title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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[Absences and absence-like crises]. | Under the same clinical picture the "absence" may group various forms of epileptic and non-epileptic disease entities, each having a different pathogenesis and a different EEG correlate. The investigative procedures, therapy and prognosis are likewise non-uniform. This suggests the need for a nomenclatorial division fo... | 808,848 | [
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Chemotaxis away from uncouplers of oxidative phosphorylation in Bacillus subtilis. | In a capillary assay, uncouplers of oxidative phosphorylation and inhibitors of electron transport are repellents for Bacillus subtilis. They also cause transient tumbling in naturally smooth swimming strains. Tumbling strains can be made to swim smoothly by addition of attractant and then immediately returned to tumbl... | 808,854 | [
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A contribution to the knowledge of the so-called pyloric band ("double pylorus"). | Two new cases of patients with so called muscular pyloric band ("double pylorus") are reported. Both possible genetic mechanisms of this malformation are discussed in detail: primary or congenital, and secondary or acquired by inflammation. After analysis of the hitherto related cases, the opinion is expressed that the... | 808,895 | [
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The structure of the human juxtaglomerular apparatus. A morphometric, lightmicroscopic study on serial sections. | 49 juxtaglomerular apparatuses were examined using 1.9mu thick Giemsa-stained serial sections from human renal tissue embedded in plexiglass. In 43 juxtaglomerular apparatus the direct contact areas between the different juxtaglomerular structures and the basal area of the macula densa were calculated. A positive, sign... | 808,896 | [
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[Investigations on the utilization of parenterally administered amino acids by premature and small-for-dates neonates. I. Free amino acids in the blood of premature and small-for dates neonates (author's transl)]. | The fasting levels of free amino acids were determined in the serum of 23 premature and 7 small-for-dates newborns during the first 4 weeks of life. This was done by ion-exchange chromatography after ultrafiltration of the serum, which allowed quantification. Differences were recognized in regards to age, and nutrition... | 808,914 | [
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[Studies on the reduction of microorganisms in icecream in production and storage (author's transl)]. | Experimental analyses referred to in this publication were to clarify two important hygienic-bacteriological issues: 1. Which is the capacity of survival owned by microorganisms in icecream in correspondence to temperature and storing time, and what significance have the results in regard to the length of intervals bet... | 808,925 | [
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Autotransufsion of 3H-cytidine-labelled blood lymphocytes in patients with Hodgkin's disease and non-Hodgkin patients. I. Limitations of the method. | Autotransfusion of 3H-cytidine-labelled blood lymphocytes followed by autoradiographic evaluation as studied in 11 patients with Hodgkin's disease and pool sizes of lymphocytes. However, it is complicated by two major pitfalls; (1) The free (extracellular) activity of oH-cytidine transfused along with the cell-bound la... | 808,929 | [
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Massive splenomegaly, pancytopenia and haemolytic anaemia in sarcoidosis. | A 53-year-old dock labourer, presented with massive splenomegaly and subsequently developed pancytopenia. Complete haematoglogical remission was observed following splenectomy. Histological examination of the liver and spleen revealed sarcoid granulomata. A year after splenectomy, he died in an acute haemolytic crisis,... | 808,933 | [
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Urine porphyrins and their precursors in homozygous beta-thalassaemia. | In 68 patients with homozygous beta-thalassaemia the excretion of porphyrins and porphyrin precursors in urine has been assayed. Though a definite excretion pattern has not been established, the majority of the thalassaemics excrete an increased amount of coproporphyrin and porphobilinogen. The results are compared t... | 808,946 | [
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Depression of lecithin-cholesterol acyltransferase esterification in vitamin E-deficient monkeys. | Vitamin E deficiency in two species of monkeys (capuchins and cynamolgus) reduced the in vitro cholesterol esterification by plasma lecithin-cholesterol acyltransferase. The reduction was greates in the most deficient species and in animals fed a diet rich in polyunsaturated fat (safflower oil) stripped of vitamin E. T... | 808,956 | [
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Accessibility of the (14C)benzylpenicillin binding proteins in membranes of sporulating bacilli. | Triton X-100 treatment or freeze-thawing damages the membranes of sporulating or vegetative cells as seen by protein leakage from cells. A 40% increase in the specific [(14)C]benzylpenicillin-binding capacity of detergent-treated or frozen sporulating cells was observed. Neither freezing nor Triton X-100 treatment of v... | 809,003 | [
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An assessment of antibiotics for the treatment of pyogenic dental infections. | Tests made with a series of antibiotics against a number of different organisms indicate that if clinical evidence suggests a streptococcal infection, penicillin should be used otherwise erythromycin is preferred. | 809,025 | [
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The serological diagnosis of bovine brucellosis: an evaluation of the complement fixation, serum agglutination and rose bengal tests. | In a collaborative investigation in which 4 laboratories took part, the Rose Bengal Test (RBT), Serum Agglutination Test (SAT) and 4 different Complement Fixation (CFT) techniques were evaluated in selected cattle for the diagnosis of bovine brucellosis, by comparing the results they gave with the bacteriological exami... | 809,027 | [
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Physiological and environmental control of Gram negative bacteria on skin. | The relative importance of the environment versus the physiology of the host in the control of Gram negative bacteria on skin has been examined by two experimental designs. (I) The changes in incidence of Gram negative carriage from three skin sites in a climate controlled chamber at 35 degrees C and 90% humidity for 6... | 809,052 | [
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Delipidation of the phosphatidylcholine exchange protein from beef liver by detergents. | 1. A method is described to introduce [14C] phosphatidylcholine into the phosphatidylcholine exchange protein from beef liver. The effects of various detergents on this 14C-labelled phospholipid - protein complex are considered. 2. As shown by spectrophotometric and radioactivity analysis of polyacrylamide gels, sodium... | 809,056 | [
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Progress in the classification of lymphoid and/or monocytoid leukemias and of lympho and reticulosarcomas (non-Hodgkin's lymphomas). | New methods helpful in the classification of lymphoid and monocytoid leukaemias and haematosarcomas have recently become available. Among the most valuable procedures have been those detecting immunological markers and the ultrastructural analysis permitted by convention and scanning electron microscopy. The results of... | 809,067 | [
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Bovine factor v: a calcium-containing metalloprotein. | Although coagulation factor Xa requires Ca2+ for binding to phospholipid, factor V, the other protein component in the prothrombinase enzyme complex, binds tightly to phospholipid in the absence of Ca2+. To explore the possibility that calcium might be present in the fact V molecule, the effect of several chelators, in... | 809,072 | [
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Effect of lithium on hypothalamic-pituitary-thyroid function in patients with affective disorders. | Hypothalamic-pituitary-thyroid (H.P.T.) function was assessed in 17 patients on maintenance doses of lithium carbonate for a mean period of 21 months (range 1-67 months) and by serial studies on four patients from the start of lithium treatment for a maximum of six months. An exaggerated thyrotrophin (TSH) response to ... | 809,083 | [
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Utilization of calcium pools during pharmaco or electromechanical coupling in smooth muscle. | Isometric contraction of cat spleen capsule due to noradrenaline had a fast and a slow phase. These phases were due to a tightly and a loosely bound (or extracellular) pool of calcium, respectively. Depolarization due to high potassium caused mainly a reduction of the slow phase. In sodium-loaded spleen strips recoveri... | 809,122 | [
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Germination of Bacillus cereus endospores: a proposed role for heat shock and nucleosides. | Spores of Bacillus cereus T prepared in a glucose - yeast extract - salts broth germinated in L-alanine or more rapidly in L-alanine plus inosine or adenosine. The nucleosides alone were not germinative. Inosine was shown to produce no pregerminative changes in spores that prepared them for more rapid germination later... | 809,124 | [
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The effects of feedback on focal epileptic discharges in man. A preliminary report. | The history of the control of epileptic disturbances by conditioning techniques is reviewed. The preliminary results of a three year trial of feedback techniques in 13 epileptic patients are presented. Thirteen epileptic patients (age 2.5 leads to 39 mean, 15.1 years) with lateralized focal discharges in the EEG were g... | 809,125 | [
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Lowering effect of carbon tetrachloride on microsomal cytochrome P-450 of rat liver. | The lowering effect of carbon tetrachloride (CCl4) on the amount of hepatic microsomal cytochrome P-450 of male rats was studied in vitro. It was found that CCl4 added directly into the media containing microsomal supensions decreased the amount of cytochrome P-450 detectable by difference spectra at zero time of incub... | 809,145 | [
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[Intrinsic regulation of the growth of mandibular condyle cartilage: inhibition of prechondroblastic proliferation by chondroblasts]. | In organ culture, the chondroblasts of the rat mandibular condyle cartilage inhibit the mitotic activity of the prechondroblasts. Hypertrophy of the chondroblasts decreases their inhibitory action. The hypothetical "inhibitory signal" might be a chalone-like substance. | 809,200 | [
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Properties of the residual alpha-galactosidase activity in the tissues of a Fabry hemizygote. | The properties of the residual alpha-galactosidase activity in kidney, liver, spleen, fibroblasts and urine of a Fabry hemizygote have been studied using p-nitrophenyl-alpha-galactoside and 4-methylumbelliferyl-alpha-galactoside as substrates. In addition, alpha-galactosidase activity in urine has been determined with ... | 809,216 | [
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Interaction of sudoxicam and aspirin in animals and man. | In rats, both the plasma concentrations and the anti-inflammatory activity of sudoxicam are depressed by concurrent administration of aspirin, being similar to that reported for other nonsteroidal agents, whereas, in man and monkey, plasma concentrations of sudoxicam are not affected by concurrent administration of asp... | 809,225 | [
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Interaction of estradiol and LHRH on LH release in rhesus females: evidence for a neural site of action. | The effects on LH release of infusing luteinizing hormone-releasing hormone (LHRH 80 mug/20 min) into the third ventricle, the pituitary, and the peripheral circulation were compared in spayed rhesus monkeys. Within 30 min after iv administration, serum LH concentrations increased to twice to preinfusion levels, and by... | 809,257 | [
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Estimation of the maximal T4-binding capacity of TBG using the Triosorb test in serum treated with dextran-coated charcoal. | A new method for the estimation of the maximal T4-binding capacity of TBG (max. TBG) in serum (dextran-coated charcoal-triosorb method) was devised. Thyroxine (T4) concentration in test sera were determined by the Tetrasorb method and then T3 resin sponge uptake (T3 RSU) was determined after extraction of 70% of the en... | 809,258 | [
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... |
Lack of TRH-induced TSH secretion in a patient with Klinefelter's syndrome: a case report. | In a 41 year-old patient with Klinefelter's syndrome, a failure of TRH-induced TSH secretion was noticed. Low 131I-thyroid uptake, together with the elevation following exogenous TSH administration, indicates that the defective locus exists in the hypothalamus or pituitary resulting in an impaired secretion of TSH. Suc... | 809,259 | [
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0.09994514,
0.1067382,
0.01023866,... |
Changes in the state of actin during superprecipitation of actomyosin. | Exchangeability of actin-bound ADP and calcium in actomyosin at low ionic strength has been studied using F-actin labelled with [14C]ADP or 45Ca and measuring release of radioactivity into solution. Low-speed centrifugation, ultracentrifugation and ultrafiltration were used to separate protein from the medium. Comparis... | 809,272 | [
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0.2823783,
0.6722035,
0.01954789,
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On the denticles of the sublingua in Galago crassicaudatus E. Geoffrey, 1812 (Primates, Prosimiae, Lorisiformes). | The denticles of the sublinguae of Galago crassicaudatus and G. senegalensis are studied histologically. There are, at the oral end of the sublingua, main or primary denticles which bear on their surface the much smaller secondary denticles. Spine-like small denticles occur on the surface of the ventromedian keel also.... | 809,325 | [
0.1671172,
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... |
[Pattern of antibody structure. The amino acid sequence of a monoclonal immunoglobulin L-chain of lambde-type, subgroup I (Bence-Jones-protein Vor.). A contribution to the elucidation of the origin of antibody specificity (author's transl)]. | The experiments leading to the determination of the primary strucutre of Bence-Jones-Protein Vor. are reported. The variable part of this immunoglobulin polypeptide chain can easily be identified as a typical representative of subgroup I of the lambde-chains. The constant part is characterized by the Kern- and OZ+ mark... | 809,332 | [
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0.3593516,
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... |
Genetic variations in primates. Red cell enzymes and serum proteins in Macaca mulatta. | Blood and serum from 17 Macaca mulatta were analysed for haptoglobins, transferrins, 6-phosphogluconate dehydrogenase, adenylate kinase, adenosine deaminase, phosphoglucomutase, acid phosphatase, glucose-6-phosphate dehydrogenase and phosphohexose isomerase. Compared to the human pattern, the AcPh and the ADA component... | 809,345 | [
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Human secretory immunoglobulin M. An immunochemical and immunohistochemical study. | IgM was purified from normal human colostrum and salivary secretions devoid of IgA. The isolated immunoglobulin was found to contain J chain, and showed a slight affinity for free secretory component (SC). In the secretions IgM was saturated with SC, but only 60--70 per cent of the molecules had retained the component ... | 809,350 | [
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... |
Response of sublethally irradiated monkeys to a replicating viral antigen. | Temporal effects of exposure to sublethal, total-body X radiation (400 R) on responses to vaccination with attenuated Venezuelan equine encephalomyelitis vaccine virus. TC-83, were examined in rhesus monkeys. Viremia, often with delayed onset, was prolonged even when irradiation preceded vaccination by 28 days. Virus t... | 809,358 | [
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0.5714651,
0.3695933,
0.1081903,
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... |
Coccidioidomycosis in a rhesus monkey. | Coccidioidomycosis was diagnosed after necropsy of a young adult male rhesus monkey obtained from El Paso, Tx. Clinical signs were confined to the respiratory tract and included tachypnea and dyspnea. Radiographic findings included multiple air-filled cavities and evidence of severe diffuse pulmonary disease. Pathologi... | 809,398 | [
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0.0359463,
0.2501528,
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... |
Cardiac norepinephrine stores and chronotropic reflex response after thoracotomy. | Although alterations in cardiac reflex activity, as well as in cardiac norepinephrine stores, have been shown following thoracic operations, the physiological relationship between these alterations has not been investigated. Cardiac norepinephrine stores were examined in 17 normal dogs, and in 16 dogs 1-6 wk after a ri... | 809,409 | [
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0.348591,
0.2308757,
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0.1025496,
0.1590116,
0.05196423... |
Pleiotropic phenomena in autolytic enzyme(s) content, flagellation, and simultaneous hyperproduction of extracellular alpha-amylase and protease in a Bacillus subtilis mutant. | A mutant of Bacillus subtilis 6160 that had been isolated by its hyperproduction of alpha-amylase and protease lacked flagella and motility, and its content of autolytic enzyme(s) was reduced to one-third to one-fourth that of the parent. These phenotypic differences were completely co-transferred by the deoxyribonucle... | 809,421 | [
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0.1414707,
0.3385769,
0.1951247,
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-... |
Purification and properties of some unique low molecular weight basic proteins degraded during germination of Bacillus megaterium spores. | Two major proteins, termed proteins A and B, and one minor species, termed protein C, have been purified to homogeneity from dilute acid extracts of dormant spores of Bacillus megaterium. These three species comprise approximately 80% of the protein in the dilute acid extracts and account for 60 to 75% of the protein d... | 809,443 | [
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0.3892633,
0.3276435,
0.3051214,
0.2706286,
-0.1194454... |
Interpretation of the three-dimensional structure of living nuclei by specimen tilt. | A mechanism is described that enables a specimen to be tilted through a known angle and continuously observed under the highest power of the optical microscope. Objects can thus be localized accurately in space. This facility in conjunction with serial optical sectioning by Nomarski optics has been used to construct mo... | 809,453 | [
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0.008227214,
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0.06562069,
0.4230342,
0.2486617,
0.02937643,... |
Microprobe measurements of calcium binding in the contractile spasmoneme of a vorticellid. | By means of an electron microprobe, the calcium content of isolated contractile organelles (spasmonemes) from the ciliate Zoothamnium was compared in extension and contraction. By using calcium buffers of different total concentrations, it was shown that the calcium in extended organelles was almost entirely due to con... | 809,455 | [
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0.03481561,
0.4377623,
0.2918814,
0.1153879,
-0.1... |
Comparative susceptibility of eleven mammalian cell lines to infection with trachoma organisms. | Eleven mammalian cell lines, HeLa 229, HeLa M, Hep-2, FT, BHK-21, Vero, MK-2, MPK, L-WO5A2, McCoy, and L-929, were tested for their susceptibility to infection with Trachoma strains TW-3 (type C, ocular origin) and UW-5 (type E, genital origin). All the cell layers were pretreated with diethylaminoethyl-dextran before ... | 809,479 | [
-0.2858981,
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0.4522864,
0.6546713,
0.338838,
-0.1956767,
0.3453... |
Proliferation gradients in the inner ear of the monkey (Macaca mulatta) embryo. | Radioautographic studies were conducted on early developmental stages of the inner ear in monkey (Macaca mulatta) embryos ranging in age from stage 11 to stage 20 (25 to 39 days' gestation) and labeled for one hour with [3H] thymidine. The most active period of proliferation occurred at stage 13, at which time all regi... | 809,493 | [
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0.09414229,
... |
Expression of homeotic mutations in duplicated and regenerated antennae of Drosophila melanogaster. | Three homeotic mutants, aristapedia (ssa and ssa-UCl) and Nasobemia (Ns) which involve antenna-leg transformations were analyzed with respect to their time of expression. In particular we studied the question of whether these mutations are expressed when the mutant cells pass through additional cell divisions in cultur... | 809,524 | [
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0.4703768,
0.1230032,
-0.06955... |
Partial characterization of the shift from IgG to IgA synthesis in the clonal differentiation of human leukemic bone marrow-derived lymphocytes. | An unusual B-cell proliferation was noted in an individual (Tun) which was characterized by the presence of two separate populations of chronic lymphocytic leukemia (CLL) cell staining on the surface and in the cytoplasm for either IgG(k) or IgA(k). Utilizing an idiotypic antiserum prepared from the associated serum mo... | 809,529 | [
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0.1326646,
0.4657957,
0.05836855,
-0.04059... |
Phenogenetics of a suppressor and an enhancer gene of the lozenge34k allel of Drosophila melanogaster. | The recessive sex-linked gene, lozenge34k, was initially identified on the basis of its effect on the compound eye of Drosophila melanogaster. However, its pleiotropic effects include modification of the antennae, legs and female reproductive structures as well. Two modifier genes, a third chromosome suppressor, su(lz3... | 809,533 | [
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0.1482296,
0.6894181,
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... |
Quantal basis of photoreceptor spectral sensitivity of Drosophila melanogaster. | Small potential fluctuations ("bumps"), boyh spontaneous and light induced, can be recorded intracellularly from the photoreceptors of Drosophila melanogaster. Statistical analyses of these bumps in the spectral range, 400-600 nm, lead to the following interpretations; (a) For weak stimuli at least, these bumps are the... | 809,537 | [
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0.294713,
0.4891622,
0.0024365... |
Immunomodification and the expression of virulence in mice by defined strains of Semliki Forest virus: the effects of myocrisin and 1-asparaginase. | Studies in mice of the modes of immunomodification imposed by cyclophosphamide, have been extended to comparative studies with Myocrisin, 1-asparaginase and interferon. It has been shown for mice infected i.p. or i.c. by an avirulent clone of SFV, that the potentiation of disease may be marked by many distinct changes ... | 809,543 | [
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0.1003514,
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[Difficulties in genetic counseling in phakomatosis]. | It is often difficult to establish a valid pedigree in a family, a member of which shows one or another phakomatosis. It is indispensable to examine all the members of the family in order to detect the "formes frustes" or the atypical and abortive forms, which are frequent, and in order to establish a genetic prognosis... | 809,545 | [
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... |
Physiologic characteristics of vestibular first-order canal neurons in the cat. II. Response to constant angular acceleration. | The physiologic response of first-order vestibular canal neurons, recorded within the internal auditory canal with glass microelectrodes, was studied in anesthetized cats. Neurons from all three canals were subjected to velocity trapezoidal rotations about the canal axis, and about different axes extending up to 90 deg... | 809,548 | [
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0.1513412,
0.09559284,... |
Calcium fluxes in internally dialyzed giant barnacle muscle fibers. | Calcium-45 fluxes have been examined in isolated giant barnacle muscle fibers subjected to internal solute control by means of "internal dialysis". The 45Ca efflux was dependent upon the concentrations of both total and ionized internal Ca (Ca2+ buffered with EGTA). With a total Ca concentration of 2.0 mM and a 1:2 Ca/... | 809,588 | [
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0.3138975,
0.1526853,
0... |
Detection and preparation of immunoglobulin (Ig) mu chain protein in sera of patients with heavy chain diseases (HCD). | The detection of Igmu chain proteins in the serum of a patient with HCD by a combining of starch gel electrophoresis and immunodiffusion is described. Partial isolation of mu chain protein by immunoadsorbtion on polyacrylamide gel has been acchieved. As no contaminations of mu chain protein with IgM protein could be de... | 809,615 | [
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... |
[Acetylcholinesterase activity of bacteria of the genus Pseudomonas]. | The activity of acetylcholine esterase was determined in 50 strains of the Pseudomonas genus: Ps. aurantiaca (6 strains), Ps. aeruginosa (8 strains), Ps. fluorescens (31 strains), Ps. putida (1 strain), Ps. ovalis (1 strain), Ps. aureofaciens (1 strain), Ps. geniculata (1 strain), and Ps. nonliquefaciens (1 strain). Th... | 809,648 | [
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0.2669192,
0.3072823,
0.1307191,
0.02145903,
-0.1504479... |
The ribosomal proteins of Drosophila melanogaster. V. Analysis by two-dimensional gel electrophoresis of the ribosomal proteins of the temperature-sensitive lethal allele of suppressor of forked, l(1) su(f)ts67g: a putative ribosomal protein mutant. | The possibility that the ribosomes of a temperature-sensitive lethal allele of suppressor of forked, l(1)su(f)ts67g, contain a mutated protein was studied by two-dimensional gel electrophoresis. The results from these analyses revealed no differences in the ribosomal proteins between the mutant and the wild-type strain... | 809,665 | [
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... |
[The operative treatment of paresis of the fibular nerve caused by external compression (author's transl)]. | The operative treatment of six cases of paresis of the fibular nerve caused by external compression in five patients are reported. From the intraoperative findings and the postoperative results, decompression of the fibular nerve with simultaneous neurolysis can be recommended as the optimal method for cases, which hav... | 809,699 | [
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0.09190635,
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[Coronary angiography in the pre-infarct syndrome (author's transl)]. | During the first ten month of the past year (1974) we did 310 selective coronary arteriographies by the Sones technique at the Department of Cardiology of the Medical Clinic Würzburg. The incidence of complications in this comparatively small group was 0%. In seven cases we did an emergency coronary arteriography. Six ... | 809,700 | [
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... |
Reduction in myocardial ischemia with nitroglycerin or nitroglycerin plus phenylephrine administered during acute myocardial infarction. | Nitroglycerin reduces ischemic injury during acute myocardial infarction (AMI) in dogs--an effect that is potentiated when drug-induced hypotension and tachycardia are prevented with phenylephrine. To determine the effectiveness of nitroglycerin, alone or with phenylephrine, during AMI in man, 12 patients (five or whom... | 809,712 | [
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Repair of U.V. damages in Bacillus subtilis cultures competent for transformation: difference between competent and non-competent fractions. | The repair of U.V. damages to DNA in B. subtilis cultures competent for genetic transformation has been studied. The comparison of survival curves for competent and non competent fractions shows that: i) excision repair is more effective in competent than in non competent bacteria; ii) recombination repair is more effe... | 809,758 | [
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Determining liver retention of transuranium elements in living beagles. | A method has been developed whereby the liver content of photon-emitting transuranium elements can be determined in living beagles by a combination of total-body and partial-body counting. Calibration of the system was accomplished through the photon counting of intact dogs and also of the parts of the same animals fol... | 809,801 | [
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[The medical implications of the accelerating increase in population]. | South Africa is on the brink of a population explosion, especially with regard to its Black citizens. The supply of adequate medical services and the successful implementation of family planning can best be achieved in a practical way by the development of advanced nursing on a large scale. | 809,850 | [
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Bone marrow transplantation in the busulfan-treated rat. II. Effect of cyclophosphamide and antithymic serum on the presensitized state. | The purpose of the present study was to develop a model in the busulfan (BU)-treated aplastic rat for investigating sensitization to donor marrow in various donor and recipient combinations differing in their degree of histocompatibility. In addition, cyclophosphamide (CY) and rabbit antirat thymocyte serum (RARTS) wer... | 809,876 | [
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The metabolic fate of endrin in the rabbit. | 1. [14C]Endrin, administered orally to rabbits, is excreted in the faeces as unchanged endrin (50% of that administered) and in the urine as a mixture of polar metabolites. 2. The major biotransformation is hydroxylation at the methylene bridge (C-12) to yield anti-12-hydroxyendrin. syn-Hydroxylation at C-12 also occur... | 809,931 | [
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Histophysiological evidence for the secretion of polypeptides by the pineal gland. | Histophysiological examinations of the bovine and monkey pineal gland indicate that this organ may be involved in the secretion of polypeptides. Using various histochemical procedures designed to identify peptide-secreting cells, granules and/or droplets of presumptive secretory product were identified within cellular ... | 810,015 | [
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0.105966... |
Fetal and maternal risks associated with intrauterine transfusion procedures. | Continuing follow-up observations and study of information as derived from a large cohort of fetal recipients of intrauterine transfusion (IUT) is utilized to provide estimates of maternal and fetal risks associated with the transfusion procedures, subsequent maternal complications of the pregnancy, and the health, int... | 810,023 | [
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Multivariate analysis of early hominid pelvic bones. | Multivariate analyses of the acetabular and iliac parts of fossil hominid and extant hominoid pelvic bones show that (1) the best preserved fossil from Swartkrans (SK 3155) is more similar to the Sterkfontein pelvis (Sts 14) than either fossil is to any extant hominoid species; (2) of the living hominoids, all of the f... | 810,038 | [
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Degradation of 3-hydroxybenzoate by bacteria of the genus Bacillus. | The pathway whereby certain bacterial strains of the genus Bacillus degrade m-hydroxybenzoate is delineated. Of 12 strains examined, nine were tentatively classified as representatives of the species Bacillus brevis, two of Bacillus sphaericus and one of Bacillus megaterium. All strains degraded m-hydroxybenzoate via t... | 810,087 | [
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[Pharmacodynamic study of myocardial contraction using ultrasonic echography during isoproterenol perfusion in the normal subject]. | An echographic study, both before and under isoproterenol infusion, was performed on 50 normal subjects. The movements of the posterior wass of the left ventricle were found to be averagely increased of 62% as regards the amplitude, 114% for the mean speed and 124% for the maximum speed of contraction. The transcerse d... | 810,105 | [
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0.01978284,... |
Experimental vitreous surgery. XIII. Open-sky partial vitrectomy through pars plana incision. | The effects of an incision through the pars plana ciliaris for open-sky subtotal vitrectomy were evaluated in four groups of monkeys, with incisions ranging from 170 degrees to 240 degrees. The nasal long ciliary artery and nerve and the anterior ciliary arteries from the inferior and medial recti were left intact in a... | 810,121 | [
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Polarographic assay and intracellular distribution of superoxide dismutase in rat liver. | 1. A polarographic assay of superoxide (O2--) dismutase (EC 1.15.1.1) activity is described, in which the ability of the enzyme to inhibit O2---dependent sulphite oxidation, initiated by xanthine oxidase activity, is measured. The assay was used in a study of the intracellular distribution of superoxide dismutase in ra... | 810,138 | [
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The hydroxylation of tyrosine by an enzyme from third-instar larvae of the blowfly Calliphora erythrocephala. | 1. Two pro-(phenol oxidase) were distinguished when the blood of late-third-instar larvae of Calliphora erythrocephala was electrophoresed in polyacrylamide gels with Tris-glycine buffer, pH 8.3. One pro-(phenol oxidase), after activation by an enzyme readily catalyses the oxidation of both L-tyrosine and L-3,4-dihydro... | 810,140 | [
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Comparison of the effects of zinc deprivation and actinomycin D on ribonucleic acid synthesis by stimulated lymphocytes. | 1. EDTA inhibited incorporation of [3H]uridine into RNA of lymphocytes, but did not decrease uptake into the cold-acid-soluble fraction of the cells. The inhibition by EDTA was largely reversible by simultaneous addition of Zn2+. 2. Low concentrations pf actinomycin D (3 ng/ml) added at the time of stimulation of the c... | 810,142 | [
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Differential effects of 8-anilino-1-naphthalenesulfonate upon binding of oxidized and reduced flavines by bacterial luciferase. | Upon binding to bacterial luciferase, both the absorption and the fluorescence excitatiom maxima of 8-anilino-1-naphthalensulfonate (ANS) shift from 353 to 370 nm while the fluorescence emission optimum shifts from 540 to 480 nm, and the fluorescence quantum yield increases from 0.003 to 0.39, indicating that the envir... | 810,158 | [
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Partial purification of endonuclease activity from human lymphoblasts. Separation of activities for depurinated DNA and DNA irradiated with ultraviolet light. | Crude extracts of cultured human lymphoblasts (CCRF-CEM) contain endonuclease activity that cleaves ultraviolet-irradiated DNA in preference to untreated DNA. Purification of this activity was carried out using ultraviolet-irradiated PM2 phage DNA (5000 ergs/mm2) as substrate in the enzyme assay. Since endonuclease spe... | 810,175 | [
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The frequency distribution of heavy chain classes and light chain types of 1,000 monoclonal immunoglobulins. | In 1000 patients with monoclonal gammapathies, heavy and light chains typing of the monoclonal Ig was performed. Class distribution of the heavy chains showed the following percentages : IgG = 56.60%; IgA = 17.0%; IgM = 14.5%; IgD = 0.3%; Light chain gammapathies (including Bence-Jones proteinuria without serum M-compo... | 810,190 | [
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Spatial and chromatic properties of neurons subserving foveal and parafoveal vision in rhesus monkey. | The response properties of neurons in the region of striate cortex subserving central retina (0 degrees-2 degrees) and in a region of representation of parafoveal retina (4 degrees-7 degrees) were studied in unanesthetized paralyzed macaque monkeys. Neurons sensitive to the orientation of the stimulus in the visual fie... | 810,220 | [
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Isolation and characterization of polyribosomes from the salivary glands of Rhynchosciara americana. | Polyribosomes were obtained in high yield from Rhynchosciara salivary glands by a method which uses the non-ionic detergent Nonidet P 40, in moderate salt buffer and DTT as RNase inhibitor. The polysomal profiles from glands of animals which have just started to spin the communal cocoon are slightly but consistently di... | 810,248 | [
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Direct visual input to the limbic system: crossed retinal projections to the nucleus anterodorsalis thalami in the tree shrew. | Evidence for a direct projection from the retina to the nucleus anterodorsalis thalami in the insectivore, Tupaia glis, is presented. 100 muCi tritiated amino acid or amino acid/monosaccharide cocktail were administered as two separate intravitreal injections of 50 muCi each. Fibers were traced using thawmount autoradi... | 810,358 | [
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[IgD-multiple myeloma. Review of 102 cases reported in the literature (author's transl)]. | Reports on 102 patients suffering from IgD-myeloma are reviewed and analyzed. Patients with IgD-myeloma are younger than patients with myeloma producing IgG or IgA myeloma proteins. Males are affected by this disease 3 times as often as females and 11 times as often as female patients in the group producing kappa ligh... | 810,409 | [
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Regulation of protein metabolism in relation to adequacy of intake. | The daily flux of amino acids in the body is extensive. Protein synthesis is estimated to be 300 g daily in an adult man. This requires uptake and release of 150 g essential amino acids, yet the dietary requirement for essential amino acids in only 6 g. This indicates extensive and efficient recycling of essential amin... | 810,422 | [
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... |
[Metabolic behavior in total parenteral nutrition during the postoperative phase]. | In patients who had undergone gastric operation, total postoperative parenteral nutrition was effected using a combination of two infusion solutions having complementary constituents. 80 g L-amino acids and about 2,500 kcal in the form of a glucose-levulose-xylitol mixture together with electrolytes and trace elements ... | 810,432 | [
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0.04664024,
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[Nitrogen balance in routine surgical interventions with the use of Vivasorb]. | With Vivasorb, the surgical patient's full alimentation can be maintained up to a few hours before the operation. In the postoperative phase, the nitrogen balance of patients having undergone minor surgical intervention and in a state of moderate catabolism can be kept under control in a slightly negative range by the ... | 810,436 | [
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0.2300254,
0.02349906... |
Effects of allergy, intestinal helminthic infestation and sex on serum IgE concentrations and immediate skin hypersensitivity in three ethnic groups. | Serum IgE concentrations were measured in 232 blood donors resident in the Western Cape, South Africa. Subjects were interviewed for histories of allergy and skin tested with a variety of common allergens. Faecal specimens were collected for microscopic examination. Results confirmed that Cape Coloureds and Africans te... | 810,437 | [
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0.5397592,
-0.2573... |
Comparative inhibitory effects of serum on lymphocyte responses to mitogenic stimulation. | The effects of sera from pregnant women, human umbilical cords and nonpregnant healthy control individuals on human lymphocyte responses to phytohemagglutinin (PHA), pokeweed mitogen (PWM) and allogeneic lymphocytes (MLR) are described. Maternal sera invariably inhibited lymphocyte responses to PHA. In MLR and PWM-stim... | 810,440 | [
0.1382008,
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-0.2160223,
-0.2153554,
0.3397507,
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0.1031451,
0.3561811,
0.2165977,
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0.3860095,
0.1303103,
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0.03819115,
0.4771053,
0.2093413,
0.152086,
-0.1859263,
-0... |
Glycoproteins secreted by sublingual glands of the echidna (Tachyglossus aculeatus). | The portion of echnida sublingual glycoproteins which could be solubilized was fractionated by electrophoresis in polyacrylamide gel and by filtration on a column of Sephadex G-100. Analyses for carbohydrate and amino acid are given and are compared with those of the submaxillary mucins of cattle, dog, pig and sheep. T... | 810,442 | [
-0.1129706,
-0.3636147,
0.2018244,
0.02284223,
0.001971612,
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0.09569792,
0.1009813,
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0.2629897,
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0.1220263,
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-0.1741046,
0.04919926,
0.06150782,
0.4403057,
-0.0253202,
-0.05033539,
... |
Optic nerve circulation and ocular pressure. | Rapid, short-lasting elevation of ocular pressure level produces simultaneous reduction in blood-flow rate in the distal 6 mm. of the extraocular portion of the optic nerve of the rhesus monkey as monitored by the heated thermocouple technique. The magnitude of this reduction was very small until intraocular pressure (... | 810,450 | [
-0.09563577,
-0.1006955,
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-0.03808738,
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0.1228812,
0.1103088,
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0.05225743,
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0.1185087,
-0.3479499,
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-0.5219849,
0.1794394,
0.2100748,
0.05120505,
-0.05217993,
0.2420714,
0.1215817,
... |
CI-744 anesthesia for ophthalmological examination and surgery in monkeys. | CI-744 is a new agent for chemical restraint and surgical anesthesia in animals, consisting of equal parts by weight of the cataleptoid agent tiletamine-HCl and the tranquilizer zolazepam-HCl. We have used it in the intramuscular dose of five to ten milligrams per kilogram to anesthetize 110 cynomolgus and 10 vervet mo... | 810,453 | [
-0.05495091,
0.04812025,
-0.2952105,
-0.7531124,
-0.08063148,
-0.3609601,
-0.2848196,
0.03516134,
0.16048,
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0.08906155,
0.2967944,
0.1041824,
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0.1593214,
0.06044034,
-0.7909284,
0.3313152,
0.2209402,
0.3421481,
0.1364242,
0.3266007,
-0.0810817,
-0... |
Leucine biosynthesis in the blue-green bacterium Anacystis nidulans. | Leucine-requiring auxotrophs of the unicellular blue-green bacterium Anacystis nidulans have been isolated. Extracts of these mutants were deficient in alpha-isopropylmalate synthetase (EC 4.1.3.12). In wild-type cells, this enzyme was subject to feedback inhibition by leucine. However, formation of the enzymes of leuc... | 810,483 | [
-0.3746839,
-0.3696541,
-0.2549517,
-0.01370712,
0.1669135,
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0.1464201,
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0.0773218,
0.1862896,
-0.2134972,
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0.1340982,
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0.2075837,
-0.1114588,
-0.04407067,
0.1090396,
0.4900322,
-0.07538412,
... |
Use of immunoglobulin coupled to agarose beads for examining the specificity of conjugates. | Preparations of purified immunoglobulins, light chains, and unrelated proteins (used as controls) were covalently linked to agarose beads and used to study the specificity of fluorescein isothiocyanate conjugates. The data demonstrate how these beads can be used to detect immunological and non-immunological reactivity ... | 810,493 | [
-0.07225537,
0.202519,
-0.01150826,
0.09119603,
0.283644,
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-0.1756402,
0.4296409,
0.05106252,
0.2902391,
0.1188603,
0.1275883,
0.1879051,
0.04421034,
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0.3064361,
-0.06880483,
0.04161496,
0.2402973,
-0.03049759,
-0.05577559,
... |
A modified polyriboinosinic-polyribocytidylic acid complex that induces interferon in primates. | A comlex of polyriboinosinic-polyribocytidylic acid (poly I-poly C) with poly-L-lysine and carboxymethylcellulose has been prepared. This complex is five to 10 times as resistant to hydrolysis by primate serum as the parent poly I-poly C. It has a thermal denaturation temperature about 40 C higher than that of poly I-p... | 810,520 | [
-0.07721021,
0.06836022,
-0.07067505,
0.1609266,
0.1019779,
-0.1010676,
-0.3447737,
0.07868805,
0.3290727,
0.1403418,
0.1061645,
-0.1724329,
0.1801448,
0.2216911,
-0.3200276,
-0.3908294,
-0.2703826,
-0.1227565,
-0.0360129,
0.3706969,
0.195977,
0.02285368,
-0.0424176,
-0... |
Studies on human malaria in Aotus monkeys. VI. Infectivity of Plasmodium malariae to different Anophelines. | Anopheles freeborni, A. balabacensis balabacensis, A. atroparvus, A. stephensi, and A. maculatus mosquitoes were infected by feeding on 12 Aotus trivirgatus monkeys infected with a Nigerian strain of Plasmodium malariae. Comparative infectivity studies indicated that the first 2 species were the most heavily infected. | 810,562 | [
-0.06669671,
0.0953844,
-0.0286716,
0.04060952,
0.1115857,
-0.2171505,
-0.1270754,
-0.0659935,
0.09544563,
-0.4089444,
0.3258044,
0.02330389,
-0.0177775,
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-0.5602959,
0.1767853,
-0.1246503,
-0.1466963,
0.008196387,
0.1664063,
-0.09239657... |
Fluorocarbon aerosol propellants. VI: Interspecies differences in solubilities in blood and plasma and their possible implications in toxicity studies. | Solubilities of the three most commonly used fluorocarbon aerosol propellants were determined in the blood and plasma of humans, monkeys, dogs, rats, and mice. Differences as large as approximately fourfold in blood and more than 33-fold in plasma were found in different species. The partitioning of fluorocarbons betwe... | 810,571 | [
-0.4712757,
0.1756421,
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0.2333866,
-0.1027638,
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0.1215895,
0.2142168,
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0.141168,
0.1356267,
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0.02814508,
0.141673,
-0.2398787,
0.4977823,
-0.01435892,
0.2076861,
0.1104772,
-0.288... |
Metabolic disposition and cardiovascular effects of methyldopate in unanesthetized rhesus monkeys. | Methyldopate, the ethyl ester hydrochloride salt of alpha-methyldopa (alpha-MD), is used extensively in the treatment of severe hypertension. We have developed a high-pressure liquid chromatographic assay to determine the plasma-time concentrations of alpha-MD after intravenous administration of methyldopate and alpha-... | 810,574 | [
-0.4443598,
-0.06353111,
-0.4739462,
-0.2238058,
0.03229515,
-0.3040481,
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-0.02480071,
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0.2475883,
0.3166201,
0.2620296,
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-0.5146539,
0.1105035,
0.105712,
0.2667061,
0.2601332,
-0.01037361,
-0.009636,
... |
Mason-Pfizer monkey virus: analysis and localization of virion proteins and glycoproteins. | The polypeptide composition of Mason-Pfizer monkey virus was determined using sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Six major polypeptides of molecular weights 68,000, 27,000, 20,000, 14,000, 12,000, and 10,000 were resolved regardless of the cell type (i.e., two human and two rhesus) in which the ... | 810,603 | [
-0.09733487,
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0.2496276,
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0.02711653,
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0.1170787,
-0.154358,
0.08988442,
0.004112708,
0.0784388,
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-0.4171229,
0.08379152,
0.2041389,
-0.196058,
0.0009960354,
0.3070366,
-0.01... |
A survey of Sarcocystis in nonhuman primates. | Of the 375 wild-caught Old World and New World monkeys examined in this survey, 79 (21%) were infected with Sarcocystis, while 369 laboratory-born animals were negative. Four strucutrally different types of sarcocysts were observed; 2 were probably new species. New host records were recognized for 4 species of Asian ma... | 810,620 | [
-0.01244211,
-0.2326742,
0.1787532,
-0.1914527,
-0.1362512,
0.06400788,
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0.1686618,
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0.0863261,
0.2152807,
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-0.7646744,
0.0397055,
0.1410094,
-0.02255857,
-0.0996679,
0.2591257,
0.05455242,... |
Seizures in adolescents. | The management of a patient with seizures involves proper classification, etiologic evaluation, and administration of appropriate therapy. With proper evaluation and management, control of seizures can be expected in the majority of patients. The physician must realize that an epileptic adolescent has intrinsic anxieti... | 810,630 | [
-0.1218251,
0.3514289,
-0.04948467,
-0.1653809,
0.1050232,
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-0.07418675,
0.0176052,
0.05240846,
0.0847917,
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0.04880629,
-0.1676012,
0.07133541,
-0.006299922,
0.1133955,
-0.2613199,
0.01675151,
-0.134345... |
Bacteriophage SPO1 DNA- and RNA-directed protein synthesis in vitro: the effect of TF1, a template-selective transcription inhibitor. | Transcription factor one (TF1), a protein synthesized after infection of B. subtilis by phage SPO1, is a specific inhibitor of SPO1 in vitro transcription. In this paper, we investigate the effect of TF1 on SPO1-specific in vitro protein synthesis, using SPO1 DNA or messenger RNA as templates. Protein syhthesis is meas... | 810,655 | [
-0.1646176,
-0.245693,
-0.244347,
-0.2257229,
0.1920326,
-0.2742995,
-0.07519937,
-0.1581143,
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-0.1249434,
0.1316142,
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0.1436559,
-0.3573276,
0.0832145,
-0.3045827,
0.1241151,
0.6776695,
0.1363528,
-0.2599418,... |
A new mutant of Bacillus subtilis altered in the initiation of chromosome replication. | We have isolated a new mutant of Bacillus subtilis temperature sensitive in DNA replication; its properties are those of an initiation mutant. When liquid cultures are shifted to 48 degrees DNA replication is the first macromolecular synthesis that stops, but only after synthesis of the amount of DNA predicted for the ... | 810,658 | [
-0.07376871,
-0.2326718,
-0.1473766,
-0.01608947,
-0.2704666,
-0.3786554,
-0.1806328,
-0.2160813,
0.2781488,
0.2570992,
0.1258837,
-0.07089575,
-0.0767865,
0.1660042,
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0.3315801,
0.01926813,
-0.4951658,
0.03794302,
0.2905353,
0.3649482,
-0.07414494,
-0.1817347,... |
Ribosomal proteins from streptomycin-resistant and dependent mutants, and revertants from streptomycin-dependence to independence in Bacillus subtilis. | Streptomycin-resistant and dependent mutants were isolated from Bacillus subtilis ATCC 6633. Ribosomal proteins were analysed from six such mutants with chromatography on carboxymethyl cellulose or phosphocellulose columns. An altered specific 30s ribosomal protein, 30B, could be detected in all of these mutants. Strep... | 810,662 | [
0.1334284,
0.3159383,
0.1911256,
-0.07515217,
-0.1846759,
-0.01136822,
-0.1511661,
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0.3457347,
0.01089495,
0.1777789,
0.1797344,
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0.05629207,
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0.1703032,
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0.05806715,
0.4466943,
-0.02660637,
0.1469552,
... |
[Our programmed headache medical record. Contribution to the systematic registration and processing of a larger amount of headache patients using the computer]. | We present a detailed anterospective inventory on headache which has been developed systematically with several alterations in the course of the experience of several years. It offers the possibility of an almost complete collection of data which can be fed directly into a computer and it appears to be a valuable aid i... | 810,676 | [
-0.2135298,
0.2187876,
0.01810302,
0.2807819,
-0.1840943,
-0.4972639,
-0.3611435,
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0.09886791,
-0.2215011,
-0.04466476,
-0.1340297,
-0.05836651,
-0.539274,
-0.6526525,
-0.0774693,
-0.07943138,
0.4614137,
-0.05430345,
0.3850754,
-0.002804957,
-0.1448798,
-0.0877... |
[Damage to the spinal marrow in kyphoscoliosis (author's transl)]. | Damage to the spinal marrow by kyphoscoliosis shows a characteristic clinical syndrome: severe curvature of the vertebral column, first manifestation in the second decade or in the second half of life, at this time frequently associated with cardiac and circulatory failure, spinal symptoms often accentuated on the conv... | 810,687 | [
0.006231413,
0.1245248,
0.1435459,
-0.3559799,
0.1391666,
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-0.1944041,
0.009816257,
0.1665182,
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0.1190174,
0.007108214,
0.05292768,
0.2982214,
0.534692,
0.07379006,
-0.018723... |
[The importance of serum insulin determination in the diagnosis and treatment of diabetes mellitus (author's transl)]. | Various types of insulin secretion can be distinguished in diabetics by means of radioimmunological serum insulin determination: Overweight, subclinical diabetics with increased insulin response in the test, adult diabetics with evident insulin response and diabetics with absent insulin response following stimulation. ... | 810,689 | [
0.1799664,
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0.2635429,
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0.2361008,
0.1546332,
0.3085245,
0.1425423,
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0.06085864,
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-0.1162006,
0.148741,
-0.1375298,
0.435216,
0.3082429,
-0.01442475,
-0.002922644,
-0... |
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