title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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[Bacteriostatic and bacteriacidal activity of hydroxy-9 ellipticine in vitro]. | 9-Hydroxy-ellipticine shows a clear effect against bacterial development. This effect depends essentially upon the bacterial species. Two groups can be differentiated: Group I with resisting species composed by negative Gram Bacilli (Enterobacteria and Pseudomonas); Group II with sensitive species formed by Coccus, pos... | 807,356 | [
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[Trehalose, the principle disaccharide of wine]. | By gas chromatography of trimethylsilylated derivatives of sugars, trehalose has been shown to be the main disaccharide in wines; its amount can reach 600 mg/l. Other disaccharides identified (sucrose, isomaltose, lactose and turanose) are present in small amounts, seldom above 50 mg/l, sometimes below 5 mg/l. Traces o... | 807,380 | [
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[Immunofluorescence study of the migration of adenovirus 5 in HeLa cell cytoplasm during the penetration phase]. | Using the indirect immunofluorescence technique in presence of anti-adenovirus-5 antibody, fluorescent spots were observed two hours after adsorption at 4 degrees C onto HeLa cells on the surface of the cells. The spots subsequently became intracytoplasmic and persisted about 7 to 8 h. Intense fluorescence was furthe... | 807,382 | [
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[Synchronization of electromyographic and cinematographic recordings. Applications to vertebrate biomechanics]. | Synchronizing each frame of the cinema of a moving animal with the corresponding EMG of some muscles permits a precise interpretation of the variations of the electric potentials in that muscle with each phase of the movement. e.g. in the rabbit, three bundles of the masseter muscle function independently during the ma... | 807,384 | [
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[Incorporation of radioactive leucine into lizard epididymis proteins. Study during the sexual cycle and after injection of testosterone to untreated or castrated animals]. | Lizard epididymis activity during the reproductive cycle and after testosterone administration results in a marked increase of radioactive leucine incorporation in vivo and in vitro. The electrophoretic distribution of soluble proteins shows different peaks of radioactivity. Comparison between histological response and... | 807,411 | [
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A comparative study of the estimation of calcium in serum. | Five generally applied methods for the estimation of calcium in serum were compared as to their precision, accuracy, speed and productivity. The influence of storage at 4 degrees C and 20 degrees C and of a number of possible interfering factors were also investigated. As a result the continuous flow method with acid d... | 807,437 | [
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Systematic determination of the serum phenytoin level as an aid in the management of children with epilepsy. | The results from systematic determinations of the serum level of phenytoin in 121 epileptic children are reported. The range 12-25 mg/l is effective in most of the children, responding at all to phenytoin, and causes few and minimal side effects. Practically all children with pure grand mal epilepsy could be kept seizu... | 807,479 | [
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[Clinical studies on regulatory system of thyroid hormone secretion and serum triiodothyronine. Part. I. Solid-state radioimmunoassy for human serum TSH and its clinical application (author's transl)]. | A solid-state RIA method using a plastic microtiter plate for human TSH was developed: 1) The choice of carrier protein for standard TSH was critical in this method and pooled sera from untreated Graves patients was found to be suitable for this purpose. The mean lowest detectable TSH level was 0.2 muU/assay, which was... | 807,487 | [
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Colorado: The impact of redeployment of funds on a model state hospital. | The development of the Fort Logan Mental Health Center, which opened in Denver in 1961, was strongly influenced by recommendations of the Joint Commission on Mental Illness and Health. It becomes an innovative, award-winning facility for state-funded, long-term care of patients with the major mental illnesses. Within t... | 807,513 | [
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Population and family studies on carbonic anhydrase II polymorphism in Gambia, West Africa. | 614 individuals from the village of Keneba in Gambia (West Africa) have been typed for red cell Carbonic Anhydrase II using cellulose acetate electrophoresis followed by detection of the enzyme with the fluorogenic substrate fluorescein diacetate. Three phenotypes were found; 479 CAII 1 (80.94%), 107 CAII 2-1 (17.43%)... | 807,516 | [
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Simple and effective method for selecting protein A-dificient mutants by consedimentation with sensitized sheep erythrocytes. | An effective slection method for protein A-deficient mutants was devised by means of cosedimentation with sensitized sheep erythrocytes and anti-protein A serum agar plates. Hitherto, two types of mutants have been successfully isolated by this method. One was deficient in both cell-bound protein A and soluble protein ... | 807,521 | [
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Phagocytosis and intracellular killing of Staphylococcus aureus by normal mouse peritoneal macrophages. | Although Staphylococcus aureus is incapable of intracellular multiplication in cultured mouse peritoneal macrophages, it is killed at a much slower rate than the avirulent Staphylococcus epidermidis. In addition to the presence of capsular material which inhibits phagocytosis of specific strains of S. aureus, the data ... | 807,524 | [
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Biochemical screening for mucopolysaccharidosis, mucolipidosis and oligosaccharidosis. | A reliable methodology has been devised for the screening of mucopolysaccharidosis, mucolipidosis and oligosaccharidosis. 140 individual cases have been studied; this convinced us of the diagnostic value of this screening-program. | 807,540 | [
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Transformation of Bacillus subtilis: transforming ability of deoxyribonucleic acid in lysates of L-forms or protoplasts. | The transformation of Bacillus subtilis by homologous deoxyribonucleic acid (DNA) made available by gently lysing a stable L-form or protoplast suspension was 3 to 10-fold more efficient than DNA isolated by conventional procedures. This increased transformation was not influenced by digestion with pronase, trypsin, or... | 807,561 | [
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Synthesis and degradation of fructose diphosphate aldolase isoenzymes in avian brain. | The intraccellular proteins of animal cells are continuously turning over; therefore, the concentration of a given protein is regulated both at the level of protein synthesis and at the level of protein degradation. Studies on the relative rates of turnover of isoenzymes, such as those of aldolase and lactate dehydroge... | 807,577 | [
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Biosynthesis of heparin. Studies on the microsomal sulfation process. | Nonsulfated, partially N-deacetylated, 14C-labeled polysaccharide was formed by incubation of a mouse mastocytoma microsomal fraction with UDP-[14C]glucuronic acid and UDP-N-acetylglucosamine. After 60 min at 37 degrees the incorporation of radioactivity was interrupted, and sulfation was initiated, by the addition of ... | 807,579 | [
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Amino acid sequence of a vitamin K-dependent Ca2+-binding peptide from bovine prothrombin. | The amino acid sequence of a 31-residue peptide from bovine prothrombin has been determined. This peptide has been shown to contain the vitamin K-dependent modification required for Ca2+ binding (Nelsestuen, G. L., and Suttie, J. W. (1973) Proc. Natl. Acad. Sci. U. S. A. 70, 3366-3370) and the modified amino acid, gamm... | 807,581 | [
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Storage of blood and the mean corpuscular volume. | The mean corpuscular volume (MCV) of blood after storage for up to 24 days under various temperature conditions in ethylene diamine tetracetic acid, acid citrate dextrose, citrate phosphate dextrose, and Alsever's solution was measured using the Coulter S. Storage of blood overnight at 23 degrees centigrade increased t... | 807,602 | [
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Transtracheal aspiration studies in asthmatic patients in relapse with "infective" asthma and in subjects without respiratory disease. | Exacerbations of bronchial asthma that cannot be accounted for by allergic reactions have sometimes been called "infective" asthma. The validity of this designation was tested by study of transtracheal aspirates (TTA) obtained from 27 asthmatic patients in relapse who had findings suggestive of respiratory infection an... | 807,610 | [
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Immunologic hyporesponsiveness in man to group C meningococcal polysaccharide. | By using a hemagglutination-inhibition assay, certain lots of purified group A meningococcal polysaccharide vaccines were found to contain trace amounts of group C polysaccharide (0.032 to 0.128%). Young adult human volunteers inoculated with these vaccines showed a very poor group C serum anti-polysaccharide antibody ... | 807,629 | [
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Differential susceptibility of rabbit sIgA subclasses to trypsin cleavage: characterization of the fragments obtained from the g subclass. | Rabbit secretory IgA (sIgA) was digested with trypsin at 37 degrees C for 30 min and four fractions were isolated by gel filtration. These fragments were characterized by ultracentrifugation, and by their antigenic properties as undigested sIgA, Fab and Fe (Two Fc fragments differing in their content of secretory compo... | 807,638 | [
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Specific detection and semiquantitation of micro-organisms in tissue by nucleic acidhybridization. I. Characterization of the method and application to model systems. | On the basis of circumstantial evidence, a number of human diseases have been postulated to result from the presence of occult infection. To investigate this problem amethod of specifically detecting and semiquantitaing trace quantities of bacterial DNA in infected tissue has been devised. It is based on RNA-DNA hybr... | 807,659 | [
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Nonenzymatic conversion of human hexosaminidase A. | Incubation of purified hexosaminidase A with merthiolate, parahydroxymercuribenzoic acid, or silver ions resulted in the formation of an enzyme which was identical, in all respects tested, with hexosaminidase B. Its electrophoretic mobility was identical to hexasaminidase B at three different pH levels. Its chromatogra... | 807,661 | [
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Inhibition of supraeschar and subeschar Pseudomonas infection by silver sulfadiazine dry foam. | The results of an in vivo evaluation of silver sulfadiazine dry foam are described. Using burned guinea pigs infected with Pseudomonas aeruginosa, silver sulfadiazine was applied every 12hr as the dry foam or ointment. After 72 hr of therapy with the medicated dry foam, only one of the 15 burns remained infected while ... | 807,702 | [
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Further electrophoretic characterization of strains of Tetrahymena pyriformis. | Mobility patterns of 5 isoenzymes in strains of Tetrahymena pyriformis were demonstrated using polyacrylamide disc gel electrophoresis. Six stock strains were compared in these patterns to 4 strains representative of each of the previously described 4 major "phenotypic sets." Stock strains segregated into predicted "ph... | 807,715 | [
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Listeria monocytogenes isolated from wapiti (Cervus canadensis roosevelti). | Serotypes 1 and 4 Listeria monocytogenes were isolated from 14 of 72 wapiti among four of five herds studied in northwestern California. More isolations of Listeria were made during the summer months than during the other months of the study from one of the herds. The pathogenicity of the strains varied with their abil... | 807,750 | [
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[Monomeric igM in acute and chronic liver diseases (author's transl)]. | Monomeric IgM could be found rather frequently in acute hepatitis and chronic aggressive hepatitis and occasionally also in chronic persistent hepatitis. Earlier it was reported in lympho-proliferative-, autoimmune diseases, some infectious diseases and in cirrhosis of the liver. The occurence of monomeric IgM in chron... | 807,770 | [
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The steepness of the dose response curve both for tumor cure and normal tissue injury. | At the Christie Hospital in Manchester, 4 MeV radiation was introduced in 1955. In consequence of a lack of knowledge of absolute dose definition and R.B.E. factor, patients were treated over a range of dosage. Three hundred fourteen patients with laryngeal cancer, treated over a time interval of three weeks, received ... | 807,783 | [
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0.2412105,
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0.03345736,
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0.06067524,
0.2352813,
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0.1016232,
0.1339316,
0.02238372,
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0.1009498,
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0.1216026,
0.4084037,
0.4905726,
0.3294242,
0.0459015,
0... |
[Criteria for the system selection in medicine (author's transl)]. | The selection of an electronic data processing system for use in the medical field is in many cases complicated by the fact that the tasks have not yet been defined accurately in detail. Therefore, the technical system planning may only be carried out on the basis of an organization study which, among other things, is ... | 807,805 | [
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0.1272026,
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0.2805341,
0.373756,
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0.... |
[Parathormone determination with synthetic human parathormone 1-34 (PTH) (author's transl)]. | Using synthetic human parathormone 1-34, a radioimmunological method for measuring this hormone fragment was developed which, as the amino-terminal PTH assay, permits the measurement of the concentration gradient in the neighborhood of OTH-secreting tumors. The use of preoperative location diagnosis in primary hyperpar... | 807,827 | [
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0.368992,
0.5330294,
0.2425315,
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0.01... |
[Meniscopathy as occupational disease (author's transl)]. | Meniscopathy develops through internal causes alone without any external influence. Work such as that of a miner underground, which is associated with particular strain on the knee joint may aggravate this disorder. If such work has been carried out for at least 3 years, an occupational disease is to be assumed. If the... | 807,833 | [
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0.02437792,
0.1... |
[Critical assessment of angiographic findings in malignant tumors of the extremities (author's transl)]. | Five selected cases out of a total of 36 patients who had been investigated by angiography for tumors of the extremities are demonstrated in order to show the difficulties which can arise in the interpretation of their angiograms. In the subsequent discussion, the classical criteria of Dos Santos for malignant tumors a... | 807,837 | [
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0.06939445,
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0.4389957,
0.3214897,
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The ultrastructure of Candida krusei. | Various methods of chemical fixation and freeze-drying of Candida krusei were compared to determine the most appropriate method for the ultrastructural investigation of the thick walled organisms of this genus. Freeze-drying without chemical fixation was of little value because of insufficient variation in electron den... | 807,847 | [
0.01509216,
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0.36... |
[Value of EEG studies in the differential diagnosis of seizures in children]. | The importance of various morphotic elements of EEG tracings in the diagnosis of seizures in children is discussed with particular reference to seizures connected with fever. The common neurophysiological mechanism of epileptic discharges in various epileptic seizures in children and adults is stressed calling attentio... | 807,865 | [
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0.241221,
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Band keratopathy due to hyperparathyroidism. | A patient with hyperparathyroidism and corneal calcifications is reported. The calcifications appeared following phosphate treatment and persisted for 31/2 years, despite local instillation of EDTA. Local application of EDTA after mechanical removal of the corneal epithelium completely eliminated the corneal deposits. | 807,896 | [
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0.1266425,
0.4235553,
0.04912237,
0.18... |
F antigen. II. Chemical and physical properties. | Physical and chemical properties of the liver-specific F antigen suggested a model for the labile quarternary structure of the protein. The native molecule showed a size slightly larger than 60,000 dalton (d), which was reduced to about 40,000 d under acidic conditions. Breaking of hydrogen bonds by chaotropic treatmen... | 807,901 | [
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0.07947407,
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... |
Herd incidence of bovine mastitis in four Danish dairy. districts II. Evaluation of the effect of the mastitis control scheme. | Bacteriological and cytological examinations have been carried out on samples from 6,808 cows belonging to 339 herds in four Danish dairy districts. After a discussion of differences between the districts as regards intensivity of mastitis control, public health surveillance, etc., definitions are given of certain term... | 807,908 | [
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0.2925779,
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0.6895213,
0.04807707... |
"Core" glycolipid of enterobacteriaceae: immunofluorescent detection of antigen and antibody. | The Re chemotype mutant of Salmonella minnesota R595 has a cell-wall glycolipid composed principally of 2-keto, 3 deoxyoctonate and Lipid A, which is an antigen widely shared by Enterobacteriaceae. High-titered antiserum against this antigen can be conjugated with fluorescein isothiocyanate for direct detection of this... | 807,915 | [
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Hapten-immunological studies on mescaline. | Antibodies with mescaline binding specificity were raised in rabbits by immunization with conjugates of bovine serum albumin with mescaline or its analogue 3,4,5-trimethoxyphenylacetic acid. Immunized rats were given mescaline and their behavior was compared to that of non-immunized controls. | 807,928 | [
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Dosimetry of Hodgkin's disease therapy using a 4 MV linear accelerator. | This report describes a detailed analysis of the dosimetry of the mantle technique for the therapy of Hodgkin's disease when a 4 MV linear accelerator (Varian) is utilized. Doses were determined in a Rando phantom and in vivo using several methods of dosimetry. Significant dose variations, exacerbated by the lead flatt... | 807,947 | [
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Is there any association between elevated serum prolactin level and mammary adenocarcinoma induced by 7,12-dimethylbenz(alpha)anthracene. | The association between mammary carcinogenesis induced by 7,12-dimethylbenz(alpha)anthracene (DMBA) in the rat, the influence by manipulations of its hepatic metabolism and the secretion of prolactin has been investigated. Various test compounds: coumarin, 4-methylcoumarin, phenobarbital and CCl4 all elevated serum pro... | 807,960 | [
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... |
The role of plasma amino acids in hepatic encephalopathy. | The dog with an end-to-side portacaval shunt has a plasma amino acid pattern similar to that in man with chronic liver disease and encephalopathy. When dogs with end-to-side portacaval shunts manifested symptoms of hepatic encephalopathy, superior caval catheters were placed and one of three solutions was infused. Wher... | 807,982 | [
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[Swine Vesicular Disease. A Review (author's transl)]. | The article gives a comprehensive review on swine vesicular disease (SVD). The properties of the virus, symptoms, diagnosis, epizoötiology and control of the disease are described. The clinical appearance is illustrated by photographs from experimental infections. The differences in the epizoötiology of SVD and foot-an... | 807,989 | [
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Todd's paralysis: A cerebrovascular phenomenon? | Postictal transient focal neurological deficits, i.e., Todd's paralysis, at times are correlated with early veins and/or vascular stain angiographically. Radionuclide gamma camera images show that they also may be accompanied by a relative flow hyperperfusion and a cortical rim static image uptake. Using these observat... | 807,998 | [
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0.1104171,
... |
[Effect of fatigue in slaugher rabbits on the quality of their meat]. | The organoleptic properties, bacteriological picture, and some chemical characteristics of meat (M longissimus dorsi) were compared in slaughter rabbits exposed to physical exertion and rabbits used for control. Some organoleptic deviations did occur, particularly in meat colour; however, they were very small, and sto... | 808,004 | [
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[Effect of various solvents and temperatures on the survival of boar spermatozoa]. | The second fraction of boar ejaculate was thinned with six differently treated diluents of the Beltsville 3 type and with four diluents of the Ejadyl type containing Chelaton 3. All thinned sperm was kept at the temperature of +4 degrees C and +16 degrees C for 72 hours. At both test temperatures throughout the period ... | 808,016 | [
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Plasma prolactin levels after TRH and chlorpromazine in normal subjects and patients with impaired pituitary function. | Basal plasma prolactin levels and values after stimulation with TRH and chlorpromazine respectively were measured. TRH tests were performed in 50 healthy subjects (25 women and 25 men). The basal prolactin levels and the maximum increment were found to be as follows in women 22.02 ng/ml | 808,064 | [
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0.08101944,
... |
Hairy cell leukemia ('leukemic reticuleondotheliosis'), reticulosarcoma, and monocytic leukemia. Cytochemical and ultrastructural investigations. | Cytochemical and electron-microcopic studies have been carried out on leukemic monocytes and 'hairy cells' (HC), 'reticulosarcoma' (RS) cells and cells of cases of 'reticulosis' and 'reticulosarcoma cell leukemia'. Additional investigations included equantitative determinations of the urinary lysozyme excretion, skin w... | 808,067 | [
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0.05535222,
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0.05452355,
0.1293798,... |
Functional heterogeneity of the transport iron compartment I. In vivo radioiron clearance from high and low saturated transferrin. | Two transferrin solutions of 4 and 80% 59Fe saturation respectively were administered to humans 30 min apart. The radioiron clearnce from the high saturated preparation was significantly accelerated. Comparable results were obtained in rats when normal rat serum was used instead of purified transferrin. | 808,069 | [
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... |
A trial of disodium cromoglycate in perennial rhinitis. | In this investigation, a double-blind, cross-over trial of sodium cromoglycate in 23 patients with perennial rhinitis was carried out. An improvement in symptoms was found in actively-treated patients, and a greater preference was expressed for active treatment. There was no relationship between response to sodium crom... | 808,082 | [
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0.1945928,
0.0863,
-... |
Antithrombin in infancy and childhood. | Antithrombin III was measured immunologically, and antithrombin activity was measured with aid of a new synthetic tripeptide substrate for serine proteases in plasma of healthy infants and children, 0-14 years of age. Both methods gave decreased values in the youngest infants as compared with adults. The antithrombin i... | 808,091 | [
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0.4542623,
0.4241673,
0.2042572,
-0.1616971... |
Infection of Microtus arvalis (common vole) with Mycobacterium tuberculosis and Mycobacterium bovis. | The aim of the study has been to ascertain whether Microtus arvalis (common vole) is strongly susceptible to M. bovis but resistant to M. tuberculosis, as is the case with other members of the vole family, or whether it is susceptible to both species as demonstrated by Robert Koch. Groups of common voles have been inje... | 808,093 | [
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0.3828611,
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0.1714899,
0.02928001,
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Partial purification and separation of multiple forms of cytochrome. P-450 and cytochrome P-448 from rat liver microsomes. | 1. Partial purification of liver microsomal cytochrome p-450 results in the separation of two forms of cytochrome p-450 from phenobarbital-treated rats and two forms of cytochrome p-44, from 3-methylcholanthrene-treated rats. 2. Each of the four cytochrome fractions had different spectral properties (absolute spectra, ... | 808,108 | [
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0.2295628,
0.2430326,
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0... |
Cell-mediated immunity in Hurler's syndrome. | Cell-mediated immunity was investigated in 3 brothers with Hurler's syndrome (Gargoylism). The response to infectious antigens and PHA stimulation and sensitization to DNCB was considered normal in two patients. DNCB sensitization occurred after 18 days in the oldest brother (16 years old) and only 25 days in the secon... | 808,113 | [
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0.3025974,
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0.2424437,
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... |
Neonatal dystrophia myotonica. Electrophysiologic studies. | The diagnosis of dystrophia myotonica was established in a boy 3 hours old, and confirmed by family study and electromyography (EMG) at 5 days. Clinical features included hypotonia, facial diparesis, "tented" upper lip, and arthrogryposis of both knees. Percussion myotonia was elicited. The EMG disclosed characteristic... | 808,120 | [
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-0.05352754,
... |
Heterotopic bone formation in abdominal incisions. | 1. Heterotopic bone formation in abdominal scars is not as rare as the paucity of case reports in the literature would indicate. 2. Females comprised 21 percent of our patients. 3. The average age was fifty-five years. 4. The probable cause of this bone formation is injury to the xiphoid process above or the pubis belo... | 808,146 | [
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Relationship between serum immunoglobulin, inhalation bronchial challenges and skin tests in severe asthmatics. | The relationship among inhalation bronchial challenge tests, skin tests, total serum immunoglobulin E, A, M, and G values were investigated. Positive correlation between the results of the inhalation bronchial challenges and IgG and negative correlation between the value of IgG and IgA were found but no other correlat... | 808,151 | [
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[Traumatic esophageal pseudodiverticulum (author's transl)]. | Hypoharyngeal perforation with production of an esophageal pseudodiverticulum in the newborn is reviewed. Two new cases are reported and the clinical signs, very similar to those of tracheoesophageal fistula with esophageal artresia, commented upon. The radiological findings of the lesion are discussed, and hints on co... | 808,153 | [
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Basis for the resistance of several algae to microbial decomposition. | The basis for the resistance of certain algae to microbial decomposition in natural waters was investigated using Pediastrum duplex, Staurastrum sp., and Fischerella muscicola as test organisms. Enzyme preparations previously found to convert susceptible algae into spheroplasts had no such effect on the resistant speci... | 808,166 | [
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Microflora and invert sugars in juice from healthy tissue of stored sugarbeets. | Bacterial populations increased in juice of healthy tissue of sugarbeet roots stored at 5 C. Average counts showed a sixfold increase after 150 days of storage. Invert sugar levels increased over threefold in "American 4 Hybrid A" and remained fairly constant in "Mono-Hy D-2." The former cultivar also had significantly... | 808,167 | [
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Requirement of low oxidation-reduction potential for photosynthesis in a blue-green alga (Phormidium sp.). | Photosynthesis in a Phormidium species which forms dense conical-shaped structures in thermal springs is strongly inhibited by aeration but is stimulated by sulfide and other agents (cysteine, thioglycolate, sulfite) which lower the oxidation-reduction potential. The compact structures which this alga forms in nature ... | 808,187 | [
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[Diurnal progress of NADP-linked glyceraldehyde-3-phosphate-dehydrogenase in synchronous culture of unicellular green alga Ankistrodesmus braunii and its susceptibility to X-irradiation and inhibitiors of protein synthesis]. | 1. The daily progress of NADP-linked GPD-activity rise in synchronous culture of Ankistrodesmus braunii was investigated in respect to short time increase of activity by light. After various exposure times cells were temporarily deprived of light and subsequently the so-called dark value as well as the light value (dar... | 808,190 | [
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The clearing-factor lipase activity of isolated fat-cells. | 1. When fat-cells are isolated from the epididymal adipose tissue of 24h-starved rats and incubated at 25 degrees C in the presence of dialysed serum, glucose, insulin, amino acids and heparin, the total clearing-factor lipase acitivity of the incubation system increases progressively over a period of several hours. 2.... | 808,220 | [
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Effect of depletion of vitamin A, followed by supplementation with retinyl acetate or retinoic acid, on regeneration of rat liver. | After partial hepatectomy the net increase in tissue weight and in RNA, DNA and proteins in the regenerating liver was markedly less in vitamin A-deleted or retinoic acid-supplemented male rats, compared with the corresponding normal control or retinyl acetate-supplemented ones. | 808,221 | [
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The teichuronic acid of cell walls of Bacillus subtilis W23 grown in a chemostat under phosphate limitation. | Cell walls of Bacillus subtilis W23 contain teichuronic acid when grown in a chemostat under phosphate limitation at a low dilution rate, but teichoic acid at a higher dilution rate. The teichuronic acid was purified and shown to be a polymer of glucuronic acid and N-acetylgalactosamine. | 808,222 | [
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A controlled study of the hypoglycemic and insulinopoietic effect of glipizide and glibenclamide in non-diabetic human subjects. | The authors studied in 12 non-diabetic women the effect on blood glucose and IRI of 2.5 mg of N-(4-[2-5-methylpyrazine-2-carboxamido)-ethyl]-benzenesulphonyl)-N'-cyclohexyl-urea (glipizide) and N-4[2-5(-chloro-2-methoxy-benzamido)-ethyl]-phenylsulphonyl-N'-cyclohexyl-urea (glibenclamide) given orally as a single dose a... | 808,231 | [
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RNA synthesis and the accumulation of guanine nucleotides during growth shift down in the blue-green alga Anacystis nidulans. | Shift down of growth rate in the blue-green alga Anacystis nidulans by reduction of the incident light intensity produced a reduction in the rate of stable RNA accumulation which was correlated with increased concentrations of three phosphorylated compounds, two of which were identified as guanosine 5'-diphosphate-3'-d... | 808,240 | [
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Cultural perceptions and nutritional disorders: a Jamaican case study. | This case study brings out differences in the way protein-calorie malnutrition (PCM) in Jamaica is regarded by women who use medical services, women who do not, indigenous health practitioners, and trained health workers. The study reveals that women who utilize modern health clinics are able to identify appropriate t... | 808,243 | [
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[Mechanisms of phosphate ion absorption in chlorella: the effect of N-ethylmaleimide (NEM) on phosphate transport]. | N-ethylmaleimide was found to inhibit phosphate uptake in Chlorella pyrenoidosa. For very short incubation times, this inhibitor seems to react only with the surface of cells. In this case, inorganic phosphate provides protection against the effect of NEM. | 808,276 | [
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[Cardiotropic effects of C 18 synthetic juvenile hormone of Hyalophora cecropia on Locusta migratoria L]. | C 18 Cecropia juvenile hormone injected at doses of 50 and 100 mug/animal in larval instar and of 200 mug/animal in the adults, increases the heartbeat of the fifth instar and males and females of Locusta migratoria in the same way as the implantation of one pair of corpora allata. | 808,303 | [
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[A paragonial substance extracted from spermatophores of Acanthoscelides obtectus Say (Coleoptera: Bruchidae). Isolation of the active fraction]. | A compound responsible for the stimulation of oogenesis observed after copulation is present in the spermatophores produced by the male accessory glands of the bean weevil Acanthoscelides obtectus. A purified biologically active fraction of low molecular weight has been obtained by repeated chromatographies on "Sephade... | 808,308 | [
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[The polymorphism of the polytene chromosomes of Bilobella aurantiaca Caroli (Collemboles) and its biogeographic and ecologic significance]. | Collembola Bilobella aurantiaca lives in forest biotopes all around the western Mediterranean sea; it shows a great polymorphism of polytene Chromosomes (2n = 14). This polymorphism is founded on differences of band-pattern and overall on alpha-heterochromatic overcharges at certain points. Examples are given for the c... | 808,313 | [
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[Establishment of a primary culture of cells from embryonic tissue of Loliyo vulgaris L.(Cephalopod)]. | The author studies the behaviour in vitro of organ fragments of Loligo vulgaris embryos at hatching stage. These fragments are maintained in three different media. The time of survival of cells is 20 to 25 days in the medium I(sea water), 40 days in the medium II(perivitellin fluid) and 70 to 80 days in the medium II(p... | 808,330 | [
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[Production of a dialysable transfer factor of cell mediated immunity by lymphoblastoid cells in continuous proliferation]. | Four lymphoblastoid cell lines tested in this work contain normally a dialysable moiety having by ultraviolet spectroscopy, column chromatography (Biogel P 10) and chemically the same properties than human dialysable Transfer Factor (TFd), but unable to transfer cell mediated immune response against common antigens. Tw... | 808,340 | [
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Use of the reference method for determination of serum calcium in a quality-assurance survey. | The Reference Method [Clin. Chem. 19, 1208 (1973)] for determination of total calcium in serum has been applied to 29 specimens from the Wellcome Group Quality-Control Programme. The accuracy of the mean results for all participants, and for selected groups of participants, was determined over the concentration range 2... | 808,364 | [
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[Treatment of atypical absences with a combination of succinimide and dipropylacetate (author's transl)]. | Fifteen epileptic patients with mild seizures of the narcolepsy type were treated with a combination of succinimide (average dose 750 mg) and dipropylacetate (average dose 1,200 mg), medication with each drug alone having brought no success. The combination of drugs stopped the seizures in eleven patients, in three the... | 808,402 | [
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Alcoholic detosis. | Twenty-four chronic alcohol abusers hospitalized during a twenty-seven-month period were suspected of having "alcoholic ketoacidosis" because they had ketonuria or ketonemia with little or no glucosuria. Twenty-one had moderate or severe ketosis, with plasma 3-hydroxybutyrate of 5.2 to 22.5 mmol/L. Fifteen of this grou... | 808,436 | [
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In situ production of a synthetic barrier dressing for burn wounds in rats. | We describe the in situ production of a burn wound dressing applied to eschar that completely isolates burned tissue from contamination with Pseudomonas aeruginosa. Anesthetized, adult rats were subjected to a scald burn over 10% of their body surfaces. One-half hour later a test dressing presumed to be a barrier to ba... | 808,499 | [
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The rates of ion movement from plasma to aqueous humor in the dogfish, Squalus acanthias. | Aqueous humor dynamics were studied in the dogfish, Squalus acanthias, using isotopically labeled inulin, Na+, Cl-, and HCO-3. Fluid production was 100 mul per hour, with a turnover rate constant of 0.4 hr.-1, about half that of mammals. The ciliary process contains carbonic anhydrase and Na-K-ATPase. Diffusion of Na+ ... | 808,513 | [
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Histology of the monkey lateral geniculate nucleus after unilateral lid closure and experimental strabismus: further observations. | The histology of binocularly and monocularly innervated portions of the lateral geniculate nucleus (LGN) was studied after unilateral lid closure and experimental esotropia and exotropia in the Macaca mulatta and the results were compared with behavioral and neurophysiological data. The most severe cell shrinkage occur... | 808,514 | [
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Antraformin, a new inhibitor of Bacillus subtilis transformation. | A convenient method was worked out which discriminates between inhibitory activity of compounds against Bacillus subtilis transformation and their antibacterial or growth inhibition activity. By this assay system, several drugs and antibiotics were tested and some of them were found to be more inhibitory to transformat... | 808,524 | [
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Receptors for chemotaxis in Bacillus subtilis. | At least three receptors for chemotaxis toward L-amino acids in Bacillus subtilis could be found with the aid of taxis competition experiments. They are called the asparagine receptor, which detects asparagine and glutamine, the isoleucine receptor, which detects isoleucine, leucine, valine, phenylalanine, serine, thre... | 808,536 | [
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0.07387087,
... |
Facultative anoxygenic photosynthesis in the cyanobacterium Oscillatoria limnetica. | An isolate from H2S-rich layers of the Solar Lake, the cyanobacterium Oscillatoria limnetica, exhibits both oxygenic and anoxygenic photosynthesis. It can use Na2S as an electron donor for CO2 photoassimilation (photosystem I supplies the energy) in the presence of 3-(3,4-dichlorophenyl)-1,1-dimethylurea or 700-nm ligh... | 808,537 | [
-0.1019767,
0.04371334,
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0.1553156,
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0.4360034,
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-0.6331794,
0.2749889,
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0.004266957,
0.4987777,
0.1477836,
-0.0303721... |
Substrate concentration dependence of the rate of maltose hydrolysis by saccharifying alpha-amylase from B. subtilis. | 1. The action of saccharifying alpha-amylase from B. subtilis [EC 3.2.1.1] on eq- (the equilibrium mixture of alpha- and beta-forms) and beta-maltose was studied at pH 5.4 and 25 degrees. 2. The plots of initial velocity versus substrate concentration showed remarkable sigmoidal curves for both substrates. 3. The value... | 808,539 | [
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0.1587754,
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0.04887179,
0.6575103,
-0.03345102,
0.01858... |
Colchicine-binding protein of the liver. Its characterization and relation to microtubules. | Colchicine-binding activity of mouse liver high-speed supernate has been investigated. It has been found to be time and temperature dependent. Two binding activities with different affinities for colchicine seem to be present in this high-speed supernate, of which only the high-affinity binding site (half maximal bin... | 808,552 | [
-0.09021267,
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-0.3533305,
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-0.0558218,
0.4998994,
0.440782,
0.3131948,
0.0597281... |
Studies on phenolic steroids in human subjects. XIV. Fate of a nitrogen mustard of estradiol-17beta. | Estracyt, a conjugate of estradiol-17beta (E2) and a nitrogen mustard, is a compound which recently has been found to be of value in the treatment of cancer of the prostate. The present study concerned itself with the fate of labeled Estracyt administered 1) either as a mixture of 3H-Estracyt, labeled in the estrogen m... | 808,555 | [
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0.1083481,
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0.1213014,
0.1842687,
0.3836772,
-0.1551957,
0.020792... |
Interruption of the arterial inferior alveolar flow and its effects on mandibular collateral circulation and dental tissues. | The interruption of circulation through the inferior alveolar artery was followed by the establishment of a fast retrograde blood flow through the vessel. The mental artery and the mandibular branch of the sublingual artery were the main vessels to contribute to that flow. No histopathologic changes were found in the e... | 808,564 | [
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0.03653743,
-0.1804067,
0.2105977,
0.05899231,
0.1170... |
Ulcerative colitis in apes: A comparison with the human disease. | The pathological changes in the colons of two young gorillas and an adult orang-utan which developed diarrhoea and died, are described. Since no causative agents could be identified and the changes were indistinguishable from the active phase of ulcerative colitis in humans, these cases were considered examples of this... | 808,598 | [
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0.1634672,
0.05265303,
0.2203018,
0.08185196,
0.3956077,
-0.0871235... |
The kinetics of resealing of washed erythrocyte ghosts. | The kinetics of resealing, defined as the recovery of impermeability to macromolecules, of well-washed human erythrocyte ghosts has been determined. The resealing process is first-order at temperatures above 20-25 degrees C in isotonic salt, with rate constants ranging from 0.01-0.15 min-1. Below 20 degrees C, resealin... | 808,630 | [
0.01490007,
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0.09007762,
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0.03002348,
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0.1225197,
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0.1735689,
0.0283139,
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0.1024244,
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0.0509865,
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0.4449184,
-0.05927021,
0.2701741,
0.2481403,
0.2452872,
-0.002639104... |
Metabolic reduction of benzidine azo dyes to benzidine in the rhesus monkey. | Rhesus monkeys were fed azo dyes derived from benzidine (a known human bladder carcinogen). The urinary excretion of free benzidine was assayed and compared to the amount excreted when benzidine itself was fed. A substantial amount of the dye fed was converted to free benzidine. Results indicate that the simple precaut... | 808,635 | [
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0.08422145,
0.08458493,
0.2273554,
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0.1928371,
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0.004822203,
0.2141363,
0.07935008,
... |
Anticonvulsant nature of marihuana smoking. | Marihuana smoking, in conjunction with therapeutic doses of phenobarbital and diphenylhydantoin, was apparently necessary for controlling seizures in one 24-year-old epileptic patient. | 808,653 | [
-0.1925469,
0.2180538,
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0.3249455,
0.2201632,
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0.4602654,
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0.060146,
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0.1687195,
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0.5258728,
0.02546833,
0.1289191,
-0.0412228,
0.2073811,
-0.02945815,
-0.... |
The hypothalamic-pituitary-thyroid axis. | Although recent investigations have contributed greatly to our understanding of the function and regulation of the hypothalamic-pituitary-thyroid axis, much remains unclear. The influence of suprahypothalamic areas of the brain on hypothalamic function, the nature of thyroid hormone feedback on the hypothalamus, and th... | 808,671 | [
0.09947041,
-0.4008491,
0.08046833,
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0.1782225,
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0.05284013,
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0.2647199,
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0.2055184,
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-0.2279995,
-0.2987788,
0.06995722,
0.02910068,
-0.1565812,
0.2468546,
0.3022036,
-0.02608012... |
The comparison of rat liver rough endoplasmic reticulum membrane proteins before and after in vitro removal of its bound ribosomes. | The comparison of the proteins of rat liver rough membrane after stripping with EDTA or KCl-puromycin by two dimensional gel electrophoresis is described. By stripping the membrane with EDTA, most of the basic ribosomal proteins are still attached to the membrane; in contrast to the EDTA stripping method, treatment wit... | 808,702 | [
0.008065078,
0.2247639,
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0.02700721,
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0.01500807,
0.3066679,
0.1625,
0.126018,
0.003769192,
0.3677668,
0.2865463,
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-0.3160821,
-0.3306783,
-0.3247187,
-0.1139831,
0.09685784,
0.05733642,
0.03175117,
... |
Membrane formation by autotransplanted retinal pigment epithelium (RPE). | Autotransplanted RPE cells after free intravitreal injection or in millipore diffusion chambers placed into the vitreous cavity undergo metaplasia: they first show the characteristics of macrophages. Later they transform into spindle-shaped cells or even into pigment epithelium-like cells. The latter two cell types hav... | 808,705 | [
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0.1936109,
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0.1212654,
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0.2028243,
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-0.1993599,
0.480682,
-0.1706541,
-0.1871825,
... |
[Pharmacokinetics of intravenous Cefradin in normal and restricted renal function (author's transl)]. | Half life and distribution volume of Cefradin were investigated in 22 patients with various degrees of renal function in which Cefradin was indicated and set in relation to glomerular filtration (determined by the 51Cr EDTA method). An average distribution volume of 21.8 +/- 3.5% of the body weight was found and a corr... | 808,712 | [
0.05123967,
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0.2708052,
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0.2423606,
0.2601965,
0.260431,
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0.6192617,
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0.2758181,
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0.3179242,
0.3359735,
0.2555266,
0.2869013,
0.057... |
A family with coexistent von Recklinghausen's neurofibromatosis and von Hippel-Lindau's disease. Diseases possibly derived from a common gene. | A large kindred has two coexistent neurocutaneous syndromes: Certain members appear to have von Recklinghausen's neurofibromatosis (cutaneous neurofibromata, cafe-au-lait spots), others have von Hippel-Lindau's disease (angiomatosis retinae, renal cell carcinomas, pancreatic cysts), and at least one individual has a co... | 808,759 | [
0.008522158,
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0.0335509,
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0.1201101,
0.3112355,
0.2912535,
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-0.1125409,
0.4002712,
-0.009302613,
0.06907377,
0.1652888,
-0.06865374... |
Characteristics of juvenile rheumatoid arthritis: its medical and orthopedic management. | The characteristics of juvenile rheumatoid arthritis have been presented and the important features of its medical and orthopedic management described. Surgical experience in a carefully studied group of 200 patients has been recounted. The increasing importance of reconstructive joint surgery is noted, preferably perf... | 808,780 | [
-0.0143476,
0.02762686,
-0.1219408,
-0.2659927,
-0.3174424,
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-0.3496125,
0.01540985,
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0.03990763,
0.2100708,
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0.01729191,
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0.2940167,
0.2298143,
0.1132948,
0.1017061,
0.3166398,
0.2618814,
-0.1982842,
-0.1192098,
0... |
Rickets associated with long-term anticonvulsant therapy in a pediatric outpatient population. | Over a 12-month period, an ambulatory pediatric population receiving long-term anticonvulsants was surveyed for the presence of biochemical and radiologic rickets. There were 74 treated children and 95 matched controls. Elevations of serum alkaline phosphatase activity occurred in 31 of the 74 (42%) treated children (2... | 808,788 | [
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-0.1193435,
-0.3729075,
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-0.2841268,
-0.3337517,
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-0.02825132,
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0.1350898,
0.3657737,
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0.3906386,
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0.005507198,
-0.3334494,
0.3432613,
0.3412208,
0.140149,
-0.0384825,
0.2719012,
-0.1500656,
... |
Streptococcal sore throat followup program in a hospital clinic, New York City. | To improve followup and treatment of patients with streptococcal sore throat at St. Vincent's Hospital and Medical Center, New York City, a simple and inexpensive method was devised for recalling and treating untreated patients with positive throat cultures and culturing household contacts. The program was conducted by... | 808,824 | [
-0.2256819,
0.05122556,
-0.1004224,
-0.2285588,
-0.1080783,
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-0.4221993,
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0.1124703,
0.02915352,
0.01461001,
0.03058936,
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0.1226726,
-0.2334729,
-0.2149383,
0.2439979,
0.09186624,
-0.1574668,
0.0070... |
The comparative metabolism of zolazepam in rat, dog and monkey. | The metabolic disposition.of zolazepam, a pyrazolodiazepinone, was studied in male and female Spartan rats, Beagle dogs and Rhesus monkeys. Six principal urinary metabolites were characterized by gas chromatography and combined gas chromatography-mass spectrometry. The major metabolite in male and female rats was produ... | 808,840 | [
-0.08861822,
0.4806168,
-0.3124347,
-0.4403232,
0.07827783,
-0.2908208,
-0.3518115,
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0.009610762,
-0.1488624,
0.225253,
0.05560925,
0.008215942,
0.1833714,
-0.5180076,
-0.1897612,
-0.5170498,
0.2616997,
0.4088238,
0.008384657,
0.09824193,
0.1532347,
-0.103777,
... |
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