in which pregnancy occurred. There was sudden progression of the adenoma with formation of a haematoma and the necessity for emergency surgery. In the light of this case, the risk... | 812,055 | [
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Antibody nature of circulating inhibitor of plasma von Willebrand factor. | A circulating plasma inhibitor of the "von Willebrand factor" was observed in a multiply tranfused subject with severe von Willebrand's disease. The platelet-active von Willebrand factor is associated with a plasma protein macromolecular complex that is deficient in the disease. The inhibitor appears to be an IgG antib... | 812,091 | [
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Effect of hypothalamic deafferentation on thyrotropin-releasing hormone levels in rat brain. | The medial basal hypothalamus was isolated from the remainder of the brain of the rat using a Halász knife. Ten to 14 days after the surgical procedure the concentration of thyrotropin-releasing hormone within the island of hypothalamic tissue was 76% lower than in tissue from sham-operated control rats. Thus, much of ... | 812,092 | [
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Contraction of isolated smooth muscle cells by inophore A23187. | Ionophore A23187 causes contraction of smooth muscle cells isolated from the stomach muscularis of Bufo marinus. The peak response is reached within 10 sec of inophore addition and then decays to a lesser, sustained contraction. The initial phase of contraction is maximal at A23187 concentrations greater than 5 X 10(-6... | 812,094 | [
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The influence of intestinal absorption of an amino acid on the subsequent absorption of the same amino acid. | Cysteine absorption was determined in an intestinal segment "in situ" in the rat under general anaesthesia, perfusing the segment twice for 30 minutes, at one hour interval, with the same amount of cysteine dissolved in a 0.85% NaCl solution. At the second perfusion, absorption of the amino acid was about half that at ... | 812,104 | [
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Feeding behavior in the rat with isolated medial hypothalamus. | After complete, unilateral, frontolateral, dorsal isolation of the medial hypothalamus, VMH included, or fornix section above the hypothalamus, total food consumption and diurnal pattern of food intake were followed 85 days postoperatively. It is suggested that the saftety signals are generated not only in VMH nucleus,... | 812,107 | [
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New technics in the operative treatment of scoliosis. | Preoperative correction of scoliotic curves by traction and casting improves the results achieved by operation. Use of the halo-hoop apparatus allows controlled correction when combined with spinal osteotomies. The anterior approach to the spine allows better correction and fusion of the more difficult curves of congen... | 812,182 | [
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Parenteral hyperalimentation and wound healing. | In the first five postoperative days following abdominoperineal resection, two groups of five patients were treated by infusion therapy following two schedules: 11.9 calories per kilogram per day and 0.042 gram of nitrogen per kilogram per day, and 53.8 calories per kilogram per day and 0.244 gram of nitrogen per kilog... | 812,190 | [
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Parenteral nutrition in surgical patients. | Nitrogen balance has been studied under conditions of simple fasting and in the postoperative period on a total of 102 patients. It is much more difficult to restore a positive nitrogen balance in the post-traumatic period, and this can be obtained only with calorie and, above all, amino acid quotas much higher than th... | 812,194 | [
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[Tuber avulsion from the forensic point of view]. | On the basis of 6 case reports regarding avulsions of the tuber of the maxillary bone, the author comments on iatrogenic incidents in general. He deals in particular with the causes and the treatment of tuber avulsion and, finally, with forensiv aspects of this problem. He is of opinion that tuber avulsions are in most... | 812,212 | [
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Effects of different dosages of anticonvulsant drugs on mental performance in patients with chronic epilepsy. | Fifteen epileptic patients had their dose of anticonvulsant drugs changed twice, each time by 30-50 per cent of the initial medication. Before the dose change, the patients were given six especially adapted mental performance tests, which were designed to measure vigilance, reaction time and certain aspects of memory. ... | 812,330 | [
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Immunoglobulins in ranid frogs and tadpoles. | Three distinct immunoglobulins (Igs) have been isolated from serum of Rana catesbeiana frogs. One of these is high in molecular weight and probably corresponds to the IgM-like Igs that have been isolated from a variety of vertebrate species. The other 2 Igs are lower in molecular weight (approximately 7S) and very simi... | 812,343 | [
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-... |
Cardiac manifestations of Fabry's disease. Report of a case with mitral insufficiency and electrocardiographic evidence of myocardial infarction. | The light and electron microscopic findings in the heart of a patient with Fabry's disease are described. The study revealed that all cardiac tissues, including the conducting tissues and the valves, were involved. The latter finding was of particular interest since the patient was known to have mitral insufficiency. T... | 812,352 | [
-0.3373624,
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0.1670021,
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0.2720348,
0.2331395,
-0.092948... |
Control of cost and medical relevance in clinical microbiology. | Government and third-party payers are applying increasing effort to control rising medical laboratory costs by restricting laboratory budgets. This threatens quality in clinical microbiology, where lack of automation has hampered increased productivity. A solution was sought by curtailing work on duplicates and specime... | 812,354 | [
0.002935198,
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0.220556,
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0.005126008,
0.2283524,
0.03165877,
-0.1480182... |
Characterization of beta-D-galactosidase isolated from I-cell disease liver. | The residual beta-D-galactosidase activity (10% of normal) present in an autopsy sample of liver derived from an I-cell patient has been characterized. The pH optima for both I-cell and normal acid 4-methylumbelliferyl beta-D-galactoside activities were 4.35. The adsorption and elution profiles of the I-cell enzyme fro... | 812,360 | [
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0.1458292,
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0.4603342,
0.350944,
0.1721514,
-0.3011382,
-0.1... |
Effectiveness of prophylactic Rh immunosuppression after transfusion with D-positive blood. | In a published investigation 42 D-negative men were transfused with single units of D-positive R1r (CDe/cde) blood to mimic the D-incompatible transfusion accidents occasionally seen in young D-negative women. Twenty-two men received no therapy and 20 were treated with Rh immunoglobulin in a calculated dose of 20 mug o... | 812,364 | [
-0.2784429,
0.03719651,
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0.1990451,
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0.1593405,
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0.3574608,
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0.04599326,
0.0787807,
0.06059439,
0.3938062,
0.4002767,
0.006566063,
... |
A new symdrome of left vocal cord paresis and esophageal diverticulum due to mediastinal fibrosis. | The association of left vocal cord paresis with an esophageal diverticulum pointing to the left at the aorto-bronchial level constitutes a syndrome resulting from mediastinal fibrosis in that region. Demonstration of this type of diverticulum in a case of unexplained left cord paresis establishes mediastinal fibrosis a... | 812,367 | [
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0.08720981,
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0.1683899,
0.03664191,
0.05264205,
... |
Use of arterial infusion of 5-fluorouracil either alone or in combination with supervoltage radiation as a treatment for carcinoma of the prostate and bladder. | Arterial infusion of 5-fluorouracil either alone or in combination with supervoltage radiation achieves a definite objective improvement in patients with estrogen-resistant adenocarcinoma of the prostate. This improvement has been documented by a decrease in tumor size, improvement in intravenous pyelograms, and a chan... | 812,374 | [
-0.01392115,
0.07726094,
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0.2834178,
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0.1655426,
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0.373666,
0.5688391,
0.09145558,
0.1812517,
... |
Metabolism of ascorbic acid and ascorbic-2-sulfate in man and the subhuman primate. | Man does not catabolize ascorbate to CO2, whereas the monkey does catabolize ascorbate and ascorbate sulfate to CO2 when these compounds are given orally. However, it takes the same length of time to produce frank scurvy in both man and the monkey, thus indicating that the comparative storage, rate of use, and mode of ... | 812,409 | [
-0.2352852,
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-0.3018658,
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0.4214439,
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0.07006174,
0.06040019,
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0.2206693,
0.1550401,
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0.2759967,
0.1728504,
0.1463313,
0.332995,
0.01053748,
-0.08... |
Heterogeneity of carcinoembryonic antigen. I. Concanavalin A-reactive and -nonreactive CEA. | The use of Con A-Sepharose affinity chromatography for preparation of CEA from two metastatic liver tumors resulted in a separation of two species of CEA. One is concanavalin A-reactive CEA (CEA-M): the other is Con A-nonreactive CEA (CEA-P). Both CEA-M and CEA-P were glycoproteins and have identical antigenicity. Howe... | 812,411 | [
-0.3174747,
-0.2512366,
-0.3667932,
0.02116348,
0.1467039,
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0.0500067,
0.04376212,
0.4424775,
0.006066797,
0.2809199,
0.2056491,
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0.4698058,
0.1333457,
-0.06015997,
-0.1056586,
-0.2128685,
... |
Lupus-scleroderma syndrome induced by ethosuximide. | Features of both systemic lupus erythematosus and scleroderma developed in a young Chinese girl while on multiple anticonvulsant therapy. These were reversed after withdrawal of the drugs. Readministration of ethosuximide for control of epilepsy caused a relapse with predominant sclerodermatous features. These clinical... | 812,426 | [
0.06976513,
0.2684952,
0.09466064,
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0.3552042,
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0.1628487,
0.03151001,
0.2123527,
0.1009064,
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0.2251367,
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0.1548003,
0.03301323,
-0.03012808,
-0.189952,
0.1372528,
-0.2050815,
0.01... |
Tritiated methylmercury in the brain of squirrel monkeys. | Tritiated methylmercuty hydroxide (MeHgOH) with a specific activity of 306 curies/mol was synthesized by a Grignard reagent from tritiated methyl iodide with a yield of 70%. Tritiated MeHg was given to squirrel monkeys by stomach tube in weekly doses of 0.8 mg/kg. The animals were killed after one dose or six doses. Th... | 812,429 | [
-0.1372467,
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-0.1098939,
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0.3382611,
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0.2457925,
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0.4366743,
0.01138191,
0.3080979,
0.2528943,
0.4531277,
0.3487291,
-0... |
[Electrophysiological study of 2 cases of ventricular pre-excitation compatible with the presence of Mahaim's fibers]. | Report of two cases of ventricular pre-excitation in which the presence of Mahaim's fibres was suggested by the electro-physiological studies. In both cases, the short-circuit of the His bundle was responsible for the abnormally short HV interval. In a patient, atrial acceleration induced an increase of rh at first, re... | 812,439 | [
-0.3966974,
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0.02118068,
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0.03115862,
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-0.3394603,
0.174238,
0.2073898,
-0.3482742,
0.3244492,
0.0116213,
0.06251869,
... |
[Chronic respiratory insufficiency. Incidence in the results of surgical valvular replacement]. | Out of 400 files of patients who underwent valvar correction between 1968 and 1974 under extra corporeal circulation by the thoracic route through median sternotomy 180 were kept for this study. All these 180 patients had a complete functional spirometric examination before operation, analysed in correlation with their... | 812,442 | [
-0.02677568,
-0.130635,
-0.03954538,
-0.1421454,
-0.0199711,
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0.05944927,
0.1755956,
0.3278695,
0.03955287,
0.04742721,
0.009427764,
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-0.4530427,
0.09974957,
0.2150757,
0.1564263,
0.2657391,
0.2303245,
0.03550277,
... |
Comparative immunochemical studies of primate hemoglobins. | The antigenic properties of a number of chromatographically purified primate hemoglobins were compared to those of normal human hemoglobin using a sensitive radioimmunochemical procedure. The degree of inhibition of the antigen-antibody reaction with heterologous hemoglobins appeared to be related to the structural sim... | 812,480 | [
-0.0007569376,
-0.001873707,
-0.3192025,
0.0907316,
0.08138871,
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0.1023482,
0.1152575,
0.08305933,
0.09930646,
0.05203696,
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-0.4233513,
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0.04990321,
0.1923494,
0.2560475,
0.2369086,
0.2155327,
-0.1691483... |
Creatine kinase isoenzymes in baboon tissues and organs. | We determined the activity of the isoenzymes of creatine kinase in homogenates of fresh tissues from six baboons. Twenty-six tissues were removed from each baboon and the isoenzymes in them were separated by chromatography on diethylaminoethyl-Sephadex A-50. Total activity was greatest in skeletal muscle (2600 U/g wet ... | 812,617 | [
-0.1027238,
0.06950402,
-0.1337727,
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0.01042816,
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0.01114808,
0.2912453,
0.1648693,
0.0694464,
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0.1805712,
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0.2314851,
0.02502776,
0.2148178,
-0.04514915,
-0.1016747,
... |
Determination of the primary structure of a mouse IgG2a immunoglobulin. Amino-acid sequence of the H4 cyanogen-bromide fragment. | The complete amino acid sequence of CNBr fragment H4 of the murine immunoglobulin MOPC 173 (IgG2a,chi) has been determined, thus completing the sequence determination of the entire heavy chain. The H4 fragment contains 150 residues, and extends from residue 105 to residue 254 of the heavy chain, which appears thus to b... | 812,695 | [
0.04423124,
0.07745444,
-0.2082034,
0.03347509,
0.2816129,
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0.1955483,
0.2855413,
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0.1023351,
0.1691355,
0.1965599,
0.1784899,
0.1080924,
-0.01546515,
-0.28... |
Organization of the visual cortex: comparative anatomical and behavioral studies. | In all mammals there are two parallel visual pathways ascending to the cortex: the geniculostriate system and the tectopulvinar system. However, there is a difference among mammals in the locus and extent of the cortical target of the tectopulvinar path. In several diverse species such as squirrel and tree shrew the co... | 812,734 | [
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0.196294,
0.09859057,
0.07206476,
0.01104294,
0.4235587,
0.06283773... |
[Double cholinergic and adrenergic regulation of cerebral blood flow]. | Cerebral vascular tonus was measurably influenced by both alpha or beta adrenergic blockade and by inhibition of cerebrovascular acetylcholine or acetylcholinesterase. Cerebral autoregulatory response was significantly affected by intravenous injection of PBZ, intravertabral and intravenous injection of PPL and intrave... | 812,735 | [
0.3441668,
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-0.09100633,
-0.2302484,
0.05758712,
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0.1387157,
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0.169768,
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0.2648855,
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0.4180401,
0.1675813,
0.1362877,
0.1943185,
... |
Further data on HBs subtypes: geographical distribution. | 1123 HBs antigens from silent carriers of different parts of Europe, Africa and Asia were subtyped and classed in the eight categories previously described: a1y(w1), a2yl(w2), a2(3)y(w3), a3y(w4), ayr, a2ld(w2), a3d(w4) and adr: We have showed that w can be subdivided into the system of a subdeterminants, but for the p... | 812,743 | [
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0.3093155,
-0.1876634,
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0.01453664,
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0.2050354,
0.3072873,
0.1288538,
0.09181608,
0.158275,
0.06660246,
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-0.09720589,
0.1693933,
0.0829474,
0.449997,
0.2953404,
-0.232317,
0.157... |
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